BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|18765700 engulfment and cell motility 1 isoform 1 [Homo sapiens] (727 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|18765700 engulfment and cell motility 1 isoform 1 [Homo sapiens] 1453 0.0 gi|19718769 engulfment and cell motility 2 [Homo sapiens] 1114 0.0 gi|33469947 engulfment and cell motility 2 [Homo sapiens] 1114 0.0 gi|87298935 engulfment and cell motility 3 [Homo sapiens] 750 0.0 gi|86788140 engulfment and cell motility 1 isoform 2 [Homo sapiens] 503 e-142 gi|18765702 engulfment and cell motility 1 isoform 2 [Homo sapiens] 503 e-142 gi|118918407 spectrin repeat containing, nuclear envelope 2 isof... 39 0.022 gi|118918403 spectrin repeat containing, nuclear envelope 2 isof... 39 0.022 gi|118572599 formin homology 2 domain containing 1 [Homo sapiens] 35 0.19 gi|110349756 zygin 2 isoform 2 [Homo sapiens] 33 0.94 gi|110349754 zygin 2 isoform 1 [Homo sapiens] 33 0.94 gi|187761324 shootin1 isoform a [Homo sapiens] 33 1.2 gi|50511340 shootin1 isoform b [Homo sapiens] 33 1.2 gi|169208122 PREDICTED: hypothetical protein isoform 1 [Homo sap... 32 1.6 gi|55770834 centromere protein F [Homo sapiens] 32 2.7 gi|237858679 neurofascin isoform 3 precursor [Homo sapiens] 31 3.6 gi|237858677 neurofascin isoform 2 precursor [Homo sapiens] 31 3.6 gi|89903008 neurofascin isoform 4 precursor [Homo sapiens] 31 3.6 gi|222537750 ankyrin repeat domain 30B [Homo sapiens] 31 3.6 gi|192807309 TNFAIP3 interacting protein 3 [Homo sapiens] 31 3.6 gi|192807305 TNFAIP3 interacting protein 3 [Homo sapiens] 31 3.6 gi|237858682 neurofascin isoform 6 precursor [Homo sapiens] 31 3.6 gi|237858680 neurofascin isoform 5 precursor [Homo sapiens] 31 3.6 gi|237858675 neurofascin isoform 1 precursor [Homo sapiens] 31 3.6 gi|203098650 ELMO/CED-12 domain containing 3 isoform b [Homo sap... 31 3.6 gi|203098539 ELMO/CED-12 domain containing 3 isoform b [Homo sap... 31 3.6 gi|203098474 ELMO/CED-12 domain containing 3 isoform b [Homo sap... 31 3.6 gi|21362032 ELMO/CED-12 domain containing 3 isoform a [Homo sapi... 31 3.6 gi|239756999 PREDICTED: ankyrin repeat domain 62 [Homo sapiens] 31 4.6 gi|239751514 PREDICTED: ankyrin repeat domain 62 isoform 4 [Homo... 31 4.6 >gi|18765700 engulfment and cell motility 1 isoform 1 [Homo sapiens] Length = 727 Score = 1453 bits (3761), Expect = 0.0 Identities = 727/727 (100%), Positives = 727/727 (100%) Query: 1 MPPPADIVKVAIEWPGAYPKLMEIDQKKPLSAIIKEVCDGWSLANHEYFALQHADSSNFY 60 MPPPADIVKVAIEWPGAYPKLMEIDQKKPLSAIIKEVCDGWSLANHEYFALQHADSSNFY Sbjct: 1 MPPPADIVKVAIEWPGAYPKLMEIDQKKPLSAIIKEVCDGWSLANHEYFALQHADSSNFY 60 Query: 61 ITEKNRNEIKNGTILRLTTSPAQNAQQLHERIQSSSMDAKLEALKDLASLSRDVTFAQEF 120 ITEKNRNEIKNGTILRLTTSPAQNAQQLHERIQSSSMDAKLEALKDLASLSRDVTFAQEF Sbjct: 61 ITEKNRNEIKNGTILRLTTSPAQNAQQLHERIQSSSMDAKLEALKDLASLSRDVTFAQEF 120 Query: 121 INLDGISLLTQMVESGTERYQKLQKIMKPCFGDMLSFTLTAFVELMDHGIVSWDTFSVAF 180 INLDGISLLTQMVESGTERYQKLQKIMKPCFGDMLSFTLTAFVELMDHGIVSWDTFSVAF Sbjct: 121 INLDGISLLTQMVESGTERYQKLQKIMKPCFGDMLSFTLTAFVELMDHGIVSWDTFSVAF 180 Query: 181 IKKIASFVNKSAIDISILQRSLAILESMVLNSHDLYQKVAQEITIGQLIPHLQGSDQEIQ 240 IKKIASFVNKSAIDISILQRSLAILESMVLNSHDLYQKVAQEITIGQLIPHLQGSDQEIQ Sbjct: 181 IKKIASFVNKSAIDISILQRSLAILESMVLNSHDLYQKVAQEITIGQLIPHLQGSDQEIQ 240 Query: 241 TYTIAVINALFLKAPDERRQEMANILAQKQLRSIILTHVIRAQRAINNEMAHQLYVLQVL 300 TYTIAVINALFLKAPDERRQEMANILAQKQLRSIILTHVIRAQRAINNEMAHQLYVLQVL Sbjct: 241 TYTIAVINALFLKAPDERRQEMANILAQKQLRSIILTHVIRAQRAINNEMAHQLYVLQVL 300 Query: 301 TFNLLEDRMMTKMDPQDQAQRDIIFELRRIAFDAESEPNNSSGSMEKRKSMYTRDYKKLG 360 TFNLLEDRMMTKMDPQDQAQRDIIFELRRIAFDAESEPNNSSGSMEKRKSMYTRDYKKLG Sbjct: 301 TFNLLEDRMMTKMDPQDQAQRDIIFELRRIAFDAESEPNNSSGSMEKRKSMYTRDYKKLG 360 Query: 361 FINHVNPAMDFTQTPPGMLALDNMLYFAKHHQDAYIRIVLENSSREDKHECPFGRSSIEL 420 FINHVNPAMDFTQTPPGMLALDNMLYFAKHHQDAYIRIVLENSSREDKHECPFGRSSIEL Sbjct: 361 FINHVNPAMDFTQTPPGMLALDNMLYFAKHHQDAYIRIVLENSSREDKHECPFGRSSIEL 420 Query: 421 TKMLCEILKVGELPSETCNDFHPMFFTHDRSFEEFFCICIQLLNKTWKEMRATSEDFNKV 480 TKMLCEILKVGELPSETCNDFHPMFFTHDRSFEEFFCICIQLLNKTWKEMRATSEDFNKV Sbjct: 421 TKMLCEILKVGELPSETCNDFHPMFFTHDRSFEEFFCICIQLLNKTWKEMRATSEDFNKV 480 Query: 481 MQVVKEQVMRALTTKPSSLDQFKSKLQNLSYTEILKIRQSERMNQEDFQSRPILELKEKI 540 MQVVKEQVMRALTTKPSSLDQFKSKLQNLSYTEILKIRQSERMNQEDFQSRPILELKEKI Sbjct: 481 MQVVKEQVMRALTTKPSSLDQFKSKLQNLSYTEILKIRQSERMNQEDFQSRPILELKEKI 540 Query: 541 QPEILELIKQQRLNRLVEGTCFRKLNARRRQDKFWYCRLSPNHKVLHYGDLEESPQGEVP 600 QPEILELIKQQRLNRLVEGTCFRKLNARRRQDKFWYCRLSPNHKVLHYGDLEESPQGEVP Sbjct: 541 QPEILELIKQQRLNRLVEGTCFRKLNARRRQDKFWYCRLSPNHKVLHYGDLEESPQGEVP 600 Query: 601 HDSLQDKLPVADIKAVVTGKDCPHMKEKGALKQNKEVLELAFSILYDSNCQLNFIAPDKH 660 