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Search of human proteins with 10834992
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|10834992 interleukin 13 receptor, alpha 2 precursor [Homo
sapiens]
(380 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|10834992 interleukin 13 receptor, alpha 2 precursor [Homo sap... 815 0.0
gi|28559021 interleukin 5 receptor, alpha isoform 1 precursor [H... 111 9e-25
gi|28559027 interleukin 5 receptor, alpha isoform 1 precursor [H... 111 9e-25
gi|28559023 interleukin 5 receptor, alpha isoform 2 precursor [H... 107 2e-23
gi|28559025 interleukin 5 receptor, alpha isoform 3 precursor [H... 107 2e-23
gi|28559031 interleukin 5 receptor, alpha isoform 3 precursor [H... 107 2e-23
gi|28559029 interleukin 5 receptor, alpha isoform 2 precursor [H... 107 2e-23
gi|4504647 interleukin 13 receptor, alpha 1 precursor [Homo sapi... 100 2e-21
gi|4557882 interleukin 2 receptor, gamma precursor [Homo sapiens] 82 1e-15
gi|4559408 colony stimulating factor 2 receptor, beta precursor ... 55 1e-07
gi|4506107 prolactin receptor [Homo sapiens] 55 1e-07
gi|20070195 colony stimulating factor 2 receptor alpha chain iso... 52 1e-06
gi|238908519 colony stimulating factor 2 receptor alpha chain is... 52 1e-06
gi|238908515 colony stimulating factor 2 receptor alpha chain is... 52 1e-06
gi|27437032 colony stimulating factor 2 receptor alpha chain iso... 52 1e-06
gi|238908517 colony stimulating factor 2 receptor alpha chain is... 50 3e-06
gi|27437036 colony stimulating factor 2 receptor alpha chain iso... 50 3e-06
gi|27437034 colony stimulating factor 2 receptor alpha chain iso... 50 3e-06
gi|4758062 cytokine receptor-like factor 1 [Homo sapiens] 50 3e-06
gi|4504643 interleukin 12 receptor, beta 2 precursor [Homo sapiens] 47 3e-05
gi|13324710 interleukin 3 receptor, alpha precursor [Homo sapiens] 47 4e-05
gi|4504993 leukemia inhibitory factor receptor precursor [Homo s... 44 3e-04
gi|189083786 leukemia inhibitory factor receptor precursor [Homo... 44 3e-04
gi|115430248 gp130-like monocyte receptor [Homo sapiens] 44 3e-04
gi|28610149 interleukin 6 signal transducer isoform 2 precursor ... 43 4e-04
gi|28610147 interleukin 6 signal transducer isoform 1 precursor ... 43 4e-04
gi|27437040 colony stimulating factor 2 receptor alpha chain iso... 43 4e-04
gi|238908521 colony stimulating factor 2 receptor alpha chain is... 42 0.001
gi|51093381 leptin receptor isoform 3 [Homo sapiens] 41 0.002
gi|51093379 leptin receptor isoform 2 [Homo sapiens] 41 0.002
>gi|10834992 interleukin 13 receptor, alpha 2 precursor [Homo
sapiens]
Length = 380
Score = 815 bits (2104), Expect = 0.0
Identities = 380/380 (100%), Positives = 380/380 (100%)
Query: 1 MAFVCLAIGCLYTFLISTTFGCTSSSDTEIKVNPPQDFEIVDPGYLGYLYLQWQPPLSLD 60
MAFVCLAIGCLYTFLISTTFGCTSSSDTEIKVNPPQDFEIVDPGYLGYLYLQWQPPLSLD
Sbjct: 1 MAFVCLAIGCLYTFLISTTFGCTSSSDTEIKVNPPQDFEIVDPGYLGYLYLQWQPPLSLD 60
Query: 61 HFKECTVEYELKYRNIGSETWKTIITKNLHYKDGFDLNKGIEAKIHTLLPWQCTNGSEVQ 120
HFKECTVEYELKYRNIGSETWKTIITKNLHYKDGFDLNKGIEAKIHTLLPWQCTNGSEVQ
Sbjct: 61 HFKECTVEYELKYRNIGSETWKTIITKNLHYKDGFDLNKGIEAKIHTLLPWQCTNGSEVQ 120
Query: 121 SSWAETTYWISPQGIPETKVQDMDCVYYNWQYLLCSWKPGIGVLLDTNYNLFYWYEGLDH 180
SSWAETTYWISPQGIPETKVQDMDCVYYNWQYLLCSWKPGIGVLLDTNYNLFYWYEGLDH
Sbjct: 121 SSWAETTYWISPQGIPETKVQDMDCVYYNWQYLLCSWKPGIGVLLDTNYNLFYWYEGLDH 180
Query: 181 ALQCVDYIKADGQNIGCRFPYLEASDYKDFYICVNGSSENKPIRSSYFTFQLQNIVKPLP 240
ALQCVDYIKADGQNIGCRFPYLEASDYKDFYICVNGSSENKPIRSSYFTFQLQNIVKPLP
Sbjct: 181 ALQCVDYIKADGQNIGCRFPYLEASDYKDFYICVNGSSENKPIRSSYFTFQLQNIVKPLP 240
Query: 241 PVYLTFTRESSCEIKLKWSIPLGPIPARCFDYEIEIREDDTTLVTATVENETYTLKTTNE 300
PVYLTFTRESSCEIKLKWSIPLGPIPARCFDYEIEIREDDTTLVTATVENETYTLKTTNE
Sbjct: 241 PVYLTFTRESSCEIKLKWSIPLGPIPARCFDYEIEIREDDTTLVTATVENETYTLKTTNE 300
Query: 301 TRQLCFVVRSKVNIYCSDDGIWSEWSDKQCWEGEDLSKKTLLRFWLPFGFILILVIFVTG 360
TRQLCFVVRSKVNIYCSDDGIWSEWSDKQCWEGEDLSKKTLLRFWLPFGFILILVIFVTG
Sbjct: 301 TRQLCFVVRSKVNIYCSDDGIWSEWSDKQCWEGEDLSKKTLLRFWLPFGFILILVIFVTG 360
Query: 361 LLLRKPNTYPKMIPEFFCDT 380
LLLRKPNTYPKMIPEFFCDT
Sbjct: 361 LLLRKPNTYPKMIPEFFCDT 380
>gi|28559021 interleukin 5 receptor, alpha isoform 1 precursor [Homo
sapiens]
Length = 420
Score = 111 bits (278), Expect = 9e-25
Identities = 96/351 (27%), Positives = 160/351 (45%), Gaps = 33/351 (9%)
Query: 27 DTEIKVNPPQDFEIVDPGYLGYLYLQWQPPLSLDHFKECTVEYELKYRNIGSETWKTIIT 86
