Search of human proteins with 186928833

Search of human proteins with 186928833

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|186928833 dermokine isoform 7 [Homo sapiens]
         (137 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|186928833 dermokine isoform 7 [Homo sapiens]                       293   4e-80
gi|186928831 dermokine isoform 6 [Homo sapiens]                       254   1e-68
gi|33504489 dermokine isoform 2 precursor [Homo sapiens]              254   1e-68
gi|78486558 dermokine isoform 1 precursor [Homo sapiens]              125   1e-29
gi|186928829 dermokine isoform 4 precursor [Homo sapiens]              62   1e-10
gi|186928827 dermokine isoform 5 precursor [Homo sapiens]              62   1e-10
gi|186928825 dermokine isoform 3 precursor [Homo sapiens]              62   1e-10
gi|116174780 SEC24 related gene family, member A [Homo sapiens]        30   0.48 
gi|58219064 Src homology 2 domain containing E [Homo sapiens]          28   2.4  
gi|19923391 homeobox D3 [Homo sapiens]                                 28   3.1  
gi|71043966 endonuclease/exonuclease/phosphatase family domain c...    28   3.1  
gi|22547204 hairless protein isoform a [Homo sapiens]                  27   5.3  
gi|22547207 hairless protein isoform b [Homo sapiens]                  27   5.3  
gi|4885441 solute carrier family 17 (sodium phosphate), member 4...    27   5.3  
gi|46409408 keratinocyte differentiation-associated protein [Hom...    27   5.3  
gi|253970500 Ewing sarcoma breakpoint region 1 isoform 1 [Homo s...    26   9.0  

>gi|186928833 dermokine isoform 7 [Homo sapiens]
          Length = 137

 Score =  293 bits (749), Expect = 4e-80
 Identities = 137/137 (100%), Positives = 137/137 (100%)

Query: 1   MFNFDTFWKNFKSKLGFINWDAINKNQVPPPSTRALLYFSRLWEDFKQNTPFLNWKAIIE 60
           MFNFDTFWKNFKSKLGFINWDAINKNQVPPPSTRALLYFSRLWEDFKQNTPFLNWKAIIE
Sbjct: 1   MFNFDTFWKNFKSKLGFINWDAINKNQVPPPSTRALLYFSRLWEDFKQNTPFLNWKAIIE 60

Query: 61  GADASSLQKRAGRADQPGAGWQEVAAVTSKNYNYNQHAYPTAYGGKYSVKTPAKGGVSPS 120
           GADASSLQKRAGRADQPGAGWQEVAAVTSKNYNYNQHAYPTAYGGKYSVKTPAKGGVSPS
Sbjct: 61  GADASSLQKRAGRADQPGAGWQEVAAVTSKNYNYNQHAYPTAYGGKYSVKTPAKGGVSPS 120

Query: 121 SSASRVQPGLLQWVKFW 137
           SSASRVQPGLLQWVKFW
Sbjct: 121 SSASRVQPGLLQWVKFW 137


>gi|186928831 dermokine isoform 6 [Homo sapiens]
          Length = 189

 Score =  254 bits (650), Expect = 1e-68
 Identities = 123/137 (89%), Positives = 123/137 (89%), Gaps = 14/137 (10%)

Query: 1   MFNFDTFWKNFKSKLGFINWDAINKNQVPPPSTRALLYFSRLWEDFKQNTPFLNWKAIIE 60
           MFNFDTFWKNFKSKLGFINWDAINKNQVPPPSTRALLYFSRLWEDFKQNTPFLNWKAIIE
Sbjct: 67  MFNFDTFWKNFKSKLGFINWDAINKNQVPPPSTRALLYFSRLWEDFKQNTPFLNWKAIIE 126

