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Search of human proteins with 18375655
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|18375655 protein tyrosine phosphatase, non-receptor type 18
isoform 1 [Homo sapiens]
(460 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|18375655 protein tyrosine phosphatase, non-receptor type 18 i... 941 0.0
gi|215277017 protein tyrosine phosphatase, non-receptor type 18 ... 664 0.0
gi|224586931 protein tyrosine phosphatase, non-receptor type 22 ... 283 2e-76
gi|224586929 protein tyrosine phosphatase, non-receptor type 22 ... 283 2e-76
gi|196114951 protein tyrosine phosphatase, non-receptor type 12 ... 273 3e-73
gi|241896926 protein tyrosine phosphatase, receptor type, H isof... 186 3e-47
gi|241896924 protein tyrosine phosphatase, receptor type, H isof... 186 3e-47
gi|18104993 protein tyrosine phosphatase, non-receptor type 6 is... 177 2e-44
gi|18104989 protein tyrosine phosphatase, non-receptor type 6 is... 177 2e-44
gi|18104991 protein tyrosine phosphatase, non-receptor type 6 is... 177 2e-44
gi|4506295 protein tyrosine phosphatase, non-receptor type 4 [Ho... 177 2e-44
gi|196114967 protein tyrosine phosphatase, non-receptor type 12 ... 176 5e-44
gi|33356177 protein tyrosine phosphatase, non-receptor type 11 [... 171 2e-42
gi|223941891 protein tyrosine phosphatase, non-receptor type 3 i... 170 3e-42
gi|223941888 protein tyrosine phosphatase, non-receptor type 3 i... 170 3e-42
gi|223941885 protein tyrosine phosphatase, non-receptor type 3 i... 170 3e-42
gi|223941882 protein tyrosine phosphatase, non-receptor type 3 i... 170 3e-42
gi|223941879 protein tyrosine phosphatase, non-receptor type 3 i... 170 3e-42
gi|223941876 protein tyrosine phosphatase, non-receptor type 3 i... 170 3e-42
gi|109138573 protein tyrosine phosphatase, non-receptor type 20A... 165 7e-41
gi|109138561 protein tyrosine phosphatase, non-receptor type 20A... 165 7e-41
gi|109138557 protein tyrosine phosphatase, non-receptor type 20A... 165 7e-41
gi|108802617 protein tyrosine phosphatase, non-receptor type 20 ... 165 7e-41
gi|108802607 protein tyrosine phosphatase, non-receptor type 20 ... 165 7e-41
gi|108802604 protein tyrosine phosphatase, non-receptor type 20 ... 165 7e-41
gi|148728162 protein tyrosine phosphatase, receptor type, J isof... 164 2e-40
gi|18450371 protein tyrosine phosphatase, receptor type, A isofo... 164 2e-40
gi|4506303 protein tyrosine phosphatase, receptor type, A isofor... 164 2e-40
gi|18450369 protein tyrosine phosphatase, receptor type, A isofo... 164 2e-40
gi|196114970 protein tyrosine phosphatase, non-receptor type 12 ... 162 5e-40
>gi|18375655 protein tyrosine phosphatase, non-receptor type 18
isoform 1 [Homo sapiens]
Length = 460
Score = 941 bits (2433), Expect = 0.0
Identities = 460/460 (100%), Positives = 460/460 (100%)
Query: 1 MSRSLDSARSFLERLEARGGREGAVLAGEFSDIQACSAAWKADGVCSTVAGSRPENVRKN 60
MSRSLDSARSFLERLEARGGREGAVLAGEFSDIQACSAAWKADGVCSTVAGSRPENVRKN
Sbjct: 1 MSRSLDSARSFLERLEARGGREGAVLAGEFSDIQACSAAWKADGVCSTVAGSRPENVRKN 60
Query: 61 RYKDVLPYDQTRVILSLLQEEGHSDYINGNFIRGVDGSLAYIATQGPLPHTLLDFWRLVW 120
RYKDVLPYDQTRVILSLLQEEGHSDYINGNFIRGVDGSLAYIATQGPLPHTLLDFWRLVW
Sbjct: 61 RYKDVLPYDQTRVILSLLQEEGHSDYINGNFIRGVDGSLAYIATQGPLPHTLLDFWRLVW 120
Query: 121 EFGVKVILMACREIENGRKRCERYWAQEQEPLQTGLFCITLIKEKWLNEDIMLRTLKVTF 180
EFGVKVILMACREIENGRKRCERYWAQEQEPLQTGLFCITLIKEKWLNEDIMLRTLKVTF
Sbjct: 121 EFGVKVILMACREIENGRKRCERYWAQEQEPLQTGLFCITLIKEKWLNEDIMLRTLKVTF 180
Query: 181 QKESRSVYQLQYMSWPDRGVPSSPDHMLAMVEEARRLQGSGPEPLCVHCSAGCGRTGVLC 240
QKESRSVYQLQYMSWPDRGVPSSPDHMLAMVEEARRLQGSGPEPLCVHCSAGCGRTGVLC
Sbjct: 181 QKESRSVYQLQYMSWPDRGVPSSPDHMLAMVEEARRLQGSGPEPLCVHCSAGCGRTGVLC 240
Query: 241 TVDYVRQLLLTQMIPPDFSLFDVVLKMRKQRPAAVQTEEQYRFLYHTVAQMFCSTLQNAS 300
TVDYVRQLLLTQMIPPDFSLFDVVLKMRKQRPAAVQTEEQYRFLYHTVAQMFCSTLQNAS
Sbjct: 241 TVDYVRQLLLTQMIPPDFSLFDVVLKMRKQRPAAVQTEEQYRFLYHTVAQMFCSTLQNAS 300
Query: 301 PHYQNIKENCAPLYDDALFLRTPQALLAIPRPPGGVLRSISVPGSPGHAMADTYAVVQKR 360
PHYQNIKENCAPLYDDALFLRTPQALLAIPRPPGGVLRSISVPGSPGHAMADTYAVVQKR
Sbjct: 301 PHYQNIKENCAPLYDDALFLRTPQALLAIPRPPGGVLRSISVPGSPGHAMADTYAVVQKR 360
Query: 361 GAPAGAGSGTQTGTGTGTGARSAEEAPLYSKVTPRAQRPGAHAEDARGTLPGRVPADQSP 420
GAPAGAGSGTQTGTGTGTGARSAEEAPLYSKVTPRAQRPGAHAEDARGTLPGRVPADQSP
Sbjct: 361 GAPAGAGSGTQTGTGTGTGARSAEEAPLYSKVTPRAQRPGAHAEDARGTLPGRVPADQSP 420
Query: 421 AGSGAYEDVAGGAQTGGLGFNLRIGRPKGPRDPPAEWTRV 460
AGSGAYEDVAGGAQTGGLGFNLRIGRPKGPRDPPAEWTRV
Sbjct: 421 AGSGAYEDVAGGAQTGGLGFNLRIGRPKGPRDPPAEWTRV 460
>gi|215277017 protein tyrosine phosphatase, non-receptor type 18
isoform 2 [Homo sapiens]
Length = 353
Score = 664 bits (1714), Expect = 0.0
Identities = 322/322 (100%), Positives = 322/322 (100%)
Query: 139 KRCERYWAQEQEPLQTGLFCITLIKEKWLNEDIMLRTLKVTFQKESRSVYQLQYMSWPDR 198
KRCERYWAQEQEPLQTGLFCITLIKEKWLNEDIMLRTLKVTFQKESRSVYQLQYMSWPDR
Sbjct: 32 KRCERYWAQEQEPLQTGLFCITLIKEKWLNEDIMLRTLKVTFQKESRSVYQLQYMSWPDR 91
Query: 199 GVPSSPDHMLAMVEEARRLQGSGPEPLCVHCSAGCGRTGVLCTVDYVRQLLLTQMIPPDF 258
GVPSSPDHMLAMVEEARRLQGSGPEPLCVHCSAGCGRTGVLCTVDYVRQLLLTQMIPPDF
Sbjct: 92 GVPSSPDHMLAMVEEARRLQGSGPEPLCVHCSAGCGRTGVLCTVDYVRQLLLTQMIPPDF 151
