Search of human proteins with 100816397

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|100816397 MYST histone acetyltransferase (monocytic
leukemia) 4 [Homo sapiens]
         (2073 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|100816397 MYST histone acetyltransferase (monocytic leukemia)...  4209   0.0  
gi|150378543 MYST histone acetyltransferase (monocytic leukemia)...  1384   0.0  
gi|150378463 MYST histone acetyltransferase (monocytic leukemia)...  1384   0.0  
gi|150378493 MYST histone acetyltransferase (monocytic leukemia)...  1384   0.0  
gi|5901962 MYST histone acetyltransferase 2 [Homo sapiens]            362   2e-99
gi|226371636 MYST histone acetyltransferase 1 isoform 1 [Homo sa...   290   8e-78
gi|226371638 MYST histone acetyltransferase 1 isoform 2 [Homo sa...   285   3e-76
gi|36287069 K(lysine) acetyltransferase 5 isoform 1 [Homo sapiens]    281   4e-75
gi|36287060 K(lysine) acetyltransferase 5 isoform 3 [Homo sapiens]    281   4e-75
gi|36287049 K(lysine) acetyltransferase 5 isoform 2 [Homo sapiens]    281   4e-75
gi|5454004 D4, zinc and double PHD fingers family 2 [Homo sapiens]    135   4e-31
gi|205830434 D4, zinc and double PHD fingers family 1 isoform c ...   134   1e-30
gi|205830430 D4, zinc and double PHD fingers family 1 isoform a ...   134   1e-30
gi|205830432 D4, zinc and double PHD fingers family 1 isoform b ...   130   1e-29
gi|194328736 PHD finger protein 10 isoform b [Homo sapiens]           121   6e-27
gi|194328734 PHD finger protein 10 isoform a [Homo sapiens]           121   6e-27
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li...   102   3e-21
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]    101   7e-21
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li...    99   6e-20
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom...    96   4e-19
gi|148746195 trichohyalin [Homo sapiens]                               94   2e-18
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa...    91   2e-17
gi|155030232 proline, glutamic acid and leucine rich protein 1 [...    88   8e-17
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa...    87   2e-16
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ...    84   1e-15
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ...    84   1e-15
gi|95147555 microtubule-associated protein 1A [Homo sapiens]           83   3e-15
gi|55741709 RNA binding motif protein 25 [Homo sapiens]                82   7e-15
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ...    82   7e-15
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik...    81   1e-14

>gi|100816397 MYST histone acetyltransferase (monocytic leukemia) 4
            [Homo sapiens]
          Length = 2073

 Score = 4209 bits (10916), Expect = 0.0
 Identities = 2073/2073 (100%), Positives = 2073/2073 (100%)

Query: 1    MVKLANPLYTEWILEAIQKIKKQKQRPSEERICHAVSTSHGLDKKTVSEQLELSVQDGSV 60
            MVKLANPLYTEWILEAIQKIKKQKQRPSEERICHAVSTSHGLDKKTVSEQLELSVQDGSV
Sbjct: 1    MVKLANPLYTEWILEAIQKIKKQKQRPSEERICHAVSTSHGLDKKTVSEQLELSVQDGSV 60

Query: 61   LKVTNKGLASYKDPDNPGRFSSVKPGTFPKSAKGSRGSCNDLRNVDWNKLLRRAIEGLEE 120
            LKVTNKGLASYKDPDNPGRFSSVKPGTFPKSAKGSRGSCNDLRNVDWNKLLRRAIEGLEE
Sbjct: 61   LKVTNKGLASYKDPDNPGRFSSVKPGTFPKSAKGSRGSCNDLRNVDWNKLLRRAIEGLEE 120

Query: 121  PNGSSLKNIEKYLRSQSDLTSTTNNPAFQQRLRLGAKRAVNNGRLLKDGPQYRVNYGSLD 180
            PNGSSLKNIEKYLRSQSDLTSTTNNPAFQQRLRLGAKRAVNNGRLLKDGPQYRVNYGSLD
Sbjct: 121  PNGSSLKNIEKYLRSQSDLTSTTNNPAFQQRLRLGAKRAVNNGRLLKDGPQYRVNYGSLD 180

Query: 181  GKGAPQYPSAFPSSLPPVSLLPHEKDQPRADPIPICSFCLGTKESNREKKPEELLSCADC 240
            GKGAPQYPSAFPSSLPPVSLLPHEKDQPRADPIPICSFCLGTKESNREKKPEELLSCADC
Sbjct: 181  GKGAPQYPSAFPSSLPPVSLLPHEKDQPRADPIPICSFCLGTKESNREKKPEELLSCADC 240

Query: 241  GSSGHPSCLKFCPELTTNVKALRWQCIECKTCSACRVQGRNADNMLFCDSCDRGFHMECC 300
            GSSGHPSCLKFCPELTTNVKALRWQCIECKTCSACRVQGRNADNMLFCDSCDRGFHMECC
Sbjct: 241  GSSGHPSCLKFCPELTTNVKALRWQCIECKTCSACRVQGRNADNMLFCDSCDRGFHMECC 300

Query: 301  DPPLSRMPKGMWICQVCRPKKKGRKLLHEKAAQIKRRYAKPIGRPKNKLKQRLLSVTSDE 360
            DPPLSRMPKGMWICQVCRPKKKGRKLLHEKAAQIKRRYAKPIGRPKNKLKQRLLSVTSDE
Sbjct: 301  DPPLSRMPKGMWICQVCRPKKKGRKLLHEKAAQIKRRYAKPIGRPKNKLKQRLLSVTSDE 360

Query: 361  GSMNAFTGRGSPGRGQKTKVCTTPSSGHAASGKDSSSRLAVTDPTRPGATTKITTTSTYI 420
            GSMNAFTGRGSPGRGQKTKVCTTPSSGHAASGKDSSSRLAVTDPTRPGATTKITTTSTYI
Sbjct: 361  GSMNAFTGRGSPGRGQKTKVCTTPSSGHAASGKDSSSRLAVTDPTRPGATTKITTTSTYI 420

Query: 421  SASTLKVNKKTKGLIDGLTKFFTPSPDGRRSRGEIIDFSKHYRPRKKVSQKQSCTSHVLA 480
            SASTLKVNKKTKGLIDGLTKFFTPSPDGRRSRGEIIDFSKHYRPRKKVSQKQSCTSHVLA
Sbjct: 421  SASTLKVNKKTKGLIDGLTKFFTPSPDGRRSRGEIIDFSKHYRPRKKVSQKQSCTSHVLA 480

Query: 481  TGTTQKLKPPPSSLPPPTPISGQSPSSQKSSTATSSPSPQSSSSQCSVPSLSSLTTNSQL 540
            TGTTQKLKPPPSSLPPPTPISGQSPSSQKSSTATSSPSPQSSSSQCSVPSLSSLTTNSQL
Sbjct: 481  TGTTQKLKPPPSSLPPPTPISGQSPSSQKSSTATSSPSPQSSSSQCSVPSLSSLTTNSQL 540

Query: 541  KALFDGLSHIYTTQGQSRKKGHPSYAPPKRMRRKTELSSTAKSKAHFFGKRDIRSRFISH 600
            KALFDGLSHIYTTQGQSRKKGHPSYAPPKRMRRKTELSSTAKSKAHFFGKRDIRSRFISH
Sbjct: 541  KALFDGLSHIYTTQGQSRKKGHPSYAPPKRMRRKTELSSTAKSKAHFFGKRDIRSRFISH 600

Query: 601  SSSSSWGMARGSIFKAIAHFKRTTFLKKHRMLGRLKYKVTPQMGTPSPGKGSLTDGRIKP 660
            SSSSSWGMARGSIFKAIAHFKRTTFLKKHRMLGRLKYKVTPQMGTPSPGKGSLTDGRIKP
Sbjct: 601  SSSSSWGMARGSIFKAIAHFKRTTFLKKHRMLGRLKYKVTPQMGTPSPGKGSLTDGRIKP 660

Query: 661  DQDDDTEIKINIKQESADVNVIGNKDVVTEEDLDVFKQAQELSWEKIECESGVEDCGRYP 720
            DQDDDTEIKINIKQESADVNVIGNKDVVTEEDLDVFKQAQELSWEKIECESGVEDCGRYP
Sbjct: 661  DQDDDTEIKINIKQESADVNVIGNKDVVTEEDLDVFKQAQELSWEKIECESGVEDCGRYP 720

Query: 721  SVIEFGKYEIQTWYSSPYPQEYARLPKLYLCEFCLKYMKSKNILLRHSKKCGWFHPPANE 780
            SVIEFGKYEIQTWYSSPYPQEYARLPKLYLCEFCLKYMKSKNILLRHSKKCGWFHPPANE
Sbjct: 721  SVIEFGKYEIQTWYSSPYPQEYARLPKLYLCEFCLKYMKSKNILLRHSKKCGWFHPPANE 780

Query: 781  IYRRKDLSVFEVDGNMSKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVLTKNDEKGCHLV 840
            IYRRKDLSVFEVDGNMSKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVLTKNDEKGCHLV
Sbjct: 781  IYRRKDLSVFEVDGNMSKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVLTKNDEKGCHLV 840

Query: 841  GYFSKEKLCQQKYNVSCIMIMPQHQRQGFGRFLIDFSYLLSRREGQAGSPEKPLSDLGRL 900
            GYFSKEKLCQQKYNVSCIMIMPQHQRQGFGRFLIDFSYLLSRREGQAGSPEKPLSDLGRL
Sbjct: 841  GYFSKEKLCQQKYNVSCIMIMPQHQRQGFGRFLIDFSYLLSRREGQAGSPEKPLSDLGRL 900

Query: 901  SYLAYWKSVILEYLYHHHERHISIKAISRATGMCPHDIATTLQHLHMIDKRDGRFVIIRR 960
            SYLAYWKSVILEYLYHHHERHISIKAISRATGMCPHDIATTLQHLHMIDKRDGRFVIIRR
Sbjct: 901  SYLAYWKSVILEYLYHHHERHISIKAISRATGMCPHDIATTLQHLHMIDKRDGRFVIIRR 960

Query: 961  EKLILSHMEKLKTCSRANELDPDSLRWTPILISNAAVSEEEREAEKEAERLMEQASCWEK 1020
            EKLILSHMEKLKTCSRANELDPDSLRWTPILISNAAVSEEEREAEKEAERLMEQASCWEK
Sbjct: 961  EKLILSHMEKLKTCSRANELDPDSLRWTPILISNAAVSEEEREAEKEAERLMEQASCWEK 1020

Query: 1021 EEQEILSTRANSRQSPAKVQSKNKYLHSPESRPVTGERGQLLELSKESSEEEEEEEDEEE 1080
            EEQEILSTRANSRQSPAKVQSKNKYLHSPESRPVTGERGQLLELSKESSEEEEEEEDEEE
Sbjct: 1021 EEQEILSTRANSRQSPAKVQSKNKYLHSPESRPVTGERGQLLELSKESSEEEEEEEDEEE 1080

Query: 1081 EEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQSVAIKRKRPFVLKKKRGRKRRRI 1140
            EEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQSVAIKRKRPFVLKKKRGRKRRRI
Sbjct: 1081 EEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQSVAIKRKRPFVLKKKRGRKRRRI 1140

Query: 1141 NSSVTTETISETTEVLNEPFDNSDEERPMPQLEPTCEIEVEEDGRKPVLRKAFQHQPGKK 1200
            NSSVTTETISETTEVLNEPFDNSDEERPMPQLEPTCEIEVEEDGRKPVLRKAFQHQPGKK
Sbjct: 1141 NSSVTTETISETTEVLNEPFDNSDEERPMPQLEPTCEIEVEEDGRKPVLRKAFQHQPGKK 1200

Query: 1201 RQTEEEEGKDNHCFKNADPCRNNMNDDSSNLKEGSKDNPEPLKCKQVWPKGTKRGLSKWR 1260
            RQTEEEEGKDNHCFKNADPCRNNMNDDSSNLKEGSKDNPEPLKCKQVWPKGTKRGLSKWR
Sbjct: 1201 RQTEEEEGKDNHCFKNADPCRNNMNDDSSNLKEGSKDNPEPLKCKQVWPKGTKRGLSKWR 1260

Query: 1261 QNKERKTGFKLNLYTPPETPMEPDEQVTVEEQKETSEGKTSPSPIRIEEEVKETGEALLP 1320
            QNKERKTGFKLNLYTPPETPMEPDEQVTVEEQKETSEGKTSPSPIRIEEEVKETGEALLP
Sbjct: 1261 QNKERKTGFKLNLYTPPETPMEPDEQVTVEEQKETSEGKTSPSPIRIEEEVKETGEALLP 1320

Query: 1321 QEENRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGEEEEGGGNVEK 1380
            QEENRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGEEEEGGGNVEK
Sbjct: 1321 QEENRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGEEEEGGGNVEK 1380

Query: 1381 DPDGAKSQEKEEPEISTEKEDSARLDDHEEEEEEDEEPSHNEDHDADDEDDSHMESAEVE 1440
            DPDGAKSQEKEEPEISTEKEDSARLDDHEEEEEEDEEPSHNEDHDADDEDDSHMESAEVE
Sbjct: 1381 DPDGAKSQEKEEPEISTEKEDSARLDDHEEEEEEDEEPSHNEDHDADDEDDSHMESAEVE 1440

Query: 1441 KEELPRESFKEVLENQETFLDLNVQPGHSNPEVLMDCGVDLTASCNSEPKELAGDPEAVP 1500
            KEELPRESFKEVLENQETFLDLNVQPGHSNPEVLMDCGVDLTASCNSEPKELAGDPEAVP
Sbjct: 1441 KEELPRESFKEVLENQETFLDLNVQPGHSNPEVLMDCGVDLTASCNSEPKELAGDPEAVP 1500

Query: 1501 ESDEEPPPGEQAQKQDQKNSKEVDTEFKEGNPATMEIDSETVQAVQSLTQESSEQDDTFQ 1560
            ESDEEPPPGEQAQKQDQKNSKEVDTEFKEGNPATMEIDSETVQAVQSLTQESSEQDDTFQ
Sbjct: 1501 ESDEEPPPGEQAQKQDQKNSKEVDTEFKEGNPATMEIDSETVQAVQSLTQESSEQDDTFQ 1560

Query: 1561 DCAETQEACRSLQNYTRADQSPQIATTLDDCQQSDHSSPVSSVHSHPGQSVRSVNSPSVP 1620
            DCAETQEACRSLQNYTRADQSPQIATTLDDCQQSDHSSPVSSVHSHPGQSVRSVNSPSVP
Sbjct: 1561 DCAETQEACRSLQNYTRADQSPQIATTLDDCQQSDHSSPVSSVHSHPGQSVRSVNSPSVP 1620

Query: 1621 ALENSYAQISPDQSAISVPSLQNMETSPMMDVPSVSDHSQQVVDSGFSDLGSIESTTENY 1680
            ALENSYAQISPDQSAISVPSLQNMETSPMMDVPSVSDHSQQVVDSGFSDLGSIESTTENY
Sbjct: 1621 ALENSYAQISPDQSAISVPSLQNMETSPMMDVPSVSDHSQQVVDSGFSDLGSIESTTENY 1680

Query: 1681 ENPSSYDSTMGGSICGNGSSQNSCSYSNLTSSSLTQSSCAVTQQMSNISGSCSMLQQTSI 1740
            ENPSSYDSTMGGSICGNGSSQNSCSYSNLTSSSLTQSSCAVTQQMSNISGSCSMLQQTSI
Sbjct: 1681 ENPSSYDSTMGGSICGNGSSQNSCSYSNLTSSSLTQSSCAVTQQMSNISGSCSMLQQTSI 1740

Query: 1741 SSPPTCSVKSPQGCVVERPPSSSQQLAQCSMAANFTPPMQLAEIPETSNANIGLYERMGQ 1800
            SSPPTCSVKSPQGCVVERPPSSSQQLAQCSMAANFTPPMQLAEIPETSNANIGLYERMGQ
Sbjct: 1741 SSPPTCSVKSPQGCVVERPPSSSQQLAQCSMAANFTPPMQLAEIPETSNANIGLYERMGQ 1800

Query: 1801 SDFGAGHYPQPSATFSLAKLQQLTNTLIDHSLPYSHSAAVTSYANSASLSTPLSNTGLVQ 1860
            SDFGAGHYPQPSATFSLAKLQQLTNTLIDHSLPYSHSAAVTSYANSASLSTPLSNTGLVQ
Sbjct: 1801 SDFGAGHYPQPSATFSLAKLQQLTNTLIDHSLPYSHSAAVTSYANSASLSTPLSNTGLVQ 1860

Query: 1861 LSQSPHSVPGGPQAQATMTPPPNLTPPPMNLPPPLLQRNMAASNIGISHSQRLQTQIASK 1920
            LSQSPHSVPGGPQAQATMTPPPNLTPPPMNLPPPLLQRNMAASNIGISHSQRLQTQIASK
Sbjct: 1861 LSQSPHSVPGGPQAQATMTPPPNLTPPPMNLPPPLLQRNMAASNIGISHSQRLQTQIASK 1920

Query: 1921 GHISMRTKSASLSPAAATHQSQIYGRSQTVAMQGPARTLTMQRGMNMSVNLMPAPAYNVN 1980
            GHISMRTKSASLSPAAATHQSQIYGRSQTVAMQGPARTLTMQRGMNMSVNLMPAPAYNVN
Sbjct: 1921 GHISMRTKSASLSPAAATHQSQIYGRSQTVAMQGPARTLTMQRGMNMSVNLMPAPAYNVN 1980

Query: 1981 SVNMNMNTLNAMNGYSMSQPMMNSGYHSNHGYMNQTPQYPMQMQMGMMGTQPYAQQPMQT 2040
            SVNMNMNTLNAMNGYSMSQPMMNSGYHSNHGYMNQTPQYPMQMQMGMMGTQPYAQQPMQT
Sbjct: 1981 SVNMNMNTLNAMNGYSMSQPMMNSGYHSNHGYMNQTPQYPMQMQMGMMGTQPYAQQPMQT 2040

Query: 2041 PPHGNMMYTAPGHHGYMNTGMSKQSLNGSYMRR 2073
            PPHGNMMYTAPGHHGYMNTGMSKQSLNGSYMRR
Sbjct: 2041 PPHGNMMYTAPGHHGYMNTGMSKQSLNGSYMRR 2073


>gi|150378543 MYST histone acetyltransferase (monocytic leukemia) 3
            [Homo sapiens]
          Length = 2004

 Score = 1384 bits (3583), Expect = 0.0
 Identities = 808/1595 (50%), Positives = 989/1595 (62%), Gaps = 247/1595 (15%)

Query: 673  KQESADVNVIGNKDVVTEEDLDVFKQAQELSWEKIECESGVEDCGRYPSVIEFGKYEIQT 732
            KQE+ +  + G+++++TE+D+++F+  QE + +K+      +   R PSVIEFGKYEI T
Sbjct: 463  KQENEE-RLFGSQEIMTEKDMELFRDIQEQALQKVGVTGPPDPQVRCPSVIEFGKYEIHT 521

Query: 733  WYSSPYPQEYARLPKLYLCEFCLKYMKSKNILLRHSKKCGWFHPPANEIYRRKDLSVFEV 792
            WYSSPYPQEY+RLPKLYLCEFCLKYMKS+ IL +H KKCGWFHPPANEIYR+ ++SVFEV
Sbjct: 522  WYSSPYPQEYSRLPKLYLCEFCLKYMKSRTILQQHMKKCGWFHPPANEIYRKNNISVFEV 581

Query: 793  DGNMSKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVLTKNDEKGCHLVGYFSKEKLCQQK 852
            DGN+S IYCQNLCLLAKLFLDHKTLYYDVEPFLFYVLT+ND KGCHLVGYFSKEK CQQK
Sbjct: 582  DGNVSTIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVLTQNDVKGCHLVGYFSKEKHCQQK 641

Query: 853  YNVSCIMIMPQHQRQGFGRFLIDFSYLLSRREGQAGSPEKPLSDLGRLSYLAYWKSVILE 912
            YNVSCIMI+PQ+QR+G+GRFLIDFSYLLS+REGQAGSPEKPLSDLGRLSY+AYWKSVILE
Sbjct: 642  YNVSCIMILPQYQRKGYGRFLIDFSYLLSKREGQAGSPEKPLSDLGRLSYMAYWKSVILE 701

Query: 913  YLYHHHERHISIKAISRATGMCPHDIATTLQHLHMIDKRDGRFVIIRREKLILSHMEKLK 972
             LYH +++ ISIK +S+ TG+CP DI +TL HL M+D R  +FVIIRREKLI  HM KL+
Sbjct: 702  CLYHQNDKQISIKKLSKLTGICPQDITSTLHHLRMLDFRSDQFVIIRREKLIQDHMAKLQ 761

Query: 973  TCSRANELDPDSLRWTPILISNAAVSE-EEREA-----------EKEAERLMEQASCWEK 1020
               R  ++DP+ LRWTP+++SN+ VSE EE EA           E+E E  + ++   E 
Sbjct: 762  LNLRPVDVDPECLRWTPVIVSNSVVSEEEEEEAEEGENEEPQCQERELEISVGKSVSHEN 821

Query: 1021 EEQ-----------EILSTRANSRQS---------PAKVQSKNK---------------- 1044
            +EQ           E+++  +++R S         PA  Q   +                
Sbjct: 822  KEQDSYSVESEKKPEVMAPVSSTRLSKQVLPHDSLPANSQPSRRGRWGRKNRKTQERFGD 881

Query: 1045 -----YLHSPESRPVT--GERGQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEE---- 1093
                  L    S P    GE G+  E ++E   E EE+    EE+  ++ + D  +    
Sbjct: 882  KDSKLLLEETSSAPQEQYGECGEKSEATQEQYTESEEQLVASEEQPSQDGKPDLPKRRLS 941

Query: 1094 --------------------------------------------EEEEEEEEEEENIQSS 1109
                                                        E  EEEEE E    SS
Sbjct: 942  EGVEPWRGQLKKSPEALKCRLTEGSERLPRRYSEGDRAVLRGFSESSEEEEEPESPRSSS 1001

Query: 1110 PPRLTKPQSVAIKRKRPFVLKKKRGRKRRRINSSVTTETISETTEVLNEPFDNSDEERPM 1169
            PP LTKP    +KRK+PF+ +++R RKR+  NSSV TETISETTEVL+EPF++SD ERPM
Sbjct: 1002 PPILTKP---TLKRKKPFLHRRRRVRKRKHHNSSVVTETISETTEVLDEPFEDSDSERPM 1058

Query: 1170 PQLEPTCEIEVEED----------------GRKPVLRKAFQHQPGKKRQTEEEEGKDNHC 1213
            P+LEPT EI+ EE+                  + VLR     +   K + E+EE  D   
Sbjct: 1059 PRLEPTFEIDEEEEEEDENELFPREYFRRLSSQDVLRCQSSSKRKSKDEEEDEESDDADD 1118

Query: 1214 FKNADPCRNNMNDDSSNLKEGSKDNPEPLKCKQVWPKGTKRGLSKWRQNKERKTGFKLNL 1273
                 P       D  N      D   PLK K+ WPKG  R    W++   RK GFKL+ 
Sbjct: 1119 TPILKPVSLLRKRDVKN-SPLEPDTSTPLKKKKGWPKGKSRKPIHWKKRPGRKPGFKLSR 1177

Query: 1274 YTPPETP----MEPDEQVT-------VEEQKETSEGKTS---PSPIRIEEEVKETGEALL 1319
               P +     +EP   +        ++E +ET E K     P   + EEE++   E   
Sbjct: 1178 EIMPVSTQACVIEPIVSIPKAGRKPKIQESEETVEPKEDMPLPEERKEEEEMQAEAEEAE 1237

Query: 1320 PQEENRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGEEEEGGGNVE 1379
              EE     +  P +        PE +  +PE EEEEE+    EE+ +  EE+       
Sbjct: 1238 EGEEEDAASSEVPAASPADSSNSPETETKEPEVEEEEEKPRVSEEQRQSEEEQ------- 1290

Query: 1380 KDPDGAKSQEKEEPEISTEKEDSARLDDHEEEEEEDEEPSHNEDHDADDEDDSHMESAEV 1439
                    QE EEPE              EEEE+   E + N+DHDADDEDD H+ES + 
Sbjct: 1291 --------QELEEPE-------------PEEEEDAAAETAQNDDHDADDEDDGHLESTKK 1329

Query: 1440 -EKEELP-RESFKEVLENQETFLDLNVQPGHSNPEVLMDCGVDLTASCNSEPKELAGDPE 1497
             E EE P RE  KE    QE+FLD N+Q      +   +  +D      SE ++ + D  
Sbjct: 1330 KELEEQPTREDVKEEPGVQESFLDANMQKSREKIKDKEETELD------SEEEQPSHDTS 1383

Query: 1498 AVPESDEEPPPGEQAQKQDQKNSKEVDTEFKEGNPAT-MEIDSETVQAVQSLTQE-SSEQ 1555
             V E       G +   ++  ++KE   E KE       E+D ETVQAVQSLTQE SSE 
Sbjct: 1384 VVSEQ----MAGSEDDHEEDSHTKEELIELKEEEEIPHSELDLETVQAVQSLTQEESSEH 1439

Query: 1556 DDTFQDCAETQEACRSLQNYTRADQSPQIATTLDDCQQSDHSSPVSSVHSHPGQSVRSVN 1615
            +  +QDC ET  AC++LQ+YT+AD+ PQ++  ++DC  S+H+SP+SSV SHP QSVRSV+
Sbjct: 1440 EGAYQDCEETLAACQTLQSYTQADEDPQMSM-VEDCHASEHNSPISSVQSHPSQSVRSVS 1498

Query: 1616 SPSVPALENSYAQISPDQSAISVPSLQNMETSPMMDVPSVSDHSQQVVDSGFSDLGSIES 1675
            SP+VPALE+ Y QISP+Q ++S PS+QNMETSPMMDVPSVSDHSQQVVDSGFSDLGSIES
Sbjct: 1499 SPNVPALESGYTQISPEQGSLSAPSMQNMETSPMMDVPSVSDHSQQVVDSGFSDLGSIES 1558

Query: 1676 TTENYENPSSYDSTMGGSICGNGSSQNSCSYSNLTSSS-LTQSSCAVTQQMSNISGSCSM 1734
            TTENYENPSSYDSTMGGSICGN SSQ+SCSY  L+SSS LTQSSC VTQQM+++  SCSM
Sbjct: 1559 TTENYENPSSYDSTMGGSICGNSSSQSSCSYGGLSSSSSLTQSSCVVTQQMASMGSSCSM 1618

Query: 1735 LQQTSISSPPTCSVKSPQGCVVERPPSSSQQ----------------------------- 1765
            +QQ+S+     CS+KSPQ CVVERPPS+ QQ                             
Sbjct: 1619 MQQSSVQPAANCSIKSPQSCVVERPPSNQQQQPPPPPPQQPQPPPPQPQPAPQPPPPQQQ 1678

Query: 1766 -----------------------LAQCSMAANFTPPMQLAEIPET-SNANIGLYERMGQS 1801
                                   L+QCSM  +FTP   + EIPE+ S  NI +YER+   
Sbjct: 1679 PQQQPQPQPQQPPPPPPPQQQPPLSQCSMNNSFTPAPMIMEIPESGSTGNISIYERI-PG 1737

Query: 1802 DFGAGHYPQPSATFSLAKLQQLTNTLID-HSLPYSHSAAVTSYANSASLSTPLSNTGLVQ 1860
            DFGAG Y QPSATFSLAKLQQLTNT++D H++PYSHS AVTSYA S SLS    NTGL Q
Sbjct: 1738 DFGAGSYSQPSATFSLAKLQQLTNTIMDPHAMPYSHSPAVTSYATSVSLS----NTGLAQ 1793

Query: 1861 LSQSPHSVPGGPQAQATMTPPPNLTPPPMNLPPPLLQRNMAASNIGISHSQRLQTQIASK 1920
            L+ S H + G PQAQATMTPPPNL    MNL  PLLQ NM+A+NIGI H+QRLQ Q+  K
Sbjct: 1794 LAPS-HPLAGTPQAQATMTPPPNLASTTMNLTSPLLQCNMSATNIGIPHTQRLQGQMPVK 1852

Query: 1921 GHISMRTKSASLSPAAATHQSQIYGRS-QTVAMQGPARTLTMQRGMNMSVNLMPAPAYNV 1979
            GHIS+R+KSA L P+AA HQ Q+YGRS   VAMQ   R L +QRGMNM VNLMP PAYNV
Sbjct: 1853 GHISIRSKSAPL-PSAAAHQQQLYGRSPSAVAMQAGPRALAVQRGMNMGVNLMPTPAYNV 1911

Query: 1980 NSVNMNMNTLNAMNGYSMSQPMMNSGYHSNHGYMNQTPQYPMQMQMGMMGTQPYAQQPMQ 2039
            NS  MNMNTLNAMN Y M+QPMMNS YHSN  YMNQT QYPMQMQMGMMG+Q Y QQPMQ
Sbjct: 1912 NS--MNMNTLNAMNSYRMTQPMMNSSYHSNPAYMNQTAQYPMQMQMGMMGSQAYTQQPMQ 1969

Query: 2040 TPPHGNMMYTAPGHHGYMN-TGMSKQSLNGSYMRR 2073
              PHGNMMYT P HH YMN  G+ KQSLNG YMRR
Sbjct: 1970 PNPHGNMMYTGPSHHSYMNAAGVPKQSLNGPYMRR 2004



 Score =  602 bits (1553), Expect = e-172
 Identities = 302/476 (63%), Positives = 365/476 (76%), Gaps = 31/476 (6%)

Query: 1   MVKLANPLYTEWILEAIQKIKKQKQRPSEERICHAVSTSHGLDKKTVSEQLELSVQDGSV 60
           MVKLANPLYTEWILEAI+K+KKQKQRPSEERIC+AVS+SHGLD+KTV EQLELSV+DG++
Sbjct: 1   MVKLANPLYTEWILEAIKKVKKQKQRPSEERICNAVSSSHGLDRKTVLEQLELSVKDGTI 60

Query: 61  LKVTNKGLASYKDPDNPGRFSSVKPGTFPKSAKGSRGSCNDLRNVDWNKLLRRAIEGLEE 120
           LKV+NKGL SYKDPDNPGR +  KP         + G  ++ +NVDWNKL++RA+EGL E
Sbjct: 61  LKVSNKGLNSYKDPDNPGRIALPKPR--------NHGKLDNKQNVDWNKLIKRAVEGLAE 112

Query: 121 PNGSSLKNIEKYLRSQSDLTSTTNNPA---FQQRLRLGAKRAVNNGRLLKDGPQYRVNYG 177
             GS+LK+IE++L+ Q D+++     A   F Q+LRL  KRA+ +GRLLKDGP YR+N  
Sbjct: 113 SGGSTLKSIERFLKGQKDVSALFGGSAASGFHQQLRLAIKRAIGHGRLLKDGPLYRLNTK 172

Query: 178 SLDGKGAPQYPSAFPSSLPPVSLLPHEKDQPRADPIPICSFCLGTKESNREKKPEELLSC 237
           + +  G     S   S LPPVSLLPHEKD+P A+PIPICSFCLGTKE NREKKPEEL+SC
Sbjct: 173 ATNVDGKESCESL--SCLPPVSLLPHEKDKPVAEPIPICSFCLGTKEQNREKKPEELISC 230

Query: 238 ADCGSSGHPSCLKFCPELTTNVKALRWQCIECKTCSACRVQGRNADNMLFCDSCDRGFHM 297
           ADCG+SGHPSCLKF PELT  VKALRWQCIECKTCS+CR QG+NADNMLFCDSCDRGFHM
Sbjct: 231 ADCGNSGHPSCLKFSPELTVRVKALRWQCIECKTCSSCRDQGKNADNMLFCDSCDRGFHM 290

Query: 298 ECCDPPLSRMPKGMWICQVCRPKKKGRKLLHEKAAQIKRRYAKPIGRPKNKLKQRLLSVT 357
           ECCDPPL+RMPKGMWICQ+CRP+KKGRKLL +KAAQIKRRY  PIGRPKN+LK++    T
Sbjct: 291 ECCDPPLTRMPKGMWICQICRPRKKGRKLLQKKAAQIKRRYTNPIGRPKNRLKKQ---NT 347

Query: 358 SDEGSMNAFTGRGSPGRGQKTKVCTTPSSGHAASGKDSSSRLAVTDPTRPGATTKITTTS 417
             +G  +    R  PGRG+K K+  +  S  ++S +    R+   D  R           
Sbjct: 348 VSKGPFSKV--RTGPGRGRKRKITLSSQSASSSSEEGYLERIDGLDFCRD---------- 395

Query: 418 TYISASTLKVNKKTKGLIDGLTKFFTPSPDGRRSRGEIIDFSKHYRPRKKVSQKQS 473
              S  +LK NKKTKGLIDGLTKFFTPSPDGR++RGE++D+S+ YR RK+ ++K S
Sbjct: 396 ---SNVSLKFNKKTKGLIDGLTKFFTPSPDGRKARGEVVDYSEQYRIRKRGNRKSS 448


>gi|150378463 MYST histone acetyltransferase (monocytic leukemia) 3
            [Homo sapiens]
          Length = 2004

 Score = 1384 bits (3583), Expect = 0.0
 Identities = 808/1595 (50%), Positives = 989/1595 (62%), Gaps = 247/1595 (15%)

Query: 673  KQESADVNVIGNKDVVTEEDLDVFKQAQELSWEKIECESGVEDCGRYPSVIEFGKYEIQT 732
            KQE+ +  + G+++++TE+D+++F+  QE + +K+      +   R PSVIEFGKYEI T
Sbjct: 463  KQENEE-RLFGSQEIMTEKDMELFRDIQEQALQKVGVTGPPDPQVRCPSVIEFGKYEIHT 521

Query: 733  WYSSPYPQEYARLPKLYLCEFCLKYMKSKNILLRHSKKCGWFHPPANEIYRRKDLSVFEV 792
            WYSSPYPQEY+RLPKLYLCEFCLKYMKS+ IL +H KKCGWFHPPANEIYR+ ++SVFEV
Sbjct: 522  WYSSPYPQEYSRLPKLYLCEFCLKYMKSRTILQQHMKKCGWFHPPANEIYRKNNISVFEV 581

Query: 793  DGNMSKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVLTKNDEKGCHLVGYFSKEKLCQQK 852
            DGN+S IYCQNLCLLAKLFLDHKTLYYDVEPFLFYVLT+ND KGCHLVGYFSKEK CQQK
Sbjct: 582  DGNVSTIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVLTQNDVKGCHLVGYFSKEKHCQQK 641

Query: 853  YNVSCIMIMPQHQRQGFGRFLIDFSYLLSRREGQAGSPEKPLSDLGRLSYLAYWKSVILE 912
            YNVSCIMI+PQ+QR+G+GRFLIDFSYLLS+REGQAGSPEKPLSDLGRLSY+AYWKSVILE
Sbjct: 642  YNVSCIMILPQYQRKGYGRFLIDFSYLLSKREGQAGSPEKPLSDLGRLSYMAYWKSVILE 701

Query: 913  YLYHHHERHISIKAISRATGMCPHDIATTLQHLHMIDKRDGRFVIIRREKLILSHMEKLK 972
             LYH +++ ISIK +S+ TG+CP DI +TL HL M+D R  +FVIIRREKLI  HM KL+
Sbjct: 702  CLYHQNDKQISIKKLSKLTGICPQDITSTLHHLRMLDFRSDQFVIIRREKLIQDHMAKLQ 761