Query: 61  GADASSLQKRAGRADQPGAGWQEVAAVTSKNYNYNQHAYPTAYGGKYSVKTPAKGGVSPS 120
           GADASSLQKRAGRADQ              NYNYNQHAYPTAYGGKYSVKTPAKGGVSPS
Sbjct: 127 GADASSLQKRAGRADQ--------------NYNYNQHAYPTAYGGKYSVKTPAKGGVSPS 172

Query: 121 SSASRVQPGLLQWVKFW 137
           SSASRVQPGLLQWVKFW
Sbjct: 173 SSASRVQPGLLQWVKFW 189


>gi|33504489 dermokine isoform 2 precursor [Homo sapiens]
          Length = 476

 Score =  254 bits (650), Expect = 1e-68
 Identities = 123/137 (89%), Positives = 123/137 (89%), Gaps = 14/137 (10%)

Query: 1   MFNFDTFWKNFKSKLGFINWDAINKNQVPPPSTRALLYFSRLWEDFKQNTPFLNWKAIIE 60
           MFNFDTFWKNFKSKLGFINWDAINKNQVPPPSTRALLYFSRLWEDFKQNTPFLNWKAIIE
Sbjct: 354 MFNFDTFWKNFKSKLGFINWDAINKNQVPPPSTRALLYFSRLWEDFKQNTPFLNWKAIIE 413

Query: 61  GADASSLQKRAGRADQPGAGWQEVAAVTSKNYNYNQHAYPTAYGGKYSVKTPAKGGVSPS 120
           GADASSLQKRAGRADQ              NYNYNQHAYPTAYGGKYSVKTPAKGGVSPS
Sbjct: 414 GADASSLQKRAGRADQ--------------NYNYNQHAYPTAYGGKYSVKTPAKGGVSPS 459

Query: 121 SSASRVQPGLLQWVKFW 137
           SSASRVQPGLLQWVKFW
Sbjct: 460 SSASRVQPGLLQWVKFW 476


>gi|78486558 dermokine isoform 1 precursor [Homo sapiens]
          Length = 90

 Score =  125 bits (313), Expect = 1e-29
 Identities = 63/77 (81%), Positives = 63/77 (81%), Gaps = 14/77 (18%)

Query: 61  GADASSLQKRAGRADQPGAGWQEVAAVTSKNYNYNQHAYPTAYGGKYSVKTPAKGGVSPS 120
           GADASSLQKRAGRADQ              NYNYNQHAYPTAYGGKYSVKTPAKGGVSPS
Sbjct: 28  GADASSLQKRAGRADQ--------------NYNYNQHAYPTAYGGKYSVKTPAKGGVSPS 73

Query: 121 SSASRVQPGLLQWVKFW 137
           SSASRVQPGLLQWVKFW
Sbjct: 74  SSASRVQPGLLQWVKFW 90


>gi|186928829 dermokine isoform 4 precursor [Homo sapiens]
          Length = 386

 Score = 62.4 bits (150), Expect = 1e-10
 Identities = 26/27 (96%), Positives = 27/27 (100%)

Query: 1   MFNFDTFWKNFKSKLGFINWDAINKNQ 27
           MFNFDTFWKNFKSKLGFINWDAINK+Q
Sbjct: 354 MFNFDTFWKNFKSKLGFINWDAINKDQ 380



 Score = 26.9 bits (58), Expect = 5.3
 Identities = 9/20 (45%), Positives = 12/20 (60%)

Query: 39  FSRLWEDFKQNTPFLNWKAI 58
           F   W++FK    F+NW AI
Sbjct: 357 FDTFWKNFKSKLGFINWDAI 376


>gi|186928827 dermokine isoform 5 precursor [Homo sapiens]
          Length = 398

 Score = 62.4 bits (150), Expect = 1e-10
 Identities = 26/27 (96%), Positives = 27/27 (100%)

Query: 1   MFNFDTFWKNFKSKLGFINWDAINKNQ 27
           MFNFDTFWKNFKSKLGFINWDAINK+Q
Sbjct: 366 MFNFDTFWKNFKSKLGFINWDAINKDQ 392



