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Search of human proteins with 100816407
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|100816407 Bardet-Biedl syndrome 10 [Homo sapiens]
(723 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|100816407 Bardet-Biedl syndrome 10 [Homo sapiens] 1448 0.0
gi|24307939 chaperonin containing TCP1, subunit 5 (epsilon) [Hom... 55 2e-07
gi|63162572 chaperonin containing TCP1, subunit 3 isoform a [Hom... 50 1e-05
gi|57863257 T-complex protein 1 isoform a [Homo sapiens] 49 1e-05
gi|58331173 chaperonin containing TCP1, subunit 6B [Homo sapiens] 49 2e-05
gi|58761486 chaperonin containing TCP1, subunit 3 isoform b [Hom... 48 3e-05
gi|5453603 chaperonin containing TCP1, subunit 2 [Homo sapiens] 47 5e-05
gi|7657253 T-complex protein 1 [Homo sapiens] 47 5e-05
gi|4502643 chaperonin containing TCP1, subunit 6A isoform a [Hom... 47 8e-05
gi|5453607 chaperonin containing TCP1, subunit 7 isoform a [Homo... 47 8e-05
gi|38455427 chaperonin containing TCP1, subunit 4 (delta) [Homo ... 45 3e-04
gi|48762932 chaperonin containing TCP1, subunit 8 (theta) [Homo ... 39 0.017
gi|9055272 McKusick-Kaufman syndrome protein [Homo sapiens] 39 0.022
gi|25914754 McKusick-Kaufman syndrome protein [Homo sapiens] 39 0.022
gi|37595548 phosphoinositol 3-phosphate-binding protein-3 [Homo ... 34 0.54
gi|41399285 chaperonin [Homo sapiens] 33 1.2
gi|31542947 chaperonin [Homo sapiens] 33 1.2
gi|126090663 zinc finger homeodomain 4 [Homo sapiens] 32 2.7
gi|57863259 T-complex protein 1 isoform b [Homo sapiens] 32 2.7
gi|21361745 spermatid perinuclear RNA binding protein [Homo sapi... 32 2.7
gi|57242761 receptor (TNFRSF)-interacting serine-threonine kinas... 31 4.6
gi|169211436 PREDICTED: hypothetical protein [Homo sapiens] 30 6.0
>gi|100816407 Bardet-Biedl syndrome 10 [Homo sapiens]
Length = 723
Score = 1448 bits (3748), Expect = 0.0
Identities = 723/723 (100%), Positives = 723/723 (100%)
Query: 1 MLSSMAAAGSVKAALQVAEVLEAIVSCCVGPEGRQVLCTKPTGEVLLSRNGGRLLEALHL 60
MLSSMAAAGSVKAALQVAEVLEAIVSCCVGPEGRQVLCTKPTGEVLLSRNGGRLLEALHL
Sbjct: 1 MLSSMAAAGSVKAALQVAEVLEAIVSCCVGPEGRQVLCTKPTGEVLLSRNGGRLLEALHL 60
Query: 61 EHPIARMIVDCVSSHLKKTGDGAKTFIIFLCHLLRGLHAITDREKDPLMCENIQTHGRHW 120
EHPIARMIVDCVSSHLKKTGDGAKTFIIFLCHLLRGLHAITDREKDPLMCENIQTHGRHW
Sbjct: 61 EHPIARMIVDCVSSHLKKTGDGAKTFIIFLCHLLRGLHAITDREKDPLMCENIQTHGRHW 120
Query: 121 KNCSRWKFISQALLTFQTQILDGIMDQYLSRHFLSIFSSAKERTLCRSSLELLLEAYFCG 180
KNCSRWKFISQALLTFQTQILDGIMDQYLSRHFLSIFSSAKERTLCRSSLELLLEAYFCG
Sbjct: 121 KNCSRWKFISQALLTFQTQILDGIMDQYLSRHFLSIFSSAKERTLCRSSLELLLEAYFCG 180
Query: 181 RVGRNNHKFISQLMCDYFFKCMTCKSGIGVFELVDDHFVELNVGVTGLPVSDSRIIAGLV 240
RVGRNNHKFISQLMCDYFFKCMTCKSGIGVFELVDDHFVELNVGVTGLPVSDSRIIAGLV