D +I + PP +F I G L + LQW+P + + +EY++K + ++T IT
Sbjct: 25 DEKISLLPPVNFTIKVTG-LAQVLLQWKPNPDQEQ-RNVNLEYQVKINAPKEDDYETRIT 82
Query: 87 KNLHYKDGFDLNKGIEAKIHTLLPWQCTNGSEVQSSWAETTYWISPQGIPETKVQDMDCV 146
++ K L+KG A + T+L + S + SSWA +P G P T + ++ C
Sbjct: 83 ES---KCVTILHKGFSASVRTILQ---NDHSLLASSWASAELH-APPGSPGTSIVNLTCT 135
Query: 147 YYNWQ-----------YLLCSWKPGIGVLLDTNYNLFYWYEGLDHALQCVDYIKAD-GQN 194
+ L C+W G DT Y L+Y Y +C +Y K G+N
Sbjct: 136 TNTTEDNYSRLRSYQVSLHCTWLVGTDAPEDTQYFLYYRYGSWTE--ECQEYSKDTLGRN 193
Query: 195 IGCRFP--YLEASDYKDFYICVNGSSENKPIRSSYFTFQLQNIVKPLPPVYLTFTRESSC 252
I C FP ++ + + VNGSS++ IR F L I + PP+ +T E +
Sbjct: 194 IACWFPRTFILSKGRDWLAVLVNGSSKHSAIRPFDQLFALHAIDQINPPLNVTAEIEGT- 252
Query: 253 EIKLKWSIPLGPIPARCFDYEIEIREDDTTLVTATVENETYTLKTTNETRQLCFVVRSKV 312
+ ++W P+ P CFDYE++I + + ++ + VR+ V
Sbjct: 253 RLSIQWEKPVSAFPIHCFDYEVKIHNTRNGYLQIEKLMTNAFISIIDDLSKYDVQVRAAV 312
Query: 313 NIYCSDDGIWSEWSDKQCWEGEDLSKKTLLRFWLPFGFILILVIFVTGLLL 363
+ C + G+WSEWS + + G D K LR W F+++++ + +LL
Sbjct: 313 SSMCREAGLWSEWS-QPIYVGNDEHKP--LREW----FVIVIMATICFILL 356
>gi|28559027 interleukin 5 receptor, alpha isoform 1 precursor [Homo
sapiens]
Length = 420
Score = 111 bits (278), Expect = 9e-25
Identities = 96/351 (27%), Positives = 160/351 (45%), Gaps = 33/351 (9%)
Query: 27 DTEIKVNPPQDFEIVDPGYLGYLYLQWQPPLSLDHFKECTVEYELKYRNIGSETWKTIIT 86
D +I + PP +F I G L + LQW+P + + +EY++K + ++T IT
Sbjct: 25 DEKISLLPPVNFTIKVTG-LAQVLLQWKPNPDQEQ-RNVNLEYQVKINAPKEDDYETRIT 82
Query: 87 KNLHYKDGFDLNKGIEAKIHTLLPWQCTNGSEVQSSWAETTYWISPQGIPETKVQDMDCV 146
++ K L+KG A + T+L + S + SSWA +P G P T + ++ C
Sbjct: 83 ES---KCVTILHKGFSASVRTILQ---NDHSLLASSWASAELH-APPGSPGTSIVNLTCT 135
Query: 147 YYNWQ-----------YLLCSWKPGIGVLLDTNYNLFYWYEGLDHALQCVDYIKAD-GQN 194
+ L C+W G DT Y L+Y Y +C +Y K G+N
Sbjct: 136 TNTTEDNYSRLRSYQVSLHCTWLVGTDAPEDTQYFLYYRYGSWTE--ECQEYSKDTLGRN 193
Query: 195 IGCRFP--YLEASDYKDFYICVNGSSENKPIRSSYFTFQLQNIVKPLPPVYLTFTRESSC 252
I C FP ++ + + VNGSS++ IR F L I + PP+ +T E +
Sbjct: 194 IACWFPRTFILSKGRDWLAVLVNGSSKHSAIRPFDQLFALHAIDQINPPLNVTAEIEGT- 252
Query: 253 EIKLKWSIPLGPIPARCFDYEIEIREDDTTLVTATVENETYTLKTTNETRQLCFVVRSKV 312
+ ++W P+ P CFDYE++I + + ++ + VR+ V
Sbjct: 253 RLSIQWEKPVSAFPIHCFDYEVKIHNTRNGYLQIEKLMTNAFISIIDDLSKYDVQVRAAV 312
Query: 313 NIYCSDDGIWSEWSDKQCWEGEDLSKKTLLRFWLPFGFILILVIFVTGLLL 363
+ C + G+WSEWS + + G D K LR W F+++++ + +LL
Sbjct: 313 SSMCREAGLWSEWS-QPIYVGNDEHKP--LREW----FVIVIMATICFILL 356
>gi|28559023 interleukin 5 receptor, alpha isoform 2 precursor [Homo
sapiens]
Length = 333
Score = 107 bits (267), Expect = 2e-23
Identities = 87/314 (27%), Positives = 142/314 (45%), Gaps = 26/314 (8%)
Query: 27 DTEIKVNPPQDFEIVDPGYLGYLYLQWQPPLSLDHFKECTVEYELKYRNIGSETWKTIIT 86
D +I + PP +F I G L + LQW+P + + +EY++K + ++T IT
Sbjct: 25 DEKISLLPPVNFTIKVTG-LAQVLLQWKPNPDQEQ-RNVNLEYQVKINAPKEDDYETRIT 82
Query: 87 KNLHYKDGFDLNKGIEAKIHTLLPWQCTNGSEVQSSWAETTYWISPQGIPETKVQDMDCV 146
++ K L+KG A + T+L + S + SSWA +P G P T + ++ C
Sbjct: 83 ES---KCVTILHKGFSASVRTILQ---NDHSLLASSWASAELH-APPGSPGTSIVNLTCT 135
Query: 147 YYNWQ-----------YLLCSWKPGIGVLLDTNYNLFYWYEGLDHALQCVDYIKAD-GQN 194
+ L C+W G DT Y L+Y Y +C +Y K G+N
Sbjct: 136 TNTTEDNYSRLRSYQVSLHCTWLVGTDAPEDTQYFLYYRYGSWTE--ECQEYSKDTLGRN 193
Query: 195 IGCRFP--YLEASDYKDFYICVNGSSENKPIRSSYFTFQLQNIVKPLPPVYLTFTRESSC 252
I C FP ++ + + VNGSS++ IR F L I + PP+ +T E +
Sbjct: 194 IACWFPRTFILSKGRDWLAVLVNGSSKHSAIRPFDQLFALHAIDQINPPLNVTAEIEGT- 252
Query: 253 EIKLKWSIPLGPIPARCFDYEIEIREDDTTLVTATVENETYTLKTTNETRQLCFVVRSKV 312
+ ++W P+ P CFDYE++I + + ++ + VR+ V
Sbjct: 253 RLSIQWEKPVSAFPIHCFDYEVKIHNTRNGYLQIEKLMTNAFISIIDDLSKYDVQVRAAV 312
Query: 313 NIYCSDDGIWSEWS 326
+ C + G+WSEWS
Sbjct: 313 SSMCREAGLWSEWS 326
>gi|28559025 interleukin 5 receptor, alpha isoform 3 precursor [Homo
sapiens]
Length = 335
Score = 107 bits (267), Expect = 2e-23
Identities = 87/314 (27%), Positives = 142/314 (45%), Gaps = 26/314 (8%)
Query: 27 DTEIKVNPPQDFEIVDPGYLGYLYLQWQPPLSLDHFKECTVEYELKYRNIGSETWKTIIT 86
D +I + PP +F I G L + LQW+P + + +EY++K + ++T IT
Sbjct: 25 DEKISLLPPVNFTIKVTG-LAQVLLQWKPNPDQEQ-RNVNLEYQVKINAPKEDDYETRIT 82
Query: 87 KNLHYKDGFDLNKGIEAKIHTLLPWQCTNGSEVQSSWAETTYWISPQGIPETKVQDMDCV 146
++ K L+KG A + T+L + S + SSWA +P G P T + ++ C
Sbjct: 83 ES---KCVTILHKGFSASVRTILQ---NDHSLLASSWASAELH-APPGSPGTSIVNLTCT 135
Query: 147 YYNWQ-----------YLLCSWKPGIGVLLDTNYNLFYWYEGLDHALQCVDYIKAD-GQN 194
