Guide to the Human Genome
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Search of human proteins with 18765700

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|18765700 engulfment and cell motility 1 isoform 1 [Homo
sapiens]
         (727 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|18765700 engulfment and cell motility 1 isoform 1 [Homo sapiens]  1453   0.0  
gi|19718769 engulfment and cell motility 2 [Homo sapiens]            1114   0.0  
gi|33469947 engulfment and cell motility 2 [Homo sapiens]            1114   0.0  
gi|87298935 engulfment and cell motility 3 [Homo sapiens]             750   0.0  
gi|86788140 engulfment and cell motility 1 isoform 2 [Homo sapiens]   503   e-142
gi|18765702 engulfment and cell motility 1 isoform 2 [Homo sapiens]   503   e-142
gi|118918407 spectrin repeat containing, nuclear envelope 2 isof...    39   0.022
gi|118918403 spectrin repeat containing, nuclear envelope 2 isof...    39   0.022
gi|118572599 formin homology 2 domain containing 1 [Homo sapiens]      35   0.19 
gi|110349756 zygin 2 isoform 2 [Homo sapiens]                          33   0.94 
gi|110349754 zygin 2 isoform 1 [Homo sapiens]                          33   0.94 
gi|187761324 shootin1 isoform a [Homo sapiens]                         33   1.2  
gi|50511340 shootin1 isoform b [Homo sapiens]                          33   1.2  
gi|169208122 PREDICTED: hypothetical protein isoform 1 [Homo sap...    32   1.6  
gi|55770834 centromere protein F [Homo sapiens]                        32   2.7  
gi|237858679 neurofascin isoform 3 precursor [Homo sapiens]            31   3.6  
gi|237858677 neurofascin isoform 2 precursor [Homo sapiens]            31   3.6  
gi|89903008 neurofascin isoform 4 precursor [Homo sapiens]             31   3.6  
gi|222537750 ankyrin repeat domain 30B [Homo sapiens]                  31   3.6  
gi|192807309 TNFAIP3 interacting protein 3 [Homo sapiens]              31   3.6  
gi|192807305 TNFAIP3 interacting protein 3 [Homo sapiens]              31   3.6  
gi|237858682 neurofascin isoform 6 precursor [Homo sapiens]            31   3.6  
gi|237858680 neurofascin isoform 5 precursor [Homo sapiens]            31   3.6  
gi|237858675 neurofascin isoform 1 precursor [Homo sapiens]            31   3.6  
gi|203098650 ELMO/CED-12 domain containing 3 isoform b [Homo sap...    31   3.6  
gi|203098539 ELMO/CED-12 domain containing 3 isoform b [Homo sap...    31   3.6  
gi|203098474 ELMO/CED-12 domain containing 3 isoform b [Homo sap...    31   3.6  
gi|21362032 ELMO/CED-12 domain containing 3 isoform a [Homo sapi...    31   3.6  
gi|239756999 PREDICTED: ankyrin repeat domain 62 [Homo sapiens]        31   4.6  
gi|239751514 PREDICTED: ankyrin repeat domain 62 isoform 4 [Homo...    31   4.6  

>gi|18765700 engulfment and cell motility 1 isoform 1 [Homo sapiens]
          Length = 727

 Score = 1453 bits (3761), Expect = 0.0
 Identities = 727/727 (100%), Positives = 727/727 (100%)

Query: 1   MPPPADIVKVAIEWPGAYPKLMEIDQKKPLSAIIKEVCDGWSLANHEYFALQHADSSNFY 60
           MPPPADIVKVAIEWPGAYPKLMEIDQKKPLSAIIKEVCDGWSLANHEYFALQHADSSNFY
Sbjct: 1   MPPPADIVKVAIEWPGAYPKLMEIDQKKPLSAIIKEVCDGWSLANHEYFALQHADSSNFY 60

Query: 61  ITEKNRNEIKNGTILRLTTSPAQNAQQLHERIQSSSMDAKLEALKDLASLSRDVTFAQEF 120
           ITEKNRNEIKNGTILRLTTSPAQNAQQLHERIQSSSMDAKLEALKDLASLSRDVTFAQEF
Sbjct: 61  ITEKNRNEIKNGTILRLTTSPAQNAQQLHERIQSSSMDAKLEALKDLASLSRDVTFAQEF 120

Query: 121 INLDGISLLTQMVESGTERYQKLQKIMKPCFGDMLSFTLTAFVELMDHGIVSWDTFSVAF 180
           INLDGISLLTQMVESGTERYQKLQKIMKPCFGDMLSFTLTAFVELMDHGIVSWDTFSVAF
Sbjct: 121 INLDGISLLTQMVESGTERYQKLQKIMKPCFGDMLSFTLTAFVELMDHGIVSWDTFSVAF 180

Query: 181 IKKIASFVNKSAIDISILQRSLAILESMVLNSHDLYQKVAQEITIGQLIPHLQGSDQEIQ 240
           IKKIASFVNKSAIDISILQRSLAILESMVLNSHDLYQKVAQEITIGQLIPHLQGSDQEIQ
Sbjct: 181 IKKIASFVNKSAIDISILQRSLAILESMVLNSHDLYQKVAQEITIGQLIPHLQGSDQEIQ 240

Query: 241 TYTIAVINALFLKAPDERRQEMANILAQKQLRSIILTHVIRAQRAINNEMAHQLYVLQVL 300
           TYTIAVINALFLKAPDERRQEMANILAQKQLRSIILTHVIRAQRAINNEMAHQLYVLQVL
Sbjct: 241 TYTIAVINALFLKAPDERRQEMANILAQKQLRSIILTHVIRAQRAINNEMAHQLYVLQVL 300

Query: 301 TFNLLEDRMMTKMDPQDQAQRDIIFELRRIAFDAESEPNNSSGSMEKRKSMYTRDYKKLG 360
           TFNLLEDRMMTKMDPQDQAQRDIIFELRRIAFDAESEPNNSSGSMEKRKSMYTRDYKKLG
Sbjct: 301 TFNLLEDRMMTKMDPQDQAQRDIIFELRRIAFDAESEPNNSSGSMEKRKSMYTRDYKKLG 360

Query: 361 FINHVNPAMDFTQTPPGMLALDNMLYFAKHHQDAYIRIVLENSSREDKHECPFGRSSIEL 420
           FINHVNPAMDFTQTPPGMLALDNMLYFAKHHQDAYIRIVLENSSREDKHECPFGRSSIEL
Sbjct: 361 FINHVNPAMDFTQTPPGMLALDNMLYFAKHHQDAYIRIVLENSSREDKHECPFGRSSIEL 420

Query: 421 TKMLCEILKVGELPSETCNDFHPMFFTHDRSFEEFFCICIQLLNKTWKEMRATSEDFNKV 480
           TKMLCEILKVGELPSETCNDFHPMFFTHDRSFEEFFCICIQLLNKTWKEMRATSEDFNKV
Sbjct: 421 TKMLCEILKVGELPSETCNDFHPMFFTHDRSFEEFFCICIQLLNKTWKEMRATSEDFNKV 480

Query: 481 MQVVKEQVMRALTTKPSSLDQFKSKLQNLSYTEILKIRQSERMNQEDFQSRPILELKEKI 540
           MQVVKEQVMRALTTKPSSLDQFKSKLQNLSYTEILKIRQSERMNQEDFQSRPILELKEKI
Sbjct: 481 MQVVKEQVMRALTTKPSSLDQFKSKLQNLSYTEILKIRQSERMNQEDFQSRPILELKEKI 540

Query: 541 QPEILELIKQQRLNRLVEGTCFRKLNARRRQDKFWYCRLSPNHKVLHYGDLEESPQGEVP 600
           QPEILELIKQQRLNRLVEGTCFRKLNARRRQDKFWYCRLSPNHKVLHYGDLEESPQGEVP
Sbjct: 541 QPEILELIKQQRLNRLVEGTCFRKLNARRRQDKFWYCRLSPNHKVLHYGDLEESPQGEVP 600

Query: 601 HDSLQDKLPVADIKAVVTGKDCPHMKEKGALKQNKEVLELAFSILYDSNCQLNFIAPDKH 660
           HDSLQDKLPVADIKAVVTGKDCPHMKEKGALKQNKEVLELAFSILYDSNCQLNFIAPDKH
Sbjct: 601 HDSLQDKLPVADIKAVVTGKDCPHMKEKGALKQNKEVLELAFSILYDSNCQLNFIAPDKH 660

Query: 661 EYCIWTDGLNALLGKDMMSDLTRNDLDTLLSMEIKLRLLDLENIQIPDAPPPIPKEPSNY 720
           EYCIWTDGLNALLGKDMMSDLTRNDLDTLLSMEIKLRLLDLENIQIPDAPPPIPKEPSNY
Sbjct: 661 EYCIWTDGLNALLGKDMMSDLTRNDLDTLLSMEIKLRLLDLENIQIPDAPPPIPKEPSNY 720

