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Search of human proteins with 194294554
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|194294554 SET binding protein 1 isoform a [Homo sapiens]
(1596 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|194294554 SET binding protein 1 isoform a [Homo sapiens] 3220 0.0
gi|110349788 absent, small, or homeotic 1-like [Homo sapiens] 468 e-131
gi|194294556 SET binding protein 1 isoform b [Homo sapiens] 360 6e-99
gi|52485606 formin-like 2 [Homo sapiens] 72 6e-12
gi|157168329 formin 1 [Homo sapiens] 67 2e-10
gi|47132519 Ras association and pleckstrin homology domains 1 is... 67 2e-10
gi|56549694 enabled homolog isoform a [Homo sapiens] 65 7e-10
gi|39930375 enabled homolog isoform b [Homo sapiens] 65 7e-10
gi|149999378 inverted formin 2 isoform 2 [Homo sapiens] 65 7e-10
gi|149999380 inverted formin 2 isoform 1 [Homo sapiens] 65 7e-10
gi|12597625 activating transcription factor 5 [Homo sapiens] 64 2e-09
gi|157817073 Cdc2-related kinase, arginine/serine-rich isoform 2... 64 2e-09
gi|157817023 Cdc2-related kinase, arginine/serine-rich isoform 1... 64 2e-09
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 62 3e-09
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 62 3e-09
gi|122937496 WAS/WASL interacting protein family, member 3 [Homo... 62 3e-09
gi|56549696 E1A binding protein p400 [Homo sapiens] 62 6e-09
gi|210032580 SET domain containing 1B [Homo sapiens] 62 6e-09
gi|153792074 proline rich 12 [Homo sapiens] 61 8e-09
gi|149944526 additional sex combs like 3 [Homo sapiens] 61 8e-09
gi|150378543 MYST histone acetyltransferase (monocytic leukemia)... 60 1e-08
gi|150378463 MYST histone acetyltransferase (monocytic leukemia)... 60 1e-08
gi|150378493 MYST histone acetyltransferase (monocytic leukemia)... 60 1e-08
gi|19923345 RNA binding motif protein 12 [Homo sapiens] 60 1e-08
gi|23510462 RNA binding motif protein 12 [Homo sapiens] 60 1e-08
gi|126090663 zinc finger homeodomain 4 [Homo sapiens] 60 2e-08
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa... 60 2e-08
gi|150170670 piccolo isoform 2 [Homo sapiens] 60 2e-08
gi|150378539 piccolo isoform 1 [Homo sapiens] 60 2e-08
gi|40807465 zinc finger protein 341 [Homo sapiens] 59 3e-08
>gi|194294554 SET binding protein 1 isoform a [Homo sapiens]
Length = 1596
Score = 3220 bits (8349), Expect = 0.0
Identities = 1596/1596 (100%), Positives = 1596/1596 (100%)
Query: 1 MESRETLSSSRQRGGESDFLPVSSAKPPAAPGCAGEPLLSTPGPGKGIPVGGERMEPEEE 60
MESRETLSSSRQRGGESDFLPVSSAKPPAAPGCAGEPLLSTPGPGKGIPVGGERMEPEEE
Sbjct: 1 MESRETLSSSRQRGGESDFLPVSSAKPPAAPGCAGEPLLSTPGPGKGIPVGGERMEPEEE 60
Query: 61 DELGSGRDVDSNSNADSEKWVAGDGLEEQEFSIKEANFTEGSLKLKIQTTKRAKKPPKNL 120
DELGSGRDVDSNSNADSEKWVAGDGLEEQEFSIKEANFTEGSLKLKIQTTKRAKKPPKNL
Sbjct: 61 DELGSGRDVDSNSNADSEKWVAGDGLEEQEFSIKEANFTEGSLKLKIQTTKRAKKPPKNL 120
Query: 121 ENYICPPEIKITIKQSGDQKVSRAGKNSKATKEEERSHSKKKLLTASDLAASDLKGFQPQ 180
ENYICPPEIKITIKQSGDQKVSRAGKNSKATKEEERSHSKKKLLTASDLAASDLKGFQPQ
Sbjct: 121 ENYICPPEIKITIKQSGDQKVSRAGKNSKATKEEERSHSKKKLLTASDLAASDLKGFQPQ 180
Query: 181 AYERPQKHSTLHYDTGLPQDFTGDTLKPKHQQKSSSQNHMDWSTNSDSGPVTQNCFISPE 240
AYERPQKHSTLHYDTGLPQDFTGDTLKPKHQQKSSSQNHMDWSTNSDSGPVTQNCFISPE
Sbjct: 181 AYERPQKHSTLHYDTGLPQDFTGDTLKPKHQQKSSSQNHMDWSTNSDSGPVTQNCFISPE 240
Query: 241 SGRETASTSKIPALEPVASFAKAQGKKGSAGNTWSQLSNNNKDLLLGGVAPSPSSHSSPA 300
SGRETASTSKIPALEPVASFAKAQGKKGSAGNTWSQLSNNNKDLLLGGVAPSPSSHSSPA
Sbjct: 241 SGRETASTSKIPALEPVASFAKAQGKKGSAGNTWSQLSNNNKDLLLGGVAPSPSSHSSPA 300
Query: 301 PPSSSAECNGLQPLVDQDGGGTKEPPEPPTVGSKKKSSKKDVISQTIPNPDLDWVKNAQK 360
PPSSSAECNGLQPLVDQDGGGTKEPPEPPTVGSKKKSSKKDVISQTIPNPDLDWVKNAQK
Sbjct: 301 PPSSSAECNGLQPLVDQDGGGTKEPPEPPTVGSKKKSSKKDVISQTIPNPDLDWVKNAQK 360
Query: 361 AFDNTEGKREGYSADSAQEASPARQNVSSASNPENDSSHVRITIPIKAPSLDPTNHKRKK 420
AFDNTEGKREGYSADSAQEASPARQNVSSASNPENDSSHVRITIPIKAPSLDPTNHKRKK
Sbjct: 361 AFDNTEGKREGYSADSAQEASPARQNVSSASNPENDSSHVRITIPIKAPSLDPTNHKRKK 420
Query: 421 RQSIKAVVEKIMPEKALASGITMSSEVVNRILSNSEGNKKDPRVPKLSKMIENESPSVGL 480
RQSIKAVVEKIMPEKALASGITMSSEVVNRILSNSEGNKKDPRVPKLSKMIENESPSVGL
Sbjct: 421 RQSIKAVVEKIMPEKALASGITMSSEVVNRILSNSEGNKKDPRVPKLSKMIENESPSVGL 480
Query: 481 ETGGNAEKVIPGGVSKPRKPPMVMTPPTCTDHSPSRKLPEIQHPKFAAKRRWTCSKPKPS 540
ETGGNAEKVIPGGVSKPRKPPMVMTPPTCTDHSPSRKLPEIQHPKFAAKRRWTCSKPKPS
Sbjct: 481 ETGGNAEKVIPGGVSKPRKPPMVMTPPTCTDHSPSRKLPEIQHPKFAAKRRWTCSKPKPS 540
Query: 541 TMLREAVMATSDKLMLEPPSAYPITPSSPLYTNTDSLTVITPVKKKRGRPKKQPLLTVET 600
TMLREAVMATSDKLMLEPPSAYPITPSSPLYTNTDSLTVITPVKKKRGRPKKQPLLTVET
Sbjct: 541 TMLREAVMATSDKLMLEPPSAYPITPSSPLYTNTDSLTVITPVKKKRGRPKKQPLLTVET 600
Query: 601 IHEGTSTSPVSPISREFPGTKKRKRRRNLAKLAQLVPGEDKPMSEMKFHKKVGKLGVLDK 660
IHEGTSTSPVSPISREFPGTKKRKRRRNLAKLAQLVPGEDKPMSEMKFHKKVGKLGVLDK
Sbjct: 601 IHEGTSTSPVSPISREFPGTKKRKRRRNLAKLAQLVPGEDKPMSEMKFHKKVGKLGVLDK 660
Query: 661 KTIKTINKMKTLKRKNILNQILSCSSSVALKAKAPPETSPGAAAIESKLGKQINVSKRGT 720
KTIKTINKMKTLKRKNILNQILSCSSSVALKAKAPPETSPGAAAIESKLGKQINVSKRGT
Sbjct: 661 KTIKTINKMKTLKRKNILNQILSCSSSVALKAKAPPETSPGAAAIESKLGKQINVSKRGT 720
Query: 721 IYIGKKRGRKPRAELPPPSEEPKTAIKHPRPVSSQPDVPAVPSNFQSLVASSPAAMHPLS 780
IYIGKKRGRKPRAELPPPSEEPKTAIKHPRPVSSQPDVPAVPSNFQSLVASSPAAMHPLS
Sbjct: 721 IYIGKKRGRKPRAELPPPSEEPKTAIKHPRPVSSQPDVPAVPSNFQSLVASSPAAMHPLS 780
Query: 781 TQLGGSNGNLSPASTETNFSELKTMPNLQPISALPTKTQKGIHSGTWKLSPPRLMANSPS 840
TQLGGSNGNLSPASTETNFSELKTMPNLQPISALPTKTQKGIHSGTWKLSPPRLMANSPS
Sbjct: 781 TQLGGSNGNLSPASTETNFSELKTMPNLQPISALPTKTQKGIHSGTWKLSPPRLMANSPS 840
Query: 841 HLCEIGSLKEITLSPVSESHSEETIPSDSGIGTDNNSTSDQAEKSSESRRRYSFDFCSLD 900
HLCEIGSLKEITLSPVSESHSEETIPSDSGIGTDNNSTSDQAEKSSESRRRYSFDFCSLD
Sbjct: 841 HLCEIGSLKEITLSPVSESHSEETIPSDSGIGTDNNSTSDQAEKSSESRRRYSFDFCSLD 900
Query: 901 NPEAIPSDTSTKNRHGHRQKHLIVDNFLAHESLKKPKHKRKRKSLQNRDDLQFLADLEEL 960
NPEAIPSDTSTKNRHGHRQKHLIVDNFLAHESLKKPKHKRKRKSLQNRDDLQFLADLEEL
Sbjct: 901 NPEAIPSDTSTKNRHGHRQKHLIVDNFLAHESLKKPKHKRKRKSLQNRDDLQFLADLEEL 960
Query: 961 ITKFQVFRISHRSYTFYHENPYPSIFRINFDHYYPVPYIQYDPLLYLRRTSDLKSKKKRG 1020
ITKFQVFRISHRSYTFYHENPYPSIFRINFDHYYPVPYIQYDPLLYLRRTSDLKSKKKRG
Sbjct: 961 ITKFQVFRISHRSYTFYHENPYPSIFRINFDHYYPVPYIQYDPLLYLRRTSDLKSKKKRG 1020
Query: 1021 RPAKTNDTMTKVPFLQGFSYPIPSGSYYAPYGMPYTSMPMMNLGYYGQYPAPLYLSHTLG 1080
RPAKTNDTMTKVPFLQGFSYPIPSGSYYAPYGMPYTSMPMMNLGYYGQYPAPLYLSHTLG
Sbjct: 1021 RPAKTNDTMTKVPFLQGFSYPIPSGSYYAPYGMPYTSMPMMNLGYYGQYPAPLYLSHTLG 1080
Query: 1081 AASPFMRPTVPPPQFHTNSHVKMSGAAKHKAKHGVHLQGPVSMGLGDMQPSLNPPKVGSA 1140
AASPFMRPTVPPPQFHTNSHVKMSGAAKHKAKHGVHLQGPVSMGLGDMQPSLNPPKVGSA
Sbjct: 1081 AASPFMRPTVPPPQFHTNSHVKMSGAAKHKAKHGVHLQGPVSMGLGDMQPSLNPPKVGSA 1140
Query: 1141 SLSSGRLHKRKHKHKHKHKEDRILGTHDNLSGLFAGKATGFSSHILSERLSSADKELPLV 1200
SLSSGRLHKRKHKHKHKHKEDRILGTHDNLSGLFAGKATGFSSHILSERLSSADKELPLV
Sbjct: 1141 SLSSGRLHKRKHKHKHKHKEDRILGTHDNLSGLFAGKATGFSSHILSERLSSADKELPLV 1200
Query: 1201 SEKNKHKEKQKHQHSEAGHKASKNNFEVDTLSTLSLSDAQHWTQAKEKGDLSSEPVDSCT 1260
SEKNKHKEKQKHQHSEAGHKASKNNFEVDTLSTLSLSDAQHWTQAKEKGDLSSEPVDSCT
Sbjct: 1201 SEKNKHKEKQKHQHSEAGHKASKNNFEVDTLSTLSLSDAQHWTQAKEKGDLSSEPVDSCT 1260
Query: 1261 KRYSGSGGDGGSTRSENLDVFSEMNPSNDKWDSDVSGSKRRSYEGFGTYREKDIQAFKMN 1320
KRYSGSGGDGGSTRSENLDVFSEMNPSNDKWDSDVSGSKRRSYEGFGTYREKDIQAFKMN
Sbjct: 1261 KRYSGSGGDGGSTRSENLDVFSEMNPSNDKWDSDVSGSKRRSYEGFGTYREKDIQAFKMN 1320
Query: 1321 RKERSSYDSSMSPGMPSPHLKVDQTAVHSKNEGSVPTMMTRKKPAAVDSVTIPPAPVLSL 1380
RKERSSYDSSMSPGMPSPHLKVDQTAVHSKNEGSVPTMMTRKKPAAVDSVTIPPAPVLSL
Sbjct: 1321 RKERSSYDSSMSPGMPSPHLKVDQTAVHSKNEGSVPTMMTRKKPAAVDSVTIPPAPVLSL 1380
Query: 1381 LAASAATSDAVGSSLKKRFKRREIEAIQCEVRKMCNYTKILSTKKNLDHVNKILKAKRLQ 1440
LAASAATSDAVGSSLKKRFKRREIEAIQCEVRKMCNYTKILSTKKNLDHVNKILKAKRLQ
Sbjct: 1381 LAASAATSDAVGSSLKKRFKRREIEAIQCEVRKMCNYTKILSTKKNLDHVNKILKAKRLQ 1440
Query: 1441 RQSKTGNNFVKKRRGRPRKQPTQFDEDSRDQMPVLEKCIDLPSKRGQKPSLSPLVLEPAA 1500
RQSKTGNNFVKKRRGRPRKQPTQFDEDSRDQMPVLEKCIDLPSKRGQKPSLSPLVLEPAA
Sbjct: 1441 RQSKTGNNFVKKRRGRPRKQPTQFDEDSRDQMPVLEKCIDLPSKRGQKPSLSPLVLEPAA 1500
Query: 1501 SQDTIMATIEAVIHMAREAPPLPPPPPPPLPPPPPPPLPPPPPLPKTPRGGKRKHKPQAP 1560
SQDTIMATIEAVIHMAREAPPLPPPPPPPLPPPPPPPLPPPPPLPKTPRGGKRKHKPQAP
Sbjct: 1501 SQDTIMATIEAVIHMAREAPPLPPPPPPPLPPPPPPPLPPPPPLPKTPRGGKRKHKPQAP 1560
Query: 1561 AQPPQQSPPQQPLPQEEEVKAKRQRKSRGSESEVLP 1596
AQPPQQSPPQQPLPQEEEVKAKRQRKSRGSESEVLP
Sbjct: 1561 AQPPQQSPPQQPLPQEEEVKAKRQRKSRGSESEVLP 1596
>gi|110349788 absent, small, or homeotic 1-like [Homo sapiens]
Length = 2964
Score = 468 bits (1204), Expect = e-131
Identities = 402/1243 (32%), Positives = 574/1243 (46%), Gaps = 168/1243 (13%)
Query: 463 RVPKLSKMIENESPSVGLETGGNAEKVIPGGVSKPRKPPMVMTPPTCTDHSPSRKLPEIQ 522
R+PKLSK + +PS+ L K V + + P R P+ +
Sbjct: 778 RLPKLSK---STAPSLALLADSEKPSHKSFATHKLSSSMCVSSDLLSDIYKPKRGRPKSK 834
Query: 523 H-PKFAAKRRWTCSKPKPSTMLREAVMATSDKLMLEPPSAYPITPSSPLYTNTDSLTVIT 581
P+ + T P V + K EPP + P + + L+V +
Sbjct: 835 EMPQLEGPPKRTLKIPASK------VFSLQSKEEQEPPI---LQPEIEIPSFKQGLSV-S 884
Query: 582 PVKKKRGRPKKQPLLTVETIHEGTSTSPV----SPISREFPGTKKRKRRRNLAKLAQLVP 637
P KKRGRPK+Q V+ S +P SP E R QL
Sbjct: 885 PFPKKRGRPKRQMRSPVKMKPPVLSVAPFVATESPSKLESESDNHRSSSDFFESEDQLQD 944
Query: 638 GEDKPMS-----------EMKFHKKVGKL--GVLDKKTIKTINKMKTLKRKNILNQILSC 684
+D S EM+ KK+ K G L K I+ INKMKTLKRK +LNQILS
Sbjct: 945 PDDLDDSHRPSVCSMSDLEMEPDKKITKRNNGQLMKTIIRKINKMKTLKRKKLLNQILSS 1004
Query: 685 SSSVALKAKAPPE----TSPGAAAIESKLGKQINVSKRGTIYIGKKRGRKPRAELPPPSE 740
S + K K + S AA SKLG+QINVSK+GTIYIGK+RGRKP+ L
Sbjct: 1005 SVESSNKGKVQSKLHNTVSSLAATFGSKLGQQINVSKKGTIYIGKRRGRKPKTVLNGILS 1064
Query: 741 EPKTAIKHPRPVSSQPDVPAV----PSNFQSLVASSPAAMHPLSTQLGGSNGNLSPASTE 796
T++ + Q A+ P S +SS P+ +Q G++G SP S++
Sbjct: 1065 GSPTSLAVLEQTAQQAAGSALGQILPPLLPSSASSSEILPSPICSQSSGTSGGQSPVSSD 1124
Query: 797 TNFSELKTMPNL----QPISALPTKTQKGIHSGTWKLSPPRLMANSPSHLCEIGSLKEIT 852
F E ++P L + S + T K G +LSPP L+ NSPSHL E+ SLKE T
Sbjct: 1125 AGFVEPSSVPYLHLHSRQGSMIQTLAMKKASKGRRRLSPPTLLPNSPSHLSELTSLKEAT 1184
Query: 853 LSPVSESHSEETIPSDSGIGTDNNSTSDQAEK-SSESRRRYSFDFCSLDNPEAIPSDTST 911
SP+SESHS+ETIPSDSGIGTDNNSTSD+AEK + +RR+SF+ SL PE +S
Sbjct: 1185 PSPISESHSDETIPSDSGIGTDNNSTSDRAEKFCGQKKRRHSFEHVSLIPPETSTVLSSL 1244
Query: 912 KNRHGHRQKHLIVDNFLAHESLKKPKHKRKRK--SLQNRDDLQFLADLEELITKFQVFRI 969
K +H H+ K D +L+++ +K+ K KRK+K L+NR D F+A+LEELI++ RI
Sbjct: 1245 KEKHKHKCKRRNHD-YLSYDKMKRQKRKRKKKYPQLRNRQDPDFIAELEELISRLSEIRI 1303
Query: 970 SHRSYTFYHENPYPSIFRINFDHYYPVPYIQYDPLLYLRRTSDLKSKKKRGRPAKTNDTM 1029
+HRS+ F + P+IFRINF+ +Y P DPL Y+R+ DLK KKRGRP K + M
Sbjct: 1304 THRSHHFIPRDLLPTIFRINFNSFYTHPSFPLDPLHYIRKP-DLK--KKRGRPPKMREAM 1360
Query: 1030 TKVPFLQGFSYPIPSGSYYAPYGMPYTSMPM----MNLGYYGQYPAPLYLSHTLGAASPF 1085
++PF+ S+P+ S +Y YGMPY+ P+ + LGYYG+YP LY SP
Sbjct: 1361 AEMPFMHSLSFPLSSTGFYPSYGMPYSPSPLTAAPIGLGYYGRYPPTLYPP----PPSPS 1416
Query: 1086 MRPTVPPPQFHTNSHVKMSGAAKHKAKHGVHLQGPVSMGLGDMQPSLNPPKVGSASLSSG 1145
+PPP + H+ ++ A HK KH + Q S++ ++ G
Sbjct: 1417 FTTPLPPPSYMHAGHLLLNPAKYHKKKHKLLRQEAFLTTSRTPLLSMSTYPSVPPEMAYG 1476
Query: 1146 RLHKRKHKHKHKHKEDRI-------LGTHDNLSGLFAGKATGFSSHILSERLSSADKEL- 1197
+ + KH+H+HKH+E R + T + S L + K F + ER +K
Sbjct: 1477 WMVEHKHRHRHKHREHRSSEQPQVSMDTGSSRSVLESLKRYRFGKDAVGERYKHKEKHRC 1536
Query: 1198 --------PLVSEKNKHKEKQKHQHSEAGHKAS--KNNFEVD------TLSTLSLSDAQH 1241
P S N+ ++ + SE+ A + ++D +LS +
Sbjct: 1537 HMSCPHLSPSKSLINREEQWVHREPSESSPLALGLQTPLQIDCSESSPSLSLGGFTPNSE 1596
Query: 1242 WTQAKEKGDLSSEPVDSCTKRYSGSGGDGGSTRSENLDVFS------------EMNPSND 1289
+ E +L + + SC R S G +++ +FS E PSN+
Sbjct: 1597 PASSDEHTNLFTSAIGSC--RVSNPNSSGRKKLTDSPGLFSAQDTSLNRLHRKESLPSNE 1654
Query: 1290 KWDSDVSGSKRRSYEGFGTYREKDIQAFKMNRKERSSYDSSMSP-GMPSPHLKVDQTAVH 1348
+ ++GS+ S + + R + RK SS +S + G+PS ++ +
Sbjct: 1655 RAVQTLAGSQPTSDKP--SQRPSESTNCSPTRKRSSSESTSSTVNGVPSRSPRLVASGDD 1712
Query: 1349 S---------KNEGSVPTMMTRKKPAAVDSVTIPPA--PVLS-----------LLAASAA 1386
S +NE P M + A + + + PP+ P S L A
Sbjct: 1713 SVDSLLQRMVQNEDQEP--MEKSIDAVIATASAPPSSSPGRSHSKDRTLGKPDSLLVPAV 1770
Query: 1387 TSDAVGSSLK------------KRFKRREIEAIQCEVRKMCNYTKILSTKKNLDHVNKIL 1434
TSD+ +S+ KR +EA+Q + RKMCNY KIL+TKKNLDHVNKIL
Sbjct: 1771 TSDSCNNSISLLSEKLTSSCSPHHIKRSVVEAMQRQARKMCNYDKILATKKNLDHVNKIL 1830
Query: 1435 KAKRLQRQSKTGNNFVKKRRGRPRKQPTQFDEDSRDQMPVLEKCIDLPSKRGQKPSLSPL 1494
KAK+LQRQ++TGNNFVK+R GRPRK P Q + M + + + + + L
Sbjct: 1831 KAKKLQRQARTGNNFVKRRPGRPRKCPLQ----AVVSMQAFQAAQFVNPELNRDEEGAAL 1886
Query: 1495 VLEPAASQDTIMATIEAVIHMAREAP--------------PLPPPPPPPLPP-------- 1532
L P DT+ IEAV+ P PLP
Sbjct: 1887 HLSP----DTVTDVIEAVVQSVNLNPEHKKGLKRKGWLLEEQTRKKQKPLPEEEEQENNK 1942
Query: 1533 ---PPPPPLPPPPPLPKTPRGGKRKHKPQAPAQPPQQSPPQQP 1572
P +P P P P + +P P ++ PP+ P
Sbjct: 1943 SFNEAPVEIPSPSETPAKPSEPESTLQPVLSLIPREKKPPRPP 1985
Score = 82.4 bits (202), Expect = 3e-15
Identities = 89/295 (30%), Positives = 127/295 (43%), Gaps = 35/295 (11%)
Query: 53 ERMEPEEEDELGSGRDVDSNSNADSEKWVAGDGLEE--QEFSIKEANFTEGSLKLKIQT- 109
E+ EEED R+ + + D DGL + Q+FS+KE NF+EG+LKLKI
Sbjct: 40 EKNTKEEEDLRKRNRERNIEAGKD-------DGLTDAQQQFSVKETNFSEGNLKLKIGLQ 92
Query: 110 TKRAKKPPKNLENYICPPEIKITIKQSGDQKVSRAGKNSKATKEEERSHSKKKLLTASDL 169
KR KKPPKNLENY+C P IK TIK +A K+ K T E+ K+ +
Sbjct: 93 AKRTKKPPKNLENYVCRPAIKTTIKHP-----RKALKSGKMTDEKNEHCPSKRDPSKLYK 147
Query: 170 AASDLKGFQPQAYERPQKHSTLHYDTGLPQDFTGDTLKPKHQQKSSSQNHMDWSTNSDSG 229
A D+ + Q+ E + HS + L P H + + N +
Sbjct: 148 KADDVAAIECQSEEVIRLHSQGENNP------LSKKLSPVHSEMADYINATPSTLLGSRD 201
Query: 230 PVTQNCFISPESGRETASTSKIPALEPVASFAKAQGKKGSAGNTWSQLSNNNKDLL---- 285
P ++ + T +++ A P + +K + KK G T +S KDL+
Sbjct: 202 PDLKDRALLNGGTSVTEKLAQLIATCPPSKSSKTKPKKLGTGTTAGLVS---KDLIRKAG 258
Query: 286 LGGVAPSPSSHSSPAPPSSSAECNGLQPLVDQDGGGTKEPPEPPTVGSKKKSSKK 340
+G VA P S+A LV +D G K+P VG K S K
Sbjct: 259 VGSVAGIIHKDLIKKPTISTA-----VGLVTKDPG--KKPVFNAAVGLVNKDSVK 306
>gi|194294556 SET binding protein 1 isoform b [Homo sapiens]
Length = 242
Score = 360 bits (924), Expect = 6e-99
Identities = 180/180 (100%), Positives = 180/180 (100%)
Query: 1 MESRETLSSSRQRGGESDFLPVSSAKPPAAPGCAGEPLLSTPGPGKGIPVGGERMEPEEE 60
MESRETLSSSRQRGGESDFLPVSSAKPPAAPGCAGEPLLSTPGPGKGIPVGGERMEPEEE
Sbjct: 1 MESRETLSSSRQRGGESDFLPVSSAKPPAAPGCAGEPLLSTPGPGKGIPVGGERMEPEEE 60
Query: 61 DELGSGRDVDSNSNADSEKWVAGDGLEEQEFSIKEANFTEGSLKLKIQTTKRAKKPPKNL 120
DELGSGRDVDSNSNADSEKWVAGDGLEEQEFSIKEANFTEGSLKLKIQTTKRAKKPPKNL
Sbjct: 61 DELGSGRDVDSNSNADSEKWVAGDGLEEQEFSIKEANFTEGSLKLKIQTTKRAKKPPKNL 120
Query: 121 ENYICPPEIKITIKQSGDQKVSRAGKNSKATKEEERSHSKKKLLTASDLAASDLKGFQPQ 180
ENYICPPEIKITIKQSGDQKVSRAGKNSKATKEEERSHSKKKLLTASDLAASDLKGFQPQ
Sbjct: 121 ENYICPPEIKITIKQSGDQKVSRAGKNSKATKEEERSHSKKKLLTASDLAASDLKGFQPQ 180
>gi|52485606 formin-like 2 [Homo sapiens]
Length = 1092
Score = 71.6 bits (174), Expect = 6e-12
Identities = 33/55 (60%), Positives = 35/55 (63%), Gaps = 6/55 (10%)
Query: 1520 PPLPPPPPPPLPPPPPPPLPPPPPLPKTPRGGKRKHKPQAPAQPPQQSPPQQPLP 1574
PP+PPPPPPP PPPPPPP PPPPPLP G + P P PP S P PLP
Sbjct: 550 PPMPPPPPPPPPPPPPPPPPPPPPLP----GPAAETVPAPPLAPPLPSAP--PLP 598
Score = 55.5 bits (132), Expect = 4e-07