+ L C+W G DT Y L+Y Y +C +Y K G+N
Sbjct: 136 TNTTEDNYSRLRSYQVSLHCTWLVGTDAPEDTQYFLYYRYGSWTE--ECQEYSKDTLGRN 193
Query: 195 IGCRFP--YLEASDYKDFYICVNGSSENKPIRSSYFTFQLQNIVKPLPPVYLTFTRESSC 252
I C FP ++ + + VNGSS++ IR F L I + PP+ +T E +
Sbjct: 194 IACWFPRTFILSKGRDWLAVLVNGSSKHSAIRPFDQLFALHAIDQINPPLNVTAEIEGT- 252
Query: 253 EIKLKWSIPLGPIPARCFDYEIEIREDDTTLVTATVENETYTLKTTNETRQLCFVVRSKV 312
+ ++W P+ P CFDYE++I + + ++ + VR+ V
Sbjct: 253 RLSIQWEKPVSAFPIHCFDYEVKIHNTRNGYLQIEKLMTNAFISIIDDLSKYDVQVRAAV 312
Query: 313 NIYCSDDGIWSEWS 326
+ C + G+WSEWS
Sbjct: 313 SSMCREAGLWSEWS 326
>gi|28559031 interleukin 5 receptor, alpha isoform 3 precursor [Homo
sapiens]
Length = 335
Score = 107 bits (267), Expect = 2e-23
Identities = 87/314 (27%), Positives = 142/314 (45%), Gaps = 26/314 (8%)
Query: 27 DTEIKVNPPQDFEIVDPGYLGYLYLQWQPPLSLDHFKECTVEYELKYRNIGSETWKTIIT 86
D +I + PP +F I G L + LQW+P + + +EY++K + ++T IT
Sbjct: 25 DEKISLLPPVNFTIKVTG-LAQVLLQWKPNPDQEQ-RNVNLEYQVKINAPKEDDYETRIT 82
Query: 87 KNLHYKDGFDLNKGIEAKIHTLLPWQCTNGSEVQSSWAETTYWISPQGIPETKVQDMDCV 146
++ K L+KG A + T+L + S + SSWA +P G P T + ++ C
Sbjct: 83 ES---KCVTILHKGFSASVRTILQ---NDHSLLASSWASAELH-APPGSPGTSIVNLTCT 135
Query: 147 YYNWQ-----------YLLCSWKPGIGVLLDTNYNLFYWYEGLDHALQCVDYIKAD-GQN 194
+ L C+W G DT Y L+Y Y +C +Y K G+N
Sbjct: 136 TNTTEDNYSRLRSYQVSLHCTWLVGTDAPEDTQYFLYYRYGSWTE--ECQEYSKDTLGRN 193
Query: 195 IGCRFP--YLEASDYKDFYICVNGSSENKPIRSSYFTFQLQNIVKPLPPVYLTFTRESSC 252
I C FP ++ + + VNGSS++ IR F L I + PP+ +T E +
Sbjct: 194 IACWFPRTFILSKGRDWLAVLVNGSSKHSAIRPFDQLFALHAIDQINPPLNVTAEIEGT- 252
Query: 253 EIKLKWSIPLGPIPARCFDYEIEIREDDTTLVTATVENETYTLKTTNETRQLCFVVRSKV 312
+ ++W P+ P CFDYE++I + + ++ + VR+ V
Sbjct: 253 RLSIQWEKPVSAFPIHCFDYEVKIHNTRNGYLQIEKLMTNAFISIIDDLSKYDVQVRAAV 312
Query: 313 NIYCSDDGIWSEWS 326
+ C + G+WSEWS
Sbjct: 313 SSMCREAGLWSEWS 326
>gi|28559029 interleukin 5 receptor, alpha isoform 2 precursor [Homo
sapiens]
Length = 333
Score = 107 bits (267), Expect = 2e-23
Identities = 87/314 (27%), Positives = 142/314 (45%), Gaps = 26/314 (8%)
Query: 27 DTEIKVNPPQDFEIVDPGYLGYLYLQWQPPLSLDHFKECTVEYELKYRNIGSETWKTIIT 86
D +I + PP +F I G L + LQW+P + + +EY++K + ++T IT
Sbjct: 25 DEKISLLPPVNFTIKVTG-LAQVLLQWKPNPDQEQ-RNVNLEYQVKINAPKEDDYETRIT 82
Query: 87 KNLHYKDGFDLNKGIEAKIHTLLPWQCTNGSEVQSSWAETTYWISPQGIPETKVQDMDCV 146
++ K L+KG A + T+L + S + SSWA +P G P T + ++ C
Sbjct: 83 ES---KCVTILHKGFSASVRTILQ---NDHSLLASSWASAELH-APPGSPGTSIVNLTCT 135
Query: 147 YYNWQ-----------YLLCSWKPGIGVLLDTNYNLFYWYEGLDHALQCVDYIKAD-GQN 194
+ L C+W G DT Y L+Y Y +C +Y K G+N
Sbjct: 136 TNTTEDNYSRLRSYQVSLHCTWLVGTDAPEDTQYFLYYRYGSWTE--ECQEYSKDTLGRN 193
Query: 195 IGCRFP--YLEASDYKDFYICVNGSSENKPIRSSYFTFQLQNIVKPLPPVYLTFTRESSC 252
I C FP ++ + + VNGSS++ IR F L I + PP+ +T E +
Sbjct: 194 IACWFPRTFILSKGRDWLAVLVNGSSKHSAIRPFDQLFALHAIDQINPPLNVTAEIEGT- 252
Query: 253 EIKLKWSIPLGPIPARCFDYEIEIREDDTTLVTATVENETYTLKTTNETRQLCFVVRSKV 312
+ ++W P+ P CFDYE++I + + ++ + VR+ V
Sbjct: 253 RLSIQWEKPVSAFPIHCFDYEVKIHNTRNGYLQIEKLMTNAFISIIDDLSKYDVQVRAAV 312
Query: 313 NIYCSDDGIWSEWS 326
+ C + G+WSEWS
Sbjct: 313 SSMCREAGLWSEWS 326
>gi|4504647 interleukin 13 receptor, alpha 1 precursor [Homo
sapiens]
Length = 427
Score = 100 bits (250), Expect = 2e-21
Identities = 78/275 (28%), Positives = 122/275 (44%), Gaps = 37/275 (13%)
Query: 112 QC-TNGSEVQSSWAETTYWISPQGIPETKVQDMDCVYYNWQYLLCSWKPGIGVLLDTNYN 170
QC TN SE S E P+G PE+ V ++ C+++N Y+ CSW PG DTNY
Sbjct: 101 QCSTNESEKPSILVEKCI-SPPEGDPESAVTELQCIWHNLSYMKCSWLPGRNTSPDTNYT 159
Query: 171 LFYWYEGLDHALQCVDYIKADGQNIGCRFPYLEASD--YKDFYICVNGSSENKPIRSSYF 228
L+YW+ L+ QC + I +GQ GC F + D ++ + + I+ S+
Sbjct: 160 LYYWHRSLEKIHQC-ENIFREGQYFGCSFDLTKVKDSSFEQHSVQIMVKDNAGKIKPSFN 218
Query: 229 TFQLQNIVKPLPPVYLTFTRESSCEIKLKWSIPLGPIPARCFDYEIEIREDDTT------ 282
L + VKP PP + + ++ ++W P I +RC YE+E+ T
Sbjct: 219 IVPLTSRVKPDPPHIKNLSFHND-DLYVQWENPQNFI-SRCLFYEVEVNNSQTETHNVFY 276
Query: 283 LVTATVENETYTLKTTNETRQLCFVV-------------RSKVNIYC-SDDGIWSEWSDK 328
+ A EN + N + CF+V R K N C DD +WS WS +
Sbjct: 277 VQEAKCENPEFERNVENTS---CFMVPGVLPDTLNTVRIRVKTNKLCYEDDKLWSNWSQE 333
Query: 329 QCWEGEDLSKKTLLRFWLPFGFILILVIFVTGLLL 363
+ KK ++ +LI+ + V G ++
Sbjct: 334 M-----SIGKKRNSTLYIT--MLLIVPVIVAGAII 361
>gi|4557882 interleukin 2 receptor, gamma precursor [Homo sapiens]
Length = 369
Score = 81.6 bits (200), Expect = 1e-15
Identities = 65/251 (25%), Positives = 111/251 (44%), Gaps = 18/251 (7%)