Query: 721 DFVYDCN 727
           DFVYDCN
Sbjct: 721 DFVYDCN 727


>gi|19718769 engulfment and cell motility 2 [Homo sapiens]
          Length = 720

 Score = 1114 bits (2881), Expect = 0.0
 Identities = 548/725 (75%), Positives = 643/725 (88%), Gaps = 9/725 (1%)

Query: 1   MPPPADIVKVAIEWPGAYPKLMEIDQKKPLSAIIKEVCDGWSLANHEYFALQHADSSNFY 60
           MPPP+DIVKVAIEWPGA  +L+EIDQK+PL++IIKEVCDGWSL N EY+ L++AD    Y
Sbjct: 1   MPPPSDIVKVAIEWPGANAQLLEIDQKRPLASIIKEVCDGWSLPNPEYYTLRYADGPQLY 60

Query: 61  ITEKNRNEIKNGTILRLTTSPAQNAQQLHERIQSSSMDAKLEALKDLASLSRDVTFAQEF 120
           ITE+ R++IKNGTIL+L  SP++ A+QL ER QSS+M+ +L+A+K+LA LS DVTFA EF
Sbjct: 61  ITEQTRSDIKNGTILQLAISPSRAARQLMERTQSSNMETRLDAMKELAKLSADVTFATEF 120

Query: 121 INLDGISLLTQMVESGTERYQKLQKIMKPCFGDMLSFTLTAFVELMDHGIVSWDTFSVAF 180
           IN+DGI +LT++VESGT+            + +ML+FTLTAF+ELMDHGIVSWD  S+ F
Sbjct: 121 INMDGIIVLTRLVESGTKLLSH--------YSEMLAFTLTAFLELMDHGIVSWDMVSITF 172

Query: 181 IKKIASFVNKSAIDISILQRSLAILESMVLNSHDLYQKVAQEITIGQLIPHLQGSDQEIQ 240
           IK+IA +V++  +D+SILQRSLAILESMVLNS  LYQK+A+EIT+GQLI HLQ S+QEIQ
Sbjct: 173 IKQIAGYVSQPMVDVSILQRSLAILESMVLNSQSLYQKIAEEITVGQLISHLQVSNQEIQ 232

Query: 241 TYTIAVINALFLKAPDERRQEMANILAQKQLRSIILTHVIRAQRAINNEMAHQLYVLQVL 300
           TY IA+INALFLKAP+++RQ+MAN  AQK LRSIIL HVIR  R I  EMAHQLYVLQVL
Sbjct: 233 TYAIALINALFLKAPEDKRQDMANAFAQKHLRSIILNHVIRGNRPIKTEMAHQLYVLQVL 292

Query: 301 TFNLLEDRMMTKMDPQDQAQRDIIFELRRIAFDAESEPNNSSGS-MEKRKSMYTRDYKKL 359
           TFNLLE+RMMTKMDP DQAQRDIIFELRRIAFDAES+P+N+ GS  EKRK+MYT+DYK L
Sbjct: 293 TFNLLEERMMTKMDPNDQAQRDIIFELRRIAFDAESDPSNAPGSGTEKRKAMYTKDYKML 352

Query: 360 GFINHVNPAMDFTQTPPGMLALDNMLYFAKHHQDAYIRIVLENSSREDKHECPFGRSSIE 419
           GF NH+NPAMDFTQTPPGMLALDNMLY AK HQD YIRIVLENSSREDKHECPFGRS+IE
Sbjct: 353 GFTNHINPAMDFTQTPPGMLALDNMLYLAKVHQDTYIRIVLENSSREDKHECPFGRSAIE 412

Query: 420 LTKMLCEILKVGELPSETCNDFHPMFFTHDRSFEEFFCICIQLLNKTWKEMRATSEDFNK 479
           LTKMLCEIL+VGELP+E  ND+HPMFFTHDR+FEE F ICIQLLNKTWKEMRAT+EDFNK
Sbjct: 413 LTKMLCEILQVGELPNEGRNDYHPMFFTHDRAFEELFGICIQLLNKTWKEMRATAEDFNK 472

Query: 480 VMQVVKEQVMRALTTKPSSLDQFKSKLQNLSYTEILKIRQSERMNQEDFQSRPILELKEK 539
           VMQVV+EQ+ RAL +KP+SLDQFKSKL++LSY+EIL++RQSERM+Q+DFQS PI+EL+EK
Sbjct: 473 VMQVVREQITRALPSKPNSLDQFKSKLRSLSYSEILRLRQSERMSQDDFQSPPIVELREK 532

Query: 540 IQPEILELIKQQRLNRLVEGTCFRKLNARRRQDKFWYCRLSPNHKVLHYGDLEESPQGEV 599
           IQPEILELIKQQRLNRL EG+ FRK+  RRRQ++FWYCRL+ NHKVLHYGDL+++PQGEV
Sbjct: 533 IQPEILELIKQQRLNRLCEGSSFRKIGNRRRQERFWYCRLALNHKVLHYGDLDDNPQGEV 592

Query: 600 PHDSLQDKLPVADIKAVVTGKDCPHMKEKGALKQNKEVLELAFSILYDSNCQLNFIAPDK 659
             +SLQ+K+PVADIKA+VTGKDCPHMKEK ALKQNKEVLELAFSILYD +  LNFIAP+K
Sbjct: 593 TFESLQEKIPVADIKAIVTGKDCPHMKEKSALKQNKEVLELAFSILYDPDETLNFIAPNK 652

Query: 660 HEYCIWTDGLNALLGKDMMSDLTRNDLDTLLSMEIKLRLLDLENIQIPDAPPPIPKEPSN 719
           +EYCIW DGL+ALLGKDM S+LT++DLDTLLSME+KLRLLDLENIQIP+APPPIPKEPS+
Sbjct: 653 YEYCIWIDGLSALLGKDMSSELTKSDLDTLLSMEMKLRLLDLENIQIPEAPPPIPKEPSS 712

Query: 720 YDFVY 724
           YDFVY
Sbjct: 713 YDFVY 717


>gi|33469947 engulfment and cell motility 2 [Homo sapiens]
          Length = 720

 Score = 1114 bits (2881), Expect = 0.0
 Identities = 548/725 (75%), Positives = 643/725 (88%), Gaps = 9/725 (1%)

Query: 1   MPPPADIVKVAIEWPGAYPKLMEIDQKKPLSAIIKEVCDGWSLANHEYFALQHADSSNFY 60
           MPPP+DIVKVAIEWPGA  +L+EIDQK+PL++IIKEVCDGWSL N EY+ L++AD    Y
Sbjct: 1   MPPPSDIVKVAIEWPGANAQLLEIDQKRPLASIIKEVCDGWSLPNPEYYTLRYADGPQLY 60

Query: 61  ITEKNRNEIKNGTILRLTTSPAQNAQQLHERIQSSSMDAKLEALKDLASLSRDVTFAQEF 120
           ITE+ R++IKNGTIL+L  SP++ A+QL ER QSS+M+ +L+A+K+LA LS DVTFA EF
Sbjct: 61  ITEQTRSDIKNGTILQLAISPSRAARQLMERTQSSNMETRLDAMKELAKLSADVTFATEF 120

Query: 121 INLDGISLLTQMVESGTERYQKLQKIMKPCFGDMLSFTLTAFVELMDHGIVSWDTFSVAF 180
           IN+DGI +LT++VESGT+            + +ML+FTLTAF+ELMDHGIVSWD  S+ F
Sbjct: 121 INMDGIIVLTRLVESGTKLLSH--------YSEMLAFTLTAFLELMDHGIVSWDMVSITF 172

Query: 181 IKKIASFVNKSAIDISILQRSLAILESMVLNSHDLYQKVAQEITIGQLIPHLQGSDQEIQ 240
           IK+IA +V++  +D+SILQRSLAILESMVLNS  LYQK+A+EIT+GQLI HLQ S+QEIQ
Sbjct: 173 IKQIAGYVSQPMVDVSILQRSLAILESMVLNSQSLYQKIAEEITVGQLISHLQVSNQEIQ 232

Query: 241 TYTIAVINALFLKAPDERRQEMANILAQKQLRSIILTHVIRAQRAINNEMAHQLYVLQVL 300
           TY IA+INALFLKAP+++RQ+MAN  AQK LRSIIL HVIR  R I  EMAHQLYVLQVL
Sbjct: 233 TYAIALINALFLKAPEDKRQDMANAFAQKHLRSIILNHVIRGNRPIKTEMAHQLYVLQVL 292

Query: 301 TFNLLEDRMMTKMDPQDQAQRDIIFELRRIAFDAESEPNNSSGS-MEKRKSMYTRDYKKL 359
           TFNLLE+RMMTKMDP DQAQRDIIFELRRIAFDAES+P+N+ GS  EKRK+MYT+DYK L
Sbjct: 293 TFNLLEERMMTKMDPNDQAQRDIIFELRRIAFDAESDPSNAPGSGTEKRKAMYTKDYKML 352