Query: 259 SLFDVVLKMRKQRPAAVQTEEQYRFLYHTVAQMFCSTLQNASPHYQNIKENCAPLYDDAL 318
SLFDVVLKMRKQRPAAVQTEEQYRFLYHTVAQMFCSTLQNASPHYQNIKENCAPLYDDAL
Sbjct: 152 SLFDVVLKMRKQRPAAVQTEEQYRFLYHTVAQMFCSTLQNASPHYQNIKENCAPLYDDAL 211
Query: 319 FLRTPQALLAIPRPPGGVLRSISVPGSPGHAMADTYAVVQKRGAPAGAGSGTQTGTGTGT 378
FLRTPQALLAIPRPPGGVLRSISVPGSPGHAMADTYAVVQKRGAPAGAGSGTQTGTGTGT
Sbjct: 212 FLRTPQALLAIPRPPGGVLRSISVPGSPGHAMADTYAVVQKRGAPAGAGSGTQTGTGTGT 271
Query: 379 GARSAEEAPLYSKVTPRAQRPGAHAEDARGTLPGRVPADQSPAGSGAYEDVAGGAQTGGL 438
GARSAEEAPLYSKVTPRAQRPGAHAEDARGTLPGRVPADQSPAGSGAYEDVAGGAQTGGL
Sbjct: 272 GARSAEEAPLYSKVTPRAQRPGAHAEDARGTLPGRVPADQSPAGSGAYEDVAGGAQTGGL 331
Query: 439 GFNLRIGRPKGPRDPPAEWTRV 460
GFNLRIGRPKGPRDPPAEWTRV
Sbjct: 332 GFNLRIGRPKGPRDPPAEWTRV 353
Score = 63.2 bits (152), Expect = 5e-10
Identities = 33/40 (82%), Positives = 34/40 (85%), Gaps = 2/40 (5%)
Query: 1 MSRSLDSARSFLERLEARGGREGAVLAGEFSDIQACSAAW 40
MSRSLDSARSFLERLEARGGREGAVLAGEFS + C W
Sbjct: 1 MSRSLDSARSFLERLEARGGREGAVLAGEFS--KRCERYW 38
>gi|224586931 protein tyrosine phosphatase, non-receptor type 22
(lymphoid) isoform 2 [Homo sapiens]
Length = 691
Score = 283 bits (724), Expect = 2e-76
Identities = 134/267 (50%), Positives = 183/267 (68%), Gaps = 2/267 (0%)
Query: 27 AGEFSDIQACSAAWKADGVCSTVAGSRPENVRKNRYKDVLPYDQTRVILSLLQEEGHSDY 86
A EF ++ S +KAD T +P+N++KNRYKD+LPYD +RV LSL+ + S Y
Sbjct: 25 ANEFLKLKRQSTKYKADKTYPTTVAEKPKNIKKNRYKDILPYDYSRVELSLITSDEDSSY 84
Query: 87 INGNFIRGVDGSLAYIATQGPLPHTLLDFWRLVWEFGVKVILMACREIENGRKRCERYWA 146
IN NFI+GV G AYIATQGPL TLLDFWR++WE+ V +I+MAC E E G+K+CERYWA
Sbjct: 85 INANFIKGVYGPKAYIATQGPLSTTLLDFWRMIWEYSVLIIVMACMEYEMGKKKCERYWA 144
Query: 147 QEQE-PLQTGLFCITLIKEKWLNEDIMLRTLKVTFQKESRSVYQLQYMSWPDRGVPSSPD 205
+ E L+ G F ++ EK D ++RTLKV F E+R++YQ Y +WPD VPSS D
Sbjct: 145 EPGEMQLEFGPFSVSCEAEK-RKSDYIIRTLKVKFNSETRTIYQFHYKNWPDHDVPSSID 203
Query: 206 HMLAMVEEARRLQGSGPEPLCVHCSAGCGRTGVLCTVDYVRQLLLTQMIPPDFSLFDVVL 265
+L ++ + R Q P+C+HCSAGCGRTGV+C +DY LL +IP +FS+F ++
Sbjct: 204 PILELIWDVRCYQEDDSVPICIHCSAGCGRTGVICAIDYTWMLLKDGIIPENFSVFSLIR 263
Query: 266 KMRKQRPAAVQTEEQYRFLYHTVAQMF 292
+MR QRP+ VQT+EQY +Y+ V ++F
Sbjct: 264 EMRTQRPSLVQTQEQYELVYNAVLELF 290
>gi|224586929 protein tyrosine phosphatase, non-receptor type 22
(lymphoid) isoform 1 [Homo sapiens]
Length = 807
Score = 283 bits (724), Expect = 2e-76
Identities = 134/267 (50%), Positives = 183/267 (68%), Gaps = 2/267 (0%)
Query: 27 AGEFSDIQACSAAWKADGVCSTVAGSRPENVRKNRYKDVLPYDQTRVILSLLQEEGHSDY 86
A EF ++ S +KAD T +P+N++KNRYKD+LPYD +RV LSL+ + S Y
Sbjct: 25 ANEFLKLKRQSTKYKADKTYPTTVAEKPKNIKKNRYKDILPYDYSRVELSLITSDEDSSY 84
Query: 87 INGNFIRGVDGSLAYIATQGPLPHTLLDFWRLVWEFGVKVILMACREIENGRKRCERYWA 146
IN NFI+GV G AYIATQGPL TLLDFWR++WE+ V +I+MAC E E G+K+CERYWA
Sbjct: 85 INANFIKGVYGPKAYIATQGPLSTTLLDFWRMIWEYSVLIIVMACMEYEMGKKKCERYWA 144
Query: 147 QEQE-PLQTGLFCITLIKEKWLNEDIMLRTLKVTFQKESRSVYQLQYMSWPDRGVPSSPD 205
+ E L+ G F ++ EK D ++RTLKV F E+R++YQ Y +WPD VPSS D
Sbjct: 145 EPGEMQLEFGPFSVSCEAEK-RKSDYIIRTLKVKFNSETRTIYQFHYKNWPDHDVPSSID 203
Query: 206 HMLAMVEEARRLQGSGPEPLCVHCSAGCGRTGVLCTVDYVRQLLLTQMIPPDFSLFDVVL 265
+L ++ + R Q P+C+HCSAGCGRTGV+C +DY LL +IP +FS+F ++
Sbjct: 204 PILELIWDVRCYQEDDSVPICIHCSAGCGRTGVICAIDYTWMLLKDGIIPENFSVFSLIR 263
Query: 266 KMRKQRPAAVQTEEQYRFLYHTVAQMF 292
+MR QRP+ VQT+EQY +Y+ V ++F
Sbjct: 264 EMRTQRPSLVQTQEQYELVYNAVLELF 290
Score = 30.8 bits (68), Expect = 2.7
Identities = 11/19 (57%), Positives = 13/19 (68%)
Query: 439 GFNLRIGRPKGPRDPPAEW 457
GF R +PKGPR+PP W
Sbjct: 787 GFANRFSKPKGPRNPPPTW 805
>gi|196114951 protein tyrosine phosphatase, non-receptor type 12
isoform 1 [Homo sapiens]
Length = 780
Score = 273 bits (697), Expect = 3e-73
Identities = 132/295 (44%), Positives = 193/295 (65%), Gaps = 9/295 (3%)
Query: 9 RSFLERLEA-----RGGREGAVLAGEFSDIQACSAAWKADGVCSTVAGSRPENVRKNRYK 63
R F++R++A G + A +F ++ S ++ + + T G + ENV+KNRYK
Sbjct: 8 RKFIQRVQAMKSPDHNGEDN--FARDFMRLRRLSTKYRTEKIYPTATGEKEENVKKNRYK 65
Query: 64 DVLPYDQTRVILSLLQEEGHSDYINGNFIRGVDGSLAYIATQGPLPHTLLDFWRLVWEFG 123
D+LP+D +RV L+L SDYIN NFI+GV G AY+ATQGPL +T++DFWR++WE+
Sbjct: 66 DILPFDHSRVKLTLKTPSQDSDYINANFIKGVYGPKAYVATQGPLANTVIDFWRMIWEYN 125
Query: 124 VKVILMACREIENGRKRCERYW-AQEQEPLQTGLFCITLIKEKWLNEDIMLRTLKVTFQK 182
V +I+MACRE E GRK+CERYW ++P+ F I+ +++ D +RTL + FQ
Sbjct: 126 VVIIVMACREFEMGRKKCERYWPLYGEDPITFAPFKIS-CEDEQARTDYFIRTLLLEFQN 184
Query: 183 ESRSVYQLQYMSWPDRGVPSSPDHMLAMVEEARRLQGSGPEPLCVHCSAGCGRTGVLCTV 242
ESR +YQ Y++WPD VPSS D +L M+ R+ Q P+C+HCSAGCGRTG +C +
Sbjct: 185 ESRRLYQFHYVNWPDHDVPSSFDSILDMISLMRKYQEHEDVPICIHCSAGCGRTGAICAI 244
Query: 243 DYVRQLLLTQMIPPDFSLFDVVLKMRKQRPAAVQTEEQYRFLYHTVAQMFCSTLQ 297
DY LL IP +F++F+++ +MR QR +AVQT+EQY ++ +AQ+F LQ
Sbjct: 245 DYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVHRAIAQLFEKQLQ 299
Score = 41.2 bits (95), Expect = 0.002
Identities = 15/21 (71%), Positives = 18/21 (85%)
Query: 438 LGFNLRIGRPKGPRDPPAEWT 458
+GF R G+PKGPRDPP+EWT
Sbjct: 760 IGFGNRCGKPKGPRDPPSEWT 780
>gi|241896926 protein tyrosine phosphatase, receptor type, H isoform
2 precursor [Homo sapiens]
Length = 937
Score = 186 bits (473), Expect = 3e-47
Identities = 112/258 (43%), Positives = 147/258 (56%), Gaps = 14/258 (5%)
Query: 47 STVAGSRPENVRKNRYKDVLPYDQTRVILSLLQEEGHSDYINGNFIRGVDGSLAYIATQG 106