Query: 115 NGSE-VQSSWAETTYWISPQGIPETKVQDMDCVYYNWQYLLCSWKPGIGVLLDTNYNLFY 173
NG+E + + TT + + ++ C +N +Y+ C+W TN L Y
Sbjct: 31 NGNEDTTADFFLTTMPTDSLSVSTLPLPEVQCFVFNVEYMNCTWNSS-SEPQPTNLTLHY 89
Query: 174 WYEGLDH--ALQCVDYIKADGQNIGCRFPYLEASDYKDFYICVNGSSENKPIRSSYFTFQ 231
WY+ D+ +C Y+ ++ GC+ E Y+ F + + E P R + +
Sbjct: 90 WYKNSDNDKVQKCSHYLFSEEITSGCQLQKKEIHLYQTFVVQLQDPRE--PRRQATQMLK 147
Query: 232 LQNIVKPLPPVYLTFTRESSCEIKLKWSIPLGPIPARCFDYEIEIRED-DTTLVTATVE- 289
LQN+V P P LT + S +++L W+ C ++ ++ R D D + +V+
Sbjct: 148 LQNLVIPWAPENLTLHKLSESQLELNWN---NRFLNHCLEHLVQYRTDWDHSWTEQSVDY 204
Query: 290 NETYTLKTTNETRQLCFVVRSKVNIYCSDDGIWSEWSDKQCWEGEDLSKKTLLRFWLPFG 349
++L + + ++ F VRS+ N C WSEWS W G + SK+ PF
Sbjct: 205 RHKFSLPSVDGQKRYTFRVRSRFNPLCGSAQHWSEWSHPIHW-GSNTSKEN------PFL 257
Query: 350 FILILVIFVTG 360
F L V+ G
Sbjct: 258 FALEAVVISVG 268
>gi|4559408 colony stimulating factor 2 receptor, beta precursor
[Homo sapiens]
Length = 897
Score = 55.1 bits (131), Expect = 1e-07
Identities = 57/247 (23%), Positives = 101/247 (40%), Gaps = 28/247 (11%)
Query: 121 SSWAETTYWISPQGIPETKVQDMDCVYYNWQYLLCSWKPGIGVLLDTNYNLFYWYEGLDH 180
S W+ W S G E + Q+++C + L CSW+ V ++ LFY
Sbjct: 227 SKWSPEVCWDSQPG-DEAQPQNLECFFDGAAVLSCSWEVRKEVASSVSFGLFYKPSPDAG 285
Query: 181 ALQCVDYIKADGQNIG----CRFPYLEASDYKDFYICVNGSSENKPIRSSYFTFQLQNIV 236
+C ++ ++ C+ P + + + + + V K I+SS NI
Sbjct: 286 EEECSPVLREGLGSLHTRHHCQIPVPDPATHGQYIVSVQPRRAEKHIKSSV------NIQ 339
Query: 237 KPLPPVYLTFTRESSCEIKLKWSIPLGPIPARCFDYEIEIREDDTTLV---TATVEN-ET 292
P + +T +S L+W +EI+ R+D T T T++N +
Sbjct: 340 MAPPSLNVTKDGDS---YSLRWETMKMRYEHIDHTFEIQYRKDTATWKDSKTETLQNAHS 396
Query: 293 YTLKTTNETRQLCFVVRSKVNIYCSDDGIWSEWSDKQCWEGEDLSKKTLLRFWLPFGFIL 352
L + + VR + + +GIWSEWS+ + W+ E + LP +
Sbjct: 397 MALPALEPSTRYWARVRVRTS-RTGYNGIWSEWSEARSWDTESV---------LPMWVLA 446
Query: 353 ILVIFVT 359
++VIF+T
Sbjct: 447 LIVIFLT 453
>gi|4506107 prolactin receptor [Homo sapiens]
Length = 622
Score = 55.1 bits (131), Expect = 1e-07
Identities = 57/202 (28%), Positives = 83/202 (41%), Gaps = 18/202 (8%)
Query: 135 IPETKVQDMDCVYYNWQYLLCSWKPGIGVLLDTNYNLFYWYEGLDHALQCVDYIKADGQN 194
+P K + C N + C W+PG L TNY+L Y EG +C DYI G N
Sbjct: 26 LPPGKPEIFKCRSPNKETFTCWWRPGTDGGLPTNYSLTYHREGETLMHECPDYI-TGGPN 84
Query: 195 IGCRFPYLEASDYKDFYICVNGSSENKPIRSSYFTFQLQNIVKPLPPVYLTFTRESSCEI 254
C F S ++ + + VN +++ S + IV+P PP+ L + +
Sbjct: 85 -SCHFGKQYTSMWRTYIMMVNATNQMGSSFSDELYVDVTYIVQPDPPLELAVEVKQPEDR 143
Query: 255 K----LKWSIP-LGPIPARCFD--YEIEIREDDTTLVTATVENETYTLKTTNETRQLCFV 307
K +KWS P L + F YEI ++ + E E + E + L
Sbjct: 144 KPYLWIKWSPPTLIDLKTGWFTLLYEIRLKPE------KAAEWEIHFAGQQTEFKILSLH 197
Query: 308 VRSK--VNIYCS-DDGIWSEWS 326
K V + C D G WS WS
Sbjct: 198 PGQKYLVQVRCKPDHGYWSAWS 219
>gi|20070195 colony stimulating factor 2 receptor alpha chain
isoform a precursor [Homo sapiens]
Length = 400
Score = 51.6 bits (122), Expect = 1e-06
Identities = 50/235 (21%), Positives = 93/235 (39%), Gaps = 25/235 (10%)
Query: 138 TKVQDMDCVYYNWQYLLCSWKPGIGVLLDTNYNLFYWYEGLDHALQCVDYIKADGQNIGC 197
T Q+ C YN + C+W G D Y L+ ++C YI+ G ++GC
Sbjct: 119 TAAQNFSCFIYNADLMNCTWARGPTAPRDVQYFLYIRNSKRRREIRCPYYIQDSGTHVGC 178
Query: 198 RFPYLEASDYKDFYICVNGSSENKPIRSSYFTFQLQNIVKPLPPVYLTF-TRESSCEIKL 256
L +++++ VNG+S I+ + I + PP +T + C ++
Sbjct: 179 HLDNLSGLTSRNYFL-VNGTSREIGIQFFDSLLDTKKIERFNPPSNVTVRCNTTHCLVRW 237
Query: 257 KWSIPLGPIPARCFDYEIEIREDDT------TLVTATVENETYTLKTTNETRQLCFVVRS 310
K + F Y++++ +T L+ + + E ++E R +
Sbjct: 238 KQPRTYQKLSYLDFQYQLDVHRKNTQPGTENLLINVSGDLENRYNFPSSEPR-----AKH 292
Query: 311 KVNIYCSDDGI--WSEWSDKQCWEGEDLSKKTLLRFWLPFGFILILVIFVTGLLL 363
V I +D I WS WS+ + +D + G + I V+ + G L+
Sbjct: 293 SVKIRAADVRILNWSSWSEAIEFGSDDGN----------LGSVYIYVLLIVGTLV 337
>gi|238908519 colony stimulating factor 2 receptor alpha chain
isoform g precursor [Homo sapiens]
Length = 410
Score = 51.6 bits (122), Expect = 1e-06
Identities = 50/235 (21%), Positives = 93/235 (39%), Gaps = 25/235 (10%)
Query: 138 TKVQDMDCVYYNWQYLLCSWKPGIGVLLDTNYNLFYWYEGLDHALQCVDYIKADGQNIGC 197
T Q+ C YN + C+W G D Y L+ ++C YI+ G ++GC
Sbjct: 119 TAAQNFSCFIYNADLMNCTWARGPTAPRDVQYFLYIRNSKRRREIRCPYYIQDSGTHVGC 178
Query: 198 RFPYLEASDYKDFYICVNGSSENKPIRSSYFTFQLQNIVKPLPPVYLTF-TRESSCEIKL 256
L +++++ VNG+S I+ + I + PP +T + C ++
Sbjct: 179 HLDNLSGLTSRNYFL-VNGTSREIGIQFFDSLLDTKKIERFNPPSNVTVRCNTTHCLVRW 237
Query: 257 KWSIPLGPIPARCFDYEIEIREDDT------TLVTATVENETYTLKTTNETRQLCFVVRS 310
