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Search of human proteins with 187936946
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|187936946 hypothetical protein LOC84140 [Homo sapiens]
(660 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|187936946 hypothetical protein LOC84140 [Homo sapiens] 1325 0.0
gi|22748943 hypothetical protein LOC145483 [Homo sapiens] 178 1e-44
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 55 2e-07
gi|148746195 trichohyalin [Homo sapiens] 55 2e-07
gi|154759273 testis specific, 10 interacting protein [Homo sapiens] 55 2e-07
gi|125656165 THO complex 2 [Homo sapiens] 52 2e-06
gi|46049114 M-phase phosphoprotein 1 [Homo sapiens] 51 3e-06
gi|7657671 upstream binding transcription factor, RNA polymerase... 49 1e-05
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 49 2e-05
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 47 7e-05
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 46 1e-04
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 46 1e-04
gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens] 46 1e-04
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 46 1e-04
gi|115529449 upstream binding transcription factor, RNA polymera... 46 1e-04
gi|115529451 upstream binding transcription factor, RNA polymera... 46 1e-04
gi|88759339 aster-associated protein [Homo sapiens] 45 2e-04
gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens] 45 2e-04
gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isof... 45 2e-04
gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isof... 45 2e-04
gi|29294649 dicer1 [Homo sapiens] 45 3e-04
gi|29294651 dicer1 [Homo sapiens] 45 3e-04
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 45 3e-04
gi|100816397 MYST histone acetyltransferase (monocytic leukemia)... 44 4e-04
gi|146260271 hypothetical protein LOC129881 [Homo sapiens] 44 4e-04
gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo sap... 44 5e-04
gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens] 44 5e-04
gi|221219020 NYD-SP11 protein [Homo sapiens] 44 6e-04
gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof... 44 6e-04
gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isof... 44 6e-04
>gi|187936946 hypothetical protein LOC84140 [Homo sapiens]
Length = 660
Score = 1325 bits (3429), Expect = 0.0
Identities = 660/660 (100%), Positives = 660/660 (100%)
Query: 1 MATSHRVAKLVASSLQTPVNPITGARVAQYEREDPLKALAAAEAILEDEEEEKVAQPAGA 60
MATSHRVAKLVASSLQTPVNPITGARVAQYEREDPLKALAAAEAILEDEEEEKVAQPAGA
Sbjct: 1 MATSHRVAKLVASSLQTPVNPITGARVAQYEREDPLKALAAAEAILEDEEEEKVAQPAGA 60
Query: 61 SADLNTSFSGVDEHAPISYEDFVNFPDIHHSNEEYFKKVEELKAAHIETMAKLEKMYQDK 120
SADLNTSFSGVDEHAPISYEDFVNFPDIHHSNEEYFKKVEELKAAHIETMAKLEKMYQDK
Sbjct: 61 SADLNTSFSGVDEHAPISYEDFVNFPDIHHSNEEYFKKVEELKAAHIETMAKLEKMYQDK 120
Query: 121 LHLKEVQPVVIREDSLSDSSRSVSEKNSYHPVSLMTSFSEPDLGQSSSLYVSSSEEELPN 180
LHLKEVQPVVIREDSLSDSSRSVSEKNSYHPVSLMTSFSEPDLGQSSSLYVSSSEEELPN
Sbjct: 121 LHLKEVQPVVIREDSLSDSSRSVSEKNSYHPVSLMTSFSEPDLGQSSSLYVSSSEEELPN 180
Query: 181 LEKEYPRKNRMMTYAKELINNMWTDFCVEDYIRCKDTGFHAAEKRRKKRKEWVPTITVPE 240
LEKEYPRKNRMMTYAKELINNMWTDFCVEDYIRCKDTGFHAAEKRRKKRKEWVPTITVPE
Sbjct: 181 LEKEYPRKNRMMTYAKELINNMWTDFCVEDYIRCKDTGFHAAEKRRKKRKEWVPTITVPE 240
Query: 241 PFQMMIREQKKKEESMKSKSDIEMVHKALKKQEEDPEYKKKFRANPVPASVFLPLYHDLV 300
PFQMMIREQKKKEESMKSKSDIEMVHKALKKQEEDPEYKKKFRANPVPASVFLPLYHDLV
Sbjct: 241 PFQMMIREQKKKEESMKSKSDIEMVHKALKKQEEDPEYKKKFRANPVPASVFLPLYHDLV 300
Query: 301 KQKEERRRSLKEKSKEALLASQKPFKFIAREEQKRAAREKQLRDFLKYKKKTNRFKARPI 360
KQKEERRRSLKEKSKEALLASQKPFKFIAREEQKRAAREKQLRDFLKYKKKTNRFKARPI
Sbjct: 301 KQKEERRRSLKEKSKEALLASQKPFKFIAREEQKRAAREKQLRDFLKYKKKTNRFKARPI 360
Query: 361 PRSTYGSTTNDKLKEEELYRNLRTQLRAQEHLQNSSPLPCRSACGCRNPRCPEQAVKLKC 420
PRSTYGSTTNDKLKEEELYRNLRTQLRAQEHLQNSSPLPCRSACGCRNPRCPEQAVKLKC
Sbjct: 361 PRSTYGSTTNDKLKEEELYRNLRTQLRAQEHLQNSSPLPCRSACGCRNPRCPEQAVKLKC 420
Query: 421 KHKVRCPTPDFEDLPERYQKHLSEHKSPKLLTVCKPFDLHASPHASIKREKILADIEADE 480
KHKVRCPTPDFEDLPERYQKHLSEHKSPKLLTVCKPFDLHASPHASIKREKILADIEADE
Sbjct: 421 KHKVRCPTPDFEDLPERYQKHLSEHKSPKLLTVCKPFDLHASPHASIKREKILADIEADE 480
Query: 481 ENLKETRWPYLSPRRKSPVRCAGVNPVPCNCNPPVPTVSSRGREQAVRKSEKERMREYQR 540
ENLKETRWPYLSPRRKSPVRCAGVNPVPCNCNPPVPTVSSRGREQAVRKSEKERMREYQR
Sbjct: 481 ENLKETRWPYLSPRRKSPVRCAGVNPVPCNCNPPVPTVSSRGREQAVRKSEKERMREYQR 540
Query: 541 ELEEREEKLKKRPLLFERVAQKNARMAAEKHYSNTLKALGISDEFVSKKGQSGKVLEYFN 600
ELEEREEKLKKRPLLFERVAQKNARMAAEKHYSNTLKALGISDEFVSKKGQSGKVLEYFN
Sbjct: 541 ELEEREEKLKKRPLLFERVAQKNARMAAEKHYSNTLKALGISDEFVSKKGQSGKVLEYFN 600
Query: 601 NQETKSVTEDKESFNEEEKIEERENGEENYFIDTNSQDSYKEKDEANEESEEEKSVEESH 660
NQETKSVTEDKESFNEEEKIEERENGEENYFIDTNSQDSYKEKDEANEESEEEKSVEESH
Sbjct: 601 NQETKSVTEDKESFNEEEKIEERENGEENYFIDTNSQDSYKEKDEANEESEEEKSVEESH 660
>gi|22748943 hypothetical protein LOC145483 [Homo sapiens]
Length = 647
Score = 178 bits (452), Expect = 1e-44
Identities = 140/462 (30%), Positives = 227/462 (49%), Gaps = 82/462 (17%)
Query: 232 WVPTITVPEPFQMMIREQKKKEESMKSKSDIEMVHKALKKQ-EEDPEYKKKFRANPVPAS 290
W +ITVP PF+M +RE +KK E + S + E + ++Q EE+ E ++FRA PVPA
Sbjct: 165 WASSITVPRPFRMTLREARKKAEWLGSPASFEQERQRAQRQGEEEAECHRQFRAQPVPAH 224
Query: 291 VFLPLYHDLVKQKEERRRSLKEKSKEALLASQKPFKFIAREEQ-KRAAREKQLRDFLKYK 349
V+LPLY +++++ E RR++ +K KE LL+S KPF F+ +EEQ K AAR++ L + K
Sbjct: 225 VYLPLYQEIMERSEARRQAGIQKRKELLLSSLKPFSFLEKEEQLKEAARQRDLAATAEAK 284
Query: 350 KKTNRFKARPIPRSTYGSTTNDKLKEEELYRNLRTQLRAQEHLQNSSPLPCRSACGCRNP 409
+ R IP+S DKL+E EL+R +R Q+RA + LQ +S P S+ NP
Sbjct: 285 ISKQK-ATRRIPKSILEPALGDKLQEAELFRKIRIQMRALDMLQMASS-PIASSSNRANP 342
Query: 410 RCPEQAVK------------LKCKHKVRCPTPDFEDLPERYQKHLSEHKSPKLLTVCKPF 457
+ P A + + + +V PD+E L + +Q+ ++ + + T KPF
Sbjct: 343 Q-PRTATRTQQEKLGFLHTNFRFQPRVNPVVPDYEGLYKAFQRRAAKRRETQEATRNKPF 401
Query: 458 DLHASPHASIKREKILADIEADEENLKETRWPYLSPRRKSPVRCAGVNPVPCNCNPPVPT 517
L + +R A +++ + P PR +S +G+ + N P T
Sbjct: 402 LLRTANLRHPQRPCDAATTGRRQDSPQPPATPL--PRSRS---LSGLASLSANTLPVHIT 456
Query: 518 VSSRGREQAVR---------------------KSE-----------------------KE 533
++R RE AVR KS+ K
Sbjct: 457 DATRKRESAVRSALEKKNKADESIQWLEIHRKKSQAMSKSVTLRAKAMDPHKSLEEVFKA 516
Query: 534 RMRE-----------YQRELEEREEKLKKRPLLFERVAQKNARMAAEKHYSNTLKALGIS 582
+++E Y++ELEE +++++ RP LFE+VA+ A+ AE+ Y +TLK G+
Sbjct: 517 KLKENRNNDRKRAKEYKKELEEMKQRIQTRPYLFEQVAKDLAKKEAEQWYLDTLKQAGLE 576
Query: 583 DEFVSKKGQSGKVLEYFNNQETKSVTEDKESFNEEEKIEERE 624
++FV KGQ + + QE ++ +D F E K+ R+
Sbjct: 577 EDFVRNKGQGTRAV-----QEKETKIKDFPRFQETTKLSIRD 613
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 55.5 bits (132), Expect = 2e-07
Identities = 104/599 (17%), Positives = 240/599 (40%), Gaps = 63/599 (10%)
Query: 88 IHHSNEEYFKKVEELKAAHIETMAKLEKMYQDKLHLKEVQPVVIREDSLSDSSRSVSEKN 147
I E+ +++ E L+ + + EKM++ + L+E + + ++ + + E+
Sbjct: 288 IRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQE 347
Query: 148 SYHPVSLMTSFSEPDLGQSSSLYVSSSEEELPNLEKEYPRKNRMMTYAKELINNMWTDFC 207
+ + + + + EE L EK+ + + M +E MW
Sbjct: 348 EQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEE---RMWEQ-- 402
Query: 208 VEDYIRCKDTGFHAAEKRRKKRKEWVPTITVPEPFQMMIREQKKK--EESMKSKSDIEMV 265
++ +R K+ E+ R++ K W + E +M +E+K + EE M+ + I
Sbjct: 403 -DERLREKE------ERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIRER 455
Query: 266 HKALKKQEED----------------PEYKKKFRANPVPASVFLPLYHDLVKQKEERRRS 309
K ++++EE + +K+++ +P + ++++EE+
Sbjct: 456 EKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWE 515
Query: 310 LKEK--SKEALLASQKPF----KFIAREEQKRAAREKQLRDFLKYKKKTNRFKARPIPRS 363
+EK +E + +K K +E+Q EK K + R + + +
Sbjct: 516 QEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQE 575
Query: 364 TYGSTTNDKLKEEELYRNLRTQLRAQEHLQNSSPLPCRSACGCRNPRCPEQAVKLKCKHK 423
+K++EEE R ++R +E + + + EQ K++ + +
Sbjct: 576 KKTWDQEEKMREEERMREREKKMREEEEMMRE-----------QEEKMQEQEEKMQEQEE 624
Query: 424 VRCPTPDFEDLPERYQKHLSEHKSPKLLTVCKPFDLHASPHASIKREKILADIEADEENL 483
+ E+ + ++ + E + K ++ P ++EK+ + E+
Sbjct: 625 KMW---EQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPE---QKEKLWEHEKMQEQEK 678
Query: 484 KETRWPYLSPRRKSPVRCAGVNPVPCNCNPPVPTVSSRGREQAVRKSEKERMREYQRELE 543
+ + + + K + + S R RE+ +R+ E+E MRE + +++
Sbjct: 679 MQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMRE-EEEMMREQEEKMQ 737
Query: 544 EREEKLKKRPLLF----ERVAQKNARMAAEKHYSNTLKALGISDEFVSKKGQSGKVLEYF 599
E+EEK++++ E++ ++ +M ++ + L E + ++ + + E
Sbjct: 738 EQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLW-EHEKMQEQEKIWEQEEKM 796
Query: 600 NNQETKSVTEDKESFNEEEKIEERE----NGEENYFIDTNSQDSYKEKDEANEESEEEK 654
+QE K ++++ +EEK+ +E EE + +EK EE EEK
Sbjct: 797 RDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEK 855
Score = 53.5 bits (127), Expect = 6e-07
Identities = 100/505 (19%), Positives = 207/505 (40%), Gaps = 76/505 (15%)
Query: 175 EEELPNLEKEYPRKNRMMTYAKELINN-----------MWTDFCVEDYIRCKDTGFHAAE 223
EEEL EK+ ++ M +E + MW E +R ++ E
Sbjct: 278 EEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQ---EKRLREQEKELREQE 334
Query: 224 KRRKKRKEWVPTITVPEPFQMMIREQKKKEESMKSKSDIEMVHKALKKQEEDPEYKKKFR 283
K +++KE + QM +E+K E+ K + E K +++E E +K+ R
Sbjct: 335 KELREQKE-----LREQEEQMQEQEEKMWEQEEKMR---EQEEKMWRQEERLWEQEKQMR 386
Query: 284 ANPVPASVFLPLYHDLVKQKEERRRSLKEKSKEALLASQKPFKFIAREEQKRAAREKQLR 343
+ + + +++ER R +E+ +E ++ K REE+K +EK+ R
Sbjct: 387 EQEQK----MRDQEERMWEQDERLREKEERMREQEKMWEQVEKM--REEKKMQEQEKKTR 440
Query: 344 DFLKYKKKTNRFKARPIPRSTYGSTTNDKLKEEELYRNLRTQLRAQEHLQNSSPLPCRSA 403
D + ++ R + R T ++ EE++ + +E LP +
Sbjct: 441 DQEEKMQEEERIREREKKMREEEETMREQ--EEKMQKQEENMWEQEEKEWQQQRLPEQKE 498
Query: 404 CGCRNPRCPEQAVKL-KCKHKVRCPTPDFEDLPERYQKHLSEHKSPKLLTVCKPFDLHAS 462
+ EQ K+ + + K+R D E++ + +K + K + + +
Sbjct: 499 KLWEQEKMQEQEEKIWEQEEKIR----DQEEMWGQEKKMWRQEKMRE-----QEDQMWEQ 549
Query: 463 PHASIKREKILAD----IEADEENLKETRWPYLSPRRKSPVRCAGVNPVPCNCNPPVPTV 518
+E+ + D +E + ++ W R+
Sbjct: 550 EEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEE-------------------- 589
Query: 519 SSRGREQAVRKSEKERMREYQRELEEREEKLKKRPLLFERVAQKNARMAA--EKHYSNTL 576
R RE+ +R+ E+E MRE + +++E+EEK++++ E++ ++ +M EK +
Sbjct: 590 RMREREKKMRE-EEEMMREQEEKMQEQEEKMQEQE---EKMWEQEEKMQEQEEKMWEQEE 645
Query: 577 KALGISDEFVSKKG---QSGKVLEYFNNQETKSVTEDKESFNEEEKIEERENGEENYFID 633
K ++ ++ Q K+ E+ QE + + E +E E+EK+E++ +E
Sbjct: 646 KMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEK---K 702
Query: 634 TNSQDSYKEKDEANEESEEEKSVEE 658
T Q+ +E++ E ++ + EE
Sbjct: 703 TWDQEKMREEESMREREKKMREEEE 727
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 55.1 bits (131), Expect = 2e-07
Identities = 87/436 (19%), Positives = 165/436 (37%), Gaps = 88/436 (20%)
Query: 247 REQKKKEESMKSKSDIEMVHKALKKQEEDPEYKKKFRANPVPASVFLPLYHDLVKQKEER 306
REQ+++ E + E + LK+QEE+ +++ R+ L +++EER
Sbjct: 497 REQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSE-----------QQLRREQEER 545
Query: 307 RRSLKEKSKEALLASQKPFKFIAREEQKR-----AAREKQLRDFLKYKKK---TNRFKAR 358
R L ++ +E L ++ + + RE+++R E++ + LK +++ R K
Sbjct: 546 REQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKRE 605
Query: 359 PIPRSTYGSTTNDKLKEEELYRNLRTQLRAQEHLQNSSPLPCRSACGCRNPRCPEQAVKL 418
+ R +LK EE R QL E + R R EQ +K
Sbjct: 606 EVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERR----EQRLKR 661
Query: 419 KCKHKVRCPTPDFEDLPERYQKHLSEHKSPKLLTVCKPFDLHASPHASIKREKILADIEA 478
+ + E L +R ++ E + + L + + I + + + EA
Sbjct: 662 E---------EEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEA 712
Query: 479 DEENLKETRWPYLSPRRKSPVRCAGVNPVPCNCNPPVPTVSSRGREQAVRKSEKERMREY 538
D K Y PR++ R R RE ++ E+ER
Sbjct: 713 DARQSK----VYSRPRKQEGQR-----------RRQEQEEKRRRRESELQWQEEERAHRQ 757
Query: 539 QRELEER----------------EEKLKKRPLLFERVAQKNARMAAEKHYSNTLKALGIS 582
Q+E E+R ++L RP L E Q+ ++ AE+ + L
Sbjct: 758 QQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLRE---QRERQLRAEERQQREQRFLPEE 814
Query: 583 DEFVSKKGQSGKVLEYFNNQETKSVTEDKESFNEEEKIEERENGEENYFIDTNSQDSYKE 642
+E ++ ++ + ++ + EEE+++ RE +Q +E
Sbjct: 815 EEKEQRR------------RQRREREKELQFLEEEEQLQRRE----------RAQQLQEE 852
Query: 643 KDEANEESEEEKSVEE 658
+D E+ E +S E+
Sbjct: 853 EDGLQEDQERRRSQEQ 868
Score = 46.6 bits (109), Expect = 7e-05
Identities = 80/453 (17%), Positives = 181/453 (39%), Gaps = 67/453 (14%)
Query: 223 EKRRKKRKEWVPTITVPEPFQMMIR--EQKKKEESMKSKSDIEMVHKALKKQEEDPEYKK 280
E ++R++ + + E Q +R +Q+++E+ +K + + E + + LK++ E+ ++
Sbjct: 624 EPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQ 683
Query: 281 KFRANPVPASVFLPLYHDLVKQKEERRRSLKEKSKEALL--ASQKPFKFIAREEQKRAAR 338
+ L + +Q ER +S K + L A + K +R ++ R
Sbjct: 684 E-------------LAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQR 730
Query: 339 EKQLRDFLKYKKKTNRFKARPIPRSTYGSTTNDKLKEEELYRNLRTQLRAQEHLQNSSPL 398
+Q ++ K +++ + + + R+ + + +EEE R+ Q +A+E +
Sbjct: 731 RRQEQEE-KRRRRESELQWQEEERA------HRQQQEEEQRRDFTWQWQAEEKSERG--- 780
Query: 399 PCRSACGCRNPRCPEQAVKLKCKHKVRCPT---PDFEDLPERYQKHLSEHKSPKLLTVCK 455
R R P ++ +L+ + + + P+ E+ +R ++ K + L +
Sbjct: 781 --RQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEE 838
Query: 456 PFDLHASPHASIKREKILADIEA---DEENLKETRWPY-LSPRRKSPVRCAGVNPVPCNC 511
+ E L + + +E ++ +W + L RK P
Sbjct: 839 QLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPA---- 894
Query: 512 NPPVPTVSSRGREQAVRKSEKERMR----------EYQRELEEREEKLKKRPLLFERVAQ 561
+EQ + + E+E ++ E +R+ E E+ ++ L +
Sbjct: 895 -----LQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREERE 949
Query: 562 KNARMAAEKHYSNTLKALGISDEFVSKKGQSGKVLEYFNNQETKSVTEDKESFNEEEKI- 620
K R E+ Y K ++ + ++ + + + K E++E EEE++
Sbjct: 950 KRRRQERERQYRKDKKLQQKEEQLLGEEPEKRR-----RQEREKKYREEEELQQEEEQLL 1004
Query: 621 -EERENGEENYFIDTNSQDSYKEKDEANEESEE 652
EERE + + Y++KDE +E E+
Sbjct: 1005 REEREKRRRQEW-----ERQYRKKDELQQEEEQ 1032
Score = 45.8 bits (107), Expect = 1e-04
Identities = 87/470 (18%), Positives = 181/470 (38%), Gaps = 66/470 (14%)
Query: 225 RRKKRKEWVPTITVPEPFQMMIRE-----QKKKEESMKSKSDIEMVHKALKKQEEDPEYK 279
+ ++ KEW TV + ++E Q++ +E + +E ++QEE+ + +
Sbjct: 239 QEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQ 298
Query: 280 KKFRANPVPASVFLPLYHDLVKQKEERRRSLKEKSKEALLASQKPFKFIAREEQKRAARE 339
+ R + KQ+EERR +E+ ++ Q+ + RE+Q R +E
Sbjct: 299 RLRREQQLRR-----------KQEEERREQQEERREQQERREQQEER---REQQLRREQE 344
Query: 340 KQLRDFLKYKKKTNRFKARPIPRSTYGSTTNDKLKEEELYRNLRTQLRAQEHLQNSSPLP 399
++ L+ +++ R + + + R +L+ E+ R QLR ++ L+ L
Sbjct: 345 ERREQQLRREQEEER-REQQLRREQEEERREQQLRREQQLRR-EQQLRREQQLRREQQL- 401
Query: 400 CRSACGCRNPRCPEQAVKLKCKHKVRCPTPDFEDLPERY-QKHLSEHKSPKLLTVCKPFD 458
R R + + +L+ + ++R E ER+ QKH E + +L +
Sbjct: 402 -RREQQLRREQQLRREQQLRREQQLRR-----EQEEERHEQKHEQERREQRLKREQEERR 455