Identities = 25/49 (51%), Positives = 25/49 (51%)
Query: 1520 PPLPPPPPPPLPPPPPPPLPPPPPLPKTPRGGKRKHKPQAPAQPPQQSP 1568
PP PPPPPPP PPPPPPP P P P P AP P SP
Sbjct: 555 PPPPPPPPPPPPPPPPPPPLPGPAAETVPAPPLAPPLPSAPPLPGTSSP 603
>gi|157168329 formin 1 [Homo sapiens]
Length = 1196
Score = 66.6 bits (161), Expect = 2e-10
Identities = 46/145 (31%), Positives = 61/145 (42%), Gaps = 10/145 (6%)
Query: 1437 KRLQRQSKT--GNNFVKKRRGRPRKQPTQFDEDSRDQMPVLEKCIDLPSKRGQKPSLSPL 1494
K + +SKT N V K+ D +D L+ + S + + P
Sbjct: 591 KPCESESKTTRSNQLVPKKLNISSLSQLSPPNDHKDIHAALQPMEGMASNQQKALPPPPA 650
Query: 1495 VLEPAASQDTIMATIEAVIHM--AREAPPLPPPPPPPLPPPPP-----PPLPPPPPLPKT 1547
+ P + + ++ M PPLPPPPPPP P PPP PP PPPPPLP +
Sbjct: 651 SIPPPPPLPSGLGSLSPAPPMPPVSAGPPLPPPPPPPPPLPPPSSAGPPPPPPPPPLPNS 710
Query: 1548 PRGGKRKHKPQAPAQPPQQSPPQQP 1572
P P AP PP +PP P
Sbjct: 711 PAPPNPGGPPPAP-PPPGLAPPPPP 734
Score = 50.1 bits (118), Expect = 2e-05
Identities = 37/104 (35%), Positives = 43/104 (41%), Gaps = 30/104 (28%)
Query: 1496 LEPAASQDTIMATIEAVIHMA---REAPPLPP---PPPPPLP------------------ 1531
L P I A ++ + MA ++A P PP PPPPPLP
Sbjct: 618 LSPPNDHKDIHAALQPMEGMASNQQKALPPPPASIPPPPPLPSGLGSLSPAPPMPPVSAG 677
Query: 1532 -PPPPPPLPPPPPLPKTPRGGKRKHKPQAPAQPPQQSPPQQPLP 1574
P PPPP PPPPPLP G P P PP + P P P
Sbjct: 678 PPLPPPP-PPPPPLPPPSSAG----PPPPPPPPPLPNSPAPPNP 716
Score = 44.7 bits (104), Expect = 7e-04
Identities = 27/64 (42%), Positives = 30/64 (46%), Gaps = 10/64 (15%)
Query: 1520 PPLPPPPP------PPLPPPPPPPLPPPPPLPKTPRG---GKRKHKPQAPAQPP-QQSPP 1569
PP PPPPP PP P PPP PPP P P G G Q P +P + S P
Sbjct: 699 PPPPPPPPLPNSPAPPNPGGPPPAPPPPGLAPPPPPGLFFGLGSSSSQCPRKPAIEPSCP 758
Query: 1570 QQPL 1573
+PL
Sbjct: 759 MKPL 762
>gi|47132519 Ras association and pleckstrin homology domains 1 isoform
1 [Homo sapiens]
Length = 1250
Score = 66.6 bits (161), Expect = 2e-10
Identities = 47/135 (34%), Positives = 63/135 (46%), Gaps = 31/135 (22%)
Query: 1459 KQPTQFDEDSRDQMPVLEKCIDLPSKRGQKPSLSPLVLEPAASQDTIMATIEAVIHMARE 1518
K+ TQ +E S+ +M + + P S ++ P + Q I+ A ++
Sbjct: 582 KRGTQLEESSKARMESMNR-----------PYTS--LVPPLSPQPKIVTPYTA----SQP 624
Query: 1519 APPLPPPPPPPLPPPPPPPLPPPPPLP--KTPRGGKR-----KHKPQAPAQPPQQ----- 1566
+PPLPPPPPPP PPPPPPP PPPPPLP P G K+ Q Q
Sbjct: 625 SPPLPPPPPPP-PPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGAL 683
Query: 1567 -SPPQQPLPQEEEVK 1580
PP P+ Q + VK
Sbjct: 684 FKPPTPPVMQSQSVK 698
Score = 53.5 bits (127), Expect = 2e-06
Identities = 36/99 (36%), Positives = 41/99 (41%), Gaps = 26/99 (26%)
Query: 1509 IEAVIHMAREAPPLPPPPPP---PLPPPPPP------PLP--------------PPPPLP 1545
I V H+ + APP PPPPPP PLPP PP P P PP P P
Sbjct: 749 IHQVQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTP 808
Query: 1546 KTPRGGKRKHKPQAPAQPPQQSPPQQPLPQEEEVKAKRQ 1584
P K +P PA SPP P+P K+Q
Sbjct: 809 PVP---PAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQ 844
Score = 50.8 bits (120), Expect = 1e-05
Identities = 24/59 (40%), Positives = 27/59 (45%), Gaps = 6/59 (10%)
Query: 1520 PPLPP------PPPPPLPPPPPPPLPPPPPLPKTPRGGKRKHKPQAPAQPPQQSPPQQP 1572
PP PP PPPPP P P PPP PPP P + G K + P + PP P
Sbjct: 917 PPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTP 975
Score = 47.4 bits (111), Expect = 1e-04
Identities = 34/107 (31%), Positives = 42/107 (39%), Gaps = 25/107 (23%)
Query: 1493 PLVLEPAASQDTIMATIEAVIHMAREAPPLPP------------PPPPPLP--PPPPPPL 1538
PLV PA + +A + PP+PP PP PP P P PPP L
Sbjct: 781 PLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTL 840
Query: 1539 ---------PPPPPLPKTPRGGKR--KHKPQAPAQPPQQSPPQQPLP 1574
PPP PL P K+ P P P +S P +P+P
Sbjct: 841 PKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVP 887
Score = 44.7 bits (104), Expect = 7e-04
Identities = 21/50 (42%), Positives = 26/50 (52%), Gaps = 1/50 (2%)
Query: 1523 PPPPPPPLP-PPPPPPLPPPPPLPKTPRGGKRKHKPQAPAQPPQQSPPQQ 1571
PPPPP P+P PPPPPP P K+ GK+ K +P PQ+
Sbjct: 928 PPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQR 977
Score = 43.9 bits (102), Expect = 0.001
Identities = 25/65 (38%), Positives = 26/65 (40%), Gaps = 17/65 (26%)
Query: 1520 PPLPPPPP---PPLPPPPPPPLPPPPPLPKTPRGGKRKHKPQAPAQPPQQSPPQQPLPQE 1576
PPL P P P P PPLPPPPP P P PP PP PLP +
Sbjct: 607 PPLSPQPKIVTPYTASQPSPPLPPPPPPP--------------PPPPPPPPPPPPPLPSQ 652
Query: 1577 EEVKA 1581
A
Sbjct: 653 SAPSA 657
Score = 43.9 bits (102), Expect = 0.001
Identities = 30/99 (30%), Positives = 41/99 (41%), Gaps = 16/99 (16%)
Query: 1492 SPLVLEPAASQDTIMATIEAVIHMAREAPPLPPPPPPPLPPPPPPPLPPPPPLPKTPRGG 1551
+P V++ + + I+ V+ PP PPPPPPP P L P P P P+
Sbjct: 688 TPPVMQSQSVKPQILVPPNGVV------PPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFS 741
Query: 1552 K-----RKHKPQ-----APAQPPQQSPPQQPLPQEEEVK 1580
+ H+ Q AP PP P PLP + K
Sbjct: 742 APPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPK 780
Score = 43.1 bits (100), Expect = 0.002
Identities = 39/145 (26%), Positives = 51/145 (35%), Gaps = 29/145 (20%)
Query: 1457 PRKQPTQFDEDSRDQMPVLEKCIDLPSKRGQKPSLSPLVLEPAASQDTIMATIEAVIHMA 1516
P PT + S P +PS Q S P P A + + + A ++A
Sbjct: 834 PVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPA--NVA 891
Query: 1517 REAPPLP-----------PPPPPPLPPPPPPP---LPPPPPLPKTPRGGKRKHKPQAPAQ 1562
++PP P P P PPPPP PPPPP P PA
Sbjct: 892 PQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSP-------------VPAP 938
Query: 1563 PPQQSPPQQPLPQEEEVKAKRQRKS 1587
PP P P P + K+ K+
Sbjct: 939 PPPPPPTASPTPDKSGSPGKKTSKT 963
Score = 38.5 bits (88), Expect = 0.053
Identities = 24/80 (30%), Positives = 32/80 (40%), Gaps = 7/80 (8%)
Query: 1520 PPLPPPPPPPLPPPPPPPLPPPPPLP-------KTPRGGKRKHKPQAPAQPPQQSPPQQP 1572
PP P P PPP PPP P P P +P G K PQ + S + P
Sbjct: 931 PPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHP 990
Query: 1573 LPQEEEVKAKRQRKSRGSES 1592
P+ V + + + +ES
Sbjct: 991 EPKRPSVDSLVSKFTPPAES 1010
Score = 31.6 bits (70), Expect = 6.4
Identities = 30/116 (25%), Positives = 43/116 (37%), Gaps = 4/116 (3%)
Query: 1482 PSKRGQKPSLSPLVLEPAASQDTIMATIEAVIHMAREAPPLPPPPPPPLPPPPPPP---L 1538
P K G K +LS + L Q + A + +++ P PP PPPPP L
Sbjct: 1024 PPKPG-KLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPETEL 1082
Query: 1539 PPPPPLPKTPRGGKRKHKPQAPAQPPQQSPPQQPLPQEEEVKAKRQRKSRGSESEV 1594
P PP G K PQQ + KR +R +++E+
Sbjct: 1083 PLPPIEIPAVFSGNTSPKVAVVNPQPQQWSKMSVKKAPPPTRPKRNDSTRLTQAEI 1138
>gi|56549694 enabled homolog isoform a [Homo sapiens]
Length = 591
Score = 64.7 bits (156), Expect = 7e-10
Identities = 50/203 (24%), Positives = 90/203 (44%), Gaps = 38/203 (18%)
Query: 1396 KKRFKRREIEAIQCEVRKMCNYTKILSTKKNLDHVNKILKAKRLQRQSKTGNNFVKKRRG 1455
++R +R +E + E ++ + ++ L+ ++ + +RL+RQ + ++R+
Sbjct: 173 RERLERERLERERLEQEQLERERQERERQERLERQERLERQERLERQERLDRER-QERQE 231
Query: 1456 RPRKQPTQFDEDSRDQMPVLEK-CIDLPSKRGQKPSLSPLVLEP---------AASQDTI 1505
R R + + + R++ LE+ ++ +R + +P +E +AS+ +
Sbjct: 232 RERLERLERERQERERQEQLEREQLEWERERRISSAAAPASVETPLNSVLGDSSASEPGL 291
Query: 1506 MATIEAVIHMAREA---PPLPPPPPPPLPP---------PPPPPLPPPPPLPKTPRGGKR 1553
A + +++ PL PPPPPPLPP PPPP PPPPPLP T
Sbjct: 292 QAASQPAETPSQQGIVLGPLAPPPPPPLPPGPAQASVALPPPPGPPPPPPLPSTG----- 346
Query: 1554 KHKPQAPAQPPQQSPPQQPLPQE 1576
P PP PLP +
Sbjct: 347 ----------PPPPPPPPPLPNQ 359
Score = 50.4 bits (119), Expect = 1e-05
Identities = 21/27 (77%), Positives = 21/27 (77%), Gaps = 2/27 (7%)
Query: 1521 PLPPPPPPPLP--PPPPPPLPPPPPLP 1545
P PPPPPPPLP PPPPP PP PPLP
Sbjct: 347 PPPPPPPPPLPNQVPPPPPPPPAPPLP 373
>gi|39930375 enabled homolog isoform b [Homo sapiens]
Length = 570
Score = 64.7 bits (156), Expect = 7e-10
Identities = 50/203 (24%), Positives = 90/203 (44%), Gaps = 38/203 (18%)
Query: 1396 KKRFKRREIEAIQCEVRKMCNYTKILSTKKNLDHVNKILKAKRLQRQSKTGNNFVKKRRG 1455
++R +R +E + E ++ + ++ L+ ++ + +RL+RQ + ++R+
Sbjct: 173 RERLERERLERERLEQEQLERERQERERQERLERQERLERQERLERQERLDRER-QERQE 231
Query: 1456 RPRKQPTQFDEDSRDQMPVLEK-CIDLPSKRGQKPSLSPLVLEP---------AASQDTI 1505
R R + + + R++ LE+ ++ +R + +P +E +AS+ +
Sbjct: 232 RERLERLERERQERERQEQLEREQLEWERERRISSAAAPASVETPLNSVLGDSSASEPGL 291
Query: 1506 MATIEAVIHMAREA---PPLPPPPPPPLPP---------PPPPPLPPPPPLPKTPRGGKR 1553
A + +++ PL PPPPPPLPP PPPP PPPPPLP T
Sbjct: 292 QAASQPAETPSQQGIVLGPLAPPPPPPLPPGPAQASVALPPPPGPPPPPPLPSTG----- 346
Query: 1554 KHKPQAPAQPPQQSPPQQPLPQE 1576
P PP PLP +
Sbjct: 347 ----------PPPPPPPPPLPNQ 359
Score = 50.4 bits (119), Expect = 1e-05
Identities = 21/27 (77%), Positives = 21/27 (77%), Gaps = 2/27 (7%)
Query: 1521 PLPPPPPPPLP--PPPPPPLPPPPPLP 1545
P PPPPPPPLP PPPPP PP PPLP
Sbjct: 347 PPPPPPPPPLPNQVPPPPPPPPAPPLP 373
>gi|149999378 inverted formin 2 isoform 2 [Homo sapiens]
Length = 1240
Score = 64.7 bits (156), Expect = 7e-10
Identities = 45/138 (32%), Positives = 57/138 (41%), Gaps = 22/138 (15%)
Query: 1454 RGRPRKQP---------TQFDEDSRDQMPVLEKCIDLPSKRGQKPSLSPLVLEPAASQDT 1504
+GRPR P D+ R P PS GQ+P+ + +Q
Sbjct: 345 KGRPRPSPLVKAHKSVQANLDQSQRGSSPQ-NTTTPKPSVEGQQPAAAAACEPVDHAQSE 403
Query: 1505 IMATIEAVIHMAREAPPLPPPPPPPLPP---PPPPPLPPPPPLPKTPRGGKRKHKPQAPA 1561
+ + + ++A PPPPPPPL P PPP PPPPPLP K P AP
Sbjct: 404 SILKVSQPRALEQQASTPPPPPPPPLLPGSSAEPPPPPPPPPLPSV----GAKALPTAPP 459
Query: 1562 QPP-----QQSPPQQPLP 1574
PP +PP PLP
Sbjct: 460 PPPLPGLGAMAPPAPPLP 477
Score = 48.5 bits (114), Expect = 5e-05
Identities = 30/61 (49%), Positives = 30/61 (49%), Gaps = 6/61 (9%)
Query: 1515 MAREAPPLPPPPPP-----PLPPPPPPPLP-PPPPLPKTPRGGKRKHKPQAPAQPPQQSP 1568
MA APPLPPP P P PPPP P L PPPP P P G P P P SP
Sbjct: 469 MAPPAPPLPPPLPGSCEFLPPPPPPLPGLGCPPPPPPLLPGMGWGPPPPPPPLLPCTCSP 528
Query: 1569 P 1569
P
Sbjct: 529 P 529
>gi|149999380 inverted formin 2 isoform 1 [Homo sapiens]
Length = 1249
Score = 64.7 bits (156), Expect = 7e-10
Identities = 45/138 (32%), Positives = 57/138 (41%), Gaps = 22/138 (15%)
Query: 1454 RGRPRKQP---------TQFDEDSRDQMPVLEKCIDLPSKRGQKPSLSPLVLEPAASQDT 1504
+GRPR P D+ R P PS GQ+P+ + +Q
Sbjct: 345 KGRPRPSPLVKAHKSVQANLDQSQRGSSPQ-NTTTPKPSVEGQQPAAAAACEPVDHAQSE 403
Query: 1505 IMATIEAVIHMAREAPPLPPPPPPPLPP---PPPPPLPPPPPLPKTPRGGKRKHKPQAPA 1561
+ + + ++A PPPPPPPL P PPP PPPPPLP K P AP
Sbjct: 404 SILKVSQPRALEQQASTPPPPPPPPLLPGSSAEPPPPPPPPPLPSV----GAKALPTAPP 459
Query: 1562 QPP-----QQSPPQQPLP 1574
PP +PP PLP
Sbjct: 460 PPPLPGLGAMAPPAPPLP 477
Score = 48.5 bits (114), Expect = 5e-05
Identities = 30/61 (49%), Positives = 30/61 (49%), Gaps = 6/61 (9%)
Query: 1515 MAREAPPLPPPPPP-----PLPPPPPPPLP-PPPPLPKTPRGGKRKHKPQAPAQPPQQSP 1568
MA APPLPPP P P PPPP P L PPPP P P G P P P SP
Sbjct: 469 MAPPAPPLPPPLPGSCEFLPPPPPPLPGLGCPPPPPPLLPGMGWGPPPPPPPLLPCTCSP 528
Query: 1569 P 1569
P
Sbjct: 529 P 529
>gi|12597625 activating transcription factor 5 [Homo sapiens]
Length = 282
Score = 63.5 bits (153), Expect = 2e-09
Identities = 47/135 (34%), Positives = 58/135 (42%), Gaps = 29/135 (21%)
Query: 1481 LPSKRGQKPSLSPLVLEPAASQDTIMATIEAVIHMAREAPPLPPPPPPPLPPPPPPPLP- 1539
LP +PS +P LE AS + +E + +APPLPPP PPPLPPPP PP P
Sbjct: 83 LPPGTLPQPSPTPPDLEAMAS--LLKKELEQMEDFFLDAPPLPPPSPPPLPPPPLPPAPS 140
Query: 1540 ----------PPPPLPKT----------PRGGKRKHKP--QAPAQPPQQSPPQ----QPL 1573
P PP+ T G + P P QPP SPPQ P
Sbjct: 141 LPLSLPSFDLPQPPVLDTLDLLAIYCRNEAGQEEVGMPPLPPPQQPPPPSPPQPSRLAPY 200
Query: 1574 PQEEEVKAKRQRKSR 1588
P + R++K R
Sbjct: 201 PHPATTRGDRKQKKR 215
Score = 32.0 bits (71), Expect = 4.9
Identities = 21/57 (36%), Positives = 24/57 (42%), Gaps = 7/57 (12%)
Query: 1525 PPPPPLPPPP-PPPLPPPPPLPKTPRGGKRKHKP------QAPAQPPQQSPPQQPLP 1574
P PPLPP P P P PP L K++ + AP PP PP P P
Sbjct: 78 PLEPPLPPGTLPQPSPTPPDLEAMASLLKKELEQMEDFFLDAPPLPPPSPPPLPPPP 134
>gi|157817073 Cdc2-related kinase, arginine/serine-rich isoform 2
[Homo sapiens]
Length = 1481
Score = 63.5 bits (153), Expect = 2e-09
Identities = 111/489 (22%), Positives = 184/489 (37%), Gaps = 79/489 (16%)
Query: 1144 SGRLHKRKHKHKHKHKEDRILGTH---------DNLSGLFAGKATGFSSHILSERLSSAD 1194
S RLHK +H H+H+ D + + SG + +G S E
Sbjct: 105 SDRLHKHRH-HQHRRSRDLLKAKQTEKEKSQEVSSKSGSMKDRISGSSKRSNEETDDYGK 163
Query: 1195 KELPLVSEKNK-----HKEK-QKHQHSEAGHK----------ASKNNFEVDTLSTLSLSD 1238
++ S K HKEK +K + ++GHK K+ VD+ S S
Sbjct: 164 AQVAKSSSKESRSSKLHKEKTRKERELKSGHKDRSKSHRKRETPKSYKTVDSPKRRSRSP 223
Query: 1239 AQHWTQAKEKGDLSS-----EPVD-SCTKRYSGSGGD------GGSTRSENLDV------ 1280
+ W+ + ++ D S + D S ++ ++ S D G ++R +++
Sbjct: 224 HRKWSDSSKQDDSPSGASYGQDYDLSPSRSHTSSNYDSYKKSPGSTSRRQSVSPPYKEPS 283
Query: 1281 ---FSEMNPSN-DKWDSDVSGSKRR---SYEGFGTYREKDIQAFKMNRKERSSYDSSMSP 1333
S +PS + VS RR SYE G+Y + + R
Sbjct: 284 AYQSSTRSPSPYSRRQRSVSPYSRRRSSSYERSGSYSGRSPSPYGRRRSSSPFLSKRSLS 343
Query: 1334 GMPSPHLKVDQTAVHSKNEGSVPTMMTRKKPAAVDSVTIPPAPVLSLLAASAATSDAVGS 1393
P P K ++ S + ++KK ++ S +PV L +S +G+
Sbjct: 344 RSPLPSRKSMKSRSRSPAYSRHSSSHSKKKRSSSRSRHSSISPVRLPLNSS------LGA 397
Query: 1394 SLKKRFKRREIEAIQCEVR-KMCNYTKILSTKKNLDHVNKILKAKRLQRQSKTGNNFVKK 1452
L ++ K R A ++ K + + +K N ++AK +SK VK
Sbjct: 398 ELSRKKKERAAAAAAAKMDGKESKGSPVFLPRKE----NSSVEAKDSGLESKKLPRSVKL 453
Query: 1453 RRGRPRKQ---PTQFDEDSRDQMPVLEKCIDLPSKRGQKPSLSPLVL---EPAASQDTIM 1506
+ P + T + + ++ + +D S++ L +P A ++ I+
Sbjct: 454 EKSAPDTELVNVTHLNTEVKNSSDTGKVKLDENSEKHLVKDLKAQGTRDSKPIALKEEIV 513
Query: 1507 ATIEAVIHMAREAPPLP----PPPPPPLPPPPP--PPLPPPPPLPKTPRGGKRKHKPQAP 1560
E PPLP PPPP P PPP PPLPP PP+P P + P P
Sbjct: 514 TPKETETSEKETPPPLPTIASPPPPLPTTTPPPQTPPLPPLPPIPALP-----QQPPLPP 568
Query: 1561 AQPPQQSPP 1569
+QP P
Sbjct: 569 SQPAFSQVP 577
Score = 39.3 bits (90), Expect = 0.031
Identities = 39/164 (23%), Positives = 62/164 (37%), Gaps = 33/164 (20%)
Query: 1457 PRKQPTQFDEDSRDQMPVLEKCIDLPSKRGQKPSLSPLVLEPAASQDTIMATIEAVIHMA 1516
P++ P + + Q+P PS + ++S A SQ + +++ + +
Sbjct: 561 PQQPPLPPSQPAFSQVPASSTSTLPPSTHSKTSAVS----SQANSQPPVQVSVKTQVSVT 616
Query: 1517 REAPPLPPPPPPPLPPPPPPP-----------LPPPP----------------PLPKTPR 1549
P L PPLP PP P LP P PLP
Sbjct: 617 AAIPHLKTSTLPPLPLPPLLPGDDDMDSPKETLPSKPVKKEKEQRTRHLLTDLPLPPELP 676
Query: 1550 GGKRKHKPQAPAQPPQQSPPQQPLPQEEEVKAKRQRKSRGSESE 1593
GG P +P +P +PPQQP + ++ R + R +ES+
Sbjct: 677 GGDLS-PPDSP-EPKAITPPQQPYKKRPKICCPRYGERRQTESD 718
Score = 37.0 bits (84), Expect = 0.15
Identities = 35/133 (26%), Positives = 53/133 (39%), Gaps = 12/133 (9%)
Query: 690 LKAKAPPETSPGAAAIESKLGKQINVSKRGTIYIGKKRGRKPRAELPPPSEEPKTAIKHP 749
LKA+ ++ P A E K+ S++ T P PPP T
Sbjct: 495 LKAQGTRDSKPIALKEEIVTPKETETSEKET------PPPLPTIASPPPPLPTTTPPPQT 548
Query: 750 RPVSSQPDVPAVPSNFQSLVASSPAAMHPLSTQLGGSNGNLSPASTETNFSELKTMPNLQ 809
P+ P +PA+P L S PA +Q+ S+ + P ST + S + + N Q
Sbjct: 549 PPLPPLPPIPALPQQ-PPLPPSQPA-----FSQVPASSTSTLPPSTHSKTSAVSSQANSQ 602
Query: 810 PISALPTKTQKGI 822
P + KTQ +
Sbjct: 603 PPVQVSVKTQVSV 615
Score = 37.0 bits (84), Expect = 0.15
Identities = 23/71 (32%), Positives = 28/71 (39%), Gaps = 8/71 (11%)
Query: 1523 PPPPPPPLPPPPPPPL------PPPPPLPKTPRGGKRKHKPQAPAQPPQQSPPQQPL--P 1574
PP PP P PPPPPPPL P L + Q A+PP P + P
Sbjct: 1257 PPEPPGPPPPPPPPPLVEGDLSSAPQELNPAVTAALLQLLSQPEAEPPGHLPHEHQALRP 1316
Query: 1575 QEEEVKAKRQR 1585
E + + R
Sbjct: 1317 MEYSTRPRPNR 1327
