Search of human proteins with 18375646

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|18375646 protein tyrosine phosphatase, non-receptor type 13
isoform 1 [Homo sapiens]
         (2485 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|18375646 protein tyrosine phosphatase, non-receptor type 13 i...  4941   0.0  
gi|18375650 protein tyrosine phosphatase, non-receptor type 13 i...  4935   0.0  
gi|5453992 protein tyrosine phosphatase, non-receptor type 13 is...  4892   0.0  
gi|18375648 protein tyrosine phosphatase, non-receptor type 13 i...  2820   0.0  
gi|110346438 FERM and PDZ domain containing 2 isoform 1 [Homo sa...   297   8e-80
gi|110346436 FERM and PDZ domain containing 2 isoform 3 [Homo sa...   297   8e-80
gi|109138573 protein tyrosine phosphatase, non-receptor type 20A...   239   3e-62
gi|109138561 protein tyrosine phosphatase, non-receptor type 20A...   239   3e-62
gi|109138557 protein tyrosine phosphatase, non-receptor type 20A...   239   3e-62
gi|108802617 protein tyrosine phosphatase, non-receptor type 20 ...   239   3e-62
gi|108802607 protein tyrosine phosphatase, non-receptor type 20 ...   239   3e-62
gi|108802604 protein tyrosine phosphatase, non-receptor type 20 ...   239   3e-62
gi|108802611 protein tyrosine phosphatase, non-receptor type 20 ...   214   6e-55
gi|109138565 protein tyrosine phosphatase, non-receptor type 20A...   214   6e-55
gi|241896926 protein tyrosine phosphatase, receptor type, H isof...   194   1e-48
gi|241896924 protein tyrosine phosphatase, receptor type, H isof...   194   1e-48
gi|223941891 protein tyrosine phosphatase, non-receptor type 3 i...   190   2e-47
gi|223941888 protein tyrosine phosphatase, non-receptor type 3 i...   190   2e-47
gi|223941885 protein tyrosine phosphatase, non-receptor type 3 i...   190   2e-47
gi|223941882 protein tyrosine phosphatase, non-receptor type 3 i...   190   2e-47
gi|223941879 protein tyrosine phosphatase, non-receptor type 3 i...   190   2e-47
gi|223941876 protein tyrosine phosphatase, non-receptor type 3 i...   190   2e-47
gi|33356177 protein tyrosine phosphatase, non-receptor type 11 [...   189   3e-47
gi|4506295 protein tyrosine phosphatase, non-receptor type 4 [Ho...   186   2e-46
gi|109633041 protein tyrosine phosphatase, receptor type, F isof...   183   2e-45
gi|109633039 protein tyrosine phosphatase, receptor type, F isof...   183   2e-45
gi|208431815 protein tyrosine phosphatase, receptor type, K isof...   182   4e-45
gi|18104993 protein tyrosine phosphatase, non-receptor type 6 is...   182   4e-45
gi|18104989 protein tyrosine phosphatase, non-receptor type 6 is...   182   4e-45
gi|18104991 protein tyrosine phosphatase, non-receptor type 6 is...   182   4e-45

>gi|18375646 protein tyrosine phosphatase, non-receptor type 13
            isoform 1 [Homo sapiens]
          Length = 2485

 Score = 4941 bits (12816), Expect = 0.0
 Identities = 2485/2485 (100%), Positives = 2485/2485 (100%)

Query: 1    MHVSLAEALEVRGGPLQEEEIWAVLNQSAESLQELFRKVSLADPAALGFIISPWSLLLLP 60
            MHVSLAEALEVRGGPLQEEEIWAVLNQSAESLQELFRKVSLADPAALGFIISPWSLLLLP
Sbjct: 1    MHVSLAEALEVRGGPLQEEEIWAVLNQSAESLQELFRKVSLADPAALGFIISPWSLLLLP 60

Query: 61   SGSVSFTDENISNQDLRAFTAPEVLQNQSLTSLSDVEKIHIYSLGMTLYWGADYEVPQSQ 120
            SGSVSFTDENISNQDLRAFTAPEVLQNQSLTSLSDVEKIHIYSLGMTLYWGADYEVPQSQ
Sbjct: 61   SGSVSFTDENISNQDLRAFTAPEVLQNQSLTSLSDVEKIHIYSLGMTLYWGADYEVPQSQ 120

