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Search of human proteins with 18375650
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|18375650 protein tyrosine phosphatase, non-receptor type 13
isoform 4 [Homo sapiens]
(2490 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|18375650 protein tyrosine phosphatase, non-receptor type 13 i... 4950 0.0
gi|18375646 protein tyrosine phosphatase, non-receptor type 13 i... 4935 0.0
gi|5453992 protein tyrosine phosphatase, non-receptor type 13 is... 4886 0.0
gi|18375648 protein tyrosine phosphatase, non-receptor type 13 i... 2814 0.0
gi|110346438 FERM and PDZ domain containing 2 isoform 1 [Homo sa... 297 8e-80
gi|110346436 FERM and PDZ domain containing 2 isoform 3 [Homo sa... 297 8e-80
gi|109138573 protein tyrosine phosphatase, non-receptor type 20A... 239 3e-62
gi|109138561 protein tyrosine phosphatase, non-receptor type 20A... 239 3e-62
gi|109138557 protein tyrosine phosphatase, non-receptor type 20A... 239 3e-62
gi|108802617 protein tyrosine phosphatase, non-receptor type 20 ... 239 3e-62
gi|108802607 protein tyrosine phosphatase, non-receptor type 20 ... 239 3e-62
gi|108802604 protein tyrosine phosphatase, non-receptor type 20 ... 239 3e-62
gi|108802611 protein tyrosine phosphatase, non-receptor type 20 ... 214 7e-55
gi|109138565 protein tyrosine phosphatase, non-receptor type 20A... 214 7e-55
gi|241896926 protein tyrosine phosphatase, receptor type, H isof... 194 1e-48
gi|241896924 protein tyrosine phosphatase, receptor type, H isof... 194 1e-48
gi|223941891 protein tyrosine phosphatase, non-receptor type 3 i... 190 2e-47
gi|223941888 protein tyrosine phosphatase, non-receptor type 3 i... 190 2e-47
gi|223941885 protein tyrosine phosphatase, non-receptor type 3 i... 190 2e-47
gi|223941882 protein tyrosine phosphatase, non-receptor type 3 i... 190 2e-47
gi|223941879 protein tyrosine phosphatase, non-receptor type 3 i... 190 2e-47
gi|223941876 protein tyrosine phosphatase, non-receptor type 3 i... 190 2e-47
gi|33356177 protein tyrosine phosphatase, non-receptor type 11 [... 189 3e-47
gi|4506295 protein tyrosine phosphatase, non-receptor type 4 [Ho... 186 2e-46
gi|109633041 protein tyrosine phosphatase, receptor type, F isof... 183 2e-45
gi|109633039 protein tyrosine phosphatase, receptor type, F isof... 183 2e-45
gi|208431815 protein tyrosine phosphatase, receptor type, K isof... 182 4e-45
gi|18104993 protein tyrosine phosphatase, non-receptor type 6 is... 182 4e-45
gi|18104989 protein tyrosine phosphatase, non-receptor type 6 is... 182 4e-45
gi|18104991 protein tyrosine phosphatase, non-receptor type 6 is... 182 4e-45
>gi|18375650 protein tyrosine phosphatase, non-receptor type 13
isoform 4 [Homo sapiens]
Length = 2490
Score = 4950 bits (12841), Expect = 0.0
Identities = 2490/2490 (100%), Positives = 2490/2490 (100%)
Query: 1 MHVSLAEALEVRGGPLQEEEIWAVLNQSAESLQELFRKVSLADPAALGFIISPWSLLLLP 60
MHVSLAEALEVRGGPLQEEEIWAVLNQSAESLQELFRKVSLADPAALGFIISPWSLLLLP
Sbjct: 1 MHVSLAEALEVRGGPLQEEEIWAVLNQSAESLQELFRKVSLADPAALGFIISPWSLLLLP 60
Query: 61 SGSVSFTDENISNQDLRAFTAPEVLQNQSLTSLSDVEKIHIYSLGMTLYWGADYEVPQSQ 120
SGSVSFTDENISNQDLRAFTAPEVLQNQSLTSLSDVEKIHIYSLGMTLYWGADYEVPQSQ
Sbjct: 61 SGSVSFTDENISNQDLRAFTAPEVLQNQSLTSLSDVEKIHIYSLGMTLYWGADYEVPQSQ 120
Query: 121 PIKLGDHLNSILLGMCEDVIYARVSVRTVLDACSAHIRNSNCAPSFSYVKHLVKLVLGNL 180
PIKLGDHLNSILLGMCEDVIYARVSVRTVLDACSAHIRNSNCAPSFSYVKHLVKLVLGNL
Sbjct: 121 PIKLGDHLNSILLGMCEDVIYARVSVRTVLDACSAHIRNSNCAPSFSYVKHLVKLVLGNL 180
Query: 181 SGTDQLSCNSEQKPDRSQAIRDRLRGKGLPTGRSSTSDVLDIQKPPLSHQTFLNKGLSKS 240
SGTDQLSCNSEQKPDRSQAIRDRLRGKGLPTGRSSTSDVLDIQKPPLSHQTFLNKGLSKS
Sbjct: 181 SGTDQLSCNSEQKPDRSQAIRDRLRGKGLPTGRSSTSDVLDIQKPPLSHQTFLNKGLSKS 240
Query: 241 MGFLSIKDTQDENYFKDILSDNSGREDSENTFSPYQFKTSGPEKKPIPGIDVLSKKKIWA 300
MGFLSIKDTQDENYFKDILSDNSGREDSENTFSPYQFKTSGPEKKPIPGIDVLSKKKIWA
Sbjct: 241 MGFLSIKDTQDENYFKDILSDNSGREDSENTFSPYQFKTSGPEKKPIPGIDVLSKKKIWA 300
Query: 301 SSMDLLCTADRDFSSGETATYRRCHPEAVTVRTSTTPRKKEARYSDGSIALDIFGPQKMD 360
SSMDLLCTADRDFSSGETATYRRCHPEAVTVRTSTTPRKKEARYSDGSIALDIFGPQKMD
Sbjct: 301 SSMDLLCTADRDFSSGETATYRRCHPEAVTVRTSTTPRKKEARYSDGSIALDIFGPQKMD 360
Query: 361 PIYHTRELPTSSAISSALDRIRERQKKLQVLREAMNVEEPVRRYKTYHGDVFSTSSESPS 420
PIYHTRELPTSSAISSALDRIRERQKKLQVLREAMNVEEPVRRYKTYHGDVFSTSSESPS
Sbjct: 361 PIYHTRELPTSSAISSALDRIRERQKKLQVLREAMNVEEPVRRYKTYHGDVFSTSSESPS 420
Query: 421 IISSESDFRQVRRSEASKRFESSSGLPGVDETLSQGQSQRPSRQYETPFEGNLINQEIML 480
IISSESDFRQVRRSEASKRFESSSGLPGVDETLSQGQSQRPSRQYETPFEGNLINQEIML
Sbjct: 421 IISSESDFRQVRRSEASKRFESSSGLPGVDETLSQGQSQRPSRQYETPFEGNLINQEIML 480
Query: 481 KRQEEELMQLQAKMALRQSRLSLYPGDTIKASMLDITRDPLREIALETAMTQRKLRNFFG 540
KRQEEELMQLQAKMALRQSRLSLYPGDTIKASMLDITRDPLREIALETAMTQRKLRNFFG
Sbjct: 481 KRQEEELMQLQAKMALRQSRLSLYPGDTIKASMLDITRDPLREIALETAMTQRKLRNFFG 540
Query: 541 PEFVKMTIEPFISLDLPRSILTKKGKNEDNRRKVNIMLLNGQRLELTCDTKTICKDVFDM 600
PEFVKMTIEPFISLDLPRSILTKKGKNEDNRRKVNIMLLNGQRLELTCDTKTICKDVFDM
Sbjct: 541 PEFVKMTIEPFISLDLPRSILTKKGKNEDNRRKVNIMLLNGQRLELTCDTKTICKDVFDM 600
Query: 601 VVAHIGLVEHHLFALATLKDNEYFFVDPDLKLTKVAPEGWKEEPKKKTKATVNFTLFFRI 660
VVAHIGLVEHHLFALATLKDNEYFFVDPDLKLTKVAPEGWKEEPKKKTKATVNFTLFFRI
Sbjct: 601 VVAHIGLVEHHLFALATLKDNEYFFVDPDLKLTKVAPEGWKEEPKKKTKATVNFTLFFRI 660
Query: 661 KFFMDDVSLIQHTLTCHQYYLQLRKDILEERMHCDDETSLLLASLALQAEYGDYQPEVHG 720
KFFMDDVSLIQHTLTCHQYYLQLRKDILEERMHCDDETSLLLASLALQAEYGDYQPEVHG
Sbjct: 661 KFFMDDVSLIQHTLTCHQYYLQLRKDILEERMHCDDETSLLLASLALQAEYGDYQPEVHG 720
Query: 721 VSYFRMEHYLPARVMEKLDLSYIKEELPKLHNTYVGASEKETELEFLKVCQRLTEYGVHF 780
VSYFRMEHYLPARVMEKLDLSYIKEELPKLHNTYVGASEKETELEFLKVCQRLTEYGVHF
Sbjct: 721 VSYFRMEHYLPARVMEKLDLSYIKEELPKLHNTYVGASEKETELEFLKVCQRLTEYGVHF 780
Query: 781 HRVHPEKKSQTGILLGVCSKGVLVFEVHNGVRTLVLRFPWRETKKISFSKKKITLQNTSD 840
HRVHPEKKSQTGILLGVCSKGVLVFEVHNGVRTLVLRFPWRETKKISFSKKKITLQNTSD
Sbjct: 781 HRVHPEKKSQTGILLGVCSKGVLVFEVHNGVRTLVLRFPWRETKKISFSKKKITLQNTSD 840
Query: 841 GIKHGFQTDNSKICQYLLHLCSYQHKFQLQMRARQSNQDAQDIERASFRSLNLQAESVRG 900
GIKHGFQTDNSKICQYLLHLCSYQHKFQLQMRARQSNQDAQDIERASFRSLNLQAESVRG
Sbjct: 841 GIKHGFQTDNSKICQYLLHLCSYQHKFQLQMRARQSNQDAQDIERASFRSLNLQAESVRG 900
Query: 901 FNMGRAISTGSLASSTLNKLAVRPLSVQAEILKRLSCSELSLYQPLQNSSKEKNDKASWE 960
FNMGRAISTGSLASSTLNKLAVRPLSVQAEILKRLSCSELSLYQPLQNSSKEKNDKASWE
Sbjct: 901 FNMGRAISTGSLASSTLNKLAVRPLSVQAEILKRLSCSELSLYQPLQNSSKEKNDKASWE 960
Query: 961 EKPREMSKSYHDLSQASLYPHRKNVIVNMEPPPQTVAELVGKPSHQMSRSDAESLAGVTK 1020
EKPREMSKSYHDLSQASLYPHRKNVIVNMEPPPQTVAELVGKPSHQMSRSDAESLAGVTK
Sbjct: 961 EKPREMSKSYHDLSQASLYPHRKNVIVNMEPPPQTVAELVGKPSHQMSRSDAESLAGVTK 1020
Query: 1021 LNNSKSVASLNRSPERRKHESDSSSIEDPGQAYVLGMTMHSSGNSSSQVPLKENDVLHKR 1080
LNNSKSVASLNRSPERRKHESDSSSIEDPGQAYVLGMTMHSSGNSSSQVPLKENDVLHKR
Sbjct: 1021 LNNSKSVASLNRSPERRKHESDSSSIEDPGQAYVLGMTMHSSGNSSSQVPLKENDVLHKR 1080
Query: 1081 WSIVSSPEREITLVNLKKDAKYGLGFQIIGGEKMGRLDLGIFISSVAPGGPADLDGCLKP 1140
WSIVSSPEREITLVNLKKDAKYGLGFQIIGGEKMGRLDLGIFISSVAPGGPADLDGCLKP
Sbjct: 1081 WSIVSSPEREITLVNLKKDAKYGLGFQIIGGEKMGRLDLGIFISSVAPGGPADLDGCLKP 1140
Query: 1141 GDRLISVNSVSLEGVSHHAAIEILQNAPEDVTLVISQPKEKISKVPSTPVHLTNEMKNYM 1200
GDRLISVNSVSLEGVSHHAAIEILQNAPEDVTLVISQPKEKISKVPSTPVHLTNEMKNYM
Sbjct: 1141 GDRLISVNSVSLEGVSHHAAIEILQNAPEDVTLVISQPKEKISKVPSTPVHLTNEMKNYM 1200
Query: 1201 KKSSYMQDSAIDSSSKDHHWSRGTLRHISENSFGPSGGLREGSLSSQDSRTESASLSQSQ 1260
KKSSYMQDSAIDSSSKDHHWSRGTLRHISENSFGPSGGLREGSLSSQDSRTESASLSQSQ
Sbjct: 1201 KKSSYMQDSAIDSSSKDHHWSRGTLRHISENSFGPSGGLREGSLSSQDSRTESASLSQSQ 1260
Query: 1261 VNGFFASHLGDQTWQESQHGSPSPSVISKATEKETFTDSNQSKTKKPGISDVTDYSDRGD 1320
VNGFFASHLGDQTWQESQHGSPSPSVISKATEKETFTDSNQSKTKKPGISDVTDYSDRGD
Sbjct: 1261 VNGFFASHLGDQTWQESQHGSPSPSVISKATEKETFTDSNQSKTKKPGISDVTDYSDRGD 1320
Query: 1321 SDMDEATYSSSQDHQTPKQESSSSVNTSNKMNFKTFSSSPPKPGDIFEVELAKNDNSLGI 1380
SDMDEATYSSSQDHQTPKQESSSSVNTSNKMNFKTFSSSPPKPGDIFEVELAKNDNSLGI
Sbjct: 1321 SDMDEATYSSSQDHQTPKQESSSSVNTSNKMNFKTFSSSPPKPGDIFEVELAKNDNSLGI 1380
Query: 1381 SVTVLFDKGGVNTSVRHGGIYVKAVIPQGAAESDGRIHKGDRVLAVNGVSLEGATHKQAV 1440
SVTVLFDKGGVNTSVRHGGIYVKAVIPQGAAESDGRIHKGDRVLAVNGVSLEGATHKQAV
Sbjct: 1381 SVTVLFDKGGVNTSVRHGGIYVKAVIPQGAAESDGRIHKGDRVLAVNGVSLEGATHKQAV 1440
Query: 1441 ETLRNTGQVVHLLLEKGQSPTSKEHVPVTPQCTLSDQNAQGQGPEKVKKTTQVKDYSFVT 1500
ETLRNTGQVVHLLLEKGQSPTSKEHVPVTPQCTLSDQNAQGQGPEKVKKTTQVKDYSFVT
Sbjct: 1441 ETLRNTGQVVHLLLEKGQSPTSKEHVPVTPQCTLSDQNAQGQGPEKVKKTTQVKDYSFVT 1500
Query: 1501 EENTFEVKLFKNSSGLGFSFSREDNLIPEQINASIVRVKKLFPGQPAAESGKIDVGDVIL 1560
EENTFEVKLFKNSSGLGFSFSREDNLIPEQINASIVRVKKLFPGQPAAESGKIDVGDVIL
Sbjct: 1501 EENTFEVKLFKNSSGLGFSFSREDNLIPEQINASIVRVKKLFPGQPAAESGKIDVGDVIL 1560
Query: 1561 KVNGASLKGLSQQEVISALRGTAPEVFLLLCRPPPGVLPEIDTALLTPLQSPAQVLPNSS 1620
KVNGASLKGLSQQEVISALRGTAPEVFLLLCRPPPGVLPEIDTALLTPLQSPAQVLPNSS
Sbjct: 1561 KVNGASLKGLSQQEVISALRGTAPEVFLLLCRPPPGVLPEIDTALLTPLQSPAQVLPNSS 1620
Query: 1621 KDSSQPSCVEQSTSSDENEMSDKSKKQCKSPSRRDSYSDSSGSGEDDLVTAPANISNSTW 1680
KDSSQPSCVEQSTSSDENEMSDKSKKQCKSPSRRDSYSDSSGSGEDDLVTAPANISNSTW
Sbjct: 1621 KDSSQPSCVEQSTSSDENEMSDKSKKQCKSPSRRDSYSDSSGSGEDDLVTAPANISNSTW 1680
Query: 1681 SSALHQTLSNMVSQAQSHHEAPKSQEDTICTMFYYPQKIPNKPEFEDSNPSPLPPDMAPG 1740
SSALHQTLSNMVSQAQSHHEAPKSQEDTICTMFYYPQKIPNKPEFEDSNPSPLPPDMAPG
Sbjct: 1681 SSALHQTLSNMVSQAQSHHEAPKSQEDTICTMFYYPQKIPNKPEFEDSNPSPLPPDMAPG 1740
Query: 1741 QSYQPQSESASSSSMDKYHIHHISEPTRQENWTPLKNDLENHLEDFELEVELLITLIKSE 1800
QSYQPQSESASSSSMDKYHIHHISEPTRQENWTPLKNDLENHLEDFELEVELLITLIKSE
Sbjct: 1741 QSYQPQSESASSSSMDKYHIHHISEPTRQENWTPLKNDLENHLEDFELEVELLITLIKSE 1800
Query: 1801 KGSLGFTVTKGNQRIGCYVHDVIQDPAKSDGRLKPGDRLIKVNDTDVTNMTHTDAVNLLR 1860
KGSLGFTVTKGNQRIGCYVHDVIQDPAKSDGRLKPGDRLIKVNDTDVTNMTHTDAVNLLR
Sbjct: 1801 KGSLGFTVTKGNQRIGCYVHDVIQDPAKSDGRLKPGDRLIKVNDTDVTNMTHTDAVNLLR 1860
Query: 1861 AASKTVRLVIGRVLELPRIPMLPHLLPDITLTCNKEELGFSLCGGHDSLYQVVYISDINP 1920
AASKTVRLVIGRVLELPRIPMLPHLLPDITLTCNKEELGFSLCGGHDSLYQVVYISDINP
Sbjct: 1861 AASKTVRLVIGRVLELPRIPMLPHLLPDITLTCNKEELGFSLCGGHDSLYQVVYISDINP 1920
Query: 1921 RSVAAIEGNLQLLDVIHYVNGVSTQGMTLEEVNRALDMSLPSLVLKATRNDLPVVPSSKR 1980
RSVAAIEGNLQLLDVIHYVNGVSTQGMTLEEVNRALDMSLPSLVLKATRNDLPVVPSSKR
Sbjct: 1921 RSVAAIEGNLQLLDVIHYVNGVSTQGMTLEEVNRALDMSLPSLVLKATRNDLPVVPSSKR 1980
Query: 1981 SAVSAPKSTKGNGSYSVGSCSQPALTPNDSFSTVAGEEINEISYPKGKCSTYQIKGSPNL 2040
SAVSAPKSTKGNGSYSVGSCSQPALTPNDSFSTVAGEEINEISYPKGKCSTYQIKGSPNL
Sbjct: 1981 SAVSAPKSTKGNGSYSVGSCSQPALTPNDSFSTVAGEEINEISYPKGKCSTYQIKGSPNL 2040
Query: 2041 TLPKESYIQEDDIYDDSQEAEVIQSLLDVVDEEAQNLLNENNAAGYSCGPGTLKMNGKLS 2100
TLPKESYIQEDDIYDDSQEAEVIQSLLDVVDEEAQNLLNENNAAGYSCGPGTLKMNGKLS
Sbjct: 2041 TLPKESYIQEDDIYDDSQEAEVIQSLLDVVDEEAQNLLNENNAAGYSCGPGTLKMNGKLS 2100
Query: 2101 EERTEDTDCDGSPLPEYFTEATKMNGCEEYCEEKVKSESLIQKPQEKKTDDDEITWGNDE 2160
EERTEDTDCDGSPLPEYFTEATKMNGCEEYCEEKVKSESLIQKPQEKKTDDDEITWGNDE
Sbjct: 2101 EERTEDTDCDGSPLPEYFTEATKMNGCEEYCEEKVKSESLIQKPQEKKTDDDEITWGNDE 2160
Query: 2161 LPIERTNHEDSDKDHSFLTNDELAVLPVVKVLPSGKYTGANLKSVIRVLRGLLDQGIPSK 2220
LPIERTNHEDSDKDHSFLTNDELAVLPVVKVLPSGKYTGANLKSVIRVLRGLLDQGIPSK
Sbjct: 2161 LPIERTNHEDSDKDHSFLTNDELAVLPVVKVLPSGKYTGANLKSVIRVLRGLLDQGIPSK 2220
Query: 2221 ELENLQELKPLDQCLIGQTKENRRKNRYKNILPYDATRVPLGDEGGYINASFIKIPVGKE 2280
ELENLQELKPLDQCLIGQTKENRRKNRYKNILPYDATRVPLGDEGGYINASFIKIPVGKE
Sbjct: 2221 ELENLQELKPLDQCLIGQTKENRRKNRYKNILPYDATRVPLGDEGGYINASFIKIPVGKE 2280
Query: 2281 EFVYIACQGPLPTTVGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSN 2340
EFVYIACQGPLPTTVGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSN
Sbjct: 2281 EFVYIACQGPLPTTVGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSN 2340
Query: 2341 RLRLALVRMQQLKGFVVRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYM 2400
RLRLALVRMQQLKGFVVRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYM
Sbjct: 2341 RLRLALVRMQQLKGFVVRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYM 2400
Query: 2401 RHIHRSGPIITHCSAGIGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTED 2460
RHIHRSGPIITHCSAGIGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTED
Sbjct: 2401 RHIHRSGPIITHCSAGIGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTED 2460
Query: 2461 QYIFCYQVILYVLTRLQAEEEQKQQPQLLK 2490
QYIFCYQVILYVLTRLQAEEEQKQQPQLLK
Sbjct: 2461 QYIFCYQVILYVLTRLQAEEEQKQQPQLLK 2490
>gi|18375646 protein tyrosine phosphatase, non-receptor type 13
isoform 1 [Homo sapiens]
Length = 2485
Score = 4935 bits (12800), Expect = 0.0
Identities = 2485/2490 (99%), Positives = 2485/2490 (99%), Gaps = 5/2490 (0%)
Query: 1 MHVSLAEALEVRGGPLQEEEIWAVLNQSAESLQELFRKVSLADPAALGFIISPWSLLLLP 60
MHVSLAEALEVRGGPLQEEEIWAVLNQSAESLQELFRKVSLADPAALGFIISPWSLLLLP
Sbjct: 1 MHVSLAEALEVRGGPLQEEEIWAVLNQSAESLQELFRKVSLADPAALGFIISPWSLLLLP 60
Query: 61 SGSVSFTDENISNQDLRAFTAPEVLQNQSLTSLSDVEKIHIYSLGMTLYWGADYEVPQSQ 120
SGSVSFTDENISNQDLRAFTAPEVLQNQSLTSLSDVEKIHIYSLGMTLYWGADYEVPQSQ
Sbjct: 61 SGSVSFTDENISNQDLRAFTAPEVLQNQSLTSLSDVEKIHIYSLGMTLYWGADYEVPQSQ 120
Query: 121 PIKLGDHLNSILLGMCEDVIYARVSVRTVLDACSAHIRNSNCAPSFSYVKHLVKLVLGNL 180
PIKLGDHLNSILLGMCEDVIYARVSVRTVLDACSAHIRNSNCAPSFSYVKHLVKLVLGNL
Sbjct: 121 PIKLGDHLNSILLGMCEDVIYARVSVRTVLDACSAHIRNSNCAPSFSYVKHLVKLVLGNL 180
Query: 181 SGTDQLSCNSEQKPDRSQAIRDRLRGKGLPTGRSSTSDVLDIQKPPLSHQTFLNKGLSKS 240
SGTDQLSCNSEQKPDRSQAIRDRLRGKGLPTGRSSTSDVLDIQKPPLSHQTFLNKGLSKS
Sbjct: 181 SGTDQLSCNSEQKPDRSQAIRDRLRGKGLPTGRSSTSDVLDIQKPPLSHQTFLNKGLSKS 240
