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Search of human proteins with 192455698
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|192455698 glutathione peroxidase 8 [Homo sapiens]
(209 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|192455698 glutathione peroxidase 8 [Homo sapiens] 424 e-119
gi|15618997 glutathione peroxidase 7 [Homo sapiens] 206 1e-53
gi|90903240 glutathione peroxidase 4 isoform C precursor [Homo s... 108 2e-24
gi|75709200 glutathione peroxidase 4 isoform A precursor [Homo s... 108 2e-24
gi|90903238 glutathione peroxidase 4 isoform B precursor [Homo s... 94 6e-20
gi|41406084 glutathione peroxidase 1 isoform 1 [Homo sapiens] 86 3e-17
gi|4557629 glutathione peroxidase 5 isoform 1 precursor [Homo sa... 82 3e-16
gi|32967607 glutathione peroxidase 2 [Homo sapiens] 78 6e-15
gi|6006001 glutathione peroxidase 3 precursor [Homo sapiens] 74 9e-14
gi|33186887 glutathione peroxidase 6 [Homo sapiens] 70 1e-12
gi|41406082 glutathione peroxidase 1 isoform 2 [Homo sapiens] 60 2e-09
gi|84043967 REV1-like isoform 2 [Homo sapiens] 32 0.30
gi|7706681 REV1-like isoform 1 [Homo sapiens] 32 0.30
gi|115511057 hypothetical protein LOC256643 [Homo sapiens] 32 0.39
gi|49533617 sterol O-acyltransferase 1 [Homo sapiens] 29 2.5
gi|125628665 hypothetical protein LOC388284 [Homo sapiens] 28 7.3
gi|170784850 SCY1-like 3 isoform 2 [Homo sapiens] 27 9.5
gi|170784842 SCY1-like 3 isoform 1 [Homo sapiens] 27 9.5
gi|24432032 zinc finger protein 503 [Homo sapiens] 27 9.5
gi|6715602 glutathione peroxidase 5 isoform 2 precursor [Homo sa... 27 9.5
>gi|192455698 glutathione peroxidase 8 [Homo sapiens]
Length = 209
Score = 424 bits (1091), Expect = e-119
Identities = 209/209 (100%), Positives = 209/209 (100%)
Query: 1 MEPLAAYPLKCSGPRAKVFAVLLSIVLCTVTLFLLQLKFLKPKINSFYAFEVKDAKGRTV 60
MEPLAAYPLKCSGPRAKVFAVLLSIVLCTVTLFLLQLKFLKPKINSFYAFEVKDAKGRTV
Sbjct: 1 MEPLAAYPLKCSGPRAKVFAVLLSIVLCTVTLFLLQLKFLKPKINSFYAFEVKDAKGRTV 60
Query: 61 SLEKYKGKVSLVVNVASDCQLTDRNYLGLKELHKEFGPSHFSVLAFPCNQFGESEPRPSK 120
SLEKYKGKVSLVVNVASDCQLTDRNYLGLKELHKEFGPSHFSVLAFPCNQFGESEPRPSK
Sbjct: 61 SLEKYKGKVSLVVNVASDCQLTDRNYLGLKELHKEFGPSHFSVLAFPCNQFGESEPRPSK 120
Query: 121 EVESFARKNYGVTFPIFHKIKILGSEGEPAFRFLVDSSKKEPRWNFWKYLVNPEGQVVKF 180