 Score = 28.1 bits (61), Expect = 2.4
 Identities = 10/36 (27%), Positives = 18/36 (50%)

Query: 23  INKNQVPPPSTRALLYFSRLWEDFKQNTPFLNWKAI 58
           ++ N     ++  +  F   W++FK    F+NW AI
Sbjct: 353 VSSNMRNSETSPGMFNFDTFWKNFKSKLGFINWDAI 388


>gi|186928825 dermokine isoform 3 precursor [Homo sapiens]
          Length = 416

 Score = 62.4 bits (150), Expect = 1e-10
 Identities = 26/27 (96%), Positives = 27/27 (100%)

Query: 1   MFNFDTFWKNFKSKLGFINWDAINKNQ 27
           MFNFDTFWKNFKSKLGFINWDAINK+Q
Sbjct: 384 MFNFDTFWKNFKSKLGFINWDAINKDQ 410



 Score = 26.9 bits (58), Expect = 5.3
 Identities = 9/20 (45%), Positives = 12/20 (60%)

Query: 39  FSRLWEDFKQNTPFLNWKAI 58
           F   W++FK    F+NW AI
Sbjct: 387 FDTFWKNFKSKLGFINWDAI 406


>gi|116174780 SEC24 related gene family, member A [Homo sapiens]
          Length = 1093

 Score = 30.4 bits (67), Expect = 0.48
 Identities = 24/97 (24%), Positives = 40/97 (41%), Gaps = 5/97 (5%)

Query: 30  PPSTRALLYFSRLWEDFKQN--TPFLNWKAIIEGADASSLQKRAGRADQPGAGWQEVAAV 87
           PP  RAL   +  + D  Q      +N + I    +  S+   +   +  G G      +
Sbjct: 218 PPPVRALTPLTSSYRDVPQPLFNSAVNQEGITSNTNNGSMVVHSSYDEIEGGGLLATPQL 277

Query: 88  TSKNYNYNQ---HAYPTAYGGKYSVKTPAKGGVSPSS 121
           T+KN   ++   ++YP+   G  +   P   GV PSS
Sbjct: 278 TNKNPKMSRSVGYSYPSLPPGYQNTTPPGATGVPPSS 314


>gi|58219064 Src homology 2 domain containing E [Homo sapiens]
          Length = 495

 Score = 28.1 bits (61), Expect = 2.4
 Identities = 22/83 (26%), Positives = 31/83 (37%), Gaps = 3/83 (3%)

Query: 43  WEDFKQNTPFLNWKAIIEGADASSLQKRAGRADQPGAGWQEVAAVTSKNYNYNQHAYPTA 102
           W      +  L W + +  + A +L  RAGR     A W +   +  K    ++ A P  
Sbjct: 3   WSPTPGASACLGWASSLACSTAPTLLGRAGRGPLMAAKWFKEFPLNLK--TVSERAKPGG 60

Query: 103 YGGKYSVKTPAKGGVSPSSSASR 125
            GGK   K    GG  P     R
Sbjct: 61  GGGKLR-KNSEAGGAGPGPGKGR 82


>gi|19923391 homeobox D3 [Homo sapiens]
          Length = 432

 Score = 27.7 bits (60), Expect = 3.1
 Identities = 14/36 (38%), Positives = 20/36 (55%), Gaps = 1/36 (2%)

Query: 100 PTAYGGKYSVKTPAKGGVSPSSSASRVQPGLLQWVK 135
           PT  GG    K P KGG + SSS++ +   +  W+K
Sbjct: 131 PTNPGGGVPAKKP-KGGPNASSSSATISKQIFPWMK 165


>gi|71043966 endonuclease/exonuclease/phosphatase family domain
           containing 1 [Homo sapiens]
          Length = 569

 Score = 27.7 bits (60), Expect = 3.1
 Identities = 19/64 (29%), Positives = 30/64 (46%), Gaps = 12/64 (18%)