S + S EN KNRY++VLPYD +RV L + EE SDYIN +F+ G+ +IATQG
Sbjct: 657 SQMVASASENNAKNRYRNVLPYDWSRVPLKPIHEEPGSDYINASFMPGLWSPQEFIATQG 716
Query: 107 PLPHTLLDFWRLVWEFGVKVILMACREIENGRKRCERYWAQEQEPLQTGLFCITL----I 162
PLP T+ DFWRLVWE ++M +E GR +CE YW + +P G +TL +
Sbjct: 717 PLPQTVGDFWRLVWEQQSHTLVMLTNCMEAGRVKCEHYWPLDSQPCTHGHLRVTLVGEEV 776
Query: 163 KEKWLNEDIMLRTLKVTFQKESRSVYQLQYMSWPDRGVPSSPDHMLAMVEEARRLQGSGP 222
E W +++L L+V QK + SV Q Y +WPD GVPSSPD +LA R+
Sbjct: 777 MENWTVRELLL--LQVEEQK-TLSVRQFHYQAWPDHGVPSSPDTLLAFWRMLRQWLDQTM 833
Query: 223 E--PLCVHCSAGCGRTGVLCTVD-YVRQLLLTQMIPPDFSLFDVVLKMRKQRPAAVQTEE 279
E P VHCSAG GRTG L +D +RQL ++ P F V KMR+ RP VQTE
Sbjct: 834 EGGPPIVHCSAGVGRTGTLIALDVLLRQLQSEGLLGP----FSFVRKMRESRPLMVQTEA 889
Query: 280 QYRFLYHTVAQMFCSTLQ 297
QY FL+ + + + Q
Sbjct: 890 QYVFLHQCILRFLQQSAQ 907
>gi|241896924 protein tyrosine phosphatase, receptor type, H isoform 1
precursor [Homo sapiens]
Length = 1115
Score = 186 bits (473), Expect = 3e-47
Identities = 112/258 (43%), Positives = 147/258 (56%), Gaps = 14/258 (5%)
Query: 47 STVAGSRPENVRKNRYKDVLPYDQTRVILSLLQEEGHSDYINGNFIRGVDGSLAYIATQG 106
S + S EN KNRY++VLPYD +RV L + EE SDYIN +F+ G+ +IATQG
Sbjct: 835 SQMVASASENNAKNRYRNVLPYDWSRVPLKPIHEEPGSDYINASFMPGLWSPQEFIATQG 894
Query: 107 PLPHTLLDFWRLVWEFGVKVILMACREIENGRKRCERYWAQEQEPLQTGLFCITL----I 162
PLP T+ DFWRLVWE ++M +E GR +CE YW + +P G +TL +
Sbjct: 895 PLPQTVGDFWRLVWEQQSHTLVMLTNCMEAGRVKCEHYWPLDSQPCTHGHLRVTLVGEEV 954
Query: 163 KEKWLNEDIMLRTLKVTFQKESRSVYQLQYMSWPDRGVPSSPDHMLAMVEEARRLQGSGP 222
E W +++L L+V QK + SV Q Y +WPD GVPSSPD +LA R+
Sbjct: 955 MENWTVRELLL--LQVEEQK-TLSVRQFHYQAWPDHGVPSSPDTLLAFWRMLRQWLDQTM 1011
Query: 223 E--PLCVHCSAGCGRTGVLCTVD-YVRQLLLTQMIPPDFSLFDVVLKMRKQRPAAVQTEE 279
E P VHCSAG GRTG L +D +RQL ++ P F V KMR+ RP VQTE
Sbjct: 1012 EGGPPIVHCSAGVGRTGTLIALDVLLRQLQSEGLLGP----FSFVRKMRESRPLMVQTEA 1067
Query: 280 QYRFLYHTVAQMFCSTLQ 297
QY FL+ + + + Q
Sbjct: 1068 QYVFLHQCILRFLQQSAQ 1085
>gi|18104993 protein tyrosine phosphatase, non-receptor type 6
isoform 3 [Homo sapiens]
Length = 624
Score = 177 bits (448), Expect = 2e-44
Identities = 99/256 (38%), Positives = 145/256 (56%), Gaps = 12/256 (4%)
Query: 51 GSRPENVRKNRYKDVLPYDQTRVILSLLQEE-GHSDYINGNFIRGV-----DGSLAYIAT 104
G RPEN KNRYK++LP+D +RVIL SDYIN N+I+ + + YIA+
Sbjct: 265 GQRPENKGKNRYKNILPFDHSRVILQGRDSNIPGSDYINANYIKNQLLGPDENAKTYIAS 324
Query: 105 QGPLPHTLLDFWRLVWEFGVKVILMACREIENGRKRCERYWAQEQEPLQTGLFCITLIKE 164
QG L T+ DFW++ W+ +VI+M RE+E GR +C YW + G + +T E
Sbjct: 325 QGCLEATVNDFWQMAWQENSRVIVMTTREVEKGRNKCVPYWPEVGMQRAYGPYSVTNCGE 384
Query: 165 KWLNEDIMLRTLKVTFQKES---RSVYQLQYMSWPDRGVPSSPDHMLAMVEEARRLQGSG 221
E LRTL+V+ R ++ QY+SWPD GVPS P +L+ +++ + Q S
Sbjct: 385 HDTTE-YKLRTLQVSPLDNGDLIREIWHYQYLSWPDHGVPSEPGGVLSFLDQINQRQESL 443
Query: 222 PE--PLCVHCSAGCGRTGVLCTVDYVRQLLLTQMIPPDFSLFDVVLKMRKQRPAAVQTEE 279
P P+ VHCSAG GRTG + +D + + + T+ + D + + +R QR VQTE
Sbjct: 444 PHAGPIIVHCSAGIGRTGTIIVIDMLMENISTKGLDCDIDIQKTIQMVRAQRSGMVQTEA 503
Query: 280 QYRFLYHTVAQMFCST 295
QY+F+Y +AQ +T
Sbjct: 504 QYKFIYVAIAQFIETT 519
>gi|18104989 protein tyrosine phosphatase, non-receptor type 6
isoform 1 [Homo sapiens]
Length = 595
Score = 177 bits (448), Expect = 2e-44
Identities = 99/256 (38%), Positives = 145/256 (56%), Gaps = 12/256 (4%)
Query: 51 GSRPENVRKNRYKDVLPYDQTRVILSLLQEE-GHSDYINGNFIRGV-----DGSLAYIAT 104
G RPEN KNRYK++LP+D +RVIL SDYIN N+I+ + + YIA+
Sbjct: 265 GQRPENKGKNRYKNILPFDHSRVILQGRDSNIPGSDYINANYIKNQLLGPDENAKTYIAS 324
Query: 105 QGPLPHTLLDFWRLVWEFGVKVILMACREIENGRKRCERYWAQEQEPLQTGLFCITLIKE 164
QG L T+ DFW++ W+ +VI+M RE+E GR +C YW + G + +T E
Sbjct: 325 QGCLEATVNDFWQMAWQENSRVIVMTTREVEKGRNKCVPYWPEVGMQRAYGPYSVTNCGE 384
Query: 165 KWLNEDIMLRTLKVTFQKES---RSVYQLQYMSWPDRGVPSSPDHMLAMVEEARRLQGSG 221
E LRTL+V+ R ++ QY+SWPD GVPS P +L+ +++ + Q S
Sbjct: 385 HDTTE-YKLRTLQVSPLDNGDLIREIWHYQYLSWPDHGVPSEPGGVLSFLDQINQRQESL 443
Query: 222 PE--PLCVHCSAGCGRTGVLCTVDYVRQLLLTQMIPPDFSLFDVVLKMRKQRPAAVQTEE 279
P P+ VHCSAG GRTG + +D + + + T+ + D + + +R QR VQTE
Sbjct: 444 PHAGPIIVHCSAGIGRTGTIIVIDMLMENISTKGLDCDIDIQKTIQMVRAQRSGMVQTEA 503
Query: 280 QYRFLYHTVAQMFCST 295
QY+F+Y +AQ +T
Sbjct: 504 QYKFIYVAIAQFIETT 519
>gi|18104991 protein tyrosine phosphatase, non-receptor type 6
isoform 2 [Homo sapiens]
Length = 597
Score = 177 bits (448), Expect = 2e-44
Identities = 99/256 (38%), Positives = 145/256 (56%), Gaps = 12/256 (4%)
Query: 51 GSRPENVRKNRYKDVLPYDQTRVILSLLQEE-GHSDYINGNFIRGV-----DGSLAYIAT 104
G RPEN KNRYK++LP+D +RVIL SDYIN N+I+ + + YIA+
Sbjct: 267 GQRPENKGKNRYKNILPFDHSRVILQGRDSNIPGSDYINANYIKNQLLGPDENAKTYIAS 326
Query: 105 QGPLPHTLLDFWRLVWEFGVKVILMACREIENGRKRCERYWAQEQEPLQTGLFCITLIKE 164
QG L T+ DFW++ W+ +VI+M RE+E GR +C YW + G + +T E
Sbjct: 327 QGCLEATVNDFWQMAWQENSRVIVMTTREVEKGRNKCVPYWPEVGMQRAYGPYSVTNCGE 386
Query: 165 KWLNEDIMLRTLKVTFQKES---RSVYQLQYMSWPDRGVPSSPDHMLAMVEEARRLQGSG 221
E LRTL+V+ R ++ QY+SWPD GVPS P +L+ +++ + Q S
Sbjct: 387 HDTTE-YKLRTLQVSPLDNGDLIREIWHYQYLSWPDHGVPSEPGGVLSFLDQINQRQESL 445
Query: 222 PE--PLCVHCSAGCGRTGVLCTVDYVRQLLLTQMIPPDFSLFDVVLKMRKQRPAAVQTEE 279
P P+ VHCSAG GRTG + +D + + + T+ + D + + +R QR VQTE
Sbjct: 446 PHAGPIIVHCSAGIGRTGTIIVIDMLMENISTKGLDCDIDIQKTIQMVRAQRSGMVQTEA 505