Sbjct: 181 RVGRNNHKFISQLMCDYFFKCMTCKSGIGVFELVDDHFVELNVGVTGLPVSDSRIIAGLV 240
Query: 241 LQKDFSVYRPADGDMRMVIVTETIQPLFSTSGSEFILNSEAQFQTSQFWIMEKTKAIMKH 300
LQKDFSVYRPADGDMRMVIVTETIQPLFSTSGSEFILNSEAQFQTSQFWIMEKTKAIMKH
Sbjct: 241 LQKDFSVYRPADGDMRMVIVTETIQPLFSTSGSEFILNSEAQFQTSQFWIMEKTKAIMKH 300
Query: 301 LHSQNVKLLISSVKQPDLVSYYAGVNGISVVECLSSEEVSLIRRIIGLSPFVPPQAFSQC 360
LHSQNVKLLISSVKQPDLVSYYAGVNGISVVECLSSEEVSLIRRIIGLSPFVPPQAFSQC
Sbjct: 301 LHSQNVKLLISSVKQPDLVSYYAGVNGISVVECLSSEEVSLIRRIIGLSPFVPPQAFSQC 360
Query: 361 EIPNTALVKFCKPLILRSKRYVHLGLISTCAFIPHSIVLCGPVHGLIEQHEDALHGALKM 420
EIPNTALVKFCKPLILRSKRYVHLGLISTCAFIPHSIVLCGPVHGLIEQHEDALHGALKM
Sbjct: 361 EIPNTALVKFCKPLILRSKRYVHLGLISTCAFIPHSIVLCGPVHGLIEQHEDALHGALKM 420
Query: 421 LRQLFKDLDLNYMTQTNDQNGTSSLFIYKNSGESYQAPDPGNGSIQRPYQDTVAENKDAL 480
LRQLFKDLDLNYMTQTNDQNGTSSLFIYKNSGESYQAPDPGNGSIQRPYQDTVAENKDAL
Sbjct: 421 LRQLFKDLDLNYMTQTNDQNGTSSLFIYKNSGESYQAPDPGNGSIQRPYQDTVAENKDAL 480
Query: 481 EKTQTYLKVHSNLVIPDVELETYIPYSTPTLTPTDTFQTVETLTCLSLERNRLTDYYEPL 540
EKTQTYLKVHSNLVIPDVELETYIPYSTPTLTPTDTFQTVETLTCLSLERNRLTDYYEPL
Sbjct: 481 EKTQTYLKVHSNLVIPDVELETYIPYSTPTLTPTDTFQTVETLTCLSLERNRLTDYYEPL 540
Query: 541 LKNNSTAYSTRGNRIEISYENLQVTNITRKGSMLPVSCKLPNMGTSQSYLSSSMPAGCVL 600
LKNNSTAYSTRGNRIEISYENLQVTNITRKGSMLPVSCKLPNMGTSQSYLSSSMPAGCVL
Sbjct: 541 LKNNSTAYSTRGNRIEISYENLQVTNITRKGSMLPVSCKLPNMGTSQSYLSSSMPAGCVL 600
Query: 601 PVGGNFEILLHYYLLNYAKKCHQSEETMVSMIIANALLGIPKVLYKSKTGKYSFPHTYIR 660
PVGGNFEILLHYYLLNYAKKCHQSEETMVSMIIANALLGIPKVLYKSKTGKYSFPHTYIR
Sbjct: 601 PVGGNFEILLHYYLLNYAKKCHQSEETMVSMIIANALLGIPKVLYKSKTGKYSFPHTYIR 660
Query: 661 AVHALQTNQPLVSSQTGLESVMGKYQLLTSVLQCLTKILTIDMVITVKRHPQKVHNQDSE 720
AVHALQTNQPLVSSQTGLESVMGKYQLLTSVLQCLTKILTIDMVITVKRHPQKVHNQDSE
Sbjct: 661 AVHALQTNQPLVSSQTGLESVMGKYQLLTSVLQCLTKILTIDMVITVKRHPQKVHNQDSE 720
Query: 721 DEL 723
DEL
Sbjct: 721 DEL 723
>gi|24307939 chaperonin containing TCP1, subunit 5 (epsilon) [Homo
sapiens]
Length = 541
Score = 55.5 bits (132), Expect = 2e-07
Identities = 80/427 (18%), Positives = 170/427 (39%), Gaps = 39/427 (9%)
Query: 3 SSMAAAGSVKAALQVAEVLEAIVSCCVGPEGRQVLCTKPTGEVLLSRNGGRLLEALHLEH 62
S + ++K+ + A+ + + +GP G + G+V ++ +G +L + ++H
Sbjct: 26 SRLMGLEALKSHIMAAKAVANTMRTSLGPNGLDKMMVDKDGDVTVTNDGATILSMMDVDH 85
Query: 63 PIARMIVDCVSSHLKKTGDGAKTFIIFLCHLLRGLHAITDREKDPLMCENIQTHGRHWKN 122
IA+++V+ S + GDG ++ LL + DR P+ + ++
Sbjct: 86 QIAKLMVELSKSQDDEIGDGTTGVVVLAGALLEEAEQLLDRGIHPIRIAD------GYEQ 139
Query: 123 CSRWKFISQALLTFQTQILDGIMDQYLSRHFLSIFSSAKERTLCRSSLELLLEAYFCGRV 182
+R + LD I D S+ K+ + + L + +V
Sbjct: 140 AAR----------VAIEHLDKISD--------SVLVDIKDTEPLIQTAKTTLGS----KV 177
Query: 183 GRNNHKFISQLMCDYFFKCMTCKSGIGVFELVDDHFVELNVGVTGLPVSDSRIIAGLVLQ 242
+ H+ ++++ + + FEL+ VE G G + D+++I G+++
