Search of human proteins with 19424128

Search of human proteins with 19424128

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|19424128 alkaline ceramidase 1 [Homo sapiens]
         (264 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|19424128 alkaline ceramidase 1 [Homo sapiens]                      550   e-157
gi|71043498 alkaline ceramidase 2 [Homo sapiens]                      211   7e-55
gi|170932467 phytoceramidase, alkaline [Homo sapiens]                  64   1e-10
gi|45439335 porcupine isoform D [Homo sapiens]                         32   0.44 
gi|45439333 porcupine isoform C [Homo sapiens]                         32   0.44 
gi|45439331 porcupine isoform B [Homo sapiens]                         32   0.44 
gi|45439329 porcupine isoform A [Homo sapiens]                         32   0.44 
gi|110556646 transmembrane protein 8B isoform a [Homo sapiens]         30   2.2  
gi|110556642 transmembrane protein 8B isoform a [Homo sapiens]         30   2.2  
gi|148276981 transmembrane protein 184A [Homo sapiens]                 29   3.7  
gi|12965180 taste receptor, type 2, member 10 [Homo sapiens]           29   3.7  
gi|30039714 otopetrin 2 [Homo sapiens]                                 29   4.8  
gi|4885361 gastrin-releasing peptide receptor [Homo sapiens]           28   6.3  
gi|239757761 PREDICTED: similar to gastrin-releasing peptide rec...    28   6.3  
gi|21536357 TBP-associated factor 6 isoform delta [Homo sapiens]       28   6.3  
gi|21536355 TBP-associated factor 6 isoform gamma [Homo sapiens]       28   6.3  
gi|5032147 TBP-associated factor 6 isoform alpha [Homo sapiens]        28   6.3  
gi|21536359 TBP-associated factor 6 isoform alpha [Homo sapiens]       28   6.3  
gi|46409372 G protein-coupled receptor 153 [Homo sapiens]              28   8.2  

>gi|19424128 alkaline ceramidase 1 [Homo sapiens]
          Length = 264

 Score =  550 bits (1418), Expect = e-157
 Identities = 264/264 (100%), Positives = 264/264 (100%)

Query: 1   MPSIFAYQSSEVDWCESNFQYSELVAEFYNTFSNIPFFIFGPLMMLLMHPYAQKRSRYIY 60
           MPSIFAYQSSEVDWCESNFQYSELVAEFYNTFSNIPFFIFGPLMMLLMHPYAQKRSRYIY
Sbjct: 1   MPSIFAYQSSEVDWCESNFQYSELVAEFYNTFSNIPFFIFGPLMMLLMHPYAQKRSRYIY 60

Query: 61  VVWVLFMIIGLFSMYFHMTLSFLGQLLDEIAILWLLGSGYSIWMPRCYFPSFLGGNRSQF 120
           VVWVLFMIIGLFSMYFHMTLSFLGQLLDEIAILWLLGSGYSIWMPRCYFPSFLGGNRSQF
Sbjct: 61  VVWVLFMIIGLFSMYFHMTLSFLGQLLDEIAILWLLGSGYSIWMPRCYFPSFLGGNRSQF 120

Query: 121 IRLVFITTVVSTLLSFLRPTVNAYALNSIALHILYIVCQEYRKTSNKELRHLIEVSVVLW 180
           IRLVFITTVVSTLLSFLRPTVNAYALNSIALHILYIVCQEYRKTSNKELRHLIEVSVVLW
Sbjct: 121 IRLVFITTVVSTLLSFLRPTVNAYALNSIALHILYIVCQEYRKTSNKELRHLIEVSVVLW 180

Query: 181 AVALTSWISDRLLCSFWQRIHFFYLHSIWHVLISITFPYGMVTMALVDANYEMPGETLKV 240
           AVALTSWISDRLLCSFWQRIHFFYLHSIWHVLISITFPYGMVTMALVDANYEMPGETLKV
Sbjct: 181 AVALTSWISDRLLCSFWQRIHFFYLHSIWHVLISITFPYGMVTMALVDANYEMPGETLKV 240

