Search of human proteins with 190014578

Search of human proteins with 190014578

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|190014578 suppressor of actin 1 [Homo sapiens]
         (587 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|190014578 suppressor of actin 1 [Homo sapiens]                    1188   0.0  
gi|7662414 inositol polyphosphate-5-phosphatase F [Homo sapiens]      296   3e-80
gi|237757326 synaptojanin 1 isoform d [Homo sapiens]                  206   5e-53
gi|237757312 synaptojanin 1 isoform c [Homo sapiens]                  203   3e-52
gi|237757310 synaptojanin 1 isoform a [Homo sapiens]                  203   3e-52
gi|237757308 synaptojanin 1 isoform b [Homo sapiens]                  203   3e-52
gi|26190608 synaptojanin 2 [Homo sapiens]                             190   4e-48
gi|7662034 Sac domain-containing inositol phosphatase 3 [Homo sa...   175   9e-44
gi|148664197 coiled-coil domain containing 40 [Homo sapiens]           31   3.6  
gi|4507491 thimet oligopeptidase 1 [Homo sapiens]                      30   4.7  
gi|4502827 cholinergic receptor, nicotinic, alpha 4 subunit prec...    30   6.2  
gi|21735548 centrosomal protein 2 [Homo sapiens]                       30   8.1  

>gi|190014578 suppressor of actin 1 [Homo sapiens]
          Length = 587

 Score = 1188 bits (3074), Expect = 0.0
 Identities = 587/587 (100%), Positives = 587/587 (100%)

Query: 1   MATAAYEQLKLHITPEKFYVEACDDGADDVLTIDRVSTEVTLAVKKDVPPSAVTRPIFGI 60
           MATAAYEQLKLHITPEKFYVEACDDGADDVLTIDRVSTEVTLAVKKDVPPSAVTRPIFGI
Sbjct: 1   MATAAYEQLKLHITPEKFYVEACDDGADDVLTIDRVSTEVTLAVKKDVPPSAVTRPIFGI 60

Query: 61  LGTIHLVAGNYLIVITKKIKVGEFFSHVVWKATDFDVLSYKKTMLHLTDIQLQDNKTFLA 120
           LGTIHLVAGNYLIVITKKIKVGEFFSHVVWKATDFDVLSYKKTMLHLTDIQLQDNKTFLA
Sbjct: 61  LGTIHLVAGNYLIVITKKIKVGEFFSHVVWKATDFDVLSYKKTMLHLTDIQLQDNKTFLA 120

Query: 121 MLNHVLNVDGFYFSTTYDLTHTLQRLSNTSPEFQEMSLLERADQRFVWNGHLLRELSAQP 180
           MLNHVLNVDGFYFSTTYDLTHTLQRLSNTSPEFQEMSLLERADQRFVWNGHLLRELSAQP
Sbjct: 121 MLNHVLNVDGFYFSTTYDLTHTLQRLSNTSPEFQEMSLLERADQRFVWNGHLLRELSAQP 180

Query: 181 EVHRFALPVLHGFITMHSCSINGKYFDWILISRRSCFRAGVRYYVRGIDSEGHAANFVET 240
           EVHRFALPVLHGFITMHSCSINGKYFDWILISRRSCFRAGVRYYVRGIDSEGHAANFVET
Sbjct: 181 EVHRFALPVLHGFITMHSCSINGKYFDWILISRRSCFRAGVRYYVRGIDSEGHAANFVET 240

Query: 241 EQIVHYNGSKASFVQTRGSIPVFWSQRPNLKYKPLPQISKVANHMDGFQRHFDSQVIIYG 300
           EQIVHYNGSKASFVQTRGSIPVFWSQRPNLKYKPLPQISKVANHMDGFQRHFDSQVIIYG
Sbjct: 241 EQIVHYNGSKASFVQTRGSIPVFWSQRPNLKYKPLPQISKVANHMDGFQRHFDSQVIIYG 300

Query: 301 KQVIINLINQKGSEKPLEQTFATMVSSLGSGMMRYIAFDFHKECKNMRWDRLSILLDQVA 360
           KQVIINLINQKGSEKPLEQTFATMVSSLGSGMMRYIAFDFHKECKNMRWDRLSILLDQVA
Sbjct: 301 KQVIINLINQKGSEKPLEQTFATMVSSLGSGMMRYIAFDFHKECKNMRWDRLSILLDQVA 360