Score = 35.8 bits (81), Expect = 0.34
Identities = 29/105 (27%), Positives = 40/105 (38%), Gaps = 17/105 (16%)
Query: 1497 EPAASQDTIMATIEAVIHMAREAPPLPP-------PPPPPLPPPPPPPLPPPPPLPKTPR 1549
EPA S + + + R P +P PP PP PPPPP PPPP +
Sbjct: 1222 EPAGSLEENNSDKNSGPQGPRRTPTMPQEEAAEKRPPEPPGPPPPP---PPPPLVEGDLS 1278
Query: 1550 GGKRKHKPQAPA------QPPQQSPPQQPLPQEEEVKAKRQRKSR 1588
++ P A P+ PP LP E + + +R
Sbjct: 1279 SAPQELNPAVTAALLQLLSQPEAEPPGH-LPHEHQALRPMEYSTR 1322
>gi|157817023 Cdc2-related kinase, arginine/serine-rich isoform 1
[Homo sapiens]
Length = 1490
Score = 63.5 bits (153), Expect = 2e-09
Identities = 111/489 (22%), Positives = 184/489 (37%), Gaps = 79/489 (16%)
Query: 1144 SGRLHKRKHKHKHKHKEDRILGTH---------DNLSGLFAGKATGFSSHILSERLSSAD 1194
S RLHK +H H+H+ D + + SG + +G S E
Sbjct: 105 SDRLHKHRH-HQHRRSRDLLKAKQTEKEKSQEVSSKSGSMKDRISGSSKRSNEETDDYGK 163
Query: 1195 KELPLVSEKNK-----HKEK-QKHQHSEAGHK----------ASKNNFEVDTLSTLSLSD 1238
++ S K HKEK +K + ++GHK K+ VD+ S S
Sbjct: 164 AQVAKSSSKESRSSKLHKEKTRKERELKSGHKDRSKSHRKRETPKSYKTVDSPKRRSRSP 223
Query: 1239 AQHWTQAKEKGDLSS-----EPVD-SCTKRYSGSGGD------GGSTRSENLDV------ 1280
+ W+ + ++ D S + D S ++ ++ S D G ++R +++
Sbjct: 224 HRKWSDSSKQDDSPSGASYGQDYDLSPSRSHTSSNYDSYKKSPGSTSRRQSVSPPYKEPS 283
Query: 1281 ---FSEMNPSN-DKWDSDVSGSKRR---SYEGFGTYREKDIQAFKMNRKERSSYDSSMSP 1333
S +PS + VS RR SYE G+Y + + R
Sbjct: 284 AYQSSTRSPSPYSRRQRSVSPYSRRRSSSYERSGSYSGRSPSPYGRRRSSSPFLSKRSLS 343
Query: 1334 GMPSPHLKVDQTAVHSKNEGSVPTMMTRKKPAAVDSVTIPPAPVLSLLAASAATSDAVGS 1393
P P K ++ S + ++KK ++ S +PV L +S +G+
Sbjct: 344 RSPLPSRKSMKSRSRSPAYSRHSSSHSKKKRSSSRSRHSSISPVRLPLNSS------LGA 397
Query: 1394 SLKKRFKRREIEAIQCEVR-KMCNYTKILSTKKNLDHVNKILKAKRLQRQSKTGNNFVKK 1452
L ++ K R A ++ K + + +K N ++AK +SK VK
Sbjct: 398 ELSRKKKERAAAAAAAKMDGKESKGSPVFLPRKE----NSSVEAKDSGLESKKLPRSVKL 453
Query: 1453 RRGRPRKQ---PTQFDEDSRDQMPVLEKCIDLPSKRGQKPSLSPLVL---EPAASQDTIM 1506
+ P + T + + ++ + +D S++ L +P A ++ I+
Sbjct: 454 EKSAPDTELVNVTHLNTEVKNSSDTGKVKLDENSEKHLVKDLKAQGTRDSKPIALKEEIV 513
Query: 1507 ATIEAVIHMAREAPPLP----PPPPPPLPPPPP--PPLPPPPPLPKTPRGGKRKHKPQAP 1560
E PPLP PPPP P PPP PPLPP PP+P P + P P
Sbjct: 514 TPKETETSEKETPPPLPTIASPPPPLPTTTPPPQTPPLPPLPPIPALP-----QQPPLPP 568
Query: 1561 AQPPQQSPP 1569
+QP P
Sbjct: 569 SQPAFSQVP 577
Score = 42.7 bits (99), Expect = 0.003
Identities = 27/81 (33%), Positives = 34/81 (41%), Gaps = 9/81 (11%)
Query: 1516 AREAPP--LPPPPPPPLPPPPPPPLPPPPPLPKTPRGGKRKHKPQAPA------QPPQQS 1567
A PP LPP PP PP PPPP PPPP + ++ P A P+
Sbjct: 1252 AAACPPHILPPEKRPPEPPGPPPPPPPPPLVEGDLSSAPQELNPAVTAALLQLLSQPEAE 1311
Query: 1568 PPQQPLPQEEEVKAKRQRKSR 1588
PP LP E + + +R
Sbjct: 1312 PPGH-LPHEHQALRPMEYSTR 1331
Score = 39.3 bits (90), Expect = 0.031
Identities = 39/164 (23%), Positives = 62/164 (37%), Gaps = 33/164 (20%)
Query: 1457 PRKQPTQFDEDSRDQMPVLEKCIDLPSKRGQKPSLSPLVLEPAASQDTIMATIEAVIHMA 1516
P++ P + + Q+P PS + ++S A SQ + +++ + +
Sbjct: 561 PQQPPLPPSQPAFSQVPASSTSTLPPSTHSKTSAVS----SQANSQPPVQVSVKTQVSVT 616
Query: 1517 REAPPLPPPPPPPLPPPPPPP-----------LPPPP----------------PLPKTPR 1549
P L PPLP PP P LP P PLP
Sbjct: 617 AAIPHLKTSTLPPLPLPPLLPGDDDMDSPKETLPSKPVKKEKEQRTRHLLTDLPLPPELP 676
Query: 1550 GGKRKHKPQAPAQPPQQSPPQQPLPQEEEVKAKRQRKSRGSESE 1593
GG P +P +P +PPQQP + ++ R + R +ES+
Sbjct: 677 GGDLS-PPDSP-EPKAITPPQQPYKKRPKICCPRYGERRQTESD 718
Score = 37.0 bits (84), Expect = 0.15
Identities = 35/133 (26%), Positives = 53/133 (39%), Gaps = 12/133 (9%)
Query: 690 LKAKAPPETSPGAAAIESKLGKQINVSKRGTIYIGKKRGRKPRAELPPPSEEPKTAIKHP 749
LKA+ ++ P A E K+ S++ T P PPP T
Sbjct: 495 LKAQGTRDSKPIALKEEIVTPKETETSEKET------PPPLPTIASPPPPLPTTTPPPQT 548
Query: 750 RPVSSQPDVPAVPSNFQSLVASSPAAMHPLSTQLGGSNGNLSPASTETNFSELKTMPNLQ 809
P+ P +PA+P L S PA +Q+ S+ + P ST + S + + N Q
Sbjct: 549 PPLPPLPPIPALPQQ-PPLPPSQPA-----FSQVPASSTSTLPPSTHSKTSAVSSQANSQ 602
Query: 810 PISALPTKTQKGI 822
P + KTQ +
Sbjct: 603 PPVQVSVKTQVSV 615
Score = 31.2 bits (69), Expect = 8.4
Identities = 25/96 (26%), Positives = 34/96 (35%), Gaps = 12/96 (12%)
Query: 1498 PAASQDTIMATIEAVIHMAREAPPLPPPPPPPLPPPPPPPL------PPPPPLPKTPRGG 1551
P Q+ A ++ + P P PPPP PPPPPL P L
Sbjct: 1245 PTMPQEEAAACPPHILPPEKRPPEPPGPPPP----PPPPPLVEGDLSSAPQELNPAVTAA 1300
Query: 1552 KRKHKPQAPAQPPQQSPPQQPL--PQEEEVKAKRQR 1585
+ Q A+PP P + P E + + R
Sbjct: 1301 LLQLLSQPEAEPPGHLPHEHQALRPMEYSTRPRPNR 1336
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 62.4 bits (150), Expect = 3e-09
Identities = 176/856 (20%), Positives = 274/856 (32%), Gaps = 112/856 (13%)
Query: 21 PVSSAKPPAAPGCAGEPLLSTPGPGKGIPVGGERMEPEEEDELGSGRDVDSN--SNADSE 78
P SS K P G A + + ST P + + E +E+ V N S++ S
Sbjct: 72 PPSSKKAPPPSG-ASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSSS 130
Query: 79 KWVAGDGLEEQEFSIKEANFTEGSLKLKIQTTK--RAKKPPKNLENYICPPEIKITIK-- 134
+ + + + S A E KLK++ K R KK P PP +
Sbjct: 131 SSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPK-----PPVVDEAGSGL 185
Query: 135 QSGDQKVSRAGKNSKATKEEERSHSKKKLLTASDLAASDLKGFQPQAYERPQKHSTLHYD 194
+GD KV+ +T + + + K+ TA + + P + + T++ +
Sbjct: 186 DNGDFKVTTP---DTSTTQHNKVSTSPKITTAKPI--NPRPSLPPNSDTSKETSLTVNKE 240
Query: 195 TGLPQDFTGDTLKPKHQQKSSSQNHMDWSTNSDSGPVTQNCFISPESGRETASTSKIPAL 254
T T++ K ++ Q D + S TQ+ I S ++ A TSK+ A
Sbjct: 241 T---------TVETKETTTTNKQTSTDGKEKTTSAKETQS--IEKTSAKDLAPTSKVLAK 289
Query: 255 EPVASFAKAQG------KKGSAGNTWSQLSNNNKDLLLGGVAPSPSS-HSSPAPPSSSAE 307
+ +G K+ + S K+ P+P++ S+P P A
Sbjct: 290 PTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKE-------PTPTTIKSAPTTPKEPA- 341
Query: 308 CNGLQPLVDQDGGGTKEPPEPPTVGSKKKSSKKDVISQTIPNPDLDWVKNAQ---KAFDN 364
P + T + P P T ++ K+ T P K+A K
Sbjct: 342 -----PTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAP 396
Query: 365 TEGKREGYSADSAQEASPARQNVSSASNPENDSSHVRITIPIKAPSLDPTNHKRKKRQSI 424
T K+ + + +E +P + + P+ + + P PT K+ +
Sbjct: 397 TTPKKP--APTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTP 454
Query: 425 KAVVEKIMPEKALASGITMSSEVVNRILSNSEGNKKDPRVPKLSKMIENESPSVGLETGG 484
K E A + E + P+ P + +P+ E
Sbjct: 455 KEPAPTTPKEPAPTT--------------TKEPSPTTPKEP--APTTTKSAPTTTKEPAP 498
Query: 485 NAEKVIPGGVSKPRKPPMVMTPPTCTDHSPSRKLPEIQHPKFAAKRRWTCSKPKPSTMLR 544
K P +P P P T P+ P+ P T +P P+T
Sbjct: 499 TTTKSAPTTPKEP-SPTTTKEPAPTTPKEPAPTTPKKPAPT-------TPKEPAPTTPKE 550
Query: 545 EAVMATSDKLMLEPPSAYPITPSSPLYTNTDSLTVITPVKKKRGRPKKQPLLTVE----- 599
A T P P TP T LT TP K P+K T E
Sbjct: 551 PAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPT 610
Query: 600 TIHEGTSTSPVSPISREFPGTKKRKRRRNLAKLAQLVPGEDKPMSEMKFHKKVGK--LGV 657
T E T T+P P P T K + A P E P + + K
Sbjct: 611 TPEEPTPTTPEEPA----PTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPT 666
Query: 658 LDKKTIKTINK--MKTLKRKNILNQILSCSSSVALKA---KAPPETSPGAAAIESK---- 708
K T T K T +K ++ ++ K P T G A K
Sbjct: 667 TPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAP 726
Query: 709 --LGKQINVSKRGTIYIGKKRGRKPRAELPPPSEEPKTAIKHPRPVSSQPDVPAVPSNFQ 766
+ + +GT K + P P E T K P +S P P
Sbjct: 727 TTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETA 786
Query: 767 SLVASSPAAMHPLSTQLGGSNGNLSPASTETNFSELKTMPNLQPISALPTKTQKGIHSGT 826
PA P +P + SE+ T + PT K T
Sbjct: 787 PTTPKEPAPTTPKKP------APTTPETPPPTTSEVSTPTTTKE----PTTIHKSPDEST 836
Query: 827 WKLS---PPRLMANSP 839
+LS P+ + NSP
Sbjct: 837 PELSAEPTPKALENSP 852
Score = 46.2 bits (108), Expect = 3e-04
Identities = 25/95 (26%), Positives = 39/95 (41%), Gaps = 2/95 (2%)
Query: 1482 PSKRGQKPSLSPLVLEPAASQDTIMATIEAVIHMAREAPPLPPPPPPPLPPPPPPPLPPP 1541
P+ + +P P +++ T ++ +E P P P P P P P P
Sbjct: 357 PTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPK 416
Query: 1542 PPLPKTPRGGKRKHKPQAPAQPPQQSP--PQQPLP 1574
P P TP+ K AP P + +P P++P P
Sbjct: 417 EPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAP 451
Score = 40.0 bits (92), Expect = 0.018
Identities = 91/466 (19%), Positives = 147/466 (31%), Gaps = 87/466 (18%)
Query: 1134 PPKVGSASLSSGRLHKRKHKHKHKHK----------EDRILGTHDNLSGLFAGKATGFSS 1183
PP S ++ S K +K K K E + ++ S + ++
Sbjct: 80 PPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSSSSSSSSSTIR 139
Query: 1184 HILSERLSSADKELPL---VSEKNKHKEKQKHQHS-----EAGHKASKNNFEVDTLSTLS 1235
I S + S+A++EL V + K++ K+K EAG +F+V T T +
Sbjct: 140 KIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTST 199
Query: 1236 -----LSDAQHWTQAKEKGDLSSEPVDSCTKRYSGSGGDGGSTRSENLDVFSEMNPSNDK 1290
+S + T AK S P +S T + + + +T + S D
Sbjct: 200 TQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDG 259
Query: 1291 WDSDVSGSKRRSYEGFGTYREKDIQAFKMNRKERSSYDSSMSPGMPSPHLKVDQTAVHSK 1350
+ S + +S E K + K+ + ++ P A+ +
Sbjct: 260 KEKTTSAKETQSIE-------------KTSAKDLAPTSKVLAKPTPKAETTTKGPALTTP 306
Query: 1351 NEGSVPTMMTRKKPAAVDSVTIPPAPVLSLLAASAATSDAVGSSLKKRFKRREIEAIQCE 1410
E PT T K+PA+ T P P + + ++ T + K E
Sbjct: 307 KE---PTPTTPKEPAS----TTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTT 359
Query: 1411 VRKMCNYTKILSTKKNLDHVNKILKAKRLQRQSKTGNNFVKKRRGRPRKQPTQFDEDSRD 1470
++ T K+ K+P S
Sbjct: 360 TKEPAPTTP-------------------------------KEPAPTTTKEPAPTTTKSAP 388
Query: 1471 QMPVLEKCIDLPSKRGQKPSLSPLVLEPAASQDTIMATIEAVIHMAREAPPLPPPPPPPL 1530
P E P K P P ++ T + +E P P P P
Sbjct: 389 TTPK-EPAPTTPKKPAPTTPKEPA---PTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPT 444
Query: 1531 PPPPPPPLPPPPPLPKTPRGGKRKHKPQAPAQPPQQSP--PQQPLP 1574
P P P P P P TP K AP + SP P++P P
Sbjct: 445 APKKPAPTTPKEPAPTTP-------KEPAPTTTKEPSPTTPKEPAP 483
Score = 37.4 bits (85), Expect = 0.12
Identities = 26/97 (26%), Positives = 36/97 (37%), Gaps = 4/97 (4%)
Query: 1482 PSKRGQKPSLSPLVLEPAASQDTIMATIEAVIHMAREAP-PLPPPPPPPLPPPPPPPLPP 1540
P+ + +P P + T E + E P P P P P P P P
Sbjct: 561 PTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTP 620
Query: 1541 PPPLPKTPRGGK-RKHKPQAPAQPPQQSP--PQQPLP 1574
P P TP+ K AP P + +P P++P P
Sbjct: 621 EEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAP 657
Score = 37.0 bits (84), Expect = 0.15
Identities = 24/103 (23%), Positives = 34/103 (33%), Gaps = 10/103 (9%)
Query: 1482 PSKRGQKPSLSPLVLEPAASQDTIMATIEAVIHMAREAPPLPPPPPP----------PLP 1531
P+ + +P P ++ T E + AP P P P P
Sbjct: 467 PTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKE 526
Query: 1532 PPPPPPLPPPPPLPKTPRGGKRKHKPQAPAQPPQQSPPQQPLP 1574
P P P P P PK P K + P + P++P P
Sbjct: 527 PAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAP 569
Score = 37.0 bits (84), Expect = 0.15
Identities = 26/100 (26%), Positives = 39/100 (39%), Gaps = 15/100 (15%)
Query: 1487 QKPS-LSPLVLEPAASQDTIMATIE---------AVIHMAREAPPLPPPPPPPLPPPPPP 1536
+KP+ +P L P ++ T E A + +E P P P P P P
Sbjct: 597 EKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPA 656
Query: 1537 PLPPPPPLPKTPRGGKRKHKPQAPAQPPQQSPPQQPLPQE 1576
P P P TP+G + P + P++P P+E
Sbjct: 657 PTTPKETAPTTPKG-----TAPTTLKEPAPTTPKKPAPKE 691
Score = 35.4 bits (80), Expect = 0.44
Identities = 19/60 (31%), Positives = 25/60 (41%), Gaps = 8/60 (13%)
Query: 1517 REAPPLPPPPPPPLPPPPPPPLPPPPPLPKTPRGGKRKHKPQAPAQP----PQQSPPQQP 1572
+E P P P P P P P P P P T +K P P +P P+++ P P
Sbjct: 525 KEPAPTTPKKPAPTTPKEPAPTTPKEPAPTT----TKKPAPTTPKEPAPTTPKETAPTTP 580
Score = 35.4 bits (80), Expect = 0.44
Identities = 21/80 (26%), Positives = 30/80 (37%), Gaps = 5/80 (6%)
Query: 1497 EPAASQDTIMATIEAVIHMAREAPPLPPPPPPPLPPPPPPPLPPPPPLPKTPRGGKRKHK 1556
+PA + T E + P P P P P P P P P TP+G
Sbjct: 686 KPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKG-----T 740
Query: 1557 PQAPAQPPQQSPPQQPLPQE 1576
+ P + P++P P+E
Sbjct: 741 APTTLKEPAPTTPKKPAPKE 760
Score = 34.7 bits (78), Expect = 0.76
Identities = 19/81 (23%), Positives = 29/81 (35%), Gaps = 13/81 (16%)
Query: 1498 PAASQDTIMATIEAVIHMAREAPPLPPPPPPPLPPPPPPPLPPPPPLPKTPRGGKRKHKP 1557
P ++ T + ++ P P P P P P P P P P TP+
Sbjct: 365 PTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPK-------- 416
Query: 1558 QAPAQPPQQSPPQQPLPQEEE 1578
P + P++P P +E
Sbjct: 417 -----EPTPTTPKEPAPTTKE 432
Score = 33.5 bits (75), Expect = 1.7
Identities = 19/62 (30%), Positives = 24/62 (38%), Gaps = 2/62 (3%)
Query: 1519 APPLPPPPPPPLPPPPPPPLPPPPPLPKTPRGGKRKHKPQAPAQPPQQSP--PQQPLPQE 1576
AP P P P P P P P P T + K AP P + +P P++ P
Sbjct: 528 APTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTT 587
Query: 1577 EE 1578
E
Sbjct: 588 PE 589
Score = 33.1 bits (74), Expect = 2.2
Identities = 24/85 (28%), Positives = 29/85 (34%), Gaps = 13/85 (15%)
Query: 1516 AREAPPLPPPPPPPLPPPPPPPLPPP------PPLPKTPRGGKRKHKPQAPAQP------ 1563
A P P P P P P P P P PK P K P P +P
Sbjct: 302 ALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTK 361
Query: 1564 -PQQSPPQQPLPQEEEVKAKRQRKS 1587
P + P++P P + A KS
Sbjct: 362 EPAPTTPKEPAPTTTKEPAPTTTKS 386
Score = 32.3 bits (72), Expect = 3.8
Identities = 21/66 (31%), Positives = 26/66 (39%), Gaps = 8/66 (12%)
Query: 1521 PLPPPPPPPLPPPP-----PPPLPPPPPLPKTPR-GGKRKHKPQAPAQPPQQSP--PQQP 1572
P P P P P P P P P P P TP+ K P P + +P P++P
Sbjct: 540 PKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKP 599
Query: 1573 LPQEEE 1578
P E
Sbjct: 600 APTTPE 605
Score = 32.0 bits (71), Expect = 4.9
Identities = 20/71 (28%), Positives = 27/71 (38%), Gaps = 5/71 (7%)
Query: 1517 REAPPLPPPPPPPLPPPPPPPLPP--PPPLPKTPRGGKRKHKPQAPAQPPQQSPPQ---Q 1571
+E P P P P P P P P PPP +P + P +S P+ +
Sbjct: 783 KETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAE 842
Query: 1572 PLPQEEEVKAK 1582
P P+ E K
Sbjct: 843 PTPKALENSPK 853
Score = 31.6 bits (70), Expect = 6.4
Identities = 20/72 (27%), Positives = 27/72 (37%), Gaps = 9/72 (12%)
Query: 1517 REAPPLPPPPPPPLPPPPPPPLPPPPPLPKTPRGGKRKHKPQAPAQPPQQSP--PQQPLP 1574
+E P P P P P P P P TP + AP P + +P P++P P
Sbjct: 573 KETAPTTPKKLTPTTPEKLAPTTPEKPAPTTP-------EELAPTTPEEPTPTTPEEPAP 625
Query: 1575 QEEEVKAKRQRK 1586
+ A K
Sbjct: 626 TTPKAAAPNTPK 637
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 62.4 bits (150), Expect = 3e-09
Identities = 176/856 (20%), Positives = 274/856 (32%), Gaps = 112/856 (13%)
Query: 21 PVSSAKPPAAPGCAGEPLLSTPGPGKGIPVGGERMEPEEEDELGSGRDVDSN--SNADSE 78
P SS K P G A + + ST P + + E +E+ V N S++ S
Sbjct: 113 PPSSKKAPPPSG-ASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSSS 171
Query: 79 KWVAGDGLEEQEFSIKEANFTEGSLKLKIQTTK--RAKKPPKNLENYICPPEIKITIK-- 134
+ + + + S A E KLK++ K R KK P PP +
Sbjct: 172 SSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPK-----PPVVDEAGSGL 226
Query: 135 QSGDQKVSRAGKNSKATKEEERSHSKKKLLTASDLAASDLKGFQPQAYERPQKHSTLHYD 194
+GD KV+ +T + + + K+ TA + + P + + T++ +
Sbjct: 227 DNGDFKVTTP---DTSTTQHNKVSTSPKITTAKPI--NPRPSLPPNSDTSKETSLTVNKE 281
Query: 195 TGLPQDFTGDTLKPKHQQKSSSQNHMDWSTNSDSGPVTQNCFISPESGRETASTSKIPAL 254
T T++ K ++ Q D + S TQ+ I S ++ A TSK+ A
Sbjct: 282 T---------TVETKETTTTNKQTSTDGKEKTTSAKETQS--IEKTSAKDLAPTSKVLAK 330
Query: 255 EPVASFAKAQG------KKGSAGNTWSQLSNNNKDLLLGGVAPSPSS-HSSPAPPSSSAE 307
+ +G K+ + S K+ P+P++ S+P P A
Sbjct: 331 PTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKE-------PTPTTIKSAPTTPKEPA- 382