Query: 241 RYWPRDSWPVGLPYVEIRGDDKDC 264
           RYWPRDSWPVGLPYVEIRGDDKDC
Sbjct: 241 RYWPRDSWPVGLPYVEIRGDDKDC 264


>gi|71043498 alkaline ceramidase 2 [Homo sapiens]
          Length = 275

 Score =  211 bits (536), Expect = 7e-55
 Identities = 98/250 (39%), Positives = 150/250 (60%), Gaps = 1/250 (0%)

Query: 9   SSEVDWCESNFQYSELVAEFYNTFSNIPFFIFGPLMMLLMHPYAQKRSRYIYVVWVLFMI 68
           SSEVDWCE N+     +AEFYNT SN+ FFI  P+ M L   YA   +  IY++W L ++
Sbjct: 14  SSEVDWCEDNYTIVPAIAEFYNTISNVLFFILPPICMCLFRQYATCFNSGIYLIWTLLVV 73

Query: 69  IGLFSMYFHMTLSFLGQLLDEIAILWLLGSGYSIWMPRCYFPSFLGGNRSQFIRLVFITT 128
           +G+ S+YFH TLSFLGQ+LDE+A+LW+L    ++W PR Y P     +R +F  +V + +
Sbjct: 74  VGIGSVYFHATLSFLGQMLDELAVLWVLMCALAMWFPRRYLPKIFRNDRGRFKVVVSVLS 133

Query: 129 VVSTLLSFLRPTVNAYALNSIALHILYIVCQEYRKTSNKELRHLIEVSVVLWAVALTSWI 188
            V+T L+F++P +N  +L ++ +    ++  E ++  N  +  L   S + W +AL  WI
Sbjct: 134 AVTTCLAFVKPAINNISLMTLGVPCTALLIAELKRCDNMRVFKLGLFSGLWWTLALFCWI 193

Query: 189 SDRLLCSFWQRIHFFYLHSIWHVLISITFPYGMVTMALVDANYEMPGETLKVRYWPRDSW 248
           SDR  C      +F YLH +WH+LI +    G V  A  DA  E+P +   +++WP + W
Sbjct: 194 SDRAFCELLSSFNFPYLHCMWHILICLAAYLGCVCFAYFDAASEIPEQGPVIKFWPNEKW 253

Query: 249 P-VGLPYVEI 257
             +G+PYV +
Sbjct: 254 AFIGVPYVSL 263


>gi|170932467 phytoceramidase, alkaline [Homo sapiens]
          Length = 267

 Score = 63.9 bits (154), Expect = 1e-10
 Identities = 64/265 (24%), Positives = 108/265 (40%), Gaps = 44/265 (16%)

Query: 9   SSEVDWCESNFQYSELVAEFYNTFSNIPFFIFGPLMMLLMHPYAQKRSRYIYVVWVLFMI 68
           +S +DWCE N+  +  +AEF+NT SN+   I  P+   +         RYI   ++   +
Sbjct: 15  TSTLDWCEENYSVTWYIAEFWNTVSNL-IMIIPPMFGAVQSVRDGLEKRYI-ASYLALTV 72

Query: 69  IGLFSMYFHMTLSFLGQLLDEIAILWLLGSGYSIWM-PRCYFPSFLGGNRSQF---IRLV 124
           +G+ S  FHMTL +  QLLDE+ ++      YS  +   C F  F   N   +     LV
Sbjct: 73  VGMGSWCFHMTLKYEMQLLDELPMI------YSCCIFVYCMFECFKIKNSVNYHLLFTLV 126

Query: 125 FITTVVSTLL-----SFLRPTVNAYALNSIALHILYIVCQEYRKTSNKELRHLIEVSVVL 179
             + +V+T+            +    + ++ L  +YIV   Y       LR L   S+ +
Sbjct: 127 LFSLIVTTVYLKVKEPIFHQVMYGMLVFTLVLRSIYIVTWVY-----PWLRGLGYTSLGI 181