Query: 973  TCSRANELDPDSLRWTPILISNAAVSE-EEREA-----------EKEAERLMEQASCWEK 1020
               R  ++DP+ LRWTP+++SN+ VSE EE EA           E+E E  + ++   E 
Sbjct: 762  LNLRPVDVDPECLRWTPVIVSNSVVSEEEEEEAEEGENEEPQCQERELEISVGKSVSHEN 821

Query: 1021 EEQ-----------EILSTRANSRQS---------PAKVQSKNK---------------- 1044
            +EQ           E+++  +++R S         PA  Q   +                
Sbjct: 822  KEQDSYSVESEKKPEVMAPVSSTRLSKQVLPHDSLPANSQPSRRGRWGRKNRKTQERFGD 881

Query: 1045 -----YLHSPESRPVT--GERGQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEE---- 1093
                  L    S P    GE G+  E ++E   E EE+    EE+  ++ + D  +    
Sbjct: 882  KDSKLLLEETSSAPQEQYGECGEKSEATQEQYTESEEQLVASEEQPSQDGKPDLPKRRLS 941

Query: 1094 --------------------------------------------EEEEEEEEEEENIQSS 1109
                                                        E  EEEEE E    SS
Sbjct: 942  EGVEPWRGQLKKSPEALKCRLTEGSERLPRRYSEGDRAVLRGFSESSEEEEEPESPRSSS 1001

Query: 1110 PPRLTKPQSVAIKRKRPFVLKKKRGRKRRRINSSVTTETISETTEVLNEPFDNSDEERPM 1169
            PP LTKP    +KRK+PF+ +++R RKR+  NSSV TETISETTEVL+EPF++SD ERPM
Sbjct: 1002 PPILTKP---TLKRKKPFLHRRRRVRKRKHHNSSVVTETISETTEVLDEPFEDSDSERPM 1058

Query: 1170 PQLEPTCEIEVEED----------------GRKPVLRKAFQHQPGKKRQTEEEEGKDNHC 1213
            P+LEPT EI+ EE+                  + VLR     +   K + E+EE  D   
Sbjct: 1059 PRLEPTFEIDEEEEEEDENELFPREYFRRLSSQDVLRCQSSSKRKSKDEEEDEESDDADD 1118

Query: 1214 FKNADPCRNNMNDDSSNLKEGSKDNPEPLKCKQVWPKGTKRGLSKWRQNKERKTGFKLNL 1273
                 P       D  N      D   PLK K+ WPKG  R    W++   RK GFKL+ 
Sbjct: 1119 TPILKPVSLLRKRDVKN-SPLEPDTSTPLKKKKGWPKGKSRKPIHWKKRPGRKPGFKLSR 1177

Query: 1274 YTPPETP----MEPDEQVT-------VEEQKETSEGKTS---PSPIRIEEEVKETGEALL 1319
               P +     +EP   +        ++E +ET E K     P   + EEE++   E   
Sbjct: 1178 EIMPVSTQACVIEPIVSIPKAGRKPKIQESEETVEPKEDMPLPEERKEEEEMQAEAEEAE 1237

Query: 1320 PQEENRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGEEEEGGGNVE 1379
              EE     +  P +        PE +  +PE EEEEE+    EE+ +  EE+       
Sbjct: 1238 EGEEEDAASSEVPAASPADSSNSPETETKEPEVEEEEEKPRVSEEQRQSEEEQ------- 1290

Query: 1380 KDPDGAKSQEKEEPEISTEKEDSARLDDHEEEEEEDEEPSHNEDHDADDEDDSHMESAEV 1439
                    QE EEPE              EEEE+   E + N+DHDADDEDD H+ES + 
Sbjct: 1291 --------QELEEPE-------------PEEEEDAAAETAQNDDHDADDEDDGHLESTKK 1329

Query: 1440 -EKEELP-RESFKEVLENQETFLDLNVQPGHSNPEVLMDCGVDLTASCNSEPKELAGDPE 1497
             E EE P RE  KE    QE+FLD N+Q      +   +  +D      SE ++ + D  
Sbjct: 1330 KELEEQPTREDVKEEPGVQESFLDANMQKSREKIKDKEETELD------SEEEQPSHDTS 1383

Query: 1498 AVPESDEEPPPGEQAQKQDQKNSKEVDTEFKEGNPAT-MEIDSETVQAVQSLTQE-SSEQ 1555
             V E       G +   ++  ++KE   E KE       E+D ETVQAVQSLTQE SSE 
Sbjct: 1384 VVSEQ----MAGSEDDHEEDSHTKEELIELKEEEEIPHSELDLETVQAVQSLTQEESSEH 1439

Query: 1556 DDTFQDCAETQEACRSLQNYTRADQSPQIATTLDDCQQSDHSSPVSSVHSHPGQSVRSVN 1615
            +  +QDC ET  AC++LQ+YT+AD+ PQ++  ++DC  S+H+SP+SSV SHP QSVRSV+
Sbjct: 1440 EGAYQDCEETLAACQTLQSYTQADEDPQMSM-VEDCHASEHNSPISSVQSHPSQSVRSVS 1498

Query: 1616 SPSVPALENSYAQISPDQSAISVPSLQNMETSPMMDVPSVSDHSQQVVDSGFSDLGSIES 1675
            SP+VPALE+ Y QISP+Q ++S PS+QNMETSPMMDVPSVSDHSQQVVDSGFSDLGSIES
Sbjct: 1499 SPNVPALESGYTQISPEQGSLSAPSMQNMETSPMMDVPSVSDHSQQVVDSGFSDLGSIES 1558

Query: 1676 TTENYENPSSYDSTMGGSICGNGSSQNSCSYSNLTSSS-LTQSSCAVTQQMSNISGSCSM 1734
            TTENYENPSSYDSTMGGSICGN SSQ+SCSY  L+SSS LTQSSC VTQQM+++  SCSM
Sbjct: 1559 TTENYENPSSYDSTMGGSICGNSSSQSSCSYGGLSSSSSLTQSSCVVTQQMASMGSSCSM 1618

Query: 1735 LQQTSISSPPTCSVKSPQGCVVERPPSSSQQ----------------------------- 1765
            +QQ+S+     CS+KSPQ CVVERPPS+ QQ                             
Sbjct: 1619 MQQSSVQPAANCSIKSPQSCVVERPPSNQQQQPPPPPPQQPQPPPPQPQPAPQPPPPQQQ 1678

Query: 1766 -----------------------LAQCSMAANFTPPMQLAEIPET-SNANIGLYERMGQS 1801
                                   L+QCSM  +FTP   + EIPE+ S  NI +YER+   
Sbjct: 1679 PQQQPQPQPQQPPPPPPPQQQPPLSQCSMNNSFTPAPMIMEIPESGSTGNISIYERI-PG 1737

Query: 1802 DFGAGHYPQPSATFSLAKLQQLTNTLID-HSLPYSHSAAVTSYANSASLSTPLSNTGLVQ 1860
            DFGAG Y QPSATFSLAKLQQLTNT++D H++PYSHS AVTSYA S SLS    NTGL Q
Sbjct: 1738 DFGAGSYSQPSATFSLAKLQQLTNTIMDPHAMPYSHSPAVTSYATSVSLS----NTGLAQ 1793

Query: 1861 LSQSPHSVPGGPQAQATMTPPPNLTPPPMNLPPPLLQRNMAASNIGISHSQRLQTQIASK 1920
            L+ S H + G PQAQATMTPPPNL    MNL  PLLQ NM+A+NIGI H+QRLQ Q+  K
Sbjct: 1794 LAPS-HPLAGTPQAQATMTPPPNLASTTMNLTSPLLQCNMSATNIGIPHTQRLQGQMPVK 1852

Query: 1921 GHISMRTKSASLSPAAATHQSQIYGRS-QTVAMQGPARTLTMQRGMNMSVNLMPAPAYNV 1979
            GHIS+R+KSA L P+AA HQ Q+YGRS   VAMQ   R L +QRGMNM VNLMP PAYNV
Sbjct: 1853 GHISIRSKSAPL-PSAAAHQQQLYGRSPSAVAMQAGPRALAVQRGMNMGVNLMPTPAYNV 1911

Query: 1980 NSVNMNMNTLNAMNGYSMSQPMMNSGYHSNHGYMNQTPQYPMQMQMGMMGTQPYAQQPMQ 2039
            NS  MNMNTLNAMN Y M+QPMMNS YHSN  YMNQT QYPMQMQMGMMG+Q Y QQPMQ
Sbjct: 1912 NS--MNMNTLNAMNSYRMTQPMMNSSYHSNPAYMNQTAQYPMQMQMGMMGSQAYTQQPMQ 1969

Query: 2040 TPPHGNMMYTAPGHHGYMN-TGMSKQSLNGSYMRR 2073
              PHGNMMYT P HH YMN  G+ KQSLNG YMRR
Sbjct: 1970 PNPHGNMMYTGPSHHSYMNAAGVPKQSLNGPYMRR 2004



 Score =  602 bits (1553), Expect = e-172
 Identities = 302/476 (63%), Positives = 365/476 (76%), Gaps = 31/476 (6%)

Query: 1   MVKLANPLYTEWILEAIQKIKKQKQRPSEERICHAVSTSHGLDKKTVSEQLELSVQDGSV 60
           MVKLANPLYTEWILEAI+K+KKQKQRPSEERIC+AVS+SHGLD+KTV EQLELSV+DG++
Sbjct: 1   MVKLANPLYTEWILEAIKKVKKQKQRPSEERICNAVSSSHGLDRKTVLEQLELSVKDGTI 60

Query: 61  LKVTNKGLASYKDPDNPGRFSSVKPGTFPKSAKGSRGSCNDLRNVDWNKLLRRAIEGLEE 120
           LKV+NKGL SYKDPDNPGR +  KP         + G  ++ +NVDWNKL++RA+EGL E
Sbjct: 61  LKVSNKGLNSYKDPDNPGRIALPKPR--------NHGKLDNKQNVDWNKLIKRAVEGLAE 112

Query: 121 PNGSSLKNIEKYLRSQSDLTSTTNNPA---FQQRLRLGAKRAVNNGRLLKDGPQYRVNYG 177
             GS+LK+IE++L+ Q D+++     A   F Q+LRL  KRA+ +GRLLKDGP YR+N  
Sbjct: 113 SGGSTLKSIERFLKGQKDVSALFGGSAASGFHQQLRLAIKRAIGHGRLLKDGPLYRLNTK 172

Query: 178 SLDGKGAPQYPSAFPSSLPPVSLLPHEKDQPRADPIPICSFCLGTKESNREKKPEELLSC 237
           + +  G     S   S LPPVSLLPHEKD+P A+PIPICSFCLGTKE NREKKPEEL+SC
Sbjct: 173 ATNVDGKESCESL--SCLPPVSLLPHEKDKPVAEPIPICSFCLGTKEQNREKKPEELISC 230

Query: 238 ADCGSSGHPSCLKFCPELTTNVKALRWQCIECKTCSACRVQGRNADNMLFCDSCDRGFHM 297
           ADCG+SGHPSCLKF PELT  VKALRWQCIECKTCS+CR QG+NADNMLFCDSCDRGFHM
Sbjct: 231 ADCGNSGHPSCLKFSPELTVRVKALRWQCIECKTCSSCRDQGKNADNMLFCDSCDRGFHM 290

Query: 298 ECCDPPLSRMPKGMWICQVCRPKKKGRKLLHEKAAQIKRRYAKPIGRPKNKLKQRLLSVT 357
           ECCDPPL+RMPKGMWICQ+CRP+KKGRKLL +KAAQIKRRY  PIGRPKN+LK++    T
Sbjct: 291 ECCDPPLTRMPKGMWICQICRPRKKGRKLLQKKAAQIKRRYTNPIGRPKNRLKKQ---NT 347

Query: 358 SDEGSMNAFTGRGSPGRGQKTKVCTTPSSGHAASGKDSSSRLAVTDPTRPGATTKITTTS 417
             +G  +    R  PGRG+K K+  +  S  ++S +    R+   D  R           
Sbjct: 348 VSKGPFSKV--RTGPGRGRKRKITLSSQSASSSSEEGYLERIDGLDFCRD---------- 395

Query: 418 TYISASTLKVNKKTKGLIDGLTKFFTPSPDGRRSRGEIIDFSKHYRPRKKVSQKQS 473
              S  +LK NKKTKGLIDGLTKFFTPSPDGR++RGE++D+S+ YR RK+ ++K S
Sbjct: 396 ---SNVSLKFNKKTKGLIDGLTKFFTPSPDGRKARGEVVDYSEQYRIRKRGNRKSS 448


>gi|150378493 MYST histone acetyltransferase (monocytic leukemia) 3
            [Homo sapiens]
          Length = 2004

 Score = 1384 bits (3583), Expect = 0.0
 Identities = 808/1595 (50%), Positives = 989/1595 (62%), Gaps = 247/1595 (15%)

Query: 673  KQESADVNVIGNKDVVTEEDLDVFKQAQELSWEKIECESGVEDCGRYPSVIEFGKYEIQT 732
            KQE+ +  + G+++++TE+D+++F+  QE + +K+      +   R PSVIEFGKYEI T
Sbjct: 463  KQENEE-RLFGSQEIMTEKDMELFRDIQEQALQKVGVTGPPDPQVRCPSVIEFGKYEIHT 521

Query: 733  WYSSPYPQEYARLPKLYLCEFCLKYMKSKNILLRHSKKCGWFHPPANEIYRRKDLSVFEV 792
            WYSSPYPQEY+RLPKLYLCEFCLKYMKS+ IL +H KKCGWFHPPANEIYR+ ++SVFEV
Sbjct: 522  WYSSPYPQEYSRLPKLYLCEFCLKYMKSRTILQQHMKKCGWFHPPANEIYRKNNISVFEV 581

Query: 793  DGNMSKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVLTKNDEKGCHLVGYFSKEKLCQQK 852
            DGN+S IYCQNLCLLAKLFLDHKTLYYDVEPFLFYVLT+ND KGCHLVGYFSKEK CQQK
Sbjct: 582  DGNVSTIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVLTQNDVKGCHLVGYFSKEKHCQQK 641

Query: 853  YNVSCIMIMPQHQRQGFGRFLIDFSYLLSRREGQAGSPEKPLSDLGRLSYLAYWKSVILE 912
            YNVSCIMI+PQ+QR+G+GRFLIDFSYLLS+REGQAGSPEKPLSDLGRLSY+AYWKSVILE
Sbjct: 642  YNVSCIMILPQYQRKGYGRFLIDFSYLLSKREGQAGSPEKPLSDLGRLSYMAYWKSVILE 701

Query: 913  YLYHHHERHISIKAISRATGMCPHDIATTLQHLHMIDKRDGRFVIIRREKLILSHMEKLK 972
             LYH +++ ISIK +S+ TG+CP DI +TL HL M+D R  +FVIIRREKLI  HM KL+
Sbjct: 702  CLYHQNDKQISIKKLSKLTGICPQDITSTLHHLRMLDFRSDQFVIIRREKLIQDHMAKLQ 761

Query: 973  TCSRANELDPDSLRWTPILISNAAVSE-EEREA-----------EKEAERLMEQASCWEK 1020
               R  ++DP+ LRWTP+++SN+ VSE EE EA           E+E E  + ++   E 
Sbjct: 762  LNLRPVDVDPECLRWTPVIVSNSVVSEEEEEEAEEGENEEPQCQERELEISVGKSVSHEN 821

Query: 1021 EEQ-----------EILSTRANSRQS---------PAKVQSKNK---------------- 1044
            +EQ           E+++  +++R S         PA  Q   +                
Sbjct: 822  KEQDSYSVESEKKPEVMAPVSSTRLSKQVLPHDSLPANSQPSRRGRWGRKNRKTQERFGD 881

Query: 1045 -----YLHSPESRPVT--GERGQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEE---- 1093
                  L    S P    GE G+  E ++E   E EE+    EE+  ++ + D  +    
Sbjct: 882  KDSKLLLEETSSAPQEQYGECGEKSEATQEQYTESEEQLVASEEQPSQDGKPDLPKRRLS 941

Query: 1094 --------------------------------------------EEEEEEEEEEENIQSS 1109
                                                        E  EEEEE E    SS
Sbjct: 942  EGVEPWRGQLKKSPEALKCRLTEGSERLPRRYSEGDRAVLRGFSESSEEEEEPESPRSSS 1001

Query: 1110 PPRLTKPQSVAIKRKRPFVLKKKRGRKRRRINSSVTTETISETTEVLNEPFDNSDEERPM 1169
            PP LTKP    +KRK+PF+ +++R RKR+  NSSV TETISETTEVL+EPF++SD ERPM
Sbjct: 1002 PPILTKP---TLKRKKPFLHRRRRVRKRKHHNSSVVTETISETTEVLDEPFEDSDSERPM 1058

Query: 1170 PQLEPTCEIEVEED----------------GRKPVLRKAFQHQPGKKRQTEEEEGKDNHC 1213
            P+LEPT EI+ EE+                  + VLR     +   K + E+EE  D   
Sbjct: 1059 PRLEPTFEIDEEEEEEDENELFPREYFRRLSSQDVLRCQSSSKRKSKDEEEDEESDDADD 1118

Query: 1214 FKNADPCRNNMNDDSSNLKEGSKDNPEPLKCKQVWPKGTKRGLSKWRQNKERKTGFKLNL 1273
                 P       D  N      D   PLK K+ WPKG  R    W++   RK GFKL+ 
Sbjct: 1119 TPILKPVSLLRKRDVKN-SPLEPDTSTPLKKKKGWPKGKSRKPIHWKKRPGRKPGFKLSR 1177

Query: 1274 YTPPETP----MEPDEQVT-------VEEQKETSEGKTS---PSPIRIEEEVKETGEALL 1319
               P +     +EP   +        ++E +ET E K     P   + EEE++   E   
Sbjct: 1178 EIMPVSTQACVIEPIVSIPKAGRKPKIQESEETVEPKEDMPLPEERKEEEEMQAEAEEAE 1237

Query: 1320 PQEENRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGEEEEGGGNVE 1379
              EE     +  P +        PE +  +PE EEEEE+    EE+ +  EE+       
Sbjct: 1238 EGEEEDAASSEVPAASPADSSNSPETETKEPEVEEEEEKPRVSEEQRQSEEEQ------- 1290

Query: 1380 KDPDGAKSQEKEEPEISTEKEDSARLDDHEEEEEEDEEPSHNEDHDADDEDDSHMESAEV 1439
                    QE EEPE              EEEE+   E + N+DHDADDEDD H+ES + 
Sbjct: 1291 --------QELEEPE-------------PEEEEDAAAETAQNDDHDADDEDDGHLESTKK 1329

Query: 1440 -EKEELP-RESFKEVLENQETFLDLNVQPGHSNPEVLMDCGVDLTASCNSEPKELAGDPE 1497
             E EE P RE  KE    QE+FLD N+Q      +   +  +D      SE ++ + D  
Sbjct: 1330 KELEEQPTREDVKEEPGVQESFLDANMQKSREKIKDKEETELD------SEEEQPSHDTS 1383

Query: 1498 AVPESDEEPPPGEQAQKQDQKNSKEVDTEFKEGNPAT-MEIDSETVQAVQSLTQE-SSEQ 1555
             V E       G +   ++  ++KE   E KE       E+D ETVQAVQSLTQE SSE 
Sbjct: 1384 VVSEQ----MAGSEDDHEEDSHTKEELIELKEEEEIPHSELDLETVQAVQSLTQEESSEH 1439

Query: 1556 DDTFQDCAETQEACRSLQNYTRADQSPQIATTLDDCQQSDHSSPVSSVHSHPGQSVRSVN 1615
            +  +QDC ET  AC++LQ+YT+AD+ PQ++  ++DC  S+H+SP+SSV SHP QSVRSV+
Sbjct: 1440 EGAYQDCEETLAACQTLQSYTQADEDPQMSM-VEDCHASEHNSPISSVQSHPSQSVRSVS 1498

Query: 1616 SPSVPALENSYAQISPDQSAISVPSLQNMETSPMMDVPSVSDHSQQVVDSGFSDLGSIES 1675
            SP+VPALE+ Y QISP+Q ++S PS+QNMETSPMMDVPSVSDHSQQVVDSGFSDLGSIES
Sbjct: 1499 SPNVPALESGYTQISPEQGSLSAPSMQNMETSPMMDVPSVSDHSQQVVDSGFSDLGSIES 1558

Query: 1676 TTENYENPSSYDSTMGGSICGNGSSQNSCSYSNLTSSS-LTQSSCAVTQQMSNISGSCSM 1734
            TTENYENPSSYDSTMGGSICGN SSQ+SCSY  L+SSS LTQSSC VTQQM+++  SCSM
Sbjct: 1559 TTENYENPSSYDSTMGGSICGNSSSQSSCSYGGLSSSSSLTQSSCVVTQQMASMGSSCSM 1618

Query: 1735 LQQTSISSPPTCSVKSPQGCVVERPPSSSQQ----------------------------- 1765
            +QQ+S+     CS+KSPQ CVVERPPS+ QQ                             
Sbjct: 1619 MQQSSVQPAANCSIKSPQSCVVERPPSNQQQQPPPPPPQQPQPPPPQPQPAPQPPPPQQQ 1678

Query: 1766 -----------------------LAQCSMAANFTPPMQLAEIPET-SNANIGLYERMGQS 1801
                                   L+QCSM  +FTP   + EIPE+ S  NI +YER+   
Sbjct: 1679 PQQQPQPQPQQPPPPPPPQQQPPLSQCSMNNSFTPAPMIMEIPESGSTGNISIYERI-PG 1737

Query: 1802 DFGAGHYPQPSATFSLAKLQQLTNTLID-HSLPYSHSAAVTSYANSASLSTPLSNTGLVQ 1860
            DFGAG Y QPSATFSLAKLQQLTNT++D H++PYSHS AVTSYA S SLS    NTGL Q
Sbjct: 1738 DFGAGSYSQPSATFSLAKLQQLTNTIMDPHAMPYSHSPAVTSYATSVSLS----NTGLAQ 1793

Query: 1861 LSQSPHSVPGGPQAQATMTPPPNLTPPPMNLPPPLLQRNMAASNIGISHSQRLQTQIASK 1920
            L+ S H + G PQAQATMTPPPNL    MNL  PLLQ NM+A+NIGI H+QRLQ Q+  K
Sbjct: 1794 LAPS-HPLAGTPQAQATMTPPPNLASTTMNLTSPLLQCNMSATNIGIPHTQRLQGQMPVK 1852

Query: 1921 GHISMRTKSASLSPAAATHQSQIYGRS-QTVAMQGPARTLTMQRGMNMSVNLMPAPAYNV 1979
            GHIS+R+KSA L P+AA HQ Q+YGRS   VAMQ   R L +QRGMNM VNLMP PAYNV
Sbjct: 1853 GHISIRSKSAPL-PSAAAHQQQLYGRSPSAVAMQAGPRALAVQRGMNMGVNLMPTPAYNV 1911

Query: 1980 NSVNMNMNTLNAMNGYSMSQPMMNSGYHSNHGYMNQTPQYPMQMQMGMMGTQPYAQQPMQ 2039
            NS  MNMNTLNAMN Y M+QPMMNS YHSN  YMNQT QYPMQMQMGMMG+Q Y QQPMQ
Sbjct: 1912 NS--MNMNTLNAMNSYRMTQPMMNSSYHSNPAYMNQTAQYPMQMQMGMMGSQAYTQQPMQ 1969

Query: 2040 TPPHGNMMYTAPGHHGYMN-TGMSKQSLNGSYMRR 2073
              PHGNMMYT P HH YMN  G+ KQSLNG YMRR
Sbjct: 1970 PNPHGNMMYTGPSHHSYMNAAGVPKQSLNGPYMRR 2004



 Score =  602 bits (1553), Expect = e-172
 Identities = 302/476 (63%), Positives = 365/476 (76%), Gaps = 31/476 (6%)

Query: 1   MVKLANPLYTEWILEAIQKIKKQKQRPSEERICHAVSTSHGLDKKTVSEQLELSVQDGSV 60
           MVKLANPLYTEWILEAI+K+KKQKQRPSEERIC+AVS+SHGLD+KTV EQLELSV+DG++
Sbjct: 1   MVKLANPLYTEWILEAIKKVKKQKQRPSEERICNAVSSSHGLDRKTVLEQLELSVKDGTI 60

Query: 61  LKVTNKGLASYKDPDNPGRFSSVKPGTFPKSAKGSRGSCNDLRNVDWNKLLRRAIEGLEE 120
           LKV+NKGL SYKDPDNPGR +  KP         + G  ++ +NVDWNKL++RA+EGL E
Sbjct: 61  LKVSNKGLNSYKDPDNPGRIALPKPR--------NHGKLDNKQNVDWNKLIKRAVEGLAE 112

Query: 121 PNGSSLKNIEKYLRSQSDLTSTTNNPA---FQQRLRLGAKRAVNNGRLLKDGPQYRVNYG 177
             GS+LK+IE++L+ Q D+++     A   F Q+LRL  KRA+ +GRLLKDGP YR+N  
Sbjct: 113 SGGSTLKSIERFLKGQKDVSALFGGSAASGFHQQLRLAIKRAIGHGRLLKDGPLYRLNTK 172

Query: 178 SLDGKGAPQYPSAFPSSLPPVSLLPHEKDQPRADPIPICSFCLGTKESNREKKPEELLSC 237
           + +  G     S   S LPPVSLLPHEKD+P A+PIPICSFCLGTKE NREKKPEEL+SC
Sbjct: 173 ATNVDGKESCESL--SCLPPVSLLPHEKDKPVAEPIPICSFCLGTKEQNREKKPEELISC 230

Query: 238 ADCGSSGHPSCLKFCPELTTNVKALRWQCIECKTCSACRVQGRNADNMLFCDSCDRGFHM 297
           ADCG+SGHPSCLKF PELT  VKALRWQCIECKTCS+CR QG+NADNMLFCDSCDRGFHM
Sbjct: 231 ADCGNSGHPSCLKFSPELTVRVKALRWQCIECKTCSSCRDQGKNADNMLFCDSCDRGFHM 290

Query: 298 ECCDPPLSRMPKGMWICQVCRPKKKGRKLLHEKAAQIKRRYAKPIGRPKNKLKQRLLSVT 357
           ECCDPPL+RMPKGMWICQ+CRP+KKGRKLL +KAAQIKRRY  PIGRPKN+LK++    T
Sbjct: 291 ECCDPPLTRMPKGMWICQICRPRKKGRKLLQKKAAQIKRRYTNPIGRPKNRLKKQ---NT 347

Query: 358 SDEGSMNAFTGRGSPGRGQKTKVCTTPSSGHAASGKDSSSRLAVTDPTRPGATTKITTTS 417
             +G  +    R  PGRG+K K+  +  S  ++S +    R+   D  R           
Sbjct: 348 VSKGPFSKV--RTGPGRGRKRKITLSSQSASSSSEEGYLERIDGLDFCRD---------- 395

Query: 418 TYISASTLKVNKKTKGLIDGLTKFFTPSPDGRRSRGEIIDFSKHYRPRKKVSQKQS 473
              S  +LK NKKTKGLIDGLTKFFTPSPDGR++RGE++D+S+ YR RK+ ++K S
Sbjct: 396 ---SNVSLKFNKKTKGLIDGLTKFFTPSPDGRKARGEVVDYSEQYRIRKRGNRKSS 448


>gi|5901962 MYST histone acetyltransferase 2 [Homo sapiens]
          Length = 611

 Score =  362 bits (929), Expect = 2e-99
 Identities = 237/622 (38%), Positives = 327/622 (52%), Gaps = 41/622 (6%)

Query: 385 SSGHAASGKDSSSRLAVTDPTRPGATTKITTTSTYISASTLKVNKKTKGLIDGLTKFFTP 444
           SS       D S+ L  TD +    T++ +   T  SA  L  + +    +  L  F T 
Sbjct: 10  SSSDGTEDSDFSTDLEHTDSSESDGTSRRSARVTRSSAR-LSQSSQDSSPVRNLQSFGTE 68

Query: 445 SPDGR-----RSRGEIIDFSKHYRPRKKVSQKQSCTSHVLATGTTQKLKPPPSSLPPPTP 499
            P        RS+ +    +    P ++     S T  V+     +          PP  
Sbjct: 69  EPAYSTRRVTRSQQQPTPVTPKKYPLRQTRSSGSETEQVVDFSDRETKNTADHDESPPRT 128

Query: 500 ISGQSPSSQKSSTATSSPSPQSSSSQCSVPSLSSLTTNSQLKALFDGLSHIYTTQGQSRK 559
            +G +PSS+ S    SSP+         V    S+  +  LK     LSH        R+
Sbjct: 129 PTGNAPSSE-SDIDISSPN---------VSHDESIAKDMSLKDSGSDLSH-----RPKRR 173

Query: 560 KGHPSYAPPKRMRRKTELSSTAKSKAHFFGKRDIRSRFISHSSSSSWGMARGSIFKAIAH 619
           + H SY     M+  T       S  H  GK +   R  S S    +        K  A 
Sbjct: 174 RFHESYN--FNMKCPTP---GCNSLGHLTGKHE---RHFSISGCPLYHNLSADECKVRAQ 225

Query: 620 FKRTTFLKK---HRMLGRLKYKVTPQMGTPSP--GKGSLTDGRIKPDQDDDTEIK---IN 671
            +     ++   HR     ++    Q  T      K  + + R K +     E K   + 
Sbjct: 226 SRDKQIEERMLSHRQDDNNRHATRHQAPTERQLRYKEKVAELRKKRNSGLSKEQKEKYME 285

Query: 672 IKQESADVNVIGNKDVVTEEDLDVFKQAQELS---WEKIECESGVEDCGRYPSVIEFGKY 728
            +Q   +      +++ +E DLD+F++AQ  +    EK+  +  + +       I FG+Y
Sbjct: 286 HRQTYGNTREPLLENLTSEYDLDLFRRAQARASEDLEKLRLQGQITEGSNMIKTIAFGRY 345

Query: 729 EIQTWYSSPYPQEYARLPKLYLCEFCLKYMKSKNILLRHSKKCGWFHPPANEIYRRKDLS 788
           E+ TWY SPYP+EYARL +LY+CEFCLKYMKS+ IL RH  KC W HPP +EIYR+  +S
Sbjct: 346 ELDTWYHSPYPEEYARLGRLYMCEFCLKYMKSQTILRRHMAKCVWKHPPGDEIYRKGSIS 405

Query: 789 VFEVDGNMSKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVLTKNDEKGCHLVGYFSKEKL 848
           VFEVDG  +KIYCQNLCLLAKLFLDHKTLYYDVEPFLFYV+T+ D  GCHL+GYFSKEK 
Sbjct: 406 VFEVDGKKNKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVMTEADNTGCHLIGYFSKEKN 465

Query: 849 CQQKYNVSCIMIMPQHQRQGFGRFLIDFSYLLSRREGQAGSPEKPLSDLGRLSYLAYWKS 908
               YNVSCI+ MPQ+ RQG+G+ LIDFSYLLS+ E + GSPE+PLSDLG +SY +YWK 
Sbjct: 466 SFLNYNVSCILTMPQYMRQGYGKMLIDFSYLLSKVEEKVGSPERPLSDLGLISYRSYWKE 525

Query: 909 VILEYLYHHHERHISIKAISRATGMCPHDIATTLQHLHMIDKRDGRFVIIRREKLILSHM 968
           V+L YL++   + ISIK IS+ T + P DI +TLQ L M+    G+ ++++R+ LI   +
Sbjct: 526 VLLRYLHNFQGKEISIKEISQETAVNPVDIVSTLQALQMLKYWKGKHLVLKRQDLIDEWI 585

Query: 969 EKLKTCSRANE-LDPDSLRWTP 989
            K    S +N+ +DP  L+WTP
Sbjct: 586 AKEAKRSNSNKTMDPSCLKWTP 607


>gi|226371636 MYST histone acetyltransferase 1 isoform 1 [Homo
           sapiens]
          Length = 458

 Score =  290 bits (743), Expect = 8e-78
 Identities = 140/272 (51%), Positives = 185/272 (68%), Gaps = 1/272 (0%)

Query: 718 RYPSVIEFGKYEIQTWYSSPYPQEYARLPKLYLCEFCLKYMKSKNILLRHSKKCGWFHPP 777
           +Y   I  G YEI  WY SP+P++Y + PKL+LCE+CLKYMK +     H  +C W  PP
Sbjct: 177 KYVDKIHIGNYEIDAWYFSPFPEDYGKQPKLWLCEYCLKYMKYEKSYRFHLGQCQWRQPP 236

Query: 778 ANEIYRRKDLSVFEVDGNMSKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVLTKNDEKGC 837
             EIYR+ ++SV+EVDG   KIYCQNLCLLAKLFLDHKTLY+DVEPF+FY+LT+ D +G 
Sbjct: 237 GKEIYRKSNISVYEVDGKDHKIYCQNLCLLAKLFLDHKTLYFDVEPFVFYILTEVDRQGA 296

Query: 838 HLVGYFSKEKLCQQKYNVSCIMIMPQHQRQGFGRFLIDFSYLLSRREGQAGSPEKPLSDL 897
           H+VGYFSKEK      NV+CI+ +P +QR+G+G+FLI FSY LS+ E   GSPEKPLSDL
Sbjct: 297 HIVGYFSKEKESPDGNNVACILTLPPYQRRGYGKFLIAFSYELSKLESTVGSPEKPLSDL 356

Query: 898 GRLSYLAYWKSVILEYLYHHHERHISIKAISRATGMCPHDIATTLQHLHMIDKRDGRFVI 957
           G+LSY +YW  V+LE L       +SIK +S+ T +  +DI +TLQ L+M+    G+ VI
Sbjct: 357 GKLSYRSYWSWVLLEIL-RDFRGTLSIKDLSQMTSITQNDIISTLQSLNMVKYWKGQHVI 415

Query: 958 IRREKLILSHMEKLKTCSRANELDPDSLRWTP 989
               KL+  H++  +       +D   L+W P
Sbjct: 416 CVTPKLVEEHLKSAQYKKPPITVDSVCLKWAP 447


>gi|226371638 MYST histone acetyltransferase 1 isoform 2 [Homo
           sapiens]
          Length = 467

 Score =  285 bits (729), Expect = 3e-76
 Identities = 136/252 (53%), Positives = 178/252 (70%), Gaps = 1/252 (0%)

Query: 718 RYPSVIEFGKYEIQTWYSSPYPQEYARLPKLYLCEFCLKYMKSKNILLRHSKKCGWFHPP 777
           +Y   I  G YEI  WY SP+P++Y + PKL+LCE+CLKYMK +     H  +C W  PP
Sbjct: 177 KYVDKIHIGNYEIDAWYFSPFPEDYGKQPKLWLCEYCLKYMKYEKSYRFHLGQCQWRQPP 236

Query: 778 ANEIYRRKDLSVFEVDGNMSKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVLTKNDEKGC 837
             EIYR+ ++SV+EVDG   KIYCQNLCLLAKLFLDHKTLY+DVEPF+FY+LT+ D +G 
Sbjct: 237 GKEIYRKSNISVYEVDGKDHKIYCQNLCLLAKLFLDHKTLYFDVEPFVFYILTEVDRQGA 296

