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Search of human proteins with 193794853
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|193794853 premature ovarian failure, 1B [Homo sapiens]
(589 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|193794853 premature ovarian failure, 1B [Homo sapiens] 1200 0.0
gi|203096856 kinesin family member 7 [Homo sapiens] 59 1e-08
gi|70166430 GRINL1A combined protein isoform 2 [Homo sapiens] 58 2e-08
gi|70166414 GRINL1A combined protein isoform 1 [Homo sapiens] 58 2e-08
gi|111494235 GRINL1A combined protein isoform 8 [Homo sapiens] 58 2e-08
gi|70166580 GRINL1A upstream protein isoform 7 [Homo sapiens] 58 2e-08
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [... 57 5e-08
gi|109659847 filamin A interacting protein 1-like isoform 3 [Hom... 56 1e-07
gi|109659845 filamin A interacting protein 1-like isoform 1 [Hom... 56 1e-07
gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo... 56 1e-07
gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo... 56 1e-07
gi|109659849 filamin A interacting protein 1-like isoform 2 [Hom... 55 1e-07
gi|55770834 centromere protein F [Homo sapiens] 55 1e-07
gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo ... 55 2e-07
gi|31542634 filamin A interacting protein 1 [Homo sapiens] 54 4e-07
gi|118498362 kinectin 1 isoform b [Homo sapiens] 54 5e-07
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 54 5e-07
gi|150010604 kinesin family member 4B [Homo sapiens] 53 9e-07
gi|58530842 desmoplakin isoform II [Homo sapiens] 52 1e-06
gi|36031016 CTCL tumor antigen L14-2 [Homo sapiens] 52 1e-06
gi|38044112 restin isoform b [Homo sapiens] 52 2e-06
gi|4506751 restin isoform a [Homo sapiens] 52 2e-06
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo... 52 2e-06
gi|190341068 forkhead-associated (FHA) phosphopeptide binding do... 52 2e-06
gi|46049114 M-phase phosphoprotein 1 [Homo sapiens] 52 2e-06
gi|112420968 coiled-coil domain containing 158 [Homo sapiens] 52 2e-06
gi|58530840 desmoplakin isoform I [Homo sapiens] 51 3e-06
gi|41872583 Rho-associated, coiled-coil containing protein kinas... 51 3e-06
gi|237858621 polyamine modulated factor 1 binding protein 1 isof... 51 3e-06
gi|237858619 polyamine modulated factor 1 binding protein 1 isof... 51 3e-06
>gi|193794853 premature ovarian failure, 1B [Homo sapiens]
Length = 589
Score = 1200 bits (3105), Expect = 0.0
Identities = 589/589 (100%), Positives = 589/589 (100%)
Query: 1 MSSSYWSETSSSSCGTQQLPEVLQCQPQHYHCYHQSSQAQQPPEKNVVYERVRTYSGPMN 60
MSSSYWSETSSSSCGTQQLPEVLQCQPQHYHCYHQSSQAQQPPEKNVVYERVRTYSGPMN
Sbjct: 1 MSSSYWSETSSSSCGTQQLPEVLQCQPQHYHCYHQSSQAQQPPEKNVVYERVRTYSGPMN 60
Query: 61 KVVQALDPFNSREVLSPLKTTSSYQNLVWSDHSQELHSPTLKISTCAPSTLHITQNTEQE 120
KVVQALDPFNSREVLSPLKTTSSYQNLVWSDHSQELHSPTLKISTCAPSTLHITQNTEQE
Sbjct: 61 KVVQALDPFNSREVLSPLKTTSSYQNLVWSDHSQELHSPTLKISTCAPSTLHITQNTEQE 120
Query: 121 LHSPTVKLTTYPQTTIRKYVVQNPEQEPLSQFLRGSHFFPGNNVIYEKTIRKVEKLNTDQ 180
LHSPTVKLTTYPQTTIRKYVVQNPEQEPLSQFLRGSHFFPGNNVIYEKTIRKVEKLNTDQ
Sbjct: 121 LHSPTVKLTTYPQTTIRKYVVQNPEQEPLSQFLRGSHFFPGNNVIYEKTIRKVEKLNTDQ 180
Query: 181 GCHPQAQCHHHIIQQPQVIHSAHWQQPDSSQQIQAITGNNPISTHIGNELCHSGSSQICE 240
GCHPQAQCHHHIIQQPQVIHSAHWQQPDSSQQIQAITGNNPISTHIGNELCHSGSSQICE
Sbjct: 181 GCHPQAQCHHHIIQQPQVIHSAHWQQPDSSQQIQAITGNNPISTHIGNELCHSGSSQICE 240
Query: 241 QVIIQDDGPEKLDPRYFGELLADLSRKNTDLYHCLLEHLQRIGGSKQDFESTDESEDIES 300
QVIIQDDGPEKLDPRYFGELLADLSRKNTDLYHCLLEHLQRIGGSKQDFESTDESEDIES
Sbjct: 241 QVIIQDDGPEKLDPRYFGELLADLSRKNTDLYHCLLEHLQRIGGSKQDFESTDESEDIES 300
Query: 301 LIPKGLSEFTKQQIRYILQMRGMSDKSLRLVLSTFSNIREELGHLQNDMTSLENDKMRLE 360
LIPKGLSEFTKQQIRYILQMRGMSDKSLRLVLSTFSNIREELGHLQNDMTSLENDKMRLE
Sbjct: 301 LIPKGLSEFTKQQIRYILQMRGMSDKSLRLVLSTFSNIREELGHLQNDMTSLENDKMRLE 360
Query: 361 KDLSFKDTQLKEYEELLASVRANNHQQQQGLQDSSSKCQALEENNLSLRHTLSDMEYRLK 420
KDLSFKDTQLKEYEELLASVRANNHQQQQGLQDSSSKCQALEENNLSLRHTLSDMEYRLK
Sbjct: 361 KDLSFKDTQLKEYEELLASVRANNHQQQQGLQDSSSKCQALEENNLSLRHTLSDMEYRLK 420
Query: 421 ELEYCKRNLEQENQNLRMQVSETCTGPMLQAKMDEIGNHYTEMVKNLRMEKDREICRLRS 480
ELEYCKRNLEQENQNLRMQVSETCTGPMLQAKMDEIGNHYTEMVKNLRMEKDREICRLRS
Sbjct: 421 ELEYCKRNLEQENQNLRMQVSETCTGPMLQAKMDEIGNHYTEMVKNLRMEKDREICRLRS 480
Query: 481 QLNQYHKDVSKREGSCSDFQFKLHELTSLLEEKDSLIKRQSEELSKLRQEIYSSHNQPST 540
QLNQYHKDVSKREGSCSDFQFKLHELTSLLEEKDSLIKRQSEELSKLRQEIYSSHNQPST
Sbjct: 481 QLNQYHKDVSKREGSCSDFQFKLHELTSLLEEKDSLIKRQSEELSKLRQEIYSSHNQPST 540
Query: 541 GGRTTITTKKYRTQYPILGLLYDDYEYIPPGSETQTIVIEKTEDKYTCP 589
GGRTTITTKKYRTQYPILGLLYDDYEYIPPGSETQTIVIEKTEDKYTCP
Sbjct: 541 GGRTTITTKKYRTQYPILGLLYDDYEYIPPGSETQTIVIEKTEDKYTCP 589
>gi|203096856 kinesin family member 7 [Homo sapiens]
Length = 1343
Score = 59.3 bits (142), Expect = 1e-08
Identities = 60/234 (25%), Positives = 108/234 (46%), Gaps = 22/234 (9%)
Query: 311 KQQIRYILQMRGMSDKSLRLVLSTFSNIREELGHLQNDMTSLENDKMRLEKDLSFKDTQL 370
KQ ++ + S+K L+ + +R++ G LQ + K RLE ++S + ++
Sbjct: 804 KQATERLVSLSAQSEKRLQELERNVQLMRQQQGQLQRRLREETEQKRRLEAEMSKRQHRV 863
Query: 371 KEYEELLASVRANNHQQQQGLQDSSSKCQALEENNLSLRHTLSDMEYRLKELEYCKRNLE 430
KE E + QQQ+ L+ + + A + S + + +++E K+ L+
Sbjct: 864 KELE-------LKHEQQQKILKIKTEEIAAFQRKRRSGSNGSVVSLEQQQKIEEQKKWLD 916
Query: 431 QENQNLRMQ-------VSETCTGPMLQAKMDEIGNHYTEM-VKNLRMEK--DREICRLRS 480
QE + + Q E + AK + + T + K LR + + +I R+ S
Sbjct: 917 QEMEKVLQQRRALEELGEELHKREAILAKKEALMQEKTGLESKRLRSSQALNEDIVRVSS 976
Query: 481 QLNQYHKDVSK-----REGSCSDFQFKLHELTSLLEEKDSLIKRQSEELSKLRQ 529
+L K++S+ R+GS Q E+ SL +EKDSL+K++ E KLRQ
Sbjct: 977 RLEHLEKELSEKSGQLRQGSAQSQQQIRGEIDSLRQEKDSLLKQRLEIDGKLRQ 1030
Score = 33.9 bits (76), Expect = 0.43
Identities = 37/178 (20%), Positives = 76/178 (42%), Gaps = 17/178 (9%)
Query: 374 EELLASVRANNHQQQQGLQDSSSKCQALEENNLSLRHTLSDMEYRLKELEYCKRNLEQEN 433
EEL+ + Q + S + + LE+ +R LS+ + +L+ELE + L+
Sbjct: 721 EELIGELVRTGKAAQALNRQHSQRIRELEQEAEQVRAELSEGQRQLRELE--GKELQDAG 778
Query: 434 QNLRMQ-VSETCTGPMLQAKMDEIGNHYTEMVKNLR-------MEKDREICRLRSQLNQY 485
+ R+Q Q ++ + TE + +L E +R + +R Q Q
Sbjct: 779 ERSRLQEFRRRVAAAQSQVQVLKEKKQATERLVSLSAQSEKRLQELERNVQLMRQQQGQL 838
Query: 486 HKDVSKR-------EGSCSDFQFKLHELTSLLEEKDSLIKRQSEELSKLRQEIYSSHN 536
+ + + E S Q ++ EL E++ ++K ++EE++ +++ S N
Sbjct: 839 QRRLREETEQKRRLEAEMSKRQHRVKELELKHEQQQKILKIKTEEIAAFQRKRRSGSN 896
>gi|70166430 GRINL1A combined protein isoform 2 [Homo sapiens]
Length = 445
Score = 58.2 bits (139), Expect = 2e-08
Identities = 45/263 (17%), Positives = 120/263 (45%), Gaps = 3/263 (1%)
Query: 292 TDESEDIESLIPKGLSEFTKQQIRYILQMRGMSDKSLRLVLSTFSNIREELGHLQNDMTS 351
+D+++ E ++ + K+++ YI +R +K + + + +R+++ L +++
Sbjct: 79 SDQNQQKEMVVYGWSTSQLKEEMNYIKDVRATLEKVRKRMYGDYDEMRQKIRQLTQELSV 138
Query: 352 LENDKMRLEKDLSFKDTQLKEYEELLASVRANNHQQQQGLQDSSSKCQALEENNLSLRHT 411
+ LE + + + L + + +++ +++ Q+ L D + + +++ +L+ T
Sbjct: 139 SHAQQEYLENHIQTQSSALDRFNAMNSALASDSIGLQKTLVDVTLENSNIKDQIRNLQQT 198
Query: 412 LSDMEYRLKELEYCKRNLEQENQNLRMQV--SETCTGPMLQAKMDEIGNHYTEMVKNLRM 469
+L+E + + ENQ L+M+V S+ +++ ++ + Y E ++ +
Sbjct: 199 YEASMDKLREKQRQLEVAQVENQLLKMKVESSQEANAEVMREMTKKLYSQYEEKLQEEQR 258
Query: 470 EKDREICRLRSQLNQYHKDVSKREGSCSDFQFKLHELTSLLEEKDSLIKRQSEELSKLRQ 529
+ E L + N + K + + + L E + E D LI+R +E +L+
Sbjct: 259 KHSAEKEALLEETNSFLKAIEEANKKMQAAEISLEEKDQRIGELDRLIERMEKERHQLQL 318
Query: 530 EIYSSHNQPSTGGRTTITTKKYR 552
++ H +G T ++Y+
Sbjct: 319 QLL-EHETEMSGELTDSDKERYQ 340
>gi|70166414 GRINL1A combined protein isoform 1 [Homo sapiens]
Length = 550
Score = 58.2 bits (139), Expect = 2e-08
Identities = 45/263 (17%), Positives = 120/263 (45%), Gaps = 3/263 (1%)
Query: 292 TDESEDIESLIPKGLSEFTKQQIRYILQMRGMSDKSLRLVLSTFSNIREELGHLQNDMTS 351
+D+++ E ++ + K+++ YI +R +K + + + +R+++ L +++
Sbjct: 79 SDQNQQKEMVVYGWSTSQLKEEMNYIKDVRATLEKVRKRMYGDYDEMRQKIRQLTQELSV 138
Query: 352 LENDKMRLEKDLSFKDTQLKEYEELLASVRANNHQQQQGLQDSSSKCQALEENNLSLRHT 411
+ LE + + + L + + +++ +++ Q+ L D + + +++ +L+ T
Sbjct: 139 SHAQQEYLENHIQTQSSALDRFNAMNSALASDSIGLQKTLVDVTLENSNIKDQIRNLQQT 198
Query: 412 LSDMEYRLKELEYCKRNLEQENQNLRMQV--SETCTGPMLQAKMDEIGNHYTEMVKNLRM 469
+L+E + + ENQ L+M+V S+ +++ ++ + Y E ++ +
Sbjct: 199 YEASMDKLREKQRQLEVAQVENQLLKMKVESSQEANAEVMREMTKKLYSQYEEKLQEEQR 258
Query: 470 EKDREICRLRSQLNQYHKDVSKREGSCSDFQFKLHELTSLLEEKDSLIKRQSEELSKLRQ 529
+ E L + N + K + + + L E + E D LI+R +E +L+
Sbjct: 259 KHSAEKEALLEETNSFLKAIEEANKKMQAAEISLEEKDQRIGELDRLIERMEKERHQLQL 318
Query: 530 EIYSSHNQPSTGGRTTITTKKYR 552
++ H +G T ++Y+
Sbjct: 319 QLL-EHETEMSGELTDSDKERYQ 340
>gi|111494235 GRINL1A combined protein isoform 8 [Homo sapiens]
Length = 438
Score = 58.2 bits (139), Expect = 2e-08
Identities = 45/263 (17%), Positives = 120/263 (45%), Gaps = 3/263 (1%)
Query: 292 TDESEDIESLIPKGLSEFTKQQIRYILQMRGMSDKSLRLVLSTFSNIREELGHLQNDMTS 351
+D+++ E ++ + K+++ YI +R +K + + + +R+++ L +++
Sbjct: 79 SDQNQQKEMVVYGWSTSQLKEEMNYIKDVRATLEKVRKRMYGDYDEMRQKIRQLTQELSV 138
Query: 352 LENDKMRLEKDLSFKDTQLKEYEELLASVRANNHQQQQGLQDSSSKCQALEENNLSLRHT 411
+ LE + + + L + + +++ +++ Q+ L D + + +++ +L+ T
Sbjct: 139 SHAQQEYLENHIQTQSSALDRFNAMNSALASDSIGLQKTLVDVTLENSNIKDQIRNLQQT 198
Query: 412 LSDMEYRLKELEYCKRNLEQENQNLRMQV--SETCTGPMLQAKMDEIGNHYTEMVKNLRM 469
+L+E + + ENQ L+M+V S+ +++ ++ + Y E ++ +
Sbjct: 199 YEASMDKLREKQRQLEVAQVENQLLKMKVESSQEANAEVMREMTKKLYSQYEEKLQEEQR 258
Query: 470 EKDREICRLRSQLNQYHKDVSKREGSCSDFQFKLHELTSLLEEKDSLIKRQSEELSKLRQ 529
+ E L + N + K + + + L E + E D LI+R +E +L+
Sbjct: 259 KHSAEKEALLEETNSFLKAIEEANKKMQAAEISLEEKDQRIGELDRLIERMEKERHQLQL 318
Query: 530 EIYSSHNQPSTGGRTTITTKKYR 552
++ H +G T ++Y+
Sbjct: 319 QLL-EHETEMSGELTDSDKERYQ 340
>gi|70166580 GRINL1A upstream protein isoform 7 [Homo sapiens]
Length = 466
Score = 58.2 bits (139), Expect = 2e-08
Identities = 45/263 (17%), Positives = 120/263 (45%), Gaps = 3/263 (1%)
Query: 292 TDESEDIESLIPKGLSEFTKQQIRYILQMRGMSDKSLRLVLSTFSNIREELGHLQNDMTS 351
+D+++ E ++ + K+++ YI +R +K + + + +R+++ L +++
Sbjct: 79 SDQNQQKEMVVYGWSTSQLKEEMNYIKDVRATLEKVRKRMYGDYDEMRQKIRQLTQELSV 138
Query: 352 LENDKMRLEKDLSFKDTQLKEYEELLASVRANNHQQQQGLQDSSSKCQALEENNLSLRHT 411
+ LE + + + L + + +++ +++ Q+ L D + + +++ +L+ T
Sbjct: 139 SHAQQEYLENHIQTQSSALDRFNAMNSALASDSIGLQKTLVDVTLENSNIKDQIRNLQQT 198
Query: 412 LSDMEYRLKELEYCKRNLEQENQNLRMQV--SETCTGPMLQAKMDEIGNHYTEMVKNLRM 469
+L+E + + ENQ L+M+V S+ +++ ++ + Y E ++ +
Sbjct: 199 YEASMDKLREKQRQLEVAQVENQLLKMKVESSQEANAEVMREMTKKLYSQYEEKLQEEQR 258
Query: 470 EKDREICRLRSQLNQYHKDVSKREGSCSDFQFKLHELTSLLEEKDSLIKRQSEELSKLRQ 529
+ E L + N + K + + + L E + E D LI+R +E +L+
Sbjct: 259 KHSAEKEALLEETNSFLKAIEEANKKMQAAEISLEEKDQRIGELDRLIERMEKERHQLQL 318
Query: 530 EIYSSHNQPSTGGRTTITTKKYR 552
++ H +G T ++Y+
Sbjct: 319 QLL-EHETEMSGELTDSDKERYQ 340
>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo
sapiens]
Length = 1937
Score = 57.0 bits (136), Expect = 5e-08
Identities = 57/321 (17%), Positives = 138/321 (42%), Gaps = 40/321 (12%)
Query: 209 SSQQIQAITGNNPISTHIGNELCHSGSSQICEQVIIQDDGPEKLDPRYFGELLADLSRKN 268
S+QQI+ + T N L H+ S + ++++ E+ + + EL LS+ N
Sbjct: 1311 STQQIEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEGK--AELQRALSKAN 1368
Query: 269 TDLYHCLLEHLQRIGGSKQDFESTDESEDIESLIPKGLSEFTKQQIRYILQMRGMSDKSL 328
+++ ++ + T+E E+ + + + L E +++ +
Sbjct: 1369 SEVAQWRTKY------ETDAIQRTEELEEAKKKLAQRLQE---------------AEEHV 1407
Query: 329 RLVLSTFSNIREELGHLQNDMTSLENDKMRLEKDLSFKDTQLKEYEELLASVRANNHQQQ 388
V + +++ + LQN++ L D R + D + + ++++L+ + + Q
Sbjct: 1408 EAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQ 1467
Query: 389 QGLQDSSSKCQALEENNLSLRHTLSDMEYRLKELEYCKRNLEQENQNLRMQVSETCTGPM 448
L+ S + ++L +++ + +L+ L +NL+QE +L Q++E
Sbjct: 1468 AELEASQKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEISDLTEQIAE------ 1521
Query: 449 LQAKMDEIGNHYTEMVKNLRMEKDREICRLRSQLNQYHKDVSKREGSCSDFQFKLHELTS 508
G ++ ++ + ++E C +++ L + + EG Q +L+++ S
Sbjct: 1522 --------GGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKS 1573
Query: 509 LLEEKDSLIKRQSEELSKLRQ 529
E D I + EE+ +L++
Sbjct: 1574 ---EVDRKIAEKDEEIDQLKR 1591
Score = 47.8 bits (112), Expect = 3e-05
Identities = 56/233 (24%), Positives = 101/233 (43%), Gaps = 44/233 (18%)
Query: 339 REELGHLQNDMTSLENDKMRLEKDLSFKDTQLK-EYEELLASVRANNHQQQQGLQDSSSK 397
R +L H QN TSL N K +LE D+S QL+ E EE++ R + ++ + D++
Sbjct: 1715 RVQLLHTQN--TSLINTKKKLENDVS----QLQSEVEEVIQESRNAEEKAKKAITDAAMM 1768
Query: 398 CQAL----------EENNLSLRHTLSDMEYRLKELEYCK-RNLEQENQNLRMQVSETCTG 446
+ L E +L T+ D+++RL E E + +++ Q L +V E
Sbjct: 1769 AEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRE---- 1824
Query: 447 PMLQAKMDEIGNHYTEMVKNLRM------------EKDRE--------ICRLRSQLNQYH 486
L+ +++ E VK LR E+DR+ + +L++++ Y
Sbjct: 1825 --LEGEVENEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQAKVKSYK 1882
Query: 487 KDVSKREGSCSDFQFKLHELTSLLEEKDSLIKRQSEELSKLRQEIYSSHNQPS 539
+ + E + K +L LEE + +++KLR + H + S
Sbjct: 1883 RQAEEAEEQSNANLSKFRKLQHELEEAEERADIAESQVNKLRVKSREVHTKIS 1935
Score = 44.3 bits (103), Expect = 3e-04
Identities = 46/227 (20%), Positives = 96/227 (42%), Gaps = 18/227 (7%)
Query: 323 MSDKSLRLVLSTFSNIREELGHLQNDMTSLENDKMRL---EKDLSFKDTQLKEYEELLAS 379
++ +SLR +T ++E HL + + E+ K +L E+ + +++E L
Sbjct: 1638 LAAESLRNYRNTQGILKETQLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELWATLEQ 1697
Query: 380 VRANNHQQQQGLQDSSSKCQALEENNLSLRHTLSDMEYRLKELEYCKRNLEQENQNLRMQ 439
+ +Q L D+S + Q L N SL +T +E + +L+ + QE++N +
Sbjct: 1698 TERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQESRNAEEK 1757
Query: 440 VSETCTGPMLQA----KMDEIGNHYTEMVKNL---------RMEKDREICRL--RSQLNQ 484
+ T + A K + H M KNL R+++ ++ + Q+ +
Sbjct: 1758 AKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQK 1817
Query: 485 YHKDVSKREGSCSDFQFKLHELTSLLEEKDSLIKRQSEELSKLRQEI 531
V + EG + Q + E L + + +K + + + R+ +
Sbjct: 1818 LEARVRELEGEVENEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNV 1864
Score = 41.2 bits (95), Expect = 0.003
Identities = 57/276 (20%), Positives = 115/276 (41%), Gaps = 36/276 (13%)