Sbjct: 178 VNSCHRQMAEIAVNAVLTVADMERRDVDFELIK---VE---GKVGGRLEDTKLIKGVIVD 231
Query: 243 KDFSVYRPAD--GDMRMVIVTETIQPLFSTSGSEFILNSEAQFQTSQFWIMEKTKAIMKH 300
KDFS + D ++ I+T +P + + + S ++ Q + EK + +++
Sbjct: 232 KDFSHPQMPKKVEDAKIAILTCPFEPPKPKTKHKLDVTSVEDYKALQKYEKEKFEEMIQQ 291
Query: 301 LHSQNVKLLISSVKQPDLVSYYAGVNGISVVECLSSEEVSLIRRIIGLSPFVPPQAFSQC 360
+ L I D ++ N + V + E+ LI G VP FS+
Sbjct: 292 IKETGANLAICQWGFDDEANHLLLQNNLPAVRWVGGPEIELIAIATG-GRIVP--RFSEL 348
Query: 361 EIPNTALVKFCKPLILRSKRYVHLGLISTCAFIPHSIVLCGPVHGLIEQHEDALHGALKM 420
+ + + + L + +I + G +IE+ + +LH AL +
Sbjct: 349 TAEKLGFAGLVQEISFGTTKDKMLVIEQCKNSRAVTIFIRGGNKMIIEEAKRSLHDALCV 408
Query: 421 LRQLFKD 427
+R L +D
Sbjct: 409 IRNLIRD 415
>gi|63162572 chaperonin containing TCP1, subunit 3 isoform a [Homo
sapiens]
Length = 545
Score = 49.7 bits (117), Expect = 1e-05
Identities = 21/100 (21%), Positives = 52/100 (52%), Gaps = 4/100 (4%)
Query: 8 AGSVKAALQVAEVLEAIVSCCVGPEGRQVLCTKPTGEVLLSRNGGRLLEALHLEHPIARM 67
+G++ AA +A+++ C+GP+ + P G ++++ +G +L + ++HP A+
Sbjct: 24 SGNINAAKTIADIIRT----CLGPKSMMKMLLDPMGGIVMTNDGNAILREIQVQHPAAKS 79
Query: 68 IVDCVSSHLKKTGDGAKTFIIFLCHLLRGLHAITDREKDP 107
+++ + ++ GDG + II +L +++ P
Sbjct: 80 MIEISRTQDEEVGDGTTSVIILAGEMLSVAEHFLEQQMHP 119
>gi|57863257 T-complex protein 1 isoform a [Homo sapiens]
Length = 556
Score = 49.3 bits (116), Expect = 1e-05
Identities = 26/98 (26%), Positives = 48/98 (48%), Gaps = 4/98 (4%)
Query: 10 SVKAALQVAEVLEAIVSCCVGPEGRQVLCTKPTGEVLLSRNGGRLLEALHLEHPIARMIV 69
+V AA +A IV +GP G + G+V ++ +G +L+ L +EHP A+++
Sbjct: 21 NVMAAASIAN----IVKSSLGPVGLDKMLVDDIGDVTITNDGATILKLLEVEHPAAKVLC 76
Query: 70 DCVSSHLKKTGDGAKTFIIFLCHLLRGLHAITDREKDP 107
+ K+ GDG + +I LL+ + ++ P
Sbjct: 77 ELADLQDKEVGDGTTSVVIIAAELLKNADELVKQKIHP 114
Score = 31.6 bits (70), Expect = 2.7
Identities = 36/132 (27%), Positives = 52/132 (39%), Gaps = 21/132 (15%)
Query: 599 VLPVGGNFEILLHYYLLNYAKKCHQSEETMVSMIIANALLGIPKVLYKSKTGKYSFPHTY 658
V+P GG E L YL NYA E+ ++ A +LL IP L + +
Sbjct: 408 VVPGGGAVEAALSIYLENYATSMGSREQLAIAE-FARSLLVIPNTLAVNAAQDSTDLVAK 466
Query: 659 IRAVH-----------------ALQTNQPLVSSQTGL-ESVMGKYQLLTSVLQCLTKILT 700
+RA H L +P + Q G+ E + K + L + IL
Sbjct: 467 LRAFHNEAQVNPERKNLKWIGLDLSNGKPRDNKQAGVFEPTIVKVKSLKFATEAAITILR 526
Query: 701 IDMVITVKRHPQ 712
ID +I K HP+
Sbjct: 527 IDDLI--KLHPE 536
>gi|58331173 chaperonin containing TCP1, subunit 6B [Homo sapiens]
Length = 530
Score = 48.9 bits (115), Expect = 2e-05
Identities = 26/98 (26%), Positives = 52/98 (53%), Gaps = 4/98 (4%)
Query: 2 LSSMAAAGSVKAALQV----AEVLEAIVSCCVGPEGRQVLCTKPTGEVLLSRNGGRLLEA 57
++S A +AAL V A L+ ++ +GP+G + G++ L+++G LL+
Sbjct: 7 VNSKAEVARARAALAVNICAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDGNVLLDE 66