K + F Y++++ +T L+ + + E ++E R +
Sbjct: 238 KQPRTYQKLSYLDFQYQLDVHRKNTQPGTENLLINVSGDLENRYNFPSSEPR-----AKH 292
Query: 311 KVNIYCSDDGI--WSEWSDKQCWEGEDLSKKTLLRFWLPFGFILILVIFVTGLLL 363
V I +D I WS WS+ + +D + G + I V+ + G L+
Sbjct: 293 SVKIRAADVRILNWSSWSEAIEFGSDDGN----------LGSVYIYVLLIVGTLV 337
>gi|238908515 colony stimulating factor 2 receptor alpha chain
isoform a precursor [Homo sapiens]
Length = 400
Score = 51.6 bits (122), Expect = 1e-06
Identities = 50/235 (21%), Positives = 93/235 (39%), Gaps = 25/235 (10%)
Query: 138 TKVQDMDCVYYNWQYLLCSWKPGIGVLLDTNYNLFYWYEGLDHALQCVDYIKADGQNIGC 197
T Q+ C YN + C+W G D Y L+ ++C YI+ G ++GC
Sbjct: 119 TAAQNFSCFIYNADLMNCTWARGPTAPRDVQYFLYIRNSKRRREIRCPYYIQDSGTHVGC 178
Query: 198 RFPYLEASDYKDFYICVNGSSENKPIRSSYFTFQLQNIVKPLPPVYLTF-TRESSCEIKL 256
L +++++ VNG+S I+ + I + PP +T + C ++
Sbjct: 179 HLDNLSGLTSRNYFL-VNGTSREIGIQFFDSLLDTKKIERFNPPSNVTVRCNTTHCLVRW 237
Query: 257 KWSIPLGPIPARCFDYEIEIREDDT------TLVTATVENETYTLKTTNETRQLCFVVRS 310
K + F Y++++ +T L+ + + E ++E R +
Sbjct: 238 KQPRTYQKLSYLDFQYQLDVHRKNTQPGTENLLINVSGDLENRYNFPSSEPR-----AKH 292
Query: 311 KVNIYCSDDGI--WSEWSDKQCWEGEDLSKKTLLRFWLPFGFILILVIFVTGLLL 363
V I +D I WS WS+ + +D + G + I V+ + G L+
Sbjct: 293 SVKIRAADVRILNWSSWSEAIEFGSDDGN----------LGSVYIYVLLIVGTLV 337
>gi|27437032 colony stimulating factor 2 receptor alpha chain
isoform a precursor [Homo sapiens]
Length = 400
Score = 51.6 bits (122), Expect = 1e-06
Identities = 50/235 (21%), Positives = 93/235 (39%), Gaps = 25/235 (10%)
Query: 138 TKVQDMDCVYYNWQYLLCSWKPGIGVLLDTNYNLFYWYEGLDHALQCVDYIKADGQNIGC 197
T Q+ C YN + C+W G D Y L+ ++C YI+ G ++GC
Sbjct: 119 TAAQNFSCFIYNADLMNCTWARGPTAPRDVQYFLYIRNSKRRREIRCPYYIQDSGTHVGC 178
Query: 198 RFPYLEASDYKDFYICVNGSSENKPIRSSYFTFQLQNIVKPLPPVYLTF-TRESSCEIKL 256
L +++++ VNG+S I+ + I + PP +T + C ++
Sbjct: 179 HLDNLSGLTSRNYFL-VNGTSREIGIQFFDSLLDTKKIERFNPPSNVTVRCNTTHCLVRW 237
Query: 257 KWSIPLGPIPARCFDYEIEIREDDT------TLVTATVENETYTLKTTNETRQLCFVVRS 310
K + F Y++++ +T L+ + + E ++E R +
Sbjct: 238 KQPRTYQKLSYLDFQYQLDVHRKNTQPGTENLLINVSGDLENRYNFPSSEPR-----AKH 292
Query: 311 KVNIYCSDDGI--WSEWSDKQCWEGEDLSKKTLLRFWLPFGFILILVIFVTGLLL 363
V I +D I WS WS+ + +D + G + I V+ + G L+
Sbjct: 293 SVKIRAADVRILNWSSWSEAIEFGSDDGN----------LGSVYIYVLLIVGTLV 337
>gi|238908517 colony stimulating factor 2 receptor alpha chain
isoform f precursor [Homo sapiens]
Length = 434
Score = 50.4 bits (119), Expect = 3e-06
Identities = 44/199 (22%), Positives = 80/199 (40%), Gaps = 15/199 (7%)
Query: 138 TKVQDMDCVYYNWQYLLCSWKPGIGVLLDTNYNLFYWYEGLDHALQCVDYIKADGQNIGC 197
T Q+ C YN + C+W G D Y L+ ++C YI+ G ++GC
Sbjct: 119 TAAQNFSCFIYNADLMNCTWARGPTAPRDVQYFLYIRNSKRRREIRCPYYIQDSGTHVGC 178
Query: 198 RFPYLEASDYKDFYICVNGSSENKPIRSSYFTFQLQNIVKPLPPVYLTF-TRESSCEIKL 256
L +++++ VNG+S I+ + I + PP +T + C ++
Sbjct: 179 HLDNLSGLTSRNYFL-VNGTSREIGIQFFDSLLDTKKIERFNPPSNVTVRCNTTHCLVRW 237
Query: 257 KWSIPLGPIPARCFDYEIEIREDDT------TLVTATVENETYTLKTTNETRQLCFVVRS 310
K + F Y++++ +T L+ + + E ++E R +
Sbjct: 238 KQPRTYQKLSYLDFQYQLDVHRKNTQPGTENLLINVSGDLENRYNFPSSEPR-----AKH 292
Query: 311 KVNIYCSDDGI--WSEWSD 327
V I +D I WS WS+
Sbjct: 293 SVKIRAADVRILNWSSWSE 311
>gi|27437036 colony stimulating factor 2 receptor alpha chain
isoform c precursor [Homo sapiens]
Length = 333
Score = 50.4 bits (119), Expect = 3e-06
Identities = 44/199 (22%), Positives = 80/199 (40%), Gaps = 15/199 (7%)
Query: 138 TKVQDMDCVYYNWQYLLCSWKPGIGVLLDTNYNLFYWYEGLDHALQCVDYIKADGQNIGC 197
T Q+ C YN + C+W G D Y L+ ++C YI+ G ++GC
Sbjct: 119 TAAQNFSCFIYNADLMNCTWARGPTAPRDVQYFLYIRNSKRRREIRCPYYIQDSGTHVGC 178
Query: 198 RFPYLEASDYKDFYICVNGSSENKPIRSSYFTFQLQNIVKPLPPVYLTF-TRESSCEIKL 256
L +++++ VNG+S I+ + I + PP +T + C ++
Sbjct: 179 HLDNLSGLTSRNYFL-VNGTSREIGIQFFDSLLDTKKIERFNPPSNVTVRCNTTHCLVRW 237
Query: 257 KWSIPLGPIPARCFDYEIEIREDDT------TLVTATVENETYTLKTTNETRQLCFVVRS 310
K + F Y++++ +T L+ + + E ++E R +
Sbjct: 238 KQPRTYQKLSYLDFQYQLDVHRKNTQPGTENLLINVSGDLENRYNFPSSEPR-----AKH 292
Query: 311 KVNIYCSDDGI--WSEWSD 327
V I +D I WS WS+
Sbjct: 293 SVKIRAADVRILNWSSWSE 311
>gi|27437034 colony stimulating factor 2 receptor alpha chain
isoform b precursor [Homo sapiens]
Length = 377
Score = 50.4 bits (119), Expect = 3e-06
Identities = 44/199 (22%), Positives = 80/199 (40%), Gaps = 15/199 (7%)
Query: 138 TKVQDMDCVYYNWQYLLCSWKPGIGVLLDTNYNLFYWYEGLDHALQCVDYIKADGQNIGC 197