EVESFARKNYGVTFPIFHKIKILGSEGEPAFRFLVDSSKKEPRWNFWKYLVNPEGQVVKF
Sbjct: 121 EVESFARKNYGVTFPIFHKIKILGSEGEPAFRFLVDSSKKEPRWNFWKYLVNPEGQVVKF 180
Query: 181 WKPEEPIEVIRPDIAALVRQVIIKKKEDL 209
WKPEEPIEVIRPDIAALVRQVIIKKKEDL
Sbjct: 181 WKPEEPIEVIRPDIAALVRQVIIKKKEDL 209
>gi|15618997 glutathione peroxidase 7 [Homo sapiens]
Length = 187
Score = 206 bits (523), Expect = 1e-53
Identities = 92/163 (56%), Positives = 124/163 (76%)
Query: 47 FYAFEVKDAKGRTVSLEKYKGKVSLVVNVASDCQLTDRNYLGLKELHKEFGPSHFSVLAF 106
FY F+ + +G+ VSLEKY+G VSLVVNVAS+C TD++Y L++L ++ GP HF+VLAF
Sbjct: 25 FYDFKAVNIRGKLVSLEKYRGSVSLVVNVASECGFTDQHYRALQQLQRDLGPHHFNVLAF 84
Query: 107 PCNQFGESEPRPSKEVESFARKNYGVTFPIFHKIKILGSEGEPAFRFLVDSSKKEPRWNF 166
PCNQFG+ EP +KE+ESFAR+ Y V+FP+F KI + G+ PAF++L +S KEP WNF
Sbjct: 85 PCNQFGQQEPDSNKEIESFARRTYSVSFPMFSKIAVTGTGAHPAFKYLAQTSGKEPTWNF 144
Query: 167 WKYLVNPEGQVVKFWKPEEPIEVIRPDIAALVRQVIIKKKEDL 209
WKYLV P+G+VV W P +E +RP I ALVR++I+ K+EDL
Sbjct: 145 WKYLVAPDGKVVGAWDPTVSVEEVRPQITALVRKLILLKREDL 187
>gi|90903240 glutathione peroxidase 4 isoform C precursor [Homo
sapiens]
Length = 234
Score = 108 bits (271), Expect = 2e-24
Identities = 59/155 (38%), Positives = 87/155 (56%), Gaps = 7/155 (4%)
Query: 46 SFYAFEVKDAKGRTVSLEKYKGKVSLVVNVASDCQLTDRNYLGLKELHKEFGPSHFSVLA 105
S + F KD G V+L+KY+G V +V NVAS T+ NY L +LH + +LA
Sbjct: 77 SMHEFSAKDIDGHMVNLDKYRGFVCIVTNVASQUGKTEVNYTQLVDLHARYAECGLRILA 136
Query: 106 FPCNQFGESEPRPSKEVESFARKNYGVTFPIFHKIKILGSEGEPAFRFLVDSSKKEP--- 162
FPCNQFG+ EP ++E++ FA Y V F +F KI + G + P ++++ K +
Sbjct: 137 FPCNQFGKQEPGSNEEIKEFA-AGYNVKFDMFSKICVNGDDAHPLWKWMKIQPKGKGILG 195
Query: 163 ---RWNFWKYLVNPEGQVVKFWKPEEPIEVIRPDI 194
+WNF K+L++ G VVK + P E VI D+
Sbjct: 196 NAIKWNFTKFLIDKNGCVVKRYGPMEEPLVIEKDL 230
>gi|75709200 glutathione peroxidase 4 isoform A precursor [Homo
sapiens]
Length = 197
Score = 108 bits (271), Expect = 2e-24
Identities = 59/155 (38%), Positives = 87/155 (56%), Gaps = 7/155 (4%)
Query: 46 SFYAFEVKDAKGRTVSLEKYKGKVSLVVNVASDCQLTDRNYLGLKELHKEFGPSHFSVLA 105
S + F KD G V+L+KY+G V +V NVAS T+ NY L +LH + +LA
Sbjct: 40 SMHEFSAKDIDGHMVNLDKYRGFVCIVTNVASQUGKTEVNYTQLVDLHARYAECGLRILA 99
Query: 106 FPCNQFGESEPRPSKEVESFARKNYGVTFPIFHKIKILGSEGEPAFRFLVDSSKKEP--- 162