Query: 280 QYRFLYHTVAQMFCST 295
QY+F+Y +AQ +T
Sbjct: 506 QYKFIYVAIAQFIETT 521
>gi|4506295 protein tyrosine phosphatase, non-receptor type 4 [Homo
sapiens]
Length = 926
Score = 177 bits (448), Expect = 2e-44
Identities = 97/244 (39%), Positives = 138/244 (56%), Gaps = 13/244 (5%)
Query: 54 PENVRKNRYKDVLPYDQTRVILSLLQEEGHSDYINGNFIRGVDGSLA----YIATQGPLP 109
P+N+ KNRY+D+ PYD TRVIL +G+ DYIN N+I S + YIA QGPLP
Sbjct: 677 PQNISKNRYRDISPYDATRVIL-----KGNEDYINANYINMEIPSSSIINQYIACQGPLP 731
Query: 110 HTLLDFWRLVWEFGVKVILMACREIENGRKRCERYWAQEQEPLQTGLFCITLIKEKWLNE 169
HT DFW++ WE G +++M ++E GR +C +YW + G + +T E+
Sbjct: 732 HTCTDFWQMTWEQGSSMVVMLTTQVERGRVKCHQYWPEPTGSSSYGCYQVTCHSEEGNTA 791
Query: 170 DIMLR-TLKVTFQKESRSVYQLQYMSWPDRGVPSSPDHMLAMVEEARRLQGSGPEPLCVH 228
I + TL + ESR + Q+QY++WPD GVP L V R + EP+ VH
Sbjct: 792 YIFRKMTLFNQEKNESRPLTQIQYIAWPDHGVPDDSSDFLDFVCHVRNKRAGKEEPVVVH 851
Query: 229 CSAGCGRTGVLCTVDYVRQLLLTQMIPPDFSLFDVVLKMRKQRPAAVQTEEQYRFLYHTV 288
CSAG GRTGVL T++ + L + P + L D+V MR QR +QT QYRF+ +
Sbjct: 852 CSAGIGRTGVLITME--TAMCLIECNQPVYPL-DIVRTMRDQRAMMIQTPSQYRFVCEAI 908
Query: 289 AQMF 292
+++
Sbjct: 909 LKVY 912
>gi|196114967 protein tyrosine phosphatase, non-receptor type 12
isoform 2 [Homo sapiens]
Length = 661
Score = 176 bits (445), Expect = 5e-44
Identities = 83/181 (45%), Positives = 119/181 (65%), Gaps = 2/181 (1%)
Query: 118 LVWEFGVKVILMACREIENGRKRCERYWA-QEQEPLQTGLFCITLIKEKWLNEDIMLRTL 176
++WE+ V +I+MACRE E GRK+CERYW ++P+ F I+ E+ D +RTL
Sbjct: 1 MIWEYNVVIIVMACREFEMGRKKCERYWPLYGEDPITFAPFKISCEDEQ-ARTDYFIRTL 59
Query: 177 KVTFQKESRSVYQLQYMSWPDRGVPSSPDHMLAMVEEARRLQGSGPEPLCVHCSAGCGRT 236
+ FQ ESR +YQ Y++WPD VPSS D +L M+ R+ Q P+C+HCSAGCGRT
Sbjct: 60 LLEFQNESRRLYQFHYVNWPDHDVPSSFDSILDMISLMRKYQEHEDVPICIHCSAGCGRT 119
Query: 237 GVLCTVDYVRQLLLTQMIPPDFSLFDVVLKMRKQRPAAVQTEEQYRFLYHTVAQMFCSTL 296
G +C +DY LL IP +F++F+++ +MR QR +AVQT+EQY ++ +AQ+F L
Sbjct: 120 GAICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVHRAIAQLFEKQL 179
Query: 297 Q 297
Q
Sbjct: 180 Q 180
Score = 41.2 bits (95), Expect = 0.002
Identities = 15/21 (71%), Positives = 18/21 (85%)
Query: 438 LGFNLRIGRPKGPRDPPAEWT 458
+GF R G+PKGPRDPP+EWT
Sbjct: 641 IGFGNRCGKPKGPRDPPSEWT 661
>gi|33356177 protein tyrosine phosphatase, non-receptor type 11
[Homo sapiens]
Length = 593
Score = 171 bits (432), Expect = 2e-42
Identities = 103/271 (38%), Positives = 145/271 (53%), Gaps = 16/271 (5%)
Query: 51 GSRPENVRKNRYKDVLPYDQTRVILSLLQ-EEGHSDYINGNFI--------RGVDGSLAY 101
G R EN KNRYK++LP+D TRV+L E SDYIN N I +Y
Sbjct: 268 GQRQENKNKNRYKNILPFDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSY 327
Query: 102 IATQGPLPHTLLDFWRLVWEFGVKVILMACREIENGRKRCERYWAQEQEPLQTGLFCITL 161
IATQG L +T+ DFWR+V++ +VI+M +E+E G+ +C +YW E + G+ +
Sbjct: 328 IATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRN 387
Query: 162 IKEKWLNEDIMLRTLKVTFQKE---SRSVYQLQYMSWPDRGVPSSPDHMLAMVEEARRLQ 218
+KE D LR LK++ + R+V+Q + +WPD GVPS P +L +EE Q
Sbjct: 388 VKES-AAHDYTLRELKLSKVGQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQ 446
Query: 219 GS--GPEPLCVHCSAGCGRTGVLCTVDYVRQLLLTQMIPPDFSLFDVVLKMRKQRPAAVQ 276
S P+ VHCSAG GRTG +D + ++ + + D + + +R QR VQ
Sbjct: 447 ESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQ 506
Query: 277 TEEQYRFLYHTVAQMFCSTLQNASPHYQNIK 307
TE QYRF+Y V Q + TLQ Q K
Sbjct: 507 TEAQYRFIYMAV-QHYIETLQRRIEEEQKSK 536
>gi|223941891 protein tyrosine phosphatase, non-receptor type 3
isoform 6 [Homo sapiens]
Length = 581
Score = 170 bits (430), Expect = 3e-42
Identities = 102/257 (39%), Positives = 140/257 (54%), Gaps = 15/257 (5%)
Query: 41 KADGVCSTVAGSRPENVRKNRYKDVLPYDQTRVILSLLQEEGHSDYINGNFIR----GVD 96
K G+ T A P+N+ KNRYKDVLPYD TRV+L +G+ DYIN +++ +
Sbjct: 324 KKPGLAITFA-KLPQNLDKNRYKDVLPYDTTRVLL-----QGNEDYINASYVNMEIPAAN 377
Query: 97 GSLAYIATQGPLPHTLLDFWRLVWEFGVKVILMACREIENGRKRCERYWAQEQEPLQTGL 156
YIATQGPLPHT FW++VW+ + +I+M E GR +C +YW + + G
Sbjct: 378 LVNKYIATQGPLPHTCAQFWQVVWDQKLSLIVMLTTLTERGRTKCHQYWPDPPDVMNHGG 437
Query: 157 FCITLIKEKWLNEDIMLRTLKVTFQK-ESRSVYQLQYMSWPDRGVPSSPDHMLAMVEEAR 215
F I E + L Q E +V LQY++WPD GVP L V R
Sbjct: 438 FHIQCQSEDCTIAYVSREMLVTNTQTGEEHTVTHLQYVAWPDHGVPDDSSDFLEFVNYVR 497
Query: 216 RLQGSGPEPLCVHCSAGCGRTGVLCTVDYVRQLLLTQMIPPDFSLFDVVLKMRKQRPAAV 275
L+ EP+ VHCSAG GRTGVL T++ + LT+ P + L D+V KMR QR V
Sbjct: 498 SLRVDS-EPVLVHCSAGIGRTGVLVTME--TAMCLTERNLPIYPL-DIVRKMRDQRAMMV 553
Query: 276 QTEEQYRFLYHTVAQMF 292
QT QY+F+ + +++
Sbjct: 554 QTSSQYKFVCEAILRVY 570
>gi|223941888 protein tyrosine phosphatase, non-receptor type 3
isoform 5 [Homo sapiens]
Length = 626
Score = 170 bits (430), Expect = 3e-42
Identities = 102/257 (39%), Positives = 140/257 (54%), Gaps = 15/257 (5%)
Query: 41 KADGVCSTVAGSRPENVRKNRYKDVLPYDQTRVILSLLQEEGHSDYINGNFIR----GVD 96
K G+ T A P+N+ KNRYKDVLPYD TRV+L +G+ DYIN +++ +
Sbjct: 369 KKPGLAITFA-KLPQNLDKNRYKDVLPYDTTRVLL-----QGNEDYINASYVNMEIPAAN 422
Query: 97 GSLAYIATQGPLPHTLLDFWRLVWEFGVKVILMACREIENGRKRCERYWAQEQEPLQTGL 156
YIATQGPLPHT FW++VW+ + +I+M E GR +C +YW + + G
Sbjct: 423 LVNKYIATQGPLPHTCAQFWQVVWDQKLSLIVMLTTLTERGRTKCHQYWPDPPDVMNHGG 482
Query: 157 FCITLIKEKWLNEDIMLRTLKVTFQK-ESRSVYQLQYMSWPDRGVPSSPDHMLAMVEEAR 215