HDSLQDKLPVADIKAVVTGKDCPHMKEKGALKQNKEVLELAFSILYDSNCQLNFIAPDKH Sbjct: 601 HDSLQDKLPVADIKAVVTGKDCPHMKEKGALKQNKEVLELAFSILYDSNCQLNFIAPDKH 660 Query: 661 EYCIWTDGLNALLGKDMMSDLTRNDLDTLLSMEIKLRLLDLENIQIPDAPPPIPKEPSNY 720 EYCIWTDGLNALLGKDMMSDLTRNDLDTLLSMEIKLRLLDLENIQIPDAPPPIPKEPSNY Sbjct: 661 EYCIWTDGLNALLGKDMMSDLTRNDLDTLLSMEIKLRLLDLENIQIPDAPPPIPKEPSNY 720 Query: 721 DFVYDCN 727 DFVYDCN Sbjct: 721 DFVYDCN 727 >gi|19718769 engulfment and cell motility 2 [Homo sapiens] Length = 720 Score = 1114 bits (2881), Expect = 0.0 Identities = 548/725 (75%), Positives = 643/725 (88%), Gaps = 9/725 (1%) Query: 1 MPPPADIVKVAIEWPGAYPKLMEIDQKKPLSAIIKEVCDGWSLANHEYFALQHADSSNFY 60 MPPP+DIVKVAIEWPGA +L+EIDQK+PL++IIKEVCDGWSL N EY+ L++AD Y Sbjct: 1 MPPPSDIVKVAIEWPGANAQLLEIDQKRPLASIIKEVCDGWSLPNPEYYTLRYADGPQLY 60 Query: 61 ITEKNRNEIKNGTILRLTTSPAQNAQQLHERIQSSSMDAKLEALKDLASLSRDVTFAQEF 120 ITE+ R++IKNGTIL+L SP++ A+QL ER QSS+M+ +L+A+K+LA LS DVTFA EF Sbjct: 61 ITEQTRSDIKNGTILQLAISPSRAARQLMERTQSSNMETRLDAMKELAKLSADVTFATEF 120 Query: 121 INLDGISLLTQMVESGTERYQKLQKIMKPCFGDMLSFTLTAFVELMDHGIVSWDTFSVAF 180 IN+DGI +LT++VESGT+ + +ML+FTLTAF+ELMDHGIVSWD S+ F Sbjct: 121 INMDGIIVLTRLVESGTKLLSH--------YSEMLAFTLTAFLELMDHGIVSWDMVSITF 172 Query: 181 IKKIASFVNKSAIDISILQRSLAILESMVLNSHDLYQKVAQEITIGQLIPHLQGSDQEIQ 240 IK+IA +V++ +D+SILQRSLAILESMVLNS LYQK+A+EIT+GQLI HLQ S+QEIQ Sbjct: 173 IKQIAGYVSQPMVDVSILQRSLAILESMVLNSQSLYQKIAEEITVGQLISHLQVSNQEIQ 232 Query: 241 TYTIAVINALFLKAPDERRQEMANILAQKQLRSIILTHVIRAQRAINNEMAHQLYVLQVL 300 TY IA+INALFLKAP+++RQ+MAN AQK LRSIIL HVIR R I EMAHQLYVLQVL Sbjct: 233 TYAIALINALFLKAPEDKRQDMANAFAQKHLRSIILNHVIRGNRPIKTEMAHQLYVLQVL 292 Query: 301 TFNLLEDRMMTKMDPQDQAQRDIIFELRRIAFDAESEPNNSSGS-MEKRKSMYTRDYKKL 359 TFNLLE+RMMTKMDP DQAQRDIIFELRRIAFDAES+P+N+ GS EKRK+MYT+DYK L Sbjct: 293 TFNLLEERMMTKMDPNDQAQRDIIFELRRIAFDAESDPSNAPGSGTEKRKAMYTKDYKML 352 Query: 360 GFINHVNPAMDFTQTPPGMLALDNMLYFAKHHQDAYIRIVLENSSREDKHECPFGRSSIE 419 GF NH+NPAMDFTQTPPGMLALDNMLY AK HQD YIRIVLENSSREDKHECPFGRS+IE Sbjct: 353 GFTNHINPAMDFTQTPPGMLALDNMLYLAKVHQDTYIRIVLENSSREDKHECPFGRSAIE 412 Query: 420 LTKMLCEILKVGELPSETCNDFHPMFFTHDRSFEEFFCICIQLLNKTWKEMRATSEDFNK 479 LTKMLCEIL+VGELP+E ND+HPMFFTHDR+FEE F ICIQLLNKTWKEMRAT+EDFNK Sbjct: 413 LTKMLCEILQVGELPNEGRNDYHPMFFTHDRAFEELFGICIQLLNKTWKEMRATAEDFNK 472 Query: 480 VMQVVKEQVMRALTTKPSSLDQFKSKLQNLSYTEILKIRQSERMNQEDFQSRPILELKEK 539 VMQVV+EQ+ RAL +KP+SLDQFKSKL++LSY+EIL++RQSERM+Q+DFQS PI+EL+EK Sbjct: 473 VMQVVREQITRALPSKPNSLDQFKSKLRSLSYSEILRLRQSERMSQDDFQSPPIVELREK 532 Query: 540 IQPEILELIKQQRLNRLVEGTCFRKLNARRRQDKFWYCRLSPNHKVLHYGDLEESPQGEV 599 IQPEILELIKQQRLNRL EG+ FRK+ RRRQ++FWYCRL+ NHKVLHYGDL+++PQGEV Sbjct: 533 IQPEILELIKQQRLNRLCEGSSFRKIGNRRRQERFWYCRLALNHKVLHYGDLDDNPQGEV 592 Query: 600 PHDSLQDKLPVADIKAVVTGKDCPHMKEKGALKQNKEVLELAFSILYDSNCQLNFIAPDK 659 +SLQ+K+PVADIKA+VTGKDCPHMKEK ALKQNKEVLELAFSILYD + LNFIAP+K Sbjct: 593 TFESLQEKIPVADIKAIVTGKDCPHMKEKSALKQNKEVLELAFSILYDPDETLNFIAPNK 652 Query: 660 HEYCIWTDGLNALLGKDMMSDLTRNDLDTLLSMEIKLRLLDLENIQIPDAPPPIPKEPSN 719 +EYCIW DGL+ALLGKDM S+LT++DLDTLLSME+KLRLLDLENIQIP+APPPIPKEPS+ Sbjct: 653 YEYCIWIDGLSALLGKDMSSELTKSDLDTLLSMEMKLRLLDLENIQIPEAPPPIPKEPSS 712 Query: 720 YDFVY 724 YDFVY Sbjct: 713 YDFVY 717 >gi|33469947 engulfment and cell motility 2 [Homo sapiens] Length = 720 Score = 1114 bits (2881), Expect = 0.0 Identities = 548/725 (75%), Positives = 643/725 (88%), Gaps = 9/725 (1%) Query: 1 MPPPADIVKVAIEWPGAYPKLMEIDQKKPLSAIIKEVCDGWSLANHEYFALQHADSSNFY 60 MPPP+DIVKVAIEWPGA +L+EIDQK+PL++IIKEVCDGWSL N EY+ L++AD Y Sbjct: 1 MPPPSDIVKVAIEWPGANAQLLEIDQKRPLASIIKEVCDGWSLPNPEYYTLRYADGPQLY 60 Query: 61 ITEKNRNEIKNGTILRLTTSPAQNAQQLHERIQSSSMDAKLEALKDLASLSRDVTFAQEF 120 ITE+ R++IKNGTIL+L SP++ A+QL ER QSS+M+ +L+A+K+LA LS DVTFA EF Sbjct: 61 ITEQTRSDIKNGTILQLAISPSRAARQLMERTQSSNMETRLDAMKELAKLSADVTFATEF 120 Query: 121 INLDGISLLTQMVESGTERYQKLQKIMKPCFGDMLSFTLTAFVELMDHGIVSWDTFSVAF 180 IN+DGI +LT++VESGT+ + +ML+FTLTAF+ELMDHGIVSWD S+ F Sbjct: 121 INMDGIIVLTRLVESGTKLLSH--------YSEMLAFTLTAFLELMDHGIVSWDMVSITF 172 Query: 181 IKKIASFVNKSAIDISILQRSLAILESMVLNSHDLYQKVAQEITIGQLIPHLQGSDQEIQ 240 IK+IA +V++ +D+SILQRSLAILESMVLNS LYQK+A+EIT+GQLI HLQ S+QEIQ Sbjct: 173 IKQIAGYVSQPMVDVSILQRSLAILESMVLNSQSLYQKIAEEITVGQLISHLQVSNQEIQ 232 Query: 241 TYTIAVINALFLKAPDERRQEMANILAQKQLRSIILTHVIRAQRAINNEMAHQLYVLQVL 300 TY IA+INALFLKAP+++RQ+MAN AQK LRSIIL HVIR R I EMAHQLYVLQVL Sbjct: 233 TYAIALINALFLKAPEDKRQDMANAFAQKHLRSIILNHVIRGNRPIKTEMAHQLYVLQVL 292 Query: 301 TFNLLEDRMMTKMDPQDQAQRDIIFELRRIAFDAESEPNNSSGS-MEKRKSMYTRDYKKL 359 TFNLLE+RMMTKMDP DQAQRDIIFELRRIAFDAES+P+N+ GS EKRK+MYT+DYK L Sbjct: 293 TFNLLEERMMTKMDPNDQAQRDIIFELRRIAFDAESDPSNAPGSGTEKRKAMYTKDYKML 352 Query: 360 GFINHVNPAMDFTQTPPGMLALDNMLYFAKHHQDAYIRIVLENSSREDKHECPFGRSSIE 