Query: 58 LHLEHPIARMIVDCVSSHLKKTGDGAKTFIIFLCHLLR 95
+ ++HP A +I ++ TGDG + ++ + LL+
Sbjct: 67 MQIQHPTASLIAKVATAQDDVTGDGTTSNVLIIGELLK 104
>gi|58761486 chaperonin containing TCP1, subunit 3 isoform b [Homo
sapiens]
Length = 544
Score = 48.1 bits (113), Expect = 3e-05
Identities = 19/81 (23%), Positives = 46/81 (56%), Gaps = 4/81 (4%)
Query: 8 AGSVKAALQVAEVLEAIVSCCVGPEGRQVLCTKPTGEVLLSRNGGRLLEALHLEHPIARM 67
+G++ AA +A+++ C+GP+ + P G ++++ +G +L + ++HP A+
Sbjct: 24 SGNINAAKTIADIIRT----CLGPKSMMKMLLDPMGGIVMTNDGNAILREIQVQHPAAKS 79
Query: 68 IVDCVSSHLKKTGDGAKTFII 88
+++ + ++ GDG + II
Sbjct: 80 MIEISRTQDEEVGDGTTSVII 100
>gi|5453603 chaperonin containing TCP1, subunit 2 [Homo sapiens]
Length = 535
Score = 47.4 bits (111), Expect = 5e-05
Identities = 78/414 (18%), Positives = 160/414 (38%), Gaps = 58/414 (14%)
Query: 24 IVSCCVGPEGRQ--VLCTKPTGEVLLSRNGGRLLEALHLEHPIARMIVDCVSSHLKKTGD 81
+V +GP+G +L + ++++ +G +L+ + +++P A+++VD + GD
Sbjct: 38 LVKSTLGPKGMDKILLSSGRDASLMVTNDGATILKNIGVDNPAAKVLVDMSRVQDDEVGD 97
Query: 82 GAKTFIIFLCHLLRGLHAITDREKDPLMCENIQTHGRHWKNCSRWKFISQALLTFQTQIL 141
G + + LLR ++ ++ P QT W+ + K +ALL+
Sbjct: 98 GTTSVTVLAAELLREAESLIAKKIHP------QTIIAGWREAT--KAAREALLS------ 143
Query: 142 DGIMDQYLSRHFLSIFSSAKERTLCRSSLELLLEAYFCGRVGRNNHKFISQLMCDYFFKC 201
S + R L + ++ ++ ++L + +
Sbjct: 144 -------------SAVDHGSDEVKFRQDLMNIAGTTLSSKLLTHHKDHFTKLAVEAVLRL 190
Query: 202 MTCKSGIGVFELVDDHFVELNVGVTGLPVSDSRIIAGLVLQKDFSVYRPADGDMRMVIVT 261
G G E + H ++ G ++DS + G +L K V +P + +++
Sbjct: 191 ----KGSGNLEAI--HIIKK----LGGSLADSYLDEGFLLDKKIGVNQPKRIENAKILIA 240
Query: 262 ETIQPL--FSTSGSEFILNSEAQFQTSQFWIMEKTKAIMKHLHSQNVKLLISS---VKQP 316
T GS ++S A+ + EK K ++ + + I+ P
Sbjct: 241 NTGMDTDKIKIFGSRVRVDSTAKVAEIEHAEKEKMKEKVERILKHGINCFINRQLIYNYP 300
Query: 317 DLVSYYAGVNGISVVECLSSEEVSLIRRIIGLSPFVPPQAFSQCEIPNTALVKFCKPLIL 376
+ + AGV I + E ++L+ S F P E+ K + +++
Sbjct: 301 EQLFGAAGVMAIEHADFAGVERLALVTGGEIASTFDHP------ELVKLGSCKLIEEVMI 354
Query: 377 RSKRYVH---LGLISTCAFIPHSIVLCGPVHGLIEQHEDALHGALKMLRQLFKD 427
+ +H + L C +IVL G ++++ E +LH AL +L Q KD
Sbjct: 355 GEDKLIHFSGVALGEAC-----TIVLRGATQQILDEAERSLHDALCVLAQTVKD 403
>gi|7657253 T-complex protein 1 [Homo sapiens]
Length = 557
Score = 47.4 bits (111), Expect = 5e-05
Identities = 24/82 (29%), Positives = 41/82 (50%), Gaps = 1/82 (1%)
Query: 13 AALQVAEVLEAIVSCCVGPEGRQVLCTKPTGEVLLSRNGGRLLEALHLEHPIARMIVDCV 72
++L + L +++ C GP GRQ GE + + +L AL LEHP A ++ +
Sbjct: 35 SSLAAVQTLASVIRPCYGPHGRQKFLVTMKGETVCTGCATAILRALELEHPAAWLLREAG 94
Query: 73 SSHLKKTGDGAKTFIIFLCHLL 94
+ + +GDG F++ L L
Sbjct: 95 QTQAENSGDGT-AFVVLLTEAL 115
>gi|4502643 chaperonin containing TCP1, subunit 6A isoform a [Homo
sapiens]
Length = 531
Score = 46.6 bits (109), Expect = 8e-05