Query: 838 HLVGYFSKEKLCQQKYNVSCIMIMPQHQRQGFGRFLIDFSYLLSRREGQAGSPEKPLSDL 897
           H+VGYFSKEK      NV+CI+ +P +QR+G+G+FLI FSY LS+ E   GSPEKPLSDL
Sbjct: 297 HIVGYFSKEKESPDGNNVACILTLPPYQRRGYGKFLIAFSYELSKLESTVGSPEKPLSDL 356

Query: 898 GRLSYLAYWKSVILEYLYHHHERHISIKAISRATGMCPHDIATTLQHLHMIDKRDGRFVI 957
           G+LSY +YW  V+LE L       +SIK +S+ T +  +DI +TLQ L+M+    G+ VI
Sbjct: 357 GKLSYRSYWSWVLLEIL-RDFRGTLSIKDLSQMTSITQNDIISTLQSLNMVKYWKGQHVI 415

Query: 958 IRREKLILSHME 969
               KL+  H++
Sbjct: 416 CVTPKLVEEHLK 427


>gi|36287069 K(lysine) acetyltransferase 5 isoform 1 [Homo sapiens]
          Length = 546

 Score =  281 bits (720), Expect = 4e-75
 Identities = 140/272 (51%), Positives = 183/272 (67%), Gaps = 7/272 (2%)

Query: 723 IEFGKYEIQTWYSSPYPQEYARLPKLYLCEFCLKYMKSKNILLRHSKKCGWFHPPANEIY 782
           IE G++ ++ WY SPYPQE   LP LYLCEFCLKY +S   L RH  KC   HPP NEIY
Sbjct: 268 IELGRHRLKPWYFSPYPQELTTLPVLYLCEFCLKYGRSLKCLQRHLTKCDLRHPPGNEIY 327

Query: 783 RRKDLSVFEVDGNMSKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVLTKNDEKGCHLVGY 842
           R+  +S FE+DG  +K Y QNLCLLAK FLDHKTLYYD +PFLFYV+T+ D KG H+VGY
Sbjct: 328 RKGTISFFEIDGRKNKSYSQNLCLLAKCFLDHKTLYYDTDPFLFYVMTEYDCKGFHIVGY 387

Query: 843 FSKEKLCQQKYNVSCIMIMPQHQRQGFGRFLIDFSYLLSRREGQAGSPEKPLSDLGRLSY 902
           FSKEK   + YNV+CI+ +P +QR+G+G+ LI+FSY LS+ EG+ G+PEKPLSDLG LSY
Sbjct: 388 FSKEKESTEDYNVACILTLPPYQRRGYGKLLIEFSYELSKVEGKTGTPEKPLSDLGLLSY 447

Query: 903 LAYWKSVILEYLY----HHHER-HISIKAISRATGMCPHDIATTLQHLHMIDKRDGRFVI 957
            +YW   ILE L        ER  I+I  IS  T +   D+ +TLQ+L++I+   G++++
Sbjct: 448 RSYWSQTILEILMGLKSESGERPQITINEISEITSIKKEDVISTLQYLNLINYYKGQYIL 507

Query: 958 IRREKLILSHMEKLKTCSRANELDPDSLRWTP 989
              E ++  H   +    R   +D   L +TP
Sbjct: 508 TLSEDIVDGHERAM--LKRLLRIDSKCLHFTP 537


>gi|36287060 K(lysine) acetyltransferase 5 isoform 3 [Homo sapiens]
          Length = 461

 Score =  281 bits (720), Expect = 4e-75
 Identities = 140/272 (51%), Positives = 183/272 (67%), Gaps = 7/272 (2%)

Query: 723 IEFGKYEIQTWYSSPYPQEYARLPKLYLCEFCLKYMKSKNILLRHSKKCGWFHPPANEIY 782
           IE G++ ++ WY SPYPQE   LP LYLCEFCLKY +S   L RH  KC   HPP NEIY
Sbjct: 183 IELGRHRLKPWYFSPYPQELTTLPVLYLCEFCLKYGRSLKCLQRHLTKCDLRHPPGNEIY 242

Query: 783 RRKDLSVFEVDGNMSKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVLTKNDEKGCHLVGY 842
           R+  +S FE+DG  +K Y QNLCLLAK FLDHKTLYYD +PFLFYV+T+ D KG H+VGY
Sbjct: 243 RKGTISFFEIDGRKNKSYSQNLCLLAKCFLDHKTLYYDTDPFLFYVMTEYDCKGFHIVGY 302

Query: 843 FSKEKLCQQKYNVSCIMIMPQHQRQGFGRFLIDFSYLLSRREGQAGSPEKPLSDLGRLSY 902
           FSKEK   + YNV+CI+ +P +QR+G+G+ LI+FSY LS+ EG+ G+PEKPLSDLG LSY
Sbjct: 303 FSKEKESTEDYNVACILTLPPYQRRGYGKLLIEFSYELSKVEGKTGTPEKPLSDLGLLSY 362

Query: 903 LAYWKSVILEYLY----HHHER-HISIKAISRATGMCPHDIATTLQHLHMIDKRDGRFVI 957
            +YW   ILE L        ER  I+I  IS  T +   D+ +TLQ+L++I+   G++++
Sbjct: 363 RSYWSQTILEILMGLKSESGERPQITINEISEITSIKKEDVISTLQYLNLINYYKGQYIL 422

Query: 958 IRREKLILSHMEKLKTCSRANELDPDSLRWTP 989
              E ++  H   +    R   +D   L +TP
Sbjct: 423 TLSEDIVDGHERAM--LKRLLRIDSKCLHFTP 452


>gi|36287049 K(lysine) acetyltransferase 5 isoform 2 [Homo sapiens]
          Length = 513

 Score =  281 bits (720), Expect = 4e-75
 Identities = 140/272 (51%), Positives = 183/272 (67%), Gaps = 7/272 (2%)

Query: 723 IEFGKYEIQTWYSSPYPQEYARLPKLYLCEFCLKYMKSKNILLRHSKKCGWFHPPANEIY 782
           IE G++ ++ WY SPYPQE   LP LYLCEFCLKY +S   L RH  KC   HPP NEIY
Sbjct: 235 IELGRHRLKPWYFSPYPQELTTLPVLYLCEFCLKYGRSLKCLQRHLTKCDLRHPPGNEIY 294

Query: 783 RRKDLSVFEVDGNMSKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVLTKNDEKGCHLVGY 842
           R+  +S FE+DG  +K Y QNLCLLAK FLDHKTLYYD +PFLFYV+T+ D KG H+VGY
Sbjct: 295 RKGTISFFEIDGRKNKSYSQNLCLLAKCFLDHKTLYYDTDPFLFYVMTEYDCKGFHIVGY 354

Query: 843 FSKEKLCQQKYNVSCIMIMPQHQRQGFGRFLIDFSYLLSRREGQAGSPEKPLSDLGRLSY 902
           FSKEK   + YNV+CI+ +P +QR+G+G+ LI+FSY LS+ EG+ G+PEKPLSDLG LSY
Sbjct: 355 FSKEKESTEDYNVACILTLPPYQRRGYGKLLIEFSYELSKVEGKTGTPEKPLSDLGLLSY 414

Query: 903 LAYWKSVILEYLY----HHHER-HISIKAISRATGMCPHDIATTLQHLHMIDKRDGRFVI 957
            +YW   ILE L        ER  I+I  IS  T +   D+ +TLQ+L++I+   G++++
Sbjct: 415 RSYWSQTILEILMGLKSESGERPQITINEISEITSIKKEDVISTLQYLNLINYYKGQYIL 474

Query: 958 IRREKLILSHMEKLKTCSRANELDPDSLRWTP 989
              E ++  H   +    R   +D   L +TP
Sbjct: 475 TLSEDIVDGHERAM--LKRLLRIDSKCLHFTP 504


>gi|5454004 D4, zinc and double PHD fingers family 2 [Homo sapiens]
          Length = 391

 Score =  135 bits (340), Expect = 4e-31
 Identities = 67/147 (45%), Positives = 85/147 (57%), Gaps = 15/147 (10%)

Query: 194 SLPPVSLLPHEKDQPR-------ADPIPICSFCLGTKESNREK-KPEELLSCADCGSSGH 245
           S PP  +    ++Q         A P   C FCLG  + N++  +PEEL+SC+DCG SGH
Sbjct: 244 SQPPTPVSQRSEEQKSKKGPDGLALPNNYCDFCLGDSKINKKTGQPEELVSCSDCGRSGH 303

Query: 246 PSCLKFCPELTTNVKALRWQCIECKTCSACRVQGRNADNMLFCDSCDRGFHMECCDPPLS 305
           PSCL+F P +   VK  RWQCIECK C+ C     N D +LFCD CDRG+HM C  P +S
Sbjct: 304 PSCLQFTPVMMAAVKTYRWQCIECKCCNICGT-SENDDQLLFCDDCDRGYHMYCLTPSMS 362

Query: 306 RMPKGMWICQVCRPKKKGRKLLHEKAA 332
             P+G W C +C        LL EKA+
Sbjct: 363 EPPEGSWSCHLC------LDLLKEKAS 383


>gi|205830434 D4, zinc and double PHD fingers family 1 isoform c
           [Homo sapiens]
          Length = 332

 Score =  134 bits (336), Expect = 1e-30
 Identities = 60/115 (52%), Positives = 73/115 (63%), Gaps = 5/115 (4%)

Query: 205 KDQPRADPIP--ICSFCLGTKESNREKKPEELLSCADCGSSGHPSCLKFCPELTTNVKAL 262
           K  P    IP   C FCLG   S +   PE+L+SCADCG SGHPSCL+F   +T  V+  
Sbjct: 206 KKAPDGTVIPNGYCDFCLGG--SKKTGCPEDLISCADCGRSGHPSCLQFTVNMTAAVRTY 263

Query: 263 RWQCIECKTCSACRVQGRNADNMLFCDSCDRGFHMECCDPPLSRMPKGMWICQVC 317
           RWQCIECK+CS C     N D +LFCD CDRG+HM C  PP++  P+G W C +C
Sbjct: 264 RWQCIECKSCSLCGT-SENDDQLLFCDDCDRGYHMYCLSPPMAEPPEGSWSCHLC 317


>gi|205830430 D4, zinc and double PHD fingers family 1 isoform a
           [Homo sapiens]
          Length = 414

 Score =  134 bits (336), Expect = 1e-30
 Identities = 60/115 (52%), Positives = 73/115 (63%), Gaps = 5/115 (4%)

Query: 205 KDQPRADPIP--ICSFCLGTKESNREKKPEELLSCADCGSSGHPSCLKFCPELTTNVKAL 262
           K  P    IP   C FCLG   S +   PE+L+SCADCG SGHPSCL+F   +T  V+  
Sbjct: 288 KKAPDGTVIPNGYCDFCLGG--SKKTGCPEDLISCADCGRSGHPSCLQFTVNMTAAVRTY 345

Query: 263 RWQCIECKTCSACRVQGRNADNMLFCDSCDRGFHMECCDPPLSRMPKGMWICQVC 317
           RWQCIECK+CS C     N D +LFCD CDRG+HM C  PP++  P+G W C +C
Sbjct: 346 RWQCIECKSCSLCGT-SENDDQLLFCDDCDRGYHMYCLSPPMAEPPEGSWSCHLC 399


>gi|205830432 D4, zinc and double PHD fingers family 1 isoform b
           [Homo sapiens]
          Length = 380

 Score =  130 bits (327), Expect = 1e-29
 Identities = 67/163 (41%), Positives = 85/163 (52%), Gaps = 16/163 (9%)

Query: 169 GPQYRVNYGSLDGKGAPQYPSAFPSSL---PPVSLLPHEKDQPRADPIP--ICSFCLGTK 223
           G + R +  SL+ +  P     F   L   P        K  P    IP   C FCLG  
Sbjct: 205 GLRKRQDTASLEDRDKPYVCDKFYKELAWVPEAQRKHTAKKAPDGTVIPNGYCDFCLGG- 263

Query: 224 ESNREKKPEELLSCADCGSSGHPSCLKFCPELTTNVKALRWQCIECKTCSACRVQGRNA- 282
            S +   PE+L+SCADCG SGHPSCL+F   +T  V+  RWQCIECK+CS C     +  
Sbjct: 264 -SKKTGCPEDLISCADCGRSGHPSCLQFTVNMTAAVRTYRWQCIECKSCSLCGTSENDGA 322

Query: 283 --------DNMLFCDSCDRGFHMECCDPPLSRMPKGMWICQVC 317
                   D +LFCD CDRG+HM C  PP++  P+G W C +C
Sbjct: 323 SWAGLTPQDQLLFCDDCDRGYHMYCLSPPMAEPPEGSWSCHLC 365


>gi|194328736 PHD finger protein 10 isoform b [Homo sapiens]
          Length = 496

 Score =  121 bits (304), Expect = 6e-27
 Identities = 56/124 (45%), Positives = 74/124 (59%), Gaps = 8/124 (6%)

Query: 207 QPRADPIPICSFCLGTKESNREKKPEELLSCADCGSSGHPSCLKFCPELTTNVKALRWQC 266
           +P+  P  IC  CL  KESN++ K E L+ C+ C +SGHPSCL    EL + +K   WQC
Sbjct: 369 KPKVIPNAICGICLKGKESNKKGKAESLIHCSQCENSGHPSCLDMTMELVSMIKTYPWQC 428

Query: 267 IECKTCSACRVQGRNADNMLFCDSCDRGFHMECCDPPLSRMPKGMWICQVCR-----PKK 321
           +ECKTC  C  Q  + + M+FCD CDRG+H  C    L  +P G WIC  C+     P+K
Sbjct: 429 MECKTCIICG-QPHHEEEMMFCDMCDRGYHTFCVG--LGAIPSGRWICDCCQRAPPTPRK 485

Query: 322 KGRK 325
            GR+
Sbjct: 486 VGRR 489


>gi|194328734 PHD finger protein 10 isoform a [Homo sapiens]
          Length = 498

 Score =  121 bits (304), Expect = 6e-27
 Identities = 56/124 (45%), Positives = 74/124 (59%), Gaps = 8/124 (6%)

Query: 207 QPRADPIPICSFCLGTKESNREKKPEELLSCADCGSSGHPSCLKFCPELTTNVKALRWQC 266
           +P+  P  IC  CL  KESN++ K E L+ C+ C +SGHPSCL    EL + +K   WQC
Sbjct: 371 KPKVIPNAICGICLKGKESNKKGKAESLIHCSQCENSGHPSCLDMTMELVSMIKTYPWQC 430

Query: 267 IECKTCSACRVQGRNADNMLFCDSCDRGFHMECCDPPLSRMPKGMWICQVCR-----PKK 321
           +ECKTC  C  Q  + + M+FCD CDRG+H  C    L  +P G WIC  C+     P+K
Sbjct: 431 MECKTCIICG-QPHHEEEMMFCDMCDRGYHTFCVG--LGAIPSGRWICDCCQRAPPTPRK 487

Query: 322 KGRK 325
            GR+
Sbjct: 488 VGRR 491


>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
            [Homo sapiens]
          Length = 899

 Score =  102 bits (255), Expect = 3e-21
 Identities = 121/581 (20%), Positives = 252/581 (43%), Gaps = 46/581 (7%)

Query: 960  REKLILSHMEKLKTCSRANELDPDSLRWTPILISNAAVSEEEREAEKEAERLMEQASCWE 1019
            +EKL L+  EK +      EL    L     L+     +  + E  ++ E L EQ     
Sbjct: 231  QEKLPLAESEKSEIQLNVKELKR-KLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIR 289

Query: 1020 KEEQEILSTRANSRQSPAKVQSKNKYLHSPESRPVTGERGQLLELSKESSEEEEEEEDEE 1079
            K+E+++       R+   K++ + + +   E R    E+ +L E  KE  E++E  E EE
Sbjct: 290  KQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEK-ELREQEKELREQKELREQEE 348

Query: 1080 E-EEEEEEEEEDEEEEEEEEEE---EEEENIQSSPPRLTKPQSVAIKRKRPFV----LKK 1131
            + +E+EE+  E EE+  E+EE+   +EE   +       + Q +  + +R +     L++
Sbjct: 349  QMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLRE 408

Query: 1132 KRGRKRRRINSSVTTETISETTEVLNEPFDNSDEERPMPQLEPTCEIEV---EEDGRKPV 1188
            K  R R +       E + E  ++  +     D+E  M + E   E E    EE+     
Sbjct: 409  KEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMRE 468

Query: 1189 LRKAFQHQPGKKRQTEEEEGKDNHCFKNADPC--RNNMNDDSSNLKEGSKDNPEPLKCKQ 1246
              +  Q Q     + EE+E +     +  +    +  M +    + E  +   +    ++
Sbjct: 469  QEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQ---EE 525

Query: 1247 VWPKGTKRGLSKWRQNKERKTGFKLNLYTPPETPMEP---DEQVTVEEQKETSEGKT--S 1301
            +W +  K     WRQ K R+   ++          E    D++  +E++ +  E KT   
Sbjct: 526  MWGQEKK----MWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQ 581

Query: 1302 PSPIRIEEEVKETGEALLPQEENRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEE 1361
               +R EE ++E  + +  +EE  RE+    +       ++ E+ + + EE+ +E+EE+ 
Sbjct: 582  EEKMREEERMREREKKMREEEEMMREQE-EKMQEQEEKMQEQEEKMWEQEEKMQEQEEKM 640

Query: 1362 EEEEEEEGEEEEGGGNVEKDPDGAK-----SQEKEEPEISTEKEDSARLDDHEEEEEEDE 1416
             E+EE+  E+EE     ++ P+  +      + +E+ ++  ++E     +  E++ +E E
Sbjct: 641  WEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQE 700

Query: 1417 EPSHNEDHDADDEDDSHMESAEVEKEELPRESFKEVLENQETFLDLNVQPGHSNPEVLMD 1476
            + + +++   ++E     E    E+EE+ RE  +++ E +E   +   +      ++   
Sbjct: 701  KKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMW-- 758

Query: 1477 CGVDLTASCNSEPKELAGDPEAVPESDEEPPPGEQAQKQDQ 1517
                       E +E   + + +PE  E+    E+ Q+Q++
Sbjct: 759  -----------EQEEKMWEQQRLPEQKEKLWEHEKMQEQEK 788



 Score = 76.3 bits (186), Expect = 3e-13
 Identities = 98/459 (21%), Positives = 196/459 (42%), Gaps = 64/459 (13%)

Query: 999  EEEREAEKEAERLMEQASCWEKEEQEILSTRANSRQSPAKVQSKNKYLHSPESRPVTGER 1058
            ++ER  EKE ER+ EQ   WE+ E+          +   K+Q + K     E +    ER
Sbjct: 402  QDERLREKE-ERMREQEKMWEQVEK---------MREEKKMQEQEKKTRDQEEKMQEEER 451

Query: 1059 GQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEE---------EEENIQSS 1109
              + E  K+  EEEE   ++EE+ +++EE   E+EE+E +++          E+E +Q  
Sbjct: 452  --IREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQ 509

Query: 1110 PPRLTKPQSVAIKRKRPFVLKKKRGRKRRRINSSVTTETISETTEVLNEPFDNSDEERPM 1169
              ++ + +     ++  +  +KK  R+ +        + + E  E +       D+E+ M
Sbjct: 510  EEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQE---DQMWEQEEKMR------DQEQKM 560

Query: 1170 PQLEPTCEIEVEEDGRKPVLRKAFQHQPGKKRQTEEEEGKDNHCFKNADPCRNNMNDDSS 1229
               E   E + +E  +K   ++    +  + R+ E++  ++    +  +       +   
Sbjct: 561  WDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQ 620

Query: 1230 NLKEGSKDNPEPLKCKQ--VWPKGTKRGLSK---WRQNKERKTGFKL---NLYTPPETPM 1281
              +E   +  E ++ ++  +W +  K    +   W Q +  +   KL         E   
Sbjct: 621  EQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQ 680

Query: 1282 EPDEQVTVEEQKETS----EGKT-SPSPIRIEEEVKETGEALLPQEENRREETCAPVSPN 1336
            E +E++  +E+ E      E KT     +R EE ++E  + +  +EE  RE+        
Sbjct: 681  EQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQ-------- 732

Query: 1337 TSPGEKPEDDLIKPEEEEEEEEEEEE----EEEEEEGEEEEGGGNVEKDPDGAKSQEKEE 1392
                E+   +  +  +E+EEE  E+E    E+EE+  E++      EK  +  K QE+E+
Sbjct: 733  ----EEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEK 788

Query: 1393 PEISTEKEDSARLDDHEEEEEEDEEPSHNEDHDADDEDD 1431
                 E+E+  R  D EE+    EE    ++     +++
Sbjct: 789  ---IWEQEEKMR--DQEEKMRGQEEKMRGQEEKMRGQEE 822



 Score = 73.9 bits (180), Expect = 1e-12
 Identities = 111/576 (19%), Positives = 240/576 (41%), Gaps = 59/576 (10%)

Query: 995  AAVSEEEREAEKEAERLMEQASCWEKEEQEILSTRANSRQSPAKVQSKNKYLHSPESRPV 1054
            +AVS   ++A++  E L ++      E      T    ++  A++Q K     S +S   
Sbjct: 186  SAVSTRHKKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLPLAESEKSE-- 243

Query: 1055 TGERGQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLT 1114
                   ++L+ +  + + E       + +    ++E   +EEE  E+E+ I+    ++ 
Sbjct: 244  -------IQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMW 296

Query: 1115 KPQS-VAIKRKRPFVLKKKRGRKRRRINSSVTTETISETTEVLNEPFDNSDEERPMPQLE 1173
            + +  +  +  +    ++K  R+ +R+      + + E  + L E  +  ++E  M + E
Sbjct: 297  RQEERLREQEGKMREQEEKMWRQEKRLREQ--EKELREQEKELREQKELREQEEQMQEQE 354

Query: 1174 PTC---EIEVEEDGRKPVLRKAFQHQPGKKRQTEEEEGKDNHCFKNADPCRNNMNDDSSN 1230
                  E ++ E   K   ++    +  K+ + +E++ +D             M +    
Sbjct: 355  EKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQ---------EERMWEQDER 405

Query: 1231 LKEGSKDNPEPLKCKQVWPKGTKRGLSKWRQNKERKTGFKLNLYTPPETPMEPDEQVTVE 1290
            L+E  +   E    +++W +  K    K  Q +E+KT          E  M+ +E++   
Sbjct: 406  LREKEERMREQ---EKMWEQVEKMREEKKMQEQEKKT-------RDQEEKMQEEERIRER 455

Query: 1291 EQKETSEGKTSPSPIRIEEEVKETGEALLPQEENRREETCAPVSPNTSPGEKPEDDLIKP 1350
            E+K   E          EE ++E  E +  QEEN  E+          P +K   + +  
Sbjct: 456  EKKMREE----------EETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQK---EKLWE 502

Query: 1351 EEEEEEEEEEEEEEEEEEGEEEEGGGNVEKDPDGAKSQEKEEPEISTE---KEDSARLDD 1407
            +E+ +E+EE+  E+EE+  ++EE  G  +K     K +E+E+     E   ++   ++ D
Sbjct: 503  QEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWD 562

Query: 1408 HEEE-----EEEDEEPSHNEDHDADDEDDSHMESAEVEKEELPRESFKEVLENQETFLDL 1462
             EE      +E++++    E+   ++E     E    E+EE+ RE  +E ++ QE  +  
Sbjct: 563  QEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQ-EEKMQEQEEKMQE 621

Query: 1463 NVQPGHSNPEVLMDCGVDLTASCNS--EPKELAGDPEAVPESDEEPPPGEQAQKQDQKNS 1520
              +      E + +    +        E +E   + + +PE  E+    E+ Q+Q++   
Sbjct: 622  QEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQE 681

Query: 1521 KEVDT-EFKEGNPATMEIDSETVQAVQSLTQESSEQ 1555
            +E    E ++    T E + +T    +   +ES  +
Sbjct: 682  QEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMRE 717



 Score = 73.2 bits (178), Expect = 3e-12
 Identities = 98/502 (19%), Positives = 202/502 (40%), Gaps = 60/502 (11%)

Query: 958  IRREKLILSHMEKLKTCSRANELDPDSLRWTPILISNAAVSEEEREAEKEAERLMEQASC 1017
            +R ++ +   +EK++   +  E +  +      +     + E E++  +E E + EQ   
Sbjct: 413  MREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEK 472

Query: 1018 WEKEEQEILSTRANSRQSPAKVQSKNKYLHSPESRPVTGERGQLLELSKESSEEEEEEED 1077
             +K+E+ +        Q              PE +    E+ ++ E  ++  E+EE+  D
Sbjct: 473  MQKQEENMWEQEEKEWQQQ----------RLPEQKEKLWEQEKMQEQEEKIWEQEEKIRD 522

Query: 1078 EEE---------EEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQSVAIKRKRPFV 1128
            +EE          +E+  E+ED+  E+EE+  ++E+ +     R+ K      K+     
Sbjct: 523  QEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWD-- 580

Query: 1129 LKKKRGRKRRRINSSVTTETISETTEVLNEPFDNSDEERPMPQLEPTCEIEVEEDGRKPV 1188
             ++++ R+  R+      + + E  E++ E  +   E+    Q +     E EE      
Sbjct: 581  -QEEKMREEERMRER--EKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEK----- 632

Query: 1189 LRKAFQHQPGKKRQTEEE--EGKDNHCFKNADPCRNNMNDDSSNLKEGSKDNPEPLKCKQ 1246
                 Q Q  K  + EE+  E ++    +   P +     +   ++E  K   +  K   
Sbjct: 633  ----MQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEK--- 685

Query: 1247 VWPKGTKRGLSKWRQNKERKTGFKLNLYTPP-----ETPMEPDEQVTVEEQKETSEGKTS 1301
            +W +     + K  Q +E+KT  +  +         E  M  +E++  E++++  E +  
Sbjct: 686  IWEQ---EKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEK 742

Query: 1302 PSPIRIEEEVKETGEALLPQEENRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEE 1361
                  EEE+ E  E +  QEE   E+   P         +   +  K  E+EE+  ++E
Sbjct: 743  MQ--EQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQE 800

Query: 1362 E-----------EEEEEEGEEEEGGGNVEKD-PDGAKSQEKEEPEISTEKEDSARLDDHE 1409
            E           +EE+  G+EE+  G  EK      K   +EE     E++   ++   E
Sbjct: 801  EKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQE 860

Query: 1410 EEEEEDEEPSHNEDHDADDEDD 1431
            E+  E EE    ++    ++++
Sbjct: 861  EKMREQEEKMRGQEEKMREQEE 882



 Score = 71.6 bits (174), Expect = 7e-12
 Identities = 85/445 (19%), Positives = 194/445 (43%), Gaps = 38/445 (8%)

Query: 999  EEEREAEKEAERLMEQASCWEKEEQEILSTRANSRQSPA----KVQSKNKYLHSPESR-- 1052
            EEE   E+E +   ++ + WE+EE+E    R   ++       K+Q + + +   E +  
Sbjct: 462  EEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIR 521

Query: 1053 ---PVTGERGQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSS 1109
                + G+  ++    K   +E++  E EE+  ++E++  D+EE  E++ +E+E+     
Sbjct: 522  DQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQ 581

Query: 1110 PPRLTKPQSVAIKRKRPFVLKKKRGRKRRRINSSVTTETISETTEVLNEPFDN--SDEER 1167
              ++ + + +  + K+  + +++   + +        E + E  E + E  +     EE+
Sbjct: 582  EEKMREEERMREREKK--MREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEK 639

Query: 1168 PMPQLEPTCEIEVE--EDGRKPVLR-KAFQH---QPGKKRQTEEEEGKDNHCFKNADPCR 1221
               Q E   E E +  E  R P  + K ++H   Q  +K Q +EE+  +    +     +
Sbjct: 640  MWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQ 699

Query: 1222 NNMNDDSSNLKEGSKDNPEPLKCKQVWPKGTKRGLSKWRQNKERKTGFKLNLYTPPETPM 1281
                 D   ++E         K ++   +  +    K ++ +E+    +  ++   E   
Sbjct: 700  EKKTWDQEKMREEESMREREKKMREE-EEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMW 758

Query: 1282 EPDEQVTVEEQ-KETSEGKTSPSPIRIEEEVKETGEALLPQEENRREETCAPVSPNTSPG 1340
            E +E++  +++  E  E       ++ +E++ E  E +  QEE  R +            
Sbjct: 759  EQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQ---------EEK 809

Query: 1341 EKPEDDLIKPEEEEEEEEEEEEEEEEEE--GEEEEGGGNVEKDPDGAKSQEKEEPEISTE 1398
             + +++ ++ +EE+   +EE+   +EE+  G+EE+  G  EK  +  + QE++       
Sbjct: 810  MRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEK------M 863

Query: 1399 KEDSARLDDHEEEEEEDEEPSHNED 1423
            +E   ++   EE+  E EE    ++
Sbjct: 864  REQEEKMRGQEEKMREQEEKMRGQE 888



 Score = 46.6 bits (109), Expect = 3e-04
 Identities = 28/120 (23%), Positives = 58/120 (48%), Gaps = 6/120 (5%)

Query: 1000 EEREAEKEAERLMEQASCWEKEE------QEILSTRANSRQSPAKVQSKNKYLHSPESRP 1053
            E++E   E E++ EQ   WE+EE      +++       R    K++ + + +   E + 
Sbjct: 772  EQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKM 831

Query: 1054 VTGERGQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRL 1113
               E     +  K   +EE+ EE  + +EE+  E+E++   +EE+  E+EE ++    ++
Sbjct: 832  WGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQEEKMRGQEEKI 891


>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
          Length = 1020

 Score =  101 bits (252), Expect = 7e-21
 Identities = 132/613 (21%), Positives = 248/613 (40%), Gaps = 54/613 (8%)

Query: 1038 KVQSKNKYLHSPESRPV-TGERGQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEE 1096
            K + K K +   E   V   E+ +  ++++E +EEEE+E  EEE +EEE  EE+E E  E
Sbjct: 439  KSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGE 498

Query: 1097 EEEEEEEENIQSSPPRLTKPQSVAIKRKRPFVLKKKRGRKRRRINSSVTTETISETTEVL 1156
            EE +       +SP +  K   V  + K P   K     + +       +    ++ E  
Sbjct: 499  EETKSPPAEEAASPEKEAK-SPVKEEAKSPAEAKSPEKEEAK-------SPAEVKSPEKA 550

Query: 1157 NEPFDNSDEERPMPQLEPTCEIEVEEDGRKPVLRKAFQHQPGKKRQTEEEEGKDNHCFKN 1216
              P   + EE   P   P  +   +E+ + P   K+    P K +   +EE K     K+
Sbjct: 551  KSP---AKEEAKSP---PEAKSPEKEEAKSPAEVKS----PEKAKSPAKEEAKSPAEAKS 600

Query: 1217 ADPCRNNMNDDSSNLKEGSKDNPEPLKCKQVWPKGTKRGLSKWRQNKERKTGFKLNLYTP 1276
             +  ++ + +++ +  E      E  K         K   +K    +E K+  K    +P
Sbjct: 601  PEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEK---AKSPTKEEAKSPEKAK--SP 655

Query: 1277 PETPMEPDEQVTVEEQKETSEGKTSPSPIRIEEEVKETGEALLPQEENRREETCAPVSPN 1336
             +   +  E+     + E    + + SP++ E +  E  ++ + +E    E+  +PV   
Sbjct: 656  EKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEE 715

Query: 1337 TSPGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGEEEEGGGNVEKDPDGAKSQEKEEPEIS 1396
                EK +     P +EE +  E+ +   +EE +  E      K P+ AK+ + + PE  
Sbjct: 716  AKSPEKAK----SPVKEEAKTPEKAKSPVKEEAKSPEKA----KSPEKAKTLDVKSPEAK 767

Query: 1397 TEKEDSARLDDHEEEEEEDEEPSHNEDHDADDEDDSHMESAEVEKEELP-RESFKEVLEN 1455
            T  ++ AR    ++  E+ + P   E    +       E A+  ++E+P +E  K  ++ 
Sbjct: 768  TPAKEEAR-SPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKE 826

Query: 1456 QETFLDLNVQPGHSNPEVLMDCGVDLTASCNSEPKELAGDPEA-VPESDEEPPPG----- 1509
            +E   ++ V+      E         T       KE A   EA  P+ +E+  P      
Sbjct: 827  EEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPK 886

Query: 1510 ---EQAQKQDQKNSKEVDTEFKEGNPATMEIDSETVQAVQSLTQESSEQDDTFQDCAETQ 1566
                +A+K++ ++ K+V T  KE  PA +E+  +      +  +E +E      D A+ +
Sbjct: 887  ESKVEAKKEEAEDKKKVPTPEKEA-PAKVEVKED------AKPKEKTEVAKKEPDDAKAK 939

Query: 1567 EACRSLQNYTRADQSPQIATTLDDCQQSDHSSPVSSVHSHPGQSVRSVNSPSVPALENSY 1626
            E  +  +   + + +P+   T ++  +     P +   +       S   PS P  E + 
Sbjct: 940  EPSKPAE---KKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLS-KEPSKPKAEKAE 995

Query: 1627 AQISPDQSAISVP 1639
               S DQ     P
Sbjct: 996  KSSSTDQKDSKPP 1008



 Score = 90.9 bits (224), Expect = 1e-17
 Identities = 113/485 (23%), Positives = 205/485 (42%), Gaps = 48/485 (9%)

Query: 996  AVSEEEREAEKEAE-RLMEQASCWEKEEQ----EILSTRANSRQSPAKVQSKNKYLHSPE 1050
            A S E+ EA+  AE +  E+A    KEE     E  S      +SPA+V+S  K     +
Sbjct: 530  AKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAK 589

Query: 1051 SRPVTGERGQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSP 1110
                +    +  E +K   +EE +   E +   +EE +   E +  E+ +   +    SP
Sbjct: 590  EEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSP 649

Query: 1111 PRLTKPQSVAIKR----KRPFVLKKKRGRKRRRINSSVTTETISETTEVLNEPFDN---S 1163
             +   P+    K     K P   + K   K +   S V  E  +++ E    P      S
Sbjct: 650  EKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAK---SPVKAE--AKSPEKAKSPVKEEAKS 704

Query: 1164 DEERPMPQLEPTCEIEVEEDGRKPVLRKAFQHQPGKKRQTEEEEGKDNHCFKNADPCRNN 1223
             E+   P  E   E +  E  + PV  +A    P K +   +EE K     K+ +  +  
Sbjct: 705  PEKAKSPVKE---EAKSPEKAKSPVKEEA--KTPEKAKSPVKEEAKSPEKAKSPEKAKT- 758

Query: 1224 MNDDSSNLKEGSKDNPEPLKCKQVWPKGTKRGLSKWRQNKER-KTGFKLNLYTPP-ETPM 1281
            ++  S   K  +K+       K  +P+  K  + +  ++ E+ K+  K +   P  E P 
Sbjct: 759  LDVKSPEAKTPAKEEARSPADK--FPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPK 816

Query: 1282 EPDEQVTVEEQKETSEGKTSPSPIRIEEEVKETGEALLPQEENRREETCAPVSPNTSPGE 1341
            + + +  V+E+++  E K    P + EEE          ++++++EE     +P     E
Sbjct: 817  KEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEE 876