Query: 121  PIKLGDHLNSILLGMCEDVIYARVSVRTVLDACSAHIRNSNCAPSFSYVKHLVKLVLGNL 180
            PIKLGDHLNSILLGMCEDVIYARVSVRTVLDACSAHIRNSNCAPSFSYVKHLVKLVLGNL
Sbjct: 121  PIKLGDHLNSILLGMCEDVIYARVSVRTVLDACSAHIRNSNCAPSFSYVKHLVKLVLGNL 180

Query: 181  SGTDQLSCNSEQKPDRSQAIRDRLRGKGLPTGRSSTSDVLDIQKPPLSHQTFLNKGLSKS 240
            SGTDQLSCNSEQKPDRSQAIRDRLRGKGLPTGRSSTSDVLDIQKPPLSHQTFLNKGLSKS
Sbjct: 181  SGTDQLSCNSEQKPDRSQAIRDRLRGKGLPTGRSSTSDVLDIQKPPLSHQTFLNKGLSKS 240

Query: 241  MGFLSIKDTQDENYFKDILSDNSGREDSENTFSPYQFKTSGPEKKPIPGIDVLSKKKIWA 300
            MGFLSIKDTQDENYFKDILSDNSGREDSENTFSPYQFKTSGPEKKPIPGIDVLSKKKIWA
Sbjct: 241  MGFLSIKDTQDENYFKDILSDNSGREDSENTFSPYQFKTSGPEKKPIPGIDVLSKKKIWA 300

Query: 301  SSMDLLCTADRDFSSGETATYRRCHPEAVTVRTSTTPRKKEARYSDGSIALDIFGPQKMD 360
            SSMDLLCTADRDFSSGETATYRRCHPEAVTVRTSTTPRKKEARYSDGSIALDIFGPQKMD
Sbjct: 301  SSMDLLCTADRDFSSGETATYRRCHPEAVTVRTSTTPRKKEARYSDGSIALDIFGPQKMD 360

Query: 361  PIYHTRELPTSSAISSALDRIRERQKKLQVLREAMNVEEPVRRYKTYHGDVFSTSSESPS 420
            PIYHTRELPTSSAISSALDRIRERQKKLQVLREAMNVEEPVRRYKTYHGDVFSTSSESPS
Sbjct: 361  PIYHTRELPTSSAISSALDRIRERQKKLQVLREAMNVEEPVRRYKTYHGDVFSTSSESPS 420

Query: 421  IISSESDFRQVRRSEASKRFESSSGLPGVDETLSQGQSQRPSRQYETPFEGNLINQEIML 480
            IISSESDFRQVRRSEASKRFESSSGLPGVDETLSQGQSQRPSRQYETPFEGNLINQEIML
Sbjct: 421  IISSESDFRQVRRSEASKRFESSSGLPGVDETLSQGQSQRPSRQYETPFEGNLINQEIML 480

Query: 481  KRQEEELMQLQAKMALRQSRLSLYPGDTIKASMLDITRDPLREIALETAMTQRKLRNFFG 540
            KRQEEELMQLQAKMALRQSRLSLYPGDTIKASMLDITRDPLREIALETAMTQRKLRNFFG
Sbjct: 481  KRQEEELMQLQAKMALRQSRLSLYPGDTIKASMLDITRDPLREIALETAMTQRKLRNFFG 540

Query: 541  PEFVKMTIEPFISLDLPRSILTKKGKNEDNRRKVNIMLLNGQRLELTCDTKTICKDVFDM 600
            PEFVKMTIEPFISLDLPRSILTKKGKNEDNRRKVNIMLLNGQRLELTCDTKTICKDVFDM
Sbjct: 541  PEFVKMTIEPFISLDLPRSILTKKGKNEDNRRKVNIMLLNGQRLELTCDTKTICKDVFDM 600

Query: 601  VVAHIGLVEHHLFALATLKDNEYFFVDPDLKLTKVAPEGWKEEPKKKTKATVNFTLFFRI 660
            VVAHIGLVEHHLFALATLKDNEYFFVDPDLKLTKVAPEGWKEEPKKKTKATVNFTLFFRI
Sbjct: 601  VVAHIGLVEHHLFALATLKDNEYFFVDPDLKLTKVAPEGWKEEPKKKTKATVNFTLFFRI 660