Query: 180 WAVALTSWISDRLLCSFWQRIH---------FFYLHSIWHVLISITFPYGMVTMALVDAN 230
           + +    W  D + C   +                H+ WH+L  +         + +   
Sbjct: 182 FLLGFLFWNIDNIFCESLRNFRKKVPPIIGITTQFHAWWHILTGLG--------SYLHIL 233

Query: 231 YEMPGETLKVRYWPR-----DSWPV 250
           + +   TL +RY P+       WPV
Sbjct: 234 FSLYTRTLYLRYRPKVKFLFGIWPV 258


>gi|45439335 porcupine isoform D [Homo sapiens]
          Length = 461

 Score = 32.3 bits (72), Expect = 0.44
 Identities = 14/40 (35%), Positives = 24/40 (60%), Gaps = 2/40 (5%)

Query: 178 VLWAVALTSWI--SDRLLCSFWQRIHFFYLHSIWHVLISI 215
           +LW + L S++  +  +   F+   HFF LH +W VL+S+
Sbjct: 41  LLWRLGLPSYLKHASTVAGGFFSLYHFFQLHMVWVVLLSL 80


>gi|45439333 porcupine isoform C [Homo sapiens]
          Length = 455

 Score = 32.3 bits (72), Expect = 0.44
 Identities = 14/40 (35%), Positives = 24/40 (60%), Gaps = 2/40 (5%)

Query: 178 VLWAVALTSWI--SDRLLCSFWQRIHFFYLHSIWHVLISI 215
           +LW + L S++  +  +   F+   HFF LH +W VL+S+
Sbjct: 41  LLWRLGLPSYLKHASTVAGGFFSLYHFFQLHMVWVVLLSL 80


>gi|45439331 porcupine isoform B [Homo sapiens]
          Length = 456

 Score = 32.3 bits (72), Expect = 0.44
 Identities = 14/40 (35%), Positives = 24/40 (60%), Gaps = 2/40 (5%)

Query: 178 VLWAVALTSWI--SDRLLCSFWQRIHFFYLHSIWHVLISI 215
           +LW + L S++  +  +   F+   HFF LH +W VL+S+
Sbjct: 41  LLWRLGLPSYLKHASTVAGGFFSLYHFFQLHMVWVVLLSL 80


>gi|45439329 porcupine isoform A [Homo sapiens]
          Length = 450

 Score = 32.3 bits (72), Expect = 0.44
 Identities = 14/40 (35%), Positives = 24/40 (60%), Gaps = 2/40 (5%)

Query: 178 VLWAVALTSWI--SDRLLCSFWQRIHFFYLHSIWHVLISI 215
           +LW + L S++  +  +   F+   HFF LH +W VL+S+
Sbjct: 41  LLWRLGLPSYLKHASTVAGGFFSLYHFFQLHMVWVVLLSL 80


>gi|110556646 transmembrane protein 8B isoform a [Homo sapiens]
          Length = 472

 Score = 30.0 bits (66), Expect = 2.2
 Identities = 10/16 (62%), Positives = 15/16 (93%)

Query: 199 RIHFFYLHSIWHVLIS 214
           R ++FY+HSIWH+LI+
Sbjct: 403 RDNYFYIHSIWHMLIA 418


>gi|110556642 transmembrane protein 8B isoform a [Homo sapiens]
          Length = 472

 Score = 30.0 bits (66), Expect = 2.2
 Identities = 10/16 (62%), Positives = 15/16 (93%)

Query: 199 RIHFFYLHSIWHVLIS 214
           R ++FY+HSIWH+LI+
Sbjct: 403 RDNYFYIHSIWHMLIA 418


>gi|148276981 transmembrane protein 184A [Homo sapiens]
          Length = 413

 Score = 29.3 bits (64), Expect = 3.7
 Identities = 22/103 (21%), Positives = 48/103 (46%), Gaps = 6/103 (5%)

Query: 115 GNRSQFIRLVFITTVVSTLLSFLRPTVNAYALNSIALHILYIVCQEYRKTSNKELRHLIE 174
           GN SQ    +F+T+ ++  +S     +  +    +  H +Y+  + Y  T  +E R++I 
Sbjct: 39  GNSSQGAPWLFLTSALARGVS----GIFVWTALVLTCHQIYLHLRSY--TVPQEQRYIIR 92