419 GF NH+NPAMDFTQTPPGMLALDNMLY AK HQD YIRIVLENSSREDKHECPFGRS+IE Sbjct: 353 GFTNHINPAMDFTQTPPGMLALDNMLYLAKVHQDTYIRIVLENSSREDKHECPFGRSAIE 412 Query: 420 LTKMLCEILKVGELPSETCNDFHPMFFTHDRSFEEFFCICIQLLNKTWKEMRATSEDFNK 479 LTKMLCEIL+VGELP+E ND+HPMFFTHDR+FEE F ICIQLLNKTWKEMRAT+EDFNK Sbjct: 413 LTKMLCEILQVGELPNEGRNDYHPMFFTHDRAFEELFGICIQLLNKTWKEMRATAEDFNK 472 Query: 480 VMQVVKEQVMRALTTKPSSLDQFKSKLQNLSYTEILKIRQSERMNQEDFQSRPILELKEK 539 VMQVV+EQ+ RAL +KP+SLDQFKSKL++LSY+EIL++RQSERM+Q+DFQS PI+EL+EK Sbjct: 473 VMQVVREQITRALPSKPNSLDQFKSKLRSLSYSEILRLRQSERMSQDDFQSPPIVELREK 532 Query: 540 IQPEILELIKQQRLNRLVEGTCFRKLNARRRQDKFWYCRLSPNHKVLHYGDLEESPQGEV 599 IQPEILELIKQQRLNRL EG+ FRK+ RRRQ++FWYCRL+ NHKVLHYGDL+++PQGEV Sbjct: 533 IQPEILELIKQQRLNRLCEGSSFRKIGNRRRQERFWYCRLALNHKVLHYGDLDDNPQGEV 592 Query: 600 PHDSLQDKLPVADIKAVVTGKDCPHMKEKGALKQNKEVLELAFSILYDSNCQLNFIAPDK 659 +SLQ+K+PVADIKA+VTGKDCPHMKEK ALKQNKEVLELAFSILYD + LNFIAP+K Sbjct: 593 TFESLQEKIPVADIKAIVTGKDCPHMKEKSALKQNKEVLELAFSILYDPDETLNFIAPNK 652 Query: 660 HEYCIWTDGLNALLGKDMMSDLTRNDLDTLLSMEIKLRLLDLENIQIPDAPPPIPKEPSN 719 +EYCIW DGL+ALLGKDM S+LT++DLDTLLSME+KLRLLDLENIQIP+APPPIPKEPS+ Sbjct: 653 YEYCIWIDGLSALLGKDMSSELTKSDLDTLLSMEMKLRLLDLENIQIPEAPPPIPKEPSS 712 Query: 720 YDFVY 724 YDFVY Sbjct: 713 YDFVY 717 >gi|87298935 engulfment and cell motility 3 [Homo sapiens] Length = 773 Score = 750 bits (1937), Expect = 0.0 Identities = 376/730 (51%), Positives = 524/730 (71%), Gaps = 17/730 (2%) Query: 1 MPPPADIVKVAIEWPGAYPKLMEIDQKKPLSAIIKEVCDGWSLANHEYFALQHADSSNFY 60 M PP ++VK+AI+ A P+L+++DQ KPL+A++KEVCD WSL + E +ALQ AD Y Sbjct: 54 MAPPRNVVKIAIKMRDAIPQLIQLDQAKPLAAVLKEVCDAWSLTHSERYALQFADGHRRY 113 Query: 61 ITEKNRNEIKNGTILRLTTSPAQNAQQLHERIQSSSMDAKLEALKDLASLSRDVTFAQEF 120 ITE NR EIKNG+IL L+T+P A+QL +QS+S + + EAL+ L L+ D+ FA+E Sbjct: 114 ITENNRAEIKNGSILCLSTAPDLEAEQLLGGLQSNSPEGRREALRRLVPLASDMIFAREV 173 Query: 121 INLDGISLLTQMVESGTERYQKLQKIMKPCFGDMLSFTLTAFVELMDHGIVSWDTFSVAF 180 I+ +G+ +L ++E G + G++L+ +L AF ELM+HG+VSW+T S+ F Sbjct: 174 ISRNGLQILGTIIEDGDD------------LGEVLALSLRAFSELMEHGVVSWETLSIPF 221 Query: 181 IKKIASFVNKSAIDISILQRSLAILESMVLNSHDLYQKVAQEITIGQLIPHLQGSDQEIQ 240 ++K+ +VN + +D S+ +L +LES+ L+S L Q V E+ + +L+ HLQ +Q++Q Sbjct: 222 VRKVVCYVNMNLMDASVPPLALGLLESVTLSSPALGQLVKSEVPLDRLLVHLQVMNQQLQ 281 Query: 241 TYTIAVINALFLKAPDERRQEMANILAQKQLRSIILTHVIRAQRAINNEMAHQLYVLQVL 300 T +A++ AL A R+ M + L Q+ LR I ++I + + +EMAH LYVLQ L Sbjct: 282 TKAMALLTALLQGASPVERKHMLDYLWQRNLRQFIYKNIIHSAAPMGDEMAHHLYVLQAL 341 Query: 301 TFNLLEDRMMTKMDPQDQAQRDIIFELRRIAFDAESEPNNSSGSMEKRKSMYTRDYKKLG 360 LLE RM T +DP Q QR+ + LR+ AF+ E E + + S ++R+S+ R+++KLG Sbjct: 342 MLGLLEPRMRTPLDPYSQEQREQLQVLRQAAFEVEGESSGAGLSADRRRSLCAREFRKLG 401 Query: 361 FINHVNPAMDFTQTPPGMLALDNMLYFAKHHQDAYIRIVLENSSREDKHECPFGRSSIEL 420 F N NPA D + PPG+LALDNMLYF+++ AY R VLENSSREDKHECPF R SI+L Sbjct: 402 FSNS-NPAQDLERVPPGLLALDNMLYFSRNAPSAYSRFVLENSSREDKHECPFARGSIQL 460 Query: 421 TKMLCEILKVGELPSETCNDFHPMFFTHDRSFEEFFCICIQLLNKTWKEMRATSEDFNKV 480 T +LCE+L+VGE SET DF PMFF D+SF E FC+ IQLLNKTWKEMRAT EDF+KV Sbjct: 461 TVLLCELLRVGEPCSETAQDFSPMFFGQDQSFHELFCVGIQLLNKTWKEMRATQEDFDKV 520 Query: 481 MQVVKEQVMRALTTKPSSLDQFKSKLQNLSYTEILKIRQSERMNQEDFQSRPILELKEKI 540 MQVV+EQ+ R L KP+SL+ F++K+ L+Y E+L++RQ+ER++QE + PILEL+EK+ Sbjct: 521 MQVVREQLARTLALKPTSLELFRTKVNALTYGEVLRLRQTERLHQEGTLAPPILELREKL 580 Query: 541 QPEILELIKQQRLNRLVEGTCFRKLNARRRQDKFWYCRLSPNHKVLHYGDLEESPQGEVP 600 +PE++ LI+QQRL RL EGT FRK+++RRRQDK W+C LSPNHK+L YGD+EE Sbjct: 581 KPELMGLIRQQRLLRLCEGTLFRKISSRRRQDKLWFCCLSPNHKLLQYGDMEEGASPPT- 639 Query: 601 HDSLQDKLPVADIKAVVTGKDCPHMKEKGALKQNKEVLELAFSILYD---SNCQLNFIAP 657 +SL ++LPVAD++A++TGKDCPH++EKG+ KQNK++ ELAFSI YD LNFIAP Sbjct: 640 LESLPEQLPVADMRALLTGKDCPHVREKGSGKQNKDLYELAFSISYDRGEEEAYLNFIAP 699 Query: 658 DKHEYCIWTDGLNALLGKDMMSDLTRNDLDTLLSMEIKLRLLDLENIQIPDAPPPIPKEP 717 K E+ +WTDGL+ALLG M S+ TR DL+ LL+ME KLRLL+LEN+ IP+ PPP+P P Sbjct: 700 SKREFYLWTDGLSALLGSPMGSEQTRLDLEQLLTMETKLRLLELENVPIPERPPPVPPPP 759 Query: 718 SNYDFVYDCN 727 +N++F YDC+ Sbjct: 760 TNFNFCYDCS 769 >gi|86788140 engulfment and cell motility 1 isoform 2 [Homo sapiens] Length = 247 Score = 503 bits (1295), Expect = e-142 Identities = 247/247 (100%), Positives = 247/247 (100%) Query: 481 MQVVKEQVMRALTTKPSSLDQFKSKLQNLSYTEILKIRQSERMNQEDFQSRPILELKEKI 540 MQVVKEQVMRALTTKPSSLDQFKSKLQNLSYTEILKIRQSERMNQEDFQSRPILELKEKI Sbjct: 1 MQVVKEQVMRALTTKPSSLDQFKSKLQNLSYTEILKIRQSERMNQEDFQSRPILELKEKI 60 Query: 541 QPEILELIKQQRLNRLVEGTCFRKLNARRRQDKFWYCRLSPNHKVLHYGDLEESPQGEVP 600 QPEILELIKQQRLNRLVEGTCFRKLNARRRQDKFWYCRLSPNHKVLHYGDLEESPQGEVP Sbjct: 61 QPEILELIKQQRLNRLVEGTCFRKLNARRRQDKFWYCRLSPNHKVLHYGDLEESPQGEVP 120 Query: 601 