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Search of human proteins with 190194416
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|190194416 F-box and leucine-rich repeat protein 15 [Homo
sapiens]
(300 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|190194416 F-box and leucine-rich repeat protein 15 [Homo sapi... 600 e-172
gi|27734755 F-box and leucine-rich repeat protein 20 [Homo sapiens] 89 5e-18
gi|6912466 F-box and leucine-rich repeat protein 7 [Homo sapiens] 83 3e-16
gi|16306582 F-box and leucine-rich repeat protein 2 [Homo sapiens] 79 5e-15
gi|22748931 F-box and leucine-rich repeat protein 14 [Homo sapiens] 78 1e-14
gi|51873034 F-box and leucine-rich repeat protein 9 [Homo sapiens] 74 2e-13
gi|16306591 F-box and leucine-rich repeat protein 9 [Homo sapiens] 74 2e-13
gi|161333852 F-box and leucine-rich repeat protein 13 isoform 1 ... 68 9e-12
gi|16306588 F-box and leucine-rich repeat protein 4 [Homo sapiens] 67 1e-11
gi|254039600 F-box and leucine-rich repeat protein 17 [Homo sapi... 66 3e-11
gi|24025682 F-box and leucine-rich repeat protein 16 [Homo sapiens] 61 1e-09
gi|161333854 F-box and leucine-rich repeat protein 13 isoform 2 ... 60 3e-09
gi|14249170 S-phase kinase-associated protein 2 isoform 2 [Homo ... 54 2e-07
gi|157168349 F-box and leucine-rich repeat protein 19 [Homo sapi... 52 6e-07
gi|16306595 S-phase kinase-associated protein 2 isoform 1 [Homo ... 50 3e-06
gi|164663798 antagonist of mitotic exit network 1 homolog [Homo ... 49 7e-06
gi|54112382 F-box and leucine-rich repeat protein 10 isoform a [... 46 3e-05
gi|54112380 F-box and leucine-rich repeat protein 10 isoform b [... 46 3e-05
gi|16306576 F-box and leucine-rich repeat protein 6 isoform 1 [H... 45 1e-04
gi|61742136 F-box and leucine-rich repeat protein 6 isoform 2 [H... 44 1e-04
gi|22547146 F-box and leucine-rich repeat protein 8 [Homo sapiens] 43 4e-04
gi|21264320 NLR family, pyrin domain containing 6 [Homo sapiens] 40 0.002
gi|24308207 leucine rich repeat containing 47 [Homo sapiens] 38 0.012
gi|8922303 ATP5S-like [Homo sapiens] 37 0.021
gi|194440719 chondroadherin-like [Homo sapiens] 37 0.028
gi|16306580 F-box and leucine-rich repeat protein 11 [Homo sapiens] 36 0.036
gi|16306574 F-box and leucine-rich repeat protein 5 isoform 2 [H... 36 0.036
gi|16306572 F-box and leucine-rich repeat protein 5 isoform 1 [H... 36 0.036
gi|187608777 NF-kappa-B inhibitor-like protein 2 [Homo sapiens] 35 0.062
gi|157426875 F-box and leucine-rich repeat protein 18 [Homo sapi... 35 0.11
>gi|190194416 F-box and leucine-rich repeat protein 15 [Homo
sapiens]
Length = 300
Score = 600 bits (1547), Expect = e-172
Identities = 300/300 (100%), Positives = 300/300 (100%)
Query: 1 MEPPMEPSGGEQEPGAVRFLDLPWEDVLLPHVLNRVPLRQLLRLQRVSRAFRSLVQLHLA 60
MEPPMEPSGGEQEPGAVRFLDLPWEDVLLPHVLNRVPLRQLLRLQRVSRAFRSLVQLHLA
Sbjct: 1 MEPPMEPSGGEQEPGAVRFLDLPWEDVLLPHVLNRVPLRQLLRLQRVSRAFRSLVQLHLA 60
Query: 61 GLRRFDAAQVGPQIPRAALARLLRDAEGLQELALAPCHEWLSDEDLVPVLARNPQLRSVA 120
GLRRFDAAQVGPQIPRAALARLLRDAEGLQELALAPCHEWLSDEDLVPVLARNPQLRSVA
Sbjct: 61 GLRRFDAAQVGPQIPRAALARLLRDAEGLQELALAPCHEWLSDEDLVPVLARNPQLRSVA 120
Query: 121 LGGCGQLSRRALGALAEGCPRLQRLSLAHCDWVDGLALRGLADRCPALEELDLTACRQLK 180
LGGCGQLSRRALGALAEGCPRLQRLSLAHCDWVDGLALRGLADRCPALEELDLTACRQLK
Sbjct: 121 LGGCGQLSRRALGALAEGCPRLQRLSLAHCDWVDGLALRGLADRCPALEELDLTACRQLK 180
Query: 181 DEAIVYLAQRRGAGLRSLSLAVNANVGDAAVQELARNCPELHHLDLTGCLRVGSDGVRTL 240
DEAIVYLAQRRGAGLRSLSLAVNANVGDAAVQELARNCPELHHLDLTGCLRVGSDGVRTL
Sbjct: 181 DEAIVYLAQRRGAGLRSLSLAVNANVGDAAVQELARNCPELHHLDLTGCLRVGSDGVRTL 240
Query: 241 AEYCPVLRSLRVRHCHHVAESSLSRLRKRGVDIDVEPPLHQALVLLQDMAGFAPFVNLQV 300
AEYCPVLRSLRVRHCHHVAESSLSRLRKRGVDIDVEPPLHQALVLLQDMAGFAPFVNLQV
Sbjct: 241 AEYCPVLRSLRVRHCHHVAESSLSRLRKRGVDIDVEPPLHQALVLLQDMAGFAPFVNLQV 300
>gi|27734755 F-box and leucine-rich repeat protein 20 [Homo sapiens]
Length = 436
Score = 89.0 bits (219), Expect = 5e-18
Identities = 65/240 (27%), Positives = 121/240 (50%), Gaps = 4/240 (1%)
Query: 28 LLPHVLNRVPLRQLLRLQRVSRAFRSLVQLHLAGLRRFDAAQVGPQIPRAALARLLRDAE 87
LL + + + + L R +VSRA+ L L + +R D I + + +
Sbjct: 32 LLLRIFSFLDVVTLCRCAQVSRAWNVLA-LDGSNWQRIDLFDFQRDIEGRVVENISKRCG 90
Query: 88 G-LQELALAPCHEWLSDEDLVPVLARNPQLRSVALGGCGQLSRRALGALAEGCPRLQRLS 146
G L++L+L C + D L + + L GC + + +L++ C +L+ L
Sbjct: 91 GFLRKLSLRGCLG-VGDNALRTFAQNCRNIEVLNLNGCTKTTDATCTSLSKFCSKLRHLD 149
Query: 147 LAHCDWVDGLALRGLADRCPALEELDLTACRQLKDEAIVYLAQRRGAGLRSLSLAVNANV 206
LA C + ++L+ L++ CP LE+L+++ C Q+ + I L + G GL++L L +
Sbjct: 150 LASCTSITNMSLKALSEGCPLLEQLNISWCDQVTKDGIQALVRGCG-GLKALFLKGCTQL 208
Query: 207 GDAAVQELARNCPELHHLDLTGCLRVGSDGVRTLAEYCPVLRSLRVRHCHHVAESSLSRL 266
D A++ + +CPEL L+L CL++ +G+ T+ C L+SL C ++ ++ L+ L
Sbjct: 209 EDEALKYIGAHCPELVTLNLQTCLQITDEGLITICRGCHKLQSLCASGCSNITDAILNAL 268
Score = 86.3 bits (212), Expect = 3e-17
Identities = 55/190 (28%), Positives = 93/190 (48%), Gaps = 2/190 (1%)
Query: 77 AALARLLRDAEGLQELALAPCHEWLSDEDLVPVLARNPQLRSVALGGCGQLSRRALGALA 136
A L + L+ L LA C +++ L + P L + + C Q+++ + AL
Sbjct: 133 ATCTSLSKFCSKLRHLDLASCTS-ITNMSLKALSEGCPLLEQLNISWCDQVTKDGIQALV 191
Query: 137 EGCPRLQRLSLAHCDWVDGLALRGLADRCPALEELDLTACRQLKDEAIVYLAQRRGAGLR 196
GC L+ L L C ++ AL+ + CP L L+L C Q+ DE ++ + R L+
Sbjct: 192 RGCGGLKALFLKGCTQLEDEALKYIGAHCPELVTLNLQTCLQITDEGLITIC-RGCHKLQ 250
Query: 197 SLSLAVNANVGDAAVQELARNCPELHHLDLTGCLRVGSDGVRTLAEYCPVLRSLRVRHCH 256
SL + +N+ DA + L +NCP L L++ C ++ G TLA C L + + C
Sbjct: 251 SLCASGCSNITDAILNALGQNCPRLRILEVARCSQLTDVGFTTLARNCHELEKMDLEECV 310
Query: 257 HVAESSLSRL 266
+ +S+L +L
Sbjct: 311 QITDSTLIQL 320
Score = 70.9 bits (172), Expect = 1e-12
Identities = 53/206 (25%), Positives = 93/206 (45%), Gaps = 6/206 (2%)
Query: 73 QIPRAALARLLRDAEGLQELALAPCHEWLSDEDLVPVLARNPQLRSVALGGCGQLSRRAL 132
Q+ AL + L L L C + ++DE L+ + +L+S+ GC ++ L
Sbjct: 207 QLEDEALKYIGAHCPELVTLNLQTCLQ-ITDEGLITICRGCHKLQSLCASGCSNITDAIL 265
Query: 133 GALAEGCPRLQRLSLAHCDWVDGLALRGLADRCPALEELDLTACRQLKDEAIVYLAQRRG 192
AL + CPRL+ L +A C + + LA C LE++DL C Q+ D ++ L+
Sbjct: 266 NALGQNCPRLRILEVARCSQLTDVGFTTLARNCHELEKMDLEECVQITDSTLIQLS-IHC 324
Query: 193 AGLRSLSLAVNANVGDAAVQELARNC---PELHHLDLTGCLRVGSDGVRTLAEYCPVLRS 249
L+ LSL+ + D ++ L +L ++L C + + L + C L
Sbjct: 325 PRLQVLSLSHCELITDDGIRHLGNGACAHDQLEVIELDNCPLITDASLEHL-KSCHSLER 383
Query: 250 LRVRHCHHVAESSLSRLRKRGVDIDV 275
+ + C + + + RLR +I V
Sbjct: 384 IELYDCQQITRAGIKRLRTHLPNIKV 409
Score = 35.8 bits (81), Expect = 0.047
Identities = 18/59 (30%), Positives = 31/59 (52%), Gaps = 1/59 (1%)
Query: 211 VQELARNCPE-LHHLDLTGCLRVGSDGVRTLAEYCPVLRSLRVRHCHHVAESSLSRLRK 268
V+ +++ C L L L GCL VG + +RT A+ C + L + C +++ + L K
Sbjct: 82 VENISKRCGGFLRKLSLRGCLGVGDNALRTFAQNCRNIEVLNLNGCTKTTDATCTSLSK 140
>gi|6912466 F-box and leucine-rich repeat protein 7 [Homo sapiens]
Length = 491
Score = 83.2 bits (204), Expect = 3e-16
Identities = 49/160 (30%), Positives = 82/160 (51%), Gaps = 7/160 (4%)
Query: 116 LRSVALGGCGQLSRRALGALAEGCPRLQRLSLAHCDWVDGLALRGLADRCPALEELDLTA 175
L +V + GC +L+ R L +A+ CP L+RL ++ C + A+ + CP LE LD++
Sbjct: 188 LETVTVSGCRRLTDRGLYTIAQCCPELRRLEVSGCYNISNEAVFDVVSLCPNLEHLDVSG 247
Query: 176 CRQ-----LKDEAIVYLAQRRG--AGLRSLSLAVNANVGDAAVQELARNCPELHHLDLTG 228
C + L EA + L+ G +R L + + D + +A +C +L HL L
Sbjct: 248 CSKVTCISLTREASIKLSPLHGKQISIRYLDMTDCFVLEDEGLHTIAAHCTQLTHLYLRR 307
Query: 229 CLRVGSDGVRTLAEYCPVLRSLRVRHCHHVAESSLSRLRK 268
C+R+ +G+R L YC ++ L V C V++ L + K
Sbjct: 308 CVRLTDEGLRYLVIYCASIKELSVSDCRFVSDFGLREIAK 347
Score = 70.5 bits (171), Expect = 2e-12
