BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|194306567 replication factor C 5 isoform 2 [Homo sapiens] (319 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|194306571 replication factor C 5 isoform 2 [Homo sapiens] 627 e-180 gi|194306567 replication factor C 5 isoform 2 [Homo sapiens] 627 e-180 gi|6677723 replication factor C 5 isoform 1 [Homo sapiens] 625 e-179 gi|194306569 replication factor C 5 isoform 3 [Homo sapiens] 498 e-141 gi|31881687 replication factor C 4 [Homo sapiens] 210 1e-54 gi|4506491 replication factor C 4 [Homo sapiens] 210 1e-54 gi|31563534 replication factor C 2 isoform 1 [Homo sapiens] 209 2e-54 gi|28882049 replication factor C 2 isoform 2 [Homo sapiens] 162 3e-40 gi|108773789 replication factor C 3 isoform 2 [Homo sapiens] 100 2e-21 gi|4506489 replication factor C 3 isoform 1 [Homo sapiens] 100 2e-21 gi|27501458 CTF18, chromosome transmission fidelity factor 18 ho... 51 1e-06 gi|32528306 replication factor C large subunit [Homo sapiens] 50 3e-06 gi|18426902 Werner helicase interacting protein isoform 1 [Homo ... 48 1e-05 gi|19718796 RAD17 homolog isoform 1 [Homo sapiens] 46 5e-05 gi|19718794 RAD17 homolog isoform 1 [Homo sapiens] 46 5e-05 gi|19718792 RAD17 homolog isoform 1 [Homo sapiens] 46 5e-05 gi|19718784 RAD17 homolog isoform 1 [Homo sapiens] 46 5e-05 gi|4506383 RAD17 homolog isoform 1 [Homo sapiens] 46 5e-05 gi|19718786 RAD17 homolog isoform 2 [Homo sapiens] 46 5e-05 gi|18426904 Werner helicase interacting protein isoform 2 [Homo ... 43 4e-04 gi|4502703 cell division cycle 6 protein [Homo sapiens] 37 0.018 gi|21361144 proteasome 26S ATPase subunit 3 [Homo sapiens] 37 0.023 gi|194018490 ATPase family, AAA domain containing 3C [Homo sapiens] 37 0.023 gi|26080431 ATPase family, AAA domain containing 5 [Homo sapiens] 36 0.040 gi|119964730 BCS1-like [Homo sapiens] 35 0.068 gi|4757852 BCS1-like [Homo sapiens] 35 0.068 gi|75677353 AAA-ATPase TOB3 [Homo sapiens] 35 0.088 gi|31377667 peroxisomal LON protease-like [Homo sapiens] 34 0.20 gi|42476028 ATPase family, AAA domain containing 3A [Homo sapiens] 34 0.20 gi|229577436 spermatogenesis associated 5-like 1 [Homo sapiens] 33 0.26 >gi|194306571 replication factor C 5 isoform 2 [Homo sapiens] Length = 319 Score = 627 bits (1618), Expect = e-180 Identities = 319/319 (100%), Positives = 319/319 (100%) Query: 1 MVEKYRPQTLNDLISHQDILSTIQKFINEDRLPHLLLYGPPGTGKTSTILACAKQLYKDK 60 MVEKYRPQTLNDLISHQDILSTIQKFINEDRLPHLLLYGPPGTGKTSTILACAKQLYKDK Sbjct: 1 MVEKYRPQTLNDLISHQDILSTIQKFINEDRLPHLLLYGPPGTGKTSTILACAKQLYKDK 60 Query: 61 EFGSMVLELNASDDRGIDIIRGPILSFASTRTIFKKGFKLVILDEADAMTQDAQNALRRV 120 EFGSMVLELNASDDRGIDIIRGPILSFASTRTIFKKGFKLVILDEADAMTQDAQNALRRV Sbjct: 61 EFGSMVLELNASDDRGIDIIRGPILSFASTRTIFKKGFKLVILDEADAMTQDAQNALRRV 120 Query: 121 IEKFTENTRFCLICNYLSKIIPALQSRCTRFRFGPLTPELMVPRLEHVVEEEKVDISEDG 180 IEKFTENTRFCLICNYLSKIIPALQSRCTRFRFGPLTPELMVPRLEHVVEEEKVDISEDG Sbjct: 121 IEKFTENTRFCLICNYLSKIIPALQSRCTRFRFGPLTPELMVPRLEHVVEEEKVDISEDG 180 Query: 181 MKALVTLSSGDMRRALNILQSTNMAFGKVTEETVYTCTGHPLKSDIANILDWMLNQDFTT 240 MKALVTLSSGDMRRALNILQSTNMAFGKVTEETVYTCTGHPLKSDIANILDWMLNQDFTT Sbjct: 181 MKALVTLSSGDMRRALNILQSTNMAFGKVTEETVYTCTGHPLKSDIANILDWMLNQDFTT 240 Query: 241 AYRNITELKTLKGLALHDILTEIHLFVHRVDFPSSVRIHLLTKMADIEYRLSVGTNEKIQ 300 AYRNITELKTLKGLALHDILTEIHLFVHRVDFPSSVRIHLLTKMADIEYRLSVGTNEKIQ Sbjct: 241 AYRNITELKTLKGLALHDILTEIHLFVHRVDFPSSVRIHLLTKMADIEYRLSVGTNEKIQ 300 Query: 301 LSSLIAAFQVTRDLIVAEA 319 LSSLIAAFQVTRDLIVAEA Sbjct: 301 LSSLIAAFQVTRDLIVAEA 319 >gi|194306567 replication factor C 5 isoform 2 [Homo sapiens] Length = 319 Score = 627 bits (1618), Expect = e-180 Identities = 319/319 (100%), Positives = 319/319 (100%) Query: 1 MVEKYRPQTLNDLISHQDILSTIQKFINEDRLPHLLLYGPPGTGKTSTILACAKQLYKDK 60 