Identities = 26/98 (26%), Positives = 50/98 (51%), Gaps = 4/98 (4%)
Query: 2 LSSMAAAGSVKAALQV----AEVLEAIVSCCVGPEGRQVLCTKPTGEVLLSRNGGRLLEA 57
L+ A +AAL V A L+ ++ +GP+G + G++ L+++G LL
Sbjct: 7 LNPKAEVARAQAALAVNISAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDGNVLLHE 66
Query: 58 LHLEHPIARMIVDCVSSHLKKTGDGAKTFIIFLCHLLR 95
+ ++HP A +I ++ TGDG + ++ + LL+
Sbjct: 67 MQIQHPTASLIAKVATAQDDITGDGTTSNVLIIGELLK 104
>gi|5453607 chaperonin containing TCP1, subunit 7 isoform a [Homo
sapiens]
Length = 543
Score = 46.6 bits (109), Expect = 8e-05
Identities = 81/427 (18%), Positives = 155/427 (36%), Gaps = 64/427 (14%)
Query: 15 LQVAEVLEAIVSCCVGPEGRQVLCTKPTGEVLLSRNGGRLLEALHLEHPIARMIVDCVSS 74
+ +V+ V +GP G L G+ +S +G +L+ L + HP A+ +VD S
Sbjct: 26 ISACQVIAEAVRTTLGPRGMDKLIVDGRGKATISNDGATILKLLDVVHPAAKTLVDIAKS 85
Query: 75 HLKKTGDGAKTFIIFLCHLLRGLHAITDREKDPLMCENIQTHGRHWKNCSRWKFISQALL 134
+ GDG + + L+ + + P + I +A
Sbjct: 86 QDAEVGDGTTSVTLLAAEFLKQVKPYVEEGLHP-------------------QIIIRAFR 126
Query: 135 TFQTQILDGIMDQYLSRHFLSIFSSAKERTLCRSSLELLLEAYFCGRVGRNNHKFISQLM 194
T ++ I + +++ ++ R LE C ++ K ISQ
Sbjct: 127 TATQLAVNKIKE-------IAVTVKKADKVEQRKLLEK------CAMTALSS-KLISQQ- 171
Query: 195 CDYFFKCMTCKSGIGVFELVDDHFVELNVG---VTGLPVSDSRIIAGLVLQKDFSVYRPA 251
K K + ++DD +G V G + DS+++AG+ +K FS A
Sbjct: 172 -----KAFFAKMVVDAVMMLDDLLQLKMIGIKKVQGGALEDSQLVAGVAFKKTFSY---A 223
Query: 252 DGDMRMVIVTETIQPLFSTSGSEFILNSEAQFQTSQFWIMEKTKAI-----------MKH 300
+M+ + P + E L +E + +E +AI ++
Sbjct: 224 GFEMQ---PKKYHNPKIALLNVELELKAEKDNAEIRVHTVEDYQAIVDAEWNILYDKLEK 280
Query: 301 LHSQNVKLLISSVKQPDLVSYYAGVNGISVVECLSSEEVSLIRRIIGLSPFVPPQAFSQC 360
+H K+++S + D+ + Y + + E++ G S A S
Sbjct: 281 IHHSGAKVVLSKLPIGDVATQYFADRDMFCAGRVPEEDLKRTMMACGGSIQTSVNALSAD 340
Query: 361 EIPNTALVKFCKPLILRSKRYVHLGLISTCAFIPHSIVLCGPVHGLIEQHEDALHGALKM 420
+ + + + R + TC FI L G +E+ E +LH A+ +
Sbjct: 341 VLGRCQVFEETQIGGERYNFFTGCPKAKTCTFI-----LRGGAEQFMEETERSLHDAIMI 395
Query: 421 LRQLFKD 427
+R+ K+
Sbjct: 396 VRRAIKN 402
>gi|38455427 chaperonin containing TCP1, subunit 4 (delta) [Homo
sapiens]
Length = 539
Score = 44.7 bits (104), Expect = 3e-04
Identities = 90/429 (20%), Positives = 169/429 (39%), Gaps = 60/429 (13%)
Query: 10 SVKAALQVAEVLEAIVSCCVGPEGRQVLCTKPTGEVLLSRNGGRLLEALHLEHPIARMIV 69
++ AA VA+ + +GP+G + G+V ++ +G +L+ + + HP ARM+V
Sbjct: 37 NISAAKAVADAIRT----SLGPKGMDKMIQDGKGDVTITNDGATILKQMQVLHPAARMLV 92
Query: 70 DCVSSHLKKTGDGAKTFIIFLCHLLRGLHAITDREKDPLMCENIQTHGRHWKNCSRWKFI 129
+ + + GDG + +I LL C + G H S
Sbjct: 93 ELSKAQDIEAGDGTTSVVIIAGSLLDS-------------CTKLLQKGIHPTIISE---- 135
Query: 130 SQALLTFQTQILDGIMDQYLSRHFLSIFSSAKERTLCRSSLELLLEAYFCGRVGRNNHKF 189
+FQ + GI + L+ + S +E L ++ L N K
Sbjct: 136 -----SFQKALEKGI--EILTDMSRPVELSDRETLLNSATTSL-------------NSKV 175