Query: 661  KFFMDDVSLIQHTLTCHQYYLQLRKDILEERMHCDDETSLLLASLALQAEYGDYQPEVHG 720
            KFFMDDVSLIQHTLTCHQYYLQLRKDILEERMHCDDETSLLLASLALQAEYGDYQPEVHG
Sbjct: 661  KFFMDDVSLIQHTLTCHQYYLQLRKDILEERMHCDDETSLLLASLALQAEYGDYQPEVHG 720

Query: 721  VSYFRMEHYLPARVMEKLDLSYIKEELPKLHNTYVGASEKETELEFLKVCQRLTEYGVHF 780
            VSYFRMEHYLPARVMEKLDLSYIKEELPKLHNTYVGASEKETELEFLKVCQRLTEYGVHF
Sbjct: 721  VSYFRMEHYLPARVMEKLDLSYIKEELPKLHNTYVGASEKETELEFLKVCQRLTEYGVHF 780

Query: 781  HRVHPEKKSQTGILLGVCSKGVLVFEVHNGVRTLVLRFPWRETKKISFSKKKITLQNTSD 840
            HRVHPEKKSQTGILLGVCSKGVLVFEVHNGVRTLVLRFPWRETKKISFSKKKITLQNTSD
Sbjct: 781  HRVHPEKKSQTGILLGVCSKGVLVFEVHNGVRTLVLRFPWRETKKISFSKKKITLQNTSD 840

Query: 841  GIKHGFQTDNSKICQYLLHLCSYQHKFQLQMRARQSNQDAQDIERASFRSLNLQAESVRG 900
            GIKHGFQTDNSKICQYLLHLCSYQHKFQLQMRARQSNQDAQDIERASFRSLNLQAESVRG
Sbjct: 841  GIKHGFQTDNSKICQYLLHLCSYQHKFQLQMRARQSNQDAQDIERASFRSLNLQAESVRG 900

Query: 901  FNMGRAISTGSLASSTLNKLAVRPLSVQAEILKRLSCSELSLYQPLQNSSKEKNDKASWE 960
            FNMGRAISTGSLASSTLNKLAVRPLSVQAEILKRLSCSELSLYQPLQNSSKEKNDKASWE
Sbjct: 901  FNMGRAISTGSLASSTLNKLAVRPLSVQAEILKRLSCSELSLYQPLQNSSKEKNDKASWE 960

Query: 961  EKPREMSKSYHDLSQASLYPHRKNVIVNMEPPPQTVAELVGKPSHQMSRSDAESLAGVTK 1020
            EKPREMSKSYHDLSQASLYPHRKNVIVNMEPPPQTVAELVGKPSHQMSRSDAESLAGVTK
Sbjct: 961  EKPREMSKSYHDLSQASLYPHRKNVIVNMEPPPQTVAELVGKPSHQMSRSDAESLAGVTK 1020

Query: 1021 LNNSKSVASLNRSPERRKHESDSSSIEDPGQAYVLGMTMHSSGNSSSQVPLKENDVLHKR 1080
            LNNSKSVASLNRSPERRKHESDSSSIEDPGQAYVLGMTMHSSGNSSSQVPLKENDVLHKR
Sbjct: 1021 LNNSKSVASLNRSPERRKHESDSSSIEDPGQAYVLGMTMHSSGNSSSQVPLKENDVLHKR 1080

Query: 1081 WSIVSSPEREITLVNLKKDAKYGLGFQIIGGEKMGRLDLGIFISSVAPGGPADLDGCLKP 1140
            WSIVSSPEREITLVNLKKDAKYGLGFQIIGGEKMGRLDLGIFISSVAPGGPADLDGCLKP
Sbjct: 1081 WSIVSSPEREITLVNLKKDAKYGLGFQIIGGEKMGRLDLGIFISSVAPGGPADLDGCLKP 1140

Query: 1141 GDRLISVNSVSLEGVSHHAAIEILQNAPEDVTLVISQPKEKISKVPSTPVHLTNEMKNYM 1200
            GDRLISVNSVSLEGVSHHAAIEILQNAPEDVTLVISQPKEKISKVPSTPVHLTNEMKNYM
Sbjct: 1141 GDRLISVNSVSLEGVSHHAAIEILQNAPEDVTLVISQPKEKISKVPSTPVHLTNEMKNYM 1200

Query: 1201 KKSSYMQDSAIDSSSKDHHWSRGTLRHISENSFGPSGGLREGSLSSQDSRTESASLSQSQ 1260
            KKSSYMQDSAIDSSSKDHHWSRGTLRHISENSFGPSGGLREGSLSSQDSRTESASLSQSQ
Sbjct: 1201 KKSSYMQDSAIDSSSKDHHWSRGTLRHISENSFGPSGGLREGSLSSQDSRTESASLSQSQ 1260