Query: 360 GFINHVNPAMDFTQTPPGMLALDNMLYFAKHHQDAYIRIVLENSSREDKHECPFGRSSIE 419
           GF NH+NPAMDFTQTPPGMLALDNMLY AK HQD YIRIVLENSSREDKHECPFGRS+IE
Sbjct: 353 GFTNHINPAMDFTQTPPGMLALDNMLYLAKVHQDTYIRIVLENSSREDKHECPFGRSAIE 412

Query: 420 LTKMLCEILKVGELPSETCNDFHPMFFTHDRSFEEFFCICIQLLNKTWKEMRATSEDFNK 479
           LTKMLCEIL+VGELP+E  ND+HPMFFTHDR+FEE F ICIQLLNKTWKEMRAT+EDFNK
Sbjct: 413 LTKMLCEILQVGELPNEGRNDYHPMFFTHDRAFEELFGICIQLLNKTWKEMRATAEDFNK 472

Query: 480 VMQVVKEQVMRALTTKPSSLDQFKSKLQNLSYTEILKIRQSERMNQEDFQSRPILELKEK 539
           VMQVV+EQ+ RAL +KP+SLDQFKSKL++LSY+EIL++RQSERM+Q+DFQS PI+EL+EK
Sbjct: 473 VMQVVREQITRALPSKPNSLDQFKSKLRSLSYSEILRLRQSERMSQDDFQSPPIVELREK 532

Query: 540 IQPEILELIKQQRLNRLVEGTCFRKLNARRRQDKFWYCRLSPNHKVLHYGDLEESPQGEV 599
           IQPEILELIKQQRLNRL EG+ FRK+  RRRQ++FWYCRL+ NHKVLHYGDL+++PQGEV
Sbjct: 533 IQPEILELIKQQRLNRLCEGSSFRKIGNRRRQERFWYCRLALNHKVLHYGDLDDNPQGEV 592

Query: 600 PHDSLQDKLPVADIKAVVTGKDCPHMKEKGALKQNKEVLELAFSILYDSNCQLNFIAPDK 659
             +SLQ+K+PVADIKA+VTGKDCPHMKEK ALKQNKEVLELAFSILYD +  LNFIAP+K
Sbjct: 593 TFESLQEKIPVADIKAIVTGKDCPHMKEKSALKQNKEVLELAFSILYDPDETLNFIAPNK 652

Query: 660 HEYCIWTDGLNALLGKDMMSDLTRNDLDTLLSMEIKLRLLDLENIQIPDAPPPIPKEPSN 719
           +EYCIW DGL+ALLGKDM S+LT++DLDTLLSME+KLRLLDLENIQIP+APPPIPKEPS+
Sbjct: 653 YEYCIWIDGLSALLGKDMSSELTKSDLDTLLSMEMKLRLLDLENIQIPEAPPPIPKEPSS 712

Query: 720 YDFVY 724
           YDFVY
Sbjct: 713 YDFVY 717


>gi|87298935 engulfment and cell motility 3 [Homo sapiens]
          Length = 773

 Score =  750 bits (1937), Expect = 0.0
 Identities = 376/730 (51%), Positives = 524/730 (71%), Gaps = 17/730 (2%)

Query: 1   MPPPADIVKVAIEWPGAYPKLMEIDQKKPLSAIIKEVCDGWSLANHEYFALQHADSSNFY 60
           M PP ++VK+AI+   A P+L+++DQ KPL+A++KEVCD WSL + E +ALQ AD    Y
Sbjct: 54  MAPPRNVVKIAIKMRDAIPQLIQLDQAKPLAAVLKEVCDAWSLTHSERYALQFADGHRRY 113

Query: 61  ITEKNRNEIKNGTILRLTTSPAQNAQQLHERIQSSSMDAKLEALKDLASLSRDVTFAQEF 120
           ITE NR EIKNG+IL L+T+P   A+QL   +QS+S + + EAL+ L  L+ D+ FA+E 
Sbjct: 114 ITENNRAEIKNGSILCLSTAPDLEAEQLLGGLQSNSPEGRREALRRLVPLASDMIFAREV 173

Query: 121 INLDGISLLTQMVESGTERYQKLQKIMKPCFGDMLSFTLTAFVELMDHGIVSWDTFSVAF 180
           I+ +G+ +L  ++E G +             G++L+ +L AF ELM+HG+VSW+T S+ F
Sbjct: 174 ISRNGLQILGTIIEDGDD------------LGEVLALSLRAFSELMEHGVVSWETLSIPF 221

Query: 181 IKKIASFVNKSAIDISILQRSLAILESMVLNSHDLYQKVAQEITIGQLIPHLQGSDQEIQ 240
           ++K+  +VN + +D S+   +L +LES+ L+S  L Q V  E+ + +L+ HLQ  +Q++Q
Sbjct: 222 VRKVVCYVNMNLMDASVPPLALGLLESVTLSSPALGQLVKSEVPLDRLLVHLQVMNQQLQ 281

Query: 241 TYTIAVINALFLKAPDERRQEMANILAQKQLRSIILTHVIRAQRAINNEMAHQLYVLQVL 300
           T  +A++ AL   A    R+ M + L Q+ LR  I  ++I +   + +EMAH LYVLQ L
Sbjct: 282 TKAMALLTALLQGASPVERKHMLDYLWQRNLRQFIYKNIIHSAAPMGDEMAHHLYVLQAL 341

Query: 301 TFNLLEDRMMTKMDPQDQAQRDIIFELRRIAFDAESEPNNSSGSMEKRKSMYTRDYKKLG 360
              LLE RM T +DP  Q QR+ +  LR+ AF+ E E + +  S ++R+S+  R+++KLG
Sbjct: 342 MLGLLEPRMRTPLDPYSQEQREQLQVLRQAAFEVEGESSGAGLSADRRRSLCAREFRKLG 401

Query: 361 FINHVNPAMDFTQTPPGMLALDNMLYFAKHHQDAYIRIVLENSSREDKHECPFGRSSIEL 420
           F N  NPA D  + PPG+LALDNMLYF+++   AY R VLENSSREDKHECPF R SI+L
Sbjct: 402 FSNS-NPAQDLERVPPGLLALDNMLYFSRNAPSAYSRFVLENSSREDKHECPFARGSIQL 460

Query: 421 TKMLCEILKVGELPSETCNDFHPMFFTHDRSFEEFFCICIQLLNKTWKEMRATSEDFNKV 480
           T +LCE+L+VGE  SET  DF PMFF  D+SF E FC+ IQLLNKTWKEMRAT EDF+KV
Sbjct: 461 TVLLCELLRVGEPCSETAQDFSPMFFGQDQSFHELFCVGIQLLNKTWKEMRATQEDFDKV 520

Query: 481 MQVVKEQVMRALTTKPSSLDQFKSKLQNLSYTEILKIRQSERMNQEDFQSRPILELKEKI 540
           MQVV+EQ+ R L  KP+SL+ F++K+  L+Y E+L++RQ+ER++QE   + PILEL+EK+
Sbjct: 521 MQVVREQLARTLALKPTSLELFRTKVNALTYGEVLRLRQTERLHQEGTLAPPILELREKL 580

Query: 541 QPEILELIKQQRLNRLVEGTCFRKLNARRRQDKFWYCRLSPNHKVLHYGDLEESPQGEVP 600
           +PE++ LI+QQRL RL EGT FRK+++RRRQDK W+C LSPNHK+L YGD+EE       
Sbjct: 581 KPELMGLIRQQRLLRLCEGTLFRKISSRRRQDKLWFCCLSPNHKLLQYGDMEEGASPPT- 639

Query: 601 HDSLQDKLPVADIKAVVTGKDCPHMKEKGALKQNKEVLELAFSILYD---SNCQLNFIAP 657
            +SL ++LPVAD++A++TGKDCPH++EKG+ KQNK++ ELAFSI YD       LNFIAP
Sbjct: 640 LESLPEQLPVADMRALLTGKDCPHVREKGSGKQNKDLYELAFSISYDRGEEEAYLNFIAP 699

Query: 658 DKHEYCIWTDGLNALLGKDMMSDLTRNDLDTLLSMEIKLRLLDLENIQIPDAPPPIPKEP 717
            K E+ +WTDGL+ALLG  M S+ TR DL+ LL+ME KLRLL+LEN+ IP+ PPP+P  P
Sbjct: 700 SKREFYLWTDGLSALLGSPMGSEQTRLDLEQLLTMETKLRLLELENVPIPERPPPVPPPP 759

Query: 718 SNYDFVYDCN 727
           +N++F YDC+
Sbjct: 760 TNFNFCYDCS 769


>gi|86788140 engulfment and cell motility 1 isoform 2 [Homo sapiens]
          Length = 247

 Score =  503 bits (1295), Expect = e-142
 Identities = 247/247 (100%), Positives = 247/247 (100%)