Query: 241 MGFLSIKDTQDENYFKDILSDNSGREDSENTFSPYQFKTSGPEKKPIPGIDVLSKKKIWA 300
MGFLSIKDTQDENYFKDILSDNSGREDSENTFSPYQFKTSGPEKKPIPGIDVLSKKKIWA
Sbjct: 241 MGFLSIKDTQDENYFKDILSDNSGREDSENTFSPYQFKTSGPEKKPIPGIDVLSKKKIWA 300
Query: 301 SSMDLLCTADRDFSSGETATYRRCHPEAVTVRTSTTPRKKEARYSDGSIALDIFGPQKMD 360
SSMDLLCTADRDFSSGETATYRRCHPEAVTVRTSTTPRKKEARYSDGSIALDIFGPQKMD
Sbjct: 301 SSMDLLCTADRDFSSGETATYRRCHPEAVTVRTSTTPRKKEARYSDGSIALDIFGPQKMD 360
Query: 361 PIYHTRELPTSSAISSALDRIRERQKKLQVLREAMNVEEPVRRYKTYHGDVFSTSSESPS 420
PIYHTRELPTSSAISSALDRIRERQKKLQVLREAMNVEEPVRRYKTYHGDVFSTSSESPS
Sbjct: 361 PIYHTRELPTSSAISSALDRIRERQKKLQVLREAMNVEEPVRRYKTYHGDVFSTSSESPS 420
Query: 421 IISSESDFRQVRRSEASKRFESSSGLPGVDETLSQGQSQRPSRQYETPFEGNLINQEIML 480
IISSESDFRQVRRSEASKRFESSSGLPGVDETLSQGQSQRPSRQYETPFEGNLINQEIML
Sbjct: 421 IISSESDFRQVRRSEASKRFESSSGLPGVDETLSQGQSQRPSRQYETPFEGNLINQEIML 480
Query: 481 KRQEEELMQLQAKMALRQSRLSLYPGDTIKASMLDITRDPLREIALETAMTQRKLRNFFG 540
KRQEEELMQLQAKMALRQSRLSLYPGDTIKASMLDITRDPLREIALETAMTQRKLRNFFG
Sbjct: 481 KRQEEELMQLQAKMALRQSRLSLYPGDTIKASMLDITRDPLREIALETAMTQRKLRNFFG 540
Query: 541 PEFVKMTIEPFISLDLPRSILTKKGKNEDNRRKVNIMLLNGQRLELTCDTKTICKDVFDM 600
PEFVKMTIEPFISLDLPRSILTKKGKNEDNRRKVNIMLLNGQRLELTCDTKTICKDVFDM
Sbjct: 541 PEFVKMTIEPFISLDLPRSILTKKGKNEDNRRKVNIMLLNGQRLELTCDTKTICKDVFDM 600
Query: 601 VVAHIGLVEHHLFALATLKDNEYFFVDPDLKLTKVAPEGWKEEPKKKTKATVNFTLFFRI 660
VVAHIGLVEHHLFALATLKDNEYFFVDPDLKLTKVAPEGWKEEPKKKTKATVNFTLFFRI
Sbjct: 601 VVAHIGLVEHHLFALATLKDNEYFFVDPDLKLTKVAPEGWKEEPKKKTKATVNFTLFFRI 660
Query: 661 KFFMDDVSLIQHTLTCHQYYLQLRKDILEERMHCDDETSLLLASLALQAEYGDYQPEVHG 720
KFFMDDVSLIQHTLTCHQYYLQLRKDILEERMHCDDETSLLLASLALQAEYGDYQPEVHG
Sbjct: 661 KFFMDDVSLIQHTLTCHQYYLQLRKDILEERMHCDDETSLLLASLALQAEYGDYQPEVHG 720
Query: 721 VSYFRMEHYLPARVMEKLDLSYIKEELPKLHNTYVGASEKETELEFLKVCQRLTEYGVHF 780
VSYFRMEHYLPARVMEKLDLSYIKEELPKLHNTYVGASEKETELEFLKVCQRLTEYGVHF
Sbjct: 721 VSYFRMEHYLPARVMEKLDLSYIKEELPKLHNTYVGASEKETELEFLKVCQRLTEYGVHF 780
Query: 781 HRVHPEKKSQTGILLGVCSKGVLVFEVHNGVRTLVLRFPWRETKKISFSKKKITLQNTSD 840
HRVHPEKKSQTGILLGVCSKGVLVFEVHNGVRTLVLRFPWRETKKISFSKKKITLQNTSD
Sbjct: 781 HRVHPEKKSQTGILLGVCSKGVLVFEVHNGVRTLVLRFPWRETKKISFSKKKITLQNTSD 840
Query: 841 GIKHGFQTDNSKICQYLLHLCSYQHKFQLQMRARQSNQDAQDIERASFRSLNLQAESVRG 900
GIKHGFQTDNSKICQYLLHLCSYQHKFQLQMRARQSNQDAQDIERASFRSLNLQAESVRG
Sbjct: 841 GIKHGFQTDNSKICQYLLHLCSYQHKFQLQMRARQSNQDAQDIERASFRSLNLQAESVRG 900
Query: 901 FNMGRAISTGSLASSTLNKLAVRPLSVQAEILKRLSCSELSLYQPLQNSSKEKNDKASWE 960
FNMGRAISTGSLASSTLNKLAVRPLSVQAEILKRLSCSELSLYQPLQNSSKEKNDKASWE
Sbjct: 901 FNMGRAISTGSLASSTLNKLAVRPLSVQAEILKRLSCSELSLYQPLQNSSKEKNDKASWE 960
Query: 961 EKPREMSKSYHDLSQASLYPHRKNVIVNMEPPPQTVAELVGKPSHQMSRSDAESLAGVTK 1020
EKPREMSKSYHDLSQASLYPHRKNVIVNMEPPPQTVAELVGKPSHQMSRSDAESLAGVTK
Sbjct: 961 EKPREMSKSYHDLSQASLYPHRKNVIVNMEPPPQTVAELVGKPSHQMSRSDAESLAGVTK 1020
Query: 1021 LNNSKSVASLNRSPERRKHESDSSSIEDPGQAYVLGMTMHSSGNSSSQVPLKENDVLHKR 1080
LNNSKSVASLNRSPERRKHESDSSSIEDPGQAYVLGMTMHSSGNSSSQVPLKENDVLHKR
Sbjct: 1021 LNNSKSVASLNRSPERRKHESDSSSIEDPGQAYVLGMTMHSSGNSSSQVPLKENDVLHKR 1080
Query: 1081 WSIVSSPEREITLVNLKKDAKYGLGFQIIGGEKMGRLDLGIFISSVAPGGPADLDGCLKP 1140
WSIVSSPEREITLVNLKKDAKYGLGFQIIGGEKMGRLDLGIFISSVAPGGPADLDGCLKP
Sbjct: 1081 WSIVSSPEREITLVNLKKDAKYGLGFQIIGGEKMGRLDLGIFISSVAPGGPADLDGCLKP 1140
Query: 1141 GDRLISVNSVSLEGVSHHAAIEILQNAPEDVTLVISQPKEKISKVPSTPVHLTNEMKNYM 1200
GDRLISVNSVSLEGVSHHAAIEILQNAPEDVTLVISQPKEKISKVPSTPVHLTNEMKNYM
Sbjct: 1141 GDRLISVNSVSLEGVSHHAAIEILQNAPEDVTLVISQPKEKISKVPSTPVHLTNEMKNYM 1200
Query: 1201 KKSSYMQDSAIDSSSKDHHWSRGTLRHISENSFGPSGGLREGSLSSQDSRTESASLSQSQ 1260
KKSSYMQDSAIDSSSKDHHWSRGTLRHISENSFGPSGGLREGSLSSQDSRTESASLSQSQ
Sbjct: 1201 KKSSYMQDSAIDSSSKDHHWSRGTLRHISENSFGPSGGLREGSLSSQDSRTESASLSQSQ 1260
Query: 1261 VNGFFASHLGDQTWQESQHGSPSPSVISKATEKETFTDSNQSKTKKPGISDVTDYSDRGD 1320
VNGFFASHLGDQTWQESQHGSPSPSVISKATEKETFTDSNQSKTKKPGISDVTDYSDRGD
Sbjct: 1261 VNGFFASHLGDQTWQESQHGSPSPSVISKATEKETFTDSNQSKTKKPGISDVTDYSDRGD 1320
Query: 1321 SDMDEATYSSSQDHQTPKQESSSSVNTSNKMNFKTFSSSPPKPGDIFEVELAKNDNSLGI 1380
SDMDEATYSSSQDHQTPKQESSSSVNTSNKMNFKTFSSSPPKPGDIFEVELAKNDNSLGI
Sbjct: 1321 SDMDEATYSSSQDHQTPKQESSSSVNTSNKMNFKTFSSSPPKPGDIFEVELAKNDNSLGI 1380
Query: 1381 SVTVLFDKGGVNTSVRHGGIYVKAVIPQGAAESDGRIHKGDRVLAVNGVSLEGATHKQAV 1440
SVT GGVNTSVRHGGIYVKAVIPQGAAESDGRIHKGDRVLAVNGVSLEGATHKQAV
Sbjct: 1381 SVT-----GGVNTSVRHGGIYVKAVIPQGAAESDGRIHKGDRVLAVNGVSLEGATHKQAV 1435
Query: 1441 ETLRNTGQVVHLLLEKGQSPTSKEHVPVTPQCTLSDQNAQGQGPEKVKKTTQVKDYSFVT 1500
ETLRNTGQVVHLLLEKGQSPTSKEHVPVTPQCTLSDQNAQGQGPEKVKKTTQVKDYSFVT
Sbjct: 1436 ETLRNTGQVVHLLLEKGQSPTSKEHVPVTPQCTLSDQNAQGQGPEKVKKTTQVKDYSFVT 1495
Query: 1501 EENTFEVKLFKNSSGLGFSFSREDNLIPEQINASIVRVKKLFPGQPAAESGKIDVGDVIL 1560
EENTFEVKLFKNSSGLGFSFSREDNLIPEQINASIVRVKKLFPGQPAAESGKIDVGDVIL
Sbjct: 1496 EENTFEVKLFKNSSGLGFSFSREDNLIPEQINASIVRVKKLFPGQPAAESGKIDVGDVIL 1555
Query: 1561 KVNGASLKGLSQQEVISALRGTAPEVFLLLCRPPPGVLPEIDTALLTPLQSPAQVLPNSS 1620
KVNGASLKGLSQQEVISALRGTAPEVFLLLCRPPPGVLPEIDTALLTPLQSPAQVLPNSS
Sbjct: 1556 KVNGASLKGLSQQEVISALRGTAPEVFLLLCRPPPGVLPEIDTALLTPLQSPAQVLPNSS 1615
Query: 1621 KDSSQPSCVEQSTSSDENEMSDKSKKQCKSPSRRDSYSDSSGSGEDDLVTAPANISNSTW 1680
KDSSQPSCVEQSTSSDENEMSDKSKKQCKSPSRRDSYSDSSGSGEDDLVTAPANISNSTW
Sbjct: 1616 KDSSQPSCVEQSTSSDENEMSDKSKKQCKSPSRRDSYSDSSGSGEDDLVTAPANISNSTW 1675
Query: 1681 SSALHQTLSNMVSQAQSHHEAPKSQEDTICTMFYYPQKIPNKPEFEDSNPSPLPPDMAPG 1740
SSALHQTLSNMVSQAQSHHEAPKSQEDTICTMFYYPQKIPNKPEFEDSNPSPLPPDMAPG
Sbjct: 1676 SSALHQTLSNMVSQAQSHHEAPKSQEDTICTMFYYPQKIPNKPEFEDSNPSPLPPDMAPG 1735
Query: 1741 QSYQPQSESASSSSMDKYHIHHISEPTRQENWTPLKNDLENHLEDFELEVELLITLIKSE 1800
QSYQPQSESASSSSMDKYHIHHISEPTRQENWTPLKNDLENHLEDFELEVELLITLIKSE
Sbjct: 1736 QSYQPQSESASSSSMDKYHIHHISEPTRQENWTPLKNDLENHLEDFELEVELLITLIKSE 1795
Query: 1801 KGSLGFTVTKGNQRIGCYVHDVIQDPAKSDGRLKPGDRLIKVNDTDVTNMTHTDAVNLLR 1860
KGSLGFTVTKGNQRIGCYVHDVIQDPAKSDGRLKPGDRLIKVNDTDVTNMTHTDAVNLLR
Sbjct: 1796 KGSLGFTVTKGNQRIGCYVHDVIQDPAKSDGRLKPGDRLIKVNDTDVTNMTHTDAVNLLR 1855
Query: 1861 AASKTVRLVIGRVLELPRIPMLPHLLPDITLTCNKEELGFSLCGGHDSLYQVVYISDINP 1920
AASKTVRLVIGRVLELPRIPMLPHLLPDITLTCNKEELGFSLCGGHDSLYQVVYISDINP
Sbjct: 1856 AASKTVRLVIGRVLELPRIPMLPHLLPDITLTCNKEELGFSLCGGHDSLYQVVYISDINP 1915
Query: 1921 RSVAAIEGNLQLLDVIHYVNGVSTQGMTLEEVNRALDMSLPSLVLKATRNDLPVVPSSKR 1980
RSVAAIEGNLQLLDVIHYVNGVSTQGMTLEEVNRALDMSLPSLVLKATRNDLPVVPSSKR
Sbjct: 1916 RSVAAIEGNLQLLDVIHYVNGVSTQGMTLEEVNRALDMSLPSLVLKATRNDLPVVPSSKR 1975
Query: 1981 SAVSAPKSTKGNGSYSVGSCSQPALTPNDSFSTVAGEEINEISYPKGKCSTYQIKGSPNL 2040
SAVSAPKSTKGNGSYSVGSCSQPALTPNDSFSTVAGEEINEISYPKGKCSTYQIKGSPNL
Sbjct: 1976 SAVSAPKSTKGNGSYSVGSCSQPALTPNDSFSTVAGEEINEISYPKGKCSTYQIKGSPNL 2035
Query: 2041 TLPKESYIQEDDIYDDSQEAEVIQSLLDVVDEEAQNLLNENNAAGYSCGPGTLKMNGKLS 2100
TLPKESYIQEDDIYDDSQEAEVIQSLLDVVDEEAQNLLNENNAAGYSCGPGTLKMNGKLS
Sbjct: 2036 TLPKESYIQEDDIYDDSQEAEVIQSLLDVVDEEAQNLLNENNAAGYSCGPGTLKMNGKLS 2095
Query: 2101 EERTEDTDCDGSPLPEYFTEATKMNGCEEYCEEKVKSESLIQKPQEKKTDDDEITWGNDE 2160
EERTEDTDCDGSPLPEYFTEATKMNGCEEYCEEKVKSESLIQKPQEKKTDDDEITWGNDE
Sbjct: 2096 EERTEDTDCDGSPLPEYFTEATKMNGCEEYCEEKVKSESLIQKPQEKKTDDDEITWGNDE 2155
Query: 2161 LPIERTNHEDSDKDHSFLTNDELAVLPVVKVLPSGKYTGANLKSVIRVLRGLLDQGIPSK 2220
LPIERTNHEDSDKDHSFLTNDELAVLPVVKVLPSGKYTGANLKSVIRVLRGLLDQGIPSK
Sbjct: 2156 LPIERTNHEDSDKDHSFLTNDELAVLPVVKVLPSGKYTGANLKSVIRVLRGLLDQGIPSK 2215
Query: 2221 ELENLQELKPLDQCLIGQTKENRRKNRYKNILPYDATRVPLGDEGGYINASFIKIPVGKE 2280
ELENLQELKPLDQCLIGQTKENRRKNRYKNILPYDATRVPLGDEGGYINASFIKIPVGKE
Sbjct: 2216 ELENLQELKPLDQCLIGQTKENRRKNRYKNILPYDATRVPLGDEGGYINASFIKIPVGKE 2275
Query: 2281 EFVYIACQGPLPTTVGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSN 2340
EFVYIACQGPLPTTVGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSN
Sbjct: 2276 EFVYIACQGPLPTTVGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSN 2335
Query: 2341 RLRLALVRMQQLKGFVVRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYM 2400
RLRLALVRMQQLKGFVVRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYM
Sbjct: 2336 RLRLALVRMQQLKGFVVRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYM 2395
Query: 2401 RHIHRSGPIITHCSAGIGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTED 2460
RHIHRSGPIITHCSAGIGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTED
Sbjct: 2396 RHIHRSGPIITHCSAGIGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTED 2455
Query: 2461 QYIFCYQVILYVLTRLQAEEEQKQQPQLLK 2490
QYIFCYQVILYVLTRLQAEEEQKQQPQLLK
Sbjct: 2456 QYIFCYQVILYVLTRLQAEEEQKQQPQLLK 2485
>gi|5453992 protein tyrosine phosphatase, non-receptor type 13 isoform
2 [Homo sapiens]
Length = 2466
Score = 4886 bits (12673), Expect = 0.0
Identities = 2466/2490 (99%), Positives = 2466/2490 (99%), Gaps = 24/2490 (0%)
Query: 1 MHVSLAEALEVRGGPLQEEEIWAVLNQSAESLQELFRKVSLADPAALGFIISPWSLLLLP 60
MHVSLAEALEVRGGPLQEEEIWAVLNQSAESLQELFRKVSLADPAALGFIISPWSLLLLP
Sbjct: 1 MHVSLAEALEVRGGPLQEEEIWAVLNQSAESLQELFRKVSLADPAALGFIISPWSLLLLP 60
Query: 61 SGSVSFTDENISNQDLRAFTAPEVLQNQSLTSLSDVEKIHIYSLGMTLYWGADYEVPQSQ 120
SGSVSFTDENISNQDLRAFTAPEVLQNQSLTSLSDVEKIHIYSLGMTLYWGADYEVPQSQ
Sbjct: 61 SGSVSFTDENISNQDLRAFTAPEVLQNQSLTSLSDVEKIHIYSLGMTLYWGADYEVPQSQ 120
Query: 121 PIKLGDHLNSILLGMCEDVIYARVSVRTVLDACSAHIRNSNCAPSFSYVKHLVKLVLGNL 180
PIKLGDHLNSILLGMCEDVIYARVSVRTVLDACSAHIRNSNCAPSFSYVKHLVKLVLGNL
Sbjct: 121 PIKLGDHLNSILLGMCEDVIYARVSVRTVLDACSAHIRNSNCAPSFSYVKHLVKLVLGNL 180
Query: 181 SGTDQLSCNSEQKPDRSQAIRDRLRGKGLPTGRSSTSDVLDIQKPPLSHQTFLNKGLSKS 240
SGTDQLSCNSEQKPDRSQAIRDRLRGKGLPTGRSSTSDVLDIQKPPLSHQTFLNKGLSKS
Sbjct: 181 SGTDQLSCNSEQKPDRSQAIRDRLRGKGLPTGRSSTSDVLDIQKPPLSHQTFLNKGLSKS 240
Query: 241 MGFLSIKDTQDENYFKDILSDNSGREDSENTFSPYQFKTSGPEKKPIPGIDVLSKKKIWA 300
MGFLSIKDTQDENYFKDILSDNSGREDSENTFSPYQFKTSGPEKKPIPGIDVLSKKKIWA
Sbjct: 241 MGFLSIKDTQDENYFKDILSDNSGREDSENTFSPYQFKTSGPEKKPIPGIDVLSKKKIWA 300
Query: 301 SSMDLLCTADRDFSSGETATYRRCHPEAVTVRTSTTPRKKEARYSDGSIALDIFGPQKMD 360
SSMDLLCTADRDFSSGETATYRRCHPEAVTVRTSTTPRKKEARYSDGSIALDIFGPQKMD
Sbjct: 301 SSMDLLCTADRDFSSGETATYRRCHPEAVTVRTSTTPRKKEARYSDGSIALDIFGPQKMD 360
Query: 361 PIYHTRELPTSSAISSALDRIRERQKKLQVLREAMNVEEPVRRYKTYHGDVFSTSSESPS 420
PIYHTRELPTSSAISSALDRIRERQKKLQVLREAMNVEEPVRRYKTYHGDVFSTSSESPS
Sbjct: 361 PIYHTRELPTSSAISSALDRIRERQKKLQVLREAMNVEEPVRRYKTYHGDVFSTSSESPS 420
Query: 421 IISSESDFRQVRRSEASKRFESSSGLPGVDETLSQGQSQRPSRQYETPFEGNLINQEIML 480
IISSESDFRQVRRSEASKRFESSSGLPGVDETLSQGQSQRPSRQYETPFEGNLINQEIML
Sbjct: 421 IISSESDFRQVRRSEASKRFESSSGLPGVDETLSQGQSQRPSRQYETPFEGNLINQEIML 480
Query: 481 KRQEEELMQLQAKMALRQSRLSLYPGDTIKASMLDITRDPLREIALETAMTQRKLRNFFG 540
KRQEEELMQLQAKMALRQSRLSLYPGDTIKASMLDITRDPLREIALETAMTQRKLRNFFG
Sbjct: 481 KRQEEELMQLQAKMALRQSRLSLYPGDTIKASMLDITRDPLREIALETAMTQRKLRNFFG 540
Query: 541 PEFVKMTIEPFISLDLPRSILTKKGKNEDNRRKVNIMLLNGQRLELTCDTKTICKDVFDM 600
PEFVKMTIEPFISLDLPRSILTKKGKNEDNRRKVNIMLLNGQRLELTCDTKTICKDVFDM
Sbjct: 541 PEFVKMTIEPFISLDLPRSILTKKGKNEDNRRKVNIMLLNGQRLELTCDTKTICKDVFDM 600
Query: 601 VVAHIGLVEHHLFALATLKDNEYFFVDPDLKLTKVAPEGWKEEPKKKTKATVNFTLFFRI 660
VVAHIGLVEHHLFALATLKDNEYFFVDPDLKLTKVAPEGWKEEPKKKTKATVNFTLFFRI
Sbjct: 601 VVAHIGLVEHHLFALATLKDNEYFFVDPDLKLTKVAPEGWKEEPKKKTKATVNFTLFFRI 660
Query: 661 KFFMDDVSLIQHTLTCHQYYLQLRKDILEERMHCDDETSLLLASLALQAEYGDYQPEVHG 720
KFFMDDVSLIQHTLTCHQYYLQLRKDILEERMHCDDETSLLLASLALQAEYGDYQPEVHG
Sbjct: 661 KFFMDDVSLIQHTLTCHQYYLQLRKDILEERMHCDDETSLLLASLALQAEYGDYQPEVHG 720
Query: 721 VSYFRMEHYLPARVMEKLDLSYIKEELPKLHNTYVGASEKETELEFLKVCQRLTEYGVHF 780
VSYFRMEHYLPARVMEKLDLSYIKEELPKLHNTYVGASEKETELEFLKVCQRLTEYGVHF
Sbjct: 721 VSYFRMEHYLPARVMEKLDLSYIKEELPKLHNTYVGASEKETELEFLKVCQRLTEYGVHF 780
Query: 781 HRVHPEKKSQTGILLGVCSKGVLVFEVHNGVRTLVLRFPWRETKKISFSKKKITLQNTSD 840
HRVHPEKKSQTGILLGVCSKGVLVFEVHNGVRTLVLRFPWRETKKISFSKKKITLQNTSD
Sbjct: 781 HRVHPEKKSQTGILLGVCSKGVLVFEVHNGVRTLVLRFPWRETKKISFSKKKITLQNTSD 840
Query: 841 GIKHGFQTDNSKICQYLLHLCSYQHKFQLQMRARQSNQDAQDIERASFRSLNLQAESVRG 900
GIKHGFQTDNSKICQYLLHLCSYQHKFQLQMRARQSNQDAQDIERASFRSLNLQAESVRG
Sbjct: 841 GIKHGFQTDNSKICQYLLHLCSYQHKFQLQMRARQSNQDAQDIERASFRSLNLQAESVRG 900
Query: 901 FNMGRAISTGSLASSTLNKLAVRPLSVQAEILKRLSCSELSLYQPLQNSSKEKNDKASWE 960
FNMGRAISTGSLASSTLNKLAVRPLSVQAEILKRLSCSELSLYQPLQNSSKEKNDKASWE
Sbjct: 901 FNMGRAISTGSLASSTLNKLAVRPLSVQAEILKRLSCSELSLYQPLQNSSKEKNDKASWE 960
Query: 961 EKPREMSKSYHDLSQASLYPHRKNVIVNMEPPPQTVAELVGKPSHQMSRSDAESLAGVTK 1020
EKPREMSKSYHDLSQASLYPHRKNVIVNMEPPPQTVAELVGKPSHQMSRSDAESLAGVTK
Sbjct: 961 EKPREMSKSYHDLSQASLYPHRKNVIVNMEPPPQTVAELVGKPSHQMSRSDAESLAGVTK 1020
Query: 1021 LNNSKSVASLNRSPERRKHESDSSSIEDPGQAYVLGMTMHSSGNSSSQVPLKENDVLHKR 1080
LNNSKSVASLNRSPERRKHESDSSSIEDPGQAYVL DVLHKR
Sbjct: 1021 LNNSKSVASLNRSPERRKHESDSSSIEDPGQAYVL-------------------DVLHKR 1061
Query: 1081 WSIVSSPEREITLVNLKKDAKYGLGFQIIGGEKMGRLDLGIFISSVAPGGPADLDGCLKP 1140
WSIVSSPEREITLVNLKKDAKYGLGFQIIGGEKMGRLDLGIFISSVAPGGPADLDGCLKP
Sbjct: 1062 WSIVSSPEREITLVNLKKDAKYGLGFQIIGGEKMGRLDLGIFISSVAPGGPADLDGCLKP 1121
Query: 1141 GDRLISVNSVSLEGVSHHAAIEILQNAPEDVTLVISQPKEKISKVPSTPVHLTNEMKNYM 1200
GDRLISVNSVSLEGVSHHAAIEILQNAPEDVTLVISQPKEKISKVPSTPVHLTNEMKNYM
Sbjct: 1122 GDRLISVNSVSLEGVSHHAAIEILQNAPEDVTLVISQPKEKISKVPSTPVHLTNEMKNYM 1181
Query: 1201 KKSSYMQDSAIDSSSKDHHWSRGTLRHISENSFGPSGGLREGSLSSQDSRTESASLSQSQ 1260
KKSSYMQDSAIDSSSKDHHWSRGTLRHISENSFGPSGGLREGSLSSQDSRTESASLSQSQ
Sbjct: 1182 KKSSYMQDSAIDSSSKDHHWSRGTLRHISENSFGPSGGLREGSLSSQDSRTESASLSQSQ 1241