Query: 459 LHASPHASIKR---EKILADIEADEENLKETRWPYLSP--------RRKSPVRCAGVN-- 505
+R E+ ++ D+E + RW L RR+ +R
Sbjct: 456 DWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERR 515
Query: 506 -------------PVPCNCNPPVPTVSSRGREQAVRKSEKERMREYQRELEEREEKLKKR 552
+ REQ +++ E++R+ + +RE + E+ ++R
Sbjct: 516 EQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERR 575
Query: 553 PLLFERVAQKNARMAAEKHYSNTLKALGISDEFVSKKGQSGKVLEYFNNQETKSVTEDKE 612
L +R ++ + + + L K + + LE +E + E+ E
Sbjct: 576 DQLLKREEERRQQRLKREQEERLEQRL---------KREEVERLEQEERREQRLKREEPE 626
Query: 613 SFNEEEKIEERENGEENYFIDTNSQDSYKEKDEANEESEE--EKSVEESH 660
++ ++ E E Q +E+ EE EE E+ ++ H
Sbjct: 627 EERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREH 676
Score = 42.4 bits (98), Expect = 0.001
Identities = 73/422 (17%), Positives = 176/422 (41%), Gaps = 28/422 (6%)
Query: 247 REQKKKEESMKSKSDIEMVHKALKKQEEDPEYKKKFRANPVPASVFLPLYHDLVKQKEER 306
+E++++E+ ++ + + E + L+++++ ++ R + L L +++++
Sbjct: 355 QEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQL-RREQQL 413
Query: 307 RRSLKEKSKEALLASQKPFKFIAREEQKRAAR-----EKQLRDFLKYKKKTNRF----KA 357
RR + + ++ L Q+ + + EQ+R + +++ RD+LK +++T R +
Sbjct: 414 RREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRK 473
Query: 358 RPIPRSTYGSTTNDKLKEEELYRNLRTQLRAQEHLQNSSPLPCRSACGCRNPRCPEQAVK 417
+ + R LK EE R + + R Q+ + R R Q +
Sbjct: 474 QQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEER--------REQRLKRQEEE 525
Query: 418 LKCKHKVRCPTPDFEDLPERYQKHLSEHKSPKLLTVCKPFDLHASPHASIKREKIL-ADI 476
+ + ++R + ER ++ L + +L + L +R+++L +
Sbjct: 526 ERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEE--RRDQLLKREE 583
Query: 477 EADEENLKETRWPYLSPR--RKSPVRCAGVNPVPCNCNPPVPTVSSRGREQAVRKSEKER 534
E ++ LK + L R R+ R P R + + E+ R
Sbjct: 584 ERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERR 643
Query: 535 MREYQRELEEREEKLKKRPLLFERVAQKNARMAAEKHYSNTLKALGISDEFVSKKGQSGK 594
++ +RE +ER E+ KR ER+ Q R+ E + L ++ +++ +
Sbjct: 644 QQQLRREQQERREQRLKREEEEERLEQ---RLKREHEEERREQELAEEEQEQARERIKSR 700
Query: 595 VLEYFNNQETKSVTEDKESFNEEEKIE--ERENGEENYFIDTNSQDSYKEKDEANEESEE 652
+ ++ E+++ + ++ K E R +E S+ ++E++ A+ + +E
Sbjct: 701 IPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQE 760
Query: 653 EK 654
E+
Sbjct: 761 EE 762
Score = 42.4 bits (98), Expect = 0.001
Identities = 90/494 (18%), Positives = 188/494 (38%), Gaps = 111/494 (22%)
Query: 222 AEKRRKKRKEWVPTITVPEPFQMMIREQKKKEESMKSKSDIEMVHKALKKQEEDP----- 276
AE+R+++ + ++P E + RE++K+ + ++ + ++ +A + QEE+
Sbjct: 800 AEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQED 859
Query: 277 -------------------EYKKKFRANPVPASVFLPLY----HDLVKQKEE-------- 305
E ++K R + + A L L++++EE
Sbjct: 860 QERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREERE 919
Query: 306 -RRRSLKE---KSKEALLASQKPFKFIAREEQKRAAREKQLRDFLKYKKKTNRF------ 355
RRR +E + +E L ++ RE+++R RE+Q R K ++K +
Sbjct: 920 KRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPE 979
Query: 356 -KARPIPRSTYGSTTNDKLKEEELYRNLRTQLRAQE---HLQNSSPLPCRSACGCRNPRC 411
+ R Y + +EE+L R R + R QE + L R R
Sbjct: 980 KRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREERE 1039
Query: 412 PEQAVKLKCKHKVRCPTPDFEDLPERYQKHLSEHKSPKLLTVCKPFDLHASPHASIKREK 471
+ + + +++ + E+L + ++ L E + + ++E+
Sbjct: 1040 KRRLQERERQYR------EEEELQQEEEQLLGEERETR---------RRQELERQYRKEE 1084
Query: 472 ILADIEADEENLKETRWPYLSPRRKSPVRCAGVNPVPCNCNPPVPTVSSRGREQAVRKS- 530
+++ +EE L P R++ +C + + EQ +R+
Sbjct: 1085 ---ELQQEEEQLLREE-PEKRRRQERERQCREEEEL------------QQEEEQLLREER 1128
Query: 531 EKERMREYQRELEEREEKLKKRPLLFERVAQKNARMAAEKHYSNTLKALGISDEFVSKKG 590
EK R +E +R+ E EE ++ L +K R E+ Y
Sbjct: 1129 EKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREE--------------- 1173
Query: 591 QSGKVLEYFNNQETKSVTEDKESFNEEEKIEERENGEENYFIDTNSQDSYKEKDEANE-- 648
E +E + + E++E +E ER+ EE + Y+++D+ ++
Sbjct: 1174 ------EELQQEEEQLLREEQEKRRQE---RERQYREEEELQRQKRKQRYRDEDQRSDLK 1224
Query: 649 ---ESEEEKSVEES 659
E E+E +V ++
Sbjct: 1225 WQWEPEKENAVRDN 1238
Score = 42.4 bits (98), Expect = 0.001
Identities = 96/576 (16%), Positives = 219/576 (38%), Gaps = 114/576 (19%)
Query: 114 EKMYQDKLHLKEVQPVVIREDSLSDSSRSVSEKNSYHPVSLMTSFSEPDLGQSSSLYVSS 173
E+ Y+++ L++ + ++RE+ + R + Y + E LG+
Sbjct: 927 ERQYREEEQLQQEEEQLLREER--EKRRRQERERQYRKDKKLQQKEEQLLGEEPE----- 979
Query: 174 SEEELPNLEKEYPRKNRMMTYAKELINNMWTDFCVEDYIRCKDTGFHAAEKRRKKRKEWV 233
+ EK+Y + + ++L+ E+ +++R+EW
Sbjct: 980 -KRRRQEREKKYREEEELQQEEEQLLRE---------------------EREKRRRQEWE 1017
Query: 234 PTITVPEPFQM----MIREQKKK------EESMKSKSDIEMVHKAL--------KKQEED 275
+ Q ++RE+++K E + + +++ + L ++QE +
Sbjct: 1018 RQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELE 1077
Query: 276 PEYKKKFRANPVPASVFLPLYHDLVKQKEERRRSLKE---KSKEALLASQKPFKFIAREE 332
+Y+K+ + L ++ E+RRR +E + +E L ++ RE+
Sbjct: 1078 RQYRKEEELQQEEEQL-------LREEPEKRRRQERERQCREEEELQQEEEQLLREEREK 1130
Query: 333 QKRAAREKQLRDFLKYKKKTNRFKARPIPRSTYGSTTNDKLKEEELYRNLRTQLRAQEHL 392
++R E+Q R+ + +++ + R P +K + +EL R Q R +E L
Sbjct: 1131 RRRQELERQYREEEEVQQEEEQL-LREEP---------EKRRRQELER----QYREEEEL 1176
Query: 393 QNSSPLPCRSACGCRNPRCPEQAVKLKCKHKVRCPTPDFEDLPERYQKHLSEHKSPKLLT 452
Q R E+ K + + + + + +R Q++ E + L
Sbjct: 1177 QQEEEQLLR-----------EEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKW 1225
Query: 453 VCKPFDLHASPHASIKREKILADIEADEENLKETRWPYLSPRRKSPVRCAGVNPVPCNCN 512
+P +++ K+ + E ++ L R+ +
Sbjct: 1226 QWEP-----EKENAVRDNKVYCK-GRENEQFRQLEDSQLRDRQSQQ-----------DLQ 1268
Query: 513 PPVPTVSSRGREQAVRK---------SEKERMREYQRELEEREEK-LKKRPLLFERVAQK 562
+ R REQ R+ E++ RE Q+E + R+ K +++ LL E +K
Sbjct: 1269 HLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEK 1328
Query: 563 NARMAAEKHYSNTLKALGISDEFVSKKGQSGKVLEYFNNQETKSVTEDKESFNEEEKIEE 622
R ++ + + L +E ++ + + F +E + + ++ EE+++
Sbjct: 1329 RRRQETDRKFREEEQLLQEREEQPLRRQERDR---KFREEELRHQEQGRKFLEEEQRLRR 1385
Query: 623 RENGEENYFIDTNSQDSYKEKDEANEESEEEKSVEE 658
+E E F+ Q +E+++ + + K EE
Sbjct: 1386 QE--RERKFLKEEQQLRCQEREQQLRQDRDRKFREE 1419
Score = 42.4 bits (98), Expect = 0.001
Identities = 111/586 (18%), Positives = 219/586 (37%), Gaps = 106/586 (18%)
Query: 87 DIHHSNEEYFKKVEELKAAHIETMAKLEKMYQDKLHLKEVQPVVIREDSLSDSSRSVSEK 146
D H EE ++ E+ +A + ++ EK ++RE+ R +++
Sbjct: 1290 DRHFPEEEQLEREEQKEAKRRDRKSQEEKQ-------------LLREEREEKRRRQETDR 1336
Query: 147 NSYHPVSLMTSFSEPDLGQSSSLYVSSSEE--------ELPNLEKEYPRKNRMMTYAKEL 198
L+ E L + EE + E+ R+ R + KE
Sbjct: 1337 KFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKE- 1395
Query: 199 INNMWTDFCVEDYIRCKDTGFHAAEKRRKKRKEWVPTITVPEPFQMMIREQKKKEESMKS 258
E +RC++ + R +K +E ++ E R++K +EE +
Sbjct: 1396 ----------EQQLRCQEREQQLRQDRDRKFREEEQQLSRQE------RDRKFREEEQQV 1439
Query: 259 KSDIEMVHKALKKQEE-DPEYKKKFRANPVPASVFLPLYHDLVKQKEERRRSLKEKSKEA 317
+ E K L+++++ E +KFR L++++EE++ +E+ ++
Sbjct: 1440 RRQ-ERERKFLEEEQQLRQERHRKFREE-----------EQLLQEREEQQLHRQERDRKF 1487
Query: 318 LLASQKPFKFIAREEQKRAAREKQLRD------FLKYKKKTNRFKARPIPRSTYGSTTND 371
L Q+ + R+E+ R RE++LR FL+ +++ +R + +
Sbjct: 1488 LEEEQQ----LRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQR------------ 1531
Query: 372 KLKEEELYRNLRTQLRAQEHLQNSSPLPCRSACGCRNPRCPEQAVKLKCKHKVRCPTPDF 431
K +EE + LR Q R Q+ Q+ R R R +Q + + K R
Sbjct: 1532 KFLQEE--QQLRRQERGQQRRQDRDR-KFREEEQLRQEREEQQLSRQERDRKFRLEEQKV 1588
Query: 432 EDLPERYQKHLSEHKSPKLLTVCKPFDLHASPHASIKREKILADIEADEENLKETRWPYL 491
E+ +K + + + L R++ DE+ L+E L
Sbjct: 1589 RR-QEQERKFMEDEQQ-----------LRRQEGQQQLRQERDRKFREDEQLLQEREEQQL 1636
Query: 492 SPRRKSPVRCAGVNPVPCNCNPPVPTVSSRGREQAVRKSEKERMREYQRELEEREE---K 548
+ + P + + REQ +R + RE ++ L+E EE +
Sbjct: 1637 HRQERDR-----------KFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLR 1685
Query: 549 LKKRPLLFERVAQKNARMAAEKHYSNTLKALGISDEFVSKKGQSGKVLEYFNNQETKSVT 608
++R F Q+ R E+ + + L + + +K + + L QE
Sbjct: 1686 RQERDRKFREEEQQLRRQERERKFLQEEQQLRRQE--LERKFREEEQLRQETEQEQLRRQ 1743
Query: 609 EDKESFNEEEKIEERENGEENYFIDTNSQDSYKEKDEANEESEEEK 654
E EEE++ R EE ++E+++ +E EE++
Sbjct: 1744 ERYRKILEEEQL--RPEREEQQLRRQERDRKFREEEQLRQEREEQQ 1787
Score = 42.0 bits (97), Expect = 0.002
Identities = 108/584 (18%), Positives = 227/584 (38%), Gaps = 124/584 (21%)
Query: 112 KLEKMYQDKLHLKEVQPVVIREDSLSDSSRSVSEKNSYHPVSLMTSFSEPDLGQSSSLYV 171
+LE+ Y+++ +++ + ++RE+ + R + Y E +L Q
Sbjct: 1135 ELERQYREEEEVQQEEEQLLREEP--EKRRRQELERQYR--------EEEELQQE----- 1179
Query: 172 SSSEEELPNLEKEYPRKNRMMTYAKELINNMWTDFCVEDYIRCKDTGFHAAEKRRKKRK- 230
EE+L E+E R+ R Y +E E+ R K + E +R K
Sbjct: 1180 ---EEQLLREEQEKRRQERERQYREE-----------EELQRQKRKQRYRDEDQRSDLKW 1225
Query: 231 EWVPTITVP-------------EPFQMMIREQKKKEESMKSKSDIEMVHKALKKQEEDPE 277
+W P E F+ + Q + +S + + + +++E
Sbjct: 1226 QWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRR 1285
Query: 278 YKKKFRANPVPASVFLPLYHDLVKQKEERRRSLKEKSKEALLASQKPFKFIAREEQKRAA 337
++++ R P + + +QKE +RR K + ++ LL ++ K +E ++
Sbjct: 1286 WQQRDRHFPEEEQL------EREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFR 1339
Query: 338 REKQL-----RDFLKYKKKTNRFKARPIPRSTYGSTTNDKLKEEELYRNLRTQLRAQEHL 392
E+QL L+ +++ +F+ + G K EEE + LR Q R ++ L
Sbjct: 1340 EEEQLLQEREEQPLRRQERDRKFREEELRHQEQGR----KFLEEE--QRLRRQERERKFL 1393
Query: 393 QNSSPLPC----RSACGCRNPRCPEQAVKLKCKHKVRCPTPDFEDL--PERYQKHLSEHK 446
+ L C + R+ + E+ +L + + R + + + ER +K L E +
Sbjct: 1394 KEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQ 1453
Query: 447 SPKLLTVCKPFDLHASPHASIK-REKILADIEADEENLKETRWPYLSP----RRKSPVRC 501
L H + E++L + E + + +E +L RR+ R
Sbjct: 1454 -----------QLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDR- 1501
Query: 502 AGVNPVPCNCNPPVPTVSSRGREQAVRKSEKER----------MREYQRELEEREEKLKK 551
+ REQ +R E ER ++ QR+ + E++L++
Sbjct: 1502 -------------------KFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRR 1542
Query: 552 RPLLFERVAQKNARMAAEKHYSNTLKALGISDEFVSKKGQSGKVLEYFNNQETKSVTEDK 611
+ +R ++ + E+ + +S + +K F +E K +++
Sbjct: 1543 QERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRK---------FRLEEQKVRRQEQ 1593
Query: 612 E-SFNEEEKIEERENGEENYFIDTNSQDSYKEKDEANEESEEEK 654
E F E+E+ R+ G++ + ++E ++ +E EE++
Sbjct: 1594 ERKFMEDEQQLRRQEGQQQ--LRQERDRKFREDEQLLQEREEQQ 1635
Score = 41.6 bits (96), Expect = 0.002
Identities = 89/498 (17%), Positives = 195/498 (39%), Gaps = 69/498 (13%)
Query: 171 VSSSEEELPNLEKEYPRKNRMMTYAKELINNMWTDFCVEDYIRCKDTGFHAAEKRRKKRK 230
V EEE L++E P++ R + +E + + E RR++++
Sbjct: 252 VLRKEEE--KLQEEEPQRQRELQEEEEQLRKL-----------------ERQELRRERQE 292
Query: 231 EWVPTITVPEPFQMMIREQ---KKKEESMKSKSDIEMVHKALKKQEEDPEYKKKFRANPV 287
E + Q + REQ +K+EE + + + + ++Q+E+ ++ R
Sbjct: 293 E-------EQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEE 345
Query: 288 PASVFLPLYHDLVKQKEERRRSLKEKSKEALLASQKPFKF---IAREEQKRAA----REK 340
L + +++++ RR +E+ +E L ++ + + RE+Q R RE+
Sbjct: 346 RREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQ 405
Query: 341 QLRDFLKYKKKTNRFKARPIPRSTYGSTTNDKLKEEELYRNLRTQLRAQEHLQNSSPLPC 400
QLR + +++ + + + R K ++E + L+ + +
Sbjct: 406 QLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETE 465
Query: 401 RSACGCRNPRCPEQAVKLKCKHKVRCPTPDFEDLPERYQKHLSEHKSPKLLTVCKPFDLH 460
R R + + + + ++ + + ER ++ L + + K +
Sbjct: 466 RHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEE 525
Query: 461 ASPHASIKREKIL--ADIEADEENLKETRWPYLSPRRKSPVRCAGVNPVPCNCNPPVPTV 518
++ E+ L E E+ LK L R+ +
Sbjct: 526 ERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERR---------------EQRLKRE 570
Query: 519 SSRGREQAVRKSEKERMREYQRELEER-EEKLKKRPL-LFERVAQKNARMAAEKHYSNTL 576
R+Q +++ E+ R + +RE EER E++LK+ + E+ ++ R+ E+
Sbjct: 571 QEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERR 630
Query: 577 KALGISDEFVSKKGQSGKVLEYFNNQETKSVTEDKESFNEEEKIEERENGEENYFIDTNS 636
+ L S+E ++ Q + QE + +E EEE++E+R E
Sbjct: 631 QQLLKSEEQEERRQQQLR----REQQERREQRLKRE--EEEERLEQRLKREH-------- 676
Query: 637 QDSYKEKDEANEESEEEK 654
++ +E++ A EE E+ +
Sbjct: 677 EEERREQELAEEEQEQAR 694
Score = 40.8 bits (94), Expect = 0.004
Identities = 87/469 (18%), Positives = 177/469 (37%), Gaps = 76/469 (16%)
Query: 223 EKRRKKRKEWVPTITVPEPFQMMIREQKKKEESMKSKSDIEMVHKALKKQEEDPEYKKKF 282
++RR+KR+E + E EQ +K+E ++ + + ++++E E +++
Sbjct: 135 QRRRQKRQEQERELAEGE-------EQSEKQERLEQRDRQRRDEELWRQRQEWQEREERR 187
Query: 283 RANPVPASVFLPLYHDLVKQKEERRRSLKEKSKEALLASQKPFKFIAREEQKRAAREKQL 342
S + +++ RRR L E ++ REE+++ RE+Q
Sbjct: 188 AEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKG------------REEKQQQRRERQD 235
Query: 343 RDFLKYKKKTNRFKARPIPRSTYGSTTNDKLKEEELYRNLRTQLRAQEHLQNSSPLPCRS 402
R F + ++K R R T +KL+EEE R Q QE + L +
Sbjct: 236 RVFQEEEEKEWR------KRETVLRKEEEKLQEEEPQR----QRELQEEEEQLRKLERQE 285
Query: 403 ACGCRNPRCPEQAVKLKCKHKVRCPTPDFEDLPERYQKHLSEHKSPKLLTVCKPFDLHAS 462
R R E+ + + + + + E+ E+ ++ + + + + L
Sbjct: 286 L---RRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRRE 342
Query: 463 PHASIKREKILADIEADEENLKETRWPYLSPRRKSPVRCAGV------------------ 504
+RE+ L + +E ++ R RR+ +R
Sbjct: 343 QEE--RREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQ 400
Query: 505 --NPVPCNCNPPVPTVSSRGREQAVRKSEKERMREYQRELEEREEKLK----------KR 552
+ REQ +R+ ++E E + E E RE++LK KR
Sbjct: 401 LRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKR 460
Query: 553 PLLFERVAQKNARMAAEKHYSNTLKALGISDEFVSKKGQSGKVLEYFNNQETKSVTEDKE 612
ER Q+ + ++ + + E ++ Q + + ++ + + +
Sbjct: 461 EEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLK 520
Query: 613 SFNEEEKIEERENGEENYFIDTNSQDSYKEKDEANEE---SEEEKSVEE 658
EEE++++R E Q +E++E E+ EEEK +E+
Sbjct: 521 RQEEEERLQQRLRSE---------QQLRREQEERREQLLKREEEKRLEQ 560
Score = 36.2 bits (82), Expect = 0.099
Identities = 82/432 (18%), Positives = 169/432 (39%), Gaps = 95/432 (21%)
Query: 243 QMMIREQKKKEESMKSKSDIEMVHKALKKQEEDPEYKKKFRANPVPASVFLPLYHDLVKQ 302
Q + REQ+++ + + + + + ++QEE E + K + ++Q
Sbjct: 565 QRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREE------------VERLEQ 612
Query: 303 KEERRRSLK-----EKSKEALLASQKPFKFIAREEQKRAAREKQLRDFLKYKKKTNRFKA 357
+E R + LK E+ ++ LL S++ + R++Q R ++++ LK +++ R +
Sbjct: 613 EERREQRLKREEPEEERRQQLLKSEEQEE--RRQQQLRREQQERREQRLKREEEEERLEQ 670
Query: 358 RPIPRSTYGSTTNDKLKEEELYRNLRTQLRAQEHLQNSSPLPCRSACGCRNPRCPEQAVK 417
R + R +L EEE Q +A+E +++ R P+ +
Sbjct: 671 R-LKREHEEERREQELAEEE-------QEQARERIKS---------------RIPKWQWQ 707
Query: 418 LKCKHKVRCPTPDFEDLPERYQKHLSEHKSPKLLTVCKPFDLHASPHASIKREKILADIE 477
L+ + R + Q+ E + + + +L R+ +
Sbjct: 708 LESEADARQSKVYSRPRKQEGQRRRQEQEEKRRR---RESELQWQEEERAHRQ------Q 758
Query: 478 ADEENLKETRWPYLSPRRKSPVRCAGVNPVPCNCNPPVPTVSSRGREQAVRK-SEKERMR 536
+EE ++ W + + + R + PP+ REQ R+ +ER +
Sbjct: 759 QEEEQRRDFTWQWQAEEKSERGR------QRLSARPPL-------REQRERQLRAEERQQ 805
Query: 537 EYQRELEEREEKLKKRPLLFERVAQKNARMAAEKHYSNTLKALGISDEFVSKKGQSGKVL 596
QR L E EEK ++R ER +K + E +E + ++ ++ ++