Query: 286 KQDFESTDESEDIESLIPKGLSEFTKQQIRYILQMRGM--SDKSLRLVLSTFSNIRE-EL 342
+Q + ED +++ K ++ +Q + + G +K LR+ L E +L
Sbjct: 1007 QQTLDDLQAEEDKVNILTKAKTKLEQQ----VDDLEGSLEQEKKLRMDLERAKRKLEGDL 1062
Query: 343 GHLQNDMTSLENDKMRLEKDLSFKDTQLKEYEELLASVRANNHQQQQGLQDSSSKCQAL- 401
Q +ENDK +L++ L K+ ++ + +A Q Q+ +++ ++ + L
Sbjct: 1063 KLAQESTMDMENDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELG 1122
Query: 402 -------------EENNLSLRHTLSDMEYRLKE--------LEYCKRNLEQENQNLRMQV 440
E+ L L ++ RL+E +E K+ E E Q LR +
Sbjct: 1123 EEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQVELNKKR-EAEFQKLRRDL 1181
Query: 441 SET-----CTGPMLQAKMDEIGNHYTEMVKNLRMEKDREICRLRSQLNQYHKDVSKREGS 495
E L+ K + E + NL+ K +++ + +S+L D+S +
Sbjct: 1182 EEATLQHEAMVAALRKKHADSMAELGEQIDNLQRVK-QKLEKEKSELKMETDDLSSNAEA 1240
Query: 496 CSDFQFKLHELTSLLEEKDSLIKRQSEELSKLRQEI 531
S + L ++ LE++ S +K + EE +L ++
Sbjct: 1241 ISKAKGNLEKMCRSLEDQVSELKTKEEEQQRLINDL 1276
Score = 35.4 bits (80), Expect = 0.15
Identities = 40/213 (18%), Positives = 89/213 (41%), Gaps = 25/213 (11%)
Query: 340 EELGHLQNDMTSLENDKMRLEKDLSFKDTQLKEYEELLASVRANNHQQQQGLQDSSSKCQ 399
EELG ++ + + + EK S +L+E E L Q + + ++ Q
Sbjct: 1119 EELGE---EIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQVELNKKREAEFQ 1175
Query: 400 ALEEN--NLSLRH-------------TLSDMEYRLKELEYCKRNLEQENQNLRMQVSETC 444
L + +L+H +++++ ++ L+ K+ LE+E L+M+ +
Sbjct: 1176 KLRRDLEEATLQHEAMVAALRKKHADSMAELGEQIDNLQRVKQKLEKEKSELKMETDD-- 1233
Query: 445 TGPMLQAKMDEIGNHYTEMVKNLRMEKDREICRLRSQLNQYHKDVSKREGSCSDFQFKLH 504
L + + I + K R +D ++ L+++ + + ++ + Q +
Sbjct: 1234 ----LSSNAEAISKAKGNLEKMCRSLED-QVSELKTKEEEQQRLINDLTAQRARLQTEAG 1288
Query: 505 ELTSLLEEKDSLIKRQSEELSKLRQEIYSSHNQ 537
E + L+EKD+L+ + S Q+I +Q
Sbjct: 1289 EYSRQLDEKDALVSQLSRSKQASTQQIEELKHQ 1321
Score = 33.5 bits (75), Expect = 0.56
Identities = 44/262 (16%), Positives = 98/262 (37%), Gaps = 21/262 (8%)
Query: 293 DESEDIESLIPKGLSEFTKQQIRYILQMRGMSDKSLRLVLSTFSNIREELGHLQNDMTSL 352
DE + + S + + T QQI + K+ + + R + L+
Sbjct: 1295 DEKDALVSQLSRSKQAST-QQIEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEEE 1353
Query: 353 ENDKMRLEKDLSFKDTQLKEYEELLASVRANNHQQQQGLQDSSSKCQALEENNLSLRHTL 412
+ K L++ LS ++++ ++ + D+ + + LEE L L
Sbjct: 1354 QEGKAELQRALSKANSEVAQWRTKYET-------------DAIQRTEELEEAKKKLAQRL 1400
Query: 413 SDMEYRLKELEYCKRNLEQENQNLRMQVSETCTGPMLQAKMDEIGNHYTEMVKNLRMEKD 472
+ E ++ + +LE+ Q L+ +V + ML E N + + D
Sbjct: 1401 QEAEEHVEAVNAKCASLEKTKQRLQNEVEDL----MLDV---ERSNAACAALDKKQRNFD 1453
Query: 473 REICRLRSQLNQYHKDVSKREGSCSDFQFKLHELTSLLEEKDSLIKRQSEELSKLRQEIY 532
+ + + + + ++ + +L ++ ++ EE ++ E L+QEI
Sbjct: 1454 KVLSEWKQKYEETQAELEASQKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEIS 1513
Query: 533 SSHNQPSTGGRTTITTKKYRTQ 554
Q + GG+ +K + Q
Sbjct: 1514 DLTEQIAEGGKQIHELEKIKKQ 1535
Score = 32.0 bits (71), Expect = 1.6
Identities = 45/229 (19%), Positives = 92/229 (40%), Gaps = 31/229 (13%)
Query: 324 SDKSLRLVLSTFSNIREELG-------HLQNDMTSLENDKMRLEKDLSFKDTQLKEYEEL 376
++K + + F ++EL L+ M +L +K L+ + + L + EE
Sbjct: 848 TEKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLADAEER 907
Query: 377 LASVRANNHQQQQGLQDSSSKCQALEENNLSL--------------RHTLSDMEYRLKEL 422
+ N Q + +++ + + + EE N L + + D+E L ++
Sbjct: 908 CEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKV 967
Query: 423 EYCKRNLEQENQNLRMQVSETC-TGPMLQAKMDEIGNHYTEMVKNLRMEKDREICRLRSQ 481
E K E + +NL +++ T L + + + + + +L+ E+D+
Sbjct: 968 EKEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDK-------- 1019
Query: 482 LNQYHKDVSKREGSCSDFQFKLHELTSLLEEKDSLIKRQSEELSKLRQE 530
+N K +K E D + L + L + + KR+ E KL QE
Sbjct: 1020 VNILTKAKTKLEQQVDDLEGSLEQEKKLRMDLER-AKRKLEGDLKLAQE 1067
Score = 31.2 bits (69), Expect = 2.8
Identities = 28/131 (21%), Positives = 61/131 (46%), Gaps = 5/131 (3%)
Query: 311 KQQIRYILQMRGMSDKSLRLVLSTFSNIREELGHLQNDMTSLENDKMRLEKDLSFKDTQL 370
+ ++ ++Q +++ + ++ + + EEL Q+ LE K LE+ + +L
Sbjct: 1741 QSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRL 1800
Query: 371 KEYEEL-LASVRANNHQQQQGLQDSSSKCQALEENNLSLRHTLSDMEYRLKELEYCKRNL 429
E E+L L + + + +++ + + ++ N L E R+KEL Y
Sbjct: 1801 DEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHERRVKELTY---QT 1857
Query: 430 EQENQN-LRMQ 439
E++ +N LR+Q
Sbjct: 1858 EEDRKNVLRLQ 1868
>gi|109659847 filamin A interacting protein 1-like isoform 3 [Homo
sapiens]
Length = 1133
Score = 55.8 bits (133), Expect = 1e-07
Identities = 80/347 (23%), Positives = 151/347 (43%), Gaps = 44/347 (12%)
Query: 267 KNTDLYHCLLEH----LQRIGGSKQDFESTDESE-DIESLIPKGLSEFTKQQIRYILQMR 321
+ +D + CLLE L+++ Q+ +S +E E + E + E TK + ++ +
Sbjct: 187 EKSDEFICLLEQECERLKKL--IDQEIKSQEEKEQEKEKRVTTLKEELTKLKSFALMVVD 244
Query: 322 GMSDKSLRLVLSTFSNIREELGHLQNDMTSL----------ENDKMRLEKDLSFKDTQLK 371
+ +L L I+E + + T L E RLEK+L + T+
Sbjct: 245 EQQRLTAQLTLQR-QKIQELTTNAKETHTKLALAEARVQEEEQKATRLEKELQTQTTKFH 303
Query: 372 EYEELLASVRAN----NHQQQQGLQDSSSKCQALEENNLSLR---HTLSDMEYRLKELEY 424
+ ++ + + N N Q QQ L S + LEE N SLR L D++ ++ + EY
Sbjct: 304 QDQDTIMAKLTNEDSQNRQLQQKLAALSRQIDELEETNRSLRKAEEELQDIKEKISKGEY 363
Query: 425 CKRNLEQENQNLRMQVSETCTGPMLQAKMDEIGNHYTEMVKNLRMEKDREICRLR----- 479
+ E + LR +V + ++ K +E+ E ++L +RE + +
Sbjct: 364 GNAGIMAEVEELRKRVLD------MEGKDEEL-IKMEEQCRDLNKRLERETLQSKDFKLE 416
Query: 480 -SQLNQYHKDVSKREGSCSDFQFKLHELTSLLEEKDSLIKRQSEELSKLRQEIYSSHNQP 538
+L++ + K E + + + + + L LE++ K+ S+EL L+ I
Sbjct: 417 VEKLSKRIMALEKLEDAFNKSKQECYSLKCNLEKERMTTKQLSQELESLKVRIKELEAIE 476
Query: 539 STGGRTTITTKKYRTQYPILGLLYDDYEYIPPGSETQTIVIEKTEDK 585
S +T T K+ T+ L +++ D +T + ++KTEDK
Sbjct: 477 SRLEKTEFTLKEDLTKLKTLTVMFVDER------KTMSEKLKKTEDK 517
>gi|109659845 filamin A interacting protein 1-like isoform 1 [Homo
sapiens]
Length = 1135
Score = 55.8 bits (133), Expect = 1e-07
Identities = 80/347 (23%), Positives = 151/347 (43%), Gaps = 44/347 (12%)
Query: 267 KNTDLYHCLLEH----LQRIGGSKQDFESTDESE-DIESLIPKGLSEFTKQQIRYILQMR 321
+ +D + CLLE L+++ Q+ +S +E E + E + E TK + ++ +
Sbjct: 187 EKSDEFICLLEQECERLKKL--IDQEIKSQEEKEQEKEKRVTTLKEELTKLKSFALMVVD 244
Query: 322 GMSDKSLRLVLSTFSNIREELGHLQNDMTSL----------ENDKMRLEKDLSFKDTQLK 371
+ +L L I+E + + T L E RLEK+L + T+
Sbjct: 245 EQQRLTAQLTLQR-QKIQELTTNAKETHTKLALAEARVQEEEQKATRLEKELQTQTTKFH 303
Query: 372 EYEELLASVRAN----NHQQQQGLQDSSSKCQALEENNLSLR---HTLSDMEYRLKELEY 424
+ ++ + + N N Q QQ L S + LEE N SLR L D++ ++ + EY
Sbjct: 304 QDQDTIMAKLTNEDSQNRQLQQKLAALSRQIDELEETNRSLRKAEEELQDIKEKISKGEY 363
Query: 425 CKRNLEQENQNLRMQVSETCTGPMLQAKMDEIGNHYTEMVKNLRMEKDREICRLR----- 479
+ E + LR +V + ++ K +E+ E ++L +RE + +
Sbjct: 364 GNAGIMAEVEELRKRVLD------MEGKDEEL-IKMEEQCRDLNKRLERETLQSKDFKLE 416
Query: 480 -SQLNQYHKDVSKREGSCSDFQFKLHELTSLLEEKDSLIKRQSEELSKLRQEIYSSHNQP 538
+L++ + K E + + + + + L LE++ K+ S+EL L+ I
Sbjct: 417 VEKLSKRIMALEKLEDAFNKSKQECYSLKCNLEKERMTTKQLSQELESLKVRIKELEAIE 476
Query: 539 STGGRTTITTKKYRTQYPILGLLYDDYEYIPPGSETQTIVIEKTEDK 585
S +T T K+ T+ L +++ D +T + ++KTEDK
Sbjct: 477 SRLEKTEFTLKEDLTKLKTLTVMFVDER------KTMSEKLKKTEDK 517
>gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 55.8 bits (133), Expect = 1e-07
Identities = 64/320 (20%), Positives = 143/320 (44%), Gaps = 40/320 (12%)
Query: 210 SQQIQAITGNNPISTHIGNELCHSGSSQICEQVIIQDDGPEKLDPRYFGELLADLSRKNT 269
+QQI+ + N L H+ S + ++++ E+ + + EL LS+ NT
Sbjct: 1315 TQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESK--AELQRALSKANT 1372
Query: 270 DLYHCLLEHLQRIGGSKQDFESTDESEDIESLIPKGLSEFTKQQIRYILQMRGMSDKSLR 329
++ +K + ++ +E++E K+++ LQ +++ +
Sbjct: 1373 EVAQWR---------TKYETDAIQRTEELEE---------AKKKLAQRLQA---AEEHVE 1411
Query: 330 LVLSTFSNIREELGHLQNDMTSLENDKMRLEKDLSFKDTQLKEYEELLASVRANNHQQQQ 389
V + +++ + LQN++ L D R + D + + ++++LA + +
Sbjct: 1412 AVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEETHA 1471
Query: 390 GLQDSSSKCQALEENNLSLRHTLSDMEYRLKELEYCKRNLEQENQNLRMQVSETCTGPML 449
L+ S + ++L +++ E L +LE KR EN+NL+ ++S+ L
Sbjct: 1472 ELEASQKEARSLGTELFKIKNAY---EESLDQLETLKR----ENKNLQQEISD------L 1518
Query: 450 QAKMDEIGNHYTEMVKNLRMEKDREICRLRSQLNQYHKDVSKREGSCSDFQFKLHELTSL 509
++ E G E+ K ++ + ++E C L++ L + + EG Q +L+++ S
Sbjct: 1519 TEQIAEGGKRIHELEK-IKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKS- 1576
Query: 510 LEEKDSLIKRQSEELSKLRQ 529
E D I + EE+ +L++
Sbjct: 1577 --EVDRKIAEKDEEIDQLKR 1594
Score = 48.5 bits (114), Expect = 2e-05
Identities = 56/223 (25%), Positives = 96/223 (43%), Gaps = 35/223 (15%)
Query: 312 QQIRYILQMRGMSDKSLRLVLSTFSNIREELGHLQNDMTSLENDKMRLEKDLSFKDTQLK 371
+++R L+ S K L S R +L H QN TSL N K +LE D+S
Sbjct: 1692 EELRATLEQTERSRKIAEQELLDASE-RVQLLHTQN--TSLINTKKKLETDIS---QMQG 1745
Query: 372 EYEELLASVRANNHQQQQGLQDSSSKCQA----------LEENNLSLRHTLSDMEYRLKE 421
E E++L R + ++ + D++ + LE ++ T+ D++ RL E
Sbjct: 1746 EMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDE 1805
Query: 422 LE-YCKRNLEQENQNLRMQVSETCTGPMLQAKMDEIGNHYTEMVKNLRMEKDREICRLRS 480
E + +++ Q L +V E L+ +++ E VK LR + +R + L
Sbjct: 1806 AEQLALKGGKKQIQKLEARVRE------LEGEVESEQKRNAEAVKGLR-KHERRVKELTY 1858
Query: 481 QLNQYHKDVSKREGSCSDFQFKLHELTSLLEEKDSLIKRQSEE 523
Q + K++ +L +L L+ K KRQ+EE
Sbjct: 1859 QTEEDRKNI-----------LRLQDLVDKLQAKVKSYKRQAEE 1890
Score = 42.7 bits (99), Expect = 0.001
Identities = 45/205 (21%), Positives = 89/205 (43%), Gaps = 23/205 (11%)
Query: 336 SNIREELGHLQNDMTSLENDKMRLEKDLSFKDTQLKEYEELLASVRANNHQQQQGLQDSS 395
+ ++EE +++++ E + LE+ + T LKE +L V+A + +GL D+
Sbjct: 856 ATMKEEFQKIKDELAKSEAKRKELEEKMV---TLLKEKNDLQLQVQA----EAEGLADAE 908
Query: 396 SKCQALEENNLSLRHTLSDMEYRLK-------ELEYCKRNLEQENQNLRMQVSETCTGPM 448
+C L + + L + ++ R + EL KR LE E L+ + + +
Sbjct: 909 ERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDL---EL 965
Query: 449 LQAKMDEIGNHYTEMVKNLRMEK---DREICRLRSQLNQYHKDVSKREGSCSDFQFKLHE 505
AK+++ + VKNL E D I +L + + + + D Q + +
Sbjct: 966 TLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQE---AHQQTLDDLQAEEDK 1022
Query: 506 LTSLLEEKDSLIKRQSEELSKLRQE 530
+ +L + K L ++ + L QE
Sbjct: 1023 VNTLTKAKIKLEQQVDDLEGSLEQE 1047
Score = 42.7 bits (99), Expect = 0.001
Identities = 50/266 (18%), Positives = 106/266 (39%), Gaps = 29/266 (10%)
Query: 293 DESEDIESLIPKGLSEFTKQQIRYILQMRGMSDKSLRLVLSTFSNIREELGHLQNDMTSL 352
DE E + S + +G FT QQI + + K+ + + R + L+
Sbjct: 1298 DEKEALVSQLSRGKQAFT-QQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEE 1356
Query: 353 ENDKMRLEKDLSFKDTQLKEYEELLASVRANNHQQQQGLQDSSSKC----QALEENNLSL 408
+ K L++ LS +T++ ++ + Q+ + L+++ K QA EE+
Sbjct: 1357 QESKAELQRALSKANTEVAQWR---TKYETDAIQRTEELEEAKKKLAQRLQAAEEH---- 1409
Query: 409 RHTLSDMEYRLKELEYCKRNLEQENQNLRMQVSETCTGPMLQAKMDEIGNHYTEMVKNLR 468
+ + + LE K+ L+ E ++L + V T A +D+ ++
Sbjct: 1410 ---VEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAAC---AALDKKQRNF-------- 1455
Query: 469 MEKDREICRLRSQLNQYHKDVSKREGSCSDFQFKLHELTSLLEEKDSLIKRQSEELSKLR 528
D+ + + + + H ++ + +L ++ + EE ++ E L+
Sbjct: 1456 ---DKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQ 1512
Query: 529 QEIYSSHNQPSTGGRTTITTKKYRTQ 554
QEI Q + GG+ +K + Q
Sbjct: 1513 QEISDLTEQIAEGGKRIHELEKIKKQ 1538
Score = 37.0 bits (84), Expect = 0.051
Identities = 40/196 (20%), Positives = 86/196 (43%), Gaps = 21/196 (10%)
Query: 336 SNIREELGHLQNDMTSLENDKMRLEKDLSFKDTQLKEYEELLASVRANNHQQQQGLQDSS 395
S +++++ L+ + +E +K E + ++ +E +A + Q+ Q +
Sbjct: 954 SELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTL 1013
Query: 396 SKCQALEENNLSLRHTLSDMEYRLKELEYCKRNLEQENQNLRMQVSETCTGPMLQAKMDE 455
QA E+ +L +E ++ +LE +LEQE + LRM + +AK
Sbjct: 1014 DDLQAEEDKVNTLTKAKIKLEQQVDDLE---GSLEQEKK-LRMDLE--------RAKRKL 1061
Query: 456 IGNHYTEMVKNLRMEKDREICRLRSQLNQYHKDVSKREGSCSDFQFKLHELTSLLEEKDS 515
G+ L++ ++ I + ++ Q + + K+E S+ Q K+ + +L +
Sbjct: 1062 EGD--------LKLAQE-SIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQK 1112
Query: 516 LIKRQSEELSKLRQEI 531
IK + +L +EI
Sbjct: 1113 KIKELQARIEELEEEI 1128
Score = 35.0 bits (79), Expect = 0.19
Identities = 57/273 (20%), Positives = 102/273 (37%), Gaps = 67/273 (24%)
Query: 325 DKSLRLVLSTFSNIRE-ELGHLQNDMTSLENDKMRLEKDLSFKDTQLKEYEELLASVRAN 383
+K LR+ L E +L Q + +EN+K +L++ L K+ ++ + + +A
Sbjct: 1047 EKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQAL 1106
Query: 384 NHQQQQGLQDSSSKCQALEEN--------------NLSLRHTLSDMEYRLKE-------- 421
Q Q+ +++ ++ + LEE L L ++ RL+E
Sbjct: 1107 GIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQ 1166
Query: 422 LEYCKRNLEQENQNLRMQVSET-----CTGPMLQAKMDEIGNHYTEMVKNL-----RMEK 471
+E K+ E E Q +R + E T L+ K + E + NL ++EK
Sbjct: 1167 IEMNKKR-EAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEK 1225
Query: 472 DR-----EICRLRSQLNQYHKDVSKREGSCSDFQFKLHELTSL----------------- 509
++ EI L S + K E C + +L EL S
Sbjct: 1226 EKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGR 1285
Query: 510 -----------LEEKDSLIKRQSEELSKLRQEI 531
L+EK++L+ + S Q+I
Sbjct: 1286 LQTESGEFSRQLDEKEALVSQLSRGKQAFTQQI 1318
Score = 29.6 bits (65), Expect = 8.1
Identities = 34/155 (21%), Positives = 67/155 (43%), Gaps = 25/155 (16%)
Query: 393 DSSSKCQALEENNLSLRHTLSDMEYRLKELEYCKRNLEQENQNLRMQV----------SE 442
++ + ++E ++ L+ E + KELE L +E +L++QV E
Sbjct: 850 ETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEE 909
Query: 443 TC-----TGPMLQAKMDEIGNHYTEMVKNLRMEKDREI-CRLRSQLNQYHKDVSKREGSC 496
C T L+AK+ E+ TE R E + EI L ++ + + S+ +
Sbjct: 910 RCDQLIKTKIQLEAKIKEV----TE-----RAEDEEEINAELTAKKRKLEDECSELKKDI 960
Query: 497 SDFQFKLHELTSLLEEKDSLIKRQSEELSKLRQEI 531
D + L ++ ++ +K +EE++ L + I
Sbjct: 961 DDLELTLAKVEKEKHATENKVKNLTEEMAGLDETI 995
>gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 55.8 bits (133), Expect = 1e-07
Identities = 64/320 (20%), Positives = 143/320 (44%), Gaps = 40/320 (12%)
Query: 210 SQQIQAITGNNPISTHIGNELCHSGSSQICEQVIIQDDGPEKLDPRYFGELLADLSRKNT 269
+QQI+ + N L H+ S + ++++ E+ + + EL LS+ NT
Sbjct: 1315 TQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESK--AELQRALSKANT 1372