Query: 361 EMQDELSYFLVDSAGQVVANQEGVFRSNCMDCLDRTNVIQSLLARRSLQAQLQRLGVLHV 420
           EMQDELSYFLVDSAGQVVANQEGVFRSNCMDCLDRTNVIQSLLARRSLQAQLQRLGVLHV
Sbjct: 361 EMQDELSYFLVDSAGQVVANQEGVFRSNCMDCLDRTNVIQSLLARRSLQAQLQRLGVLHV 420

Query: 421 GQKLEEQDEFEKIYKNAWADNANACAKQYAGTGALKTDFTRTGKRTHLGLIMDGWNSMIR 480
           GQKLEEQDEFEKIYKNAWADNANACAKQYAGTGALKTDFTRTGKRTHLGLIMDGWNSMIR
Sbjct: 421 GQKLEEQDEFEKIYKNAWADNANACAKQYAGTGALKTDFTRTGKRTHLGLIMDGWNSMIR 480

Query: 481 YYKNNFSDGFRQDSIDLFLGNYSVDELESHSPLSVPRDWKFLALPIIMVVAFSMCIICLL 540
           YYKNNFSDGFRQDSIDLFLGNYSVDELESHSPLSVPRDWKFLALPIIMVVAFSMCIICLL
Sbjct: 481 YYKNNFSDGFRQDSIDLFLGNYSVDELESHSPLSVPRDWKFLALPIIMVVAFSMCIICLL 540

Query: 541 MAGDTWTETLAYVLFWGVASIGTFFIILYNGKDFVDAPRLVQKEKID 587
           MAGDTWTETLAYVLFWGVASIGTFFIILYNGKDFVDAPRLVQKEKID
Sbjct: 541 MAGDTWTETLAYVLFWGVASIGTFFIILYNGKDFVDAPRLVQKEKID 587


>gi|7662414 inositol polyphosphate-5-phosphatase F [Homo sapiens]
          Length = 1132

 Score =  296 bits (759), Expect = 3e-80
 Identities = 166/437 (37%), Positives = 255/437 (58%), Gaps = 34/437 (7%)

Query: 101 KKTMLHLTDIQLQDNKTFLAMLNHVLNVDGFYFSTTYDLTHTLQRLSNTSPEFQEMSLLE 160
           KK +    + +  + +    +L   ++ + FY+S TYDLT+++QR S  + E     L +
Sbjct: 146 KKKVKESKEKEKLERRLLEELLKMFMDSESFYYSLTYDLTNSVQRQS--TGERDGRPLWQ 203

Query: 161 RADQRFVWNGHLLRELS--AQPEVHRFALPVLHGFITMHSCSIN---------------- 202
           + D RF WN +++++L+    P+V  + +P++ GF+ +    +N                
Sbjct: 204 KVDDRFFWNKYMIQDLTEIGTPDVDFWIIPMIQGFVQIEELVVNYTESSDDEKSSPETPP 263

Query: 203 ---------GKYFDWILISRRSCFRAGVRYYVRGIDSEGHAANFVETEQIVHYNGSKASF 253
                       F   LISRRS  RAG+RY  RG+D  G+ AN+VETEQ++H +    SF
Sbjct: 264 QESTCVDDIHPRFLVALISRRSRHRAGMRYKRRGVDKNGNVANYVETEQLIHVHNHTLSF 323

Query: 254 VQTRGSIPVFWSQRPNLKYKPLPQISKVANH-MDGFQRHFDSQVIIYGKQVIINLINQKG 312
           VQTRGS+PVFWSQ    +Y P P++ +     +  F  HF+ Q+ IY KQVIINL++Q G
Sbjct: 324 VQTRGSVPVFWSQ-VGYRYNPRPRLDRSEKETVAYFCAHFEEQLNIYKKQVIINLVDQAG 382

Query: 313 SEKPLEQTFATMVSSLGSGMMRYIAFDFHKECKNMRWDRLSILLDQVAEMQDELSYFLVD 372
            EK +   +   V    +  + Y++FDFH+ C+ M+++ +  L D + ++  ++ +  VD
Sbjct: 383 REKIIGDAYLKQVLLFNNSHLTYVSFDFHEHCRGMKFENVQTLTDAIYDIILDMKWCWVD 442