T Q+ C YN + C+W G D Y L+ ++C YI+ G ++GC
Sbjct: 119 TAAQNFSCFIYNADLMNCTWARGPTAPRDVQYFLYIRNSKRRREIRCPYYIQDSGTHVGC 178
Query: 198 RFPYLEASDYKDFYICVNGSSENKPIRSSYFTFQLQNIVKPLPPVYLTF-TRESSCEIKL 256
L +++++ VNG+S I+ + I + PP +T + C ++
Sbjct: 179 HLDNLSGLTSRNYFL-VNGTSREIGIQFFDSLLDTKKIERFNPPSNVTVRCNTTHCLVRW 237
Query: 257 KWSIPLGPIPARCFDYEIEIREDDT------TLVTATVENETYTLKTTNETRQLCFVVRS 310
K + F Y++++ +T L+ + + E ++E R +
Sbjct: 238 KQPRTYQKLSYLDFQYQLDVHRKNTQPGTENLLINVSGDLENRYNFPSSEPR-----AKH 292
Query: 311 KVNIYCSDDGI--WSEWSD 327
V I +D I WS WS+
Sbjct: 293 SVKIRAADVRILNWSSWSE 311
>gi|4758062 cytokine receptor-like factor 1 [Homo sapiens]
Length = 422
Score = 50.1 bits (118), Expect = 3e-06
Identities = 59/209 (28%), Positives = 90/209 (43%), Gaps = 25/209 (11%)
Query: 134 GIPETKVQDMDCVYYNWQYLLCSWKPGI--GVLLDTNYNLFY---WYEGLDHALQCVDYI 188
G+P K ++ C N + L C W PG L TNY+L Y WY G D+ C +Y
Sbjct: 132 GLPPEKPVNISCWSKNMKDLTCRWTPGAHGETFLHTNYSLKYKLRWY-GQDNT--CEEYH 188
Query: 189 KADGQNIGCRFPYLEASDYKDFYICVNGSSENKPIRSSYFTFQLQNIVKPLPPVYLTFTR 248
+ C P + + + + I V ++ RS T + ++V PP + +R
Sbjct: 189 TVGPHS--CHIP-KDLALFTPYEIWVEATNRLGSARSDVLTLDILDVVTTDPPPDVHVSR 245
Query: 249 ESSCE--IKLKWSIPLGPIPARCF----DYEIEIREDDTT--LVTATVENETYTLKTTNE 300
E + ++W + P + F Y+I R +D+ V V N+T +
Sbjct: 246 VGGLEDQLSVRW---VSPPALKDFLFQAKYQIRYRVEDSVDWKVVDDVSNQTSCRLAGLK 302
Query: 301 TRQLCFV-VR-SKVNIYCSDD-GIWSEWS 326
+ FV VR + IY S GIWSEWS
Sbjct: 303 PGTVYFVQVRCNPFGIYGSKKAGIWSEWS 331
>gi|4504643 interleukin 12 receptor, beta 2 precursor [Homo sapiens]
Length = 862
Score = 47.0 bits (110), Expect = 3e-05
Identities = 58/226 (25%), Positives = 92/226 (40%), Gaps = 31/226 (13%)
Query: 113 CTNGSEVQSSWAETTYWISPQGIPETKVQDMDCVYYNWQ-YLLCSWKPGIGVLLDTNYNL 171
C N E+Q AE ++P+ + Q++ C+ Q + C+W+ G L T Y L
Sbjct: 105 CINSDEIQICGAEIFVGVAPE-----QPQNLSCIQKGEQGTVACTWERGRDTHLYTEYTL 159
Query: 172 -FYWYEGLDHALQCVDYIKADGQNIGCRF-PYLEASDYKDFYICVN--GSSENKPIRSSY 227
+ L QC D I D + G P S++ VN GSS + P
Sbjct: 160 QLSGPKNLTWQKQCKD-IYCDYLDFGINLTPESPESNFTAKVTAVNSLGSSSSLPS---- 214
Query: 228 FTFQLQNIVKPLPP--VYLTFTRESSCEIKLKWS----IPLGPIPARCFDYEIEIREDDT 281
TF +IV+PLPP + + F + S L W + L + R + +
Sbjct: 215 -TFTFLDIVRPLPPWDIRIKFQKASVSRCTLYWRDEGLVLLNRLRYRPSNSRL------W 267
Query: 282 TLVTATVENETYTLKTTNETRQLCFVVRSKVNIYCSDDGIWSEWSD 327
+V T + L + F + SK+++Y G WS+WS+
Sbjct: 268 NMVNVTKAKGRHDLLDLKPFTEYEFQISSKLHLY---KGSWSDWSE 310
>gi|13324710 interleukin 3 receptor, alpha precursor [Homo sapiens]
Length = 378
Score = 46.6 bits (109), Expect = 4e-05
Identities = 61/248 (24%), Positives = 99/248 (39%), Gaps = 30/248 (12%)
Query: 126 TTYWISPQ--GIPETKVQDMDCVYYNWQYLLCSWKPGIGVLLDTNYNLFYWYEGLDHALQ 183
+T+ + P+ G P +++ C ++ +L CSW G G D Y+L+ +
Sbjct: 91 STWILFPENSGKPWAGAENLTCWIHDVDFLSCSWAVGPGAPADVQYDLYLNVANRRQQYE 150
Query: 184 CVDY-IKADGQNIGCRFPYLE--ASDYKDFYICVNGSSE--NKPIRSSYFTFQLQNIVKP 238
C+ Y A G IGCRF + +S + +I V G S P + F I+ P
Sbjct: 151 CLHYKTDAQGTRIGCRFDDISRLSSGSQSSHILVRGRSAAFGIPCTDKFVVFSQIEILTP 210
Query: 239 LPPVYLTFTRESSCEIKLKWSIPLGPIPARCFDYEIEIREDDTTLVTATVENET--YTLK 296
S K++ R F YE++I++ ++T V + T L
Sbjct: 211 PNMTAKCNKTHSFMHWKMRSHF------NRKFRYELQIQKRMQPVITEQVRDRTSFQLLN 264
Query: 297 TTNETRQLCFVVRSKVNIYCSDDGIWSEWSDKQCWEGEDLSKKTLLRFW-----LPFGFI 351
T Q +R++ +Y S WS Q +E D + R W + G +
Sbjct: 265 PGTYTVQ----IRARERVY----EFLSAWSTPQRFEC-DQEEGANTRAWRTSLLIALGTL 315
Query: 352 LILV-IFV 358
L LV +FV
Sbjct: 316 LALVCVFV 323
>gi|4504993 leukemia inhibitory factor receptor precursor [Homo
sapiens]
Length = 1097
Score = 43.5 bits (101), Expect = 3e-04
Identities = 56/242 (23%), Positives = 91/242 (37%), Gaps = 41/242 (16%)
Query: 134 GIPETKVQDMDCVYYNWQYLLCSWKPGIGVLL----DTNYNLFYWYEGLDHALQCVDYIK 189
G P Q ++C ++ + ++CSW PG L T+Y L + G L+ +
Sbjct: 330 GYPPDTPQQLNCETHDLKEIICSWNPGRVTALVGPRATSYTLVESFSGKYVRLKRAE--A 387
Query: 190 ADGQNIGCRFPYLEASDYKDFYICVNGSSENKPIRSSYFTFQLQNI---VKPLPPVYLTF 246
++ F L + +F + + + P+ S T L NI V P P
Sbjct: 388 PTNESYQLLFQMLPNQEIYNFTL-----NAHNPLGRSQSTI-LVNITEKVYPHTPTSFKV 441
Query: 247 TRESSCEIKLKWSIPLGPIPARCFDYEIEIR-----EDDTTLVTATVENETYTLKTTNET 301
+S +KL W +P G F EIEI+ ++ + VEN +Y +
Sbjct: 442 KDINSTAVKLSWHLP-GNFAKINFLCEIEIKKSNSVQEQRNVTIKGVENSSYLVALDKLN 500
Query: 302 RQLCFVVRSKVNIYCSDDGI--WSEWSDKQ--------------CWEGEDLSKKTLLRFW 345
+ R I CS + WS+WS+K+ W K L+ +W
Sbjct: 501 PYTLYTFR----IRCSTETFWKWSKWSNKKQHLTTEASPSKGPDTWREWSSDGKNLIIYW 556