Identities = 69/288 (23%), Positives = 116/288 (40%), Gaps = 52/288 (18%)
Query: 26 DVLLPHVLNRVPLRQLLRLQRVSRAFRSLV-------QLHLAGLRRFDAAQVGPQIPRAA 78
D + + + +P QL R RV R + +L + L G + V + +
Sbjct: 119 DHSMVQIFSFLPTNQLCRCARVCRRWYNLAWDPRLWRTIRLTG----ETINVDRAL-KVL 173
Query: 79 LARLLRDAEG----LQELALAPCHEWLSDEDLVPVLARNPQLRSVALGGCGQLSRRALGA 134
RL +D L+ + ++ C L+D L + P+LR + + GC +S A+
Sbjct: 174 TRRLCQDTPNVCLMLETVTVSGCRR-LTDRGLYTIAQCCPELRRLEVSGCYNISNEAVFD 232
Query: 135 LAEGCPRLQRLSLAHCDWVDGLAL----------------------------------RG 160
+ CP L+ L ++ C V ++L
Sbjct: 233 VVSLCPNLEHLDVSGCSKVTCISLTREASIKLSPLHGKQISIRYLDMTDCFVLEDEGLHT 292
Query: 161 LADRCPALEELDLTACRQLKDEAIVYLAQRRGAGLRSLSLAVNANVGDAAVQELARNCPE 220
+A C L L L C +L DE + YL A ++ LS++ V D ++E+A+
Sbjct: 293 IAAHCTQLTHLYLRRCVRLTDEGLRYLVIYC-ASIKELSVSDCRFVSDFGLREIAKLESR 351
Query: 221 LHHLDLTGCLRVGSDGVRTLAEYCPVLRSLRVRHCHHVAESSLSRLRK 268
L +L + C RV G+R +A+YC LR L R C + + + L K
Sbjct: 352 LRYLSIAHCGRVTDVGIRYVAKYCSKLRYLNARGCEGITDHGVEYLAK 399
Score = 68.9 bits (167), Expect = 5e-12
Identities = 49/163 (30%), Positives = 76/163 (46%), Gaps = 1/163 (0%)
Query: 101 LSDEDLVPVLARNPQLRSVALGGCGQLSRRALGALAEGCPRLQRLSLAHCDWVDGLALRG 160
L DE L + A QL + L C +L+ L L C ++ LS++ C +V LR
Sbjct: 285 LEDEGLHTIAAHCTQLTHLYLRRCVRLTDEGLRYLVIYCASIKELSVSDCRFVSDFGLRE 344
Query: 161 LADRCPALEELDLTACRQLKDEAIVYLAQRRGAGLRSLSLAVNANVGDAAVQELARNCPE 220
+A L L + C ++ D I Y+A + + LR L+ + D V+ LA+NC +
Sbjct: 345 IAKLESRLRYLSIAHCGRVTDVGIRYVA-KYCSKLRYLNARGCEGITDHGVEYLAKNCTK 403
Query: 221 LHHLDLTGCLRVGSDGVRTLAEYCPVLRSLRVRHCHHVAESSL 263
L LD+ C V G+ LA C L+ L ++ C + L
Sbjct: 404 LKSLDIGKCPLVSDTGLECLALNCFNLKRLSLKSCESITGQGL 446
Score = 57.8 bits (138), Expect = 1e-08
Identities = 39/156 (25%), Positives = 79/156 (50%), Gaps = 3/156 (1%)
Query: 89 LQELALAPCHEWLSDEDLVPVLARNPQLRSVALGGCGQLSRRALGALAEGCPRLQRLSLA 148
++EL+++ C ++SD L + +LR +++ CG+++ + +A+ C +L+ L+
Sbjct: 326 IKELSVSDCR-FVSDFGLREIAKLESRLRYLSIAHCGRVTDVGIRYVAKYCSKLRYLNAR 384
Query: 149 HCDWVDGLALRGLADRCPALEELDLTACRQLKDEAIVYLAQRRGAGLRSLSLAVNANVGD 208
C+ + + LA C L+ LD+ C + D + LA L+ LSL ++
Sbjct: 385 GCEGITDHGVEYLAKNCTKLKSLDIGKCPLVSDTGLECLA-LNCFNLKRLSLKSCESITG 443
Query: 209 AAVQELARNCPELHHLDLTGCLRVGSDGVRTLAEYC 244
+Q +A NC +L L++ C V + +R + +C
Sbjct: 444 QGLQIVAANCFDLQTLNVQDC-EVSVEALRFVKRHC 478
>gi|16306582 F-box and leucine-rich repeat protein 2 [Homo sapiens]
Length = 423
Score = 79.0 bits (193), Expect = 5e-15
Identities = 50/192 (26%), Positives = 92/192 (47%), Gaps = 2/192 (1%)
Query: 77 AALARLLRDAEGLQELALAPCHEWLSDEDLVPVLARNPQLRSVALGGCGQLSRRALGALA 136
++L ++ ++ L L C + ++D + +L+ + L C ++ +L ++
Sbjct: 94 SSLKTFAQNCRNIEHLNLNGCTK-ITDSTCYSLSRFCSKLKHLDLTSCVSITNSSLKGIS 152
Query: 137 EGCPRLQRLSLAHCDWVDGLALRGLADRCPALEELDLTACRQLKDEAIVYLAQRRGAGLR 196
EGC L+ L+L+ CD + + L C L+ L L C QL+DEA+ ++ Q L
Sbjct: 153 EGCRNLEYLNLSWCDQITKDGIEALVRGCRGLKALLLRGCTQLEDEALKHI-QNYCHELV 211
Query: 197 SLSLAVNANVGDAAVQELARNCPELHHLDLTGCLRVGSDGVRTLAEYCPVLRSLRVRHCH 256
SL+L + + D V ++ R C L L L+GC + + L CP L+ L C
Sbjct: 212 SLNLQSCSRITDEGVVQICRGCHRLQALCLSGCSNLTDASLTALGLNCPRLQILEAARCS 271
Query: 257 HVAESSLSRLRK 268
H+ ++ + L +
Sbjct: 272 HLTDAGFTLLAR 283
Score = 73.9 bits (180), Expect = 2e-13
Identities = 68/243 (27%), Positives = 108/243 (44%), Gaps = 21/243 (8%)
Query: 44 LQRVSRAFRSLVQLHLAGLRRF--DAAQVGPQIPRAALARLLRDAEGLQELALAP----C 97
L+ +S R+L L+L+ + D + + R A LLR L++ AL C
Sbjct: 148 LKGISEGCRNLEYLNLSWCDQITKDGIEALVRGCRGLKALLLRGCTQLEDEALKHIQNYC 207
Query: 98 HEWLS----------DEDLVPVLARNPQLRSVALGGCGQLSRRALGALAEGCPRLQRLSL 147
HE +S DE +V + +L+++ L GC L+ +L AL CPRLQ L
Sbjct: 208 HELVSLNLQSCSRITDEGVVQICRGCHRLQALCLSGCSNLTDASLTALGLNCPRLQILEA 267
Query: 148 AHCDWVDGLALRGLADRCPALEELDLTACRQLKDEAIVYLAQRRGAGLRSLSLAVNANVG 207
A C + LA C LE++DL C + D ++ L+ L++LSL+ +
Sbjct: 268 ARCSHLTDAGFTLLARNCHELEKMDLEECILITDSTLIQLS-IHCPKLQALSLSHCELIT 326
Query: 208 DAAVQELARNC---PELHHLDLTGCLRVGSDGVRTLAEYCPVLRSLRVRHCHHVAESSLS 264
D + L+ + L L+L CL + + L E C L L + C V + +
Sbjct: 327 DDGILHLSNSTCGHERLRVLELDNCLLITDVALEHL-ENCRGLERLELYDCQQVTRAGIK 385
Query: 265 RLR 267
R+R
Sbjct: 386 RMR 388
Score = 66.6 bits (161), Expect = 3e-11
Identities = 53/204 (25%), Positives = 86/204 (42%), Gaps = 13/204 (6%)
Query: 44 LQRVSRAFRSLVQLHLAGLRRFDAAQVGPQIPRAALARLLRDAEGLQELALAPCHEWLSD 103
L+ + LV L+L R I + ++ R LQ L L+ C L+D
Sbjct: 200 LKHIQNYCHELVSLNLQSCSR---------ITDEGVVQICRGCHRLQALCLSGCSN-LTD 249
Query: 104 EDLVPVLARNPQLRSVALGGCGQLSRRALGALAEGCPRLQRLSLAHCDWVDGLALRGLAD 163
L + P+L+ + C L+ LA C L+++ L C + L L+
Sbjct: 250 ASLTALGLNCPRLQILEAARCSHLTDAGFTLLARNCHELEKMDLEECILITDSTLIQLSI 309
Query: 164 RCPALEELDLTACRQLKDEAIVYLAQRRGAG--LRSLSLAVNANVGDAAVQELARNCPEL 221
CP L+ L L+ C + D+ I++L+ LR L L + D A++ L NC L
Sbjct: 310 HCPKLQALSLSHCELITDDGILHLSNSTCGHERLRVLELDNCLLITDVALEHL-ENCRGL 368
Query: 222 HHLDLTGCLRVGSDGVRTLAEYCP 245
L+L C +V G++ + P
Sbjct: 369 ERLELYDCQQVTRAGIKRMRAQLP 392
Score = 62.4 bits (150), Expect = 5e-10
Identities = 36/151 (23%), Positives = 73/151 (48%), Gaps = 1/151 (0%)
Query: 116 LRSVALGGCGQLSRRALGALAEGCPRLQRLSLAHCDWVDGLALRGLADRCPALEELDLTA 175
LR ++L GC + +L A+ C ++ L+L C + L+ C L+ LDLT+
Sbjct: 80 LRKLSLRGCIGVGDSSLKTFAQNCRNIEHLNLNGCTKITDSTCYSLSRFCSKLKHLDLTS 139
Query: 176 CRQLKDEAIVYLAQRRGAGLRSLSLAVNANVGDAAVQELARNCPELHHLDLTGCLRVGSD 235
C + + ++ +++ L L+L+ + ++ L R C L L L GC ++ +
Sbjct: 140 CVSITNSSLKGISE-GCRNLEYLNLSWCDQITKDGIEALVRGCRGLKALLLRGCTQLEDE 198
Query: 236 GVRTLAEYCPVLRSLRVRHCHHVAESSLSRL 266
++ + YC L SL ++ C + + + ++
Sbjct: 199 ALKHIQNYCHELVSLNLQSCSRITDEGVVQI 229
Score = 55.1 bits (131), Expect = 8e-08
Identities = 26/77 (33%), Positives = 44/77 (57%)
Query: 187 LAQRRGAGLRSLSLAVNANVGDAAVQELARNCPELHHLDLTGCLRVGSDGVRTLAEYCPV 246
+++R G LR LSL VGD++++ A+NC + HL+L GC ++ +L+ +C
Sbjct: 72 ISKRCGGFLRKLSLRGCIGVGDSSLKTFAQNCRNIEHLNLNGCTKITDSTCYSLSRFCSK 131
Query: 247 LRSLRVRHCHHVAESSL 263
L+ L + C + SSL
Sbjct: 132 LKHLDLTSCVSITNSSL 148
>gi|22748931 F-box and leucine-rich repeat protein 14 [Homo sapiens]
Length = 418
Score = 77.8 bits (190), Expect = 1e-14
Identities = 56/201 (27%), Positives = 103/201 (51%), Gaps = 11/201 (5%)
Query: 73 QIPRAALARLLRDAEGLQELALAPCHEWLSDEDLVPVLARNPQLRSVALGGCGQLSRRAL 132
QI ++L R+ + +GL+ L L C +++ L+ + +L+S+ L C LS +
Sbjct: 129 QITDSSLGRIAQYLKGLEVLELGGCSN-ITNTGLLLIAWGLQRLKSLNLRSCRHLSDVGI 187
Query: 133 GALA-------EGCPRLQRLSLAHCDWVDGLALRGLADRCPALEELDLTACRQLKDEAIV 185
G LA EGC L++L+L C + L+L+ ++ L L+L+ C + D ++
Sbjct: 188 GHLAGMTRSAAEGCLGLEQLTLQDCQKLTDLSLKHISRGLTGLRLLNLSFCGGISDAGLL 247
Query: 186 YLAQRRGAGLRSLSLAVNANVGDAAVQELARNCPELHHLDLTGCLRVGSDGVRTLAEYCP 245
+L+ LRSL+L N+ D + LA L LD++ C +VG + +A+
Sbjct: 248 HLSHM--GSLRSLNLRSCDNISDTGIMHLAMGSLRLSGLDVSFCDKVGDQSLAYIAQGLD 305
Query: 246 VLRSLRVRHCHHVAESSLSRL 266
L+SL + C H+++ ++R+
Sbjct: 306 GLKSLSLCSC-HISDDGINRM 325
Score = 68.6 bits (166), Expect = 7e-12
Identities = 59/224 (26%), Positives = 103/224 (45%), Gaps = 14/224 (6%)
Query: 47 VSRAFRSLVQLHLAGLRRFDAAQVGPQIPRAALARLLRDAE----GLQELALAPCHEWLS 102
++ + L L+L R +G LA + R A GL++L L C + L+
Sbjct: 164 IAWGLQRLKSLNLRSCRHLSDVGIGH------LAGMTRSAAEGCLGLEQLTLQDCQK-LT 216
Query: 103 DEDLVPVLARNPQLRSVALGGCGQLSRRALGALAEGCPRLQRLSLAHCDWVDGLALRGLA 162
D L + LR + L CG +S L L+ L+ L+L CD + + LA
Sbjct: 217 DLSLKHISRGLTGLRLLNLSFCGGISDAGLLHLSH-MGSLRSLNLRSCDNISDTGIMHLA 275
Query: 163 DRCPALEELDLTACRQLKDEAIVYLAQRRGAGLRSLSLAVNANVGDAAVQELARNCPELH 222
L LD++ C ++ D+++ Y+AQ GL+SLSL + ++ D + + R L