FPCNQFG+ EP ++E++ FA Y V F +F KI + G + P ++++ K +
Sbjct: 100 FPCNQFGKQEPGSNEEIKEFA-AGYNVKFDMFSKICVNGDDAHPLWKWMKIQPKGKGILG 158
Query: 163 ---RWNFWKYLVNPEGQVVKFWKPEEPIEVIRPDI 194
+WNF K+L++ G VVK + P E VI D+
Sbjct: 159 NAIKWNFTKFLIDKNGCVVKRYGPMEEPLVIEKDL 193
>gi|90903238 glutathione peroxidase 4 isoform B precursor [Homo
sapiens]
Length = 227
Score = 94.4 bits (233), Expect = 6e-20
Identities = 49/130 (37%), Positives = 73/130 (56%), Gaps = 7/130 (5%)
Query: 46 SFYAFEVKDAKGRTVSLEKYKGKVSLVVNVASDCQLTDRNYLGLKELHKEFGPSHFSVLA 105
S + F KD G V+L+KY+G V +V NVAS T+ NY L +LH + +LA
Sbjct: 40 SMHEFSAKDIDGHMVNLDKYRGFVCIVTNVASQUGKTEVNYTQLVDLHARYAECGLRILA 99
Query: 106 FPCNQFGESEPRPSKEVESFARKNYGVTFPIFHKIKILGSEGEPAFRFLVDSSKKEP--- 162
FPCNQFG+ EP ++E++ FA Y V F +F KI + G + P ++++ K +
Sbjct: 100 FPCNQFGKQEPGSNEEIKEFA-AGYNVKFDMFSKICVNGDDAHPLWKWMKIQPKGKGILG 158
Query: 163 ---RWNFWKY 169
+WNF K+
Sbjct: 159 NAIKWNFTKF 168
>gi|41406084 glutathione peroxidase 1 isoform 1 [Homo sapiens]
Length = 203
Score = 85.5 bits (210), Expect = 3e-17
Identities = 60/184 (32%), Positives = 85/184 (46%), Gaps = 29/184 (15%)
Query: 46 SFYAFEVKD-AKGRTVSLEKYKGKVSLVVNVASDCQLTDRNYLGLKELHKEFGPSHFSVL 104
S YAF + A G VSL +GKV L+ NVAS T R+Y + EL + GP VL
Sbjct: 15 SVYAFSARPLAGGEPVSLGSLRGKVLLIENVASLUGTTVRDYTQMNELQRRLGPRGLVVL 74
Query: 105 AFPCNQFGESEPRPSKEVES---FARKNYGV--TFPIFHKIKILGSEGEPAFRFLVDS-- 157
FPCNQFG E ++E+ + + R G F +F K ++ G+ P F FL ++
Sbjct: 75 GFPCNQFGHQENAKNEEILNSLKYVRPGGGFEPNFMLFEKCEVNGAGAHPLFAFLREALP 134
Query: 158 ---------------------SKKEPRWNFWKYLVNPEGQVVKFWKPEEPIEVIRPDIAA 196
+ + WNF K+LV P+G ++ + I PDI A
Sbjct: 135 APSDDATALMTDPKLITWSPVCRNDVAWNFEKFLVGPDGVPLRRYSRRFQTIDIEPDIEA 194
Query: 197 LVRQ 200
L+ Q
Sbjct: 195 LLSQ 198
>gi|4557629 glutathione peroxidase 5 isoform 1 precursor [Homo
sapiens]
Length = 221
Score = 82.0 bits (201), Expect = 3e-16
Identities = 57/169 (33%), Positives = 79/169 (46%), Gaps = 25/169 (14%)
Query: 56 KGRTVSLEKYKGKVSLVVNVASDCQLTDRNYLGLKELHKEFGPSHFSVLAFPCNQFGESE 115
K VS ++Y GK L VNVA+ C LT + Y L L +E P VL FPCNQFG+ E
Sbjct: 50 KNEYVSFKQYVGKHILFVNVATYCGLTAQ-YPELNALQEELKPYGLVVLGFPCNQFGKQE 108
Query: 116 PRPSKEV---ESFARKNYGV--TFPIFHKIKILGSEGEPAFRFLVDS------------- 157