Query: 481 MQVVKEQVMRALTTKPSSLDQFKSKLQNLSYTEILKIRQSERMNQEDFQSRPILELKEKI 540
           MQVVKEQVMRALTTKPSSLDQFKSKLQNLSYTEILKIRQSERMNQEDFQSRPILELKEKI
Sbjct: 1   MQVVKEQVMRALTTKPSSLDQFKSKLQNLSYTEILKIRQSERMNQEDFQSRPILELKEKI 60

Query: 541 QPEILELIKQQRLNRLVEGTCFRKLNARRRQDKFWYCRLSPNHKVLHYGDLEESPQGEVP 600
           QPEILELIKQQRLNRLVEGTCFRKLNARRRQDKFWYCRLSPNHKVLHYGDLEESPQGEVP
Sbjct: 61  QPEILELIKQQRLNRLVEGTCFRKLNARRRQDKFWYCRLSPNHKVLHYGDLEESPQGEVP 120

Query: 601 HDSLQDKLPVADIKAVVTGKDCPHMKEKGALKQNKEVLELAFSILYDSNCQLNFIAPDKH 660
           HDSLQDKLPVADIKAVVTGKDCPHMKEKGALKQNKEVLELAFSILYDSNCQLNFIAPDKH
Sbjct: 121 HDSLQDKLPVADIKAVVTGKDCPHMKEKGALKQNKEVLELAFSILYDSNCQLNFIAPDKH 180

Query: 661 EYCIWTDGLNALLGKDMMSDLTRNDLDTLLSMEIKLRLLDLENIQIPDAPPPIPKEPSNY 720
           EYCIWTDGLNALLGKDMMSDLTRNDLDTLLSMEIKLRLLDLENIQIPDAPPPIPKEPSNY
Sbjct: 181 EYCIWTDGLNALLGKDMMSDLTRNDLDTLLSMEIKLRLLDLENIQIPDAPPPIPKEPSNY 240

Query: 721 DFVYDCN 727
           DFVYDCN
Sbjct: 241 DFVYDCN 247


>gi|18765702 engulfment and cell motility 1 isoform 2 [Homo sapiens]
          Length = 247

 Score =  503 bits (1295), Expect = e-142
 Identities = 247/247 (100%), Positives = 247/247 (100%)

Query: 481 MQVVKEQVMRALTTKPSSLDQFKSKLQNLSYTEILKIRQSERMNQEDFQSRPILELKEKI 540
           MQVVKEQVMRALTTKPSSLDQFKSKLQNLSYTEILKIRQSERMNQEDFQSRPILELKEKI
Sbjct: 1   MQVVKEQVMRALTTKPSSLDQFKSKLQNLSYTEILKIRQSERMNQEDFQSRPILELKEKI 60

Query: 541 QPEILELIKQQRLNRLVEGTCFRKLNARRRQDKFWYCRLSPNHKVLHYGDLEESPQGEVP 600
           QPEILELIKQQRLNRLVEGTCFRKLNARRRQDKFWYCRLSPNHKVLHYGDLEESPQGEVP
Sbjct: 61  QPEILELIKQQRLNRLVEGTCFRKLNARRRQDKFWYCRLSPNHKVLHYGDLEESPQGEVP 120

Query: 601 HDSLQDKLPVADIKAVVTGKDCPHMKEKGALKQNKEVLELAFSILYDSNCQLNFIAPDKH 660
           HDSLQDKLPVADIKAVVTGKDCPHMKEKGALKQNKEVLELAFSILYDSNCQLNFIAPDKH
Sbjct: 121 HDSLQDKLPVADIKAVVTGKDCPHMKEKGALKQNKEVLELAFSILYDSNCQLNFIAPDKH 180

Query: 661 EYCIWTDGLNALLGKDMMSDLTRNDLDTLLSMEIKLRLLDLENIQIPDAPPPIPKEPSNY 720
           EYCIWTDGLNALLGKDMMSDLTRNDLDTLLSMEIKLRLLDLENIQIPDAPPPIPKEPSNY
Sbjct: 181 EYCIWTDGLNALLGKDMMSDLTRNDLDTLLSMEIKLRLLDLENIQIPDAPPPIPKEPSNY 240

Query: 721 DFVYDCN 727
           DFVYDCN
Sbjct: 241 DFVYDCN 247


>gi|118918407 spectrin repeat containing, nuclear envelope 2 isoform 5
            [Homo sapiens]
          Length = 6907

 Score = 38.5 bits (88), Expect = 0.022
 Identities = 67/378 (17%), Positives = 149/378 (39%), Gaps = 52/378 (13%)

Query: 181  IKKIASFVNKSAIDISILQRSLAILESMVLNSHDLYQKVAQEITIG------QLIPHLQG 234
            ++K+    N+ ++    L++ LA+ +S+  N+  + QK+ ++           L   L  
Sbjct: 2289 LQKLQELENRLSLQDGTLKKILALAKSVKQNTSSVGQKIIKDDIKSLQCKQKDLENRLAS 2348

Query: 235  SDQEIQTYTIAVINALFLKAPDER--------RQEMANILAQKQLRSIILTHVIRAQRAI 286
            + QE++    +++ +   K   E+        R++ A    Q+  +       +     I
Sbjct: 2349 AKQEMECCLNSILKS---KRSTEKKGKFTLPGREKQATSDVQESTQESAAVEKLEEDWEI 2405

Query: 287  NNEMAHQLYVLQVLTFNLLEDRMMTKMDPQDQAQRDIIFELRRIAFDAESEPNNSSGSME 346
            N + A ++ + + L+ N  E    T+ + +       + EL+    + ++   N    +E
Sbjct: 2406 NKDSAVEMAMSKQLSLNAQESMKNTEDERK-------VNELQNQPLELDTMLRNEQ--LE 2456

Query: 347  KRKSMYTRDYKKLGFINHVNPAMDFTQTPPGMLALDNMLYFAKHHQDAYIRIVLENSSRE 406
            + + +YT+   K   I  +       +T  G L L N+ Y A+H  +    ++    ++E
Sbjct: 2457 EIEKLYTQLEAKKAAIKPLEQTECLNKTETGALVLHNIGYSAQHLDNLLQALITLKKNKE 2516

Query: 407  DKHECPFG---------RSSIELTKMLCEILKVGELPSETCNDFHPMFFTHDRSFEEFFC 457
             ++ C             SS++      E LKVG L S T  D    F       ++   
Sbjct: 2517 SQY-CVLRDFQEYLAAVESSMKALLTDKESLKVGPLDSVTYLDKIKKFIASIEKEKD--- 2572

Query: 458  ICIQLLNKTWKEMRATSEDFNKVM------------QVVKEQVMRALTTKPSSLDQFKSK 505
              +  L   W+ +     D +K +            + V++Q+ +  + +    D+F + 
Sbjct: 2573 -SLGNLKIKWENLSNHVTDMDKKLLESQIKQLEHGWEQVEQQIQKKYSQQVVEYDEFTTL 2631

Query: 506  LQNLSYTEILKIRQSERM 523
            +  +  TEI   +Q + +
Sbjct: 2632 MNKVQDTEISLQQQQQHL 2649



 Score = 33.5 bits (75), Expect = 0.72
 Identities = 23/91 (25%), Positives = 42/91 (46%), Gaps = 2/91 (2%)

Query: 461  QLLNKTWKEMRATSEDFNKVMQVVKEQVMRALTTKPSSLDQFKSKLQ--NLSYTEILKIR 518
            + L+   K ++   E    ++Q    +       K SS  + +  LQ  NLS  E +   
Sbjct: 4313 EALSLKLKTVKCNLEKVQMMLQEKHSEDQHPTILKKSSEPEHQEALQPVNLSELESIVTE 4372

Query: 519  QSERMNQEDFQSRPILELKEKIQPEILELIK 549
            + +   Q+DFQ + +LELK   Q + ++ I+
Sbjct: 4373 RPQFSRQKDFQQQQVLELKPMEQKDFIKFIE 4403


>gi|118918403 spectrin repeat containing, nuclear envelope 2 isoform 1
            [Homo sapiens]
          Length = 6885

 Score = 38.5 bits (88), Expect = 0.022
 Identities = 67/378 (17%), Positives = 149/378 (39%), Gaps = 52/378 (13%)

Query: 181  IKKIASFVNKSAIDISILQRSLAILESMVLNSHDLYQKVAQEITIG------QLIPHLQG 234
            ++K+    N+ ++    L++ LA+ +S+  N+  + QK+ ++           L   L  
Sbjct: 2289 LQKLQELENRLSLQDGTLKKILALAKSVKQNTSSVGQKIIKDDIKSLQCKQKDLENRLAS 2348

Query: 235  SDQEIQTYTIAVINALFLKAPDER--------RQEMANILAQKQLRSIILTHVIRAQRAI 286
            + QE++    +++ +   K   E+        R++ A    Q+  +       +     I
Sbjct: 2349 AKQEMECCLNSILKS---KRSTEKKGKFTLPGREKQATSDVQESTQESAAVEKLEEDWEI 2405