Sbjct: 806 REQRFLPEEEEKEQRRRQRRER--EKELQFLEE-------------EEQLQRRERAQQLQ 850
Query: 597 EYFNNQETKSVTEDKESFNEEEK----------IEERENGEENYFIDTNSQDSYKEKDEA 646
E E + ED+E +E+ EER+ + Q+ +++ +
Sbjct: 851 E-----EEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQL 905
Query: 647 NEESEEEKSVEE 658
+E EEE EE
Sbjct: 906 LQEEEEELQREE 917
Score = 36.2 bits (82), Expect = 0.099
Identities = 97/542 (17%), Positives = 198/542 (36%), Gaps = 114/542 (21%)
Query: 175 EEELPNLEKEYPRKNRMMTYAKELINNMWTDFCVEDYIRCKDTGFHAAEKRRKKRKEWVP 234
+EE L+++ R+ ++ + W E+ R + T + + + RKE
Sbjct: 850 QEEEDGLQEDQERRRSQ----EQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQL 905
Query: 235 TITVPEPFQMMIREQKKKEESMKSKSDIEMVHKA-----------LKKQEEDPEYKKKFR 283
E Q RE+++++E + + E + + ++QE + +Y+K +
Sbjct: 906 LQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKK 965
Query: 284 ANPVPASVFLPLYHDLVKQKEERRRSLKEKSKEALLASQKPFKFIAREEQKRAAREKQLR 343
+ L ++ E+RRR +EK Q+ + + REE+++ R++ R
Sbjct: 966 LQQKEEQL-------LGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWER 1018
Query: 344 DFLKYKK---------KTNRFKARPIPRSTYGSTTNDKLKEEELY----------RNLRT 384
+ K + + R K R R + +EEE + L
Sbjct: 1019 QYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELER 1078
Query: 385 QLRAQEHLQNSSPLPCRSACGCRNPRCPEQAVKLKCKHKVRCPTPDFEDLPERYQKHLSE 444
Q R +E LQ R PE+ + + + + R + E+L + ++ L E
Sbjct: 1079 QYRKEEELQQEEEQLLREE--------PEKRRRQERERQCR----EEEELQQEEEQLLRE 1126
Query: 445 HKSPKLLTVCKPFDLHASPHASIKREKILADIEADEENLKETRWPYLSPRRKSPVRCAGV 504
+ + + + E++L + E ++ +E Y R + ++
Sbjct: 1127 EREKRRRQELER-QYREEEEVQQEEEQLLRE-EPEKRRRQELERQY---REEEELQ---- 1177
Query: 505 NPVPCNCNPPVPTVSSRGREQAVRKSEKERMREYQRELEEREE--KLKKRPLLFERVAQK 562
+ EQ +R+ +++R +E +R+ E EE + K++ + +
Sbjct: 1178 ----------------QEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRS 1221
Query: 563 NARMAAEKHYSNTLKALGISDEFVSKKGQS-------------------------GKVLE 597
+ + E N ++ D V KG+ G+ E
Sbjct: 1222 DLKWQWEPEKENAVR-----DNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQE 1276
Query: 598 YFNNQETKSVTEDKESFNEEEKIEERENGEENYFIDTNSQDSYKEKDEANEESEEEKSVE 657
QE + + F EEE++E E E + S +EK EE EE++ +
Sbjct: 1277 RDREQERRRWQQRDRHFPEEEQLEREEQKEAK----RRDRKSQEEKQLLREEREEKRRRQ 1332
Query: 658 ES 659
E+
Sbjct: 1333 ET 1334
Score = 36.2 bits (82), Expect = 0.099
Identities = 43/185 (23%), Positives = 86/185 (46%), Gaps = 24/185 (12%)
Query: 223 EKRRKKRKEWVPTITVPEPFQMMIREQKKK---EESMKSKSDIEMVHKALKKQEEDPEYK 279
++R +K E P + E Q + ++ +K EE + + + + L++QE D +++
Sbjct: 1639 QERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGE----EQQLRRQERDRKFR 1694
Query: 280 KKFRA--NPVPASVFLPLYHDLVKQKEERR----RSLKEKSKEALLASQKPFKFIAREEQ 333
++ + FL L +Q+ ER+ L++++++ L Q+ ++ I EEQ
Sbjct: 1695 EEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQ 1754
Query: 334 KRAAREKQLRDFLKYKKKTNRFKARPIPR------STYGSTTNDKLKEEELYRNLR--TQ 385
R RE+Q L+ +++ +F+ R ++ K +EEE R R Q
Sbjct: 1755 LRPEREEQQ---LRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQ 1811
Query: 386 LRAQE 390
LR Q+
Sbjct: 1812 LRPQQ 1816
Score = 35.8 bits (81), Expect = 0.13
Identities = 109/592 (18%), Positives = 219/592 (36%), Gaps = 103/592 (17%)
Query: 89 HHSNEEYFKKVEELKAAHIETMAK--LEKMYQDKLHLKEVQPVVIREDSLSDSSRSVSEK 146
+ EE ++ E+L ET + LE+ Y+ + L++ + ++RE+ R E+
Sbjct: 1050 YREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEP-EKRRRQERER 1108
Query: 147 NSYHPVSLMTSFSEPDLGQSSSLYVSSSEEELPNLEKEYPRKNRMMTYAKELINNMWTDF 206
E +L Q EE+L E+E R+ + +E
Sbjct: 1109 QCRE---------EEELQQE--------EEQLLREEREKRRRQELERQYRE--------- 1142
Query: 207 CVEDYIRCKDTGFHAAEKRRKKRKEWVPTITVPEPFQMMIREQKKKEESMKSKSDIEMVH 266
E+ ++ ++ E +++R+E E Q EQ +EE K + + E
Sbjct: 1143 --EEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQE-EEQLLREEQEKRRQERE--- 1196
Query: 267 KALKKQEEDPEYKKKFRANPVPASVFLPLYHDLVKQKEERRRSLK---EKSKEALLASQK 323
+ +++EE K+K R Y D E++R LK E KE + K
Sbjct: 1197 RQYREEEELQRQKRKQR------------YRD-----EDQRSDLKWQWEPEKENAVRDNK 1239
Query: 324 PFKFIAREEQKRAAREKQLRDF-----LKYKKKTNRFKARPIPRSTYGSTTNDKLKEEEL 378
+ EQ R + QLRD L++ + + R R + +EE+L
Sbjct: 1240 VYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQL 1299
Query: 379 YRNLRTQLRAQEHLQNSSPLPCRSACGCRNPRCPEQAVKLKCKHKVRCPTPDFEDLPERY 438
R + + + ++ R R + Q K + + + + E+ P R
Sbjct: 1300 EREEQKEAKRRDRKSQEEKQLLREE---REEKRRRQETDRKFREEEQL-LQEREEQPLRR 1355
Query: 439 QKHLSEHKSPKLLTVCKPFDLHASPHASIKREKILADIEADEENLKETRWPYLSPRRKSP 498
Q+ + + +L ++ E+ L E + + LKE + R+
Sbjct: 1356 QERDRKFREEELRH-------QEQGRKFLEEEQRLRRQERERKFLKEEQ-QLRCQEREQQ 1407
Query: 499 VRCAGVNPVPCNCNPPVPTVSSRGREQAVRKSEKERMREYQRELEEREEKLKKRPLLFER 558
+R + RE+ + S +ER R+++ E ++ + ++R L E
Sbjct: 1408 LR---------------QDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEE 1452
Query: 559 VAQKNARMAAEKHYSNTLKALGISDEFVSKKGQSGKVLE------------YFNNQETKS 606
+ R + L+ ++ + ++ + K LE F QE +S
Sbjct: 1453 QQLRQERHRKFREEEQLLQER--EEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRS 1510
Query: 607 VTEDKESFNEEEKIEERENGEENYFIDTNSQDSYKEKDEANEESEEEKSVEE 658
+++ EE+++ ++ + F+ Q +E+ + + + K EE
Sbjct: 1511 QEPERKFLEEEQQLHRQQ--RQRKFLQEEQQLRRQERGQQRRQDRDRKFREE 1560
Score = 31.2 bits (69), Expect = 3.2
Identities = 31/134 (23%), Positives = 60/134 (44%), Gaps = 16/134 (11%)
Query: 521 RGREQAVRKSEKERMREYQRELEEREEKLKKRPLLFERVAQKNARMAAEKHYSNTLKALG 580
R E+ + +++ +E +REL E EE+ +K+ ER+ Q++ + E+ + +
Sbjct: 127 RQLEEEPGQRRRQKRQEQERELAEGEEQSEKQ----ERLEQRDRQRRDEELWRQRQE--- 179
Query: 581 ISDEFVSKKGQSGKVLEYFNNQETKSVTEDKESFNEEEKIEERENGEENYFIDTNSQDSY 640
E ++ + + L+ ET+ D+E E +E R G E Q
Sbjct: 180 -WQEREERRAEE-EQLQSCKGHETEEF-PDEEQLRRRELLELRRKGRE------EKQQQR 230
Query: 641 KEKDEANEESEEEK 654
+E+ + + EEEK
Sbjct: 231 RERQDRVFQEEEEK 244
>gi|154759273 testis specific, 10 interacting protein [Homo sapiens]
Length = 556
Score = 55.1 bits (131), Expect = 2e-07
Identities = 28/80 (35%), Positives = 48/80 (60%), Gaps = 3/80 (3%)
Query: 516 PTVSSRGREQAVRKSEKERMREYQRELEEREEKLKKRPLLFERVAQKNARMAAEKHYSNT 575
P + R E+ +R+ E++R EYQ EL+ + +++ RP LF++ Q NAR+ + +S
Sbjct: 430 PGAAQRKLEE-LRRQERQRFAEYQAELQGIQHRVQARPFLFQQAMQANARLTVTRRFSQV 488
Query: 576 LKALGISDEFVSKKGQSGKV 595
L ALG+ +E ++GKV
Sbjct: 489 LSALGLDEE--QLLSEAGKV 506
>gi|125656165 THO complex 2 [Homo sapiens]
Length = 1593
Score = 52.0 bits (123), Expect = 2e-06
Identities = 83/385 (21%), Positives = 155/385 (40%), Gaps = 105/385 (27%)
Query: 270 KKQEEDPEYKKKFRANPVPASVFLPLYHDLVKQKEERRRSLKEKSKEALLASQKPFKFIA 329
K +E++ E K+K A A V L D ++ +E R + EK++E
Sbjct: 1273 KGKEKEKEKKEKTPATTPEARV---LGKDGKEKPKEERPNKDEKARET------------ 1317
Query: 330 REEQKRAAREKQLRDFLKYKK----KTNRFKARPIPRSTYGSTTNDKLKEEELYRNLRTQ 385
+E ++ +EK+ K+KK K +FK + + ++ KE R++ +
Sbjct: 1318 KERTPKSDKEKE-----KFKKEEKAKDEKFKTTVPNAESKSTQEREREKEPSRERDIAKE 1372
Query: 386 LRAQEHLQNSSPLPCRSACGCRNPRCPEQAVKLKCKHKVRCPTPDFEDLPERYQKHLSEH 445
++++E+++ P + K P D + PER QK
Sbjct: 1373 MKSKENVKGGEKTPVSGSL------------------KSPVPRSDIPE-PEREQKR---- 1409
Query: 446 KSPKLLTVCKPFDLHASP-HASIKREKILADIEADEENLKETRWPYLSPRRKSPVRCAGV 504
+ D H SP H+S ++ + IE E + K +
Sbjct: 1410 ---------RKIDTHPSPSHSSTVKDSL---IELKESSAK-----------------LYI 1440
Query: 505 NPVPCNCNPPVPTVSSRGREQAVRKSEKERMREYQRELEEREEKLKKR------------ 552
N P PP+ S+ +E+ + K + ++ RE RE E+++EK +K
Sbjct: 1441 NHTP----PPL----SKSKEREMDKKDLDKSRERSREREKKDEKDRKERKRDHSNNDREV 1492
Query: 553 -PLLFERVAQKNARMAAEKHYSNTLKALGISDEFVSKKGQSG-----KVLEYFNNQETKS 606
P L +R ++N M KH S + +E +K +S K + F +++
Sbjct: 1493 PPDLTKRRKEENGTMGVSKHKSESPCESPYPNEKDKEKNKSKSSGKEKGSDSFKSEKMDK 1552
Query: 607 VTED--KESFNEEEKIEERENGEEN 629
++ KES +++EKIE++E + +
Sbjct: 1553 ISSGGKKESRHDKEKIEKKEKRDSS 1577
Score = 34.3 bits (77), Expect = 0.38
Identities = 75/356 (21%), Positives = 135/356 (37%), Gaps = 71/356 (19%)
Query: 247 REQKKKEESMKSKSDIEMVHKALKKQ--EEDPEYKKKFRANP--VPASVFLPLYHDLVKQ 302
+E++KKE++ + + ++ K K++ EE P +K R P S D K+
Sbjct: 1277 KEKEKKEKTPATTPEARVLGKDGKEKPKEERPNKDEKARETKERTPKS-------DKEKE 1329
Query: 303 KEERRRSLKEKSKEALLASQKPFKFIAREEQKRAAREKQLRDFLKYKKKTNRFKARPIPR 362
K ++ K++ + + + + RE +K +RE+ + +K K+ + P+
Sbjct: 1330 KFKKEEKAKDEKFKTTVPNAESKSTQEREREKEPSRERDIAKEMKSKENVKGGEKTPVSG 1389
Query: 363 STYGSTTNDKLKEEELYRNLRTQLRAQEHLQNSSPLPCRSACGCRNPRCPEQAVKLKCKH 422
S + E E R Q R + ++ P P S+ + ++LK
Sbjct: 1390 SLKSPVPRSDIPEPE-----REQKRRK---IDTHPSPSHSS------TVKDSLIELK--- 1432
Query: 423 KVRCPTPDFEDLPERYQKHLSEHKSPKLLTVCKPFDLHASPHASIKREKILADIEADEEN 482
E + Y H S DL S S +REK DE++
Sbjct: 1433 ---------ESSAKLYINHTPPPLSKSKEREMDKKDLDKSRERSREREK------KDEKD 1477
Query: 483 LKETRW----------PYLSPRRKSPVRCAGVNPVPCN--CNPPVPT--------VSSRG 522
KE + P L+ RRK GV+ C P P S G
Sbjct: 1478 RKERKRDHSNNDREVPPDLTKRRKEENGTMGVSKHKSESPCESPYPNEKDKEKNKSKSSG 1537
Query: 523 REQAVRKSEKERM-------REYQRELEEREEKLKKRPLLFERVAQKNARMAAEKH 571
+E+ + E+M ++ R +E+ EK +KR + +K+ + +++KH
Sbjct: 1538 KEKGSDSFKSEKMDKISSGGKKESRHDKEKIEKKEKRDSSGGKEEKKHHK-SSDKH 1592
>gi|46049114 M-phase phosphoprotein 1 [Homo sapiens]
Length = 1780
Score = 51.2 bits (121), Expect = 3e-06
Identities = 131/684 (19%), Positives = 261/684 (38%), Gaps = 139/684 (20%)
Query: 22 ITGARVAQYEREDPLKALAAAEAILEDEEEEKVAQPAGASADLNTSFSGVDEHAPISYED 81
I RV Q E L E L++E+EEK A+LN + +S +
Sbjct: 834 IEDIRVLQENNEGLRAFLLTIENELKNEKEEK--------AELNKQIVHFQQELSLSEK- 884
Query: 82 FVNFPDIHHSNEEYFKKVEELKAAHIETMAKLEKMYQDKLHLKEVQPVVIREDSLSDSSR 141
N K+V+++++ + +A+L Q + ++ + ++ + + ++R
Sbjct: 885 ---------KNLTLSKEVQQIQSNYDIAIAELH--VQKSKNQEQEEKIMKLSNEIETATR 933
Query: 142 SVSEKNSYHPVSLM-------------TSFSEPDLGQSSSLYVSSSEEELPNLEKEYPRK 188
S++ N+ + LM + S DL L S E+ LPN + +
Sbjct: 934 SIT--NNVSQIKLMHTKIDELRTLDSVSQISNIDLLNLRDLSNGSEEDNLPNTQLD---- 987
Query: 189 NRMMTYAKELINNMWTDFCVEDYIRCKDTGFHAAEKRRKKRKEWVPTITVPEPFQMMIRE 248
L+ N DY+ K + ++ ++ + E + +++
Sbjct: 988 ---------LLGN--------DYLVSKQVKEYRIQEPNRENSFHSSIEAIWEECKEIVKA 1030
Query: 249 QKKKEESMKS-KSDIEMVHKALKK-QEEDPEYKKKFRANPVPASVFLPLYHDLVKQKEER 306
KK ++ + IE + +K ++E+ K+K N DL+K+KE
Sbjct: 1031 SSKKSHQIEELEQQIEKLQAEVKGYKDENNRLKEKEHKNQ----------DDLLKEKETL 1080
Query: 307 RRSLKEKSKEALLASQKPFKFIAREEQKRAAREKQLRDFLKYKKKTNRFKA----RPIPR 362
+ LKE+ +E + + + E KRA E + YK K + + +
Sbjct: 1081 IQQLKEELQEKNVTLDVQIQHVV--EGKRALSELT-QGVTCYKAKIKELETILETQKVEC 1137
Query: 363 STYGSTTNDKLKEEELYRNLRTQLRA-QEHLQNSSPLPCRSACGCRNPRCPEQAVKLKCK 421
S D L++E + L L+ QEHLQ+S +N + +LK K
Sbjct: 1138 SHSAKLEQDILEKESIILKLERNLKEFQEHLQDS----------VKNTK-DLNVKELKLK 1186
Query: 422 HKVRCPTPDFEDLPERYQKHLSEHKSPKLLTVCKPFDLHASPHASIKREKILADIEADEE 481
++ T + +D+ Q E ++ + T +L AS S + + + AD++ EE
Sbjct: 1187 EEITQLTNNLQDMKHLLQLKEEEEETNRQETEKLKEELSAS---SARTQNLKADLQRKEE 1243
Query: 482 NLKETRWPYLSPRRKSPVRCAGVNPVPCNCNPPVPTVSSRGREQAVRKSEKERMREYQRE 541
+ + + +++ + +E +V + E + +R E
Sbjct: 1244 DYADLKEKLTDAKKQ---------------------IKQVQKEVSVMRDEDKLLRIKINE 1282
Query: 542 LEEREEKLKKRPLLFERVAQK------NARMA-AEKHYSNTLKALGISDEFVSK------ 588
LE+++ + + + +R Q+ N ++ A + Y K L + ++ +
Sbjct: 1283 LEKKKNQCSQELDMKQRTIQQLKEQLNNQKVEEAIQQYERACKDLNVKEKIIEDMRMTLE 1342
Query: 589 -----KGQSGKVLEYFNNQETKSVTE---------DKESFNEEEKIEERENGEENYFIDT 634
+ + +VLE + + TE D E+ N + +E EN + T
Sbjct: 1343 EQEQTQVEQDQVLEAKLEEVERLATELEKWKEKCNDLETKNNQRSNKEHENNTDVLGKLT 1402
Query: 635 NSQDSYKEKDEANEESEEEKSVEE 658
N QD +E E ++ +K +EE
Sbjct: 1403 NLQDELQE-SEQKYNADRKKWLEE 1425
>gi|7657671 upstream binding transcription factor, RNA polymerase I
isoform a [Homo sapiens]
Length = 764
Score = 49.3 bits (116), Expect = 1e-05
Identities = 118/598 (19%), Positives = 228/598 (38%), Gaps = 103/598 (17%)
Query: 90 HSNEEYFKKVEELKAAHI-ETMAKLEKMYQDKLHLKEVQPVVIREDSLSDSSRSVSEKNS 148
H + Y K + + +++ K DK LK + + + + R +K
Sbjct: 209 HEKKVYLKVRPDATTKEVKDSLGKQWSQLSDKKRLKWIHKALEQRKEYEEIMRDYIQK-- 266
Query: 149 YHPVSLMTSFSEPDLGQSSSLYVSSSEEELPNLEKEYPRK---NRMMTYAKELINNMWTD 205
HP + SE + +S+ ++ +E +L + P K N Y EL+ NM
Sbjct: 267 -HPE---LNISEEGITKST---LTKAERQLKDKFDGRPTKPPPNSYSLYCAELMANMKDV 319
Query: 206 FCVEDYIRCKDTGFHAAEKRR--------KKRKEWVPTI-----TVPEPFQMMIREQKKK 252
E + C ++K + +K+K++ + ++PE Q + ++K
Sbjct: 320 PSTERMVLCSQQWKLLSQKEKDAYHKKCDQKKKDYEVELLRFLESLPEEEQQRVLGEEKM 379
Query: 253 EESMKSKSDIEMVHKALKKQEEDPEYKKKFRANPVPASVFLPLYHDLVKQKEERRRSLKE 312
K ++ K ++ + K K PV A EE+RR L+E
Sbjct: 380 LNINKKQATSPASKKPAQEGGKGGSEKPK---RPVSAMFIF---------SEEKRRQLQE 427
Query: 313 KSKEALLASQKPFKFIAREEQKRAAREKQLRDFLKYKKKTNRFKARPIPRSTYGSTTNDK 372
+ E L+ + + +AR + ++K KYK + KA+ + K
Sbjct: 428 ERPE--LSESELTRLLARMWNDLSEKKKA-----KYKAREAALKAQSERKPGGEREERGK 480
Query: 373 LKEEELYRNLRTQLRAQEHLQNSSPLPCRSACGCRNPRCPEQAVK-----------LKCK 421
L E + RA+E Q +S G R VK ++ K
Sbjct: 481 LPE--------SPKRAEEIWQ-------QSVIGDYLARFKNDRVKALKAMEMTWNNMEKK 525
Query: 422 HKVRCPTPDFEDLPERYQKHLSEHKSPKLLT-VCKPFDLHASPHASIKREKILADIEADE 480
K+ ED +RY++ LSE ++P T K P K+ + + +
Sbjct: 526 EKLMWIKKAAED-QKRYERELSEMRAPPAATNSSKKMKFQGEP----KKPPMNGYQKFSQ 580
Query: 481 ENLKETRWPYLSPRRKSPVRCAGVNPVPCNCNPPVPTVSSRGREQAVRKSEKERMREYQR 540
E L +L + + V R Q + +S+KE Y++
Sbjct: 581 ELLSNGELNHLPLKERM--------------------VEIGSRWQRISQSQKEH---YKK 617
Query: 541 ELEEREEKLKKRPLLFERVAQKNARMAAEKHYSNTLKALGISDEFVSKKGQSGKVLEYFN 600
EE++++ K L+ + R A +++ SN K++ + +S +
Sbjct: 618 LAEEQQKQYKVHLDLWVKSLSPQDRAAYKEYISNKRKSM---TKLRGPNPKSSRTTLQSK 674
Query: 601 NQETKSVTEDKESFNEEEKIEERENGEENYFIDTNSQDSYKEKDEANEESEEEKSVEE 658
++ + ED++ +E+E+ E+ ENG+ + +S+ S +++ E +E+EE+ E+
Sbjct: 675 SESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDED 732
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 48.5 bits (114), Expect = 2e-05
Identities = 81/453 (17%), Positives = 193/453 (42%), Gaps = 59/453 (13%)
Query: 224 KRRKKRKEWVPTITVPEPFQMMIREQKKK----EESMKSKSDIEMVHKALKKQEEDPEYK 279
++ +K +EW I E IREQ++K EE M+ + ++ + +++E+ ++
Sbjct: 304 RQEEKIQEWEEKIQEQEE---KIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWE 360
Query: 280 KKFRANPVPASVF-----LPLYHDLVKQKEERRRSLKEKSKEALLASQKPFKFIA----R 330
K+ + ++ + +++ +KEE+ R L+EK E ++ K R
Sbjct: 361 KEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIR 420
Query: 331 EEQKRAAREKQL---RDFLKYKKKTNRFKARPIPRSTYGSTTNDKLKEEELYRNLRTQLR 387
E++KR +E ++ + ++ +++ R + + + R +K++EEE + R
Sbjct: 421 EQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWR 480
Query: 388 AQEHLQNSSPLPCRSACGCRNPRCPEQAVKL-KCKHKVRCPTPDFEDLPERYQKHLSEHK 446
+E + + + + EQ K+ K + KV + E+ ++ E
Sbjct: 481 QEEKIHEQEEI------WRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQ-EEKM 533
Query: 447 SPKLLTVCKPFDLHASPHASIKREKILADIEADEENLKETRWPYLSPRRKSPVRCAGVNP 506
+ + + ++ ++EKI + + E+ ++ W R++ +R
Sbjct: 534 WRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQ--EDKMW-----RQEEKIR------ 580