P +KE+ + R G +F +F K + G + + F FL S
Sbjct: 109 PGDNKEILPGLKYVRPGGGFVPSFQLFEKGDVNGEKEQKVFSFLKHSCPHPSEILGTFKS 168
Query: 158 ------SKKEPRWNFWKYLVNPEGQVVKFWKPEEPIEVIRPDIAALVRQ 200
+ RWNF K+LV P+G V W + ++ DI A ++Q
Sbjct: 169 ISWDPVKVHDIRWNFEKFLVGPDGIPVMRWSHRATVSSVKTDILAYLKQ 217
>gi|32967607 glutathione peroxidase 2 [Homo sapiens]
Length = 190
Score = 77.8 bits (190), Expect = 6e-15
Identities = 53/185 (28%), Positives = 77/185 (41%), Gaps = 29/185 (15%)
Query: 46 SFYAFEVKDAKGRTVSLEKYKGKVSLVVNVASDCQLTDRNYLGLKELHKEFGPSHFSVLA 105
SFY G V ++G+ L+ NVAS T R++ L EL F P VL
Sbjct: 7 SFYDLSAISLDGEKVDFNTFRGRAVLIENVASLUGTTTRDFTQLNELQCRF-PRRLVVLG 65
Query: 106 FPCNQFGESEPRPSKEVESFARK-----NYGVTFPIFHKIKILGSEGEPAFRFLVDS--- 157
FPCNQFG E ++E+ + + Y TF + K ++ G P F +L D
Sbjct: 66 FPCNQFGHQENCQNEEILNSLKYVRPGGGYQPTFTLVQKCEVNGQNEHPVFAYLKDKLPY 125
Query: 158 --------------------SKKEPRWNFWKYLVNPEGQVVKFWKPEEPIEVIRPDIAAL 197
+ + WNF K+L+ PEG+ + + P I PDI L
Sbjct: 126 PYDDPFSLMTDPKLIIWSPVRRSDVAWNFEKFLIGPEGEPFRRYSRTFPTINIEPDIKRL 185
Query: 198 VRQVI 202
++ I
Sbjct: 186 LKVAI 190
>gi|6006001 glutathione peroxidase 3 precursor [Homo sapiens]
Length = 226
Score = 73.9 bits (180), Expect = 9e-14
Identities = 51/165 (30%), Positives = 77/165 (46%), Gaps = 25/165 (15%)
Query: 60 VSLEKYKGKVSLVVNVASDCQLTDRNYLGLKELHKEFGPSHFSVLAFPCNQFGESEPRPS 119
+ ++Y GK L VNVAS LT + Y+ L L +E P +L FPCNQFG+ EP +
Sbjct: 54 IPFKQYAGKYVLFVNVASYUGLTGQ-YIELNALQEELAPFGLVILGFPCNQFGKQEPGEN 112
Query: 120 KEV---ESFARKNYGV--TFPIFHKIKILGSEGEPAFRFLVDSSKK-------------E 161
E+ + R G F +F K + G + + + FL +S E
Sbjct: 113 SEILPTLKYVRPGGGFVPNFQLFEKGDVNGEKEQKFYTFLKNSCPPTSELLGTSDRLFWE 172
Query: 162 P------RWNFWKYLVNPEGQVVKFWKPEEPIEVIRPDIAALVRQ 200
P RWNF K+LV P+G + W + ++ DI + +R+
Sbjct: 173 PMKVHDIRWNFEKFLVGPDGIPIMRWHHRTTVSNVKMDILSYMRR 217
>gi|33186887 glutathione peroxidase 6 [Homo sapiens]
Length = 221
Score = 70.5 bits (171), Expect = 1e-12
Identities = 50/165 (30%), Positives = 76/165 (46%), Gaps = 25/165 (15%)
Query: 60 VSLEKYKGKVSLVVNVASDCQLTDRNYLGLKELHKEFGPSHFSVLAFPCNQFGESEPRPS 119
+ +++ GK L VNVA+ L + Y L L +E VLAFPCNQFG+ EP +
Sbjct: 54 IQFKQFAGKHVLFVNVAAYUGLAAQ-YPELNALQEELKNFGVIVLAFPCNQFGKQEPGTN 112