Query: 1261 VNGFFASHLGDQTWQESQHGSPSPSVISKATEKETFTDSNQSKTKKPGISDVTDYSDRGD 1320
            VNGFFASHLGDQTWQESQHGSPSPSVISKATEKETFTDSNQSKTKKPGISDVTDYSDRGD
Sbjct: 1261 VNGFFASHLGDQTWQESQHGSPSPSVISKATEKETFTDSNQSKTKKPGISDVTDYSDRGD 1320

Query: 1321 SDMDEATYSSSQDHQTPKQESSSSVNTSNKMNFKTFSSSPPKPGDIFEVELAKNDNSLGI 1380
            SDMDEATYSSSQDHQTPKQESSSSVNTSNKMNFKTFSSSPPKPGDIFEVELAKNDNSLGI
Sbjct: 1321 SDMDEATYSSSQDHQTPKQESSSSVNTSNKMNFKTFSSSPPKPGDIFEVELAKNDNSLGI 1380

Query: 1381 SVTGGVNTSVRHGGIYVKAVIPQGAAESDGRIHKGDRVLAVNGVSLEGATHKQAVETLRN 1440
            SVTGGVNTSVRHGGIYVKAVIPQGAAESDGRIHKGDRVLAVNGVSLEGATHKQAVETLRN
Sbjct: 1381 SVTGGVNTSVRHGGIYVKAVIPQGAAESDGRIHKGDRVLAVNGVSLEGATHKQAVETLRN 1440

Query: 1441 TGQVVHLLLEKGQSPTSKEHVPVTPQCTLSDQNAQGQGPEKVKKTTQVKDYSFVTEENTF 1500
            TGQVVHLLLEKGQSPTSKEHVPVTPQCTLSDQNAQGQGPEKVKKTTQVKDYSFVTEENTF
Sbjct: 1441 TGQVVHLLLEKGQSPTSKEHVPVTPQCTLSDQNAQGQGPEKVKKTTQVKDYSFVTEENTF 1500

Query: 1501 EVKLFKNSSGLGFSFSREDNLIPEQINASIVRVKKLFPGQPAAESGKIDVGDVILKVNGA 1560
            EVKLFKNSSGLGFSFSREDNLIPEQINASIVRVKKLFPGQPAAESGKIDVGDVILKVNGA
Sbjct: 1501 EVKLFKNSSGLGFSFSREDNLIPEQINASIVRVKKLFPGQPAAESGKIDVGDVILKVNGA 1560

Query: 1561 SLKGLSQQEVISALRGTAPEVFLLLCRPPPGVLPEIDTALLTPLQSPAQVLPNSSKDSSQ 1620
            SLKGLSQQEVISALRGTAPEVFLLLCRPPPGVLPEIDTALLTPLQSPAQVLPNSSKDSSQ
Sbjct: 1561 SLKGLSQQEVISALRGTAPEVFLLLCRPPPGVLPEIDTALLTPLQSPAQVLPNSSKDSSQ 1620

Query: 1621 PSCVEQSTSSDENEMSDKSKKQCKSPSRRDSYSDSSGSGEDDLVTAPANISNSTWSSALH 1680
            PSCVEQSTSSDENEMSDKSKKQCKSPSRRDSYSDSSGSGEDDLVTAPANISNSTWSSALH
Sbjct: 1621 PSCVEQSTSSDENEMSDKSKKQCKSPSRRDSYSDSSGSGEDDLVTAPANISNSTWSSALH 1680

Query: 1681 QTLSNMVSQAQSHHEAPKSQEDTICTMFYYPQKIPNKPEFEDSNPSPLPPDMAPGQSYQP 1740
            QTLSNMVSQAQSHHEAPKSQEDTICTMFYYPQKIPNKPEFEDSNPSPLPPDMAPGQSYQP
Sbjct: 1681 QTLSNMVSQAQSHHEAPKSQEDTICTMFYYPQKIPNKPEFEDSNPSPLPPDMAPGQSYQP 1740

Query: 1741 QSESASSSSMDKYHIHHISEPTRQENWTPLKNDLENHLEDFELEVELLITLIKSEKGSLG 1800
            QSESASSSSMDKYHIHHISEPTRQENWTPLKNDLENHLEDFELEVELLITLIKSEKGSLG
Sbjct: 1741 QSESASSSSMDKYHIHHISEPTRQENWTPLKNDLENHLEDFELEVELLITLIKSEKGSLG 1800