Query: 507 VPCNCNPPVPTVSSRGREQAVRKSEKE-RMREYQRELEEREEKLKKRPLLFERVAQKNAR 565
V + REQ ++ E+E +M + + ++ E+EEK++++ E++ ++ +
Sbjct: 581 ---EQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQE---EKIREQEEK 634
Query: 566 MAAEKHYSNTLKALGISDEFVSKKGQSGKVLEYFNNQETKSVTEDKESFNEEEKIEEREN 625
+ ++ + ++ + G+ E QE K +++ + +EEKI E+E
Sbjct: 635 IREQEEMTQ------------EQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEK 682
Query: 626 GEENYFIDTNSQDSYKEKDEANEESEEEKSVEE 658
Q+ ++ E +EEK E+
Sbjct: 683 KIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQ 715
Score = 44.3 bits (103), Expect = 4e-04
Identities = 80/491 (16%), Positives = 203/491 (41%), Gaps = 61/491 (12%)
Query: 171 VSSSEEELPNLEKEYPRKNRMMTYAKELINNMWTDFCVEDYIRCKDTGFHAAEKRRKKRK 230
+ EE++ E++ + M +E+ MW E+ +R ++ E++ ++++
Sbjct: 316 IQEQEEKIREQEEKIREQEEKMRRQEEM---MWEK---EEKMRRQEEMMWEKEEKMRRQE 369
Query: 231 E--WVPTITVPEPFQMMIREQKKKEESMKSKSDIEMVHKALKKQEEDPEYKKKFRANPVP 288
E W + +MM +++K E + + E + + +K++E+ + +++ +
Sbjct: 370 EMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQE 429
Query: 289 ASVFLPLYHDLVKQKEERRRSLKEKS--KEALLASQKPFKFIAREEQKRAAREKQLRDFL 346
A ++ + ++++EE+ R ++K +E + Q+ REE+KR +E+ R
Sbjct: 430 AKMWRQ--EEKIREQEEKIREQEKKMWRQEEKIHEQEKI----REEEKRQEQEEMWRQEE 483
Query: 347 KYKKKTNRFKARPIPRSTYGSTTNDKLKEEELYRNLRTQLRAQEHLQNSSPLPCRSACGC 406
K ++ ++ + + + +EE+++R +E ++ R
Sbjct: 484 KIHEQEEIWRQK---EKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWR----- 535
Query: 407 RNPRCPEQAVKLKCKHKVRCPTPDFEDLPERYQKHLSEHKSPKLLTVCKPFDLHASPHAS 466
+ + EQ + + K+ +E+ + Q+ + K+
Sbjct: 536 QEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKI---------REQEEKV 586
Query: 467 IKREKILADIEADEENLKETRWPYLSPRRKSPVRCAGVNPVPCNCNPPVPTVSSRGREQA 526
++E+ + + E + +E W R+ + + +E+
Sbjct: 587 WRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKI-------------------QEQEEK 627
Query: 527 VRKSEKERMREYQRELEEREEKLKKRPLLFERVAQKNARMAAEKHYSNTLKALGISDEFV 586
+R+ E E++RE + +E+EEK+ ++ E++ ++ +M E+ + + I ++
Sbjct: 628 IREQE-EKIREQEEMTQEQEEKMGEQE---EKMCEQEEKMQ-EQEETMWRQEEKIREQEK 682
Query: 587 SKKGQSGKVLEYFNNQETKSVTEDKESFNEEEKIEERENGEENYFIDTNSQDSYKEKDEA 646
+ Q K+ E QE ++++ + +EEK+ E+E + Q+ + E
Sbjct: 683 KIREQEEKIRE----QEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEV 738
Query: 647 NEESEEEKSVE 657
+EEK E
Sbjct: 739 RLRQQEEKMQE 749
Score = 42.7 bits (99), Expect = 0.001
Identities = 28/140 (20%), Positives = 68/140 (48%), Gaps = 7/140 (5%)
Query: 523 REQAVRKSEKERMREYQRELEEREEKLKKRPLLFERVAQK--NARMAAEKHYSNTLKALG 580
REQ R+ ++ +M + ++ E+EEK++++ R +K E+ + +
Sbjct: 420 REQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMW 479
Query: 581 ISDEFVSKKGQSGKVLEYFNNQETKSVTEDKESFNEEEKIEERENGEENYFIDTNSQDSY 640
+E + ++ + + E + QE K ++++ + +EEKI E+E I + +
Sbjct: 480 RQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEK-----IREQEEKMW 534
Query: 641 KEKDEANEESEEEKSVEESH 660
+++++ E+ E + E+ H
Sbjct: 535 RQEEKIREQEEMWREEEKMH 554
Score = 41.6 bits (96), Expect = 0.002
Identities = 45/261 (17%), Positives = 112/261 (42%), Gaps = 20/261 (7%)
Query: 93 EEYFKKVEELKAAHIETMAKLEKMYQDKLHLKEVQPVVIREDSLSDSSRSVSEKNSYHPV 152
EE ++ E+ + + + EK+ + + ++E + + R++ + E+
Sbjct: 416 EEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQ 475
Query: 153 SLMTSFSEPDLGQSSSLY-----VSSSEEELPNLEKEYPRKNRMMTYAKELINN----MW 203
M E + + ++ + EE++ E++ R+ + +E I MW
Sbjct: 476 EEMWR-QEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMW 534
Query: 204 TDFCVEDYIRCKDTGFHAAEKRRKKRKEWVPTITVPEPFQMMIREQKKKEESMKSKSDIE 263
E+ IR ++ + EK ++ K W + +M +E+K +E+ K E
Sbjct: 535 RQ---EEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEE 591
Query: 264 MVHKALKKQEEDPEYKKKFRANPVPASVFLPLYHDLVKQKEERRRSLKEKSKEALLASQK 323
+ + +K++E E K + + ++++EE+ R +EK +E +Q+
Sbjct: 592 KIREQEEKRQEQEEKMWKQEEK-------IREQEEKIQEQEEKIREQEEKIREQEEMTQE 644
Query: 324 PFKFIAREEQKRAAREKQLRD 344
+ + +E+K +E+++++
Sbjct: 645 QEEKMGEQEEKMCEQEEKMQE 665
Score = 38.1 bits (87), Expect = 0.026
Identities = 46/256 (17%), Positives = 114/256 (44%), Gaps = 19/256 (7%)
Query: 88 IHHSNEEYFKKVEELKAAHIETMAKLEKMYQDKLHLKEVQPVVIREDSLSDSSRSVSEKN 147
I E+ +++ E+++ + + EKM++ + ++E + + E+ + + + E+
Sbjct: 505 IRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEK 564
Query: 148 SYHPVSLMTSFSEPDLGQSSSLYVSSSEEELPNLEKEYPRKNRMMTYAKELINNMWTDFC 207
M E Q ++ EE++ E++ + M +E I
Sbjct: 565 RQEQEDKMWRQEEKIREQEEKVW--RQEEKIREQEEKRQEQEEKMWKQEEKIREQ----- 617
Query: 208 VEDYIRCKDTGFHAAEKRRKKRKEWVPTITVPEPFQMMIREQKKKEESMKSKSDIEMVHK 267
E+ I+ ++ E++ ++++E +T + +M +E+K E+ K + E + +
Sbjct: 618 -EEKIQEQEEKIREQEEKIREQEE----MTQEQEEKMGEQEEKMCEQEEKMQEQEETMWR 672
Query: 268 ALKKQEEDPEYKKKFRANPVPASVFLPLYHDLVKQKEERRRSLKEKSKEALLASQKPFKF 327
++E+ E +KK R + ++++++EE+ +EK E Q+ +
Sbjct: 673 ---QEEKIREQEKKIREQEEK----IREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEK 725
Query: 328 IAREEQKRAAREKQLR 343
+ R+E+K +E +LR
Sbjct: 726 MRRQEEKMWEQEVRLR 741
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 46.6 bits (109), Expect = 7e-05
Identities = 30/125 (24%), Positives = 66/125 (52%), Gaps = 3/125 (2%)
Query: 529 KSEKERMREYQRELEEREEKLKKRPLLFERVAQKNARMAAEKHYSNTLKALGISDEFVSK 588
+ ++E++RE + ++ E+EEK++++ + +K R E+ + + +E + +
Sbjct: 378 QEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQ--EEMMWEKEEKMRRQEEMMWE 435
Query: 589 KGQSGKVLEYFNNQETKSVTEDKESFNEEEKIEERENGEENYFIDTNSQDSYKEKDEANE 648
K + + LE +++ K + E +E EEEKI E+E +E ++ +E++E
Sbjct: 436 KEEKIRELEEKMHEQEK-IREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIR 494
Query: 649 ESEEE 653
E EE+
Sbjct: 495 EQEEK 499
Score = 42.0 bits (97), Expect = 0.002
Identities = 32/149 (21%), Positives = 71/149 (47%), Gaps = 12/149 (8%)
Query: 521 RGREQAVRKSEKERMREYQRELEEREEKLKKRPLLF---ERVAQKNARMAAEKHYSNTLK 577
R ++A ++E++RE + ++ E+EEK+ ++ E++ ++ R E+ + K
Sbjct: 472 RQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEK 531
Query: 578 ALGISDEFVSKKGQSGKVLEYFNNQETKSVTEDKESFNEEEKIEERENG--------EEN 629
+ +E +K + + E QE K ++++ ++EEKI E+E E
Sbjct: 532 -IREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQ 590
Query: 630 YFIDTNSQDSYKEKDEANEESEEEKSVEE 658
++ +E++E +E EE+ +E
Sbjct: 591 EEKIREQEEKIREQEEMTQEQEEKMGEQE 619
Score = 41.2 bits (95), Expect = 0.003
Identities = 29/141 (20%), Positives = 67/141 (47%), Gaps = 11/141 (7%)
Query: 523 REQAVRKSEKERMREYQRELEEREEKLKKRPLLFERVAQKNARMAAEKHYSNTLKALGIS 582
R++ + ++E+MR + + E+EEK++++ + +K + + H ++
Sbjct: 400 RQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIR----- 454
Query: 583 DEFVSKKGQSGKVLEY--FNNQETKSVTEDKESFNEEEKIEERENGEENYFIDTNSQDSY 640
E K+ + K+ E QE K ++++ +EEKI E+E + Q+
Sbjct: 455 -EQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKI 513
Query: 641 KEKDEANEESE---EEKSVEE 658
+E+++ E+ E +E+ + E
Sbjct: 514 REEEKRQEQEEMWRQEEKIRE 534
Score = 40.8 bits (94), Expect = 0.004
Identities = 82/439 (18%), Positives = 178/439 (40%), Gaps = 93/439 (21%)
Query: 224 KRRKKRKEWVPTITVPEPFQMMIREQKKK----EESMKSKSDIEMVHKALKKQEEDPEYK 279
++ +K +EW I E IREQ++K EE M+ + ++ + +++E+ ++
Sbjct: 365 RQEEKIQEWEEKIQEQEE---KIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWE 421
Query: 280 KKFRANPVPASVFLPLYHDLVKQKEERRRSLKEKSKEALLASQKPFKFIAREEQKRAARE 339
K+ + + +++ +KEE+ R L+EK E + I +E+KR E
Sbjct: 422 KEEK---------MRRQEEMMWEKEEKIRELEEKMHEQ--------EKIREQEEKRQEEE 464
Query: 340 KQLRDFLKYKKKTNRFKARPIPRSTYGSTTNDKLKEEELYRNLRTQLRAQEHLQNSSPLP 399
K ++ ++K +A+ + +K++E+E R +E + +
Sbjct: 465 K-----IREQEKRQEQEAKMWRQEEKIREQEEKIREQE-----EKMWRQEEKIHEQEKIR 514
Query: 400 CRSACGCRNPRCPEQAVKLKCKHKVRCPTPDFEDLPERYQK-HLSEHKSPKLLTVCKPFD 458
+ EQ + + K+R + E++ + +K H E K K
Sbjct: 515 -------EEEKRQEQEEMWRQEEKIR----EQEEIWRQKEKIHEQEEKIRK--------- 554
Query: 459 LHASPHASIKREKILADIEADEENLKETRWPYLSPRRKSPVRCAGVNPVPCNCNPPVPTV 518
++E+ + D E +E W R++ +R
Sbjct: 555 ---QEEKMWRQEEKMHDQEEKIREQEEKVW-----RQEEKIR------------------ 588
Query: 519 SSRGREQAVRKSEKERMREYQRELEEREEKLKKRPLLFERVAQKNARMAAEKHYSNTLKA 578
+E+ +R+ E E++RE + +E+EEK+ ++ E++ ++ +M ++ +
Sbjct: 589 ---EQEEKIREQE-EKIREQEEMTQEQEEKMGEQE---EKMCEQEEKMQEQEEKMRRQEE 641
Query: 579 LGISDEFVSKKGQSGKVLEYFNNQETKSVTEDKESFNEEEKIEERENGEENYFIDTNSQD 638
I ++ + Q K+ E QE ++++ + +EEK+ E+E + Q+
Sbjct: 642 K-IREQEKKIREQEEKIRE----QEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQE 696
Query: 639 SYKEKDEANEESEEEKSVE 657
+ E +EEK E
Sbjct: 697 EKMWEQEVRLRQQEEKMQE 715
Score = 40.0 bits (92), Expect = 0.007
Identities = 32/136 (23%), Positives = 62/136 (45%), Gaps = 2/136 (1%)
Query: 523 REQAVRKSEKERMREYQRELEEREEKLKKRPLLFERVAQKNARMAAEKHYSNTLKALGIS 582
+E+ +RK E E+M + ++ ++EEK++++ R +K R EK K
Sbjct: 548 QEEKIRKQE-EKMWRQEEKMHDQEEKIREQEEKVWRQEEK-IREQEEKIREQEEKIREQE 605
Query: 583 DEFVSKKGQSGKVLEYFNNQETKSVTEDKESFNEEEKIEERENGEENYFIDTNSQDSYKE 642
+ ++ + G+ E QE K ++++ +EEKI E+E Q+ +
Sbjct: 606 EMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQ 665
Query: 643 KDEANEESEEEKSVEE 658
+ E +EEK E+
Sbjct: 666 EQEEKMWEQEEKMCEQ 681
Score = 38.5 bits (88), Expect = 0.020
Identities = 49/286 (17%), Positives = 124/286 (43%), Gaps = 34/286 (11%)
Query: 93 EEYFKKVEELKAAHIETMAKLEKMYQDKLH-LKEVQPVVIREDSLSDSSRSVSEKNSYHP 151
EE ++ EE+ E M + E+M +K ++E++ + ++ + + E+
Sbjct: 409 EEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIR- 467
Query: 152 VSLMTSFSEPDLGQSSSLYVSSSEEELPNLEKEYPRKNRMMTYAKELINNMWTDFCVEDY 211
E + Q + EE++ E++ + M +E I+ ++
Sbjct: 468 --------EQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHE-------QEK 512
Query: 212 IRCKDTGFHAAEKRRKKRKEWVPTITVPEPFQMMIREQKKKEESMKSKSDIEMVHKALKK 271
IR EKR+++ + W + E ++ +++K E+ K + E K ++
Sbjct: 513 IR-------EEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEE---KMWRQ 562
Query: 272 QEEDPEYKKKFRANPVPASVFLPLYHDLVKQKEERRRSLKEKSKEALLASQKPFKFIARE 331
+E+ + ++K R + ++++EE+ R +EK +E +Q+ + + +
Sbjct: 563 EEKMHDQEEKIREQEEKVW----RQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQ 618
Query: 332 EQKRAAREKQLRDFLKYKKKTNRFKARPIPRSTYGSTTNDKLKEEE 377
E+K +E+++++ ++K R + + + +K++E+E
Sbjct: 619 EEKMCEQEEKMQE---QEEKMRRQEEKIREQEKKIREQEEKIREQE 661
Score = 35.4 bits (80), Expect = 0.17
Identities = 48/260 (18%), Positives = 114/260 (43%), Gaps = 24/260 (9%)
Query: 93 EEYFKKVEELKAAHIETMAKLEKMYQDKLHLKEVQPVVIREDSLSDSSRSVSEKNSYHPV 152
EE ++ E+ + + + EK+ + + ++E + + R++ + E+
Sbjct: 463 EEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQ 522
Query: 153 SLMTSFSEPDLGQSSSLY-----VSSSEEELPNLEKEYPRKNRMMTYAKELINN----MW 203
M E + + ++ + EE++ E++ R+ M +E I +W
Sbjct: 523 EEMWR-QEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVW 581
Query: 204 TDFCVEDYIRCKDTGFHAAEKRRKKRKEWVPTITVPEPFQMMIREQKKKEESMKSKSDIE 263
E+ IR ++ E++ ++++E +T + +M +E+K E+ K + E
Sbjct: 582 RQ---EEKIREQEEKIREQEEKIREQEE----MTQEQEEKMGEQEEKMCEQEEKMQ---E 631
Query: 264 MVHKALKKQEEDPEYKKKFRANPVPASVFLPLYHDLVKQKEERRRSLKEKSKEALLASQK 323
K +++E+ E +KK R + ++++++EE+ +EK E Q+
Sbjct: 632 QEEKMRRQEEKIREQEKKIREQEEK----IREQEEMMQEQEEKMWEQEEKMCEQEEKMQE 687
Query: 324 PFKFIAREEQKRAAREKQLR 343
+ + R+E+K +E +LR
Sbjct: 688 QEEKMRRQEEKMWEQEVRLR 707
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 46.2 bits (108), Expect = 1e-04
Identities = 29/126 (23%), Positives = 67/126 (53%), Gaps = 5/126 (3%)
Query: 529 KSEKERMREYQRELEEREEKLKKRP-LLFERVAQKNARMAAEKHYSNTLKALGISDEFVS 587
+ ++E++RE + ++ E+EEK++++ +++E+ ++ R E + K + +
Sbjct: 317 QEQEEKIREQEEKIREQEEKMRRQEEMMWEK--EEKMRRQEEMMWEKEEKMRRLEEMMWE 374
Query: 588 KKGQSGKVLEYFNNQETKSVTEDKESFNEEEKIEERENGEENYFIDTNSQDSYKEKDEAN 647
K+ + ++ E + QE + E +E EEEKI E+E +E ++ +E++E
Sbjct: 375 KEEKIRELEEKMHEQE--KIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKI 432
Query: 648 EESEEE 653
E E++
Sbjct: 433 REQEKK 438
Score = 44.3 bits (103), Expect = 4e-04
Identities = 79/438 (18%), Positives = 174/438 (39%), Gaps = 86/438 (19%)
Query: 224 KRRKKRKEWVPTITVPEPFQMMIREQKKK----EESMKSKSDIEMVHKALKKQEEDPEYK 279
++ +K +EW I E IREQ++K EE M+ + ++ + +++E+ ++
Sbjct: 304 RQEEKIQEWEEKIQEQEE---KIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWE 360
Query: 280 KKFRANPVPASVFLPLYHDLVKQKEERRRSLKEKSKEALLASQKPFKFIAREEQKRAARE 339
K+ + + +++ +KEE+ R L+EK E + I +E+KR E
Sbjct: 361 KEEKMRRL---------EEMMWEKEEKIRELEEKMHEQ--------EKIREQEEKRQEEE 403
Query: 340 KQLRDFLKYKKKTNRFKARPIPRSTYGSTTNDKLKEEELYRNLRTQLRAQEHLQNSSPLP 399
K ++ ++K +A+ + +K++E+E + R +E + +
Sbjct: 404 K-----IREQEKRQEQEAKMWRQEEKIREQEEKIREQE-----KKMWRQEEKIHEQEKIR 453
Query: 400 CRSACGCRNPRCPEQAVKLKCKHKVRCPTPDFEDLPERYQKHLSEHKSPKLLTVCKPFDL 459
+ EQ + + K+R + E +++ H+ K+
Sbjct: 454 -------EEEKRQEQEEMWRQEEKIR-------EQEEIWRQKEKMHEQEKI--------- 490
Query: 460 HASPHASIKREKILADIEADEENLKETRWPYLSPRRKSPVRCAGVNPVPCNCNPPVPTVS 519
++E+ + D E +E W R++ +R
Sbjct: 491 RKQEEKVWRQEEKMHDQEEKIREQEEKMW-----RQEEKIR------------------- 526
Query: 520 SRGREQAVRKSEKERMREYQRELEEREEKLKKRPLLFERVAQKNARMAAEKHYSNTLKAL 579
+E+ +R+ E E++RE + ++E+EEK+ ++ + Q+ R EK K
Sbjct: 527 --EQEEKIREQE-EKIREQEEMMQEQEEKMGEQEEKMQE--QEKMRRQEEKIREQEEKIR 581
Query: 580 GISDEFVSKKGQSGKVLEYFNNQETKSVTEDKESFNEEEKIEERENGEENYFIDTNSQDS 639
++ ++ + + E QE ++++ + +EEK+ E+E + Q+
Sbjct: 582 EQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEE 641
Query: 640 YKEKDEANEESEEEKSVE 657
+ E +EEK E
Sbjct: 642 KMWEQEVRLRQQEEKMQE 659
Score = 42.7 bits (99), Expect = 0.001
Identities = 27/129 (20%), Positives = 72/129 (55%), Gaps = 6/129 (4%)
Query: 531 EKERMREYQRELEEREEKLKKRPLLFERVAQKNARMAAEKHYS-NTLKALGISDEFVSKK 589
++E+++E++ +++E+EEK++++ E++ ++ +M ++ + + +E + +K
Sbjct: 305 QEEKIQEWEEKIQEQEEKIREQE---EKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEK 361
Query: 590 GQSGKVLEYFNNQETKSVTEDKESFNEEEKIEERENGEENYFIDTNSQDSYKEKDEANEE 649
+ + LE ++ + + E +E +E+EKI E+E E+ + + +++ EA
Sbjct: 362 EEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQE--EKRQEEEKIREQEKRQEQEAKMW 419
Query: 650 SEEEKSVEE 658
+EEK E+
Sbjct: 420 RQEEKIREQ 428
Score = 42.7 bits (99), Expect = 0.001
Identities = 54/302 (17%), Positives = 128/302 (42%), Gaps = 44/302 (14%)
Query: 93 EEYFKKVEELKAAHIETMAKLEKMYQDKLH-LKEVQPVVIREDSLSDSSRSVSEKNSYHP 151
EE ++ EE+ E M +LE+M +K ++E++ + ++ + + E+
Sbjct: 348 EEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIR- 406
Query: 152 VSLMTSFSEPDLGQSSSLYVSSSEEELPNLEKEYPRKNRMMTYAKELINNMWTDFCVEDY 211
E + Q + EE++ E++ + + M +E I+ ++
Sbjct: 407 --------EQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHE-------QEK 451
Query: 212 IRCKDTGFHAAEKRRKKRKEWVPTITVPEPFQMMIREQKKKEESMKSKSDIEMVHKALKK 271
IR EKR+++ + W + E ++ +++K E+ K + K ++
Sbjct: 452 IR-------EEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQE----EKVWRQ 500
Query: 272 QEEDPEYKKKFRANPVPASVFLPLYHDLVKQKEERRRSLKEKSKEALLASQKPFKFIARE 331