Query: 1261 VNGFFASHLGDQTWQESQHGSPSPSVISKATEKETFTDSNQSKTKKPGISDVTDYSDRGD 1320
VNGFFASHLGDQTWQESQHGSPSPSVISKATEKETFTDSNQSKTKKPGISDVTDYSDRGD
Sbjct: 1242 VNGFFASHLGDQTWQESQHGSPSPSVISKATEKETFTDSNQSKTKKPGISDVTDYSDRGD 1301
Query: 1321 SDMDEATYSSSQDHQTPKQESSSSVNTSNKMNFKTFSSSPPKPGDIFEVELAKNDNSLGI 1380
SDMDEATYSSSQDHQTPKQESSSSVNTSNKMNFKTFSSSPPKPGDIFEVELAKNDNSLGI
Sbjct: 1302 SDMDEATYSSSQDHQTPKQESSSSVNTSNKMNFKTFSSSPPKPGDIFEVELAKNDNSLGI 1361
Query: 1381 SVTVLFDKGGVNTSVRHGGIYVKAVIPQGAAESDGRIHKGDRVLAVNGVSLEGATHKQAV 1440
SVT GGVNTSVRHGGIYVKAVIPQGAAESDGRIHKGDRVLAVNGVSLEGATHKQAV
Sbjct: 1362 SVT-----GGVNTSVRHGGIYVKAVIPQGAAESDGRIHKGDRVLAVNGVSLEGATHKQAV 1416
Query: 1441 ETLRNTGQVVHLLLEKGQSPTSKEHVPVTPQCTLSDQNAQGQGPEKVKKTTQVKDYSFVT 1500
ETLRNTGQVVHLLLEKGQSPTSKEHVPVTPQCTLSDQNAQGQGPEKVKKTTQVKDYSFVT
Sbjct: 1417 ETLRNTGQVVHLLLEKGQSPTSKEHVPVTPQCTLSDQNAQGQGPEKVKKTTQVKDYSFVT 1476
Query: 1501 EENTFEVKLFKNSSGLGFSFSREDNLIPEQINASIVRVKKLFPGQPAAESGKIDVGDVIL 1560
EENTFEVKLFKNSSGLGFSFSREDNLIPEQINASIVRVKKLFPGQPAAESGKIDVGDVIL
Sbjct: 1477 EENTFEVKLFKNSSGLGFSFSREDNLIPEQINASIVRVKKLFPGQPAAESGKIDVGDVIL 1536
Query: 1561 KVNGASLKGLSQQEVISALRGTAPEVFLLLCRPPPGVLPEIDTALLTPLQSPAQVLPNSS 1620
KVNGASLKGLSQQEVISALRGTAPEVFLLLCRPPPGVLPEIDTALLTPLQSPAQVLPNSS
Sbjct: 1537 KVNGASLKGLSQQEVISALRGTAPEVFLLLCRPPPGVLPEIDTALLTPLQSPAQVLPNSS 1596
Query: 1621 KDSSQPSCVEQSTSSDENEMSDKSKKQCKSPSRRDSYSDSSGSGEDDLVTAPANISNSTW 1680
KDSSQPSCVEQSTSSDENEMSDKSKKQCKSPSRRDSYSDSSGSGEDDLVTAPANISNSTW
Sbjct: 1597 KDSSQPSCVEQSTSSDENEMSDKSKKQCKSPSRRDSYSDSSGSGEDDLVTAPANISNSTW 1656
Query: 1681 SSALHQTLSNMVSQAQSHHEAPKSQEDTICTMFYYPQKIPNKPEFEDSNPSPLPPDMAPG 1740
SSALHQTLSNMVSQAQSHHEAPKSQEDTICTMFYYPQKIPNKPEFEDSNPSPLPPDMAPG
Sbjct: 1657 SSALHQTLSNMVSQAQSHHEAPKSQEDTICTMFYYPQKIPNKPEFEDSNPSPLPPDMAPG 1716
Query: 1741 QSYQPQSESASSSSMDKYHIHHISEPTRQENWTPLKNDLENHLEDFELEVELLITLIKSE 1800
QSYQPQSESASSSSMDKYHIHHISEPTRQENWTPLKNDLENHLEDFELEVELLITLIKSE
Sbjct: 1717 QSYQPQSESASSSSMDKYHIHHISEPTRQENWTPLKNDLENHLEDFELEVELLITLIKSE 1776
Query: 1801 KGSLGFTVTKGNQRIGCYVHDVIQDPAKSDGRLKPGDRLIKVNDTDVTNMTHTDAVNLLR 1860
KGSLGFTVTKGNQRIGCYVHDVIQDPAKSDGRLKPGDRLIKVNDTDVTNMTHTDAVNLLR
Sbjct: 1777 KGSLGFTVTKGNQRIGCYVHDVIQDPAKSDGRLKPGDRLIKVNDTDVTNMTHTDAVNLLR 1836
Query: 1861 AASKTVRLVIGRVLELPRIPMLPHLLPDITLTCNKEELGFSLCGGHDSLYQVVYISDINP 1920
AASKTVRLVIGRVLELPRIPMLPHLLPDITLTCNKEELGFSLCGGHDSLYQVVYISDINP
Sbjct: 1837 AASKTVRLVIGRVLELPRIPMLPHLLPDITLTCNKEELGFSLCGGHDSLYQVVYISDINP 1896
Query: 1921 RSVAAIEGNLQLLDVIHYVNGVSTQGMTLEEVNRALDMSLPSLVLKATRNDLPVVPSSKR 1980
RSVAAIEGNLQLLDVIHYVNGVSTQGMTLEEVNRALDMSLPSLVLKATRNDLPVVPSSKR
Sbjct: 1897 RSVAAIEGNLQLLDVIHYVNGVSTQGMTLEEVNRALDMSLPSLVLKATRNDLPVVPSSKR 1956
Query: 1981 SAVSAPKSTKGNGSYSVGSCSQPALTPNDSFSTVAGEEINEISYPKGKCSTYQIKGSPNL 2040
SAVSAPKSTKGNGSYSVGSCSQPALTPNDSFSTVAGEEINEISYPKGKCSTYQIKGSPNL
Sbjct: 1957 SAVSAPKSTKGNGSYSVGSCSQPALTPNDSFSTVAGEEINEISYPKGKCSTYQIKGSPNL 2016
Query: 2041 TLPKESYIQEDDIYDDSQEAEVIQSLLDVVDEEAQNLLNENNAAGYSCGPGTLKMNGKLS 2100
TLPKESYIQEDDIYDDSQEAEVIQSLLDVVDEEAQNLLNENNAAGYSCGPGTLKMNGKLS
Sbjct: 2017 TLPKESYIQEDDIYDDSQEAEVIQSLLDVVDEEAQNLLNENNAAGYSCGPGTLKMNGKLS 2076
Query: 2101 EERTEDTDCDGSPLPEYFTEATKMNGCEEYCEEKVKSESLIQKPQEKKTDDDEITWGNDE 2160
EERTEDTDCDGSPLPEYFTEATKMNGCEEYCEEKVKSESLIQKPQEKKTDDDEITWGNDE
Sbjct: 2077 EERTEDTDCDGSPLPEYFTEATKMNGCEEYCEEKVKSESLIQKPQEKKTDDDEITWGNDE 2136
Query: 2161 LPIERTNHEDSDKDHSFLTNDELAVLPVVKVLPSGKYTGANLKSVIRVLRGLLDQGIPSK 2220
LPIERTNHEDSDKDHSFLTNDELAVLPVVKVLPSGKYTGANLKSVIRVLRGLLDQGIPSK
Sbjct: 2137 LPIERTNHEDSDKDHSFLTNDELAVLPVVKVLPSGKYTGANLKSVIRVLRGLLDQGIPSK 2196
Query: 2221 ELENLQELKPLDQCLIGQTKENRRKNRYKNILPYDATRVPLGDEGGYINASFIKIPVGKE 2280
ELENLQELKPLDQCLIGQTKENRRKNRYKNILPYDATRVPLGDEGGYINASFIKIPVGKE
Sbjct: 2197 ELENLQELKPLDQCLIGQTKENRRKNRYKNILPYDATRVPLGDEGGYINASFIKIPVGKE 2256
Query: 2281 EFVYIACQGPLPTTVGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSN 2340
EFVYIACQGPLPTTVGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSN
Sbjct: 2257 EFVYIACQGPLPTTVGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSN 2316
Query: 2341 RLRLALVRMQQLKGFVVRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYM 2400
RLRLALVRMQQLKGFVVRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYM
Sbjct: 2317 RLRLALVRMQQLKGFVVRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYM 2376
Query: 2401 RHIHRSGPIITHCSAGIGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTED 2460
RHIHRSGPIITHCSAGIGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTED
Sbjct: 2377 RHIHRSGPIITHCSAGIGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTED 2436
Query: 2461 QYIFCYQVILYVLTRLQAEEEQKQQPQLLK 2490
QYIFCYQVILYVLTRLQAEEEQKQQPQLLK
Sbjct: 2437 QYIFCYQVILYVLTRLQAEEEQKQQPQLLK 2466
>gi|18375648 protein tyrosine phosphatase, non-receptor type 13
isoform 3 [Homo sapiens]
Length = 2294
Score = 2814 bits (7294), Expect = 0.0
Identities = 1423/1480 (96%), Positives = 1434/1480 (96%), Gaps = 19/1480 (1%)
Query: 1020 KLNNSKSVASLNRSPERRKH--ESDSSSIEDP-------GQAYVLGMTMHSSGNSSSQVP 1070
K++ SK +L + + KH ++D+S I + L M S + +
Sbjct: 825 KISFSKKKITLQNTSDGIKHGFQTDNSKICQYLLHLCSYQHKFQLQMRARQSNQDAQDI- 883
Query: 1071 LKENDVLHKRWSIVSSPEREITLVNLKKDAKYGLGFQIIGGEKMGRLDLGIFISSVAPGG 1130
DVLHKRWSIVSSPEREITLVNLKKDAKYGLGFQIIGGEKMGRLDLGIFISSVAPGG
Sbjct: 884 ----DVLHKRWSIVSSPEREITLVNLKKDAKYGLGFQIIGGEKMGRLDLGIFISSVAPGG 939
Query: 1131 PADLDGCLKPGDRLISVNSVSLEGVSHHAAIEILQNAPEDVTLVISQPKEKISKVPSTPV 1190
PADLDGCLKPGDRLISVNSVSLEGVSHHAAIEILQNAPEDVTLVISQPKEKISKVPSTPV
Sbjct: 940 PADLDGCLKPGDRLISVNSVSLEGVSHHAAIEILQNAPEDVTLVISQPKEKISKVPSTPV 999
Query: 1191 HLTNEMKNYMKKSSYMQDSAIDSSSKDHHWSRGTLRHISENSFGPSGGLREGSLSSQDSR 1250
HLTNEMKNYMKKSSYMQDSAIDSSSKDHHWSRGTLRHISENSFGPSGGLREGSLSSQDSR
Sbjct: 1000 HLTNEMKNYMKKSSYMQDSAIDSSSKDHHWSRGTLRHISENSFGPSGGLREGSLSSQDSR 1059
Query: 1251 TESASLSQSQVNGFFASHLGDQTWQESQHGSPSPSVISKATEKETFTDSNQSKTKKPGIS 1310
TESASLSQSQVNGFFASHLGDQTWQESQHGSPSPSVISKATEKETFTDSNQSKTKKPGIS
Sbjct: 1060 TESASLSQSQVNGFFASHLGDQTWQESQHGSPSPSVISKATEKETFTDSNQSKTKKPGIS 1119
Query: 1311 DVTDYSDRGDSDMDEATYSSSQDHQTPKQESSSSVNTSNKMNFKTFSSSPPKPGDIFEVE 1370
DVTDYSDRGDSDMDEATYSSSQDHQTPKQESSSSVNTSNKMNFKTFSSSPPKPGDIFEVE
Sbjct: 1120 DVTDYSDRGDSDMDEATYSSSQDHQTPKQESSSSVNTSNKMNFKTFSSSPPKPGDIFEVE 1179
Query: 1371 LAKNDNSLGISVTVLFDKGGVNTSVRHGGIYVKAVIPQGAAESDGRIHKGDRVLAVNGVS 1430
LAKNDNSLGISVT GGVNTSVRHGGIYVKAVIPQGAAESDGRIHKGDRVLAVNGVS
Sbjct: 1180 LAKNDNSLGISVT-----GGVNTSVRHGGIYVKAVIPQGAAESDGRIHKGDRVLAVNGVS 1234
Query: 1431 LEGATHKQAVETLRNTGQVVHLLLEKGQSPTSKEHVPVTPQCTLSDQNAQGQGPEKVKKT 1490
LEGATHKQAVETLRNTGQVVHLLLEKGQSPTSKEHVPVTPQCTLSDQNAQGQGPEKVKKT
Sbjct: 1235 LEGATHKQAVETLRNTGQVVHLLLEKGQSPTSKEHVPVTPQCTLSDQNAQGQGPEKVKKT 1294
Query: 1491 TQVKDYSFVTEENTFEVKLFKNSSGLGFSFSREDNLIPEQINASIVRVKKLFPGQPAAES 1550
TQVKDYSFVTEENTFEVKLFKNSSGLGFSFSREDNLIPEQINASIVRVKKLFPGQPAAES
Sbjct: 1295 TQVKDYSFVTEENTFEVKLFKNSSGLGFSFSREDNLIPEQINASIVRVKKLFPGQPAAES 1354
Query: 1551 GKIDVGDVILKVNGASLKGLSQQEVISALRGTAPEVFLLLCRPPPGVLPEIDTALLTPLQ 1610
GKIDVGDVILKVNGASLKGLSQQEVISALRGTAPEVFLLLCRPPPGVLPEIDTALLTPLQ
Sbjct: 1355 GKIDVGDVILKVNGASLKGLSQQEVISALRGTAPEVFLLLCRPPPGVLPEIDTALLTPLQ 1414
Query: 1611 SPAQVLPNSSKDSSQPSCVEQSTSSDENEMSDKSKKQCKSPSRRDSYSDSSGSGEDDLVT 1670
SPAQVLPNSSKDSSQPSCVEQSTSSDENEMSDKSKKQCKSPSRRDSYSDSSGSGEDDLVT
Sbjct: 1415 SPAQVLPNSSKDSSQPSCVEQSTSSDENEMSDKSKKQCKSPSRRDSYSDSSGSGEDDLVT 1474
Query: 1671 APANISNSTWSSALHQTLSNMVSQAQSHHEAPKSQEDTICTMFYYPQKIPNKPEFEDSNP 1730
APANISNSTWSSALHQTLSNMVSQAQSHHEAPKSQEDTICTMFYYPQKIPNKPEFEDSNP
Sbjct: 1475 APANISNSTWSSALHQTLSNMVSQAQSHHEAPKSQEDTICTMFYYPQKIPNKPEFEDSNP 1534
Query: 1731 SPLPPDMAPGQSYQPQSESASSSSMDKYHIHHISEPTRQENWTPLKNDLENHLEDFELEV 1790
SPLPPDMAPGQSYQPQSESASSSSMDKYHIHHISEPTRQENWTPLKNDLENHLEDFELEV
Sbjct: 1535 SPLPPDMAPGQSYQPQSESASSSSMDKYHIHHISEPTRQENWTPLKNDLENHLEDFELEV 1594
Query: 1791 ELLITLIKSEKGSLGFTVTKGNQRIGCYVHDVIQDPAKSDGRLKPGDRLIKVNDTDVTNM 1850
ELLITLIKSEKGSLGFTVTKGNQRIGCYVHDVIQDPAKSDGRLKPGDRLIKVNDTDVTNM
Sbjct: 1595 ELLITLIKSEKGSLGFTVTKGNQRIGCYVHDVIQDPAKSDGRLKPGDRLIKVNDTDVTNM 1654
Query: 1851 THTDAVNLLRAASKTVRLVIGRVLELPRIPMLPHLLPDITLTCNKEELGFSLCGGHDSLY 1910
THTDAVNLLRAASKTVRLVIGRVLELPRIPMLPHLLPDITLTCNKEELGFSLCGGHDSLY
Sbjct: 1655 THTDAVNLLRAASKTVRLVIGRVLELPRIPMLPHLLPDITLTCNKEELGFSLCGGHDSLY 1714
Query: 1911 QVVYISDINPRSVAAIEGNLQLLDVIHYVNGVSTQGMTLEEVNRALDMSLPSLVLKATRN 1970
QVVYISDINPRSVAAIEGNLQLLDVIHYVNGVSTQGMTLEEVNRALDMSLPSLVLKATRN
Sbjct: 1715 QVVYISDINPRSVAAIEGNLQLLDVIHYVNGVSTQGMTLEEVNRALDMSLPSLVLKATRN 1774
Query: 1971 DLPVVPSSKRSAVSAPKSTKGNGSYSVGSCSQPALTPNDSFSTVAGEEINEISYPKGKCS 2030
DLPVVPSSKRSAVSAPKSTKGNGSYSVGSCSQPALTPNDSFSTVAGEEINEISYPKGKCS
Sbjct: 1775 DLPVVPSSKRSAVSAPKSTKGNGSYSVGSCSQPALTPNDSFSTVAGEEINEISYPKGKCS 1834
Query: 2031 TYQIKGSPNLTLPKESYIQEDDIYDDSQEAEVIQSLLDVVDEEAQNLLNENNAAGYSCGP 2090
TYQIKGSPNLTLPKESYIQEDDIYDDSQEAEVIQSLLDVVDEEAQNLLNENNAAGYSCGP
Sbjct: 1835 TYQIKGSPNLTLPKESYIQEDDIYDDSQEAEVIQSLLDVVDEEAQNLLNENNAAGYSCGP 1894
Query: 2091 GTLKMNGKLSEERTEDTDCDGSPLPEYFTEATKMNGCEEYCEEKVKSESLIQKPQEKKTD 2150
GTLKMNGKLSEERTEDTDCDGSPLPEYFTEATKMNGCEEYCEEKVKSESLIQKPQEKKTD
Sbjct: 1895 GTLKMNGKLSEERTEDTDCDGSPLPEYFTEATKMNGCEEYCEEKVKSESLIQKPQEKKTD 1954
Query: 2151 DDEITWGNDELPIERTNHEDSDKDHSFLTNDELAVLPVVKVLPSGKYTGANLKSVIRVLR 2210
DDEITWGNDELPIERTNHEDSDKDHSFLTNDELAVLPVVKVLPSGKYTGANLKSVIRVLR
Sbjct: 1955 DDEITWGNDELPIERTNHEDSDKDHSFLTNDELAVLPVVKVLPSGKYTGANLKSVIRVLR 2014
Query: 2211 GLLDQGIPSKELENLQELKPLDQCLIGQTKENRRKNRYKNILPYDATRVPLGDEGGYINA 2270
GLLDQGIPSKELENLQELKPLDQCLIGQTKENRRKNRYKNILPYDATRVPLGDEGGYINA
Sbjct: 2015 GLLDQGIPSKELENLQELKPLDQCLIGQTKENRRKNRYKNILPYDATRVPLGDEGGYINA 2074
Query: 2271 SFIKIPVGKEEFVYIACQGPLPTTVGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPN 2330
SFIKIPVGKEEFVYIACQGPLPTTVGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPN
Sbjct: 2075 SFIKIPVGKEEFVYIACQGPLPTTVGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPN 2134
Query: 2331 ILGKTTMVSNRLRLALVRMQQLKGFVVRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQP 2390
ILGKTTMVSNRLRLALVRMQQLKGFVVRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQP
Sbjct: 2135 ILGKTTMVSNRLRLALVRMQQLKGFVVRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQP 2194
Query: 2391 DDLLTFISYMRHIHRSGPIITHCSAGIGRSGTLICIDVVLGLISQDLDFDISDLVRCMRL 2450
DDLLTFISYMRHIHRSGPIITHCSAGIGRSGTLICIDVVLGLISQDLDFDISDLVRCMRL
Sbjct: 2195 DDLLTFISYMRHIHRSGPIITHCSAGIGRSGTLICIDVVLGLISQDLDFDISDLVRCMRL 2254
Query: 2451 QRHGMVQTEDQYIFCYQVILYVLTRLQAEEEQKQQPQLLK 2490
QRHGMVQTEDQYIFCYQVILYVLTRLQAEEEQKQQPQLLK
Sbjct: 2255 QRHGMVQTEDQYIFCYQVILYVLTRLQAEEEQKQQPQLLK 2294
Score = 1805 bits (4675), Expect = 0.0
Identities = 974/1280 (76%), Positives = 1035/1280 (80%), Gaps = 97/1280 (7%)
Query: 1 MHVSLAEALEVRGGPLQEEEIWAVLNQSAESLQELFRKVSLADPAALGFIISPWSLLLLP 60
MHVSLAEALEVRGGPLQEEEIWAVLNQSAESLQELFRKVSLADPAALGFIISPWSLLLLP
Sbjct: 1 MHVSLAEALEVRGGPLQEEEIWAVLNQSAESLQELFRKVSLADPAALGFIISPWSLLLLP 60
Query: 61 SGSVSFTDENISNQDLRAFTAPEVLQNQSLTSLSDVEKIHIYSLGMTLYWGADYEVPQSQ 120
SGSVSFTDENISNQDLRAFTAPEVLQNQSLTSLSDVEKIHIYSLGMTLYWGADYEVPQSQ
Sbjct: 61 SGSVSFTDENISNQDLRAFTAPEVLQNQSLTSLSDVEKIHIYSLGMTLYWGADYEVPQSQ 120
Query: 121 PIKLGDHLNSILLGMCEDVIYARVSVRTVLDACSAHIRNSNCAPSFSYVKHLVKLVLGNL 180
PIKLGDHLNSILLGMCEDVIYARVSVRTVLDACSAHIRNSNCAPSFSYVKHLVKLVLGNL
Sbjct: 121 PIKLGDHLNSILLGMCEDVIYARVSVRTVLDACSAHIRNSNCAPSFSYVKHLVKLVLGNL 180
Query: 181 SGTDQLSCNSEQKPDRSQAIRDRLRGKGLPTGRSSTSDVLDIQKPPLSHQTFLNKGLSKS 240
SGTDQLSCNSEQKPDRSQAIRDRLRGKGLPTGRSSTSDVLDIQKPPLSHQTFLNKGLSKS
Sbjct: 181 SGTDQLSCNSEQKPDRSQAIRDRLRGKGLPTGRSSTSDVLDIQKPPLSHQTFLNKGLSKS 240
Query: 241 MGFLSIKDTQDENYFKDILSDNSGREDSENTFSPYQFKTSGPEKKPIPGIDVLSKKKIWA 300
MGFLSIKDTQDENYFKDILSDNSGREDSENTFSPYQFKTSGPEKKPIPGIDVLSKKKIWA
Sbjct: 241 MGFLSIKDTQDENYFKDILSDNSGREDSENTFSPYQFKTSGPEKKPIPGIDVLSKKKIWA 300
Query: 301 SSMDLLCTADRDFSSGETATYRRCHPEAVTVRTSTTPRKKEARYSDGSIALDIFGPQKMD 360
SSMDLLCTADRDFSSGETATYRRCHPEAVTVRTSTTPRKKEARYSDGSIALDIFGPQKMD
Sbjct: 301 SSMDLLCTADRDFSSGETATYRRCHPEAVTVRTSTTPRKKEARYSDGSIALDIFGPQKMD 360
Query: 361 PIYHTRELPTSSAISSALDRIRERQKKLQVLREAMNVEEPVRRYKTYHGDVFSTSSESPS 420
PIYHTRELPTSSAISSALDRIRERQKKLQVLREAMNVEEPVRRYKTYHGDVFSTSSESPS
Sbjct: 361 PIYHTRELPTSSAISSALDRIRERQKKLQVLREAMNVEEPVRRYKTYHGDVFSTSSESPS 420
Query: 421 IISSESDFRQVRRSEASKRFESSSGLPGVDETLSQGQSQRPSRQYETPFEGNLINQEIML 480
IISSESDFRQVRRSEASKRFESSSGLPGVDETLSQGQSQRPSRQYETPFEGNLINQEIML
Sbjct: 421 IISSESDFRQVRRSEASKRFESSSGLPGVDETLSQGQSQRPSRQYETPFEGNLINQEIML 480
Query: 481 KRQEEELMQLQAKMALRQSRLSLYPGDTIKASMLDITRDPLREIALETAMTQRKLRNFFG 540
KRQEEELMQLQAKMALRQSRLSLYPGDTIKASMLDITRDPLREIALETAMTQRKLRNFFG
Sbjct: 481 KRQEEELMQLQAKMALRQSRLSLYPGDTIKASMLDITRDPLREIALETAMTQRKLRNFFG 540
Query: 541 PEFVKMTIEPFISLDLPRSILTKKGKNEDNRRKVNIMLLNGQRLELTCDTKTICKDVFDM 600
PEFVKMTIEPFISLDLPRSILTKKGKNEDNRRKVNIMLLNGQRLELTCDTKTICKDVFDM
Sbjct: 541 PEFVKMTIEPFISLDLPRSILTKKGKNEDNRRKVNIMLLNGQRLELTCDTKTICKDVFDM 600
Query: 601 VVAHIGLVEHHLFALATLKDNEYFFVDPDLKLTKVAPEGWKEEPKKKTKATVNFTLFFRI 660
VVAHIGLVEHHLFALATLKDNEYFFVDPDLKLTKVAPEGWKEEPKKKTKATVNFTLFFRI
Sbjct: 601 VVAHIGLVEHHLFALATLKDNEYFFVDPDLKLTKVAPEGWKEEPKKKTKATVNFTLFFRI 660
Query: 661 KFFMDDVSLIQHTLTCHQYYLQLRKDILEERMHCDDETSLLLASLALQAEYGDYQPEVHG 720
KFFMDDVSLIQHTLTCHQYYLQLRKDILEERMHCDDETSLLLASLALQAEYGDYQPEVHG
Sbjct: 661 KFFMDDVSLIQHTLTCHQYYLQLRKDILEERMHCDDETSLLLASLALQAEYGDYQPEVHG 720