Query: 120 KEVESFAR-----KNYGVTFPIFHKIKILGSEGEPAFRFLVDSSKK-------------E 161
E+ + + +F +F K + G + + F FL +S E
Sbjct: 113 SEILLGLKYVCPGSGFVPSFQLFEKGDVNGEKEQKVFTFLKNSCPPTSDLLGSSSQLFWE 172
Query: 162 P------RWNFWKYLVNPEGQVVKFWKPEEPIEVIRPDIAALVRQ 200
P RWNF K+LV P+G V W + P+ ++ DI ++Q
Sbjct: 173 PMKVHDIRWNFEKFLVGPDGVPVMHWFHQAPVSTVKSDILEYLKQ 217
>gi|41406082 glutathione peroxidase 1 isoform 2 [Homo sapiens]
Length = 98
Score = 59.7 bits (143), Expect = 2e-09
Identities = 34/76 (44%), Positives = 41/76 (53%), Gaps = 1/76 (1%)
Query: 46 SFYAFEVKD-AKGRTVSLEKYKGKVSLVVNVASDCQLTDRNYLGLKELHKEFGPSHFSVL 104
S YAF + A G VSL +GKV L+ NVAS T R+Y + EL + GP VL
Sbjct: 15 SVYAFSARPLAGGEPVSLGSLRGKVLLIENVASLUGTTVRDYTQMNELQRRLGPRGLVVL 74
Query: 105 AFPCNQFGESEPRPSK 120
FPCNQFG R +
Sbjct: 75 GFPCNQFGHQVRRAER 90
>gi|84043967 REV1-like isoform 2 [Homo sapiens]
Length = 1250
Score = 32.3 bits (72), Expect = 0.30
Identities = 19/53 (35%), Positives = 26/53 (49%), Gaps = 1/53 (1%)
Query: 83 DRNYLGLKELHKEFGPSHFSVLAFPCNQFGESEPRPSKEVESF-ARKNYGVTF 134
D Y+ + +L KEFGP +L C + R KE +S A NYG+ F
Sbjct: 669 DLQYMTMAKLQKEFGPKTGQMLYRFCRGLDDRPVRTEKERKSVSAEINYGIRF 721
>gi|7706681 REV1-like isoform 1 [Homo sapiens]
Length = 1251
Score = 32.3 bits (72), Expect = 0.30
Identities = 19/53 (35%), Positives = 26/53 (49%), Gaps = 1/53 (1%)
Query: 83 DRNYLGLKELHKEFGPSHFSVLAFPCNQFGESEPRPSKEVESF-ARKNYGVTF 134
D Y+ + +L KEFGP +L C + R KE +S A NYG+ F
Sbjct: 670 DLQYMTMAKLQKEFGPKTGQMLYRFCRGLDDRPVRTEKERKSVSAEINYGIRF 722
>gi|115511057 hypothetical protein LOC256643 [Homo sapiens]
Length = 682
Score = 32.0 bits (71), Expect = 0.39
Identities = 16/56 (28%), Positives = 28/56 (50%)
Query: 110 QFGESEPRPSKEVESFARKNYGVTFPIFHKIKILGSEGEPAFRFLVDSSKKEPRWN 165
++ E P E S+ +K G P H+++ G G+P R + DS + E +W+
Sbjct: 115 KYSEGIPYKEHERNSYPQKVQGGHSPDDHRVRGSGKGGKPPQRSIADSFRFEGKWH 170
>gi|49533617 sterol O-acyltransferase 1 [Homo sapiens]
Length = 550
Score = 29.3 bits (64), Expect = 2.5
Identities = 14/37 (37%), Positives = 21/37 (56%), Gaps = 2/37 (5%)
Query: 150 AFRFLVDSSKKEPRWN--FWKYLVNPEGQVVKFWKPE 184
AF F+V+ S+K+P WN W L G ++ F+ E
Sbjct: 485 AFNFIVNDSRKKPIWNVLMWTSLFLGNGVLLCFYSQE 521
>gi|125628665 hypothetical protein LOC388284 [Homo sapiens]
Length = 317