Sbjct: 276 MGSLRLSGLDVSFCDKVGDQSLAYIAQGLD-GLKSLSLC-SCHISDDGINRMVRQMHGLR 333
Query: 223 HLDLTGCLRVGSDGVRTLAEYCPVLRSLRVRHCHHVAESSLSRL 266
L++ C+R+ G+ +AE+ L + + C + + L R+
Sbjct: 334 TLNIGQCVRITDKGLELIAEHLSQLTGIDLYGCTRITKRGLERI 377
Score = 65.1 bits (157), Expect = 7e-11
Identities = 60/229 (26%), Positives = 110/229 (48%), Gaps = 19/229 (8%)
Query: 57 LHLAGLRRFDAAQVGPQIPRAALARLLRDAEGLQELALAPCHEWLSDEDLVPVLARN-PQ 115
L G+RR + R +L+ +++ ++ L L+ C+ L+D L +
Sbjct: 65 LQARGIRRVQILSL-----RRSLSYVIQGMANIESLNLSGCYN-LTDNGLGHAFVQEIGS 118
Query: 116 LRSVALGGCGQLSRRALGALAEGCPRLQRLSLAHCDWVDGLALRGLADRCPALEELDLTA 175
LR++ L C Q++ +LG +A+ L+ L L C + L +A L+ L+L +
Sbjct: 119 LRALNLSLCKQITDSSLGRIAQYLKGLEVLELGGCSNITNTGLLLIAWGLQRLKSLNLRS 178
Query: 176 CRQLKDEAIVYLA-QRRGA-----GLRSLSLAVNANVGDAAVQELARNCPELHHLDLTGC 229
CR L D I +LA R A GL L+L + D +++ ++R L L+L+ C
Sbjct: 179 CRHLSDVGIGHLAGMTRSAAEGCLGLEQLTLQDCQKLTDLSLKHISRGLTGLRLLNLSFC 238
Query: 230 LRVGSDGVRTLAEYCPVLRSLRVRHCHHVAES-----SLSRLRKRGVDI 273
+ G+ L+ + LRSL +R C +++++ ++ LR G+D+
Sbjct: 239 GGISDAGLLHLS-HMGSLRSLNLRSCDNISDTGIMHLAMGSLRLSGLDV 286
Score = 63.5 bits (153), Expect = 2e-10
Identities = 58/205 (28%), Positives = 97/205 (47%), Gaps = 15/205 (7%)
Query: 58 HLAGLRRFDAA----------QVGPQIPRAALARLLRDAEGLQELALAPCHEWLSDEDLV 107
HLAG+ R A Q ++ +L + R GL+ L L+ C +SD L+
Sbjct: 189 HLAGMTRSAAEGCLGLEQLTLQDCQKLTDLSLKHISRGLTGLRLLNLSFCGG-ISDAGLL 247
Query: 108 PVLARNPQLRSVALGGCGQLSRRALGALAEGCPRLQRLSLAHCDWVDGLALRGLADRCPA 167
L+ LRS+ L C +S + LA G RL L ++ CD V +L +A
Sbjct: 248 H-LSHMGSLRSLNLRSCDNISDTGIMHLAMGSLRLSGLDVSFCDKVGDQSLAYIAQGLDG 306
Query: 168 LEELDLTACRQLKDEAIVYLAQRRGAGLRSLSLAVNANVGDAAVQELARNCPELHHLDLT 227
L+ L L +C + D+ I + R+ GLR+L++ + D ++ +A + +L +DL
Sbjct: 307 LKSLSLCSCH-ISDDGINRMV-RQMHGLRTLNIGQCVRITDKGLELIAEHLSQLTGIDLY 364
Query: 228 GCLRVGSDGVRTLAEYCPVLRSLRV 252
GC R+ G+ + + P L+ L +
Sbjct: 365 GCTRITKRGLERITQ-LPCLKVLNL 388
>gi|51873034 F-box and leucine-rich repeat protein 9 [Homo sapiens]
Length = 223
Score = 73.6 bits (179), Expect = 2e-13
Identities = 57/183 (31%), Positives = 84/183 (45%), Gaps = 23/183 (12%)
Query: 123 GCGQLSRRALGALAEGCPRLQRLSLAHCDWVDGLA-----LRGLADRCP----------- 166
G G+ +ALG + +L LSLAHC + G D CP
Sbjct: 16 GRGRELAQALGCMHGAPSQLASLSLAHCSSLKSRPELEHQASGTKDACPEPQGPSLLTLR 75
Query: 167 ALEELDLTACRQLKDEAIVYLAQRRGAGLRSLSLAVNANVGDAAVQELARNCPELHHLDL 226
AL+ELDLTAC +L D ++ + Q LR LSL++ + D + +AR CP L HL L
Sbjct: 76 ALQELDLTACSKLTDASLAKVLQF--LQLRQLSLSLLPELTDNGLVAVARGCPSLEHLAL 133
Query: 227 TGCLRVGSDGVRTLAEYCPVLRSLRVRHCHHVAESSLSRL-----RKRGVDIDVEPPLHQ 281
+ C R+ G A P L+ L + C + E +L + + R +D+ P ++
Sbjct: 134 SHCSRLSDKGWAQAASSWPRLQHLNLSSCSQLIEQTLDAIGQACRQLRVLDVATCPGINM 193
Query: 282 ALV 284
A V
Sbjct: 194 AAV 196
Score = 62.4 bits (150), Expect = 5e-10
Identities = 44/133 (33%), Positives = 69/133 (51%), Gaps = 3/133 (2%)
Query: 89 LQELALAPCHEWLSDEDLVPVLARNPQLRSVALGGCGQLSRRALGALAEGCPRLQRLSLA 148
LQEL L C + L+D L VL + QLR ++L +L+ L A+A GCP L+ L+L+
Sbjct: 77 LQELDLTACSK-LTDASLAKVL-QFLQLRQLSLSLLPELTDNGLVAVARGCPSLEHLALS 134
Query: 149 HCDWVDGLALRGLADRCPALEELDLTACRQLKDEAIVYLAQRRGAGLRSLSLAVNANVGD 208
HC + A P L+ L+L++C QL ++ + + Q LR L +A +
Sbjct: 135 HCSRLSDKGWAQAASSWPRLQHLNLSSCSQLIEQTLDAIGQ-ACRQLRVLDVATCPGINM 193
Query: 209 AAVQELARNCPEL 221
AAV+ P++
Sbjct: 194 AAVRRFQAQLPQV 206
>gi|16306591 F-box and leucine-rich repeat protein 9 [Homo sapiens]
Length = 223
Score = 73.6 bits (179), Expect = 2e-13
Identities = 57/183 (31%), Positives = 84/183 (45%), Gaps = 23/183 (12%)
Query: 123 GCGQLSRRALGALAEGCPRLQRLSLAHCDWVDGLA-----LRGLADRCP----------- 166
G G+ +ALG + +L LSLAHC + G D CP
Sbjct: 16 GRGRELAQALGCMHGAPSQLASLSLAHCSSLKSRPELEHQASGTKDACPEPQGPSLLTLR 75
Query: 167 ALEELDLTACRQLKDEAIVYLAQRRGAGLRSLSLAVNANVGDAAVQELARNCPELHHLDL 226
AL+ELDLTAC +L D ++ + Q LR LSL++ + D + +AR CP L HL L
Sbjct: 76 ALQELDLTACSKLTDASLAKVLQF--LQLRQLSLSLLPELTDNGLVAVARGCPSLEHLAL 133
Query: 227 TGCLRVGSDGVRTLAEYCPVLRSLRVRHCHHVAESSLSRL-----RKRGVDIDVEPPLHQ 281
+ C R+ G A P L+ L + C + E +L + + R +D+ P ++
Sbjct: 134 SHCSRLSDKGWAQAASSWPRLQHLNLSSCSQLIEQTLDAIGQACRQLRVLDVATCPGINM 193
Query: 282 ALV 284
A V
Sbjct: 194 AAV 196
Score = 62.4 bits (150), Expect = 5e-10
Identities = 44/133 (33%), Positives = 69/133 (51%), Gaps = 3/133 (2%)
Query: 89 LQELALAPCHEWLSDEDLVPVLARNPQLRSVALGGCGQLSRRALGALAEGCPRLQRLSLA 148
LQEL L C + L+D L VL + QLR ++L +L+ L A+A GCP L+ L+L+
Sbjct: 77 LQELDLTACSK-LTDASLAKVL-QFLQLRQLSLSLLPELTDNGLVAVARGCPSLEHLALS 134
Query: 149 HCDWVDGLALRGLADRCPALEELDLTACRQLKDEAIVYLAQRRGAGLRSLSLAVNANVGD 208
HC + A P L+ L+L++C QL ++ + + Q LR L +A +
Sbjct: 135 HCSRLSDKGWAQAASSWPRLQHLNLSSCSQLIEQTLDAIGQ-ACRQLRVLDVATCPGINM 193
Query: 209 AAVQELARNCPEL 221
AAV+ P++
Sbjct: 194 AAVRRFQAQLPQV 206
>gi|161333852 F-box and leucine-rich repeat protein 13 isoform 1
[Homo sapiens]
Length = 735
Score = 68.2 bits (165), Expect = 9e-12
Identities = 53/204 (25%), Positives = 96/204 (47%), Gaps = 25/204 (12%)
Query: 89 LQELALAPCHEWLSDEDLVPVLARNPQLRSVALGGCGQLSRRALGALA------------ 136
++EL L+ C LSD ++ + R P L ++L C L+ + +G +
Sbjct: 481 IRELNLSNCVR-LSDASVMKLSERCPNLNYLSLRNCEHLTAQGIGYIVNIFSLVSIDLSG 539
Query: 137 -----EGC------PRLQRLSLAHCDWVDGLALRGLADRCPALEELDLTACRQLKDEAIV 185
EG +L+ LS++ C + ++ LE LD++ C QL D I
Sbjct: 540 TDISNEGLNVLSRHKKLKELSVSECYRITDDGIQAFCKSSLILEHLDVSYCSQLSDMIIK 599
Query: 186 YLAQRRGAGLRSLSLAVNANVGDAAVQELARNCPELHHLDLTGCLRVGSDGVRTLAEYCP 245
LA L SLS+A + D+A++ L+ C LH LD++GC+ + + L C
Sbjct: 600 ALAIYC-INLTSLSIAGCPKITDSAMEMLSAKCHYLHILDISGCVLLTDQILEDLQIGCK 658
Query: 246 VLRSLRVRHCHHVAESSLSRLRKR 269
LR L++++C ++++ + R+ +
Sbjct: 659 QLRILKMQYCTNISKKAAQRMSSK 682
Score = 58.5 bits (140), Expect = 7e-09
Identities = 48/202 (23%), Positives = 88/202 (43%), Gaps = 26/202 (12%)
Query: 89 LQELALAPCHEWLSDEDLVPVLARNPQLRSVALGGCGQLSRRALGALAEG--CPRLQRLS 146
L + +A C + ++D L L+ QL + L C ++ L +G R++ L+
Sbjct: 428 LSHIYMADC-KGITDSSLRS-LSPLKQLTVLNLANCVRIGDMGLKQFLDGPASMRIRELN 485
Query: 147 LAHCDWVDGLALRGLADRCPALEELDLTACRQLKDEAIVYLAQ----------------- 189
L++C + ++ L++RCP L L L C L + I Y+
Sbjct: 486 LSNCVRLSDASVMKLSERCPNLNYLSLRNCEHLTAQGIGYIVNIFSLVSIDLSGTDISNE 545
Query: 190 -----RRGAGLRSLSLAVNANVGDAAVQELARNCPELHHLDLTGCLRVGSDGVRTLAEYC 244
R L+ LS++ + D +Q ++ L HLD++ C ++ ++ LA YC
Sbjct: 546 GLNVLSRHKKLKELSVSECYRITDDGIQAFCKSSLILEHLDVSYCSQLSDMIIKALAIYC 605
Query: 245 PVLRSLRVRHCHHVAESSLSRL 266
L SL + C + +S++ L
Sbjct: 606 INLTSLSIAGCPKITDSAMEML 627
Score = 51.6 bits (122), Expect = 8e-07
Identities = 44/194 (22%), Positives = 82/194 (42%), Gaps = 7/194 (3%)
Query: 74 IPRAALARLLRDAEGLQELALAPCHEWLSDEDLVPVLARNP--QLRSVALGGCGQLSRRA 131
I + L R LQ L+LA C + +D+ L + N +L + L GC Q+S +
Sbjct: 283 ITNRTMRLLPRHFHNLQNLSLAYCRRF-TDKGLQYLNLGNGCHKLIYLDLSGCTQISVQG 341
Query: 132 LGALAEGCPRLQRLSLAHCDWVDGLALRGLADRCPALEELDLTACRQLKDEAIVYLAQRR 191
+A C + L++ + ++ L ++C + L T + D L+
Sbjct: 342 FRYIANSCTGIMHLTINDMPTLTDNCVKALVEKCSRITSLVFTGAPHISDCTFRALS--- 398
Query: 192 GAGLRSLSLAVNANVGDAAVQELARNCPELHHLDLTGCLRVGSDGVRTLAEYCPVLRSLR 251
LR + N V DA+ + + +N P L H+ + C + +R+L+ L L
Sbjct: 399 ACKLRKIRFEGNKRVTDASFKFIDKNYPNLSHIYMADCKGITDSSLRSLSP-LKQLTVLN 457
Query: 252 VRHCHHVAESSLSR 265
+ +C + + L +
Sbjct: 458 LANCVRIGDMGLKQ 471
Score = 48.5 bits (114), Expect = 7e-06
Identities = 42/168 (25%), Positives = 74/168 (44%), Gaps = 5/168 (2%)
Query: 101 LSDEDLVPVLARNPQLRSVALGGCGQLSRRALGALAEGCPRLQRLSLAHCDWVDGLALRG 160
+ D+ +V L R +L + L G L R C LQ L+++ C ++R
Sbjct: 207 IPDKYIVSTLQRW-RLNVLRLNFRGCLLRPKTFRSVSHCRNLQELNVSDCPTFTDESMRH 265