Query: 287  NNEMAHQLYVLQVLTFNLLEDRMMTKMDPQDQAQRDIIFELRRIAFDAESEPNNSSGSME 346
            N + A ++ + + L+ N  E    T+ + +       + EL+    + ++   N    +E
Sbjct: 2406 NKDSAVEMAMSKQLSLNAQESMKNTEDERK-------VNELQNQPLELDTMLRNEQ--LE 2456

Query: 347  KRKSMYTRDYKKLGFINHVNPAMDFTQTPPGMLALDNMLYFAKHHQDAYIRIVLENSSRE 406
            + + +YT+   K   I  +       +T  G L L N+ Y A+H  +    ++    ++E
Sbjct: 2457 EIEKLYTQLEAKKAAIKPLEQTECLNKTETGALVLHNIGYSAQHLDNLLQALITLKKNKE 2516

Query: 407  DKHECPFG---------RSSIELTKMLCEILKVGELPSETCNDFHPMFFTHDRSFEEFFC 457
             ++ C             SS++      E LKVG L S T  D    F       ++   
Sbjct: 2517 SQY-CVLRDFQEYLAAVESSMKALLTDKESLKVGPLDSVTYLDKIKKFIASIEKEKD--- 2572

Query: 458  ICIQLLNKTWKEMRATSEDFNKVM------------QVVKEQVMRALTTKPSSLDQFKSK 505
              +  L   W+ +     D +K +            + V++Q+ +  + +    D+F + 
Sbjct: 2573 -SLGNLKIKWENLSNHVTDMDKKLLESQIKQLEHGWEQVEQQIQKKYSQQVVEYDEFTTL 2631

Query: 506  LQNLSYTEILKIRQSERM 523
            +  +  TEI   +Q + +
Sbjct: 2632 MNKVQDTEISLQQQQQHL 2649



 Score = 33.5 bits (75), Expect = 0.72
 Identities = 23/91 (25%), Positives = 42/91 (46%), Gaps = 2/91 (2%)

Query: 461  QLLNKTWKEMRATSEDFNKVMQVVKEQVMRALTTKPSSLDQFKSKLQ--NLSYTEILKIR 518
            + L+   K ++   E    ++Q    +       K SS  + +  LQ  NLS  E +   
Sbjct: 4313 EALSLKLKTVKCNLEKVQMMLQEKHSEDQHPTILKKSSEPEHQEALQPVNLSELESIVTE 4372

Query: 519  QSERMNQEDFQSRPILELKEKIQPEILELIK 549
            + +   Q+DFQ + +LELK   Q + ++ I+
Sbjct: 4373 RPQFSRQKDFQQQQVLELKPMEQKDFIKFIE 4403


>gi|118572599 formin homology 2 domain containing 1 [Homo sapiens]
          Length = 1164

 Score = 35.4 bits (80), Expect = 0.19
 Identities = 43/212 (20%), Positives = 87/212 (41%), Gaps = 14/212 (6%)

Query: 74  ILRLTTSPAQNAQQLHERIQSSSMDAKLEALKDLASL-SRDVTFAQEFINLDGISLLTQM 132
           ILR   S   NA  + E++ SSS      +L  L  +   D     EF++ +G+S L ++
Sbjct: 111 ILRTQLSVRVNA--ILEKLYSSSGPELRRSLFSLKQIFQEDKDLVPEFVHSEGLSCLIRV 168

Query: 133 VESGTERYQKLQKIMKPCFGDMLSFTLTAFVELMDHGIVSWDTFSVAFIKKIASFVNKSA 192
             +    YQ     +    G ++ F       +     + W     A + ++   V K+A
Sbjct: 169 GAAADHNYQSY---ILRALGQLMLFVDGMLGVVAHSDTIQWLYTLCASLSRL---VVKTA 222

Query: 193 IDISIL----QRSLAILESMVLNSHDLYQKVAQEITIGQLIPHLQGSDQEIQTYTIAVIN 248
           + + ++      + A L    +NS            +  ++    G+D E+  YT+ +IN
Sbjct: 223 LKLLLVFVEYSENNAPLFIRAVNSVASTTGAPPWANLVSILEEKNGADPELLVYTVTLIN 282

Query: 249 ALFLKAPDERR-QEMANILAQKQLRSIILTHV 279
                 PD+    ++ + L Q+ + +++  H+
Sbjct: 283 KTLAALPDQDSFYDVTDALEQQGMEALVQRHL 314


>gi|110349756 zygin 2 isoform 2 [Homo sapiens]
          Length = 380

 Score = 33.1 bits (74), Expect = 0.94
 Identities = 22/108 (20%), Positives = 57/108 (52%), Gaps = 4/108 (3%)

Query: 305 LEDRMMTKMDPQDQAQRDIIFELRRIAFDAESEPNNSSGSMEKR-KSMYTRDYKKLGFIN 363
           +E+ M    DP+D         L  ++ + ++   +S+GS E+R K +   +  ++  + 
Sbjct: 169 IEEMMQESPDPEDDETPTQSDRLSMLSQEIQTLKRSSTGSYEERVKRLSVSELNEI--LE 226

Query: 364 HVNPAM-DFTQTPPGMLALDNMLYFAKHHQDAYIRIVLENSSREDKHE 410
            +  A+ ++++     LAL + L F K  ++++I +++E  +++ +H+
Sbjct: 227 EIETAIKEYSEELVQQLALRDELEFEKEVKNSFISVLIEVQNKQKEHK 274


>gi|110349754 zygin 2 isoform 1 [Homo sapiens]
          Length = 353

 Score = 33.1 bits (74), Expect = 0.94
 Identities = 22/108 (20%), Positives = 57/108 (52%), Gaps = 4/108 (3%)

Query: 305 LEDRMMTKMDPQDQAQRDIIFELRRIAFDAESEPNNSSGSMEKR-KSMYTRDYKKLGFIN 363
           +E+ M    DP+D         L  ++ + ++   +S+GS E+R K +   +  ++  + 
Sbjct: 169 IEEMMQESPDPEDDETPTQSDRLSMLSQEIQTLKRSSTGSYEERVKRLSVSELNEI--LE 226

Query: 364 HVNPAM-DFTQTPPGMLALDNMLYFAKHHQDAYIRIVLENSSREDKHE 410
            +  A+ ++++     LAL + L F K  ++++I +++E  +++ +H+
Sbjct: 227 EIETAIKEYSEELVQQLALRDELEFEKEVKNSFISVLIEVQNKQKEHK 274


>gi|187761324 shootin1 isoform a [Homo sapiens]
          Length = 631

 Score = 32.7 bits (73), Expect = 1.2
 Identities = 58/271 (21%), Positives = 110/271 (40%), Gaps = 51/271 (18%)

Query: 457 CICIQLLNKTWKEMRATSEDFNKVMQVVKEQVMRALTTKPSSLDQFKSKLQNLSYTEILK 516
           C+ +Q   K  KE+R      ++++ V +E+ + A+      L+  KSKL  +   E+ K
Sbjct: 135 CVSVQC-QKQIKELR------DQIVSVQEEKKILAI-----ELENLKSKLVEV-IEEVNK 181

Query: 517 IRQSER-MNQEDFQSRPILELKEKIQPEILELIKQQRLNRLVEGTCFRKLNARRRQDKFW 575
           ++Q +  +N E  + R +LE   ++    +E  ++ ++N  +E    RK      Q+ F 
Sbjct: 182 VKQEKTVLNSEVLEQRKVLEKCNRVSMLAVEEYEEMQVNLELEKD-LRKKAESFAQEMF- 239

Query: 576 YCRLSPNHKVLHYGDLEESPQGEVPHDSLQDKLPVADI-KAVVTGKDCPHMKEKGALKQN 634
                          +E++      H  LQ  +P   + KA+          E+  ++  
Sbjct: 240 ---------------IEQNKLKRQSHLLLQSSIPDQQLLKALDENAKLTQQLEEERIQHQ 284

Query: 635 KEVLELAFSI--------LYDSNCQLNFIAPDKHEYCIWTDGLNALLGKDMMSDLTRNDL 686
           ++V EL   +        +++   QL  +  DK E  +          K   S+    +L
Sbjct: 285 QKVKELEEQLENETLHKEIHNLKQQLELLEEDKKELEL----------KYQNSEEKARNL 334

Query: 687 DTLLSMEIKLRLLDLENIQIPDAPPPIPKEP 717
              +  E++ R+   EN   P  PPP P  P
Sbjct: 335 KHSVD-ELQKRVNQSENSVPPPPPPPPPLPP 364


>gi|50511340 shootin1 isoform b [Homo sapiens]
          Length = 456

 Score = 32.7 bits (73), Expect = 1.2
 Identities = 58/271 (21%), Positives = 110/271 (40%), Gaps = 51/271 (18%)