Query: 190 ISQLMCDYFFKCMTCKSGIGVFELVDDHFVELN----VGVTGLPVSDSRIIAGLVL-QKD 244
+SQ M+ + + V + V+L V G + D ++ GLVL QK
Sbjct: 176 VSQY--SSLLSPMSVNAVMKVIDPATATSVDLRDIKIVKKLGGTIDDCELVEGLVLTQKV 233
Query: 245 FSVYRPADGDMRMVIVTETIQPLFSTSGSEFILNSEAQ----FQTSQFWIMEKTKAIMKH 300
+ ++ ++ + + ++ +++ AQ + + +I+ K I K
Sbjct: 234 SNSGITRVEKAKIGLIQFCLSAPKTDMDNQIVVSDYAQMDRVLREERAYILNLVKQIKK- 292
Query: 301 LHSQNVKLLISSVKQ---PDLVSYYAGVNGISVVECLSSEEVSLIRRIIGLSPFVPPQAF 357
NV L+ S+ + DL ++ I V++ + E++ I + IG P F
Sbjct: 293 -TGCNVLLIQKSILRDALSDLALHFLNKMKIMVIKDIEREDIEFICKTIGTKPVAHIDQF 351
Query: 358 SQCEIPNTALVKFCKPLILRSKRYVHLGLISTCAFIPHSIVLCGPVHGLIEQHEDALHGA 417
+ + + L + L K G S + +IV+ G +IE+ E ++H A
Sbjct: 352 TADMLGSAELAEEVN-LNGSGKLLKITGCASPGKTV--TIVVRGSNKLVIEEAERSIHDA 408
Query: 418 LKMLRQLFK 426
L ++R L K
Sbjct: 409 LCVIRCLVK 417
>gi|48762932 chaperonin containing TCP1, subunit 8 (theta) [Homo
sapiens]
Length = 548
Score = 38.9 bits (89), Expect = 0.017
Identities = 76/432 (17%), Positives = 154/432 (35%), Gaps = 78/432 (18%)
Query: 15 LQVAEVLEAIVSCCVGPEGRQVLCTKPTGEVLLSRNGGRLLEALHLEHPIARMIVDCVSS 74
+Q + L GP G + ++ ++ + +L L ++HP A+MIV
Sbjct: 33 IQACKELAQTTRTAYGPNGMNKMVINHLEKLFVTNDAATILRELEVQHPAAKMIVMASHM 92
Query: 75 HLKKTGDGAKTFIIFLCHLLRGLHAITDREKDPLMCENIQTHGRHWKNCSRWKFISQALL 134
++ GDG ++F LL +++ LL
Sbjct: 93 QEQEVGDGTNFVLVFAGALLE---------------------------------LAEELL 119
Query: 135 TFQTQILDGIMDQYLSRHFLSIFSSAKERTLCRSSLELLLEAYFCGRVGRNNHKFISQLM 194
+ + +++ Y CR + E+L C + +S L+
Sbjct: 120 RIGLSVSE-VIEGY--------------EIACRKAHEILPNLVCCSAKNLRDIDEVSSLL 164
Query: 195 ----------CDYFFKCMTCKSGIGVFELVDDHFVELNVGV---TGLPVSDSRIIAGLVL 241
+ F + ++ + +F HF N+ V G +S S ++ G+V
Sbjct: 165 RTSIMSKQYGNEVFLAKLIAQACVSIFP-DSGHFNVDNIRVCKILGSGISSSSVLHGMVF 223
Query: 242 QKDFSVYRPADGDMRMVIVTETIQPLFS-TSGSEFILNSE--AQFQTSQFWIMEKTKAIM 298
+K+ + D ++ + + + + T G+ I +E F + +M+ A +
Sbjct: 224 KKETEGDVTSVKDAKIAVYSCPFDGMITETKGTVLIKTAEELMNFSKGEENLMD---AQV 280
Query: 299 KHLHSQNVKLLISSVKQPDLVSYYAGVNGISVVECLSSEEVSLIRRIIG---LSPFVPPQ 355
K + ++++ K D+ +YA I +V S ++ + + +G L PP
Sbjct: 281 KAIADTGANVVVTGGKVADMALHYANKYNIMLVRLNSKWDLRRLCKTVGATALPRLTPPV 340
Query: 356 AFSQCEIPNTALVKFCKPLILRSKRYVHLGLISTCAFIPHSIVLCGPVHGLIEQHEDALH 415
+ L + ++ K G IST IVL G L++ E A+
Sbjct: 341 LEEMGHCDSVYLSEVGDTQVVVFKHEKEDGAIST-------IVLRGSTDNLMDDIERAVD 393
Query: 416 GALKMLRQLFKD 427
+ + L +D
Sbjct: 394 DGVNTFKVLTRD 405
>gi|9055272 McKusick-Kaufman syndrome protein [Homo sapiens]
Length = 570
Score = 38.5 bits (88), Expect = 0.022
Identities = 23/82 (28%), Positives = 38/82 (46%), Gaps = 1/82 (1%)
Query: 20 VLEAIVSCCVGPEGR-QVLCTKPTGEVLLSRNGGRLLEALHLEHPIARMIVDCVSSHLKK 78
VL+ IV+ C GP GR + L G V + LL L + HPI +++ + +H+