Query: 270 DLYHCLLEHLQRIGGSKQDFESTDESEDIESLIPKGLSEFTKQQIRYILQMRGMSDKSLR 329
++ +K + ++ +E++E K+++ LQ +++ +
Sbjct: 1373 EVAQWR---------TKYETDAIQRTEELEE---------AKKKLAQRLQA---AEEHVE 1411
Query: 330 LVLSTFSNIREELGHLQNDMTSLENDKMRLEKDLSFKDTQLKEYEELLASVRANNHQQQQ 389
V + +++ + LQN++ L D R + D + + ++++LA + +
Sbjct: 1412 AVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEETHA 1471
Query: 390 GLQDSSSKCQALEENNLSLRHTLSDMEYRLKELEYCKRNLEQENQNLRMQVSETCTGPML 449
L+ S + ++L +++ E L +LE KR EN+NL+ ++S+ L
Sbjct: 1472 ELEASQKEARSLGTELFKIKNAY---EESLDQLETLKR----ENKNLQQEISD------L 1518
Query: 450 QAKMDEIGNHYTEMVKNLRMEKDREICRLRSQLNQYHKDVSKREGSCSDFQFKLHELTSL 509
++ E G E+ K ++ + ++E C L++ L + + EG Q +L+++ S
Sbjct: 1519 TEQIAEGGKRIHELEK-IKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKS- 1576
Query: 510 LEEKDSLIKRQSEELSKLRQ 529
E D I + EE+ +L++
Sbjct: 1577 --EVDRKIAEKDEEIDQLKR 1594
Score = 48.5 bits (114), Expect = 2e-05
Identities = 56/223 (25%), Positives = 96/223 (43%), Gaps = 35/223 (15%)
Query: 312 QQIRYILQMRGMSDKSLRLVLSTFSNIREELGHLQNDMTSLENDKMRLEKDLSFKDTQLK 371
+++R L+ S K L S R +L H QN TSL N K +LE D+S
Sbjct: 1692 EELRATLEQTERSRKIAEQELLDASE-RVQLLHTQN--TSLINTKKKLETDIS---QMQG 1745
Query: 372 EYEELLASVRANNHQQQQGLQDSSSKCQA----------LEENNLSLRHTLSDMEYRLKE 421
E E++L R + ++ + D++ + LE ++ T+ D++ RL E
Sbjct: 1746 EMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDE 1805
Query: 422 LE-YCKRNLEQENQNLRMQVSETCTGPMLQAKMDEIGNHYTEMVKNLRMEKDREICRLRS 480
E + +++ Q L +V E L+ +++ E VK LR + +R + L
Sbjct: 1806 AEQLALKGGKKQIQKLEARVRE------LEGEVESEQKRNAEAVKGLR-KHERRVKELTY 1858
Query: 481 QLNQYHKDVSKREGSCSDFQFKLHELTSLLEEKDSLIKRQSEE 523
Q + K++ +L +L L+ K KRQ+EE
Sbjct: 1859 QTEEDRKNI-----------LRLQDLVDKLQAKVKSYKRQAEE 1890
Score = 42.7 bits (99), Expect = 0.001
Identities = 45/205 (21%), Positives = 89/205 (43%), Gaps = 23/205 (11%)
Query: 336 SNIREELGHLQNDMTSLENDKMRLEKDLSFKDTQLKEYEELLASVRANNHQQQQGLQDSS 395
+ ++EE +++++ E + LE+ + T LKE +L V+A + +GL D+
Sbjct: 856 ATMKEEFQKIKDELAKSEAKRKELEEKMV---TLLKEKNDLQLQVQA----EAEGLADAE 908
Query: 396 SKCQALEENNLSLRHTLSDMEYRLK-------ELEYCKRNLEQENQNLRMQVSETCTGPM 448
+C L + + L + ++ R + EL KR LE E L+ + + +
Sbjct: 909 ERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDL---EL 965
Query: 449 LQAKMDEIGNHYTEMVKNLRMEK---DREICRLRSQLNQYHKDVSKREGSCSDFQFKLHE 505
AK+++ + VKNL E D I +L + + + + D Q + +
Sbjct: 966 TLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQE---AHQQTLDDLQAEEDK 1022
Query: 506 LTSLLEEKDSLIKRQSEELSKLRQE 530
+ +L + K L ++ + L QE
Sbjct: 1023 VNTLTKAKIKLEQQVDDLEGSLEQE 1047
Score = 42.7 bits (99), Expect = 0.001
Identities = 50/266 (18%), Positives = 106/266 (39%), Gaps = 29/266 (10%)
Query: 293 DESEDIESLIPKGLSEFTKQQIRYILQMRGMSDKSLRLVLSTFSNIREELGHLQNDMTSL 352
DE E + S + +G FT QQI + + K+ + + R + L+
Sbjct: 1298 DEKEALVSQLSRGKQAFT-QQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEE 1356
Query: 353 ENDKMRLEKDLSFKDTQLKEYEELLASVRANNHQQQQGLQDSSSKC----QALEENNLSL 408
+ K L++ LS +T++ ++ + Q+ + L+++ K QA EE+
Sbjct: 1357 QESKAELQRALSKANTEVAQWR---TKYETDAIQRTEELEEAKKKLAQRLQAAEEH---- 1409
Query: 409 RHTLSDMEYRLKELEYCKRNLEQENQNLRMQVSETCTGPMLQAKMDEIGNHYTEMVKNLR 468
+ + + LE K+ L+ E ++L + V T A +D+ ++
Sbjct: 1410 ---VEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAAC---AALDKKQRNF-------- 1455
Query: 469 MEKDREICRLRSQLNQYHKDVSKREGSCSDFQFKLHELTSLLEEKDSLIKRQSEELSKLR 528
D+ + + + + H ++ + +L ++ + EE ++ E L+
Sbjct: 1456 ---DKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQ 1512
Query: 529 QEIYSSHNQPSTGGRTTITTKKYRTQ 554
QEI Q + GG+ +K + Q
Sbjct: 1513 QEISDLTEQIAEGGKRIHELEKIKKQ 1538
Score = 37.0 bits (84), Expect = 0.051
Identities = 40/196 (20%), Positives = 86/196 (43%), Gaps = 21/196 (10%)
Query: 336 SNIREELGHLQNDMTSLENDKMRLEKDLSFKDTQLKEYEELLASVRANNHQQQQGLQDSS 395
S +++++ L+ + +E +K E + ++ +E +A + Q+ Q +
Sbjct: 954 SELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTL 1013
Query: 396 SKCQALEENNLSLRHTLSDMEYRLKELEYCKRNLEQENQNLRMQVSETCTGPMLQAKMDE 455
QA E+ +L +E ++ +LE +LEQE + LRM + +AK
Sbjct: 1014 DDLQAEEDKVNTLTKAKIKLEQQVDDLE---GSLEQEKK-LRMDLE--------RAKRKL 1061
Query: 456 IGNHYTEMVKNLRMEKDREICRLRSQLNQYHKDVSKREGSCSDFQFKLHELTSLLEEKDS 515
G+ L++ ++ I + ++ Q + + K+E S+ Q K+ + +L +
Sbjct: 1062 EGD--------LKLAQE-SIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQK 1112
Query: 516 LIKRQSEELSKLRQEI 531
IK + +L +EI
Sbjct: 1113 KIKELQARIEELEEEI 1128
Score = 35.0 bits (79), Expect = 0.19
Identities = 57/273 (20%), Positives = 102/273 (37%), Gaps = 67/273 (24%)
Query: 325 DKSLRLVLSTFSNIRE-ELGHLQNDMTSLENDKMRLEKDLSFKDTQLKEYEELLASVRAN 383
+K LR+ L E +L Q + +EN+K +L++ L K+ ++ + + +A
Sbjct: 1047 EKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQAL 1106
Query: 384 NHQQQQGLQDSSSKCQALEEN--------------NLSLRHTLSDMEYRLKE-------- 421
Q Q+ +++ ++ + LEE L L ++ RL+E
Sbjct: 1107 GIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQ 1166
Query: 422 LEYCKRNLEQENQNLRMQVSET-----CTGPMLQAKMDEIGNHYTEMVKNL-----RMEK 471
+E K+ E E Q +R + E T L+ K + E + NL ++EK
Sbjct: 1167 IEMNKKR-EAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEK 1225
Query: 472 DR-----EICRLRSQLNQYHKDVSKREGSCSDFQFKLHELTSL----------------- 509
++ EI L S + K E C + +L EL S
Sbjct: 1226 EKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGR 1285
Query: 510 -----------LEEKDSLIKRQSEELSKLRQEI 531
L+EK++L+ + S Q+I
Sbjct: 1286 LQTESGEFSRQLDEKEALVSQLSRGKQAFTQQI 1318
Score = 29.6 bits (65), Expect = 8.1
Identities = 34/155 (21%), Positives = 67/155 (43%), Gaps = 25/155 (16%)
Query: 393 DSSSKCQALEENNLSLRHTLSDMEYRLKELEYCKRNLEQENQNLRMQV----------SE 442
++ + ++E ++ L+ E + KELE L +E +L++QV E
Sbjct: 850 ETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEE 909
Query: 443 TC-----TGPMLQAKMDEIGNHYTEMVKNLRMEKDREI-CRLRSQLNQYHKDVSKREGSC 496
C T L+AK+ E+ TE R E + EI L ++ + + S+ +
Sbjct: 910 RCDQLIKTKIQLEAKIKEV----TE-----RAEDEEEINAELTAKKRKLEDECSELKKDI 960
Query: 497 SDFQFKLHELTSLLEEKDSLIKRQSEELSKLRQEI 531
D + L ++ ++ +K +EE++ L + I
Sbjct: 961 DDLELTLAKVEKEKHATENKVKNLTEEMAGLDETI 995
>gi|109659849 filamin A interacting protein 1-like isoform 2 [Homo
sapiens]
Length = 893
Score = 55.5 bits (132), Expect = 1e-07
Identities = 60/246 (24%), Positives = 111/246 (45%), Gaps = 26/246 (10%)
Query: 353 ENDKMRLEKDLSFKDTQLKEYEELLASVRAN----NHQQQQGLQDSSSKCQALEENNLSL 408
E RLEK+L + T+ + ++ + + N N Q QQ L S + LEE N SL
Sbjct: 45 EQKATRLEKELQTQTTKFHQDQDTIMAKLTNEDSQNRQLQQKLAALSRQIDELEETNRSL 104
Query: 409 R---HTLSDMEYRLKELEYCKRNLEQENQNLRMQVSETCTGPMLQAKMDEIGNHYTEMVK 465
R L D++ ++ + EY + E + LR +V + ++ K +E+ E +
Sbjct: 105 RKAEEELQDIKEKISKGEYGNAGIMAEVEELRKRVLD------MEGKDEEL-IKMEEQCR 157
Query: 466 NLRMEKDREICRLR------SQLNQYHKDVSKREGSCSDFQFKLHELTSLLEEKDSLIKR 519
+L +RE + + +L++ + K E + + + + + L LE++ K+
Sbjct: 158 DLNKRLERETLQSKDFKLEVEKLSKRIMALEKLEDAFNKSKQECYSLKCNLEKERMTTKQ 217
Query: 520 QSEELSKLRQEIYSSHNQPSTGGRTTITTKKYRTQYPILGLLYDDYEYIPPGSETQTIVI 579
S+EL L+ I S +T T K+ T+ L +++ D +T + +
Sbjct: 218 LSQELESLKVRIKELEAIESRLEKTEFTLKEDLTKLKTLTVMFVDER------KTMSEKL 271
Query: 580 EKTEDK 585
+KTEDK
Sbjct: 272 KKTEDK 277
>gi|55770834 centromere protein F [Homo sapiens]
Length = 3114
Score = 55.5 bits (132), Expect = 1e-07
Identities = 48/207 (23%), Positives = 96/207 (46%), Gaps = 15/207 (7%)
Query: 340 EELGHLQNDMTSLENDKMRLEKDLSFKDTQLKEYEELLASVRANNHQQQQGLQDSSSKCQ 399
+E LQ ++ + +K+ + K L + E+ L+S + HQ ++G++ + +
Sbjct: 2070 KESESLQARLSESDYEKLNVSKALEAALVEKGEFALRLSSTQEEVHQLRRGIEKLRVRIE 2129
Query: 400 ALEENNLSLRHTLSDMEYRLKELEYCKRNLE------QENQNLRMQVSETCTGPMLQAKM 453
A E+ L + L + E L+ NLE +ENQ L + +E +A++
Sbjct: 2130 ADEKKQLHIAEKLKERERENDSLKDKVENLERELQMSEENQELVILDAENS-----KAEV 2184
Query: 454 DEIGNHYTEMVKNLRMEKDREICRLRSQLNQYHKDVSKREGSCSDFQFKLHELTSLLEEK 513
+ + EM ++L++ + ++ LRS+ K + +++G S+ L SLLEEK
Sbjct: 2185 ETLKTQIEEMARSLKVF-ELDLVTLRSEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEK 2243
Query: 514 DSL---IKRQSEELSKLRQEIYSSHNQ 537
+ IK +S+ ++ Q N+
Sbjct: 2244 EQAEIQIKEESKTAVEMLQNQLKELNE 2270
Score = 45.4 bits (106), Expect = 1e-04
Identities = 82/450 (18%), Positives = 176/450 (39%), Gaps = 48/450 (10%)
Query: 115 QNTEQELHSPTVKLTTYPQTTIRKYVVQNPEQEPLSQF---LRGSHFFPGNNVI-----Y 166
+ EQEL +L Q V NP P F L S ++ G+ Y
Sbjct: 112 EKLEQELKRCKSELERSQQAAQSADVSLNPCNTPQKIFTTPLTPSQYYSGSKYEDLKEKY 171
Query: 167 EKTIRKVEKLNTD---------QGCHPQAQCHHHIIQQPQVIHSAH-WQQPDSSQQIQAI 216
K + + ++L + PQA +H I + Q S WQQ + + +
Sbjct: 172 NKEVEERKRLEAEVKALQAKKASQTLPQATMNHRDIARHQASSSVFSWQQEKTPSHLSSN 231
Query: 217 TGNNPISTHIGNELCHSGSSQICEQVIIQDDGPEKLDPRYFGE-----LLADLSRKNTDL 271
+ PI SG ++ G + +F LL L +N +L
Sbjct: 232 SQRTPIRRDFSASY-FSGEQEVTPSRSTLQIGKRDANSSFFDNSSSPHLLDQLKAQNQEL 290
Query: 272 YHCLLEHLQRIGGSKQDFES-TDESEDIESLIPKGLSEFTKQQIRYILQMRGMSDKSLRL 330
+ + E R+ G +++ + ++ ++++ + K E +++ + D+ +R
Sbjct: 291 RNKINELELRLQGHEKEMKGQVNKFQELQLQLEKAKVELIEKE----KVLNKCRDELVRT 346
Query: 331 VL------STFSNIREELGHLQNDMT----SLENDKMRLEKDLSFKDTQLKEYEELLASV 380
+ ++ + ++L L D++ + E+ + LE+ + K+ + +E EL
Sbjct: 347 TAQYDQASTKYTALEQKLKKLTEDLSCQRQNAESARCSLEQKIKEKEKEFQE--ELSRQQ 404
Query: 381 RANNHQQQQGLQDSSSKCQALEENNLSLRHTLSDMEYRLKELEYCKRNLEQENQNL---- 436
R+ Q+ +Q + Q L++ ++++ + + NLE+ Q L
Sbjct: 405 RSFQTLDQECIQMKARLTQELQQAKNMHNVLQAELDKLTSVKQQLENNLEEFKQKLCRAE 464
Query: 437 -RMQVSETCTGPMLQAKMDEIGNHYTEMVKNLRMEKDREICRLRSQLNQYHKDVSKREGS 495
Q S+ L+ M+E+ ++K+ +K RE+C L ++L + +++ +
Sbjct: 465 QAFQASQIKENE-LRRSMEEMKKE-NNLLKSHSEQKAREVCHLEAELKNIKQCLNQSQNF 522
Query: 496 CSDFQFKLHELTSLLEEKDSLIKRQSEELS 525
+ + K ++L + I +Q L+
Sbjct: 523 AEEMKAKNTSQETMLRDLQEKINQQENSLT 552
Score = 45.1 bits (105), Expect = 2e-04
Identities = 51/218 (23%), Positives = 95/218 (43%), Gaps = 27/218 (12%)
Query: 340 EELGHLQNDMTSLENDKMRLEKDLSFKDTQLKEYEELLASVR-ANNHQQQQGLQDSSSKC 398
+ L L+ D+ ++ ++K L +L + ++ E E + +S ++Q+ +Q
Sbjct: 2378 QSLRGLELDVVTIRSEKENLTNELQKEQERISELEIINSSFENILQEKEQEKVQMKEKSS 2437
Query: 399 QALEENNLSLRHTLSDMEYRLKELEYCKRNLEQENQNLRMQVS--ETCTGPMLQAKMDEI 456
A+E L+ L ++ R+ L + + + QNL QV E +LQ +DE
Sbjct: 2438 TAME----MLQTQLKELNERVAALHNDQEACKAKEQNLSSQVECLELEKAQLLQG-LDEA 2492
Query: 457 GNHY-------------TEMVKNLRMEKDREICRLRSQLNQYHKDVSKREGSCSDFQ--- 500
N+Y E K +KD EI RL++Q+ + VSK + Q
Sbjct: 2493 KNNYIVLQSSVNGLIQEVEDGKQKLEKKDEEISRLKNQIQDQEQLVSKLSQVEGEHQLWK 2552
Query: 501 ---FKLHELTSLLEEKDSLIKRQSEELSKLRQEIYSSH 535
+L LT LE+K +++ ++ L + + SS+
Sbjct: 2553 EQNLELRNLTVELEQKIQVLQSKNASLQDTLEVLQSSY 2590
Score = 42.4 bits (98), Expect = 0.001
Identities = 54/275 (19%), Positives = 114/275 (41%), Gaps = 36/275 (13%)
Query: 286 KQDFESTDESEDIESLIPKGLSEFTKQQIRYILQMRGMSDKSLRLVLSTFSNIREELGHL 345
+++ E E E I S L E ++++ QM+ S ++ ++ + + E + L
Sbjct: 2402 QKEQERISELEIINSSFENILQEKEQEKV----QMKEKSSTAMEMLQTQLKELNERVAAL 2457
Query: 346 QNDMTSLENDKMRLEKDLSFKDTQLKEYEELLASVRANNHQQQ-------QGLQDSSSKC 398
ND + + + L + + + + + L + N Q Q ++D K
Sbjct: 2458 HNDQEACKAKEQNLSSQVECLELEKAQLLQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKL 2517
Query: 399 QALEENNLSLRHTLSDMEYRLKELE--------YCKRNLEQENQNL----RMQVSETCTG 446
+ +E L++ + D E + +L + ++NLE N + ++QV ++
Sbjct: 2518 EKKDEEISRLKNQIQDQEQLVSKLSQVEGEHQLWKEQNLELRNLTVELEQKIQVLQS-KN 2576
Query: 447 PMLQAKMDEIGNHYTEMVKNLRMEKDREICRLRSQLNQYHKDVSKREGSCSDFQFKLHEL 506
LQ ++ + + Y + L + K ++ + + V+K ++ Q ++HE+
Sbjct: 2577 ASLQDTLEVLQSSYKNLENELELTKMDKM--------SFVEKVNKMTAKETELQREMHEM 2628
Query: 507 ----TSLLEEKDSLIKRQSEELSKLRQEIYSSHNQ 537
L EE R + EL L +EI SS +Q
Sbjct: 2629 AQKTAELQEELSGEKNRLAGELQLLLEEIKSSKDQ 2663
Score = 41.2 bits (95), Expect = 0.003
Identities = 59/285 (20%), Positives = 120/285 (42%), Gaps = 23/285 (8%)
Query: 260 LLADLSRKNTDLYHCLLEHLQRIGGSKQDFESTDESEDIESLIPKGLSEFTKQQIRYILQ 319
L AD S KN+ + ++ L+ S++ S + + E + KG E +++
Sbjct: 816 LEADQSPKNSAILQNRVDSLEFSLESQKQMNSDLQKQCEELVQIKGEIE------ENLMK 869
Query: 320 MRGMSDKSLRLVLSTFSNIREELGHLQNDMTSLENDKMRLEKDLSFKDTQLKEYEELLAS 379
M + S ++E+ QN + + EK+L + +++ + +
Sbjct: 870 AEQMHQSFVAETSQRISKLQEDTSAHQNVVAETLSALENKEKELQLLNDKVETEQAEIQE 929
Query: 380 VRANNHQQQQGLQDSS--SKCQALEENNLSL-----RHTLSDMEYRLKELEYCKRNLEQE 432
++ +NH + L++ S+ +LE+ +S + + ++ L+ +L QE
Sbjct: 930 LKKSNHLLEDSLKELQLLSETLSLEKKEMSSIISLNKREIEELTQENGTLKEINASLNQE 989
Query: 433 NQNLRMQVSETCTGPMLQAKMDEIGNHYTEMVKNLRMEKDREICRLRSQLNQYHKDVSKR 492
NL +Q SE+ +DE +E+ + EK + R N Y +D+S++
Sbjct: 990 KMNL-IQKSESFAN-----YIDEREKSISELSDQYKQEKLILLQRCEETGNAY-EDLSQK 1042
Query: 493 EGSCSDFQFKLHELTSLLEEKDSLIKRQSEELSKLRQEIYSSHNQ 537
+ Q K +L LL E SL + + EL +L++ H +
Sbjct: 1043 YKAA---QEKNSKLECLLNECTSLCENRKNELEQLKEAFAKEHQE 1084
Score = 40.0 bits (92), Expect = 0.006
Identities = 58/285 (20%), Positives = 113/285 (39%), Gaps = 42/285 (14%)
Query: 288 DFESTDESEDIESLIPKGLSEFTKQQIRYILQMRGMSDKSLRLVLSTFSNIREEL----G 343
D T+++E E L E + ++++ + + + K + ++S EEL G
Sbjct: 918 DKVETEQAEIQELKKSNHLLEDSLKELQLLSETLSLEKKEMSSIISLNKREIEELTQENG 977
Query: 344 HLQNDMTSLENDKMRL--------------EKDLSFKDTQLKEYEELLASVRANNHQQQQ 389
L+ SL +KM L EK +S Q K+ E+L+ R +
Sbjct: 978 TLKEINASLNQEKMNLIQKSESFANYIDEREKSISELSDQYKQ-EKLILLQRCE--ETGN 1034
Query: 390 GLQDSSSKCQALEENNLSLRHTLSDM----EYRLKELEYCKRNLEQENQNLRMQVSETCT 445
+D S K +A +E N L L++ E R ELE K +E+Q +++
Sbjct: 1035 AYEDLSQKYKAAQEKNSKLECLLNECTSLCENRKNELEQLKEAFAKEHQEFLTKLAFA-- 1092
Query: 446 GPMLQAKMDEIGNHYTEMVKNLRMEKDREICRLRSQLNQYHKDVSKREGSCSDFQFKLHE 505
E +NL +E + LRS++ + G L E
Sbjct: 1093 ---------------EERNQNLMLELETVQQALRSEMTDNQNNSKSEAGGLKQEIMTLKE 1137
Query: 506 LTSLLEEKDSLIKRQSEELSKLRQEIYSSHNQPSTGGRTTITTKK 550
+ ++++ + + +++E+L K+ + + N S R ++ ++
Sbjct: 1138 EQNKMQKEVNDLLQENEQLMKVMKTKHECQNLESEPIRNSVKERE 1182
Score = 38.5 bits (88), Expect = 0.017
Identities = 43/227 (18%), Positives = 104/227 (45%), Gaps = 27/227 (11%)
Query: 325 DKSLRLVLSTFSNIREELGHLQNDMTSLE--NDKMRLEKD------------LSFKDTQL 370