Query: 457 CICIQLLNKTWKEMRATSEDFNKVMQVVKEQVMRALTTKPSSLDQFKSKLQNLSYTEILK 516
           C+ +Q   K  KE+R      ++++ V +E+ + A+      L+  KSKL  +   E+ K
Sbjct: 135 CVSVQC-QKQIKELR------DQIVSVQEEKKILAI-----ELENLKSKLVEV-IEEVNK 181

Query: 517 IRQSER-MNQEDFQSRPILELKEKIQPEILELIKQQRLNRLVEGTCFRKLNARRRQDKFW 575
           ++Q +  +N E  + R +LE   ++    +E  ++ ++N  +E    RK      Q+ F 
Sbjct: 182 VKQEKTVLNSEVLEQRKVLEKCNRVSMLAVEEYEEMQVNLELEKD-LRKKAESFAQEMF- 239

Query: 576 YCRLSPNHKVLHYGDLEESPQGEVPHDSLQDKLPVADI-KAVVTGKDCPHMKEKGALKQN 634
                          +E++      H  LQ  +P   + KA+          E+  ++  
Sbjct: 240 ---------------IEQNKLKRQSHLLLQSSIPDQQLLKALDENAKLTQQLEEERIQHQ 284

Query: 635 KEVLELAFSI--------LYDSNCQLNFIAPDKHEYCIWTDGLNALLGKDMMSDLTRNDL 686
           ++V EL   +        +++   QL  +  DK E  +          K   S+    +L
Sbjct: 285 QKVKELEEQLENETLHKEIHNLKQQLELLEEDKKELEL----------KYQNSEEKARNL 334

Query: 687 DTLLSMEIKLRLLDLENIQIPDAPPPIPKEP 717
              +  E++ R+   EN   P  PPP P  P
Sbjct: 335 KHSVD-ELQKRVNQSENSVPPPPPPPPPLPP 364


>gi|169208122 PREDICTED: hypothetical protein isoform 1 [Homo
           sapiens]
          Length = 479

 Score = 32.3 bits (72), Expect = 1.6
 Identities = 33/125 (26%), Positives = 59/125 (47%), Gaps = 8/125 (6%)

Query: 453 EEFFCICIQLLNKTWKEMRATSEDFNKVMQVVKEQVMRALTTKPSSLDQFKSKLQNLSYT 512
           EE  C   + L +  + +R   E  ++  + + EQ  R    +    +Q K   Q     
Sbjct: 226 EERLCEQEERLREQEERLREQEERLHEQEERLCEQEERLCEQEERLCEQEKLPGQERLLE 285

Query: 513 EILKIRQSERMNQEDFQSRPILELKEKIQPEILELIKQQRL----NRLVEGTCFRKLNAR 568
           E+ K+ + ER  +E  Q R +LE +E++  E+ EL++Q+RL     RL +    R+L   
Sbjct: 286 EVEKLLEQERRQEE--QER-LLE-RERLLDEVEELLEQERLRQQDERLWQQETLRELERL 341

Query: 569 RRQDK 573
           R  ++
Sbjct: 342 RELER 346


>gi|55770834 centromere protein F [Homo sapiens]
          Length = 3114

 Score = 31.6 bits (70), Expect = 2.7
 Identities = 37/175 (21%), Positives = 71/175 (40%), Gaps = 9/175 (5%)

Query: 465  KTWKEMRATSEDFNKVMQVVKEQVMRALTTKPSSLDQFKSKLQNLSYTEILKIRQSERMN 524
            +T + +    ED +    VV E  + AL  K   L     K++     EI ++++S  + 
Sbjct: 880  ETSQRISKLQEDTSAHQNVVAE-TLSALENKEKELQLLNDKVET-EQAEIQELKKSNHLL 937

Query: 525  QEDFQSRPILE----LKEKIQPEILELIKQQRLNRLVEGTCFRKLNARRRQDKFWYCRLS 580
            ++  +   +L     L++K    I+ L K++      E    +++NA   Q+K     + 
Sbjct: 938  EDSLKELQLLSETLSLEKKEMSSIISLNKREIEELTQENGTLKEINASLNQEKM--NLIQ 995

Query: 581  PNHKVLHYGDLEESPQGEVPHDSLQDKLPVADIKAVVTGKDCPHMKEKGALKQNK 635
             +    +Y D  E    E+     Q+KL +   +   TG     + +K    Q K
Sbjct: 996  KSESFANYIDEREKSISELSDQYKQEKLILLQ-RCEETGNAYEDLSQKYKAAQEK 1049


>gi|237858679 neurofascin isoform 3 precursor [Homo sapiens]
          Length = 1174

 Score = 31.2 bits (69), Expect = 3.6
 Identities = 33/138 (23%), Positives = 56/138 (40%), Gaps = 28/138 (20%)

Query: 366 NPAMDFTQTPPGMLALDNMLYFAKHHQDAYIRIVLENSSREDKHECPFGRSSIELTKMLC 425
           N  +     PP ML+  N L          IR++L N +R D   CPF  S I   +   
Sbjct: 431 NAFVSVLDVPPRMLSPRNQL----------IRVILYNRTRLD---CPFFGSPIPTLRWF- 476

Query: 426 EILKVGELPSETCNDFH---------PMFFTHDRSFEEFFCICIQLLNKTWKEMRATSED 476
              K G+  +    ++H          M    D+    + C+   +L K   ++R   +D
Sbjct: 477 ---KNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGI--YTCVATNILGKAENQVRLEVKD 531

Query: 477 FNKVMQVVKEQVMRALTT 494
             ++ ++ ++QV R  TT
Sbjct: 532 PTRIYRMPEDQVARRGTT 549


>gi|237858677 neurofascin isoform 2 precursor [Homo sapiens]
          Length = 1189

 Score = 31.2 bits (69), Expect = 3.6
 Identities = 33/138 (23%), Positives = 56/138 (40%), Gaps = 28/138 (20%)

Query: 366 NPAMDFTQTPPGMLALDNMLYFAKHHQDAYIRIVLENSSREDKHECPFGRSSIELTKMLC 425
           N  +     PP ML+  N L          IR++L N +R D   CPF  S I   +   
Sbjct: 431 NAFVSVLDVPPRMLSPRNQL----------IRVILYNRTRLD---CPFFGSPIPTLRWF- 476

Query: 426 EILKVGELPSETCNDFH---------PMFFTHDRSFEEFFCICIQLLNKTWKEMRATSED 476
              K G+  +    ++H          M    D+    + C+   +L K   ++R   +D
Sbjct: 477 ---KNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGI--YTCVATNILGKAENQVRLEVKD 531

Query: 477 FNKVMQVVKEQVMRALTT 494
             ++ ++ ++QV R  TT
Sbjct: 532 PTRIYRMPEDQVARRGTT 549


>gi|89903008 neurofascin isoform 4 precursor [Homo sapiens]
          Length = 1169

 Score = 31.2 bits (69), Expect = 3.6
 Identities = 33/138 (23%), Positives = 56/138 (40%), Gaps = 28/138 (20%)

Query: 366 NPAMDFTQTPPGMLALDNMLYFAKHHQDAYIRIVLENSSREDKHECPFGRSSIELTKMLC 425
           N  +     PP ML+  N L          IR++L N +R D   CPF  S I   +   
Sbjct: 431 NAFVSVLDVPPRMLSPRNQL----------IRVILYNRTRLD---CPFFGSPIPTLRWF- 476

Query: 426 EILKVGELPSETCNDFH---------PMFFTHDRSFEEFFCICIQLLNKTWKEMRATSED 476
              K G+  +    ++H          M    D+    + C+   +L K   ++R   +D
Sbjct: 477 ---KNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGI--YTCVATNILGKAENQVRLEVKD 531

Query: 477 FNKVMQVVKEQVMRALTT 494
             ++ ++ ++QV R  TT
Sbjct: 532 PTRIYRMPEDQVARRGTT 549


>gi|222537750 ankyrin repeat domain 30B [Homo sapiens]
          Length = 1392

 Score = 31.2 bits (69), Expect = 3.6
 Identities = 47/192 (24%), Positives = 89/192 (46%), Gaps = 26/192 (13%)

Query: 461  QLLNKTWKEMRATSEDFNKVMQVVKEQVMRALTTKPSSLDQFKSKLQNLSYTEILKIRQS 520
            +L     +++ A  E       V+++++  A   K S L+  K+K +     E+  +R +
Sbjct: 961  ELKKDNCEQITAKMEQTKNKFCVLQKELSEAKEIK-SQLENQKAKWEQ----ELCSVRLT 1015

Query: 521  ERMNQEDFQSRPILELKEKIQPEILELIKQQRLNRLVEGTCFRKLNARRRQDKFWYCRLS 580
              +NQE+ + R +  LKEKI+PE  +L K+  + + +E T        R QD       S
Sbjct: 1016 --LNQEEEKRRNVDILKEKIRPE-EQLRKKLEVKQQLEQTL-------RIQDIELKSVTS 1065