Query: 373 SAGQVVANQEGVFRSNCMDCLDRTNVIQSLLARRSLQAQLQRLGVLHVGQKLEEQDEFEK 432
            AG V+  QEG+FR NCMDCLDRTNV+Q+ +AR  ++ QL++LGV+   Q L    +  +
Sbjct: 443 EAG-VICKQEGIFRVNCMDCLDRTNVVQAAIARVVMEQQLKKLGVMPPEQPLPV--KCNR 499

Query: 433 IYKNAWADNANACAKQYAGTGALKTDFTRTGKRTHLGLIMDGWNSMIRYYKNNFSDGFRQ 492
           IY+  WA+N ++ ++QYAGT ALK DFTRTG+R   G++ DG NS  RYY N F D +RQ
Sbjct: 500 IYQIMWANNGDSISRQYAGTAALKGDFTRTGERKLAGVMKDGVNSANRYYLNRFKDAYRQ 559

Query: 493 DSIDLFLGNYSVDELES 509
             IDL  G    ++L S
Sbjct: 560 AVIDLMQGIPVTEDLYS 576


>gi|237757326 synaptojanin 1 isoform d [Homo sapiens]
          Length = 1526

 Score =  206 bits (524), Expect = 5e-53
 Identities = 146/454 (32%), Positives = 237/454 (52%), Gaps = 37/454 (8%)

Query: 58  FGILGTIHLVAGN----YLIVITKKIKVGEFFSHVVWKATDFDVLSYKKTMLHLTDIQLQ 113
           +G+LG + L  G+    YL+++T  + VG+     V++ T  + +S +       D   +
Sbjct: 60  YGLLGVLRLNLGDTMLHYLVLVTGCMSVGKIQESEVFRVTSTEFISLR------IDSSDE 113

Query: 114 DNKTFLAMLNHVLNVDGFYFSTTYDLTHTLQRLSNTSPEFQEMSLLERADQRFVWNGHLL 173
           D    ++ +  VLN   FYF+ +     +L    N     QE +     D RF WN  L 
Sbjct: 114 DR---ISEVRKVLNSGNFYFAWSASGI-SLDLSLNAHRSMQEQT----TDNRFFWNQSLH 165

Query: 174 RELSAQP-EVHRFALPVLHGFITMHSCSINGKYFDWILISRRSCFRAGVRYYVRGIDSEG 232
             L         + L ++ G + + +     K     LISR SC RAG R+ VRG + +G
Sbjct: 166 LHLKHYGVNCDDWLLRLMCGGVEIRTIYAAHKQAKACLISRLSCERAGTRFNVRGTNDDG 225

Query: 233 HAANFVETEQIVHYNGSKASFVQTRGSIPVFWSQRPNLKY--KPLPQISKVANHMDGFQR 290
           H ANFVETEQ+V+ + S +SF+Q RGS+P+FW Q P L+     +        +   F R
Sbjct: 226 HVANFVETEQVVYLDDSVSSFIQIRGSVPLFWEQ-PGLQVGSHRVRMSRGFEANAPAFDR 284

Query: 291 HFDSQVIIYGKQVIINLINQKGSEKPLEQTFAT-MVSSLGSGMMRYIAFDFHKECKNMRW 349
           HF +   +YGKQ+I+NL+  K  E  L + F + + +S  +  ++ + FD+H+  K  + 
Sbjct: 285 HFRTLKNLYGKQIIVNLLGSKEGEHMLSKAFQSHLKASEHAADIQMVNFDYHQMVKGGKA 344

Query: 350 DRL-SILLDQVAEMQDELSYFLVDSAGQVVANQEGVFRSNCMDCLDRTNVIQSLLARRSL 408
           ++L S+L  QV +  D   ++   +  +V   Q G  R+NC+DCLDRTN +Q+ L    L
Sbjct: 345 EKLHSVLKPQVQKFLDYGFFYF--NGSEVQRCQSGTVRTNCLDCLDRTNSVQAFLGLEML 402

Query: 409 QAQLQRLGVLHVGQKLEEQDEFEKIYKNAWADNANACAKQYAGTGALKTDFTRTGKRTHL 468
             QL+ LG   + +K +    F++++++ W+ N ++ +K YAGTGAL+        +   
Sbjct: 403 AKQLEALG---LAEKPQLVTRFQEVFRSMWSVNGDSISKIYAGTGALE-------GKAKA 452

Query: 469 GLIMDGWNSMIRYYKNNFSDGFRQDSID-LFLGN 501
           G + DG  S+ R  +NNF D  +Q++ID L LGN
Sbjct: 453 GKLKDGARSVTRTIQNNFFDSSKQEAIDVLLLGN 486