Sbjct: 28 VLKRIVTSCYGPSGRLKQLHNGFGGYVCTTSQSSALLSHLLVTHPILKILTASIQNHVSS 87
Query: 79 TGDGAKTFIIFLCHLLRGLHAI 100
D I C+L+ + +
Sbjct: 88 FSDCGLFTAILCCNLIENVQRL 109
>gi|25914754 McKusick-Kaufman syndrome protein [Homo sapiens]
Length = 570
Score = 38.5 bits (88), Expect = 0.022
Identities = 23/82 (28%), Positives = 38/82 (46%), Gaps = 1/82 (1%)
Query: 20 VLEAIVSCCVGPEGR-QVLCTKPTGEVLLSRNGGRLLEALHLEHPIARMIVDCVSSHLKK 78
VL+ IV+ C GP GR + L G V + LL L + HPI +++ + +H+
Sbjct: 28 VLKRIVTSCYGPSGRLKQLHNGFGGYVCTTSQSSALLSHLLVTHPILKILTASIQNHVSS 87
Query: 79 TGDGAKTFIIFLCHLLRGLHAI 100
D I C+L+ + +
Sbjct: 88 FSDCGLFTAILCCNLIENVQRL 109
>gi|37595548 phosphoinositol 3-phosphate-binding protein-3 [Homo
sapiens]
Length = 1048
Score = 33.9 bits (76), Expect = 0.54
Identities = 43/168 (25%), Positives = 71/168 (42%), Gaps = 23/168 (13%)
Query: 450 NSGESYQAPDPGNGSIQRPYQDTVAENKDALEKTQTYLKVHSNLVIPDVEL--ETYIPYS 507
N + +A +PG + + P ++ K LE + ++ L PD L E YI
Sbjct: 875 NLEAALRAEEPGGHAYETPREEIARLRKMELEPQHYDVDINKELSTPDKVLIPERYIDLE 934
Query: 508 TPT-LTPTDT------FQTVETLTCLSLERNRLT----DYYEPLLKNNSTAYSTRGNRIE 556
T L+P + + ++TL S +N + D + + +++ + + RIE
Sbjct: 935 PDTPLSPEELKEKQKKVERIKTLIAKSSMQNVVPIGEGDSVD-VPQDSESQLQEQEKRIE 993
Query: 557 ISYENLQVTNITRKGSMLPVSCKLPNMGTSQSY-------LSSSMPAG 597
IS T +R+G ML V C P+ TS + LSS P G
Sbjct: 994 ISCA--LATEASRRGRMLSVQCATPSPPTSPASPAPPANPLSSESPRG 1039
>gi|41399285 chaperonin [Homo sapiens]
Length = 573
Score = 32.7 bits (73), Expect = 1.2
Identities = 18/75 (24%), Positives = 41/75 (54%), Gaps = 4/75 (5%)
Query: 15 LQVAEVLEAIVSCCVGPEGRQVLCTKPTGEVLLSRNGGRLLEALHLEHPI----ARMIVD 70
LQ ++L V+ +GP+GR V+ + G ++++G + +++ L+ A+++ D
Sbjct: 41 LQGVDLLADAVAVTMGPKGRTVIIEQSWGSPKVTKDGVTVAKSIDLKDKYKNIGAKLVQD 100
Query: 71 CVSSHLKKTGDGAKT 85
++ ++ GDG T
Sbjct: 101 VANNTNEEAGDGTTT 115
>gi|31542947 chaperonin [Homo sapiens]
Length = 573
Score = 32.7 bits (73), Expect = 1.2
Identities = 18/75 (24%), Positives = 41/75 (54%), Gaps = 4/75 (5%)
Query: 15 LQVAEVLEAIVSCCVGPEGRQVLCTKPTGEVLLSRNGGRLLEALHLEHPI----ARMIVD 70
LQ ++L V+ +GP+GR V+ + G ++++G + +++ L+ A+++ D
Sbjct: 41 LQGVDLLADAVAVTMGPKGRTVIIEQSWGSPKVTKDGVTVAKSIDLKDKYKNIGAKLVQD 100
Query: 71 CVSSHLKKTGDGAKT 85
++ ++ GDG T
Sbjct: 101 VANNTNEEAGDGTTT 115
>gi|126090663 zinc finger homeodomain 4 [Homo sapiens]
Length = 3571
Score = 31.6 bits (70), Expect = 2.7
Identities = 26/114 (22%), Positives = 45/114 (39%), Gaps = 2/114 (1%)
Query: 392 FIPHSIVLCGPVHGLIEQHEDALHGALKMLRQLFKDLDLNYMTQTNDQNGTSSLFIYKNS 451
+IP + GP GL + G M L +DL QT G + L I +
Sbjct: 1697 YIPGTEFSLGPDLGLPGSATFGMPGMTGMAGSLLEDL--KQQIQTQHHVGQTQLQILQQQ 1754
Query: 452 GESYQAPDPGNGSIQRPYQDTVAENKDALEKTQTYLKVHSNLVIPDVELETYIP 505
+ YQA P ++ Q + + + ++ + SN+V D ++ +P