Query: 1342 KPEDDLIKPEEEEEEEEEEEEE----------------EEEEEGEEEEGGGNVEKDPDGA 1385
            K E  + KP+E + E ++EE E                E +E+ + +E     +K+PD A
Sbjct: 877  KKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDA 936

Query: 1386 KSQEKEEPEISTEKEDSA--RLDDHEEEEEEDEEPSHNEDHDADDEDDSHMESAEVEKEE 1443
            K++E  +P    EK+++A  + D  EE+ ++ EE    E    +D+     E ++ + E+
Sbjct: 937  KAKEPSKP---AEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEK 993

Query: 1444 LPRES 1448
              + S
Sbjct: 994  AEKSS 998



 Score = 82.8 bits (203), Expect = 3e-15
 Identities = 128/605 (21%), Positives = 230/605 (38%), Gaps = 86/605 (14%)

Query: 982  PDSLRWTPILISNAAVSEEER-----EAEKEAERLMEQASCWEKEEQEILSTRANSRQSP 1036
            P+ L   P + ++  V  EE+     ++EKE   + EQ      EE ++        +  
Sbjct: 423  PEGLPKIPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQT-----EETQVTEEVTEEEEKE 477

Query: 1037 AKVQSKNKYLHSPESRPVTGERGQLLELSKESSEEEEEEEDEEEEE----------EEEE 1086
            AK +   +     E     GE       ++E++  E+E +   +EE          E+EE
Sbjct: 478  AKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEE 537

Query: 1087 EEEDEEEEEEEEEEEEEENIQSSPPRLTKPQSVAIKRKRPFVLK---KKRGRKRRRINSS 1143
             +   E +  E+ +   +    SPP    P+    + K P  +K   K +   +    S 
Sbjct: 538  AKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKE--EAKSPAEVKSPEKAKSPAKEEAKSP 595

Query: 1144 VTTETISETTEVLNEPFDNSDEERPMPQLEPTCEIEVEEDGRKPVLRKAFQHQPGKKRQT 1203
               ++  +    + E   +  E +   + E     EV+   +     K     P K +  
Sbjct: 596  AEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSP 655

Query: 1204 EEEEGKDNHCFKNADPCRNNMNDDSSNLKEGSKDNPE----PLKCKQVWPKGTKRGLSKW 1259
            E+EE K     K+         + + +  +    +PE    P+K +   P+  K  + + 
Sbjct: 656  EKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEE 715

Query: 1260 RQNKER-KTGFKLNLYTP-------------PETPMEPDEQVTV------------EEQK 1293
             ++ E+ K+  K    TP             PE    P++  T+            EE +
Sbjct: 716  AKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEAR 775

Query: 1294 ETSEGKTSPSPIRIEEEVKETGEALLPQEEN---------RREETCAPVSPNTSPGEKPE 1344
              ++     +   ++EEVK   +A  P +E+         ++EE  +PV       EKP+
Sbjct: 776  SPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEE----EKPQ 831

Query: 1345 DDLIKPEEEEEEEEEEEEEEEEEEGEEEEGGGNVEKDPDGAKSQEKEEPEISTEKEDSAR 1404
            +  +K   ++ EEE+     + EE ++ +     +K+    K +EK+EP +   KE    
Sbjct: 832  EVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVE 891

Query: 1405 LDDHEEEEEEDEEPSHNEDHDAD---DEDDSHMESAEVEKEELPRESFKEVLENQETFLD 1461
                EE E++ + P+  ++  A     ED    E  EV K+E      KE  +  E    
Sbjct: 892  A-KKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAE---- 946

Query: 1462 LNVQPGHSNPEVLMDCGVDLTASCNSEPKELAGDPEAVPESDEEP--PPGEQAQKQ---D 1516
                   + PE   D   +       +PK  A   E      +EP  P  E+A+K    D
Sbjct: 947  ----KKEAAPE-KKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTD 1001

Query: 1517 QKNSK 1521
            QK+SK
Sbjct: 1002 QKDSK 1006



 Score = 54.3 bits (129), Expect = 1e-06
 Identities = 61/312 (19%), Positives = 125/312 (40%), Gaps = 42/312 (13%)

Query: 993  SNAAVSEEEREAEKEAERLMEQASCWEK----EEQEILSTRANSRQSPAKVQSKNKYLHS 1048
            + + V EE +  EK    + E+A   EK    E+ + L  ++   ++PAK ++++     
Sbjct: 722  AKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKF 781

Query: 1049 PESRPVTGERGQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQS 1108
            PE      +     E+      +   +ED +  E+E  ++E+ +   +EEE+ +E  ++ 
Sbjct: 782  PEKAKSPVKE----EVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKE 837

Query: 1109 SPPRLTKPQSVAIKRKRPFVLKKKRGRKRRRINSSVTTETISETTE-VLNEPFDNSDEER 1167
             P +  + ++ A     P   +KK  +K            + E  E  + +P ++  E +
Sbjct: 838  PPKKAEEEKAPA----TPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAK 893

Query: 1168 ----------PMPQLEPTCEIEVEEDGRKPVLRKAFQHQPGKKRQTEEEEGKDNHCFKNA 1217
                      P P+ E   ++EV+ED +     +  + +P   +  E  +  +    K A
Sbjct: 894  KEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEK---KEA 950

Query: 1218 DPCRNNMNDDSSNLKE-------GSKDNPEPLKCKQVWPKGTKRGLSKWRQNKERKTGFK 1270
             P + +  ++ +   E        +K++ + L  +   PK  K   S     K+ K    
Sbjct: 951  APEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKDSK---- 1006

Query: 1271 LNLYTPPETPME 1282
                 PPE   E
Sbjct: 1007 -----PPEKATE 1013



 Score = 48.9 bits (115), Expect = 5e-05
 Identities = 69/392 (17%), Positives = 147/392 (37%), Gaps = 34/392 (8%)

Query: 993  SNAAVSEEEREAEKEAERLMEQASCWEKEEQEILSTRANSRQSPAKVQSKNKYLHSPE-S 1051
            + +   EE +  EK      E+A   EK +  + +   +  ++ + V+++ K   SPE +
Sbjct: 638  AKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAK---SPEKA 694

Query: 1052 RPVTGERGQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPP 1111
            +    E  +  E +K   +EE +  ++ +   +EE +  E+ +   +EE +      SP 
Sbjct: 695  KSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPE 754

Query: 1112 RLTKPQSVAIKRKRP-----------FVLKKKRGRKRRRINSSVTTETISETTEVLNEPF 1160
            +       + + K P           F  K K   K    +       + E  +   +  
Sbjct: 755  KAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEI 814

Query: 1161 DNSDEER-PMPQLEPTCEIEVEEDGRK------PVLRKAFQHQPGKKRQTEEEEGKDNHC 1213
               +E + P+ + E   E++V+E  +K      P   K  + +  KK +  ++E      
Sbjct: 815  PKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKV 874

Query: 1214 FKNADPCRNNMNDDSSNLKEGSKDNPEPLKCKQVWPKGTKRGLSKWRQNKERKTGFKLNL 1273
             +  +P      +     K+      E  + K+  P   K   +K    ++ K   K  +
Sbjct: 875  EEKKEPAVEKPKESKVEAKK------EEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEV 928

Query: 1274 YTPPETPMEPDEQVTVEEQKETSEGKTSPSPIRI-EEEVKETGEALLPQEENRREETCAP 1332
                    EPD+    E  K   + + +P      EE+ K+  E    + + + ++    
Sbjct: 929  -----AKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLS 983

Query: 1333 VSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEE 1364
              P+    EK E      +++ +  E+  E++
Sbjct: 984  KEPSKPKAEKAEKSSSTDQKDSKPPEKATEDK 1015



 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 53/244 (21%), Positives = 89/244 (36%), Gaps = 12/244 (4%)

Query: 1307 IEEEVKETGEALLPQEENRREETCA--PVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEE 1364
            +   +K   E  +   E   +ET      +  T   E+  ++  K  +EEE +EEE  EE
Sbjct: 432  VSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEE 491

Query: 1365 EEEEGEEE-------EGGGNVEKDPDGAKSQEKEEP-EISTEKEDSARLDDHEEEEEEDE 1416
            EE EG EE       E   + EK+      +E + P E  + +++ A+     +  E+ +
Sbjct: 492  EEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAK 551

Query: 1417 EPSHNEDHDADDEDDSHMESAEVEKEELPRESFKEVLENQETFLDLNVQPGHSNPEVLMD 1476
             P+  E     +      E A+   E    E  K   + +         P  +   V  +
Sbjct: 552  SPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEE 611

Query: 1477 CGVDLTASCNSEPKELAGDPEAVPESDEEPPPGEQAQKQDQKNSKEVDTEFKEGNPATME 1536
                  A   S  KE A  P  V   ++   P ++  K  +K       E K    A   
Sbjct: 612  --AKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSP 669

Query: 1537 IDSE 1540
            + +E
Sbjct: 670  VKAE 673



 Score = 32.3 bits (72), Expect = 4.9
 Identities = 58/317 (18%), Positives = 111/317 (35%), Gaps = 12/317 (3%)

Query: 371 SPGRGQKTKV---CTTPSSGHAASGKDSSSRLAVTDPTRPGATTKITTTSTYISASTLKV 427
           SP +  K+ V     +P+   +   +++ S   V  P +  +  K    S   + S  K 
Sbjct: 511 SPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKE 570

Query: 428 NKKTKGLIDGLTKFFTPSPDGRRSRGEIIDFSKHYRPRKKVSQKQS-CTSHVLATGTTQK 486
             K+   +    K  +P+ +  +S  E     K   P K+ ++  +   S V     +  
Sbjct: 571 EAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPA 630

Query: 487 LKPPPSSLPPPTPISGQSPSSQKSSTATSSPSPQSSSSQCSVPSLSSLTTNSQLKALFDG 546
               P     PT    +SP   KS     + SP+ + S     + S     S +KA    
Sbjct: 631 EVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKS 690

Query: 547 LSHIYTTQGQSRKKGHPSYAPPKRMRRKTELSST---AKSKAHFFGKRDIRSRFISHSSS 603
                +   +  K    + +P K   +  E + +    ++K     K  ++    S   +
Sbjct: 691 PEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKA 750

Query: 604 SSWGMARGSIFK---AIAHFKRTTFLKKHRMLGRLKYKVTPQMGTPSPGKGSLTDGRIKP 660
            S   A+    K   A    K        +   + K  V  ++ +P   K  L +    P
Sbjct: 751 KSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAP 810

Query: 661 DQD--DDTEIKINIKQE 675
           +++     E+K  +K+E
Sbjct: 811 EKEIPKKEEVKSPVKEE 827


>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
            [Homo sapiens]
          Length = 828

 Score = 98.6 bits (244), Expect = 6e-20
 Identities = 112/517 (21%), Positives = 223/517 (43%), Gaps = 25/517 (4%)

Query: 999  EEEREAEKEAERLMEQASCWEKEEQEILSTRANSRQSPAKVQSKNKYLHSPESRPVTGER 1058
            E+E+E  ++ + L EQ    E+EEQ +        +   K++ + + +   E R    E+
Sbjct: 287  EQEKELREQEKELREQKKLREQEEQ-MQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEK 345

Query: 1059 GQLLELSKESSEEEEE--EEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKP 1116
             Q+ E  ++  ++EE   E+DE   E+EE   E E+  E+EE+ +EEE I+    ++ + 
Sbjct: 346  -QMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREE 404

Query: 1117 QSVAIKRKRPFVLKKKRGRKRRRINSSVTTETISETTEVLNEPFDNSDEERPMPQLEPTC 1176
            +     R++   ++K+      +       + + E  E L E     ++E  + + E   
Sbjct: 405  EETM--REQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKI 462

Query: 1177 EIEVEEDGRKPVLRKAFQHQPGKKRQTEEEEGKDNHCFKNADPCRNNMNDDSSNLKEGSK 1236
              + E  G++  + +  + +  + +  E+EE   +   K  D     M +    L+E  +
Sbjct: 463  RDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQ-EERMWEQDERLREKEE 521

Query: 1237 DNPEPLKCKQVWPKGTKRGLSKWRQNKERKTGFKLNLYTPPETPMEPDEQVTVEEQKETS 1296
               E    K++W +  K    K  Q +E+KT  +       E   E ++++  EE+    
Sbjct: 522  RMREQ---KKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMRE 578

Query: 1297 EGKTSPSPIRIEEEVKETGEALLPQEENRREETCAPVSPNTSPGEKPEDDLIKPEEEEEE 1356
            + +        EE+++E  E +  QEE  +E+            E+ E+D ++ +EE   
Sbjct: 579  QEEKMQEQ---EEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMW 635

Query: 1357 EEEEEEEEEEEEGEEEEGGGNVEKDPDGAKSQEKEEPEISTEKEDSARLDDHEEEEEEDE 1416
            E+EE+ +E+EE+  E+E     E++    + +EK + +    +E   ++   EE+  E E
Sbjct: 636  EQEEKMQEQEEKMWEQEEKMR-EQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQE 694

Query: 1417 EPSHNEDHDADDEDDSHMESAEV--------EKEELPRESFKEVLENQETFLDLNVQPGH 1468
            E    ++     +++      E         EKEE  R+  +++ E      +   +P  
Sbjct: 695  EKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQERLPEHEERCSEPCL 754

Query: 1469 SNPEVLMDCGVDLTASCNSEPKELA-GDPEAVPESDE 1504
               +VL  C +  T S      E   G P+  P + E
Sbjct: 755  PPSKVL--CNMSHTGSVEPAGGEAGEGSPQDNPTAQE 789



 Score = 94.4 bits (233), Expect = 1e-18
 Identities = 111/523 (21%), Positives = 224/523 (42%), Gaps = 53/523 (10%)

Query: 960  REKLILSHMEKLKTCSRANELDPDSLRWTPILISNAAVSEEEREAEKEAERLMEQASCWE 1019
            +EKL L+  EK +      EL    L     L+     +  + E  ++ E L EQ     
Sbjct: 193  QEKLRLAESEKSEIQLNVKELKR-KLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIR 251

Query: 1020 KEEQEILSTRANSRQSPAKVQSKNKYLHSPESRPVTGERGQLLELSKESSEEEEEEEDEE 1079
            K+E+++       R+   K++ + + +   E R    E+ +L E  KE  E+++  E EE
Sbjct: 252  KQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEK-ELREQEKELREQKKLREQEE 310

Query: 1080 EEEEEEEEEEDEEEEEEEEEEE---EEENIQSSPPRLTKP-QSVAIKRKRPFVLKKKRGR 1135
            + +E+EE+  ++EE+  E+EE+   +EE +     ++ +  Q +  + +R +   ++   
Sbjct: 311  QMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLRE 370

Query: 1136 KRRRINSSVTTETISETTEVLNEPFDNSDEERPMPQLEPTCEIEVEEDGRKPVLRKAFQH 1195
            K  R+      E + E  E + E     + E+ M + E T   + E+           Q 
Sbjct: 371  KEERMREQ---EKMWEQEEKMQEEERIREREKKMREEEETMREQEEK----------MQK 417

Query: 1196 QPGKKRQTEEEEGKDNHCFKNADPC--RNNMNDDSSNLKEGSKDNPEPLKCKQVWPKGTK 1253
            Q     + EE+E +     +  +    +  M +    + E  +   +    +++W +  K
Sbjct: 418  QEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQ---EEMWGQEKK 474

Query: 1254 RGLSKWRQNKERKTGFKL------------NLYTPPETPMEPDEQVTVEEQKETSEGKT- 1300
                 WRQ K R+   ++             ++   E   E DE++  +E++   + K  
Sbjct: 475  M----WRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMW 530

Query: 1301 -SPSPIRIEEEVKETGEALLPQEENRREETCAPVSPNTSPGEKP-----EDDLIKPEEEE 1354
                 +R E++ +E  +    QEE  REE            E+      E+ + + EE+ 
Sbjct: 531  QQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKM 590

Query: 1355 EEEEEEEEEEEEEEGEEEEGGGNVEKDPDGAKSQEKEEPEISTEKEDSARLDDHEEEEEE 1414
             E+EE+  E+EE+  E+EE     E+     K  E+EE +   E+E+    +  E+ +E+
Sbjct: 591  REQEEKMWEQEEKMQEQEEKMWEQEE-----KMWEQEEEDKMQEQEE-MMWEQEEKMQEQ 644

Query: 1415 DEEPSHNEDHDADDEDDSHMESAEVEKEELPRESFKEVLENQE 1457
            +E+    E+   + E+    +  +++ +E      +E ++ QE
Sbjct: 645  EEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQE 687



 Score = 58.2 bits (139), Expect = 8e-08
 Identities = 38/181 (20%), Positives = 84/181 (46%)

Query: 958  IRREKLILSHMEKLKTCSRANELDPDSLRWTPILISNAAVSEEEREAEKEAERLMEQASC 1017
            +R +K +    EK++   +  E +  +      +     + E E++  +E E + EQ   
Sbjct: 523  MREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEK 582

Query: 1018 WEKEEQEILSTRANSRQSPAKVQSKNKYLHSPESRPVTGERGQLLELSKESSEEEEEEED 1077
             +++E+++        +   K+Q + + +   E +    E    ++  +E   E+EE+  
Sbjct: 583  MQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQ 642

Query: 1078 EEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQSVAIKRKRPFVLKKKRGRKR 1137
            E+EE+  E+EE+  E+EE+  E+EE+   Q    R  + +    + K     +K RG++ 
Sbjct: 643  EQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEE 702

Query: 1138 R 1138
            +
Sbjct: 703  K 703



 Score = 49.7 bits (117), Expect = 3e-05
 Identities = 48/237 (20%), Positives = 103/237 (43%), Gaps = 19/237 (8%)

Query: 1288 TVEEQ--KETSEGKTSPSPIRIEEEVKETGEALLPQEENRREETCAPVSPNTSPGEKPED 1345
            T++E+  ++  E +     IR +EE     E  L ++E +  E    +        + E 
Sbjct: 231  TLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEK 290

Query: 1346 DLIKPEEEEEEE----EEEEEEEEEEEGEEEEGGGNVEKDPDGAKSQEKEEPEISTEKED 1401
            +L + E+E  E+    E+EE+ +E+EE   E+     E++    + +E+   +    +E 
Sbjct: 291  ELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQ 350

Query: 1402 SARLDDHEEEEEEDEEPSHNEDHDADDEDDSHMESAEVEKEELPRESFKEVLENQETFLD 1461
              ++ D EE   E +E    ++    +++    +  ++++EE  RE  K++ E +ET  +
Sbjct: 351  EQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMRE 410

Query: 1462 LNVQPGHSNPEVLMDCGVDLTASCNSEPKELAGDPEAVPESDEEPPPGEQAQKQDQK 1518
               +       +              E +E     + +PE  E+    E+ Q+Q++K
Sbjct: 411  QEEKMQKQEENMW-------------EQEEKEWQQQRLPEQKEKLWEQEKMQEQEEK 454



 Score = 41.2 bits (95), Expect = 0.011
 Identities = 24/107 (22%), Positives = 50/107 (46%)

Query: 997  VSEEEREAEKEAERLMEQASCWEKEEQEILSTRANSRQSPAKVQSKNKYLHSPESRPVTG 1056
            + E+E +  ++ E++ EQ     ++E+++       R+   K+Q + + +   E +    
Sbjct: 641  MQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQ 700

Query: 1057 ERGQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEE 1103
            E     +  K   +EE+    EE  E+EE   + +E+ +E   E EE
Sbjct: 701  EEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQERLPEHEE 747


>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
            sapiens]
          Length = 1152

 Score = 95.9 bits (237), Expect = 4e-19
 Identities = 123/526 (23%), Positives = 205/526 (38%), Gaps = 27/526 (5%)

Query: 1070 EEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQSVAIKRKRPFVL 1129
            E   +EE E  EE+E  E+      EE+E E  EEN++    R  K + ++        +
Sbjct: 577  EAFSDEEVEIPEEKEGAEDSKGNGIEEQEVEANEENVKVHGGRKEKTEILSDDLTDKAEV 636

Query: 1130 KKKRGRKRRRINSSVTTETISETTEVLNEPFDNSDEERPMPQLEP-TCEIEVEEDGRKPV 1188
             + + +                  E  +      DEER   + +    E+E   +G K +
Sbjct: 637  SEGKAKSVGEAEDGPEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGRGEMERPGEGEKEL 696

Query: 1189 LRKAFQHQPGKKRQTEEEEGKDNHCFKNADPCRNNMNDDSSNLKEGSKDNPEPLKCKQVW 1248
              K    +  KKR  EE+E K+       +  +           EG ++  +  + ++  
Sbjct: 697  AEK----EEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKE 752

Query: 1249 PKGTKRGLSK---WRQNKERKTGFKLNLYTPPETPMEPDEQVTVEEQKETSEGKTSPSPI 1305
             +G + G  +     + KE     K       E   E  +Q   EE++    G+      
Sbjct: 753  GEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGG 812

Query: 1306 RIEE-EVKE-TGEALLPQEENRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEE 1363
             +E  EV+E  GE    +EE   EE           GE+ E +    EE EE E EEE E
Sbjct: 813  EVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGE 872

Query: 1364 EEEEEGEEEEGGGNVEKDPDGAKSQEKEEPEISTEKEDSARLDDHEEEEEEDEEPSHNED 1423
            E E EGEEEEG G  E++ +G   +E+ E E   E E     ++ E + EE+ E    E 
Sbjct: 873  EGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEG 932

Query: 1424 HDADDEDDSHMESAEVEKEELPRESFKEVLENQETFLDLNVQPGHSNPEVLMDCGVDLTA 1483
             + + E +      E E+EE   E  +E  E +        + G    E     G +   
Sbjct: 933  EEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGE------GEEEGEGEGEEGEGEGEEEEG 986

Query: 1484 SCNSEPKELAGDPEAVPESD-EEPPPGEQAQKQDQKNSKEVDTEFKEGNPATMEIDSETV 1542
                E +E  G+ E   E + EE   GE  ++++ +   EV+ E  EG     E + E  
Sbjct: 987  EGEGEEEE--GEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGE 1044

Query: 1543 QAVQS--------LTQESSEQDDTFQDCAETQEACRSLQNYTRADQ 1580
            +  +           +E  E++  +Q+  E +   +  + Y +  +
Sbjct: 1045 EREKEGEGEENRRNREEEEEEEGKYQETGEEENERQDGEEYKKVSK 1090



 Score = 90.1 bits (222), Expect = 2e-17
 Identities = 121/462 (26%), Positives = 181/462 (39%), Gaps = 53/462 (11%)

Query: 999  EEEREAEKEAER-LMEQASCWEKEEQEILSTRANSRQSPAKVQSKNKYLHSPESRPVTGE 1057
            EE  + EK+  R  ME+    EKE  E        R    + Q + +  H  E      E
Sbjct: 672  EEREKGEKDKGRGEMERPGEGEKELAE--KEEWKKRDGEEQEQKEREQGHQKERNQEMEE 729

Query: 1058 RGQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQ 1117
             G+     +E  E EEEE D EEEEE+E E ++E E EE E E E+E  +          
Sbjct: 730  GGE-----EEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGE---------- 774

Query: 1118 SVAIKRKRPFVLKKKRGRKRRRINSSVTTETISETTEVLNEPFDNSDEERPMPQLEPTCE 1177
                 RK+    +++ G++ +        E   E TE   E  +   E       E   E
Sbjct: 775  -----RKK----EERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGE 825

Query: 1178 IEVEEDGRKPVLRKAFQHQPGKKRQTEEEEGKDNHCFKNAD-PCRNNMNDDSSNLKEGSK 1236
             E EE+  +    +    +   + + EE EGK     +  +        +     +EG  
Sbjct: 826  REEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEG 885

Query: 1237 DNPEPLKCKQVWPKGTKRGLSKWRQNKERKTGFKLNLYTPPETPMEPDEQVTVEE----- 1291
            +  E  + +    +G   G  +     E + G         E   E +E+    E     
Sbjct: 886  EGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGE 945

Query: 1292 -QKETSEGKTSPSPIRIEEEVKETGEALLPQEENRREETCAPVSPNTSPGEKPEDDLIKP 1350
             + E  EG+        E E +E GE    + E   EE           GE+ E +    
Sbjct: 946  GEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEE-----EEGEGEGEEEEGE---- 996

Query: 1351 EEEEEEEEEEEEEEEEEEGEEEEGGGNVEKDPDGAKSQEKEEPEISTEKEDSARLDDHEE 1410
            EE EEE E EEE E E E EEE   G VE + +G      EE E   E+E+     +  E
Sbjct: 997  EEGEEEGEGEEEGEGEGEEEEE---GEVEGEVEG------EEGEGEGEEEEGEEEGEERE 1047

Query: 1411 EEEEDEEPSHNEDHDADDEDDSHMESAEVEKEELPRESFKEV 1452
            +E E EE   N + + ++E+  + E+ E E E    E +K+V
Sbjct: 1048 KEGEGEENRRNREEE-EEEEGKYQETGEEENERQDGEEYKKV 1088



 Score = 68.2 bits (165), Expect = 8e-11
 Identities = 102/429 (23%), Positives = 151/429 (35%), Gaps = 75/429 (17%)

Query: 1000 EEREAEKEAERLMEQASCWEKEEQEILSTRANSRQSPAKVQSKNKYLHSPESRPVTGERG 1059
            EE E ++E E   E     E E +E+   R        K +   K     E     G++G
Sbjct: 739  EEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEE----GDQG 794

Query: 1060 QLLELSKESSEEEEEE--------------EDEEEEEEEEEEEEDEEEEEEEEEEEEEEN 1105
            +  E   E   EE+EE              E EEEEEE E EEE+ E EEEE E EEEE 
Sbjct: 795  EGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEG 854

Query: 1106 IQSSPPRLTKPQSVAIKRKRPFVLKKKRGRKRRRINSSVTTETISETTEVLNEPFDNSDE 1165
                                     ++ G +          E   E  E   E  +  + 
Sbjct: 855  EGKG---------------------EEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEG 893

Query: 1166 ERPMPQLEPTCEIEVEEDGRKPVLRKAFQHQPGKKRQTEEEEGKDNHCFKNADPCRNNMN 1225
            E    + E   E E E +G         + +   K + E EEG+                
Sbjct: 894  EGEEEEGEGEGEEEGEGEGE--------EEEGEGKGEEEGEEGEGE-------------G 932

Query: 1226 DDSSNLKEGSKDNPEPLKCKQVWPKGTKRGLSKWRQNKERKTGFKLNLYTPPETPMEPDE 1285
            ++     EG     E  + +  W    + G  +  +  E +           E   E +E
Sbjct: 933  EEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEE 992

Query: 1286 QVTVEEQKETSEGKTSPSPIRIEEEVKETGEALLPQEENRREETCAPVSPNTSPGEKPED 1345
            +   EE +E  EG         EEE +  GE      E    E    V      GE  E+
Sbjct: 993  EEGEEEGEEEGEG---------EEEGEGEGE------EEEEGEVEGEVEGEEGEGEGEEE 1037

Query: 1346 DLIKPEEEEEEEEEEEEEEEEEEGEEEEGGGNVEKDPDGAKSQEKEEPEISTEKEDSARL 1405
            +  +  EE E+E E EE     E EEEE G   E   +  + Q+ EE +  ++ + S + 
Sbjct: 1038 EGEEEGEEREKEGEGEENRRNREEEEEEEGKYQETGEEENERQDGEEYKKVSKIKGSVKY 1097

Query: 1406 DDHEEEEEE 1414
              H+  +++
Sbjct: 1098 GKHKTYQKK 1106



 Score = 37.4 bits (85), Expect = 0.15
 Identities = 35/125 (28%), Positives = 52/125 (41%), Gaps = 27/125 (21%)

Query: 999  EEEREAEKEAERLMEQASCWEKEEQEILSTRANSRQSPAKVQSKNKYLHSPESRPVTGER 1058
            EEE E E E E   E+    E+ E E         +   +V+ +           V GE 
Sbjct: 983  EEEGEGEGEEEEGEEEGE--EEGEGEEEGEGEGEEEEEGEVEGE-----------VEGEE 1029

Query: 1059 GQLLELSKESSEEEEE--------------EEDEEEEEEEEEEEEDEEEEEEEEEEEEEE 1104
            G+     +E  EE EE              EE+EEEE + +E  E+E E ++ EE ++  
Sbjct: 1030 GEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQETGEEENERQDGEEYKKVS 1089

Query: 1105 NIQSS 1109
             I+ S
Sbjct: 1090 KIKGS 1094



 Score = 35.0 bits (79), Expect = 0.76
 Identities = 29/121 (23%), Positives = 54/121 (44%), Gaps = 6/121 (4%)

Query: 999  EEEREAEKEAERLMEQASCWEKEEQEILSTRANSRQSPAKVQSKNKYLHSPESRPVTGER 1058
            E E E E+E E   E     E+EE+  +       +   + + +       E R   GE 
Sbjct: 994  EGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGE-EEGEEREKEGEG 1052

Query: 1059 GQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQS 1118
             +        + EEEEEE+ + +E  EEE E ++ EE ++  + + +++    +  + +S
Sbjct: 1053 EE-----NRRNREEEEEEEGKYQETGEEENERQDGEEYKKVSKIKGSVKYGKHKTYQKKS 1107

Query: 1119 V 1119
            V
Sbjct: 1108 V 1108


>gi|148746195 trichohyalin [Homo sapiens]
          Length = 1943

 Score = 93.6 bits (231), Expect = 2e-18
 Identities = 148/671 (22%), Positives = 266/671 (39%), Gaps = 82/671 (12%)

Query: 959  RREKLILSHMEK-LKTCSRANELDPDSLRWTPILISNAAVSEEEREAEKEAERLMEQASC 1017
            RRE+L+    EK L+   R   L  +       L+       ++R   ++ ERL ++   
Sbjct: 545  RREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKR 604

Query: 1018 WEKE--EQEILSTRANSRQSPAKVQSKN--KYLHSPESRPVTGERGQLLELSKESSEEEE 1073
             E E  EQE    +   R+ P + + +   K     E R     R Q     +    EEE
Sbjct: 605  EEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEE 664

Query: 1074 EEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPR---LTKPQSVAIKRKRPFVLK 1130
            EE  E+  + E EEE  E+E  EEE+E+  E I+S  P+     + ++ A + K     +
Sbjct: 665  EERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPR 724

Query: 1131 KKRGRKRRRINSSVTTETISETTEVLNEPFDNSDEERPMP-------QLEPTCEIEVEED 1183
            K+ G++RR+          SE      E      +E           Q E   E   +  
Sbjct: 725  KQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRL 784

Query: 1184 GRKPVLR-------KAFQHQPGKKRQTEEEEGKDNHCFKNADP-------------CRNN 1223
              +P LR       +A + Q  ++R   EEE K+    +  +               R  
Sbjct: 785  SARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRE 844

Query: 1224 MNDDSSNLKEGSKDNPEPLKCKQVWPKGTKRGLSKWR-QNKERKTGFKLNLYTPP----- 1277
                    ++G +++ E  + ++      +R   KWR Q +E +   +  LY  P     
Sbjct: 845  RAQQLQEEEDGLQEDQERRRSQE------QRRDQKWRWQLEEERKRRRHTLYAKPALQEQ 898

Query: 1278 ----ETPMEPDEQVTVEEQKETSEGKTSPSPIRIEEEVKETGEALLPQE-ENRREETCAP 1332
                +  ++ +E+    E++E    +      R EE++++  E LL +E E RR +    
Sbjct: 899  LRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERER 958

Query: 1333 VSPNTSPGEKPEDDLI--KPEEEEEEEEEEEEEEEEEEGEEEEGGGNVEKDPDGAKSQEK 1390
                    ++ E+ L+  +PE+   +E E++  EEEE  +EEE     E++    +  E+
Sbjct: 959  QYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWER 1018

Query: 1391 ----------EEPEISTEKEDSARLDDHEEEEEEDEEPSHNEDHDADDEDDSHMESAEVE 1440
                      EE ++  E+ +  RL + E +  E+EE    E+    +E ++        
Sbjct: 1019 QYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETR------R 1072

Query: 1441 KEELPRESFKEVLENQETFLDLNVQPGHSNPEVLMDCGVDLTASCNSEPKELAGDPEAVP 1500
            ++EL R+  KE    QE    L  +P     +       +    C  E +EL  + E + 
Sbjct: 1073 RQELERQYRKEEELQQEEEQLLREEPEKRRRQ-------ERERQCREE-EELQQEEEQLL 1124

Query: 1501 ESDEEPPPGEQAQKQDQKNSKEVDTEFKEGNPATMEIDSETVQAVQSLTQESSE-QDDTF 1559
              + E     + Q+ +++  +E + + +E      E +    Q ++   +E  E Q +  
Sbjct: 1125 REEREK---RRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEE 1181

Query: 1560 QDCAETQEACR 1570
            Q   E QE  R
Sbjct: 1182 QLLREEQEKRR 1192



 Score = 92.8 bits (229), Expect = 3e-18
 Identities = 123/599 (20%), Positives = 243/599 (40%), Gaps = 55/599 (9%)

Query: 999  EEEREAEKEAERLMEQASCWEKEEQEILSTRANSRQSPAKVQSKNKYLHSPESRPVTGER 1058
            + E ++E+  +RL  +    E+ E+++   RA  RQ     Q + ++L  PE       R
Sbjct: 772  QAEEKSERGRQRLSARPPLREQRERQL---RAEERQ-----QREQRFL--PEEEEKEQRR 821

Query: 1059 GQLLELSKESS--EEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKP 1116
             Q  E  KE    EEEE+ +  E  ++ +EEE+  +E++E    +E+   Q    +L + 
Sbjct: 822  RQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEE 881

Query: 1117 QSVAIKRKRPFVLKKKRGRKRRRINSSVTTETISETTEVLNEPFDNSDEERPMPQLEPTC 1176
            +    KR+R  +  K   +++ R    +  E   E      E     ++ER   + E   
Sbjct: 882  R----KRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQ 937

Query: 1177 EIEV----EEDGRKPVLRKAFQHQPGKKRQTEEEEGKDNHCFKNADPCRNNMNDDSSNLK 1232
            + E     EE  ++    +  Q++  KK Q +EE+       K     R     +   L+
Sbjct: 938  QEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQ 997

Query: 1233 EGSKD---NPEPLKCKQVWPKGTKRG-------LSKWRQNKERKTGFKLNLYTPPETPME 1282
            +  +         + +Q W +  ++            R+ +E++   +       E  ++
Sbjct: 998  QEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQ 1057

Query: 1283 PDEQVTVEEQKETSEGKTSPSPIRIEEEVKETGEALLPQEENRREETCAPVSPNTSPGEK 1342
             +E+  + E++ET   +      R EEE+++  E LL +E  +R               +
Sbjct: 1058 QEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRR--------------R 1103

Query: 1343 PEDDLIKPEEEEEEEEEEEEEEEEEEGEEEEGGGNVEKDPDGAKSQEKEEPEISTEKEDS 1402
             E +    EEEE ++EEE+   EE E    +    +E+     +  ++EE ++  E+ + 
Sbjct: 1104 QERERQCREEEELQQEEEQLLREEREKRRRQ---ELERQYREEEEVQQEEEQLLREEPEK 1160

Query: 1403 ARLDDHEEEEEEDEEPSHNEDHDADDEDDSHMESAE---VEKEELPRESFKEVLENQETF 1459
             R  + E +  E+EE    E+    +E +   +  E    E+EEL R+  K+   +++  
Sbjct: 1161 RRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQR 1220