Query: 721 VSYFRMEHYLPARVMEKLDLSYIKEELPKLHNTYVGASEKETELEFLKVCQRLTEYGVHF 780
VSYFRMEHYLPARVMEKLDLSYIKEELPKLHNTYVGASEKETELEFLKVCQRLTEYGVHF
Sbjct: 721 VSYFRMEHYLPARVMEKLDLSYIKEELPKLHNTYVGASEKETELEFLKVCQRLTEYGVHF 780
Query: 781 HRVHPEKKSQTGILLGVCSKGVLVFEVHNGVRTLVLRFPWRETKKISFSKKKITLQNTSD 840
HRVHPEKKSQTGILLGVCSKGVLVFEVHNGVRTLVLRFPWRETKKISFSKKKITLQNTSD
Sbjct: 781 HRVHPEKKSQTGILLGVCSKGVLVFEVHNGVRTLVLRFPWRETKKISFSKKKITLQNTSD 840
Query: 841 GIKHGFQTDNSKICQYLLHLCSYQHKFQLQMRARQSNQDAQDIE------------RASF 888
GIKHGFQTDNSKICQYLLHLCSYQHKFQLQMRARQSNQDAQDI+
Sbjct: 841 GIKHGFQTDNSKICQYLLHLCSYQHKFQLQMRARQSNQDAQDIDVLHKRWSIVSSPEREI 900
Query: 889 RSLNLQAES--------VRGFNMGRAISTGSLASS--------------------TLNKL 920
+NL+ ++ + G MGR + G SS ++N +
Sbjct: 901 TLVNLKKDAKYGLGFQIIGGEKMGR-LDLGIFISSVAPGGPADLDGCLKPGDRLISVNSV 959
Query: 921 AVRPLSVQAEILKRLSCSE---LSLYQPLQNSSKE-------KNDKASWEEKPREMSKSY 970
++ +S A I + E L + QP + SK N+ ++ +K M S
Sbjct: 960 SLEGVSHHAAIEILQNAPEDVTLVISQPKEKISKVPSTPVHLTNEMKNYMKKSSYMQDSA 1019
Query: 971 HDLSQASLYPHR---KNVIVNMEPPPQTVAELVGKPSHQMSRSDAESLAG---------- 1017
D S + R +++ N P + E G S Q SR+++ SL+
Sbjct: 1020 IDSSSKDHHWSRGTLRHISENSFGPSGGLRE--GSLSSQDSRTESASLSQSQVNGFFASH 1077
Query: 1018 ------------------VTKLNNSKSVASLNRSPERRKHESDSSSIEDPGQAYVLGMTM 1059
++K ++ N+S ++ SD + D G + + T
Sbjct: 1078 LGDQTWQESQHGSPSPSVISKATEKETFTDSNQSKTKKPGISDVTDYSDRGDSDMDEATY 1137
Query: 1060 HSSGNSSSQVPLKE--------NDVLHKRWSIVSSPEREITLVNLKKDAKYGLGFQIIGG 1111
SS Q P +E N + K +S +I V L K+ LG + GG
Sbjct: 1138 SSS--QDHQTPKQESSSSVNTSNKMNFKTFSSSPPKPGDIFEVELAKNDN-SLGISVTGG 1194
Query: 1112 EKMGRLDLGIFISSVAPGGPADLDGCLKPGDRLISVNSVSLEGVSHHAAIEILQNAPEDV 1171
GI++ +V P G A+ DG + GDR+++VN VSLEG +H A+E L+N + V
Sbjct: 1195 VNTSVRHGGIYVKAVIPQGAAESDGRIHKGDRVLAVNGVSLEGATHKQAVETLRNTGQVV 1254
Query: 1172 TLVISQPKEKISK--VPSTP 1189
L++ + + SK VP TP
Sbjct: 1255 HLLLEKGQSPTSKEHVPVTP 1274
>gi|110346438 FERM and PDZ domain containing 2 isoform 1 [Homo
sapiens]
Length = 1287
Score = 297 bits (761), Expect = 8e-80
Identities = 157/340 (46%), Positives = 225/340 (66%), Gaps = 4/340 (1%)
Query: 538 FFGPEFVKMTIEPFISLDLPRSILTKKGKNEDNRRKVNIMLLNGQRLELTCDTKTICKDV 597
F PEF+ + E ++L LP S++TKKGK+ R + ++LLNGQ LE+ CD ++ V
Sbjct: 286 FSRPEFILLAGEAPMTLHLPGSVVTKKGKSYLALRDLCVVLLNGQHLEVKCDVESTVGAV 345
Query: 598 FDMVVAHIGLVEHHLFALATLKDNEYFFVDPDLKLTKVAPEGWKEEPKKKTKATVNFTLF 657
F+ V + L E F LA +K E+FF+D + +L K+APEGW+E+P+K + T FTLF
Sbjct: 346 FNAVTSFANLEELTYFGLAYMKSKEFFFLDSETRLCKIAPEGWREQPQKTSMNT--FTLF 403
Query: 658 FRIKFFMDDVSLIQHTLTCHQYYLQLRKDILEERMHCDDETSLLLASLALQAEYGDYQPE 717
RIKFF+ L+QH+LT HQ+YLQLRKDILEER++C++E L L LALQAE+G+Y E
Sbjct: 404 LRIKFFVSHYGLLQHSLTRHQFYLQLRKDILEERLYCNEEILLQLGVLALQAEFGNYPKE 463
Query: 718 -VHGVSYFRMEHYLPARVMEKLDLSYIKEELPKLHNTYVGASEKETELEFLKVCQRLTEY 776
V YF +E Y+PA ++E++ ++ E+ ++H ++ EL+FL+V Q+L EY
Sbjct: 464 QVESKPYFHVEDYIPASLIERMTALRVQVEVSEMHRLSSALWGEDAELKFLRVTQQLPEY 523
Query: 777 GVHFHRVHPEK-KSQTGILLGVCSKGVLVFEVHNGVRTLVLRFPWRETKKISFSKKKITL 835
GV H+V EK + + + LG+C+KGV+V+EV N R +LRF WRET KIS +KK T+
Sbjct: 524 GVLVHQVFSEKRRPEEEMALGICAKGVIVYEVKNNSRIAMLRFQWRETGKISTYQKKFTI 583
Query: 836 QNTSDGIKHGFQTDNSKICQYLLHLCSYQHKFQLQMRARQ 875
++ G KH F TD++K +YLL LCS QH F QM + Q
Sbjct: 584 TSSVTGKKHTFVTDSAKTSKYLLDLCSAQHGFNAQMGSGQ 623
Score = 214 bits (545), Expect = 8e-55
Identities = 144/386 (37%), Positives = 205/386 (53%), Gaps = 53/386 (13%)
Query: 1298 DSNQSKTKKPGIS--DVTDYSDRGDSDMDEATYSSSQDHQTPKQESSSSVNTSNKMNFKT 1355
D ++ T G+S D+ + +G +++ QD T + + + + ++ +
Sbjct: 847 DEEKNSTANSGVSSTDILSFGYQGSL----LSHTQDQDRNTEELDMAGVQSLVPRLRHQL 902
Query: 1356 F--------SSSPPKP-----GDIFEVELAKNDNSLGISVTVLFDKGGVNTSVRHGGIYV 1402
SS PP P G+I+ VEL K D +LG SVT GG+NTSV +GGIYV
Sbjct: 903 SFLPLKGAGSSCPPSPPEISAGEIYFVELVKEDGTLGFSVT-----GGINTSVPYGGIYV 957
Query: 1403 KAVIPQGAAESDGRIHKGDRVLAVNGVSLEGATHKQAVETLRNTGQVVHLLLEKGQSPTS 1462
K+++P G A +G+I +GDR+L V+GV L G THKQAV+ L GQV L+LE+
Sbjct: 958 KSIVPGGPAAKEGQILQGDRLLQVDGVILCGLTHKQAVQCLTGPGQVARLVLER------ 1011
Query: 1463 KEHVPVTPQCTLSDQNAQGQGPEKVKKTTQV----KDYSFVTEENTFEVKLFKNSSGLGF 1518
VP + Q S ++ G V T + VT+ FEVKL KN++GLGF
Sbjct: 1012 --RVPRSTQQCPSANDSMGDERTAVSLVTALPGRPSSCVSVTDGPKFEVKLKKNANGLGF 1069
Query: 1519 SFSREDNLIPEQINASIVRVKKLFPGQPAAESGKIDVGDVILKVNGASLKGLSQQEVISA 1578
SF + + + + +VR+K+LFPGQPA E+G I GD+IL VNG S +GL QEV+
Sbjct: 1070 SFVQMEKESCSHLKSDLVRIKRLFPGQPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHL 1129
Query: 1579 LRGTAPEVFLLLCRPPPGVLPEIDTALLTPLQSPAQVLPNSSKDSSQPSCVEQSTSSDEN 1638
LRG EV LLLCRPPPG LPE++ TP S + K+ ++ +C + TS +
Sbjct: 1130 LRGAPQEVTLLLCRPPPGALPELEQEWQTPELS-------ADKEFTRATCTDSCTSPILD 1182
Query: 1639 EMSDKSKKQCKSPSRRDSYSDSSGSG 1664
+ S RDS S +G G
Sbjct: 1183 Q----------EDSWRDSASPDAGEG 1198
Score = 108 bits (271), Expect = 5e-23
Identities = 76/208 (36%), Positives = 115/208 (55%), Gaps = 33/208 (15%)
Query: 3 VSLAEALEVRGGPLQEEEIWAVLNQSAESLQELFRKVSLADPAALGFIISPWSLLLLPSG 62
V+LA AL+VRG L EEEIW++L +AE L E R S +++ PWS LL +G
Sbjct: 15 VTLASALQVRGEALSEEEIWSLLFLAAEQLLEDLRNDSS------DYVVCPWSALLSAAG 68
Query: 63 SVSFTDENISNQDLRAFTAPEVLQNQSLTSLSDVEKIHIYSLGMTLYWGADYEVPQSQPI 122
S+SF +S+ + F APE+LQ QS D + SQP+
Sbjct: 69 SLSFQGR-VSHIEAAPFKAPELLQGQS----------------------EDEQPDASQPL 105
Query: 123 KLGDHLNSILLGMCEDVIYARVSVRTVLDACSAHIRNSNC--APSFSYVKHLVKLVLGNL 180
+L + L+SILL MCED + R ++++VL+AC H + + AP+ +++ LV LVLG +
Sbjct: 106 QLCEPLHSILLTMCEDQPHRRCTLQSVLEACRVHEKEVSVYPAPAGLHIRRLVGLVLGTI 165
Query: 181 SGTDQ--LSCNSEQKPDRSQAIRDRLRG 206
S ++ + +S + +RS +R RLRG
Sbjct: 166 SEVEKRVVEESSSVQQNRSYLLRKRLRG 193
Score = 98.6 bits (244), Expect = 7e-20
Identities = 46/102 (45%), Positives = 71/102 (69%)
Query: 1078 HKRWSIVSSPEREITLVNLKKDAKYGLGFQIIGGEKMGRLDLGIFISSVAPGGPADLDGC 1137
++R S ++ P REI V LK+D G GF I GE G+ D GIFISS+ PGGPA+
Sbjct: 738 NRRKSFIAEPGREIVRVTLKRDPHRGFGFVINEGEYSGQADPGIFISSIIPGGPAEKAKT 797
Query: 1138 LKPGDRLISVNSVSLEGVSHHAAIEILQNAPEDVTLVISQPK 1179
+KPG +++++N +SLEG + + A+ ++QN+P+++ L+ISQ K
Sbjct: 798 IKPGGQILALNHISLEGFTFNMAVRMIQNSPDNIELIISQSK 839
Score = 70.9 bits (172), Expect = 2e-11
Identities = 77/298 (25%), Positives = 126/298 (42%), Gaps = 59/298 (19%)
Query: 1344 SVNTSNKMNF-KTFSSSPPKPGDIFEVELAKNDNSLGISVTVLFDKGGVNTSVRHGGIYV 1402
S++ +K N K+F + P + +I V L K D G + G + GI++
Sbjct: 730 SMHAGSKNNRRKSFIAEPGR--EIVRVTL-KRDPHRGFGFVI---NEGEYSGQADPGIFI 783
Query: 1403 KAVIPQGAAESDGRIHKGDRVLAVNGVSLEGATHKQAVETLRNTGQVVHLLLEK-----G 1457
++IP G AE I G ++LA+N +SLEG T AV ++N+ + L++ + G
Sbjct: 784 SSIIPGGPAEKAKTIKPGGQILALNHISLEGFTFNMAVRMIQNSPDNIELIISQSKGVGG 843
Query: 1458 QSP------TSKEHVPVTPQCTLSDQNAQGQGPEKVKKTTQVKD--------------YS 1497
+P T+ V T + Q + + + T+ D S
Sbjct: 844 NNPDEEKNSTANSGVSSTDILSFGYQGSLLSHTQDQDRNTEELDMAGVQSLVPRLRHQLS 903
Query: 1498 F----------------VTEENTFEVKLFKNSSGLGFSFSREDNLIPEQINASI----VR 1537
F ++ + V+L K LGFS + IN S+ +
Sbjct: 904 FLPLKGAGSSCPPSPPEISAGEIYFVELVKEDGTLGFS-------VTGGINTSVPYGGIY 956
Query: 1538 VKKLFPGQPAAESGKIDVGDVILKVNGASLKGLSQQEVISALRGTAPEVFLLLCRPPP 1595
VK + PG PAA+ G+I GD +L+V+G L GL+ ++ + L G L+L R P
Sbjct: 957 VKSIVPGGPAAKEGQILQGDRLLQVDGVILCGLTHKQAVQCLTGPGQVARLVLERRVP 1014
Score = 60.8 bits (146), Expect = 2e-08
Identities = 73/277 (26%), Positives = 110/277 (39%), Gaps = 50/277 (18%)
Query: 1791 ELLITLIKSEKGSLGFTVTKG-NQRI---GCYVHDVIQD-PAKSDGRLKPGDRLIKVNDT 1845
E+ + E G+LGF+VT G N + G YV ++ PA +G++ GDRL++V+
Sbjct: 925 EIYFVELVKEDGTLGFSVTGGINTSVPYGGIYVKSIVPGGPAAKEGQILQGDRLLQVDGV 984
Query: 1846 DVTNMTHTDAVNLLRAASKTVRLVIGR-------------------------VLELPRIP 1880
+ +TH AV L + RLV+ R V LP P
Sbjct: 985 ILCGLTHKQAVQCLTGPGQVARLVLERRVPRSTQQCPSANDSMGDERTAVSLVTALPGRP 1044
Query: 1881 MLPHLLPD-----ITLTCNKEELGFSL-------CGGHDSLYQVVYISDINPRSVAAIEG 1928
+ D + L N LGFS C S +V I + P A G
Sbjct: 1045 SSCVSVTDGPKFEVKLKKNANGLGFSFVQMEKESCSHLKS--DLVRIKRLFPGQPAEENG 1102
Query: 1929 NLQLLDVIHYVNGVSTQGMTLEEVNRALDMSLPSLVLKATRNDLPVVPSSKRS----AVS 1984
+ D+I VNG ST+G+ +EV L + + L R +P ++ +S
Sbjct: 1103 AIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCRPPPGALPELEQEWQTPELS 1162
Query: 1985 APKSTKGNGSYSVGSCSQPALTPNDSFSTVAGEEINE 2021
A K + + SC+ P L DS+ A + E
Sbjct: 1163 ADK--EFTRATCTDSCTSPILDQEDSWRDSASPDAGE 1197
Score = 56.2 bits (134), Expect = 4e-07
Identities = 36/101 (35%), Positives = 58/101 (57%), Gaps = 9/101 (8%)
Query: 1082 SIVSSPEREITLVNLKKDAKYGLGFQIIGGEKMG----RLDLGIFISSVAPGGPADLDGC 1137
S+ P+ E V LKK+A GLGF + EK + DL + I + PG PA+ +G
Sbjct: 1049 SVTDGPKFE---VKLKKNAN-GLGFSFVQMEKESCSHLKSDL-VRIKRLFPGQPAEENGA 1103
Query: 1138 LKPGDRLISVNSVSLEGVSHHAAIEILQNAPEDVTLVISQP 1178
+ GD +++VN S EG+ + +L+ AP++VTL++ +P
Sbjct: 1104 IAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCRP 1144
Score = 54.3 bits (129), Expect = 1e-06
Identities = 32/88 (36%), Positives = 48/88 (54%), Gaps = 1/88 (1%)
Query: 1090 EITLVNLKKDAKYGLGFQIIGGEKMGRLDLGIFISSVAPGGPADLDGCLKPGDRLISVNS 1149
EI V L K+ LGF + GG GI++ S+ PGGPA +G + GDRL+ V+
Sbjct: 925 EIYFVELVKEDGT-LGFSVTGGINTSVPYGGIYVKSIVPGGPAAKEGQILQGDRLLQVDG 983
Query: 1150 VSLEGVSHHAAIEILQNAPEDVTLVISQ 1177
V L G++H A++ L + LV+ +
Sbjct: 984 VILCGLTHKQAVQCLTGPGQVARLVLER 1011
Score = 32.7 bits (73), Expect = 4.6
Identities = 18/84 (21%), Positives = 39/84 (46%), Gaps = 5/84 (5%)
Query: 1794 ITLIKSEKGSLGFTVTKGNQR----IGCYVHDVIQD-PAKSDGRLKPGDRLIKVNDTDVT 1848
+TL + GF + +G G ++ +I PA+ +KPG +++ +N +
Sbjct: 754 VTLKRDPHRGFGFVINEGEYSGQADPGIFISSIIPGGPAEKAKTIKPGGQILALNHISLE 813
Query: 1849 NMTHTDAVNLLRAASKTVRLVIGR 1872
T AV +++ + + L+I +
Sbjct: 814 GFTFNMAVRMIQNSPDNIELIISQ 837
>gi|110346436 FERM and PDZ domain containing 2 isoform 3 [Homo
sapiens]
Length = 1309
Score = 297 bits (761), Expect = 8e-80
Identities = 157/340 (46%), Positives = 225/340 (66%), Gaps = 4/340 (1%)
Query: 538 FFGPEFVKMTIEPFISLDLPRSILTKKGKNEDNRRKVNIMLLNGQRLELTCDTKTICKDV 597
F PEF+ + E ++L LP S++TKKGK+ R + ++LLNGQ LE+ CD ++ V
Sbjct: 308 FSRPEFILLAGEAPMTLHLPGSVVTKKGKSYLALRDLCVVLLNGQHLEVKCDVESTVGAV 367
Query: 598 FDMVVAHIGLVEHHLFALATLKDNEYFFVDPDLKLTKVAPEGWKEEPKKKTKATVNFTLF 657
F+ V + L E F LA +K E+FF+D + +L K+APEGW+E+P+K + T FTLF
Sbjct: 368 FNAVTSFANLEELTYFGLAYMKSKEFFFLDSETRLCKIAPEGWREQPQKTSMNT--FTLF 425
Query: 658 FRIKFFMDDVSLIQHTLTCHQYYLQLRKDILEERMHCDDETSLLLASLALQAEYGDYQPE 717
RIKFF+ L+QH+LT HQ+YLQLRKDILEER++C++E L L LALQAE+G+Y E
Sbjct: 426 LRIKFFVSHYGLLQHSLTRHQFYLQLRKDILEERLYCNEEILLQLGVLALQAEFGNYPKE 485
Query: 718 -VHGVSYFRMEHYLPARVMEKLDLSYIKEELPKLHNTYVGASEKETELEFLKVCQRLTEY 776
V YF +E Y+PA ++E++ ++ E+ ++H ++ EL+FL+V Q+L EY
Sbjct: 486 QVESKPYFHVEDYIPASLIERMTALRVQVEVSEMHRLSSALWGEDAELKFLRVTQQLPEY 545
Query: 777 GVHFHRVHPEK-KSQTGILLGVCSKGVLVFEVHNGVRTLVLRFPWRETKKISFSKKKITL 835
GV H+V EK + + + LG+C+KGV+V+EV N R +LRF WRET KIS +KK T+
Sbjct: 546 GVLVHQVFSEKRRPEEEMALGICAKGVIVYEVKNNSRIAMLRFQWRETGKISTYQKKFTI 605
Query: 836 QNTSDGIKHGFQTDNSKICQYLLHLCSYQHKFQLQMRARQ 875
++ G KH F TD++K +YLL LCS QH F QM + Q
Sbjct: 606 TSSVTGKKHTFVTDSAKTSKYLLDLCSAQHGFNAQMGSGQ 645
Score = 214 bits (545), Expect = 8e-55
Identities = 144/386 (37%), Positives = 205/386 (53%), Gaps = 53/386 (13%)
Query: 1298 DSNQSKTKKPGIS--DVTDYSDRGDSDMDEATYSSSQDHQTPKQESSSSVNTSNKMNFKT 1355
D ++ T G+S D+ + +G +++ QD T + + + + ++ +
Sbjct: 869 DEEKNSTANSGVSSTDILSFGYQGSL----LSHTQDQDRNTEELDMAGVQSLVPRLRHQL 924
Query: 1356 F--------SSSPPKP-----GDIFEVELAKNDNSLGISVTVLFDKGGVNTSVRHGGIYV 1402
SS PP P G+I+ VEL K D +LG SVT GG+NTSV +GGIYV
Sbjct: 925 SFLPLKGAGSSCPPSPPEISAGEIYFVELVKEDGTLGFSVT-----GGINTSVPYGGIYV 979
Query: 1403 KAVIPQGAAESDGRIHKGDRVLAVNGVSLEGATHKQAVETLRNTGQVVHLLLEKGQSPTS 1462
K+++P G A +G+I +GDR+L V+GV L G THKQAV+ L GQV L+LE+
Sbjct: 980 KSIVPGGPAAKEGQILQGDRLLQVDGVILCGLTHKQAVQCLTGPGQVARLVLER------ 1033
Query: 1463 KEHVPVTPQCTLSDQNAQGQGPEKVKKTTQV----KDYSFVTEENTFEVKLFKNSSGLGF 1518
VP + Q S ++ G V T + VT+ FEVKL KN++GLGF
Sbjct: 1034 --RVPRSTQQCPSANDSMGDERTAVSLVTALPGRPSSCVSVTDGPKFEVKLKKNANGLGF 1091
Query: 1519 SFSREDNLIPEQINASIVRVKKLFPGQPAAESGKIDVGDVILKVNGASLKGLSQQEVISA 1578
SF + + + + +VR+K+LFPGQPA E+G I GD+IL VNG S +GL QEV+
Sbjct: 1092 SFVQMEKESCSHLKSDLVRIKRLFPGQPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHL 1151
Query: 1579 LRGTAPEVFLLLCRPPPGVLPEIDTALLTPLQSPAQVLPNSSKDSSQPSCVEQSTSSDEN 1638
LRG EV LLLCRPPPG LPE++ TP S + K+ ++ +C + TS +
Sbjct: 1152 LRGAPQEVTLLLCRPPPGALPELEQEWQTPELS-------ADKEFTRATCTDSCTSPILD 1204
Query: 1639 EMSDKSKKQCKSPSRRDSYSDSSGSG 1664
+ S RDS S +G G
Sbjct: 1205 Q----------EDSWRDSASPDAGEG 1220
Score = 150 bits (379), Expect = 2e-35
Identities = 88/208 (42%), Positives = 130/208 (62%), Gaps = 11/208 (5%)
Query: 3 VSLAEALEVRGGPLQEEEIWAVLNQSAESLQELFRKVSLADPAALGFIISPWSLLLLPSG 62
V+LA AL+VRG L EEEIW++L +AE L E R S +++ PWS LL +G
Sbjct: 15 VTLASALQVRGEALSEEEIWSLLFLAAEQLLEDLRNDSS------DYVVCPWSALLSAAG 68
Query: 63 SVSFTDENISNQDLRAFTAPEVLQNQSLTSLSDVEKIHIYSLGMTLYWGADYEVPQSQPI 122
S+SF +S+ + F APE+LQ QS D ++H+YSLGMTLYW A + VP QP+
Sbjct: 69 SLSFQGR-VSHIEAAPFKAPELLQGQSEDEQPDASQMHVYSLGMTLYWSAGFHVPPHQPL 127
Query: 123 KLGDHLNSILLGMCEDVIYARVSVRTVLDACSAHIRNSNC--APSFSYVKHLVKLVLGNL 180
+L + L+SILL MCED + R ++++VL+AC H + + AP+ +++ LV LVLG +
Sbjct: 128 QLCEPLHSILLTMCEDQPHRRCTLQSVLEACRVHEKEVSVYPAPAGLHIRRLVGLVLGTI 187
Query: 181 SGTDQ--LSCNSEQKPDRSQAIRDRLRG 206
S ++ + +S + +RS +R RLRG