Sbjct: 1755 AQQYQATQPQLQPQKQQQQPPPPQQQQQQQASKLLKQEQSNIVSADCQIMKDVP 1808
>gi|57863259 T-complex protein 1 isoform b [Homo sapiens]
Length = 401
Score = 31.6 bits (70), Expect = 2.7
Identities = 36/132 (27%), Positives = 52/132 (39%), Gaps = 21/132 (15%)
Query: 599 VLPVGGNFEILLHYYLLNYAKKCHQSEETMVSMIIANALLGIPKVLYKSKTGKYSFPHTY 658
V+P GG E L YL NYA E+ ++ A +LL IP L + +
Sbjct: 253 VVPGGGAVEAALSIYLENYATSMGSREQLAIAE-FARSLLVIPNTLAVNAAQDSTDLVAK 311
Query: 659 IRAVH-----------------ALQTNQPLVSSQTGL-ESVMGKYQLLTSVLQCLTKILT 700
+RA H L +P + Q G+ E + K + L + IL
Sbjct: 312 LRAFHNEAQVNPERKNLKWIGLDLSNGKPRDNKQAGVFEPTIVKVKSLKFATEAAITILR 371
Query: 701 IDMVITVKRHPQ 712
ID +I K HP+
Sbjct: 372 IDDLI--KLHPE 381
>gi|21361745 spermatid perinuclear RNA binding protein [Homo
sapiens]
Length = 672
Score = 31.6 bits (70), Expect = 2.7
Identities = 23/87 (26%), Positives = 42/87 (48%), Gaps = 13/87 (14%)
Query: 407 IEQHEDALHGALKMLR-----QLFKDLDLNYMTQTNDQNGTSSLFIYKNSGESYQAPDPG 461
I+Q ED H A LR Q++K L+++ + SS K S G
Sbjct: 300 IQQKEDITHSAQHALRLSAFGQIYKVLEMDPLP--------SSKPFQKYSWSVTDKEGAG 351
Query: 462 NGSIQRPYQDTVAENKDALEKTQTYLK 488
+ +++RP++D + ++KD +K + L+
Sbjct: 352 SSALKRPFEDGLGDDKDPNKKMKRNLR 378
>gi|57242761 receptor (TNFRSF)-interacting serine-threonine kinase 1
[Homo sapiens]
Length = 671
Score = 30.8 bits (68), Expect = 4.6
Identities = 13/27 (48%), Positives = 20/27 (74%), Gaps = 4/27 (14%)
Query: 99 AITDREKDPLMCENIQTHGRHWKNCSR 125
++TD+ DP+ EN+ G+HWKNC+R
Sbjct: 581 SLTDKHLDPIR-ENL---GKHWKNCAR 603
>gi|169211436 PREDICTED: hypothetical protein [Homo sapiens]
Length = 280
Score = 30.4 bits (67), Expect = 6.0
Identities = 25/96 (26%), Positives = 38/96 (39%), Gaps = 2/96 (2%)
Query: 502 TYIPYSTPTLTP--TDTFQTVETLTCLSLERNRLTDYYEPLLKNNSTAYSTRGNRIEISY 559
T P STPTLTP T T T T LT P+L +ST T + ++
Sbjct: 149 TLTPSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSTPTLTP 208
Query: 560 ENLQVTNITRKGSMLPVSCKLPNMGTSQSYLSSSMP 595
+ + +++P S ++ + SS P
Sbjct: 209 SSTPTLTPSNTPTLIPSSTPTLTPSSTPTLTPSSRP 244
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.135 0.398
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,429,213
Number of Sequences: 37866
Number of extensions: 1144370
Number of successful extensions: 2755
Number of sequences better than 10.0: 22
Number of HSP's better than 10.0 without gapping: 12
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 2707
Number of HSP's gapped (non-prelim): 54
length of query: 723
length of database: 18,247,518
effective HSP length: 110
effective length of query: 613
effective length of database: 14,082,258
effective search space: 8632424154
effective search space used: 8632424154
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.