Query: 55  WKAIIEGADASSLQKRAGRADQPGAGWQEVAAV---------TSKNYNYNQHAYPTAYGG 105
           WKA++    +S LQK AG A   G  W   A +         +S +  + + A P+ Y G
Sbjct: 333 WKAVVAEKPSSQLQKGAGYA---GFLWDAAAGMELRDAGSQESSPSNGHGKLAGPSPYLG 389

Query: 106 KYSV 109
           ++ V
Sbjct: 390 RFKV 393


>gi|22547204 hairless protein isoform a [Homo sapiens]
          Length = 1189

 Score = 26.9 bits (58), Expect = 5.3
 Identities = 16/46 (34%), Positives = 24/46 (52%), Gaps = 7/46 (15%)

Query: 59  IEGADASSLQKRA-----GRADQPGAGWQEV--AAVTSKNYNYNQH 97
           ++GA  S   KR      G A+Q   GWQEV   ++ +K+ +  QH
Sbjct: 419 VQGAMGSPAPKRPPDPFPGTAEQGAGGWQEVRDTSIGNKDVDSGQH 464


>gi|22547207 hairless protein isoform b [Homo sapiens]
          Length = 1134

 Score = 26.9 bits (58), Expect = 5.3
 Identities = 16/46 (34%), Positives = 24/46 (52%), Gaps = 7/46 (15%)

Query: 59  IEGADASSLQKRA-----GRADQPGAGWQEV--AAVTSKNYNYNQH 97
           ++GA  S   KR      G A+Q   GWQEV   ++ +K+ +  QH
Sbjct: 419 VQGAMGSPAPKRPPDPFPGTAEQGAGGWQEVRDTSIGNKDVDSGQH 464


>gi|4885441 solute carrier family 17 (sodium phosphate), member 4
           [Homo sapiens]
          Length = 497

 Score = 26.9 bits (58), Expect = 5.3
 Identities = 17/55 (30%), Positives = 25/55 (45%), Gaps = 9/55 (16%)

Query: 22  AINKNQVPP---------PSTRALLYFSRLWEDFKQNTPFLNWKAIIEGADASSL 67
           A+  N  PP         PST +  Y++   ++FK   P  +W   I+G   SSL
Sbjct: 63  AMVNNTAPPSQPNASTERPSTDSQGYWNETLKEFKAMAPAYDWSPEIQGIILSSL 117


>gi|46409408 keratinocyte differentiation-associated protein [Homo
          sapiens]
          Length = 99

 Score = 26.9 bits (58), Expect = 5.3
 Identities = 10/23 (43%), Positives = 15/23 (65%)

Query: 3  NFDTFWKNFKSKLGFINWDAINK 25
          N+   +++ K KL F+NWDA  K
Sbjct: 65 NWHALFESIKRKLPFLNWDAFPK 87


>gi|253970500 Ewing sarcoma breakpoint region 1 isoform 1 [Homo
           sapiens]
          Length = 661

 Score = 26.2 bits (56), Expect = 9.0
 Identities = 12/35 (34%), Positives = 20/35 (57%)

Query: 94  YNQHAYPTAYGGKYSVKTPAKGGVSPSSSASRVQP 128
           Y Q AY T+YG   +V+  + G  +P++  +  QP
Sbjct: 61  YGQTAYATSYGQPPTVEGTSTGYTTPTAPQAYSQP 95


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.131    0.428 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,033,274
Number of Sequences: 37866
Number of extensions: 239421
Number of successful extensions: 593
Number of sequences better than 10.0: 16
Number of HSP's better than 10.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 568
Number of HSP's gapped (non-prelim): 22
length of query: 137
length of database: 18,247,518
effective HSP length: 91
effective length of query: 46
effective length of database: 14,801,712
effective search space: 680878752
effective search space used: 680878752
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 56 (26.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.