Sbjct: 188 SEVEKRVVEESSSVQQNRSYLLRKRLRG 215
Score = 98.6 bits (244), Expect = 7e-20
Identities = 46/102 (45%), Positives = 71/102 (69%)
Query: 1078 HKRWSIVSSPEREITLVNLKKDAKYGLGFQIIGGEKMGRLDLGIFISSVAPGGPADLDGC 1137
++R S ++ P REI V LK+D G GF I GE G+ D GIFISS+ PGGPA+
Sbjct: 760 NRRKSFIAEPGREIVRVTLKRDPHRGFGFVINEGEYSGQADPGIFISSIIPGGPAEKAKT 819
Query: 1138 LKPGDRLISVNSVSLEGVSHHAAIEILQNAPEDVTLVISQPK 1179
+KPG +++++N +SLEG + + A+ ++QN+P+++ L+ISQ K
Sbjct: 820 IKPGGQILALNHISLEGFTFNMAVRMIQNSPDNIELIISQSK 861
Score = 70.9 bits (172), Expect = 2e-11
Identities = 77/298 (25%), Positives = 126/298 (42%), Gaps = 59/298 (19%)
Query: 1344 SVNTSNKMNF-KTFSSSPPKPGDIFEVELAKNDNSLGISVTVLFDKGGVNTSVRHGGIYV 1402
S++ +K N K+F + P + +I V L K D G + G + GI++
Sbjct: 752 SMHAGSKNNRRKSFIAEPGR--EIVRVTL-KRDPHRGFGFVI---NEGEYSGQADPGIFI 805
Query: 1403 KAVIPQGAAESDGRIHKGDRVLAVNGVSLEGATHKQAVETLRNTGQVVHLLLEK-----G 1457
++IP G AE I G ++LA+N +SLEG T AV ++N+ + L++ + G
Sbjct: 806 SSIIPGGPAEKAKTIKPGGQILALNHISLEGFTFNMAVRMIQNSPDNIELIISQSKGVGG 865
Query: 1458 QSP------TSKEHVPVTPQCTLSDQNAQGQGPEKVKKTTQVKD--------------YS 1497
+P T+ V T + Q + + + T+ D S
Sbjct: 866 NNPDEEKNSTANSGVSSTDILSFGYQGSLLSHTQDQDRNTEELDMAGVQSLVPRLRHQLS 925
Query: 1498 F----------------VTEENTFEVKLFKNSSGLGFSFSREDNLIPEQINASI----VR 1537
F ++ + V+L K LGFS + IN S+ +
Sbjct: 926 FLPLKGAGSSCPPSPPEISAGEIYFVELVKEDGTLGFS-------VTGGINTSVPYGGIY 978
Query: 1538 VKKLFPGQPAAESGKIDVGDVILKVNGASLKGLSQQEVISALRGTAPEVFLLLCRPPP 1595
VK + PG PAA+ G+I GD +L+V+G L GL+ ++ + L G L+L R P
Sbjct: 979 VKSIVPGGPAAKEGQILQGDRLLQVDGVILCGLTHKQAVQCLTGPGQVARLVLERRVP 1036
Score = 60.8 bits (146), Expect = 2e-08
Identities = 73/277 (26%), Positives = 110/277 (39%), Gaps = 50/277 (18%)
Query: 1791 ELLITLIKSEKGSLGFTVTKG-NQRI---GCYVHDVIQD-PAKSDGRLKPGDRLIKVNDT 1845
E+ + E G+LGF+VT G N + G YV ++ PA +G++ GDRL++V+
Sbjct: 947 EIYFVELVKEDGTLGFSVTGGINTSVPYGGIYVKSIVPGGPAAKEGQILQGDRLLQVDGV 1006
Query: 1846 DVTNMTHTDAVNLLRAASKTVRLVIGR-------------------------VLELPRIP 1880
+ +TH AV L + RLV+ R V LP P
Sbjct: 1007 ILCGLTHKQAVQCLTGPGQVARLVLERRVPRSTQQCPSANDSMGDERTAVSLVTALPGRP 1066
Query: 1881 MLPHLLPD-----ITLTCNKEELGFSL-------CGGHDSLYQVVYISDINPRSVAAIEG 1928
+ D + L N LGFS C S +V I + P A G
Sbjct: 1067 SSCVSVTDGPKFEVKLKKNANGLGFSFVQMEKESCSHLKS--DLVRIKRLFPGQPAEENG 1124
Query: 1929 NLQLLDVIHYVNGVSTQGMTLEEVNRALDMSLPSLVLKATRNDLPVVPSSKRS----AVS 1984
+ D+I VNG ST+G+ +EV L + + L R +P ++ +S
Sbjct: 1125 AIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCRPPPGALPELEQEWQTPELS 1184
Query: 1985 APKSTKGNGSYSVGSCSQPALTPNDSFSTVAGEEINE 2021
A K + + SC+ P L DS+ A + E
Sbjct: 1185 ADK--EFTRATCTDSCTSPILDQEDSWRDSASPDAGE 1219
Score = 56.2 bits (134), Expect = 4e-07
Identities = 36/101 (35%), Positives = 58/101 (57%), Gaps = 9/101 (8%)
Query: 1082 SIVSSPEREITLVNLKKDAKYGLGFQIIGGEKMG----RLDLGIFISSVAPGGPADLDGC 1137
S+ P+ E V LKK+A GLGF + EK + DL + I + PG PA+ +G
Sbjct: 1071 SVTDGPKFE---VKLKKNAN-GLGFSFVQMEKESCSHLKSDL-VRIKRLFPGQPAEENGA 1125
Query: 1138 LKPGDRLISVNSVSLEGVSHHAAIEILQNAPEDVTLVISQP 1178
+ GD +++VN S EG+ + +L+ AP++VTL++ +P
Sbjct: 1126 IAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCRP 1166
Score = 54.3 bits (129), Expect = 1e-06
Identities = 32/88 (36%), Positives = 48/88 (54%), Gaps = 1/88 (1%)
Query: 1090 EITLVNLKKDAKYGLGFQIIGGEKMGRLDLGIFISSVAPGGPADLDGCLKPGDRLISVNS 1149
EI V L K+ LGF + GG GI++ S+ PGGPA +G + GDRL+ V+
Sbjct: 947 EIYFVELVKEDGT-LGFSVTGGINTSVPYGGIYVKSIVPGGPAAKEGQILQGDRLLQVDG 1005
Query: 1150 VSLEGVSHHAAIEILQNAPEDVTLVISQ 1177
V L G++H A++ L + LV+ +
Sbjct: 1006 VILCGLTHKQAVQCLTGPGQVARLVLER 1033
Score = 32.7 bits (73), Expect = 4.6
Identities = 18/84 (21%), Positives = 39/84 (46%), Gaps = 5/84 (5%)
Query: 1794 ITLIKSEKGSLGFTVTKGNQR----IGCYVHDVIQD-PAKSDGRLKPGDRLIKVNDTDVT 1848
+TL + GF + +G G ++ +I PA+ +KPG +++ +N +
Sbjct: 776 VTLKRDPHRGFGFVINEGEYSGQADPGIFISSIIPGGPAEKAKTIKPGGQILALNHISLE 835
Query: 1849 NMTHTDAVNLLRAASKTVRLVIGR 1872
T AV +++ + + L+I +
Sbjct: 836 GFTFNMAVRMIQNSPDNIELIISQ 859
>gi|109138573 protein tyrosine phosphatase, non-receptor type 20A
isoform 8 [Homo sapiens]
Length = 339
Score = 239 bits (609), Expect = 3e-62
Identities = 117/240 (48%), Positives = 156/240 (65%), Gaps = 1/240 (0%)
Query: 2237 GQTKENRRKNRYKNILPYDATRVPLGDEGGYINASFIKIPVGKEEFVYIACQGPLPTTVG 2296
G NR KNRY++ILPYD+TRVPLG YINAS+I+I EE+ YIA QGPL +T+
Sbjct: 97 GNQPSNREKNRYRDILPYDSTRVPLGKSKDYINASYIRIVNCGEEYFYIATQGPLLSTID 156
Query: 2297 DFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSNRLRLALVRMQQLKGFV 2356
DFWQM+ E S VIAM+T+E+EG IKC YWP L K + + R+ L Q L+ F+
Sbjct: 157 DFWQMVLENNSNVIAMITREIEGGIIKCYHYWPISLKKPLELKH-FRVFLENYQILQYFI 215
Query: 2357 VRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYMRHIHRSGPIITHCSAG 2416
+R + + T + L FT WPDH TP+ D + +I Y R H +GP++ HCSAG
Sbjct: 216 IRMFQVVEKSTGTSHSVKQLQFTKWPDHGTPASADSFIKYIRYARKSHLTGPMVVHCSAG 275
Query: 2417 IGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTEDQYIFCYQVILYVLTRL 2476
IGR+G +C+DVV I ++ F+I D+V MR QR GMVQT++QY FCY ++L VL +L
Sbjct: 276 IGRTGVFLCVDVVFCAIVKNCSFNIMDIVAQMREQRSGMVQTKEQYHFCYDIVLEVLRKL 335
>gi|109138561 protein tyrosine phosphatase, non-receptor type 20A
isoform 3 [Homo sapiens]
Length = 411
Score = 239 bits (609), Expect = 3e-62
Identities = 117/240 (48%), Positives = 156/240 (65%), Gaps = 1/240 (0%)
Query: 2237 GQTKENRRKNRYKNILPYDATRVPLGDEGGYINASFIKIPVGKEEFVYIACQGPLPTTVG 2296
G NR KNRY++ILPYD+TRVPLG YINAS+I+I EE+ YIA QGPL +T+
Sbjct: 169 GNQPSNREKNRYRDILPYDSTRVPLGKSKDYINASYIRIVNCGEEYFYIATQGPLLSTID 228
Query: 2297 DFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSNRLRLALVRMQQLKGFV 2356
DFWQM+ E S VIAM+T+E+EG IKC YWP L K + + R+ L Q L+ F+
Sbjct: 229 DFWQMVLENNSNVIAMITREIEGGIIKCYHYWPISLKKPLELKH-FRVFLENYQILQYFI 287
Query: 2357 VRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYMRHIHRSGPIITHCSAG 2416
+R + + T + L FT WPDH TP+ D + +I Y R H +GP++ HCSAG
Sbjct: 288 IRMFQVVEKSTGTSHSVKQLQFTKWPDHGTPASADSFIKYIRYARKSHLTGPMVVHCSAG 347
Query: 2417 IGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTEDQYIFCYQVILYVLTRL 2476
IGR+G +C+DVV I ++ F+I D+V MR QR GMVQT++QY FCY ++L VL +L
Sbjct: 348 IGRTGVFLCVDVVFCAIVKNCSFNIMDIVAQMREQRSGMVQTKEQYHFCYDIVLEVLRKL 407
>gi|109138557 protein tyrosine phosphatase, non-receptor type 20A
isoform 1 [Homo sapiens]
Length = 420
Score = 239 bits (609), Expect = 3e-62
Identities = 117/240 (48%), Positives = 156/240 (65%), Gaps = 1/240 (0%)
Query: 2237 GQTKENRRKNRYKNILPYDATRVPLGDEGGYINASFIKIPVGKEEFVYIACQGPLPTTVG 2296
G NR KNRY++ILPYD+TRVPLG YINAS+I+I EE+ YIA QGPL +T+
Sbjct: 178 GNQPSNREKNRYRDILPYDSTRVPLGKSKDYINASYIRIVNCGEEYFYIATQGPLLSTID 237
Query: 2297 DFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSNRLRLALVRMQQLKGFV 2356
DFWQM+ E S VIAM+T+E+EG IKC YWP L K + + R+ L Q L+ F+
Sbjct: 238 DFWQMVLENNSNVIAMITREIEGGIIKCYHYWPISLKKPLELKH-FRVFLENYQILQYFI 296
Query: 2357 VRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYMRHIHRSGPIITHCSAG 2416
+R + + T + L FT WPDH TP+ D + +I Y R H +GP++ HCSAG
Sbjct: 297 IRMFQVVEKSTGTSHSVKQLQFTKWPDHGTPASADSFIKYIRYARKSHLTGPMVVHCSAG 356
Query: 2417 IGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTEDQYIFCYQVILYVLTRL 2476
IGR+G +C+DVV I ++ F+I D+V MR QR GMVQT++QY FCY ++L VL +L
Sbjct: 357 IGRTGVFLCVDVVFCAIVKNCSFNIMDIVAQMREQRSGMVQTKEQYHFCYDIVLEVLRKL 416
>gi|108802617 protein tyrosine phosphatase, non-receptor type 20
isoform 8 [Homo sapiens]
Length = 339
Score = 239 bits (609), Expect = 3e-62
Identities = 117/240 (48%), Positives = 156/240 (65%), Gaps = 1/240 (0%)
Query: 2237 GQTKENRRKNRYKNILPYDATRVPLGDEGGYINASFIKIPVGKEEFVYIACQGPLPTTVG 2296
G NR KNRY++ILPYD+TRVPLG YINAS+I+I EE+ YIA QGPL +T+
Sbjct: 97 GNQPSNREKNRYRDILPYDSTRVPLGKSKDYINASYIRIVNCGEEYFYIATQGPLLSTID 156
Query: 2297 DFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSNRLRLALVRMQQLKGFV 2356
DFWQM+ E S VIAM+T+E+EG IKC YWP L K + + R+ L Q L+ F+
Sbjct: 157 DFWQMVLENNSNVIAMITREIEGGIIKCYHYWPISLKKPLELKH-FRVFLENYQILQYFI 215
Query: 2357 VRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYMRHIHRSGPIITHCSAG 2416
+R + + T + L FT WPDH TP+ D + +I Y R H +GP++ HCSAG
Sbjct: 216 IRMFQVVEKSTGTSHSVKQLQFTKWPDHGTPASADSFIKYIRYARKSHLTGPMVVHCSAG 275
Query: 2417 IGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTEDQYIFCYQVILYVLTRL 2476
IGR+G +C+DVV I ++ F+I D+V MR QR GMVQT++QY FCY ++L VL +L
Sbjct: 276 IGRTGVFLCVDVVFCAIVKNCSFNIMDIVAQMREQRSGMVQTKEQYHFCYDIVLEVLRKL 335
>gi|108802607 protein tyrosine phosphatase, non-receptor type 20
isoform 3 [Homo sapiens]
Length = 411
Score = 239 bits (609), Expect = 3e-62
Identities = 117/240 (48%), Positives = 156/240 (65%), Gaps = 1/240 (0%)
Query: 2237 GQTKENRRKNRYKNILPYDATRVPLGDEGGYINASFIKIPVGKEEFVYIACQGPLPTTVG 2296
G NR KNRY++ILPYD+TRVPLG YINAS+I+I EE+ YIA QGPL +T+
Sbjct: 169 GNQPSNREKNRYRDILPYDSTRVPLGKSKDYINASYIRIVNCGEEYFYIATQGPLLSTID 228
Query: 2297 DFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSNRLRLALVRMQQLKGFV 2356
DFWQM+ E S VIAM+T+E+EG IKC YWP L K + + R+ L Q L+ F+
Sbjct: 229 DFWQMVLENNSNVIAMITREIEGGIIKCYHYWPISLKKPLELKH-FRVFLENYQILQYFI 287
Query: 2357 VRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYMRHIHRSGPIITHCSAG 2416
+R + + T + L FT WPDH TP+ D + +I Y R H +GP++ HCSAG
Sbjct: 288 IRMFQVVEKSTGTSHSVKQLQFTKWPDHGTPASADSFIKYIRYARKSHLTGPMVVHCSAG 347
Query: 2417 IGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTEDQYIFCYQVILYVLTRL 2476
IGR+G +C+DVV I ++ F+I D+V MR QR GMVQT++QY FCY ++L VL +L
Sbjct: 348 IGRTGVFLCVDVVFCAIVKNCSFNIMDIVAQMREQRSGMVQTKEQYHFCYDIVLEVLRKL 407
>gi|108802604 protein tyrosine phosphatase, non-receptor type 20
isoform 1 [Homo sapiens]
Length = 420
Score = 239 bits (609), Expect = 3e-62
Identities = 117/240 (48%), Positives = 156/240 (65%), Gaps = 1/240 (0%)
Query: 2237 GQTKENRRKNRYKNILPYDATRVPLGDEGGYINASFIKIPVGKEEFVYIACQGPLPTTVG 2296
G NR KNRY++ILPYD+TRVPLG YINAS+I+I EE+ YIA QGPL +T+
Sbjct: 178 GNQPSNREKNRYRDILPYDSTRVPLGKSKDYINASYIRIVNCGEEYFYIATQGPLLSTID 237
Query: 2297 DFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSNRLRLALVRMQQLKGFV 2356
DFWQM+ E S VIAM+T+E+EG IKC YWP L K + + R+ L Q L+ F+
Sbjct: 238 DFWQMVLENNSNVIAMITREIEGGIIKCYHYWPISLKKPLELKH-FRVFLENYQILQYFI 296
Query: 2357 VRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYMRHIHRSGPIITHCSAG 2416
+R + + T + L FT WPDH TP+ D + +I Y R H +GP++ HCSAG
Sbjct: 297 IRMFQVVEKSTGTSHSVKQLQFTKWPDHGTPASADSFIKYIRYARKSHLTGPMVVHCSAG 356
Query: 2417 IGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTEDQYIFCYQVILYVLTRL 2476
IGR+G +C+DVV I ++ F+I D+V MR QR GMVQT++QY FCY ++L VL +L
Sbjct: 357 IGRTGVFLCVDVVFCAIVKNCSFNIMDIVAQMREQRSGMVQTKEQYHFCYDIVLEVLRKL 416
>gi|108802611 protein tyrosine phosphatase, non-receptor type 20
isoform 5 [Homo sapiens]
Length = 228
Score = 214 bits (546), Expect = 7e-55
Identities = 106/222 (47%), Positives = 143/222 (64%), Gaps = 1/222 (0%)
Query: 2255 DATRVPLGDEGGYINASFIKIPVGKEEFVYIACQGPLPTTVGDFWQMIWEQKSTVIAMMT 2314
D+TRVPLG YINAS+I+I EE+ YIA QGPL +T+ DFWQM+ E S VIAM+T
Sbjct: 4 DSTRVPLGKSKDYINASYIRIVNCGEEYFYIATQGPLLSTIDDFWQMVLENNSNVIAMIT 63
Query: 2315 QEVEGEKIKCQRYWPNILGKTTMVSNRLRLALVRMQQLKGFVVRAMTLEDIQTREVRHIS 2374
+E+EG IKC YWP L K + + R+ L Q L+ F++R + + T +
Sbjct: 64 REIEGGIIKCYHYWPISLKKPLELKH-FRVFLENYQILQYFIIRMFQVVEKSTGTSHSVK 122
Query: 2375 HLNFTAWPDHDTPSQPDDLLTFISYMRHIHRSGPIITHCSAGIGRSGTLICIDVVLGLIS 2434
L FT WPDH TP+ D + +I Y R H +GP++ HCSAGIGR+G +C+DVV I
Sbjct: 123 QLQFTKWPDHGTPASADSFIKYIRYARKSHLTGPMVVHCSAGIGRTGVFLCVDVVFCAIV 182
Query: 2435 QDLDFDISDLVRCMRLQRHGMVQTEDQYIFCYQVILYVLTRL 2476
++ F+I D+V MR QR GMVQT++QY FCY ++L VL +L
Sbjct: 183 KNCSFNIMDIVAQMREQRSGMVQTKEQYHFCYDIVLEVLRKL 224
>gi|109138565 protein tyrosine phosphatase, non-receptor type 20A
isoform 5 [Homo sapiens]
Length = 228
Score = 214 bits (546), Expect = 7e-55
Identities = 106/222 (47%), Positives = 143/222 (64%), Gaps = 1/222 (0%)
Query: 2255 DATRVPLGDEGGYINASFIKIPVGKEEFVYIACQGPLPTTVGDFWQMIWEQKSTVIAMMT 2314
D+TRVPLG YINAS+I+I EE+ YIA QGPL +T+ DFWQM+ E S VIAM+T
Sbjct: 4 DSTRVPLGKSKDYINASYIRIVNCGEEYFYIATQGPLLSTIDDFWQMVLENNSNVIAMIT 63
Query: 2315 QEVEGEKIKCQRYWPNILGKTTMVSNRLRLALVRMQQLKGFVVRAMTLEDIQTREVRHIS 2374
+E+EG IKC YWP L K + + R+ L Q L+ F++R + + T +
Sbjct: 64 REIEGGIIKCYHYWPISLKKPLELKH-FRVFLENYQILQYFIIRMFQVVEKSTGTSHSVK 122
Query: 2375 HLNFTAWPDHDTPSQPDDLLTFISYMRHIHRSGPIITHCSAGIGRSGTLICIDVVLGLIS 2434
L FT WPDH TP+ D + +I Y R H +GP++ HCSAGIGR+G +C+DVV I
Sbjct: 123 QLQFTKWPDHGTPASADSFIKYIRYARKSHLTGPMVVHCSAGIGRTGVFLCVDVVFCAIV 182
Query: 2435 QDLDFDISDLVRCMRLQRHGMVQTEDQYIFCYQVILYVLTRL 2476
++ F+I D+V MR QR GMVQT++QY FCY ++L VL +L
Sbjct: 183 KNCSFNIMDIVAQMREQRSGMVQTKEQYHFCYDIVLEVLRKL 224
>gi|241896926 protein tyrosine phosphatase, receptor type, H isoform 2
precursor [Homo sapiens]
Length = 937
Score = 194 bits (492), Expect = 1e-48
Identities = 107/261 (40%), Positives = 150/261 (57%), Gaps = 13/261 (4%)
Query: 2235 LIGQTKENRRKNRYKNILPYDATRVPLG---DEGG--YINASFIKIPVGKEEFVYIACQG 2289
++ EN KNRY+N+LPYD +RVPL +E G YINASF+ +EF IA QG
Sbjct: 659 MVASASENNAKNRYRNVLPYDWSRVPLKPIHEEPGSDYINASFMPGLWSPQEF--IATQG 716
Query: 2290 PLPTTVGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSNRLRLALVRM 2349
PLP TVGDFW+++WEQ+S + M+T +E ++KC+ YWP L LR+ LV