Query: 175 VSVVLWAVALTSWISDRLLCSFWQRIHFFYLHSIWHVLISITF 217
           + +++   A  SW+S  LL      ++F  +   +   +  +F
Sbjct: 93  LLLIVPIYAFDSWLSLLLLGDHQYYVYFDSVRDCYEAFVIYSF 135


>gi|12965180 taste receptor, type 2, member 10 [Homo sapiens]
          Length = 307

 Score = 29.3 bits (64), Expect = 3.7
 Identities = 23/119 (19%), Positives = 50/119 (42%), Gaps = 18/119 (15%)

Query: 59  IYVVWVLFMIIGLFSMYFHMTLSFLGQLLDEIAILWLLGSGYSIWMPRC----------- 107
           I+++W++  I   F   F   +   G L++ I+  W++G+  S+W               
Sbjct: 55  IFLIWII--ITDGFIQIFSPNIYASGNLIEYISYFWVIGNQSSMWFATSLSIFYFLKIAN 112

Query: 108 ---YFPSFLGGNRSQFIRLVFITTVVSTLLSF--LRPTVNAYALNSIALHILYIVCQEY 161
              Y   +L    +  +  + +  ++S+LL+F  +   +N Y   +  +  L +   EY
Sbjct: 113 FSNYIFLWLKSRTNMVLPFMIVFLLISSLLNFAYIAKILNDYKTKNDTVWDLNMYKSEY 171


>gi|30039714 otopetrin 2 [Homo sapiens]
          Length = 562

 Score = 28.9 bits (63), Expect = 4.8
 Identities = 17/57 (29%), Positives = 30/57 (52%), Gaps = 11/57 (19%)

Query: 172 LIEVSVVLWAVALTSWISDRLLCSFWQRIHF-------FYLHSIWHVLISITFPYGM 221
           L ++S+ L    +  WI    + +F  R HF       FY +S+W V+++I  P+G+
Sbjct: 493 LKDISLFLLLCNVILWI----MPAFGARPHFSNTVEVDFYGYSLWAVIVNICLPFGI 545


>gi|4885361 gastrin-releasing peptide receptor [Homo sapiens]
          Length = 384

 Score = 28.5 bits (62), Expect = 6.3
 Identities = 15/47 (31%), Positives = 26/47 (55%), Gaps = 8/47 (17%)

Query: 123 LVFITTVVSTLLSFLRPTVNAYALNSIALHILYIVCQEYRKTSNKEL 169
           L F+T++ + LL+F    VN +A        LY++ + +RK  N +L
Sbjct: 299 LHFVTSICARLLAFTNSCVNPFA--------LYLLSKSFRKQFNTQL 337


>gi|239757761 PREDICTED: similar to gastrin-releasing peptide
           receptor [Homo sapiens]
          Length = 368

 Score = 28.5 bits (62), Expect = 6.3
 Identities = 15/47 (31%), Positives = 26/47 (55%), Gaps = 8/47 (17%)

Query: 123 LVFITTVVSTLLSFLRPTVNAYALNSIALHILYIVCQEYRKTSNKEL 169
           L F+T++ + LL+F    VN +A        LY++ + +RK  N +L
Sbjct: 283 LHFVTSICARLLAFTNSCVNPFA--------LYLLSKSFRKQFNTQL 321


>gi|21536357 TBP-associated factor 6 isoform delta [Homo sapiens]
          Length = 667

 Score = 28.5 bits (62), Expect = 6.3
 Identities = 18/63 (28%), Positives = 29/63 (46%), Gaps = 2/63 (3%)

Query: 126 ITTVVSTLLSFLRPTV-NAYALNSIALHILYIVCQEYRKTSNKELRHLIEVSVVLWAVAL 184
           +T +VS  L  LRP V N +AL   A  ++  +C+ +  T+N     + +     W    
Sbjct: 299 MTCIVSRQLC-LRPDVDNHWALRDFAARLVAQICKHFSTTTNNIQSRITKTFTKSWVDEK 357