HDSLQDKLPVADIKAVVTGKDCPHMKEKGALKQNKEVLELAFSILYDSNCQLNFIAPDKH 660 HDSLQDKLPVADIKAVVTGKDCPHMKEKGALKQNKEVLELAFSILYDSNCQLNFIAPDKH Sbjct: 121 HDSLQDKLPVADIKAVVTGKDCPHMKEKGALKQNKEVLELAFSILYDSNCQLNFIAPDKH 180 Query: 661 EYCIWTDGLNALLGKDMMSDLTRNDLDTLLSMEIKLRLLDLENIQIPDAPPPIPKEPSNY 720 EYCIWTDGLNALLGKDMMSDLTRNDLDTLLSMEIKLRLLDLENIQIPDAPPPIPKEPSNY Sbjct: 181 EYCIWTDGLNALLGKDMMSDLTRNDLDTLLSMEIKLRLLDLENIQIPDAPPPIPKEPSNY 240 Query: 721 DFVYDCN 727 DFVYDCN Sbjct: 241 DFVYDCN 247 >gi|18765702 engulfment and cell motility 1 isoform 2 [Homo sapiens] Length = 247 Score = 503 bits (1295), Expect = e-142 Identities = 247/247 (100%), Positives = 247/247 (100%) Query: 481 MQVVKEQVMRALTTKPSSLDQFKSKLQNLSYTEILKIRQSERMNQEDFQSRPILELKEKI 540 MQVVKEQVMRALTTKPSSLDQFKSKLQNLSYTEILKIRQSERMNQEDFQSRPILELKEKI Sbjct: 1 MQVVKEQVMRALTTKPSSLDQFKSKLQNLSYTEILKIRQSERMNQEDFQSRPILELKEKI 60 Query: 541 QPEILELIKQQRLNRLVEGTCFRKLNARRRQDKFWYCRLSPNHKVLHYGDLEESPQGEVP 600 QPEILELIKQQRLNRLVEGTCFRKLNARRRQDKFWYCRLSPNHKVLHYGDLEESPQGEVP Sbjct: 61 QPEILELIKQQRLNRLVEGTCFRKLNARRRQDKFWYCRLSPNHKVLHYGDLEESPQGEVP 120 Query: 601 HDSLQDKLPVADIKAVVTGKDCPHMKEKGALKQNKEVLELAFSILYDSNCQLNFIAPDKH 660 HDSLQDKLPVADIKAVVTGKDCPHMKEKGALKQNKEVLELAFSILYDSNCQLNFIAPDKH Sbjct: 121 HDSLQDKLPVADIKAVVTGKDCPHMKEKGALKQNKEVLELAFSILYDSNCQLNFIAPDKH 180 Query: 661 EYCIWTDGLNALLGKDMMSDLTRNDLDTLLSMEIKLRLLDLENIQIPDAPPPIPKEPSNY 720 EYCIWTDGLNALLGKDMMSDLTRNDLDTLLSMEIKLRLLDLENIQIPDAPPPIPKEPSNY Sbjct: 181 EYCIWTDGLNALLGKDMMSDLTRNDLDTLLSMEIKLRLLDLENIQIPDAPPPIPKEPSNY 240 Query: 721 DFVYDCN 727 DFVYDCN Sbjct: 241 DFVYDCN 247 >gi|118918407 spectrin repeat containing, nuclear envelope 2 isoform 5 [Homo sapiens] Length = 6907 Score = 38.5 bits (88), Expect = 0.022 Identities = 67/378 (17%), Positives = 149/378 (39%), Gaps = 52/378 (13%) Query: 181 IKKIASFVNKSAIDISILQRSLAILESMVLNSHDLYQKVAQEITIG------QLIPHLQG 234 ++K+ N+ ++ L++ LA+ +S+ N+ + QK+ ++ L L Sbjct: 2289 LQKLQELENRLSLQDGTLKKILALAKSVKQNTSSVGQKIIKDDIKSLQCKQKDLENRLAS 2348 Query: 235 SDQEIQTYTIAVINALFLKAPDER--------RQEMANILAQKQLRSIILTHVIRAQRAI 286 + QE++ +++ + K E+ R++ A Q+ + + I Sbjct: 2349 AKQEMECCLNSILKS---KRSTEKKGKFTLPGREKQATSDVQESTQESAAVEKLEEDWEI 2405 Query: 287 NNEMAHQLYVLQVLTFNLLEDRMMTKMDPQDQAQRDIIFELRRIAFDAESEPNNSSGSME 346 N + A ++ + + L+ N E T+ + + + EL+ + ++ N +E Sbjct: 2406 NKDSAVEMAMSKQLSLNAQESMKNTEDERK-------VNELQNQPLELDTMLRNEQ--LE 2456 Query: 347 KRKSMYTRDYKKLGFINHVNPAMDFTQTPPGMLALDNMLYFAKHHQDAYIRIVLENSSRE 406 + + +YT+ K I + +T G L L N+ Y A+H + ++ ++E Sbjct: 2457 EIEKLYTQLEAKKAAIKPLEQTECLNKTETGALVLHNIGYSAQHLDNLLQALITLKKNKE 2516 Query: 407 DKHECPFG---------RSSIELTKMLCEILKVGELPSETCNDFHPMFFTHDRSFEEFFC 457 ++ C SS++ E LKVG L S T D F ++ Sbjct: 2517 SQY-CVLRDFQEYLAAVESSMKALLTDKESLKVGPLDSVTYLDKIKKFIASIEKEKD--- 2572 Query: 458 ICIQLLNKTWKEMRATSEDFNKVM------------QVVKEQVMRALTTKPSSLDQFKSK 505 + L W+ + D +K + + V++Q+ + + + D+F + Sbjct: 2573 -SLGNLKIKWENLSNHVTDMDKKLLESQIKQLEHGWEQVEQQIQKKYSQQVVEYDEFTTL 2631 Query: 506 LQNLSYTEILKIRQSERM 523 + + TEI +Q + + Sbjct: 2632 MNKVQDTEISLQQQQQHL 2649 Score = 33.5 bits (75), Expect = 0.72 Identities = 23/91 (25%), Positives = 42/91 (46%), Gaps = 2/91 (2%) Query: 461 QLLNKTWKEMRATSEDFNKVMQVVKEQVMRALTTKPSSLDQFKSKLQ--NLSYTEILKIR 518 + L+ K ++ E ++Q + K SS + + LQ NLS E + Sbjct: 4313 EALSLKLKTVKCNLEKVQMMLQEKHSEDQHPTILKKSSEPEHQEALQPVNLSELESIVTE 4372 Query: 519 QSERMNQEDFQSRPILELKEKIQPEILELIK 549 + + Q+DFQ + +LELK Q + ++ I+ Sbjct: 4373 RPQFSRQKDFQQQQVLELKPMEQKDFIKFIE 4403 >gi|118918403 spectrin repeat containing, nuclear envelope 2 isoform 1 [Homo sapiens] Length = 6885 Score = 38.5 bits (88), Expect = 0.022 Identities = 67/378 (17%), Positives = 149/378 (39%), Gaps = 52/378 (13%) Query: 181 IKKIASFVNKSAIDISILQRSLAILESMVLNSHDLYQKVAQEITIG------QLIPHLQG 234 ++K+ N+ ++ L++ LA+ +S+ N+ + QK+ ++ L L Sbjct: 2289 LQKLQELENRLSLQDGTLKKILALAKSVKQNTSSVGQKIIKDDIKSLQCKQKDLENRLAS 2348 Query: 235 SDQEIQTYTIAVINALFLKAPDER--------RQEMANILAQKQLRSIILTHVIRAQRAI 286 + QE++ +++ + K E+ R++ A Q+ + + I Sbjct: 2349 AKQEMECCLNSILKS---KRSTEKKGKFTLPGREKQATSDVQESTQESAAVEKLEEDWEI 2405 Query: 287 NNEMAHQLYVLQVLTFNLLEDRMMTKMDPQDQAQRDIIFELRRIAFDAESEPNNSSGSME 346 N + A ++ + + L+ N E T+ + + + EL+ + ++ N +E Sbjct: 2406 NKDSAVEMAMSKQLSLNAQESMKNTEDERK-------VNELQNQPLELDTMLRNEQ--LE 2456 Query: 347 KRKSMYTRDYKKLGFINHVNPAMDFTQTPPGMLALDNMLYFAKHHQDAYIRIVLENSSRE 406 + + +YT+ K I + +T G L L N+ Y A+H + ++ ++E Sbjct: 2457 EIEKLYTQLEAKKAAIKPLEQTECLNKTETGALVLHNIGYSAQHLDNLLQALITLKKNKE 2516 Query: 407 DKHECPFG---------RSSIELTKMLCEILKVGELPSETCNDFHPMFFTHDRSFEEFFC 457 ++ C SS++ E LKVG L S T D F ++ Sbjct: 2517 SQY-CVLRDFQEYLAAVESSMKALLTDKESLKVGPLDSVTYLDKIKKFIASIEKEKD--- 2572 Query: 458 