Query: 1460 LDLNVQPGHSNPEVLMDCGVDLTASCNSEPKELAGDP--EAVPESDEEPPPGEQAQK--- 1514
             DL  Q        + D  V      N + ++L      +   + D +   GEQ ++   
Sbjct: 1221 SDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDRE 1280

Query: 1515 QDQKNSKEVDTEFKEGNPATMEIDSETVQAVQSLTQESSEQDDTFQDCAETQEACRSLQ 1573
            Q+++  ++ D  F E      E   E  +  +   +E     +  ++    QE  R  +
Sbjct: 1281 QERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFR 1339



 Score = 89.7 bits (221), Expect = 3e-17
 Identities = 101/459 (22%), Positives = 194/459 (42%), Gaps = 38/459 (8%)

Query: 1000 EEREAEKEAERLMEQASCWEKEEQEILSTRANSRQSPAKVQSKNKYLHSPESRPVTGERG 1059
            E +E E++  +L  Q    E++E+E    R    Q   + Q + +     E R     R 
Sbjct: 270  ELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERRE 329

Query: 1060 QLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQSV 1119
            Q  E  ++    E+EE  E++   E+EEE  E++   E+EEE  E       +L + Q +
Sbjct: 330  QQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQL 389

Query: 1120 AIKRKRPFVLKKKRGRKRRRINSSVTTETISETTEVLNEPFDNSDEERPMPQLEPTCEIE 1179
              +++     + +R ++ RR    +  E      + L    +    E+   Q      ++
Sbjct: 390  RREQQLRREQQLRREQQLRR-EQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLK 448

Query: 1180 VEEDGRKPVLRK---AFQHQPGKKRQ----TEEEEGKDNHCFKNADPCRNNMNDDSSNLK 1232
             E++ R+  L++     +H+  +++Q     +EEE ++       +  R         L+
Sbjct: 449  REQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLR 508

Query: 1233 EGSKDNPEP-LKCKQVWPKGTKRGLSKWRQNKERKTGFKLNLYTPPETPMEPDEQVTVEE 1291
               ++  E  LK ++   +  +R  S+ +  +E++               E  EQ+   E
Sbjct: 509  REQEERREQRLKRQEEEERLQQRLRSEQQLRREQE---------------ERREQLLKRE 553

Query: 1292 QKETSEGKTSPSPIRIEEEVKETGEALLPQEENRREETCAPVSPNTSPGEKPEDDLIKPE 1351
            +++  E +      R++ E +E  + LL +EE RR++            E+ E  L + E
Sbjct: 554  EEKRLEQERREQ--RLKREQEERRDQLLKREEERRQQRL-----KREQEERLEQRLKREE 606

Query: 1352 EEEEEEEEEEEEEEEEEGEEEEGGGNVEKDPDGAKSQEKEEPEISTEKEDSARLDDHEEE 1411
             E  E+EE  E+  + E  EEE    + K  +    +E+ + ++  E+++        EE
Sbjct: 607  VERLEQEERREQRLKREEPEEERRQQLLKSEE---QEERRQQQLRREQQERREQRLKREE 663

Query: 1412 EEEDEEPSHNEDHDADDEDDSHMESAEVEKEELPRESFK 1450
            EEE  E     +H   +E+    E AE E++E  RE  K
Sbjct: 664  EEERLEQRLKREH---EEERREQELAE-EEQEQARERIK 698



 Score = 84.3 bits (207), Expect = 1e-15
 Identities = 108/511 (21%), Positives = 212/511 (41%), Gaps = 40/511 (7%)

Query: 969  EKLKTCS--RANEL-DPDSLRWTPILISNAAVSEEEREAEKEAERLMEQASCWEKEEQEI 1025
            E+L++C      E  D + LR   +L       EE+++  +E +  + Q    E+EE+E 
Sbjct: 191  EQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQ----EEEEKEW 246

Query: 1026 LSTRANSRQSPAKVQSKNKYLHSPESRPVTGERGQLL-----ELSKESSEEEEEE----- 1075
                   R+   K+Q +         R +  E  QL      EL +E  EEE+++     
Sbjct: 247  RKRETVLRKEEEKLQEEEPQ----RQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRR 302

Query: 1076 --------EDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQSVAIKRKRPF 1127
                    E+E  E++EE  E+ E  E++EE  E++   +    R  + +    + +R  
Sbjct: 303  EQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQ 362

Query: 1128 VLKKKRGRKRRRINSSVTTETISETTEVLNEPFDNSDEERPMPQLEPTCEIEVEED-GRK 1186
             L++++  +RR        +   E      +      + R   QL    ++  E+   R+
Sbjct: 363  QLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRRE 422

Query: 1187 PVLRKAFQHQPGKKRQTEEEEGKDNHCFKNADPCRNNMNDDSSNLKEGSKDNPEPLKCKQ 1246
              LR+  + +  +  Q  E+E ++    +  +  R+ +  +    +   +   + LK  Q
Sbjct: 423  QQLRR--EQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQ 480

Query: 1247 VWPKGTKRGLSKWRQNKERKTGFKLNLYTPPETPMEPDEQVTVEEQKETSEGKTSPSPIR 1306
               +  +    +  + +E++   +  L    E   E  EQ    +++E    +   S  +
Sbjct: 481  EEERRERWLKLEEEERREQQERREQQLRREQE---ERREQRLKRQEEEERLQQRLRSEQQ 537

Query: 1307 IEEEVKETGEALLPQEENRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEE-EEEEEEE 1365
            +  E +E  E LL +EE +R E            E+  D L+K EEE  ++  + E+EE 
Sbjct: 538  LRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEER 597

Query: 1366 EEEGEEEEGGGNVEKDPDGAKSQEKEEPEISTEKEDSARLDDHEEEEEEDEEPSHNEDHD 1425
             E+  + E    +E++    +  ++EEP    E+E   +L   EE+EE  ++    E  +
Sbjct: 598  LEQRLKREEVERLEQEERREQRLKREEP----EEERRQQLLKSEEQEERRQQQLRREQQE 653

Query: 1426 ADDEDDSHMESAEVEKEELPRESFKEVLENQ 1456
              ++     E  E  ++ L RE  +E  E +
Sbjct: 654  RREQRLKREEEEERLEQRLKREHEEERREQE 684



 Score = 81.6 bits (200), Expect = 7e-15
 Identities = 116/641 (18%), Positives = 247/641 (38%), Gaps = 39/641 (6%)

Query: 992  ISNAAVSEEEREAEKEAERLMEQASCWEKEEQEILSTRANSRQSPA-----KVQSKNKYL 1046
            +  A   +EE+ A  + +  + Q    E++++          + P      K Q + + L
Sbjct: 89   LGQATGLDEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQEREL 148

Query: 1047 HSPESRPVTGERGQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENI 1106
               E +    ER     L +   +  +EE   + +E +E EE   EEE+ +  +  E   
Sbjct: 149  AEGEEQSEKQER-----LEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEE 203

Query: 1107 QSSPPRLTKPQSVAIKRKRPFVLKKKRGRKRRRINSSVTTETISETTEVLNEPFDNSDEE 1166
                 +L + + + ++RK     +++R  ++ R+      +   +   VL +  +   EE
Sbjct: 204  FPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEE 263

Query: 1167 RPMPQLEPTCEIEVEEDGRKPVLRKAFQHQPGKK---------RQTEEEEGKDNHCFKNA 1217
             P  Q E   E E      +  LR+  Q +  ++         R+ +EEE ++    +  
Sbjct: 264  EPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERRE 323

Query: 1218 DPCRNNMNDD--SSNLKEGSKDNPEPLKCKQVWPKGTKRGLSKWRQNKERKTGFKLNLYT 1275
               R    ++     L+   ++  E    ++   +  ++ L + ++ + R+   +     
Sbjct: 324  QQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQL 383

Query: 1276 PPETPMEPDEQVTVEEQKETSEGKTSPSPIRIEEEVKETGEALLPQEENRREETCAPVSP 1335
              E  +  ++Q+  E+Q    +       +R E++++   +    QEE R E+       
Sbjct: 384  RREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERR 443

Query: 1336 NTSPGEKPED--DLIKPEEEEEEEEEEEEEEEEEEGEEEEGGGNVEK--DPDGAKSQEKE 1391
                  + E+  D +K EEE E  E+E  +++ +  +EEE      K  + +  + QE+ 
Sbjct: 444  EQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERR 503

Query: 1392 EPEISTEKED--SARLDDHEEEEE-----EDEEPSHNEDHDADDEDDSHMESAEVEKEEL 1444
            E ++  E+E+    RL   EEEE        E+    E  +  ++     E   +E+E  
Sbjct: 504  EQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERR 563

Query: 1445 PRESFKEVLENQETFLDLNVQPGHSNPEVLMDCGVDLTASCNSEPKELAGDPEAVPESDE 1504
             +   +E  E ++  L    +      +   +  ++       E + L  +         
Sbjct: 564  EQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLK-REEVERLEQEERREQRLKR 622

Query: 1505 EPPPGEQAQ------KQDQKNSKEVDTEFKEGNPATMEIDSETVQAVQSLTQESSEQDDT 1558
            E P  E+ Q      +Q+++  +++  E +E     ++ + E  +  Q L +E  E+   
Sbjct: 623  EEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERRE 682

Query: 1559 FQDCAETQEACRSLQNYTRADQSPQIATTLDDCQQSDHSSP 1599
             +   E QE  R            Q+ +  D  Q   +S P
Sbjct: 683  QELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRP 723



 Score = 79.3 bits (194), Expect = 4e-14
 Identities = 99/460 (21%), Positives = 188/460 (40%), Gaps = 60/460 (13%)

Query: 1000 EEREAEKEAERLMEQASCWEKEEQEILSTRANSRQSPAKVQSKNKYLHSPESRPVTGERG 1059
            EE E ++E E+L+ +    E+E +         R+     Q + + L     +    ER 
Sbjct: 1052 EEEELQQEEEQLLGE----ERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERE 1107

Query: 1060 QLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQSV 1119
            +     +E  +EEE+   EE E+   +E E +  EEEE ++EEE+ ++  P         
Sbjct: 1108 RQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPE-------- 1159

Query: 1120 AIKRKRPFVLKKKRGRKRRRINSSVTTETISETTEVLNEPFDNSDEERPMPQLEPTCEIE 1179
              KR+R  + ++ R  +          E   E  ++L E  +   +ER     E   E E
Sbjct: 1160 --KRRRQELERQYREEE----------ELQQEEEQLLREEQEKRRQERERQYRE---EEE 1204

Query: 1180 VEEDGRKPVLRKAFQHQPGKKRQTEEEEGKDNHCFKNADPCRNNMNDDSSNLKEGS-KDN 1238
            ++   RK   R   Q +   K Q E E  K+N    N   C+   N+    L++   +D 
Sbjct: 1205 LQRQKRKQRYRDEDQ-RSDLKWQWEPE--KENAVRDNKVYCKGRENEQFRQLEDSQLRDR 1261

Query: 1239 PEPLKCKQVWPKGTKRGLSKWRQNKERKTGFKLNLYTPPETPMEPDEQVTVEEQKETSEG 1298
                  + +  +  +R      + +ER+   + + + P E      EQ+  EEQKE    
Sbjct: 1262 QSQQDLQHLLGEQQERD-----REQERRRWQQRDRHFPEE------EQLEREEQKEAK-- 1308

Query: 1299 KTSPSPIRIEEEVKETGEALLPQEENRREETCAPVSPNTSPGEKPEDDLIKPEEEEE-EE 1357
                   R + + +E  + L  + E +R          T    + E+ L++  EE+    
Sbjct: 1309 -------RRDRKSQEEKQLLREEREEKRRR------QETDRKFREEEQLLQEREEQPLRR 1355

Query: 1358 EEEEEEEEEEEGEEEEGGGNVEKDPDGAKSQEKEEPEISTEKEDSARLDDHEEEEEEDEE 1417
            +E + +  EEE   +E G    ++    + QE+E   +  ++E   R  + E++  +D +
Sbjct: 1356 QERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFL--KEEQQLRCQEREQQLRQDRD 1413

Query: 1418 PSHNEDHDADDEDDSHMESAEVEKEELPRESFKEVLENQE 1457
                E+       +   +  E E++   +E  ++ LE ++
Sbjct: 1414 RKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQ 1453



 Score = 76.6 bits (187), Expect = 2e-13
 Identities = 97/495 (19%), Positives = 196/495 (39%), Gaps = 87/495 (17%)

Query: 979  ELDPDSLRWTPILISNAAVSEEEREAEKEAERLMEQASCWEKEEQEILSTRANSRQSPAK 1038
            +L+ +  R    L +  A+ E+ R+ ++  +   E+    E+E++         R+    
Sbjct: 877  QLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQL 936

Query: 1039 VQSKNKYLHSPESRPVTGERGQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEE 1098
             Q + + L     +    ER +     K+  ++EE+   EE E+   +E E +  EEEE 
Sbjct: 937  QQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEEL 996

Query: 1099 EEEEEENIQSSPPRLTKPQSVAIKRKRPFVLKKKRGRKRRRINSSVTTETISETTEVLNE 1158
            ++EEE+                       +L+++R ++RR+           E      +
Sbjct: 997  QQEEEQ-----------------------LLREEREKRRRQ-----------EWERQYRK 1022

Query: 1159 PFDNSDEERPMPQLEPTCEIEVEEDGRKPVLRKAFQHQPGKKRQTEEEE--GKDNHCFKN 1216
              +   EE  + +         EE  ++ +  +  Q++  ++ Q EEE+  G++    + 
Sbjct: 1023 KDELQQEEEQLLR---------EEREKRRLQERERQYREEEELQQEEEQLLGEERETRRR 1073

Query: 1217 ADPCRNNMNDDSSNLKEGSKDNPEPLKCKQVWPKGTKRGLSKWRQNKERKTGFKLNLYTP 1276
             +  R    ++    +E      EP K              + RQ +ER+          
Sbjct: 1074 QELERQYRKEEELQQEEEQLLREEPEK--------------RRRQERERQ--------CR 1111

Query: 1277 PETPMEPDEQVTVEEQKETSEGKTSPSPIRIEEEVKETGEALLPQE-ENRREETCAPVSP 1335
             E  ++ +E+  + E++E    +      R EEEV++  E LL +E E RR +       
Sbjct: 1112 EEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYR 1171

Query: 1336 NTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGEEEEGGGNVEKDPDGAKSQEKEEPEI 1395
                 ++ E+ L++ E+E+  +E E +  EEEE + ++       +   +  + + EPE 
Sbjct: 1172 EEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEK 1231

Query: 1396 ST------------EKEDSARLDD---HEEEEEEDEEPSHNEDHDADDEDD----SHMES 1436
                          E E   +L+D    + + ++D +    E  + D E +       + 
Sbjct: 1232 ENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDR 1291

Query: 1437 AEVEKEELPRESFKE 1451
               E+E+L RE  KE
Sbjct: 1292 HFPEEEQLEREEQKE 1306



 Score = 70.1 bits (170), Expect = 2e-11
 Identities = 100/561 (17%), Positives = 232/561 (41%), Gaps = 59/561 (10%)

Query: 999  EEEREAEKEAERLMEQASCWEKEEQEILSTRANSRQSPAKVQSKNKYLHSPESRPVTGER 1058
            EE++EA++   +  E+     +E +E    +   +++  K + + + L   E +P+  + 
Sbjct: 1302 EEQKEAKRRDRKSQEEKQLLREEREE----KRRRQETDRKFREEEQLLQEREEQPLRRQE 1357

Query: 1059 GQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQS 1118
                   K   EE   +E   +  EEE+    +E E +  +EE++   Q    +L + + 
Sbjct: 1358 RD----RKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRD 1413

Query: 1119 VAIKRKRPFVLKKKRGRKRRRINSSVTTET-----ISETTEVLNEPFDNSDEERPMPQLE 1173
               + +   + +++R RK R     V  +      + E  ++  E      EE  + Q  
Sbjct: 1414 RKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQ-- 1471

Query: 1174 PTCEIEVEEDGRKPVLRKAFQHQPGKKRQTEEEEGKDNHCFKNADPCRNNMNDDSSNLKE 1233
               E E ++  R+   RK  + +   +RQ  + + ++    ++ +P R  + ++    ++
Sbjct: 1472 ---EREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQE-LRSQEPERKFLEEEQQLHRQ 1527

Query: 1234 GSKDNPEPLKCKQVWPKGTKRGLSKWRQNKERKTGFKLNLYTPPETPMEPDEQVTVEEQK 1293
                       ++   +  +RG  + RQ+++RK       +   E   +  E+  +  Q+
Sbjct: 1528 ---QRQRKFLQEEQQLRRQERGQQR-RQDRDRK-------FREEEQLRQEREEQQLSRQE 1576

Query: 1294 ETSEGKTSPSPIRIEEEVKETGEALLPQEENRREETCAPVSPNTSPGEKPEDDLIKPEEE 1353
               + +     +R +E+ ++  E    +++ RR+E    +        + ++ L++  EE
Sbjct: 1577 RDRKFRLEEQKVRRQEQERKFME---DEQQLRRQEGQQQLRQERDRKFREDEQLLQEREE 1633

Query: 1354 EEEEEEEEEE---EEEEEGEEEEGGGNVEKDPDGAKSQEKEEPEISTEKEDSARLDDHEE 1410
            ++   +E +    EEE +   +E    +  D D  K +E+E+     E++   R +   +
Sbjct: 1634 QQLHRQERDRKFLEEEPQLRRQEREQQLRHDRD-RKFREEEQLLQEGEEQQLRRQERDRK 1692

Query: 1411 EEEEDEEPSHNEDHDADDEDDSHMESAEVEK-----EELPRESFKEVLENQETFLDLNVQ 1465
              EE+++    E      +++  +   E+E+     E+L +E+ +E L  QE +  + ++
Sbjct: 1693 FREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKI-LE 1751

Query: 1466 PGHSNPEVLMDCGVDLTASCNSEPKELAGDPEAVPESDEEPPPGEQAQKQDQKNSKEVDT 1525
                 PE               E ++L          +EE     Q +++ Q  S+E D 
Sbjct: 1752 EEQLRPE--------------REEQQLRRQERDRKFREEEQL--RQEREEQQLRSQESDR 1795

Query: 1526 EFKEGNPATMEIDSETVQAVQ 1546
            +F+E      E + + ++  Q
Sbjct: 1796 KFREEEQLRQEREEQQLRPQQ 1816



 Score = 67.0 bits (162), Expect = 2e-10
 Identities = 100/492 (20%), Positives = 200/492 (40%), Gaps = 43/492 (8%)

Query: 998  SEEERE---AEKEAERLMEQASCWEKEEQEILSTRANS---RQSPAKVQSKNKYLHSPES 1051
            S+EE++    E+E +R  ++     +EE+++L  R      RQ   +   + +  H  + 
Sbjct: 1314 SQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQG 1373

Query: 1052 RPVTGERGQLLELSKESSEEEEEEE--------------DEEEEEEEEEEEEDEEEEEEE 1097
            R    E  +L    +E    +EE++              D +  EEE++    E + +  
Sbjct: 1374 RKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFR 1433

Query: 1098 EEEEEEENIQSSPPRLTKPQSVAIKRKRPF-----VLKKKRGRKRRRINSSVTTETISET 1152
            EEE++    +     L + Q +  +R R F     +L+++  ++  R       + + E 
Sbjct: 1434 EEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHR--QERDRKFLEEE 1491

Query: 1153 TEVLNEPFDNSDEERPMPQLEPTCEIEVEED--GRKPVLRKAFQHQPGKKRQTEEEEGKD 1210
             ++  +  D    E+ +   EP  +   EE    R+   RK  Q +   +RQ   ++ + 
Sbjct: 1492 QQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQ 1551

Query: 1211 NHCFKNADPCRNNMNDDSSNLKEGSKDNPEPLKCKQVWPKGTKRGLSKWRQNKERKTGFK 1270
            +   K  +  +     +   L    +D    L+ ++V  +  +R   +  Q   R+ G +
Sbjct: 1552 DRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEG-Q 1610

Query: 1271 LNLYTPPETPMEPDEQVTVEEQKETSEGKTSPSPIRIEEEVKETGEALLPQEENRREETC 1330
              L    +     DEQ+ ++E++E    +       +EEE +   +    Q  + R+   
Sbjct: 1611 QQLRQERDRKFREDEQL-LQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKF 1669

Query: 1331 APVSPNTSPGEKPEDDLIKPEEEEEEEEEEEE---EEEEEEGEEEEGGGNVEKDPDGAKS 1387
                     GE  E  L + E + +  EEE++   +E E +  +EE    + +     K 
Sbjct: 1670 REEEQLLQEGE--EQQLRRQERDRKFREEEQQLRRQERERKFLQEE--QQLRRQELERKF 1725

Query: 1388 QEKEEPEISTEKEDSARLDDHEE-EEEEDEEPSHNEDHDADDEDDSHMESAEVEKEELPR 1446
            +E+E+    TE+E   R + + +  EEE   P   E      E D        E+E+L +
Sbjct: 1726 REEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFR----EEEQLRQ 1781

Query: 1447 ESFKEVLENQET 1458
            E  ++ L +QE+
Sbjct: 1782 EREEQQLRSQES 1793



 Score = 67.0 bits (162), Expect = 2e-10
 Identities = 101/530 (19%), Positives = 204/530 (38%), Gaps = 60/530 (11%)

Query: 960  REKLILSHMEKLKTCSRANELDPD---SLRWTPILISNAAVSEEEREAEKEAERLMEQAS 1016
            RE+  L   ++L+   R  +L  D     R     +S      + RE E++  R   +  
Sbjct: 1388 RERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERK 1447

Query: 1017 CWEKEEQEILSTRANSRQSPAKVQSKNKY-LHSPE-SRPVTGERGQLLELSKESSEEEEE 1074
              E+E+Q         R+    +Q + +  LH  E  R    E  QL    ++    E+E
Sbjct: 1448 FLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQE 1507

Query: 1075 EEDEEEEEEEEEEEED-----------EEEEEEEEEEEEEENIQSSPPRLTKPQSVAIKR 1123
               +E E +  EEE+            +EE++   +E  ++  Q    +  + + +  +R
Sbjct: 1508 LRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQER 1567

Query: 1124 KRPFVLKKKRGRKRRRINSSVTTETISETTEVLNEPFDNSDEERPMPQLEPTCEIEVEED 1183
            +   + +++R RK R     V  +   E      E       +    QL    + +  ED
Sbjct: 1568 EEQQLSRQERDRKFRLEEQKVRRQ---EQERKFMEDEQQLRRQEGQQQLRQERDRKFRED 1624

Query: 1184 G------------RKPVLRKAFQHQPGKKRQTEEEEGKDNHCFKNADPCRNNMNDDSSNL 1231
                         R+   RK  + +P  +RQ  E++ + +   K          ++   L
Sbjct: 1625 EQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRK--------FREEEQLL 1676

Query: 1232 KEGSKDNPEPLKCKQVWPKGTKRGLSKWRQNKERKTGFKLNLYTPPETPMEPDEQVTVEE 1291
            +EG +   + L+ ++   K  +      RQ +ERK       +   E  +   E      
Sbjct: 1677 QEGEE---QQLRRQERDRKFREEEQQLRRQERERK-------FLQEEQQLRRQELERKFR 1726

Query: 1292 QKETSEGKTSPSPIRIEEEVKETGEALLPQEENRREETCAPVSPNTSPGEKPEDDLIKPE 1351
            ++E    +T    +R +E  ++    +L +E+ R E     +       +  E++ ++ E
Sbjct: 1727 EEEQLRQETEQEQLRRQERYRK----ILEEEQLRPEREEQQLRRQERDRKFREEEQLRQE 1782

Query: 1352 EEEEEEEEEEEE----EEEEEGEEEEGGGNVEKDPDGAKSQEKEEPEISTEKEDSARLDD 1407
             EE++   +E +    EEE+  +E E      +  DG    E+E+ ++   +E   RL  
Sbjct: 1783 REEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQL---EEQEQRLRQ 1839

Query: 1408 HEEEEEEDEEPSHNEDHDADDEDDSHMESAEVEKEELPRESFKEVLENQE 1457
              + +   EE    ++    +E +   E  +  ++E  R+  +E +  Q+
Sbjct: 1840 ERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQ 1889



 Score = 49.7 bits (117), Expect = 3e-05
 Identities = 85/430 (19%), Positives = 163/430 (37%), Gaps = 45/430 (10%)

Query: 999  EEEREAEKEAERLMEQASCWEKEEQEILSTRANSR-----QSPAKVQSKNKYLHSPESRP 1053
            E +R+  +E ++L  Q    +  EQE+ S     +     Q   + Q + K+L   E + 
Sbjct: 1482 ERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQE-EQQL 1540

Query: 1054 VTGERGQLLELSKESSEEEEEEEDEEEEEE-------------EEEEEEDEEEEEEEEEE 1100
               ERGQ     ++    EEE+  +E EE+             EE++   +E+E +  E+
Sbjct: 1541 RRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMED 1600

Query: 1101 EEEENIQSSPPRLTKPQSVAIKRKRPFVLKKKRGRKRRRINSSVTTETISETTEVLNEPF 1160
            E++   Q    +L + +    +     + +++  +  R+       E   +      E  
Sbjct: 1601 EQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQ 1660

Query: 1161 DNSDEERPMPQLEPTCEIEVEEDGRKPVLRKAFQHQPGKKRQTEEEEG-----------K 1209
               D +R   + E   +   E+  R+    + F+ +  + R+ E E             +
Sbjct: 1661 LRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQE 1720

Query: 1210 DNHCFKNADPCRNNMNDDSSNLKEGSKDNPEPLKCKQVWPKGTKRGLSKWRQNKERKTGF 1269
                F+  +  R     +    +E  +   + L+ +Q+ P+  ++ L   RQ ++RK   
Sbjct: 1721 LERKFREEEQLRQETEQEQLRRQERYR---KILEEEQLRPEREEQQLR--RQERDRKFRE 1775

Query: 1270 KLNLYTPPETPM----EPDEQVTVEEQ--KETSEGKTSPSP----IRIEEEVKETGEALL 1319
            +  L    E       E D +   EEQ  +E  E +  P       R EEE  +  E   
Sbjct: 1776 EEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQ 1835

Query: 1320 PQEENRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGEEEEGGGNVE 1379
               + R  +  A     T    + E+  +  EEE++  +E E +  EE    ++      
Sbjct: 1836 RLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKEEQRH 1895

Query: 1380 KDPDGAKSQE 1389
            +     KSQE
Sbjct: 1896 RQVGEIKSQE 1905



 Score = 41.6 bits (96), Expect = 0.008
 Identities = 65/373 (17%), Positives = 147/373 (39%), Gaps = 67/373 (17%)

Query: 999  EEEREAEKEAERLMEQASCWEKEEQEILSTRANSRQSPAKVQSKNKYLHS-PESRPVTGE 1057
            E++   ++  ++L ++     +E++++L  R    Q   + +   K+L   P+ R    E
Sbjct: 1601 EQQLRRQEGQQQLRQERDRKFREDEQLLQER--EEQQLHRQERDRKFLEEEPQLRRQERE 1658

Query: 1058 RGQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQ 1117
            +    +  ++  EEE+  ++ EE++   +E + +  EEE++   +E              
Sbjct: 1659 QQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQE-------------- 1704

Query: 1118 SVAIKRKRPFVLKKKRGRKRRRINSSVTTETISETTEVLNEPFDNSDEERPMPQLEPTCE 1177
                 R+R F+ ++++ R++         E + + TE   E     +  R + + E    
Sbjct: 1705 -----RERKFLQEEQQLRRQELERKFREEEQLRQETE--QEQLRRQERYRKILEEEQLRP 1757

Query: 1178 IEVEEDGRKPVLRKAFQHQPGKKRQTEEEEGKDNHCFKNADPCRNNMNDDSSNLKEGSKD 1237
               E+  R+    + F+ +   +++ EE++             R+  +D     +E  + 
Sbjct: 1758 EREEQQLRRQERDRKFREEEQLRQEREEQQ------------LRSQESDRKFREEEQLRQ 1805

Query: 1238 NPEPLKCKQVWPKGTKRGLSKWRQNKERKTGFKLNLYTPPETPMEPDEQVTVEEQKETSE 1297
              E  + +     G  R   +  Q +E++   +           E D Q   EEQ  T  
Sbjct: 1806 EREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLR----------QERDRQYRAEEQFATQ- 1854

Query: 1298 GKTSPSPIRIEEEVKETGEALLPQEENRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEE 1357
                      E+  +E  E    +E+ RR+E             K  ++ I+ +++EE+ 
Sbjct: 1855 ----------EKSRREEQELWQEEEQKRRQER----------ERKLREEHIRRQQKEEQR 1894

Query: 1358 EEEEEEEEEEEGE 1370
              +  E + +EG+
Sbjct: 1895 HRQVGEIKSQEGK 1907



 Score = 40.0 bits (92), Expect = 0.024
 Identities = 29/143 (20%), Positives = 64/143 (44%), Gaps = 2/143 (1%)

Query: 997  VSEEEREAEKEAERLMEQASCWEKEEQEILSTRANSRQSPAKVQSKNKYLHSPESRPVTG 1056
            + EE+   E+E ++L  Q    +  E+E L  R    +   + Q  ++     E      
Sbjct: 1750 LEEEQLRPEREEQQLRRQERDRKFREEEQL--RQEREEQQLRSQESDRKFREEEQLRQER 1807

Query: 1057 ERGQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKP 1116
            E  QL    ++     EEE+ + EE+E+   +E + +   EE+   +E  +     L + 
Sbjct: 1808 EEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQE 1867

Query: 1117 QSVAIKRKRPFVLKKKRGRKRRR 1139
            +    +++R   L+++  R++++
Sbjct: 1868 EEQKRRQERERKLREEHIRRQQK 1890


>gi|84043963 eukaryotic translation initiation factor 5B [Homo
            sapiens]
          Length = 1220

 Score = 90.5 bits (223), Expect = 2e-17
 Identities = 106/455 (23%), Positives = 194/455 (42%), Gaps = 67/455 (14%)

Query: 992  ISNAAVSEEEREAEKEAERLMEQASCWEKEEQEILSTRANSRQSPAKVQSKNKYLHSPES 1051
            ++     ++ERE +K  E   +     EKEE E        +    + +S+ K+      
Sbjct: 228  VAQKKAEKKERERKKRDEEKAKLRKLKEKEELE-----TGKKDQSKQKESQRKFEEETVK 282

Query: 1052 RPVTGERGQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPP 1111
              VT + G ++  S+E +E     ED+ E ++++++++ ++ E+EE+E+E+++       
Sbjct: 283  SKVTVDTG-VIPASEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKG------ 335

Query: 1112 RLTKPQSVAIKRKRPFVLKKKRGRKRRRINSSVTTETISETTEVLNEPFDNSDEERPMPQ 1171
                P    +K  +  + K K   +R++                        +EE  + +
Sbjct: 336  ----PSKATVKAMQEALAKLKEEEERQK-----------------------REEEERIKR 368

Query: 1172 LEPTCEIEVEEDGRKPVLRKAFQHQPGKKRQTEEEEGKDNHCFKNADPCRNNMNDDSSNL 1231
            LE       EE+  +   R+  + +  ++++  ++EGK     K+    R         L
Sbjct: 369  LEELEAKRKEEERLEQEKRERKKQKEKERKERLKKEGK--LLTKSQREARARAEATLKLL 426

Query: 1232 KEGSKDNPEPLKCKQVWPKGTKRGLSKWRQNKERKTGFKLNLYTPPETPMEPDEQVTVEE 1291
            +    + P     K   PK  KR +  +   K +K   +L      E+ ME    V V E
Sbjct: 427  QAQGVEVPS----KDSLPK--KRPI--YEDKKRKKIPQQLESKEVSES-MELCAAVEVME 477

Query: 1292 QKETSEGKTSPSPIRIEEEVKETGEALLPQEENRREETCAPVSPNTSPGEKPEDDLIKPE 1351
            Q    E + +P P+  EEE       L   E    +E    V  N    E      +K  
Sbjct: 478  QG-VPEKEETPPPVEPEEEEDTEDAGLDDWEAMASDEETEKVEGNKVHIE------VKEN 530

Query: 1352 EEEEEEEEEEEEEEEEEGEEEEGGGNVEKDPDGAKSQEKEEPEISTEKEDSARLDDHEEE 1411
             EEEEEEEEEEEE+EE  EEEE  G    + +G++  E++E ++S EK+    LD     
Sbjct: 531  PEEEEEEEEEEEEDEESEEEEEEEG----ESEGSEGDEEDE-KVSDEKDSGKTLD----- 580

Query: 1412 EEEDEEPSHNEDHDADDEDDSHMESAEVEKEELPR 1446
            ++  +E S + ++D+DD+      + +  K  + +
Sbjct: 581  KKPSKEMSSDSEYDSDDDRTKEERAYDKAKRRIEK 615



 Score = 84.0 bits (206), Expect = 1e-15
 Identities = 103/549 (18%), Positives = 242/549 (44%), Gaps = 68/549 (12%)

Query: 1062 LELSKESSEEEEEEEDEEEEEEEEEEEEDEEE--EEEEEEEEEEENIQSSPPRLTKPQSV 1119
            +E +  + E+E ++   ++++E+++++ DE++  +E EE   E + I++    +    + 
Sbjct: 26   IEGAGAAKEQEPQKSKGKKKKEKKKQDFDEDDILKELEELSLEAQGIKADRETVAVKPTE 85

Query: 1120 AIKRKRPFVLKKKRGRKRRRINSSVTTETISETTEVLNEPFDNSDEERPMPQLEPTCEIE 1179
              + +     KKK+G+K ++       ++  +      E  D+  ++   P++E     +
Sbjct: 86   NNEEEFTSKDKKKKGQKGKK-------QSFDDNDSEELEDKDSKSKKTAKPKVEMYSGSD 138

Query: 1180 VEEDGRKPVLRKAFQHQPGKKRQTEEEEGKDNHCFKNADPCRNNMNDDSSNLKEGSKDNP 1239
             ++D  K   +   + Q   K+    EE +DN   K  +  R N + +S +      ++ 
Sbjct: 139  DDDDFNKLPKKAKGKAQKSNKKWDGSEEDEDN-SKKIKERSRINSSGESGD------ESD 191

Query: 1240 EPLKCKQVWPKGTKR--GLSKWRQNKERKTGFKLNLYTPPETPMEPDEQVTVEEQKETSE 1297
            E L+ ++   K  K   G +    N++    FK+      +T  +   +    E+K+  E
Sbjct: 192  EFLQSRKGQKKNQKNKPGPNIESGNEDDDASFKI------KTVAQKKAEKKERERKKRDE 245

Query: 1298 GKTSPSPIRIEEEVKETGEALLPQEENRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEE 1357
             K     ++ +EE+ ETG+    +++++++E+       T   +   D  + P  EE+ E
Sbjct: 246  EKAKLRKLKEKEEL-ETGK----KDQSKQKESQRKFEEETVKSKVTVDTGVIPASEEKAE 300

Query: 1358 -----EEEEEEEEEEEGEEEEGGGNVEKDPDGAKSQEKEEPEISTEKEDSARLDDHEEEE 1412
                 E++ E +++++ ++++ G   EK+ +  K   K   +   E     + ++  ++ 
Sbjct: 301  TPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKR 360