Query: 308 CNGLQPLVDQDGGGTKEPPEPPTVGSKKKSSKKDVISQTIPNPDLDWVKNAQ---KAFDN 364
P + T + P P T ++ K+ T P K+A K
Sbjct: 383 -----PTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAP 437
Query: 365 TEGKREGYSADSAQEASPARQNVSSASNPENDSSHVRITIPIKAPSLDPTNHKRKKRQSI 424
T K+ + + +E +P + + P+ + + P PT K+ +
Sbjct: 438 TTPKKP--APTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTP 495
Query: 425 KAVVEKIMPEKALASGITMSSEVVNRILSNSEGNKKDPRVPKLSKMIENESPSVGLETGG 484
K E A + E + P+ P + +P+ E
Sbjct: 496 KEPAPTTPKEPAPTT--------------TKEPSPTTPKEP--APTTTKSAPTTTKEPAP 539
Query: 485 NAEKVIPGGVSKPRKPPMVMTPPTCTDHSPSRKLPEIQHPKFAAKRRWTCSKPKPSTMLR 544
K P +P P P T P+ P+ P T +P P+T
Sbjct: 540 TTTKSAPTTPKEP-SPTTTKEPAPTTPKEPAPTTPKKPAPT-------TPKEPAPTTPKE 591
Query: 545 EAVMATSDKLMLEPPSAYPITPSSPLYTNTDSLTVITPVKKKRGRPKKQPLLTVE----- 599
A T P P TP T LT TP K P+K T E
Sbjct: 592 PAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPT 651
Query: 600 TIHEGTSTSPVSPISREFPGTKKRKRRRNLAKLAQLVPGEDKPMSEMKFHKKVGK--LGV 657
T E T T+P P P T K + A P E P + + K
Sbjct: 652 TPEEPTPTTPEEPA----PTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPT 707
Query: 658 LDKKTIKTINK--MKTLKRKNILNQILSCSSSVALKA---KAPPETSPGAAAIESK---- 708
K T T K T +K ++ ++ K P T G A K
Sbjct: 708 TPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAP 767
Query: 709 --LGKQINVSKRGTIYIGKKRGRKPRAELPPPSEEPKTAIKHPRPVSSQPDVPAVPSNFQ 766
+ + +GT K + P P E T K P +S P P
Sbjct: 768 TTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETA 827
Query: 767 SLVASSPAAMHPLSTQLGGSNGNLSPASTETNFSELKTMPNLQPISALPTKTQKGIHSGT 826
PA P +P + SE+ T + PT K T
Sbjct: 828 PTTPKEPAPTTPKKP------APTTPETPPPTTSEVSTPTTTKE----PTTIHKSPDEST 877
Query: 827 WKLS---PPRLMANSP 839
+LS P+ + NSP
Sbjct: 878 PELSAEPTPKALENSP 893
Score = 46.2 bits (108), Expect = 3e-04
Identities = 25/95 (26%), Positives = 39/95 (41%), Gaps = 2/95 (2%)
Query: 1482 PSKRGQKPSLSPLVLEPAASQDTIMATIEAVIHMAREAPPLPPPPPPPLPPPPPPPLPPP 1541
P+ + +P P +++ T ++ +E P P P P P P P P
Sbjct: 398 PTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPK 457
Query: 1542 PPLPKTPRGGKRKHKPQAPAQPPQQSP--PQQPLP 1574
P P TP+ K AP P + +P P++P P
Sbjct: 458 EPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAP 492
Score = 40.0 bits (92), Expect = 0.018
Identities = 91/466 (19%), Positives = 147/466 (31%), Gaps = 87/466 (18%)
Query: 1134 PPKVGSASLSSGRLHKRKHKHKHKHK----------EDRILGTHDNLSGLFAGKATGFSS 1183
PP S ++ S K +K K K E + ++ S + ++
Sbjct: 121 PPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSSSSSSSSSTIR 180
Query: 1184 HILSERLSSADKELPL---VSEKNKHKEKQKHQHS-----EAGHKASKNNFEVDTLSTLS 1235
I S + S+A++EL V + K++ K+K EAG +F+V T T +
Sbjct: 181 KIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTST 240
Query: 1236 -----LSDAQHWTQAKEKGDLSSEPVDSCTKRYSGSGGDGGSTRSENLDVFSEMNPSNDK 1290
+S + T AK S P +S T + + + +T + S D
Sbjct: 241 TQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDG 300
Query: 1291 WDSDVSGSKRRSYEGFGTYREKDIQAFKMNRKERSSYDSSMSPGMPSPHLKVDQTAVHSK 1350
+ S + +S E K + K+ + ++ P A+ +
Sbjct: 301 KEKTTSAKETQSIE-------------KTSAKDLAPTSKVLAKPTPKAETTTKGPALTTP 347
Query: 1351 NEGSVPTMMTRKKPAAVDSVTIPPAPVLSLLAASAATSDAVGSSLKKRFKRREIEAIQCE 1410
E PT T K+PA+ T P P + + ++ T + K E
Sbjct: 348 KE---PTPTTPKEPAS----TTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTT 400
Query: 1411 VRKMCNYTKILSTKKNLDHVNKILKAKRLQRQSKTGNNFVKKRRGRPRKQPTQFDEDSRD 1470
++ T K+ K+P S
Sbjct: 401 TKEPAPTTP-------------------------------KEPAPTTTKEPAPTTTKSAP 429
Query: 1471 QMPVLEKCIDLPSKRGQKPSLSPLVLEPAASQDTIMATIEAVIHMAREAPPLPPPPPPPL 1530
P E P K P P ++ T + +E P P P P
Sbjct: 430 TTPK-EPAPTTPKKPAPTTPKEPA---PTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPT 485
Query: 1531 PPPPPPPLPPPPPLPKTPRGGKRKHKPQAPAQPPQQSP--PQQPLP 1574
P P P P P P TP K AP + SP P++P P
Sbjct: 486 APKKPAPTTPKEPAPTTP-------KEPAPTTTKEPSPTTPKEPAP 524
Score = 37.4 bits (85), Expect = 0.12
Identities = 26/97 (26%), Positives = 36/97 (37%), Gaps = 4/97 (4%)
Query: 1482 PSKRGQKPSLSPLVLEPAASQDTIMATIEAVIHMAREAP-PLPPPPPPPLPPPPPPPLPP 1540
P+ + +P P + T E + E P P P P P P P P
Sbjct: 602 PTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTP 661
Query: 1541 PPPLPKTPRGGK-RKHKPQAPAQPPQQSP--PQQPLP 1574
P P TP+ K AP P + +P P++P P
Sbjct: 662 EEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAP 698
Score = 37.0 bits (84), Expect = 0.15
Identities = 24/103 (23%), Positives = 34/103 (33%), Gaps = 10/103 (9%)
Query: 1482 PSKRGQKPSLSPLVLEPAASQDTIMATIEAVIHMAREAPPLPPPPPP----------PLP 1531
P+ + +P P ++ T E + AP P P P P
Sbjct: 508 PTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKE 567
Query: 1532 PPPPPPLPPPPPLPKTPRGGKRKHKPQAPAQPPQQSPPQQPLP 1574
P P P P P PK P K + P + P++P P
Sbjct: 568 PAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAP 610
Score = 37.0 bits (84), Expect = 0.15
Identities = 26/100 (26%), Positives = 39/100 (39%), Gaps = 15/100 (15%)
Query: 1487 QKPS-LSPLVLEPAASQDTIMATIE---------AVIHMAREAPPLPPPPPPPLPPPPPP 1536
+KP+ +P L P ++ T E A + +E P P P P P P
Sbjct: 638 EKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPA 697
Query: 1537 PLPPPPPLPKTPRGGKRKHKPQAPAQPPQQSPPQQPLPQE 1576
P P P TP+G + P + P++P P+E
Sbjct: 698 PTTPKETAPTTPKG-----TAPTTLKEPAPTTPKKPAPKE 732
Score = 35.4 bits (80), Expect = 0.44
Identities = 19/60 (31%), Positives = 25/60 (41%), Gaps = 8/60 (13%)
Query: 1517 REAPPLPPPPPPPLPPPPPPPLPPPPPLPKTPRGGKRKHKPQAPAQP----PQQSPPQQP 1572
+E P P P P P P P P P P T +K P P +P P+++ P P
Sbjct: 566 KEPAPTTPKKPAPTTPKEPAPTTPKEPAPTT----TKKPAPTTPKEPAPTTPKETAPTTP 621
Score = 35.4 bits (80), Expect = 0.44
Identities = 21/80 (26%), Positives = 30/80 (37%), Gaps = 5/80 (6%)
Query: 1497 EPAASQDTIMATIEAVIHMAREAPPLPPPPPPPLPPPPPPPLPPPPPLPKTPRGGKRKHK 1556
+PA + T E + P P P P P P P P P TP+G
Sbjct: 727 KPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKG-----T 781
Query: 1557 PQAPAQPPQQSPPQQPLPQE 1576
+ P + P++P P+E
Sbjct: 782 APTTLKEPAPTTPKKPAPKE 801
Score = 34.7 bits (78), Expect = 0.76
Identities = 19/81 (23%), Positives = 29/81 (35%), Gaps = 13/81 (16%)
Query: 1498 PAASQDTIMATIEAVIHMAREAPPLPPPPPPPLPPPPPPPLPPPPPLPKTPRGGKRKHKP 1557
P ++ T + ++ P P P P P P P P P P TP+
Sbjct: 406 PTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPK-------- 457
Query: 1558 QAPAQPPQQSPPQQPLPQEEE 1578
P + P++P P +E
Sbjct: 458 -----EPTPTTPKEPAPTTKE 473
Score = 33.5 bits (75), Expect = 1.7
Identities = 19/62 (30%), Positives = 24/62 (38%), Gaps = 2/62 (3%)
Query: 1519 APPLPPPPPPPLPPPPPPPLPPPPPLPKTPRGGKRKHKPQAPAQPPQQSP--PQQPLPQE 1576
AP P P P P P P P P T + K AP P + +P P++ P
Sbjct: 569 APTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTT 628
Query: 1577 EE 1578
E
Sbjct: 629 PE 630
Score = 33.1 bits (74), Expect = 2.2
Identities = 24/85 (28%), Positives = 29/85 (34%), Gaps = 13/85 (15%)
Query: 1516 AREAPPLPPPPPPPLPPPPPPPLPPP------PPLPKTPRGGKRKHKPQAPAQP------ 1563
A P P P P P P P P P PK P K P P +P
Sbjct: 343 ALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTK 402
Query: 1564 -PQQSPPQQPLPQEEEVKAKRQRKS 1587
P + P++P P + A KS
Sbjct: 403 EPAPTTPKEPAPTTTKEPAPTTTKS 427
Score = 32.3 bits (72), Expect = 3.8
Identities = 21/66 (31%), Positives = 26/66 (39%), Gaps = 8/66 (12%)
Query: 1521 PLPPPPPPPLPPPP-----PPPLPPPPPLPKTPR-GGKRKHKPQAPAQPPQQSP--PQQP 1572
P P P P P P P P P P P TP+ K P P + +P P++P
Sbjct: 581 PKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKP 640
Query: 1573 LPQEEE 1578
P E
Sbjct: 641 APTTPE 646
Score = 32.0 bits (71), Expect = 4.9
Identities = 20/71 (28%), Positives = 27/71 (38%), Gaps = 5/71 (7%)
Query: 1517 REAPPLPPPPPPPLPPPPPPPLPP--PPPLPKTPRGGKRKHKPQAPAQPPQQSPPQ---Q 1571
+E P P P P P P P P PPP +P + P +S P+ +
Sbjct: 824 KETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAE 883
Query: 1572 PLPQEEEVKAK 1582
P P+ E K
Sbjct: 884 PTPKALENSPK 894
Score = 31.6 bits (70), Expect = 6.4
Identities = 20/72 (27%), Positives = 27/72 (37%), Gaps = 9/72 (12%)
Query: 1517 REAPPLPPPPPPPLPPPPPPPLPPPPPLPKTPRGGKRKHKPQAPAQPPQQSP--PQQPLP 1574
+E P P P P P P P P TP + AP P + +P P++P P
Sbjct: 614 KETAPTTPKKLTPTTPEKLAPTTPEKPAPTTP-------EELAPTTPEEPTPTTPEEPAP 666
Query: 1575 QEEEVKAKRQRK 1586
+ A K
Sbjct: 667 TTPKAAAPNTPK 678
>gi|122937496 WAS/WASL interacting protein family, member 3 [Homo
sapiens]
Length = 483
Score = 62.4 bits (150), Expect = 3e-09
Identities = 39/107 (36%), Positives = 47/107 (43%), Gaps = 17/107 (15%)
Query: 1482 PSKRGQKPSLSPLVLEPAASQDTIMATIEAVIHMAREAPPLPPPPPPPLPPPPPPPLPPP 1541
PS R ++S ++ PA+ + + AR APP P P PP P PPPPP P P
Sbjct: 131 PSPRLPNKTISGPLIPPASPR---LGNTSEAHGAARTAPPRPNVPAPPPPTPPPPPPPLP 187
Query: 1542 PPLP-----KTP---------RGGKRKHKPQAPAQPPQQSPPQQPLP 1574
PPLP KTP +G P P PP PP P P
Sbjct: 188 PPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPPPPTP 234
Score = 58.2 bits (139), Expect = 6e-08
Identities = 42/117 (35%), Positives = 48/117 (41%), Gaps = 31/117 (26%)
Query: 1482 PSKRGQKPSLSPLVLEPAASQDTIMATIEAVIHMAREAPPLPPPPPPPLPPPPPPPLPP- 1540
P P +PLV P + + A P PPPPPPP PPP PPPLPP
Sbjct: 188 PPLPSSSPIKTPLVSPPGPLTKGNLPVV------APPVPCAPPPPPPP-PPPTPPPLPPA 240
Query: 1541 --------------------PPPLPKTPRGG--KRKHKPQAPAQPPQQSP-PQQPLP 1574
PPPLP P G K +P +PAQ Q+ P P PLP
Sbjct: 241 SVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPAQDAQEPPAPPPPLP 297
Score = 56.2 bits (134), Expect = 2e-07
Identities = 21/28 (75%), Positives = 22/28 (78%)
Query: 1521 PLPPPPPPPLPPPPPPPLPPPPPLPKTP 1548
P+PPPPPPPLPPPPPP PPPP P P
Sbjct: 2 PVPPPPPPPLPPPPPPLGAPPPPPPSAP 29
Score = 51.2 bits (121), Expect = 8e-06
Identities = 31/90 (34%), Positives = 31/90 (34%), Gaps = 35/90 (38%)
Query: 1520 PPLPPPPPPPLPPP----------------------------------PPPPLPPPPPLP 1545
PP PPPPPPPLPPP PPPP PPPP P
Sbjct: 176 PPTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPPPPTPP 235
Query: 1546 KTPRGGKRKHKPQAPAQPPQQSPP-QQPLP 1574
P K P P PP PLP
Sbjct: 236 PLPPASVLSDKAVKPQLAPLHLPPIPPPLP 265
Score = 46.2 bits (108), Expect = 3e-04
Identities = 28/77 (36%), Positives = 36/77 (46%), Gaps = 6/77 (7%)
Query: 1520 PPLPPPPPPPLPPPPPPPLPPPPPLPKTPRGGKRKHKPQ---APAQPPQQSPPQQPLPQE 1576
PPLPPPPPP PPPPPP PP T R+ P+ A QQ + + Q
Sbjct: 9 PPLPPPPPPLGAPPPPPPSAPP---VSTDTSSLRRADPKGRSALLADIQQGTRLRKVTQI 65
Query: 1577 EEVKAKRQRKSRGSESE 1593
+ A + S+G+ E
Sbjct: 66 NDRSAPQIESSKGTNKE 82
Score = 44.3 bits (103), Expect = 0.001
Identities = 36/104 (34%), Positives = 44/104 (42%), Gaps = 16/104 (15%)
Query: 1489 PSLSPLVLEPAASQDTIMATIEAVIHMAREAPPLPPPPPPP---------LPPPPPPPL- 1538
P PL L P + A + A+E PP PPPP PP LP PP P +
Sbjct: 259 PIPPPLPLLPPCGYPGLKAEPASPAQDAQE-PPAPPPPLPPYASCSPRASLPAPPLPGVN 317
Query: 1539 ----PPPPPLPKTPRGGKRKHKPQAPAQPPQQSPP-QQPLPQEE 1577
PPP PK+P K A A P +PP QP Q++
Sbjct: 318 SSSETPPPLPPKSPSFQAPPQKAGAQALPAPPAPPGSQPFLQKK 361
Score = 35.0 bits (79), Expect = 0.58
Identities = 17/37 (45%), Positives = 18/37 (48%), Gaps = 8/37 (21%)
Query: 1533 PPPPPLPPPPPLPKTPRGGKRKHKPQAPAQPPQQSPP 1569
P PPP PPP P P P G AP PP +PP
Sbjct: 2 PVPPPPPPPLPPPPPPLG--------APPPPPPSAPP 30
>gi|56549696 E1A binding protein p400 [Homo sapiens]
Length = 3122
Score = 61.6 bits (148), Expect = 6e-09
Identities = 30/79 (37%), Positives = 38/79 (48%), Gaps = 5/79 (6%)
Query: 1510 EAVIHMAREAPPLPPPPPPPLPPPPPPPLPPPPPLPKTPRGGKRKHKPQAPAQPPQQSPP 1569
+A+ + P PPPP P PPPPP PPPPLP+ G Q PA PP P
Sbjct: 2490 KALADQQKAQQPAVAQPPPPQPQPPPPPQQPPPPLPQPQAAGS-----QPPAGPPAVQPQ 2544
Query: 1570 QQPLPQEEEVKAKRQRKSR 1588
QP PQ + + K++
Sbjct: 2545 PQPQPQTQPQPVQAPAKAQ 2563
Score = 55.5 bits (132), Expect = 4e-07
Identities = 34/100 (34%), Positives = 43/100 (43%), Gaps = 5/100 (5%)
Query: 1491 LSPLVLEPAASQDTIMATIEAVIHMAREAPPLPPPPPPPLPPPPPPPLPPPPPLPKTPRG 1550
++ L E A + +A + A PP P P PPP P PPPPLP P P
Sbjct: 2477 VASLRAERIAKEKKALADQQKAQQPAVAQPPPPQPQPPPPPQQPPPPLPQPQAAGSQPPA 2536
Query: 1551 GKRKHKPQAPAQPPQQSPPQQPLPQEEEVKAKRQRKSRGS 1590
G +PQ PQ P QP P + KA+ + GS
Sbjct: 2537 GPPAVQPQ-----PQPQPQTQPQPVQAPAKAQPAITTGGS 2571
Score = 43.9 bits (102), Expect = 0.001
Identities = 51/225 (22%), Positives = 85/225 (37%), Gaps = 31/225 (13%)
Query: 1364 PAAVDSVTIPPAPVLSLLAASAATSDAVGSSLKKRFKRREIEAIQCEVRKMCNYTKILST 1423
PA V PP V S + AT D V + + R + ++ N T + +
Sbjct: 2634 PAQVVHTQPPPRAVGS---PATATPDLVSMATTQGV--RAVTSVTASAVVTTNLTPVQTP 2688
Query: 1424 KKNLDHVNKILKAKRLQRQSKTGNN-----FVKKRRGRPRKQPTQFDEDSRDQMPVLEKC 1478
++L V ++ +A +Q KT ++++ + ++Q Q + + Q ++
Sbjct: 2689 ARSL--VPQVSQATGVQLPGKTITPAHFQLLRQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 2746
Query: 1479 IDLPSKRGQKPSLSPLVLEPAASQDTIMATIEAVIHMAREAPPLPPPPPPPLPPPPPPPL 1538
+ + Q P + PA + T E +I M ++ +PP PPPP PP
Sbjct: 2747 QTTTTSQVQVPQIQGQAQSPAQIKAVGKLTPEHLIKMQKQKLQMPPQPPPPQAQSAPP-- 2804
Query: 1539 PPPPPLPKTPRGGKRKHKPQAPAQPPQQSPPQQPLPQEEEVKAKR 1583
+P A Q PPQQ PQ V A R
Sbjct: 2805 -----------------QPTAQVQVQTSQPPQQQSPQLTTVTAPR 2832
>gi|210032580 SET domain containing 1B [Homo sapiens]
Length = 1923
Score = 61.6 bits (148), Expect = 6e-09
Identities = 35/88 (39%), Positives = 42/88 (47%), Gaps = 6/88 (6%)
Query: 1493 PLVLEPAASQDTIMATIEAVIHMAREA--PPLPPPPPPPLPPPP---PPPLPPPPPLPKT 1547
P+V+ P A+ + + + + PPLPPPPPPP P P PPPLPPPPP P
Sbjct: 659 PMVVTPGAAAVAAPSVLAPTLPLPPPPGFPPLPPPPPPPPPQPGFPMPPPLPPPPPPPPP 718
Query: 1548 PRGGKRKHKPQAPAQPPQQSPP-QQPLP 1574
P PA P PP PLP
Sbjct: 719 AHPAVTVPPPPLPAPPGVPPPPILPPLP 746
Score = 47.8 bits (112), Expect = 9e-05
Identities = 28/67 (41%), Positives = 36/67 (53%), Gaps = 7/67 (10%)
Query: 1524 PPPPPPLPPPPPPPLPPPPPLPKTPRGGKRKHKPQAPAQPPQQSPPQQPLPQEEEVKAKR 1583
P PPPPLPP PPPP PPPPP+ T K + Q P ++ P P ++E +
Sbjct: 1537 PAPPPPLPPQPPPP-PPPPPVEPTKLPFK-----ELDNQWPSEAIPPGPRGRDEVTEEYM 1590
Query: 1584 Q-RKSRG 1589
+ KSRG
Sbjct: 1591 ELAKSRG 1597
Score = 47.0 bits (110), Expect = 1e-04
Identities = 40/138 (28%), Positives = 54/138 (39%), Gaps = 38/138 (27%)
Query: 1457 PRKQPTQFDEDSRDQMPVLEKCIDLPSKRGQKPSLSPLVLEPAASQDTIMAT-------- 1508
P ++P+ DE P L ++ P+ + P EP SQ+ M
Sbjct: 1200 PEERPSMLDE------PPLPVGVEEPADSREPPE------EPGLSQEGAMLLSPEPPAKE 1247
Query: 1509 IEAVIHMAREAPP-------------LPPPPPPPLPPPPPPPLPPPPPLPKTPRGGKRKH 1555
+EA ++ E P LP P PPLPPP PP P PPP P+T
Sbjct: 1248 VEARPPLSPERAPEHDLEVEPEPPMMLPLPLQPPLPPPRPPRPPSPPPEPETTDAS---- 1303
Query: 1556 KPQAPAQP-PQQSPPQQP 1572
P P +P + PP P
Sbjct: 1304 HPSVPPEPLAEDHPPHTP 1321
Score = 45.8 bits (107), Expect = 3e-04
Identities = 45/176 (25%), Positives = 63/176 (35%), Gaps = 58/176 (32%)
Query: 1450 VKKRRGRPRKQPTQFDEDSRDQMPVLEKCIDLPSKRGQKPSL--SPLVLEPAASQDTIMA 1507
+K++ GRPR+ P +D P R + L+L P Q +
Sbjct: 1472 MKRKPGRPRRSPPSM------------LSLDGPLVRPPAGAALGRELLLLPGQPQTPVFP 1519
Query: 1508 TIE----AVIHMAREAPPLPPPPPPPLPPPPPPPLP---------------PPPPLPKTP 1548
+ + P PPPP PP PPPPPPP P P +P P
Sbjct: 1520 STHDPRTVTLDFRNAGIPAPPPPLPPQPPPPPPPPPVEPTKLPFKELDNQWPSEAIPPGP 1579
Query: 1549 RG---------------------GKRKHKPQA-PAQPPQQSPPQ---QPLPQEEEV 1579
RG K++H+ PA P+ SPPQ +P + EE+