>gi|237757312 synaptojanin 1 isoform c [Homo sapiens]
          Length = 1295

 Score =  203 bits (517), Expect = 3e-52
 Identities = 147/454 (32%), Positives = 237/454 (52%), Gaps = 40/454 (8%)

Query: 58  FGILGTIHLVAGN----YLIVITKKIKVGEFFSHVVWKATDFDVLSYKKTMLHLTDIQLQ 113
           +G+LG + L  G+    YL+++T  + VG+     V++ T  + +S +       D   +
Sbjct: 60  YGLLGVLRLNLGDTMLHYLVLVTGCMSVGKIQESEVFRVTSTEFISLR------IDSSDE 113

Query: 114 DNKTFLAMLNHVLNVDGFYFSTTYDLTHTLQRLSNTSPEFQEMSLLERADQRFVWNGHLL 173
           D    ++ +  VLN   FYF+ +     +L    N     QE +     D RF WN  L 
Sbjct: 114 DR---ISEVRKVLNSGNFYFAWSASGI-SLDLSLNAHRSMQEQT----TDNRFFWNQSLH 165

Query: 174 RELSAQP-EVHRFALPVLHGFITMHSCSINGKYFDWILISRRSCFRAGVRYYVRGIDSEG 232
             L         + L ++ G + + +     K     LISR SC RAG R+ VRG + +G
Sbjct: 166 LHLKHYGVNCDDWLLRLMCGGVEIRTIYAAHKQAKACLISRLSCERAGTRFNVRGTNDDG 225

Query: 233 HAANFVETEQIVHYNGSKASFVQTRGSIPVFWSQRPNLKY--KPLPQISKVANHMDGFQR 290
           H ANFVETEQ+V+ + S +SF+Q RGS+P+FW Q P L+     +        +   F R
Sbjct: 226 HVANFVETEQVVYLDDSVSSFIQIRGSVPLFWEQ-PGLQVGSHRVRMSRGFEANAPAFDR 284

Query: 291 HFDSQVIIYGKQVIINLINQKGSEKPLEQTFAT-MVSSLGSGMMRYIAFDFHKECKNMRW 349
           HF +   +YGKQ+I+NL+  K  E  L + F + + +S  +  ++ + FD+H+  K  + 
Sbjct: 285 HFRTLKNLYGKQIIVNLLGSKEGEHMLSKAFQSHLKASEHAADIQMVNFDYHQMVKGGKA 344

Query: 350 DRL-SILLDQVAEMQDELSYFLVDSAGQVVANQEGVFRSNCMDCLDRTNVIQSLLARRSL 408
           ++L S+L  QV +  D   ++   +  +V   Q G  R+NC+DCLDRTN +Q+ L    L
Sbjct: 345 EKLHSVLKPQVQKFLDYGFFYF--NGSEVQRCQSGTVRTNCLDCLDRTNSVQAFLGLEML 402

Query: 409 QAQLQRLGVLHVGQKLEEQDEFEKIYKNAWADNANACAKQYAGTGALKTDFTRTGKRTHL 468
             QL+ LG   + +K +    F++++++ W+ N ++ +K YAGTGAL+      GK    
Sbjct: 403 AKQLEALG---LAEKPQLVTRFQEVFRSMWSVNGDSISKIYAGTGALE------GK---- 449

Query: 469 GLIMDGWNSMIRYYKNNFSDGFRQDSID-LFLGN 501
             + DG  S+ R  +NNF D  +Q++ID L LGN
Sbjct: 450 AKLKDGARSVTRTIQNNFFDSSKQEAIDVLLLGN 483


>gi|237757310 synaptojanin 1 isoform a [Homo sapiens]
          Length = 1612

 Score =  203 bits (517), Expect = 3e-52
 Identities = 147/454 (32%), Positives = 237/454 (52%), Gaps = 40/454 (8%)

Query: 58  FGILGTIHLVAGN----YLIVITKKIKVGEFFSHVVWKATDFDVLSYKKTMLHLTDIQLQ 113
           +G+LG + L  G+    YL+++T  + VG+     V++ T  + +S +       D   +
Sbjct: 99  YGLLGVLRLNLGDTMLHYLVLVTGCMSVGKIQESEVFRVTSTEFISLR------IDSSDE 152