++ L +V S + +R EL + T+L+ ++KM+ + + + ++
Sbjct: 1950 EEELSVVTSERNQLRGELDTMSKKTTALDQLSEKMKEKTQELESHQSECLHCIQVAEAEV 2009
Query: 371 KEYEELLASVRANNHQQQQGLQDSSSKCQALEENNLSLRHTLSDMEYRLKELEYCKRNLE 430
KE ELL ++ ++ + + K Q+LE+++ +L T ++E ++ +L K L
Sbjct: 2010 KEKTELLQTLSSDVSELLKDKTHLQEKLQSLEKDSQALSLTKCELENQIAQLNKEKELLV 2069
Query: 431 QENQNLRMQVSETCTGPMLQAKMDEIGNHYTEMVKNLRMEKDREICRLRS---QLNQYHK 487
+E+++L+ ++SE+ D + ++ ++ +EK RL S +++Q +
Sbjct: 2070 KESESLQARLSES----------DYEKLNVSKALEAALVEKGEFALRLSSTQEEVHQLRR 2119
Query: 488 DVSKREGSCSDFQFKLHELTSLLEEKDSLIKRQSEELSKLRQEIYSS 534
+ K + K + L+E++ +++ L +E+ S
Sbjct: 2120 GIEKLRVRIEADEKKQLHIAEKLKERERENDSLKDKVENLERELQMS 2166
Score = 37.4 bits (85), Expect = 0.039
Identities = 57/233 (24%), Positives = 97/233 (41%), Gaps = 27/233 (11%)
Query: 259 ELLADLSRKNTDLYHCLLEHLQRIGGSKQDF-ESTDESEDIESLIPKGLSEFTKQQIR-- 315
EL +LS + L L L+ I SK E T E+ +++ K L K Q+
Sbjct: 2634 ELQEELSGEKNRLAGELQLLLEEIKSSKDQLKELTLENSELK----KSLDCMHKDQVEKE 2689
Query: 316 ---------YILQMRGMSDKSLRLVLSTFSNIREELGHLQNDMTSLEN--DKMRLEKDLS 364
Y L++ K L+L T E+ + +TS E +LE DL
Sbjct: 2690 GKVREEIAEYQLRLHEAEKKHQALLLDTNKQYEVEIQTYREKLTSKEECLSSQKLEIDL- 2748
Query: 365 FKDTQLKEYEELLASVRANNH---QQQQGLQDSSSKCQALEENNLSLRHTLSDMEYRLKE 421
K ++ EEL S++A + ++ D+ L++ N + + + K+
Sbjct: 2749 LKSSK----EELNNSLKATTQILEELKKTKMDNLKYVNQLKKENERAQGKMKLLIKSCKQ 2804
Query: 422 LEYCKRNLEQENQNLRMQVSETCTGPMLQAKMDEIGNHYTEMVKNLRMEKDRE 474
LE K L++E L+ + TG ++ K+DE+ E+ + L EK +E
Sbjct: 2805 LEEEKEILQKELSQLQAAQEKQKTGTVMDTKVDELTTEIKELKETLE-EKTKE 2856
Score = 35.0 bits (79), Expect = 0.19
Identities = 43/208 (20%), Positives = 86/208 (41%), Gaps = 12/208 (5%)
Query: 330 LVLSTFSNIREELGHLQNDMTSLENDKMRLEKDLSFKDTQLKEYEELLASVRANNHQQQQ 389
LV F +E++ +LQ + N+ +RL + +D +++ + + + H Q+
Sbjct: 1757 LVPMDFLGNQEDIHNLQLRVKETSNENLRLLHVIEDRDRKVESLLNEMKELDSKLHLQEV 1816
Query: 390 GLQDSSSKCQALEENNLSLRHTLSDMEYRLKELEYCKRNLEQENQNLRMQVSETCTGPML 449
L C LE+ L+ SD+ +L+ + L Q R++ SE +
Sbjct: 1817 QLMTKIEACIELEKIVGELKKENSDLSEKLEYFSCDHQELLQ-----RVETSEGLNSDLE 1871
Query: 450 ----QAKMDEIGNHYTEM---VKNLRMEKDREICRLRSQLNQYHKDVSKREGSCSDFQFK 502
++ ++IG++ ++ K ++ + E+ R+RS+ + E Q +
Sbjct: 1872 MHADKSSREDIGDNVAKVNDSWKERFLDVENELSRIRSEKASIEHEALYLEADLEVVQTE 1931
Query: 503 LHELTSLLEEKDSLIKRQSEELSKLRQE 530
L E K +I EELS + E
Sbjct: 1932 KLCLEKDNENKQKVIVCLEEELSVVTSE 1959
Score = 33.1 bits (74), Expect = 0.73
Identities = 44/252 (17%), Positives = 96/252 (38%), Gaps = 47/252 (18%)
Query: 340 EELGHLQNDMTSLENDKMRLEKDLSFKDTQLKEYEELLASVRANNHQQQQGLQDSSSKCQ 399
+++ L+ + L+ +K + + L + L++ ++ + + + ++ Q C+
Sbjct: 18 QKIQELEGQLDKLKKEKQQRQFQLDSLEAALQKQKQKVENEKTEGTNLKRENQRLMEICE 77
Query: 400 ALEENNLSLRHTLSDMEYRL------------------KELEYCKRNLEQENQ------- 434
+LE+ + H L E ++ +EL+ CK LE+ Q
Sbjct: 78 SLEKTKQKISHELQVKESQVNFQEGQLNSGKKQIEKLEQELKRCKSELERSQQAAQSADV 137
Query: 435 -----NLRMQVSETCTGPMLQ---AKMDEIGNHYTEMVKNLRMEKDREICRLRS------ 480
N ++ T P +K +++ Y + V+ R + E+ L++
Sbjct: 138 SLNPCNTPQKIFTTPLTPSQYYSGSKYEDLKEKYNKEVEE-RKRLEAEVKALQAKKASQT 196
Query: 481 --QLNQYHKDVSKREGSCSDFQFKLHELTSLLEEKDSLIKRQSEELSKLRQEIYSSHNQP 538
Q H+D+++ + S S F ++ + S L Q + + Y S Q
Sbjct: 197 LPQATMNHRDIARHQASSSVFSWQQEKTPSHLSSNS-----QRTPIRRDFSASYFSGEQE 251
Query: 539 STGGRTTITTKK 550
T R+T+ K
Sbjct: 252 VTPSRSTLQIGK 263
>gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo
sapiens]
Length = 1939
Score = 55.1 bits (131), Expect = 2e-07
Identities = 63/320 (19%), Positives = 140/320 (43%), Gaps = 40/320 (12%)
Query: 210 SQQIQAITGNNPISTHIGNELCHSGSSQICEQVIIQDDGPEKLDPRYFGELLADLSRKNT 269
+QQI+ + T + L H+ S + ++++ E+ + + EL +S+ N+
Sbjct: 1313 TQQIEELKRQLEEETKAKSTLAHALQSARHDCDLLREQYEEEQEAK--AELQRGMSKANS 1370
Query: 270 DLYHCLLEHLQRIGGSKQDFESTDESEDIESLIPKGLSEFTKQQIRYILQMRGMSDKSLR 329
++ ++ + T+E E+ + + + L + +++ +
Sbjct: 1371 EVAQWRTKY------ETDAIQRTEELEEAKKKLAQRLQD---------------AEEHVE 1409
Query: 330 LVLSTFSNIREELGHLQNDMTSLENDKMRLEKDLSFKDTQLKEYEELLASVRANNHQQQQ 389
V S +++ + LQN++ L D R D + + ++++LA + + Q
Sbjct: 1410 AVNSKCASLEKTKQRLQNEVEDLMIDVERSNAACIALDKKQRNFDKVLAEWKQKYEETQA 1469
Query: 390 GLQDSSSKCQALEENNLSLRHTLSDMEYRLKELEYCKRNLEQENQNLRMQVSETCTGPML 449
L+ S + ++L +++ E L LE KR EN+NL+ ++S+ L
Sbjct: 1470 ELEASQKESRSLSTELFKVKNAY---EESLDHLETLKR----ENKNLQQEISD------L 1516
Query: 450 QAKMDEIGNHYTEMVKNLRMEKDREICRLRSQLNQYHKDVSKREGSCSDFQFKLHELTSL 509
++ E G H E+ K ++ + D E L++ L + + EG Q +L+++ S
Sbjct: 1517 TEQIAEGGKHIHELEK-VKKQLDHEKSELQTSLEEAEASLEHEEGKILRIQLELNQVKSE 1575
Query: 510 LEEKDSLIKRQSEELSKLRQ 529
++ K I + EEL +L++
Sbjct: 1576 IDRK---IAEKDEELDQLKR 1592
Score = 47.4 bits (111), Expect = 4e-05
Identities = 49/202 (24%), Positives = 90/202 (44%), Gaps = 46/202 (22%)
Query: 339 REELGHLQNDMTSLENDKMRLEKDLSFKDTQLK-EYEELLASVRANNHQQQQGLQDSSSK 397
R +L H QN TSL N K +LE D+S Q++ E E+++ R + ++ + D++
Sbjct: 1716 RVQLLHTQN--TSLINTKKKLETDIS----QIQGEMEDIVQEARNAEEKAKKAITDAAMM 1769
Query: 398 CQALEENNLSLRHTLSDMEYRLKELEYCKRNLEQENQNLRMQVSET-------------- 443
+ L++ + H LE K+N+EQ ++L++++ E
Sbjct: 1770 AEELKKEQDTSAH-----------LERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQK 1818
Query: 444 --CTGPMLQAKMDEIGNHYTEMVKNLRMEKDREICRLRSQLNQYHKDVSKREGSCSDFQF 501
L+++++ H E VK LR + +R + L Q + K++
Sbjct: 1819 LEARVRELESEVESEQKHNVEAVKGLR-KHERRVKELTYQTEEDRKNI-----------L 1866
Query: 502 KLHELTSLLEEKDSLIKRQSEE 523
+L +L L+ K KRQ+EE
Sbjct: 1867 RLQDLVDKLQTKVKAYKRQAEE 1888
Score = 38.5 bits (88), Expect = 0.017
Identities = 58/297 (19%), Positives = 113/297 (38%), Gaps = 42/297 (14%)
Query: 277 EHLQRIGGSKQDFESTDESEDIESLIPKGLS------EFTKQQIRYILQMRGMSDKSLRL 330
E R KQ + + E E+I + + E K++ +MR ++S
Sbjct: 1129 ERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEESTLQ 1188
Query: 331 VLSTFSNIREE----LGHLQNDMTSLENDKMRLEKD---LSFKDTQLKEYEELLASVRAN 383
+T + +R++ + L + SL+ K +LEK+ L + L E ++ +AN
Sbjct: 1189 HEATAAALRKKHADSVAELGEQIDSLQRVKQKLEKEKSELKMEINDLASNMETVSKAKAN 1248
Query: 384 NHQQQQGLQDSSSKCQALEENNLSLRHTLSDMEYRL------------------KELEYC 425
+ + L+D S+ + EE L + LS + RL +L
Sbjct: 1249 FEKMCRTLEDQLSEIKTKEEEQQRLINELSAQKARLHTESGEFSRQLDEKDAMVSQLSRG 1308
Query: 426 KRNLEQENQNLRMQVSETCTGPMLQAKMDEIGNHYTEMVK-------NLRMEKDREICRL 478
K+ Q+ + L+ Q+ E A + H ++++ + E R + +
Sbjct: 1309 KQAFTQQIEELKRQLEEETKAKSTLAHALQSARHDCDLLREQYEEEQEAKAELQRGMSKA 1368
Query: 479 RSQLNQ----YHKDVSKREGSCSDFQFKLHELTSLLEEKDSLIKRQSEELSKLRQEI 531
S++ Q Y D +R + + KL + EE + + L K +Q +
Sbjct: 1369 NSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNSKCASLEKTKQRL 1425
Score = 37.4 bits (85), Expect = 0.039
Identities = 45/262 (17%), Positives = 100/262 (38%), Gaps = 21/262 (8%)
Query: 293 DESEDIESLIPKGLSEFTKQQIRYILQMRGMSDKSLRLVLSTFSNIREELGHLQNDMTSL 352
DE + + S + +G FT QQI + + K+ + + R + L+
Sbjct: 1296 DEKDAMVSQLSRGKQAFT-QQIEELKRQLEEETKAKSTLAHALQSARHDCDLLREQYEEE 1354
Query: 353 ENDKMRLEKDLSFKDTQLKEYEELLASVRANNHQQQQGLQDSSSKCQALEENNLSLRHTL 412
+ K L++ +S ++++ ++ + D+ + + LEE L L
Sbjct: 1355 QEAKAELQRGMSKANSEVAQWRTKYET-------------DAIQRTEELEEAKKKLAQRL 1401
Query: 413 SDMEYRLKELEYCKRNLEQENQNLRMQVSETCTGPMLQAKMDEIGNHYTEMVKNLRMEKD 472
D E ++ + +LE+ Q L+ +V + M+ E N + + D
Sbjct: 1402 QDAEEHVEAVNSKCASLEKTKQRLQNEVEDL----MIDV---ERSNAACIALDKKQRNFD 1454
Query: 473 REICRLRSQLNQYHKDVSKREGSCSDFQFKLHELTSLLEEKDSLIKRQSEELSKLRQEIY 532
+ + + + + ++ + +L ++ + EE ++ E L+QEI
Sbjct: 1455 KVLAEWKQKYEETQAELEASQKESRSLSTELFKVKNAYEESLDHLETLKRENKNLQQEIS 1514
Query: 533 SSHNQPSTGGRTTITTKKYRTQ 554
Q + GG+ +K + Q
Sbjct: 1515 DLTEQIAEGGKHIHELEKVKKQ 1536
Score = 37.0 bits (84), Expect = 0.051
Identities = 38/196 (19%), Positives = 82/196 (41%), Gaps = 18/196 (9%)
Query: 338 IREELGHLQNDMTSLENDKMRLEKDLSFKDTQLKEYEELLASVRANNHQQQQGLQDSSSK 397
+ +E L+ D+ LE ++EK+ + ++K E +A + + + + +
Sbjct: 947 LEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGL-------DETIAKLTKE 999
Query: 398 CQALEENNLSLRHTLSDMEYRLKELEYCKRNLEQENQNLR--MQVSETCTGPMLQAKMDE 455
+AL+E + L E ++ L K LEQ+ +L ++ + + +AK
Sbjct: 1000 KKALQEAHQQTLDDLQMEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLCMDLERAKRKL 1059
Query: 456 IGNHYTEMVKNLRMEKDREICRLRSQLNQYHKDVSKREGSCSDFQFKLHELTSLLEEKDS 515
G+ + E D++ Q ++ + K+E S+ Q K+ + +L +
Sbjct: 1060 EGDLKLAQESTMDTENDKQ---------QLNEKLKKKEFEMSNLQGKIEDEQALAIQLQK 1110
Query: 516 LIKRQSEELSKLRQEI 531
IK + +L +EI
Sbjct: 1111 KIKELQARIEELEEEI 1126
Score = 36.2 bits (82), Expect = 0.087
Identities = 49/209 (23%), Positives = 94/209 (44%), Gaps = 21/209 (10%)
Query: 245 QDDGPEKLDPRYFGELLADLSRKNTDLYHCLLEHLQRIGGSKQDFESTDESEDIESLIPK 304
QDD E+L E A+L + + LE +R G + E D SE ++ L +
Sbjct: 1668 QDDLKEQLA---MVERRANLMQAEVEELRASLERTER-GRKMAEQELLDASERVQLLHTQ 1723
Query: 305 GLSEF-TKQQIRY-----------ILQMRGMSDKSLRLVLSTFSNIREELGHLQNDMTSL 352
S TK+++ I+Q +++ + ++ + + EEL Q+ L
Sbjct: 1724 NTSLINTKKKLETDISQIQGEMEDIVQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHL 1783
Query: 353 ENDKMRLEKDLSFKDTQLKEYEEL-LASVRANNHQQQQGLQDSSSKCQALEENNLSLRHT 411
E K +E+ + +L E E+L L + + + +++ S+ ++ +++N+
Sbjct: 1784 ERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELESEVESEQKHNVEAVKG 1843
Query: 412 LSDMEYRLKELEYCKRNLEQENQN-LRMQ 439
L E R+KEL Y E++ +N LR+Q
Sbjct: 1844 LRKHERRVKELTY---QTEEDRKNILRLQ 1869
Score = 32.7 bits (73), Expect = 0.96
Identities = 46/229 (20%), Positives = 93/229 (40%), Gaps = 31/229 (13%)
Query: 324 SDKSLRLVLSTFSNIREELG-------HLQNDMTSLENDKMRLEKDLSFKDTQLKEYEEL 376
++K + + F +EEL L+ M +L +K L+ + + L + EE
Sbjct: 849 TEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADALADAEER 908
Query: 377 --------------LASVRANNHQQQQGLQDSSSKCQALEENNLSLRHTLSDMEYRLKEL 422
+ V +++ + ++K + LE+ L+ + D+E L ++
Sbjct: 909 CDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKV 968
Query: 423 EYCKRNLEQENQNLRMQVSETC-TGPMLQAKMDEIGNHYTEMVKNLRMEKDREICRLRSQ 481
E K E + +NL +++ T L + + + + + +L+ME+D+
Sbjct: 969 EKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQMEEDK-------- 1020
Query: 482 LNQYHKDVSKREGSCSDFQFKLHELTSLLEEKDSLIKRQSEELSKLRQE 530
+N K +K E D + L + L + + KR+ E KL QE
Sbjct: 1021 VNTLTKAKTKLEQQVDDLEGSLEQEKKLCMDLER-AKRKLEGDLKLAQE 1068
>gi|31542634 filamin A interacting protein 1 [Homo sapiens]
Length = 1213
Score = 53.9 bits (128), Expect = 4e-07
Identities = 61/275 (22%), Positives = 120/275 (43%), Gaps = 48/275 (17%)
Query: 293 DESEDIESLIPKG---LSEFTKQQIRYILQMRGMSDKSLRLVLSTFSNIREELGHLQNDM 349
++S+D +L+ + L + +Q+ Y Q R + + RL + +R+EL L++
Sbjct: 195 NKSDDFTNLLEQERERLKKLLEQEKAY--QARKEKENAKRL-----NKLRDELVKLKSFA 247
Query: 350 TSLENDKMRLEKDLSFKDTQ-------LKEYEELLASVRANNHQQQQGL----------- 391
L +++ + L + + L+E EE L ++ + + + +Q L
Sbjct: 248 LMLVDERQMHIEQLGLQSQKVQDLTQKLREEEEKLKAITSKSKEDRQKLLKLEVDFEHKA 307
Query: 392 -------QDSSSKCQALEENNLSLRHTLSDMEYRLKELEYCKRNL---EQENQNLRMQVS 441
++ ++K E +N LR L + R++ELE +NL E+E Q LR +++
Sbjct: 308 SRFSQEHEEMNAKLANQESHNRQLRLKLVGLTQRIEELEETNKNLQKAEEELQELRDKIA 367
Query: 442 E-TCTGPMLQAKMDEIGNHYTEMVKNLRMEKDREICRLRSQLNQYHKDVSKREGSCSDFQ 500
+ C L A+++ + EM KD EI + SQ + K + + E + +
Sbjct: 368 KGECGNSSLMAEVENLRKRVLEM-----EGKDEEITKTESQCRELRKKLQEEEHHSKELR 422
Query: 501 FKLHELTSLLEEKDSLIKRQSEELSKLRQEIYSSH 535
++ +L + E + L E SK + E H
Sbjct: 423 LEVEKLQKRMSELEKL----EEAFSKSKSECTQLH 453
>gi|118498362 kinectin 1 isoform b [Homo sapiens]
Length = 1306
Score = 53.5 bits (127), Expect = 5e-07
Identities = 58/253 (22%), Positives = 112/253 (44%), Gaps = 32/253 (12%)
Query: 290 ESTDESEDIESLIPKGLSEFTKQQIRYILQMRGMSDKSLRLVLSTFSNIREELGHLQNDM 349
E ++ + +E L+ GL + ++ ++R S+ + ++L QND
Sbjct: 739 EKDEKLKTVEELLETGLIQVATKEEEL---------NAIRTENSSLTKEVQDLKAKQNDQ 789
Query: 350 TSLENDKMRLEKDLSFKDTQLKEYEELLASVRANNHQQQQGLQDS-SSKCQAL------- 401
S + L+K + KD ++K EELL + +++ +Q S +SK Q L
Sbjct: 790 VSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQLSITSKVQELQNLLKGK 849
Query: 402 EENNLSLRHTLSDMEYRLKELEYCKRNLEQENQNLRMQVSETCTGPMLQAKMDEIGNHYT 461
EE +++ L + E L ++L++EN++L+ V E + +A + +
Sbjct: 850 EEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQHNLKEASS---ASQFE 906
Query: 462 EMVKNLRMEKDREICRLRSQLNQYHKDVSKREGSCSDFQFKLHELTSLLEEKDSLIKRQS 521
E+ L+ EK+ E+ RL + L + D+S + D Q +++ L K Q
Sbjct: 907 ELEIVLK-EKENELKRLEAMLKERESDLSSKTQLLQDVQ-----------DENKLFKSQI 954
Query: 522 EELSKLRQEIYSS 534
E+L + + SS
Sbjct: 955 EQLKQQNYQQASS 967
Score = 47.0 bits (110), Expect = 5e-05
Identities = 50/229 (21%), Positives = 101/229 (44%), Gaps = 33/229 (14%)
Query: 336 SNIREELGHLQNDMTS----LENDKMRLEKDLSFKDTQLK--------EYEELLASVRAN 383
+ +R++ L N++T L+ ++++ +K+ TQLK +EE+ + +R
Sbjct: 449 NKLRQDYARLVNELTEKTGKLQQEEVQ-KKNAEQAATQLKVQLQEAERRWEEVQSYIRKR 507
Query: 384 NHQQQQGLQDSSSKCQALEENNLSLRHTLSD-------MEYRLKELEYCKRNLEQENQNL 436
+ + QD SK A E SL L+D +E RL +L ++ + ++L
Sbjct: 508 TAEHEAAQQDLQSKFVAKENEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESL 567
Query: 437 RMQVSETC-TGPMLQAKMDEIGNH---------YTEMVKNLRMEKDREICRLRSQLNQYH 486
+MQV + L+A++ + + E + + EKD++I + L
Sbjct: 568 QMQVQDILEQNEALKAQIQQFHSQIAAQTSASVLAEELHKVIAEKDKQIKQTEDSLASER 627
Query: 487 KDVSKREGSCSDFQFKLHELTSLLEEKDSLIKRQ---SEELSKLRQEIY 532
++ +E D Q L + +++ +L Q + EL K++Q +Y
Sbjct: 628 DRLTSKEEELKDIQNMNFLLKAEVQKLQALANEQAAAAHELEKMQQSVY 676
Score = 41.6 bits (96), Expect = 0.002
Identities = 56/274 (20%), Positives = 124/274 (45%), Gaps = 16/274 (5%)
Query: 266 RKNTDLYHCLLEHLQRIGGSKQDFESTDESEDIESLIPKGLSEFTKQQIRYILQMRGMSD 325
RK T + + LQ +K++ + S+ ++L+ K E Q+ Q R +
Sbjct: 505 RKRTAEHEAAQQDLQSKFVAKENEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKE 564
Query: 326 KSLRL----VLSTFSNIREELGHLQNDMTSLENDKM---RLEKDLSFKDTQLKEYEELLA 378
+SL++ +L ++ ++ + + + + + L K ++ KD Q+K+ E+ LA
Sbjct: 565 ESLQMQVQDILEQNEALKAQIQQFHSQIAAQTSASVLAEELHKVIAEKDKQIKQTEDSLA 624
Query: 379 SVRANNHQQQQGLQDSSSKCQALEENNLSLRHTLSDMEYRLKELEYCKRNLEQENQNLRM 438
S R +++ L+D + L+ L+ ++ ELE ++++ ++ +R+