MVEKYRPQTLNDLISHQDILSTIQKFINEDRLPHLLLYGPPGTGKTSTILACAKQLYKDK Sbjct: 1 MVEKYRPQTLNDLISHQDILSTIQKFINEDRLPHLLLYGPPGTGKTSTILACAKQLYKDK 60 Query: 61 EFGSMVLELNASDDRGIDIIRGPILSFASTRTIFKKGFKLVILDEADAMTQDAQNALRRV 120 EFGSMVLELNASDDRGIDIIRGPILSFASTRTIFKKGFKLVILDEADAMTQDAQNALRRV Sbjct: 61 EFGSMVLELNASDDRGIDIIRGPILSFASTRTIFKKGFKLVILDEADAMTQDAQNALRRV 120 Query: 121 IEKFTENTRFCLICNYLSKIIPALQSRCTRFRFGPLTPELMVPRLEHVVEEEKVDISEDG 180 IEKFTENTRFCLICNYLSKIIPALQSRCTRFRFGPLTPELMVPRLEHVVEEEKVDISEDG Sbjct: 121 IEKFTENTRFCLICNYLSKIIPALQSRCTRFRFGPLTPELMVPRLEHVVEEEKVDISEDG 180 Query: 181 MKALVTLSSGDMRRALNILQSTNMAFGKVTEETVYTCTGHPLKSDIANILDWMLNQDFTT 240 MKALVTLSSGDMRRALNILQSTNMAFGKVTEETVYTCTGHPLKSDIANILDWMLNQDFTT Sbjct: 181 MKALVTLSSGDMRRALNILQSTNMAFGKVTEETVYTCTGHPLKSDIANILDWMLNQDFTT 240 Query: 241 AYRNITELKTLKGLALHDILTEIHLFVHRVDFPSSVRIHLLTKMADIEYRLSVGTNEKIQ 300 AYRNITELKTLKGLALHDILTEIHLFVHRVDFPSSVRIHLLTKMADIEYRLSVGTNEKIQ Sbjct: 241 AYRNITELKTLKGLALHDILTEIHLFVHRVDFPSSVRIHLLTKMADIEYRLSVGTNEKIQ 300 Query: 301 LSSLIAAFQVTRDLIVAEA 319 LSSLIAAFQVTRDLIVAEA Sbjct: 301 LSSLIAAFQVTRDLIVAEA 319 >gi|6677723 replication factor C 5 isoform 1 [Homo sapiens] Length = 340 Score = 625 bits (1613), Expect = e-179 Identities = 318/318 (100%), Positives = 318/318 (100%) Query: 2 VEKYRPQTLNDLISHQDILSTIQKFINEDRLPHLLLYGPPGTGKTSTILACAKQLYKDKE 61 VEKYRPQTLNDLISHQDILSTIQKFINEDRLPHLLLYGPPGTGKTSTILACAKQLYKDKE Sbjct: 23 VEKYRPQTLNDLISHQDILSTIQKFINEDRLPHLLLYGPPGTGKTSTILACAKQLYKDKE 82 Query: 62 FGSMVLELNASDDRGIDIIRGPILSFASTRTIFKKGFKLVILDEADAMTQDAQNALRRVI 121 FGSMVLELNASDDRGIDIIRGPILSFASTRTIFKKGFKLVILDEADAMTQDAQNALRRVI Sbjct: 83 FGSMVLELNASDDRGIDIIRGPILSFASTRTIFKKGFKLVILDEADAMTQDAQNALRRVI 142 Query: 122 EKFTENTRFCLICNYLSKIIPALQSRCTRFRFGPLTPELMVPRLEHVVEEEKVDISEDGM 181 EKFTENTRFCLICNYLSKIIPALQSRCTRFRFGPLTPELMVPRLEHVVEEEKVDISEDGM Sbjct: 143 EKFTENTRFCLICNYLSKIIPALQSRCTRFRFGPLTPELMVPRLEHVVEEEKVDISEDGM 202 Query: 182 KALVTLSSGDMRRALNILQSTNMAFGKVTEETVYTCTGHPLKSDIANILDWMLNQDFTTA 241 KALVTLSSGDMRRALNILQSTNMAFGKVTEETVYTCTGHPLKSDIANILDWMLNQDFTTA Sbjct: 203 KALVTLSSGDMRRALNILQSTNMAFGKVTEETVYTCTGHPLKSDIANILDWMLNQDFTTA 262 Query: 242 YRNITELKTLKGLALHDILTEIHLFVHRVDFPSSVRIHLLTKMADIEYRLSVGTNEKIQL 301 YRNITELKTLKGLALHDILTEIHLFVHRVDFPSSVRIHLLTKMADIEYRLSVGTNEKIQL Sbjct: 263 YRNITELKTLKGLALHDILTEIHLFVHRVDFPSSVRIHLLTKMADIEYRLSVGTNEKIQL 322 Query: 302 SSLIAAFQVTRDLIVAEA 319 SSLIAAFQVTRDLIVAEA Sbjct: 323 SSLIAAFQVTRDLIVAEA 340 >gi|194306569 replication factor C 5 isoform 3 [Homo sapiens] Length = 255 Score = 498 bits (1283), Expect = e-141 Identities = 255/255 (100%), Positives = 255/255 (100%) Query: 65 MVLELNASDDRGIDIIRGPILSFASTRTIFKKGFKLVILDEADAMTQDAQNALRRVIEKF 124 MVLELNASDDRGIDIIRGPILSFASTRTIFKKGFKLVILDEADAMTQDAQNALRRVIEKF Sbjct: 1 MVLELNASDDRGIDIIRGPILSFASTRTIFKKGFKLVILDEADAMTQDAQNALRRVIEKF 60 Query: 125 TENTRFCLICNYLSKIIPALQSRCTRFRFGPLTPELMVPRLEHVVEEEKVDISEDGMKAL 184 TENTRFCLICNYLSKIIPALQSRCTRFRFGPLTPELMVPRLEHVVEEEKVDISEDGMKAL Sbjct: 61 TENTRFCLICNYLSKIIPALQSRCTRFRFGPLTPELMVPRLEHVVEEEKVDISEDGMKAL 120 Query: 185 VTLSSGDMRRALNILQSTNMAFGKVTEETVYTCTGHPLKSDIANILDWMLNQDFTTAYRN 244 VTLSSGDMRRALNILQSTNMAFGKVTEETVYTCTGHPLKSDIANILDWMLNQDFTTAYRN Sbjct: 121 VTLSSGDMRRALNILQSTNMAFGKVTEETVYTCTGHPLKSDIANILDWMLNQDFTTAYRN 180 Query: 245 ITELKTLKGLALHDILTEIHLFVHRVDFPSSVRIHLLTKMADIEYRLSVGTNEKIQLSSL 304 ITELKTLKGLALHDILTEIHLFVHRVDFPSSVRIHLLTKMADIEYRLSVGTNEKIQLSSL Sbjct: 181 ITELKTLKGLALHDILTEIHLFVHRVDFPSSVRIHLLTKMADIEYRLSVGTNEKIQLSSL 240 Query: 305 IAAFQVTRDLIVAEA 319 IAAFQVTRDLIVAEA Sbjct: 241 IAAFQVTRDLIVAEA 255 >gi|31881687 replication factor C 4 [Homo sapiens] Length = 363 Score = 210 bits (535), Expect = 1e-54 Identities = 122/314 (38%), Positives = 191/314 (60%), Gaps = 10/314 (3%) Query: 2 VEKYRPQTLNDLISHQDILSTIQKFINEDRLPHLLLYGPPGTGKTSTILACAKQLYKDKE 61 VEKYRP+ ++++ +++++ ++K + LP+LL YGPPGTGKTSTILA A++L+ + Sbjct: 41 VEKYRPKCVDEVAFQEEVVAVLKKSLEGADLPNLLFYGPPGTGKTSTILAAARELFGPEL 100 Query: 62 FGSMVLELNASDDRGIDIIRGPILSFASTRTIFKKG-------FKLVILDEADAMTQDAQ 114 F VLELNASD+RGI ++R + +FA + FK+VILDEAD+MT AQ Sbjct: 101 FRLRVLELNASDERGIQVVREKVKNFAQLTVSGSRSDGKPCPPFKIVILDEADSMTSAAQ 160 Query: 115 NALRRVIEKFTENTRFCLICNYLSKIIPALQSRCTRFRFGPLTPELMVPRLEHVVEEEKV 174 ALRR +EK ++ TRFCLICNY+S+II L SRC++FRF PL+ ++ RL + ++E V Sbjct: 161 AALRRTMEKESKTTRFCLICNYVSRIIEPLTSRCSKFRFKPLSDKIQQQRLLDIAKKENV 220 Query: 175 DISEDGMKALVTLSSGDMRRALNILQS-TNMAFGK-VTEETVYTCTGHPLKSDIANILDW 232 IS++G+ LV +S GD+R+A+ LQS T + GK +TE+ + G I + Sbjct: 221 KISDEGIAYLVKVSEGDLRKAITFLQSATRLTGGKEITEKVITDIAGVIPAEKIDGVFAA 280 Query: 233 MLNQDFTTAYRNITELKTLKGLALHDILTEIHLFVHRVDFPSSVRIHLLTKMADIEYRLS 292 + F + +L +G A ++ ++H V + + + K+A+++ L+ Sbjct: 281 CQSGSFDKLEAVVKDLID-EGHAATQLVNQLHDVVVENNLSDKQKSIITEKLAEVDKCLA 339 Query: 293 VGTNEKIQLSSLIA 306 G +E +QL SL A Sbjct: 340 DGADEHLQLISLCA 353 >gi|4506491 replication factor C 4 [Homo sapiens] Length = 363 Score = 210 bits (535), Expect = 1e-54 Identities = 122/314 (38%), Positives = 191/314 (60%), Gaps = 10/314 (3%) Query: 2 VEKYRPQTLNDLISHQDILSTIQKFINEDRLPHLLLYGPPGTGKTSTILACAKQLYKDKE 61 VEKYRP+ ++++ +++++ ++K + LP+LL YGPPGTGKTSTILA A++L+ + Sbjct: 41 VEKYRPKCVDEVAFQEEVVAVLKKSLEGADLPNLLFYGPPGTGKTSTILAAARELFGPEL 100 Query: 62 FGSMVLELNASDDRGIDIIRGPILSFASTRTIFKKG-------FKLVILDEADAMTQDAQ 114 F VLELNASD+RGI ++R + +FA + FK+VILDEAD+MT AQ Sbjct: 101 FRLRVLELNASDERGIQVVREKVKNFAQLTVSGSRSDGKPCPPFKIVILDEADSMTSAAQ 160 Query: 115 NALRRVIEKFTENTRFCLICNYLSKIIPALQSRCTRFRFGPLTPELMVPRLEHVVEEEKV 174 ALRR +EK ++ TRFCLICNY+S+II L SRC++FRF PL+ ++ RL + ++E V Sbjct: 161 AALRRTMEKESKTTRFCLICNYVSRIIEPLTSRCSKFRFKPLSDKIQQQRLLDIAKKENV 220 Query: 175 DISEDGMKALVTLSSGDMRRALNILQS-TNMAFGK-VTEETVYTCTGHPLKSDIANILDW 232 IS++G+ LV +S GD+R+A+ LQS T + GK +TE+ + G I + Sbjct: 221 KISDEGIAYLVKVSEGDLRKAITFLQSATRLTGGKEITEKVITDIAGVIPAEKIDGVFAA 280 Query: 233 MLNQDFTTAYRNITELKTLKGLALHDILTEIHLFVHRVDFPSSVRIHLLTKMADIEYRLS 292 + F + +L +G A ++ ++H V + + + K+A+++ L+ Sbjct: 281 CQSGSFDKLEAVVKDLID-EGHAATQLVNQLHDVVVENNLSDKQKSIITEKLAEVDKCLA 339 Query: 293 VGTNEKIQLSSLIA 306 G +E +QL SL A Sbjct: 340 DGADEHLQLISLCA 353 >gi|31563534 replication factor C 2 isoform 1 [Homo sapiens] Length = 354 Score = 209 bits (533), Expect = 2e-54 Identities = 114/306 (37%), Positives = 182/306 (59%), Gaps = 3/306 (0%) Query: 2 VEKYRPQTLNDLISHQDILSTIQKFINEDRLPHLLLYGPPGTGKTSTILACAKQLYKDKE 61 VEKYRP LN+++ ++D +S ++ F E +P++++ GPPGTGKT++IL A+ L Sbjct: 39 VEKYRPVKLNEIVGNEDTVSRLEVFAREGNVPNIIIAGPPGTGKTTSILCLARALLGPAL 98 Query: 62 FGSMVLELNASDDRGIDIIRGPILSFASTRTIFKKG-FKLVILDEADAMTQDAQNALRRV 120 +M LELNAS+DRGID++R I FA + KG K++ILDEAD+MT AQ ALRR Sbjct: 99 KDAM-LELNASNDRGIDVVRNKIKMFAQQKVTLPKGRHKIIILDEADSMTDGAQQALRRT 157 Query: 121 IEKFTENTRFCLICNYLSKIIPALQSRCTRFRFGPLTPELMVPRLEHVVEEEKVDISEDG 180 +E +++ TRF L CN KII +QSRC R+ LT ++ RL +V+E+E+V ++DG Sbjct: 158 MEIYSKTTRFALACNASDKIIEPIQSRCAVLRYTKLTDAQILTRLMNVIEKERVPYTDDG 217 Query: 181 MKALVTLSSGDMRRALNILQSTNMAFGKVTEETVYTCTGHPLKSDIANILDWMLNQDFTT 240 ++A++ + GDMR+ALN LQST FG + E V+ P + ++ +N + Sbjct: 218 LEAIIFTAQGDMRQALNNLQSTFSGFGFINSENVFKVCDEPHPLLVKEMIQHCVNANIDE 277 Query: 241 AYRNITELKTLKGLALHDILTEIHLFVHRVDFPSSVRIHLLTKMADIEYRLSVGTNEKIQ 300 AY+ + L L G + DI+ I +++ + ++ +++ G N +Q Sbjct: 278 AYKILAHLWHL-GYSPEDIIGNIFRVCKTFQMAEYLKLEFIKEIGYTHMKIAEGVNSLLQ 336 Query: 301 LSSLIA 306 ++ L+A Sbjct: 337 MAGLLA 342 >gi|28882049 replication factor C 2 isoform 2 [Homo sapiens] Length = 320 Score = 162 bits (411), Expect = 3e-40 Identities = 96/305 (31%), Positives = 159/305 (52%), Gaps = 35/305 (11%) Query: 2 VEKYRPQTLNDLISHQDILSTIQKFINEDRLPHLLLYGPPGTGKTSTILACAKQLYKDKE 61 VEKYRP LN+++ ++D +S ++ F E +P++++ GPPGTGKT++IL A+ L Sbjct: 39 VEKYRPVKLNEIVGNEDTVSRLEVFAREGNVPNIIIAGPPGTGKTTSILCLARALL-GPA 97 Query: 62 FGSMVLELNASDDRGIDIIRGPILSFASTRTIFKKGFKLVILDEADAMTQDAQNALRRVI 121 +LELNAS+ D+MT AQ ALRR + Sbjct: 98 LKDAMLELNASN---------------------------------DSMTDGAQQALRRTM 124 Query: 122 EKFTENTRFCLICNYLSKIIPALQSRCTRFRFGPLTPELMVPRLEHVVEEEKVDISEDGM 181 E +++ TRF L CN KII +QSRC R+ LT ++ RL +V+E+E+V ++DG+ Sbjct: 125 EIYSKTTRFALACNASDKIIEPIQSRCAVLRYTKLTDAQILTRLMNVIEKERVPYTDDGL 184 Query: 182 KALVTLSSGDMRRALNILQSTNMAFGKVTEETVYTCTGHPLKSDIANILDWMLNQDFTTA 241 +A++ + GDMR+ALN LQST FG + E V+ P + ++ +N + A Sbjct: 185 EAIIFTAQGDMRQALNNLQSTFSGFGFINSENVFKVCDEPHPLLVKEMIQHCVNANIDEA 244 Query: 242 YRNITELKTLKGLALHDILTEIHLFVHRVDFPSSVRIHLLTKMADIEYRLSVGTNEKIQL 301 Y+ + L L G + DI+ I +++ + ++ +++ G N +Q+ Sbjct: 245 YKILAHLWHL-GYSPEDIIGNIFRVCKTFQMAEYLKLEFIKEIGYTHMKIAEGVNSLLQM 303 Query: 302 SSLIA 306 + L+A Sbjct: 304 AGLLA 308 >gi|108773789 replication factor C 3 isoform 2 [Homo sapiens] Length = 305 Score = 100 bits (248), Expect = 2e-21 Identities = 69/223 (30%), Positives = 113/223 (50%), Gaps = 28/223 (12%) Query: 2 VEKYRPQTLNDLISHQDILSTIQKFINEDRLPHLLLYGPPGTGKTSTILACAKQLY---- 57 V+KYRP +L L H++ + ++ + PHLL+YGP G GK + I+ ++LY Sbjct: 5 VDKYRPCSLGRLDYHKEQAAQLRNLVQCGDFPHLLVYGPSGAGKKTRIMCILRELYGVGV 64 Query: 58 ---------------KDKEFGSMV----LELNASDDRGID--IIRGPILSFASTR---TI 93 K E ++ LE+N SD D +I+ + + A ++ T Sbjct: 65 EKLRIEHQTITTPSKKKIEISTIASNYHLEVNPSDAGNSDRVVIQEMLKTVAQSQQLETN 124 Query: 94 FKKGFKLVILDEADAMTQDAQNALRRVIEKFTENTRFCLICNYLSKIIPALQSRCTRFRF 153 ++ FK+V+L E D +T+DAQ+ALRR +EK+ R L CN SK+IP ++SRC R Sbjct: 125 SQRDFKVVLLTEVDKLTKDAQHALRRTMEKYMSTCRLILCCNSTSKVIPPIRSRCLAVRV 184 Query: 154 GPLTPELMVPRLEHVVEEEKVDISEDGMKALVTLSSGDMRRAL 196 + E + L V ++E +++ L S ++R+AL Sbjct: 185 PAPSIEDICHVLSTVCKKEGLNLPSQLAHRLAEKSCRNLRKAL 227 >gi|4506489 replication factor C 3 isoform 1 [Homo sapiens] Length = 356 Score = 100 bits (248), Expect = 2e-21 Identities = 69/223 (30%), Positives = 113/223 (50%), Gaps = 28/223 (12%) Query: 2 VEKYRPQTLNDLISHQDILSTIQKFINEDRLPHLLLYGPPGTGKTSTILACAKQLY---- 57 V+KYRP +L L H++ + ++ + PHLL+YGP G GK + I+ ++LY Sbjct: 5 VDKYRPCSLGRLDYHKEQAAQLRNLVQCGDFPHLLVYGPSGAGKKTRIMCILRELYGVGV 64 Query: 58 ---------------KDKEFGSMV----LELNASDDRGID--IIRGPILSFASTR---TI 93 K E ++ LE+N SD D +I+ + + A ++ T Sbjct: 65 EKLRIEHQTITTPSKKKIEISTIASNYHLEVNPSDAGNSDRVVIQEMLKTVAQSQQLETN 124 Query: 94 FKKGFKLVILDEADAMTQDAQNALRRVIEKFTENTRFCLICNYLSKIIPALQSRCTRFRF 153 ++ FK+V+L E D +T+DAQ+ALRR +EK+ R L CN SK+IP ++SRC R Sbjct: 125 SQRDFKVVLLTEVDKLTKDAQHALRRTMEKYMSTCRLILCCNSTSKVIPPIRSRCLAVRV 184 Query: 154 GPLTPELMVPRLEHVVEEEKVDISEDGMKALVTLSSGDMRRAL 196 + E + L V ++E +++ L S ++R+AL Sbjct: 185 PAPSIEDICHVLSTVCKKEGLNLPSQLAHRLAEKSCRNLRKAL 227 >gi|27501458 CTF18, chromosome transmission fidelity factor 18 homolog [Homo sapiens] Length = 975 Score = 51.2 bits (121), Expect = 1e-06 Identities = 45/193 (23%), Positives = 74/193 (38%), Gaps = 34/193 (17%) Query: 36 LLYGPPGTGKTSTILACAKQLYKDKEFGSMVLELNASDDRGIDIIRGPILSFASTRTIFK 95 LL GPPG GKT+ A+ G V+E+NASDDR ++ R I + ++ Sbjct: 371 LLCGPPGLGKTTLAHVIARHA------GYSVVEMNASDDRSPEVFRTRIEAATQMESVLG 424 Query: 96 KGFK--LVILDEADAMTQDAQNALRRVIEK--------------------------FTEN 127 G K +++DE D A N L ++ + Sbjct: 425 AGGKPNCLVIDEIDGAPVAAINVLLSILNRKGPQEVGPQGPAVPSGGGRRRRAEGGLLMR 484 Query: 128 TRFCLICNYLSKIIPALQSRCTRFRFGPLTPELMVPRLEHVVEEEKVDISEDGMKALVTL 187 C+ + + + L+ + F P P +V RL+ V + + + AL Sbjct: 485 PIICICNDQFAPSLRQLKQQAFLLHFPPTLPSRLVQRLQEVSLRQGMRADPGVLAALCEK 544 Query: 188 SSGDMRRALNILQ 200 + D+R +N LQ Sbjct: 545 TDNDIRACINTLQ 557 >gi|32528306 replication factor C large subunit [Homo sapiens] Length = 1147 Score = 50.1 bits (118), Expect = 3e-06 Identities = 64/267 (23%), Positives = 103/267 (38%), Gaps = 52/267 (19%) Query: 2 VEKYRPQTLNDLISHQDILSTIQKFI----------NEDR----------------LPHL 35 V+KY+P +L +I Q S K + +ED+ Sbjct: 587 VDKYKPTSLKTIIGQQGDQSCANKLLRWLRNWQKSSSEDKKHAKFGKFSGKDDGSSFKAA 646 Query: 36 LLYGPPGTGKTSTI-LACAKQLYKDKEFGSMVLELNASDDRGIDIIRGPILSFASTRTIF 94 LL GPPG GKT+T L C +E G +ELNASD R ++ + + +I Sbjct: 647 LLSGPPGVGKTTTASLVC-------QELGYSYVELNASDTRSKSSLKAIVAESLNNTSI- 698 Query: 95 KKGF------------KLVILDEADAMTQDAQNALRRVIEKFTENTRFCLICNYLSKIIP 142 KGF +I+DE D M + + + ++T+ +IC + P Sbjct: 699 -KGFYSNGAASSVSTKHALIMDEVDGMAGNEDRGGIQELIGLIKHTKIPIICMCNDRNHP 757 Query: 143 ALQS---RCTRFRFGPLTPELMVPRLEHVVEEEKVDISEDGMKALVTLSSGDMRRALNIL 199 ++S C RF E + + + +E + I M ++ ++ D+R+ L+ L Sbjct: 758 KIRSLVHYCFDLRFQRPRVEQIKGAMMSIAFKEGLKIPPPAMNEIILGANQDIRQVLHNL 817 Query: 200 QSTNMAFGKVTEETVYTCTGHPLKSDI 226 S A K H K DI Sbjct: 818 -SMWCARSKALTYDQAKADSHRAKKDI 843 >gi|18426902 Werner helicase interacting protein isoform 1 [Homo sapiens] Length = 665 Score = 48.1 bits (113), Expect = 1e-05 Identities = 55/232 (23%), Positives = 92/232 (39%), Gaps = 32/232 (13%) Query: 1 MVEKYRPQTLNDLISHQDIL---STIQKFINEDRLPHLLLYGPPGTGKTSTILACAKQLY 57 + + RP TL D + + ++ + + +P L+L+GPPG GKT+ A Sbjct: 227 LADTMRPDTLQDYFGQSKAVGQDTLLRSLLETNEIPSLILWGPPGCGKTTLAHIIAS--- 283 Query: 58 KDKEFGSMVLELNASDDRGIDIIRGPILSFASTRTIFKKGFKLVILDEADAMTQDAQNAL 117 K+ + L+A++ + D +R I + ++ FK+ ++ +DE + Q+ Sbjct: 284 NSKKHSIRFVTLSATNAKTND-VRDVIKQAQNEKSFFKRK-TILFIDEIHRFNKSQQDTF 341 Query: 118 RRVIEKFTENTRFCLICNYLSKIIPALQSRCTRFRFGPLTPELMVPRLE--------HVV 169 +E T N ++ AL SRC L E MV L HV+ Sbjct: 342 LPHVECGTITLIGATTENPSFQVNAALLSRCRVIVLEKLPVEAMVTILMRAINSLGIHVL 401 Query: 170 E----------------EEKVDISEDGMKALVTLSSGDMRRALNILQSTNMA 205 + E + I + + L LS GD R LN LQ +A Sbjct: 402 DSSRPTDPLSHSSNSSSEPAMFIEDKAVDTLAYLSDGDARAGLNGLQLAVLA 453 >gi|19718796 RAD17 homolog isoform 1 [Homo sapiens] Length = 670 Score = 45.8 bits (107), Expect = 5e-05 Identities = 52/250 (20%), Positives = 102/250 (40%), Gaps = 51/250 (20%) Query: 2 VEKYRPQTLNDLISHQDILSTIQKFINEDRLPH--------LLLYGPPGTGKTSTILACA 53 V+KY+P+T ++L H+ + ++ ++ L LL+ GPPG GKT+T+ + Sbjct: 81 VDKYKPETQHELAVHKKKIEEVETWLKAQVLERQPKQGGSILLITGPPGCGKTTTLKILS 140 Query: 54 KQ--LYKDKEFGSMVLELNASDDRGIDIIRGP--ILSFASTRTIFKKGF----------- 98 K+ + + ++ + D +G+ + + S +FK+ Sbjct: 141 KEHGIQVQEWINPVLPDFQKDDFKGMFNTESSFHMFPYQSQIAVFKEFLLRATKYNKLQM 200 Query: 99 ---------KLVILDEADAMTQDAQNALRRVIEKFTENTRFCLIC---------NYLSKI 140 K++++++ + L V+ K+ R LI N + Sbjct: 201 LGDDLRTDKKIILVEDLPNQFYRDSHTLHEVLRKYVRIGRCPLIFIISDSLSGDNNQRLL 260 Query: 141 IP-ALQSRC--TRFRFGPLTPELMVPRLEHVVEEE------KVDI-SEDGMKALVTLSSG 190 P +Q C + F P+ P +M+ L +V E K+ + + ++ L SG Sbjct: 261 FPKEIQEECSISNISFNPVAPTIMMKFLNRIVTIEANKNGGKITVPDKTSLELLCQGCSG 320 Query: 191 DMRRALNILQ 200 D+R A+N LQ Sbjct: 321 DIRSAINSLQ 330 >gi|19718794 RAD17 homolog isoform 1 [Homo sapiens] Length = 670 Score = 45.8 bits (107), Expect = 5e-05 Identities = 52/250 (20%), Positives = 102/250 (40%), Gaps = 51/250 (20%) Query: 2 VEKYRPQTLNDLISHQDILSTIQKFINEDRLPH--------LLLYGPPGTGKTSTILACA 53 V+KY+P+T ++L H+ + ++ ++ L LL+ GPPG GKT+T+ + Sbjct: 81 VDKYKPETQHELAVHKKKIEEVETWLKAQVLERQPKQGGSILLITGPPGCGKTTTLKILS 140 Query: 54 KQ--LYKDKEFGSMVLELNASDDRGIDIIRGP--ILSFASTRTIFKKGF----------- 98 K+ + + ++ + D +G+ + + S +FK+ Sbjct: 141 KEHGIQVQEWINPVLPDFQKDDFKGMFNTESSFHMFPYQSQIAVFKEFLLRATKYNKLQM 200 Query: 99 ---------KLVILDEADAMTQDAQNALRRVIEKFTENTRFCLIC---------NYLSKI 140 K++++++ + L V+ K+ R LI N + Sbjct: 201 LGDDLRTDKKIILVEDLPNQFYRDSHTLHEVLRKYVRIGRCPLIFIISDSLSGDNNQRLL 260 Query: 141 IP-ALQSRC--TRFRFGPLTPELMVPRLEHVVEEE------KVDI-SEDGMKALVTLSSG 190 P +Q C + F P+ P +M+ L +V E K+ + + ++ L SG Sbjct: 261 FPKEIQEECSISNISFNPVAPTIMMKFLNRIVTIEANKNGGKITVPDKTSLELLCQGCSG 320 Query: 