Query: 114 DNKTFLAMLNHVLNVDGFYFSTTYDLTHTLQRLSNTSPEFQEMSLLERADQRFVWNGHLL 173
           D    ++ +  VLN   FYF+ +     +L    N     QE +     D RF WN  L 
Sbjct: 153 DR---ISEVRKVLNSGNFYFAWSASGI-SLDLSLNAHRSMQEQT----TDNRFFWNQSLH 204

Query: 174 RELSAQP-EVHRFALPVLHGFITMHSCSINGKYFDWILISRRSCFRAGVRYYVRGIDSEG 232
             L         + L ++ G + + +     K     LISR SC RAG R+ VRG + +G
Sbjct: 205 LHLKHYGVNCDDWLLRLMCGGVEIRTIYAAHKQAKACLISRLSCERAGTRFNVRGTNDDG 264

Query: 233 HAANFVETEQIVHYNGSKASFVQTRGSIPVFWSQRPNLKY--KPLPQISKVANHMDGFQR 290
           H ANFVETEQ+V+ + S +SF+Q RGS+P+FW Q P L+     +        +   F R
Sbjct: 265 HVANFVETEQVVYLDDSVSSFIQIRGSVPLFWEQ-PGLQVGSHRVRMSRGFEANAPAFDR 323

Query: 291 HFDSQVIIYGKQVIINLINQKGSEKPLEQTFAT-MVSSLGSGMMRYIAFDFHKECKNMRW 349
           HF +   +YGKQ+I+NL+  K  E  L + F + + +S  +  ++ + FD+H+  K  + 
Sbjct: 324 HFRTLKNLYGKQIIVNLLGSKEGEHMLSKAFQSHLKASEHAADIQMVNFDYHQMVKGGKA 383

Query: 350 DRL-SILLDQVAEMQDELSYFLVDSAGQVVANQEGVFRSNCMDCLDRTNVIQSLLARRSL 408
           ++L S+L  QV +  D   ++   +  +V   Q G  R+NC+DCLDRTN +Q+ L    L
Sbjct: 384 EKLHSVLKPQVQKFLDYGFFYF--NGSEVQRCQSGTVRTNCLDCLDRTNSVQAFLGLEML 441

Query: 409 QAQLQRLGVLHVGQKLEEQDEFEKIYKNAWADNANACAKQYAGTGALKTDFTRTGKRTHL 468
             QL+ LG   + +K +    F++++++ W+ N ++ +K YAGTGAL+      GK    
Sbjct: 442 AKQLEALG---LAEKPQLVTRFQEVFRSMWSVNGDSISKIYAGTGALE------GK---- 488

Query: 469 GLIMDGWNSMIRYYKNNFSDGFRQDSID-LFLGN 501
             + DG  S+ R  +NNF D  +Q++ID L LGN
Sbjct: 489 AKLKDGARSVTRTIQNNFFDSSKQEAIDVLLLGN 522


>gi|237757308 synaptojanin 1 isoform b [Homo sapiens]
          Length = 1350

 Score =  203 bits (517), Expect = 3e-52
 Identities = 147/454 (32%), Positives = 237/454 (52%), Gaps = 40/454 (8%)

Query: 58  FGILGTIHLVAGN----YLIVITKKIKVGEFFSHVVWKATDFDVLSYKKTMLHLTDIQLQ 113
           +G+LG + L  G+    YL+++T  + VG+     V++ T  + +S +       D   +
Sbjct: 99  YGLLGVLRLNLGDTMLHYLVLVTGCMSVGKIQESEVFRVTSTEFISLR------IDSSDE 152

Query: 114 DNKTFLAMLNHVLNVDGFYFSTTYDLTHTLQRLSNTSPEFQEMSLLERADQRFVWNGHLL 173
           D    ++ +  VLN   FYF+ +     +L    N     QE +     D RF WN  L 
Sbjct: 153 DR---ISEVRKVLNSGNFYFAWSASGI-SLDLSLNAHRSMQEQT----TDNRFFWNQSLH 204

Query: 174 RELSAQP-EVHRFALPVLHGFITMHSCSINGKYFDWILISRRSCFRAGVRYYVRGIDSEG 232
             L         + L ++ G + + +     K     LISR SC RAG R+ VRG + +G
Sbjct: 205 LHLKHYGVNCDDWLLRLMCGGVEIRTIYAAHKQAKACLISRLSCERAGTRFNVRGTNDDG 264