Query: 161 LADRCPALEELDLTACRQLKDEAIVYLAQRRGAGLRSLSLAVNANVGDAAVQ--ELARNC 218
+++ CP + L+L+ + L R L++LSLA D +Q L C
Sbjct: 266 ISEGCPGVLCLNLS--NTTITNRTMRLLPRHFHNLQNLSLAYCRRFTDKGLQYLNLGNGC 323
Query: 219 PELHHLDLTGCLRVGSDGVRTLAEYCPVLRSLRVRHCHHVAESSLSRL 266
+L +LDL+GC ++ G R +A C + L + + ++ + L
Sbjct: 324 HKLIYLDLSGCTQISVQGFRYIANSCTGIMHLTINDMPTLTDNCVKAL 371
Score = 45.8 bits (107), Expect = 5e-05
Identities = 34/152 (22%), Positives = 67/152 (44%), Gaps = 2/152 (1%)
Query: 116 LRSVALGGCGQLSRRALGALAEGCPRLQRLSLAHCDWVDGLALRGLADRCPALEELDLTA 175
L+ + + C + ++ ++EGCP + L+L++ + +R L L+ L L
Sbjct: 247 LQELNVSDCPTFTDESMRHISEGCPGVLCLNLSNTT-ITNRTMRLLPRHFHNLQNLSLAY 305
Query: 176 CRQLKDEAIVYLAQRRGAG-LRSLSLAVNANVGDAAVQELARNCPELHHLDLTGCLRVGS 234
CR+ D+ + YL G L L L+ + + +A +C + HL + +
Sbjct: 306 CRRFTDKGLQYLNLGNGCHKLIYLDLSGCTQISVQGFRYIANSCTGIMHLTINDMPTLTD 365
Query: 235 DGVRTLAEYCPVLRSLRVRHCHHVAESSLSRL 266
+ V+ L E C + SL H+++ + L
Sbjct: 366 NCVKALVEKCSRITSLVFTGAPHISDCTFRAL 397
>gi|16306588 F-box and leucine-rich repeat protein 4 [Homo sapiens]
Length = 621
Score = 67.4 bits (163), Expect = 1e-11
Identities = 50/164 (30%), Positives = 73/164 (44%), Gaps = 3/164 (1%)
Query: 106 LVPVLARNPQLRSVALGGCGQLSRRALGALAEG--CPRLQRLSLAHCDWVDGLALRGLAD 163
L+ +L +L+ ++LG C + + A G C +L+ L L C + + LA
Sbjct: 443 LLSILNFCSELQHLSLGSCVMIEDYDVIASMIGAKCKKLRTLDLWRCKNITENGIAELAS 502
Query: 164 RCPALEELDLTACRQLKDEAIVYLA-QRRGAGLRSLSLAVNANVGDAAVQELARNCPELH 222
CP LEELDL C L+ + + L+ L L N +V D + ELA NC L
Sbjct: 503 GCPLLEELDLGWCPTLQSSTGCFTRLAHQLPNLQKLFLTANRSVCDTDIDELACNCTRLQ 562
Query: 223 HLDLTGCLRVGSDGVRTLAEYCPVLRSLRVRHCHHVAESSLSRL 266
LD+ G V +R L E C L L V C + ++ L
Sbjct: 563 QLDILGTRMVSPASLRKLLESCKDLSLLDVSFCSQIDNRAVLEL 606
Score = 51.6 bits (122), Expect = 8e-07
Identities = 44/167 (26%), Positives = 70/167 (41%), Gaps = 27/167 (16%)
Query: 127 LSRRALGALAEGCPRLQRLSLAHCD------------------------WVDGLALRGLA 162
L+ L ++E CP LQ L+L+ CD V+ AL +
Sbjct: 388 LNETCLEVISEMCPNLQALNLSSCDKLPPQAFNHIAKLCSLKRLVLYRTKVEQTALLSIL 447
Query: 163 DRCPALEELDLTACRQLKD-EAIVYLAQRRGAGLRSLSLAVNANVGDAAVQELARNCPEL 221
+ C L+ L L +C ++D + I + + LR+L L N+ + + ELA CP L
Sbjct: 448 NFCSELQHLSLGSCVMIEDYDVIASMIGAKCKKLRTLDLWRCKNITENGIAELASGCPLL 507
Query: 222 HHLDLTGC--LRVGSDGVRTLAEYCPVLRSLRVRHCHHVAESSLSRL 266
LDL C L+ + LA P L+ L + V ++ + L
Sbjct: 508 EELDLGWCPTLQSSTGCFTRLAHQLPNLQKLFLTANRSVCDTDIDEL 554
Score = 50.8 bits (120), Expect = 1e-06
Identities = 34/127 (26%), Positives = 63/127 (49%), Gaps = 5/127 (3%)
Query: 142 LQRLSLAHCDWVDGLALRGLADRCPALEELDLTACRQLKDEAIVYLAQRRGAGLRSLSLA 201
L RL L+ +++ L +++ CP L+ L+L++C +L +A ++A+ L+ L L
Sbjct: 377 LVRLELSCSHFLNETCLEVISEMCPNLQALNLSSCDKLPPQAFNHIAKL--CSLKRLVL- 433
Query: 202 VNANVGDAAVQELARNCPELHHLDLTGCLRVGSDGV--RTLAEYCPVLRSLRVRHCHHVA 259
V A+ + C EL HL L C+ + V + C LR+L + C ++
Sbjct: 434 YRTKVEQTALLSILNFCSELQHLSLGSCVMIEDYDVIASMIGAKCKKLRTLDLWRCKNIT 493
Query: 260 ESSLSRL 266
E+ ++ L
Sbjct: 494 ENGIAEL 500
Score = 29.3 bits (64), Expect = 4.4
Identities = 21/86 (24%), Positives = 36/86 (41%), Gaps = 1/86 (1%)
Query: 73 QIPRAALARLLRDAEGLQELALAPCHEWLSDEDLVPVLARNPQLRSVALGGCGQLSRRAL 132
Q RL LQ+L L + + D D+ + +L+ + + G +S +L
Sbjct: 519 QSSTGCFTRLAHQLPNLQKLFLT-ANRSVCDTDIDELACNCTRLQQLDILGTRMVSPASL 577
Query: 133 GALAEGCPRLQRLSLAHCDWVDGLAL 158
L E C L L ++ C +D A+
Sbjct: 578 RKLLESCKDLSLLDVSFCSQIDNRAV 603
>gi|254039600 F-box and leucine-rich repeat protein 17 [Homo
sapiens]
Length = 303
Score = 66.2 bits (160), Expect = 3e-11
Identities = 47/169 (27%), Positives = 84/169 (49%), Gaps = 3/169 (1%)
Query: 101 LSDEDLVPVLARNPQLRSVALGGCGQLSRRALGALAEGCPRLQRLSLAHCDWVDGLALRG 160
+SD + + + P L C QLS ++ A+A CP LQ++ + + D + L+
Sbjct: 1 MSDNGVCVLAFKCPGLLRYTAYRCKQLSDTSIIAVASHCPLLQKVHVGNQDKLTDEGLKQ 60
Query: 161 LADRCPALEELDLTACRQLKDEAIVYLAQRRGAGLRSLSLAVNANVGDAAVQELARNCPE 220
L +C L+++ C ++ DE ++ +A + L+ + + N V D +V+ A +CPE
Sbjct: 61 LGSKCRELKDIHFGQCYKISDEGMIVIA-KGCLKLQRIYMQENKLVTDQSVKAFAEHCPE 119
Query: 221 LHHLDLTGCLRVGSDGVRTLAEYCPVLRSLRVRHCHHVAESSLSRLRKR 269
L ++ GC V S GV L + L SL +RH + ++ + KR
Sbjct: 120 LQYVGFMGC-SVTSKGVIHLTK-LRNLSSLDLRHITELDNETVMEIVKR 166
Score = 46.6 bits (109), Expect = 3e-05
Identities = 43/202 (21%), Positives = 84/202 (41%), Gaps = 27/202 (13%)
Query: 89 LQELALAPCHEWLSDEDLVPVLARNPQLRSVALGGCGQLSRRALGALAEGCPRLQ----- 143
L+++ C++ +SDE ++ + +L+ + + ++ +++ A AE CP LQ
Sbjct: 68 LKDIHFGQCYK-ISDEGMIVIAKGCLKLQRIYMQENKLVTDQSVKAFAEHCPELQYVGFM 126
Query: 144 -------------------RLSLAHCDWVDGLALRGLADRCPALEELDLTACRQLKDEAI 184
L L H +D + + RC L L+L + D +
Sbjct: 127 GCSVTSKGVIHLTKLRNLSSLDLRHITELDNETVMEIVKRCKNLSSLNLCLNWIINDRCV 186
Query: 185 VYLAQRRGAGLRSLSLAVNANVGDAAVQELARNCPELHHLDLTGCLRVGSDGVRTLAEYC 244
+A + G L+ L L V+ + D A+ + R + +D+ C + G +A+
Sbjct: 187 EVIA-KEGQNLKELYL-VSCKITDYALIAIGRYSMTIETVDVGWCKEITDQGATLIAQSS 244
Query: 245 PVLRSLRVRHCHHVAESSLSRL 266
LR L + C V E ++ +L
Sbjct: 245 KSLRYLGLMRCDKVNEVTVEQL 266
Score = 35.0 bits (79), Expect = 0.081
Identities = 19/85 (22%), Positives = 43/85 (50%), Gaps = 2/85 (2%)
Query: 82 LLRDAEGLQELALAPCHEWLSDEDLVPVLARNPQLRSVALGGCGQLSRRALGALAEGCPR 141
+ ++ + L+EL L C ++D L+ + + + +V +G C +++ + +A+
Sbjct: 189 IAKEGQNLKELYLVSCK--ITDYALIAIGRYSMTIETVDVGWCKEITDQGATLIAQSSKS 246
Query: 142 LQRLSLAHCDWVDGLALRGLADRCP 166
L+ L L CD V+ + + L + P
Sbjct: 247 LRYLGLMRCDKVNEVTVEQLVQQYP 271
>gi|24025682 F-box and leucine-rich repeat protein 16 [Homo sapiens]
Length = 479
Score = 60.8 bits (146), Expect = 1e-09
Identities = 45/163 (27%), Positives = 74/163 (45%), Gaps = 3/163 (1%)
Query: 101 LSDEDLVPVLARNPQLRSVALGGCGQLSRRALGALAEGCPRLQRLSLAHCDWVDGLALRG 160
++D L +L + + + L GC + L + R+ LS++ C V A+
Sbjct: 205 ITDAGLEVMLEQMQGVVRLELSGCNDFTEAGLWSSLSA--RITSLSVSDCINVADDAIAA 262
Query: 161 LADRCPALEELDLTACRQLKDEAIVYLAQRRGAGLRSLSLAVNANVGDAAVQELARNCPE 220
++ P L EL L A + D A+ Y R+G +L L + + V + + P
Sbjct: 263 ISQLLPNLAELSLQAYH-VTDTALAYFTARQGHSTHTLRLLSCWEITNHGVVNVVHSLPN 321
Query: 221 LHHLDLTGCLRVGSDGVRTLAEYCPVLRSLRVRHCHHVAESSL 263
L L L+GC +V DGV +AE LRSL + C + + +L
Sbjct: 322 LTALSLSGCSKVTDDGVELVAENLRKLRSLDLSWCPRITDMAL 364
Score = 54.3 bits (129), Expect = 1e-07
Identities = 47/172 (27%), Positives = 79/172 (45%), Gaps = 5/172 (2%)
Query: 84 RDAEGLQELALAPCHEWLSDEDLVPVLARNPQLRSVALGGCGQLSRRALGALAEGCPRLQ 143
R L L C E +++ +V V+ P L +++L GC +++ + +AE +L+
Sbjct: 291 RQGHSTHTLRLLSCWE-ITNHGVVNVVHSLPNLTALSLSGCSKVTDDGVELVAENLRKLR 349
Query: 144 RLSLAHCDWVDGLALRGLADRCPALEELDLTACRQLKDEAIVYLAQRRGAGLRSLSLAVN 203
L L+ C + +AL +A LEEL L C ++ D + YL+ + LRSL L
Sbjct: 350 SLDLSWCPRITDMALEYVACDLHRLEELVLDRCVRITDTGLSYLSTM--SSLRSLYLRWC 407
Query: 204 ANVGDAAVQELARNCPELHHLDLTGCLRVGSDGVRTLAEYCPVLRSLRVRHC 255
V D ++ L L L GC + + G+ L + L L + +C
Sbjct: 408 CQVQDFGLKHLLA-LGSLRLLSPAGCPLLTTTGLSGLVQ-LQELEELELTNC 457
Score = 50.4 bits (119), Expect = 2e-06
Identities = 47/193 (24%), Positives = 87/193 (45%), Gaps = 4/193 (2%)
Query: 74 IPRAALARLLRDAEGLQELALAPCHEWLSDEDLVPVLARNPQLRSVALGGCGQLSRRALG 133
I A L +L +G+ L L+ C+++ + AR + S+++ C ++ A+
Sbjct: 205 ITDAGLEVMLEQMQGVVRLELSGCNDFTEAGLWSSLSAR---ITSLSVSDCINVADDAIA 261
Query: 134 ALAEGCPRLQRLSLAHCDWVDGLALRGLADRCPALEELDLTACRQLKDEAIVYLAQRRGA 193
A+++ P L LSL D A + + L L +C ++ + +V +
Sbjct: 262 AISQLLPNLAELSLQAYHVTDTALAYFTARQGHSTHTLRLLSCWEITNHGVVNVVHSL-P 320
Query: 194 GLRSLSLAVNANVGDAAVQELARNCPELHHLDLTGCLRVGSDGVRTLAEYCPVLRSLRVR 253
L +LSL+ + V D V+ +A N +L LDL+ C R+ + +A L L +
Sbjct: 321 NLTALSLSGCSKVTDDGVELVAENLRKLRSLDLSWCPRITDMALEYVACDLHRLEELVLD 380