191 DMRRALNILQ 200 D+R A+N LQ Sbjct: 321 DIRSAINSLQ 330 >gi|19718792 RAD17 homolog isoform 1 [Homo sapiens] Length = 670 Score = 45.8 bits (107), Expect = 5e-05 Identities = 52/250 (20%), Positives = 102/250 (40%), Gaps = 51/250 (20%) Query: 2 VEKYRPQTLNDLISHQDILSTIQKFINEDRLPH--------LLLYGPPGTGKTSTILACA 53 V+KY+P+T ++L H+ + ++ ++ L LL+ GPPG GKT+T+ + Sbjct: 81 VDKYKPETQHELAVHKKKIEEVETWLKAQVLERQPKQGGSILLITGPPGCGKTTTLKILS 140 Query: 54 KQ--LYKDKEFGSMVLELNASDDRGIDIIRGP--ILSFASTRTIFKKGF----------- 98 K+ + + ++ + D +G+ + + S +FK+ Sbjct: 141 KEHGIQVQEWINPVLPDFQKDDFKGMFNTESSFHMFPYQSQIAVFKEFLLRATKYNKLQM 200 Query: 99 ---------KLVILDEADAMTQDAQNALRRVIEKFTENTRFCLIC---------NYLSKI 140 K++++++ + L V+ K+ R LI N + Sbjct: 201 LGDDLRTDKKIILVEDLPNQFYRDSHTLHEVLRKYVRIGRCPLIFIISDSLSGDNNQRLL 260 Query: 141 IP-ALQSRC--TRFRFGPLTPELMVPRLEHVVEEE------KVDI-SEDGMKALVTLSSG 190 P +Q C + F P+ P +M+ L +V E K+ + + ++ L SG Sbjct: 261 FPKEIQEECSISNISFNPVAPTIMMKFLNRIVTIEANKNGGKITVPDKTSLELLCQGCSG 320 Query: 191 DMRRALNILQ 200 D+R A+N LQ Sbjct: 321 DIRSAINSLQ 330 >gi|19718784 RAD17 homolog isoform 1 [Homo sapiens] Length = 670 Score = 45.8 bits (107), Expect = 5e-05 Identities = 52/250 (20%), Positives = 102/250 (40%), Gaps = 51/250 (20%) Query: 2 VEKYRPQTLNDLISHQDILSTIQKFINEDRLPH--------LLLYGPPGTGKTSTILACA 53 V+KY+P+T ++L H+ + ++ ++ L LL+ GPPG GKT+T+ + Sbjct: 81 VDKYKPETQHELAVHKKKIEEVETWLKAQVLERQPKQGGSILLITGPPGCGKTTTLKILS 140 Query: 54 KQ--LYKDKEFGSMVLELNASDDRGIDIIRGP--ILSFASTRTIFKKGF----------- 98 K+ + + ++ + D +G+ + + S +FK+ Sbjct: 141 KEHGIQVQEWINPVLPDFQKDDFKGMFNTESSFHMFPYQSQIAVFKEFLLRATKYNKLQM 200 Query: 99 ---------KLVILDEADAMTQDAQNALRRVIEKFTENTRFCLIC---------NYLSKI 140 K++++++ + L V+ K+ R LI N + Sbjct: 201 LGDDLRTDKKIILVEDLPNQFYRDSHTLHEVLRKYVRIGRCPLIFIISDSLSGDNNQRLL 260 Query: 141 IP-ALQSRC--TRFRFGPLTPELMVPRLEHVVEEE------KVDI-SEDGMKALVTLSSG 190 P +Q C + F P+ P +M+ L +V E K+ + + ++ L SG Sbjct: 261 FPKEIQEECSISNISFNPVAPTIMMKFLNRIVTIEANKNGGKITVPDKTSLELLCQGCSG 320 Query: 191 DMRRALNILQ 200 D+R A+N LQ Sbjct: 321 DIRSAINSLQ 330 >gi|4506383 RAD17 homolog isoform 1 [Homo sapiens] Length = 670 Score = 45.8 bits (107), Expect = 5e-05 Identities = 52/250 (20%), Positives = 102/250 (40%), Gaps = 51/250 (20%) Query: 2 VEKYRPQTLNDLISHQDILSTIQKFINEDRLPH--------LLLYGPPGTGKTSTILACA 53 V+KY+P+T ++L H+ + ++ ++ L LL+ GPPG GKT+T+ + Sbjct: 81 VDKYKPETQHELAVHKKKIEEVETWLKAQVLERQPKQGGSILLITGPPGCGKTTTLKILS 140 Query: 54 KQ--LYKDKEFGSMVLELNASDDRGIDIIRGP--ILSFASTRTIFKKGF----------- 98 K+ + + ++ + D +G+ + + S +FK+ Sbjct: 141 KEHGIQVQEWINPVLPDFQKDDFKGMFNTESSFHMFPYQSQIAVFKEFLLRATKYNKLQM 200 Query: 99 ---------KLVILDEADAMTQDAQNALRRVIEKFTENTRFCLIC---------NYLSKI 140 K++++++ + L V+ K+ R LI N + Sbjct: 201 LGDDLRTDKKIILVEDLPNQFYRDSHTLHEVLRKYVRIGRCPLIFIISDSLSGDNNQRLL 260 Query: 141 IP-ALQSRC--TRFRFGPLTPELMVPRLEHVVEEE------KVDI-SEDGMKALVTLSSG 190 P +Q C + F P+ P +M+ L +V E K+ + + ++ L SG Sbjct: 261 FPKEIQEECSISNISFNPVAPTIMMKFLNRIVTIEANKNGGKITVPDKTSLELLCQGCSG 320 Query: 191 DMRRALNILQ 200 D+R A+N LQ Sbjct: 321 DIRSAINSLQ 330 >gi|19718786 RAD17 homolog isoform 2 [Homo sapiens] Length = 681 Score = 45.8 bits (107), Expect = 5e-05 Identities = 52/250 (20%), Positives = 102/250 (40%), Gaps = 51/250 (20%) Query: 2 VEKYRPQTLNDLISHQDILSTIQKFINEDRLPH--------LLLYGPPGTGKTSTILACA 53 V+KY+P+T ++L H+ + ++ ++ L LL+ GPPG GKT+T+ + Sbjct: 92 VDKYKPETQHELAVHKKKIEEVETWLKAQVLERQPKQGGSILLITGPPGCGKTTTLKILS 151 Query: 54 KQ--LYKDKEFGSMVLELNASDDRGIDIIRGP--ILSFASTRTIFKKGF----------- 98 K+ + + ++ + D +G+ + + S +FK+ Sbjct: 152 KEHGIQVQEWINPVLPDFQKDDFKGMFNTESSFHMFPYQSQIAVFKEFLLRATKYNKLQM 211 Query: 99 ---------KLVILDEADAMTQDAQNALRRVIEKFTENTRFCLIC---------NYLSKI 140 K++++++ + L V+ K+ R LI N + Sbjct: 212 LGDDLRTDKKIILVEDLPNQFYRDSHTLHEVLRKYVRIGRCPLIFIISDSLSGDNNQRLL 