Sbjct: 717 PLPQTVGDFWRLVWEQQSHTLVMLTNCMEAGRVKCEHYWP--LDSQPCTHGHLRVTLVGE 774
Query: 2350 QQLKGFVVRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYMR----HIHR 2405
+ ++ + VR + L ++ ++ + ++ AWPDH PS PD LL F +R
Sbjct: 775 EVMENWTVRELLLLQVEEQKTLSVRQFHYQAWPDHGVPSSPDTLLAFWRMLRQWLDQTME 834
Query: 2406 SGPIITHCSAGIGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTEDQYIFC 2465
GP I HCSAG+GR+GTLI +DV+L + + VR MR R MVQTE QY+F
Sbjct: 835 GGPPIVHCSAGVGRTGTLIALDVLLRQLQSEGLLGPFSFVRKMRESRPLMVQTEAQYVFL 894
Query: 2466 YQVILYVLTRLQAEEEQKQQP 2486
+Q IL L + +K+ P
Sbjct: 895 HQCILRFLQQSAQAPAEKEVP 915
>gi|241896924 protein tyrosine phosphatase, receptor type, H isoform 1
precursor [Homo sapiens]
Length = 1115
Score = 194 bits (492), Expect = 1e-48
Identities = 107/261 (40%), Positives = 150/261 (57%), Gaps = 13/261 (4%)
Query: 2235 LIGQTKENRRKNRYKNILPYDATRVPLG---DEGG--YINASFIKIPVGKEEFVYIACQG 2289
++ EN KNRY+N+LPYD +RVPL +E G YINASF+ +EF IA QG
Sbjct: 837 MVASASENNAKNRYRNVLPYDWSRVPLKPIHEEPGSDYINASFMPGLWSPQEF--IATQG 894
Query: 2290 PLPTTVGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSNRLRLALVRM 2349
PLP TVGDFW+++WEQ+S + M+T +E ++KC+ YWP L LR+ LV
Sbjct: 895 PLPQTVGDFWRLVWEQQSHTLVMLTNCMEAGRVKCEHYWP--LDSQPCTHGHLRVTLVGE 952
Query: 2350 QQLKGFVVRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYMR----HIHR 2405
+ ++ + VR + L ++ ++ + ++ AWPDH PS PD LL F +R
Sbjct: 953 EVMENWTVRELLLLQVEEQKTLSVRQFHYQAWPDHGVPSSPDTLLAFWRMLRQWLDQTME 1012
Query: 2406 SGPIITHCSAGIGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTEDQYIFC 2465
GP I HCSAG+GR+GTLI +DV+L + + VR MR R MVQTE QY+F
Sbjct: 1013 GGPPIVHCSAGVGRTGTLIALDVLLRQLQSEGLLGPFSFVRKMRESRPLMVQTEAQYVFL 1072
Query: 2466 YQVILYVLTRLQAEEEQKQQP 2486
+Q IL L + +K+ P
Sbjct: 1073 HQCILRFLQQSAQAPAEKEVP 1093
>gi|223941891 protein tyrosine phosphatase, non-receptor type 3
isoform 6 [Homo sapiens]
Length = 581
Score = 190 bits (482), Expect = 2e-47
Identities = 110/299 (36%), Positives = 156/299 (52%), Gaps = 5/299 (1%)
Query: 2177 FLTNDELAVLPVVKVLPSGKYTGANLKSVIRVLRGLLDQGIPSKELENLQELKPLDQCLI 2236
F + DEL L + P G L+ + L+ L+ G + E L KP
Sbjct: 273 FKSEDELNQLFPEAIFPMCPEGGDTLEGSMAQLKKGLESGTVLIQFEQLYRKKPGLAITF 332
Query: 2237 GQTKENRRKNRYKNILPYDATRVPLGDEGGYINASFIKIPVGKEEFV--YIACQGPLPTT 2294
+ +N KNRYK++LPYD TRV L YINAS++ + + V YIA QGPLP T
Sbjct: 333 AKLPQNLDKNRYKDVLPYDTTRVLLQGNEDYINASYVNMEIPAANLVNKYIATQGPLPHT 392
Query: 2295 VGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSNRLRLALVRMQQLKG 2354
FWQ++W+QK ++I M+T E + KC +YWP+ M +
Sbjct: 393 CAQFWQVVWDQKLSLIVMLTTLTERGRTKCHQYWPD--PPDVMNHGGFHIQCQSEDCTIA 450
Query: 2355 FVVRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYMRHIH-RSGPIITHC 2413
+V R M + + QT E ++HL + AWPDH P D L F++Y+R + S P++ HC
Sbjct: 451 YVSREMLVTNTQTGEEHTVTHLQYVAWPDHGVPDDSSDFLEFVNYVRSLRVDSEPVLVHC 510
Query: 2414 SAGIGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTEDQYIFCYQVILYV 2472
SAGIGR+G L+ ++ + L ++L D+VR MR QR MVQT QY F + IL V
Sbjct: 511 SAGIGRTGVLVTMETAMCLTERNLPIYPLDIVRKMRDQRAMMVQTSSQYKFVCEAILRV 569
Score = 39.7 bits (91), Expect = 0.037
Identities = 56/256 (21%), Positives = 103/256 (40%), Gaps = 34/256 (13%)
Query: 1630 EQSTSSDENEMSDKSKKQCKSPSRRDSYSDSSGSGEDDL------VTAPANISNSTWSSA 1683
E++ S M ++ K+ +SP R S D+L +T ++ + S
Sbjct: 30 EKNVLSQYWTMGSRNTKK-RSPRLRHEIRKPRHSSADNLANEMTYITETEDVFYTYKGSL 88
Query: 1684 LHQTLSNMVSQAQSHHEAPKSQEDTICTMFYYPQKIPNKPEFEDSNPSPLPPDMAPGQSY 1743
Q + VSQ +S H+ S+ + Y QK S+ S P APG
Sbjct: 89 APQDSDSEVSQNRSPHQESLSENNP--AQSYLTQK---------SSSSVSPSSNAPGSC- 136
Query: 1744 QPQSESASSSSMDKYHIHHISEPTRQENWTPLKNDLENHLEDFELEVELLITLIKSEKGS 1803
+ +D +H +++ E+ + D ++ + + + LI + E G
Sbjct: 137 --SPDGVDQQLLDDFH--RVTKGGSTEDASQYYCDKNDNGDSYLV----LIRITPDEDGK 188
Query: 1804 LGFTVTKGNQRIGCYVHDVIQDPAKSDG---RLKPGDRLIKVNDTDVTNMTHTDAVNLLR 1860
GF + G + V I + +D +L GD+++ +N D++ TH V ++
Sbjct: 189 FGFNLKGGVDQKMPLVVSRINPESPADTCIPKLNEGDQIVLINGRDISEHTHDQVVMFIK 248
Query: 1861 AA----SKTVRLVIGR 1872
A+ S+ + LVI R
Sbjct: 249 ASRESHSRELALVIRR 264
>gi|223941888 protein tyrosine phosphatase, non-receptor type 3
isoform 5 [Homo sapiens]
Length = 626
Score = 190 bits (482), Expect = 2e-47
Identities = 110/299 (36%), Positives = 156/299 (52%), Gaps = 5/299 (1%)
Query: 2177 FLTNDELAVLPVVKVLPSGKYTGANLKSVIRVLRGLLDQGIPSKELENLQELKPLDQCLI 2236
F + DEL L + P G L+ + L+ L+ G + E L KP
Sbjct: 318 FKSEDELNQLFPEAIFPMCPEGGDTLEGSMAQLKKGLESGTVLIQFEQLYRKKPGLAITF 377
Query: 2237 GQTKENRRKNRYKNILPYDATRVPLGDEGGYINASFIKIPVGKEEFV--YIACQGPLPTT 2294
+ +N KNRYK++LPYD TRV L YINAS++ + + V YIA QGPLP T
Sbjct: 378 AKLPQNLDKNRYKDVLPYDTTRVLLQGNEDYINASYVNMEIPAANLVNKYIATQGPLPHT 437
Query: 2295 VGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSNRLRLALVRMQQLKG 2354
FWQ++W+QK ++I M+T E + KC +YWP+ M +
Sbjct: 438 CAQFWQVVWDQKLSLIVMLTTLTERGRTKCHQYWPD--PPDVMNHGGFHIQCQSEDCTIA 495
Query: 2355 FVVRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYMRHIH-RSGPIITHC 2413
+V R M + + QT E ++HL + AWPDH P D L F++Y+R + S P++ HC
Sbjct: 496 YVSREMLVTNTQTGEEHTVTHLQYVAWPDHGVPDDSSDFLEFVNYVRSLRVDSEPVLVHC 555
Query: 2414 SAGIGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTEDQYIFCYQVILYV 2472
SAGIGR+G L+ ++ + L ++L D+VR MR QR MVQT QY F + IL V
Sbjct: 556 SAGIGRTGVLVTMETAMCLTERNLPIYPLDIVRKMRDQRAMMVQTSSQYKFVCEAILRV 614
Score = 38.9 bits (89), Expect = 0.064
Identities = 58/269 (21%), Positives = 108/269 (40%), Gaps = 30/269 (11%)
Query: 1611 SPAQVLPNSSKDSSQPSCVEQSTSSDENEMSDKSKKQCKSPSRRDSYSDSSGSGEDDLVT 1670
+PA S + S +S N S + + + + P R S +D+ + E +T
Sbjct: 64 NPAMRRSLSVEHLETKSLPSRSPPITPNWRSPRLRHEIRKP--RHSSADNLAN-EMTYIT 120
Query: 1671 APANISNSTWSSALHQTLSNMVSQAQSHHEAPKSQEDTICTMFYYPQKIPNKPEFEDSNP 1730
++ + S Q + VSQ +S H+ S+ + Y QK S+
Sbjct: 121 ETEDVFYTYKGSLAPQDSDSEVSQNRSPHQESLSENNP--AQSYLTQK---------SSS 169
Query: 1731 SPLPPDMAPGQSYQPQSESASSSSMDKYHIHHISEPTRQENWTPLKNDLENHLEDFELEV 1790
S P APG + +D +H +++ E+ + D ++ + + +
Sbjct: 170 SVSPSSNAPGSC---SPDGVDQQLLDDFH--RVTKGGSTEDASQYYCDKNDNGDSYLV-- 222
Query: 1791 ELLITLIKSEKGSLGFTVTKGNQRIGCYVHDVIQDPAKSDG---RLKPGDRLIKVNDTDV 1847
LI + E G GF + G + V I + +D +L GD+++ +N D+
Sbjct: 223 --LIRITPDEDGKFGFNLKGGVDQKMPLVVSRINPESPADTCIPKLNEGDQIVLINGRDI 280
Query: 1848 TNMTHTDAVNLLRAA----SKTVRLVIGR 1872
+ TH V ++A+ S+ + LVI R
Sbjct: 281 SEHTHDQVVMFIKASRESHSRELALVIRR 309
>gi|223941885 protein tyrosine phosphatase, non-receptor type 3
isoform 4 [Homo sapiens]
Length = 737
Score = 190 bits (482), Expect = 2e-47
Identities = 110/299 (36%), Positives = 156/299 (52%), Gaps = 5/299 (1%)
Query: 2177 FLTNDELAVLPVVKVLPSGKYTGANLKSVIRVLRGLLDQGIPSKELENLQELKPLDQCLI 2236
F + DEL L + P G L+ + L+ L+ G + E L KP
Sbjct: 429 FKSEDELNQLFPEAIFPMCPEGGDTLEGSMAQLKKGLESGTVLIQFEQLYRKKPGLAITF 488
Query: 2237 GQTKENRRKNRYKNILPYDATRVPLGDEGGYINASFIKIPVGKEEFV--YIACQGPLPTT 2294
+ +N KNRYK++LPYD TRV L YINAS++ + + V YIA QGPLP T
Sbjct: 489 AKLPQNLDKNRYKDVLPYDTTRVLLQGNEDYINASYVNMEIPAANLVNKYIATQGPLPHT 548
Query: 2295 VGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSNRLRLALVRMQQLKG 2354
FWQ++W+QK ++I M+T E + KC +YWP+ M +
Sbjct: 549 CAQFWQVVWDQKLSLIVMLTTLTERGRTKCHQYWPD--PPDVMNHGGFHIQCQSEDCTIA 606
Query: 2355 FVVRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYMRHIH-RSGPIITHC 2413
+V R M + + QT E ++HL + AWPDH P D L F++Y+R + S P++ HC
Sbjct: 607 YVSREMLVTNTQTGEEHTVTHLQYVAWPDHGVPDDSSDFLEFVNYVRSLRVDSEPVLVHC 666
Query: 2414 SAGIGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTEDQYIFCYQVILYV 2472
SAGIGR+G L+ ++ + L ++L D+VR MR QR MVQT QY F + IL V
Sbjct: 667 SAGIGRTGVLVTMETAMCLTERNLPIYPLDIVRKMRDQRAMMVQTSSQYKFVCEAILRV 725
Score = 76.3 bits (186), Expect = 4e-13
Identities = 99/492 (20%), Positives = 184/492 (37%), Gaps = 93/492 (18%)
Query: 686 DILEERMHCDDETSLLLASLALQAEYGDYQPEVHGVSYFRMEHYLPARVMEKLDLSYIKE 745
DI E R+ C ++++LAS A+Q+ +GDY +H Y H++P + + L
Sbjct: 2 DICEGRLTCPLNSAVVLASYAVQSHFGDYNSSIHHPGYLSDSHFIPDQNEDFL------T 55
Query: 746 ELPKLHNTYVGASEKETELEFLKVCQRLTEYGVHFHRVHPEKKSQTGILLGVCSKGVLVF 805
++ LH + G + E E ++ + + L YGV H +++G+ S GV V+
Sbjct: 56 KVESLHEQHSGLKQSEAESCYINIARTLDFYGVELH--SGRDLHNLDLMIGIASAGVAVY 113
Query: 806 EVHNGVRTLVLRFPWRETKKISFSKKKITL---QNTSDGIKH--GFQTDNSKICQYLLHL 860
+ +PW KISF +KK + Q ++ +H F N + C+ L
Sbjct: 114 RKY----ICTSFYPWVNILKISFKRKKFFIHQRQKQAESREHIVAFNMLNYRSCKNLWKS 169
Query: 861 CSYQHKFQLQMRARQSNQDAQDIERASFRSLNLQAESVRGFNMGRAISTGSLASSTLNKL 920
C H F QA+ + ++ S K
Sbjct: 170 CVEHHTF-------------------------FQAKKLLPQEKNVLSQYWTMGSRNTKKR 204
Query: 921 AVRPLSVQAEILKRLSCSELSLYQPLQNSSKEKNDKASWEEKPREMSKSYHDLSQASLYP 980
+ R ++ EI K P +S+ ++ ++ + ++ +Y + SL P
Sbjct: 205 SPR---LRHEIRK-----------PRHSSADNLANEMTYITETEDVFYTY----KGSLAP 246
Query: 981 HRKNVIVNMEPPPQTVAELVGKPSHQMSRSDAESLAGVTKLNNSKSVASLNRSPERRKHE 1040
+ V+ P HQ S S+ +S SV+ + +P +
Sbjct: 247 QDSDSEVSQNRSP-----------HQESLSENNPAQSYLTQKSSSSVSPSSNAPGSCSPD 295
Query: 1041 SDSSSIEDPGQAYVLGMTMHSSGNSSSQVPLKENDVLHKRWSIVSSPEREITLVNLKKDA 1100
+ D +T S +SQ +ND + + + L+ + D
Sbjct: 296 GVDQQLLDDFHR----VTKGGSTEDASQYYCDKND----------NGDSYLVLIRITPDE 341
Query: 1101 KYGLGFQIIGGEKMGRLDLGIFISSVAPGGPADLDGC---LKPGDRLISVNSVSLEGVSH 1157
GF + GG + + +S + P PAD C L GD+++ +N + +H
Sbjct: 342 DGKFGFNLKGGVDQ---KMPLVVSRINPESPADT--CIPKLNEGDQIVLINGRDISEHTH 396
Query: 1158 HAAIEILQNAPE 1169
+ ++ + E
Sbjct: 397 DQVVMFIKASRE 408
Score = 39.7 bits (91), Expect = 0.037
Identities = 56/256 (21%), Positives = 103/256 (40%), Gaps = 34/256 (13%)
Query: 1630 EQSTSSDENEMSDKSKKQCKSPSRRDSYSDSSGSGEDDL------VTAPANISNSTWSSA 1683
E++ S M ++ K+ +SP R S D+L +T ++ + S
Sbjct: 186 EKNVLSQYWTMGSRNTKK-RSPRLRHEIRKPRHSSADNLANEMTYITETEDVFYTYKGSL 244
Query: 1684 LHQTLSNMVSQAQSHHEAPKSQEDTICTMFYYPQKIPNKPEFEDSNPSPLPPDMAPGQSY 1743
Q + VSQ +S H+ S+ + Y QK S+ S P APG
Sbjct: 245 APQDSDSEVSQNRSPHQESLSENNP--AQSYLTQK---------SSSSVSPSSNAPGSC- 292
Query: 1744 QPQSESASSSSMDKYHIHHISEPTRQENWTPLKNDLENHLEDFELEVELLITLIKSEKGS 1803
+ +D +H +++ E+ + D ++ + + + LI + E G
Sbjct: 293 --SPDGVDQQLLDDFH--RVTKGGSTEDASQYYCDKNDNGDSYLV----LIRITPDEDGK 344
Query: 1804 LGFTVTKGNQRIGCYVHDVIQDPAKSDG---RLKPGDRLIKVNDTDVTNMTHTDAVNLLR 1860
GF + G + V I + +D +L GD+++ +N D++ TH V ++
Sbjct: 345 FGFNLKGGVDQKMPLVVSRINPESPADTCIPKLNEGDQIVLINGRDISEHTHDQVVMFIK 404
Query: 1861 AA----SKTVRLVIGR 1872
A+ S+ + LVI R
Sbjct: 405 ASRESHSRELALVIRR 420
>gi|223941882 protein tyrosine phosphatase, non-receptor type 3
isoform 3 [Homo sapiens]
Length = 782
Score = 190 bits (482), Expect = 2e-47
Identities = 110/299 (36%), Positives = 156/299 (52%), Gaps = 5/299 (1%)
Query: 2177 FLTNDELAVLPVVKVLPSGKYTGANLKSVIRVLRGLLDQGIPSKELENLQELKPLDQCLI 2236
F + DEL L + P G L+ + L+ L+ G + E L KP
Sbjct: 474 FKSEDELNQLFPEAIFPMCPEGGDTLEGSMAQLKKGLESGTVLIQFEQLYRKKPGLAITF 533
Query: 2237 GQTKENRRKNRYKNILPYDATRVPLGDEGGYINASFIKIPVGKEEFV--YIACQGPLPTT 2294
+ +N KNRYK++LPYD TRV L YINAS++ + + V YIA QGPLP T
Sbjct: 534 AKLPQNLDKNRYKDVLPYDTTRVLLQGNEDYINASYVNMEIPAANLVNKYIATQGPLPHT 593
Query: 2295 VGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSNRLRLALVRMQQLKG 2354
FWQ++W+QK ++I M+T E + KC +YWP+ M +
Sbjct: 594 CAQFWQVVWDQKLSLIVMLTTLTERGRTKCHQYWPD--PPDVMNHGGFHIQCQSEDCTIA 651
Query: 2355 FVVRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYMRHIH-RSGPIITHC 2413
+V R M + + QT E ++HL + AWPDH P D L F++Y+R + S P++ HC
Sbjct: 652 YVSREMLVTNTQTGEEHTVTHLQYVAWPDHGVPDDSSDFLEFVNYVRSLRVDSEPVLVHC 711
Query: 2414 SAGIGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTEDQYIFCYQVILYV 2472
SAGIGR+G L+ ++ + L ++L D+VR MR QR MVQT QY F + IL V
Sbjct: 712 SAGIGRTGVLVTMETAMCLTERNLPIYPLDIVRKMRDQRAMMVQTSSQYKFVCEAILRV 770
Score = 82.4 bits (202), Expect = 5e-15
Identities = 103/501 (20%), Positives = 197/501 (39%), Gaps = 66/501 (13%)
Query: 686 DILEERMHCDDETSLLLASLALQAEYGDYQPEVHGVSYFRMEHYLPARVMEKLDLSYIKE 745
DI E R+ C ++++LAS A+Q+ +GDY +H Y H++P + + L
Sbjct: 2 DICEGRLTCPLNSAVVLASYAVQSHFGDYNSSIHHPGYLSDSHFIPDQNEDFL------T 55
Query: 746 ELPKLHNTYVGASEKETELEFLKVCQRLTEYGVHFHRVHPEKKSQTGILLGVCSKGVLVF 805
++ LH + G + E E ++ + + L YGV H +++G+ S GV V+
Sbjct: 56 KVESLHEQHSGLKQSEAESCYINIARTLDFYGVELH--SGRDLHNLDLMIGIASAGVAVY 113
Query: 806 EVHNGVRTLVLRFPWRETKKISFSKKKITL---QNTSDGIKH--GFQTDNSKICQYLLHL 860
+ +PW KISF +KK + Q ++ +H F N + C+ L
Sbjct: 114 RKY----ICTSFYPWVNILKISFKRKKFFIHQRQKQAESREHIVAFNMLNYRSCKNLWKS 169
Query: 861 CSYQHKFQLQMRARQSNQDAQDI--------ERASFRSLNLQ-AESVRGFNMGRAISTGS 911
C H F +A++ +++ R + +S+N Q + V G + S
Sbjct: 170 CVEHHTF---FQAKKLLPQEKNVLSQYWTMGSRNTKKSVNNQYCKKVIGGMVWNPAMRRS 226
Query: 912 LASSTLNKLAVRPLSVQAEILKRLSCSELSLYQPLQNSSKEKNDKASWEEKPREMSKSYH 971
L+ L ++ S R + +P +S+ ++ ++ + ++ +Y
Sbjct: 227 LSVEHLETKSLPSRSPPITPNWRSPRLRHEIRKPRHSSADNLANEMTYITETEDVFYTY- 285
Query: 972 DLSQASLYPHRKNVIVNMEPPPQTVAELVGKPSHQMSRSDAESLAGVTKLNNSKSVASLN 1031
+ SL P + V+ P HQ S S+ +S SV+ +
Sbjct: 286 ---KGSLAPQDSDSEVSQNRSP-----------HQESLSENNPAQSYLTQKSSSSVSPSS 331
Query: 1032 RSPERRKHESDSSSIEDPGQAYVLGMTMHSSGNSSSQVPLKENDVLHKRWSIVSSPEREI 1091
+P + + D +T S +SQ +ND + + +
Sbjct: 332 NAPGSCSPDGVDQQLLDDFHR----VTKGGSTEDASQYYCDKND----------NGDSYL 377
Query: 1092 TLVNLKKDAKYGLGFQIIGGEKMGRLDLGIFISSVAPGGPADLDGC---LKPGDRLISVN 1148
L+ + D GF + GG + + +S + P PAD C L GD+++ +N