Query: 254 HCHHVAESSLSRL 266
C + ++ LS L
Sbjct: 381 RCVRITDTGLSYL 393
Score = 41.2 bits (95), Expect = 0.001
Identities = 51/162 (31%), Positives = 72/162 (44%), Gaps = 8/162 (4%)
Query: 31 HVLNRVPLRQLLRLQRVSRAFRSLVQLHLAGLRRFDAAQVG--PQIPRAALARLLRDAEG 88
+V++ +P L L S+ V+L LR+ + + P+I AL + D
Sbjct: 314 NVVHSLPNLTALSLSGCSKVTDDGVELVAENLRKLRSLDLSWCPRITDMALEYVACDLHR 373
Query: 89 LQELALAPCHEWLSDEDLVPVLARNPQLRSVALGGCGQLSRRALG-ALAEGCPRLQRLSL 147
L+EL L C ++D L L+ LRS+ L C Q+ L LA G RL LS
Sbjct: 374 LEELVLDRCVR-ITDTGL-SYLSTMSSLRSLYLRWCCQVQDFGLKHLLALGSLRL--LSP 429
Query: 148 AHCDWVDGLALRGLADRCPALEELDLTACRQLKDEAIVYLAQ 189
A C + L GL + LEEL+LT C E Y +Q
Sbjct: 430 AGCPLLTTTGLSGLV-QLQELEELELTNCPGATPELFKYFSQ 470
>gi|161333854 F-box and leucine-rich repeat protein 13 isoform 2
[Homo sapiens]
Length = 690
Score = 59.7 bits (143), Expect = 3e-09
Identities = 40/162 (24%), Positives = 84/162 (51%), Gaps = 11/162 (6%)
Query: 115 QLRSVALGGCGQLSRRALGALAEGCPRLQRLSLAHCDWVDGLALRGLADRCPALEELDLT 174
++R + L C +LS ++ L+E CP L LSL +C+ + + G +L +DL+
Sbjct: 480 RIRELNLSNCVRLSDASVMKLSERCPNLNYLSLRNCEHLTAQGI-GYIVNIFSLVSIDLS 538
Query: 175 ACRQLKDEAIVYLAQRRGAGLRSLSLAV-------NANVGDAAVQELARNCPELHHLDLT 227
+ +E + L++ + L+ LS++ + D+A++ L+ C LH LD++
Sbjct: 539 GT-DISNEGLNVLSRHKK--LKELSVSECYRITDDGIQITDSAMEMLSAKCHYLHILDIS 595
Query: 228 GCLRVGSDGVRTLAEYCPVLRSLRVRHCHHVAESSLSRLRKR 269
GC+ + + L C LR L++++C ++++ + R+ +
Sbjct: 596 GCVLLTDQILEDLQIGCKQLRILKMQYCTNISKKAAQRMSSK 637
Score = 51.6 bits (122), Expect = 8e-07
Identities = 44/194 (22%), Positives = 82/194 (42%), Gaps = 7/194 (3%)
Query: 74 IPRAALARLLRDAEGLQELALAPCHEWLSDEDLVPVLARNP--QLRSVALGGCGQLSRRA 131
I + L R LQ L+LA C + +D+ L + N +L + L GC Q+S +
Sbjct: 283 ITNRTMRLLPRHFHNLQNLSLAYCRRF-TDKGLQYLNLGNGCHKLIYLDLSGCTQISVQG 341
Query: 132 LGALAEGCPRLQRLSLAHCDWVDGLALRGLADRCPALEELDLTACRQLKDEAIVYLAQRR 191
+A C + L++ + ++ L ++C + L T + D L+
Sbjct: 342 FRYIANSCTGIMHLTINDMPTLTDNCVKALVEKCSRITSLVFTGAPHISDCTFRALS--- 398
Query: 192 GAGLRSLSLAVNANVGDAAVQELARNCPELHHLDLTGCLRVGSDGVRTLAEYCPVLRSLR 251
LR + N V DA+ + + +N P L H+ + C + +R+L+ L L
Sbjct: 399 ACKLRKIRFEGNKRVTDASFKFIDKNYPNLSHIYMADCKGITDSSLRSLSP-LKQLTVLN 457
Query: 252 VRHCHHVAESSLSR 265
+ +C + + L +
Sbjct: 458 LANCVRIGDMGLKQ 471
Score = 48.5 bits (114), Expect = 7e-06
Identities = 42/168 (25%), Positives = 74/168 (44%), Gaps = 5/168 (2%)
Query: 101 LSDEDLVPVLARNPQLRSVALGGCGQLSRRALGALAEGCPRLQRLSLAHCDWVDGLALRG 160
+ D+ +V L R +L + L G L R C LQ L+++ C ++R
Sbjct: 207 IPDKYIVSTLQRW-RLNVLRLNFRGCLLRPKTFRSVSHCRNLQELNVSDCPTFTDESMRH 265
Query: 161 LADRCPALEELDLTACRQLKDEAIVYLAQRRGAGLRSLSLAVNANVGDAAVQ--ELARNC 218
+++ CP + L+L+ + L R L++LSLA D +Q L C
Sbjct: 266 ISEGCPGVLCLNLS--NTTITNRTMRLLPRHFHNLQNLSLAYCRRFTDKGLQYLNLGNGC 323
Query: 219 PELHHLDLTGCLRVGSDGVRTLAEYCPVLRSLRVRHCHHVAESSLSRL 266
+L +LDL+GC ++ G R +A C + L + + ++ + L
Sbjct: 324 HKLIYLDLSGCTQISVQGFRYIANSCTGIMHLTINDMPTLTDNCVKAL 371
Score = 45.8 bits (107), Expect = 5e-05
Identities = 34/152 (22%), Positives = 67/152 (44%), Gaps = 2/152 (1%)
Query: 116 LRSVALGGCGQLSRRALGALAEGCPRLQRLSLAHCDWVDGLALRGLADRCPALEELDLTA 175
L+ + + C + ++ ++EGCP + L+L++ + +R L L+ L L
Sbjct: 247 LQELNVSDCPTFTDESMRHISEGCPGVLCLNLSNTT-ITNRTMRLLPRHFHNLQNLSLAY 305
Query: 176 CRQLKDEAIVYLAQRRGAG-LRSLSLAVNANVGDAAVQELARNCPELHHLDLTGCLRVGS 234
CR+ D+ + YL G L L L+ + + +A +C + HL + +
Sbjct: 306 CRRFTDKGLQYLNLGNGCHKLIYLDLSGCTQISVQGFRYIANSCTGIMHLTINDMPTLTD 365
Query: 235 DGVRTLAEYCPVLRSLRVRHCHHVAESSLSRL 266
+ V+ L E C + SL H+++ + L
Sbjct: 366 NCVKALVEKCSRITSLVFTGAPHISDCTFRAL 397
Score = 28.5 bits (62), Expect = 7.6
Identities = 18/82 (21%), Positives = 41/82 (50%), Gaps = 6/82 (7%)
Query: 89 LQELALAPCHE------WLSDEDLVPVLARNPQLRSVALGGCGQLSRRALGALAEGCPRL 142
L+EL+++ C+ ++D + + A+ L + + GC L+ + L L GC +L
Sbjct: 556 LKELSVSECYRITDDGIQITDSAMEMLSAKCHYLHILDISGCVLLTDQILEDLQIGCKQL 615
Query: 143 QRLSLAHCDWVDGLALRGLADR 164
+ L + +C + A + ++ +
Sbjct: 616 RILKMQYCTNISKKAAQRMSSK 637
>gi|14249170 S-phase kinase-associated protein 2 isoform 2 [Homo
sapiens]
Length = 410
Score = 53.5 bits (127), Expect = 2e-07
Identities = 42/169 (24%), Positives = 83/169 (49%), Gaps = 4/169 (2%)
Query: 109 VLARNPQLRSVALGGCGQLSRRALGALAEGCPRLQRLSLAHCDWVDGLALRGLADRCPAL 168
+L++ +L++++L G +LS + LA+ L RL+L+ C AL+ L C L
Sbjct: 201 ILSQCSKLQNLSLEGL-RLSDPIVNTLAKNS-NLVRLNLSGCSGFSEFALQTLLSSCSRL 258
Query: 169 EELDLTACRQLKDEAIVYLAQRRGAGLRSLSLA-VNANVGDAAVQELARNCPELHHLDLT 227
+EL+L+ C ++ + + L+L+ N+ + + L R CP L HLDL+
Sbjct: 259 DELNLSWCFDFTEKHVQVAVAHVSETITQLNLSGYRKNLQKSDLSTLVRRCPNLVHLDLS 318
Query: 228 GCLRVGSDGVRTLAEYCPVLRSLRVRHCHHVAESSLSRLRKRGVDIDVE 276
+ + +D + + L+ L + C+ + +L + + GV I ++
Sbjct: 319 DSVMLKNDCFQEFFQ-LNYLQHLSLSRCYDIIPETLLLVTRAGVRIRLD 366
>gi|157168349 F-box and leucine-rich repeat protein 19 [Homo
sapiens]
Length = 694
Score = 52.0 bits (123), Expect = 6e-07
Identities = 65/231 (28%), Positives = 92/231 (39%), Gaps = 40/231 (17%)
Query: 74 IPRAALARLLRDAEGLQELALAP--CH---EWLSDEDLVPV--LARNPQLRSVALGGCGQ 126
+PRAA R+ + G +EL + C W D+ L P L+R L L G +
Sbjct: 424 LPRAAWLRVFQHL-GPRELCICMRVCRTWSRWCYDKRLWPRMDLSRRKSLTPPMLSGVVR 482
Query: 127 LSRRALGALAEGCPR------------LQRLSLAHCDWVDGLALRGLADRCPALEELDLT 174
RAL G + LQ L L+ C W+ AL PAL LDL
Sbjct: 483 RQPRALDLSWTGVSKKQLMWLLNRLQGLQELVLSGCSWLSVSALGSAP--LPALRLLDLR 540
Query: 175 ACRQLKDEAIVYL-------------AQRRGAGLRSLSLAVNANVGDAAVQELARNCPEL 221
+KD + L ++ R G+ L LA + DA+++ L R+ P+L
Sbjct: 541 WIEDVKDSQLRELLLPPPDTKPGQTESRGRLQGVAELRLA-GLELTDASLRLLLRHAPQL 599
Query: 222 HHLDLTGCLRVGSDGVRTLAEYCPVLRS----LRVRHCHHVAESSLSRLRK 268
LDL+ C VG V L LR L + CH + + L R+
Sbjct: 600 SALDLSHCAHVGDPSVHLLTAPTSPLRETLVHLNLAGCHRLTDHCLPLFRR 650
Score = 52.0 bits (123), Expect = 6e-07
Identities = 58/188 (30%), Positives = 82/188 (43%), Gaps = 23/188 (12%)
Query: 101 LSDEDLVPVLARNPQLRSVALGGCGQLSRRALGALAEGCPRLQRLSLAHCDWVDGLALRG 160
+S + L+ +L R L+ + L GC LS ALG+ P L+ L L + V LR
Sbjct: 495 VSKKQLMWLLNRLQGLQELVLSGCSWLSVSALGSAP--LPALRLLDLRWIEDVKDSQLRE 552
Query: 161 LA--------------DRCPALEELDLTACRQLKDEAIVYLAQRRGAGLRSLSLAVNANV 206
L R + EL L +L D A + L R L +L L+ A+V
Sbjct: 553 LLLPPPDTKPGQTESRGRLQGVAELRLAGL-ELTD-ASLRLLLRHAPQLSALDLSHCAHV 610
Query: 207 GDAAVQELARNCPELH----HLDLTGCLRVGSDGVRTLAEYCPVLRSLRVRHCHHVAESS 262
GD +V L L HL+L GC R+ +D L CP LR L +R C ++ +
Sbjct: 611 GDPSVHLLTAPTSPLRETLVHLNLAGCHRL-TDHCLPLFRRCPRLRRLDLRSCRQLSPEA 669
Query: 263 LSRLRKRG 270
+RL G
Sbjct: 670 CARLAAAG 677
Score = 46.2 bits (108), Expect = 3e-05
Identities = 63/210 (30%), Positives = 86/210 (40%), Gaps = 29/210 (13%)
Query: 1 MEPPMEPSGGEQEPGAVRFLDLPWEDVL---LPHVLNRVPLRQLLRLQRVS-RAFRSLVQ 56
+ PPM ++P R LDL W V L +LNR+ Q L L S + +L
Sbjct: 472 LTPPMLSGVVRRQP---RALDLSWTGVSKKQLMWLLNRLQGLQELVLSGCSWLSVSALGS 528
Query: 57 LHLAGLRRFDAAQVGPQIPRAALARLLRDA--------------EGLQELALAPCHEWLS 102
L LR D + + + L LL +G+ EL LA L+
Sbjct: 529 APLPALRLLDLRWI-EDVKDSQLRELLLPPPDTKPGQTESRGRLQGVAELRLAGLE--LT 585
Query: 103 DEDLVPVLARNPQLRSVALGGCGQLSRRALGALAEGCPRLQR----LSLAHCDWVDGLAL 158
D L +L PQL ++ L C + ++ L L+ L+LA C + L
Sbjct: 586 DASLRLLLRHAPQLSALDLSHCAHVGDPSVHLLTAPTSPLRETLVHLNLAGCHRLTDHCL 645
Query: 159 RGLADRCPALEELDLTACRQLKDEAIVYLA 188
L RCP L LDL +CRQL EA LA
Sbjct: 646 P-LFRRCPRLRRLDLRSCRQLSPEACARLA 674
Score = 44.7 bits (104), Expect = 1e-04
Identities = 64/206 (31%), Positives = 87/206 (42%), Gaps = 36/206 (17%)
Query: 63 RRFDAAQVGPQIPRAALARLLRDAEGLQELALAPCHEWLSDEDL----VPVL-------- 110
R D + G + + L LL +GLQEL L+ C WLS L +P L