271 Query: 141 IP-ALQSRC--TRFRFGPLTPELMVPRLEHVVEEE------KVDI-SEDGMKALVTLSSG 190 P +Q C + F P+ P +M+ L +V E K+ + + ++ L SG Sbjct: 272 FPKEIQEECSISNISFNPVAPTIMMKFLNRIVTIEANKNGGKITVPDKTSLELLCQGCSG 331 Query: 191 DMRRALNILQ 200 D+R A+N LQ Sbjct: 332 DIRSAINSLQ 341 >gi|18426904 Werner helicase interacting protein isoform 2 [Homo sapiens] Length = 640 Score = 42.7 bits (99), Expect = 4e-04 Identities = 51/216 (23%), Positives = 90/216 (41%), Gaps = 25/216 (11%) Query: 1 MVEKYRPQTLNDLISHQDIL---STIQKFINEDRLPHLLLYGPPGTGKTSTILACAKQLY 57 + + RP TL D + + ++ + + +P L+L+GPPG GKT+ A Sbjct: 227 LADTMRPDTLQDYFGQSKAVGQDTLLRSLLETNEIPSLILWGPPGCGKTTLAHIIAS--- 283 Query: 58 KDKEFGSMVLELNASDDRGIDIIRGPILSFASTRTIFKKGFKLVILDEADAMTQDAQ-NA 116 K+ + L+A++ + D +R I + ++ FK+ ++ +DE + Q NA Sbjct: 284 NSKKHSIRFVTLSATNAKTND-VRDVIKQAQNEKSFFKRK-TILFIDEIHRFNKSQQVNA 341 Query: 117 --LRR----VIEKFTENTRFCLICNYLSKI-IPALQSRCTRFRFGPLTPELMVPRLEHVV 169 L R V+EK ++ ++ + I L S P + + Sbjct: 342 ALLSRCRVIVLEKLPVEAMVTILMRAINSLGIHVLDSS---------RPTDPLSHSSNSS 392 Query: 170 EEEKVDISEDGMKALVTLSSGDMRRALNILQSTNMA 205 E + I + + L LS GD R LN LQ +A Sbjct: 393 SEPAMFIEDKAVDTLAYLSDGDARAGLNGLQLAVLA 428 >gi|4502703 cell division cycle 6 protein [Homo sapiens] Length = 560 Score = 37.4 bits (85), Expect = 0.018 Identities = 55/219 (25%), Positives = 91/219 (41%), Gaps = 44/219 (20%) Query: 20 LSTIQKFINED----RLPHLLLYGPPGTGKTSTILACAKQLYKD-KEFGSMVL------- 67 + I+ F+ E + L L G PGTGKT+ + + L K+ K F +++L Sbjct: 179 MDVIRNFLREHICGKKAGSLYLSGAPGTGKTACLSRILQDLKKELKGFKTIMLNCMSLRT 238 Query: 68 -------------ELNASDDRGIDIIRGPILSFASTRTIFKKGFKLVILDEADAMTQDAQ 114 + S G D++R T K +++LDE D + Q Sbjct: 239 AQAVFPAIAQEICQEEVSRPAGKDMMR----KLEKHMTAEKGPMIVLVLDEMDQLDSKGQ 294 Query: 115 NALRRVIE-KFTENTRFCLI-----CNYLSKIIPALQSR--C--TRFRFGPLTPELMV-- 162 + L + E + N+ LI + +I+P LQ+R C F P T +V Sbjct: 295 DVLYTLFEWPWLSNSHLVLIGIANTLDLTDRILPRLQAREKCKPQLLNFPPYTRNQIVTI 354 Query: 163 --PRLEHVVEEEKVDISEDGMKA-LVTLSSGDMRRALNI 198 RL V ++ +D + A V+ SGD+R+AL++ Sbjct: 355 LQDRLNQVSRDQVLDNAAVQFCARKVSAVSGDVRKALDV 393 >gi|21361144 proteasome 26S ATPase subunit 3 [Homo sapiens] Length = 439 Score = 37.0 bits (84), Expect = 0.023 Identities = 26/77 (33%), Positives = 41/77 (53%), Gaps = 10/77 (12%) Query: 35 LLLYGPPGTGKTSTILACAKQLYKD--KEFGSMVLELNASDDRGIDIIRGPILSFASTRT 92 +L+YGPPGTGKT ACA Q K G ++++ D G ++R +FA + Sbjct: 223 VLMYGPPGTGKTLLARACAAQTKATFLKLAGPQLVQMFIGD--GAKLVRD---AFALAK- 276 Query: 93 IFKKGFKLVILDEADAM 109 +K ++ +DE DA+ Sbjct: 277 --EKAPSIIFIDELDAI 291 >gi|194018490 ATPase family, AAA domain containing 3C [Homo sapiens] Length = 411 Score = 37.0 bits (84), Expect = 0.023 Identities = 32/99 (32%), Positives = 48/99 (48%), Gaps = 12/99 (12%) Query: 34 HLLLYGPPGTGKTSTILACAKQLYKDKEFGSMVLELNASDDRGIDIIRGPILSFASTRTI 93 H+LLYGPPGTGK T+ A L+ ++ M A R + +A+T Sbjct: 172 HILLYGPPGTGK--TLFAKKLALHSGMDYAIMTGGDVAPMGREGVTAMHKLFDWANTS-- 227 Query: 94 FKKGFKLVILDEADAMTQDAQNALRRVIEKFTENTRFCL 132 ++G L+ +DEADA + +R EK +E+ R L Sbjct: 228 -RRGL-LLFVDEADAFLR------KRATEKISEDLRATL 258 >gi|26080431 ATPase family, AAA domain containing 5 [Homo sapiens] Length = 1844 Score = 36.2 bits (82), Expect = 0.040 Identities = 20/63 (31%), Positives = 32/63 (50%), Gaps = 6/63 (9%) Query: 35 LLLYGPPGTGKTSTILACAKQLYKDKEFGSMVLELNASDDRGIDIIRGPILSFASTRTIF 94 +L+ GP G GKT+ + ACA++L G + E+NAS R I + + + Sbjct: 1128 VLITGPTGVGKTAAVYACAQEL------GFKIFEVNASSQRSGRQILSQLKEATQSHQVD 1181 Query: 95 KKG 97 K+G Sbjct: 1182 KQG 1184 >gi|119964730 BCS1-like [Homo sapiens] Length = 419 Score = 35.4 bits (80), Expect = 0.068 Identities = 38/119 (31%), Positives = 58/119 (48%), Gaps = 32/119 (26%) Query: 6 RPQTLNDLISHQD----ILSTIQKFINEDR------LPH---LLLYGPPGTGKTSTILAC 52 R + LN ++ Q I+ +Q+FI+ + +P+ LLYGPPG GK+S I A