Sbjct: 1580 RGRDEVTEEYMELAKSRGPWRRPPKKRHEDLVPPAGSPELSPPQPLFRPRSEFEEM 1635
Score = 39.3 bits (90), Expect = 0.031
Identities = 39/193 (20%), Positives = 82/193 (42%), Gaps = 20/193 (10%)
Query: 1186 LSERLSSADKELPLVSEKNKHKEKQKHQHSEAGHKASKNNFEVDTLSTLSLSDAQHWTQA 1245
LSE S ++E E + +E++ ++ + N + DT +LS+A
Sbjct: 1041 LSEEQESTEEE----EEAEEEEEEEDDDDDDSDDRDESENDDEDT----ALSEASE---- 1088
Query: 1246 KEKGDLSSEPVDSCTKRYSGSGGDGGSTRSENLDVFSEMNPSNDKWDSD-VSGSKRRSYE 1304
K++GD E S + + S+ S + SE +PS+ + + + V+ + E
Sbjct: 1089 KDEGDSDEEETVSIVTSKAEATSSSESSESSEFESSSESSPSSSEDEEEVVAREEEEEEE 1148
Query: 1305 GFGTYREKDIQAFKMNRKERSSYDSSMSPGMPSPHLKVDQTAVHSKNEGSVPTMMTRKKP 1364
E+ + + E+ +++++PG P+ VD + + + + ++P
Sbjct: 1149 EEEMVAEESMASAGPEDFEQDGEEAALAPGAPA----VDSLGMEEEVDIETEAVAPEERP 1204
Query: 1365 AAVDSVTIPPAPV 1377
+ +D PP PV
Sbjct: 1205 SMLDE---PPLPV 1214
Score = 36.6 bits (83), Expect = 0.20
Identities = 25/77 (32%), Positives = 29/77 (37%), Gaps = 11/77 (14%)
Query: 1520 PPLPPPPPPPLPPPPPPPLPPPPPLPKTPRGGK-----RKHKPQAPAQPPQQSPPQQP-- 1572
PPLPP P P PP PPPP GG+ +P P +S P P
Sbjct: 435 PPLPPAEPLAKEKPGTPPGPPPPDTNSMELGGRPTFGWSPEPCDSPGTPTLESSPAGPEK 494
Query: 1573 ----LPQEEEVKAKRQR 1585
L E+ K QR
Sbjct: 495 PHDSLDSRIEMLLKEQR 511
Score = 36.6 bits (83), Expect = 0.20
Identities = 121/587 (20%), Positives = 208/587 (35%), Gaps = 107/587 (18%)
Query: 78 EKWVAGDGLEEQEFSIKEANFTEGSLKLKIQTTKRAKKPPKNLENYICPPEIKITIKQSG 137
E W G+GL + + G+++L KR K+PP SG
Sbjct: 934 ESWGKGEGLGYEGLGLGIG--LRGAIRLPSFKVKR-KEPPDTTS--------------SG 976
Query: 138 DQKVSRAGKN-SKATKEEERSHSKKKLLTASDLAASDLKGFQPQAYERPQKHSTLHYDTG 196
DQK R + + +E ER + T +LA D KG + RP + L D+G
Sbjct: 977 DQKRLRPSTSVDEEDEESERERDRDMADTPCELAKRDPKGVGVR--RRPAR--PLELDSG 1032
Query: 197 LPQD----------FTGDTLKPKHQQKSSSQNHMDWSTNSDSGPVTQNCFISPESGRETA 246
+D T + + + +++ + D +S ++ +S S ++
Sbjct: 1033 GEEDEKESLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDESENDDEDTALSEASEKDEG 1092
Query: 247 STSKIPALEPVASFAKAQGKKGSAGNTWSQLSNNNKDLLLGGVAPSPSSHSSPAPPSSSA 306
+ + + V S A+A S+ ++ + S+ + +PS S
Sbjct: 1093 DSDEEETVSIVTSKAEATSSSESSESSEFESSSES--------SPSSSEDEEEVVAREEE 1144
Query: 307 ECNGLQPLV-------------DQDGGGTKEPPEPPTVGSKKKSSKKDVISQTIPNPDLD 353
E + +V +QDG P P V S + D+ ++ + +
Sbjct: 1145 EEEEEEEMVAEESMASAGPEDFEQDGEEAALAPGAPAVDSLGMEEEVDIETEAVAPEERP 1204
Query: 354 WVKN-------AQKAFDNTEGKRE-GYSADSAQEASP--------ARQNVSSASNPEND- 396
+ + ++ D+ E E G S + A SP AR +S PE+D
Sbjct: 1205 SMLDEPPLPVGVEEPADSREPPEEPGLSQEGAMLLSPEPPAKEVEARPPLSPERAPEHDL 1264
Query: 397 ----SSHVRITIPIKAPSLDPTNHKRK-----KRQSIKAVVEKIMPEKALASGITMSSEV 447
+ + +P++ P L P R + ++ A + PE LA +
Sbjct: 1265 EVEPEPPMMLPLPLQPP-LPPPRPPRPPSPPPEPETTDASHPSVPPEP-LAEDHPPHTPG 1322
Query: 448 VNRILSNSEGNKKDPRVPKLSKMIENESPSVGLETG----------GNAEKVIPGGVSKP 497
+ L+ S+ + P P + S + L + + + GG+ P
Sbjct: 1323 LCGSLAKSQSTETVPATPGGEPPLSGGSSGLSLSSPQVPGSPFSYPAPSPSLSSGGL--P 1380
Query: 498 RKPPMVMT-PPTCTDHSPSRKLPEIQHPKFAAKRRWTCSKPKPSTMLREAVMATSDKLML 556
R P + PT ++ S LP P RR S P S +L E + L L
Sbjct: 1381 RTPGRDFSFTPTFSEPSGPLLLPVCPLP---TGRRDERSGPLASPVLLETGLPLPLPLPL 1437
Query: 557 EPPSAYPI---------TPSSPLYTNTDSLTVITPVKKKRGRPKKQP 594
P A P TP PL + P+K+K GRP++ P
Sbjct: 1438 PLPLALPAVLRAQARAPTPLPPLLP-APLASCPPPMKRKPGRPRRSP 1483
Score = 32.0 bits (71), Expect = 4.9
Identities = 30/106 (28%), Positives = 41/106 (38%), Gaps = 16/106 (15%)
Query: 1473 PVLEKCIDLPSKRGQK---PSLSPLVLE-----PAASQDTIMATIEAVIHMAREAPPLPP 1524
P+L LP+ R + P SP++LE P + + AV+ AP
Sbjct: 1399 PLLLPVCPLPTGRRDERSGPLASPVLLETGLPLPLPLPLPLPLALPAVLRAQARAPT--- 1455
Query: 1525 PPPPPLPPPPPPPLPP-PPPLPKTPRGGKRKHKPQAPAQPPQQSPP 1569
PLPP P PL PPP+ + P +R P PP
Sbjct: 1456 ----PLPPLLPAPLASCPPPMKRKPGRPRRSPPSMLSLDGPLVRPP 1497
Score = 31.6 bits (70), Expect = 6.4
Identities = 22/89 (24%), Positives = 37/89 (41%), Gaps = 4/89 (4%)
Query: 1486 GQKPSLSP--LVLEPAASQDTIMATIEAVIHMAREAPPLPPPPPPPLPPPPPPPLPPPPP 1543
G++ +L+P ++ ++ + EAV E P + PP P+ P PP
Sbjct: 1170 GEEAALAPGAPAVDSLGMEEEVDIETEAVA--PEERPSMLDEPPLPVGVEEPADSREPPE 1227
Query: 1544 LPKTPRGGKRKHKPQAPAQPPQQSPPQQP 1572
P + G P+ PA+ + PP P
Sbjct: 1228 EPGLSQEGAMLLSPEPPAKEVEARPPLSP 1256
>gi|153792074 proline rich 12 [Homo sapiens]
Length = 2036
Score = 61.2 bits (147), Expect = 8e-09
Identities = 76/339 (22%), Positives = 125/339 (36%), Gaps = 46/339 (13%)
Query: 1244 QAKEKGDLSSEPVD------SCTKRYSGSGGDGGSTRSENLDVFSEMNPSNDKWDSDVSG 1297
+A+E G EP+ S K G G G S + + + +K ++ +
Sbjct: 1210 KAEEAGGTRLEPLKPLKIKLSVPKAGEGLGTSSGDAISGTDHNSLDSSLTREKIEAKIKE 1269
Query: 1298 SKRRSYEGFGTYREKDIQAFKMNRKERSSYDSSMSPGMPSPHLKVDQTAVHSKNEGSVPT 1357
+ + E + + K ++ Y + ++P + P SVP
Sbjct: 1270 VEEKQPEMKSGFMASFLDFLKSGKRHPPLYQAGLTPPLSPP----------KSVPPSVPA 1319
Query: 1358 MMTRKKPAAVDSVTIPPAPVLSLL--AASAATSDAVGSSLKKRFKRREIEAIQCEVRKMC 1415
+ +P A +V PP L A AA S+ +G KR + E ++ + +
Sbjct: 1320 RGLQPQPPATPAVPHPPPSGAFGLGGALEAAESEGLGLGCPSPCKRLD-EELKRNLETLP 1378
Query: 1416 NYTKILSTKKNLDHVNKILKAKRLQRQSKTGNNFVKKRRGRPRKQPTQFDEDSRDQMPVL 1475
+++ D + + K + LQ + + P P D + D P+
Sbjct: 1379 SFSS--------DEEDSVAKNRDLQESISSA---ISALDDPPLAGPK--DTSTPDGPPL- 1424
Query: 1476 EKCIDLPSKRGQKPSLSPLVLEPAASQDTIMATIEAVIHMAREAPPLPPPPPPPLPPPPP 1535
+ P PL P+A+ + T E + + + PP PPP P P P PPP
Sbjct: 1425 -------APAAAVPGPPPLPGLPSANSN---GTPEPPL-LEEKPPPTPPPAPTPQPQPPP 1473
Query: 1536 PPLPPPPPLPKTPRGGKRKHKPQAPAQPPQQSPPQQPLP 1574
PP PP P LP P P +P PP PP +P
Sbjct: 1474 PPPPPQPALPSPP--PLVAPTPSSPPPPPLPPPPPPAMP 1510
Score = 57.8 bits (138), Expect = 8e-08
Identities = 25/50 (50%), Positives = 28/50 (56%), Gaps = 1/50 (2%)
Query: 1519 APPLPPPPPPPLPPPPPPPLPPPPPLPKTPRGGKRKHKPQAPAQPPQQSP 1568
AP PPPPPLPPPPPP +P PPP P P P+ PA P + P
Sbjct: 1490 APTPSSPPPPPLPPPPPPAMPSPPP-PPPPAAAPLAAPPEEPAAPSPEDP 1538
Score = 54.3 bits (129), Expect = 9e-07
Identities = 24/54 (44%), Positives = 28/54 (51%)
Query: 1520 PPLPPPPPPPLPPPPPPPLPPPPPLPKTPRGGKRKHKPQAPAQPPQQSPPQQPL 1573
P PPPPP P PPPP P PPPPP P +P AP+ + P +PL
Sbjct: 1493 PSSPPPPPLPPPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPSPEDPELPDTRPL 1546
Score = 44.7 bits (104), Expect = 7e-04
Identities = 29/85 (34%), Positives = 38/85 (44%), Gaps = 9/85 (10%)
Query: 1489 PSLSPLVLEPAASQDTIMATIEAVIHMAREAPPLPPPPPPPLPPPPPPPLPPPPPLPKTP 1548
P L P VL A S + + +H+ L P P PPPPP PPPPP+P
Sbjct: 799 PQLLPSVLSHAPSPSPSASKVG--VHL------LEPATRDGAPQPPPPPPPPPPPMPLQL 850
Query: 1549 RGGKRKHKPQAPAQPPQQSPPQQPL 1573
R H + PA P + P++ L
Sbjct: 851 EAHLRSHGLE-PAAPSPRLRPEESL 874
Score = 41.2 bits (95), Expect = 0.008
Identities = 34/129 (26%), Positives = 43/129 (33%), Gaps = 35/129 (27%)
Query: 1498 PAASQDTIMATIEAVIHMAREAPPL-------PPPPPPP--------------------- 1529
P +T +V+H A L PPPPPP
Sbjct: 732 PERGGETPEGLATSVVHYGAGAKELGAFLQKSPPPPPPTAQSTQPTPHGLLLEAGGPDLP 791
Query: 1530 --LPPPPPPPLPP-----PPPLPKTPRGGKRKHKPQAPAQPPQQSPPQQPLPQEEEVKAK 1582
LPPPPP LP P P P + G +P PQ PP P P ++ +
Sbjct: 792 LVLPPPPPQLLPSVLSHAPSPSPSASKVGVHLLEPATRDGAPQPPPPPPPPPPPMPLQLE 851
Query: 1583 RQRKSRGSE 1591
+S G E
Sbjct: 852 AHLRSHGLE 860
Score = 40.0 bits (92), Expect = 0.018
Identities = 19/62 (30%), Positives = 34/62 (54%), Gaps = 9/62 (14%)
Query: 1534 PPPPLPPPPPLPKTPRGGKRKHKPQAPAQPPQQSPPQQPLPQEE------EVKAKRQRKS 1587
PPP P PPP P+TP ++ + P Q P+ + P+ P P++ E + ++++ +
Sbjct: 1692 PPPKAPAPPPKPETP---EKTTSEKPPEQTPETAMPEPPAPEKPSLLRPVEKEKEKEKVT 1748
Query: 1588 RG 1589
RG
Sbjct: 1749 RG 1750
Score = 37.7 bits (86), Expect = 0.090
Identities = 32/102 (31%), Positives = 39/102 (38%), Gaps = 14/102 (13%)
Query: 1489 PSLSPLVLEPAASQDTIMATIEAVIHMAREAPPLPP-----PPPPPLPPPPPPPLPPP-P 1542
PS S + A + +I + I + P P P PPL P P PPP P
Sbjct: 1378 PSFSSDEEDSVAKNRDLQESISSAISALDDPPLAGPKDTSTPDGPPLAPAAAVPGPPPLP 1437
Query: 1543 PLPK-----TPRGGKRKHKP---QAPAQPPQQSPPQQPLPQE 1576
LP TP + KP PA PQ PP P P +
Sbjct: 1438 GLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQ 1479
Score = 37.4 bits (85), Expect = 0.12
Identities = 18/56 (32%), Positives = 23/56 (41%)
Query: 1486 GQKPSLSPLVLEPAASQDTIMATIEAVIHMAREAPPLPPPPPPPLPPPPPPPLPPP 1541
G P L L+P + + + + P PPPPP PPPPP P P
Sbjct: 1000 GAGPETPGLGLDPNKPPELPSTVNAEPLGLIQSGPHQAAPPPPPPPPPPPAPASEP 1055
Score = 37.0 bits (84), Expect = 0.15
Identities = 14/25 (56%), Positives = 15/25 (60%)
Query: 1527 PPPLPPPPPPPLPPPPPLPKTPRGG 1551
P PPPPPP PPPP P+GG
Sbjct: 1034 PHQAAPPPPPPPPPPPAPASEPKGG 1058
Score = 35.0 bits (79), Expect = 0.58
Identities = 23/76 (30%), Positives = 29/76 (38%), Gaps = 12/76 (15%)
Query: 1522 LPPPPPPPLPPPPPPPLPPPPPLP---------KTPRGGKRKHKPQA---PAQPPQQSPP 1569
L P PP P PP P PPP LP + PQ P PP
Sbjct: 219 LGPAQTPPYRPGPPDPPPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGAAPGPPPP 278
Query: 1570 QQPLPQEEEVKAKRQR 1585
++ LP+++ V QR
Sbjct: 279 ERALPRQDTVIKHYQR 294
Score = 33.9 bits (76), Expect = 1.3
Identities = 23/74 (31%), Positives = 33/74 (44%), Gaps = 5/74 (6%)
Query: 1519 APPLPPPPPPPLPPPPPPPLPPPPPLPKTPRGGKRKHKPQAPAQPPQQSPPQQPLPQEEE 1578
APP P PPP P P PP +TP +P AP +P P ++ +E+E
Sbjct: 1691 APPPKAPAPPPKPETPEKTTSEKPP-EQTPE--TAMPEPPAPEKPSLLRPVEK--EKEKE 1745
Query: 1579 VKAKRQRKSRGSES 1592
+ +R RG +
Sbjct: 1746 KVTRGERPLRGERA 1759
Score = 32.7 bits (73), Expect = 2.9
Identities = 57/215 (26%), Positives = 81/215 (37%), Gaps = 33/215 (15%)
Query: 585 KKRGRPKKQPLLTVETIHEGTSTSPVSPISREFPGTKK-RKRRRNLAKLAQLVPGED-KP 642
+ RGRP+ +PL T ++++P G KK R R R + A+ G +P
Sbjct: 1169 RPRGRPRIRPLEVPTTAGPASASTPTD-------GAKKPRGRGRGRGRKAEEAGGTRLEP 1221
Query: 643 MSEMKFHKKVGKLGV-LDKKTIKTINKMKTLKRKNILNQILSCSSSVALKAKAPPETSPG 701
+ +K V K G L + I+ N L+ L+ + K K E P
Sbjct: 1222 LKPLKIKLSVPKAGEGLGTSSGDAISGTD----HNSLDSSLT-REKIEAKIKEVEEKQP- 1275
Query: 702 AAAIESKLGKQINVSKRGTIYIGKKRGRKPRAELPPPSEEPKTAIKHPRPVSSQPDVPAV 761
E K G S + GK+ +A L PP PK S P VPA
Sbjct: 1276 ----EMKSG--FMASFLDFLKSGKRHPPLYQAGLTPPLSPPK---------SVPPSVPA- 1319
Query: 762 PSNFQSLVASSPAAMHPLSTQLGGSNGNLSPASTE 796
Q ++PA HP + G G L A +E
Sbjct: 1320 -RGLQPQPPATPAVPHPPPSGAFGLGGALEAAESE 1353
Score = 32.0 bits (71), Expect = 4.9
Identities = 24/75 (32%), Positives = 25/75 (33%), Gaps = 20/75 (26%)
Query: 1523 PPPPPPPLPPPPP----------PPLP-------PPPPLPKTPRG---GKRKHKPQAPAQ 1562
PPP PP P P P P PP LP T G + P A
Sbjct: 980 PPPGPPAYDPYGPYCPGRASGAGPETPGLGLDPNKPPELPSTVNAEPLGLIQSGPHQAAP 1039
Query: 1563 PPQQSPPQQPLPQEE 1577
PP PP P P E
Sbjct: 1040 PPPPPPPPPPAPASE 1054
Score = 32.0 bits (71), Expect = 4.9
Identities = 73/331 (22%), Positives = 111/331 (33%), Gaps = 48/331 (14%)
Query: 289 VAPSPSSHSSPAPPSSSAECNGLQPLVDQDGGGTKEPPEPPTVGSKKKSSKKDVISQTIP 348
VAP+PSS P PP P PP PP + + ++ + +
Sbjct: 1489 VAPTPSS---PPPPPLPPPPPPAMP---------SPPPPPPPAAAPLAAPPEEPAAPSPE 1536
Query: 349 NPDLDWVKNAQKAFDNTEGKREGYSADSAQEASPARQNVSSASNPENDSSHVRIT-IPIK 407
+P+L + A K++ +A + A ++ E D +R IP
Sbjct: 1537 DPELPDTRPLHLA------KKQETAAVCGETDEEAGESGGEGIFRERDEFVIRAEDIPSL 1590
Query: 408 APSLDPTNHKRKKRQSIKAVVEKIMPEK--------ALASGITMSSEVVNR-------IL 452
+L + KA+++K PE A ++ + + NR L
Sbjct: 1591 KLALQTGREPPPIWRVQKALLQKFTPEIKDGQRQFCATSNYLGYFGDAKNRYQRLYVKFL 1650
Query: 453 SNSEGNKKDPRVPKLSKMIENESPSVGLETGGNAEKVIPGGVSK------PRKPPMVMTP 506
N NKKD ++ P V + G A+ + G S P PP TP
Sbjct: 1651 ENV--NKKD--YVRVCARKPWHRPPVPVRRSGQAKNPVSAGGSSAPPPKAPAPPPKPETP 1706
Query: 507 PTCTDHSPSRKLPEIQHPKFAAKRRWTCSKPKPSTMLREAVMATSDKLMLE-PPSAYPIT 565
T P + PE P+ A + + +P +E V L E S
Sbjct: 1707 EKTTSEKPPEQTPETAMPEPPAPEKPSLLRPVEKEKEKEKVTRGERPLRGERATSGRQTR 1766
Query: 566 PSSPLYTN---TDSLTVITPVKKKRGRPKKQ 593
P L T T L P K K P K+
Sbjct: 1767 PERSLATGQPATSRLPKARPTKVKAEPPPKK 1797
>gi|149944526 additional sex combs like 3 [Homo sapiens]
Length = 2248
Score = 61.2 bits (147), Expect = 8e-09
Identities = 32/77 (41%), Positives = 37/77 (48%), Gaps = 4/77 (5%)
Query: 1498 PAASQDTIMATIEAVIHMAREAPPLPPPPPPP----LPPPPPPPLPPPPPLPKTPRGGKR 1553
P D + T + + A PP PPPPPPP LPPPPPPP P PPPLP +
Sbjct: 1995 PMKEGDEVGGTAHTMPNKALVHPPPPPPPPPPPPLALPPPPPPPPPLPPPLPNAEVPSDQ 2054
Query: 1554 KHKPQAPAQPPQQSPPQ 1570
K P + S PQ
Sbjct: 2055 KQPPVTMETTKRLSWPQ 2071
Score = 45.4 bits (106), Expect = 4e-04
Identities = 24/61 (39%), Positives = 26/61 (42%), Gaps = 21/61 (34%)
Query: 1524 PPPPPPLPPPPPPPLPPPPPLPKTPRGGKRKHKPQAPAQPPQQSPPQQPLPQEEEVKAKR 1583
PPPPPP PPPPP LPPPPP P P PLP E ++
Sbjct: 2017 PPPPPPPPPPPPLALPPPPPPPP---------------------PLPPPLPNAEVPSDQK 2055
Query: 1584 Q 1584
Q
Sbjct: 2056 Q 2056
>gi|150378543 MYST histone acetyltransferase (monocytic leukemia) 3
[Homo sapiens]
Length = 2004
Score = 60.5 bits (145), Expect = 1e-08
Identities = 30/84 (35%), Positives = 41/84 (48%), Gaps = 4/84 (4%)
Query: 1495 VLEPAASQDTIMATIEAVIHMAREAPPL----PPPPPPPLPPPPPPPLPPPPPLPKTPRG 1550
+++ ++ Q +I++ E PP PPPPPP P PPPP P P P P P+
Sbjct: 1618 MMQQSSVQPAANCSIKSPQSCVVERPPSNQQQQPPPPPPQQPQPPPPQPQPAPQPPPPQQ 1677
Query: 1551 GKRKHKPQAPAQPPQQSPPQQPLP 1574
++ P QPP PPQQ P
Sbjct: 1678 QPQQQPQPQPQQPPPPPPPQQQPP 1701
Score = 51.2 bits (121), Expect = 8e-06
Identities = 24/57 (42%), Positives = 29/57 (50%), Gaps = 2/57 (3%)
Query: 1523 PPPPPPPLPPPPPP--PLPPPPPLPKTPRGGKRKHKPQAPAQPPQQSPPQQPLPQEE 1577
PP PPPPPP P PPPP P+ + +PQ QP Q PP P PQ++
Sbjct: 1643 PPSNQQQQPPPPPPQQPQPPPPQPQPAPQPPPPQQQPQQQPQPQPQQPPPPPPPQQQ 1699
Score = 35.8 bits (81), Expect = 0.34
Identities = 19/61 (31%), Positives = 24/61 (39%), Gaps = 19/61 (31%)
Query: 1524 PPPPPPLPPPPPPPLPPPPPLPKTPRGGKRKHKPQAPAQPPQQSPPQQPLPQEEEVKAKR 1583
PP PPPPPP P PP PPQ P QP P +++ + +
Sbjct: 1643 PPSNQQQQPPPPPPQQPQPP-------------------PPQPQPAPQPPPPQQQPQQQP 1683
Query: 1584 Q 1584
Q
Sbjct: 1684 Q 1684
Score = 34.3 bits (77), Expect = 0.99
Identities = 16/33 (48%), Positives = 16/33 (48%), Gaps = 9/33 (27%)
Query: 1521 PLPPPP---------PPPLPPPPPPPLPPPPPL 1544
P PPPP P P PPPPPP PPL
Sbjct: 1670 PQPPPPQQQPQQQPQPQPQQPPPPPPPQQQPPL 1702
>gi|150378463 MYST histone acetyltransferase (monocytic leukemia) 3
[Homo sapiens]
Length = 2004
Score = 60.5 bits (145), Expect = 1e-08
Identities = 30/84 (35%), Positives = 41/84 (48%), Gaps = 4/84 (4%)
Query: 1495 VLEPAASQDTIMATIEAVIHMAREAPPL----PPPPPPPLPPPPPPPLPPPPPLPKTPRG 1550
+++ ++ Q +I++ E PP PPPPPP P PPPP P P P P P+
Sbjct: 1618 MMQQSSVQPAANCSIKSPQSCVVERPPSNQQQQPPPPPPQQPQPPPPQPQPAPQPPPPQQ 1677
Query: 1551 GKRKHKPQAPAQPPQQSPPQQPLP 1574
++ P QPP PPQQ P
Sbjct: 1678 QPQQQPQPQPQQPPPPPPPQQQPP 1701
Score = 51.2 bits (121), Expect = 8e-06
Identities = 24/57 (42%), Positives = 29/57 (50%), Gaps = 2/57 (3%)
Query: 1523 PPPPPPPLPPPPPP--PLPPPPPLPKTPRGGKRKHKPQAPAQPPQQSPPQQPLPQEE 1577
PP PPPPPP P PPPP P+ + +PQ QP Q PP P PQ++
Sbjct: 1643 PPSNQQQQPPPPPPQQPQPPPPQPQPAPQPPPPQQQPQQQPQPQPQQPPPPPPPQQQ 1699
Score = 35.8 bits (81), Expect = 0.34
Identities = 19/61 (31%), Positives = 24/61 (39%), Gaps = 19/61 (31%)
Query: 1524 PPPPPPLPPPPPPPLPPPPPLPKTPRGGKRKHKPQAPAQPPQQSPPQQPLPQEEEVKAKR 1583
PP PPPPPP P PP PPQ P QP P +++ + +
Sbjct: 1643 PPSNQQQQPPPPPPQQPQPP-------------------PPQPQPAPQPPPPQQQPQQQP 1683
Query: 1584 Q 1584
Q