Sbjct: 486 RALDLSWTG--VSKKQLMWLLNRLQGLQELVLSGC-SWLSVSALGSAPLPALRLLDLRWI 542
Query: 111 --ARNPQLRSVALGGC----GQL-SRRALGALAEGCPRLQRLSLAHCDWVDGLALRGLAD 163
++ QLR + L GQ SR L +AE L LA + D +LR L
Sbjct: 543 EDVKDSQLRELLLPPPDTKPGQTESRGRLQGVAE-------LRLAGLELTDA-SLRLLLR 594
Query: 164 RCPALEELDLTACRQLKDEAIVYLAQRRGAGLRS----LSLAVNANVGDAAVQELARNCP 219
P L LDL+ C + D + V+L + LR L+LA + D + L R CP
Sbjct: 595 HAPQLSALDLSHCAHVGDPS-VHLLTAPTSPLRETLVHLNLAGCHRLTDHCLP-LFRRCP 652
Query: 220 ELHHLDLTGCLRVGSDGVRTLAEYCP 245
L LDL C ++ + LA P
Sbjct: 653 RLRRLDLRSCRQLSPEACARLAAAGP 678
Score = 36.2 bits (82), Expect = 0.036
Identities = 50/154 (32%), Positives = 63/154 (40%), Gaps = 37/154 (24%)
Query: 16 AVRFLDLPW-EDVLLPHVLNRVPLRQLLRL-------QRVSRA-FRSLVQLHLAGLRRFD 66
A+R LDL W EDV LR+LL Q SR + + +L LAGL D
Sbjct: 533 ALRLLDLRWIEDV------KDSQLRELLLPPPDTKPGQTESRGRLQGVAELRLAGLELTD 586
Query: 67 AA-----QVGPQIPRAALARLLRDA---------------EGLQELALAPCHEWLSDEDL 106
A+ + PQ+ L+ E L L LA CH L+D L
Sbjct: 587 ASLRLLLRHAPQLSALDLSHCAHVGDPSVHLLTAPTSPLRETLVHLNLAGCHR-LTDHCL 645
Query: 107 VPVLARNPQLRSVALGGCGQLSRRALGALAEGCP 140
P+ R P+LR + L C QLS A LA P
Sbjct: 646 -PLFRRCPRLRRLDLRSCRQLSPEACARLAAAGP 678
>gi|16306595 S-phase kinase-associated protein 2 isoform 1 [Homo
sapiens]
Length = 424
Score = 49.7 bits (117), Expect = 3e-06
Identities = 50/177 (28%), Positives = 81/177 (45%), Gaps = 6/177 (3%)
Query: 77 AALARLLRDAEGLQELALAPCHEWLSDEDLVPVLARNPQLRSVALGGCGQLSRRALGALA 136
+ L +L LQ L+L LSD +V LA+N L + L GC S AL L
Sbjct: 196 STLHGILSQCSKLQNLSLEGLR--LSDP-IVNTLAKNSNLVRLNLSGCSGFSEFALQTLL 252
Query: 137 EGCPRLQRLSLAHC-DWVDGLALRGLADRCPALEELDLTACRQLKDEAIVYLAQRRGAGL 195
C RL L+L+ C D+ + +A + +L+L+ R+ ++ + RR L
Sbjct: 253 SSCSRLDELNLSWCFDFTEKHVQVAVAHVSETITQLNLSGYRKNLQKSDLSTLVRRCPNL 312
Query: 196 RSLSLAVNANVGDAAVQELARNCPELHHLDLTGCLRVGSDGVRTLAEYCPVLRSLRV 252
L L+ + + + QE + L HL L+ C + + + L E P L++L+V
Sbjct: 313 VHLDLSDSVMLKNDCFQEFFQ-LNYLQHLSLSRCYDIIPETLLELGE-IPTLKTLQV 367
>gi|164663798 antagonist of mitotic exit network 1 homolog [Homo
sapiens]
Length = 258
Score = 48.5 bits (114), Expect = 7e-06
Identities = 34/130 (26%), Positives = 59/130 (45%), Gaps = 2/130 (1%)
Query: 101 LSDEDLVPVLARNPQLRSVALGGCGQLSRRALGALAEGCPRLQRLSLAHCDWVDGLALRG 160
++ E + V + L +L C L+ + ALA C L+ + L C + ++L
Sbjct: 102 VTSEGIKAVASSCSYLHEASLKRCCNLTDEGVVALALNCQLLKIIDLGGCLSITDVSLHA 161
Query: 161 LADRCPALEELDLTACRQLKDEAIVYLAQRRGA-GLRSLSLAVNANVGDAAVQELARNCP 219
L CP L+ +D +A Q+ D ++ L A L + + N+ D AV+ + CP
Sbjct: 162 LGKNCPFLQCVDFSA-TQVSDSGVIALVSGPCAKKLEEIHMGHCVNLTDGAVEAVLTYCP 220
Query: 220 ELHHLDLTGC 229
++ L GC
Sbjct: 221 QIRILLFHGC 230
Score = 45.8 bits (107), Expect = 5e-05
Identities = 36/113 (31%), Positives = 49/113 (43%), Gaps = 7/113 (6%)
Query: 140 PRLQRLSLAHCDWVDGLALRGLADRCPALEELDLTACR----QLKDEAIVYLAQRRGAGL 195
P +Q L L CD D L C L++L+L A + + E I +A L
Sbjct: 61 PEVQTLDLRSCDISDAALLH--LSNCRKLKKLNLNASKGNRVSVTSEGIKAVASSCSY-L 117
Query: 196 RSLSLAVNANVGDAAVQELARNCPELHHLDLTGCLRVGSDGVRTLAEYCPVLR 248
SL N+ D V LA NC L +DL GCL + + L + CP L+
Sbjct: 118 HEASLKRCCNLTDEGVVALALNCQLLKIIDLGGCLSITDVSLHALGKNCPFLQ 170
Score = 44.7 bits (104), Expect = 1e-04
Identities = 30/107 (28%), Positives = 54/107 (50%), Gaps = 7/107 (6%)
Query: 166 PALEELDLTACRQLKDEAIVYLAQRRGAGLRSLSLAVN----ANVGDAAVQELARNCPEL 221
P ++ LDL +C + D A+++L+ R L+ L+L + +V ++ +A +C L
Sbjct: 61 PEVQTLDLRSC-DISDAALLHLSNCRK--LKKLNLNASKGNRVSVTSEGIKAVASSCSYL 117
Query: 222 HHLDLTGCLRVGSDGVRTLAEYCPVLRSLRVRHCHHVAESSLSRLRK 268
H L C + +GV LA C +L+ + + C + + SL L K
Sbjct: 118 HEASLKRCCNLTDEGVVALALNCQLLKIIDLGGCLSITDVSLHALGK 164
Score = 33.9 bits (76), Expect = 0.18
Identities = 30/131 (22%), Positives = 50/131 (38%), Gaps = 28/131 (21%)
Query: 89 LQELALAPCHEWLSDEDLVPVLARNPQLRSVALGGCGQLSRRALGALAEGCP-------- 140
L E +L C L+DE +V + L+ + LGGC ++ +L AL + CP
Sbjct: 117 LHEASLKRCCN-LTDEGVVALALNCQLLKIIDLGGCLSITDVSLHALGKNCPFLQCVDFS 175
Query: 141 -------------------RLQRLSLAHCDWVDGLALRGLADRCPALEELDLTACRQLKD 181
+L+ + + HC + A+ + CP + L C + D
Sbjct: 176 ATQVSDSGVIALVSGPCAKKLEEIHMGHCVNLTDGAVEAVLTYCPQIRILLFHGCPLITD 235
Query: 182 EAIVYLAQRRG 192
+ L Q G
Sbjct: 236 HSREVLEQLVG 246
>gi|54112382 F-box and leucine-rich repeat protein 10 isoform a [Homo
sapiens]
Length = 1336
Score = 46.2 bits (108), Expect = 3e-05
Identities = 42/144 (29%), Positives = 63/144 (43%), Gaps = 16/144 (11%)
Query: 127 LSRRALGALAEGCPRLQRLSLAHCDWVDGLALRGLADRCPALEELDLTACRQLKDEAIVY 186
+S++ L L P L+ L L+ C W+ AL + CP L LD+ LKD
Sbjct: 1136 ISKKQLSWLINRLPGLRDLVLSGCSWIAVSAL--CSSSCPLLRTLDVQWVEGLKD----- 1188
Query: 187 LAQRRGAGLRSLSLAVNANVGDAAVQELARNCPELHHLDLTGCLRVGSDGVRTLAEYCPV 246
AQ R LS + G + RN EL L G L + +R + + P+
Sbjct: 1189 -AQMRDL----LSPPTDNRPGQMDNRSKLRNIVELR---LAG-LDITDASLRLIIRHMPL 1239
Query: 247 LRSLRVRHCHHVAESSLSRLRKRG 270
L L + +C+HV + S++ L G
Sbjct: 1240 LSKLHLSYCNHVTDQSINLLTAVG 1263
Score = 34.7 bits (78), Expect = 0.11
Identities = 41/181 (22%), Positives = 67/181 (37%), Gaps = 51/181 (28%)
Query: 101 LSDEDLVPVLARNPQLRSVALGGCGQLSRRALGALAEGCPRLQRLSLAHCDWVDGL---- 156
+S + L ++ R P LR + L GC ++ AL + CP L+ L + WV+GL
Sbjct: 1136 ISKKQLSWLINRLPGLRDLVLSGCSWIAVSAL--CSSSCPLLRTLDV---QWVEGLKDAQ 1190
Query: 157 --------------------------------------ALRGLADRCPALEELDLTACRQ 178
+LR + P L +L L+ C
Sbjct: 1191 MRDLLSPPTDNRPGQMDNRSKLRNIVELRLAGLDITDASLRLIIRHMPLLSKLHLSYCNH 1250
Query: 179 LKDEAIVYLAQ---RRGAGLRSLSLAVNANVGDAAVQELARNCPELHHLDLTGCLRVGSD 235
+ D++I L L ++L+ V D + R C + H+DL C +V +
Sbjct: 1251 VTDQSINLLTAVGTTTRDSLTEINLSDCNKVTDQCLSFFKR-CGNICHIDLRYCKQVTKE 1309
Query: 236 G 236
G
Sbjct: 1310 G 1310
>gi|54112380 F-box and leucine-rich repeat protein 10 isoform b [Homo
sapiens]
Length = 1265
Score = 46.2 bits (108), Expect = 3e-05
Identities = 42/144 (29%), Positives = 63/144 (43%), Gaps = 16/144 (11%)
Query: 127 LSRRALGALAEGCPRLQRLSLAHCDWVDGLALRGLADRCPALEELDLTACRQLKDEAIVY 186
+S++ L L P L+ L L+ C W+ AL + CP L LD+ LKD
Sbjct: 1067 ISKKQLSWLINRLPGLRDLVLSGCSWIAVSAL--CSSSCPLLRTLDVQWVEGLKD----- 1119
Query: 187 LAQRRGAGLRSLSLAVNANVGDAAVQELARNCPELHHLDLTGCLRVGSDGVRTLAEYCPV 246
AQ R LS + G + RN EL L G L + +R + + P+
Sbjct: 1120 -AQMRDL----LSPPTDNRPGQMDNRSKLRNIVELR---LAG-LDITDASLRLIIRHMPL 1170
Query: 247 LRSLRVRHCHHVAESSLSRLRKRG 270
L L + +C+HV + S++ L G
Sbjct: 1171 LSKLHLSYCNHVTDQSINLLTAVG 1194
Score = 35.4 bits (80), Expect = 0.062
Identities = 44/200 (22%), Positives = 74/200 (37%), Gaps = 54/200 (27%)
Query: 101 LSDEDLVPVLARNPQLRSVALGGCGQLSRRALGALAEGCPRLQRLSLAHCDWVDGL---- 156
+S + L ++ R P LR + L GC ++ AL + CP L+ L + WV+GL
Sbjct: 1067 ISKKQLSWLINRLPGLRDLVLSGCSWIAVSAL--CSSSCPLLRTLDV---QWVEGLKDAQ 1121
Query: 157 --------------------------------------ALRGLADRCPALEELDLTACRQ 178
+LR + P L +L L+ C
Sbjct: 1122 MRDLLSPPTDNRPGQMDNRSKLRNIVELRLAGLDITDASLRLIIRHMPLLSKLHLSYCNH 1181
Query: 179 LKDEAIVYLAQ---RRGAGLRSLSLAVNANVGDAAVQELARNCPELHHLDLTGCLRVGSD 235
+ D++I L L ++L+ V D + R C + H+DL C +V +
Sbjct: 1182 VTDQSINLLTAVGTTTRDSLTEINLSDCNKVTDQCLSFFKR-CGNICHIDLRYCKQVTKE 1240
Query: 236 GVRTLAEYCPVLRSLRVRHC 255
G ++ + S + R C
Sbjct: 1241 GCE---QFIAEMSSFQGRSC 1257
>gi|16306576 F-box and leucine-rich repeat protein 6 isoform 1 [Homo
sapiens]
Length = 539
Score = 44.7 bits (104), Expect = 1e-04
Identities = 38/125 (30%), Positives = 56/125 (44%), Gaps = 5/125 (4%)
Query: 132 LGALAEGCPRLQRLSLAHCDWVDGLALRGLADRCPALEELDLTACRQLKDEAIVYLAQRR 191
L + E CPRL L L+ C V AL LA C L LDL ++ A+V +
Sbjct: 212 LKLVGECCPRLTFLKLSGCHGVTADALVMLAKACCQLHSLDLQH-SMVESTAVVSFLEEA 270