Query: 1801 FTVTKGNQRIGCYVHDVIQDPAKSDGRLKPGDRLIKVNDTDVTNMTHTDAVNLLRAASKT 1860
            FTVTKGNQRIGCYVHDVIQDPAKSDGRLKPGDRLIKVNDTDVTNMTHTDAVNLLRAASKT
Sbjct: 1801 FTVTKGNQRIGCYVHDVIQDPAKSDGRLKPGDRLIKVNDTDVTNMTHTDAVNLLRAASKT 1860

Query: 1861 VRLVIGRVLELPRIPMLPHLLPDITLTCNKEELGFSLCGGHDSLYQVVYISDINPRSVAA 1920
            VRLVIGRVLELPRIPMLPHLLPDITLTCNKEELGFSLCGGHDSLYQVVYISDINPRSVAA
Sbjct: 1861 VRLVIGRVLELPRIPMLPHLLPDITLTCNKEELGFSLCGGHDSLYQVVYISDINPRSVAA 1920

Query: 1921 IEGNLQLLDVIHYVNGVSTQGMTLEEVNRALDMSLPSLVLKATRNDLPVVPSSKRSAVSA 1980
            IEGNLQLLDVIHYVNGVSTQGMTLEEVNRALDMSLPSLVLKATRNDLPVVPSSKRSAVSA
Sbjct: 1921 IEGNLQLLDVIHYVNGVSTQGMTLEEVNRALDMSLPSLVLKATRNDLPVVPSSKRSAVSA 1980

Query: 1981 PKSTKGNGSYSVGSCSQPALTPNDSFSTVAGEEINEISYPKGKCSTYQIKGSPNLTLPKE 2040
            PKSTKGNGSYSVGSCSQPALTPNDSFSTVAGEEINEISYPKGKCSTYQIKGSPNLTLPKE
Sbjct: 1981 PKSTKGNGSYSVGSCSQPALTPNDSFSTVAGEEINEISYPKGKCSTYQIKGSPNLTLPKE 2040

Query: 2041 SYIQEDDIYDDSQEAEVIQSLLDVVDEEAQNLLNENNAAGYSCGPGTLKMNGKLSEERTE 2100
            SYIQEDDIYDDSQEAEVIQSLLDVVDEEAQNLLNENNAAGYSCGPGTLKMNGKLSEERTE
Sbjct: 2041 SYIQEDDIYDDSQEAEVIQSLLDVVDEEAQNLLNENNAAGYSCGPGTLKMNGKLSEERTE 2100

Query: 2101 DTDCDGSPLPEYFTEATKMNGCEEYCEEKVKSESLIQKPQEKKTDDDEITWGNDELPIER 2160
            DTDCDGSPLPEYFTEATKMNGCEEYCEEKVKSESLIQKPQEKKTDDDEITWGNDELPIER
Sbjct: 2101 DTDCDGSPLPEYFTEATKMNGCEEYCEEKVKSESLIQKPQEKKTDDDEITWGNDELPIER 2160

Query: 2161 TNHEDSDKDHSFLTNDELAVLPVVKVLPSGKYTGANLKSVIRVLRGLLDQGIPSKELENL 2220
            TNHEDSDKDHSFLTNDELAVLPVVKVLPSGKYTGANLKSVIRVLRGLLDQGIPSKELENL
Sbjct: 2161 TNHEDSDKDHSFLTNDELAVLPVVKVLPSGKYTGANLKSVIRVLRGLLDQGIPSKELENL 2220

Query: 2221 QELKPLDQCLIGQTKENRRKNRYKNILPYDATRVPLGDEGGYINASFIKIPVGKEEFVYI 2280
            QELKPLDQCLIGQTKENRRKNRYKNILPYDATRVPLGDEGGYINASFIKIPVGKEEFVYI
Sbjct: 2221 QELKPLDQCLIGQTKENRRKNRYKNILPYDATRVPLGDEGGYINASFIKIPVGKEEFVYI 2280

Query: 2281 ACQGPLPTTVGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSNRLRLA 2340
            ACQGPLPTTVGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSNRLRLA
Sbjct: 2281 ACQGPLPTTVGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSNRLRLA 2340

Query: 2341 LVRMQQLKGFVVRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYMRHIHR 2400
            LVRMQQLKGFVVRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYMRHIHR
Sbjct: 2341 LVRMQQLKGFVVRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYMRHIHR 2400

Query: 2401 SGPIITHCSAGIGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTEDQYIFC 2460
            SGPIITHCSAGIGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTEDQYIFC
Sbjct: 2401 SGPIITHCSAGIGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTEDQYIFC 2460

Query: 2461 YQVILYVLTRLQAEEEQKQQPQLLK 2485
            YQVILYVLTRLQAEEEQKQQPQLLK
Sbjct: 2461 YQVILYVLTRLQAEEEQKQQPQLLK 2485


>gi|18375650 protein tyrosine phosphatase, non-receptor type 13
            isoform 4 [Homo sapiens]
          Length = 2490

 Score = 4935 bits (12800), Expect = 0.0
 Identities = 2485/2490 (99%), Positives = 2485/2490 (99%), Gaps = 5/2490 (0%)

Query: 1    MHVSLAEALEVRGGPLQEEEIWAVLNQSAESLQELFRKVSLADPAALGFIISPWSLLLLP 60
            MHVSLAEALEVRGGPLQEEEIWAVLNQSAESLQELFRKVSLADPAALGFIISPWSLLLLP
Sbjct: 1    MHVSLAEALEVRGGPLQEEEIWAVLNQSAESLQELFRKVSLADPAALGFIISPWSLLLLP 60

Query: 61   SGSVSFTDENISNQDLRAFTAPEVLQNQSLTSLSDVEKIHIYSLGMTLYWGADYEVPQSQ 120
            SGSVSFTDENISNQDLRAFTAPEVLQNQSLTSLSDVEKIHIYSLGMTLYWGADYEVPQSQ
Sbjct: 61   SGSVSFTDENISNQDLRAFTAPEVLQNQSLTSLSDVEKIHIYSLGMTLYWGADYEVPQSQ 120

Query: 121  PIKLGDHLNSILLGMCEDVIYARVSVRTVLDACSAHIRNSNCAPSFSYVKHLVKLVLGNL 180
            PIKLGDHLNSILLGMCEDVIYARVSVRTVLDACSAHIRNSNCAPSFSYVKHLVKLVLGNL
Sbjct: 121  PIKLGDHLNSILLGMCEDVIYARVSVRTVLDACSAHIRNSNCAPSFSYVKHLVKLVLGNL 180

Query: 181  SGTDQLSCNSEQKPDRSQAIRDRLRGKGLPTGRSSTSDVLDIQKPPLSHQTFLNKGLSKS 240
            SGTDQLSCNSEQKPDRSQAIRDRLRGKGLPTGRSSTSDVLDIQKPPLSHQTFLNKGLSKS
Sbjct: 181  SGTDQLSCNSEQKPDRSQAIRDRLRGKGLPTGRSSTSDVLDIQKPPLSHQTFLNKGLSKS 240

Query: 241  MGFLSIKDTQDENYFKDILSDNSGREDSENTFSPYQFKTSGPEKKPIPGIDVLSKKKIWA 300
            MGFLSIKDTQDENYFKDILSDNSGREDSENTFSPYQFKTSGPEKKPIPGIDVLSKKKIWA
Sbjct: 241  MGFLSIKDTQDENYFKDILSDNSGREDSENTFSPYQFKTSGPEKKPIPGIDVLSKKKIWA 300

Query: 301  SSMDLLCTADRDFSSGETATYRRCHPEAVTVRTSTTPRKKEARYSDGSIALDIFGPQKMD 360
            SSMDLLCTADRDFSSGETATYRRCHPEAVTVRTSTTPRKKEARYSDGSIALDIFGPQKMD
Sbjct: 301  SSMDLLCTADRDFSSGETATYRRCHPEAVTVRTSTTPRKKEARYSDGSIALDIFGPQKMD 360

Query: 361  PIYHTRELPTSSAISSALDRIRERQKKLQVLREAMNVEEPVRRYKTYHGDVFSTSSESPS 420
            PIYHTRELPTSSAISSALDRIRERQKKLQVLREAMNVEEPVRRYKTYHGDVFSTSSESPS
Sbjct: 361  PIYHTRELPTSSAISSALDRIRERQKKLQVLREAMNVEEPVRRYKTYHGDVFSTSSESPS 420