ICIQLLNKTWKEMRATSEDFNKVM------------QVVKEQVMRALTTKPSSLDQFKSK 505 + L W+ + D +K + + V++Q+ + + + D+F + Sbjct: 2573 -SLGNLKIKWENLSNHVTDMDKKLLESQIKQLEHGWEQVEQQIQKKYSQQVVEYDEFTTL 2631 Query: 506 LQNLSYTEILKIRQSERM 523 + + TEI +Q + + Sbjct: 2632 MNKVQDTEISLQQQQQHL 2649 Score = 33.5 bits (75), Expect = 0.72 Identities = 23/91 (25%), Positives = 42/91 (46%), Gaps = 2/91 (2%) Query: 461 QLLNKTWKEMRATSEDFNKVMQVVKEQVMRALTTKPSSLDQFKSKLQ--NLSYTEILKIR 518 + L+ K ++ E ++Q + K SS + + LQ NLS E + Sbjct: 4313 EALSLKLKTVKCNLEKVQMMLQEKHSEDQHPTILKKSSEPEHQEALQPVNLSELESIVTE 4372 Query: 519 QSERMNQEDFQSRPILELKEKIQPEILELIK 549 + + Q+DFQ + +LELK Q + ++ I+ Sbjct: 4373 RPQFSRQKDFQQQQVLELKPMEQKDFIKFIE 4403 >gi|118572599 formin homology 2 domain containing 1 [Homo sapiens] Length = 1164 Score = 35.4 bits (80), Expect = 0.19 Identities = 43/212 (20%), Positives = 87/212 (41%), Gaps = 14/212 (6%) Query: 74 ILRLTTSPAQNAQQLHERIQSSSMDAKLEALKDLASL-SRDVTFAQEFINLDGISLLTQM 132 ILR S NA + E++ SSS +L L + D EF++ +G+S L ++ Sbjct: 111 ILRTQLSVRVNA--ILEKLYSSSGPELRRSLFSLKQIFQEDKDLVPEFVHSEGLSCLIRV 168 Query: 133 VESGTERYQKLQKIMKPCFGDMLSFTLTAFVELMDHGIVSWDTFSVAFIKKIASFVNKSA 192 + YQ + G ++ F + + W A + ++ V K+A Sbjct: 169 GAAADHNYQSY---ILRALGQLMLFVDGMLGVVAHSDTIQWLYTLCASLSRL---VVKTA 222 Query: 193 IDISIL----QRSLAILESMVLNSHDLYQKVAQEITIGQLIPHLQGSDQEIQTYTIAVIN 248 + + ++ + A L +NS + ++ G+D E+ YT+ +IN Sbjct: 223 LKLLLVFVEYSENNAPLFIRAVNSVASTTGAPPWANLVSILEEKNGADPELLVYTVTLIN 282 Query: 249 ALFLKAPDERR-QEMANILAQKQLRSIILTHV 279 PD+ ++ + L Q+ + +++ H+ Sbjct: 283 KTLAALPDQDSFYDVTDALEQQGMEALVQRHL 314 >gi|110349756 zygin 2 isoform 2 [Homo sapiens] Length = 380 Score = 33.1 bits (74), Expect = 0.94 Identities = 22/108 (20%), Positives = 57/108 (52%), Gaps = 4/108 (3%) Query: 305 LEDRMMTKMDPQDQAQRDIIFELRRIAFDAESEPNNSSGSMEKR-KSMYTRDYKKLGFIN 363 +E+ M DP+D L ++ + ++ +S+GS E+R K + + ++ + Sbjct: 169 IEEMMQESPDPEDDETPTQSDRLSMLSQEIQTLKRSSTGSYEERVKRLSVSELNEI--LE 226 Query: 364 HVNPAM-DFTQTPPGMLALDNMLYFAKHHQDAYIRIVLENSSREDKHE 410 + A+ ++++ LAL + L F K ++++I +++E +++ +H+ Sbjct: 227 EIETAIKEYSEELVQQLALRDELEFEKEVKNSFISVLIEVQNKQKEHK 274 >gi|110349754 zygin 2 isoform 1 [Homo sapiens] Length = 353 Score = 33.1 bits (74), Expect = 0.94 Identities = 22/108 (20%), Positives = 57/108 (52%), Gaps = 4/108 (3%) Query: 305 LEDRMMTKMDPQDQAQRDIIFELRRIAFDAESEPNNSSGSMEKR-KSMYTRDYKKLGFIN 363 +E+ M DP+D L ++ + ++ +S+GS E+R K + + ++ + Sbjct: 169 IEEMMQESPDPEDDETPTQSDRLSMLSQEIQTLKRSSTGSYEERVKRLSVSELNEI--LE 226 Query: 364 HVNPAM-DFTQTPPGMLALDNMLYFAKHHQDAYIRIVLENSSREDKHE 410 + A+ ++++ LAL + L F K ++++I +++E +++ +H+ Sbjct: 227 EIETAIKEYSEELVQQLALRDELEFEKEVKNSFISVLIEVQNKQKEHK 274 >gi|187761324 shootin1 isoform a [Homo sapiens] Length = 631 Score = 32.7 bits (73), Expect = 1.2 Identities = 58/271 (21%), Positives = 110/271 (40%), Gaps = 51/271 (18%) Query: 457 CICIQLLNKTWKEMRATSEDFNKVMQVVKEQVMRALTTKPSSLDQFKSKLQNLSYTEILK 516 C+ +Q K KE+R ++++ V +E+ + A+ L+ KSKL + E+ K Sbjct: 135 CVSVQC-QKQIKELR------DQIVSVQEEKKILAI-----ELENLKSKLVEV-IEEVNK 181 Query: 517 IRQSER-MNQEDFQSRPILELKEKIQPEILELIKQQRLNRLVEGTCFRKLNARRRQDKFW 575 ++Q + +N E + R +LE ++ +E ++ ++N +E RK Q+ F Sbjct: 182 VKQEKTVLNSEVLEQRKVLEKCNRVSMLAVEEYEEMQVNLELEKD-LRKKAESFAQEMF- 239 Query: 576 YCRLSPNHKVLHYGDLEESPQGEVPHDSLQDKLPVADI-KAVVTGKDCPHMKEKGALKQN 634 +E++ H LQ +P + KA+ E+ ++ Sbjct: 240 ---------------IEQNKLKRQSHLLLQSSIPDQQLLKALDENAKLTQQLEEERIQHQ 284 Query: 635 KEVLELAFSI--------LYDSNCQLNFIAPDKHEYCIWTDGLNALLGKDMMSDLTRNDL 686 ++V EL + +++ QL + DK E + K S+ +L Sbjct: 285 QKVKELEEQLENETLHKEIHNLKQQLELLEEDKKELEL----------KYQNSEEKARNL 334 Query: 687 DTLLSMEIKLRLLDLENIQIPDAPPPIPKEP 717 + E++ R+ EN P PPP P P Sbjct: 335 KHSVD-ELQKRVNQSENSVPPPPPPPPPLPP 364 >gi|50511340 shootin1 isoform b [Homo sapiens] Length = 456 Score = 32.7 bits (73), Expect = 1.2 Identities = 58/271 (21%), Positives = 110/271 (40%), Gaps = 51/271 (18%) Query: 457 CICIQLLNKTWKEMRATSEDFNKVMQVVKEQVMRALTTKPSSLDQFKSKLQNLSYTEILK 516 C+ +Q K KE+R ++++ V +E+ + A+ L+ KSKL + E+ K Sbjct: 135 CVSVQC-QKQIKELR------DQIVSVQEEKKILAI-----ELENLKSKLVEV-IEEVNK 181 Query: 517 IRQSER-MNQEDFQSRPILELKEKIQPEILELIKQQRLNRLVEGTCFRKLNARRRQDKFW 575 ++Q + +N E + R +LE ++ +E ++ ++N +E RK Q+ F Sbjct: 182 VKQEKTVLNSEVLEQRKVLEKCNRVSMLAVEEYEEMQVNLELEKD-LRKKAESFAQEMF- 239 Query: 576 YCRLSPNHKVLHYGDLEESPQGEVPHDSLQDKLPVADI-KAVVTGKDCPHMKEKGALKQN 634 +E++ H LQ +P + KA+ E+ ++ Sbjct: 240 ---------------IEQNKLKRQSHLLLQSSIPDQQLLKALDENAKLTQQLEEERIQHQ 284 Query: 635 KEVLELAFSI--------LYDSNCQLNFIAPDKHEYCIWTDGLNALLGKDMMSDLTRNDL 686 ++V EL + +++ QL + DK E + K S+ +L Sbjct: 285 QKVKELEEQLENETLHKEIHNLKQQLELLEEDKKELEL----------KYQNSEEKARNL 334 Query: 687 DTLLSMEIKLRLLDLENIQIPDAPPPIPKEP 