+E+ + ++K R + + ++++EE+ R +EK +E Q+ + + +
Sbjct: 501 EEKMHDQEEKIREQEEK----MWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQ 556
Query: 332 EQKRAAREKQLRDFLKYKKKTNRFKARPIPRSTYGSTTNDKLKE-EELYRNLRTQLRAQE 390
E+K +EK R K +++ + + + +K++E EE ++R QE
Sbjct: 557 EEKMQEQEKMRRQEEKIREQEEKIREQ-----------KEKIREQEEKIWEQEEKIREQE 605
Query: 391 HL 392
+
Sbjct: 606 EM 607
Score = 40.0 bits (92), Expect = 0.007
Identities = 29/141 (20%), Positives = 66/141 (46%), Gaps = 11/141 (7%)
Query: 523 REQAVRKSEKERMREYQRELEEREEKLKKRPLLFERVAQKNARMAAEKHYSNTLKALGIS 582
R++ + ++E+MR + + E+EEK+++ + +K + + H ++
Sbjct: 339 RQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIR----- 393
Query: 583 DEFVSKKGQSGKVLEY--FNNQETKSVTEDKESFNEEEKIEERENGEENYFIDTNSQDSY 640
E K+ + K+ E QE K ++++ +EEKI E+E + Q+
Sbjct: 394 -EQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKI 452
Query: 641 KEKDEANEESE---EEKSVEE 658
+E+++ E+ E +E+ + E
Sbjct: 453 REEEKRQEQEEMWRQEEKIRE 473
Score = 39.3 bits (90), Expect = 0.012
Identities = 33/148 (22%), Positives = 73/148 (49%), Gaps = 23/148 (15%)
Query: 523 REQAVRKSEKERMREYQRELEEREEKLKKRPLLFERVAQKNARMAAEKHYSNTLKALGIS 582
+E+ +R+ E E++RE ++++ +EEK+ ++ E++ ++ R E+ + K
Sbjct: 421 QEEKIREQE-EKIREQEKKMWRQEEKIHEQ----EKIREEEKRQEQEEMWRQEEKIREQE 475
Query: 583 DEFVSK---------KGQSGKVL---EYFNNQETKSVTEDKESFNEEEKIEERENGEENY 630
+ + K + Q KV E ++QE K ++++ + +EEKI E+E
Sbjct: 476 EIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIR-- 533
Query: 631 FIDTNSQDSYKEKDEANEESEEEKSVEE 658
++ +E++E +E EE+ +E
Sbjct: 534 ----EQEEKIREQEEMMQEQEEKMGEQE 557
Score = 38.5 bits (88), Expect = 0.020
Identities = 33/137 (24%), Positives = 69/137 (50%), Gaps = 25/137 (18%)
Query: 523 REQAVRKSEKERMREYQRELEEREEKLKKRPLLFERVAQKNARMAAEKHYSNTLKALGIS 582
+E+ +R+ E E+M + ++ E+EEK++++ E++ ++ M ++ + +G
Sbjct: 507 QEEKIREQE-EKMWRQEEKIREQEEKIREQE---EKIREQEEMMQEQE------EKMGEQ 556
Query: 583 DEFVSKKGQSGKVLEYFNNQETKSVTEDKESFNE-EEKIEERENGEENYFIDTNSQDSYK 641
+E + ++ + + E QE K + E KE E EEKI E+E + +
Sbjct: 557 EEKMQEQEKMRRQEEKIREQEEK-IREQKEKIREQEEKIWEQE-------------EKIR 602
Query: 642 EKDEANEESEEEKSVEE 658
E++E +E EE+ +E
Sbjct: 603 EQEEMMQEQEEKMWEQE 619
Score = 38.1 bits (87), Expect = 0.026
Identities = 31/146 (21%), Positives = 69/146 (47%), Gaps = 18/146 (12%)
Query: 523 REQAVRKSEKERMREYQRELEEREEKLKKRPLLF----------ERVAQKNARMAAEKHY 572
REQ R+ ++ +M + ++ E+EEK++++ E++ ++ R E+ +
Sbjct: 406 REQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMW 465
Query: 573 SNTLKALGISDEFVSKKGQSGKVLEYFNNQETKSVTEDKESFNEEEKIEERENGEENYFI 632
K E + ++ + E QE K ++++ ++EEKI E+E E+ +
Sbjct: 466 RQEEKIR--EQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQE--EKMW-- 519
Query: 633 DTNSQDSYKEKDEANEESEEEKSVEE 658
++ +E++E E EE+ +E
Sbjct: 520 --RQEEKIREQEEKIREQEEKIREQE 543
Score = 33.9 bits (76), Expect = 0.49
Identities = 47/251 (18%), Positives = 110/251 (43%), Gaps = 28/251 (11%)
Query: 93 EEYFKKVEELKAAHIETMAKLEKMYQDKLHLKEVQPVVIREDSLSDSSRSVSEKNSYHPV 152
EE ++ E+ E + + EK+ +++ +E + + +E+ + + +K H
Sbjct: 429 EEKIREQEKKMWRQEEKIHEQEKIREEEKR-QEQEEMWRQEEKIREQEEIWRQKEKMHEQ 487
Query: 153 SLMTSFSEPDLGQSSSLYVSSSEEELPNLEKEYPRKNRMMTYAKELINNMWTDFCVEDYI 212
+ E Q ++ EE++ E++ R+ + +E I E+ I
Sbjct: 488 EKIRKQEEKVWRQEEKMH--DQEEKIREQEEKMWRQEEKIREQEEKIREQ------EEKI 539
Query: 213 RCKDTGFHAAEKRRKKRKEWVPTITVPEPFQMMIREQKKKEESMKSKSDIEMVHKALKKQ 272
R ++ E++ +++E + E +M +E+K +E+ K + E K +++
Sbjct: 540 REQEEMMQEQEEKMGEQEE-----KMQEQEKMRRQEEKIREQEEKIR---EQKEKIREQE 591
Query: 273 EEDPEYKKKFRANPVPASVFLPLYHDLVKQKEERRRSLKEKSKEALLASQKPFKFIAREE 332
E+ E ++K R ++++++EE+ +EK E Q+ + + R+E
Sbjct: 592 EKIWEQEEKIREQ-----------EEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQE 640
Query: 333 QKRAAREKQLR 343
+K +E +LR
Sbjct: 641 EKMWEQEVRLR 651
Score = 31.2 bits (69), Expect = 3.2
Identities = 54/319 (16%), Positives = 128/319 (40%), Gaps = 28/319 (8%)
Query: 49 EEEEKVAQPAGASADLNTSFSGVDEHAPISYEDFVNFPDIHHSNEEYFKKVEELKAAHIE 108
E+EEK+ + + +E E ++ EE +++EE+ E
Sbjct: 318 EQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEE 377
Query: 109 TMAKLEKMYQDKLHLKEVQPVVIREDSLSDSS-RSVSEKNSYHPVSLMTSFSEPDLGQSS 167
+ +LE+ ++ ++E + E+ + + R E + + E Q
Sbjct: 378 KIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEK 437
Query: 168 SLYVSSSEEELPNLEK-----------------EYPRKNRMMTYAKELINNMWTDFCVED 210
++ EE++ EK E R+ + KE ++ E+
Sbjct: 438 KMW--RQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEE 495
Query: 211 YIRCKDTGFHAAEK--RRKKRKEWVPTITVPEPFQMMIREQKKK---EESMKSKSDIEMV 265
+ ++ H E+ R ++ K W + E + IREQ++K +E M + + +M
Sbjct: 496 KVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQ-EEKIREQEEKIREQEEMMQEQEEKMG 554
Query: 266 HKALKKQEEDPEYKKKFRANPVPASVFLPLYHDLVKQKEERRRSLKEKSKEALLASQKPF 325
+ K QE++ +++ + + + ++++EE+ +EK +E Q+
Sbjct: 555 EQEEKMQEQEKMRRQEEKIREQEEKI--REQKEKIREQEEKIWEQEEKIREQEEMMQEQE 612
Query: 326 KFIAREEQKRAAREKQLRD 344
+ + +E+K +E+++++
Sbjct: 613 EKMWEQEEKMCEQEEKMQE 631
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 46.2 bits (108), Expect = 1e-04
Identities = 30/133 (22%), Positives = 70/133 (52%), Gaps = 5/133 (3%)
Query: 527 VRKSEKERMREYQRELEEREEKLKKRPLLFERVAQKNARMAAEKHYS-NTLKALGISDEF 585
+ + ++E+M + +++EREEK++++ E++ ++ +M ++ + + +E
Sbjct: 282 LNQQQEEKMWRQEEKIQEREEKIQEQE---EKIREQEEKMRRQEEMMWEKEEKMRRQEEM 338
Query: 586 VSKKGQSGKVLEYFNNQETKSVTEDKESFNEEEKIEERENGEENYFIDTNSQDSYKEKDE 645
+ +K + + LE +++ K + E +E EEEKI E+E +E ++ +E++E
Sbjct: 339 MWEKEEKIRELEEKMHEQEK-IREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEE 397
Query: 646 ANEESEEEKSVEE 658
E EE +E
Sbjct: 398 KIREQEEMMQEQE 410
Score = 43.1 bits (100), Expect = 8e-04
Identities = 31/129 (24%), Positives = 64/129 (49%), Gaps = 10/129 (7%)
Query: 531 EKERMREYQRELEEREEKLKKRPLLFERVAQKNARMAAEKHYSNTLKALGISDEFVSKKG 590
++E+M E + E++E+EEK++++ E++ ++ ++ ++ + + E K G
Sbjct: 416 QEEKMWEQEEEMQEQEEKMRRQE---EKIREQEKKIREQEEKIREQEEMMQEQE--EKMG 470
Query: 591 -QSGKVLEYFNNQETKSVTEDKESFNEEEKIEERENGEENYFIDTNSQDSYKEKDEANEE 649
Q GK+ E QE K ++++ +EEKI E+E Q+ ++ E
Sbjct: 471 EQEGKMCE----QEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMW 526
Query: 650 SEEEKSVEE 658
+EEK E+
Sbjct: 527 EQEEKMCEQ 535
Score = 42.0 bits (97), Expect = 0.002
Identities = 32/137 (23%), Positives = 65/137 (47%), Gaps = 13/137 (9%)
Query: 523 REQAVRKSEKERMREYQRELEEREEKLKKRPLLFERVAQKNARMAAEKHYSNTLKALGIS 582
+E+ +R+ E E+MR + + E+EEK++++ + +K + + H ++
Sbjct: 307 QEEKIREQE-EKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIR----- 360
Query: 583 DEFVSKKGQSGKVLEYFNNQETKSVTEDKESFNEEEKIEERENG-EENYFIDTNSQDSYK 641
E K+ + K+ E QE ++ + + +EEKI E+E E + ++
Sbjct: 361 -EQEEKRQEEEKIREQEKRQE-----QEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMG 414
Query: 642 EKDEANEESEEEKSVEE 658
E++E E EEE +E
Sbjct: 415 EQEEKMWEQEEEMQEQE 431
Score = 40.4 bits (93), Expect = 0.005
Identities = 32/139 (23%), Positives = 69/139 (49%), Gaps = 16/139 (11%)
Query: 523 REQAVRKSEKERMREYQRELEE------REEKLKKRPLLFERVAQKNARMAAEKHYSNTL 576
REQ ++ E+E++RE ++ E+ +EEK++++ E++ ++ M ++
Sbjct: 360 REQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQE---EKIREQEEMMQEQE------ 410
Query: 577 KALGISDEFV-SKKGQSGKVLEYFNNQETKSVTEDKESFNEEEKIEERENGEENYFIDTN 635
+ +G +E + ++ + + E QE K ++K+ +EEKI E+E +
Sbjct: 411 EKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMG 470
Query: 636 SQDSYKEKDEANEESEEEK 654
Q+ + EA + +EEK
Sbjct: 471 EQEGKMCEQEAKMQEQEEK 489
Score = 39.3 bits (90), Expect = 0.012
Identities = 58/277 (20%), Positives = 113/277 (40%), Gaps = 63/277 (22%)
Query: 100 EELKAAHIETMAKLEKMYQDK----LHLKEV-------------QPVVIREDSLSDSSRS 142
EELK + + KL+ + +K L++KE+ Q + D L +S
Sbjct: 205 EELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQS 264
Query: 143 VSEK-----------NSYHPVSLMTSFSEPDLGQSSSLYVSSSEEELPNLEKEYPRKNRM 191
VS K N + + + + Q + EE++ E++ R+ M
Sbjct: 265 VSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEM 324
Query: 192 MTYAKELINN----MWTDFCVEDYIRCKDTGFHAAEKRRKKRKEWVPTITVPEPFQMMIR 247
M +E + MW E+ IR + H EK R++ ++ + IR
Sbjct: 325 MWEKEEKMRRQEEMMWEK---EEKIRELEEKMHEQEKIREQEEK--------RQEEEKIR 373
Query: 248 EQKKKEESMKSKSDIEMVHKALKKQEEDPEYKKKFRANPVPASVFLPLYHDLVKQKEERR 307
EQ+K++E K +++E+ E ++K R ++++++EE+
Sbjct: 374 EQEKRQEQEA---------KMWRQEEKIREQEEKIREQ-----------EEMMQEQEEKM 413
Query: 308 RSLKEKSKEALLASQKPFKFIAREEQKRAAREKQLRD 344
+EK E Q+ + + R+E+K +EK++R+
Sbjct: 414 GEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIRE 450
Score = 38.5 bits (88), Expect = 0.020
Identities = 28/141 (19%), Positives = 68/141 (48%), Gaps = 7/141 (4%)
Query: 523 REQAVRKSEKERMREYQRELEEREEKLKKRPLLF----ERVAQKNARMAAE--KHYSNTL 576
+E+ +R+ E E++RE ++++ E+EEK++++ + E++ ++ +M + K
Sbjct: 430 QEEKMRRQE-EKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEE 488
Query: 577 KALGISDEFVSKKGQSGKVLEYFNNQETKSVTEDKESFNEEEKIEERENGEENYFIDTNS 636
K ++ ++ + + E QE ++++ + +EEK+ E+E +
Sbjct: 489 KMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRR 548
Query: 637 QDSYKEKDEANEESEEEKSVE 657
Q+ + E +EEK E
Sbjct: 549 QEEKMREQEVRLRQQEEKMQE 569
Score = 38.1 bits (87), Expect = 0.026
Identities = 33/138 (23%), Positives = 66/138 (47%), Gaps = 13/138 (9%)
Query: 523 REQAVRKSEKERMREYQRELEEREEKLKKRPLLFERVAQKNARM--AAEKHYSNTLKALG 580
RE + E+E++RE Q E + EEK++++ E+ ++ A+M EK K
Sbjct: 347 RELEEKMHEQEKIRE-QEEKRQEEEKIREQ----EKRQEQEAKMWRQEEKIREQEEKIRE 401
Query: 581 ISDEFVSKKGQSGKVLEYFNNQETKSVTEDKESFNEEEKIEERENGEENYFIDTNSQDSY 640
+ ++ + G+ E QE + ++++ +EEKI E+E ++
Sbjct: 402 QEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIR------EQEEKI 455
Query: 641 KEKDEANEESEEEKSVEE 658
+E++E +E EE+ +E
Sbjct: 456 REQEEMMQEQEEKMGEQE 473
Score = 37.4 bits (85), Expect = 0.044
Identities = 50/265 (18%), Positives = 115/265 (43%), Gaps = 32/265 (12%)
Query: 93 EEYFKKVEELKAAHIETMAKLEKMYQDKLH-LKEVQPVVIREDSLSDSSRSVSEKNSYHP 151
EE ++ EE+ E M + E+M +K ++E++ + ++ + + E+
Sbjct: 315 EEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIR- 373
Query: 152 VSLMTSFSEPDLGQSSSLYVSSSEEELPNLEKEYPRKNRMMTYAKELINN----MWTDFC 207
E + Q + EE++ E++ + MM +E + MW
Sbjct: 374 --------EQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEE 425
Query: 208 V----EDYIRCKDTGFHAAEKRRKKRKEWVPTITVPEPFQMMIREQKKKEES----MKSK 259
E+ +R ++ EK+ ++++E + E +MM +++K E + +
Sbjct: 426 EMQEQEEKMRRQEEKIREQEKKIREQEE-----KIREQEEMMQEQEEKMGEQEGKMCEQE 480
Query: 260 SDIEMVHKALKKQEED-PEYKKKFRANPVPASVFLPLYHDLVKQKEERRRSLKEKSKEAL 318
+ ++ + +++QEE E +KK R + ++++++EE+ +EK E
Sbjct: 481 AKMQEQEEKMRRQEEKIREQEKKIREQEEK----IREQEEMMQEQEEKMWEQEEKMCEQE 536
Query: 319 LASQKPFKFIAREEQKRAAREKQLR 343
Q+ + + R+E+K +E +LR
Sbjct: 537 EKMQEQEEKMRRQEEKMREQEVRLR 561
Score = 33.9 bits (76), Expect = 0.49
Identities = 39/189 (20%), Positives = 86/189 (45%), Gaps = 23/189 (12%)
Query: 175 EEELPNLEKEYPRKNRMMTYAKELINNMWTDFCVEDYIRCKDTGFHAAEKRRKKRKE--- 231
EE + E++ R+ MM +E I + ++ IR ++ EK R++ K
Sbjct: 322 EEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQ 381
Query: 232 ----WVPTITVPEPFQM------MIREQKKK-----EESMKSKSDIEMVHKALKKQEED- 275
W + E + M++EQ++K E+ + + +++ + +++QEE
Sbjct: 382 EAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKI 441
Query: 276 PEYKKKFRANPVPASVFLPLYHDLVKQKEERRRSLKEKSKEALLASQKPFKFIAREEQKR 335
E +KK R + ++++++EE+ + K E Q+ + + R+E+K
Sbjct: 442 REQEKKIREQEEK----IREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKI 497
Query: 336 AAREKQLRD 344
+EK++R+
Sbjct: 498 REQEKKIRE 506
>gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens]
Length = 1684
Score = 45.8 bits (107), Expect = 1e-04
Identities = 62/308 (20%), Positives = 124/308 (40%), Gaps = 42/308 (13%)
Query: 86 PDIHHSNEEYFKKVEELKAAHIETMAKLEKMYQDKLHLKEVQPVVIREDSLSDSSRSVSE 145
P + + K++EE IE + K K ++K++ +++ V ++ DSSR ++
Sbjct: 936 PSVKNDPLSSVKELEE----KIENLEKECKEKEEKIN--KIKLVAVKAKKELDSSRKETQ 989
Query: 146 KNSYHPVSLMTSFSEPDLGQSSSLYVSSSEEELPNLEKEYPRKNRMMTYAKELINNMWTD 205
SL SE D +S + E NL EY +++ + KE NN +
Sbjct: 990 TVKEELESLR---SEKDQLSASMRDLIQGAESYKNLLLEYEKQSEQLDVEKERANNF--E 1044
Query: 206 FCVEDYIRCKDTGFHAAEKRRKKRKEWVPTITVPEPFQMMIREQKKKEESMKSKSDIEMV 265
+ED R E ++ + I + ++ Q + + K+ D E+
Sbjct: 1045 HRIEDLTRQLRNSTLQCETINSDNEDLLARIETLQSNAKLLEVQILEVQRAKAMVDKELE 1104
Query: 266 HKALKKQEEDPEYKKKFRANPVPASVFLPLYHDLVKQKEERRRSLKEKSKEALLASQKPF 325
+ L+K+++ E+ V + EE + L +K K+ L + +
Sbjct: 1105 AEKLQKEQKIKEHA------------------TTVNELEELQVQL-QKEKKQLQKTMQEL 1145
Query: 326 KFIAREEQKRAAREKQLRDFLKYKKKTNRFKARPIPRSTYGSTTNDKLKEEELYRNLRTQ 385
+ + ++ Q+ ++ D+ + K+ N+ TN K E+L + ++ Q
Sbjct: 1146 ELVKKDAQQTTLMNMEIADYERLMKELNQ------------KLTNKNNKIEDLEQEIKIQ 1193
Query: 386 LRAQEHLQ 393
+ QE LQ
Sbjct: 1194 KQKQETLQ 1201
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 45.8 bits (107), Expect = 1e-04
Identities = 83/449 (18%), Positives = 186/449 (41%), Gaps = 50/449 (11%)
Query: 223 EKRRKKRKEWVPTITVPEP----FQMMIREQKKKEESMK---SKSDIEMVHKALKKQEED 275
E+ +KK E + + E Q+ ++E K+K E K + + + + +QEE+
Sbjct: 183 EELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEE 242
Query: 276 -PEYKKKFRANPVPASVFLPLYHDLVKQKEERRRSLKEKSKEALLASQKPFKFIAREEQK 334
E +KK R + + ++EER R + K +E ++ K + +E++
Sbjct: 243 LREQEKKIRKQ-----------EEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKE 291
Query: 335 RAAREKQLRDFLKYKKKTNRFKARPIPRSTYGSTTNDKLKEEELYRNLRTQLRAQEHLQN 394
+EK+LR+ K +++ + + + + + +EE+++R +L QE
Sbjct: 292 LREQEKELREQKKLREQEEQMQEQ--EEKMWEQEEKMREQEEKMWRQ-EERLWEQEKQMR 348
Query: 395 SSPLPCRSACGCRNPRCPEQAVKLKCKHKVRCPTPDFEDLPERYQKHLSEHKSPKLLTVC 454
R + R EQ +L+ K + + E+ Q+ + K +
Sbjct: 349 EQEQKMRD----QEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMRE- 403
Query: 455 KPFDLHASPHASIKREKILADIEADEENLKETRWPYLSPRRKSPVRCAGVNPVPCNCNPP 514
+ + K+E+ + E +E+ ++ R P + +
Sbjct: 404 EEETMREQEEKMQKQEENM--WEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEK 461
Query: 515 VPTVSSR-GREQAVRKSEKERMREYQRELEEREEKLKKRPLLF----ERVAQKNARMAAE 569
+ G+E+ + + EK MRE + ++ E+EEK++ + ER+ +++ R+ +
Sbjct: 462 IRDQEEMWGQEKKMWRQEK--MREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREK 519
Query: 570 KHYSNTLKALGISDEFVSKKGQSGKVLEYFNNQETKSVTEDKESFNEEEKIEERENGEEN 629
+ K + +E + +E K+ ++K+++++EEK+ E E E
Sbjct: 520 EERMREQKKMWQQEEKM--------------REEKKTQEQEKKTWDQEEKMREEERMRER 565
Query: 630 YFIDTNSQDSYKEKDEANEESEEEKSVEE 658
++ +E++E +E EE+ +E
Sbjct: 566 EKKMREEEEMMREQEEKMQEQEEKMREQE 594
Score = 45.1 bits (105), Expect = 2e-04
Identities = 98/507 (19%), Positives = 207/507 (40%), Gaps = 76/507 (14%)
Query: 175 EEELPNLEKEYPRKNRMMTYAKELINNMWTDFCVEDYIRCKDTGFHAAEKRRKKRKEWVP 234
EEEL EK+ ++ M +E + E +R ++ EKR +++++ +
Sbjct: 240 EEELREQEKKIRKQEEKMWRQEERLREQ------EGKMREQEEKMRRQEKRLREQEKELR 293