Query: 233 HAANFVETEQIVHYNGSKASFVQTRGSIPVFWSQRPNLKY--KPLPQISKVANHMDGFQR 290
           H ANFVETEQ+V+ + S +SF+Q RGS+P+FW Q P L+     +        +   F R
Sbjct: 265 HVANFVETEQVVYLDDSVSSFIQIRGSVPLFWEQ-PGLQVGSHRVRMSRGFEANAPAFDR 323

Query: 291 HFDSQVIIYGKQVIINLINQKGSEKPLEQTFAT-MVSSLGSGMMRYIAFDFHKECKNMRW 349
           HF +   +YGKQ+I+NL+  K  E  L + F + + +S  +  ++ + FD+H+  K  + 
Sbjct: 324 HFRTLKNLYGKQIIVNLLGSKEGEHMLSKAFQSHLKASEHAADIQMVNFDYHQMVKGGKA 383

Query: 350 DRL-SILLDQVAEMQDELSYFLVDSAGQVVANQEGVFRSNCMDCLDRTNVIQSLLARRSL 408
           ++L S+L  QV +  D   ++   +  +V   Q G  R+NC+DCLDRTN +Q+ L    L
Sbjct: 384 EKLHSVLKPQVQKFLDYGFFYF--NGSEVQRCQSGTVRTNCLDCLDRTNSVQAFLGLEML 441

Query: 409 QAQLQRLGVLHVGQKLEEQDEFEKIYKNAWADNANACAKQYAGTGALKTDFTRTGKRTHL 468
             QL+ LG   + +K +    F++++++ W+ N ++ +K YAGTGAL+      GK    
Sbjct: 442 AKQLEALG---LAEKPQLVTRFQEVFRSMWSVNGDSISKIYAGTGALE------GK---- 488

Query: 469 GLIMDGWNSMIRYYKNNFSDGFRQDSID-LFLGN 501
             + DG  S+ R  +NNF D  +Q++ID L LGN
Sbjct: 489 AKLKDGARSVTRTIQNNFFDSSKQEAIDVLLLGN 522


>gi|26190608 synaptojanin 2 [Homo sapiens]
          Length = 1496

 Score =  190 bits (482), Expect = 4e-48
 Identities = 147/492 (29%), Positives = 244/492 (49%), Gaps = 51/492 (10%)

Query: 26  GADDVLTIDRVSTEVTLAVKKDVPPSAVTR--PIFGILGTIHLVAG----NYLIVITKKI 79
           G DD L  +  +       +K+V      +    +G LG + L +G    ++L+++T   
Sbjct: 27  GRDDCLLFEAGTVATLAPEEKEVIKGQYGKLTDAYGCLGELRLKSGGTSLSFLVLVTGCT 86

Query: 80  KVGEFFSHVVWKATDFDVLSYKKTMLHLTDIQLQDNKTFLAMLNHVLNVDGFYFS----- 134
            VG      ++K T  D    ++        + ++ +  +A L  +L+   FYFS     
Sbjct: 87  SVGRIPDAEIYKITATDFYPLQE--------EAKEEERLIA-LKKILSSGVFYFSWPNDG 137

Query: 135 TTYDLTHTLQRLSNTSPEFQEMSLLERADQRFVWNGHLLRELSAQPEVH--RFALPVLHG 192
           + +DLT   Q+  + S E+            F WN  LL     Q +V    + L ++ G
Sbjct: 138 SRFDLTVRTQKQGDDSSEW---------GNSFFWN-QLLHVPLRQHQVSCCDWLLKIICG 187

Query: 193 FITMHSCSINGKYFDWILISRRSCFRAGVRYYVRGIDSEGHAANFVETEQIVHYNGSKAS 252
            +T+ +   + K     L+SR SC R G R++ RG++ +GH +NFVETEQ+++ +   +S
Sbjct: 188 VVTIRTVYASHKQAKACLVSRVSCERTGTRFHTRGVNDDGHVSNFVETEQMIYMDDGVSS 247

Query: 253 FVQTRGSIPVFWSQRPNLKY--KPLPQISKVANHMDGFQRHFDSQVIIYGKQVIINLINQ 310
           FVQ RGS+P+FW Q P L+     L     +  +   F RH       YG+QV++NL+  
Sbjct: 248 FVQIRGSVPLFWEQ-PGLQVGSHHLRLHRGLEANAPAFDRHMVLLKEQYGQQVVVNLLGS 306