Sbjct: 378 VLIRITPDEDGKFGFNLKGGVDQ---KMPLVVSRINPESPADT--CIPKLNEGDQIVLIN 432
Query: 1149 SVSLEGVSHHAAIEILQNAPE 1169
+ +H + ++ + E
Sbjct: 433 GRDISEHTHDQVVMFIKASRE 453
Score = 38.9 bits (89), Expect = 0.064
Identities = 58/269 (21%), Positives = 108/269 (40%), Gaps = 30/269 (11%)
Query: 1611 SPAQVLPNSSKDSSQPSCVEQSTSSDENEMSDKSKKQCKSPSRRDSYSDSSGSGEDDLVT 1670
+PA S + S +S N S + + + + P R S +D+ + E +T
Sbjct: 220 NPAMRRSLSVEHLETKSLPSRSPPITPNWRSPRLRHEIRKP--RHSSADNLAN-EMTYIT 276
Query: 1671 APANISNSTWSSALHQTLSNMVSQAQSHHEAPKSQEDTICTMFYYPQKIPNKPEFEDSNP 1730
++ + S Q + VSQ +S H+ S+ + Y QK S+
Sbjct: 277 ETEDVFYTYKGSLAPQDSDSEVSQNRSPHQESLSENNP--AQSYLTQK---------SSS 325
Query: 1731 SPLPPDMAPGQSYQPQSESASSSSMDKYHIHHISEPTRQENWTPLKNDLENHLEDFELEV 1790
S P APG + +D +H +++ E+ + D ++ + + +
Sbjct: 326 SVSPSSNAPGSC---SPDGVDQQLLDDFH--RVTKGGSTEDASQYYCDKNDNGDSYLV-- 378
Query: 1791 ELLITLIKSEKGSLGFTVTKGNQRIGCYVHDVIQDPAKSDG---RLKPGDRLIKVNDTDV 1847
LI + E G GF + G + V I + +D +L GD+++ +N D+
Sbjct: 379 --LIRITPDEDGKFGFNLKGGVDQKMPLVVSRINPESPADTCIPKLNEGDQIVLINGRDI 436
Query: 1848 TNMTHTDAVNLLRAA----SKTVRLVIGR 1872
+ TH V ++A+ S+ + LVI R
Sbjct: 437 SEHTHDQVVMFIKASRESHSRELALVIRR 465
>gi|223941879 protein tyrosine phosphatase, non-receptor type 3
isoform 2 [Homo sapiens]
Length = 868
Score = 190 bits (482), Expect = 2e-47
Identities = 110/299 (36%), Positives = 156/299 (52%), Gaps = 5/299 (1%)
Query: 2177 FLTNDELAVLPVVKVLPSGKYTGANLKSVIRVLRGLLDQGIPSKELENLQELKPLDQCLI 2236
F + DEL L + P G L+ + L+ L+ G + E L KP
Sbjct: 560 FKSEDELNQLFPEAIFPMCPEGGDTLEGSMAQLKKGLESGTVLIQFEQLYRKKPGLAITF 619
Query: 2237 GQTKENRRKNRYKNILPYDATRVPLGDEGGYINASFIKIPVGKEEFV--YIACQGPLPTT 2294
+ +N KNRYK++LPYD TRV L YINAS++ + + V YIA QGPLP T
Sbjct: 620 AKLPQNLDKNRYKDVLPYDTTRVLLQGNEDYINASYVNMEIPAANLVNKYIATQGPLPHT 679
Query: 2295 VGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSNRLRLALVRMQQLKG 2354
FWQ++W+QK ++I M+T E + KC +YWP+ M +
Sbjct: 680 CAQFWQVVWDQKLSLIVMLTTLTERGRTKCHQYWPD--PPDVMNHGGFHIQCQSEDCTIA 737
Query: 2355 FVVRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYMRHIH-RSGPIITHC 2413
+V R M + + QT E ++HL + AWPDH P D L F++Y+R + S P++ HC
Sbjct: 738 YVSREMLVTNTQTGEEHTVTHLQYVAWPDHGVPDDSSDFLEFVNYVRSLRVDSEPVLVHC 797
Query: 2414 SAGIGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTEDQYIFCYQVILYV 2472
SAGIGR+G L+ ++ + L ++L D+VR MR QR MVQT QY F + IL V
Sbjct: 798 SAGIGRTGVLVTMETAMCLTERNLPIYPLDIVRKMRDQRAMMVQTSSQYKFVCEAILRV 856
Score = 113 bits (282), Expect = 3e-24
Identities = 128/584 (21%), Positives = 225/584 (38%), Gaps = 109/584 (18%)
Query: 597 VFDMVVAHIGLVEHHLFALATLKDNEYFFVDPDLKLTKVAPEGWKEEPK---KKTKATVN 653
+ DMV H+G+ E F L D+ V W E K K+ K
Sbjct: 54 LLDMVHNHLGVTEKEYFGLQHDDDS-------------VDSPRWLEASKAIRKQLKGGFP 100
Query: 654 FTLFFRIKFFMDDVSLIQHTLTCHQYYLQLRKDILEERMHCDDETSLLLASLALQAEYGD 713
TL FR++FF+ D + +Q T H Y+LQL+ DI E R+ C ++++LAS A+Q+ +GD
Sbjct: 101 CTLHFRVRFFIPDPNTLQQEQTRHLYFLQLKMDICEGRLTCPLNSAVVLASYAVQSHFGD 160
Query: 714 YQPEVHGVSYFRMEHYLPARVMEKLDLSYIKEELPKLHNTYVGASEKETELEFLKVCQRL 773
Y +H Y H++P + + L ++ LH + G + E E ++ + + L
Sbjct: 161 YNSSIHHPGYLSDSHFIPDQNEDFL------TKVESLHEQHSGLKQSEAESCYINIARTL 214
Query: 774 TEYGVHFHRVHPEKKSQTGILLGVCSKGVLVFEVHNGVRTLVLRFPWRETKKISFSKKKI 833
YGV H +++G+ S GV V+ + +PW KISF +KK
Sbjct: 215 DFYGVELH--SGRDLHNLDLMIGIASAGVAVYRKY----ICTSFYPWVNILKISFKRKKF 268
Query: 834 TL---QNTSDGIKH--GFQTDNSKICQYLLHLCSYQHKFQLQMRARQSNQDAQDIERASF 888
+ Q ++ +H F N + C+ L C H F
Sbjct: 269 FIHQRQKQAESREHIVAFNMLNYRSCKNLWKSCVEHHTF--------------------- 307
Query: 889 RSLNLQAESVRGFNMGRAISTGSLASSTLNKLAVRPLSVQAEILKRLSCSELSLYQPLQN 948
QA+ + ++ S K + R ++ EI K P +
Sbjct: 308 ----FQAKKLLPQEKNVLSQYWTMGSRNTKKRSPR---LRHEIRK-----------PRHS 349
Query: 949 SSKEKNDKASWEEKPREMSKSYHDLSQASLYPHRKNVIVNMEPPPQTVAELVGKPSHQMS 1008
S+ ++ ++ + ++ +Y + SL P + V+ P HQ S
Sbjct: 350 SADNLANEMTYITETEDVFYTY----KGSLAPQDSDSEVSQNRSP-----------HQES 394
Query: 1009 RSDAESLAGVTKLNNSKSVASLNRSPERRKHESDSSSIEDPGQAYVLGMTMHSSGNSSSQ 1068
S+ +S SV+ + +P + + D +T S +SQ
Sbjct: 395 LSENNPAQSYLTQKSSSSVSPSSNAPGSCSPDGVDQQLLDDFHR----VTKGGSTEDASQ 450
Query: 1069 VPLKENDVLHKRWSIVSSPEREITLVNLKKDAKYGLGFQIIGGEKMGRLDLGIFISSVAP 1128
+ND + + + L+ + D GF + GG + + +S + P
Sbjct: 451 YYCDKND----------NGDSYLVLIRITPDEDGKFGFNLKGGVDQ---KMPLVVSRINP 497
Query: 1129 GGPADLDGC---LKPGDRLISVNSVSLEGVSHHAAIEILQNAPE 1169
PAD C L GD+++ +N + +H + ++ + E
Sbjct: 498 ESPADT--CIPKLNEGDQIVLINGRDISEHTHDQVVMFIKASRE 539
Score = 39.7 bits (91), Expect = 0.037
Identities = 56/256 (21%), Positives = 103/256 (40%), Gaps = 34/256 (13%)
Query: 1630 EQSTSSDENEMSDKSKKQCKSPSRRDSYSDSSGSGEDDL------VTAPANISNSTWSSA 1683
E++ S M ++ K+ +SP R S D+L +T ++ + S
Sbjct: 317 EKNVLSQYWTMGSRNTKK-RSPRLRHEIRKPRHSSADNLANEMTYITETEDVFYTYKGSL 375
Query: 1684 LHQTLSNMVSQAQSHHEAPKSQEDTICTMFYYPQKIPNKPEFEDSNPSPLPPDMAPGQSY 1743
Q + VSQ +S H+ S+ + Y QK S+ S P APG
Sbjct: 376 APQDSDSEVSQNRSPHQESLSENNP--AQSYLTQK---------SSSSVSPSSNAPGSC- 423
Query: 1744 QPQSESASSSSMDKYHIHHISEPTRQENWTPLKNDLENHLEDFELEVELLITLIKSEKGS 1803
+ +D +H +++ E+ + D ++ + + + LI + E G
Sbjct: 424 --SPDGVDQQLLDDFH--RVTKGGSTEDASQYYCDKNDNGDSYLV----LIRITPDEDGK 475
Query: 1804 LGFTVTKGNQRIGCYVHDVIQDPAKSDG---RLKPGDRLIKVNDTDVTNMTHTDAVNLLR 1860
GF + G + V I + +D +L GD+++ +N D++ TH V ++
Sbjct: 476 FGFNLKGGVDQKMPLVVSRINPESPADTCIPKLNEGDQIVLINGRDISEHTHDQVVMFIK 535
Query: 1861 AA----SKTVRLVIGR 1872
A+ S+ + LVI R
Sbjct: 536 ASRESHSRELALVIRR 551
>gi|223941876 protein tyrosine phosphatase, non-receptor type 3
isoform 1 [Homo sapiens]
Length = 913
Score = 190 bits (482), Expect = 2e-47
Identities = 110/299 (36%), Positives = 156/299 (52%), Gaps = 5/299 (1%)
Query: 2177 FLTNDELAVLPVVKVLPSGKYTGANLKSVIRVLRGLLDQGIPSKELENLQELKPLDQCLI 2236
F + DEL L + P G L+ + L+ L+ G + E L KP
Sbjct: 605 FKSEDELNQLFPEAIFPMCPEGGDTLEGSMAQLKKGLESGTVLIQFEQLYRKKPGLAITF 664
Query: 2237 GQTKENRRKNRYKNILPYDATRVPLGDEGGYINASFIKIPVGKEEFV--YIACQGPLPTT 2294
+ +N KNRYK++LPYD TRV L YINAS++ + + V YIA QGPLP T
Sbjct: 665 AKLPQNLDKNRYKDVLPYDTTRVLLQGNEDYINASYVNMEIPAANLVNKYIATQGPLPHT 724
Query: 2295 VGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSNRLRLALVRMQQLKG 2354
FWQ++W+QK ++I M+T E + KC +YWP+ M +
Sbjct: 725 CAQFWQVVWDQKLSLIVMLTTLTERGRTKCHQYWPD--PPDVMNHGGFHIQCQSEDCTIA 782
Query: 2355 FVVRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYMRHIH-RSGPIITHC 2413
+V R M + + QT E ++HL + AWPDH P D L F++Y+R + S P++ HC
Sbjct: 783 YVSREMLVTNTQTGEEHTVTHLQYVAWPDHGVPDDSSDFLEFVNYVRSLRVDSEPVLVHC 842
Query: 2414 SAGIGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTEDQYIFCYQVILYV 2472
SAGIGR+G L+ ++ + L ++L D+VR MR QR MVQT QY F + IL V
Sbjct: 843 SAGIGRTGVLVTMETAMCLTERNLPIYPLDIVRKMRDQRAMMVQTSSQYKFVCEAILRV 901
Score = 119 bits (298), Expect = 4e-26
Identities = 132/593 (22%), Positives = 238/593 (40%), Gaps = 82/593 (13%)
Query: 597 VFDMVVAHIGLVEHHLFALATLKDNEYFFVDPDLKLTKVAPEGWKEEPK---KKTKATVN 653
+ DMV H+G+ E F L D+ V W E K K+ K
Sbjct: 54 LLDMVHNHLGVTEKEYFGLQHDDDS-------------VDSPRWLEASKAIRKQLKGGFP 100
Query: 654 FTLFFRIKFFMDDVSLIQHTLTCHQYYLQLRKDILEERMHCDDETSLLLASLALQAEYGD 713
TL FR++FF+ D + +Q T H Y+LQL+ DI E R+ C ++++LAS A+Q+ +GD
Sbjct: 101 CTLHFRVRFFIPDPNTLQQEQTRHLYFLQLKMDICEGRLTCPLNSAVVLASYAVQSHFGD 160
Query: 714 YQPEVHGVSYFRMEHYLPARVMEKLDLSYIKEELPKLHNTYVGASEKETELEFLKVCQRL 773
Y +H Y H++P + + L ++ LH + G + E E ++ + + L
Sbjct: 161 YNSSIHHPGYLSDSHFIPDQNEDFL------TKVESLHEQHSGLKQSEAESCYINIARTL 214
Query: 774 TEYGVHFHRVHPEKKSQTGILLGVCSKGVLVFEVHNGVRTLVLRFPWRETKKISFSKKKI 833
YGV H +++G+ S GV V+ + +PW KISF +KK
Sbjct: 215 DFYGVELH--SGRDLHNLDLMIGIASAGVAVYRKY----ICTSFYPWVNILKISFKRKKF 268
Query: 834 TL---QNTSDGIKH--GFQTDNSKICQYLLHLCSYQHKFQLQMRARQSNQDAQDI----- 883
+ Q ++ +H F N + C+ L C H F +A++ +++
Sbjct: 269 FIHQRQKQAESREHIVAFNMLNYRSCKNLWKSCVEHHTF---FQAKKLLPQEKNVLSQYW 325
Query: 884 ---ERASFRSLNLQ-AESVRGFNMGRAISTGSLASSTLNKLAVRPLSVQAEILKRLSCSE 939
R + +S+N Q + V G + SL+ L ++ S R
Sbjct: 326 TMGSRNTKKSVNNQYCKKVIGGMVWNPAMRRSLSVEHLETKSLPSRSPPITPNWRSPRLR 385
Query: 940 LSLYQPLQNSSKEKNDKASWEEKPREMSKSYHDLSQASLYPHRKNVIVNMEPPPQTVAEL 999
+ +P +S+ ++ ++ + ++ +Y + SL P + V+ P
Sbjct: 386 HEIRKPRHSSADNLANEMTYITETEDVFYTY----KGSLAPQDSDSEVSQNRSP------ 435
Query: 1000 VGKPSHQMSRSDAESLAGVTKLNNSKSVASLNRSPERRKHESDSSSIEDPGQAYVLGMTM 1059
HQ S S+ +S SV+ + +P + + D +T
Sbjct: 436 -----HQESLSENNPAQSYLTQKSSSSVSPSSNAPGSCSPDGVDQQLLDDFHR----VTK 486
Query: 1060 HSSGNSSSQVPLKENDVLHKRWSIVSSPEREITLVNLKKDAKYGLGFQIIGGEKMGRLDL 1119
S +SQ +ND + + + L+ + D GF + GG +
Sbjct: 487 GGSTEDASQYYCDKND----------NGDSYLVLIRITPDEDGKFGFNLKGGVDQ---KM 533
Query: 1120 GIFISSVAPGGPADLDGC---LKPGDRLISVNSVSLEGVSHHAAIEILQNAPE 1169
+ +S + P PAD C L GD+++ +N + +H + ++ + E
Sbjct: 534 PLVVSRINPESPADT--CIPKLNEGDQIVLINGRDISEHTHDQVVMFIKASRE 584
Score = 38.9 bits (89), Expect = 0.064
Identities = 58/269 (21%), Positives = 108/269 (40%), Gaps = 30/269 (11%)
Query: 1611 SPAQVLPNSSKDSSQPSCVEQSTSSDENEMSDKSKKQCKSPSRRDSYSDSSGSGEDDLVT 1670
+PA S + S +S N S + + + + P R S +D+ + E +T
Sbjct: 351 NPAMRRSLSVEHLETKSLPSRSPPITPNWRSPRLRHEIRKP--RHSSADNLAN-EMTYIT 407
Query: 1671 APANISNSTWSSALHQTLSNMVSQAQSHHEAPKSQEDTICTMFYYPQKIPNKPEFEDSNP 1730
++ + S Q + VSQ +S H+ S+ + Y QK S+
Sbjct: 408 ETEDVFYTYKGSLAPQDSDSEVSQNRSPHQESLSENNP--AQSYLTQK---------SSS 456
Query: 1731 SPLPPDMAPGQSYQPQSESASSSSMDKYHIHHISEPTRQENWTPLKNDLENHLEDFELEV 1790
S P APG + +D +H +++ E+ + D ++ + + +
Sbjct: 457 SVSPSSNAPGSC---SPDGVDQQLLDDFH--RVTKGGSTEDASQYYCDKNDNGDSYLV-- 509
Query: 1791 ELLITLIKSEKGSLGFTVTKGNQRIGCYVHDVIQDPAKSDG---RLKPGDRLIKVNDTDV 1847
LI + E G GF + G + V I + +D +L GD+++ +N D+
Sbjct: 510 --LIRITPDEDGKFGFNLKGGVDQKMPLVVSRINPESPADTCIPKLNEGDQIVLINGRDI 567
Query: 1848 TNMTHTDAVNLLRAA----SKTVRLVIGR 1872
+ TH V ++A+ S+ + LVI R
Sbjct: 568 SEHTHDQVVMFIKASRESHSRELALVIRR 596
>gi|33356177 protein tyrosine phosphatase, non-receptor type 11 [Homo
sapiens]
Length = 593
Score = 189 bits (480), Expect = 3e-47
Identities = 125/330 (37%), Positives = 175/330 (53%), Gaps = 31/330 (9%)
Query: 2185 VLPVVKVLPSGKYTGANLKSVIRVLRGLLDQGIPSK-----ELENLQ--ELKPLDQCLIG 2237
VL + + L + + A ++S +R L L + K E E LQ E K L G
Sbjct: 209 VLQLKQPLNTTRINAAEIESRVRELSKLAETTDKVKQGFWEEFETLQQQECKLLYSRKEG 268
Query: 2238 QTKENRRKNRYKNILPYDATRVPLGDE------GGYINASFI------KIPVGKEEFVYI 2285
Q +EN+ KNRYKNILP+D TRV L D YINA+ I K K + YI
Sbjct: 269 QRQENKNKNRYKNILPFDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYI 328
Query: 2286 ACQGPLPTTVGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSNRLRLA 2345
A QG L TV DFW+M++++ S VI M T+EVE K KC +YWP+ +R+
Sbjct: 329 ATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEY--GVMRVR 386
Query: 2346 LVRMQQLKGFVVRAMTLEDI-QTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYMRH-- 2402
V+ + +R + L + Q R + +F WPDH PS P +L F+ + H
Sbjct: 387 NVKESAAHDYTLRELKLSKVGQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQ 446
Query: 2403 --IHRSGPIITHCSAGIGRSGTLICIDVVLGLISQ---DLDFDISDLVRCMRLQRHGMVQ 2457
I +GP++ HCSAGIGR+GT I ID+++ +I + D D D+ ++ +R QR GMVQ
Sbjct: 447 ESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQ 506
Query: 2458 TEDQYIFCYQVILYVLTRLQ--AEEEQKQQ 2485
TE QY F Y + + + LQ EEEQK +
Sbjct: 507 TEAQYRFIYMAVQHYIETLQRRIEEEQKSK 536
>gi|4506295 protein tyrosine phosphatase, non-receptor type 4 [Homo
sapiens]
Length = 926
Score = 186 bits (473), Expect = 2e-46
Identities = 104/275 (37%), Positives = 156/275 (56%), Gaps = 9/275 (3%)
Query: 2203 KSVIRVLRGLLDQGIPSKELENLQELKPLDQCLIGQTKENRRKNRYKNILPYDATRVPLG 2262
+S+I++ GL+ G + + L KP + +N KNRY++I PYDATRV L
Sbjct: 641 ESMIQLAEGLIT-GTVLTQFDQLYRKKPGMTMSCAKLPQNISKNRYRDISPYDATRVILK 699
Query: 2263 DEGGYINASFIKIPVGKEEFV--YIACQGPLPTTVGDFWQMIWEQKSTVIAMMTQEVEGE 2320
YINA++I + + + YIACQGPLP T DFWQM WEQ S+++ M+T +VE
Sbjct: 700 GNEDYINANYINMEIPSSSIINQYIACQGPLPHTCTDFWQMTWEQGSSMVVMLTTQVERG 759
Query: 2321 KIKCQRYWPNILGKTTMVSNRLRLALVRMQQLKGFVVRAMTLEDIQTREVRHISHLNFTA 2380
++KC +YWP G ++ ++ + ++ R MTL + + E R ++ + + A
Sbjct: 760 RVKCHQYWPEPTGSSSY--GCYQVTCHSEEGNTAYIFRKMTLFNQEKNESRPLTQIQYIA 817
Query: 2381 WPDHDTPSQPDDLLTFISYMRHIHRSG---PIITHCSAGIGRSGTLICIDVVLGLISQDL 2437
WPDH P D L F+ ++R+ R+G P++ HCSAGIGR+G LI ++ + LI +
Sbjct: 818 WPDHGVPDDSSDFLDFVCHVRN-KRAGKEEPVVVHCSAGIGRTGVLITMETAMCLIECNQ 876
Query: 2438 DFDISDLVRCMRLQRHGMVQTEDQYIFCYQVILYV 2472
D+VR MR QR M+QT QY F + IL V
Sbjct: 877 PVYPLDIVRTMRDQRAMMIQTPSQYRFVCEAILKV 911
Score = 145 bits (365), Expect = 6e-34
Identities = 172/683 (25%), Positives = 285/683 (41%), Gaps = 93/683 (13%)
Query: 575 NIMLLNGQRLELTCDTKTICKDVFDMVVAHIGLVEHHLFALATLKDN--EYFFVDPDLKL 632
NI+LL+ + + + D+V H+ L E F L D+ ++DP+ +
Sbjct: 32 NILLLDNTVQAFKVNKHDQGQVLLDVVFKHLDLTEQDYFGLQLADDSTDNPRWLDPNKPI 91
Query: 633 TKVAPEGWKEEPKKKTKATVNFTLFFRIKFFMDDVSLIQHTLTCHQYYLQLRKDILEERM 692
+K+ K ++L FR+KFF+ D + +Q T +QY+LQ+++DIL R+
Sbjct: 92 ------------RKQLKRGSPYSLNFRVKFFVSDPNKLQEEYTRYQYFLQIKQDILTGRL 139
Query: 693 HCDDETSLLLASLALQAEYGDYQPEVHGVSYFRMEHYLPARVMEKLDLSYIKEELPKLHN 752
C T+ LLAS A+Q+E GDY + Y ++P + + ++E+ KLH
Sbjct: 140 PCPSNTAALLASFAVQSELGDYDQSENLSGYLSDYSFIPNQPQD------FEKEIAKLHQ 193
Query: 753 TYVGASEKETELEFLKVCQRLTEYGVHFHRVHPEKKSQTGILLGVCSKGVLVFEVHNGVR 812
++G S E E +L + L YGV FH + +S I++GV S G+L+++ N VR