Query: 235 TITVPEPFQMMIREQKKK----EESMKSKSDI--EMVHKALKKQEEDPEYKKKFRANPVP 288
Q +REQ+++ EE M + + E K +++E E +K+ R
Sbjct: 294 EQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQK 353
Query: 289 A---SVFLPLYHDLVKQKEERRRSLK------EKSKEALLASQKPFKFIAREEQKRAARE 339
+ + +++KEER R + EK +E ++ K EE R E
Sbjct: 354 MRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEE 413
Query: 340 K-QLRDFLKYKKKTNRFKARPIPRSTYGSTTNDKLKE-EELYRNLRTQLRAQEHLQNSSP 397
K Q ++ ++++ ++ + +P +K++E EE ++R QE +
Sbjct: 414 KMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEK 473
Query: 398 LPCRSACGCRNPRCPEQAVKL-KCKHKVRCPTPDFEDLPERY--QKHLSEHKSPKLLTVC 454
R + EQ ++ + + K+R D ER Q K ++
Sbjct: 474 KMWRQE------KMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQK 527
Query: 455 KPFDLHASPHASIKREKILADIEADEENLKETRWPYLSPRRKSPVRCAGVNPVPCNCNPP 514
K + ++E+ + + + +E K+T W R+
Sbjct: 528 KMW----------QQEEKMREEKKTQEQEKKT-WDQEEKMREEE---------------- 560
Query: 515 VPTVSSRGREQAVRKSEKERMREYQRELEEREEKLKKRPLLFERVAQKNARMAAEKHYSN 574
R RE+ +R+ E+E MRE + +++E+EEK++++ E++ ++ +M ++
Sbjct: 561 ----RMREREKKMRE-EEEMMREQEEKMQEQEEKMREQE---EKMWEQEEKMQEQE---- 608
Query: 575 TLKALGISDEFVSKKGQSGKVLEYFN---NQETKSVTEDKESFNEEEKIEERENGEENYF 631
+ + +E + ++ + K+ E QE K ++++ + +EEK+ E+E
Sbjct: 609 --EKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQE 666
Query: 632 IDTNSQDSYKEKDEANEESEEEKSVEE 658
Q+ + E + +EEK E+
Sbjct: 667 EKMQGQEEKMREQEEKMQGQEEKMREQ 693
Score = 41.2 bits (95), Expect = 0.003
Identities = 35/151 (23%), Positives = 70/151 (46%), Gaps = 12/151 (7%)
Query: 521 RGREQAVRKSEKERMREYQRELEEREEKLKKRPLLFERVAQKNARMAA-----EKHYSNT 575
R +E+ +R+ EK R+RE ++EL E+E++L+++ L E+ Q + EK
Sbjct: 272 REQEEKMRRQEK-RLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQE 330
Query: 576 LKALGISDEFVSKKGQSGKVLEYFNNQETKSVTEDK------ESFNEEEKIEERENGEEN 629
K + ++ Q + + +QE + +D+ E E+EK+ E+E +
Sbjct: 331 EKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQE 390
Query: 630 YFIDTNSQDSYKEKDEANEESEEEKSVEESH 660
+ +E++E E EE+ +E +
Sbjct: 391 EERIREREKKMREEEETMREQEEKMQKQEEN 421
Score = 37.0 bits (84), Expect = 0.058
Identities = 48/264 (18%), Positives = 114/264 (43%), Gaps = 23/264 (8%)
Query: 88 IHHSNEEYFKKVEELKAAHIETMAKLEKMYQDKLHLKEVQPVVIREDSLSDSSRSVSEKN 147
I E+ +++ E L+ + + EKM + + L+E + + ++ + + E+
Sbjct: 250 IRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQE 309
Query: 148 SYHPVSLMTSFSEPDLGQSSSLYVSSSEEELPNLEKEYPRKNRMMTYAKELINNMWTDFC 207
+ + + + + EE L EK+ + + M +E MW
Sbjct: 310 EQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEE---RMWEQ-- 364
Query: 208 VEDYIRCKDTGFHAAEKRRKKRKEWVPTITVPEPFQMMIREQKKKEESMKSKSDIEMVHK 267
++ +R K+ E+ R++ K W + E ++ RE+K +EE + E
Sbjct: 365 -DERLREKE------ERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEE---- 413
Query: 268 ALKKQEED--PEYKKKFRANPVPASVFLPLYHDLVKQKEERRRSLKEK--SKEALLASQK 323
++KQEE+ + +K+++ +P + ++++EE+ +EK +E + +K
Sbjct: 414 KMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEK 473
Query: 324 PF---KFIAREEQKRAAREKQLRD 344
+ + +E + +E+++RD
Sbjct: 474 KMWRQEKMREQEDQMWEQEEKMRD 497
Score = 33.1 bits (74), Expect = 0.84
Identities = 27/128 (21%), Positives = 63/128 (49%), Gaps = 17/128 (13%)
Query: 531 EKERMREYQRELEEREEKLKKRPLLFERVAQKNARMAAEKHYSNTLKALGISDEFVSKKG 590
++E+M+E + ++ E+EEK++++ E++ ++ +M ++ + ++ +G
Sbjct: 637 QEEKMQEQEEKMWEQEEKMREQE---EKMREQEEKMQGQEEK--------MREQEEKMQG 685
Query: 591 QSGKVLEY---FNNQETKSVTEDKESFNEEEKIEERENGEENYFIDTNSQDSYKEKDEAN 647
Q K+ E QE K ++++ + +EEK+ +E E + +D ++ E
Sbjct: 686 QEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREK---EERIRDQKEKMQERL 742
Query: 648 EESEEEKS 655
E EE S
Sbjct: 743 PEHEERCS 750
Score = 29.6 bits (65), Expect = 9.3
Identities = 66/363 (18%), Positives = 142/363 (39%), Gaps = 37/363 (10%)
Query: 93 EEYFKKVEELKAAHIETMAKLEKMYQDKLHLKEVQPVVIREDSLSDSSRSVSEKNSYHPV 152
EE +K EE E + +++ + K L E + + +E+ + + + ++
Sbjct: 412 EEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQ 471
Query: 153 SLMTSFSEPDLGQSSSLYVSSSEEELPNLE-KEYPRKNRMMTYAKELINNMWTDFCVEDY 211
E Q ++ EE++ + E K + ++ RM + L E+
Sbjct: 472 EKKMWRQEKMREQEDQMW--EQEEKMRDQEQKMWDQEERMWEQDERLREK-------EER 522
Query: 212 IRCKDTGFHAAEKRRKKRKE-------WVPTITVPEPFQMMIREQKKKEESMKSKSDIEM 264
+R + + EK R+++K W + E +M RE+K +EE EM
Sbjct: 523 MREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEE-------EM 575
Query: 265 VHKALKKQEEDPEYKKKFRANPVPASVFLPLYHDLVKQKEERRRSLKEKSKEALLASQKP 324
+ + +K +E E ++ + + + ++EE+ +E+ K Q+
Sbjct: 576 MREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDK-----MQEQ 630
Query: 325 FKFIAREEQKRAAREKQLRDFLKYKKKTNRFKARPIPRSTYGSTTNDKLKE-EELYRNLR 383
+ + +E+K +E+++ + + K + K R G +K++E EE +
Sbjct: 631 EEMMWEQEEKMQEQEEKMWE-QEEKMREQEEKMREQEEKMQGQ--EEKMREQEEKMQGQE 687
Query: 384 TQLRAQEHLQNSSPLPCRSACGCRNPRCPEQAVKLKCKHKVRCPTPDFEDLPERYQKHLS 443
++R QE + + Q K+ + ++R D E+ Q+ L
Sbjct: 688 EKMREQEEKMRGQ----EEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQERLP 743
Query: 444 EHK 446
EH+
Sbjct: 744 EHE 746
>gi|115529449 upstream binding transcription factor, RNA polymerase
I isoform b [Homo sapiens]
Length = 727
Score = 45.8 bits (107), Expect = 1e-04
Identities = 122/614 (19%), Positives = 234/614 (38%), Gaps = 112/614 (18%)
Query: 92 NEEYFKKVEELKAAHIETMAKLEKMYQDKL-HLKEVQPVVIREDSLSDSSRS-------- 142
+++Y + E+ K +I+ + ++ ++ L +E P +I+ SD
Sbjct: 147 SKKYKELPEKKKMKYIQDFQREKQEFERNLARFREDHPDLIQNAKKSDIPEKPKTPQQLW 206
Query: 143 -VSEKNSY---HPVSLMTSFSE--PDLGQSSSLYVSSS----EEELPNLEKEYPRK---N 189
EK Y P +M + + P+L S S+ E +L + P K N
Sbjct: 207 YTHEKKVYLKVRPDEIMRDYIQKHPELNISEEGITKSTLTKAERQLKDKFDGRPTKPPPN 266
Query: 190 RMMTYAKELINNMWTDFCVEDYIRCKDTGFHAAEKRR--------KKRKEWVPTI----- 236
Y EL+ NM E + C ++K + +K+K++ +
Sbjct: 267 SYSLYCAELMANMKDVPSTERMVLCSQQWKLLSQKEKDAYHKKCDQKKKDYEVELLRFLE 326
Query: 237 TVPEPFQMMIREQKKKEESMKSKSDIEMVHKALKKQEEDPEYKKKFRANPVPASVFLPLY 296
++PE Q + ++K K ++ K ++ + K K PV A
Sbjct: 327 SLPEEEQQRVLGEEKMLNINKKQATSPASKKPAQEGGKGGSEKPK---RPVSAMFIF--- 380
Query: 297 HDLVKQKEERRRSLKEKSKEALLASQKPFKFIAREEQKRAAREKQLRDFLKYKKKTNRFK 356
EE+RR L+E+ E L+ + + +AR + ++K KYK + K
Sbjct: 381 ------SEEKRRQLQEERPE--LSESELTRLLARMWNDLSEKKKA-----KYKAREAALK 427
Query: 357 ARPIPRSTYGSTTNDKLKEEELYRNLRTQLRAQEHLQNSSPLPCRSACGCRNPRCPEQAV 416
A+ + KL E + RA+E Q +S G R V
Sbjct: 428 AQSERKPGGEREERGKLPE--------SPKRAEEIWQ-------QSVIGDYLARFKNDRV 472
Query: 417 K-----------LKCKHKVRCPTPDFEDLPERYQKHLSEHKSPKLLT-VCKPFDLHASPH 464
K ++ K K+ ED +RY++ LSE ++P T K P
Sbjct: 473 KALKAMEMTWNNMEKKEKLMWIKKAAED-QKRYERELSEMRAPPAATNSSKKMKFQGEP- 530
Query: 465 ASIKREKILADIEADEENLKETRWPYLSPRRKSPVRCAGVNPVPCNCNPPVPTVSSRGRE 524
K+ + + +E L +L + + V R
Sbjct: 531 ---KKPPMNGYQKFSQELLSNGELNHLPLKERM--------------------VEIGSRW 567
Query: 525 QAVRKSEKERMREYQRELEEREEKLKKRPLLFERVAQKNARMAAEKHYSNTLKALGISDE 584
Q + +S+KE Y++ EE++++ K L+ + R A +++ SN K++ +
Sbjct: 568 QRISQSQKEH---YKKLAEEQQKQYKVHLDLWVKSLSPQDRAAYKEYISNKRKSM---TK 621
Query: 585 FVSKKGQSGKVLEYFNNQETKSVTEDKESFNEEEKIEERENGEENYFIDTNSQDSYKEKD 644
+S + ++ + ED++ +E+E+ E+ ENG+ + +S+ S +++
Sbjct: 622 LRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDES 681
Query: 645 EANEESEEEKSVEE 658
E +E+EE+ E+
Sbjct: 682 EDGDENEEDDEDED 695
>gi|115529451 upstream binding transcription factor, RNA polymerase
I isoform b [Homo sapiens]
Length = 727
Score = 45.8 bits (107), Expect = 1e-04
Identities = 122/614 (19%), Positives = 234/614 (38%), Gaps = 112/614 (18%)
Query: 92 NEEYFKKVEELKAAHIETMAKLEKMYQDKL-HLKEVQPVVIREDSLSDSSRS-------- 142
+++Y + E+ K +I+ + ++ ++ L +E P +I+ SD
Sbjct: 147 SKKYKELPEKKKMKYIQDFQREKQEFERNLARFREDHPDLIQNAKKSDIPEKPKTPQQLW 206
Query: 143 -VSEKNSY---HPVSLMTSFSE--PDLGQSSSLYVSSS----EEELPNLEKEYPRK---N 189
EK Y P +M + + P+L S S+ E +L + P K N
Sbjct: 207 YTHEKKVYLKVRPDEIMRDYIQKHPELNISEEGITKSTLTKAERQLKDKFDGRPTKPPPN 266
Query: 190 RMMTYAKELINNMWTDFCVEDYIRCKDTGFHAAEKRR--------KKRKEWVPTI----- 236
Y EL+ NM E + C ++K + +K+K++ +
Sbjct: 267 SYSLYCAELMANMKDVPSTERMVLCSQQWKLLSQKEKDAYHKKCDQKKKDYEVELLRFLE 326
Query: 237 TVPEPFQMMIREQKKKEESMKSKSDIEMVHKALKKQEEDPEYKKKFRANPVPASVFLPLY 296
++PE Q + ++K K ++ K ++ + K K PV A
Sbjct: 327 SLPEEEQQRVLGEEKMLNINKKQATSPASKKPAQEGGKGGSEKPK---RPVSAMFIF--- 380
Query: 297 HDLVKQKEERRRSLKEKSKEALLASQKPFKFIAREEQKRAAREKQLRDFLKYKKKTNRFK 356
EE+RR L+E+ E L+ + + +AR + ++K KYK + K
Sbjct: 381 ------SEEKRRQLQEERPE--LSESELTRLLARMWNDLSEKKKA-----KYKAREAALK 427
Query: 357 ARPIPRSTYGSTTNDKLKEEELYRNLRTQLRAQEHLQNSSPLPCRSACGCRNPRCPEQAV 416
A+ + KL E + RA+E Q +S G R V
Sbjct: 428 AQSERKPGGEREERGKLPE--------SPKRAEEIWQ-------QSVIGDYLARFKNDRV 472
Query: 417 K-----------LKCKHKVRCPTPDFEDLPERYQKHLSEHKSPKLLT-VCKPFDLHASPH 464
K ++ K K+ ED +RY++ LSE ++P T K P
Sbjct: 473 KALKAMEMTWNNMEKKEKLMWIKKAAED-QKRYERELSEMRAPPAATNSSKKMKFQGEP- 530
Query: 465 ASIKREKILADIEADEENLKETRWPYLSPRRKSPVRCAGVNPVPCNCNPPVPTVSSRGRE 524
K+ + + +E L +L + + V R
Sbjct: 531 ---KKPPMNGYQKFSQELLSNGELNHLPLKERM--------------------VEIGSRW 567
Query: 525 QAVRKSEKERMREYQRELEEREEKLKKRPLLFERVAQKNARMAAEKHYSNTLKALGISDE 584
Q + +S+KE Y++ EE++++ K L+ + R A +++ SN K++ +
Sbjct: 568 QRISQSQKEH---YKKLAEEQQKQYKVHLDLWVKSLSPQDRAAYKEYISNKRKSM---TK 621
Query: 585 FVSKKGQSGKVLEYFNNQETKSVTEDKESFNEEEKIEERENGEENYFIDTNSQDSYKEKD 644
+S + ++ + ED++ +E+E+ E+ ENG+ + +S+ S +++
Sbjct: 622 LRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDES 681
Query: 645 EANEESEEEKSVEE 658
E +E+EE+ E+
Sbjct: 682 EDGDENEEDDEDED 695
>gi|88759339 aster-associated protein [Homo sapiens]
Length = 647
Score = 45.4 bits (106), Expect = 2e-04
Identities = 39/142 (27%), Positives = 66/142 (46%), Gaps = 5/142 (3%)
Query: 223 EKRRKKRKEWVPTITVPEPFQMMIREQKKKEESMKSKSDIEMVHKALKKQEEDPEYKKKF 282
E++ KK+ E E Q + ++KK E +K K+ E ++ KKQ+E+ +K
Sbjct: 494 EEKNKKKTEEENAARKGEALQAFEKWKEKKMEYLKEKNRKEREYERAKKQKEEETVAEKK 553
Query: 283 RANPVPASVFLPLYHDLVKQKEERRRSLKEKSKEALLASQKPFK---FIAREEQKRAARE 339
+ N + KQKE+ + + EK KE L ++K K I E+ +E
Sbjct: 554 KDNLTAVEKWNEKKEAFFKQKEKEK--INEKRKEELKRAEKKDKDKQAINEYEKWLENKE 611
Query: 340 KQLRDFLKYKKKTNRFKARPIP 361
KQ R K KK+ + ++ +P
Sbjct: 612 KQERIERKQKKRHSFLESEALP 633
Score = 36.2 bits (82), Expect = 0.099
Identities = 44/183 (24%), Positives = 80/183 (43%), Gaps = 20/183 (10%)
Query: 165 QSSSLYVSSSEEELPNLE--KEYPRKNRMMTYAKELINNMWTDFCVEDYIRCKDTGFHAA 222
Q+ + EE L + E K K AK+ + E+ K A
Sbjct: 457 QNEQKKAAKREEALASFEAWKAMKEKEAKKIAAKKRLEEKNKKKTEEENAARKGEALQAF 516
Query: 223 EKRRKKRKEWVPTITVPEPFQMMIREQKKKEE-SMKSKSDIEMVHKALKKQEEDPEYKKK 281
EK ++K+ E++ E ++QK++E + K K ++ V K +K+E + K+K
Sbjct: 517 EKWKEKKMEYLKEKNRKEREYERAKKQKEEETVAEKKKDNLTAVEKWNEKKEAFFKQKEK 576
Query: 282 FRANPVPASVFLPLYHDLVKQKEE-RRRSLKEKSKEALLASQKPFKFIAREEQKRAAREK 340
+ N K+KEE +R K+K K+A+ +K + +E+Q+R R++
Sbjct: 577 EKINE--------------KRKEELKRAEKKDKDKQAINEYEKWLE--NKEKQERIERKQ 620
Query: 341 QLR 343
+ R
Sbjct: 621 KKR 623
Score = 33.9 bits (76), Expect = 0.49
Identities = 31/141 (21%), Positives = 61/141 (43%), Gaps = 20/141 (14%)
Query: 529 KSEKERMREYQRELEEREEKLKKRPLLFERVAQKNARMAAEKHYSNTLKALGISDEFVSK 588
+SE R++ Q++ +REE L ++ + +K A+ A K +E ++
Sbjct: 450 ESENLRIQNEQKKAAKREEALASFEA-WKAMKEKEAKKIAAKKRLEEKNKKKTEEENAAR 508
Query: 589 KGQSGKVLEYFNNQETKSVTEDKESFNEEEKIEERENGEENYFIDTNSQDSY-------- 640
KG++ L+ F + K + KE +E + E + +E + +D+
Sbjct: 509 KGEA---LQAFEKWKEKKMEYLKEKNRKEREYERAKKQKEEETVAEKKKDNLTAVEKWNE 565
Query: 641 --------KEKDEANEESEEE 653
KEK++ NE+ +EE
Sbjct: 566 KKEAFFKQKEKEKINEKRKEE 586
Score = 30.4 bits (67), Expect = 5.4
Identities = 38/144 (26%), Positives = 61/144 (42%), Gaps = 16/144 (11%)
Query: 524 EQAVRKSE--------KERMREYQREL--EEREEKLKKRPLLFERVAQKNA-RMAAEKHY 572
E A RK E KE+ EY +E +ERE + K+ E VA+K + A + +
Sbjct: 504 ENAARKGEALQAFEKWKEKKMEYLKEKNRKEREYERAKKQKEEETVAEKKKDNLTAVEKW 563
Query: 573 SNTLKALGISDEFVSKKGQSGKVLEYFNNQETKSVTEDKESFNEEEKIEERENGEENYFI 632
+ +A E K+ + K E E K +DK++ NE EK E + +E
Sbjct: 564 NEKKEAFFKQKE---KEKINEKRKEELKRAEKKD--KDKQAINEYEKWLENKEKQERIER 618
Query: 633 DTNSQDSYKEKDEANEESEEEKSV 656
+ S+ E + S ++V
Sbjct: 619 KQKKRHSFLESEALPPWSPPSRTV 642
>gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]
Length = 780
Score = 45.1 bits (105), Expect = 2e-04
Identities = 47/168 (27%), Positives = 77/168 (45%), Gaps = 40/168 (23%)
Query: 524 EQAVRKSEKER-MREYQRELEEREEKLKKRPLLFERVAQKNARMAAEKH-------YSNT 575
EQ RK E+ER MRE Q+E E++E+ ++ ER ++ AR H YS+
Sbjct: 167 EQLERKRERERKMREQQKEQREQKERERRAE---ERRKEREARREVSAHHRTMREDYSDK 223
Query: 576 LKA----------------LG-----ISDEFVSKKGQSGKVLEYFNNQETKSVTE----D 610
+KA LG + +E + ++ + + +++ S E +
Sbjct: 224 VKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAE 283
Query: 611 KESFNEEEKIEERENGEENYFIDTNSQDSYKEKDEANEESEEEKSVEE 658
S +EEE+ EE E EE + S++S +E++E EE EE S E
Sbjct: 284 SGSGSEEEEEEEEEEEEEG----STSEESEEEEEEEEEEEEETGSNSE 327
Score = 30.4 bits (67), Expect = 5.4
Identities = 26/138 (18%), Positives = 57/138 (41%), Gaps = 8/138 (5%)
Query: 529 KSEKERMREYQRELEEREEKLKKRPLLFERVAQKNARMAAEKHYSNTLKALGISDEFVSK 588
K EK R+ +L++ + +K A+ + E+ + G + E +
Sbjct: 251 KEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEE 310
Query: 589 KGQSGKVLEYFNNQETKSVTEDK-ESFNEEEKIEERENGEENYFI-------DTNSQDSY 640
+ + + E ++ +E E +EEE E+ E EN+ + D +S +S
Sbjct: 311 EEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESE 370
Query: 641 KEKDEANEESEEEKSVEE 658
+ ++E E + + ++ E
Sbjct: 371 EAEEEVGEGTPQSSALTE 388
>gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isoform
5 [Homo sapiens]
Length = 748
Score = 45.1 bits (105), Expect = 2e-04
Identities = 47/168 (27%), Positives = 77/168 (45%), Gaps = 40/168 (23%)
Query: 524 EQAVRKSEKER-MREYQRELEEREEKLKKRPLLFERVAQKNARMAAEKH-------YSNT 575
EQ RK E+ER MRE Q+E E++E+ ++ ER ++ AR H YS+
Sbjct: 135 EQLERKRERERKMREQQKEQREQKERERRAE---ERRKEREARREVSAHHRTMREDYSDK 191
Query: 576 LKA----------------LG-----ISDEFVSKKGQSGKVLEYFNNQETKSVTE----D 610
+KA LG + +E + ++ + + +++ S E +
Sbjct: 192 VKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAE 251
Query: 611 KESFNEEEKIEERENGEENYFIDTNSQDSYKEKDEANEESEEEKSVEE 658
S +EEE+ EE E EE + S++S +E++E EE EE S E
Sbjct: 252 SGSGSEEEEEEEEEEEEEG----STSEESEEEEEEEEEEEEETGSNSE 295
Score = 30.4 bits (67), Expect = 5.4
Identities = 26/138 (18%), Positives = 57/138 (41%), Gaps = 8/138 (5%)
Query: 529 KSEKERMREYQRELEEREEKLKKRPLLFERVAQKNARMAAEKHYSNTLKALGISDEFVSK 588
K EK R+ +L++ + +K A+ + E+ + G + E +
Sbjct: 219 KEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEE 278
Query: 589 KGQSGKVLEYFNNQETKSVTEDK-ESFNEEEKIEERENGEENYFI-------DTNSQDSY 640
+ + + E ++ +E E +EEE E+ E EN+ + D +S +S
Sbjct: 279 EEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESE 338
Query: 641 KEKDEANEESEEEKSVEE 658
+ ++E E + + ++ E