Sbjct: 184 RRRPLNSVVLQQGLADRIVRDVQEFIDNPKWYTDRGIPYRRGYLLYGPPGCGKSSFITAL 243 Query: 53 AKQLYKDKEFGSMVLEL---NASDDRGIDIIRGPILSFASTRTIFKKGFKLVILDEADA 108 A +L E +L L + SDDR +LS A ++ LV+L++ DA Sbjct: 244 AGEL----EHSICLLSLTDSSLSDDR-----LNHLLSVAPQQS-------LVLLEDVDA 286 >gi|4757852 BCS1-like [Homo sapiens] Length = 419 Score = 35.4 bits (80), Expect = 0.068 Identities = 38/119 (31%), Positives = 58/119 (48%), Gaps = 32/119 (26%) Query: 6 RPQTLNDLISHQD----ILSTIQKFINEDR------LPH---LLLYGPPGTGKTSTILAC 52 R + LN ++ Q I+ +Q+FI+ + +P+ LLYGPPG GK+S I A Sbjct: 184 RRRPLNSVVLQQGLADRIVRDVQEFIDNPKWYTDRGIPYRRGYLLYGPPGCGKSSFITAL 243 Query: 53 AKQLYKDKEFGSMVLEL---NASDDRGIDIIRGPILSFASTRTIFKKGFKLVILDEADA 108 A +L E +L L + SDDR +LS A ++ LV+L++ DA Sbjct: 244 AGEL----EHSICLLSLTDSSLSDDR-----LNHLLSVAPQQS-------LVLLEDVDA 286 >gi|75677353 AAA-ATPase TOB3 [Homo sapiens] Length = 648 Score = 35.0 bits (79), Expect = 0.088 Identities = 30/96 (31%), Positives = 45/96 (46%), Gaps = 11/96 (11%) Query: 34 HLLLYGPPGTGKTSTILACAKQLYKDKEFGSMVLELNASDDRGIDIIRGPILSFASTRTI 93 H+LLYGPPGTGK T+ A L+ ++ M A R + +A+T Sbjct: 347 HILLYGPPGTGK--TLFAKKLALHSGMDYAIMTGGDVAPMGREGVTAMHKLFDWANTS-- 402 Query: 94 FKKGFKLVILDEADAM-----TQDAQNALRRVIEKF 124 ++G L+ +DEADA T++ LR + F Sbjct: 403 -RRGL-LLFMDEADAFLRKRATEEISKDLRATLNAF 436 >gi|31377667 peroxisomal LON protease-like [Homo sapiens] Length = 852 Score = 33.9 bits (76), Expect = 0.20 Identities = 43/171 (25%), Positives = 77/171 (45%), Gaps = 23/171 (13%) Query: 23 IQKFINEDRLPHLLLYGPPGTGKTSTILACAKQLYKDKEFGSMVL--ELNASDDRG---- 76 +++ N + P L GPPG GKTS + AK L +EF + L + SD RG Sbjct: 359 VRQLKNNLKGPILCFVGPPGVGKTSVGRSVAKTL--GREFHRIALGGVCDQSDIRGHRRT 416 Query: 77 -IDIIRGPILSFASTRTIFKKGFKLVILDEADAMTQDAQN----ALRRVIE-----KFTE 126 + + G I++ T + F +LDE D + + Q AL V++ FT+ Sbjct: 417 YVGSMPGRIINGLKTVGVNNPVF---LLDEVDKLGKSLQGDPAAALLEVLDPEQNHNFTD 473 Query: 127 NTRFCLICNYLSKIIPALQSRCTRFRFGPLTPELMVPRLEHVVEEEKVDIS 177 + + + LS+++ + T L + + ++ +EEK++I+ Sbjct: 474 H--YLNVAFDLSQVLFIATANTTATIPAALLDRMEIIQVPGYTQEEKIEIA 522 >gi|42476028 ATPase family, AAA domain containing 3A [Homo sapiens] Length = 634 Score = 33.9 bits (76), Expect = 0.20 Identities = 31/105 (29%), Positives = 49/105 (46%), Gaps = 12/105 (11%) Query: 28 NEDRLPHLLLYGPPGTGKTSTILACAKQLYKDKEFGSMVLELNASDDRGIDIIRGPILSF 87 N ++L+YGPPGTGK T+ A L+ ++ M A R + + Sbjct: 389 NRSLYRNILMYGPPGTGK--TLFAKKLALHSGMDYAIMTGGDVAPMGREGVTAMHKLFDW 446 Query: 88 ASTRTIFKKGFKLVILDEADAMTQDAQNALRRVIEKFTENTRFCL 132 A+T ++G L+ +DEADA + +R EK +E+ R L Sbjct: 447 ANTS---RRGL-LLFVDEADAFLR------KRATEKISEDLRATL 481 >gi|229577436 spermatogenesis associated 5-like 1 [Homo sapiens] Length = 753 Score = 33.5 bits (75), Expect = 0.26 Identities = 25/78 (32%), Positives = 37/78 (47%), Gaps = 9/78 (11%) Query: 35 LLLYGPPGTGKTSTILACAKQLYKDKEFGSMVLELNA---SDDRGIDIIRGPILSFASTR 91 +LL GPPG GKT + A A +E G+ +L ++A R + F R Sbjct: 237 VLLAGPPGVGKTQLVRAVA------REAGAELLAVSAPALQGSRPGETEENVRRVFQRAR 290 Query: 92 TIFKKGFKLVILDEADAM 109 + +G L+ LDE DA+ Sbjct: 291 ELASRGPSLLFLDEMDAL 308 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.322 0.137 0.389 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 10,801,330 Number of Sequences: 37866 Number of extensions: 433691 Number of successful extensions: 1293 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 45 Number of HSP's successfully gapped in prelim test: 31 Number of HSP's that attempted gapping in prelim test: 1207 Number of HSP's gapped (non-prelim): 96 length of query: 319 length of database: 18,247,518 effective HSP length: 102 effective length of query: 217 effective length of database: 14,385,186 effective search space: 3121585362 effective search space used: 3121585362 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.