F I E + L Q E +V LQY++WPD GVP L V R
Sbjct: 483 FHIQCQSEDCTIAYVSREMLVTNTQTGEEHTVTHLQYVAWPDHGVPDDSSDFLEFVNYVR 542
Query: 216 RLQGSGPEPLCVHCSAGCGRTGVLCTVDYVRQLLLTQMIPPDFSLFDVVLKMRKQRPAAV 275
L+ EP+ VHCSAG GRTGVL T++ + LT+ P + L D+V KMR QR V
Sbjct: 543 SLRVDS-EPVLVHCSAGIGRTGVLVTME--TAMCLTERNLPIYPL-DIVRKMRDQRAMMV 598
Query: 276 QTEEQYRFLYHTVAQMF 292
QT QY+F+ + +++
Sbjct: 599 QTSSQYKFVCEAILRVY 615
>gi|223941885 protein tyrosine phosphatase, non-receptor type 3
isoform 4 [Homo sapiens]
Length = 737
Score = 170 bits (430), Expect = 3e-42
Identities = 102/257 (39%), Positives = 140/257 (54%), Gaps = 15/257 (5%)
Query: 41 KADGVCSTVAGSRPENVRKNRYKDVLPYDQTRVILSLLQEEGHSDYINGNFIR----GVD 96
K G+ T A P+N+ KNRYKDVLPYD TRV+L +G+ DYIN +++ +
Sbjct: 480 KKPGLAITFA-KLPQNLDKNRYKDVLPYDTTRVLL-----QGNEDYINASYVNMEIPAAN 533
Query: 97 GSLAYIATQGPLPHTLLDFWRLVWEFGVKVILMACREIENGRKRCERYWAQEQEPLQTGL 156
YIATQGPLPHT FW++VW+ + +I+M E GR +C +YW + + G
Sbjct: 534 LVNKYIATQGPLPHTCAQFWQVVWDQKLSLIVMLTTLTERGRTKCHQYWPDPPDVMNHGG 593
Query: 157 FCITLIKEKWLNEDIMLRTLKVTFQK-ESRSVYQLQYMSWPDRGVPSSPDHMLAMVEEAR 215
F I E + L Q E +V LQY++WPD GVP L V R
Sbjct: 594 FHIQCQSEDCTIAYVSREMLVTNTQTGEEHTVTHLQYVAWPDHGVPDDSSDFLEFVNYVR 653
Query: 216 RLQGSGPEPLCVHCSAGCGRTGVLCTVDYVRQLLLTQMIPPDFSLFDVVLKMRKQRPAAV 275
L+ EP+ VHCSAG GRTGVL T++ + LT+ P + L D+V KMR QR V
Sbjct: 654 SLRVDS-EPVLVHCSAGIGRTGVLVTME--TAMCLTERNLPIYPL-DIVRKMRDQRAMMV 709
Query: 276 QTEEQYRFLYHTVAQMF 292
QT QY+F+ + +++
Sbjct: 710 QTSSQYKFVCEAILRVY 726
>gi|223941882 protein tyrosine phosphatase, non-receptor type 3
isoform 3 [Homo sapiens]
Length = 782
Score = 170 bits (430), Expect = 3e-42
Identities = 102/257 (39%), Positives = 140/257 (54%), Gaps = 15/257 (5%)
Query: 41 KADGVCSTVAGSRPENVRKNRYKDVLPYDQTRVILSLLQEEGHSDYINGNFIR----GVD 96
K G+ T A P+N+ KNRYKDVLPYD TRV+L +G+ DYIN +++ +
Sbjct: 525 KKPGLAITFA-KLPQNLDKNRYKDVLPYDTTRVLL-----QGNEDYINASYVNMEIPAAN 578
Query: 97 GSLAYIATQGPLPHTLLDFWRLVWEFGVKVILMACREIENGRKRCERYWAQEQEPLQTGL 156
YIATQGPLPHT FW++VW+ + +I+M E GR +C +YW + + G
Sbjct: 579 LVNKYIATQGPLPHTCAQFWQVVWDQKLSLIVMLTTLTERGRTKCHQYWPDPPDVMNHGG 638
Query: 157 FCITLIKEKWLNEDIMLRTLKVTFQK-ESRSVYQLQYMSWPDRGVPSSPDHMLAMVEEAR 215
F I E + L Q E +V LQY++WPD GVP L V R
Sbjct: 639 FHIQCQSEDCTIAYVSREMLVTNTQTGEEHTVTHLQYVAWPDHGVPDDSSDFLEFVNYVR 698
Query: 216 RLQGSGPEPLCVHCSAGCGRTGVLCTVDYVRQLLLTQMIPPDFSLFDVVLKMRKQRPAAV 275
L+ EP+ VHCSAG GRTGVL T++ + LT+ P + L D+V KMR QR V
Sbjct: 699 SLRVDS-EPVLVHCSAGIGRTGVLVTME--TAMCLTERNLPIYPL-DIVRKMRDQRAMMV 754
Query: 276 QTEEQYRFLYHTVAQMF 292
QT QY+F+ + +++
Sbjct: 755 QTSSQYKFVCEAILRVY 771
>gi|223941879 protein tyrosine phosphatase, non-receptor type 3
isoform 2 [Homo sapiens]
Length = 868
Score = 170 bits (430), Expect = 3e-42
Identities = 102/257 (39%), Positives = 140/257 (54%), Gaps = 15/257 (5%)
Query: 41 KADGVCSTVAGSRPENVRKNRYKDVLPYDQTRVILSLLQEEGHSDYINGNFIR----GVD 96
K G+ T A P+N+ KNRYKDVLPYD TRV+L +G+ DYIN +++ +
Sbjct: 611 KKPGLAITFA-KLPQNLDKNRYKDVLPYDTTRVLL-----QGNEDYINASYVNMEIPAAN 664
Query: 97 GSLAYIATQGPLPHTLLDFWRLVWEFGVKVILMACREIENGRKRCERYWAQEQEPLQTGL 156
YIATQGPLPHT FW++VW+ + +I+M E GR +C +YW + + G
Sbjct: 665 LVNKYIATQGPLPHTCAQFWQVVWDQKLSLIVMLTTLTERGRTKCHQYWPDPPDVMNHGG 724
Query: 157 FCITLIKEKWLNEDIMLRTLKVTFQK-ESRSVYQLQYMSWPDRGVPSSPDHMLAMVEEAR 215
F I E + L Q E +V LQY++WPD GVP L V R
Sbjct: 725 FHIQCQSEDCTIAYVSREMLVTNTQTGEEHTVTHLQYVAWPDHGVPDDSSDFLEFVNYVR 784
Query: 216 RLQGSGPEPLCVHCSAGCGRTGVLCTVDYVRQLLLTQMIPPDFSLFDVVLKMRKQRPAAV 275
L+ EP+ VHCSAG GRTGVL T++ + LT+ P + L D+V KMR QR V
Sbjct: 785 SLRVDS-EPVLVHCSAGIGRTGVLVTME--TAMCLTERNLPIYPL-DIVRKMRDQRAMMV 840
Query: 276 QTEEQYRFLYHTVAQMF 292
QT QY+F+ + +++
Sbjct: 841 QTSSQYKFVCEAILRVY 857
>gi|223941876 protein tyrosine phosphatase, non-receptor type 3
isoform 1 [Homo sapiens]
Length = 913
Score = 170 bits (430), Expect = 3e-42
Identities = 102/257 (39%), Positives = 140/257 (54%), Gaps = 15/257 (5%)
Query: 41 KADGVCSTVAGSRPENVRKNRYKDVLPYDQTRVILSLLQEEGHSDYINGNFIR----GVD 96
K G+ T A P+N+ KNRYKDVLPYD TRV+L +G+ DYIN +++ +
Sbjct: 656 KKPGLAITFA-KLPQNLDKNRYKDVLPYDTTRVLL-----QGNEDYINASYVNMEIPAAN 709
Query: 97 GSLAYIATQGPLPHTLLDFWRLVWEFGVKVILMACREIENGRKRCERYWAQEQEPLQTGL 156
YIATQGPLPHT FW++VW+ + +I+M E GR +C +YW + + G
Sbjct: 710 LVNKYIATQGPLPHTCAQFWQVVWDQKLSLIVMLTTLTERGRTKCHQYWPDPPDVMNHGG 769
Query: 157 FCITLIKEKWLNEDIMLRTLKVTFQK-ESRSVYQLQYMSWPDRGVPSSPDHMLAMVEEAR 215
F I E + L Q E +V LQY++WPD GVP L V R
Sbjct: 770 FHIQCQSEDCTIAYVSREMLVTNTQTGEEHTVTHLQYVAWPDHGVPDDSSDFLEFVNYVR 829
Query: 216 RLQGSGPEPLCVHCSAGCGRTGVLCTVDYVRQLLLTQMIPPDFSLFDVVLKMRKQRPAAV 275
L+ EP+ VHCSAG GRTGVL T++ + LT+ P + L D+V KMR QR V
Sbjct: 830 SLRVDS-EPVLVHCSAGIGRTGVLVTME--TAMCLTERNLPIYPL-DIVRKMRDQRAMMV 885
Query: 276 QTEEQYRFLYHTVAQMF 292
QT QY+F+ + +++
Sbjct: 886 QTSSQYKFVCEAILRVY 902
>gi|109138573 protein tyrosine phosphatase, non-receptor type 20A
isoform 8 [Homo sapiens]
Length = 339
Score = 165 bits (418), Expect = 7e-41
Identities = 102/247 (41%), Positives = 142/247 (57%), Gaps = 16/247 (6%)
Query: 50 AGSRPENVRKNRYKDVLPYDQTRVILSLLQEEGHSDYINGNFIRGVD--GSLAYIATQGP 107
+G++P N KNRY+D+LPYD TRV L + DYIN ++IR V+ YIATQGP
Sbjct: 96 SGNQPSNREKNRYRDILPYDSTRVPLGKSK-----DYINASYIRIVNCGEEYFYIATQGP 150