Query: 185 TSW 187
           T W
Sbjct: 358 TPW 360


>gi|21536355 TBP-associated factor 6 isoform gamma [Homo sapiens]
          Length = 667

 Score = 28.5 bits (62), Expect = 6.3
 Identities = 18/63 (28%), Positives = 29/63 (46%), Gaps = 2/63 (3%)

Query: 126 ITTVVSTLLSFLRPTV-NAYALNSIALHILYIVCQEYRKTSNKELRHLIEVSVVLWAVAL 184
           +T +VS  L  LRP V N +AL   A  ++  +C+ +  T+N     + +     W    
Sbjct: 309 MTCIVSRQLC-LRPDVDNHWALRDFAARLVAQICKHFSTTTNNIQSRITKTFTKSWVDEK 367

Query: 185 TSW 187
           T W
Sbjct: 368 TPW 370


>gi|5032147 TBP-associated factor 6 isoform alpha [Homo sapiens]
          Length = 677

 Score = 28.5 bits (62), Expect = 6.3
 Identities = 18/63 (28%), Positives = 29/63 (46%), Gaps = 2/63 (3%)

Query: 126 ITTVVSTLLSFLRPTV-NAYALNSIALHILYIVCQEYRKTSNKELRHLIEVSVVLWAVAL 184
           +T +VS  L  LRP V N +AL   A  ++  +C+ +  T+N     + +     W    
Sbjct: 309 MTCIVSRQLC-LRPDVDNHWALRDFAARLVAQICKHFSTTTNNIQSRITKTFTKSWVDEK 367

Query: 185 TSW 187
           T W
Sbjct: 368 TPW 370


>gi|21536359 TBP-associated factor 6 isoform alpha [Homo sapiens]
          Length = 677

 Score = 28.5 bits (62), Expect = 6.3
 Identities = 18/63 (28%), Positives = 29/63 (46%), Gaps = 2/63 (3%)

Query: 126 ITTVVSTLLSFLRPTV-NAYALNSIALHILYIVCQEYRKTSNKELRHLIEVSVVLWAVAL 184
           +T +VS  L  LRP V N +AL   A  ++  +C+ +  T+N     + +     W    
Sbjct: 309 MTCIVSRQLC-LRPDVDNHWALRDFAARLVAQICKHFSTTTNNIQSRITKTFTKSWVDEK 367

Query: 185 TSW 187
           T W
Sbjct: 368 TPW 370


>gi|46409372 G protein-coupled receptor 153 [Homo sapiens]
          Length = 609

 Score = 28.1 bits (61), Expect = 8.2
 Identities = 22/111 (19%), Positives = 46/111 (41%), Gaps = 10/111 (9%)

Query: 124 VFITTVVSTLLSFLRPTVNAYALNSIALHILYIVCQEYRKTSNKELRHLIEVSVVLWAVA 183
           VF++T  +  L+        +++ S++ H +++VC       +   +  +   + +W V 
Sbjct: 85  VFVSTFYTLTLA------TCFSVTSLSYHRMWMVCWPVNYRLSNAKKQAVHTVMGIWMV- 137

Query: 184 LTSWISDRLLCSFW-QRIHFFYLHSIWHVLISITFPYGMVTMALVDANYEM 233
             S+I   L    W      FY H    ++  I   +G+  + LV  +  M
Sbjct: 138 --SFILSALPAVGWHDTSERFYTHGCRFIVAEIGLGFGVCFLLLVGGSVAM 186


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.331    0.142    0.473 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,562,397
Number of Sequences: 37866
Number of extensions: 379772
Number of successful extensions: 892
Number of sequences better than 10.0: 19
Number of HSP's better than 10.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 882
Number of HSP's gapped (non-prelim): 19
length of query: 264
length of database: 18,247,518
effective HSP length: 100
effective length of query: 164
effective length of database: 14,460,918
effective search space: 2371590552
effective search space used: 2371590552
T: 11
A: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.9 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.