Query: 346 LP 347
P
Sbjct: 557 KP 558
Score = 35.0 bits (79), Expect = 0.11
Identities = 49/201 (24%), Positives = 81/201 (40%), Gaps = 29/201 (14%)
Query: 142 DMDCVYYNWQYLLCSWKPGIGVLLDTNYNLFYWYEGLDHALQCVDYIKADGQNIGCRFPY 201
D+ CV N Q CSWK G T+Y + C++ +
Sbjct: 52 DLKCVTNNLQVWNCSWKAPSGTGRGTDYEV------------CIENRSRSCYQLEKTSIK 99
Query: 202 LEASDYKDFYICVNGSSENKPIRSSYFTFQLQNI-VKPLPPVYLTFTRE-SSCEIKLKWS 259
+ A + D+ I +N S + +S FT QN+ + P P L + + S+ + LKW+
Sbjct: 100 IPALSHGDYEITIN-SLHDFGSSTSKFTLNEQNVSLIPDTPEILNLSADFSTSTLYLKWN 158
Query: 260 IPLGPIPARC-FDYEIEI-REDDTTLVTATVENETYTLKTT-------NETRQLCFV--- 307
P R +EI++ R++ LV N T K T ++ C +
Sbjct: 159 DRGSVFPHRSNVIWEIKVLRKESMELVKLVTHNTTLNGKDTLHHWSWASDMPLECAIHFV 218
Query: 308 -VRSKV-NIYCSDDGIWSEWS 326
+R + N++ S WS+WS
Sbjct: 219 EIRCYIDNLHFSGLEEWSDWS 239
>gi|189083786 leukemia inhibitory factor receptor precursor [Homo
sapiens]
Length = 1097
Score = 43.5 bits (101), Expect = 3e-04
Identities = 56/242 (23%), Positives = 91/242 (37%), Gaps = 41/242 (16%)
Query: 134 GIPETKVQDMDCVYYNWQYLLCSWKPGIGVLL----DTNYNLFYWYEGLDHALQCVDYIK 189
G P Q ++C ++ + ++CSW PG L T+Y L + G L+ +
Sbjct: 330 GYPPDTPQQLNCETHDLKEIICSWNPGRVTALVGPRATSYTLVESFSGKYVRLKRAE--A 387
Query: 190 ADGQNIGCRFPYLEASDYKDFYICVNGSSENKPIRSSYFTFQLQNI---VKPLPPVYLTF 246
++ F L + +F + + + P+ S T L NI V P P
Sbjct: 388 PTNESYQLLFQMLPNQEIYNFTL-----NAHNPLGRSQSTI-LVNITEKVYPHTPTSFKV 441
Query: 247 TRESSCEIKLKWSIPLGPIPARCFDYEIEIR-----EDDTTLVTATVENETYTLKTTNET 301
+S +KL W +P G F EIEI+ ++ + VEN +Y +
Sbjct: 442 KDINSTAVKLSWHLP-GNFAKINFLCEIEIKKSNSVQEQRNVTIKGVENSSYLVALDKLN 500
Query: 302 RQLCFVVRSKVNIYCSDDGI--WSEWSDKQ--------------CWEGEDLSKKTLLRFW 345
+ R I CS + WS+WS+K+ W K L+ +W
Sbjct: 501 PYTLYTFR----IRCSTETFWKWSKWSNKKQHLTTEASPSKGPDTWREWSSDGKNLIIYW 556
Query: 346 LP 347
P
Sbjct: 557 KP 558
Score = 35.0 bits (79), Expect = 0.11
Identities = 49/201 (24%), Positives = 81/201 (40%), Gaps = 29/201 (14%)
Query: 142 DMDCVYYNWQYLLCSWKPGIGVLLDTNYNLFYWYEGLDHALQCVDYIKADGQNIGCRFPY 201
D+ CV N Q CSWK G T+Y + C++ +
Sbjct: 52 DLKCVTNNLQVWNCSWKAPSGTGRGTDYEV------------CIENRSRSCYQLEKTSIK 99
Query: 202 LEASDYKDFYICVNGSSENKPIRSSYFTFQLQNI-VKPLPPVYLTFTRE-SSCEIKLKWS 259
+ A + D+ I +N S + +S FT QN+ + P P L + + S+ + LKW+
Sbjct: 100 IPALSHGDYEITIN-SLHDFGSSTSKFTLNEQNVSLIPDTPEILNLSADFSTSTLYLKWN 158
Query: 260 IPLGPIPARC-FDYEIEI-REDDTTLVTATVENETYTLKTT-------NETRQLCFV--- 307
P R +EI++ R++ LV N T K T ++ C +
Sbjct: 159 DRGSVFPHRSNVIWEIKVLRKESMELVKLVTHNTTLNGKDTLHHWSWASDMPLECAIHFV 218
Query: 308 -VRSKV-NIYCSDDGIWSEWS 326
+R + N++ S WS+WS
Sbjct: 219 EIRCYIDNLHFSGLEEWSDWS 239
>gi|115430248 gp130-like monocyte receptor [Homo sapiens]
Length = 764
Score = 43.5 bits (101), Expect = 3e-04
Identities = 44/201 (21%), Positives = 77/201 (38%), Gaps = 16/201 (7%)
Query: 139 KVQDMDCVYYNWQYLLCSWKPGIGVLLDTNYNLFYWYEGLDHALQCVDYIKADGQNIGCR 198
K +++ CVYY + L C+W PG T Y + Y + C C
Sbjct: 56 KPENISCVYYYRKNLTCTWSPGKETSY-TQYTVKRTYAFGEKHDNCTTNSSTSENRASCS 114
Query: 199 FPYLEASDYKDFYICVNGSSENKPIRSSYFTFQLQNIVKPLPPVYLTFTRESSCE--IKL 256
F + ++ I V + + I+S ++L+NI K PP + I++
Sbjct: 115 FFLPRITIPDNYTIEVEAENGDGVIKSHMTYWRLENIAKTEPPKIFRVKPVLGIKRMIQI 174
Query: 257 KWSIP-LGPIPARCFDYEIEIREDDTT-------LVTATVENETYTLKTTNETRQLCFVV 308
+W P L P+ + Y + R ++T +N+TY L + +
Sbjct: 175 EWIKPELAPVSSD-LKYTLRFRTVNSTSWMEVNFAKNRKDKNQTYNLTGLQPFTEYVIAL 233
Query: 309 RSKVNIYCSDDGIWSEWSDKQ 329
R V + WS+WS ++
Sbjct: 234 RCAV----KESKFWSDWSQEK 250
>gi|28610149 interleukin 6 signal transducer isoform 2 precursor
[Homo sapiens]
Length = 329
Score = 43.1 bits (100), Expect = 4e-04
Identities = 44/200 (22%), Positives = 77/200 (38%), Gaps = 11/200 (5%)
Query: 134 GIPETKVQDMDCVYYNWQYLLCSWKPGIGVLLDTNYNLFYWYEGLDHALQCVDYIKADGQ 193
G+P K +++ C+ + + C W G L+TN+ L E H + D
Sbjct: 123 GLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTL--KSEWATH--KFADCKAKRDT 178
Query: 194 NIGCRFPYLEASDYKDFYICVNGSSENKPIRSSYFTFQLQNIVKPLPPVYLTF--TRESS 251
C Y + + + V + + S + F VKP PP L+ + E S
Sbjct: 179 PTSCTVDY-STVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELS 237
Query: 252 CEIKLKWSIPLGPIPARCFDYEIEIREDDTTLVTATVENETYTLKTTNETRQLCFVVRSK 311
+KL W+ P Y I+ R D + + +T + +++ + L
Sbjct: 238 SILKLTWTNP-SIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYV 296
Query: 312 VNIYCSDD---GIWSEWSDK 328
I C + G WS+WS++
Sbjct: 297 FRIRCMKEDGKGYWSDWSEE 316