Query: 108 LPHTLLDFWRLVWEFGVKVILMACREIENGRKRCERYW-AQEQEPLQTGLFCITLIKEKW 166
L T+ DFW++V E VI M REIE G +C YW ++PL+ F + L +
Sbjct: 151 LLSTIDDFWQMVLENNSNVIAMITREIEGGIIKCYHYWPISLKKPLELKHFRVFLENYQI 210
Query: 167 LNEDIMLRTLKVTFQK--ESRSVYQLQYMSWPDRGVPSSPDHMLAMVEEARRLQGSGPEP 224
L + ++R +V + S SV QLQ+ WPD G P+S D + + AR+ +G P
Sbjct: 211 L-QYFIIRMFQVVEKSTGTSHSVKQLQFTKWPDHGTPASADSFIKYIRYARKSHLTG--P 267
Query: 225 LCVHCSAGCGRTGVLCTVDYVRQLLLTQMIPPDFSLFDVVLKMRKQRPAAVQTEEQYRFL 284
+ VHCSAG GRTGV VD V ++ F++ D+V +MR+QR VQT+EQY F
Sbjct: 268 MVVHCSAGIGRTGVFLCVDVVFCAIVKNC---SFNIMDIVAQMREQRSGMVQTKEQYHFC 324
Query: 285 YHTVAQM 291
Y V ++
Sbjct: 325 YDIVLEV 331
>gi|109138561 protein tyrosine phosphatase, non-receptor type 20A
isoform 3 [Homo sapiens]
Length = 411
Score = 165 bits (418), Expect = 7e-41
Identities = 102/247 (41%), Positives = 142/247 (57%), Gaps = 16/247 (6%)
Query: 50 AGSRPENVRKNRYKDVLPYDQTRVILSLLQEEGHSDYINGNFIRGVD--GSLAYIATQGP 107
+G++P N KNRY+D+LPYD TRV L + DYIN ++IR V+ YIATQGP
Sbjct: 168 SGNQPSNREKNRYRDILPYDSTRVPLGKSK-----DYINASYIRIVNCGEEYFYIATQGP 222
Query: 108 LPHTLLDFWRLVWEFGVKVILMACREIENGRKRCERYW-AQEQEPLQTGLFCITLIKEKW 166
L T+ DFW++V E VI M REIE G +C YW ++PL+ F + L +
Sbjct: 223 LLSTIDDFWQMVLENNSNVIAMITREIEGGIIKCYHYWPISLKKPLELKHFRVFLENYQI 282
Query: 167 LNEDIMLRTLKVTFQK--ESRSVYQLQYMSWPDRGVPSSPDHMLAMVEEARRLQGSGPEP 224
L + ++R +V + S SV QLQ+ WPD G P+S D + + AR+ +G P
Sbjct: 283 L-QYFIIRMFQVVEKSTGTSHSVKQLQFTKWPDHGTPASADSFIKYIRYARKSHLTG--P 339
Query: 225 LCVHCSAGCGRTGVLCTVDYVRQLLLTQMIPPDFSLFDVVLKMRKQRPAAVQTEEQYRFL 284
+ VHCSAG GRTGV VD V ++ F++ D+V +MR+QR VQT+EQY F
Sbjct: 340 MVVHCSAGIGRTGVFLCVDVVFCAIVKNC---SFNIMDIVAQMREQRSGMVQTKEQYHFC 396
Query: 285 YHTVAQM 291
Y V ++
Sbjct: 397 YDIVLEV 403
>gi|109138557 protein tyrosine phosphatase, non-receptor type 20A
isoform 1 [Homo sapiens]
Length = 420
Score = 165 bits (418), Expect = 7e-41
Identities = 102/247 (41%), Positives = 142/247 (57%), Gaps = 16/247 (6%)
Query: 50 AGSRPENVRKNRYKDVLPYDQTRVILSLLQEEGHSDYINGNFIRGVD--GSLAYIATQGP 107
+G++P N KNRY+D+LPYD TRV L + DYIN ++IR V+ YIATQGP
Sbjct: 177 SGNQPSNREKNRYRDILPYDSTRVPLGKSK-----DYINASYIRIVNCGEEYFYIATQGP 231
Query: 108 LPHTLLDFWRLVWEFGVKVILMACREIENGRKRCERYW-AQEQEPLQTGLFCITLIKEKW 166
L T+ DFW++V E VI M REIE G +C YW ++PL+ F + L +
Sbjct: 232 LLSTIDDFWQMVLENNSNVIAMITREIEGGIIKCYHYWPISLKKPLELKHFRVFLENYQI 291
Query: 167 LNEDIMLRTLKVTFQK--ESRSVYQLQYMSWPDRGVPSSPDHMLAMVEEARRLQGSGPEP 224
L + ++R +V + S SV QLQ+ WPD G P+S D + + AR+ +G P
Sbjct: 292 L-QYFIIRMFQVVEKSTGTSHSVKQLQFTKWPDHGTPASADSFIKYIRYARKSHLTG--P 348
Query: 225 LCVHCSAGCGRTGVLCTVDYVRQLLLTQMIPPDFSLFDVVLKMRKQRPAAVQTEEQYRFL 284
+ VHCSAG GRTGV VD V ++ F++ D+V +MR+QR VQT+EQY F
Sbjct: 349 MVVHCSAGIGRTGVFLCVDVVFCAIVKNC---SFNIMDIVAQMREQRSGMVQTKEQYHFC 405
Query: 285 YHTVAQM 291
Y V ++
Sbjct: 406 YDIVLEV 412
>gi|108802617 protein tyrosine phosphatase, non-receptor type 20
isoform 8 [Homo sapiens]
Length = 339
Score = 165 bits (418), Expect = 7e-41
Identities = 102/247 (41%), Positives = 142/247 (57%), Gaps = 16/247 (6%)
Query: 50 AGSRPENVRKNRYKDVLPYDQTRVILSLLQEEGHSDYINGNFIRGVD--GSLAYIATQGP 107
+G++P N KNRY+D+LPYD TRV L + DYIN ++IR V+ YIATQGP
Sbjct: 96 SGNQPSNREKNRYRDILPYDSTRVPLGKSK-----DYINASYIRIVNCGEEYFYIATQGP 150
Query: 108 LPHTLLDFWRLVWEFGVKVILMACREIENGRKRCERYW-AQEQEPLQTGLFCITLIKEKW 166
L T+ DFW++V E VI M REIE G +C YW ++PL+ F + L +
Sbjct: 151 LLSTIDDFWQMVLENNSNVIAMITREIEGGIIKCYHYWPISLKKPLELKHFRVFLENYQI 210
Query: 167 LNEDIMLRTLKVTFQK--ESRSVYQLQYMSWPDRGVPSSPDHMLAMVEEARRLQGSGPEP 224
L + ++R +V + S SV QLQ+ WPD G P+S D + + AR+ +G P
Sbjct: 211 L-QYFIIRMFQVVEKSTGTSHSVKQLQFTKWPDHGTPASADSFIKYIRYARKSHLTG--P 267
Query: 225 LCVHCSAGCGRTGVLCTVDYVRQLLLTQMIPPDFSLFDVVLKMRKQRPAAVQTEEQYRFL 284
+ VHCSAG GRTGV VD V ++ F++ D+V +MR+QR VQT+EQY F
Sbjct: 268 MVVHCSAGIGRTGVFLCVDVVFCAIVKNC---SFNIMDIVAQMREQRSGMVQTKEQYHFC 324
Query: 285 YHTVAQM 291
Y V ++
Sbjct: 325 YDIVLEV 331
>gi|108802607 protein tyrosine phosphatase, non-receptor type 20
isoform 3 [Homo sapiens]
Length = 411
Score = 165 bits (418), Expect = 7e-41
Identities = 102/247 (41%), Positives = 142/247 (57%), Gaps = 16/247 (6%)
Query: 50 AGSRPENVRKNRYKDVLPYDQTRVILSLLQEEGHSDYINGNFIRGVD--GSLAYIATQGP 107
+G++P N KNRY+D+LPYD TRV L + DYIN ++IR V+ YIATQGP
Sbjct: 168 SGNQPSNREKNRYRDILPYDSTRVPLGKSK-----DYINASYIRIVNCGEEYFYIATQGP 222
Query: 108 LPHTLLDFWRLVWEFGVKVILMACREIENGRKRCERYW-AQEQEPLQTGLFCITLIKEKW 166
L T+ DFW++V E VI M REIE G +C YW ++PL+ F + L +
Sbjct: 223 LLSTIDDFWQMVLENNSNVIAMITREIEGGIIKCYHYWPISLKKPLELKHFRVFLENYQI 282
Query: 167 LNEDIMLRTLKVTFQK--ESRSVYQLQYMSWPDRGVPSSPDHMLAMVEEARRLQGSGPEP 224
L + ++R +V + S SV QLQ+ WPD G P+S D + + AR+ +G P
Sbjct: 283 L-QYFIIRMFQVVEKSTGTSHSVKQLQFTKWPDHGTPASADSFIKYIRYARKSHLTG--P 339
Query: 225 LCVHCSAGCGRTGVLCTVDYVRQLLLTQMIPPDFSLFDVVLKMRKQRPAAVQTEEQYRFL 284
+ VHCSAG GRTGV VD V ++ F++ D+V +MR+QR VQT+EQY F
Sbjct: 340 MVVHCSAGIGRTGVFLCVDVVFCAIVKNC---SFNIMDIVAQMREQRSGMVQTKEQYHFC 396
Query: 285 YHTVAQM 291
Y V ++
Sbjct: 397 YDIVLEV 403
>gi|108802604 protein tyrosine phosphatase, non-receptor type 20
isoform 1 [Homo sapiens]
Length = 420
Score = 165 bits (418), Expect = 7e-41