Sbjct: 625 SERDRLTSKEEELKDIQNMNFLLKAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIRL 684
Query: 439 QVSETCTGPMLQAKMDEIGNHYTEMVKNLRMEKDREICRLRSQLN-QYHKDVSKREGSC- 496
E + KM+E +++ + E+ +L++ ++ Q +KDV ++ C
Sbjct: 685 --LEEQLQHEISNKMEEF-----KILNDQNKALKSEVQKLQTLVSEQPNKDVVEQMEKCI 737
Query: 497 SDFQFKLHELTSLLEEKDSLIKRQSEELSKLRQE 530
+ KL + LLE + + EEL+ +R E
Sbjct: 738 QEKDEKLKTVEELLETGLIQVATKEEELNAIRTE 771
Score = 34.3 bits (77), Expect = 0.33
Identities = 49/238 (20%), Positives = 103/238 (43%), Gaps = 47/238 (19%)
Query: 338 IREELGHLQNDMTSLENDKM--RLEKDLSFKDTQLKEYEELLA--------------SVR 381
++ E+ LQ ++ N + ++EK + KD +LK EELL ++R
Sbjct: 710 LKSEVQKLQTLVSEQPNKDVVEQMEKCIQEKDEKLKTVEELLETGLIQVATKEEELNAIR 769
Query: 382 ANNHQQQQGLQDSSSKCQALEENNLSLRHTLSDMEYRLKELEYCKRNLEQ--ENQNLRMQ 439
N + +QD +K + + +S + +++ + E + +++E+ E + L++
Sbjct: 770 TENSSLTKEVQDLKAK----QNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVA 825
Query: 440 VSETCTGPMLQAKMDEIGN------HYTEMVKNLRMEKDREICR--------------LR 479
E + +K+ E+ N +K + EK++++ L+
Sbjct: 826 NKEKTVQLSITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLK 885
Query: 480 SQLNQYHKDVSKREGSCSDFQFKLHELTSLLEEKDSLIKRQSEELSKLRQEIYSSHNQ 537
+ + + + K S S F+ EL +L+EK++ +KR E + K R+ SS Q
Sbjct: 886 AHVQEVAQHNLKEASSASQFE----ELEIVLKEKENELKR-LEAMLKERESDLSSKTQ 938
Score = 30.8 bits (68), Expect = 3.6
Identities = 31/153 (20%), Positives = 65/153 (42%), Gaps = 17/153 (11%)
Query: 324 SDKSLRLVLSTFSNIREELGHLQNDMTSLENDK-------MRLEKDLSFKDTQLKEYEEL 376
S K+++ + S+F++ +EL L+++ +EN + M LEK + T + E EL
Sbjct: 1148 SHKTIKQMQSSFTSSEQELERLRSENKDIENLRREREHLEMELEKAEMERSTYVTEVREL 1207
Query: 377 -------LASVRANNHQQQQGLQDSSSKCQALEENNLSLRHTLSDMEYRLKELEYCKRNL 429
L +R +++Q+ D Q+LE + D ++ +
Sbjct: 1208 KAQLNETLTKLRTEQNERQKVAGDLHKAQQSLELIQSKIVKAAGDTTV-IENSDVSPETE 1266
Query: 430 EQENQNLRMQVSETCTGPMLQAKMDEIGNHYTE 462
E + + + +++T T LQ + + T+
Sbjct: 1267 SSEKETMSVSLNQTVT--QLQQLLQAVNQQLTK 1297
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 53.5 bits (127), Expect = 5e-07
Identities = 56/254 (22%), Positives = 114/254 (44%), Gaps = 24/254 (9%)
Query: 297 DIESLIPKGLSEFTKQQIRYILQMRGMSDKSLRLVLSTFSNIREELGHLQNDMTSLENDK 356
++ES + K L E Q + + +K + + + EL L++ +L +K
Sbjct: 571 ELESSLEKSLQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEK 630
Query: 357 MRLEKDLSFKDTQLKEYEELLASVRANNHQQQQGL-QDSSSKCQA-LEENN------LSL 408
+++ K ++Y+ + +R Q+++ L +D QA +EE N L +
Sbjct: 631 LQVLK---------QQYQTEMEKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDV 681
Query: 409 RHT-LSDMEYRLKELEYCKRNLEQENQNLRMQVSETCTGPMLQAKMDEIGNHYTEMVKNL 467
+ T L + L E+ + LE+E L+ Q + L+AKMDE NH+ + V ++
Sbjct: 682 KQTELESLSSELSEVLKARHKLEEELSVLKDQTDKM--KQELEAKMDEQKNHHQQQVDSI 739
Query: 468 RMEKDREICR----LRSQLNQYHKDVSKREGSCSDFQFKLHELTSLLEEKDSLIKRQSEE 523
E + I R L+ Q+NQ + +R+ + Q + L + ++ + +++ S +
Sbjct: 740 IKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAK 799
Query: 524 LSKLRQEIYSSHNQ 537
L + ++H Q
Sbjct: 800 LDVFQSYQSATHEQ 813
Score = 44.3 bits (103), Expect = 3e-04
Identities = 69/295 (23%), Positives = 122/295 (41%), Gaps = 57/295 (19%)
Query: 277 EHLQRIGGSKQDFESTDESEDIESLIPKGLSE------FTKQQIRYI-LQMRGMSDK--S 327
E LQ+ GG++Q ++ E E + + K LSE K++++ +++ +S +
Sbjct: 1321 EALQKEGGNQQ--QAASEKESCITQLKKELSENINAVTLMKEELKEKKVEISSLSKQLTD 1378
Query: 328 LRLVLSTFSNIREELGHLQNDMTSLENDKMRL---EKDLSFK-DTQLKEYEELLASV--- 380
L + L ++ E+ + + + +K L +DLSFK DT KE L V
Sbjct: 1379 LNVQLQNSISLSEKEAAISSLRKQYDEEKCELLDQVQDLSFKVDTLSKEKISALEQVDDW 1438
Query: 381 -------------RANNHQQ-----QQGLQDSSSKCQALEENNLSLRHTLSDMEYRLK-- 420
R HQ Q L+ S + +E L+ L R
Sbjct: 1439 SNKFSEWKKKAQSRFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCL 1498
Query: 421 --ELEYCKRNLEQENQNLRMQVSETCTGPMLQAKMDEIGNHYTEMVKNLRMEKDREICRL 478
E+E K +E++ NL ++ A++ E+ +H T+ K + +E E+ +
Sbjct: 1499 KGEMEDDKSKMEKKESNLETELKSQT------ARIMELEDHITQ--KTIEIESLNEVLKN 1550
Query: 479 RSQLNQYHKDVSKREGSCSDFQFKLHELTSLLEEKDSLIKRQSEELSKLRQEIYS 533
+Q KD+ +E KL L EEKD+ +K E++ L ++YS
Sbjct: 1551 YNQ----QKDIEHKE-----LVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYS 1596
Score = 43.9 bits (102), Expect = 4e-04
Identities = 58/278 (20%), Positives = 110/278 (39%), Gaps = 38/278 (13%)
Query: 277 EHLQRIGGSKQDFESTDESEDIESLIPKGL-----SEFTKQQIRYILQMRGMSDKSLRLV 331
E LQ I + + ++ +++ L K L E ++I ++ + D +L +
Sbjct: 1056 EELQEI----HEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVKQDTTLNEL 1111
Query: 332 LSTFSNIREELGHLQNDMTSLENDKMRLEKDLSFKDTQLKEYEELLASVRANNHQQQQGL 391
+ L D T L+ +LE DL+ + +E L ++ + ++ +
Sbjct: 1112 QEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKV 1171
Query: 392 QDSSSKCQALEENNLSLRHTLSDMEYRLKELEYCKRNLEQENQNLRMQVSETC--TGPML 449
+ +SK + +E SL+ S E K LE ++ ++ L +Q+ C T +L
Sbjct: 1172 SELTSKLKTTDEEFQSLK---SSHEKSNKSLEDKSLEFKKLSEELAIQLDICCKKTEALL 1228
Query: 450 QAKMDEIGN-----------------HYTEMVKNLRMEKDREICRLRSQLNQYHKDVSKR 492
+AK +E+ N H T VK + K + L +QL Q ++
Sbjct: 1229 EAKTNELINISSSKTNAILSRISHCQHRTTKVKEALLIKTCTVSELEAQLRQLTEEQ--- 1285
Query: 493 EGSCSDFQFKLHELTSLLEEKDSLIKRQSEELSKLRQE 530
+ + T LEEK++ IK ++ L E
Sbjct: 1286 ----NTLNISFQQATHQLEEKENQIKSMKADIESLVTE 1319
Score = 42.7 bits (99), Expect = 0.001
Identities = 49/232 (21%), Positives = 104/232 (44%), Gaps = 44/232 (18%)
Query: 336 SNIREELGHLQNDMTSLENDKMRLEKDLSFKDTQLKEYEELLASVRANNHQQQQGLQDSS 395
S I+E +Q +L++ +LE L +D LKE++ + ++ A+ + + LQ +S
Sbjct: 738 SIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQAS 797
Query: 396 SK--------------CQALEENNLSLRHTLSDME-------YRLKELEYCKRNL----- 429
+K +A EE L+ L D+E ++ E+E K+++
Sbjct: 798 AKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELD 857
Query: 430 -----------EQENQNLRMQVSETCTGPMLQAKMDEIGNHYTEMVKNLRMEKDREICRL 478
+ E QN M+ + ++K+++ GN E K + +EK+ I ++
Sbjct: 858 AHKIQVQDLMQQLEKQNSEMEQKVKSLTQVYESKLED-GNKEQEQTKQILVEKENMILQM 916
Query: 479 RSQLNQYHKDVSKREGSCSDFQFKLHELTSLLEEKDSLIKRQSEELSKLRQE 530
R + + ++++ + D +H L EE ++ K Q +++ K++Q+
Sbjct: 917 REGQKKEIEILTQKLSAKED---SIHILN---EEYETKFKNQEKKMEKVKQK 962
Score = 42.0 bits (97), Expect = 0.002
Identities = 65/327 (19%), Positives = 129/327 (39%), Gaps = 30/327 (9%)
Query: 253 DPRYFGELLADLSRKNTDLYHCLLEHLQRIGGSKQDFESTDESEDIESLIPKGLSE---- 308
D G L +L KN + +H+++ GG K + ++ E++ + K L E
Sbjct: 1790 DQSMIGHLQEELEEKNKKYSLIVAQHVEKEGG-KNNIQAKQNLENVFDDVQKTLQEKELT 1848
Query: 309 --FTKQQIRYILQMRGMSDKSLRLVLSTFSNIREELGHLQNDMTSLENDKMRLEKDLSFK 366
+Q+I+ + + R+ + ++ E+L LQ M LE++ K
Sbjct: 1849 CQILEQKIKELDSCLVRQKEVHRVEMEELTSKYEKLQALQ-QMDGRNKPTELLEENTEEK 1907
Query: 367 DTQLKEYEELLASVRANNHQQQQGLQDSSSKCQALEENNLSLRHTLSDM-EYRLKELEYC 425
+LL+++ A ++ + L + + Q L + + L+ L + + +ELE
Sbjct: 1908 SKSHLVQPKLLSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQKDLRMLRKEHQQELEIL 1967
Query: 426 KRNLEQENQNLRMQVSETCT---GPMLQAKMDEIGNHYTEMVKNLRM----------EKD 472
K+ +QE + Q E L+ M E + + L M E +
Sbjct: 1968 KKEYDQEREEKIKQEQEDLELKHNSTLKQLMREFNTQLAQKEQELEMTIKETINKAQEVE 2027
Query: 473 REICRL-RSQLNQYHKDVSKREGSCSDFQFKLHELTSLLEEKDSL----IKRQSEELSKL 527
E+ + + NQ K +++++ + E+ EE+ + ++ Q EEL K
Sbjct: 2028 AELLESHQEETNQLLKKIAEKDDDLKRTAKRYEEILDAREEEMTAKVRDLQTQLEELQKK 2087
Query: 528 RQEIYSSHNQPSTGGRTTITTKKYRTQ 554
Q+ P G +T + +TQ
Sbjct: 2088 YQQKLEQEENP---GNDNVTIMELQTQ 2111
Score = 32.0 bits (71), Expect = 1.6
Identities = 48/200 (24%), Positives = 87/200 (43%), Gaps = 39/200 (19%)
Query: 366 KDTQLKEYEELLASVRANNHQQQQGLQDSSSKCQALEENNLSLR---HTLSDMEYRLK-- 420
KD ++KE EE + ++ + + L+ +K + LE NLS++ L +E RL+
Sbjct: 1576 KDNRVKEAEEKILTLENQVYSMKAELE---TKKKELEHVNLSVKSKEEELKALEDRLESE 1632
Query: 421 ---ELEYCKRNLEQENQNLRMQVSETCTGPMLQAKMDEIGNHYTEMVKNLRMEKDREICR 477
+L KR EQ+ ++ Q+ Q K +H +E+ L+ E++RE+
Sbjct: 1633 SAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQYKKG-TESHLSELNTKLQ-EREREVHI 1690
Query: 478 LRSQLNQYHKDVS----------------KREGSCSD------FQFKLHELTSLLEEKDS 515
L +L S ++E + S ++ K+ L L EK+
Sbjct: 1691 LEEKLKSVESSQSETLIVPRSAKNVAAYTEQEEADSQGCVQKTYEEKISVLQRNLTEKEK 1750
Query: 516 LIKRQSEELSKLRQEIYSSH 535
L++R +E ++E SSH
Sbjct: 1751 LLQRVGQE----KEETVSSH 1766
>gi|150010604 kinesin family member 4B [Homo sapiens]
Length = 1234
Score = 52.8 bits (125), Expect = 9e-07
Identities = 70/291 (24%), Positives = 130/291 (44%), Gaps = 42/291 (14%)
Query: 279 LQRIGGSKQDFESTDESEDIESLIPKGLS--EFTKQQIRYILQMRGMSDKSLRLVLSTFS 336
LQ GG+ + + SE+++SL+ K S E ++ R + + G + + L ++ T
Sbjct: 366 LQAHGGTLPGSINAEPSENLQSLMEKNQSLVEENEKLSRCLSKAAGQTAQMLERIILT-E 424
Query: 337 NIREELGHLQNDMTSLENDKMRLEKDL-SFKDTQLKEYEELLASVRANNHQQQQGLQDSS 395
+ E+L ++ K+ L+K + + +D +LKE E++ +++ Q L D +
Sbjct: 425 QVNEKLNAKLEELRQHVACKLDLQKLVETLEDQELKENVEIICNLQ----QLITQLSDET 480
Query: 396 SKCQA------LEE--------------NNLSLRHTLSDMEYRLKELEYCKRNLEQENQN 435
C A +EE + + +H L + + +E +E
Sbjct: 481 VACTAAAIDTAVEEEAQVETSPETSRSSDAFTTQHALHQAQMSKEVVELNNALALKEALV 540
Query: 436 LRMQVSETCTGPMLQAKMDEIGNHYTEMVKNLRMEKD---REICRLRSQLNQY------H 486
+M ++ P+ D I N E++ NL+ EK+ RE+ + +NQ H
Sbjct: 541 RKMTQNDNQLQPIQFQYQDNIKNLELEVI-NLQKEKEELVRELQTAKKNVNQAKLSEHRH 599
Query: 487 KDVSKREGSCSDFQFKLHELTSLLEEKDSLIKRQSEELSKLRQEIYSSHNQ 537
K + + EG +D + KL+E + LL+ K+S +SKL QEI+ NQ
Sbjct: 600 KLLQELEGQIADLKKKLNEQSKLLKLKES----TERTVSKLNQEIWMMKNQ 646
>gi|58530842 desmoplakin isoform II [Homo sapiens]
Length = 2272
Score = 52.4 bits (124), Expect = 1e-06
Identities = 56/207 (27%), Positives = 93/207 (44%), Gaps = 27/207 (13%)
Query: 358 RLEKDLSFKDTQLKEYEELLASVRANNHQQQQGLQDSSSKCQALEENNLSLRHTLSDMEY 417
RL L + T+ +EYE LA +A+N +Q+S ++C + + SL + +E
Sbjct: 1173 RLRVLLQEEGTRKREYENELA--KASNR-----IQESKNQCTQVVQERESLLVKIKVLEQ 1225
Query: 418 ------RLK-ELEYCKRNLEQENQNLRMQVSETCTGPMLQAKMDEIGNHYT---EMVKNL 467
RL+ EL K LE E R++ C +Q +++ Y+ E ++ +
Sbjct: 1226 DKARLQRLEDELNRAKSTLEAET---RVKQRLECEKQQIQNDLNQWKTQYSRKEEAIRKI 1282
Query: 468 RMEKD---REICRLRSQLNQYHKDVSKREGSCS-DFQFKLHELTSLLEEKDSLIKRQSEE 523
E++ RE LRS++ + ++ + E C + E S LE + S R E
Sbjct: 1283 ESEREKSEREKNSLRSEIERLQAEIKRIEERCRRKLEDSTRETQSQLETERS---RYQRE 1339
Query: 524 LSKLRQEIYSSHNQPSTGGRTTITTKK 550
+ KLRQ Y SH + T T+ T K
Sbjct: 1340 IDKLRQRPYGSHRETQTECEWTVDTSK 1366
Score = 42.4 bits (98), Expect = 0.001
Identities = 43/201 (21%), Positives = 84/201 (41%), Gaps = 30/201 (14%)
Query: 354 NDKMRLEKDLSFKDTQLKEYEELLASVRANNHQQQQGLQDSSSKCQALEENNLSLRHTLS 413
++ ++ +DL K+T+++ EE L R N ++ +K + L++N + S
Sbjct: 1018 SEMLKSLEDLKLKNTKIEVLEEELRLARDAN-------SENCNKNKFLDQNLQKYQAECS 1070
Query: 414 DMEYRLKELEYCKRNLEQENQNLRMQVSETCTGPMLQAKMDEIGNHYTEMVKNLRMEKDR 473
+ +L LE KR E + ++ + + + C G ++ E+ T + + EK R
Sbjct: 1071 QFKAKLASLEELKRQAELDGKSAKQNL-DKCYG-----QIKELNEKITRLTYEIEDEKRR 1124
Query: 474 EIC---RLRSQLNQYHKDVSKR--------------EGSCSDFQFKLHELTSLLEEKDSL 516
R Q N Y + R E + + ++++ L LL+E+ +
Sbjct: 1125 RKSVEDRFDQQKNDYDQLQKARQCEKENLGWQKLESEKAIKEKEYEIERLRVLLQEEGTR 1184
Query: 517 IKRQSEELSKLRQEIYSSHNQ 537
+ EL+K I S NQ
Sbjct: 1185 KREYENELAKASNRIQESKNQ 1205
>gi|36031016 CTCL tumor antigen L14-2 [Homo sapiens]
Length = 898
Score = 52.4 bits (124), Expect = 1e-06
Identities = 66/275 (24%), Positives = 122/275 (44%), Gaps = 30/275 (10%)
Query: 277 EHLQRIGGSKQDFEST-DESEDIES-------LIPKGLSEFTKQQIRYILQMRGMSDKSL 328
E +I + QD T ESE+I+S + KG E Q+ L+M K L
Sbjct: 425 EEADQIRKNCQDMIKTYQESEEIKSNELDAKLRVTKGELEKQMQEKSDQLEMHHAKIKEL 484
Query: 329 RLVLSTFSNIREELGHLQNDMTSLENDKMRLEKDLS-FKD---TQLKEYEELLASVRANN 384
+ TF +EL L+ + LE++++R E +LS +K+ Q E + LL V+ +
Sbjct: 485 EDLKRTFKEGMDELRTLRTKVKCLEDERLRTEDELSKYKEIINRQKAEIQNLLDKVKTAD 544
Query: 385 HQQQQGLQDSSSKCQALEENNLSLRHTLSDME-------YRLKELEYCKRNLEQENQNLR 437
Q+Q LQ + + L+E SL ++D++ R EL L +N L+
Sbjct: 545 QLQEQ-LQRGKQEIENLKEEVESLNSLINDLQKDIEGSRKRESELLLFTERLTSKNAQLQ 603
Query: 438 MQVSETCTGPMLQAKMDEIGNHYTEMVKNLRMEKDREI---CRLRSQLNQYHKDVSKREG 494
+ + LQ++ D++ +++ K I RL + ++V +
Sbjct: 604 SESNS------LQSQFDKVSCSESQLQSQCEQMKQTNINLESRLLKEEELRKEEVQTLQA 657
Query: 495 SCSDFQFKLHELTSLLEE-KDSLIKRQSEELSKLR 528
+ Q ++ L++ +EE KD L+ ++ + S ++
Sbjct: 658 ELACRQTEVKALSTQVEELKDELVTQRRKHASSIK 692
>gi|38044112 restin isoform b [Homo sapiens]
Length = 1392
Score = 52.0 bits (123), Expect = 2e-06
Identities = 46/203 (22%), Positives = 91/203 (44%), Gaps = 15/203 (7%)
Query: 336 SNIREELGHLQNDMTSLENDKMRLEKDLSFKDTQLKEYEELLASVRANNHQQQQGLQDSS 395
+N++E L + + K LEK+L + E E SV+ + + L
Sbjct: 787 TNLQENL-------SEVSQVKETLEKELQILKEKFAEASEEAVSVQRSMQETVNKLHQKE 839
Query: 396 SKCQALEENNLSLRHTLSDMEYRLKELEYCKRNLEQENQNLRMQVSETCTGPMLQAKMDE 455
+ L + LR L+DME + +E + + L + + L ++E + +
Sbjct: 840 EQFNMLSSDLEKLRENLADMEAKFREKDEREEQLIKAKEKLENDIAE------IMKMSGD 893
Query: 456 IGNHYTEMVKNLRMEKDREICRLRSQLNQYHKDVSKREGSCSDFQFKLHELTSLLEEKDS 515
+ T+M LR+ K+R++ L+ +L + +++ S + S D K + +K
Sbjct: 894 NSSQLTKMNDELRL-KERDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKKHE 952
Query: 516 LIKRQSE-ELSKLRQEIYSSHNQ 537
K++ E +LS L +++ +SHNQ
Sbjct: 953 EEKKELERKLSDLEKKMETSHNQ 975
Score = 45.4 bits (106), Expect = 1e-04
Identities = 47/217 (21%), Positives = 94/217 (43%), Gaps = 41/217 (18%)
Query: 280 QRIGGSKQDFESTDESEDIESLIPKGLSEFTKQQIRYIL---QMRGMSDKSLRLVLSTFS 336
+ +G S+ + S + E+ S++ L E K++ ++I + + KS+ + + +
Sbjct: 1138 EELGRSRDEVTSHQKLEEERSVLNNQLLEMKKRESKFIKDADEEKASLQKSISITSALLT 1197
Query: 337 NIREELGHLQNDMT-----------------SLENDKMRLEKDLSFKDTQLKEYEELLAS 379
EL L+N++T +LE+DK++LE + + QLKE + L+S
Sbjct: 1198 EKDAELEKLRNEVTVLRGENASAKSLHSVVQTLESDKVKLELKVKNLELQLKENKRQLSS 1257
Query: 380 VRANNHQQQQGLQDSSSKCQALEENNLSLRHTLSDMEYRLKELEYCKRNLEQENQNLRMQ 439
N Q D + Q E ++ L +L+++NQ+L+M+
Sbjct: 1258 SSGNTDTQ----ADEDERAQ----------------ESQIDFLNSVIVDLQRKNQDLKMK 1297
Query: 440 VSETCTGPMLQAKMDEIGNHYTEMVKNLRMEKDREIC 476
V E + L D++ N+ ++ + +K R C
Sbjct: 1298 V-EMMSEAALNGNGDDLNNYDSDDQEKQSKKKPRLFC 1333
Score = 40.8 bits (94), Expect = 0.004
Identities = 61/294 (20%), Positives = 113/294 (38%), Gaps = 52/294 (17%)