Sbjct: 339 EAEEEVGEGTPQSSALTE 356
Score = 30.0 bits (66), Expect = 7.1
Identities = 31/119 (26%), Positives = 52/119 (43%), Gaps = 11/119 (9%)
Query: 532 KERMREYQRELEEREEKLKKRPLLFERVAQKNARMAAEKHYSNTLKALGISDEFVSKKGQ 591
KE+ RE++R REE+ K R E QK MA E ++ + ++ K+ +
Sbjct: 91 KEKEREHERRKRHREEQDKARR---EWERQKRREMARE----HSRRERDRLEQLERKRER 143
Query: 592 SGKVLEYFNNQETKSVTEDKESFNEEEKIEERENGEENYFIDTNSQDSYKEKDEANEES 650
K+ E Q + E + EE+ +ERE E ++ Y +K +A+ S
Sbjct: 144 ERKMREQQKEQREQKERERR----AEERRKEREARREVSAHHRTMREDYSDKVKASHWS 198
>gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isoform
2 [Homo sapiens]
Length = 782
Score = 45.1 bits (105), Expect = 2e-04
Identities = 47/168 (27%), Positives = 77/168 (45%), Gaps = 40/168 (23%)
Query: 524 EQAVRKSEKER-MREYQRELEEREEKLKKRPLLFERVAQKNARMAAEKH-------YSNT 575
EQ RK E+ER MRE Q+E E++E+ ++ ER ++ AR H YS+
Sbjct: 169 EQLERKRERERKMREQQKEQREQKERERRAE---ERRKEREARREVSAHHRTMREDYSDK 225
Query: 576 LKA----------------LG-----ISDEFVSKKGQSGKVLEYFNNQETKSVTE----D 610
+KA LG + +E + ++ + + +++ S E +
Sbjct: 226 VKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAE 285
Query: 611 KESFNEEEKIEERENGEENYFIDTNSQDSYKEKDEANEESEEEKSVEE 658
S +EEE+ EE E EE + S++S +E++E EE EE S E
Sbjct: 286 SGSGSEEEEEEEEEEEEEG----STSEESEEEEEEEEEEEEETGSNSE 329
Score = 30.4 bits (67), Expect = 5.4
Identities = 26/138 (18%), Positives = 57/138 (41%), Gaps = 8/138 (5%)
Query: 529 KSEKERMREYQRELEEREEKLKKRPLLFERVAQKNARMAAEKHYSNTLKALGISDEFVSK 588
K EK R+ +L++ + +K A+ + E+ + G + E +
Sbjct: 253 KEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEE 312
Query: 589 KGQSGKVLEYFNNQETKSVTEDK-ESFNEEEKIEERENGEENYFI-------DTNSQDSY 640
+ + + E ++ +E E +EEE E+ E EN+ + D +S +S
Sbjct: 313 EEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESE 372
Query: 641 KEKDEANEESEEEKSVEE 658
+ ++E E + + ++ E
Sbjct: 373 EAEEEVGEGTPQSSALTE 390
Score = 30.0 bits (66), Expect = 7.1
Identities = 31/119 (26%), Positives = 52/119 (43%), Gaps = 11/119 (9%)
Query: 532 KERMREYQRELEEREEKLKKRPLLFERVAQKNARMAAEKHYSNTLKALGISDEFVSKKGQ 591
KE+ RE++R REE+ K R E QK MA E ++ + ++ K+ +
Sbjct: 125 KEKEREHERRKRHREEQDKARR---EWERQKRREMARE----HSRRERDRLEQLERKRER 177
Query: 592 SGKVLEYFNNQETKSVTEDKESFNEEEKIEERENGEENYFIDTNSQDSYKEKDEANEES 650
K+ E Q + E + EE+ +ERE E ++ Y +K +A+ S
Sbjct: 178 ERKMREQQKEQREQKERERR----AEERRKEREARREVSAHHRTMREDYSDKVKASHWS 232
>gi|29294649 dicer1 [Homo sapiens]
Length = 1922
Score = 44.7 bits (104), Expect = 3e-04
Identities = 28/109 (25%), Positives = 54/109 (49%), Gaps = 13/109 (11%)
Query: 535 MREYQRELEEREEKLKKRPLLFERVAQKNARMAAEKHYS-----------NTLKALGISD 583
+RE Q+ ++ +E+L ++ LLF + E+H+S +K L I
Sbjct: 326 VRELQKYIKHEQEELHRKFLLFTDTFLRKIHALCEEHFSPASLDLKFVTPKVIKLLEILR 385
Query: 584 EFVSKKGQSGKVLEYFNNQETKSVTE--DKESFNEEEKIEERENGEENY 630
++ + Q + +E++NN+ + D E +E+E+IEE+E E N+
Sbjct: 386 KYKPYERQQFESVEWYNNRNQDNYVSWSDSEDDDEDEEIEEKEKPETNF 434
>gi|29294651 dicer1 [Homo sapiens]
Length = 1922
Score = 44.7 bits (104), Expect = 3e-04
Identities = 28/109 (25%), Positives = 54/109 (49%), Gaps = 13/109 (11%)
Query: 535 MREYQRELEEREEKLKKRPLLFERVAQKNARMAAEKHYS-----------NTLKALGISD 583
+RE Q+ ++ +E+L ++ LLF + E+H+S +K L I
Sbjct: 326 VRELQKYIKHEQEELHRKFLLFTDTFLRKIHALCEEHFSPASLDLKFVTPKVIKLLEILR 385
Query: 584 EFVSKKGQSGKVLEYFNNQETKSVTE--DKESFNEEEKIEERENGEENY 630
++ + Q + +E++NN+ + D E +E+E+IEE+E E N+
Sbjct: 386 KYKPYERQQFESVEWYNNRNQDNYVSWSDSEDDDEDEEIEEKEKPETNF 434
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 44.7 bits (104), Expect = 3e-04
Identities = 80/411 (19%), Positives = 168/411 (40%), Gaps = 51/411 (12%)
Query: 222 AEKRRKKRKEWVPTITVPEPFQMMIREQKKKEESMKSKSDIEMVHKALKK-QEEDPEYKK 280
AEK+ ++RK+ + + +R+ K+KEE K D ++ +K +EE + K
Sbjct: 233 AEKKERERKK-------RDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEETVKSKV 285
Query: 281 KFRANPVPAS-------VFLPLYHDLVKQKEERRRSLKEKSKEALLASQKPFKFIAREEQ 333
+PAS ++ K+K+++++ EK ++ + P K + Q
Sbjct: 286 TVDTGVIPASEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQ 345
Query: 334 KRAAREKQLRDFLKYKKKTNRFKARPIPRSTYGSTTNDKLKEEELYRNLRTQLRAQEHLQ 393
+ A+ L++ + +K+ + + + ++L++E+ R + + +E L+
Sbjct: 346 EALAK---LKEEEERQKREEEERIKRLEELEAKRKEEERLEQEKRERKKQKEKERKERLK 402
Query: 394 NSSPLPCRSACGCRNPRCPEQAVKLKCKHKVRCPTPDFEDLPERYQKHLSEHKSPKLLTV 453
L +S R R +A LK P + LP++ + + E K K +
Sbjct: 403 KEGKLLTKSQ---REARARAEAT-LKLLQAQGVEVPSKDSLPKK--RPIYEDKKRKKI-- 454
Query: 454 CKPFDLHASPHASIKREKILADIEADEENL--KETRWPYLSPRRKSPVRCAGVNPVPCNC 511
P L + + + ++ A +E E+ + KE P + P + AG++
Sbjct: 455 --PQQLESKEVS--ESMELCAAVEVMEQGVPEKEETPPPVEPEEEEDTEDAGLDDWEAMA 510
Query: 512 NPPVPTVSSRGREQAVRKSEKERMREYQRELEEREEKLKKRPLLFERVAQKNARMAAEKH 571
+ T G + + E E + E EE +E+ ++ E + E+
Sbjct: 511 SDE-ETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEESEEEE---EEEGESEGSEGDEE- 565
Query: 572 YSNTLKALGISDEFVSKKGQSGKVLEYFNNQETKSVTEDKESFNEEEKIEE 622
DE VS + SGK L+ + +K ++ D E +++++ +E
Sbjct: 566 -----------DEKVSDEKDSGKTLD---KKPSKEMSSDSEYDSDDDRTKE 602
Score = 37.7 bits (86), Expect = 0.034
Identities = 47/180 (26%), Positives = 70/180 (38%), Gaps = 47/180 (26%)
Query: 521 RGREQAVRKSEKERMREYQREL-----EEREEKLKKRPLLFERVAQKNARMAAEKHYSNT 575
R E ++ E+ER+ + +RE +ER+E+LKK L + +Q+ AR AE T
Sbjct: 368 RLEELEAKRKEEERLEQEKRERKKQKEKERKERLKKEGKLLTK-SQREARARAEA----T 422
Query: 576 LKALGISDEFVSKKGQSGKVLEYFNNQETKSVTEDKESFNEEEKIE-------------- 621
LK L V K K + +++ K + + ES E +E
Sbjct: 423 LKLLQAQGVEVPSKDSLPKKRPIYEDKKRKKIPQQLESKEVSESMELCAAVEVMEQGVPE 482
Query: 622 ----------ERENGEENYFID---TNSQDSYKEKDEAN----------EESEEEKSVEE 658
E E E+ +D + D EK E N EE EEE+ EE
Sbjct: 483 KEETPPPVEPEEEEDTEDAGLDDWEAMASDEETEKVEGNKVHIEVKENPEEEEEEEEEEE 542
Score = 37.0 bits (84), Expect = 0.058
Identities = 38/158 (24%), Positives = 66/158 (41%), Gaps = 15/158 (9%)
Query: 512 NPPVPTVSSRGREQ---------AVRKSEK-ERMREYQRELEEREEKLK-KRPLLFERVA 560
N P P + S + A +K+EK ER R+ + E + + KLK K L +
Sbjct: 206 NKPGPNIESGNEDDDASFKIKTVAQKKAEKKERERKKRDEEKAKLRKLKEKEELETGKKD 265
Query: 561 QKNARMAAEKHYSNTLKALGISDEFV----SKKGQSGKVLEYFNNQETKSVTEDKESFNE 616
Q + + K T+K+ D V +K ++ E N + K + K+ +
Sbjct: 266 QSKQKESQRKFEEETVKSKVTVDTGVIPASEEKAETPTAAEDDNEGDKKKKDKKKKKGEK 325
Query: 617 EEKIEERENGEENYFIDTNSQDSYKEKDEANEESEEEK 654
EEK +E++ G + + K K+E + EE+
Sbjct: 326 EEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEE 363
Score = 34.7 bits (78), Expect = 0.29
Identities = 90/462 (19%), Positives = 167/462 (36%), Gaps = 94/462 (20%)
Query: 257 KSKSDIEMVHKALKKQEEDPEYKKKFRANPV---------PASVFLPLYHDLVKQKEERR 307
K+K + +K EED + KK + + FL K ++ +
Sbjct: 149 KAKGKAQKSNKKWDGSEEDEDNSKKIKERSRINSSGESGDESDEFLQSRKGQKKNQKNKP 208
Query: 308 RSLKEKSKEALLASQKPFKFIAREEQKRAAREKQLRDFLKYKKKTNRFKARPIPRSTYGS 367
E E AS K K +A+++ ++ RE++ RD + K K + K + +
Sbjct: 209 GPNIESGNEDDDASFK-IKTVAQKKAEKKERERKKRD--EEKAKLRKLKEK----EELET 261
Query: 368 TTNDKLKEEELYRNLRTQLRAQEHLQNSSPLPCRSACGCRNPRCPEQAVKLKCKHKVRCP 427
D+ K++E R + + ++ +P S P E + K K +
Sbjct: 262 GKKDQSKQKESQRKFEEETVKSKVTVDTGVIPA-SEEKAETPTAAEDDNEGDKKKKDKKK 320
Query: 428 TPDFEDLPERYQKHLSEHKSPKLLTVCKPFDLHASPHASIKREKILADIEADEENLKETR 487
E+ +K + K P TV + A +R+K +EE +K R
Sbjct: 321 KKG-----EKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQK-----REEEERIK--R 368
Query: 488 WPYLSPRRKSPVRCAGVNPVPCNCNPPVPTVSSRGREQAVRKSEKERMREY-------QR 540
L +RK R R R++ K KER+++ QR
Sbjct: 369 LEELEAKRKEEERLEQ---------------EKRERKKQKEKERKERLKKEGKLLTKSQR 413
Query: 541 ELEEREEKL------------------KKRPLLFERVAQKNARMAAEKHYSNTLK---AL 579
E R E KKRP+ ++ +K + K S +++ A+
Sbjct: 414 EARARAEATLKLLQAQGVEVPSKDSLPKKRPIYEDKKRKKIPQQLESKEVSESMELCAAV 473
Query: 580 GISDEFVSKKGQSGKVLEYFNNQETK--------SVTEDKESFN--------------EE 617
+ ++ V +K ++ +E ++T+ ++ D+E+ EE
Sbjct: 474 EVMEQGVPEKEETPPPVEPEEEEDTEDAGLDDWEAMASDEETEKVEGNKVHIEVKENPEE 533
Query: 618 EKIEERENGEENYFIDTNSQDSYKEKDEANEESEEEKSVEES 659
E+ EE E E+ + ++ E E +EE E+ ++S
Sbjct: 534 EEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDS 575
Score = 33.1 bits (74), Expect = 0.84
Identities = 95/586 (16%), Positives = 223/586 (38%), Gaps = 61/586 (10%)
Query: 97 KKVEELKAAHIETMAKLEKMYQDKLHLKEVQPVVIREDSLSDSSRSVSEKNSYHPVSLMT 156
K+ E K+ + K ++ + + LKE++ + + + +V+ K + + T
Sbjct: 33 KEQEPQKSKGKKKKEKKKQDFDEDDILKELEELSLEAQGIKADRETVAVKPTENNEEEFT 92
Query: 157 SFSEPDLGQSSSLYVSSSEEELPNLEKEYPRKNRMMTYAKELINNMWTDFCVEDYIRCKD 216
S + GQ S + + LE + + + E+ + D +D+ +
Sbjct: 93 SKDKKKKGQKGKKQ-SFDDNDSEELEDKDSKSKKTAKPKVEMYSGSDDD---DDFNKLPK 148
Query: 217 TGFHAAEKRRKKRKEWVPTITVPEPFQMMIREQKKKEESMKSKSDIEMVHKALKKQEED- 275
A K +K K+W + E I+E+ + S +S + + ++ K Q+++
Sbjct: 149 K---AKGKAQKSNKKWDGS-EEDEDNSKKIKERSRINSSGESGDESDEFLQSRKGQKKNQ 204
Query: 276 -----PEYKKKFRANPVPASVFLPLYHDLVKQKEERRRSLKEKSKEALLASQKPFKFIAR 330
P + + + K++ ER++ +EK+K L ++ + +
Sbjct: 205 KNKPGPNIESGNEDDDASFKIKTVAQKKAEKKERERKKRDEEKAKLRKLKEKEELETGKK 264
Query: 331 EEQKRAAREKQLRDFLKYKKKTNRFKARPI-------PRSTYGSTTNDKLKEEELYRNLR 383
++ K+ +++ + K T P P + DK K+++ +
Sbjct: 265 DQSKQKESQRKFEEETVKSKVTVDTGVIPASEEKAETPTAAEDDNEGDKKKKDKKKKKGE 324
Query: 384 TQLRAQEHLQNSSPLPCRSACGCRNPRCPEQAVKLKCKHKVRCPTPDFEDLPERYQKHLS 443
+ + +E + S ++ Q K K + + E+ +R ++ +
Sbjct: 325 KEEKEKEKKKGPSKATVKAM----------QEALAKLKEEEERQKREEEERIKRLEELEA 374
Query: 444 EHKSPKLLTVCKPFDLHASPHASIKREKILADIEADEENLKETRWPYLSPRRKSPVRCAG 503
+ K + L KRE+ + +E LK+ +R++ R
Sbjct: 375 KRKEEERLE-------------QEKRERKKQKEKERKERLKKEGKLLTKSQREARARAEA 421
Query: 504 VNPVPCNCNPPVPTVSSRGREQAVRKSEKERMREYQRELEEREEKLK---KRPLLFERVA 560
+ VP+ S +++ + + +K + Q E +E E ++ ++ + V
Sbjct: 422 TLKLLQAQGVEVPSKDSLPKKRPIYEDKKRKKIPQQLESKEVSESMELCAAVEVMEQGVP 481
Query: 561 QKNARMA-AEKHYSNTLKALGISD------EFVSKKGQSGKV-LEYFNNQETKSVTEDKE 612
+K E + G+ D + ++K + KV +E N E + E++E
Sbjct: 482 EKEETPPPVEPEEEEDTEDAGLDDWEAMASDEETEKVEGNKVHIEVKENPEEEEEEEEEE 541
Query: 613 SFNEEEKIEERENGEENYFIDTNSQDSYKEKDEANEESEEEKSVEE 658
+EE + EE E GE + + +E ++ ++E + K++++
Sbjct: 542 EEDEESEEEEEEEGE------SEGSEGDEEDEKVSDEKDSGKTLDK 581
>gi|100816397 MYST histone acetyltransferase (monocytic leukemia) 4
[Homo sapiens]
Length = 2073
Score = 44.3 bits (103), Expect = 4e-04
Identities = 39/156 (25%), Positives = 68/156 (43%), Gaps = 24/156 (15%)
Query: 523 REQAVRKSEKERMREYQRELEEREEKLKKRPLLFERVAQKNARMAAEKHYSNTLKALGI- 581
R + + S E+++ R E + L+ P+L A AEK ++
Sbjct: 959 RREKLILSHMEKLKTCSRANELDPDSLRWTPILISNAAVSEEEREAEKEAERLMEQASCW 1018
Query: 582 ---SDEFVSKKGQS----GKVL---EYFNNQETKSVTED--------KESFNEEEKIEER 623
E +S + S KV +Y ++ E++ VT + KES EEE+ E+
Sbjct: 1019 EKEEQEILSTRANSRQSPAKVQSKNKYLHSPESRPVTGERGQLLELSKESSEEEEEEEDE 1078
Query: 624 ENGEENYFIDTNSQDSYKEKDEANEESEEEKSVEES 659
E EE ++ +E++E EE EEE++++ S
Sbjct: 1079 EEEEEE-----EEEEEDEEEEEEEEEEEEEENIQSS 1109
Score = 33.1 bits (74), Expect = 0.84
Identities = 44/191 (23%), Positives = 66/191 (34%), Gaps = 39/191 (20%)
Query: 505 NPVPCNCNPPVPTVSSRG----REQAVRKS--------------EKERMREYQRELEERE 546
NP P C P + RG R+ RK+ E + + + E E
Sbjct: 1238 NPEPLKCKQVWPKGTKRGLSKWRQNKERKTGFKLNLYTPPETPMEPDEQVTVEEQKETSE 1297
Query: 547 EKLKKRPLLFERVAQKNARMAAEKHYSNTLKALGISDEFVSKKGQSGKVLE--YFNNQET 604
K P+ E ++ + + + VS G+ E +E
Sbjct: 1298 GKTSPSPIRIEEEVKETGEALLPQEENRREETCAP----VSPNTSPGEKPEDDLIKPEEE 1353
Query: 605 KSVTEDKESFNEEEKIEERENG--------------EENYFIDTNSQDSYKEKD-EANEE 649
+ E++E EEE+ EE E G +E I T +DS + D E EE
Sbjct: 1354 EEEEEEEEEEEEEEEGEEEEGGGNVEKDPDGAKSQEKEEPEISTEKEDSARLDDHEEEEE 1413
Query: 650 SEEEKSVEESH 660
+EE S E H
Sbjct: 1414 EDEEPSHNEDH 1424
Score = 29.6 bits (65), Expect = 9.3
Identities = 36/175 (20%), Positives = 68/175 (38%), Gaps = 20/175 (11%)
Query: 480 EENLKETRWPYL-SPRRKSPVRCAGVNPVPCNCNPPVPTVSSRGREQAVRKSEKERMREY 538
EE +KET L + CA V+P P + E+ + E+E E
Sbjct: 1308 EEEVKETGEALLPQEENRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEE 1367
Query: 539 QRELEEREEKLKKRPLLFERVAQKNARMAAEKHYSNTLKALGISDEFVSKKGQSGKVLEY 598
+ E EE ++K P + ++ ++ EK S L D+ ++ + E
Sbjct: 1368 EGEEEEGGGNVEKDPDGAKSQEKEEPEISTEKEDSARL------DDHEEEEEED----EE 1417
Query: 599 FNNQETKSVTEDKESFNEEEKIEERENGEENY---------FIDTNSQDSYKEKD 644
++ E ++ +S E ++E+ E E++ F+D N Q + +
Sbjct: 1418 PSHNEDHDADDEDDSHMESAEVEKEELPRESFKEVLENQETFLDLNVQPGHSNPE 1472
>gi|146260271 hypothetical protein LOC129881 [Homo sapiens]
Length = 552
Score = 44.3 bits (103), Expect = 4e-04
Identities = 34/163 (20%), Positives = 74/163 (45%), Gaps = 8/163 (4%)
Query: 194 YAKELINNMWTDFCVEDYIRCKDTGFHAAEKRRKKRKEWVPTI--TVPEPFQMMIREQKK 251
Y E + N + + ++ +D + + K K+W + + + F+ EQ+K
Sbjct: 147 YQTERVKNFHSGLLLSRVMKERDAQIEFRKSKIKSDKKWEEQLKLNIEKAFK---EEQEK 203
Query: 252 KEESMKSKSDIEMVH-KALKKQEEDPEYKKKFRANPVPASVFLPLYHDLVKQK--EERRR 308
E+ + + + H K +K+ EE+ E +KK+ +++ +K E++R
Sbjct: 204 AEKRHRERVALAKDHLKQIKEHEEEEERRKKYEEKDAEEIKRQNALYEIEMRKKLEKKRE 263
Query: 309 SLKEKSKEALLASQKPFKFIAREEQKRAAREKQLRDFLKYKKK 351
+ E + L Q A E+Q++ ++++R F+K KK+
Sbjct: 264 EMHESRRRFLEHMQDKHIIKAVEQQQQEEEDEKMRKFIKAKKR 306
Score = 38.1 bits (87), Expect = 0.026
Identities = 60/275 (21%), Positives = 98/275 (35%), Gaps = 57/275 (20%)
Query: 89 HHSNEEYFKKVEELKAAHIETMAKLEKMYQDKLHLKEVQPVVIREDSLSDSSRSVSEKNS 148
H EE KK EE A I+ L ++ K K+ RE+ R +
Sbjct: 225 HEEEEERRKKYEEKDAEEIKRQNALYEIEMRKKLEKK------REEMHESRRRFLEHMQD 278
Query: 149 YHPVSLMTSFSEPDLGQSSSLYVSSSEEELPNLEKEYPRKNRMMTYAKELINNMWTDFCV 208
H + + EEE + K K R++ KE
Sbjct: 279 KHIIKAVEQ--------------QQQEEEDEKMRKFIKAKKRLIQMGKE----------- 313
Query: 209 EDYIRCKDTGFHAAEKRRKKRKEWVPTITVPEPFQMMIREQKKKEESMKSKSDIEMVHKA 268
K+ H ++R++R F + ++K E M DI
Sbjct: 314 ------KEAETHRLMEKRRERIH---------NFLSELLKEKLDNEDMIIARDIAEAEAE 358
Query: 269 LKKQEEDPEYKKKFRANPVPASVFLPLYHDLV-KQKEERRRSLKEKSKEALLASQKPFK- 326
+K+E + + K K + Y +V K KEE R K ++KE LLA K +
Sbjct: 359 WEKREREKDEKNKAELKTIAE------YRAIVMKNKEEEERQRKIEAKEQLLAVMKADQI 412
Query: 327 FIAREEQKRAAREK---QLRDFLKYKKKTNRFKAR 358
F E++K+ +K +++D + N+F A+
Sbjct: 413 FWEHEKEKKCKADKEHQEVQDAHIQQMAKNKFNAK 447
Score = 30.0 bits (66), Expect = 7.1
Identities = 33/135 (24%), Positives = 51/135 (37%), Gaps = 22/135 (16%)
Query: 524 EQAVRKSEKERMREYQRELEEREEKLKKRPLLFERVAQKNARMAAEKHYSNTLKALGISD 583
+Q RK E ++YQ ER + LL + +++A++
Sbjct: 130 KQGKRKKAIENAKQYQFYQTERVKNFHSGLLLSRVMKERDAQI----------------- 172
Query: 584 EFVSKKGQSGKVLEYFNNQETKSVTEDKESFNEEEKIEERENGEENYFIDTNSQDSYKEK 643
EF K +S K E E + +K E+EK E+R D Q E+
Sbjct: 173 EFRKSKIKSDKKWE-----EQLKLNIEKAFKEEQEKAEKRHRERVALAKDHLKQIKEHEE 227
Query: 644 DEANEESEEEKSVEE 658
+E + EEK EE
Sbjct: 228 EEERRKKYEEKDAEE 242
>gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo
sapiens]
Length = 1116
Score = 43.9 bits (102), Expect = 5e-04
Identities = 41/156 (26%), Positives = 76/156 (48%), Gaps = 22/156 (14%)