Identities = 102/247 (41%), Positives = 142/247 (57%), Gaps = 16/247 (6%)
Query: 50 AGSRPENVRKNRYKDVLPYDQTRVILSLLQEEGHSDYINGNFIRGVD--GSLAYIATQGP 107
+G++P N KNRY+D+LPYD TRV L + DYIN ++IR V+ YIATQGP
Sbjct: 177 SGNQPSNREKNRYRDILPYDSTRVPLGKSK-----DYINASYIRIVNCGEEYFYIATQGP 231
Query: 108 LPHTLLDFWRLVWEFGVKVILMACREIENGRKRCERYW-AQEQEPLQTGLFCITLIKEKW 166
L T+ DFW++V E VI M REIE G +C YW ++PL+ F + L +
Sbjct: 232 LLSTIDDFWQMVLENNSNVIAMITREIEGGIIKCYHYWPISLKKPLELKHFRVFLENYQI 291
Query: 167 LNEDIMLRTLKVTFQK--ESRSVYQLQYMSWPDRGVPSSPDHMLAMVEEARRLQGSGPEP 224
L + ++R +V + S SV QLQ+ WPD G P+S D + + AR+ +G P
Sbjct: 292 L-QYFIIRMFQVVEKSTGTSHSVKQLQFTKWPDHGTPASADSFIKYIRYARKSHLTG--P 348
Query: 225 LCVHCSAGCGRTGVLCTVDYVRQLLLTQMIPPDFSLFDVVLKMRKQRPAAVQTEEQYRFL 284
+ VHCSAG GRTGV VD V ++ F++ D+V +MR+QR VQT+EQY F
Sbjct: 349 MVVHCSAGIGRTGVFLCVDVVFCAIVKNC---SFNIMDIVAQMREQRSGMVQTKEQYHFC 405
Query: 285 YHTVAQM 291
Y V ++
Sbjct: 406 YDIVLEV 412
>gi|148728162 protein tyrosine phosphatase, receptor type, J isoform 1
precursor [Homo sapiens]
Length = 1337
Score = 164 bits (415), Expect = 2e-40
Identities = 103/276 (37%), Positives = 141/276 (51%), Gaps = 20/276 (7%)
Query: 50 AGSRPENVRKNRYKDVLPYDQTRVILSLLQEEGHSDYINGNFIRGVDGSLAYIATQGPLP 109
A EN KNRY +VLPYD +RV LS+ Q DYIN N++ G +IATQGPLP
Sbjct: 1059 AAELAENRGKNRYNNVLPYDISRVKLSV-QTHSTDDYINANYMPGYHSKKDFIATQGPLP 1117
Query: 110 HTLLDFWRLVWEFGVKVILMACREIENGRKRCERYWAQEQEPLQTGLFCITLIKE----K 165
+TL DFWR+VWE V I+M + +E GR +CE YW +Q G + + E +
Sbjct: 1118 NTLKDFWRMVWEKNVYAIIMLTKCVEQGRTKCEEYWPSKQAQ-DYGDITVAMTSEIVLPE 1176
Query: 166 WLNEDIMLRTLKVTFQKESRSVYQLQYMSWPDRGVPSSPDHMLAMVEEARRLQGSGP--E 223
W D ++ ++ + ES + Q + SWPD GVP + D ++ R P
Sbjct: 1177 WTIRDFTVKNIQTS---ESHPLRQFHFTSWPDHGVPDTTDLLINFRYLVRDYMKQSPPES 1233
Query: 224 PLCVHCSAGCGRTGVLCTVDYVRQLLLTQMIPPDFSLFDVVLKMRKQRPAAVQTEEQYRF 283
P+ VHCSAG GRTG +D +L+ ++ +V +R RP VQTE+QY F
Sbjct: 1234 PILVHCSAGVGRTGTFIAID---RLIYQIENENTVDVYGIVYDLRMHRPLMVQTEDQYVF 1290
Query: 284 LYHTVAQMFCSTLQN-ASPHYQN-----IKENCAPL 313
L V + S + YQN I EN AP+
Sbjct: 1291 LNQCVLDIVRSQKDSKVDLIYQNTTAMTIYENLAPV 1326
>gi|18450371 protein tyrosine phosphatase, receptor type, A isoform
2 precursor [Homo sapiens]
Length = 793
Score = 164 bits (414), Expect = 2e-40
Identities = 95/260 (36%), Positives = 144/260 (55%), Gaps = 13/260 (5%)
Query: 51 GSRPENVRKNRYKDVLPYDQTRVILSLLQEEGHSDYINGNFIRGVDGSLAYIATQGPLPH 110
G+ P N++KNR ++PY+ RVI+ + + E ++DY+N +FI G +YIA+QGPL H
Sbjct: 544 GNLPANMKKNRVLQIIPYEFNRVIIPVKRGEENTDYVNASFIDGYRQKDSYIASQGPLLH 603
Query: 111 TLLDFWRLVWEFGVKVILMACREIENGRKRCERYWAQEQEPLQTGLFCITLIKEKWLNED 170
T+ DFWR++WE+ I+M E G+++C +YW + + G + L KE+ E
Sbjct: 604 TIEDFWRMIWEWKSCSIVMLTELEERGQEKCAQYWPSD-GLVSYGDITVELKKEEEC-ES 661
Query: 171 IMLRTLKVTFQKE--SRSVYQLQYMSWPDRGVPSSPDHMLAMVEEA-RRLQGSGPEPLCV 227
+R L VT +E SR + Q + WP+ G+PS M++++ ++ Q SG P+ V
Sbjct: 662 YTVRDLLVTNTRENKSRQIRQFHFHGWPEVGIPSDGKGMISIIAAVQKQQQQSGNHPITV 721
Query: 228 HCSAGCGRTGVLCTVDYVRQLLLTQMIPPDFSLFDVVLKMRKQRPAAVQTEEQYRFLYHT 287
HCSAG GRTG C + V + + + I +F V +R QRP VQT EQY F Y
Sbjct: 722 HCSAGAGRTGTFCALSTVLERVKAEGI---LDVFQTVKSLRLQRPHMVQTLEQYEFCYKV 778
Query: 288 VAQMFCSTLQNASPHYQNIK 307
V + +A Y N K
Sbjct: 779 VQEYI-----DAFSDYANFK 793
Score = 149 bits (376), Expect = 5e-36
Identities = 86/284 (30%), Positives = 142/284 (50%), Gaps = 13/284 (4%)
Query: 13 ERLEARGGREGAVLAGEFSDIQACSAAWKADGVCSTVAGSRPENVRKNRYKDVLPYDQTR 72
E + R + + EF+ + AC C A S+ EN KNRY ++LPYD +R
Sbjct: 219 EEINRRMADDNKLFREEFNALPACPI----QATCE--AASKEENKEKNRYVNILPYDHSR 272
Query: 73 VILSLLQEEGHSDYINGNFIRGVDGSLAYIATQGPLPHTLLDFWRLVWEFGVKVILMACR 132
V L+ ++ SDYIN +FI G +IA QGP T+ DFWR++WE I+M
Sbjct: 273 VHLTPVEGVPDSDYINASFINGYQEKNKFIAAQGPKEETVNDFWRMIWEQNTATIVMVTN 332
Query: 133 EIENGRKRCERYWAQE----QEPLQTGLFCITLIKEKWLNEDIMLRTLKVTFQKESRSVY 188
E +C +YW + ++ + +T++ + + + + + +T +K R +
Sbjct: 333 LKERKECKCAQYWPDQGCWTYGNIRVSVEDVTVLVDYTVRKFCIQQVGDMTNRKPQRLIT 392
Query: 189 QLQYMSWPDRGVPSSPDHMLAMVEEARRLQGSGPEPLCVHCSAGCGRTGVLCTVDYVRQL 248
Q + SWPD GVP +P ML +++ + + VHCSAG GRTG +D + +
Sbjct: 393 QFHFTSWPDFGVPFTPIGMLKFLKKVKACNPQYAGAIVVHCSAGVGRTGTFVVIDAMLDM 452
Query: 249 LLTQMIPPDFSLFDVVLKMRKQRPAAVQTEEQYRFLYHTVAQMF 292
+ T+ ++ V ++R QR VQT+ QY F+Y + + +
Sbjct: 453 MHTER---KVDVYGFVSRIRAQRCQMVQTDMQYVFIYQALLEHY 493
>gi|4506303 protein tyrosine phosphatase, receptor type, A isoform 1
precursor [Homo sapiens]
Length = 802
Score = 164 bits (414), Expect = 2e-40
Identities = 95/260 (36%), Positives = 144/260 (55%), Gaps = 13/260 (5%)
Query: 51 GSRPENVRKNRYKDVLPYDQTRVILSLLQEEGHSDYINGNFIRGVDGSLAYIATQGPLPH 110
G+ P N++KNR ++PY+ RVI+ + + E ++DY+N +FI G +YIA+QGPL H
Sbjct: 553 GNLPANMKKNRVLQIIPYEFNRVIIPVKRGEENTDYVNASFIDGYRQKDSYIASQGPLLH 612
Query: 111 TLLDFWRLVWEFGVKVILMACREIENGRKRCERYWAQEQEPLQTGLFCITLIKEKWLNED 170
T+ DFWR++WE+ I+M E G+++C +YW + + G + L KE+ E
Sbjct: 613 TIEDFWRMIWEWKSCSIVMLTELEERGQEKCAQYWPSD-GLVSYGDITVELKKEEEC-ES 670
Query: 171 IMLRTLKVTFQKE--SRSVYQLQYMSWPDRGVPSSPDHMLAMVEEA-RRLQGSGPEPLCV 227
+R L VT +E SR + Q + WP+ G+PS M++++ ++ Q SG P+ V
Sbjct: 671 YTVRDLLVTNTRENKSRQIRQFHFHGWPEVGIPSDGKGMISIIAAVQKQQQQSGNHPITV 730
Query: 228 HCSAGCGRTGVLCTVDYVRQLLLTQMIPPDFSLFDVVLKMRKQRPAAVQTEEQYRFLYHT 287