Query: 257 FGELLADLSRKNTDLYHCLLEHLQRIGGSKQDFESTDESEDIESLIPKGLSEFTKQQIRY 316
F EL + + D H +E+LQ ++QD E ++++E+L K L + K++
Sbjct: 610 FAELKTQIEKMRLDYQH-EIENLQ----NQQDSERAAHAKEMEALRAK-LMKVIKEKENS 663
Query: 317 ILQMRGMSDKSLRLVLSTFSNIREELGHLQNDMTSLENDKMRLEKDLSFKD---TQLKEY 373
+ +R DK+ L + +L + + LE + + + D +QLK
Sbjct: 664 LEAIRSKLDKAEDQHLVEMEDTLNKLQEAEIKVKELEVLQAKCNEQTKVIDNFTSQLKAT 723
Query: 374 EELLASVRANNHQQQQGLQDSSSKCQALEENNLSLRHT---------------------- 411
EE L + A +G + Q LE ++H
Sbjct: 724 EEKLLDLDALRKASSEGKSEMKKLRQQLEAAEKQIKHLEIEKNAESSKASSITRELQGRE 783
Query: 412 --LSDMEYRLKELEYCKRNLEQENQNLRMQVSETCTGPM-LQAKMDEIGNHYTEMVKNLR 468
L++++ L E+ K LE+E Q L+ + +E + +Q M E N
Sbjct: 784 LKLTNLQENLSEVSQVKETLEKELQILKEKFAEASEEAVSVQRSMQETVN---------- 833
Query: 469 MEKDREICRLRSQLNQYHKDVSKREGSCSDFQFKLHELTSLLEEKDSLIKRQSE 522
++ + Q N D+ K + +D + K E E ++ LIK + +
Sbjct: 834 -----KLHQKEEQFNMLSSDLEKLRENLADMEAKFREKD---EREEQLIKAKEK 879
>gi|4506751 restin isoform a [Homo sapiens]
Length = 1427
Score = 52.0 bits (123), Expect = 2e-06
Identities = 46/203 (22%), Positives = 91/203 (44%), Gaps = 15/203 (7%)
Query: 336 SNIREELGHLQNDMTSLENDKMRLEKDLSFKDTQLKEYEELLASVRANNHQQQQGLQDSS 395
+N++E L + + K LEK+L + E E SV+ + + L
Sbjct: 822 TNLQENL-------SEVSQVKETLEKELQILKEKFAEASEEAVSVQRSMQETVNKLHQKE 874
Query: 396 SKCQALEENNLSLRHTLSDMEYRLKELEYCKRNLEQENQNLRMQVSETCTGPMLQAKMDE 455
+ L + LR L+DME + +E + + L + + L ++E + +
Sbjct: 875 EQFNMLSSDLEKLRENLADMEAKFREKDEREEQLIKAKEKLENDIAE------IMKMSGD 928
Query: 456 IGNHYTEMVKNLRMEKDREICRLRSQLNQYHKDVSKREGSCSDFQFKLHELTSLLEEKDS 515
+ T+M LR+ K+R++ L+ +L + +++ S + S D K + +K
Sbjct: 929 NSSQLTKMNDELRL-KERDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKKHE 987
Query: 516 LIKRQSE-ELSKLRQEIYSSHNQ 537
K++ E +LS L +++ +SHNQ
Sbjct: 988 EEKKELERKLSDLEKKMETSHNQ 1010
Score = 45.4 bits (106), Expect = 1e-04
Identities = 47/217 (21%), Positives = 94/217 (43%), Gaps = 41/217 (18%)
Query: 280 QRIGGSKQDFESTDESEDIESLIPKGLSEFTKQQIRYIL---QMRGMSDKSLRLVLSTFS 336
+ +G S+ + S + E+ S++ L E K++ ++I + + KS+ + + +
Sbjct: 1173 EELGRSRDEVTSHQKLEEERSVLNNQLLEMKKRESKFIKDADEEKASLQKSISITSALLT 1232
Query: 337 NIREELGHLQNDMT-----------------SLENDKMRLEKDLSFKDTQLKEYEELLAS 379
EL L+N++T +LE+DK++LE + + QLKE + L+S
Sbjct: 1233 EKDAELEKLRNEVTVLRGENASAKSLHSVVQTLESDKVKLELKVKNLELQLKENKRQLSS 1292
Query: 380 VRANNHQQQQGLQDSSSKCQALEENNLSLRHTLSDMEYRLKELEYCKRNLEQENQNLRMQ 439
N Q D + Q E ++ L +L+++NQ+L+M+
Sbjct: 1293 SSGNTDTQ----ADEDERAQ----------------ESQIDFLNSVIVDLQRKNQDLKMK 1332
Query: 440 VSETCTGPMLQAKMDEIGNHYTEMVKNLRMEKDREIC 476
V E + L D++ N+ ++ + +K R C
Sbjct: 1333 V-EMMSEAALNGNGDDLNNYDSDDQEKQSKKKPRLFC 1368
Score = 40.8 bits (94), Expect = 0.004
Identities = 61/294 (20%), Positives = 113/294 (38%), Gaps = 52/294 (17%)
Query: 257 FGELLADLSRKNTDLYHCLLEHLQRIGGSKQDFESTDESEDIESLIPKGLSEFTKQQIRY 316
F EL + + D H +E+LQ ++QD E ++++E+L K L + K++
Sbjct: 645 FAELKTQIEKMRLDYQH-EIENLQ----NQQDSERAAHAKEMEALRAK-LMKVIKEKENS 698
Query: 317 ILQMRGMSDKSLRLVLSTFSNIREELGHLQNDMTSLENDKMRLEKDLSFKD---TQLKEY 373
+ +R DK+ L + +L + + LE + + + D +QLK
Sbjct: 699 LEAIRSKLDKAEDQHLVEMEDTLNKLQEAEIKVKELEVLQAKCNEQTKVIDNFTSQLKAT 758
Query: 374 EELLASVRANNHQQQQGLQDSSSKCQALEENNLSLRHT---------------------- 411
EE L + A +G + Q LE ++H
Sbjct: 759 EEKLLDLDALRKASSEGKSEMKKLRQQLEAAEKQIKHLEIEKNAESSKASSITRELQGRE 818
Query: 412 --LSDMEYRLKELEYCKRNLEQENQNLRMQVSETCTGPM-LQAKMDEIGNHYTEMVKNLR 468
L++++ L E+ K LE+E Q L+ + +E + +Q M E N
Sbjct: 819 LKLTNLQENLSEVSQVKETLEKELQILKEKFAEASEEAVSVQRSMQETVN---------- 868
Query: 469 MEKDREICRLRSQLNQYHKDVSKREGSCSDFQFKLHELTSLLEEKDSLIKRQSE 522
++ + Q N D+ K + +D + K E E ++ LIK + +
Sbjct: 869 -----KLHQKEEQFNMLSSDLEKLRENLADMEAKFREKD---EREEQLIKAKEK 914
Score = 32.0 bits (71), Expect = 1.6
Identities = 49/274 (17%), Positives = 114/274 (41%), Gaps = 28/274 (10%)
Query: 276 LEHLQRIGGSKQDFESTDESEDIESLIPKGLSEFTKQQIRYILQMRGMSDKSLRLVLSTF 335
+E L ++ K+ E + ES+ L TK + I ++ ++SL +
Sbjct: 425 VELLNQLEEEKRKVEDLQFRVEEESITKGDLETQTKLEHARIKEL----EQSLLFEKTKA 480
Query: 336 SNIREELGHLQNDMTSLENDKMRLEKDLSFKDTQLKEYEELLASVR--ANNHQQQQGLQD 393
++ EL + S ++ M LEKDL+ + ++ E L S + + LQ+
Sbjct: 481 DKLQRELEDTRVATVSEKSRIMELEKDLALRVQEVAELRRRLESNKPAGDVDMSLSLLQE 540
Query: 394 SSSKCQALEENNLSLRHTLSDM-----------EYRLKELEYCKRNLEQENQNLRMQV-- 440
SS + LE + ++ + + +K L L +EN++L+ ++
Sbjct: 541 ISSLQEKLEVTRTDHQREITSLKEHFGAREETHQKEIKALYTATEKLSKENESLKSKLEH 600
Query: 441 ---SETCTGPMLQAKMDEIGNHYTEMVKNLRMEKDREICRLRSQLNQYHKDVSKREGSCS 497
+ + ++K++ + + ++ L++ + + ++ + + K
Sbjct: 601 ANKENSDVIALWKSKLETAIASHQQAMEELKVSFSKGLGTETAEFAELKTQIEKMR---L 657
Query: 498 DFQFKLHELTSLLEEKDSLIKRQSEELSKLRQEI 531
D+Q HE+ +L ++DS ++E+ LR ++
Sbjct: 658 DYQ---HEIENLQNQQDSERAAHAKEMEALRAKL 688
>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
sapiens]
Length = 1938
Score = 52.0 bits (123), Expect = 2e-06
Identities = 67/368 (18%), Positives = 153/368 (41%), Gaps = 64/368 (17%)
Query: 164 VIYEKTIRKVEKLNTDQGCHPQAQCHHHIIQQPQVIHSAHWQQPDSSQQIQAITGNNPIS 223
+I++ ++K +L T G + H + ++ +I + +QQ++ +
Sbjct: 1273 LIHDLNMQKA-RLQTQNG-----ELSHRVEEKESLISQLTKSKQALTQQLEELKRQMEEE 1326
Query: 224 THIGNELCHSGSSQICEQVIIQDDGPEKLDPRYFGELLADLSRKNTDLYHCLLEHLQRIG 283
T N + H+ S + ++++ E+ + + EL LS+ N+++ ++
Sbjct: 1327 TKAKNAMAHALQSSRHDCDLLREQYEEEQEAK--AELQRALSKANSEVAQWRTKY----- 1379
Query: 284 GSKQDFESTDESEDIESLIPKGLSEFTKQQIRYILQMRGMSDKSLRLVLSTFSNIREELG 343
+ T+E E+ + + + L E ++++ S +++ +
Sbjct: 1380 -ETDAIQRTEELEEAKKKLAQRLQE---------------AEENTETANSKCASLEKTKQ 1423
Query: 344 HLQNDMTSLENDKMRLEKDLSFKDTQLKEYEELLASVRANNHQQQQGLQDSSSKCQALEE 403
LQ ++ L D R + D + + ++++LA + +Q L +S ++ +A ++
Sbjct: 1424 RLQGEVEDLMRDLERSHTACATLDKKQRNFDKVLA-------EWKQKLDESQAELEAAQK 1476
Query: 404 NNLSLRHTLSDMEYRLKELEYCKRNLEQENQNLRMQVSETCTGPMLQAKMDEIGNHYTEM 463
+ SL L M +E+ L +EN+NL+ ++S+ L ++ E G + E
Sbjct: 1477 ESRSLSTELFKMRNAYEEVVDQLETLRRENKNLQEEISD------LTEQIAETGKNLQEA 1530
Query: 464 VKNLRMEKDREICRLRSQLNQYHKDVSKREGSCSDFQFKLHELTSLLEEKDSLIKRQSEE 523
K ++ + + SD Q L E+ LE ++S I R E
Sbjct: 1531 EKTKKLVEQEK----------------------SDLQVALEEVEGSLEHEESKILRVQLE 1568
Query: 524 LSKLRQEI 531
LS+++ E+
Sbjct: 1569 LSQVKSEL 1576
Score = 46.2 bits (108), Expect = 8e-05
Identities = 53/244 (21%), Positives = 103/244 (42%), Gaps = 39/244 (15%)
Query: 325 DKSLRLVLSTFSNIRE-ELGHLQNDMTSLENDKMRLEKDLSFKDTQLKEYEELLASVRAN 383
+K LR L E +L Q + LENDK ++E+ L K+ +L + + + + +
Sbjct: 1045 EKKLRADLERAKRKLEGDLKMSQESIMDLENDKQQIEEKLKKKEFELSQLQAKIDDEQVH 1104
Query: 384 NHQQQQGLQDSSSKCQALEENNLSLRHTL--------SDMEYRLKELE------------ 423
+ Q Q+ +++ ++ + LEE + HTL SD+ L+E+
Sbjct: 1105 SLQFQKKIKELQARIEELEE-EIEAEHTLRAKIEKQRSDLARELEEISERLEEASGATSA 1163
Query: 424 --YCKRNLEQENQNLRMQVSET-----CTGPMLQAKMDEIGNHYTEMVKNL-----RMEK 471
+ E E Q +R + E T L+ K + E + NL ++EK
Sbjct: 1164 QIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKQADSVAELGEQIDNLQRVKQKLEK 1223
Query: 472 DR-----EICRLRSQLNQYHKDVSKREGSCSDFQFKLHELTSLLEEKDSLIKRQSEELSK 526
++ EI + S + K S E +C + + E+ + E++ LI + + ++
Sbjct: 1224 EKSELKMEIDDMASNIEALSKSKSNIERTCRTVEDQFSEIKAKDEQQTQLIHDLNMQKAR 1283
Query: 527 LRQE 530
L+ +
Sbjct: 1284 LQTQ 1287
Score = 45.4 bits (106), Expect = 1e-04
Identities = 57/251 (22%), Positives = 101/251 (40%), Gaps = 41/251 (16%)
Query: 327 SLRLVLSTFSNIREELGHLQNDMTSLENDKMRLEKDLSFK--------DTQLKEYEEL-- 376
S R + T ++R G L++ L+ D +R +DL + L+E EE+
Sbjct: 1636 SNRQMAETQKHLRTVQGQLKDSQLHLD-DALRSNEDLKEQLAIVERRNGLLLEELEEMKV 1694
Query: 377 -LASVRANNHQQQQGLQDSSSKCQALEENNLSLRHTLSDMEYRLKELEYCKRNLEQENQN 435
L +Q L D+S + Q L N SL +T +E + + + N QE++N
Sbjct: 1695 ALEQTERTRRLSEQELLDASDRVQLLHSQNTSLINTKKKLEADIAQCQAEVENSIQESRN 1754
Query: 436 LRMQVSETCTGPMLQA----KMDEIGNHYTEMVKNLRME-KD-----------------R 473
+ + T + A K + H M KNL KD +
Sbjct: 1755 AEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKK 1814
Query: 474 EICRLRSQLNQYHK--DVSKREGS-----CSDFQFKLHELTSLLEEKDSLIKRQSEELSK 526
+I +L +++ + DV ++ G+ ++ K+ E+T EE I R + + K
Sbjct: 1815 QIQKLENRVRELENELDVEQKRGAEALKGAHKYERKVKEMTYQAEEDHKNILRLQDLVDK 1874
Query: 527 LRQEIYSSHNQ 537
L+ ++ S Q
Sbjct: 1875 LQAKVKSYKRQ 1885
Score = 44.7 bits (104), Expect = 2e-04
Identities = 43/206 (20%), Positives = 93/206 (45%), Gaps = 23/206 (11%)
Query: 346 QNDMTSLENDKMRLEKDLSFKDTQLKEYEELLASVRANNHQQQ-------QGLQDSSSKC 398
+ +M +++ D R +++L+ + + KE EE + S+ + Q + L D+ +C
Sbjct: 850 EKEMATMKEDFERTKEELARSEARRKELEEKMVSLLQEKNDLQLQVQSETENLMDAEERC 909
Query: 399 QALEENNLSLRHTLSDMEYRLKELEYC-------KRNLEQENQNLRMQVSETCTGPMLQA 451
+ L ++ + L + ++ RL+E E KRNLE + +L+ + + +
Sbjct: 910 EGLIKSKILLEAKVKELTERLEEEEEMNSELVAKKRNLEDKCSSLKRDIDDL---ELTLT 966
Query: 452 KMDEIGNHYTEMVKNLRMEK---DREICRL---RSQLNQYHKDVSKREGSCSDFQFKLHE 505
K+++ + VKNL E + I +L + L + H+ D L +
Sbjct: 967 KVEKEKHATENKVKNLSEEMTALEENISKLTKEKKSLQEAHQQTLDDLQVEEDKVNGLIK 1026
Query: 506 LTSLLEEKDSLIKRQSEELSKLRQEI 531
+ + LE++ ++ E+ KLR ++
Sbjct: 1027 INAKLEQQTDDLEGSLEQEKKLRADL 1052
Score = 41.6 bits (96), Expect = 0.002
Identities = 46/193 (23%), Positives = 82/193 (42%), Gaps = 28/193 (14%)
Query: 339 REELGHLQNDMTSLENDKMRLEKDLSFKDTQL-------KEYEELLASVRANNHQQQQGL 391
R +L H QN TSL N K +LE D++ ++ + EE + + L
Sbjct: 1716 RVQLLHSQN--TSLINTKKKLEADIAQCQAEVENSIQESRNAEEKAKKAITDAAMMAEEL 1773
Query: 392 QDSSSKCQALEENNLSLRHTLSDMEYRLKELE-YCKRNLEQENQNLRMQVSETCTGPMLQ 450
+ LE +L T+ D+++RL E E + +++ Q L +V E L+
Sbjct: 1774 KKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLENRVRE------LE 1827
Query: 451 AKMDEIGNHYTEMVKNLRMEKDREICRLRSQLNQYHKDVSKREGSCSDFQFKLHELTSLL 510
++D E +K + +R++ + Q + HK++ +L +L L
Sbjct: 1828 NELDVEQKRGAEALKGAH-KYERKVKEMTYQAEEDHKNI-----------LRLQDLVDKL 1875
Query: 511 EEKDSLIKRQSEE 523
+ K KRQ+EE
Sbjct: 1876 QAKVKSYKRQAEE 1888
Score = 39.3 bits (90), Expect = 0.010
Identities = 56/266 (21%), Positives = 113/266 (42%), Gaps = 44/266 (16%)
Query: 286 KQDFESTDESEDIESLIPKGLSEFTKQQIRYILQMRGMSDKSLRLVLSTFSNIREELGHL 345
K+DFE T E K L E + + ++ +D L++ T E L
Sbjct: 857 KEDFERTKEELARSEARRKELEE------KMVSLLQEKNDLQLQVQSET-----ENLMDA 905
Query: 346 QNDMTSLENDKMRLEKDLSFKDTQLKEYEELLASVRANNHQQQQGLQDSSSKCQALEENN 405
+ L K+ LE + +L+E EE+ + + A +++ L+D KC +L+ +
Sbjct: 906 EERCEGLIKSKILLEAKVKELTERLEEEEEMNSELVA----KKRNLED---KCSSLKRDI 958
Query: 406 LSLRHTLSDMEYRLKELEYCKRNLEQENQNLRMQVSETCTGPMLQAKMDEIGNHYTEMVK 465
L TL+ +E E +NL +E L +S+ L + + + + +
Sbjct: 959 DDLELTLTKVEKEKHATENKVKNLSEEMTALEENISK------LTKEKKSLQEAHQQTLD 1012
Query: 466 NLRMEKDR--EICRLRSQLNQYHKDVS------------------KREGSCSDFQFKLHE 505
+L++E+D+ + ++ ++L Q D+ K EG Q + +
Sbjct: 1013 DLQVEEDKVNGLIKINAKLEQQTDDLEGSLEQEKKLRADLERAKRKLEGDLKMSQESIMD 1072
Query: 506 LTSLLEEKDSLIKRQSEELSKLRQEI 531
L + ++ + +K++ ELS+L+ +I
Sbjct: 1073 LENDKQQIEEKLKKKEFELSQLQAKI 1098
Score = 35.0 bits (79), Expect = 0.19
Identities = 50/211 (23%), Positives = 85/211 (40%), Gaps = 29/211 (13%)
Query: 261 LADLSRKNTDLYH---CLLEHLQRIGGSKQDFEST-----DESEDIESLIPK---GLSEF 309
L L R+N +L L E + G + Q+ E T E D++ + + L
Sbjct: 1499 LETLRRENKNLQEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLEHE 1558
Query: 310 TKQQIRYILQMRGMSDKSLRLVLSTFSNIREELGHLQNDMTSLE----------NDKMRL 359
+ +R L++ + + R V+ I + + Q +L+ ND +RL
Sbjct: 1559 ESKILRVQLELSQVKSELDRKVIEKDEEIEQLKRNSQRAAEALQSVLDAEIRSRNDALRL 1618
Query: 360 EK----DLSFKDTQLKEYEELLASVRANNHQQQQGLQDSSSKCQALEENNLSLRHTLSDM 415
+K DL+ + QL +A + + Q L+DS +N L+ L+ +
Sbjct: 1619 KKKMEGDLNEMEIQLGHSNRQMAETQKHLRTVQGQLKDSQLHLDDALRSNEDLKEQLAIV 1678
Query: 416 EYR----LKELEYCKRNLEQENQNLRMQVSE 442
E R L+ELE K LEQ + R+ E
Sbjct: 1679 ERRNGLLLEELEEMKVALEQTERTRRLSEQE 1709
Score = 32.7 bits (73), Expect = 0.96
Identities = 36/155 (23%), Positives = 68/155 (43%), Gaps = 25/155 (16%)
Query: 393 DSSSKCQALEENNLSLRHTLSDMEYRLKELEYCKRNLEQENQNLRMQV----------SE 442
++ + ++E+ + L+ E R KELE +L QE +L++QV E
Sbjct: 848 EAEKEMATMKEDFERTKEELARSEARRKELEEKMVSLLQEKNDLQLQVQSETENLMDAEE 907
Query: 443 TCTG-----PMLQAKMDEIGNHYTEMVKNLRMEKDREI-CRLRSQLNQYHKDVSKREGSC 496
C G +L+AK+ E+ TE R+E++ E+ L ++ S +
Sbjct: 908 RCEGLIKSKILLEAKVKEL----TE-----RLEEEEEMNSELVAKKRNLEDKCSSLKRDI 958
Query: 497 SDFQFKLHELTSLLEEKDSLIKRQSEELSKLRQEI 531
D + L ++ ++ +K SEE++ L + I
Sbjct: 959 DDLELTLTKVEKEKHATENKVKNLSEEMTALEENI 993
>gi|190341068 forkhead-associated (FHA) phosphopeptide binding
domain 1 [Homo sapiens]
Length = 1412
Score = 52.0 bits (123), Expect = 2e-06
Identities = 37/166 (22%), Positives = 84/166 (50%), Gaps = 13/166 (7%)
Query: 329 RLVLSTFSNIREELGHLQNDMTSLENDKM-------RLEKDLSFKDTQLKEYEELLASVR 381
+++ T S E+ L+N+ +L+ D L+KD+ KD Q+++ +E ++ ++
Sbjct: 315 KVLCQTLSERNSEITSLKNEGENLKRDNAITSGMVSSLQKDILAKDEQVQQLKEEVSHLK 374
Query: 382 ANNHQQQQGLQDSSSKCQALEENNLSLRHTLSDMEYRLKELEYCK---RNLEQENQNLRM 438
+ N + L+ S+C L+E E + KEL+ CK +++E+E + LR
Sbjct: 375 SQNKDKDHQLEALGSRCSVLKEELKQEDAHRELREAQEKELKLCKTQIQDMEKEMKKLRA 434
Query: 439 QVSETCTGPMLQAKMDEIGNHYTEMVKNLRMEKDREICRLRSQLNQ 484
++ ++CT Q+ + +++ + L+ + R++ +L+ N+
Sbjct: 435 ELRKSCTE---QSVISRTLREKSKVEEKLQEDSRRKLLQLQEMGNR 477
Score = 37.4 bits (85), Expect = 0.039
Identities = 38/130 (29%), Positives = 59/130 (45%), Gaps = 11/130 (8%)
Query: 412 LSDMEYRLKELEYCKRNLEQENQNLRMQVSETCTGPMLQAKMDEIGNHYTEMVKNLRMEK 471
LSD E K + NL+ E L +VSET T + ++ + E + K
Sbjct: 240 LSDYEIESKYKDVIIANLQNEVAELSQKVSETTTSRQNEKEISQKCQVLDEDID----AK 295
Query: 472 DREICRLRSQLNQYHKDVSKREGSCSDFQFKLHELTSLLEEKDSLIKRQ----SEELSKL 527
+EI L+SQ++ K SK C + E+TSL E ++L KR S +S L
Sbjct: 296 QKEIQSLKSQISALQKGYSK--VLCQTLSERNSEITSLKNEGENL-KRDNAITSGMVSSL 352
Query: 528 RQEIYSSHNQ 537
+++I + Q
Sbjct: 353 QKDILAKDEQ 362
Score = 36.6 bits (83), Expect = 0.066
Identities = 35/196 (17%), Positives = 91/196 (46%), Gaps = 19/196 (9%)
Query: 345 LQNDMTSLENDKMRLEKDLSFKDTQLKEYEELLASVRANNHQQQQGLQDSSSKCQALEEN 404
L + LE K ++ + +L ++++ +++ Q+ G ++ + +E
Sbjct: 876 LNETLAELETTKTKM----IMVEERLILQQKMVKALQDEQESQRHGFEE---EIMEYKEQ 928