Query: 421  IISSESDFRQVRRSEASKRFESSSGLPGVDETLSQGQSQRPSRQYETPFEGNLINQEIML 480
            IISSESDFRQVRRSEASKRFESSSGLPGVDETLSQGQSQRPSRQYETPFEGNLINQEIML
Sbjct: 421  IISSESDFRQVRRSEASKRFESSSGLPGVDETLSQGQSQRPSRQYETPFEGNLINQEIML 480

Query: 481  KRQEEELMQLQAKMALRQSRLSLYPGDTIKASMLDITRDPLREIALETAMTQRKLRNFFG 540
            KRQEEELMQLQAKMALRQSRLSLYPGDTIKASMLDITRDPLREIALETAMTQRKLRNFFG
Sbjct: 481  KRQEEELMQLQAKMALRQSRLSLYPGDTIKASMLDITRDPLREIALETAMTQRKLRNFFG 540

Query: 541  PEFVKMTIEPFISLDLPRSILTKKGKNEDNRRKVNIMLLNGQRLELTCDTKTICKDVFDM 600
            PEFVKMTIEPFISLDLPRSILTKKGKNEDNRRKVNIMLLNGQRLELTCDTKTICKDVFDM
Sbjct: 541  PEFVKMTIEPFISLDLPRSILTKKGKNEDNRRKVNIMLLNGQRLELTCDTKTICKDVFDM 600

Query: 601  VVAHIGLVEHHLFALATLKDNEYFFVDPDLKLTKVAPEGWKEEPKKKTKATVNFTLFFRI 660
            VVAHIGLVEHHLFALATLKDNEYFFVDPDLKLTKVAPEGWKEEPKKKTKATVNFTLFFRI
Sbjct: 601  VVAHIGLVEHHLFALATLKDNEYFFVDPDLKLTKVAPEGWKEEPKKKTKATVNFTLFFRI 660

Query: 661  KFFMDDVSLIQHTLTCHQYYLQLRKDILEERMHCDDETSLLLASLALQAEYGDYQPEVHG 720
            KFFMDDVSLIQHTLTCHQYYLQLRKDILEERMHCDDETSLLLASLALQAEYGDYQPEVHG
Sbjct: 661  KFFMDDVSLIQHTLTCHQYYLQLRKDILEERMHCDDETSLLLASLALQAEYGDYQPEVHG 720

Query: 721  VSYFRMEHYLPARVMEKLDLSYIKEELPKLHNTYVGASEKETELEFLKVCQRLTEYGVHF 780
            VSYFRMEHYLPARVMEKLDLSYIKEELPKLHNTYVGASEKETELEFLKVCQRLTEYGVHF
Sbjct: 721  VSYFRMEHYLPARVMEKLDLSYIKEELPKLHNTYVGASEKETELEFLKVCQRLTEYGVHF 780

Query: 781  HRVHPEKKSQTGILLGVCSKGVLVFEVHNGVRTLVLRFPWRETKKISFSKKKITLQNTSD 840
            HRVHPEKKSQTGILLGVCSKGVLVFEVHNGVRTLVLRFPWRETKKISFSKKKITLQNTSD
Sbjct: 781  HRVHPEKKSQTGILLGVCSKGVLVFEVHNGVRTLVLRFPWRETKKISFSKKKITLQNTSD 840

Query: 841  GIKHGFQTDNSKICQYLLHLCSYQHKFQLQMRARQSNQDAQDIERASFRSLNLQAESVRG 900
            GIKHGFQTDNSKICQYLLHLCSYQHKFQLQMRARQSNQDAQDIERASFRSLNLQAESVRG
Sbjct: 841  GIKHGFQTDNSKICQYLLHLCSYQHKFQLQMRARQSNQDAQDIERASFRSLNLQAESVRG 900

Query: 901  FNMGRAISTGSLASSTLNKLAVRPLSVQAEILKRLSCSELSLYQPLQNSSKEKNDKASWE 960
            FNMGRAISTGSLASSTLNKLAVRPLSVQAEILKRLSCSELSLYQPLQNSSKEKNDKASWE
Sbjct: 901  FNMGRAISTGSLASSTLNKLAVRPLSVQAEILKRLSCSELSLYQPLQNSSKEKNDKASWE 960