HCSAG GRTG C + V + + + I +F V +R QRP VQT EQY F Y
Sbjct: 731 HCSAGAGRTGTFCALSTVLERVKAEGI---LDVFQTVKSLRLQRPHMVQTLEQYEFCYKV 787
Query: 288 VAQMFCSTLQNASPHYQNIK 307
V + +A Y N K
Sbjct: 788 VQEYI-----DAFSDYANFK 802
Score = 149 bits (376), Expect = 5e-36
Identities = 86/284 (30%), Positives = 142/284 (50%), Gaps = 13/284 (4%)
Query: 13 ERLEARGGREGAVLAGEFSDIQACSAAWKADGVCSTVAGSRPENVRKNRYKDVLPYDQTR 72
E + R + + EF+ + AC C A S+ EN KNRY ++LPYD +R
Sbjct: 228 EEINRRMADDNKLFREEFNALPACPI----QATCE--AASKEENKEKNRYVNILPYDHSR 281
Query: 73 VILSLLQEEGHSDYINGNFIRGVDGSLAYIATQGPLPHTLLDFWRLVWEFGVKVILMACR 132
V L+ ++ SDYIN +FI G +IA QGP T+ DFWR++WE I+M
Sbjct: 282 VHLTPVEGVPDSDYINASFINGYQEKNKFIAAQGPKEETVNDFWRMIWEQNTATIVMVTN 341
Query: 133 EIENGRKRCERYWAQE----QEPLQTGLFCITLIKEKWLNEDIMLRTLKVTFQKESRSVY 188
E +C +YW + ++ + +T++ + + + + + +T +K R +
Sbjct: 342 LKERKECKCAQYWPDQGCWTYGNIRVSVEDVTVLVDYTVRKFCIQQVGDMTNRKPQRLIT 401
Query: 189 QLQYMSWPDRGVPSSPDHMLAMVEEARRLQGSGPEPLCVHCSAGCGRTGVLCTVDYVRQL 248
Q + SWPD GVP +P ML +++ + + VHCSAG GRTG +D + +
Sbjct: 402 QFHFTSWPDFGVPFTPIGMLKFLKKVKACNPQYAGAIVVHCSAGVGRTGTFVVIDAMLDM 461
Query: 249 LLTQMIPPDFSLFDVVLKMRKQRPAAVQTEEQYRFLYHTVAQMF 292
+ T+ ++ V ++R QR VQT+ QY F+Y + + +
Sbjct: 462 MHTER---KVDVYGFVSRIRAQRCQMVQTDMQYVFIYQALLEHY 502
>gi|18450369 protein tyrosine phosphatase, receptor type, A isoform
2 precursor [Homo sapiens]
Length = 793
Score = 164 bits (414), Expect = 2e-40
Identities = 95/260 (36%), Positives = 144/260 (55%), Gaps = 13/260 (5%)
Query: 51 GSRPENVRKNRYKDVLPYDQTRVILSLLQEEGHSDYINGNFIRGVDGSLAYIATQGPLPH 110
G+ P N++KNR ++PY+ RVI+ + + E ++DY+N +FI G +YIA+QGPL H
Sbjct: 544 GNLPANMKKNRVLQIIPYEFNRVIIPVKRGEENTDYVNASFIDGYRQKDSYIASQGPLLH 603
Query: 111 TLLDFWRLVWEFGVKVILMACREIENGRKRCERYWAQEQEPLQTGLFCITLIKEKWLNED 170
T+ DFWR++WE+ I+M E G+++C +YW + + G + L KE+ E
Sbjct: 604 TIEDFWRMIWEWKSCSIVMLTELEERGQEKCAQYWPSD-GLVSYGDITVELKKEEEC-ES 661
Query: 171 IMLRTLKVTFQKE--SRSVYQLQYMSWPDRGVPSSPDHMLAMVEEA-RRLQGSGPEPLCV 227
+R L VT +E SR + Q + WP+ G+PS M++++ ++ Q SG P+ V
Sbjct: 662 YTVRDLLVTNTRENKSRQIRQFHFHGWPEVGIPSDGKGMISIIAAVQKQQQQSGNHPITV 721
Query: 228 HCSAGCGRTGVLCTVDYVRQLLLTQMIPPDFSLFDVVLKMRKQRPAAVQTEEQYRFLYHT 287
HCSAG GRTG C + V + + + I +F V +R QRP VQT EQY F Y
Sbjct: 722 HCSAGAGRTGTFCALSTVLERVKAEGI---LDVFQTVKSLRLQRPHMVQTLEQYEFCYKV 778
Query: 288 VAQMFCSTLQNASPHYQNIK 307
V + +A Y N K
Sbjct: 779 VQEYI-----DAFSDYANFK 793
Score = 149 bits (376), Expect = 5e-36
Identities = 86/284 (30%), Positives = 142/284 (50%), Gaps = 13/284 (4%)
Query: 13 ERLEARGGREGAVLAGEFSDIQACSAAWKADGVCSTVAGSRPENVRKNRYKDVLPYDQTR 72
E + R + + EF+ + AC C A S+ EN KNRY ++LPYD +R
Sbjct: 219 EEINRRMADDNKLFREEFNALPACPI----QATCE--AASKEENKEKNRYVNILPYDHSR 272
Query: 73 VILSLLQEEGHSDYINGNFIRGVDGSLAYIATQGPLPHTLLDFWRLVWEFGVKVILMACR 132
V L+ ++ SDYIN +FI G +IA QGP T+ DFWR++WE I+M
Sbjct: 273 VHLTPVEGVPDSDYINASFINGYQEKNKFIAAQGPKEETVNDFWRMIWEQNTATIVMVTN 332
Query: 133 EIENGRKRCERYWAQE----QEPLQTGLFCITLIKEKWLNEDIMLRTLKVTFQKESRSVY 188
E +C +YW + ++ + +T++ + + + + + +T +K R +
Sbjct: 333 LKERKECKCAQYWPDQGCWTYGNIRVSVEDVTVLVDYTVRKFCIQQVGDMTNRKPQRLIT 392
Query: 189 QLQYMSWPDRGVPSSPDHMLAMVEEARRLQGSGPEPLCVHCSAGCGRTGVLCTVDYVRQL 248
Q + SWPD GVP +P ML +++ + + VHCSAG GRTG +D + +
Sbjct: 393 QFHFTSWPDFGVPFTPIGMLKFLKKVKACNPQYAGAIVVHCSAGVGRTGTFVVIDAMLDM 452
Query: 249 LLTQMIPPDFSLFDVVLKMRKQRPAAVQTEEQYRFLYHTVAQMF 292
+ T+ ++ V ++R QR VQT+ QY F+Y + + +
Sbjct: 453 MHTER---KVDVYGFVSRIRAQRCQMVQTDMQYVFIYQALLEHY 493
>gi|196114970 protein tyrosine phosphatase, non-receptor type 12
isoform 3 [Homo sapiens]
Length = 650
Score = 162 bits (411), Expect = 5e-40
Identities = 79/170 (46%), Positives = 110/170 (64%), Gaps = 2/170 (1%)
Query: 129 MACREIENGRKRCERYWA-QEQEPLQTGLFCITLIKEKWLNEDIMLRTLKVTFQKESRSV 187
MACRE E GRK+CERYW ++P+ F I+ E+ D +RTL + FQ ESR +
Sbjct: 1 MACREFEMGRKKCERYWPLYGEDPITFAPFKISCEDEQ-ARTDYFIRTLLLEFQNESRRL 59
Query: 188 YQLQYMSWPDRGVPSSPDHMLAMVEEARRLQGSGPEPLCVHCSAGCGRTGVLCTVDYVRQ 247
YQ Y++WPD VPSS D +L M+ R+ Q P+C+HCSAGCGRTG +C +DY
Sbjct: 60 YQFHYVNWPDHDVPSSFDSILDMISLMRKYQEHEDVPICIHCSAGCGRTGAICAIDYTWN 119
Query: 248 LLLTQMIPPDFSLFDVVLKMRKQRPAAVQTEEQYRFLYHTVAQMFCSTLQ 297
LL IP +F++F+++ +MR QR +AVQT+EQY ++ +AQ+F LQ
Sbjct: 120 LLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVHRAIAQLFEKQLQ 169
Score = 41.2 bits (95), Expect = 0.002
Identities = 15/21 (71%), Positives = 18/21 (85%)
Query: 438 LGFNLRIGRPKGPRDPPAEWT 458
+GF R G+PKGPRDPP+EWT
Sbjct: 630 IGFGNRCGKPKGPRDPPSEWT 650
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.135 0.417
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,857,108
Number of Sequences: 37866
Number of extensions: 1133659
Number of successful extensions: 5039
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 112
Number of HSP's successfully gapped in prelim test: 171
Number of HSP's that attempted gapping in prelim test: 4273
Number of HSP's gapped (non-prelim): 524
length of query: 460
length of database: 18,247,518
effective HSP length: 106
effective length of query: 354
effective length of database: 14,233,722
effective search space: 5038737588
effective search space used: 5038737588
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.