Query: 192 GAGLRSLSLAVNANVGDAAVQELARNCPELHHLDLTGCLRVGSD----GVRTLAEYCPVL 247
G+ +R L L ++ L CP+L L+++ + S V L + CP L
Sbjct: 271 GSRMRKLWLTYSSQTTAILGALLGSCCPQLQVLEVSTGINRNSIPLQLPVEALQKGCPQL 330
Query: 248 RSLRV 252
+ LR+
Sbjct: 331 QVLRL 335
Score = 42.7 bits (99), Expect = 4e-04
Identities = 45/135 (33%), Positives = 61/135 (45%), Gaps = 12/135 (8%)
Query: 134 ALAEGCPRLQRLSLAHCDWVDGLALRGLA--DRCPALEELDL--TACRQLKDEAIVYLAQ 189
AL +GCP+LQ L L + W+ RG+A P+LEEL L + C + +E + L
Sbjct: 322 ALQKGCPQLQVLRLLNLMWLPKPPGRGVAPGPGFPSLEELCLASSTCNFVSNEVLGRLL- 380
Query: 190 RRGAGLRSLSLAVNANVGDAAVQELARNCPELHHLDLTGCLRVGSDGVRTLAEYCPVLRS 249
LR L L A + A +Q+L E HL L G SD + E P L
Sbjct: 381 HGSPNLRLLDLRGCARITPAGLQDLPCRELEQLHLGLYGT----SDRLTLAKEGSPFLTQ 436
Query: 250 LRVRHCHHVAESSLS 264
+ CH + E LS
Sbjct: 437 ---KWCHTLRELDLS 448
Score = 39.7 bits (91), Expect = 0.003
Identities = 45/154 (29%), Positives = 70/154 (45%), Gaps = 16/154 (10%)
Query: 89 LQELALAPCH-EWLSDEDLVPVLARNPQLRSVALGGCGQLSRRALGALAEGCPRLQRLSL 147
L+EL LA ++S+E L +L +P LR + L GC +++ L L C L++L L
Sbjct: 358 LEELCLASSTCNFVSNEVLGRLLHGSPNLRLLDLRGCARITPAGLQDLP--CRELEQLHL 415
Query: 148 AHCDWVDGLALRGLADR------CPALEELDLT----ACRQLKDEAIVYLAQRRGA--GL 195
D L L C L ELDL+ + + L+ +L+ G+ L
Sbjct: 416 GLYGTSDRLTLAKEGSPFLTQKWCHTLRELDLSGQGFSEKDLEQALAAFLSTPGGSHPAL 475
Query: 196 RSLSLAVNANVGDAAVQELARNCPELHHLDLTGC 229
SL+L V + V + +CP L +L+L C
Sbjct: 476 CSLNLR-GTRVTPSTVSSVISSCPGLLYLNLESC 508
Score = 33.9 bits (76), Expect = 0.18
Identities = 24/88 (27%), Positives = 44/88 (50%)
Query: 183 AIVYLAQRRGAGLRSLSLAVNANVGDAAVQELARNCPELHHLDLTGCLRVGSDGVRTLAE 242
++ +L R + L+ L+L + ++ + CP L L L+GC V +D + LA+
Sbjct: 184 SLEWLMPNRFSQLQRLTLIHWKSQVHPVLKLVGECCPRLTFLKLSGCHGVTADALVMLAK 243
Query: 243 YCPVLRSLRVRHCHHVAESSLSRLRKRG 270
C L SL ++H + + +S L + G
Sbjct: 244 ACCQLHSLDLQHSMVESTAVVSFLEEAG 271
>gi|61742136 F-box and leucine-rich repeat protein 6 isoform 2 [Homo
sapiens]
Length = 533
Score = 44.3 bits (103), Expect = 1e-04
Identities = 37/122 (30%), Positives = 55/122 (45%), Gaps = 5/122 (4%)
Query: 135 LAEGCPRLQRLSLAHCDWVDGLALRGLADRCPALEELDLTACRQLKDEAIVYLAQRRGAG 194
+ E CPRL L L+ C V AL LA C L LDL ++ A+V + G+
Sbjct: 209 VGECCPRLTFLKLSGCHGVTADALVMLAKACCQLHSLDLQH-SMVESTAVVSFLEEAGSR 267
Query: 195 LRSLSLAVNANVGDAAVQELARNCPELHHLDLTGCLRVGSD----GVRTLAEYCPVLRSL 250
+R L L ++ L CP+L L+++ + S V L + CP L+ L
Sbjct: 268 MRKLWLTYSSQTTAILGALLGSCCPQLQVLEVSTGINRNSIPLQLPVEALQKGCPQLQVL 327
Query: 251 RV 252
R+
Sbjct: 328 RL 329
Score = 42.7 bits (99), Expect = 4e-04
Identities = 45/135 (33%), Positives = 61/135 (45%), Gaps = 12/135 (8%)
Query: 134 ALAEGCPRLQRLSLAHCDWVDGLALRGLA--DRCPALEELDL--TACRQLKDEAIVYLAQ 189
AL +GCP+LQ L L + W+ RG+A P+LEEL L + C + +E + L
Sbjct: 316 ALQKGCPQLQVLRLLNLMWLPKPPGRGVAPGPGFPSLEELCLASSTCNFVSNEVLGRLL- 374
Query: 190 RRGAGLRSLSLAVNANVGDAAVQELARNCPELHHLDLTGCLRVGSDGVRTLAEYCPVLRS 249
LR L L A + A +Q+L E HL L G SD + E P L
Sbjct: 375 HGSPNLRLLDLRGCARITPAGLQDLPCRELEQLHLGLYGT----SDRLTLAKEGSPFLTQ 430
Query: 250 LRVRHCHHVAESSLS 264
+ CH + E LS
Sbjct: 431 ---KWCHTLRELDLS 442
Score = 39.7 bits (91), Expect = 0.003
Identities = 45/154 (29%), Positives = 70/154 (45%), Gaps = 16/154 (10%)
Query: 89 LQELALAPCH-EWLSDEDLVPVLARNPQLRSVALGGCGQLSRRALGALAEGCPRLQRLSL 147
L+EL LA ++S+E L +L +P LR + L GC +++ L L C L++L L
Sbjct: 352 LEELCLASSTCNFVSNEVLGRLLHGSPNLRLLDLRGCARITPAGLQDLP--CRELEQLHL 409
Query: 148 AHCDWVDGLALRGLADR------CPALEELDLT----ACRQLKDEAIVYLAQRRGA--GL 195
D L L C L ELDL+ + + L+ +L+ G+ L
Sbjct: 410 GLYGTSDRLTLAKEGSPFLTQKWCHTLRELDLSGQGFSEKDLEQALAAFLSTPGGSHPAL 469
Query: 196 RSLSLAVNANVGDAAVQELARNCPELHHLDLTGC 229
SL+L V + V + +CP L +L+L C
Sbjct: 470 CSLNLR-GTRVTPSTVSSVISSCPGLLYLNLESC 502
Score = 33.5 bits (75), Expect = 0.23
Identities = 19/53 (35%), Positives = 29/53 (54%)
Query: 218 CPELHHLDLTGCLRVGSDGVRTLAEYCPVLRSLRVRHCHHVAESSLSRLRKRG 270
CP L L L+GC V +D + LA+ C L SL ++H + + +S L + G
Sbjct: 213 CPRLTFLKLSGCHGVTADALVMLAKACCQLHSLDLQHSMVESTAVVSFLEEAG 265
>gi|22547146 F-box and leucine-rich repeat protein 8 [Homo sapiens]
Length = 374
Score = 42.7 bits (99), Expect = 4e-04
Identities = 30/66 (45%), Positives = 36/66 (54%), Gaps = 7/66 (10%)
Query: 188 AQRRGAGLRSLSLAVNANVGDAAVQELARNCPELHHLDLTGCLRVGSDG---VRTLAEYC 244
+Q R LR LS ++ DA V + AR+CPELH L L VGS G V L E C
Sbjct: 135 SQLRHLDLRRLSFTLD----DALVLQAARSCPELHSLFLDNSTLVGSVGPGSVLELLEAC 190
Query: 245 PVLRSL 250
P LR+L
Sbjct: 191 PRLRAL 196
Score = 30.8 bits (68), Expect = 1.5
Identities = 24/73 (32%), Positives = 31/73 (42%), Gaps = 3/73 (4%)
Query: 157 ALRGLADRCPALEELDLTACRQLKDEAIVYLAQRRGAGLRSLSL---AVNANVGDAAVQE 213
A+ + L LDL D+A+V A R L SL L + +VG +V E
Sbjct: 126 AVHAVCGAASQLRHLDLRRLSFTLDDALVLQAARSCPELHSLFLDNSTLVGSVGPGSVLE 185
Query: 214 LARNCPELHHLDL 226
L CP L L L
Sbjct: 186 LLEACPRLRALGL 198
>gi|21264320 NLR family, pyrin domain containing 6 [Homo sapiens]
Length = 892
Score = 40.4 bits (93), Expect = 0.002
Identities = 47/137 (34%), Positives = 66/137 (48%), Gaps = 16/137 (11%)
Query: 89 LQELALAPCHEWLSD---EDLVPVLARNPQLRSVALGGCGQLSRRALGALAEGCP----R 141
L L L+ C L D DL L P L + L +LS L L+EG R
Sbjct: 730 LSSLTLSHCK--LPDAVCRDLSEALRAAPALTELGLLH-NRLSEAGLRMLSEGLAWPQCR 786
Query: 142 LQRLSLAHCDWVDGLA-LRGLADRCPALEELDLTACRQLKDEAIVYLA---QRRGAGLRS 197
+Q + + D GL L G+ + PAL LDL+ C QL + YL Q +G GL++
Sbjct: 787 VQTVRVQLPDPQRGLQYLVGMLRQSPALTTLDLSGC-QLPAPMVTYLCAVLQHQGCGLQT 845
Query: 198 LSLAVNANVGDAAVQEL 214
LSLA + + + ++QEL
Sbjct: 846 LSLA-SVELSEQSLQEL 861
>gi|24308207 leucine rich repeat containing 47 [Homo sapiens]
Length = 583
Score = 37.7 bits (86), Expect = 0.012
Identities = 58/180 (32%), Positives = 73/180 (40%), Gaps = 33/180 (18%)
Query: 67 AAQVGPQIPRAALAR------LLRDAEGLQELALAPCHEWLSDEDLVPVLARNPQLRSVA 120
AA V P LA LL GL+E A + L P L P L +
Sbjct: 3 AAAVSESWPELELAERERRRELLLTGPGLEERVRA------AGGQLPPRLFTLPLLHYLE 56
Query: 121 LGGCGQLSRRALGALAEGCPRLQRLSLAHCDWVDGLALRGLADRCPALEELDLTACRQLK 180
+ GCG L G LA+G P+L L L GL+ PAL LDL+
Sbjct: 57 VSGCGSLRAPGPG-LAQGLPQLHSLVLRRNALGPGLSPE--LGPLPALRVLDLSG----- 108
Query: 181 DEAIVYLAQRRGAG---------LRSLSLAVNANVGDAAVQELARNCPELHHLDLTG-CL 230
A+ L +G G L+SL+L+ N A +LAR P L L+LTG CL
Sbjct: 109 -NALEALPPGQGLGPAEPPGLPQLQSLNLSGNRLRELPA--DLARCAPRLQSLNLTGNCL 165
>gi|8922303 ATP5S-like [Homo sapiens]
Length = 257
Score = 37.0 bits (84), Expect = 0.021
Identities = 23/80 (28%), Positives = 34/80 (42%), Gaps = 3/80 (3%)
Query: 142 LQRLSLAHCDWVDGLALRGLADRCPALEELDLTACRQLKDEAIV---YLAQRRGAGLRSL 198
LQ LSL C VD L L +L+EL L C ++ + + +L R + L
Sbjct: 150 LQSLSLQRCSHVDDWCLSRLYPLADSLQELSLAGCPRISERGLACLHHLQNLRRLDISDL 209
Query: 199 SLAVNANVGDAAVQELARNC 218
N + V+E+ NC
Sbjct: 210 PAVSNPGLTQILVEEMLPNC 229
Score = 28.1 bits (61), Expect = 9.9
Identities = 21/72 (29%), Positives = 33/72 (45%), Gaps = 1/72 (1%)
Query: 195 LRSLSLAVNANVGDAAVQELARNCPELHHLDLTGCLRVGSDGVRTLAEYCPVLRSLRVRH 254
L+SLSL ++V D + L L L L GC R+ G+ L + LR L +
Sbjct: 150 LQSLSLQRCSHVDDWCLSRLYPLADSLQELSLAGCPRISERGLACL-HHLQNLRRLDISD 208
Query: 255 CHHVAESSLSRL 266
V+ L+++
Sbjct: 209 LPAVSNPGLTQI 220
>gi|194440719 chondroadherin-like [Homo sapiens]
Length = 762
Score = 36.6 bits (83), Expect = 0.028
Identities = 60/205 (29%), Positives = 78/205 (38%), Gaps = 40/205 (19%)
Query: 38 LRQLLRLQRVSRAFRSLVQLHLAGLRRFDAAQVGPQIPRAALARLLRDAEGLQEL----- 92
L +LL L S R L Q L GL +L RL + L+EL
Sbjct: 109 LGRLLLLNLASNHLRELPQEALDGL--------------GSLRRLELEGNALEELRPGTF 154
Query: 93 ----ALAPCHEWLSDEDLVPVLARNPQLRSVALGGCGQLSRRALGALAE----GCPRLQR 144