Query: 405 NLSLRHTLSDMEYRLKELEYCKRNLEQENQNLR--------MQVSETCTGPMLQAKMDEI 456
T+ +E +L+++ + +E E L+ + + PM ++ ++
Sbjct: 929 IKQHAQTIVSLEEKLQKVTQHHKKIEGEIATLKDNDPAPKEERPQDPLVAPMTESSAKDM 988
Query: 457 GNHYTEMVKNLRMEKDREICRLRSQLNQYHKDVSKREGSCSDFQFKLHELTSL-LEEKDS 515
Y ++ +L + +EI + + + KD+++ SD + +L+E + LE+
Sbjct: 989 A--YEHLIDDL-LAAQKEILSQQEVIMKLRKDLTEAHSRMSDLRGELNEKQKMELEQNVV 1045
Query: 516 LIKRQSEELSKLRQEI 531
L+++QS+ELS L++++
Sbjct: 1046 LVQQQSKELSVLKEKM 1061
>gi|46049114 M-phase phosphoprotein 1 [Homo sapiens]
Length = 1780
Score = 52.0 bits (123), Expect = 2e-06
Identities = 57/250 (22%), Positives = 116/250 (46%), Gaps = 41/250 (16%)
Query: 294 ESEDIESLIPKGLSEFTKQQIRYILQMRGMSDKSLRLVLSTFSNIREELGHLQNDMTSLE 353
E E I + + L EF + + + ++ K L+L +EE+ L N++ ++
Sbjct: 1149 EKESIILKLERNLKEFQEHLQDSVKNTKDLNVKELKL--------KEEITQLTNNLQDMK 1200
Query: 354 NDKMRLEKDLSFKDTQLKEYEELLASVRANNHQQQQGLQDSSSKCQALEENNLSLRHTLS 413
+ E++ ++T +E E+L + A++ + Q D K EE+ L+ L+
Sbjct: 1201 HLLQLKEEE---EETNRQETEKLKEELSASSARTQNLKADLQRK----EEDYADLKEKLT 1253
Query: 414 DMEYRLKELEYCKRNLEQENQNLRMQVSETCTGPMLQAKMDEIGNHYTEMVKNLRMEKDR 473
D + ++K+++ + E++ LR++++E L+ K ++ + L M K R
Sbjct: 1254 DAKKQIKQVQKEVSVMRDEDKLLRIKINE------LEKKKNQCS-------QELDM-KQR 1299
Query: 474 EICRLRSQLN---------QYH---KDVSKREGSCSDFQFKLHELTSLLEEKDSLIKRQS 521
I +L+ QLN QY KD++ +E D + L E E+D +++ +
Sbjct: 1300 TIQQLKEQLNNQKVEEAIQQYERACKDLNVKEKIIEDMRMTLEEQEQTQVEQDQVLEAKL 1359
Query: 522 EELSKLRQEI 531
EE+ +L E+
Sbjct: 1360 EEVERLATEL 1369
Score = 38.9 bits (89), Expect = 0.013
Identities = 44/196 (22%), Positives = 80/196 (40%), Gaps = 24/196 (12%)
Query: 350 TSLENDKMRLEKDLSFKDTQLKEYEELLASVRANNHQQQQGLQDSSSKCQALEENNLSLR 409
T LE K+ + L E E ++ + N + Q+ LQDS + L L L+
Sbjct: 1128 TILETQKVECSHSAKLEQDIL-EKESIILKLERNLKEFQEHLQDSVKNTKDLNVKELKLK 1186
Query: 410 -------HTLSDMEYRLKELEYCKRNLEQENQNLRMQVSETCTGPM-LQAKMDEIGNHYT 461
+ L DM++ L+ E + QE + L+ ++S + L+A + Y
Sbjct: 1187 EEITQLTNNLQDMKHLLQLKEEEEETNRQETEKLKEELSASSARTQNLKADLQRKEEDYA 1246
Query: 462 EMVKNLRMEKDREICRLRSQLNQYHKDVSKREGSCSDFQFKLHEL-------TSLLEEKD 514
++ + L K Q+ Q K+VS + K++EL + L+ K
Sbjct: 1247 DLKEKLTDAK--------KQIKQVQKEVSVMRDEDKLLRIKINELEKKKNQCSQELDMKQ 1298
Query: 515 SLIKRQSEELSKLRQE 530
I++ E+L+ + E
Sbjct: 1299 RTIQQLKEQLNNQKVE 1314
Score = 33.5 bits (75), Expect = 0.56
Identities = 54/270 (20%), Positives = 111/270 (41%), Gaps = 53/270 (19%)
Query: 307 SEFTKQQIRYILQMRGMSDKS--LRLVLSTFSN-----------IREELGHLQNDMTSLE 353
SE + I I +R + + + LR L T N + +++ H Q +++ E
Sbjct: 824 SEEVRPNIAEIEDIRVLQENNEGLRAFLLTIENELKNEKEEKAELNKQIVHFQQELSLSE 883
Query: 354 NDKMRLEKDLSFKDTQLKEYEELLASVRANNHQQQQGLQDSSSKCQALEE---NNLS--- 407
+ L K++ + L ++ N +Q++ + S++ + NN+S
Sbjct: 884 KKNLTLSKEVQQIQSNYDIAIAELHVQKSKNQEQEEKIMKLSNEIETATRSITNNVSQIK 943
Query: 408 LRHTLSDMEYRLKELEYCKRNLEQENQNLRMQVSETCTGPMLQAKMDEIGNHY--TEMVK 465
L HT D L+ L+ + + NLR + + + ++D +GN Y ++ VK
Sbjct: 944 LMHTKID---ELRTLDSVSQISNIDLLNLRDLSNGSEEDNLPNTQLDLLGNDYLVSKQVK 1000
Query: 466 NLRM-----------------EKDREICRLRS----QLNQYHKDVSKREGSCSDFQFKLH 504
R+ E+ +EI + S Q+ + + + K + ++ + +
Sbjct: 1001 EYRIQEPNRENSFHSSIEAIWEECKEIVKASSKKSHQIEELEQQIEKLQAEVKGYKDENN 1060
Query: 505 ELTS--------LLEEKDSLIKRQSEELSK 526
L LL+EK++LI++ EEL +
Sbjct: 1061 RLKEKEHKNQDDLLKEKETLIQQLKEELQE 1090
>gi|112420968 coiled-coil domain containing 158 [Homo sapiens]
Length = 1113
Score = 51.6 bits (122), Expect = 2e-06
Identities = 68/304 (22%), Positives = 126/304 (41%), Gaps = 42/304 (13%)
Query: 307 SEFTKQQIRYILQMRGMSDKSLRLVLSTFSNIREELGHLQNDMTSLENDKMRLEKDLSFK 366
+ T +R L R M + L +L + E G ++ M +++ LEK +S
Sbjct: 410 NSITIDHLRRELDNRNMEVQRLEALLKALKS--ECQGQMERQMAAIQGKNESLEK-VSSL 466
Query: 367 DTQLKEYEELLASVRANNHQQQQGLQDSS-----------SKCQALEENNLSLRHTLSDM 415
QL+ +E+L V ++ L+ S K +A+E N + S +
Sbjct: 467 TAQLESTKEMLRKVVEELTAKKMTLESSERTISDLTTSLQEKERAIEATNAEITKLRSRV 526
Query: 416 EYRLKELEYCK------RNLEQENQNLRMQVSETCTGPMLQAKMDEIGNHYTEMVKNLRM 469
+ +L+EL++ K RN++ E + L++Q++E + K+ EI E + L
Sbjct: 527 DLKLQELQHLKNEGDHLRNVQTECEALKLQMTE-------KDKVIEILRQQIENMTQLVG 579
Query: 470 EKDREICRLRSQLNQYHKDVSKREGSCSDFQFKLHELTSLLEEKDSLIKRQSEELSKLRQ 529
+ R ++ + Q K+++ R + +L EL L ++KD+ I+ +S L
Sbjct: 580 QHGRTAGAMQVEKAQLEKEINDR-------RMELKELKILKDKKDAKIRELEARVSDLEL 632
Query: 530 EIYSSHNQPSTGGRTTITTKKYR--------TQYPILGLLYDDYEYIPPGSETQTIVIEK 581
E N S R K+ R T L L ++YE + ++ +E
Sbjct: 633 EKVKLVNAGSERLRAVKDIKQERDQLLNEVKTSRSELNNLSEEYEVLKRNFRNKSEEMEM 692
Query: 582 TEDK 585
T +K
Sbjct: 693 TTNK 696
Score = 39.7 bits (91), Expect = 0.008
Identities = 59/283 (20%), Positives = 113/283 (39%), Gaps = 44/283 (15%)
Query: 266 RKNTDLYHCLLEHLQRIGGSKQDFESTDESEDIESLIPKGLSEFTKQQIRYILQMRGMSD 325
R DL L+HL+ G ++ ++ E+ ++ + E +QQI + Q+ G
Sbjct: 523 RSRVDLKLQELQHLKNEGDHLRNVQTECEALKLQMTEKDKVIEILRQQIENMTQLVGQHG 582
Query: 326 KSLRLVLSTFSNIREELGHLQNDMTSL-----ENDKMRLEKDLSFKDTQLKEYE------ 374
++ + + + +E+ + ++ L + D E + D +L++ +
Sbjct: 583 RTAGAMQVEKAQLEKEINDRRMELKELKILKDKKDAKIRELEARVSDLELEKVKLVNAGS 642
Query: 375 ELLASVRANNHQQQQGLQDSSSKCQALEENNLSLRHTLSDMEYRLKELEYCKRNLEQENQ 434
E L +V+ ++ Q L + K E NNLS + + +R K E +E
Sbjct: 643 ERLRAVKDIKQERDQLLNE--VKTSRSELNNLSEEYEVLKRNFRNKSEE-----MEMTTN 695
Query: 435 NLRMQVSETCTGPMLQAKMDEIGNHYTEM------VKNLRMEKDREICRLRSQLNQYHKD 488
L+MQ+ Q+++++ N M + M ++I R Q++
Sbjct: 696 KLKMQLKSA------QSELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDALQ-- 747
Query: 489 VSKREGSCSDFQFKLHELTSLLEEKDSLIKRQSEELSKLRQEI 531
S QF +T+ +EK L EE SKL QE+
Sbjct: 748 --------SKIQFLEEAMTNANKEKHFL----KEEKSKLSQEL 778
Score = 37.4 bits (85), Expect = 0.039
Identities = 49/230 (21%), Positives = 100/230 (43%), Gaps = 33/230 (14%)
Query: 318 LQMRGMSDKSLRLVLSTFSNIREELGHLQNDMTSLENDKMRLEKDLSFKDTQLKE----- 372
+ MR +SD ST S +R EL + E+ LEK L +++L E
Sbjct: 314 MYMRQLSDLE-----STVSQLRSELREAKR---MYEDKTEELEKQLVLANSELTEARTER 365
Query: 373 ---------YEELLASVRANNHQQQQGLQDSSSKCQALEENNLSLRHTLSDMEYRLKELE 423
++ L + A+ H++++ L + + L + + T+ + +EL+
Sbjct: 366 DQFSQESGNLDDQLQKLLADLHKREKELSLEKEQNKRLWDRDTGNSITIDHLR---RELD 422
Query: 424 YCKRNLE-QENQNLRMQVSETCTGPMLQAKMDEIG-NHYTEMVKNLRMEKDREICRLRSQ 481
RN+E Q + L + C G M + G N E V +L + + +
Sbjct: 423 --NRNMEVQRLEALLKALKSECQGQMERQMAAIQGKNESLEKVSSLTAQLEST----KEM 476
Query: 482 LNQYHKDVSKREGSCSDFQFKLHELTSLLEEKDSLIKRQSEELSKLRQEI 531
L + ++++ ++ + + + +LT+ L+EK+ I+ + E++KLR +
Sbjct: 477 LRKVVEELTAKKMTLESSERTISDLTTSLQEKERAIEATNAEITKLRSRV 526
Score = 34.7 bits (78), Expect = 0.25
Identities = 68/329 (20%), Positives = 127/329 (38%), Gaps = 65/329 (19%)
Query: 244 IQDDGPEKLDP----RYFGELLADLSRKNTDLYHCLLEHLQRIGGSKQDFESTDESEDIE 299
++ D P K+ P +F +L + S + DL L E + KQ F D++
Sbjct: 59 VELDSPRKIIPSPGKEHFERVLEEYSHQVKDLQRRLNESNEL--HEKQKFYLRQSVIDLQ 116
Query: 300 SLIPKGLSEFTKQQIRYILQMRGMSDKSLRLVLSTFSNIREELGHLQNDMTSLENDKMRL 359
+ + + + + + I + S + LR LQN + LE K
Sbjct: 117 TKLQE--MQMERDAMADIRRRESQSQEDLR-------------NQLQNTVHELEAAKCLK 161
Query: 360 EKDLSFKDTQLKEYEELLASVRANNHQQQQGLQD---SSSK--CQALEENNLSLRHTLSD 414
E L +TQ+++ +++ S + + L D +S K C+ + L R S
Sbjct: 162 EDMLKDSNTQIEQLRKMMLSHEGVLQEIRSILVDFEEASGKKICEHDSMSTLHFRSLGSA 221
Query: 415 MEYRLKELE----YCKRNLEQENQNLRMQVSETCTGPMLQAKMDEIGNHYTEMVKNLRME 470
+ L+EL+ Y K + L SE+ Q K++ + + + ++ L E
Sbjct: 222 ISKILRELDTEISYLKGRIFPVEDQLEALKSES------QNKIELLLQQHQDRIEQLISE 275
Query: 471 KDREICRL-------------------------RSQLNQYHKDVSKREGSCSDFQFKLHE 505
+ EI L R+Q + Y + +S E + S + +L E
Sbjct: 276 HEVEITGLTEKASSARSQANSIQSQMEIIQEQARNQNSMYMRQLSDLESTVSQLRSELRE 335
Query: 506 LTSLLEEKDSLIKRQ----SEELSKLRQE 530
+ E+K +++Q + EL++ R E
Sbjct: 336 AKRMYEDKTEELEKQLVLANSELTEARTE 364
>gi|58530840 desmoplakin isoform I [Homo sapiens]
Length = 2871
Score = 51.2 bits (121), Expect = 3e-06
Identities = 77/312 (24%), Positives = 128/312 (41%), Gaps = 59/312 (18%)
Query: 273 HCLLEHLQRI--GGSKQDFESTDESEDIESLIPKGLSEFTKQQIRYILQMRGMSDKSLRL 330
H EH Q+ S+ ES E E ++SL TK+ + M ++ LR
Sbjct: 1679 HLRNEHFQKAIEDKSRSLNESKIEIERLQSLT----ENLTKEHL--------MLEEELR- 1725
Query: 331 VLSTFSNIREELGHLQNDMTSLENDK----MRLEKDLSFKDTQLKEYEELLASV---RAN 383
N+R E L+ + ++DK + L L + + E + L+ + R N
Sbjct: 1726 ------NLRLEYDDLRRGRSEADSDKNATILELRSQLQISNNRTLELQGLINDLQREREN 1779
Query: 384 NHQ-----QQQGL------QDSSSKCQALEENNLSLRHTLSDMEY------RLK-ELEYC 425
Q Q+Q L Q+S ++C + + SL + +E RL+ EL
Sbjct: 1780 LRQEIEKFQKQALEASNRIQESKNQCTQVVQERESLLVKIKVLEQDKARLQRLEDELNRA 1839
Query: 426 KRNLEQENQNLRMQVSETCTGPMLQAKMDEIGNHYT---EMVKNLRMEKD---REICRLR 479
K LE E R++ C +Q +++ Y+ E ++ + E++ RE LR
Sbjct: 1840 KSTLEAET---RVKQRLECEKQQIQNDLNQWKTQYSRKEEAIRKIESEREKSEREKNSLR 1896
Query: 480 SQLNQYHKDVSKREGSCS-DFQFKLHELTSLLEEKDSLIKRQSEELSKLRQEIYSSHNQP 538
S++ + ++ + E C + E S LE + S R E+ KLRQ Y SH +
Sbjct: 1897 SEIERLQAEIKRIEERCRRKLEDSTRETQSQLETERS---RYQREIDKLRQRPYGSHRET 1953
Query: 539 STGGRTTITTKK 550
T T+ T K
Sbjct: 1954 QTECEWTVDTSK 1965
Score = 46.2 bits (108), Expect = 8e-05
Identities = 40/198 (20%), Positives = 91/198 (45%), Gaps = 10/198 (5%)
Query: 337 NIREELGHLQNDMTSLENDKMRLEKDLSFKDTQLKEYEELLASVRANNHQQQQGLQDSSS 396
++ EE+ L+N +T + R+E+D+ + E + + Q Q + S
Sbjct: 1404 SLSEEIKRLKNTLTQTTENLRRVEEDIQQQKATGSEVSQRKQQLEVELRQVTQMRTEESV 1463
Query: 397 KCQALEENNLSLRHTLSDMEYRLKELEYCKRNLEQENQNLRMQVSETCTGPMLQAKMDEI 456
+ + SL ++ + KE+E K+ +++E + + E +Q + +
Sbjct: 1464 RYKQ------SLDDAAKTIQDKNKEIERLKQLIDKETNDRKCLEDENARLQRVQYDLQKA 1517
Query: 457 GNHYTEMVKNLRMEKDREICRLRSQLNQYHKDVSKREGSCSDFQFKLHEL---TSLLEEK 513
+ TE + L+++ ++E+ RLR + ++ + ++ + FQ L EL +EE+
Sbjct: 1518 NSSATETINKLKVQ-EQELTRLRIDYERVSQERTVKDQDITRFQNSLKELQLQKQKVEEE 1576
Query: 514 DSLIKRQSEELSKLRQEI 531
+ +KR + E S R+++
Sbjct: 1577 LNRLKRTASEDSCKRKKL 1594
Score = 41.2 bits (95), Expect = 0.003
Identities = 47/218 (21%), Positives = 93/218 (42%), Gaps = 34/218 (15%)
Query: 354 NDKMRLEKDLSFKDTQLKEYEELLASVRANNHQQQQGLQDSSSKCQALEENNLSLRHTLS 413
++ ++ +DL K+T+++ EE L R N ++ +K + L++N + S
Sbjct: 1018 SEMLKSLEDLKLKNTKIEVLEEELRLARDAN-------SENCNKNKFLDQNLQKYQAECS 1070
Query: 414 DMEYRLKELEYCKRNLEQENQNLRMQVSETCTGPMLQAKMDEIGNHYTEMVKNLRMEKDR 473
+ +L LE KR E + ++ + + + C G ++ E+ T + + EK R
Sbjct: 1071 QFKAKLASLEELKRQAELDGKSAKQNL-DKCYG-----QIKELNEKITRLTYEIEDEKRR 1124
Query: 474 EIC---RLRSQLNQYHKDVSKR--------------EGSCSDFQFKLHELTSLLEEKDSL 516
R Q N Y + R E + + ++++ L LL+E+ +
Sbjct: 1125 RKSVEDRFDQQKNDYDQLQKARQCEKENLGWQKLESEKAIKEKEYEIERLRVLLQEEGTR 1184
Query: 517 IKRQSEELSKLR----QEIYSSHNQPSTGGRTTITTKK 550
+ EL+K+R +E+ + N+ T T TT K
Sbjct: 1185 KREYENELAKVRNHYNEEMSNLRNKYETEINITKTTIK 1222
Score = 37.7 bits (86), Expect = 0.030
Identities = 38/217 (17%), Positives = 89/217 (41%), Gaps = 17/217 (7%)
Query: 312 QQIRYILQMRGMSDKSLRLVLSTFSNIREELGHLQNDMTSLENDKMRLEKDLSFKDTQLK 371
Q+++Y LQ ++ S ++ +EL L+ D + ++ ++D++ LK
Sbjct: 1508 QRVQYDLQK---ANSSATETINKLKVQEQELTRLRIDYERVSQERTVKDQDITRFQNSLK 1564
Query: 372 EYEELLASVRANNHQQQQGLQDSSSKCQALEENNLSLRHTLSDMEYRLKELEYCKRNLEQ 431
E + V ++ ++ + S K + LEE +R +L + ++ L + LEQ
Sbjct: 1565 ELQLQKQKVEEELNRLKRTASEDSCKRKKLEEELEGMRRSLKEQAIKITNL---TQQLEQ 1621
Query: 432 ENQNLRMQVSETCTGPMLQAKMDEIGNHYTEMVKNLRMEKDREICRLRSQLNQYHKDVSK 491
+ + + + L+ + D + H E + E+ RL S++ + + +
Sbjct: 1622 AS------IVKKRSEDDLRQQRDVLDGHLRE-----KQRTQEELRRLSSEVEALRRQLLQ 1670
Query: 492 REGSCSDFQFKLHELTSLLEEKDSLIKRQSEELSKLR 528
+ S + +E+K + E+ +L+
Sbjct: 1671 EQESVKQAHLRNEHFQKAIEDKSRSLNESKIEIERLQ 1707
Score = 37.0 bits (84), Expect = 0.051
Identities = 49/228 (21%), Positives = 95/228 (41%), Gaps = 29/228 (12%)
Query: 325 DKSLRLVLSTFSNIREELGHLQNDMTSLENDKMRLEKDLSFKDTQLKEYEELLASVR--- 381
D++L+ + S + +L L+ E D +++L Q+KE E + +
Sbjct: 1059 DQNLQKYQAECSQFKAKLASLEELKRQAELDGKSAKQNLDKCYGQIKELNEKITRLTYEI 1118
Query: 382 ----------ANNHQQQQGLQDSSSKCQALEENNLSLRHTLSDMEYRLKELEYCKRNLEQ 431
+ QQ+ D K + E+ NL + S E +KE EY
Sbjct: 1119 EDEKRRRKSVEDRFDQQKNDYDQLQKARQCEKENLGWQKLES--EKAIKEKEY------- 1169
Query: 432 ENQNLRMQVSETCTGPM-LQAKMDEIGNHYTEMVKNLRMEKDREICRLRSQLNQYHKDVS 490
E + LR+ + E T + ++ ++ NHY E + NLR + + EI ++ + K++S
Sbjct: 1170 EIERLRVLLQEEGTRKREYENELAKVRNHYNEEMSNLRNKYETEINITKTTI----KEIS 1225
Query: 491 -KREGSCSDFQFKLHELTSLLEE-KDSLIKRQSEELSKLRQEIYSSHN 536
++E + + +L L+ + KD +++ L Q + N
Sbjct: 1226 MQKEDDSKNLRNQLDRLSRENRDLKDEIVRLNDSILQATEQRRRAEEN 1273
Score = 30.0 bits (66), Expect = 6.2
Identities = 42/204 (20%), Positives = 85/204 (41%), Gaps = 28/204 (13%)
Query: 336 SNIREELGHLQNDM--------TSLENDKMRLEKDLSFKDTQLKEYEELLASVRANNHQQ 387
+N EE+ L+N T++ M+ E+D S Q+ S+ +
Sbjct: 1353 NNYDEEIISLKNQFETEINITKTTIHQLTMQKEEDTSGYRAQIDNLTRENRSLSEEIKRL 1412
Query: 388 QQGLQDSSSKCQALEENNLSLRHTLSDMEYRLKELEYCKRNLEQENQNLRMQVSETCTGP 447
+ L ++ + +EE+ + T S++ R ++LE R QV++ T
Sbjct: 1413 KNTLTQTTENLRRVEEDIQQQKATGSEVSQRKQQLEVELR-----------QVTQMRTEE 1461
Query: 448 MLQAKMDEIGNHYTEMVKNLRMEKDREICRLRSQLNQYHKD---VSKREGSCSDFQFKLH 504
++ K + K ++ +K++EI RL+ +++ D + Q+ L
Sbjct: 1462 SVRYKQS-----LDDAAKTIQ-DKNKEIERLKQLIDKETNDRKCLEDENARLQRVQYDLQ 1515
Query: 505 ELTSLLEEKDSLIKRQSEELSKLR 528
+ S E + +K Q +EL++LR
Sbjct: 1516 KANSSATETINKLKVQEQELTRLR 1539
>gi|41872583 Rho-associated, coiled-coil containing protein kinase 2
[Homo sapiens]
Length = 1388
Score = 51.2 bits (121), Expect = 3e-06
Identities = 56/269 (20%), Positives = 123/269 (45%), Gaps = 30/269 (11%)
Query: 295 SEDIESLIPKGLSEFTKQQI-RYILQMRGMSDKSLRLVLSTFSNIREELGHLQNDMTSLE 353
+ED+ +L K E K+ + + L+M+ +L++ + +++E HL +LE
Sbjct: 786 NEDVRNLTLKIEQETQKRCLTQNDLKMQTQQVNTLKM---SEKQLKQENNHLMEMKMNLE 842
Query: 354 NDKMRLEKDLSFKDTQLKEYEELLASVRANNHQQQQGLQDSSSKCQALEENNLSLRHTLS 413
L K+ D Q+KE ++ L + + + + +++ +C+ E+ L
Sbjct: 843 KQNAELRKERQDADGQMKELQDQLEAEQYFSTLYKTQVRELKEECE--EKTKLG------ 894
Query: 414 DMEYRLKELEYCKRNLEQENQNLRMQVSETCTGPMLQAKMDEIGNHYTE-MVKNLRMEKD 472
KEL+ K+ L+ E +L Q+ T T +A +++ E +L EK