717 + E++ R+ EN P PPP P P Sbjct: 335 KHSVD-ELQKRVNQSENSVPPPPPPPPPLPP 364 >gi|169208122 PREDICTED: hypothetical protein isoform 1 [Homo sapiens] Length = 479 Score = 32.3 bits (72), Expect = 1.6 Identities = 33/125 (26%), Positives = 59/125 (47%), Gaps = 8/125 (6%) Query: 453 EEFFCICIQLLNKTWKEMRATSEDFNKVMQVVKEQVMRALTTKPSSLDQFKSKLQNLSYT 512 EE C + L + + +R E ++ + + EQ R + +Q K Q Sbjct: 226 EERLCEQEERLREQEERLREQEERLHEQEERLCEQEERLCEQEERLCEQEKLPGQERLLE 285 Query: 513 EILKIRQSERMNQEDFQSRPILELKEKIQPEILELIKQQRL----NRLVEGTCFRKLNAR 568 E+ K+ + ER +E Q R +LE +E++ E+ EL++Q+RL RL + R+L Sbjct: 286 EVEKLLEQERRQEE--QER-LLE-RERLLDEVEELLEQERLRQQDERLWQQETLRELERL 341 Query: 569 RRQDK 573 R ++ Sbjct: 342 RELER 346 >gi|55770834 centromere protein F [Homo sapiens] Length = 3114 Score = 31.6 bits (70), Expect = 2.7 Identities = 37/175 (21%), Positives = 71/175 (40%), Gaps = 9/175 (5%) Query: 465 KTWKEMRATSEDFNKVMQVVKEQVMRALTTKPSSLDQFKSKLQNLSYTEILKIRQSERMN 524 +T + + ED + VV E + AL K L K++ EI ++++S + Sbjct: 880 ETSQRISKLQEDTSAHQNVVAE-TLSALENKEKELQLLNDKVET-EQAEIQELKKSNHLL 937 Query: 525 QEDFQSRPILE----LKEKIQPEILELIKQQRLNRLVEGTCFRKLNARRRQDKFWYCRLS 580 ++ + +L L++K I+ L K++ E +++NA Q+K + Sbjct: 938 EDSLKELQLLSETLSLEKKEMSSIISLNKREIEELTQENGTLKEINASLNQEKM--NLIQ 995 Query: 581 PNHKVLHYGDLEESPQGEVPHDSLQDKLPVADIKAVVTGKDCPHMKEKGALKQNK 635 + +Y D E E+ Q+KL + + TG + +K Q K Sbjct: 996 KSESFANYIDEREKSISELSDQYKQEKLILLQ-RCEETGNAYEDLSQKYKAAQEK 1049 >gi|237858679 neurofascin isoform 3 precursor [Homo sapiens] Length = 1174 Score = 31.2 bits (69), Expect = 3.6 Identities = 33/138 (23%), Positives = 56/138 (40%), Gaps = 28/138 (20%) Query: 366 NPAMDFTQTPPGMLALDNMLYFAKHHQDAYIRIVLENSSREDKHECPFGRSSIELTKMLC 425 N + PP ML+ N L IR++L N +R D CPF S I + Sbjct: 431 NAFVSVLDVPPRMLSPRNQL----------IRVILYNRTRLD---CPFFGSPIPTLRWF- 476 Query: 426 EILKVGELPSETCNDFH---------PMFFTHDRSFEEFFCICIQLLNKTWKEMRATSED 476 K G+ + ++H M D+ + C+ +L K ++R +D Sbjct: 477 ---KNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGI--YTCVATNILGKAENQVRLEVKD 531 Query: 477 FNKVMQVVKEQVMRALTT 494 ++ ++ ++QV R TT Sbjct: 532 PTRIYRMPEDQVARRGTT 549 >gi|237858677 neurofascin isoform 2 precursor [Homo sapiens] Length = 1189 Score = 31.2 bits (69), Expect = 3.6 Identities = 33/138 (23%), Positives = 56/138 (40%), Gaps = 28/138 (20%) Query: 366 NPAMDFTQTPPGMLALDNMLYFAKHHQDAYIRIVLENSSREDKHECPFGRSSIELTKMLC 425 N + PP ML+ N L IR++L N +R D CPF S I + Sbjct: 431 NAFVSVLDVPPRMLSPRNQL----------IRVILYNRTRLD---CPFFGSPIPTLRWF- 476 Query: 426 EILKVGELPSETCNDFH---------PMFFTHDRSFEEFFCICIQLLNKTWKEMRATSED 476 K G+ + ++H M D+ + C+ +L K ++R +D Sbjct: 477 ---KNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGI--YTCVATNILGKAENQVRLEVKD 531 Query: 477 FNKVMQVVKEQVMRALTT 494 ++ ++ ++QV R TT Sbjct: 532 PTRIYRMPEDQVARRGTT 549 >gi|89903008 neurofascin isoform 4 precursor [Homo sapiens] Length = 1169 Score = 31.2 bits (69), Expect = 3.6 Identities = 33/138 (23%), Positives = 56/138 (40%), Gaps = 28/138 (20%) Query: 366 NPAMDFTQTPPGMLALDNMLYFAKHHQDAYIRIVLENSSREDKHECPFGRSSIELTKMLC 425 N + PP ML+ N L IR++L N +R D CPF S I + Sbjct: 431 NAFVSVLDVPPRMLSPRNQL----------IRVILYNRTRLD---CPFFGSPIPTLRWF- 476 Query: 426 EILKVGELPSETCNDFH---------PMFFTHDRSFEEFFCICIQLLNKTWKEMRATSED 476 K G+ + ++H M D+ + C+ +L K ++R +D Sbjct: 477 ---KNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGI--YTCVATNILGKAENQVRLEVKD 531 Query: 477 FNKVMQVVKEQVMRALTT 494 ++ ++ ++QV R TT Sbjct: 532 PTRIYRMPEDQVARRGTT 549 >gi|222537750 ankyrin repeat domain 30B [Homo sapiens] Length = 1392 Score = 31.2 bits (69), Expect = 3.6 Identities = 47/192 (24%), Positives = 89/192 (46%), Gaps = 26/192 (13%) Query: 461 QLLNKTWKEMRATSEDFNKVMQVVKEQVMRALTTKPSSLDQFKSKLQNLSYTEILKIRQS 520 +L +++ A E V+++++ A K S L+ K+K + E+ +R + Sbjct: 961 ELKKDNCEQITAKMEQTKNKFCVLQKELSEAKEIK-SQLENQKAKWEQ----ELCSVRLT 1015 Query: 521 ERMNQEDFQSRPILELKEKIQPEILELIKQQRLNRLVEGTCFRKLNARRRQDKFWYCRLS 580 +NQE+ + R + LKEKI+PE +L K+ + + +E T R QD S Sbjct: 1016 --LNQEEEKRRNVDILKEKIRPE-EQLRKKLEVKQQLEQTL-------RIQDIELKSVTS 1065 Query: 581 PNHKVLHYGDLEESPQGEVPHDSLQDKLPVADIKAVVTGKDCPHMKEKGALKQNKEVLEL 640 ++V H + E ++ H++ K +A +K V +K + +K+NK ++ Sbjct: 1066 NLNQVSHTHESE----NDLFHENCMLKKEIAMLKLEVA-----TLKHQHQVKENKYFEDI 1116 Query: 641 AFSILYDSNCQL 652 IL + N +L Sbjct: 1117 --KILQEKNAEL 1126 >gi|192807309 TNFAIP3 interacting protein 3 [Homo sapiens] Length = 325 Score = 31.2 bits (69), Expect = 3.6 Identities = 43/208 (20%), Positives = 88/208 (42%), Gaps = 21/208 (10%) Query: 460 IQLLNKTWKEMRATSEDFNKVMQVVKEQVMRALTTKPSSLDQFKSKLQNLSYTEILKIRQ 519 I+ L K KE+ ++ +++ + +KE R + + LD + L + R+ Sbjct: 40 