Score = 27.7 bits (60), Expect = 7.3
Identities = 16/62 (25%), Positives = 27/62 (43%), Gaps = 1/62 (1%)
Query: 113 ESEPRPSKEVESFARKNYGVTFPIFHKIKILGSEGEPAFRFLVDSSKKEPRWNFWKYLVN 172
+SEP PS + A+K + P+ H + + S R + + P + + Y N
Sbjct: 143 QSEPSPSAKQHKKAKKRKSLGAPVLHAVASMVSAPLETLRLERKAQRLRPLYQYVNY-CN 201
Query: 173 PE 174
PE
Sbjct: 202 PE 203
>gi|170784850 SCY1-like 3 isoform 2 [Homo sapiens]
Length = 742
Score = 27.3 bits (59), Expect = 9.5
Identities = 15/43 (34%), Positives = 19/43 (44%), Gaps = 3/43 (6%)
Query: 157 SSKKEPRWNFWKYLVNPEGQVV--KFWKPEEPIEVIRPDIAAL 197
SSKK W W PE Q V + W P EP + ++ L
Sbjct: 522 SSKKSEEWPDWSEPEEPENQTVNIQIW-PREPCDDVKSQCTTL 563
>gi|170784842 SCY1-like 3 isoform 1 [Homo sapiens]
Length = 688
Score = 27.3 bits (59), Expect = 9.5
Identities = 15/43 (34%), Positives = 19/43 (44%), Gaps = 3/43 (6%)
Query: 157 SSKKEPRWNFWKYLVNPEGQVV--KFWKPEEPIEVIRPDIAAL 197
SSKK W W PE Q V + W P EP + ++ L
Sbjct: 468 SSKKSEEWPDWSEPEEPENQTVNIQIW-PREPCDDVKSQCTTL 509
>gi|24432032 zinc finger protein 503 [Homo sapiens]
Length = 646
Score = 27.3 bits (59), Expect = 9.5
Identities = 12/33 (36%), Positives = 19/33 (57%)
Query: 99 SHFSVLAFPCNQFGESEPRPSKEVESFARKNYG 131
S ++LA C+Q G+ +P PS ++ S A G
Sbjct: 111 SPLALLAQTCSQIGKPDPSPSSKLSSVASNGGG 143
>gi|6715602 glutathione peroxidase 5 isoform 2 precursor [Homo
sapiens]
Length = 100
Score = 27.3 bits (59), Expect = 9.5
Identities = 14/27 (51%), Positives = 17/27 (62%)
Query: 56 KGRTVSLEKYKGKVSLVVNVASDCQLT 82
K VS ++Y GK L VNVA+ C LT
Sbjct: 50 KNEYVSFKQYVGKHILFVNVATYCGLT 76
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.139 0.420
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,146,627
Number of Sequences: 37866
Number of extensions: 356103
Number of successful extensions: 692
Number of sequences better than 10.0: 20
Number of HSP's better than 10.0 without gapping: 14
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 667
Number of HSP's gapped (non-prelim): 20
length of query: 209
length of database: 18,247,518
effective HSP length: 98
effective length of query: 111
effective length of database: 14,536,650
effective search space: 1613568150
effective search space used: 1613568150
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.