Query: 1413 EEDEEPSHNEDHDADDEDDSHMESAEVEKEELPRESFKEVLENQETFLDLNVQPGHSNPE 1472
            EE+E     E+ +A  +++  +E  + E+++   +  KE L+ +   L  + +   +  E
Sbjct: 361  EEEERIKRLEELEAKRKEEERLEQEKRERKKQKEKERKERLKKEGKLLTKSQREARARAE 420

Query: 1473 ----VLMDCGVDLTASCN-------------------------SEPKELAGDPE----AV 1499
                +L   GV++ +  +                         SE  EL    E     V
Sbjct: 421  ATLKLLQAQGVEVPSKDSLPKKRPIYEDKKRKKIPQQLESKEVSESMELCAAVEVMEQGV 480

Query: 1500 PESDEEPPPGEQAQKQDQKNSKEVDTEFKEGNPATMEIDSETVQ-AVQSLTQESSEQDDT 1558
            PE +E PPP E  +++D +++   D E    +  T +++   V   V+   +E  E+++ 
Sbjct: 481  PEKEETPPPVEPEEEEDTEDAGLDDWEAMASDEETEKVEGNKVHIEVKENPEEEEEEEEE 540

Query: 1559 FQDCAETQE 1567
             ++  E++E
Sbjct: 541  EEEDEESEE 549



 Score = 71.6 bits (174), Expect = 7e-12
 Identities = 110/589 (18%), Positives = 230/589 (39%), Gaps = 117/589 (19%)

Query: 1048 SPESRPVTGERGQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQ 1107
            S E++ +  +R  +     E++EEE   +D++++ ++ +++  ++ + EE E+++ ++ +
Sbjct: 66   SLEAQGIKADRETVAVKPTENNEEEFTSKDKKKKGQKGKKQSFDDNDSEELEDKDSKSKK 125

Query: 1108 SSPPRLTKPQSVAIKRKRPFVLKKKRGRKRRRINSSVTTETISETTEVLNEPFDNSDEER 1167
            ++ P++              + KK +G+ ++                  N+ +D S+E+ 
Sbjct: 126  TAKPKVEMYSGSDDDDDFNKLPKKAKGKAQKS-----------------NKKWDGSEED- 167

Query: 1168 PMPQLEPTCEIEVEEDGRKPVLRKAFQHQPGKKRQTEEEEGKDNHCFKNADPCRNNMNDD 1227
                          ED  K +  ++  +  G     E  +  D          +N  N  
Sbjct: 168  --------------EDNSKKIKERSRINSSG-----ESGDESDEFLQSRKGQKKNQKNKP 208

Query: 1228 SSNLKEGSKDNPEPLKCKQVWPKGTKRGLSKWRQNKERKTGFKLNLYTPPETPMEPDEQV 1287
              N++ G++D+    K K V  K  ++   + ++  E K   +  L    E      +Q 
Sbjct: 209  GPNIESGNEDDDASFKIKTVAQKKAEKKERERKKRDEEKAKLR-KLKEKEELETGKKDQS 267

Query: 1288 TVEEQKETSEGKTSPSPIRIEEEVKETGEALLPQEENRREETCAPVSPNTSPGEKPEDDL 1347
              +E +   E +T  S + ++  V       +P  E + E   A    N    +K +   
Sbjct: 268  KQKESQRKFEEETVKSKVTVDTGV-------IPASEEKAETPTAAEDDNEGDKKKKDKKK 320

Query: 1348 IKPEEEEEEEEEEE------------------EEEEEEEGEEEEGGGNVEKDPDGAKSQE 1389
             K E+EE+E+E+++                  EEEE ++ EEEE    +E+     +++ 
Sbjct: 321  KKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERIKRLEE----LEAKR 376

Query: 1390 KEEPEISTEKEDSARLDDHEEEEEEDEE-----PSHNEDHDADDEDDSHMESAEVE---K 1441
            KEE  +  EK +  +  + E +E   +E      S  E     +     +++  VE   K
Sbjct: 377  KEEERLEQEKRERKKQKEKERKERLKKEGKLLTKSQREARARAEATLKLLQAQGVEVPSK 436

Query: 1442 EELPRE----------------SFKEVLENQETFLDLNVQ----------PGHSNPEV-- 1473
            + LP++                  KEV E+ E    + V           P    PE   
Sbjct: 437  DSLPKKRPIYEDKKRKKIPQQLESKEVSESMELCAAVEVMEQGVPEKEETPPPVEPEEEE 496

Query: 1474 -LMDCGVD--LTASCNSEPKELAGDP------EAVPESDEEPPPGEQAQKQDQKNSKEVD 1524
               D G+D     + + E +++ G+       E   E +EE    E+ ++ +++  +E +
Sbjct: 497  DTEDAGLDDWEAMASDEETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEESEEEEEEEGE 556

Query: 1525 TEFKEGNPATMEIDSE-----TVQAVQSLTQESSEQDDTFQDCAETQEA 1568
            +E  EG+    ++  E     T+    S    S  + D+  D  + + A
Sbjct: 557  SEGSEGDEEDEKVSDEKDSGKTLDKKPSKEMSSDSEYDSDDDRTKEERA 605



 Score = 68.2 bits (165), Expect = 8e-11
 Identities = 93/459 (20%), Positives = 182/459 (39%), Gaps = 62/459 (13%)

Query: 1020 KEEQEILSTRANSRQSPAKVQSKNKYLHSPESRPVTGERGQLLELSKESSEEEEEEEDEE 1079
            KE   I S+  +  +S   +QS+     + +++P              + E   E++D  
Sbjct: 175  KERSRINSSGESGDESDEFLQSRKGQKKNQKNKP------------GPNIESGNEDDDAS 222

Query: 1080 EEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQSVAIKRKRPFVLKKKRGRKRRR 1139
             + +   +++ E++E E ++ +EE+       +L K     +K K      KK   K++ 
Sbjct: 223  FKIKTVAQKKAEKKERERKKRDEEK------AKLRK-----LKEKEELETGKKDQSKQKE 271

Query: 1140 INSSVTTETISETTEVLNEPFDNSDEERPMPQLEPTCEIEVEEDGRKPVLRKAFQHQPGK 1199
                   ET+     V       S+E+   P          E+D      +K  + + G+
Sbjct: 272  SQRKFEEETVKSKVTVDTGVIPASEEKAETPTA-------AEDDNEGDKKKKDKKKKKGE 324

Query: 1200 KRQTEEEE--GKDNHCFKNADPCRNNMNDDSSNLKEGSKDNPEPLKCKQVWPKGTKRGLS 1257
            K + E+E+  G      K        + ++    K   ++  + L+  +   K  +R   
Sbjct: 325  KEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERIKRLEELEAKRKEEERLEQ 384

Query: 1258 KWRQNK-----ERKTGFKLNLYTPPETPMEPDEQVTVEEQKETSEGKTSPS--------P 1304
            + R+ K     ERK   K       ++  E   +     +   ++G   PS        P
Sbjct: 385  EKRERKKQKEKERKERLKKEGKLLTKSQREARARAEATLKLLQAQGVEVPSKDSLPKKRP 444

Query: 1305 IRIEEEVKETGEALLPQEENRREETCAPVSPNTS--PGEKPEDDLIKPEEEEEEEEEEEE 1362
            I  +++ K+  + L  +E +   E CA V       P ++     ++PEEEE+ E+   +
Sbjct: 445  IYEDKKRKKIPQQLESKEVSESMELCAAVEVMEQGVPEKEETPPPVEPEEEEDTEDAGLD 504

Query: 1363 EEE----EEEGEEEEGGGNVEKDPDGAKSQEKEEPEISTEKEDSARLDDHEEEEEEDEEP 1418
            + E    +EE E+ EG        +    + KE PE   E+E+    ++ +EE EE+EE 
Sbjct: 505  DWEAMASDEETEKVEG--------NKVHIEVKENPEEEEEEEEE---EEEDEESEEEEEE 553

Query: 1419 SHNEDHDADDEDDSHMESAEVEKEELPRESFKEVLENQE 1457
                +    DE+D  +   +   + L ++  KE+  + E
Sbjct: 554  EGESEGSEGDEEDEKVSDEKDSGKTLDKKPSKEMSSDSE 592



 Score = 59.3 bits (142), Expect = 4e-08
 Identities = 49/159 (30%), Positives = 73/159 (45%), Gaps = 18/159 (11%)

Query: 1008 AERLMEQASCWEKEEQEILSTRANSRQSPAKVQSKNKYLHSPESRPVTGERGQLLELSKE 1067
            A  +MEQ    ++E    +          A +          E+  V G +  + E+ + 
Sbjct: 472  AVEVMEQGVPEKEETPPPVEPEEEEDTEDAGLDDWEAMASDEETEKVEGNKVHI-EVKEN 530

Query: 1068 SSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENI---QSSPPRLTKPQSVAI--- 1121
              EEEEEEE+EEE+EE EEEEE+E E E  E +EE+E +   + S   L K  S  +   
Sbjct: 531  PEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPSKEMSSD 590

Query: 1122 ----------KRKRPFVLKKKRGRKRRRINS-SVTTETI 1149
                      K +R +   K+R  KRR  +S +V TE +
Sbjct: 591  SEYDSDDDRTKEERAYDKAKRRIEKRRLEHSKNVNTEKL 629


>gi|155030232 proline, glutamic acid and leucine rich protein 1 [Homo
            sapiens]
          Length = 1130

 Score = 88.2 bits (217), Expect = 8e-17
 Identities = 98/335 (29%), Positives = 142/335 (42%), Gaps = 54/335 (16%)

Query: 1277 PETPMEPDEQVTVEEQKETSEGKTSPSPIRIEEEVKETGEAL--LPQEENRREETCAPVS 1334
            P  P  P    T      T     SP P+  +EE +E   A   LP           PV+
Sbjct: 796  PPLPPPPPSGATPPPIAPTGPPTASP-PVPAKEEPEELPAAPGPLPPPPPPPPPVPGPVT 854

Query: 1335 -------PNTSPG----EKPEDDL----IKPEEEEEEEEEEEEEEEEEEGEEEEGGGNVE 1379
                   P  +PG       E+DL    I   +EEEEEEEEEEEEEEEE EEEE     E
Sbjct: 855  LPPPQLVPEGTPGGGGPPALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEE 914

Query: 1380 KDPDGAKSQEKEEPEISTEKEDSARLDDHEEEEEEDEEPSHNEDHDADDEDDSHMESA-- 1437
            +D +    +E+EE E   E+ +    +  EEEEEEDEE    E+ + ++ +D    +A  
Sbjct: 915  EDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEE----EEEELEEVEDLEFGTAGG 970

Query: 1438 EVEKEELPRESFKEVLENQETFLDLNVQPGHSNPEVLMDC---------GVDLTASCNSE 1488
            EVE+   P  +    L   E+   +  +P    P +L++          G D   +   E
Sbjct: 971  EVEEGAPPPPTLPPALPPPESPPKVQPEP-EPEPGLLLEVEEPGTEEERGADTAPTLAPE 1029

Query: 1489 PKELAGDPEAVPESDEE-PPPGEQAQKQDQKNSKEVDTEFKEGN---------PATMEID 1538
                 G+ E   ES    PPP E  +++       ++ E ++G+         PA  E++
Sbjct: 1030 ALPSQGEVEREGESPAAGPPPQELVEEEPSAPPTLLEEETEDGSDKVQPPPETPAEEEME 1089

Query: 1539 SETVQAVQSLTQESSEQDDT------FQDCAETQE 1567
            +ET    ++   +  EQDDT      F DC    E
Sbjct: 1090 TET----EAEALQEKEQDDTAAMLADFIDCPPDDE 1120



 Score = 69.3 bits (168), Expect = 4e-11
 Identities = 70/259 (27%), Positives = 107/259 (41%), Gaps = 42/259 (16%)

Query: 1053 PVTGERGQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEE----EEEEEENIQS 1108
            P   E   ++ ++    EEEEEEE+EEEEEEEEEEEED EEEEE+E    EEEEEE  + 
Sbjct: 872  PALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEF 931

Query: 1109 SPPRLTKPQSVAIKRKRPFVLKKKRGRKRRRINSSVTTETISE------TTEVLNEPFDN 1162
                  +   +  + +     +++   +   +        + E      T      P ++
Sbjct: 932  EEEFEEEEGELEEEEEEEDEEEEEELEEVEDLEFGTAGGEVEEGAPPPPTLPPALPPPES 991

Query: 1163 SDEERPMPQLEPTCEIEVEEDGRKPVLRKAFQHQPGKKRQTEEEEGKDN--HCFKNADPC 1220
              + +P P+ EP   +EVEE G                  TEEE G D        A P 
Sbjct: 992  PPKVQPEPEPEPGLLLEVEEPG------------------TEEERGADTAPTLAPEALPS 1033

Query: 1221 RNNMNDDSSNLKEGSKDNPEPLKCKQVWPKGTKRGLSKWRQNKERKTGFKLNLYTPPETP 1280
            +  +  +  +   G    P P +  +  P      L +  ++   K      +  PPETP
Sbjct: 1034 QGEVEREGESPAAG----PPPQELVEEEPSAPPTLLEEETEDGSDK------VQPPPETP 1083

Query: 1281 MEPDEQVTVEEQKETSEGK 1299
             E  E++  E + E  + K
Sbjct: 1084 AE--EEMETETEAEALQEK 1100



 Score = 62.0 bits (149), Expect = 6e-09
 Identities = 89/357 (24%), Positives = 128/357 (35%), Gaps = 100/357 (28%)

Query: 1049 PESRPVTGERGQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQS 1108
            PE  P  G    L E     +    +EE+EEEEEEEEEEEE+EEEEE+ EEEEE+E    
Sbjct: 862  PEGTPGGGGPPALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDE---- 917

Query: 1109 SPPRLTKPQSVAIKRKRPFVLKKKRGRKRRRINSSVTTETISETTEVLNEPFDNSDEERP 1168
                                                             E F+  +EE  
Sbjct: 918  ------------------------------------------------EEYFEEEEEE-- 927

Query: 1169 MPQLEPTCEIEVEEDGRKPVLRKAFQHQPGKKRQTEEEEGKDNHCFKNADPCRN-NMNDD 1227
                    E E EE+         F+ + G+  + EEEE ++    +  +   +      
Sbjct: 928  --------EEEFEEE---------FEEEEGELEEEEEEEDEEEE--EELEEVEDLEFGTA 968

Query: 1228 SSNLKEGSKDNPEPLKCKQVWPKGTKRGLSKWRQNKERKTGFKLNLYTP-PETPMEPDEQ 1286
               ++EG+   P P       P        K +   E + G  L +  P  E     D  
Sbjct: 969  GGEVEEGA---PPPPTLPPALP--PPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTA 1023

Query: 1287 VTVEEQKETSEGKTSPSPIRIEEEVKETGEALLPQEENRREETCAPVSPNTSPGEKPED- 1345
             T+  +   S+G+       +E E +       PQE    E    P +P T   E+ ED 
Sbjct: 1024 PTLAPEALPSQGE-------VEREGESPAAGPPPQELVEEE----PSAPPTLLEEETEDG 1072

Query: 1346 -DLIKPEEEEEEEEEEEEEEEEEEGEEEEGGGN-------VEKDPDGAKSQEKEEPE 1394
             D ++P  E   EEE E E E E  +E+E           ++  PD  K     EP+
Sbjct: 1073 SDKVQPPPETPAEEEMETETEAEALQEKEQDDTAAMLADFIDCPPDDEKPPPPTEPD 1129



 Score = 53.5 bits (127), Expect = 2e-06
 Identities = 66/235 (28%), Positives = 91/235 (38%), Gaps = 43/235 (18%)

Query: 990  ILISNAAVSEEEREAEKEAERLMEQASCWEKEEQEILSTRANSRQSPAKVQSKNKYLHSP 1049
            + + N   S+EE E E+E E   E+    E+EE+E         +   + + + +     
Sbjct: 878  LTVININSSDEEEEEEEEEEEEEEE----EEEEEEDFEEEEEDEEEYFEEEEEEEEEFEE 933

Query: 1050 ESRPVTGERGQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSS 1109
            E     GE            EEEEEEEDEEEEEE EE E+ E      E EE      + 
Sbjct: 934  EFEEEEGEL-----------EEEEEEEDEEEEEELEEVEDLEFGTAGGEVEEGAPPPPTL 982

Query: 1110 PPRLTKPQSVAIKRKRP------FVLKKKRGRKRRRINSSVTT---ETISETTEVLNE-- 1158
            PP L  P+S    +  P       +  ++ G +  R   +  T   E +    EV  E  
Sbjct: 983  PPALPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAPEALPSQGEVEREGE 1042

Query: 1159 -------PFDNSDEERPMPQLEPTCEIEVEEDGRKPVLRKAFQHQPGKKRQTEEE 1206
                   P +  +EE   P   PT   E  EDG   V       QP  +   EEE
Sbjct: 1043 SPAAGPPPQELVEEE---PSAPPTLLEEETEDGSDKV-------QPPPETPAEEE 1087



 Score = 45.4 bits (106), Expect = 6e-04
 Identities = 82/345 (23%), Positives = 123/345 (35%), Gaps = 107/345 (31%)

Query: 1088 EEDEEEEEEEEEEEEEENIQSSPPRLTKPQSVAIKRKRPFVLKKKRGRKRRRINSSVTTE 1147
            +E+EEEEEEEEEEEEEE  +                                       E
Sbjct: 887  DEEEEEEEEEEEEEEEEEEEE--------------------------------------E 908

Query: 1148 TISETTEVLNEPFDNSDEERPMPQLEPTCEIEVEEDGRKPVLRKAFQHQPGKKRQTEEEE 1207
               E  E   E F+  +EE          E E EE+         F+ + G+  + EEEE
Sbjct: 909  DFEEEEEDEEEYFEEEEEE----------EEEFEEE---------FEEEEGELEEEEEEE 949

Query: 1208 GKDNHCFKNADPCRN-NMNDDSSNLKEGSKDNPEPLKCKQVWPKGTKRGLSKWRQNKERK 1266
             ++    +  +   +         ++EG+   P P       P        K +   E +
Sbjct: 950  DEEEE--EELEEVEDLEFGTAGGEVEEGA---PPPPTLPPALPP--PESPPKVQPEPEPE 1002

Query: 1267 TGFKLNLYTPPETPMEPDEQVTVEEQKETSEGKTSPSPIRIEEEVKETGEALL---PQEE 1323
             G  L          E +E  T EE+   +    +P  +  + EV+  GE+     P +E
Sbjct: 1003 PGLLL----------EVEEPGTEEERGADTAPTLAPEALPSQGEVEREGESPAAGPPPQE 1052

Query: 1324 NRREETCAPVSPNTSPGEKPED--DLIKPEEEEEEEEEEEEEEEEEEGEEEEGGGNVEKD 1381
               EE   P +P T   E+ ED  D ++P  E   EEE E E E E              
Sbjct: 1053 LVEEE---PSAPPTLLEEETEDGSDKVQPPPETPAEEEMETETEAEA------------- 1096

Query: 1382 PDGAKSQEKEEPEISTEKEDSARLDDHEEEEEEDEEPSHNEDHDA 1426
                  QEKE+       + +A L D  +   +DE+P    + D+
Sbjct: 1097 -----LQEKEQ------DDTAAMLADFIDCPPDDEKPPPPTEPDS 1130



 Score = 32.7 bits (73), Expect = 3.8
 Identities = 18/57 (31%), Positives = 24/57 (42%), Gaps = 6/57 (10%)

Query: 1846 SASLSTPLSNTGL------VQLSQSPHSVPGGPQAQATMTPPPNLTPPPMNLPPPLL 1896
            S +   P++ TG       V   + P  +P  P       PPP   P P+ LPPP L
Sbjct: 804  SGATPPPIAPTGPPTASPPVPAKEEPEELPAAPGPLPPPPPPPPPVPGPVTLPPPQL 860


>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
            sapiens]
          Length = 750

 Score = 87.0 bits (214), Expect = 2e-16
 Identities = 98/471 (20%), Positives = 201/471 (42%), Gaps = 49/471 (10%)

Query: 997  VSEEEREAEKEAERLMEQASCWEKEEQEILSTRANSRQSPAKVQSKNKYLHSPESRPVTG 1056
            + E+E +  ++ E++ EQ     ++E+ +       R+    +  K + +   E   +  
Sbjct: 316  IQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEE--MMW 373

Query: 1057 ERGQLLELSKESSEEEEEE--EDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLT 1114
            E+ + +   +E   E+EE+  E EE+  E+E+  E EE+ +EEE+  E+E  Q    ++ 
Sbjct: 374  EKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMW 433

Query: 1115 KPQSVAIKRKRPFVLKKKRGRKRRRINSSVTTETISETTEVLNEPFDNSDEERPMPQLEP 1174
            + Q   I+ +   + ++++   R+        E I E  ++  E  +   E+  M + E 
Sbjct: 434  R-QEEKIREQEEKIREQEKKMWRQE-------EKIHEQEKIREE--EKRQEQEEMWRQEE 483

Query: 1175 TCEIEVEEDGRKPVLRKAFQHQPGKKRQTEEEEGKDNHCFKNADPCRNNMNDDSSNLKEG 1234
                E EE  R+   ++    Q  K R+ EE+  +     +  +       +     +E 
Sbjct: 484  KIH-EQEEIWRQ---KEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEK 539

Query: 1235 SKDNPEPLKCKQVWPKGTKRGLSKWRQNKERKTGFKLNLYTPPETPMEPDEQVTVEEQKE 1294
             ++  E  + ++   +  K    + RQ +E K      ++   E   E +E+V  +E+K 
Sbjct: 540  IREQEEMWREEEKMHEQEKIWEEEKRQEQEDK------MWRQEEKIREQEEKVWRQEEKI 593

Query: 1295 TSEGKTSPSPIRIEEEVKETGEALLPQEENRREETCAPVSPNTSPGEKPEDDLIKPEEEE 1354
              +          EE+ +E  E +  QEE  RE+               E+ + + EE+ 
Sbjct: 594  REQ----------EEKRQEQEEKMWKQEEKIREQ---------------EEKIQEQEEKI 628

Query: 1355 EEEEEEEEEEEEEEGEEEEGGGNVEKDPDGAKSQEKEEPEISTEKEDSARLDDHEEEEEE 1414
             E+EE+  E+EE   E+EE  G  E+     + + +E+ E    +E+  R  + +  E+E
Sbjct: 629  REQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQE 688

Query: 1415 DEEPSHNEDHDADDEDDSHMESAEVEKEELPRESFKEVLENQETFLDLNVQ 1465
            ++     E     +E     E    E+EE  +E  +++   +E   +  V+
Sbjct: 689  EKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVR 739



 Score = 83.2 bits (204), Expect = 2e-15
 Identities = 101/471 (21%), Positives = 199/471 (42%), Gaps = 59/471 (12%)

Query: 994  NAAVSEEEREAEKEAERLMEQASCWEKEEQEILSTRANSRQSPAKVQSKNKYLHSPESRP 1053
            N    ++E +  ++ E++ E     +++E++I       R+   K++ + + +   E + 
Sbjct: 292  NRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKM 351

Query: 1054 VTGERGQLLELSKESSEEEEEEEDEEEEEEEEEE--EEDEEEEEEEEEEEEEENIQSSPP 1111
               E     +  K   +EE   E EE+   +EE   E++E+  E EE+  E+E I+    
Sbjct: 352  RRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEE 411

Query: 1112 RLTKPQSVAIKRKRPFVLKKKRGRKRRRINSSVTTETISETTEVLNEPFDNSDEERPMPQ 1171
                      KR+    ++++  R+ +        E I E  E + E      E++   Q
Sbjct: 412  ----------KRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIRE-----QEKKMWRQ 456

Query: 1172 LEPTCEIEVEEDGRKPVLRKAFQHQPGKKRQTEEEEGKDNHCFKNADPCRNNMNDDSSNL 1231
             E   E E   +  K   ++    Q  K  + EE   +     +  +  R          
Sbjct: 457  EEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIR---------- 506

Query: 1232 KEGSKDNPEPLKCKQVWPKGTKRGLSKWRQNKERKTGFKLNLYTPPETPMEPDEQVTVEE 1291
            K+  K   +  K ++   K  ++    WRQ ++ +   ++      E  M   E++  EE
Sbjct: 507  KQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEM---WREEEKMHEQEKIWEEE 563

Query: 1292 QKETSEGKTSPSPIRIEEEVKETGEALLPQEENRREETCAPVSPNTSPGEKPEDDLIKPE 1351
            +++  E K      R EE+++E  E +  QEE  RE+            ++ E+ + K E
Sbjct: 564  KRQEQEDKM----WRQEEKIREQEEKVWRQEEKIREQ--------EEKRQEQEEKMWKQE 611

Query: 1352 EEEEEEEEEEEEEEEEEGEEEEGGGNVEKDPDGAKSQEKEEPEISTEK---EDSARLDDH 1408
            E+  E+EE+ +E+EE+  E+EE            K +E+EE     E+   E   ++ + 
Sbjct: 612  EKIREQEEKIQEQEEKIREQEE------------KIREQEEMTQEQEEKMGEQEEKMCEQ 659

Query: 1409 EEEEEEDEEPSHNEDHDADDEDDSHMESAEV--EKEELPRESFKEVLENQE 1457
            EE+ +E EE    ++    +++    E  E   E+EE+ +E  +++ E +E
Sbjct: 660  EEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEE 710



 Score = 82.8 bits (203), Expect = 3e-15
 Identities = 100/466 (21%), Positives = 202/466 (43%), Gaps = 43/466 (9%)

Query: 997  VSEEEREAEKEAERLMEQASCWEKEEQEILSTRANSRQSPAKVQSKNKYLHSPESRPVTG 1056
            + E E + +++ E++ EQ     ++E+++        +   K++ + + +   E +    
Sbjct: 309  IQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQ 368

Query: 1057 ERGQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEE-EEEENIQSSPPRLTK 1115
            E     +  K   +EE   E EE+  E EE+  ++E+  E+EE+ +EEE I+    R  +
Sbjct: 369  EEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKR--Q 426

Query: 1116 PQSVAIKRKRPFVLKKKRGRKRRRINSSVTTETISETTEVLNEPFDNSDEERPMPQLEPT 1175
             Q   + R+   + +++   + +        E I E  ++  E  +   E+  M + E  
Sbjct: 427  EQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREE--EKRQEQEEMWRQEEK 484

Query: 1176 CEIEVEEDGRKPVLRKAFQHQPGKKRQTEEEEGKDNHCFKNADPCRNNMNDDSSNLKEGS 1235
               E EE  R+   ++    Q  K R+ EE+  +     +  +       +     +E  
Sbjct: 485  IH-EQEEIWRQ---KEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKI 540

Query: 1236 KDNPEPLKCKQVWPKGTKRGLSKWRQNKERKTGFKLNLYTPPETPMEPDEQVTVEEQKET 1295
            ++  E  + ++   +  K    + RQ +E K      ++   E   E +E+V  +E+K  
Sbjct: 541  REQEEMWREEEKMHEQEKIWEEEKRQEQEDK------MWRQEEKIREQEEKVWRQEEKIR 594

Query: 1296 SEGKTSPSPIRIEEEVKETGEALLPQEENRREETCAPVSPNTSPGEKPEDDLIKPEEEEE 1355
             +          EE+ +E  E +  QEE  RE+            ++ E+ + + EE+  
Sbjct: 595  EQ----------EEKRQEQEEKMWKQEEKIREQ--------EEKIQEQEEKIREQEEKIR 636

Query: 1356 EEEEEEEEEEEEEGEEEEGGGNVEKDPDGAKSQEKEEPEISTE---KEDSARLDDHEEEE 1412
            E+EE  +E+EE+ GE+EE     E+     K QE+EE     E   +E   ++ + EE+ 
Sbjct: 637  EQEEMTQEQEEKMGEQEEKMCEQEE-----KMQEQEETMWRQEEKIREQEKKIREQEEKI 691

Query: 1413 EEDEEPSHNEDHDADDEDDSHMESAE--VEKEELPRESFKEVLENQ 1456
             E EE    ++    ++++   E  E   E+EE  R   +++ E +
Sbjct: 692  REQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQE 737



 Score = 79.7 bits (195), Expect = 3e-14
 Identities = 99/480 (20%), Positives = 210/480 (43%), Gaps = 29/480 (6%)

Query: 1001 EREAEKEAERLMEQASCWEKEEQEILSTRANSRQSPAKVQSKNKYLHSPESRPVTGERGQ 1060
            + E +++  +L E+    E E+ EI   + N ++   K++     L   + +      G+
Sbjct: 216  DEELKEKNAKLQEKLQLVESEKSEI---QLNVKELKRKLERAKLLLPQQQLQAEADHLGK 272

Query: 1061 LLELSKESSEEEEEEED-----EEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTK 1115
             L+      + + EE +      +++EE+   +E++ +E EE+ +E+EE I+    ++ +
Sbjct: 273  ELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKI-R 331

Query: 1116 PQSVAIKRKRPFVLKKKRGRKRRRINSSVTTETISETTEVLNEPFDNS--DEERPMPQLE 1173
             Q   ++R+   + +K+   +R+        E +    E++ E  +     EE    + E
Sbjct: 332  EQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEE 391

Query: 1174 PTCEIEVEEDGRKPVLRKAFQHQPGKK-RQTEEEEGKDNHCFKNADPCRNNMNDDSSNLK 1232
               E+E +   ++ +  +  + Q  +K R+ E+ + ++   ++  +  R          K
Sbjct: 392  KIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEK 451

Query: 1233 EGSKDNPEPLKCKQVWPKGTKRGLSK-WRQNKERKTGFKLNLYTPPETPMEPDEQVTVEE 1291
            +  +   +  + +++  +  ++   + WRQ  E K   +  ++   E   E +E++  +E
Sbjct: 452  KMWRQEEKIHEQEKIREEEKRQEQEEMWRQ--EEKIHEQEEIWRQKEKMHEQEEKIRKQE 509

Query: 1292 QKE-TSEGKTSPSPIRI---EEEVKETGEALLPQEENRREETCAPVSPNTSPGEK---PE 1344
            +K    E K      +I   EE++    E +  QEE  REE            EK    E
Sbjct: 510  EKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQE 569

Query: 1345 DDLIKPEEEEEEEEE----EEE---EEEEEEGEEEEGGGNVEKDPDGAKSQEKEEPEIST 1397
            D + + EE+  E+EE    +EE   E+EE+  E+EE     E+     + + +E+ E   
Sbjct: 570  DKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIR 629

Query: 1398 EKEDSARLDDHEEEEEEDEEPSHNEDHDADDEDDSHMESAEVEKEELPRESFKEVLENQE 1457
            E+E+  R  +   +E+E++     E     +E     E     +EE  RE  K++ E +E
Sbjct: 630  EQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEE 689



 Score = 78.6 bits (192), Expect = 6e-14
 Identities = 95/437 (21%), Positives = 182/437 (41%), Gaps = 76/437 (17%)

Query: 999  EEEREAEKEAERLMEQASCWEKEE-----------QEILSTRANSRQSPAKVQSKNKYLH 1047
            +EE   EKE +   ++   WEKEE           QE +  +   RQ   K++ + K   
Sbjct: 368  QEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQE 427

Query: 1048 SP-----ESRPVTGERGQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEE 1102
                   +   +  +  ++ E  K+   +EE+  ++E+  EEE+ +E EE   +EE+  E
Sbjct: 428  QEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHE 487

Query: 1103 EENIQSSPPRLTKPQSVAIKRKRPFVLKKKRGRKRRRINSSVTTETISETTEVLNEPFDN 1162
            +E I     ++ + Q   I+++   V +++   + +        E +    E + E  + 
Sbjct: 488  QEEIWRQKEKMHE-QEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEM 546

Query: 1163 SDEERPMPQLEPTCEIEVEEDGRKPVLRKAFQHQPGKKRQTEEEEGKDNHCFKNADPCRN 1222
              EE  M + E   E E  ++    + R     Q  K R+ EE+  +     +  +  R 
Sbjct: 547  WREEEKMHEQEKIWEEEKRQEQEDKMWR-----QEEKIREQEEKVWRQEEKIREQEEKRQ 601

Query: 1223 NMNDDSSNLKEGSKDNPEPLKCKQVWPKGTKRGLSKWRQNKERKTGFKLNLYTPPETPME 1282
               +     +E  ++  E ++ ++           K R+ +E+       +    E   E
Sbjct: 602  EQEEKMWKQEEKIREQEEKIQEQE----------EKIREQEEK-------IREQEEMTQE 644

Query: 1283 PDEQVTVEEQKETSEGKTSPSPIRIEEEVKETGEALLPQEENRREETCAPVSPNTSPGEK 1342
             +E++  +E+K   +          EE+++E  E +  QEE  RE+             +
Sbjct: 645  QEEKMGEQEEKMCEQ----------EEKMQEQEETMWRQEEKIREQ---------EKKIR 685

Query: 1343 PEDDLIKPEEEEEEEEEEEE--EEEEEEGEEEEGGGNVEKDPDGAKSQEKEEPEISTEK- 1399
             +++ I+ E+EE  +E+EE+  E+EE+  E+EE            K QE+EE     E+ 
Sbjct: 686  EQEEKIR-EQEEMMQEQEEKMWEQEEKMCEQEE------------KMQEQEEKMRRQEEK 732

Query: 1400 --EDSARLDDHEEEEEE 1414
              E   RL   EE+ +E
Sbjct: 733  MWEQEVRLRQQEEKMQE 749



 Score = 70.1 bits (170), Expect = 2e-11
 Identities = 123/632 (19%), Positives = 254/632 (40%), Gaps = 72/632 (11%)

Query: 958  IRREKLILSHMEKLKTCSRANELDPDSLRWTPILISNAAVSEEEREAEKEAERLMEQASC 1017
            +RRE     H  ++ TC +  EL         +  S  AV + E EA     RL +    
Sbjct: 121  LRRELEAQVHTIRILTCQKT-ELQ------MALYYSQHAVKQLEGEARDLISRLHDSWKF 173

Query: 1018 WEKEEQEILSTRANSRQSPAKVQSKNKYLHSPESRPVTGERGQL-LELSKESSEEEEEEE 1076
              + EQ + +     +++   ++             +T ER  L LEL + +  +EE +E
Sbjct: 174  AGELEQALSAVATQKKKADRYIEE------------LTKERDALSLELYRNTITDEELKE 221

Query: 1077 DEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQSVAIKRKRPFVLKKKRGRK 1136
               + +E+ +  E E+ E +   +E +  ++ +   L + Q  A             G++
Sbjct: 222  KNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQA--------EADHLGKE 273

Query: 1137 RRRINSSVTTETISETTEVLNEPFDNSDEERPMPQLEPTCEIEVEEDGRKPVLR---KAF 1193
             + +++ +  +   E  E+ N   +   EE+   Q E   E E +   ++  +R   +  
Sbjct: 274  LQSVSAKLQAQV--EENELWNR-LNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKI 330

Query: 1194 QHQPGKKRQTEEEEGKDNHCFKNADPCRNNMNDDSSNLKEGSKDNPEPLKCKQ--VWPKG 1251
            + Q  K R+ EE   +     +  +       +     +E   +  E ++ ++  +W K 
Sbjct: 331  REQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKE 390