IRCLEKQRKELLEVNQQWDQQFRSMKELYERKVAELKTKLDAAERFLSTREKDPHQRQRK 99 Query: 520 SERMNQEDFQ---SRPILELKEKIQPEI-LELIKQQRLNRLVEGTCFRKLNARRRQDKFW 575 +R ++D Q +R L+ +EK + + EL + + N+L++G K ++ + + Sbjct: 100 DDRQREDDRQRDLTRDRLQREEKEKERLNEELHELKEENKLLKG----KNTLANKEKEHY 155 Query: 576 YCRLSPNHKVLHYG---------DLEESPQGEVPHDSLQDKLPVADIKAVVTGKDC-PHM 625 C + +K L D + E H+ ++ ++ V + + +D Sbjct: 156 ECEIKRLNKALQDALNIKCSFSEDCLRKSRVEFCHEEMRTEMEVLKQQVQIYEEDFKKER 215 Query: 626 KEKGALKQNKEVLELAFSILYDSNCQLN 653 ++ L Q KE L+ I S QLN Sbjct: 216 SDRERLNQEKEELQ---QINETSQSQLN 240 >gi|192807305 TNFAIP3 interacting protein 3 [Homo sapiens] Length = 325 Score = 31.2 bits (69), Expect = 3.6 Identities = 43/208 (20%), Positives = 88/208 (42%), Gaps = 21/208 (10%) Query: 460 IQLLNKTWKEMRATSEDFNKVMQVVKEQVMRALTTKPSSLDQFKSKLQNLSYTEILKIRQ 519 I+ L K KE+ ++ +++ + +KE R + + LD + L + R+ Sbjct: 40 IRCLEKQRKELLEVNQQWDQQFRSMKELYERKVAELKTKLDAAERFLSTREKDPHQRQRK 99 Query: 520 SERMNQEDFQ---SRPILELKEKIQPEI-LELIKQQRLNRLVEGTCFRKLNARRRQDKFW 575 +R ++D Q +R L+ +EK + + EL + + N+L++G K ++ + + Sbjct: 100 DDRQREDDRQRDLTRDRLQREEKEKERLNEELHELKEENKLLKG----KNTLANKEKEHY 155 Query: 576 YCRLSPNHKVLHYG---------DLEESPQGEVPHDSLQDKLPVADIKAVVTGKDC-PHM 625 C + +K L D + E H+ ++ ++ V + + +D Sbjct: 156 ECEIKRLNKALQDALNIKCSFSEDCLRKSRVEFCHEEMRTEMEVLKQQVQIYEEDFKKER 215 Query: 626 KEKGALKQNKEVLELAFSILYDSNCQLN 653 ++ L Q KE L+ I S QLN Sbjct: 216 SDRERLNQEKEELQ---QINETSQSQLN 240 >gi|237858682 neurofascin isoform 6 precursor [Homo sapiens] Length = 613 Score = 31.2 bits (69), Expect = 3.6 Identities = 33/138 (23%), Positives = 56/138 (40%), Gaps = 28/138 (20%) Query: 366 NPAMDFTQTPPGMLALDNMLYFAKHHQDAYIRIVLENSSREDKHECPFGRSSIELTKMLC 425 N + PP ML+ N L IR++L N +R D CPF S I + Sbjct: 414 NAFVSVLDVPPRMLSPRNQL----------IRVILYNRTRLD---CPFFGSPIPTLRWF- 459 Query: 426 EILKVGELPSETCNDFH---------PMFFTHDRSFEEFFCICIQLLNKTWKEMRATSED 476 K G+ + ++H M D+ + C+ +L K ++R +D Sbjct: 460 ---KNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGI--YTCVATNILGKAENQVRLEVKD 514 Query: 477 FNKVMQVVKEQVMRALTT 494 ++ ++ ++QV R TT Sbjct: 515 PTRIYRMPEDQVARRGTT 532 >gi|237858680 neurofascin isoform 5 precursor [Homo sapiens] Length = 619 Score = 31.2 bits (69), Expect = 3.6 Identities = 33/138 (23%), Positives = 56/138 (40%), Gaps = 28/138 (20%) Query: 366 NPAMDFTQTPPGMLALDNMLYFAKHHQDAYIRIVLENSSREDKHECPFGRSSIELTKMLC 425 N + PP ML+ N L IR++L N +R D CPF S I + Sbjct: 420 NAFVSVLDVPPRMLSPRNQL----------IRVILYNRTRLD---CPFFGSPIPTLRWF- 465 Query: 426 EILKVGELPSETCNDFH---------PMFFTHDRSFEEFFCICIQLLNKTWKEMRATSED 476 K G+ + ++H M D+ + C+ +L K ++R +D Sbjct: 466 ---KNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGI--YTCVATNILGKAENQVRLEVKD 520 Query: 477 FNKVMQVVKEQVMRALTT 494 ++ ++ ++QV R TT Sbjct: 521 PTRIYRMPEDQVARRGTT 538 >gi|237858675 neurofascin isoform 1 precursor [Homo sapiens] Length = 1240 Score = 31.2 bits (69), Expect = 3.6 Identities = 33/138 (23%), Positives = 56/138 (40%), Gaps = 28/138 (20%) Query: 366 NPAMDFTQTPPGMLALDNMLYFAKHHQDAYIRIVLENSSREDKHECPFGRSSIELTKMLC 425 N + PP ML+ N L IR++L N +R D CPF S I + Sbjct: 420 NAFVSVLDVPPRMLSPRNQL----------IRVILYNRTRLD---CPFFGSPIPTLRWF- 465 Query: 426 EILKVGELPSETCNDFH---------PMFFTHDRSFEEFFCICIQLLNKTWKEMRATSED 476 K G+ + ++H M D+ + C+ +L K ++R +D Sbjct: 466 ---KNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGI--YTCVATNILGKAENQVRLEVKD 520 Query: 477 FNKVMQVVKEQVMRALTT 494 ++ ++ ++QV R TT Sbjct: 521 PTRIYRMPEDQVARRGTT 538 >gi|203098650 ELMO/CED-12 domain containing 3 isoform b [Homo sapiens] Length = 381 Score = 31.2 bits (69), Expect = 3.6 Identities = 40/195 (20%), Positives = 75/195 (38%), Gaps = 20/195 (10%) Query: 312 KMDPQDQAQRDIIFELRRIAFDAESEPNNSSGSMEKRK--------SMYTRDYKKLGFIN 363 K+ + + +RD++ + + D++ + +K +++ ++ LGF Sbjct: 144 KLHQRLREERDLVLTIAQCGLDSQDPVHGRVLQTIYKKLTGSKFDCALHGNHWEDLGF-Q 202 Query: 364 HVNPAMDFTQTPPGMLALDNMLYFAKHHQDAYIRIVLENSSREDKHECPFGRSSIELTKM 423 NPA D G LAL ++LY + + + SR + PF S+ +T + Sbjct: 203 GANPATDLRGA--GFLALLHLLYLVMDSKTLPMAQEIFRLSRHHIQQFPFCLMSVNITHI 260 Query: 424 LCEILKVGELPSETCNDFHPMFFTHDRSFEEFFCICIQLLNKTWKEMRATSEDFNKVMQ- 482 + L+ E S CN + F+ L W+ R T D V++ Sbjct: 261 AIQALR-EECLSRECNRQQKVI----PVVNSFYAATFLHLAHVWRTQRKTISDSGFVLKE 315 Query: 483 ---VVKEQVMRALTT 494 + K+ R L T Sbjct: 316 LEVLAKKSPRRLLKT 330 >gi|203098539 ELMO/CED-12 domain containing 3 isoform b [Homo sapiens] Length = 381 Score = 31.2 bits (69), Expect = 3.6 Identities = 40/195 (20%), Positives = 75/195 (38%), Gaps = 20/195 (10%) Query: 312 KMDPQDQAQRDIIFELRRIAFDAESEPNNSSGSMEKRK--------SMYTRDYKKLGFIN 363 K+ + + +RD++ + + D++ + +K +++ ++ LGF Sbjct: 144 KLHQRLREERDLVLTIAQCGLDSQDPVHGRVLQTIYKKLTGSKFDCALHGNHWEDLGF-Q 202 Query: 