Sbjct: 1684 Q 1684
Score = 34.3 bits (77), Expect = 0.99
Identities = 16/33 (48%), Positives = 16/33 (48%), Gaps = 9/33 (27%)
Query: 1521 PLPPPP---------PPPLPPPPPPPLPPPPPL 1544
P PPPP P P PPPPPP PPL
Sbjct: 1670 PQPPPPQQQPQQQPQPQPQQPPPPPPPQQQPPL 1702
>gi|150378493 MYST histone acetyltransferase (monocytic leukemia) 3
[Homo sapiens]
Length = 2004
Score = 60.5 bits (145), Expect = 1e-08
Identities = 30/84 (35%), Positives = 41/84 (48%), Gaps = 4/84 (4%)
Query: 1495 VLEPAASQDTIMATIEAVIHMAREAPPL----PPPPPPPLPPPPPPPLPPPPPLPKTPRG 1550
+++ ++ Q +I++ E PP PPPPPP P PPPP P P P P P+
Sbjct: 1618 MMQQSSVQPAANCSIKSPQSCVVERPPSNQQQQPPPPPPQQPQPPPPQPQPAPQPPPPQQ 1677
Query: 1551 GKRKHKPQAPAQPPQQSPPQQPLP 1574
++ P QPP PPQQ P
Sbjct: 1678 QPQQQPQPQPQQPPPPPPPQQQPP 1701
Score = 51.2 bits (121), Expect = 8e-06
Identities = 24/57 (42%), Positives = 29/57 (50%), Gaps = 2/57 (3%)
Query: 1523 PPPPPPPLPPPPPP--PLPPPPPLPKTPRGGKRKHKPQAPAQPPQQSPPQQPLPQEE 1577
PP PPPPPP P PPPP P+ + +PQ QP Q PP P PQ++
Sbjct: 1643 PPSNQQQQPPPPPPQQPQPPPPQPQPAPQPPPPQQQPQQQPQPQPQQPPPPPPPQQQ 1699
Score = 35.8 bits (81), Expect = 0.34
Identities = 19/61 (31%), Positives = 24/61 (39%), Gaps = 19/61 (31%)
Query: 1524 PPPPPPLPPPPPPPLPPPPPLPKTPRGGKRKHKPQAPAQPPQQSPPQQPLPQEEEVKAKR 1583
PP PPPPPP P PP PPQ P QP P +++ + +
Sbjct: 1643 PPSNQQQQPPPPPPQQPQPP-------------------PPQPQPAPQPPPPQQQPQQQP 1683
Query: 1584 Q 1584
Q
Sbjct: 1684 Q 1684
Score = 34.3 bits (77), Expect = 0.99
Identities = 16/33 (48%), Positives = 16/33 (48%), Gaps = 9/33 (27%)
Query: 1521 PLPPPP---------PPPLPPPPPPPLPPPPPL 1544
P PPPP P P PPPPPP PPL
Sbjct: 1670 PQPPPPQQQPQQQPQPQPQQPPPPPPPQQQPPL 1702
>gi|19923345 RNA binding motif protein 12 [Homo sapiens]
Length = 932
Score = 60.5 bits (145), Expect = 1e-08
Identities = 32/88 (36%), Positives = 40/88 (45%), Gaps = 2/88 (2%)
Query: 1489 PSLSPLVLEPAASQDTIMATIEAVIHMAREAPPLPPPPPPPLPPPPP--PPLPPPPPLPK 1546
P+ S V A+ +T+ I PP+P PP P+PPP P PP+PP PP+P
Sbjct: 169 PTFSSTVPSTASPMNTVPPPPIPPIPAMPSLPPMPSIPPIPVPPPVPTLPPVPPVPPIPP 228
Query: 1547 TPRGGKRKHKPQAPAQPPQQSPPQQPLP 1574
P P PP PP PLP
Sbjct: 229 VPSVPPMTPLPPMSGMPPLNPPPVAPLP 256
Score = 35.8 bits (81), Expect = 0.34
Identities = 27/69 (39%), Positives = 31/69 (44%), Gaps = 11/69 (15%)
Query: 1489 PSLSPLVLEPAASQDTIMATIEAVIHMAREAPPLPP----PPPPPLPP-PPPPPLPPPP- 1542
PSL P+ P + T+ V PP+PP PP PLPP PPL PPP
Sbjct: 197 PSLPPMPSIPPIPVPPPVPTLPPV----PPVPPIPPVPSVPPMTPLPPMSGMPPLNPPPV 252
Query: 1543 -PLPKTPRG 1550
PLP G
Sbjct: 253 APLPAGMNG 261
>gi|23510462 RNA binding motif protein 12 [Homo sapiens]
Length = 932
Score = 60.5 bits (145), Expect = 1e-08
Identities = 32/88 (36%), Positives = 40/88 (45%), Gaps = 2/88 (2%)
Query: 1489 PSLSPLVLEPAASQDTIMATIEAVIHMAREAPPLPPPPPPPLPPPPP--PPLPPPPPLPK 1546
P+ S V A+ +T+ I PP+P PP P+PPP P PP+PP PP+P
Sbjct: 169 PTFSSTVPSTASPMNTVPPPPIPPIPAMPSLPPMPSIPPIPVPPPVPTLPPVPPVPPIPP 228
Query: 1547 TPRGGKRKHKPQAPAQPPQQSPPQQPLP 1574
P P PP PP PLP
Sbjct: 229 VPSVPPMTPLPPMSGMPPLNPPPVAPLP 256
Score = 35.8 bits (81), Expect = 0.34
Identities = 27/69 (39%), Positives = 31/69 (44%), Gaps = 11/69 (15%)
Query: 1489 PSLSPLVLEPAASQDTIMATIEAVIHMAREAPPLPP----PPPPPLPP-PPPPPLPPPP- 1542
PSL P+ P + T+ V PP+PP PP PLPP PPL PPP
Sbjct: 197 PSLPPMPSIPPIPVPPPVPTLPPV----PPVPPIPPVPSVPPMTPLPPMSGMPPLNPPPV 252
Query: 1543 -PLPKTPRG 1550
PLP G
Sbjct: 253 APLPAGMNG 261
>gi|126090663 zinc finger homeodomain 4 [Homo sapiens]
Length = 3571
Score = 60.1 bits (144), Expect = 2e-08
Identities = 37/103 (35%), Positives = 45/103 (43%), Gaps = 10/103 (9%)
Query: 1489 PSLSPLVLEPAASQDTIMATIEAVIHMAREAPPLPPPPPPPLPPPPPPPLPPPPPLPKTP 1548
P P L PA Q + M ++ ++ PP PPPP PPPPPPP PPPPP P P
Sbjct: 1960 PPPPPPPLPPAPPQPSSMGPVKIPNTVSTPLQAPPPTPPPPPPPPPPPPPPPPPPPPSAP 2019
Query: 1549 RGGKRKHKPQAPAQP-----PQQSPPQQP-----LPQEEEVKA 1581
+ P P P Q P P LPQ + + A
Sbjct: 2020 PQVQLPVSLDLPLFPSIMMQPVQHPALPPQLALQLPQMDALSA 2062
Score = 57.8 bits (138), Expect = 8e-08
Identities = 32/77 (41%), Positives = 33/77 (42%), Gaps = 27/77 (35%)
Query: 1518 EAPPLPPPPP--PPLPPPP------------------PPPLPPPPPLPKTPRGGKRKHKP 1557
E PP PPPPP PP PP P PPP PPPPP P P P
Sbjct: 1956 ETPPPPPPPPPLPPAPPQPSSMGPVKIPNTVSTPLQAPPPTPPPPPPPPPP-------PP 2008
Query: 1558 QAPAQPPQQSPPQQPLP 1574
P PP +PPQ LP
Sbjct: 2009 PPPPPPPPSAPPQVQLP 2025
Score = 56.6 bits (135), Expect = 2e-07
Identities = 30/73 (41%), Positives = 34/73 (46%), Gaps = 5/73 (6%)
Query: 1507 ATIEAVIHMAREA-----PPLPPPPPPPLPPPPPPPLPPPPPLPKTPRGGKRKHKPQAPA 1561
A +E REA P P P P PPPPPPPLPP PP P + K + P
Sbjct: 1931 AALEKFARQYREAYDKLYPISPSSPETPPPPPPPPPLPPAPPQPSSMGPVKIPNTVSTPL 1990
Query: 1562 QPPQQSPPQQPLP 1574
Q P +PP P P
Sbjct: 1991 QAPPPTPPPPPPP 2003
Score = 48.1 bits (113), Expect = 7e-05
Identities = 23/73 (31%), Positives = 36/73 (49%)
Query: 1522 LPPPPPPPLPPPPPPPLPPPPPLPKTPRGGKRKHKPQAPAQPPQQSPPQQPLPQEEEVKA 1581
L P PL PPPP PPPPP P + G++ + ++ Q P + +EEE++A
Sbjct: 3105 LSSAPTKPLLQTPPPPPPPPPPPPSSSLSGQQTEQQNKESEKKQTKPNKVKKIKEEELEA 3164
Query: 1582 KRQRKSRGSESEV 1594
+ K E ++
Sbjct: 3165 TKPEKHPKKEEKI 3177
Score = 37.4 bits (85), Expect = 0.12
Identities = 31/134 (23%), Positives = 45/134 (33%), Gaps = 15/134 (11%)
Query: 1451 KKRRGRPRKQPTQFDEDSRDQMPVLEKCIDLPSKRGQKPSLSPLVLEPAASQDTIMATIE 1510
KK+ + Q + + D M ++ + + + PAAS + +T
Sbjct: 2287 KKQCYKDEDDDAQDESQTEDSMDATDQVVYKHCTVSGQTDAAKNAAAPAASSGSGTST-- 2344
Query: 1511 AVIHMAREAPPLPPPPPPPLPPPPPPPLPPPPPLPKTPRGGKRKHKPQAPAQPPQQSPPQ 1570
P +P P P P P P P P P + KP P PPQ
Sbjct: 2345 ---------PLIPSPKPEPEKTSPKPEYPAEKPKQSDPSPPSQGTKPALPLASTSSDPPQ 2395
Query: 1571 ----QPLPQEEEVK 1580
QP PQ + K
Sbjct: 2396 ASTAQPQPQPQPPK 2409
Score = 31.6 bits (70), Expect = 6.4
Identities = 23/98 (23%), Positives = 37/98 (37%), Gaps = 8/98 (8%)
Query: 1482 PSKRGQKPSLSPLVLEPAASQDTIMATIEAVIHMAREAPPLPPPP--PPPLP------PP 1533
P+ + +PL+ P + E +++ P PP P LP P
Sbjct: 2334 PAASSGSGTSTPLIPSPKPEPEKTSPKPEYPAEKPKQSDPSPPSQGTKPALPLASTSSDP 2393
Query: 1534 PPPPLPPPPPLPKTPRGGKRKHKPQAPAQPPQQSPPQQ 1571
P P P P+ P+ + +P + +Q P S P Q
Sbjct: 2394 PQASTAQPQPQPQPPKQPQLIGRPPSASQTPVPSSPLQ 2431
>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
sapiens]
Length = 2715
Score = 60.1 bits (144), Expect = 2e-08
Identities = 39/143 (27%), Positives = 63/143 (44%), Gaps = 6/143 (4%)
Query: 1458 RKQPTQFDEDSRDQMPVLEKCIDLPSKRGQKPSLSPLVLEPAASQDTIMATIEAVIHMAR 1517
+KQ + D++ ++ EK D + ++ +++ ++ A ++ +
Sbjct: 355 KKQEQKLDDEEEEKKEEEEK--DKEGEEKEERAVAEEMMPAAEKEEAKLPPPPLTPPAPS 412
Query: 1518 EAPPLPPP---PPPPL-PPPPPPPLPPPPPLPKTPRGGKRKHKPQAPAQPPQQSPPQQPL 1573
PPLPPP PPPPL PPPPPP PPP P P P + + + P P S +
Sbjct: 413 PPPPLPPPSTSPPPPLCPPPPPPVSPPPLPSPPPPPAQEEQEESPPPVVPATCSRKRGRP 472
Query: 1574 PQEEEVKAKRQRKSRGSESEVLP 1596
P +A+R+ G E P
Sbjct: 473 PLTPSQRAEREAARAGPEGTSPP 495
Score = 45.4 bits (106), Expect = 4e-04
Identities = 22/62 (35%), Positives = 28/62 (45%), Gaps = 11/62 (17%)
Query: 1525 PPPPPLPPPPPPPLPPPPPLPKTPRGGKRKHKPQAPAQ-----------PPQQSPPQQPL 1573
PPPPP PPPPP P PPP P + R + P++ PP P+ P
Sbjct: 619 PPPPPAPPPPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPEAPE 678
Query: 1574 PQ 1575
P+
Sbjct: 679 PE 680
Score = 44.7 bits (104), Expect = 7e-04
Identities = 40/150 (26%), Positives = 51/150 (34%), Gaps = 36/150 (24%)
Query: 1450 VKKRRGRPRKQPTQFDEDSRDQMPVLEKCIDLPSKRGQKPSLSPLVLEPAASQDTIMATI 1509
V R R K P +F ++ + P +E P R + P+ EPA A
Sbjct: 532 VSARSSRVIKTPRRFMDEDPPKPPKVEVS---PVLRPPITTSPPVPQEPAPVPSPPRA-- 586
Query: 1510 EAVIHMAREAPPLPPPPPPPLPP--------------------PPPPPLPPPPPLPKTPR 1549
P PP P PLP PPPPP PPPPP P P
Sbjct: 587 -----------PTPPSTPVPLPEKRRSILREPTFRWTSLTRELPPPPPAPPPPPAPSPPP 635
Query: 1550 GGKRKHKPQAPAQPPQQSPPQQPLPQEEEV 1579
+ + PQ +P + L E V
Sbjct: 636 APATSSRRPLLLRAPQFTPSEAHLKIYESV 665
Score = 40.8 bits (94), Expect = 0.011
Identities = 26/80 (32%), Positives = 31/80 (38%), Gaps = 14/80 (17%)
Query: 1520 PPL---PPPPPPPLPPPPPPPLPPPPPLPKTPRGGKRKHKPQAPA----------QPPQQ 1566
PP+ PP P P P P PP P PP P P KR+ + P PP
Sbjct: 565 PPITTSPPVPQEPAPVPSPPRAPTPPSTP-VPLPEKRRSILREPTFRWTSLTRELPPPPP 623
Query: 1567 SPPQQPLPQEEEVKAKRQRK 1586
+PP P P A R+
Sbjct: 624 APPPPPAPSPPPAPATSSRR 643
Score = 37.7 bits (86), Expect = 0.090
Identities = 28/99 (28%), Positives = 39/99 (39%), Gaps = 25/99 (25%)
Query: 1487 QKPSLSPLVLEPAASQDTIM-ATIEAVIHMAREAPPLPPPPPPPL-------PPPPP--- 1535
++P L P + A + T+ + V+ + P PPPPPPPL P PP
Sbjct: 2216 KQPPLPPTISPTAPTSWTLPPGPLLGVLPVVGVVRPAPPPPPPPLTLVLSSGPASPPRQA 2275
Query: 1536 -------------PPLPPPPPLPKTPRGGK-RKHKPQAP 1560
PP PPP P+ G+ + PQ P
Sbjct: 2276 IRVKRVSTFSGRSPPAPPPYKAPRLDEDGEASEDTPQVP 2314
Score = 37.4 bits (85), Expect = 0.12
Identities = 39/150 (26%), Positives = 55/150 (36%), Gaps = 28/150 (18%)
Query: 1452 KRRGRPRKQPTQFDEDSRDQMPVLEKCIDLPSKR---GQKPSLSPLVLEPAAS-----QD 1503
++RGRP P+Q E + P+ G P SP V + + +
Sbjct: 467 RKRGRPPLTPSQRAEREAARAGPEGTSPPTPTPSTATGGPPEDSPTVAPKSTTFLKNIRQ 526
Query: 1504 TIMATIEA----VIHMAREAPPLPPPPPPPLPPPPP--PPLPPPPPLPKTPRGGKRKHKP 1557
IM + A VI R PP PP + P PP+ PP+P+ P
Sbjct: 527 FIMPVVSARSSRVIKTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPA-------- 578
Query: 1558 QAPAQPPQQSPPQQPLPQEEEVKAKRQRKS 1587
P SPP+ P P V +R+S
Sbjct: 579 ------PVPSPPRAPTPPSTPVPLPEKRRS 602
Score = 35.0 bits (79), Expect = 0.58
Identities = 20/82 (24%), Positives = 33/82 (40%), Gaps = 2/82 (2%)
Query: 1460 QPTQFDEDSRDQMPVLEKCIDLPSKRGQKPSLSPLVLEPAASQDTIMATIEAVIHMAREA 1519
+P + +P + P K P +P + +Q ++ ++A+ +
Sbjct: 692 EPRAVGRTNHLSLPRFAPVVTTPVKAEVSPHGAPALSNGPQTQAQLLQPLQAL--QTQLL 749
Query: 1520 PPLPPPPPPPLPPPPPPPLPPP 1541
P PPP P L PPP P PP
Sbjct: 750 PQALPPPQPQLQPPPSPQQMPP 771
Score = 35.0 bits (79), Expect = 0.58
Identities = 30/112 (26%), Positives = 39/112 (34%), Gaps = 20/112 (17%)
Query: 1482 PSKRGQKPSLSPLVLEPAASQDTIMATIEAVIHMAREAPPLPPPPPPPLPPPPPPPLPPP 1541
P+ KP+ S ++L Q + MA E P+PPP PP PP P
Sbjct: 2179 PAPEPPKPATSKIILVNKLGQ--------VFVKMAGEGEPVPPPVKQ--PPLPPTISPTA 2228
Query: 1542 PPLPKTPRGGKRKHKPQAPAQPPQQSPPQQPL----------PQEEEVKAKR 1583
P P G P P PP PL P + ++ KR
Sbjct: 2229 PTSWTLPPGPLLGVLPVVGVVRPAPPPPPPPLTLVLSSGPASPPRQAIRVKR 2280
Score = 32.7 bits (73), Expect = 2.9
Identities = 21/59 (35%), Positives = 25/59 (42%), Gaps = 8/59 (13%)
Query: 1516 AREAPPLPPPPPPPLPPPPP----PPLPPPPP----LPKTPRGGKRKHKPQAPAQPPQQ 1566
+R PL P PPP PP P L PPP TP G+ AP+ PP +
Sbjct: 1913 SRRPSPLAPRPPPSRWASPPLKTSPQLRVPPPTSVVTALTPTSGELAPPGPAPSPPPPE 1971
Score = 31.2 bits (69), Expect = 8.4
Identities = 39/180 (21%), Positives = 63/180 (35%), Gaps = 17/180 (9%)
Query: 736 PPPSEEPKTAIKHPRPVSSQPDVPAVPSNFQSLVASSPAAMHPLSTQLGGSNGNLSPAST 795
P PS +++ H P PD PA P + SP A P ++ SP
Sbjct: 1884 PLPSPGSPSSLTHHIPTVGDPDFPAPPRRSR---RPSPLAPRPPPSRWASPPLKTSP--- 1937
Query: 796 ETNFSELKTMPNLQPISAL-PTKTQKGIHSGTWKLSPPRLMANSPSHLCEIGSLK----E 850
+L+ P ++AL PT + PP + + + L +
Sbjct: 1938 -----QLRVPPPTSVVTALTPTSGELAPPGPAPSPPPPEDLGPDFEDMEVVSGLSAADLD 1992
Query: 851 ITLSPVSESHSEETIPSDSGIGTDNNSTSDQAEKSSESRRRY-SFDFCSLDNPEAIPSDT 909
S + +E I + +G+ + D +E+ S RY F + P PS T
Sbjct: 1993 FAASLLGTEPFQEEIVAAGAMGSSHGGPGDSSEEESSPTSRYIHFPVTVVSAPGLAPSAT 2052
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 60.1 bits (144), Expect = 2e-08
Identities = 26/50 (52%), Positives = 29/50 (58%)
Query: 1520 PPLPPPPPPPLPPPPPPPLPPPPPLPKTPRGGKRKHKPQAPAQPPQQSPP 1569
PP PPPPPPP PPPPPPP PPP P P +P+ K A P + P
Sbjct: 2405 PPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATP 2454
Score = 58.5 bits (140), Expect = 5e-08
Identities = 32/74 (43%), Positives = 35/74 (47%)
Query: 1487 QKPSLSPLVLEPAASQDTIMATIEAVIHMAREAPPLPPPPPPPLPPPPPPPLPPPPPLPK 1546
Q PS SP V A + I PP PPPPPPP PPPPPPP PPP PK
Sbjct: 2375 QLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPK 2434
Query: 1547 TPRGGKRKHKPQAP 1560
K+K +P
Sbjct: 2435 PTILPKKKLTVASP 2448
Score = 54.7 bits (130), Expect = 7e-07
Identities = 25/52 (48%), Positives = 25/52 (48%), Gaps = 22/52 (42%)
Query: 1523 PPPPPPPLPPPPPPPLPPPPPLPKTPRGGKRKHKPQAPAQPPQQSPPQQPLP 1574
PPPPPPP PPPPPPP PPPPPLP PP P P
Sbjct: 2406 PPPPPPPPPPPPPPPPPPPPPLP----------------------PPTSPKP 2435
Score = 44.3 bits (103), Expect = 0.001
Identities = 24/63 (38%), Positives = 31/63 (49%), Gaps = 2/63 (3%)
Query: 1516 AREAPPLPPPPPPPLPPPPPPPLP-PPPPLPKTPRGGK-RKHKPQAPAQPPQQSPPQQPL 1573
A++ P PP P P PPP P P P P+ P K +P + PPQQ P +P
Sbjct: 461 AQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPS 520
Query: 1574 PQE 1576
PQ+
Sbjct: 521 PQQ 523
Score = 43.9 bits (102), Expect = 0.001
Identities = 109/474 (22%), Positives = 163/474 (34%), Gaps = 83/474 (17%)
Query: 423 SIKAVVEKIMP------EKALASGITMSSEVVNRILSNSEGNKKDPRVPKLSKMI-ENES 475
++ +VV K P +A T +VV + EG K P + K I + +
Sbjct: 165 AVSSVVNKFNPFDLISDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQG 224
Query: 476 PSVG-LETGGNAEKVIPGGVSKPRKPPMVMTPPTCTDHSPSRKLPEIQHPKFAAKRRWTC 534
P L+ G + + K + P P T + P+ H K +R
Sbjct: 225 PGRDPLQQDGTPKSISSQQPEKIKSQP----PGTGKPIQGPTQTPQTDHAKLPLQR---- 276
Query: 535 SKPKPSTMLREAVMATSDKLMLEPPSAYPITPSSPLYTNTDSLTVITPVKKKRGRPKKQP 594
+P T + V S K L PS PI +P P ++ G K QP
Sbjct: 277 DASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPG----------KPPAQQPGHEKSQP 326
Query: 595 -----------LLTVETIHEGTSTSPVSPISREFPGTKKRKRRR-NLAKLAQLVPGEDKP 642
L GT PV P PGT K + AK G +KP
Sbjct: 327 GPAKPPAQPSGLTKPLAQQPGTVKPPVQP-----PGTTKPPAQPLGPAKPPAQQTGSEKP 381
Query: 643 MSEMKFHKKVGKLGVLDKKTIKTINKMKTLKRKNILNQILSCSSSVALKAKAP-----PE 697
SE K + + + K + K ++ + L+ + AKAP P
Sbjct: 382 SSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPV 441
Query: 698 TSPGAAAIESKLGKQINVSKRGTIYIGKKRGRKPRAELPPPSEEPKTAIKHPRPVSSQPD 757
PG I ++ Q K G KP ++LP P++ P +P QP
Sbjct: 442 QQPGPGKIPAQ---QAGPGKTSAQQTGPT---KPPSQLPGPAKPPPQQPGPAKPPPQQPG 495
Query: 758 VPAVPSNFQSLVASSPAAMHPLSTQLGGSNGN-LSPASTETNFSELKTMPNLQPISALPT 816
PS P + P Q G + + P ST+ P+ QP SA P+
Sbjct: 496 SAKPPS-------QQPGSTKPPPQQPGPAKPSPQQPGSTKP--------PSQQPGSAKPS 540
Query: 817 KTQKGIHSGTWKLSPPRLMA-NSPSHLCEIGSLKEI---TLSPVSESHSEETIP 866
Q SP + A S + + GS K + T+SP ++ + +P
Sbjct: 541 AQQP---------SPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLP 585
Score = 43.9 bits (102), Expect = 0.001
Identities = 126/651 (19%), Positives = 224/651 (34%), Gaps = 104/651 (15%)
Query: 240 ESGRETASTSKIPALEPVASFAKAQGKKGSAGNTWSQLSNNNKD-LLLGGVAPSPSSHSS 298
+S + +K P +P AQ + G T +Q + K L G A P
Sbjct: 428 QSPAKAPGPTKTPVQQPGPGKIPAQ--QAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPG 485
Query: 299 PAPPSSSAECNGLQPLVDQDGGGTKEPPEPPTVGSKKKSSKKDVISQTIPNPDLDWVKNA 358
PA P + P Q G TK PP+ P G K P+P
Sbjct: 486 PAKPPPQQPGSAKPP--SQQPGSTKPPPQQP--GPAK------------PSPQ------- 522
Query: 359 QKAFDNTEGKREGYSADSAQEASPARQNVSSASNPENDSSHVRITIPIKAPSLDPTNHKR 418
Q ++ G + SAQ+ SPA+ + ++ P + + + P++ P++ P + K+
Sbjct: 523 QPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGK---PLQPPTVSP-SAKQ 578
Query: 419 KKRQSIKAVVEKI---------MPEKALASGITMSSEVVNRILSNSEGNKKDPRVPKLSK 469