>gi|28610147 interleukin 6 signal transducer isoform 1 precursor
[Homo sapiens]
Length = 918
Score = 43.1 bits (100), Expect = 4e-04
Identities = 44/200 (22%), Positives = 77/200 (38%), Gaps = 11/200 (5%)
Query: 134 GIPETKVQDMDCVYYNWQYLLCSWKPGIGVLLDTNYNLFYWYEGLDHALQCVDYIKADGQ 193
G+P K +++ C+ + + C W G L+TN+ L E H + D
Sbjct: 123 GLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTL--KSEWATH--KFADCKAKRDT 178
Query: 194 NIGCRFPYLEASDYKDFYICVNGSSENKPIRSSYFTFQLQNIVKPLPPVYLTF--TRESS 251
C Y + + + V + + S + F VKP PP L+ + E S
Sbjct: 179 PTSCTVDY-STVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELS 237
Query: 252 CEIKLKWSIPLGPIPARCFDYEIEIREDDTTLVTATVENETYTLKTTNETRQLCFVVRSK 311
+KL W+ P Y I+ R D + + +T + +++ + L
Sbjct: 238 SILKLTWTNP-SIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYV 296
Query: 312 VNIYCSDD---GIWSEWSDK 328
I C + G WS+WS++
Sbjct: 297 FRIRCMKEDGKGYWSDWSEE 316
>gi|27437040 colony stimulating factor 2 receptor alpha chain
isoform e precursor [Homo sapiens]
Length = 233
Score = 43.1 bits (100), Expect = 4e-04
Identities = 22/81 (27%), Positives = 37/81 (45%), Gaps = 1/81 (1%)
Query: 138 TKVQDMDCVYYNWQYLLCSWKPGIGVLLDTNYNLFYWYEGLDHALQCVDYIKADGQNIGC 197
T Q+ C YN + C+W G D Y L+ ++C YI+ G ++GC
Sbjct: 119 TAAQNFSCFIYNADLMNCTWARGPTAPRDVQYFLYIRNSKRRREIRCPYYIQDSGTHVGC 178
Query: 198 RFPYLEASDYKDFYICVNGSS 218
L +++++ VNG+S
Sbjct: 179 HLDNLSGLTSRNYFL-VNGTS 198
>gi|238908521 colony stimulating factor 2 receptor alpha chain
isoform h [Homo sapiens]
Length = 267
Score = 42.0 bits (97), Expect = 0.001
Identities = 45/218 (20%), Positives = 86/218 (39%), Gaps = 25/218 (11%)
Query: 155 CSWKPGIGVLLDTNYNLFYWYEGLDHALQCVDYIKADGQNIGCRFPYLEASDYKDFYICV 214
C+W G D Y L+ ++C YI+ G ++GC L +++++ V
Sbjct: 3 CTWARGPTAPRDVQYFLYIRNSKRRREIRCPYYIQDSGTHVGCHLDNLSGLTSRNYFL-V 61
Query: 215 NGSSENKPIRSSYFTFQLQNIVKPLPPVYLTF-TRESSCEIKLKWSIPLGPIPARCFDYE 273
NG+S I+ + I + PP +T + C ++ K + F Y+
Sbjct: 62 NGTSREIGIQFFDSLLDTKKIERFNPPSNVTVRCNTTHCLVRWKQPRTYQKLSYLDFQYQ 121
Query: 274 IEIREDDT------TLVTATVENETYTLKTTNETRQLCFVVRSKVNIYCSDDGI--WSEW 325
+++ +T L+ + + E ++E R + V I +D I WS W
Sbjct: 122 LDVHRKNTQPGTENLLINVSGDLENRYNFPSSEPR-----AKHSVKIRAADVRILNWSSW 176
Query: 326 SDKQCWEGEDLSKKTLLRFWLPFGFILILVIFVTGLLL 363
S+ + +D + G + I V+ + G L+
Sbjct: 177 SEAIEFGSDDGN----------LGSVYIYVLLIVGTLV 204
>gi|51093381 leptin receptor isoform 3 [Homo sapiens]
Length = 958
Score = 41.2 bits (95), Expect = 0.002
Identities = 36/144 (25%), Positives = 59/144 (40%), Gaps = 10/144 (6%)
Query: 197 CRFPYLEASDYKDFYICVNGSSENKPIRSSYFTFQLQNIVKPLPPVYLTFTRESSCEIKL 256
C P A +C+ +S +S + Q N+VKP PP+ L +K+
Sbjct: 196 CLVPVPTAKLNDTLLMCLKITSGGVIFQSPLMSVQPINMVKPDPPLGLHMEITDDGNLKI 255
Query: 257 KWSI-PLGPIPARCFDYEIEIREDDTTLVTAT---VENETYTLKTTNETRQLCFVVRSKV 312
WS PL P P Y+++ E+ TT++ V + + + VR K
Sbjct: 256 SWSSPPLVPFP---LQYQVKYSENSTTVIREADKIVSATSLLVDSILPGSSYEVQVRGK- 311
Query: 313 NIYCSDDGIWSEWSDKQCWEGEDL 336
GIWS+WS + + +D+
Sbjct: 312 --RLDGPGIWSDWSTPRVFTTQDV 333
>gi|51093379 leptin receptor isoform 2 [Homo sapiens]
Length = 896
Score = 41.2 bits (95), Expect = 0.002
Identities = 36/144 (25%), Positives = 59/144 (40%), Gaps = 10/144 (6%)
Query: 197 CRFPYLEASDYKDFYICVNGSSENKPIRSSYFTFQLQNIVKPLPPVYLTFTRESSCEIKL 256
C P A +C+ +S +S + Q N+VKP PP+ L +K+
Sbjct: 196 CLVPVPTAKLNDTLLMCLKITSGGVIFQSPLMSVQPINMVKPDPPLGLHMEITDDGNLKI 255
Query: 257 KWSI-PLGPIPARCFDYEIEIREDDTTLVTAT---VENETYTLKTTNETRQLCFVVRSKV 312
WS PL P P Y+++ E+ TT++ V + + + VR K
Sbjct: 256 SWSSPPLVPFP---LQYQVKYSENSTTVIREADKIVSATSLLVDSILPGSSYEVQVRGK- 311
Query: 313 NIYCSDDGIWSEWSDKQCWEGEDL 336
GIWS+WS + + +D+
Sbjct: 312 --RLDGPGIWSDWSTPRVFTTQDV 333
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.140 0.462
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,277,688
Number of Sequences: 37866
Number of extensions: 745579
Number of successful extensions: 1624
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 32
Number of HSP's successfully gapped in prelim test: 24
Number of HSP's that attempted gapping in prelim test: 1369
Number of HSP's gapped (non-prelim): 242
length of query: 380
length of database: 18,247,518
effective HSP length: 104
effective length of query: 276
effective length of database: 14,309,454
effective search space: 3949409304
effective search space used: 3949409304
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.