364 HVNPAMDFTQTPPGMLALDNMLYFAKHHQDAYIRIVLENSSREDKHECPFGRSSIELTKM 423 NPA D G LAL ++LY + + + SR + PF S+ +T + Sbjct: 203 GANPATDLRGA--GFLALLHLLYLVMDSKTLPMAQEIFRLSRHHIQQFPFCLMSVNITHI 260 Query: 424 LCEILKVGELPSETCNDFHPMFFTHDRSFEEFFCICIQLLNKTWKEMRATSEDFNKVMQ- 482 + L+ E S CN + F+ L W+ R T D V++ Sbjct: 261 AIQALR-EECLSRECNRQQKVI----PVVNSFYAATFLHLAHVWRTQRKTISDSGFVLKE 315 Query: 483 ---VVKEQVMRALTT 494 + K+ R L T Sbjct: 316 LEVLAKKSPRRLLKT 330 >gi|203098474 ELMO/CED-12 domain containing 3 isoform b [Homo sapiens] Length = 381 Score = 31.2 bits (69), Expect = 3.6 Identities = 40/195 (20%), Positives = 75/195 (38%), Gaps = 20/195 (10%) Query: 312 KMDPQDQAQRDIIFELRRIAFDAESEPNNSSGSMEKRK--------SMYTRDYKKLGFIN 363 K+ + + +RD++ + + D++ + +K +++ ++ LGF Sbjct: 144 KLHQRLREERDLVLTIAQCGLDSQDPVHGRVLQTIYKKLTGSKFDCALHGNHWEDLGF-Q 202 Query: 364 HVNPAMDFTQTPPGMLALDNMLYFAKHHQDAYIRIVLENSSREDKHECPFGRSSIELTKM 423 NPA D G LAL ++LY + + + SR + PF S+ +T + Sbjct: 203 GANPATDLRGA--GFLALLHLLYLVMDSKTLPMAQEIFRLSRHHIQQFPFCLMSVNITHI 260 Query: 424 LCEILKVGELPSETCNDFHPMFFTHDRSFEEFFCICIQLLNKTWKEMRATSEDFNKVMQ- 482 + L+ E S CN + F+ L W+ R T D V++ Sbjct: 261 AIQALR-EECLSRECNRQQKVI----PVVNSFYAATFLHLAHVWRTQRKTISDSGFVLKE 315 Query: 483 ---VVKEQVMRALTT 494 + K+ R L T Sbjct: 316 LEVLAKKSPRRLLKT 330 >gi|21362032 ELMO/CED-12 domain containing 3 isoform a [Homo sapiens] Length = 391 Score = 31.2 bits (69), Expect = 3.6 Identities = 37/181 (20%), Positives = 70/181 (38%), Gaps = 16/181 (8%) Query: 312 KMDPQDQAQRDIIFELRRIAFDAESEPNNSSGSMEKRK--------SMYTRDYKKLGFIN 363 K+ + + +RD++ + + D++ + +K +++ ++ LGF Sbjct: 144 KLHQRLREERDLVLTIAQCGLDSQDPVHGRVLQTIYKKLTGSKFDCALHGNHWEDLGF-Q 202 Query: 364 HVNPAMDFTQTPPGMLALDNMLYFAKHHQDAYIRIVLENSSREDKHECPFGRSSIELTKM 423 NPA D G LAL ++LY + + + SR + PF S+ +T + Sbjct: 203 GANPATDLRGA--GFLALLHLLYLVMDSKTLPMAQEIFRLSRHHIQQFPFCLMSVNITHI 260 Query: 424 LCEILKVGELPSETCNDFHPMFFTHDRSFEEFFCICIQLLNKTWKEMRATSEDFNKVMQV 483 + L+ E S CN + F+ L W+ R T D V++ Sbjct: 261 AIQALR-EECLSRECNRQQKVI----PVVNSFYAATFLHLAHVWRTQRKTISDSGFVLKG 315 Query: 484 V 484 V Sbjct: 316 V 316 >gi|239756999 PREDICTED: ankyrin repeat domain 62 [Homo sapiens] Length = 917 Score = 30.8 bits (68), Expect = 4.6 Identities = 54/226 (23%), Positives = 88/226 (38%), Gaps = 41/226 (18%) Query: 450 RSFEEFFCICIQLLNKTWKEMRATSEDFNKVMQVVKEQVMRALTTKPSSLDQFKSKLQNL 509 RS E+ C C +L K K S V+Q V + + + Q K KL NL Sbjct: 430 RSIEDQKCYCERLKVKFQKMKNNIS-----VLQKVLSETDKTKSQSEHQNLQGKKKLCNL 484 Query: 510 SYTEILKIRQSERMNQEDFQSRPILELK--EKIQPEILELIKQQRLN--------RLVEG 559 + IL+ ++ ER+ E+ + I ELK E+ E+ KQ +L + V Sbjct: 485 RF--ILQQQEEERIKAEELYEKDIEELKIMEEQYRTQTEVKKQSKLTLKSLEVELKTVRS 542 Query: 560 TCFRKLNARRRQDKFWYCRLSPNHKVLHYGDLEESPQGEVPHDSLQDKLPVADIKAVVTG 619 + + R+ W NH + +E + + D+++ + + K Sbjct: 543 NSNQNFHTHERERDLW----QENHLM-----RDEIARLRLEIDTIKHQNQETENKYF--- 590 Query: 620 KDCPHMKEKG-----ALKQNKEVL-------ELAFSILYDSNCQLN 653 KD +KE LK+N+E L ++L D N LN Sbjct: 591 KDIEIIKENNEDLEKTLKRNEETLTKTITRYSKELNVLMDENTMLN 636 >gi|239751514 PREDICTED: ankyrin repeat domain 62 isoform 4 [Homo sapiens] Length = 917 Score = 30.8 bits (68), Expect = 4.6 Identities = 54/226 (23%), Positives = 88/226 (38%), Gaps = 41/226 (18%) Query: 450 RSFEEFFCICIQLLNKTWKEMRATSEDFNKVMQVVKEQVMRALTTKPSSLDQFKSKLQNL 509 RS E+ C C +L K K S V+Q V + + + Q K KL NL Sbjct: 430 RSIEDQKCYCERLKVKFQKMKNNIS-----VLQKVLSETDKTKSQSEHQNLQGKKKLCNL 484 Query: 510 SYTEILKIRQSERMNQEDFQSRPILELK--EKIQPEILELIKQQRLN--------RLVEG 559 + IL+ ++ ER+ E+ + I ELK E+ E+ KQ +L + V Sbjct: 485 RF--ILQQQEEERIKAEELYEKDIEELKIMEEQYRTQTEVKKQSKLTLKSLEVELKTVRS 542 Query: 560 TCFRKLNARRRQDKFWYCRLSPNHKVLHYGDLEESPQGEVPHDSLQDKLPVADIKAVVTG 619 + + R+ W NH + +E + + D+++ + + K Sbjct: 543 NSNQNFHTHERERDLW----QENHLM-----RDEIARLRLEIDTIKHQNQETENKYF--- 590 Query: 620 KDCPHMKEKG-----ALKQNKEVL-------ELAFSILYDSNCQLN 653 KD +KE LK+N+E L ++L D N LN Sbjct: 591 KDIEIIKENNEDLEKTLKRNEETLTKTITRYSKELNVLMDENTMLN 636 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.320 0.134 0.389 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 25,902,615 Number of Sequences: 37866 Number of extensions: 1078556 Number of successful extensions: 3386 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 6 Number of HSP's successfully gapped in prelim test: 36 Number of HSP's that attempted gapping in prelim test: 3349 Number of HSP's gapped (non-prelim): 66 length of query: 727 length of database: 18,247,518 effective HSP length: 110 effective length of query: 617 effective length of database: 14,082,258 effective search space: 8688753186 effective search space used: 8688753186 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.