Query: 1252 TK-RGLSKWRQNKERKTGFKLNLYTPPETPMEPDEQVTVEEQKETSEGKTSPSPIRIEEE 1310
             K R L +    +E+            E   + +E++  +E+++  E K      R EE+
Sbjct: 391  EKIRELEEKMHEQEK--------IREQEEKRQEEEKIREQEKRQEQEAKM----WRQEEK 438

Query: 1311 VKETGEALLPQEEN--RREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEEE 1368
            ++E  E +  QE+   R+EE            ++ E + +  +EE+  E+EE   ++E+ 
Sbjct: 439  IREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKM 498

Query: 1369 GEEEEGGGNVEKDPDGAKSQE----KEEPEISTEKEDSARLDDHEEEEEE---DEEPSHN 1421
             E+EE    + K  +    QE    ++E +I  ++E   R ++   E+EE   +EE  H 
Sbjct: 499  HEQEE---KIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHE 555

Query: 1422 EDHDADDEDDSHMESAEVEKEELPRESFKEVLENQETFLDLNVQPGHSNPEVLMDCGVDL 1481
            ++   ++E     E     +EE  RE  ++V   +E   +   +      ++        
Sbjct: 556  QEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQ----- 610

Query: 1482 TASCNSEPKELAGDPEAVPESDE-----EPPPGEQAQKQDQKNSKEVDTEFK-EGNPATM 1535
                  + +++    E + E +E     E    EQ +K  ++  K  + E K +    TM
Sbjct: 611  EEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETM 670

Query: 1536 EIDSETVQAVQSLTQESSEQDDTFQDCAETQE 1567
                E ++  +   +E  E+    ++  + QE
Sbjct: 671  WRQEEKIREQEKKIREQEEKIREQEEMMQEQE 702



 Score = 43.5 bits (101), Expect = 0.002
 Identities = 22/107 (20%), Positives = 53/107 (49%)

Query: 999  EEEREAEKEAERLMEQASCWEKEEQEILSTRANSRQSPAKVQSKNKYLHSPESRPVTGER 1058
            E+E +  ++ E++ EQ    +++E+ +       R+   K++ + + +   E      E 
Sbjct: 644  EQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEE 703

Query: 1059 GQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEN 1105
                +  K   +EE+ +E EE+   +EE+  ++E    ++EE+ +E+
Sbjct: 704  KMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEH 750


>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 [Homo
            sapiens]
          Length = 916

 Score = 84.0 bits (206), Expect = 1e-15
 Identities = 108/465 (23%), Positives = 181/465 (38%), Gaps = 87/465 (18%)

Query: 991  LISNAAVSEEEREAEKEAERLMEQASCWEKEEQEILSTRANSRQSPAKVQSKNKYLHSPE 1050
            +I    V +E+ E E+    + E+ +   KEE++     A  ++   + + +     + +
Sbjct: 456  IIEETKVEDEKSEMEEALTAITEELAVSMKEEKK---EAAEEKEEEPEAEEEEV---AAK 509

Query: 1051 SRPVTGERGQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEE---EEEEEEEEEENIQ 1107
              PV   +    E+ +E  E+EEEE  EEEEEE+E  + D+ EE   E+E   E+EE  Q
Sbjct: 510  KSPV---KATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQ 566

Query: 1108 SSPPRLTKPQSVAIKRKRPFVLKKKRGRKRRRINSSVTTETISETTEVLNEPFDNSDEER 1167
                   + +    + K    +++K                 SE      E   ++  E+
Sbjct: 567  EEGETEAEAEGEEAEAKEEKKVEEK-----------------SEEVATKEELVADAKVEK 609

Query: 1168 PMPQLEPTCEIEVEEDGRKPVLRKAFQHQPGKK---RQTEEEEGKDNHCFKNADPCRNNM 1224
            P     P  +  VEE G+ PV +   + + GK    +   EE+GK         P   + 
Sbjct: 610  PEKAKSPVPKSPVEEKGKSPVPKSPVEEK-GKSPVPKSPVEEKGKS--------PVPKSP 660

Query: 1225 NDDSSNLKEGSKDNPEPLKCKQVWPKG------TKRGLSKWRQNKERKTGFKLNLYTPPE 1278
             ++    K     +P   K K   PK       +K  + K  Q +E +   K       E
Sbjct: 661  VEEKG--KSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVK-------E 711

Query: 1279 TPMEPDEQVTVEEQKETSEGKTSPSPIRIEEEVKETGEALLPQEENRREETCAPVSPNTS 1338
             P E   +   E+ K+  E K + SP++                    EE  A V   T 
Sbjct: 712  APKEEKVEKKEEKPKDVPEKKKAESPVK--------------------EEAVAEVVTITK 751

Query: 1339 PGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGEEEEGGGNVEKDPDGAKSQEKEEPEISTE 1398
              +      +  E+E +EE +  ++E+E+E    EGG   E    GAK   KE+  ++ E
Sbjct: 752  SVK------VHLEKETKEEGKPLQQEKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGE 805

Query: 1399 KEDSARLDDHEEE-----EEEDEEPSHNEDHDADDEDDSHMESAE 1438
             E    ++   +E     EEE    ++  D    DE     +S E
Sbjct: 806  VEGKEEVEQETKEKGSGREEEKGVVTNGLDLSPADEKKGGDKSEE 850



 Score = 83.6 bits (205), Expect = 2e-15
 Identities = 105/460 (22%), Positives = 185/460 (40%), Gaps = 69/460 (15%)

Query: 1006 KEAERLMEQASCW-EKEEQEILSTRANSRQSPAKVQSKNKYLHSPESRPVTGERGQLLEL 1064
            K  E ++E+     EK E E   T      + +  + K +     E  P   E     + 
Sbjct: 451  KFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKK 510

Query: 1065 SKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQSVAIKRK 1124
            S   +   E +E+E E+EEEE +EE+EEE+E  + ++ EE          K +    + +
Sbjct: 511  SPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGE 570

Query: 1125 RPFVLKKKRGRKRRRINSSVTTETISETTEVLNEPFDNSDEERPMPQLEPTCEIEVEEDG 1184
                 + +    +        +E ++   E++ +    +  E+P     P  +  VEE G
Sbjct: 571  TEAEAEGEEAEAKEEKKVEEKSEEVATKEELVAD----AKVEKPEKAKSPVPKSPVEEKG 626

Query: 1185 RKPVLRKAFQHQPGKK---RQTEEEEGKDNHCFKNADPCRNNMNDDSSNLKEGSKDNPEP 1241
            + PV +   + + GK    +   EE+GK +   K+    +       S ++E +K    P
Sbjct: 627  KSPVPKSPVE-EKGKSPVPKSPVEEKGK-SPVPKSPVEEKGKSPVSKSPVEEKAK---SP 681

Query: 1242 LKCKQVWPKGTKRGLSKWRQNKERKTGFKLNLYTPPETPMEPDEQVTVEEQKETSEGKTS 1301
            +    V    +K  + K  Q +E +   K       E P E   +   E+ K+  E K +
Sbjct: 682  VPKSPVEEAKSKAEVGKGEQKEEEEKEVK-------EAPKEEKVEKKEEKPKDVPEKKKA 734

Query: 1302 PSPIR-----------------IEEEVKETGEALLPQEENRREETCA------PVSPNTS 1338
             SP++                 +E+E KE G+ L  Q+E  +E+           S   +
Sbjct: 735  ESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPL--QQEKEKEKAGGEGGSEEEGSDKGA 792

Query: 1339 PGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGEEEEGG-------GNVEKDPDGAKSQE-- 1389
             G + ED  +  E E +EE E+E +E+    EEE+G           ++   G KS+E  
Sbjct: 793  KGSRKEDIAVNGEVEGKEEVEQETKEKGSGREEEKGVVTNGLDLSPADEKKGGDKSEEKV 852

Query: 1390 ---KEEPEISTEKEDSA------------RLDDHEEEEEE 1414
               K   +I++E  D A            ++++HEE  EE
Sbjct: 853  VVTKTVEKITSEGGDGATKYITKSVTVTQKVEEHEETFEE 892



 Score = 72.4 bits (176), Expect = 4e-12
 Identities = 54/173 (31%), Positives = 86/173 (49%), Gaps = 12/173 (6%)

Query: 1285 EQVTVEEQKETSEGK----TSPSPIRIEEEVKETGEALLPQEENRREETCAPVSPNTSPG 1340
            E+  VE++K   E      T    + ++EE KE  E    + E   EE  A  SP  +  
Sbjct: 458  EETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATA 517

Query: 1341 EKPEDDLIKPEEEEEEEEEEEEEEEEEEGEEEEGGGNVEKDPDGAKSQ-EKEEPEISTEK 1399
             + +++  + EEEE +EEEEEE+E  +  + EEGG   EK+    K + E+EE E   E 
Sbjct: 518  PEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGS--EKEGSSEKEEGEQEEGETEAEA 575

Query: 1400 E-DSARLDDHEEEEEEDEEPSHNEDHDADDEDDSHMESAEVEKEELPRESFKE 1451
            E + A   + ++ EE+ EE +  E+  A    D+ +E  E  K  +P+   +E
Sbjct: 576  EGEEAEAKEEKKVEEKSEEVATKEELVA----DAKVEKPEKAKSPVPKSPVEE 624



 Score = 42.7 bits (99), Expect = 0.004
 Identities = 119/613 (19%), Positives = 218/613 (35%), Gaps = 89/613 (14%)

Query: 1003 EAEKEAERLMEQ-ASCWEKEEQEILSTRANSRQSPAKVQSKNKYLHSPESRPVTGERGQL 1061
            E +K+ + L ++ A      E+E+    A  + S   V+ K+ YL +  S  +   R QL
Sbjct: 219  ELDKKVQSLQDEVAFLRSNHEEEVADLLAQIQASHITVERKD-YLKTDISTALKEIRSQL 277

Query: 1062 LELSKESSEEEEE-------EEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLT 1114
               S ++  + EE       +  E  E+ +E     +EE  E   + + ++I+    R T
Sbjct: 278  ESHSDQNMHQAEEWFKCRYAKLTEAAEQNKEAIRSAKEEIAEYRRQLQSKSIELESVRGT 337

Query: 1115 KPQSVAIKRKRPFVLKKKRGRKRRRINSSVTTETISETTEVLN----EPFDNSDEERPMP 1170
            K    +++R+   +       +R   + S   +TI +    L     E   +  E + + 
Sbjct: 338  KE---SLERQLSDI------EERHNHDLSSYQDTIQQLENELRGTKWEMARHLREYQDLL 388

Query: 1171 QLEPTCEIEVEE-----DGRKP--------VLRKAFQHQPG-------KKRQTEEEEGKD 1210
             ++   +IE+       +G +         +    + H+P        +K + E  + K 
Sbjct: 389  NVKMALDIEIAAYRKLLEGEETRFSTFAGSITGPLYTHRPPITISSKIQKPKVEAPKLKV 448

Query: 1211 NHCFKNADPCRNNMNDDSSNLKEGSKDNPEPLKC------KQVWPKGTKRGLSKWRQNKE 1264
             H F         + D+ S ++E      E L        K+   +  +   ++  +   
Sbjct: 449  QHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAA 508

Query: 1265 RKTGFKLNLYTPPETPMEPDEQVTVEEQKETSEGKTSPSPIRIEEEVKETGEALLPQEEN 1324
            +K+  K       E   E +E+   EE++E  EG  S       EE     E    +EE 
Sbjct: 509  KKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQA----EEGGSEKEGSSEKEEG 564

Query: 1325 RREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEE-------EEEEE----------EE 1367
             +EE            E  E+  ++ + EE   +EE       E+ E+          EE
Sbjct: 565  EQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEE 624

Query: 1368 EGE--------EEEGGGNVEKDPDGAKSQEKEEPEISTEKEDSARLDDHEEE-------- 1411
            +G+        EE+G   V K P   K +         EK  S       EE        
Sbjct: 625  KGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPK 684

Query: 1412 ---EEEDEEPSHNEDHDADDEDDSHMESAEVEKEELPRESFKEVLENQETFLDLNVQPGH 1468
               EE   +    +    ++E+    E+ + EK E   E  K+V E ++    +  +   
Sbjct: 685  SPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVA 744

Query: 1469 SNPEVLMDCGVDLTASCNSEPKELAGDPEAVPESDEEPPPGEQAQKQDQKNSKEVDTEFK 1528
                +     V L      E K L  + E   ++  E    E+   +  K S++ D    
Sbjct: 745  EVVTITKSVKVHLEKETKEEGKPLQQEKEK-EKAGGEGGSEEEGSDKGAKGSRKEDIAVN 803

Query: 1529 EGNPATMEIDSET 1541
                   E++ ET
Sbjct: 804  GEVEGKEEVEQET 816


>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 [Homo
            sapiens]
          Length = 540

 Score = 84.0 bits (206), Expect = 1e-15
 Identities = 108/465 (23%), Positives = 181/465 (38%), Gaps = 87/465 (18%)

Query: 991  LISNAAVSEEEREAEKEAERLMEQASCWEKEEQEILSTRANSRQSPAKVQSKNKYLHSPE 1050
            +I    V +E+ E E+    + E+ +   KEE++     A  ++   + + +     + +
Sbjct: 80   IIEETKVEDEKSEMEEALTAITEELAVSMKEEKK---EAAEEKEEEPEAEEEEV---AAK 133

Query: 1051 SRPVTGERGQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEE---EEEEEEEEEENIQ 1107
              PV   +    E+ +E  E+EEEE  EEEEEE+E  + D+ EE   E+E   E+EE  Q
Sbjct: 134  KSPV---KATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQ 190

Query: 1108 SSPPRLTKPQSVAIKRKRPFVLKKKRGRKRRRINSSVTTETISETTEVLNEPFDNSDEER 1167
                   + +    + K    +++K                 SE      E   ++  E+
Sbjct: 191  EEGETEAEAEGEEAEAKEEKKVEEK-----------------SEEVATKEELVADAKVEK 233

Query: 1168 PMPQLEPTCEIEVEEDGRKPVLRKAFQHQPGKK---RQTEEEEGKDNHCFKNADPCRNNM 1224
            P     P  +  VEE G+ PV +   + + GK    +   EE+GK         P   + 
Sbjct: 234  PEKAKSPVPKSPVEEKGKSPVPKSPVEEK-GKSPVPKSPVEEKGKS--------PVPKSP 284

Query: 1225 NDDSSNLKEGSKDNPEPLKCKQVWPKG------TKRGLSKWRQNKERKTGFKLNLYTPPE 1278
             ++    K     +P   K K   PK       +K  + K  Q +E +   K       E
Sbjct: 285  VEEKG--KSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVK-------E 335

Query: 1279 TPMEPDEQVTVEEQKETSEGKTSPSPIRIEEEVKETGEALLPQEENRREETCAPVSPNTS 1338
             P E   +   E+ K+  E K + SP++                    EE  A V   T 
Sbjct: 336  APKEEKVEKKEEKPKDVPEKKKAESPVK--------------------EEAVAEVVTITK 375

Query: 1339 PGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGEEEEGGGNVEKDPDGAKSQEKEEPEISTE 1398
              +      +  E+E +EE +  ++E+E+E    EGG   E    GAK   KE+  ++ E
Sbjct: 376  SVK------VHLEKETKEEGKPLQQEKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGE 429

Query: 1399 KEDSARLDDHEEE-----EEEDEEPSHNEDHDADDEDDSHMESAE 1438
             E    ++   +E     EEE    ++  D    DE     +S E
Sbjct: 430  VEGKEEVEQETKEKGSGREEEKGVVTNGLDLSPADEKKGGDKSEE 474



 Score = 83.6 bits (205), Expect = 2e-15
 Identities = 105/460 (22%), Positives = 185/460 (40%), Gaps = 69/460 (15%)

Query: 1006 KEAERLMEQASCW-EKEEQEILSTRANSRQSPAKVQSKNKYLHSPESRPVTGERGQLLEL 1064
            K  E ++E+     EK E E   T      + +  + K +     E  P   E     + 
Sbjct: 75   KFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKK 134

Query: 1065 SKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQSVAIKRK 1124
            S   +   E +E+E E+EEEE +EE+EEE+E  + ++ EE          K +    + +
Sbjct: 135  SPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGE 194

Query: 1125 RPFVLKKKRGRKRRRINSSVTTETISETTEVLNEPFDNSDEERPMPQLEPTCEIEVEEDG 1184
                 + +    +        +E ++   E++ +    +  E+P     P  +  VEE G
Sbjct: 195  TEAEAEGEEAEAKEEKKVEEKSEEVATKEELVAD----AKVEKPEKAKSPVPKSPVEEKG 250

Query: 1185 RKPVLRKAFQHQPGKK---RQTEEEEGKDNHCFKNADPCRNNMNDDSSNLKEGSKDNPEP 1241
            + PV +   + + GK    +   EE+GK +   K+    +       S ++E +K    P
Sbjct: 251  KSPVPKSPVE-EKGKSPVPKSPVEEKGK-SPVPKSPVEEKGKSPVSKSPVEEKAK---SP 305

Query: 1242 LKCKQVWPKGTKRGLSKWRQNKERKTGFKLNLYTPPETPMEPDEQVTVEEQKETSEGKTS 1301
            +    V    +K  + K  Q +E +   K       E P E   +   E+ K+  E K +
Sbjct: 306  VPKSPVEEAKSKAEVGKGEQKEEEEKEVK-------EAPKEEKVEKKEEKPKDVPEKKKA 358

Query: 1302 PSPIR-----------------IEEEVKETGEALLPQEENRREETCA------PVSPNTS 1338
             SP++                 +E+E KE G+ L  Q+E  +E+           S   +
Sbjct: 359  ESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPL--QQEKEKEKAGGEGGSEEEGSDKGA 416

Query: 1339 PGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGEEEEGG-------GNVEKDPDGAKSQE-- 1389
             G + ED  +  E E +EE E+E +E+    EEE+G           ++   G KS+E  
Sbjct: 417  KGSRKEDIAVNGEVEGKEEVEQETKEKGSGREEEKGVVTNGLDLSPADEKKGGDKSEEKV 476

Query: 1390 ---KEEPEISTEKEDSA------------RLDDHEEEEEE 1414
               K   +I++E  D A            ++++HEE  EE
Sbjct: 477  VVTKTVEKITSEGGDGATKYITKSVTVTQKVEEHEETFEE 516



 Score = 72.4 bits (176), Expect = 4e-12
 Identities = 54/173 (31%), Positives = 86/173 (49%), Gaps = 12/173 (6%)

Query: 1285 EQVTVEEQKETSEGK----TSPSPIRIEEEVKETGEALLPQEENRREETCAPVSPNTSPG 1340
            E+  VE++K   E      T    + ++EE KE  E    + E   EE  A  SP  +  
Sbjct: 82   EETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATA 141

Query: 1341 EKPEDDLIKPEEEEEEEEEEEEEEEEEEGEEEEGGGNVEKDPDGAKSQ-EKEEPEISTEK 1399
             + +++  + EEEE +EEEEEE+E  +  + EEGG   EK+    K + E+EE E   E 
Sbjct: 142  PEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGS--EKEGSSEKEEGEQEEGETEAEA 199

Query: 1400 E-DSARLDDHEEEEEEDEEPSHNEDHDADDEDDSHMESAEVEKEELPRESFKE 1451
            E + A   + ++ EE+ EE +  E+  A    D+ +E  E  K  +P+   +E
Sbjct: 200  EGEEAEAKEEKKVEEKSEEVATKEELVA----DAKVEKPEKAKSPVPKSPVEE 248



 Score = 38.1 bits (87), Expect = 0.090
 Identities = 65/303 (21%), Positives = 103/303 (33%), Gaps = 38/303 (12%)

Query: 1275 TPPETPMEPDEQVTVEEQKETSEGKTSPSPIRIEEEVKETGEALLPQEENRREETCAPVS 1334
            T PE   E  E+   E Q+E  E        + EE   E  E    +EE  +EE      
Sbjct: 140  TAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEK-EGSSEKEEGEQEEGETEAE 198

Query: 1335 PNTSPGEKPEDDLIKPEEEEEEEEEE-------EEEEE----------EEEGE------- 1370
                  E  E+  ++ + EE   +EE       E+ E+          EE+G+       
Sbjct: 199  AEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSP 258

Query: 1371 -EEEGGGNVEKDPDGAKSQEKEEPEISTEKEDSARLDDHEEE-----------EEEDEEP 1418
             EE+G   V K P   K +         EK  S       EE           EE   + 
Sbjct: 259  VEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKA 318

Query: 1419 SHNEDHDADDEDDSHMESAEVEKEELPRESFKEVLENQETFLDLNVQPGHSNPEVLMDCG 1478
               +    ++E+    E+ + EK E   E  K+V E ++    +  +       +     
Sbjct: 319  EVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVK 378

Query: 1479 VDLTASCNSEPKELAGDPEAVPESDEEPPPGEQAQKQDQKNSKEVDTEFKEGNPATMEID 1538
            V L      E K L  + E   ++  E    E+   +  K S++ D           E++
Sbjct: 379  VHLEKETKEEGKPLQQEKEK-EKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEVE 437

Query: 1539 SET 1541
             ET
Sbjct: 438  QET 440


>gi|95147555 microtubule-associated protein 1A [Homo sapiens]
          Length = 2803

 Score = 82.8 bits (203), Expect = 3e-15
 Identities = 145/671 (21%), Positives = 257/671 (38%), Gaps = 84/671 (12%)

Query: 1022 EQEILSTRANSRQSPAKVQSKNKYLHSPESRPVTGERGQLLELSKESSEEEEEEEDEEEE 1081
            ++++ S    +   P+K++ +     S ES   T +      +SK +  EE  EE  +E 
Sbjct: 296  QKDLASGAVPTNLKPSKIKQR---ADSKESLKATTKTA----VSKLAKREEVVEEGAKEA 348

Query: 1082 EEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQSVAIKRKRPFVLKKKRGRKRRRIN 1141
              E  +E  + E++ +E  E+     + P R+    S A+K ++  ++K K G+K  +  
Sbjct: 349  RSELAKELAKTEKKAKESSEKPPEKPAKPERVKTESSEALKAEKRKLIKDKVGKKHLKEK 408

Query: 1142 SSVTTETISETTEVLNEPFDNSDEERPMPQLEPTCEIEVEEDGRKPVLRKAFQHQPGKKR 1201
             S   E   +  + + +      ++    + +   + E +    KP L+K    +P  K 
Sbjct: 409  ISKLEEKKDKEKKEIKKERKELKKDEGRKEEKKDAKKEEKRKDTKPELKKI--SKPDLKP 466

Query: 1202 QTEEEEGKDNHCFKNADPCRNNMNDDSS--NLKEGSKDNPEPLKCKQVWPKGTKRGLSKW 1259
             T E        +K   P R  ++   +    KE S +   P   K   P  T  G    
Sbjct: 467  FTPEVR---KTLYKAKVPGRVKIDRSRAIRGEKELSSEPQTPPAQKGTVPLPTISG---- 519

Query: 1260 RQNKERKTGFKLNLYTPPETPMEPDEQVTVEEQKETSEGKTSPSPIRIEEEVKETGEALL 1319
              ++E       +L T     M+ +E+  + EQ++T  G   P P+   EE   +     
Sbjct: 520  --HRELVLSSPEDL-TQDFEEMKREERALLAEQRDTGLGD-KPFPLDTAEEGPPS----- 570

Query: 1320 PQEENRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEE-----------EEEEEEE 1368
                     T    +P + PG   E+ ++K +E   E  EE+           E EEE++
Sbjct: 571  ---------TAIQGTPPSVPGLGQEEHVMKEKELVPEVPEEQGSKDRGLDSGAETEEEKD 621

Query: 1369 GEEEEGGGNVEKDPDGAKSQEKEEPEISTEKEDSARLDDHEEEEEEDEEPSHNEDHDADD 1428
              EE+     E+ PD  +++E+ EPE+   KED   ++  E EE E+  PS  E+ DA  
Sbjct: 622  TWEEKKQREAERLPDRTEAREESEPEV---KEDV--IEKAELEEMEEVHPSDEEEEDATK 676

Query: 1429 EDDSHMESAEVEKEELP--RESF-------KEVLENQETFLDLNVQPGHSNPEVLMDCGV 1479
             +  + +  +   +  P  RE+F       +     +ET L L+     +     +    
Sbjct: 677  AEGFYQKHMQEPLKVTPRSREAFGGRELGLQGKAPEKETSLFLSSLTTPAGATEHVSYIQ 736

Query: 1480 DLTASCNSEPKELAGDPEAVPESDEEPPPGEQAQKQDQKNSKEVDTEFKEGNPATMEIDS 1539
            D T    SE ++   D E   E +E P P             E    F+   PA   + +
Sbjct: 737  DETIPGYSETEQTISDEEIHDEPEERPAPPRFHTSTYDLPGPEGAGPFEASQPADSAVPA 796

Query: 1540 ETVQAVQSLTQESSEQDDTFQDCAETQEACRSLQNYTRADQSPQIATTLDDCQQSDHSSP 1599
             + +   +   E +   +        +E   S  + T  D+    AT++ +         
Sbjct: 797  TSGKVYGTPETELTYPTNIVAAPLAEEEHVSSATSITECDKLSSFATSVAE--------- 847

Query: 1600 VSSVHSHPGQSVRSVNSPSVPALENSYAQISPDQSAISVPSLQNMETSPMMDVPS---VS 1656
                     QSV S+ +P       S   +    +  S+PS +   T  +  VPS   +S
Sbjct: 848  --------DQSVASLTAPQTEETGKSSLLL---DTVTSIPSSRTEATQGLDYVPSAGTIS 896

Query: 1657 DHSQQVVDSGF 1667
              S    D GF
Sbjct: 897  PTSSLEEDKGF 907



 Score = 67.0 bits (162), Expect = 2e-10
 Identities = 105/485 (21%), Positives = 188/485 (38%), Gaps = 84/485 (17%)

Query: 988  TPILISNAAVSEE--EREAEKEAERLMEQASCWEKEEQEILSTRANSRQSPAKVQSKNKY 1045
            T   +S  A  EE  E  A++    L ++ +  EK+ +E           P +V++++  
Sbjct: 327  TKTAVSKLAKREEVVEEGAKEARSELAKELAKTEKKAKESSEKPPEKPAKPERVKTESSE 386

Query: 1046 LHSPESRPVTGERGQLLELSKESSEEEEEEEDEEEE--EEEEEEEEDEEEEEEEEEEEEE 1103
                E R +  ++     L ++ S+ EE+++ E++E  +E +E ++DE  +EE+++ ++E
Sbjct: 387  ALKAEKRKLIKDKVGKKHLKEKISKLEEKKDKEKKEIKKERKELKKDEGRKEEKKDAKKE 446

Query: 1104 ENIQSSPPRLTKPQSVAIKRKRPFVLKKKRGRKRRRINSSVTTETISETTEVLNEPFDNS 1163
            E  + + P L K     +K   PF  + ++   + ++   V    I  +  +  E   +S
Sbjct: 447  EKRKDTKPELKKISKPDLK---PFTPEVRKTLYKAKVPGRV---KIDRSRAIRGEKELSS 500

Query: 1164 DEERPMPQLEPTCEIEVEEDGRKPVLRKAFQHQPGKKRQTEEEEGKDNHCFKNADPCRNN 1223
            + + P P  + T  +      R+ VL       P    Q  EE  ++             
Sbjct: 501  EPQTP-PAQKGTVPLPTISGHRELVL-----SSPEDLTQDFEEMKREERALL-------- 546

Query: 1224 MNDDSSNLKEGSKDNPEPLKCKQVWPKGTK-RGLSKWRQNKERKTGFKLNLYTPPETP-- 1280
                +     G  D P PL   +  P  T  +G                   TPP  P  
Sbjct: 547  ----AEQRDTGLGDKPFPLDTAEEGPPSTAIQG-------------------TPPSVPGL 583

Query: 1281 ------MEPDEQVTVEEQKETSEGKTSPSPIRIEEEVKETGEALLPQEENRREETCAPVS 1334
                  M+  E V    +++ S+ +   S    EEE K+T E     E+ +RE    P  
Sbjct: 584  GQEEHVMKEKELVPEVPEEQGSKDRGLDSGAETEEE-KDTWE-----EKKQREAERLPDR 637

Query: 1335 PNTSPGEKPE--DDLIKPEEEEEEEEEEEEEEEEEEGEEEEG------------------ 1374
                   +PE  +D+I+  E EE EE    +EEEE+  + EG                  
Sbjct: 638  TEAREESEPEVKEDVIEKAELEEMEEVHPSDEEEEDATKAEGFYQKHMQEPLKVTPRSRE 697

Query: 1375 -GGNVEKDPDGAKSQEKEEPEISTEKEDSARLDDHEEEEEEDEEPSHNEDHDADDEDDSH 1433
              G  E    G K+ EKE     +     A   +H    +++  P ++E      +++ H
Sbjct: 698  AFGGRELGLQG-KAPEKETSLFLSSLTTPAGATEHVSYIQDETIPGYSETEQTISDEEIH 756

Query: 1434 MESAE 1438
             E  E
Sbjct: 757  DEPEE 761



 Score = 48.9 bits (115), Expect = 5e-05
 Identities = 57/300 (19%), Positives = 126/300 (42%), Gaps = 33/300 (11%)

Query: 1277 PETPMEPDEQVTVEEQKETSEGKTSPSPIRIEEEVKETGEALLPQEENRREETCAPVSPN 1336
            P     PDE +   +   +   ++ P P    E++    E  +P  ++R  E      P 
Sbjct: 1306 PGAITSPDEHILTPDSSFSKSPESLPGPAL--EDIAIKWEDKVPGLKDRTSEQKKEPEPK 1363

Query: 1337 TSPGEKPEDDL-----IKPEEEEEEEEEE------EEEEEEEEGEEEEGGGNVEKDPDGA 1385
                ++ +  L     ++P++    +++E      E  +++++  E++G    +KD    
Sbjct: 1364 DEVLQQKDKTLEHKEVVEPKDTAIYQKDEALHVKNEAVKQQDKALEQKGRDLEQKDTALE 1423

Query: 1386 KSQEKEEPEISTEKEDSARLDDHEEEEEEDEEPSHNEDHDADDEDDS-HMESAEVEKEEL 1444
            +  +  EP+    +E    L+  ++  EE ++    +D   + +D +   +  ++E+++ 
Sbjct: 1424 QKDKALEPKDKDLEEKDKALEQKDKIPEEKDKALEQKDTALEQKDKALEPKDKDLEQKDR 1483

Query: 1445 PRESFKEVLENQETFLDLNVQP-GHSNPEVLMDCGVDLTASCNSEPKELAGDPEAVPESD 1503
              E  +++ E ++  LD  V+   H  PE       D  A       E         ++D
Sbjct: 1484 VLEQKEKIPEEKDKALDQKVRSVEHKAPE-------DTVAEMKDRDLE---------QTD 1527

Query: 1504 EEPPPGEQAQKQDQKNSKEVDTEFKEGNPATMEIDSETVQAVQSLTQ--ESSEQDDTFQD 1561
            + P    QAQ+Q  K S++ D   ++   A  + D    Q +Q+L +  ++ EQ+   Q+
Sbjct: 1528 KAPEQKHQAQEQKDKVSEKKDQALEQKYWALGQKDEALEQNIQALEENHQTQEQESLVQE 1587



 Score = 43.9 bits (102), Expect = 0.002
 Identities = 100/497 (20%), Positives = 191/497 (38%), Gaps = 106/497 (21%)

Query: 996  AVSEEEREAEKEAERLMEQASCWEKEEQEILSTRANSRQSPAK----VQSKNKYLHSPES 1051
            A+  ++++ E++ +R++EQ     +E+ + L  +  S +  A      + K++ L   + 
Sbjct: 1470 ALEPKDKDLEQK-DRVLEQKEKIPEEKDKALDQKVRSVEHKAPEDTVAEMKDRDLEQTDK 1528

Query: 1052 RPVTGERGQLLELSKESSEEEEEEEDEEE----EEEEEEEEEDEEEEEEEEEEEEEENIQ 1107
             P   ++ Q  E   + SE++++  +++     +++E  E+  +  EE  + +E+E  +Q
Sbjct: 1529 APE--QKHQAQEQKDKVSEKKDQALEQKYWALGQKDEALEQNIQALEENHQTQEQESLVQ 1586

Query: 1108 SSPPRLTK------PQSV-AIKRKRPFVLKKKR-----------GRKRRRINSSVTTETI 1149
                R  K      P+ V A++ K   +L+K +           GR R +       + +
Sbjct: 1587 EDKTRKPKMLEEKSPEKVKAMEEKLEALLEKTKALGLEESLVQEGRAREQEEKYWRGQDV 1646

Query: 1150 ----SETTEVLNEPFDNSDEERPM-----PQLEPTC-----EIEVEEDG--------RKP 1187
                 ET+    EP     E  P      P+ +        ++ +E+D         RK 
Sbjct: 1647 VQEWQETSPTREEPAGEQKELAPAWEDTSPEQDNRYWRGREDVALEQDTYWRELSCERKV 1706

Query: 1188 VLRKAFQHQPGKKRQTEE------EEGKDNHCFKNADPCRNNMNDD--SSNLKEGSKDNP 1239
                    Q  +   TEE      +EG D+   +   P R +      +S+ K+  + +P
Sbjct: 1707 WFPHELDGQGARPHYTEERESTFLDEGPDD---EQEVPLREHATRSPWASDFKDFQESSP 1763

Query: 1240 EPLKCKQVWPKGTKRGLSKWRQNKERKTGFKLNLYTPPETPMEPDEQVTVEEQKETSEGK 1299
            +     + W   +  GL    ++K  ++ F++   +PP +P E      V ++  ++ G+
Sbjct: 1764 QKGLEVERWLAESPVGLPPEEEDKLTRSPFEI--ISPPASPPE-----MVGQRVPSAPGQ 1816

Query: 1300 TSPSP-------IRIEEEVKETGEALLPQEENRREETCAPVSPNTSP------------- 1339
             SP P       ++ E         + P     R    AP+SP   P             
Sbjct: 1817 ESPIPDPKLMPHMKNEPTTPSWLADIPPWVPKDRPLPPAPLSPAPGPPTPAPESHTPAPF 1876

Query: 1340 --GEKPEDDLIKPEEEEEEEEE--------------EEEEEEEEEGEEEEGGGNVEKDPD 1383
              G    D ++   +E   E E              E E EEE   E  +   +  K P+
Sbjct: 1877 SWGTAEYDSVVAAVQEGAAELEGGPYSPLGKDYRKAEGEREEEGRAEAPDKSSHSSKVPE 1936

Query: 1384 GAKSQEKEEPEISTEKE 1400
             +KS    EPE  TE E
Sbjct: 1937 ASKSHATTEPE-QTEPE 1952



 Score = 38.1 bits (87), Expect = 0.090
 Identities = 68/348 (19%), Positives = 142/348 (40%), Gaps = 40/348 (11%)

Query: 998  SEEEREAEKEAERLMEQASCWE-KEEQEILSTRANSRQSPAKVQSKNKYLHSPESRPVTG 1056
            SE+++E E + E L ++    E KE  E   T    +     V  KN+ +   +      
Sbjct: 1354 SEQKKEPEPKDEVLQQKDKTLEHKEVVEPKDTAIYQKDEALHV--KNEAVKQQDK--ALE 1409