Query: 311 KGSEKPLEQTFATMV-SSLGSGMMRYIAFDFHKECKNMRWDRLSILLDQVAEMQDELSYF 369
           +G E+ L + F  ++ +S  +G    I FDFH+  K  + ++L  LL    ++  E   F
Sbjct: 307 RGGEEVLNRAFKKLLWASCHAGDTPMINFDFHQFAKGGKLEKLETLLRPQLKLHWE--DF 364

Query: 370 LVDSAGQVVAN--QEGVFRSNCMDCLDRTNVIQSLLARRSLQAQLQRLGVLHVGQKLEEQ 427
            V + G+ V+   Q+G  R NC+DCLDRTN +QS +A   L  QL+ LG+          
Sbjct: 365 DVFTKGENVSPRFQKGTLRMNCLDCLDRTNTVQSFIALEVLHLQLKTLGL----SSKPIV 420

Query: 428 DEFEKIYKNAWADNANACAKQYAGTGALKTDFTRTGKRTHLGLIMDGWNSMIRYYKNNFS 487
           D F + +K  W+ N ++ +K + G+ AL+        +  +G + DG  SM R  ++NF 
Sbjct: 421 DRFVESFKAMWSLNGHSLSKVFTGSRALE-------GKAKVGKLKDGARSMSRTIQSNFF 473

Query: 488 DGFRQDSIDLFL 499
           DG +Q++I L L
Sbjct: 474 DGVKQEAIKLLL 485


>gi|7662034 Sac domain-containing inositol phosphatase 3 [Homo
           sapiens]
          Length = 907

 Score =  175 bits (444), Expect = 9e-44
 Identities = 149/523 (28%), Positives = 245/523 (46%), Gaps = 79/523 (15%)

Query: 58  FGILGTIHLVAGNYLIVITKKIKVGEFFSHVVWKATDFDVLSYKKTMLHLTDIQLQDNKT 117
           FG++G +  + G Y+++ITK+ K+ +   H ++K  D +++      + +T     D   
Sbjct: 93  FGVVGFVRFLEGYYIVLITKRRKMADIGGHAIYKVEDTNMIYIPNDSVRVTH---PDEAR 149

Query: 118 FLAMLNHVLNVDGFYFSTTYDLTHTLQ---------------RLSNTSPE----FQEMSL 158
           +L +  +V     FYFS +YDL+H+LQ                ++    E    F++  L
Sbjct: 150 YLRIFQNVDLSSNFYFSYSYDLSHSLQYNLTVLRMPLEMLKSEMTQNRQESFDIFEDEGL 209

Query: 159 LERADQ-----------RFVWNGHLLRELSAQPEVHR-FALPVLHGFITMHSCSINGKYF 206
           + +              ++VWNG LL  + +   VHR + L ++HGF       I G+  
Sbjct: 210 ITQGGSGVFGICSEPYMKYVWNGELLDIIKST--VHRDWLLYIIHGFCGQSKLLIYGRPV 267

Query: 207 DWILISRRSCFRAGVRYYVRGIDSEGHAANFVETEQIV-------HYNGSKASFVQTRGS 259
              LI+RRS   AG R+  RG + EG  AN VETEQI+          GS +S+VQ RGS
Sbjct: 268 YVTLIARRSSKFAGTRFLKRGANCEGDVANEVETEQILCDASVMSFTAGSYSSYVQVRGS 327

Query: 260 IPVFWSQRPNLKYKPLPQISKVANHMDGFQR----HFDSQVIIYGKQVII-NLINQKGS- 313
           +P++WSQ  +    P P I+   +  D F      HFD     +G  +II NL+ ++   
Sbjct: 328 VPLYWSQDIS-TMMPKPPIT--LDQADPFAHVAALHFDQMFQRFGSPIIILNLVKEREKR 384

Query: 314 --EKPLEQTFATMVSSLGSGM-----MRYIAFDFHKECKNMR---WDRLSILLDQVAE-- 361
             E+ L +     V+ L   +     + YI +D  K  K+      DRL+++ + V +  
Sbjct: 385 KHERILSEELVAAVTYLNQFLPPEHTIVYIPWDMAKYTKSKLCNVLDRLNVIAESVVKKT 444

Query: 362 ---MQDELSYFLV--------DSAGQVVAN---QEGVFRSNCMDCLDRTNVIQSLLARRS 407
              +    SY  +        +  G V+     Q G+ R+NC+DCLDRTN  Q ++ + +
Sbjct: 445 GFFVNRPDSYCSILRPDEKWNELGGCVIPTGRLQTGILRTNCVDCLDRTNTAQFMVGKCA 504