Query: 581  PNHKVLHYGDLEESPQGEVPHDSLQDKLPVADIKAVVTGKDCPHMKEKGALKQNKEVLEL 640
              ++V H  + E     ++ H++   K  +A +K  V       +K +  +K+NK   ++
Sbjct: 1066 NLNQVSHTHESE----NDLFHENCMLKKEIAMLKLEVA-----TLKHQHQVKENKYFEDI 1116

Query: 641  AFSILYDSNCQL 652
               IL + N +L
Sbjct: 1117 --KILQEKNAEL 1126


>gi|192807309 TNFAIP3 interacting protein 3 [Homo sapiens]
          Length = 325

 Score = 31.2 bits (69), Expect = 3.6
 Identities = 43/208 (20%), Positives = 88/208 (42%), Gaps = 21/208 (10%)

Query: 460 IQLLNKTWKEMRATSEDFNKVMQVVKEQVMRALTTKPSSLDQFKSKLQNLSYTEILKIRQ 519
           I+ L K  KE+   ++ +++  + +KE   R +    + LD  +  L         + R+
Sbjct: 40  IRCLEKQRKELLEVNQQWDQQFRSMKELYERKVAELKTKLDAAERFLSTREKDPHQRQRK 99

Query: 520 SERMNQEDFQ---SRPILELKEKIQPEI-LELIKQQRLNRLVEGTCFRKLNARRRQDKFW 575
            +R  ++D Q   +R  L+ +EK +  +  EL + +  N+L++G    K     ++ + +
Sbjct: 100 DDRQREDDRQRDLTRDRLQREEKEKERLNEELHELKEENKLLKG----KNTLANKEKEHY 155

Query: 576 YCRLSPNHKVLHYG---------DLEESPQGEVPHDSLQDKLPVADIKAVVTGKDC-PHM 625
            C +   +K L            D     + E  H+ ++ ++ V   +  +  +D     
Sbjct: 156 ECEIKRLNKALQDALNIKCSFSEDCLRKSRVEFCHEEMRTEMEVLKQQVQIYEEDFKKER 215

Query: 626 KEKGALKQNKEVLELAFSILYDSNCQLN 653
            ++  L Q KE L+    I   S  QLN
Sbjct: 216 SDRERLNQEKEELQ---QINETSQSQLN 240


>gi|192807305 TNFAIP3 interacting protein 3 [Homo sapiens]
          Length = 325

 Score = 31.2 bits (69), Expect = 3.6
 Identities = 43/208 (20%), Positives = 88/208 (42%), Gaps = 21/208 (10%)

Query: 460 IQLLNKTWKEMRATSEDFNKVMQVVKEQVMRALTTKPSSLDQFKSKLQNLSYTEILKIRQ 519
           I+ L K  KE+   ++ +++  + +KE   R +    + LD  +  L         + R+
Sbjct: 40  IRCLEKQRKELLEVNQQWDQQFRSMKELYERKVAELKTKLDAAERFLSTREKDPHQRQRK 99

Query: 520 SERMNQEDFQ---SRPILELKEKIQPEI-LELIKQQRLNRLVEGTCFRKLNARRRQDKFW 575
            +R  ++D Q   +R  L+ +EK +  +  EL + +  N+L++G    K     ++ + +
Sbjct: 100 DDRQREDDRQRDLTRDRLQREEKEKERLNEELHELKEENKLLKG----KNTLANKEKEHY 155

Query: 576 YCRLSPNHKVLHYG---------DLEESPQGEVPHDSLQDKLPVADIKAVVTGKDC-PHM 625
            C +   +K L            D     + E  H+ ++ ++ V   +  +  +D     
Sbjct: 156 ECEIKRLNKALQDALNIKCSFSEDCLRKSRVEFCHEEMRTEMEVLKQQVQIYEEDFKKER 215

Query: 626 KEKGALKQNKEVLELAFSILYDSNCQLN 653
            ++  L Q KE L+    I   S  QLN
Sbjct: 216 SDRERLNQEKEELQ---QINETSQSQLN 240


>gi|237858682 neurofascin isoform 6 precursor [Homo sapiens]
          Length = 613

 Score = 31.2 bits (69), Expect = 3.6
 Identities = 33/138 (23%), Positives = 56/138 (40%), Gaps = 28/138 (20%)

Query: 366 NPAMDFTQTPPGMLALDNMLYFAKHHQDAYIRIVLENSSREDKHECPFGRSSIELTKMLC 425
           N  +     PP ML+  N L          IR++L N +R D   CPF  S I   +   
Sbjct: 414 NAFVSVLDVPPRMLSPRNQL----------IRVILYNRTRLD---CPFFGSPIPTLRWF- 459

Query: 426 EILKVGELPSETCNDFH---------PMFFTHDRSFEEFFCICIQLLNKTWKEMRATSED 476
              K G+  +    ++H          M    D+    + C+   +L K   ++R   +D
Sbjct: 460 ---KNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGI--YTCVATNILGKAENQVRLEVKD 514

Query: 477 FNKVMQVVKEQVMRALTT 494
             ++ ++ ++QV R  TT
Sbjct: 515 PTRIYRMPEDQVARRGTT 532


>gi|237858680 neurofascin isoform 5 precursor [Homo sapiens]
          Length = 619

 Score = 31.2 bits (69), Expect = 3.6
 Identities = 33/138 (23%), Positives = 56/138 (40%), Gaps = 28/138 (20%)

Query: 366 NPAMDFTQTPPGMLALDNMLYFAKHHQDAYIRIVLENSSREDKHECPFGRSSIELTKMLC 425
           N  +     PP ML+  N L          IR++L N +R D   CPF  S I   +   
Sbjct: 420 NAFVSVLDVPPRMLSPRNQL----------IRVILYNRTRLD---CPFFGSPIPTLRWF- 465

Query: 426 EILKVGELPSETCNDFH---------PMFFTHDRSFEEFFCICIQLLNKTWKEMRATSED 476
              K G+  +    ++H          M    D+    + C+   +L K   ++R   +D
Sbjct: 466 ---KNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGI--YTCVATNILGKAENQVRLEVKD 520

Query: 477 FNKVMQVVKEQVMRALTT 494
             ++ ++ ++QV R  TT
Sbjct: 521 PTRIYRMPEDQVARRGTT 538


>gi|237858675 neurofascin isoform 1 precursor [Homo sapiens]
          Length = 1240

 Score = 31.2 bits (69), Expect = 3.6
 Identities = 33/138 (23%), Positives = 56/138 (40%), Gaps = 28/138 (20%)

Query: 366 NPAMDFTQTPPGMLALDNMLYFAKHHQDAYIRIVLENSSREDKHECPFGRSSIELTKMLC 425
           N  +     PP ML+  N L          IR++L N +R D   CPF  S I   +   
Sbjct: 420 NAFVSVLDVPPRMLSPRNQL----------IRVILYNRTRLD---CPFFGSPIPTLRWF- 465

Query: 426 EILKVGELPSETCNDFH---------PMFFTHDRSFEEFFCICIQLLNKTWKEMRATSED 476
              K G+  +    ++H          M    D+    + C+   +L K   ++R   +D
Sbjct: 466 ---KNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGI--YTCVATNILGKAENQVRLEVKD 520

Query: 477 FNKVMQVVKEQVMRALTT 494
             ++ ++ ++QV R  TT
Sbjct: 521 PTRIYRMPEDQVARRGTT 538


>gi|203098650 ELMO/CED-12 domain containing 3 isoform b [Homo
           sapiens]
          Length = 381

 Score = 31.2 bits (69), Expect = 3.6
 Identities = 40/195 (20%), Positives = 75/195 (38%), Gaps = 20/195 (10%)

Query: 312 KMDPQDQAQRDIIFELRRIAFDAESEPNNSSGSMEKRK--------SMYTRDYKKLGFIN 363
           K+  + + +RD++  + +   D++   +        +K        +++   ++ LGF  
Sbjct: 144 KLHQRLREERDLVLTIAQCGLDSQDPVHGRVLQTIYKKLTGSKFDCALHGNHWEDLGF-Q 202

Query: 364 HVNPAMDFTQTPPGMLALDNMLYFAKHHQDAYIRIVLENSSREDKHECPFGRSSIELTKM 423
             NPA D      G LAL ++LY     +   +   +   SR    + PF   S+ +T +
Sbjct: 203 GANPATDLRGA--GFLALLHLLYLVMDSKTLPMAQEIFRLSRHHIQQFPFCLMSVNITHI 260

Query: 424 LCEILKVGELPSETCNDFHPMFFTHDRSFEEFFCICIQLLNKTWKEMRATSEDFNKVMQ- 482
             + L+  E  S  CN    +          F+      L   W+  R T  D   V++ 
Sbjct: 261 AIQALR-EECLSRECNRQQKVI----PVVNSFYAATFLHLAHVWRTQRKTISDSGFVLKE 315