Query: 243 QMMIREQKKKEESMKSKSDIEMVHKALKKQEEDPEYKKKFRANPVPASVFLPLYHDLVKQ 302
+ +++Q KK ++K K +E KK + E ++ N +S L D +++
Sbjct: 783 ERQVKDQNKKVANLKHKEQVEK-----KKSAQMLEEARRREDNLNDSSQQL---QDSLRK 834
Query: 303 KEERRRSLKEKSKEALLASQKPFKFIAREEQKRAAREKQLRDFL----KYKKKTNRFKAR 358
K++R L+E +E++ + + +A+EE R EKQ+ + L K K++ KA+
Sbjct: 835 KDDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEELLMAMEKVKQELESMKAK 894
Query: 359 PIPRSTYGSTTNDKLKEEELY-RNLRTQLRAQEHLQ 393
S+T L E+E + NLR + R +HL+
Sbjct: 895 L-------SSTQQSLAEKETHLTNLRAERR--KHLE 921
Score = 32.3 bits (72), Expect = 1.4
Identities = 32/154 (20%), Positives = 68/154 (44%), Gaps = 19/154 (12%)
Query: 249 QKKKEESMKSKSDIEMVHKALKKQEEDPEYKKKFRANPVPASVFLPLYHDLVKQKEERRR 308
++KKEE +K +S ++ H+A + PE + + L ++ + K+E +
Sbjct: 704 EQKKEECLKMESQLKKAHEAALEARASPEMSDRIQ----------HLEREITRYKDESSK 753
Query: 309 SLKEKSKEALLASQKPFKFIAREEQKRAAR-EKQLRD------FLKYKKKTNRFKARPIP 361
+ E + LL K + ++ K+ A E+Q++D LK+K++ + K+ +
Sbjct: 754 AQAEVDR--LLEILKEVENEKNDKDKKIAELERQVKDQNKKVANLKHKEQVEKKKSAQML 811
Query: 362 RSTYGSTTNDKLKEEELYRNLRTQLRAQEHLQNS 395
N ++L +LR + E L+ +
Sbjct: 812 EEARRREDNLNDSSQQLQDSLRKKDDRIEELEEA 845
Score = 31.6 bits (70), Expect = 2.4
Identities = 72/386 (18%), Positives = 150/386 (38%), Gaps = 47/386 (12%)
Query: 300 VKQKEERRRSLKEKSKEALLASQKPFKFIAREEQKRAAREKQLRDFLKYKKKTNRFKARP 359
++ KE++ SLKE+ K + + E+ A +E+ + + + + R K
Sbjct: 587 LRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQEE 646
Query: 360 IPRSTYGSTTND-----KLKEEELYRNLRTQLRAQEHLQN--SSPLPCRS-------ACG 405
I Y D L + +L + L +EH + SS L S A
Sbjct: 647 I--DNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLASSGLKKDSRLKTLEIALE 704
Query: 406 CRNPRCPEQAVKLKCKHKVRC---PTPDFEDLPERYQKHLSEHKS---------PKLLTV 453
+ C + +LK H+ +P+ D + ++ ++ +K +LL +
Sbjct: 705 QKKEECLKMESQLKKAHEAALEARASPEMSDRIQHLEREITRYKDESSKAQAEVDRLLEI 764
Query: 454 CKPFDLHASPHASIKREKILADIE--ADEENLKETRWPYLS--PRRKSPVRCAGVNPVPC 509
K + + ++K +A++E ++N K + ++KS
Sbjct: 765 LKEVE-----NEKNDKDKKIAELERQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRRED 819
Query: 510 NCNPPVPTVSSRGREQAVRKSEKERMREYQRELEEREEKLKKRPLLFERVAQKNARMAAE 569
N N SS+ + ++RK + +R+ E + L E + +R ++ + +++AR AE
Sbjct: 820 NLND-----SSQQLQDSLRKKD-DRIEELEEALRESVQITAEREMVLAQ--EESARTNAE 871
Query: 570 KHYSNTLKAL-GISDEFVSKKGQSGKVLEYFNNQETKSVTEDKESFNE-EEKIEERENGE 627
K L A+ + E S K + + +ET E EE +E ++
Sbjct: 872 KQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQEAL 931
Query: 628 ENYFIDTNSQDSYKEKDEANEESEEE 653
+ ++ + E + ++++EE
Sbjct: 932 LAAISEKDANIALLELSSSKKKTQEE 957
>gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens]
Length = 1088
Score = 43.9 bits (102), Expect = 5e-04
Identities = 41/156 (26%), Positives = 76/156 (48%), Gaps = 22/156 (14%)
Query: 243 QMMIREQKKKEESMKSKSDIEMVHKALKKQEEDPEYKKKFRANPVPASVFLPLYHDLVKQ 302
+ +++Q KK ++K K +E KK + E ++ N +S L D +++
Sbjct: 755 ERQVKDQNKKVANLKHKEQVEK-----KKSAQMLEEARRREDNLNDSSQQL---QDSLRK 806
Query: 303 KEERRRSLKEKSKEALLASQKPFKFIAREEQKRAAREKQLRDFL----KYKKKTNRFKAR 358
K++R L+E +E++ + + +A+EE R EKQ+ + L K K++ KA+
Sbjct: 807 KDDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEELLMAMEKVKQELESMKAK 866
Query: 359 PIPRSTYGSTTNDKLKEEELY-RNLRTQLRAQEHLQ 393
S+T L E+E + NLR + R +HL+
Sbjct: 867 L-------SSTQQSLAEKETHLTNLRAERR--KHLE 893
Score = 33.5 bits (75), Expect = 0.64
Identities = 116/614 (18%), Positives = 235/614 (38%), Gaps = 75/614 (12%)
Query: 88 IHHSNEEYFKKVEELKAAHIETMAKLEKMYQDKLHLKEVQPVVIREDS-LSDSSRSVSEK 146
+HH +K +E E + E D K +Q V+ +DS +S R + +
Sbjct: 343 VHHLESLLEQKEKENSMLREEMHRRFENA-PDSAKTKALQTVIEMKDSKISSMERGLRDL 401
Query: 147 NSYHPV-----SLMTSFSEPDLGQSSSLYVSSSE---EELPNLEKEYPRKNRMMTYAK-- 196
+ +L T E ++ Q +Y S S+ ++ +++E RK+ + +
Sbjct: 402 EEEIQMLKSNGALSTEEREEEMKQME-VYRSHSKFMKNKIGQVKQELSRKDTELLALQTK 460
Query: 197 -ELINNMWTDFCVEDYIRCKDTGFHAAEKRRKKRKEWVPTITVPEPFQMMIR-EQKKKEE 254
E + N ++D + +I A E+R I E + +R E+K+
Sbjct: 461 LETLTNQFSDS--KQHIEVLKESLTAKEQRA--------AILQTEVDALRLRLEEKETML 510
Query: 255 SMKSKSDIEMVHKALKKQEEDPEYKKKFRANPVPASVFLPLYHDLVKQ---KEERRRSLK 311
+ K+K +M + + E + K +V +L +Q KE++ SLK
Sbjct: 511 NKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLK 570
Query: 312 EKSKEALLASQKPFKFIAREEQKRAAREKQLRDFLKYKKKTNRFKARPIPRSTYGSTTND 371
E+ K + + E+ A +E+ + + + + R K I Y D
Sbjct: 571 ERVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQEEI--DNYKKDLKD 628
Query: 372 -----KLKEEELYRNLRTQLRAQEHLQN--SSPLPCRS-------ACGCRNPRCPEQAVK 417
L + +L + L +EH + SS L S A + C + +
Sbjct: 629 LKEKVSLLQGDLSEKEASLLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQ 688
Query: 418 LKCKHKVRC---PTPDFEDLPERYQKHLSEHKS---------PKLLTVCKPFDLHASPHA 465
LK H+ +P+ D + ++ ++ +K +LL + K + +
Sbjct: 689 LKKAHEAALEARASPEMSDRIQHLEREITRYKDESSKAQAEVDRLLEILKEVE-----NE 743
Query: 466 SIKREKILADIE--ADEENLKETRWPYLS--PRRKSPVRCAGVNPVPCNCNPPVPTVSSR 521
++K +A++E ++N K + ++KS N N SS+
Sbjct: 744 KNDKDKKIAELERQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLND-----SSQ 798
Query: 522 GREQAVRKSEKERMREYQRELEEREEKLKKRPLLFERVAQKNARMAAEKHYSNTLKAL-G 580
+ ++RK + +R+ E + L E + +R ++ + +++AR AEK L A+
Sbjct: 799 QLQDSLRKKD-DRIEELEEALRESVQITAEREMVLAQ--EESARTNAEKQVEELLMAMEK 855
Query: 581 ISDEFVSKKGQSGKVLEYFNNQETKSVTEDKESFNE-EEKIEERENGEENYFIDTNSQDS 639
+ E S K + + +ET E EE +E ++ + ++ +
Sbjct: 856 VKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAISEKDANIA 915
Query: 640 YKEKDEANEESEEE 653
E + ++++EE
Sbjct: 916 LLELSSSKKKTQEE 929
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 43.5 bits (101), Expect = 6e-04
Identities = 30/128 (23%), Positives = 64/128 (50%), Gaps = 5/128 (3%)
Query: 531 EKERMREYQRELEEREEKLKKRPLLFERVAQKNARMAAEKHYSNTLKALGISDEFVSKKG 590
E+E + + + + ++ K+ E+ + + + +E+H+S +++L DE ++
Sbjct: 2185 EEEEVIPFLKRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESL--LDELEKQES 2242
Query: 591 QSGKVLEYFNNQETKSVTEDKESFNEEEKIEERENGEENYFIDTNSQDSYKEKDEANEES 650
S + E +E + E++E EEE+ +E E GEE + K+K++ EE
Sbjct: 2243 LSSEEEEEREEEEER---EEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEV 2299
Query: 651 EEEKSVEE 658
+E++ V E
Sbjct: 2300 QEKEEVFE 2307
Score = 33.9 bits (76), Expect = 0.49
Identities = 26/106 (24%), Positives = 50/106 (47%), Gaps = 4/106 (3%)
Query: 523 REQAVRKSEKERMREYQRELEEREEKLKKRPLLFERVAQKNARMAAEKHYSNTLKALGIS 582
RE+ + E+E E Q E EE E+K KK+ E V +K ++ + + +S
Sbjct: 2263 REEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLS 2322
Query: 583 DEFVSKKGQSGKVLEYFNNQETKSVTEDKESFNEEEKIEERENGEE 628
DE ++ +S + E + + K + + ++ F +E+ + G E
Sbjct: 2323 DE--EEEEESCSLEEEVDRE--KEILKKEKQFKLQEQRRKSLRGRE 2364
Score = 32.0 bits (71), Expect = 1.9
Identities = 33/129 (25%), Positives = 53/129 (41%), Gaps = 19/129 (14%)
Query: 523 REQAVRKSEKERMREYQRELEEREEKLKKRPLLFERVAQKNARMAAEKHYSNTLKALGIS 582
+E + E+ER E +RE EE E+ ++R K EK
Sbjct: 2240 QESLSSEEEEEREEEEEREEEEVREEEEER---------KEEEEGEEKQVEK-------E 2283
Query: 583 DEFVSKKGQSGKVLEYFNNQETKSVTEDKESFNEEEKIEERENGEENYFIDTNSQDSYKE 642
+E KK + K E QE + V E+KE EE+ E + EE + ++ +E
Sbjct: 2284 EEEKKKKKKEKKKEEV---QEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDRE 2340
Query: 643 KDEANEESE 651
K+ +E +
Sbjct: 2341 KEILKKEKQ 2349
Score = 31.6 bits (70), Expect = 2.4
Identities = 32/151 (21%), Positives = 67/151 (44%), Gaps = 24/151 (15%)
Query: 521 RGREQAVRKSEKERMREYQRELEEREEKLKKRPLLFERVAQKNARMA-AEKHYSNTLKAL 579
R +E+ E+E++ + +R+L + E KL + + ++ Q + MA AE ++ + L
Sbjct: 1588 RAQEERKLAQEEEKLAQEERQLAQEERKLAQ---AYVKITQDDREMAQAEGKFAQKEETL 1644
Query: 580 GISDEFVSKKGQSGKVLEYFNNQETKSVTEDKESFNEE------------EKIEERENGE 627
E +S++ + ++ + V ++E ++ +K+EE E
Sbjct: 1645 AQRGEKLSQEAEKLAQKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVEELPQRE 1704
Query: 628 ENYFIDTNSQDSYKEKDEANEESEEEKSVEE 658
+N ++EK+ A E E E +EE
Sbjct: 1705 QNL--------DWQEKELAQELEELEWDMEE 1727
Score = 31.6 bits (70), Expect = 2.4
Identities = 21/113 (18%), Positives = 53/113 (46%), Gaps = 23/113 (20%)
Query: 248 EQKKKEESMKSKSDIEMVHKALKKQEEDPEYKKKFRANPVPASVFLPLYHDLVKQKEERR 307
E++++EE + + ++ + K++EE E + K++EE++
Sbjct: 2248 EEEREEEEEREEEEVREEEEERKEEEEGEE-------------------KQVEKEEEEKK 2288
Query: 308 RSLKEKSKEALLASQKPF----KFIAREEQKRAAREKQLRDFLKYKKKTNRFK 356
+ KEK KE + ++ F + ++ EE + + E++ + +++ +R K
Sbjct: 2289 KKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDREK 2341
Score = 30.8 bits (68), Expect = 4.2
Identities = 33/138 (23%), Positives = 61/138 (44%), Gaps = 14/138 (10%)
Query: 528 RKSEKERMREYQRELEEREEKLKKRPLLFERVAQKNARMAAEKHYSNTLKALGISDEFVS 587
RKS K E+++ L + EEKL + E+++ + + +K LK + +
Sbjct: 1475 RKSWKAWKEEWEKRLLQEEEKLHQAG---EKLSPEEEMLQEDK----KLKWEEWKQVWEN 1527
Query: 588 KKGQSGKVLEYFNNQET---KSVTEDKESFNEEEKIEERENGEENYFIDTNSQDSYKEKD 644
K +Y + +E + V+ + E ++ E+R EE+ + + + + EK
Sbjct: 1528 MLSSKSKEQQYKDEEEVTLEEEVSREGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKK 1587
Query: 645 EANEE----SEEEKSVEE 658
A EE EEEK +E
Sbjct: 1588 RAQEERKLAQEEEKLAQE 1605
Score = 30.4 bits (67), Expect = 5.4
Identities = 22/109 (20%), Positives = 50/109 (45%), Gaps = 16/109 (14%)
Query: 248 EQKKKEESMKSKSDIEMVHKALKKQEEDPEYKKKFRANPVPASVFLPLYHDLVKQKEERR 307
E++ +EE + K + E K ++K+EE+ + KKK + K++ + +
Sbjct: 2259 EEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKK----------------EKKKEEVQEK 2302
Query: 308 RSLKEKSKEALLASQKPFKFIAREEQKRAAREKQLRDFLKYKKKTNRFK 356
+ E+ +E + + EE++ + E+++ + KK +FK
Sbjct: 2303 EEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDREKEILKKEKQFK 2351
Score = 29.6 bits (65), Expect = 9.3
Identities = 19/98 (19%), Positives = 53/98 (54%), Gaps = 12/98 (12%)
Query: 523 REQAVRKSEKERMREYQRELEEREEKLKKRPLLFERVAQKNARMAAEK-HYSNTLKALGI 581
+E+ + EKE++ +++ ++ E EE+L ++ E++ +K ++A ++ + N+++ L
Sbjct: 1772 QEEELLIQEKEKLAQHKEKMPEEEERLGRKR---EQLIEKKMKLAQKRERWINSMEELTK 1828
Query: 582 SDEFVSKKGQSGKVLEYFNNQETKSVTEDKESFNEEEK 619
+ + +K QE K++ ++KE + ++
Sbjct: 1829 NKMILYQKKNLA--------QEKKNLAQEKEKLAQRKE 1858
>gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform
9 [Homo sapiens]
Length = 771
Score = 43.5 bits (101), Expect = 6e-04
Identities = 49/168 (29%), Positives = 78/168 (46%), Gaps = 40/168 (23%)
Query: 524 EQAVRKSEKER-MREYQRELEEREEKLKKRPLLFERVAQKNARMAAEKH-------YSNT 575
EQ RK E+ER MRE Q+E +RE+K ++R ER ++ AR H YS+
Sbjct: 158 EQLERKRERERKMREQQKE--QREQKERER-RAEERRKEREARREVSAHHRTMREDYSDK 214
Query: 576 LKA----------------LG-----ISDEFVSKKGQSGKVLEYFNNQETKSVTE----D 610
+KA LG + +E + ++ + + +++ S E +
Sbjct: 215 VKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAE 274
Query: 611 KESFNEEEKIEERENGEENYFIDTNSQDSYKEKDEANEESEEEKSVEE 658
S +EEE+ EE E EE + S++S +E++E EE EE S E
Sbjct: 275 SGSGSEEEEEEEEEEEEEG----STSEESEEEEEEEEEEEEETGSNSE 318
Score = 31.2 bits (69), Expect = 3.2
Identities = 69/366 (18%), Positives = 129/366 (35%), Gaps = 88/366 (24%)
Query: 301 KQKEERRRSLKEKSKEALLASQKPFKFIAREEQKRAAREKQLRDFLKYKKKTNRFKARPI 360
K+K R+ K K K+ +K E +R R ++ +D K +++ R K R +
Sbjct: 94 KEKVHHRKDEKRKEKKHARVKEK------EREHERRKRHREEQD--KARREWERQKRREM 145
Query: 361 PRSTYGSTTNDKLKEEELYRNLRTQLRAQEHLQNSSPLPCRSACGCRNPRCPEQAVKLKC 420
R + D+L++ E R ++R Q+ Q R A R E+ + +
Sbjct: 146 ARE-HSRRERDRLEQLERKRERERKMREQQKEQREQKERERRA----EERRKEREARREV 200
Query: 421 KHKVRCPTPDFEDLPERYQKHLSEHKSPKLLTVCKPFDLHASPHASIKREKILA-DIEAD 479
R D+ D + S + P+ + F+L +K EK+ D+ +D
Sbjct: 201 SAHHRTMREDYSDKVKASHWSRSPPRPPR-----ERFEL-GDGRKPVKEEKMEERDLLSD 254
Query: 480 EENLKETRWPYLSPRRKSPVRCAGVNPVPCNCNPPVPTVSSRGREQAVRKSEKERMREYQ 539
+++ + S R+ S + S E+ + E+E
Sbjct: 255 LQDISD------SERKTSSAESSSAES------------GSGSEEEEEEEEEEEEEGSTS 296
Query: 540 RELEEREEKLKKRPLLFERVAQKNARMAAEKHYSNTLKALGISDEFVSKKGQSGKVLEYF 599
E EE EE+ ++ E N+ A+E
Sbjct: 297 EESEEEEEEEEEE----EEETGSNSEEASE------------------------------ 322
Query: 600 NNQETKSVTEDKESFNEEEKIEERENGEENYFI-------DTNSQDSYKEKDEANEESEE 652
+ E +EEE E+ E EN+ + D +S +S + ++E E + +
Sbjct: 323 ---------QSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQ 373
Query: 653 EKSVEE 658
++ E
Sbjct: 374 SSALTE 379
>gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isoform
8 [Homo sapiens]
Length = 780
Score = 43.5 bits (101), Expect = 6e-04
Identities = 49/168 (29%), Positives = 78/168 (46%), Gaps = 40/168 (23%)
Query: 524 EQAVRKSEKER-MREYQRELEEREEKLKKRPLLFERVAQKNARMAAEKH-------YSNT 575
EQ RK E+ER MRE Q+E +RE+K ++R ER ++ AR H YS+
Sbjct: 167 EQLERKRERERKMREQQKE--QREQKERER-RAEERRKEREARREVSAHHRTMREDYSDK 223
Query: 576 LKA----------------LG-----ISDEFVSKKGQSGKVLEYFNNQETKSVTE----D 610
+KA LG + +E + ++ + + +++ S E +
Sbjct: 224 VKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAE 283
Query: 611 KESFNEEEKIEERENGEENYFIDTNSQDSYKEKDEANEESEEEKSVEE 658
S +EEE+ EE E EE + S++S +E++E EE EE S E
Sbjct: 284 SGSGSEEEEEEEEEEEEEG----STSEESEEEEEEEEEEEEETGSNSE 327
Score = 32.3 bits (72), Expect = 1.4
Identities = 32/138 (23%), Positives = 57/138 (41%), Gaps = 22/138 (15%)
Query: 523 REQAVRKSEKERMREYQRELEEREEKLKKRPLLFERVAQKNARMAAEKHYSNTLKALGIS 582
R++ KE+ RE++R REE+ K R E QK MA E
Sbjct: 105 RKEKKHARVKEKEREHERRKRHREEQDKARR---EWERQKRREMAREHSR---------- 151
Query: 583 DEFVSKKGQSGKVLEYFNNQETKSVTEDKESFNEEEKIEERENGEENYFIDTNSQDSYKE 642
++G G L ++ + E + E++K E+RE E + +++ KE
Sbjct: 152 ----RERGNDGVCLFRDRLEQLERKRERERKMREQQK-EQREQKER----ERRAEERRKE 202
Query: 643 KDEANEESEEEKSVEESH 660
++ E S +++ E +
Sbjct: 203 REARREVSAHHRTMREDY 220
Score = 30.4 bits (67), Expect = 5.4
Identities = 26/138 (18%), Positives = 57/138 (41%), Gaps = 8/138 (5%)
Query: 529 KSEKERMREYQRELEEREEKLKKRPLLFERVAQKNARMAAEKHYSNTLKALGISDEFVSK 588
K EK R+ +L++ + +K A+ + E+ + G + E +
Sbjct: 251 KEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEE 310
Query: 589 KGQSGKVLEYFNNQETKSVTEDK-ESFNEEEKIEERENGEENYFI-------DTNSQDSY 640
+ + + E ++ +E E +EEE E+ E EN+ + D +S +S
Sbjct: 311 EEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESE 370
Query: 641 KEKDEANEESEEEKSVEE 658
+ ++E E + + ++ E
Sbjct: 371 EAEEEVGEGTPQSSALTE 388
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.127 0.355
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,766,396
Number of Sequences: 37866
Number of extensions: 1389591
Number of successful extensions: 13317
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 141
Number of HSP's successfully gapped in prelim test: 550
Number of HSP's that attempted gapping in prelim test: 8186
Number of HSP's gapped (non-prelim): 3721
length of query: 660
length of database: 18,247,518
effective HSP length: 109
effective length of query: 551
effective length of database: 14,120,124
effective search space: 7780188324
effective search space used: 7780188324
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.