Query: 408 LQAQLQRLGVLHVGQKLEEQDEFEKIYKNAWADNANACAKQYAGTGALKTDFTRTGKRTH 467
           L  QL  LG++     L+   +  ++++  + D+ +  + QY G+  +    T       
Sbjct: 505 LAYQLYSLGLID-KPNLQFDTDAVRLFEELYEDHGDTLSLQYGGSQLVHRVKTYRKIAPW 563

Query: 468 LGLIMDGWNSMIRYYKNNFSDGFRQDSIDLFLGNYSVDELESH 510
                D   ++ RYY N FSD  RQDSI+LFLG +   E + H
Sbjct: 564 TQHSKDIMQTLSRYYSNAFSDADRQDSINLFLGVFHPTEGKPH 606


>gi|148664197 coiled-coil domain containing 40 [Homo sapiens]
          Length = 1142

 Score = 30.8 bits (68), Expect = 3.6
 Identities = 15/49 (30%), Positives = 25/49 (51%)

Query: 98  LSYKKTMLHLTDIQLQDNKTFLAMLNHVLNVDGFYFSTTYDLTHTLQRL 146
           ++  KT  +   + L+  K    M+ H+  ++G    TT D+THT  RL
Sbjct: 640 MTSNKTTKYFNQLILRLQKEKTNMMTHLSKINGDIAQTTLDITHTSSRL 688


>gi|4507491 thimet oligopeptidase 1 [Homo sapiens]
          Length = 689

 Score = 30.4 bits (67), Expect = 4.7
 Identities = 25/95 (26%), Positives = 42/95 (44%), Gaps = 11/95 (11%)

Query: 94  DFDVLSYKKTMLHLTDIQLQDN--KTFLAMLNHVLNVDGFYFSTTYDLTHTLQRLSNTSP 151
           +F+ +SY+ T+  L D+++     +  L    HV        S + D+            
Sbjct: 55  EFEDVSYESTLKALADVEVTYTVQRNILDFPQHV--------SPSKDIRTASTEADKKLS 106

Query: 152 EFQ-EMSLLERADQRFVWNGHLLRELSAQPEVHRF 185
           EF  EMS+ E   QR VW    +++ S +PE  R+
Sbjct: 107 EFDVEMSMREDVYQRIVWLQEKVQKDSLRPEAARY 141


>gi|4502827 cholinergic receptor, nicotinic, alpha 4 subunit
           precursor [Homo sapiens]
          Length = 627

 Score = 30.0 bits (66), Expect = 6.2
 Identities = 14/40 (35%), Positives = 23/40 (57%), Gaps = 1/40 (2%)

Query: 502 YSVDELESH-SPLSVPRDWKFLALPIIMVVAFSMCIICLL 540
           Y  D L++  +  SV  DWK++A+ I  +  +   I+CLL
Sbjct: 573 YIADHLKAEDTDFSVKEDWKYVAMVIDRIFLWMFIIVCLL 612


>gi|21735548 centrosomal protein 2 [Homo sapiens]
          Length = 2442

 Score = 29.6 bits (65), Expect = 8.1
 Identities = 26/90 (28%), Positives = 38/90 (42%), Gaps = 1/90 (1%)

Query: 354  ILLDQVAEMQDELSYFLVDSAGQVVANQEGVFRSNCMDCLDRTNVIQSLLARRSLQAQLQ 413
            IL  Q+ E Q EL          + A QE    S   D +D    ++ L ++   Q   Q
Sbjct: 968  ILQTQLQEAQRELKEAARQHRDDLAALQEES-SSLLQDKMDLQKQVEDLKSQLVAQDDSQ 1026

Query: 414  RLGVLHVGQKLEEQDEFEKIYKNAWADNAN 443
            RL    V +KL E  E+ +I K    + A+
Sbjct: 1027 RLVEQEVQEKLRETQEYNRIQKELEREKAS 1056


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.137    0.416 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,751,240
Number of Sequences: 37866
Number of extensions: 866201
Number of successful extensions: 2255
Number of sequences better than 10.0: 12
Number of HSP's better than 10.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 2206
Number of HSP's gapped (non-prelim): 17
length of query: 587
length of database: 18,247,518
effective HSP length: 108
effective length of query: 479
effective length of database: 14,157,990
effective search space: 6781677210
effective search space used: 6781677210
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.5 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.