Sbjct: 194 QHIGLSPAEAEFNYLNTARTLELYGVEFH--YARDQSNNEIMIGVMSGGILIYK--NRVR 249
Query: 813 TLVLRFPWRETKKISFSKKKITLQ-----NTSDGIKHGFQTDNSKICQYLLHLCSYQHKF 867
+ FPW + KISF K+ +Q + S GF N + C+ L C H F
Sbjct: 250 --MNTFPWLKIVKISFKCKQFFIQLRKELHESRETLLGFNMVNYRACKNLWKACVEHHTF 307
Query: 868 QLQMR--ARQSNQDAQDIERAS-FRSL-NLQAESVRGFNMGRAISTGSLASSTLNKLAVR 923
R Q N A S FR + +SV+ + +A A S LA +
Sbjct: 308 FRLDRPLPPQKNFFAHYFTLGSKFRYCGRTEVQSVQ-YGKEKANKDRVFARSPSKPLARK 366
Query: 924 PLSVQAEILKRLSCSELSLYQ---PLQNSSKEKNDKAS--WEEKPREMSKSYHDLSQASL 978
+ E++ R S S+ L P ++ N + S +E R S L +
Sbjct: 367 --LMDWEVVSRNSISDDRLETQSLPSRSPPGTPNHRNSTFTQEGTRLRPSSVGHLVDHMV 424
Query: 979 YPHRKNVIVNMEPPPQTVAE---LVGKPSHQMSRSDAESLAGVTKLNNSKSVASLNRSPE 1035
+ V VN P T A L PS Q + D + A K + S ++ S
Sbjct: 425 HTSPSEVFVNQRSPSSTQANSIVLESSPS-QETPGDGKPPALPPKQSKKNSWNQIHYSHS 483
Query: 1036 RRKHESDSSSIEDPGQAYVLGMTMHSSGNSSSQVPLKENDVLHKRWSIVSSPEREITLVN 1095
++ ES + D SS + P + P + L+
Sbjct: 484 QQDLESHINETFDI--------------PSSPEKPTPNGGI----------PHDNLVLIR 519
Query: 1096 LKKDAKYGLGFQIIGGEKMGRLDLGIFISSVAPGGPADLDGC---LKPGDRLISVNSVSL 1152
+K D GF + GG + + +S VAPG PADL C L GD+++ +N +
Sbjct: 520 MKPDENGRFGFNVKGGYDQ---KMPVIVSRVAPGTPADL--CVPRLNEGDQVVLINGRDI 574
Query: 1153 EGVSHHAAIEILQNAPE----DVTLVISQPKEKISKVPSTPVHLTNEMKNYMKKSSYMQD 1208
+H + ++ + E ++ L++ P+ + E Y+ +
Sbjct: 575 AEHTHDQVVLFIKASCERHSGELMLLVR---------PNAVYDVVEEKLENEPDFQYIPE 625
Query: 1209 SA-IDSSSKDHHWSRGTLRHISE 1230
A +DS +D H R ++ ++E
Sbjct: 626 KAPLDSVHQDDHSLRESMIQLAE 648
Score = 39.7 bits (91), Expect = 0.037
Identities = 33/146 (22%), Positives = 57/146 (39%), Gaps = 11/146 (7%)
Query: 1720 PNKPEFEDSNPSPLPPDMAPGQSYQPQSESASSSSMDKYHIHHISEPTRQENWTPLKNDL 1779
P++ D P LPP + S+ S S ++ + P+ E TP
Sbjct: 452 PSQETPGDGKPPALPPKQSKKNSWNQIHYSHSQQDLESHINETFDIPSSPEKPTPNGGIP 511
Query: 1780 ENHLEDFELEVELLITLIKSEKGSLGFTVTKGNQRIGCYVHDVIQDPAKSD---GRLKPG 1836
++L +LI + E G GF V G + + + +D RL G
Sbjct: 512 HDNL--------VLIRMKPDENGRFGFNVKGGYDQKMPVIVSRVAPGTPADLCVPRLNEG 563
Query: 1837 DRLIKVNDTDVTNMTHTDAVNLLRAA 1862
D+++ +N D+ TH V ++A+
Sbjct: 564 DQVVLINGRDIAEHTHDQVVLFIKAS 589
>gi|109633041 protein tyrosine phosphatase, receptor type, F isoform 1
precursor [Homo sapiens]
Length = 1907
Score = 183 bits (464), Expect = 2e-45
Identities = 94/240 (39%), Positives = 140/240 (58%), Gaps = 12/240 (5%)
Query: 2242 NRRKNRYKNILPYDATRVPLGDEGG-----YINASFIKIPVGKEEFVYIACQGPLPTTVG 2296
N+ KNRY N++ YD +RV L G YINA++I +++ YIA QGPLP T+G
Sbjct: 1375 NKPKNRYANVIAYDHSRVILTSIDGVPGSDYINANYID--GYRKQNAYIATQGPLPETMG 1432
Query: 2297 DFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSNRLRLALVRMQQLKGFV 2356
DFW+M+WEQ++ + MMT+ E ++KC +YWP + T +++ L+ +L +
Sbjct: 1433 DFWRMVWEQRTATVVMMTRLEEKSRVKCDQYWP---ARGTETCGLIQVTLLDTVELATYT 1489
Query: 2357 VRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYMRHIHR--SGPIITHCS 2414
VR L + E R + F AWPDH P P +L F+ ++ + +GP++ HCS
Sbjct: 1490 VRTFALHKSGSSEKRELRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPLDAGPMVVHCS 1549
Query: 2415 AGIGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTEDQYIFCYQVILYVLT 2474
AG+GR+G I ID +L + + DI V CMR QR+ MVQTEDQY+F ++ +L T
Sbjct: 1550 AGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAAT 1609
Score = 150 bits (379), Expect = 2e-35
Identities = 90/241 (37%), Positives = 127/241 (52%), Gaps = 14/241 (5%)
Query: 2242 NRRKNRYKNILPYDATRVPL----GDEGG-YINASFIKIPVGKEEFVYIACQGPLPTTVG 2296
N+ KNR NI+PY+ TRV L G EG YINASF+ +++ YIA QGPL +
Sbjct: 1664 NKFKNRLVNIMPYELTRVCLQPIRGVEGSDYINASFLD--GYRQQKAYIATQGPLAESTE 1721
Query: 2297 DFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSNRLRLALVRMQQLKGFV 2356
DFW+M+WE ST+I M+T+ E + KC +YWP +A M Q ++
Sbjct: 1722 DFWRMLWEHNSTIIVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQ---YI 1778
Query: 2357 VRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYMR----HIHRSGPIITH 2412
+R + D + + R I FT WP+ P + + FI + + GPI H
Sbjct: 1779 LREFKVTDARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQFGQDGPITVH 1838
Query: 2413 CSAGIGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTEDQYIFCYQVILYV 2472
CSAG+GR+G I + +VL + + D+ V+ +R QR MVQTEDQY CY+ L
Sbjct: 1839 CSAGVGRTGVFITLSIVLERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEY 1898
Query: 2473 L 2473
L
Sbjct: 1899 L 1899
>gi|109633039 protein tyrosine phosphatase, receptor type, F isoform 2
precursor [Homo sapiens]
Length = 1898
Score = 183 bits (464), Expect = 2e-45
Identities = 94/240 (39%), Positives = 140/240 (58%), Gaps = 12/240 (5%)
Query: 2242 NRRKNRYKNILPYDATRVPLGDEGG-----YINASFIKIPVGKEEFVYIACQGPLPTTVG 2296
N+ KNRY N++ YD +RV L G YINA++I +++ YIA QGPLP T+G
Sbjct: 1366 NKPKNRYANVIAYDHSRVILTSIDGVPGSDYINANYID--GYRKQNAYIATQGPLPETMG 1423
Query: 2297 DFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSNRLRLALVRMQQLKGFV 2356
DFW+M+WEQ++ + MMT+ E ++KC +YWP + T +++ L+ +L +
Sbjct: 1424 DFWRMVWEQRTATVVMMTRLEEKSRVKCDQYWP---ARGTETCGLIQVTLLDTVELATYT 1480
Query: 2357 VRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYMRHIHR--SGPIITHCS 2414
VR L + E R + F AWPDH P P +L F+ ++ + +GP++ HCS
Sbjct: 1481 VRTFALHKSGSSEKRELRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPLDAGPMVVHCS 1540
Query: 2415 AGIGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTEDQYIFCYQVILYVLT 2474
AG+GR+G I ID +L + + DI V CMR QR+ MVQTEDQY+F ++ +L T
Sbjct: 1541 AGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAAT 1600
Score = 150 bits (379), Expect = 2e-35
Identities = 90/241 (37%), Positives = 127/241 (52%), Gaps = 14/241 (5%)
Query: 2242 NRRKNRYKNILPYDATRVPL----GDEGG-YINASFIKIPVGKEEFVYIACQGPLPTTVG 2296
N+ KNR NI+PY+ TRV L G EG YINASF+ +++ YIA QGPL +
Sbjct: 1655 NKFKNRLVNIMPYELTRVCLQPIRGVEGSDYINASFLD--GYRQQKAYIATQGPLAESTE 1712
Query: 2297 DFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSNRLRLALVRMQQLKGFV 2356
DFW+M+WE ST+I M+T+ E + KC +YWP +A M Q ++
Sbjct: 1713 DFWRMLWEHNSTIIVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQ---YI 1769
Query: 2357 VRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYMR----HIHRSGPIITH 2412
+R + D + + R I FT WP+ P + + FI + + GPI H
Sbjct: 1770 LREFKVTDARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQFGQDGPITVH 1829
Query: 2413 CSAGIGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTEDQYIFCYQVILYV 2472
CSAG+GR+G I + +VL + + D+ V+ +R QR MVQTEDQY CY+ L
Sbjct: 1830 CSAGVGRTGVFITLSIVLERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEY 1889
Query: 2473 L 2473
L
Sbjct: 1890 L 1890
>gi|208431815 protein tyrosine phosphatase, receptor type, K isoform a
[Homo sapiens]
Length = 1446
Score = 182 bits (462), Expect = 4e-45
Identities = 100/246 (40%), Positives = 148/246 (60%), Gaps = 15/246 (6%)
Query: 2236 IGQTKENRRKNRYKNILPYDATRV---PLGDE--GGYINASFIKIPVGKEEFV----YIA 2286
+ + +NR KNRY NI+ YD +RV P+ D+ YINA++I I + ++ + YIA
Sbjct: 905 VAKKDQNRAKNRYGNIIAYDHSRVILQPVEDDPSSDYINANYIDIWLYRDGYQRPSHYIA 964
Query: 2287 CQGPLPTTVGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSNRLRLAL 2346
QGP+ TV DFW+MIW+++S I M+T VE ++KC +YWP+ T V ++
Sbjct: 965 TQGPVHETVYDFWRMIWQEQSACIVMVTNLVEVGRVKCYKYWPD----DTEVYGDFKVTC 1020
Query: 2347 VRMQQLKGFVVRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYMRHIH-- 2404
V M+ L +VVR TLE E+R + +FT WPDH P LL+FI ++ +
Sbjct: 1021 VEMEPLAEYVVRTFTLERRGYNEIREVKQFHFTGWPDHGVPYHATGLLSFIRRVKLSNPP 1080
Query: 2405 RSGPIITHCSAGIGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTEDQYIF 2464
+GPI+ HCSAG GR+G I ID++L + ++ DI + V+ +R +R MVQTE+QYIF
Sbjct: 1081 SAGPIVVHCSAGAGRTGCYIVIDIMLDMAEREGVVDIYNCVKALRSRRINMVQTEEQYIF 1140
Query: 2465 CYQVIL 2470
+ IL
Sbjct: 1141 IHDAIL 1146
Score = 84.7 bits (208), Expect = 1e-15
Identities = 71/274 (25%), Positives = 114/274 (41%), Gaps = 34/274 (12%)
Query: 2221 ELENLQELKP---LDQCLIGQTKENRRKNRYKNILPYDATRVPL----GDEGGYINASFI 2273
E + L + P + C I N KNR+ ++LP D L G+ YINA+ +
Sbjct: 1183 EFQTLNSVTPRLQAEDCSIACLPRNHDKNRFMDMLPPDRCLPFLITIDGESSNYINAALM 1242
Query: 2274 KIPVGKEEFVYIACQGPLPTTVGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILG 2333
++ +I Q PLP TV DFW+++++ T I M+ EV+ + C +YWP
Sbjct: 1243 DSY--RQPAAFIVTQYPLPNTVKDFWRLVYDYGCTSIVML-NEVDLSQ-GCPQYWPE--- 1295
Query: 2334 KTTMVSNRLRLALVRMQQLK--------GFVVRAMTLEDIQTREVRHISHLNFTAWPDH- 2384
LR ++++ + + R L Q + + + W H
Sbjct: 1296 -----EGMLRYGPIQVECMSCSMDCDVINRIFRICNLTRPQEGYLM-VQQFQYLGWASHR 1349
Query: 2385 DTPSQPDDLLTFISYMRHIHR-----SGPIITHCSAGIGRSGTLICIDVVLGLISQDLDF 2439
+ P L I + G I HC G GRSG I +V+ ++ +
Sbjct: 1350 EVPGSKRSFLKLILQVEKWQEECEEGEGRTIIHCLNGGGRSGMFCAIGIVVEMVKRQNVV 1409
Query: 2440 DISDLVRCMRLQRHGMVQTEDQYIFCYQVILYVL 2473
D+ V+ +R + MV+ +QY FCY V L L
Sbjct: 1410 DVFHAVKTLRNSKPNMVEAPEQYRFCYDVALEYL 1443
>gi|18104993 protein tyrosine phosphatase, non-receptor type 6 isoform
3 [Homo sapiens]
Length = 624
Score = 182 bits (462), Expect = 4e-45
Identities = 116/289 (40%), Positives = 160/289 (55%), Gaps = 23/289 (7%)
Query: 2220 KELENLQ--ELKPLDQCLIGQTKENRRKNRYKNILPYDATRVPLGDEGG------YINAS 2271
+E E+LQ E+K L Q L GQ EN+ KNRYKNILP+D +RV L YINA+
Sbjct: 246 EEFESLQKQEVKNLHQRLEGQRPENKGKNRYKNILPFDHSRVILQGRDSNIPGSDYINAN 305
Query: 2272 FIKIPV-GKEEFV--YIACQGPLPTTVGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYW 2328
+IK + G +E YIA QG L TV DFWQM W++ S VI M T+EVE + KC YW
Sbjct: 306 YIKNQLLGPDENAKTYIASQGCLEATVNDFWQMAWQENSRVIVMTTREVEKGRNKCVPYW 365
Query: 2329 PNILGKTTMVSNRLRLALVRMQQLKGFVVRAMTLEDIQTRE-VRHISHLNFTAWPDHDTP 2387
P + + + +R + + + + +R I H + +WPDH P
Sbjct: 366 PEV--GMQRAYGPYSVTNCGEHDTTEYKLRTLQVSPLDNGDLIREIWHYQYLSWPDHGVP 423
Query: 2388 SQPDDLLTFISYMRH----IHRSGPIITHCSAGIGRSGTLICIDVVLGLISQ---DLDFD 2440
S+P +L+F+ + + +GPII HCSAGIGR+GT+I ID+++ IS D D D
Sbjct: 424 SEPGGVLSFLDQINQRQESLPHAGPIIVHCSAGIGRTGTIIVIDMLMENISTKGLDCDID 483
Query: 2441 ISDLVRCMRLQRHGMVQTEDQYIFCYQVILYVL--TRLQAEEEQKQQPQ 2487
I ++ +R QR GMVQTE QY F Y I + T+ + E Q Q+ Q
Sbjct: 484 IQKTIQMVRAQRSGMVQTEAQYKFIYVAIAQFIETTKKKLEVLQSQKGQ 532
>gi|18104989 protein tyrosine phosphatase, non-receptor type 6 isoform
1 [Homo sapiens]
Length = 595
Score = 182 bits (462), Expect = 4e-45
Identities = 116/289 (40%), Positives = 160/289 (55%), Gaps = 23/289 (7%)
Query: 2220 KELENLQ--ELKPLDQCLIGQTKENRRKNRYKNILPYDATRVPLGDEGG------YINAS 2271
+E E+LQ E+K L Q L GQ EN+ KNRYKNILP+D +RV L YINA+
Sbjct: 246 EEFESLQKQEVKNLHQRLEGQRPENKGKNRYKNILPFDHSRVILQGRDSNIPGSDYINAN 305
Query: 2272 FIKIPV-GKEEFV--YIACQGPLPTTVGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYW 2328
+IK + G +E YIA QG L TV DFWQM W++ S VI M T+EVE + KC YW
Sbjct: 306 YIKNQLLGPDENAKTYIASQGCLEATVNDFWQMAWQENSRVIVMTTREVEKGRNKCVPYW 365
Query: 2329 PNILGKTTMVSNRLRLALVRMQQLKGFVVRAMTLEDIQTRE-VRHISHLNFTAWPDHDTP 2387
P + + + +R + + + + +R I H + +WPDH P
Sbjct: 366 PEV--GMQRAYGPYSVTNCGEHDTTEYKLRTLQVSPLDNGDLIREIWHYQYLSWPDHGVP 423
Query: 2388 SQPDDLLTFISYMRH----IHRSGPIITHCSAGIGRSGTLICIDVVLGLISQ---DLDFD 2440
S+P +L+F+ + + +GPII HCSAGIGR+GT+I ID+++ IS D D D
Sbjct: 424 SEPGGVLSFLDQINQRQESLPHAGPIIVHCSAGIGRTGTIIVIDMLMENISTKGLDCDID 483
Query: 2441 ISDLVRCMRLQRHGMVQTEDQYIFCYQVILYVL--TRLQAEEEQKQQPQ 2487
I ++ +R QR GMVQTE QY F Y I + T+ + E Q Q+ Q
Sbjct: 484 IQKTIQMVRAQRSGMVQTEAQYKFIYVAIAQFIETTKKKLEVLQSQKGQ 532
>gi|18104991 protein tyrosine phosphatase, non-receptor type 6 isoform
2 [Homo sapiens]
Length = 597
Score = 182 bits (462), Expect = 4e-45
Identities = 116/289 (40%), Positives = 160/289 (55%), Gaps = 23/289 (7%)
Query: 2220 KELENLQ--ELKPLDQCLIGQTKENRRKNRYKNILPYDATRVPLGDEGG------YINAS 2271
+E E+LQ E+K L Q L GQ EN+ KNRYKNILP+D +RV L YINA+
Sbjct: 248 EEFESLQKQEVKNLHQRLEGQRPENKGKNRYKNILPFDHSRVILQGRDSNIPGSDYINAN 307
Query: 2272 FIKIPV-GKEEFV--YIACQGPLPTTVGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYW 2328
+IK + G +E YIA QG L TV DFWQM W++ S VI M T+EVE + KC YW
Sbjct: 308 YIKNQLLGPDENAKTYIASQGCLEATVNDFWQMAWQENSRVIVMTTREVEKGRNKCVPYW 367
Query: 2329 PNILGKTTMVSNRLRLALVRMQQLKGFVVRAMTLEDIQTRE-VRHISHLNFTAWPDHDTP 2387
P + + + +R + + + + +R I H + +WPDH P
Sbjct: 368 PEV--GMQRAYGPYSVTNCGEHDTTEYKLRTLQVSPLDNGDLIREIWHYQYLSWPDHGVP 425
Query: 2388 SQPDDLLTFISYMRH----IHRSGPIITHCSAGIGRSGTLICIDVVLGLISQ---DLDFD 2440
S+P +L+F+ + + +GPII HCSAGIGR+GT+I ID+++ IS D D D
Sbjct: 426 SEPGGVLSFLDQINQRQESLPHAGPIIVHCSAGIGRTGTIIVIDMLMENISTKGLDCDID 485
Query: 2441 ISDLVRCMRLQRHGMVQTEDQYIFCYQVILYVL--TRLQAEEEQKQQPQ 2487
I ++ +R QR GMVQTE QY F Y I + T+ + E Q Q+ Q
Sbjct: 486 IQKTIQMVRAQRSGMVQTEAQYKFIYVAIAQFIETTKKKLEVLQSQKGQ 534
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.130 0.371
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 97,222,445
Number of Sequences: 37866
Number of extensions: 4624943
Number of successful extensions: 15782
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 274
Number of HSP's successfully gapped in prelim test: 194
Number of HSP's that attempted gapping in prelim test: 12991
Number of HSP's gapped (non-prelim): 2172
length of query: 2490
length of database: 18,247,518
effective HSP length: 119
effective length of query: 2371
effective length of database: 13,741,464
effective search space: 32581011144
effective search space used: 32581011144
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 71 (32.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.