Query: 1057 ERGQLLELSKESSEEEE---EEEDEE-EEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPR 1112
            ++G+ LE    + E+++   E +D++ EE+++  E++D+  EE+++  E+++       +
Sbjct: 1410 QKGRDLEQKDTALEQKDKALEPKDKDLEEKDKALEQKDKIPEEKDKALEQKDTALEQKDK 1469

Query: 1113 LTKPQSVAIKRKRPFVLKKKR---------GRKRRRINSSVTTETISETTEVLNEPFDNS 1163
              +P+   +++K   + +K++          +K R +      +T++E  +   E  D +
Sbjct: 1470 ALEPKDKDLEQKDRVLEQKEKIPEEKDKALDQKVRSVEHKAPEDTVAEMKDRDLEQTDKA 1529

Query: 1164 DEERPMPQLEPTCEIEVEEDGRKPVLRKAFQHQPGKKRQTEEEEGKDNHCFKNADPCRNN 1223
             E++   Q +     E ++   +       Q     ++  +  E  +NH           
Sbjct: 1530 PEQKHQAQEQKDKVSEKKDQALEQKYWALGQKDEALEQNIQALE--ENH----------Q 1577

Query: 1224 MNDDSSNLKEGSKDNPEPLKCKQVWPKGTKRGLSKWRQNKERKTGFKLNLYTPPETPMEP 1283
              +  S ++E     P+ L+ K   P+  K    K     E+     L      E     
Sbjct: 1578 TQEQESLVQEDKTRKPKMLEEKS--PEKVKAMEEKLEALLEKTKALGLEESLVQEGRARE 1635

Query: 1284 DE------QVTVEEQKETSEGKTSPSPIRIEEEVKETGEALLPQEENR 1325
             E      Q  V+E +ETS   T   P   ++E+    E   P+++NR
Sbjct: 1636 QEEKYWRGQDVVQEWQETS--PTREEPAGEQKELAPAWEDTSPEQDNR 1681



 Score = 34.7 bits (78), Expect = 1.00
 Identities = 140/693 (20%), Positives = 260/693 (37%), Gaps = 111/693 (16%)

Query: 1044 KYLHSPESRPVTGERGQLLELSKESSEEEEEEEDEEEEEEEEE-------EEEDEEEEEE 1096
            +YLH      V+ E  Q L LS+ES  +E   +   ++   E        E    +EE  
Sbjct: 1179 QYLHKDRWPEVSPEDTQSLSLSEESPSKETSLDVSSKQLSPESLGTLQFGELNLGKEEMG 1238

Query: 1097 EEEEEEEENIQSSPPRLTKPQSVAIK---------RKRPFVLKKKRGRKRRRINSSVTTE 1147
               + E+ +  ++P  + +P +               +  +      RK    + S +T 
Sbjct: 1239 HLMQAEDTSHHTAPMSVPEPHAATASPPTDGTTRYSAQTDITDDSLDRKSPASSFSHSTP 1298

Query: 1148 T---------ISETTEVLNEP---FDNSDEERPMPQLEPTCEIEVEEDGRKPVLRKAFQH 1195
            +         I+   E +  P   F  S E  P P LE   +I ++ + + P L+     
Sbjct: 1299 SGNGKYLPGAITSPDEHILTPDSSFSKSPESLPGPALE---DIAIKWEDKVPGLKDR--- 1352

Query: 1196 QPGKKRQTEEEEGKDNHCFKNADPCRNNMNDDSSNLKEGSKDNPEPLKCKQVWPKGTKRG 1255
                  Q +E E KD    +      +    +  +     KD  E L  K    K   + 
Sbjct: 1353 ---TSEQKKEPEPKDEVLQQKDKTLEHKEVVEPKDTAIYQKD--EALHVKNEAVKQQDKA 1407

Query: 1256 LS-KWRQNKERKTGF--KLNLYTPPETPME------------PDEQVTVEEQKETSEGKT 1300
            L  K R  +++ T    K     P +  +E            P+E+    EQK+T+  + 
Sbjct: 1408 LEQKGRDLEQKDTALEQKDKALEPKDKDLEEKDKALEQKDKIPEEKDKALEQKDTALEQK 1467

Query: 1301 SPSPIRIEEEVKETGEALLPQEENRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEE 1360
              +    ++++++    L  +E+   E+  A      S   K  +D +   ++ + E+ +
Sbjct: 1468 DKALEPKDKDLEQKDRVLEQKEKIPEEKDKALDQKVRSVEHKAPEDTVAEMKDRDLEQTD 1527

Query: 1361 EEEEEEEEGEEEEGGGNVEKDPDGAKSQEKEEPEISTEKEDSARLDDHEEEEEEDEEPSH 1420
            +  E++ + +E++   + +KD      Q  E+   +  ++D A L+ + +  EE+ +   
Sbjct: 1528 KAPEQKHQAQEQKDKVSEKKD------QALEQKYWALGQKDEA-LEQNIQALEENHQTQE 1580

Query: 1421 NEDHDADDE--DDSHMESAEVEKEELPRESFKEVLENQET--FLDLNVQPGHS-NPEVLM 1475
             E    +D+      +E    EK +   E  + +LE  +     +  VQ G +   E   
Sbjct: 1581 QESLVQEDKTRKPKMLEEKSPEKVKAMEEKLEALLEKTKALGLEESLVQEGRAREQEEKY 1640

Query: 1476 DCGVDL------TASCNSEP----KELA-GDPEAVPESDEEPPPGEQAQKQDQKNS-KEV 1523
              G D+      T+    EP    KELA    +  PE D     G +    +Q    +E+
Sbjct: 1641 WRGQDVVQEWQETSPTREEPAGEQKELAPAWEDTSPEQDNRYWRGREDVALEQDTYWREL 1700

Query: 1524 DTEFKEGNPATMEIDSETVQAVQSLTQESSEQDDTFQDCAETQEACRSLQNYTRADQSPQ 1583
              E K   P   E+D +  +        + E++ TF D     E    L+ +  A +SP 
Sbjct: 1701 SCERKVWFP--HELDGQGAR-----PHYTEERESTFLDEGPDDEQEVPLREH--ATRSPW 1751

Query: 1584 IATTLDDCQQSD-----------HSSPVSSVHSHPGQSVRS----VNSPSVP------AL 1622
             A+   D Q+S              SPV        +  RS    ++ P+ P       +
Sbjct: 1752 -ASDFKDFQESSPQKGLEVERWLAESPVGLPPEEEDKLTRSPFEIISPPASPPEMVGQRV 1810

Query: 1623 ENSYAQISPDQSAISVPSLQNMETSP--MMDVP 1653
             ++  Q SP      +P ++N  T+P  + D+P
Sbjct: 1811 PSAPGQESPIPDPKLMPHMKNEPTTPSWLADIP 1843


>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
          Length = 843

 Score = 81.6 bits (200), Expect = 7e-15
 Identities = 102/476 (21%), Positives = 182/476 (38%), Gaps = 66/476 (13%)

Query: 1000 EEREAEKEAERLMEQASCWEKEEQEILSTRANSRQSPAKVQSKNKYLHSPESRPVTGERG 1059
            E RE E+E ER  E+    EKE +       +  ++  + + +++       R  + +R 
Sbjct: 321  ERREREREREREREREK--EKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRN 378

Query: 1060 QLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQSV 1119
            +    S+E S + E E + E E E E E E E E E E E E E   +            
Sbjct: 379  KDRSRSREKSRDREREREREREREREREREREREREREREREREREREKD---------- 428

Query: 1120 AIKRKRPFVLKKKRGRKRRRINSSVTTETISETTEVLNEPFDNSDEERPMPQLEPTCEIE 1179
               +KR     ++   +RR++        + E      E   N +        E   E E
Sbjct: 429  ---KKRDREEDEEDAYERRKLE-----RKLREKEAAYQERLKNWEIRERKKTREYEKEAE 480

Query: 1180 VEEDGRKPVLRKAFQHQPGKKRQTEEEEGKDNHCFKNADPCRNNMNDDSSNLKEGSKDNP 1239
             EE+ R+ + ++A   +  K+   + ++ +D+  +      +  + D    ++   +D  
Sbjct: 481  REEERRREMAKEA---KRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREKEMEADERDRK 537

Query: 1240 -EPLKCKQVWPKGTKRG-------LSKWRQNKERKTGFKLNLYTPPETPMEPDEQVTVEE 1291
             E  + +++  +    G       L +  Q  ER+          P+   EP+ +   EE
Sbjct: 538  REKEELEEIRQRLLAEGHPDPDAELQRMEQEAERR--------RQPQIKQEPESEEEEEE 589

Query: 1292 QKETSEGKTSPSPIRIEEEVKETGEALLPQEENRREETCAP--------VSPNTSPGEKP 1343
            ++E  E +  P     EEE  E    L P     R  + AP         +PNT PG++ 
Sbjct: 590  KQEKEEKREEPME---EEEEPEQKPCLKP---TLRPISSAPSVSSASGNATPNT-PGDES 642

Query: 1344 EDDLIKPEEEEEEEEEEEEEEEEEEGEEEEGGGNVEKDPDGAKSQEKEEPEISTEKEDSA 1403
               +I P E   ++++ EE   +     + G  N    P+  K ++     +  + ED  
Sbjct: 643  PCGIIIPHENSPDQQQPEEHRPKIGLSLKLGASNSPGQPNSVKRKKLPVDSVFNKFED-- 700

Query: 1404 RLDDHEEEEEEDEEPSHNEDHDAD-DEDDSHMESAEVEKEELPRESFKEVLENQET 1458
                    E+ D+ P   +    D  EDD +     V  EE  R+  K ++E   T
Sbjct: 701  --------EDSDDVPRKRKLVPLDYGEDDKNATKGTVNTEE-KRKHIKSLIEKIPT 747



 Score = 66.2 bits (160), Expect = 3e-10
 Identities = 87/408 (21%), Positives = 159/408 (38%), Gaps = 67/408 (16%)

Query: 1020 KEEQEILSTRANSRQSPAKVQSKNKYLHSPESRPVTGERGQLLELSKESSEEEEEEEDEE 1079
            KE+   +    + R   ++  SK +  H    + +  E+G+     KE  E E+E  + E
Sbjct: 261  KEDINAIEMEEDKRDLISREISKFRDTH----KKLEEEKGKK---EKERQEIEKERRERE 313

Query: 1080 EEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQSVAIKRKRPFVLKKKRGRKRRR 1139
             E E E E  + E E E E E E+E  +       + +    +R R     ++R R R R
Sbjct: 314  RERERERERREREREREREREREKEKERERERERDRDRDRTKERDRD--RDRERDRDRDR 371

Query: 1140 INSSVTTETISETTEVLNEPFDNSDEERPMPQLEPTCEIEVEEDGRKPVLRKAFQHQPGK 1199
              SS   +  S + E       + D ER         E E E +  +       + +  +
Sbjct: 372  ERSSDRNKDRSRSRE------KSRDRER---------ERERERERER-------ERERER 409

Query: 1200 KRQTEEEEGKDNHCFKNADPCRNNMNDDSSNLKEGSKDNPEPLKCKQVWPKGTKRGLSKW 1259
            +R+ E E  ++    +  D  R+   D+    +    +    L+ K+      +  L  W
Sbjct: 410  EREREREREREREREREKDKKRDREEDEEDAYERRKLE--RKLREKEA---AYQERLKNW 464

Query: 1260 RQNKERKTGFKLNLYTPPETPMEPDEQVTVEEQKETSEGKTSPSPIRIEEEVKETGEALL 1319
               + +KT              E +++   EE++     K          E K   E L 
Sbjct: 465  EIRERKKT-------------REYEKEAEREEERRREMAK----------EAKRLKEFLE 501

Query: 1320 PQEENRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGEEEEGGGNVE 1379
              +++R +    P     S  +K   D  K  E +E + + E+EE EE  +     G+ +
Sbjct: 502  DYDDDRDD----PKYYRGSALQKRLRDREKEMEADERDRKREKEELEEIRQRLLAEGHPD 557

Query: 1380 KDPD----GAKSQEKEEPEISTEKEDSARLDDHEEEEEEDEEPSHNED 1423
             D +      +++ + +P+I  E E     ++ +E+EE+ EEP   E+
Sbjct: 558  PDAELQRMEQEAERRRQPQIKQEPESEEEEEEKQEKEEKREEPMEEEE 605



 Score = 56.6 bits (135), Expect = 2e-07
 Identities = 107/588 (18%), Positives = 217/588 (36%), Gaps = 82/588 (13%)

Query: 1056 GERGQLLELSKESSEEEEEEEDEEEEEEEEEEEE----DEEEEEEEEEEEEEENIQSSPP 1111
            GE+  L+++  ++  + +E + +++        E    D+EE  +EE +  ++ I+ +  
Sbjct: 153  GEKKLLVKVDAKTKAQLDEWKAKKKASNGNARPETVTNDDEEALDEETKRRDQMIKGAIE 212

Query: 1112 RLTKPQSVAIKRKRPFVLKKKRGRKRRRINSSVTTETISETTEVLNEPFDNSDEERPMPQ 1171
             L +  S  +           R +K+ +         ++        P+       P+  
Sbjct: 213  VLIREYSSELNAPSQESDSHPRKKKKEKKEDIFRRFPVAPLI-----PY-------PLIT 260

Query: 1172 LEPTCEIEVEEDGRKPVLRKAFQHQPGKKRQTEEEEGKDNHCFKNADPCRNNMNDDSSNL 1231
             E    IE+EED R  + R+  + +   K+  EEE+GK     +  +  R     +    
Sbjct: 261  KEDINAIEMEEDKRDLISREISKFRDTHKK-LEEEKGKKEKERQEIEKERRERERERERE 319

Query: 1232 KEGSKDNPEPLKCKQVWPKGTKRGLSKWRQNKERKTGFKLNLYTPPETPMEPDEQVTVEE 1291
            +E  +   E  + ++   +  K    +  ++++R    + +     E   + D + + + 
Sbjct: 320  RERRERERERERERE--REKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDR 377

Query: 1292 QKETSEGKTSPSPIRIEEEVKETGEALLPQEENRREETCAPVSPNTSPGEKPEDDLIKPE 1351
             K+ S  +      R  E  +E       + E  RE             E+  +   + E
Sbjct: 378  NKDRSRSREKS---RDRERERERERERERERERERER------------ERERERERERE 422

Query: 1352 EEEEEEEEEEEEEEEEEGEEEEGGGNVEKDPDGAKSQEKEEPEISTEKEDSARLDDHEEE 1411
             E E++++ + EE+EE+  E        ++ + A  +  +  EI   K+      + E E
Sbjct: 423  REREKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAERE 482

Query: 1412 EEEDEEPSHN--------EDHDADDEDDSHMESA-----------EVEKEELPRESFKEV 1452
            EE   E +          ED+D D +D  +   +           E+E +E  R+  KE 
Sbjct: 483  EERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREKEMEADERDRKREKEE 542

Query: 1453 LENQETFLDLNVQPGHSNPEVLMDCGVDLTASCNSEPKELAGDPEAVPESDEEPPPGEQA 1512
            LE     L   +  GH +P+  +            +  E   +    P+  +EP   E+ 
Sbjct: 543  LEEIRQRL---LAEGHPDPDAEL------------QRMEQEAERRRQPQIKQEPESEEEE 587

Query: 1513 QKQDQKNSKEVDTEFKEGNPATMEIDSETVQAVQSLTQESSEQDDTFQDCAETQEACRSL 1572
            +++ +K  K  +   +E  P        T++ + S    SS   +   +    +  C  +
Sbjct: 588  EEKQEKEEKREEPMEEEEEPEQKPCLKPTLRPISSAPSVSSASGNATPNTPGDESPCGII 647

Query: 1573 QNYTRADQSPQIATTLDDCQQSDHSSPVSSVHSHPGQSVRSVNSPSVP 1620
              +   + SP       D QQ +   P   +    G S    NSP  P
Sbjct: 648  IPH---ENSP-------DQQQPEEHRPKIGLSLKLGAS----NSPGQP 681


>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
           sapiens]
          Length = 5537

 Score = 81.6 bits (200), Expect = 7e-15
 Identities = 40/103 (38%), Positives = 50/103 (48%), Gaps = 10/103 (9%)

Query: 216 CSFCLGTKESNREKKPEELLSCADCGSSGHPSCLKFCPELTTNVKALRWQCIECKTCSAC 275
           C+ C G  E        +L  C  CG   H +CL       T  K   WQC ECK C AC
Sbjct: 229 CAVCEGPGELC------DLFFCTSCGHHYHGACLDTA---LTARKRAGWQCPECKVCQAC 279

Query: 276 RVQGRNADNMLFCDSCDRGFHMECCDPPLSRMPKGMWICQVCR 318
           R  G N   ML C++CD+G+H  C  PP+  +P   W C+ CR
Sbjct: 280 RKPG-NDSKMLVCETCDKGYHTFCLKPPMEELPAHSWKCKACR 321



 Score = 75.5 bits (184), Expect = 5e-13
 Identities = 34/85 (40%), Positives = 45/85 (52%), Gaps = 5/85 (5%)

Query: 234  LLSCADCGSSGHPSCLKFCPELTTNVKALR-WQCIECKTCSACRVQGRNADNMLFCDSCD 292
            LL+C+ C    HP C+       T V  L+ W+C+EC  C  C  Q  +   +L CD CD
Sbjct: 1394 LLACSQCSQCYHPYCVN---SKITKVMLLKGWRCVECIVCEVCG-QASDPSRLLLCDDCD 1449

Query: 293  RGFHMECCDPPLSRMPKGMWICQVC 317
              +H  C DPPL  +PKG W C+ C
Sbjct: 1450 ISYHTYCLDPPLLTVPKGGWKCKWC 1474



 Score = 39.3 bits (90), Expect = 0.040
 Identities = 24/82 (29%), Positives = 32/82 (39%), Gaps = 12/82 (14%)

Query: 252 CPELTTNVKALRWQCIECKTCSACRVQGRNADNMLFCDSCDRGFHMECCDPPLSRMPKGM 311
           CPE +     L     E   C+ C   G   D + FC SC   +H  C D  L+   +  
Sbjct: 214 CPEHSEGAAYL-----EEARCAVCEGPGELCD-LFFCTSCGHHYHGACLDTALTARKRAG 267

Query: 312 W------ICQVCRPKKKGRKLL 327
           W      +CQ CR      K+L
Sbjct: 268 WQCPECKVCQACRKPGNDSKML 289



 Score = 37.0 bits (84), Expect = 0.20
 Identities = 21/60 (35%), Positives = 26/60 (43%), Gaps = 3/60 (5%)

Query: 216  CSFCLGTKESNREKKPEELLSCADCGSSGHPSCLKFCPELTTNVKALRWQCIECKTCSAC 275
            C  C+  +   +   P  LL C DC  S H  CL   P L T  K   W+C  C +C  C
Sbjct: 1424 CVECIVCEVCGQASDPSRLLLCDDCDISYHTYCLD--PPLLTVPKG-GWKCKWCVSCMQC 1480



 Score = 36.6 bits (83), Expect = 0.26
 Identities = 19/62 (30%), Positives = 26/62 (41%), Gaps = 6/62 (9%)

Query: 214 PICSFCLGTKESNREKKPEELLSCADCGSSGHPSCLKFCPELTTNVKALRWQCIECKTCS 273
           P C  C   ++   + K   +L C  C    H  CLK   E    + A  W+C  C+ C 
Sbjct: 271 PECKVCQACRKPGNDSK---MLVCETCDKGYHTFCLKPPME---ELPAHSWKCKACRVCR 324

Query: 274 AC 275
           AC
Sbjct: 325 AC 326



 Score = 34.3 bits (77), Expect = 1.3
 Identities = 81/396 (20%), Positives = 138/396 (34%), Gaps = 54/396 (13%)

Query: 1274 YTPPE---TPMEPDEQVTVEEQKETSEGKTS------PSPIRIEEE-VKETGEALLPQEE 1323
            ++PPE   TP +  + + V  Q +   G  +      P P++ E + + + G  L PQ E
Sbjct: 372  FSPPEPGDTPTDEPDALYVACQGQPKGGHVTSMQPKEPGPLQCEAKPLGKAGVQLEPQLE 431

Query: 1324 NRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGEEEEGGGNVEKDPD 1383
                   AP++        PE+  + P  EE       E        EE     +   P+
Sbjct: 432  -------APLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPL---PE 481

Query: 1384 GAK-SQEKEEPEISTEKEDSARLDDHEEEEEEDEEPSHNEDHDADDEDDSHMESAEVEKE 1442
                S+  EE  +S   E+S      E       E S     +         ES      
Sbjct: 482  ALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPE---------ESPPSPAL 532

Query: 1443 ELPRESFKEVLENQETFLDLNVQPGHSNPEVLMDCGVDLTASCNSEPKELAGDPEAVPES 1502
            E P     E       F +  + P    PE       +L  S   E   L+  PE  P S
Sbjct: 533  ETPLSPPPEASPLSPPFEESPLSPP---PE-------ELPTSPPPEASRLSPPPEESPMS 582

Query: 1503 DEEPPPGEQAQKQDQKNSKEVDTEFKEGNPATMEIDSETVQAVQSLTQESSEQDDTFQDC 1562
                PP E++       +  +   F+E +P +   +   +      ++ S   +D+    
Sbjct: 583  ----PPPEESPMSPPPEASRLFPPFEE-SPLSPPPEESPLSPPPEASRLSPPPEDSPMSP 637

Query: 1563 AETQEACRSLQNYTRADQSPQIATTLDDCQQSDHSSPVSSVHSHPGQSVRSVN-----SP 1617
               +         +R    P ++      ++S  S P     + P      ++     SP
Sbjct: 638  PPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSP 697

Query: 1618 SVPALENSYAQISPDQSAISVPSLQNMETSPMMDVP 1653
            + P  E+S A   P+ S +S+P    +E SP++ +P
Sbjct: 698  TSPPPEDSPASPPPEDSLMSLP----LEESPLLPLP 729



 Score = 32.0 bits (71), Expect = 6.5
 Identities = 22/69 (31%), Positives = 31/69 (44%), Gaps = 3/69 (4%)

Query: 1853 LSNTGLVQLSQSPHSVPGGPQAQATMTPPPNLTPPPMNLPPPLLQRNMAASNIGISHSQR 1912
            LS  G   LS  P  +P  P  + +++P      PP  LPPPL     AA+   +S    
Sbjct: 900  LSEPGEPPLSPLPEELPLSPSGEPSLSPQ---LMPPDPLPPPLSPIITAAAPPALSPLGE 956

Query: 1913 LQTQIASKG 1921
            L+    +KG
Sbjct: 957  LEYPFGAKG 965


>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
            protein 6 [Homo sapiens]
          Length = 724

 Score = 80.9 bits (198), Expect = 1e-14
 Identities = 94/480 (19%), Positives = 207/480 (43%), Gaps = 61/480 (12%)

Query: 1001 EREAEKEAERLMEQASCWEKEEQEILSTRANSRQSPAKVQSKNKYLHSPESRPVTGERGQ 1060
            + E +++  +L E+    E E+ EI   + N ++   K++     L   + +      G+
Sbjct: 277  DEELKEKNAKLQEKLQLVESEKSEI---QLNVKELKRKLERAKLLLPQQQLQAEADHLGK 333

Query: 1061 LLE-----LSKESSEEE-------EEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQS 1108
             L+     L  +  E E       ++EE    +EE+ +E E++ +E+EE+  E+EE I+ 
Sbjct: 334  ELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIRE 393

Query: 1109 SPPRLTKPQSVA------IKRKRPFVLKKKRGRKRRRINSSVTTETISETTEVLNEPFDN 1162
               ++ + + +       ++R+   + +K+   +R+        E I E  E ++E    
Sbjct: 394  QEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKI 453

Query: 1163 SDEERPMPQLEPTCEIEVEEDGRKPVLRKA--FQHQPGKKRQTEEEEGKDNHCFKNADPC 1220
             ++E    + E   E E  ++    + R+    + Q  K R+ EE+  +        +  
Sbjct: 454  REQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKI 513

Query: 1221 RNNMNDDSSNLKEGSKDNPEPLKCKQVWPKGTKRGLSKWRQNKERKTGFKLNLYTPPETP 1280
            R    +     +E  +   +  + +++W     R   K  + +E+    +  ++   E  
Sbjct: 514  REE--EKRQEQEEMWRQEEKIREQEEIW-----RQKEKIHEQEEKIRKQEEKMWRQEEKM 566

Query: 1281 MEPDEQVTVEEQKETSEGKTSPSPIRIEEEVKETGEALLPQEENRREETCAPVSPNTSPG 1340
             + +E++  +E+K            R EE+++E  E +  QEE  RE+            
Sbjct: 567  HDQEEKIREQEEKVW----------RQEEKIREQEEKIREQEEKIREQ------------ 604

Query: 1341 EKPEDDLIKPEEEEEEEEEEEEEEEEEEGEEEEGGGNVEKDPDGAKSQEK---EEPEIST 1397
                +++ + +EE+  E+EE+  E+EE+ +E+E    + +  +  + QEK   E+ E   
Sbjct: 605  ----EEMTQEQEEKMGEQEEKMCEQEEKMQEQE--EKMRRQEEKIREQEKKIREQEEKIR 658

Query: 1398 EKEDSARLDDHEEEEEEDEEPSHNEDHDADDEDDSHMESAEVEKEELPRESFKEVLENQE 1457
            E+E+  +  + +  E+E++     E     +E     E    E+E   R+  +++ E+QE
Sbjct: 659  EQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQE 718



 Score = 73.9 bits (180), Expect = 1e-12
 Identities = 95/428 (22%), Positives = 180/428 (42%), Gaps = 66/428 (15%)

Query: 994  NAAVSEEEREAEKEAERLMEQASCWEKEEQEILSTRANSRQSPAKVQSKNKYLHSPESRP 1053
            N    ++E +  ++ E++ E     +++E++I       R+   K++ + + +   E + 
Sbjct: 353  NRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKM 412

Query: 1054 VTGERGQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEE-EEEENIQSSPPR 1112
               E     +  K   +EE   E EE+  E EE+  ++E+  E+EE+ +EEE I+    R
Sbjct: 413  RRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKR 472

Query: 1113 LTKPQSVAIKRKRPFVLKKKRGRKRRRINSSVTTETISETTEVLNEPFDNSDEERPMPQL 1172
              + Q   + R+   + +++   + +        E I E  ++  E  +   E+  M + 
Sbjct: 473  --QEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREE--EKRQEQEEMWRQ 528

Query: 1173 EPTCEIEVEEDGRKPVLRKAFQHQPGKKRQTEEEEGKDNHCFKNADPCRNNMNDDSSNLK 1232
            E     E EE  R+   ++    Q  K R+ EE+  +              M+D    ++
Sbjct: 529  EEKIR-EQEEIWRQ---KEKIHEQEEKIRKQEEKMWRQ----------EEKMHDQEEKIR 574

Query: 1233 EGSKDNPEPLKCKQVWPKGTKRGLSKWRQNKERKTGFKLNLYTPPETPMEPDEQVTVEEQ 1292
            E           ++VW     R   K R+ +E+    +  +    E   E +E++  +E+
Sbjct: 575  EQE---------EKVW-----RQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEE 620

Query: 1293 KETSEGKTSPSPIRIEEEVKETGEALLPQEENRREETCAPVSPNTSPGEKPEDDLIKPEE 1352
            K   +          EE+++E  E +  QEE  RE+               E  + + EE
Sbjct: 621  KMCEQ----------EEKMQEQEEKMRRQEEKIREQ---------------EKKIREQEE 655

Query: 1353 EEEEEEEEEEEEEEEEGEEEEGGGNVEKDPDGAKSQEKEEPEISTEK---EDSARLDDHE 1409
            +  E+EE  +E+EE+  E+EE     E+     K QE+EE     E+   E   RL   E
Sbjct: 656  KIREQEEMMQEQEEKMWEQEEKMCEQEE-----KMQEQEEKMRRQEEKMWEQEVRLRQQE 710

Query: 1410 EEEEEDEE 1417
            E+ +E +E
Sbjct: 711  EKMQEHQE 718



 Score = 68.2 bits (165), Expect = 8e-11
 Identities = 119/584 (20%), Positives = 237/584 (40%), Gaps = 87/584 (14%)

Query: 958  IRREKLILSHMEKLKTCSRANELDPDSLRWTPILISNAAVSEEEREAEKEAERLMEQASC 1017
            +RRE     H  ++ TC +  EL         +  S  AV + E EA     RL +    
Sbjct: 182  LRRELEAQVHTIRILTCQKT-ELQ------MALYYSQHAVKQLEGEARDLISRLHDSWKF 234

Query: 1018 WEKEEQEILSTRANSRQSPAKVQSKNKYLHSPESRPVTGERGQL-LELSKESSEEEEEEE 1076
              + EQ + +     +++   ++             +T ER  L LEL + +  +EE +E
Sbjct: 235  AGELEQALSAVATQKKKADRYIEE------------LTKERDALSLELYRNTITDEELKE 282

Query: 1077 DEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQSVAIKRKRPFVLKKKRGRK 1136
               + +E+ +  E E+ E +   +E +  ++ +   L + Q  A             G++
Sbjct: 283  KNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQA--------EADHLGKE 334

Query: 1137 RRRINSSVTTETISETTEVLNEPFDNSDEERPMPQLEPTCEIEVEEDGRKPVLRKAFQHQ 1196
             + +++ +  +   E  E+ N   +   EE+   Q E   E E           +  Q Q
Sbjct: 335  LQSVSAKLQAQV--EENELWNR-LNQQQEEKMWRQEEKIQEWE-----------EKIQEQ 380

Query: 1197 PGKKRQTEEEEGKDNHCFKNADPCRNNMNDDSSNLKEGSKDNPEPLKCKQ--VWPKGTK- 1253
              K R+ EE+  +     +  +       +     +E   +  E ++ ++  +W K  K 
Sbjct: 381  EEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKI 440

Query: 1254 RGLSKWRQNKERKTGFKLNLYTPPETPMEPDEQVTVEEQKETSEGKTSPSPIRIEEEVKE 1313
            R L +    +E+            E   + +E++  +E+++  E K      R EE+++E
Sbjct: 441  RELEEKMHEQEK--------IREQEEKRQEEEKIREQEKRQEQEAKM----WRQEEKIRE 488

Query: 1314 TGEALLPQEEN--RREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGEE 1371
              E +  QEE   R+EE            +  E + I+ EEE+ +E+EE   +EE+  E+
Sbjct: 489  QEEKIREQEEKMWRQEE------------KIHEQEKIR-EEEKRQEQEEMWRQEEKIREQ 535

Query: 1372 EEGGGNVEKDPDGAKSQEKEEPEISTEKEDSARLDDHEEEEEEDEEPSHNEDHDADDEDD 1431
            EE     EK  +  +   K+E ++  ++E   ++ D EE+  E EE    ++    ++++
Sbjct: 536  EEIWRQKEKIHEQEEKIRKQEEKMWRQEE---KMHDQEEKIREQEEKVWRQEEKIREQEE 592

Query: 1432 SHMESAEV--EKEELPRESFKEVLENQETFLDLNVQPGHSNPEVLMDCGVDLTASCNSEP 1489
               E  E   E+EE+ +E  +++ E +E   +   +      ++              + 
Sbjct: 593  KIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQ-----EEKIREQE 647

Query: 1490 KELAGDPEAVPESDE-----EPPPGEQAQKQDQKNSKEVDTEFK 1528
            K++    E + E +E     E    EQ +K  ++  K  + E K
Sbjct: 648  KKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEK 691



 Score = 50.1 bits (118), Expect = 2e-05
 Identities = 84/444 (18%), Positives = 174/444 (39%), Gaps = 67/444 (15%)

Query: 1142 SSVTTETISETTEVLNEPFDNSDEERPMPQLEPTCEIEVEEDGRKPVLRKAFQHQPGKKR 1201
            +++T E + E    L E     + E+   QL       V+E  RK  L +A    P ++ 
Sbjct: 273  NTITDEELKEKNAKLQEKLQLVESEKSEIQLN------VKELKRK--LERAKLLLPQQQL 324

Query: 1202 QTEEEEGKDNHCFKNADPCRNNMNDDSSNLKEGSKDNPEPLKCKQVWPKGTKRGLSKWRQ 1261
            Q E            AD     +   S+ L+   ++N       ++W +  ++   K  +
Sbjct: 325  QAE------------ADHLGKELQSVSAKLQAQVEEN-------ELWNRLNQQQEEKMWR 365

Query: 1262 NKERKTGFKLNLYTPPETPMEPDEQVTVEEQKETSEGKTSPSPIRIEEEVKETGEALLPQ 1321
             +E+   ++  +    E   E +E++  +E+K            R EE + E  E +  Q
Sbjct: 366  QEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMR----------RQEEMMWEKEEKMRRQ 415

Query: 1322 EENRREETCAPVSPNTSPGEKPE-----DDLIKPEEEEEEEEEEEEEEEEEEGEEEEGGG 1376
            EE   E+            EK E     ++ +  +E+  E+EE+ +EEE+   +E+    
Sbjct: 416  EEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQ 475

Query: 1377 NVEKDPDGAKSQEKEEPEISTEKEDSARLDDHEEEEEEDEEPSHNEDHDADDEDDSHMES 1436
              +      K +E+EE +I  ++E   R    +EE+  ++E    E+   + E+    E 
Sbjct: 476  EAKMWRQEEKIREQEE-KIREQEEKMWR----QEEKIHEQEKIREEEKRQEQEEMWRQEE 530

Query: 1437 AEVEKEELPRESFKEVLENQETFLDLNVQPGHSNPEVLMDCGVDLTASCNSEPKELAGDP 1496
               E+EE+ R+  KE +  QE  +    +      E + D                    
Sbjct: 531  KIREQEEIWRQ--KEKIHEQEEKIRKQEEKMWRQEEKMHD------------------QE 570

Query: 1497 EAVPESDEEPPPGEQAQKQDQKNSKEVDTEFKEGNPATMEIDSETVQAVQSLTQESSEQD 1556
            E + E +E+    E+  ++ ++  +E + + +E    T E + +  +  + + ++  +  
Sbjct: 571  EKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQ 630

Query: 1557 DTFQDCAETQEACRSLQNYTRADQ 1580
            +  +     +E  R  +   R  +
Sbjct: 631  EQEEKMRRQEEKIREQEKKIREQE 654



 Score = 44.3 bits (103), Expect = 0.001
 Identities = 26/108 (24%), Positives = 51/108 (47%), Gaps = 1/108 (0%)

Query: 999  EEEREAEKEAERLMEQASCWEKEEQEILSTRANSRQSPAKVQSKNKYLHSPESRPVTGER 1058
            +EE+  E+E E++ EQ     ++E++I       R+   K++ + + +   E +    E 
Sbjct: 618  QEEKMCEQE-EKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEE 676

Query: 1059 GQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENI 1106
                +  K   +EE+    EE+  E+E     +EE+ +E +E  E  I
Sbjct: 677  KMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLEAAI 724


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.309    0.126    0.364 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 95,207,835
Number of Sequences: 37866
Number of extensions: 5480824
Number of successful extensions: 206846
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1463
Number of HSP's successfully gapped in prelim test: 1462
Number of HSP's that attempted gapping in prelim test: 48446
Number of HSP's gapped (non-prelim): 55054
length of query: 2073
length of database: 18,247,518
effective HSP length: 118
effective length of query: 1955
effective length of database: 13,779,330
effective search space: 26938590150
effective search space used: 26938590150
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 70 (31.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.