Q + + + +PEKA + T V + G +P + ++ +
Sbjct: 579 PPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLC----GFNPNPHLTEVKE 634
Query: 470 MIENESPSVGLETGGNAEKVIPGGVSKPRKP-PMVMTPPTCTDHSPSRKLPEIQH--PKF 526
+ + + GG+ V P P P + T P T + S+ P+ Q PK
Sbjct: 635 WL-CLNCQMKRALGGDLAPV-------PSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKK 686
Query: 527 AAKRRWTCSK----PKPSTMLREAVMATSDKLML-EPPSAYPIT-PSSPLYTNTDSLTVI 580
A + SK KP ++++ + S +PP A ++ P+ P + S
Sbjct: 687 DAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDK 746
Query: 581 TPVKKKRGRPKKQPLLTVETIHEGTSTS----PVSPISREFPGTKKRKRRRNLAKLAQLV 636
PV + + K T + + ++T+ P S + + + + AK +Q
Sbjct: 747 APVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSF 806
Query: 637 PGEDKPMSEMKFHKKVGKLGVLDKKTIKTINKMKTLKRKNILNQILSCSSSVALKAKAPP 696
P P E K+ D K I S S + P
Sbjct: 807 P----PTGE--------KVSPFDSKAIPR-----------------PASDSKIISHPGPS 837
Query: 697 ETSPGAAAIESKLGKQINVSKRGTIYIGKKRGRKPRAELPPPSEEPKTAIKHPRPVSSQP 756
S G ++ K+ K+ + K KP + P P+ P Q
Sbjct: 838 SESKGQKQVDPVQKKE--EPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQS 895
Query: 757 DVPAVPSNFQSL----VASSPAA-----MHPLSTQLGGSNGNLSPASTETNFSELKTMPN 807
P S SL + +P + ++ +L G ++ ++ + + P+
Sbjct: 896 PKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPH 955
Query: 808 LQPISALPTKTQKGIHSGTWKLSPPRLMANSPSHLCEIGSLKEITLSPVSE 858
Q P K PP+ +P + +K+ T +P +E
Sbjct: 956 SQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAE 1006
Score = 40.8 bits (94), Expect = 0.011
Identities = 24/65 (36%), Positives = 29/65 (44%), Gaps = 3/65 (4%)
Query: 1521 PLPPPPPPPLP-PPPPPPLPPPPPLPKTPRGGKRKHKPQ--APAQPPQQSPPQQPLPQEE 1577
P P PPP P P PPP P P + + G K PQ PA+P Q P P ++
Sbjct: 474 PGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQ 533
Query: 1578 EVKAK 1582
AK
Sbjct: 534 PGSAK 538
Score = 40.8 bits (94), Expect = 0.011
Identities = 20/48 (41%), Positives = 20/48 (41%), Gaps = 24/48 (50%)
Query: 1527 PPPLPPPPPPPLPPPPPLPKTPRGGKRKHKPQAPAQPPQQSPPQQPLP 1574
PPP PPPPPPP PPPPP PP PLP
Sbjct: 2405 PPPPPPPPPPPPPPPPP------------------------PPPPPLP 2428
Score = 39.3 bits (90), Expect = 0.031
Identities = 45/169 (26%), Positives = 61/169 (36%), Gaps = 32/169 (18%)
Query: 1428 DHVNKILKAKRLQRQSKTGN----NFVKKRRGRPRKQPTQFDEDSRD--QMPVLEKCIDL 1481
DH L+ + Q+K + VK P K P Q + Q P EK
Sbjct: 268 DHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPG 327
Query: 1482 PSKRGQKPS--LSPLVLEPAASQDTIMATIEAVIHMAREAPPLPPPPPPPLPPPPPPPL- 1538
P+K +PS PL +P + + + P PP PL P PP
Sbjct: 328 PAKPPAQPSGLTKPLAQQPGTVKPPV------------QPPGTTKPPAQPLGPAKPPAQQ 375
Query: 1539 ----------PPPPPLPKTPRGGKRKHKPQAPAQPP-QQSPPQQPLPQE 1576
P P L + P GK + PA+PP QQ +PL Q+
Sbjct: 376 TGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQ 424
Score = 37.7 bits (86), Expect = 0.090
Identities = 33/115 (28%), Positives = 45/115 (39%), Gaps = 6/115 (5%)
Query: 1479 IDLPSKRGQKPSLSPLVLEPAASQDTIMATIEAVIHMAREAPPLPPPPPPPLPPPPPPPL 1538
+ P Q+P L P ++ + I A++A P P PP L
Sbjct: 415 VGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIP-AQQAGPGKTSAQQTGPTKPPSQL 473
Query: 1539 P-PPPPLPKTPRGGKRKHKPQAP--AQPPQQSPPQQPLPQEEEVKAKRQRKSRGS 1590
P P P P+ P G K PQ P A+PP Q P P ++ AK + GS
Sbjct: 474 PGPAKPPPQQP--GPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGS 526
Score = 37.4 bits (85), Expect = 0.12
Identities = 40/144 (27%), Positives = 57/144 (39%), Gaps = 19/144 (13%)
Query: 1455 GRPRKQPTQFDEDSRDQMPVLE-------KCIDLPSKRGQKPSLSPLVLEPAASQDTI-M 1506
G+P + PTQ + ++P+ K D+ KPSL P +P Q T
Sbjct: 255 GKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSL-PSPSKPPIQQPTPGK 313
Query: 1507 ATIEAVIHMAREAPPLPPPPPP-----PLPPPPPPPLPPPPPLPKTPRGGKRKHKPQAPA 1561
+ H + P PP P PL P PP P P K +P PA
Sbjct: 314 PPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQP----PGTTKPPAQPLGPA 369
Query: 1562 QPP-QQSPPQQPLPQEEEVKAKRQ 1584
+PP QQ+ ++P ++ KA Q
Sbjct: 370 KPPAQQTGSEKPSSEQPGPKALAQ 393
Score = 37.4 bits (85), Expect = 0.12
Identities = 58/290 (20%), Positives = 120/290 (41%), Gaps = 29/290 (10%)
Query: 1179 TGFSSHILSERLSSADKELPLVSEKNKHKEKQKHQHSEAGHKASKNNFEVDTLSTLSLSD 1238
TG+SS +S L +P EK+ K +K S+ +S ++ + LS+ +
Sbjct: 1363 TGYSSDGISSSLGEIPSLIP-TDEKDILKGLKKDSFSQESSPSSPSDLAKLESTVLSILE 1421
Query: 1239 AQHWTQAKEKGDLSSEPVDSCTKRYSGSGGDGGSTRSENLDVFSEMNPSNDKWDSDVSGS 1298
AQ T A EK + ++P + ++ + + SE L++ + ++ S
Sbjct: 1422 AQASTLADEKSEKKTQPHEVSPEQPKDQ--EKTQSLSETLEITIS--------EEEIKES 1471
Query: 1299 KRRSYEGFGTYREKDIQAFKMNRKERSSYDSSMSPGMPSPHLKVDQTAVHSKNEGSVPTM 1358
+ + F ++DI + K + KE+S + ++ P+ V+++ S++E S +
Sbjct: 1472 QEERKDTFKKDSQQDIPSSK-DHKEKSEFVDDITT-RREPYDSVEES---SESENS--PV 1524
Query: 1359 MTRKKPAAVDSVTIPPAPVLSLLAASAATSDAVGSSLKKRFKRREIEAIQCEVRKMCNYT 1418
RK+ +V S + + D+ GS ++ F R++I + +
Sbjct: 1525 PQRKRRTSVGSSS----------SDEYKQEDSQGSGEEEDFIRKQIIEMSAD-EDASGSE 1573
Query: 1419 KILSTKKNLDHVNKILKAKRLQRQSKTGNNFVKKRRGRPRKQPTQFDEDS 1468
+ L ++ ++++ + G K R RK T DED+
Sbjct: 1574 DDEFIRNQLKEISSSTESQKKEETKGKGKITAGKHRRLTRKSSTSIDEDA 1623
Score = 36.2 bits (82), Expect = 0.26
Identities = 35/123 (28%), Positives = 49/123 (39%), Gaps = 12/123 (9%)
Query: 1455 GRPRKQPTQFDEDSRDQMPVLEKCIDLPSKRGQKPSLSPLVLEPAASQDTIMATIEAVIH 1514
G P+ +Q E + Q P K I P++ Q + A+ T A I +
Sbjct: 234 GTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADI---VR 290
Query: 1515 MAREAPPLPPPPPPPLPPPPPPPLPPPPPLPKTPRGGKRKHKPQAPAQPP-QQSPPQQPL 1573
P LP P PP+ P P P + G K +P PA+PP Q S +PL
Sbjct: 291 GESVKPSLPSPSKPPI-------QQPTPGKPPAQQPGHEKSQP-GPAKPPAQPSGLTKPL 342
Query: 1574 PQE 1576
Q+
Sbjct: 343 AQQ 345
Score = 36.2 bits (82), Expect = 0.26
Identities = 126/638 (19%), Positives = 220/638 (34%), Gaps = 67/638 (10%)
Query: 297 SSPAPPSSSAECNGLQPLVDQDGGGTKEPPEPPTVGSKKKSSKKDVISQTIPNPDLDWVK 356
S P P A+ +GL + Q G K P +PP G+ K ++ ++
Sbjct: 324 SQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPP--GTTKPPAQPLGPAKPPAQQTGSEKP 381
Query: 357 NAQKAFDNTEGKREGYSADSAQEASPARQNVSSASNPENDSSHVRITIPIKAPSLDPTNH 416
++++ + G AQ+ PA+ P+ + + P KAP PT
Sbjct: 382 SSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPG--PTKT 439
Query: 417 KRKKRQSIKAVVEKIMPEKALASGITMSSEVVNRILSNSEGNKKDPRVPKLSKMIENESP 476
++ K ++ P K A T ++ +++ + K P+ P +K
Sbjct: 440 PVQQPGPGKIPAQQAGPGKTSAQQ-TGPTKPPSQLPGPA---KPPPQQPGPAKPPPQ--- 492
Query: 477 SVGLETGGNAEKVIPGGVSKPRKPPMVMTPPTCTDHSPSRKLPEIQHPKFAAKRRWTCSK 536
+ G G +KP PP P + P P Q P A S
Sbjct: 493 ----QPGSAKPPSQQPGSTKP--PPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSP 546
Query: 537 PKPST-MLREAVMATSDKLMLEPPSAYPITPSSPL---------YTNTDSLTVITPVKKK 586
KPS + V T L+PP+ P P NT L + P +K
Sbjct: 547 AKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVP-EKA 605
Query: 587 RGRPKKQPLLTVETIHEGTSTSPVSPISREFPGTKKRKRRRNLAKLAQLVPGEDKP---M 643
+ TV ++ G + +P +E+ + +R LA VP +P
Sbjct: 606 NFNTCTECQTTVCSLC-GFNPNPHLTEVKEWLCLNCQMKRALGGDLAP-VPSSPQPKLKT 663
Query: 644 SEMKFHKKVGKLGVLDKKTI--------KTINKMKTLKRKNILNQILSCSSSVALKAKAP 695
+ + V K ++T + ++K K+ L + + S + KAK P
Sbjct: 664 APVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQP 723
Query: 696 PETSPGAAAIESKLGKQINVSKRGTIYIGKKRGRKPRAELPPPSEEPKTAIKHPRPVSSQ 755
PE + K + + + K + P +P T + +++
Sbjct: 724 PEADSLSKPAPPKEPSVPSEQDKAPVADDKPK--------QPKMVKPTTDLVSSSSATTK 775
Query: 756 PDVPAVPSNFQSLVASSPAAMHPLSTQLGGSNGNLSPASTETNFSELKTMPNLQPISALP 815
PD+P+ Q+ ++P PL T + + P + + + K +P P
Sbjct: 776 PDIPSSKVQSQAEEKTTP----PLKTDSAKPSQSFPPTGEKVSPFDSKAIPR-------P 824
Query: 816 TKTQKGI-HSGTWKLSPPRLMANSPSHLCEIGSLKEITLSPVSES----HSEETIPSDSG 870
K I H G S + + P E + +SP ++ T P
Sbjct: 825 ASDSKIISHPGPSSESKGQKQVD-PVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRP 883
Query: 871 IGTDNNSTSDQAEKSSESRRRYSFDFCSL-DNPEAIPS 907
T Q+ K E RR+S + S+ D P++ P+
Sbjct: 884 TAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPT 921
Score = 36.2 bits (82), Expect = 0.26
Identities = 24/68 (35%), Positives = 28/68 (41%), Gaps = 11/68 (16%)
Query: 1520 PPLPPPPPPPLPPPP--------PPPLPPPPPLPKTPRGGKRKHKPQAP--AQPPQQSP- 1568
P PPP P PP PPP P P P + G K Q P A+P Q P
Sbjct: 486 PAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPS 545
Query: 1569 PQQPLPQE 1576
P +P Q+
Sbjct: 546 PAKPSAQQ 553
Score = 35.4 bits (80), Expect = 0.44
Identities = 26/88 (29%), Positives = 33/88 (37%), Gaps = 12/88 (13%)
Query: 1520 PPLPPPPPPPLPPPP----PPPLPPPPPLPKTPRGGKRKHKPQAP--AQPPQQSP----- 1568
PP P P P P P PP P P + G K PQ P +PP Q P
Sbjct: 480 PPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKP 539
Query: 1569 -PQQPLPQEEEVKAKRQRKSRGSESEVL 1595
QQP P + + + S+ + L
Sbjct: 540 SAQQPSPAKPSAQQSTKPVSQTGSGKPL 567
Score = 34.7 bits (78), Expect = 0.76
Identities = 29/116 (25%), Positives = 42/116 (36%), Gaps = 17/116 (14%)
Query: 1478 CIDLPSKRGQKPSLSPLVLEPAASQDTIMATIEAVIHMAREAPPLPPP-----PPPPLPP 1532
C++ KR L+P+ P T T + + + P P P L
Sbjct: 637 CLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSK 696
Query: 1533 PPPPPLPPPPPLPKTPRGGKRKHKPQAPAQPPQQ-------SPPQQPLPQEEEVKA 1581
P P PPP T G P A A+ P + +PP++P E+ KA
Sbjct: 697 APEPKKPPPLVKQPTLHGS-----PSAKAKQPPEADSLSKPAPPKEPSVPSEQDKA 747
Score = 33.5 bits (75), Expect = 1.7
Identities = 123/624 (19%), Positives = 225/624 (36%), Gaps = 82/624 (13%)
Query: 16 ESDFLPVSSAKPPAAPGCAGEPLLSTPGPGKGIPVGGE--RMEPEEEDELGSGRDVDSNS 73
E D SS++ P +P + S+ G + GE + P +E ++ G DS S
Sbjct: 1342 EDDKSDTSSSQQPKSPQGLSDTGYSSDGISSSL---GEIPSLIPTDEKDILKGLKKDSFS 1398
Query: 74 NADSEKWVAGDG-LEEQEFSIKEAN---FTEGSLKLKIQTTKRAKKPPKNLENYICPPE- 128
S + LE SI EA + + K Q + + + PK+ E E
Sbjct: 1399 QESSPSSPSDLAKLESTVLSILEAQASTLADEKSEKKTQPHEVSPEQPKDQEKTQSLSET 1458
Query: 129 IKITI-----KQSGDQKVSRAGKNSKATKEEERSHSKKK-----LLTASDLAASDLKGFQ 178
++ITI K+S +++ K+S+ + H +K + T + S + +
Sbjct: 1459 LEITISEEEIKESQEERKDTFKKDSQQDIPSSKDHKEKSEFVDDITTRREPYDSVEESSE 1518
Query: 179 PQAYERPQKHSTLHYDTGLPQDFTGDTLKPKHQQKSSSQNHM-DWSTNSDSGPVTQNCFI 237
+ PQ+ + ++ + + +++ + + + S + D+ + FI
Sbjct: 1519 SENSPVPQRKRRTSVGSSSSDEYKQEDSQGSGEEEDFIRKQIIEMSADEDASGSEDDEFI 1578
Query: 238 SPESGRETASTSKIPALEPVASFAKAQGKKGSAGNTWSQLSNNNKDLLLGGVAPSPSSHS 297
+ ++ST E +GK +L+ + + S H
Sbjct: 1579 RNQLKEISSSTESQKKEE-------TKGKGKITAGKHRRLTRKSSTSIDEDAGRRHSWHD 1631
Query: 298 --------SPAPPSSSAECNGLQPLVDQDGGGT---KEPPEPPTVGSK--KKSSKKDVIS 344
SP + + LV GGG K T+ K +SS+K
Sbjct: 1632 EDDEAFDESPELKYRETKSQESEELVVTGGGGLRRFKTIELNSTIADKYSAESSQKKTSL 1691
Query: 345 QTIPNPDLDWVKNAQKAFDNTEGKREGYSADSAQEASPARQNVSSASNPENDSSHVRITI 404
P+L+ D + G EG S+ A +P S +S E+ S
Sbjct: 1692 YFDEEPELEMESLTDSPEDRSRG--EGSSSLHASSFTPGTSPTSVSSLDEDSDS------ 1743
Query: 405 PIKAPSLDPTNHKRKKRQSIKAVVEKIMPEKALASGITMSSEVVN-----RILSNSEGNK 459
P++ K + +Q KA + P L I SSE +L E +
Sbjct: 1744 -------SPSHKKGESKQQRKA---RHRPHGPLLPTIEDSSEEEELREEEELLKEQEKQR 1793
Query: 460 KDPRVPKLSKMIENESPSVGLETGGNAEKVIPGGVSKPRKPPMVMTPPTCTDHSPSRKLP 519
+ + + S +++ L E+ P+ PP ++P D SP+ +L
Sbjct: 1794 EIEQQQRKSSSKKSKKDKDELRAQRRRER--------PKTPPSNLSP--IEDASPTEELR 1843
Query: 520 EIQHPKFAAKRRWTCSKPKPSTMLREAVMATSDKLMLEPPSAYPITPSSPLYTNTDSLTV 579
Q + R +CS+ PS S + ++E Y + + LY+ TD ++
Sbjct: 1844 --QAAEMEELHRSSCSEYSPSIESDPEGFEISPEKIIEVQKVYKLPTAVSLYSPTDEQSI 1901
Query: 580 ITPVKKKRGRPKKQPLLTVETIHE 603
+ +K G K L + E ++E
Sbjct: 1902 M----QKEGSQK--ALKSAEEMYE 1919
Score = 32.3 bits (72), Expect = 3.8
Identities = 21/81 (25%), Positives = 29/81 (35%), Gaps = 4/81 (4%)
Query: 1520 PPLPPPPPPPLPPPP----PPPLPPPPPLPKTPRGGKRKHKPQAPAQPPQQSPPQQPLPQ 1575
PP P P P P P PP P P + K Q +P Q+ +PL
Sbjct: 510 PPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQP 569
Query: 1576 EEEVKAKRQRKSRGSESEVLP 1596
+ +Q S+G + P
Sbjct: 570 PTVSPSAKQPPSQGLPKTICP 590
Score = 31.2 bits (69), Expect = 8.4
Identities = 34/136 (25%), Positives = 48/136 (35%), Gaps = 17/136 (12%)
Query: 1462 TQFDEDSRDQMPVLEKCIDLPSKRGQKP-SLSPLVLEPAASQDTI-MATIEAVIHMAREA 1519
T + S+ P EK SK +P S S ++ P S ++ ++ V +E
Sbjct: 797 TDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPV--QKKEE 854
Query: 1520 PPLPPPPPPPLPPPPPPPLPPPPPLPKTPRGGKRKHKPQAPAQPPQQS------------ 1567
P P P P P P P P G+ PQ +P +QS
Sbjct: 855 PKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITD 914
Query: 1568 -PPQQPLPQEEEVKAK 1582
P QP +E V K
Sbjct: 915 APKSQPTTPQETVTGK 930
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 60.1 bits (144), Expect = 2e-08
Identities = 26/50 (52%), Positives = 29/50 (58%)
Query: 1520 PPLPPPPPPPLPPPPPPPLPPPPPLPKTPRGGKRKHKPQAPAQPPQQSPP 1569
PP PPPPPPP PPPPPPP PPP P P +P+ K A P + P
Sbjct: 2405 PPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATP 2454
Score = 58.5 bits (140), Expect = 5e-08
Identities = 32/74 (43%), Positives = 35/74 (47%)
Query: 1487 QKPSLSPLVLEPAASQDTIMATIEAVIHMAREAPPLPPPPPPPLPPPPPPPLPPPPPLPK 1546
Q PS SP V A + I PP PPPPPPP PPPPPPP PPP PK
Sbjct: 2375 QLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPK 2434
Query: 1547 TPRGGKRKHKPQAP 1560
K+K +P
Sbjct: 2435 PTILPKKKLTVASP 2448
Score = 54.7 bits (130), Expect = 7e-07
Identities = 25/52 (48%), Positives = 25/52 (48%), Gaps = 22/52 (42%)
Query: 1523 PPPPPPPLPPPPPPPLPPPPPLPKTPRGGKRKHKPQAPAQPPQQSPPQQPLP 1574
PPPPPPP PPPPPPP PPPPPLP PP P P
Sbjct: 2406 PPPPPPPPPPPPPPPPPPPPPLP----------------------PPTSPKP 2435
Score = 44.3 bits (103), Expect = 0.001
Identities = 24/63 (38%), Positives = 31/63 (49%), Gaps = 2/63 (3%)
Query: 1516 AREAPPLPPPPPPPLPPPPPPPLP-PPPPLPKTPRGGK-RKHKPQAPAQPPQQSPPQQPL 1573
A++ P PP P P PPP P P P P+ P K +P + PPQQ P +P
Sbjct: 461 AQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPS 520
Query: 1574 PQE 1576
PQ+
Sbjct: 521 PQQ 523
Score = 43.9 bits (102), Expect = 0.001
Identities = 109/474 (22%), Positives = 163/474 (34%), Gaps = 83/474 (17%)
Query: 423 SIKAVVEKIMP------EKALASGITMSSEVVNRILSNSEGNKKDPRVPKLSKMI-ENES 475
++ +VV K P +A T +VV + EG K P + K I + +
Sbjct: 165 AVSSVVNKFNPFDLISDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQG 224
Query: 476 PSVG-LETGGNAEKVIPGGVSKPRKPPMVMTPPTCTDHSPSRKLPEIQHPKFAAKRRWTC 534
P L+ G + + K + P P T + P+ H K +R
Sbjct: 225 PGRDPLQQDGTPKSISSQQPEKIKSQP----PGTGKPIQGPTQTPQTDHAKLPLQR---- 276
Query: 535 SKPKPSTMLREAVMATSDKLMLEPPSAYPITPSSPLYTNTDSLTVITPVKKKRGRPKKQP 594
+P T + V S K L PS PI +P P ++ G K QP
Sbjct: 277 DASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPG----------KPPAQQPGHEKSQP 326
Query: 595 -----------LLTVETIHEGTSTSPVSPISREFPGTKKRKRRR-NLAKLAQLVPGEDKP 642
L GT PV P PGT K + AK G +KP
Sbjct: 327 GPAKPPAQPSGLTKPLAQQPGTVKPPVQP-----PGTTKPPAQPLGPAKPPAQQTGSEKP 381
Query: 643 MSEMKFHKKVGKLGVLDKKTIKTINKMKTLKRKNILNQILSCSSSVALKAKAP-----PE 697
SE K + + + K + K ++ + L+ + AKAP P
Sbjct: 382 SSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPV 441
Query: 698 TSPGAAAIESKLGKQINVSKRGTIYIGKKRGRKPRAELPPPSEEPKTAIKHPRPVSSQPD 757
PG I ++ Q K G KP ++LP P++ P +P QP
Sbjct: 442 QQPGPGKIPAQ---QAGPGKTSAQQTGPT---KPPSQLPGPAKPPPQQPGPAKPPPQQPG 495
Query: 758 VPAVPSNFQSLVASSPAAMHPLSTQLGGSNGN-LSPASTETNFSELKTMPNLQPISALPT 816