Sbjct: 895 ------KELQQKKQELQDERDSLAAQLEITLT----KADSEQLARSIAEEQYSDLEKEKI 944
Query: 473 REICRLRSQLNQYHKDVSKREGSCSDFQFKLHELTS----LLEEKDSL---IKRQSEELS 525
+ ++ + ++ +++++++ + + + LTS L EK+ L +K E+LS
Sbjct: 945 MKELEIKEMMARHKQELTEKDATIASLEETNRTLTSDVANLANEKEELNNKLKDVQEQLS 1004
Query: 526 KLRQEIYSSHNQPSTGGRTTITTKKYRTQ 554
+L+ E S+ + + +T + +TQ
Sbjct: 1005 RLKDEEISAAAIKAQFEKQLLTERTLKTQ 1033
Score = 43.5 bits (101), Expect = 5e-04
Identities = 48/206 (23%), Positives = 97/206 (47%), Gaps = 30/206 (14%)
Query: 335 FSNIREELGHLQNDMTSLENDKMRLEKDLSFKDTQLKEYEELLASVRANNHQQQQGLQDS 394
F+ RE L L + + E D ++ S K+ + +E ++ L ++ + + Q ++
Sbjct: 413 FTYYRENL-LLSDSPSCRETDSIQ-----SRKNEESQEIQKKLYTLEEHLSNEMQAKEEL 466
Query: 395 SSKCQALEENNLSLRHTLSDMEYRL---KELEYCKRNLEQENQNLRMQVSETCTGPMLQA 451
KC+++ N L T ++E + K +E R LE+E L+ + +E Q
Sbjct: 467 EQKCKSV---NTRLEKTAKELEEEITLRKSVESALRQLEREKALLQHKNAE------YQR 517
Query: 452 KMDEIGNHYTEMVKNLRMEKDREICRLRSQLNQYHKDVSKREGSCSDFQFKLHELTSLLE 511
K D H + +NL + ++ L+ QL +D+ KR + K+++L L+
Sbjct: 518 KAD----HEADKKRNL----ENDVNSLKDQL----EDLKKRNQNSQISTEKVNQLQRQLD 565
Query: 512 EKDSLIKRQSEELSKLRQEIYSSHNQ 537
E ++L++ +S+ ++LR+ S Q
Sbjct: 566 ETNALLRTESDTAARLRKTQAESSKQ 591
Score = 39.3 bits (90), Expect = 0.010
Identities = 52/248 (20%), Positives = 110/248 (44%), Gaps = 43/248 (17%)
Query: 293 DESEDIESLIPKGLSEFTKQQIRYILQMRGMSDKSLRLVL---STFSNIREELGHLQNDM 349
D + S+ + S+ K++I L+++ M + + + +T +++ E L +D+
Sbjct: 923 DSEQLARSIAEEQYSDLEKEKIMKELEIKEMMARHKQELTEKDATIASLEETNRTLTSDV 982
Query: 350 TSLENDKMRLE---KDLSFKDTQLKEYEELLASVRANNHQQQQGLQDSSSKCQALEENNL 406
+L N+K L KD+ + ++LK+ E A+++A +Q L + + K QA+ +
Sbjct: 983 ANLANEKEELNNKLKDVQEQLSRLKDEEISAAAIKAQFEKQL--LTERTLKTQAVNK--- 1037
Query: 407 SLRHTLSDMEYRLKELEYCKRNLEQENQNLRMQVSETCTGPMLQAKMDEIGNHYTEMVKN 466
L ++ E + + R E+EN+ L M+
Sbjct: 1038 -LAEIMNRKEPVKRGNDTDVRRKEKENRKLHME--------------------------- 1069
Query: 467 LRMEKDREICRLRSQLNQYHKDVSKREGSCSDFQFKLHELTSLLEEKDSLIKRQSEELSK 526
++ +RE +L Q+ +Y K++++ + ++ EL L+ KDS I++ +L
Sbjct: 1070 --LKSERE--KLTQQMIKYQKELNEMQAQIAEESQIRIELQMTLDSKDSDIEQLRSQLQA 1125
Query: 527 LRQEIYSS 534
L + SS
Sbjct: 1126 LHIGLDSS 1133
Score = 33.5 bits (75), Expect = 0.56
Identities = 56/302 (18%), Positives = 123/302 (40%), Gaps = 49/302 (16%)
Query: 251 KLDPRYFGELLADLSRKNTDLYHCLLEHLQRIGGSKQDFES---------TDESEDIESL 301
+L+ R E DL ++ +++ + L+ I S + E+ D+++ ES
Sbjct: 666 ELEKRQLQERFTDLEKEKSNMEIDMTYQLKVIQQSLEQEEAEHKATKARLADKNKIYES- 724
Query: 302 IPKGLSEFTKQQIRYILQMRGMSDKSLRLVLSTFSNIREELGHLQNDMTSLENDKMRLEK 361
I + SE K+ + +L+ R + K +EN + EK
Sbjct: 725 IEEAKSEAMKEMEKKLLEERTLKQK-------------------------VENLLLEAEK 759
Query: 362 DLSFKDTQLKEYEELLASVRANNHQQQQGLQDSSSKCQALEENNLSLRHTLSDMEYRLKE 421
S D LK+ ++ + + + +++ + K + + ++ L ++
Sbjct: 760 RCSLLDCDLKQSQQKINELLKQKDVLNEDVRNLTLKIEQETQKRCLTQNDLKMQTQQVNT 819
Query: 422 LEYCKRNLEQENQNL-RMQVSETCTGPMLQAKMDEIGNHYTEMVKNLRMEKDREICRLRS 480
L+ ++ L+QEN +L M+++ L+ + + E+ L E+ ++
Sbjct: 820 LKMSEKQLKQENNHLMEMKMNLEKQNAELRKERQDADGQMKELQDQLEAEQYFSTL-YKT 878
Query: 481 QLNQYHKDVSKREGSCSDFQFKLHELTSLLEEKDS--------LIKRQSEELSK-LRQEI 531
Q+ + ++ ++ + Q K EL +E+DS L K SE+L++ + +E
Sbjct: 879 QVRELKEECEEKTKLGKELQQKKQELQ---DERDSLAAQLEITLTKADSEQLARSIAEEQ 935
Query: 532 YS 533
YS
Sbjct: 936 YS 937
Score = 32.7 bits (73), Expect = 0.96
Identities = 54/302 (17%), Positives = 125/302 (41%), Gaps = 32/302 (10%)
Query: 261 LADLSRKNTDLYHCLLEHLQRI---GGSKQDFESTDES--EDIESLIPKGL-SEFTKQQI 314
L L R+ L H E+ ++ K++ E+ S + +E L + S+ + +++
Sbjct: 498 LRQLEREKALLQHKNAEYQRKADHEADKKRNLENDVNSLKDQLEDLKKRNQNSQISTEKV 557
Query: 315 RYILQMRGMSDKSLRLVLSTFSNIREELGHLQNDMTSLENDKMRLE-KDLSFKDTQLK-- 371
+ + ++ LR T + +R+ + LE++ L+ K+ + +LK
Sbjct: 558 NQLQRQLDETNALLRTESDTAARLRKTQAESSKQIQQLESNNRDLQDKNCLLETAKLKLE 617
Query: 372 -EYEELLASVRANNHQQQQG---LQDSSSKCQALEENNLSLRHTLSDMEYRLKELEYCKR 427
E+ L +++ + + G + D + LEE+ + + L+ +E ++L+
Sbjct: 618 KEFINLQSALESERRDRTHGSEIINDLQGRICGLEEDLKNGKILLAKVELEKRQLQERFT 677
Query: 428 NLEQENQNLRMQVS------------ETCTGPMLQAKM---DEIGNHYTEMVKNLRMEKD 472
+LE+E N+ + ++ E +A++ ++I E E +
Sbjct: 678 DLEKEKSNMEIDMTYQLKVIQQSLEQEEAEHKATKARLADKNKIYESIEEAKSEAMKEME 737
Query: 473 REICRLRSQLNQYHKDVSKREGSCS----DFQFKLHELTSLLEEKDSLIKRQSEELSKLR 528
+++ R+ + + + E CS D + ++ LL++KD L + K+
Sbjct: 738 KKLLEERTLKQKVENLLLEAEKRCSLLDCDLKQSQQKINELLKQKDVLNEDVRNLTLKIE 797
Query: 529 QE 530
QE
Sbjct: 798 QE 799
>gi|237858621 polyamine modulated factor 1 binding protein 1 isoform
b [Homo sapiens]
Length = 882
Score = 50.8 bits (120), Expect = 3e-06
Identities = 55/249 (22%), Positives = 110/249 (44%), Gaps = 20/249 (8%)
Query: 291 STDESEDIESLIPKGLSEFTKQQIRYILQMRGMSDKSLRLVLSTFS----NIREELGHLQ 346
S++E EDI+ ++ K L E Q ++ + + + K LR+ L S NI +++ L+
Sbjct: 152 SSEECEDIKKIL-KHLQEQKDSQCLHVEEYQNLV-KDLRVELEAVSEQKRNIMKDMMKLE 209
Query: 347 NDMTSLENDKM----RLEKDLSFKDTQLKEYEELLASVRANNHQQQQGLQDSSSKCQALE 402
D+ L + R +KD++ +L+E + + ++ + LQ+ Q LE
Sbjct: 210 LDLHGLREETSAHIERKDKDITILQCRLQELQLEFTETQKLTLKKDKFLQEKDEMLQELE 269
Query: 403 ENNLSLRHTLSDMEYRLKELEYCKRNLEQENQNLRMQVSETCTGPMLQAKMDEIGNHYTE 462
+ ++++L E L++ + LE + + S+ LQA++ ++ N E
Sbjct: 270 KKLTQVQNSLLKKEKELEKQQCMATELEMTVKEAKQDKSKEAECKALQAEVQKLKNSLEE 329
Query: 463 MVKNLRMEKDREI-CRLRSQLNQYHKDVSKREGSCSDFQFKLHELTSLLEEKDSLIKRQS 521
+ R+ + C+ + L H + D Q KL + L ++K I+
Sbjct: 330 AKQQERLAAQQAAQCKEEAALAGCHLE---------DTQRKLQKGLLLDKQKADTIQELQ 380
Query: 522 EELSKLRQE 530
EL L++E
Sbjct: 381 RELQMLQKE 389
Score = 44.3 bits (103), Expect = 3e-04
Identities = 55/262 (20%), Positives = 111/262 (42%), Gaps = 26/262 (9%)
Query: 296 EDIESLIPKGL-----SEFTKQQIRYILQM----RGMSDKSLRLVLSTFSNIREELGHLQ 346
ED + + KGL T Q+++ LQM M++K + EL
Sbjct: 356 EDTQRKLQKGLLLDKQKADTIQELQRELQMLQKESSMAEKEQTSNRKRVEELSLELSEAL 415
Query: 347 NDMTSLENDKMRLEKDLSFKDTQLKEYEELLASVRANNHQQQQGLQDSSSKCQALEENNL 406
+ + + +K +L+K ++ +D ++ + + R + ++QG S KC+ LEE+
Sbjct: 416 RKLENSDKEKRQLQKTVAEQDMKMNDMLD-----RIKHQHREQG----SIKCK-LEEDLQ 465
Query: 407 SLRHTLSDMEYRLKELEYCKRNLEQENQNLRMQVSETCTGPMLQAKMDEIGNHYTEMVKN 466
L D +LK+ + ++ +E E + LR + + + E E +N
Sbjct: 466 EATKLLEDKREQLKKSKEHEKLMEGELEALRQEFKKK------DKTLKENSRKLEEENEN 519
Query: 467 LRMEKDREICRLRSQLNQYHKDVSKREGSCSDFQFKLHELTSLLEEKDSLIKRQSEEL-S 525
LR E +L S LN+Y+ + + + L SL + D ++++ L +
Sbjct: 520 LRAELQCCSTQLESSLNKYNTSQQVIQDLNKEIALQKESLMSLQAQLDKALQKEKHYLQT 579
Query: 526 KLRQEIYSSHNQPSTGGRTTIT 547
+ +E Y + ++ S + +T
Sbjct: 580 TITKEAYDALSRKSAACQDDLT 601
Score = 34.7 bits (78), Expect = 0.25
Identities = 55/308 (17%), Positives = 124/308 (40%), Gaps = 33/308 (10%)
Query: 259 ELLADLSRKNTDLYHCLLEHLQRIGGSKQDFESTDESEDIESLIPKGLSEFTKQQIRYIL 318
E+L +L +K T + + LL+ + + KQ +T+ +E + + + +K+ L
Sbjct: 263 EMLQELEKKLTQVQNSLLKKEKEL--EKQQCMATE----LEMTVKEAKQDKSKEAECKAL 316
Query: 319 QMRGMSDKSL--------RLVLSTFSNIREELGHLQNDMTSLENDKMRLEKDLSFKDTQL 370
Q K+ RL + +EE LE+ + +L+K L +
Sbjct: 317 QAEVQKLKNSLEEAKQQERLAAQQAAQCKEEAALAG---CHLEDTQRKLQKGLLLDKQKA 373
Query: 371 KEYEELLASVRANNHQQQQGLQDSSSKCQALEENNLSLRHTLSDMEYRLKELEYCKRNLE 430
+EL ++ + ++ +S + +EE +L L L +E N +
Sbjct: 374 DTIQELQRELQMLQKESSMAEKEQTSNRKRVEELSLELSEALRKLE-----------NSD 422
Query: 431 QENQNLRMQVSETCTGPMLQAKMDEIGNHYTEMVKNLRMEKDREICRLRSQLNQYHKDVS 490
+E + L+ V+E + +D I + + E +++ + + ++ L + +
Sbjct: 423 KEKRQLQKTVAE--QDMKMNDMLDRIKHQHREQ-GSIKCKLEEDLQEATKLLEDKREQLK 479
Query: 491 KREGSCSDFQFKLHELTSLLEEKDSLIKRQSEELSKLRQEIYSSHNQPSTGGRTTITTKK 550
K + + +L L ++KD +K S +L + + + + ST +++ K
Sbjct: 480 KSKEHEKLMEGELEALRQEFKKKDKTLKENSRKLEEENENLRAELQCCSTQLESSL--NK 537
Query: 551 YRTQYPIL 558
Y T ++
Sbjct: 538 YNTSQQVI 545
Score = 29.6 bits (65), Expect = 8.1
Identities = 33/181 (18%), Positives = 81/181 (44%), Gaps = 14/181 (7%)
Query: 363 LSFKDTQLKEYEELLASVRANNHQQQQGL---QDSSSKCQALEENNLSLRHTLSDMEYRL 419
+S +D ++E LA A ++++ L Q + C A S D++ L
Sbjct: 104 VSQQDDLIQELRNKLACSNALVLEREKALIKLQADFASCTATHRYPPSSSEECEDIKKIL 163
Query: 420 KELEYCKRNLEQENQNLRMQVSETCTGPMLQAKMDEIGNHYTEMVKNLRMEKDREICRLR 479
K L+ ++++Q L ++ + L+ +++ + ++K++ M+ + ++ LR
Sbjct: 164 KHLQE-----QKDSQCLHVEEYQNLVKD-LRVELEAVSEQKRNIMKDM-MKLELDLHGLR 216
Query: 480 SQLNQY----HKDVSKREGSCSDFQFKLHELTSLLEEKDSLIKRQSEELSKLRQEIYSSH 535
+ + + KD++ + + Q + E L +KD ++ + E L +L +++
Sbjct: 217 EETSAHIERKDKDITILQCRLQELQLEFTETQKLTLKKDKFLQEKDEMLQELEKKLTQVQ 276
Query: 536 N 536
N
Sbjct: 277 N 277
>gi|237858619 polyamine modulated factor 1 binding protein 1 isoform
a [Homo sapiens]
Length = 1007
Score = 50.8 bits (120), Expect = 3e-06
Identities = 55/249 (22%), Positives = 110/249 (44%), Gaps = 20/249 (8%)
Query: 291 STDESEDIESLIPKGLSEFTKQQIRYILQMRGMSDKSLRLVLSTFS----NIREELGHLQ 346
S++E EDI+ ++ K L E Q ++ + + + K LR+ L S NI +++ L+
Sbjct: 297 SSEECEDIKKIL-KHLQEQKDSQCLHVEEYQNLV-KDLRVELEAVSEQKRNIMKDMMKLE 354
Query: 347 NDMTSLENDKM----RLEKDLSFKDTQLKEYEELLASVRANNHQQQQGLQDSSSKCQALE 402
D+ L + R +KD++ +L+E + + ++ + LQ+ Q LE
Sbjct: 355 LDLHGLREETSAHIERKDKDITILQCRLQELQLEFTETQKLTLKKDKFLQEKDEMLQELE 414
Query: 403 ENNLSLRHTLSDMEYRLKELEYCKRNLEQENQNLRMQVSETCTGPMLQAKMDEIGNHYTE 462
+ ++++L E L++ + LE + + S+ LQA++ ++ N E
Sbjct: 415 KKLTQVQNSLLKKEKELEKQQCMATELEMTVKEAKQDKSKEAECKALQAEVQKLKNSLEE 474
Query: 463 MVKNLRMEKDREI-CRLRSQLNQYHKDVSKREGSCSDFQFKLHELTSLLEEKDSLIKRQS 521
+ R+ + C+ + L H + D Q KL + L ++K I+
Sbjct: 475 AKQQERLAAQQAAQCKEEAALAGCHLE---------DTQRKLQKGLLLDKQKADTIQELQ 525
Query: 522 EELSKLRQE 530
EL L++E
Sbjct: 526 RELQMLQKE 534
Score = 44.3 bits (103), Expect = 3e-04
Identities = 55/262 (20%), Positives = 111/262 (42%), Gaps = 26/262 (9%)
Query: 296 EDIESLIPKGL-----SEFTKQQIRYILQM----RGMSDKSLRLVLSTFSNIREELGHLQ 346
ED + + KGL T Q+++ LQM M++K + EL
Sbjct: 501 EDTQRKLQKGLLLDKQKADTIQELQRELQMLQKESSMAEKEQTSNRKRVEELSLELSEAL 560
Query: 347 NDMTSLENDKMRLEKDLSFKDTQLKEYEELLASVRANNHQQQQGLQDSSSKCQALEENNL 406
+ + + +K +L+K ++ +D ++ + + R + ++QG S KC+ LEE+
Sbjct: 561 RKLENSDKEKRQLQKTVAEQDMKMNDMLD-----RIKHQHREQG----SIKCK-LEEDLQ 610
Query: 407 SLRHTLSDMEYRLKELEYCKRNLEQENQNLRMQVSETCTGPMLQAKMDEIGNHYTEMVKN 466
L D +LK+ + ++ +E E + LR + + + E E +N
Sbjct: 611 EATKLLEDKREQLKKSKEHEKLMEGELEALRQEFKKK------DKTLKENSRKLEEENEN 664
Query: 467 LRMEKDREICRLRSQLNQYHKDVSKREGSCSDFQFKLHELTSLLEEKDSLIKRQSEEL-S 525
LR E +L S LN+Y+ + + + L SL + D ++++ L +
Sbjct: 665 LRAELQCCSTQLESSLNKYNTSQQVIQDLNKEIALQKESLMSLQAQLDKALQKEKHYLQT 724
Query: 526 KLRQEIYSSHNQPSTGGRTTIT 547
+ +E Y + ++ S + +T
Sbjct: 725 TITKEAYDALSRKSAACQDDLT 746
Score = 34.7 bits (78), Expect = 0.25
Identities = 55/308 (17%), Positives = 124/308 (40%), Gaps = 33/308 (10%)
Query: 259 ELLADLSRKNTDLYHCLLEHLQRIGGSKQDFESTDESEDIESLIPKGLSEFTKQQIRYIL 318
E+L +L +K T + + LL+ + + KQ +T+ +E + + + +K+ L
Sbjct: 408 EMLQELEKKLTQVQNSLLKKEKEL--EKQQCMATE----LEMTVKEAKQDKSKEAECKAL 461
Query: 319 QMRGMSDKSL--------RLVLSTFSNIREELGHLQNDMTSLENDKMRLEKDLSFKDTQL 370
Q K+ RL + +EE LE+ + +L+K L +
Sbjct: 462 QAEVQKLKNSLEEAKQQERLAAQQAAQCKEEAALAG---CHLEDTQRKLQKGLLLDKQKA 518
Query: 371 KEYEELLASVRANNHQQQQGLQDSSSKCQALEENNLSLRHTLSDMEYRLKELEYCKRNLE 430
+EL ++ + ++ +S + +EE +L L L +E N +
Sbjct: 519 DTIQELQRELQMLQKESSMAEKEQTSNRKRVEELSLELSEALRKLE-----------NSD 567
Query: 431 QENQNLRMQVSETCTGPMLQAKMDEIGNHYTEMVKNLRMEKDREICRLRSQLNQYHKDVS 490
+E + L+ V+E + +D I + + E +++ + + ++ L + +
Sbjct: 568 KEKRQLQKTVAE--QDMKMNDMLDRIKHQHREQ-GSIKCKLEEDLQEATKLLEDKREQLK 624
Query: 491 KREGSCSDFQFKLHELTSLLEEKDSLIKRQSEELSKLRQEIYSSHNQPSTGGRTTITTKK 550
K + + +L L ++KD +K S +L + + + + ST +++ K
Sbjct: 625 KSKEHEKLMEGELEALRQEFKKKDKTLKENSRKLEEENENLRAELQCCSTQLESSL--NK 682
Query: 551 YRTQYPIL 558
Y T ++
Sbjct: 683 YNTSQQVI 690
Score = 32.7 bits (73), Expect = 0.96
Identities = 44/213 (20%), Positives = 96/213 (45%), Gaps = 33/213 (15%)
Query: 340 EELGHLQNDMTSLEND-------KMRLEKDLSFKDTQLKEYEELLASVRANNHQQQQGLQ 392
E+L H+ ++ SL+ K +LE+++ + ++K+ L +R + + + +
Sbjct: 750 EKLNHVTSETKSLQQSLTQTQEKKAQLEEEIIAYEERMKKLNTELRKLRGFHQESELEVH 809
Query: 393 DSSSK-----CQALE-----ENNLSLRHTLSDMEYRLKELEYCKRNLEQENQNLRMQVSE 442
K CQ L+ +N+L + L+ E +L+E + + +NL E
Sbjct: 810 AFDKKLEEMSCQVLQWQKQHQNDLKM---LAAKEEQLREFQ---EEMAALKENLLEDDKE 863
Query: 443 TCTGPMLQAKMD--EIGNHYTEMVKNL-RMEKDREIC--RLRSQLNQYHKDVSKREGSCS 497
C P D + +++ NL + K +++ +L +QL + K ++K G
Sbjct: 864 PCCLPQWSVPKDTCRLYRGNDQIMTNLEQWAKQQKVANEKLGNQLREQVKYIAKLSGE-- 921
Query: 498 DFQFKLHELTSLLEEKDSLIKRQSEELSKLRQE 530
+ LH + L++++ +K++ EE K++ E
Sbjct: 922 --KDHLHSVMVHLQQENKKLKKEIEE-KKMKAE 951
Score = 29.6 bits (65), Expect = 8.1
Identities = 33/181 (18%), Positives = 81/181 (44%), Gaps = 14/181 (7%)
Query: 363 LSFKDTQLKEYEELLASVRANNHQQQQGL---QDSSSKCQALEENNLSLRHTLSDMEYRL 419
+S +D ++E LA A ++++ L Q + C A S D++ L
Sbjct: 249 VSQQDDLIQELRNKLACSNALVLEREKALIKLQADFASCTATHRYPPSSSEECEDIKKIL 308
Query: 420 KELEYCKRNLEQENQNLRMQVSETCTGPMLQAKMDEIGNHYTEMVKNLRMEKDREICRLR 479
K L+ ++++Q L ++ + L+ +++ + ++K++ M+ + ++ LR
Sbjct: 309 KHLQE-----QKDSQCLHVEEYQNLVKD-LRVELEAVSEQKRNIMKDM-MKLELDLHGLR 361
Query: 480 SQLNQY----HKDVSKREGSCSDFQFKLHELTSLLEEKDSLIKRQSEELSKLRQEIYSSH 535
+ + + KD++ + + Q + E L +KD ++ + E L +L +++
Sbjct: 362 EETSAHIERKDKDITILQCRLQELQLEFTETQKLTLKKDKFLQEKDEMLQELEKKLTQVQ 421
Query: 536 N 536
N
Sbjct: 422 N 422
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.128 0.370
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,306,020
Number of Sequences: 37866
Number of extensions: 1068930
Number of successful extensions: 5644
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 117
Number of HSP's successfully gapped in prelim test: 544
Number of HSP's that attempted gapping in prelim test: 3902
Number of HSP's gapped (non-prelim): 1787
length of query: 589
length of database: 18,247,518
effective HSP length: 108
effective length of query: 481
effective length of database: 14,157,990
effective search space: 6809993190
effective search space used: 6809993190
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.