Query: 483 ---VVKEQVMRALTT 494
              + K+   R L T
Sbjct: 316 LEVLAKKSPRRLLKT 330


>gi|203098539 ELMO/CED-12 domain containing 3 isoform b [Homo
           sapiens]
          Length = 381

 Score = 31.2 bits (69), Expect = 3.6
 Identities = 40/195 (20%), Positives = 75/195 (38%), Gaps = 20/195 (10%)

Query: 312 KMDPQDQAQRDIIFELRRIAFDAESEPNNSSGSMEKRK--------SMYTRDYKKLGFIN 363
           K+  + + +RD++  + +   D++   +        +K        +++   ++ LGF  
Sbjct: 144 KLHQRLREERDLVLTIAQCGLDSQDPVHGRVLQTIYKKLTGSKFDCALHGNHWEDLGF-Q 202

Query: 364 HVNPAMDFTQTPPGMLALDNMLYFAKHHQDAYIRIVLENSSREDKHECPFGRSSIELTKM 423
             NPA D      G LAL ++LY     +   +   +   SR    + PF   S+ +T +
Sbjct: 203 GANPATDLRGA--GFLALLHLLYLVMDSKTLPMAQEIFRLSRHHIQQFPFCLMSVNITHI 260

Query: 424 LCEILKVGELPSETCNDFHPMFFTHDRSFEEFFCICIQLLNKTWKEMRATSEDFNKVMQ- 482
             + L+  E  S  CN    +          F+      L   W+  R T  D   V++ 
Sbjct: 261 AIQALR-EECLSRECNRQQKVI----PVVNSFYAATFLHLAHVWRTQRKTISDSGFVLKE 315

Query: 483 ---VVKEQVMRALTT 494
              + K+   R L T
Sbjct: 316 LEVLAKKSPRRLLKT 330


>gi|203098474 ELMO/CED-12 domain containing 3 isoform b [Homo
           sapiens]
          Length = 381

 Score = 31.2 bits (69), Expect = 3.6
 Identities = 40/195 (20%), Positives = 75/195 (38%), Gaps = 20/195 (10%)

Query: 312 KMDPQDQAQRDIIFELRRIAFDAESEPNNSSGSMEKRK--------SMYTRDYKKLGFIN 363
           K+  + + +RD++  + +   D++   +        +K        +++   ++ LGF  
Sbjct: 144 KLHQRLREERDLVLTIAQCGLDSQDPVHGRVLQTIYKKLTGSKFDCALHGNHWEDLGF-Q 202

Query: 364 HVNPAMDFTQTPPGMLALDNMLYFAKHHQDAYIRIVLENSSREDKHECPFGRSSIELTKM 423
             NPA D      G LAL ++LY     +   +   +   SR    + PF   S+ +T +
Sbjct: 203 GANPATDLRGA--GFLALLHLLYLVMDSKTLPMAQEIFRLSRHHIQQFPFCLMSVNITHI 260

Query: 424 LCEILKVGELPSETCNDFHPMFFTHDRSFEEFFCICIQLLNKTWKEMRATSEDFNKVMQ- 482
             + L+  E  S  CN    +          F+      L   W+  R T  D   V++ 
Sbjct: 261 AIQALR-EECLSRECNRQQKVI----PVVNSFYAATFLHLAHVWRTQRKTISDSGFVLKE 315

Query: 483 ---VVKEQVMRALTT 494
              + K+   R L T
Sbjct: 316 LEVLAKKSPRRLLKT 330


>gi|21362032 ELMO/CED-12 domain containing 3 isoform a [Homo
           sapiens]
          Length = 391

 Score = 31.2 bits (69), Expect = 3.6
 Identities = 37/181 (20%), Positives = 70/181 (38%), Gaps = 16/181 (8%)

Query: 312 KMDPQDQAQRDIIFELRRIAFDAESEPNNSSGSMEKRK--------SMYTRDYKKLGFIN 363
           K+  + + +RD++  + +   D++   +        +K        +++   ++ LGF  
Sbjct: 144 KLHQRLREERDLVLTIAQCGLDSQDPVHGRVLQTIYKKLTGSKFDCALHGNHWEDLGF-Q 202

Query: 364 HVNPAMDFTQTPPGMLALDNMLYFAKHHQDAYIRIVLENSSREDKHECPFGRSSIELTKM 423
             NPA D      G LAL ++LY     +   +   +   SR    + PF   S+ +T +
Sbjct: 203 GANPATDLRGA--GFLALLHLLYLVMDSKTLPMAQEIFRLSRHHIQQFPFCLMSVNITHI 260

Query: 424 LCEILKVGELPSETCNDFHPMFFTHDRSFEEFFCICIQLLNKTWKEMRATSEDFNKVMQV 483
             + L+  E  S  CN    +          F+      L   W+  R T  D   V++ 
Sbjct: 261 AIQALR-EECLSRECNRQQKVI----PVVNSFYAATFLHLAHVWRTQRKTISDSGFVLKG 315

Query: 484 V 484
           V
Sbjct: 316 V 316


>gi|239756999 PREDICTED: ankyrin repeat domain 62 [Homo sapiens]
          Length = 917

 Score = 30.8 bits (68), Expect = 4.6
 Identities = 54/226 (23%), Positives = 88/226 (38%), Gaps = 41/226 (18%)

Query: 450 RSFEEFFCICIQLLNKTWKEMRATSEDFNKVMQVVKEQVMRALTTKPSSLDQFKSKLQNL 509
           RS E+  C C +L  K  K     S     V+Q V  +  +  +       Q K KL NL
Sbjct: 430 RSIEDQKCYCERLKVKFQKMKNNIS-----VLQKVLSETDKTKSQSEHQNLQGKKKLCNL 484

Query: 510 SYTEILKIRQSERMNQEDFQSRPILELK--EKIQPEILELIKQQRLN--------RLVEG 559
            +  IL+ ++ ER+  E+   + I ELK  E+      E+ KQ +L         + V  
Sbjct: 485 RF--ILQQQEEERIKAEELYEKDIEELKIMEEQYRTQTEVKKQSKLTLKSLEVELKTVRS 542

Query: 560 TCFRKLNARRRQDKFWYCRLSPNHKVLHYGDLEESPQGEVPHDSLQDKLPVADIKAVVTG 619
              +  +   R+   W      NH +      +E  +  +  D+++ +    + K     
Sbjct: 543 NSNQNFHTHERERDLW----QENHLM-----RDEIARLRLEIDTIKHQNQETENKYF--- 590

Query: 620 KDCPHMKEKG-----ALKQNKEVL-------ELAFSILYDSNCQLN 653
           KD   +KE        LK+N+E L           ++L D N  LN
Sbjct: 591 KDIEIIKENNEDLEKTLKRNEETLTKTITRYSKELNVLMDENTMLN 636


>gi|239751514 PREDICTED: ankyrin repeat domain 62 isoform 4 [Homo
           sapiens]
          Length = 917

 Score = 30.8 bits (68), Expect = 4.6
 Identities = 54/226 (23%), Positives = 88/226 (38%), Gaps = 41/226 (18%)

Query: 450 RSFEEFFCICIQLLNKTWKEMRATSEDFNKVMQVVKEQVMRALTTKPSSLDQFKSKLQNL 509
           RS E+  C C +L  K  K     S     V+Q V  +  +  +       Q K KL NL
Sbjct: 430 RSIEDQKCYCERLKVKFQKMKNNIS-----VLQKVLSETDKTKSQSEHQNLQGKKKLCNL 484

Query: 510 SYTEILKIRQSERMNQEDFQSRPILELK--EKIQPEILELIKQQRLN--------RLVEG 559
            +  IL+ ++ ER+  E+   + I ELK  E+      E+ KQ +L         + V  
Sbjct: 485 RF--ILQQQEEERIKAEELYEKDIEELKIMEEQYRTQTEVKKQSKLTLKSLEVELKTVRS 542

Query: 560 TCFRKLNARRRQDKFWYCRLSPNHKVLHYGDLEESPQGEVPHDSLQDKLPVADIKAVVTG 619
              +  +   R+   W      NH +      +E  +  +  D+++ +    + K     
Sbjct: 543 NSNQNFHTHERERDLW----QENHLM-----RDEIARLRLEIDTIKHQNQETENKYF--- 590

Query: 620 KDCPHMKEKG-----ALKQNKEVL-------ELAFSILYDSNCQLN 653
           KD   +KE        LK+N+E L           ++L D N  LN
Sbjct: 591 KDIEIIKENNEDLEKTLKRNEETLTKTITRYSKELNVLMDENTMLN 636


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.134    0.389 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,902,615
Number of Sequences: 37866
Number of extensions: 1078556
Number of successful extensions: 3386
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 36
Number of HSP's that attempted gapping in prelim test: 3349
Number of HSP's gapped (non-prelim): 66
length of query: 727
length of database: 18,247,518
effective HSP length: 110
effective length of query: 617
effective length of database: 14,082,258
effective search space: 8688753186
effective search space used: 8688753186
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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