ALA + + +P +A LR L +LS AL LA G P L+R
Sbjct: 155 GALGALATLNLAHNALVYLPAMAFQGLLRVRWL----RLSHNALSVLAPEALAGLPALRR 210
Query: 145 LSLAHCDWVDGLALRGLADRCPALEELDLTACRQLKDEAIVYLAQRRGAGLRSL-SLAVN 203
LSL H + AL G P L + A +L + Y + G L L L ++
Sbjct: 211 LSLHHNELQ---ALPG-----PVLSQARGLARLELGHNPLTYAGEEDGLALPGLRELLLD 262
Query: 204 ANVGDAAVQELARNCPELHHLDLTG 228
A +CP LH LDL G
Sbjct: 263 GGALQALGPRAFAHCPRLHTLDLRG 287
>gi|16306580 F-box and leucine-rich repeat protein 11 [Homo sapiens]
Length = 1162
Score = 36.2 bits (82), Expect = 0.036
Identities = 40/146 (27%), Positives = 57/146 (39%), Gaps = 22/146 (15%)
Query: 127 LSRRALGALAEGCPRLQRLSLAHCDWVDGLALRGLADRCPALEELDLTACRQLKDEAIVY 186
+S++ L L P L+ L LA C W AL CP L LDL +KD I
Sbjct: 964 ISKKQLTWLVNRLPGLKDLLLAGCSWSAVSALS--TSSCPLLRTLDLRWAVGIKDPQIRD 1021
Query: 187 LAQRRGAGLRSLSLAVNANVGDAAVQELARNCPE--LHHLDLTGCLRVGSDGVRTLAEYC 244
L L A+ + RN + L LD+T +R + +
Sbjct: 1022 L------------LTPPADKPGQDNRSKLRNMTDFRLAGLDITDAT------LRLIIRHM 1063
Query: 245 PVLRSLRVRHCHHVAESSLSRLRKRG 270
P+L L + HC H+ + S + L G
Sbjct: 1064 PLLSRLDLSHCSHLTDQSSNLLTAVG 1089
>gi|16306574 F-box and leucine-rich repeat protein 5 isoform 2 [Homo
sapiens]
Length = 565
Score = 36.2 bits (82), Expect = 0.036
Identities = 22/72 (30%), Positives = 34/72 (47%), Gaps = 2/72 (2%)
Query: 189 QRRGAGLRSLSLAVNANVGDAAVQ--ELARNCPELHHLDLTGCLRVGSDGVRTLAEYCPV 246
Q G L LSL+ + D ++ L P L HL+L+GCL + G++ L CP
Sbjct: 468 QETGRVLLFLSLSGCYQITDHGLRVLTLGGGLPYLEHLNLSGCLTITGAGLQDLVSACPS 527
Query: 247 LRSLRVRHCHHV 258
L +C ++
Sbjct: 528 LNDEYFYYCDNI 539
Score = 35.0 bits (79), Expect = 0.081
Identities = 36/159 (22%), Positives = 59/159 (37%), Gaps = 38/159 (23%)
Query: 98 HEWLSDEDLVPVLARNPQLRSVALGGCGQLSRRALGALAEGC-----PRLQRLSLAHCDW 152
HEW D D+ + S+A+ Q+ +R L L ++ L LA+
Sbjct: 160 HEWDEDADIDE--SEESAEESIAIS-IAQMEKRLLHGLIHNVLPYVGTSVKTLVLAYSSA 216
Query: 153 VDGLALRGLADRCPALEELDLTACRQLKDEAIVYLAQRRGAGLRSLSLAVNANVGDAAVQ 212
V +R + + CP LE LDLT ++ D+A
Sbjct: 217 VSSKMVRQILELCPNLEHLDLT----------------------------QTDISDSAFD 248
Query: 213 ELA--RNCPELHHLDLTGCLRVGSDGVRTLAEYCPVLRS 249
+ C L HLDL+GC ++ + ++ +L S
Sbjct: 249 SWSWLGCCQSLRHLDLSGCEKITDVALEKISRALGILTS 287
Score = 35.0 bits (79), Expect = 0.081
Identities = 18/54 (33%), Positives = 29/54 (53%), Gaps = 2/54 (3%)
Query: 119 VALGGCGQLSRRALGALA--EGCPRLQRLSLAHCDWVDGLALRGLADRCPALEE 170
++L GC Q++ L L G P L+ L+L+ C + G L+ L CP+L +
Sbjct: 477 LSLSGCYQITDHGLRVLTLGGGLPYLEHLNLSGCLTITGAGLQDLVSACPSLND 530
Score = 34.3 bits (77), Expect = 0.14
Identities = 20/78 (25%), Positives = 38/78 (48%), Gaps = 1/78 (1%)
Query: 192 GAGLRSLSLAVNANVGDAAVQELARNCPELHHLDLTGC-LRVGSDGVRTLAEYCPVLRSL 250
G +++L LA ++ V V+++ CP L HLDLT + + + C LR L
Sbjct: 203 GTSVKTLVLAYSSAVSSKMVRQILELCPNLEHLDLTQTDISDSAFDSWSWLGCCQSLRHL 262
Query: 251 RVRHCHHVAESSLSRLRK 268
+ C + + +L ++ +
Sbjct: 263 DLSGCEKITDVALEKISR 280
>gi|16306572 F-box and leucine-rich repeat protein 5 isoform 1 [Homo
sapiens]
Length = 691
Score = 36.2 bits (82), Expect = 0.036
Identities = 22/72 (30%), Positives = 34/72 (47%), Gaps = 2/72 (2%)
Query: 189 QRRGAGLRSLSLAVNANVGDAAVQ--ELARNCPELHHLDLTGCLRVGSDGVRTLAEYCPV 246
Q G L LSL+ + D ++ L P L HL+L+GCL + G++ L CP
Sbjct: 594 QETGRVLLFLSLSGCYQITDHGLRVLTLGGGLPYLEHLNLSGCLTITGAGLQDLVSACPS 653
Query: 247 LRSLRVRHCHHV 258
L +C ++
Sbjct: 654 LNDEYFYYCDNI 665
Score = 35.0 bits (79), Expect = 0.081
Identities = 36/159 (22%), Positives = 59/159 (37%), Gaps = 38/159 (23%)
Query: 98 HEWLSDEDLVPVLARNPQLRSVALGGCGQLSRRALGALAEGC-----PRLQRLSLAHCDW 152
HEW D D+ + S+A+ Q+ +R L L ++ L LA+
Sbjct: 286 HEWDEDADIDE--SEESAEESIAIS-IAQMEKRLLHGLIHNVLPYVGTSVKTLVLAYSSA 342
Query: 153 VDGLALRGLADRCPALEELDLTACRQLKDEAIVYLAQRRGAGLRSLSLAVNANVGDAAVQ 212
V +R + + CP LE LDLT ++ D+A
Sbjct: 343 VSSKMVRQILELCPNLEHLDLT----------------------------QTDISDSAFD 374
Query: 213 ELA--RNCPELHHLDLTGCLRVGSDGVRTLAEYCPVLRS 249
+ C L HLDL+GC ++ + ++ +L S
Sbjct: 375 SWSWLGCCQSLRHLDLSGCEKITDVALEKISRALGILTS 413
Score = 35.0 bits (79), Expect = 0.081
Identities = 18/54 (33%), Positives = 29/54 (53%), Gaps = 2/54 (3%)
Query: 119 VALGGCGQLSRRALGALA--EGCPRLQRLSLAHCDWVDGLALRGLADRCPALEE 170
++L GC Q++ L L G P L+ L+L+ C + G L+ L CP+L +
Sbjct: 603 LSLSGCYQITDHGLRVLTLGGGLPYLEHLNLSGCLTITGAGLQDLVSACPSLND 656
Score = 34.3 bits (77), Expect = 0.14
Identities = 20/78 (25%), Positives = 38/78 (48%), Gaps = 1/78 (1%)
Query: 192 GAGLRSLSLAVNANVGDAAVQELARNCPELHHLDLTGC-LRVGSDGVRTLAEYCPVLRSL 250
G +++L LA ++ V V+++ CP L HLDLT + + + C LR L
Sbjct: 329 GTSVKTLVLAYSSAVSSKMVRQILELCPNLEHLDLTQTDISDSAFDSWSWLGCCQSLRHL 388
Query: 251 RVRHCHHVAESSLSRLRK 268
+ C + + +L ++ +
Sbjct: 389 DLSGCEKITDVALEKISR 406
>gi|187608777 NF-kappa-B inhibitor-like protein 2 [Homo sapiens]
Length = 1378
Score = 35.4 bits (80), Expect = 0.062
Identities = 63/208 (30%), Positives = 84/208 (40%), Gaps = 32/208 (15%)
Query: 66 DAAQVGPQIPRAALARLLRDAEGLQELALAPCHEWLSDE---DLVPVLARNPQLRSVALG 122
D AQ+ P L R L+ L+EL LA L D+ +LV L P L + L
Sbjct: 1055 DQAQLTP------LLRALKLHTALRELRLAGNR--LGDKCVAELVAALGTMPSLALLDLS 1106
Query: 123 GCGQLSRRALGALAEGCP------RLQRLSLAHCDWVDGL--ALRGLADRCPALEELDLT 174
L L LA G P L+ L L+ DG +L L CP L L L
Sbjct: 1107 S-NHLGPEGLRQLAMGLPGQATLQSLEELDLSMNPLGDGCGQSLASLLHACPLLSTLRLQ 1165
Query: 175 ACR-----QLKDEAIVYLAQRRGAGLRSLSLAVNANVGDAAVQELARNCP--ELHHLDLT 227
AC L + + A + L++LSL+ NA +G A+ ++ P L HL+L+
Sbjct: 1166 ACGFGPSFFLSHQTALGSAFQDAEHLKTLSLSYNA-LGAPALARTLQSLPAGTLLHLELS 1224
Query: 228 GCLRVGSDGVRTLAEYCPVLRSLRVRHC 255
G L E PV R L C
Sbjct: 1225 SV--AAGKGDSDLME--PVFRYLAKEGC 1248
>gi|157426875 F-box and leucine-rich repeat protein 18 [Homo
sapiens]
Length = 718
Score = 34.7 bits (78), Expect = 0.11
Identities = 50/176 (28%), Positives = 72/176 (40%), Gaps = 18/176 (10%)
Query: 11 EQEPGAVRFLD----LPWEDVLLPHVLNRVPLRQLLRLQRVSRAFRSLVQLHL-AGLRRF 65
+ P A D L + D +L H+L+ VP L + V R R L L L L
Sbjct: 14 DMHPAAAGMADGVHLLGFSDEILLHILSHVPSTDL--ILNVRRTCRKLAALCLDKSLIHT 71
Query: 66 DAAQVGPQIPRAALARLLRD-AEGLQELALAPCHEWLSDEDLVPVLARNPQLRSVALGGC 124
Q Q + +L+++ +Q+L++A C+ WL V +AR L V L GC
Sbjct: 72 VLLQKDYQASEDKVRQLVKEIGREIQQLSMAGCY-WLPG-STVEHVARCRSLVKVNLSGC 129
Query: 125 GQLSRRALGALAEGCPRLQRLSLAHCDWVDGLALRGLADRCPALEELDLTACRQLK 180
S R L++ LQ L D G L+ C A L+ R+LK
Sbjct: 130 HLTSLR----LSKMLSALQHLRSLAIDVSPGFDASQLSSECKA----TLSRVRELK 177
Score = 30.4 bits (67), Expect = 2.0
Identities = 23/77 (29%), Positives = 41/77 (53%), Gaps = 6/77 (7%)
Query: 142 LQRLSLAHCDWVDGLALRGLADRCPALEELDLTACRQLKDEAIVYLAQRRGAGLRSLSLA 201
+Q+LS+A C W+ G + +A RC +L +++L+ C + L++ A SLA
Sbjct: 96 IQQLSMAGCYWLPGSTVEHVA-RCRSLVKVNLSGCHLTS----LRLSKMLSALQHLRSLA 150
Query: 202 VNANVGDAAVQELARNC 218
++ + G A Q L+ C
Sbjct: 151 IDVSPGFDASQ-LSSEC 166
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.324 0.140 0.427
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,304,605
Number of Sequences: 37866
Number of extensions: 460977
Number of successful extensions: 1723
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 25
Number of HSP's successfully gapped in prelim test: 20
Number of HSP's that attempted gapping in prelim test: 1470
Number of HSP's gapped (non-prelim): 130
length of query: 300
length of database: 18,247,518
effective HSP length: 102
effective length of query: 198
effective length of database: 14,385,186
effective search space: 2848266828
effective search space used: 2848266828
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.5 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.