PS P + P Q G + + P ST+ P+ QP SA P+
Sbjct: 496 SAKPPS-------QQPGSTKPPPQQPGPAKPSPQQPGSTKP--------PSQQPGSAKPS 540
Query: 817 KTQKGIHSGTWKLSPPRLMA-NSPSHLCEIGSLKEI---TLSPVSESHSEETIP 866
Q SP + A S + + GS K + T+SP ++ + +P
Sbjct: 541 AQQP---------SPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLP 585
Score = 43.9 bits (102), Expect = 0.001
Identities = 126/651 (19%), Positives = 224/651 (34%), Gaps = 104/651 (15%)
Query: 240 ESGRETASTSKIPALEPVASFAKAQGKKGSAGNTWSQLSNNNKD-LLLGGVAPSPSSHSS 298
+S + +K P +P AQ + G T +Q + K L G A P
Sbjct: 428 QSPAKAPGPTKTPVQQPGPGKIPAQ--QAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPG 485
Query: 299 PAPPSSSAECNGLQPLVDQDGGGTKEPPEPPTVGSKKKSSKKDVISQTIPNPDLDWVKNA 358
PA P + P Q G TK PP+ P G K P+P
Sbjct: 486 PAKPPPQQPGSAKPP--SQQPGSTKPPPQQP--GPAK------------PSPQ------- 522
Query: 359 QKAFDNTEGKREGYSADSAQEASPARQNVSSASNPENDSSHVRITIPIKAPSLDPTNHKR 418
Q ++ G + SAQ+ SPA+ + ++ P + + + P++ P++ P + K+
Sbjct: 523 QPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGK---PLQPPTVSP-SAKQ 578
Query: 419 KKRQSIKAVVEKI---------MPEKALASGITMSSEVVNRILSNSEGNKKDPRVPKLSK 469
Q + + + +PEKA + T V + G +P + ++ +
Sbjct: 579 PPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLC----GFNPNPHLTEVKE 634
Query: 470 MIENESPSVGLETGGNAEKVIPGGVSKPRKP-PMVMTPPTCTDHSPSRKLPEIQH--PKF 526
+ + + GG+ V P P P + T P T + S+ P+ Q PK
Sbjct: 635 WL-CLNCQMKRALGGDLAPV-------PSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKK 686
Query: 527 AAKRRWTCSK----PKPSTMLREAVMATSDKLML-EPPSAYPIT-PSSPLYTNTDSLTVI 580
A + SK KP ++++ + S +PP A ++ P+ P + S
Sbjct: 687 DAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDK 746
Query: 581 TPVKKKRGRPKKQPLLTVETIHEGTSTS----PVSPISREFPGTKKRKRRRNLAKLAQLV 636
PV + + K T + + ++T+ P S + + + + AK +Q
Sbjct: 747 APVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSF 806
Query: 637 PGEDKPMSEMKFHKKVGKLGVLDKKTIKTINKMKTLKRKNILNQILSCSSSVALKAKAPP 696
P P E K+ D K I S S + P
Sbjct: 807 P----PTGE--------KVSPFDSKAIPR-----------------PASDSKIISHPGPS 837
Query: 697 ETSPGAAAIESKLGKQINVSKRGTIYIGKKRGRKPRAELPPPSEEPKTAIKHPRPVSSQP 756
S G ++ K+ K+ + K KP + P P+ P Q
Sbjct: 838 SESKGQKQVDPVQKKE--EPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQS 895
Query: 757 DVPAVPSNFQSL----VASSPAA-----MHPLSTQLGGSNGNLSPASTETNFSELKTMPN 807
P S SL + +P + ++ +L G ++ ++ + + P+
Sbjct: 896 PKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPH 955
Query: 808 LQPISALPTKTQKGIHSGTWKLSPPRLMANSPSHLCEIGSLKEITLSPVSE 858
Q P K PP+ +P + +K+ T +P +E
Sbjct: 956 SQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAE 1006
Score = 40.8 bits (94), Expect = 0.011
Identities = 24/65 (36%), Positives = 29/65 (44%), Gaps = 3/65 (4%)
Query: 1521 PLPPPPPPPLP-PPPPPPLPPPPPLPKTPRGGKRKHKPQ--APAQPPQQSPPQQPLPQEE 1577
P P PPP P P PPP P P + + G K PQ PA+P Q P P ++
Sbjct: 474 PGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQ 533
Query: 1578 EVKAK 1582
AK
Sbjct: 534 PGSAK 538
Score = 40.8 bits (94), Expect = 0.011
Identities = 20/48 (41%), Positives = 20/48 (41%), Gaps = 24/48 (50%)
Query: 1527 PPPLPPPPPPPLPPPPPLPKTPRGGKRKHKPQAPAQPPQQSPPQQPLP 1574
PPP PPPPPPP PPPPP PP PLP
Sbjct: 2405 PPPPPPPPPPPPPPPPP------------------------PPPPPLP 2428
Score = 39.3 bits (90), Expect = 0.031
Identities = 45/169 (26%), Positives = 61/169 (36%), Gaps = 32/169 (18%)
Query: 1428 DHVNKILKAKRLQRQSKTGN----NFVKKRRGRPRKQPTQFDEDSRD--QMPVLEKCIDL 1481
DH L+ + Q+K + VK P K P Q + Q P EK
Sbjct: 268 DHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPG 327
Query: 1482 PSKRGQKPS--LSPLVLEPAASQDTIMATIEAVIHMAREAPPLPPPPPPPLPPPPPPPL- 1538
P+K +PS PL +P + + + P PP PL P PP
Sbjct: 328 PAKPPAQPSGLTKPLAQQPGTVKPPV------------QPPGTTKPPAQPLGPAKPPAQQ 375
Query: 1539 ----------PPPPPLPKTPRGGKRKHKPQAPAQPP-QQSPPQQPLPQE 1576
P P L + P GK + PA+PP QQ +PL Q+
Sbjct: 376 TGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQ 424
Score = 37.7 bits (86), Expect = 0.090
Identities = 33/115 (28%), Positives = 45/115 (39%), Gaps = 6/115 (5%)
Query: 1479 IDLPSKRGQKPSLSPLVLEPAASQDTIMATIEAVIHMAREAPPLPPPPPPPLPPPPPPPL 1538
+ P Q+P L P ++ + I A++A P P PP L
Sbjct: 415 VGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIP-AQQAGPGKTSAQQTGPTKPPSQL 473
Query: 1539 P-PPPPLPKTPRGGKRKHKPQAP--AQPPQQSPPQQPLPQEEEVKAKRQRKSRGS 1590
P P P P+ P G K PQ P A+PP Q P P ++ AK + GS
Sbjct: 474 PGPAKPPPQQP--GPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGS 526
Score = 37.4 bits (85), Expect = 0.12
Identities = 40/144 (27%), Positives = 57/144 (39%), Gaps = 19/144 (13%)
Query: 1455 GRPRKQPTQFDEDSRDQMPVLE-------KCIDLPSKRGQKPSLSPLVLEPAASQDTI-M 1506
G+P + PTQ + ++P+ K D+ KPSL P +P Q T
Sbjct: 255 GKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSL-PSPSKPPIQQPTPGK 313
Query: 1507 ATIEAVIHMAREAPPLPPPPPP-----PLPPPPPPPLPPPPPLPKTPRGGKRKHKPQAPA 1561
+ H + P PP P PL P PP P P K +P PA
Sbjct: 314 PPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQP----PGTTKPPAQPLGPA 369
Query: 1562 QPP-QQSPPQQPLPQEEEVKAKRQ 1584
+PP QQ+ ++P ++ KA Q
Sbjct: 370 KPPAQQTGSEKPSSEQPGPKALAQ 393
Score = 37.4 bits (85), Expect = 0.12
Identities = 58/290 (20%), Positives = 120/290 (41%), Gaps = 29/290 (10%)
Query: 1179 TGFSSHILSERLSSADKELPLVSEKNKHKEKQKHQHSEAGHKASKNNFEVDTLSTLSLSD 1238
TG+SS +S L +P EK+ K +K S+ +S ++ + LS+ +
Sbjct: 1363 TGYSSDGISSSLGEIPSLIP-TDEKDILKGLKKDSFSQESSPSSPSDLAKLESTVLSILE 1421
Query: 1239 AQHWTQAKEKGDLSSEPVDSCTKRYSGSGGDGGSTRSENLDVFSEMNPSNDKWDSDVSGS 1298
AQ T A EK + ++P + ++ + + SE L++ + ++ S
Sbjct: 1422 AQASTLADEKSEKKTQPHEVSPEQPKDQ--EKTQSLSETLEITIS--------EEEIKES 1471
Query: 1299 KRRSYEGFGTYREKDIQAFKMNRKERSSYDSSMSPGMPSPHLKVDQTAVHSKNEGSVPTM 1358
+ + F ++DI + K + KE+S + ++ P+ V+++ S++E S +
Sbjct: 1472 QEERKDTFKKDSQQDIPSSK-DHKEKSEFVDDITT-RREPYDSVEES---SESENS--PV 1524
Query: 1359 MTRKKPAAVDSVTIPPAPVLSLLAASAATSDAVGSSLKKRFKRREIEAIQCEVRKMCNYT 1418
RK+ +V S + + D+ GS ++ F R++I + +
Sbjct: 1525 PQRKRRTSVGSSS----------SDEYKQEDSQGSGEEEDFIRKQIIEMSAD-EDASGSE 1573
Query: 1419 KILSTKKNLDHVNKILKAKRLQRQSKTGNNFVKKRRGRPRKQPTQFDEDS 1468
+ L ++ ++++ + G K R RK T DED+
Sbjct: 1574 DDEFIRNQLKEISSSTESQKKEETKGKGKITAGKHRRLTRKSSTSIDEDA 1623
Score = 36.2 bits (82), Expect = 0.26
Identities = 35/123 (28%), Positives = 49/123 (39%), Gaps = 12/123 (9%)
Query: 1455 GRPRKQPTQFDEDSRDQMPVLEKCIDLPSKRGQKPSLSPLVLEPAASQDTIMATIEAVIH 1514
G P+ +Q E + Q P K I P++ Q + A+ T A I +
Sbjct: 234 GTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADI---VR 290
Query: 1515 MAREAPPLPPPPPPPLPPPPPPPLPPPPPLPKTPRGGKRKHKPQAPAQPP-QQSPPQQPL 1573
P LP P PP+ P P P + G K +P PA+PP Q S +PL
Sbjct: 291 GESVKPSLPSPSKPPI-------QQPTPGKPPAQQPGHEKSQP-GPAKPPAQPSGLTKPL 342
Query: 1574 PQE 1576
Q+
Sbjct: 343 AQQ 345
Score = 36.2 bits (82), Expect = 0.26
Identities = 126/638 (19%), Positives = 220/638 (34%), Gaps = 67/638 (10%)
Query: 297 SSPAPPSSSAECNGLQPLVDQDGGGTKEPPEPPTVGSKKKSSKKDVISQTIPNPDLDWVK 356
S P P A+ +GL + Q G K P +PP G+ K ++ ++
Sbjct: 324 SQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPP--GTTKPPAQPLGPAKPPAQQTGSEKP 381
Query: 357 NAQKAFDNTEGKREGYSADSAQEASPARQNVSSASNPENDSSHVRITIPIKAPSLDPTNH 416
++++ + G AQ+ PA+ P+ + + P KAP PT
Sbjct: 382 SSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPG--PTKT 439
Query: 417 KRKKRQSIKAVVEKIMPEKALASGITMSSEVVNRILSNSEGNKKDPRVPKLSKMIENESP 476
++ K ++ P K A T ++ +++ + K P+ P +K
Sbjct: 440 PVQQPGPGKIPAQQAGPGKTSAQQ-TGPTKPPSQLPGPA---KPPPQQPGPAKPPPQ--- 492
Query: 477 SVGLETGGNAEKVIPGGVSKPRKPPMVMTPPTCTDHSPSRKLPEIQHPKFAAKRRWTCSK 536
+ G G +KP PP P + P P Q P A S
Sbjct: 493 ----QPGSAKPPSQQPGSTKP--PPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSP 546
Query: 537 PKPST-MLREAVMATSDKLMLEPPSAYPITPSSPL---------YTNTDSLTVITPVKKK 586
KPS + V T L+PP+ P P NT L + P +K
Sbjct: 547 AKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVP-EKA 605
Query: 587 RGRPKKQPLLTVETIHEGTSTSPVSPISREFPGTKKRKRRRNLAKLAQLVPGEDKP---M 643
+ TV ++ G + +P +E+ + +R LA VP +P
Sbjct: 606 NFNTCTECQTTVCSLC-GFNPNPHLTEVKEWLCLNCQMKRALGGDLAP-VPSSPQPKLKT 663
Query: 644 SEMKFHKKVGKLGVLDKKTI--------KTINKMKTLKRKNILNQILSCSSSVALKAKAP 695
+ + V K ++T + ++K K+ L + + S + KAK P
Sbjct: 664 APVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQP 723
Query: 696 PETSPGAAAIESKLGKQINVSKRGTIYIGKKRGRKPRAELPPPSEEPKTAIKHPRPVSSQ 755
PE + K + + + K + P +P T + +++
Sbjct: 724 PEADSLSKPAPPKEPSVPSEQDKAPVADDKPK--------QPKMVKPTTDLVSSSSATTK 775
Query: 756 PDVPAVPSNFQSLVASSPAAMHPLSTQLGGSNGNLSPASTETNFSELKTMPNLQPISALP 815
PD+P+ Q+ ++P PL T + + P + + + K +P P
Sbjct: 776 PDIPSSKVQSQAEEKTTP----PLKTDSAKPSQSFPPTGEKVSPFDSKAIPR-------P 824
Query: 816 TKTQKGI-HSGTWKLSPPRLMANSPSHLCEIGSLKEITLSPVSES----HSEETIPSDSG 870
K I H G S + + P E + +SP ++ T P
Sbjct: 825 ASDSKIISHPGPSSESKGQKQVD-PVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRP 883
Query: 871 IGTDNNSTSDQAEKSSESRRRYSFDFCSL-DNPEAIPS 907
T Q+ K E RR+S + S+ D P++ P+
Sbjct: 884 TAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPT 921
Score = 36.2 bits (82), Expect = 0.26
Identities = 24/68 (35%), Positives = 28/68 (41%), Gaps = 11/68 (16%)
Query: 1520 PPLPPPPPPPLPPPP--------PPPLPPPPPLPKTPRGGKRKHKPQAP--AQPPQQSP- 1568
P PPP P PP PPP P P P + G K Q P A+P Q P
Sbjct: 486 PAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPS 545
Query: 1569 PQQPLPQE 1576
P +P Q+
Sbjct: 546 PAKPSAQQ 553
Score = 35.4 bits (80), Expect = 0.44
Identities = 26/88 (29%), Positives = 33/88 (37%), Gaps = 12/88 (13%)
Query: 1520 PPLPPPPPPPLPPPP----PPPLPPPPPLPKTPRGGKRKHKPQAP--AQPPQQSP----- 1568
PP P P P P P PP P P + G K PQ P +PP Q P
Sbjct: 480 PPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKP 539
Query: 1569 -PQQPLPQEEEVKAKRQRKSRGSESEVL 1595
QQP P + + + S+ + L
Sbjct: 540 SAQQPSPAKPSAQQSTKPVSQTGSGKPL 567
Score = 34.7 bits (78), Expect = 0.76
Identities = 29/116 (25%), Positives = 42/116 (36%), Gaps = 17/116 (14%)
Query: 1478 CIDLPSKRGQKPSLSPLVLEPAASQDTIMATIEAVIHMAREAPPLPPP-----PPPPLPP 1532
C++ KR L+P+ P T T + + + P P P L
Sbjct: 637 CLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSK 696
Query: 1533 PPPPPLPPPPPLPKTPRGGKRKHKPQAPAQPPQQ-------SPPQQPLPQEEEVKA 1581
P P PPP T G P A A+ P + +PP++P E+ KA
Sbjct: 697 APEPKKPPPLVKQPTLHGS-----PSAKAKQPPEADSLSKPAPPKEPSVPSEQDKA 747
Score = 33.5 bits (75), Expect = 1.7
Identities = 123/624 (19%), Positives = 225/624 (36%), Gaps = 82/624 (13%)
Query: 16 ESDFLPVSSAKPPAAPGCAGEPLLSTPGPGKGIPVGGE--RMEPEEEDELGSGRDVDSNS 73
E D SS++ P +P + S+ G + GE + P +E ++ G DS S
Sbjct: 1342 EDDKSDTSSSQQPKSPQGLSDTGYSSDGISSSL---GEIPSLIPTDEKDILKGLKKDSFS 1398
Query: 74 NADSEKWVAGDG-LEEQEFSIKEAN---FTEGSLKLKIQTTKRAKKPPKNLENYICPPE- 128
S + LE SI EA + + K Q + + + PK+ E E
Sbjct: 1399 QESSPSSPSDLAKLESTVLSILEAQASTLADEKSEKKTQPHEVSPEQPKDQEKTQSLSET 1458
Query: 129 IKITI-----KQSGDQKVSRAGKNSKATKEEERSHSKKK-----LLTASDLAASDLKGFQ 178
++ITI K+S +++ K+S+ + H +K + T + S + +
Sbjct: 1459 LEITISEEEIKESQEERKDTFKKDSQQDIPSSKDHKEKSEFVDDITTRREPYDSVEESSE 1518
Query: 179 PQAYERPQKHSTLHYDTGLPQDFTGDTLKPKHQQKSSSQNHM-DWSTNSDSGPVTQNCFI 237
+ PQ+ + ++ + + +++ + + + S + D+ + FI
Sbjct: 1519 SENSPVPQRKRRTSVGSSSSDEYKQEDSQGSGEEEDFIRKQIIEMSADEDASGSEDDEFI 1578
Query: 238 SPESGRETASTSKIPALEPVASFAKAQGKKGSAGNTWSQLSNNNKDLLLGGVAPSPSSHS 297
+ ++ST E +GK +L+ + + S H
Sbjct: 1579 RNQLKEISSSTESQKKEE-------TKGKGKITAGKHRRLTRKSSTSIDEDAGRRHSWHD 1631
Query: 298 --------SPAPPSSSAECNGLQPLVDQDGGGT---KEPPEPPTVGSK--KKSSKKDVIS 344
SP + + LV GGG K T+ K +SS+K
Sbjct: 1632 EDDEAFDESPELKYRETKSQESEELVVTGGGGLRRFKTIELNSTIADKYSAESSQKKTSL 1691
Query: 345 QTIPNPDLDWVKNAQKAFDNTEGKREGYSADSAQEASPARQNVSSASNPENDSSHVRITI 404
P+L+ D + G EG S+ A +P S +S E+ S
Sbjct: 1692 YFDEEPELEMESLTDSPEDRSRG--EGSSSLHASSFTPGTSPTSVSSLDEDSDS------ 1743
Query: 405 PIKAPSLDPTNHKRKKRQSIKAVVEKIMPEKALASGITMSSEVVN-----RILSNSEGNK 459
P++ K + +Q KA + P L I SSE +L E +
Sbjct: 1744 -------SPSHKKGESKQQRKA---RHRPHGPLLPTIEDSSEEEELREEEELLKEQEKQR 1793
Query: 460 KDPRVPKLSKMIENESPSVGLETGGNAEKVIPGGVSKPRKPPMVMTPPTCTDHSPSRKLP 519
+ + + S +++ L E+ P+ PP ++P D SP+ +L
Sbjct: 1794 EIEQQQRKSSSKKSKKDKDELRAQRRRER--------PKTPPSNLSP--IEDASPTEELR 1843
Query: 520 EIQHPKFAAKRRWTCSKPKPSTMLREAVMATSDKLMLEPPSAYPITPSSPLYTNTDSLTV 579
Q + R +CS+ PS S + ++E Y + + LY+ TD ++
Sbjct: 1844 --QAAEMEELHRSSCSEYSPSIESDPEGFEISPEKIIEVQKVYKLPTAVSLYSPTDEQSI 1901
Query: 580 ITPVKKKRGRPKKQPLLTVETIHE 603
+ +K G K L + E ++E
Sbjct: 1902 M----QKEGSQK--ALKSAEEMYE 1919
Score = 32.3 bits (72), Expect = 3.8
Identities = 21/81 (25%), Positives = 29/81 (35%), Gaps = 4/81 (4%)
Query: 1520 PPLPPPPPPPLPPPP----PPPLPPPPPLPKTPRGGKRKHKPQAPAQPPQQSPPQQPLPQ 1575
PP P P P P P PP P P + K Q +P Q+ +PL
Sbjct: 510 PPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQP 569
Query: 1576 EEEVKAKRQRKSRGSESEVLP 1596
+ +Q S+G + P
Sbjct: 570 PTVSPSAKQPPSQGLPKTICP 590
Score = 31.2 bits (69), Expect = 8.4
Identities = 34/136 (25%), Positives = 48/136 (35%), Gaps = 17/136 (12%)
Query: 1462 TQFDEDSRDQMPVLEKCIDLPSKRGQKP-SLSPLVLEPAASQDTI-MATIEAVIHMAREA 1519
T + S+ P EK SK +P S S ++ P S ++ ++ V +E
Sbjct: 797 TDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPV--QKKEE 854
Query: 1520 PPLPPPPPPPLPPPPPPPLPPPPPLPKTPRGGKRKHKPQAPAQPPQQS------------ 1567
P P P P P P P P G+ PQ +P +QS
Sbjct: 855 PKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITD 914
Query: 1568 -PPQQPLPQEEEVKAK 1582
P QP +E V K
Sbjct: 915 APKSQPTTPQETVTGK 930
>gi|40807465 zinc finger protein 341 [Homo sapiens]
Length = 847
Score = 59.3 bits (142), Expect = 3e-08
Identities = 31/72 (43%), Positives = 34/72 (47%), Gaps = 14/72 (19%)
Query: 1479 IDLPSKRGQKPSLSPLVLEPAASQDTIMATIEAVIHMAREAPPLPPPPPPPLPPPPPPPL 1538
+D P +G P S L + S T PP PPPPPPPLPPPPPP
Sbjct: 151 LDQPMPQGPPPVQSSLNMHSVPSYLT--------------QPPPPPPPPPPLPPPPPPQP 196
Query: 1539 PPPPPLPKTPRG 1550
PPPPP P G
Sbjct: 197 PPPPPQSLGPPG 208
Score = 53.5 bits (127), Expect = 2e-06
Identities = 33/84 (39%), Positives = 39/84 (46%), Gaps = 18/84 (21%)
Query: 1501 SQDTIMATIEAVIHMAREAPPLPPPP---------PPPLPPPPPPPLPPPPPLPKTPRGG 1551
S D +M+ + A + + P PPP P L PPPPP PPPPPLP P
Sbjct: 137 SDDVLMSAMSAFTSLDQPMPQGPPPVQSSLNMHSVPSYLTQPPPPP-PPPPPLPPPP--- 192
Query: 1552 KRKHKPQAPAQPPQQ-SPPQQPLP 1574
PQ P PPQ PP +P P
Sbjct: 193 ----PPQPPPPPPQSLGPPGRPNP 212
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.127 0.365
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 76,173,786
Number of Sequences: 37866
Number of extensions: 4686180
Number of successful extensions: 91173
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1013
Number of HSP's successfully gapped in prelim test: 995
Number of HSP's that attempted gapping in prelim test: 33682
Number of HSP's gapped (non-prelim): 25069
length of query: 1596
length of database: 18,247,518
effective HSP length: 116
effective length of query: 1480
effective length of database: 13,855,062
effective search space: 20505491760
effective search space used: 20505491760
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.