Query: 961  EKPREMSKSYHDLSQASLYPHRKNVIVNMEPPPQTVAELVGKPSHQMSRSDAESLAGVTK 1020
            EKPREMSKSYHDLSQASLYPHRKNVIVNMEPPPQTVAELVGKPSHQMSRSDAESLAGVTK
Sbjct: 961  EKPREMSKSYHDLSQASLYPHRKNVIVNMEPPPQTVAELVGKPSHQMSRSDAESLAGVTK 1020

Query: 1021 LNNSKSVASLNRSPERRKHESDSSSIEDPGQAYVLGMTMHSSGNSSSQVPLKENDVLHKR 1080
            LNNSKSVASLNRSPERRKHESDSSSIEDPGQAYVLGMTMHSSGNSSSQVPLKENDVLHKR
Sbjct: 1021 LNNSKSVASLNRSPERRKHESDSSSIEDPGQAYVLGMTMHSSGNSSSQVPLKENDVLHKR 1080

Query: 1081 WSIVSSPEREITLVNLKKDAKYGLGFQIIGGEKMGRLDLGIFISSVAPGGPADLDGCLKP 1140
            WSIVSSPEREITLVNLKKDAKYGLGFQIIGGEKMGRLDLGIFISSVAPGGPADLDGCLKP
Sbjct: 1081 WSIVSSPEREITLVNLKKDAKYGLGFQIIGGEKMGRLDLGIFISSVAPGGPADLDGCLKP 1140

Query: 1141 GDRLISVNSVSLEGVSHHAAIEILQNAPEDVTLVISQPKEKISKVPSTPVHLTNEMKNYM 1200
            GDRLISVNSVSLEGVSHHAAIEILQNAPEDVTLVISQPKEKISKVPSTPVHLTNEMKNYM
Sbjct: 1141 GDRLISVNSVSLEGVSHHAAIEILQNAPEDVTLVISQPKEKISKVPSTPVHLTNEMKNYM 1200

Query: 1201 KKSSYMQDSAIDSSSKDHHWSRGTLRHISENSFGPSGGLREGSLSSQDSRTESASLSQSQ 1260
            KKSSYMQDSAIDSSSKDHHWSRGTLRHISENSFGPSGGLREGSLSSQDSRTESASLSQSQ
Sbjct: 1201 KKSSYMQDSAIDSSSKDHHWSRGTLRHISENSFGPSGGLREGSLSSQDSRTESASLSQSQ 1260

Query: 1261 VNGFFASHLGDQTWQESQHGSPSPSVISKATEKETFTDSNQSKTKKPGISDVTDYSDRGD 1320
            VNGFFASHLGDQTWQESQHGSPSPSVISKATEKETFTDSNQSKTKKPGISDVTDYSDRGD
Sbjct: 1261 VNGFFASHLGDQTWQESQHGSPSPSVISKATEKETFTDSNQSKTKKPGISDVTDYSDRGD 1320

Query: 1321 SDMDEATYSSSQDHQTPKQESSSSVNTSNKMNFKTFSSSPPKPGDIFEVELAKNDNSLGI 1380
            SDMDEATYSSSQDHQTPKQESSSSVNTSNKMNFKTFSSSPPKPGDIFEVELAKNDNSLGI
Sbjct: 1321 SDMDEATYSSSQDHQTPKQESSSSVNTSNKMNFKTFSSSPPKPGDIFEVELAKNDNSLGI 1380

Query: 1381 SVT-----GGVNTSVRHGGIYVKAVIPQGAAESDGRIHKGDRVLAVNGVSLEGATHKQAV 1435
            SVT     GGVNTSVRHGGIYVKAVIPQGAAESDGRIHKGDRVLAVNGVSLEGATHKQAV
Sbjct: 1381 SVTVLFDKGGVNTSVRHGGIYVKAVIPQGAAESDGRIHKGDRVLAVNGVSLEGATHKQAV 1440

Query: 1436 ETLRNTGQVVHLLLEKGQSPTSKEHVPVTPQCTLSDQNAQGQGPEKVKKTTQVKDYSFVT 1495
            ETLRNTGQVVHLLLEKGQSPTSKEHVPVTPQCTLSDQNAQGQGPEKVKKTTQVKDYSFVT
Sbjct: 1441 ETLRNTGQVVHLLLEKGQSPTSKEHVPVTPQCTLSDQNAQGQGPEKVKKTTQVKDYSFVT 1500

Query: 1496 EENTFEVKLFKNSSGLGFSFSREDNLIPEQINASIVRVKKLFPGQPAAESGKIDVGDVIL 1555
            EENTFEVKLFKNSSGLGFSFSREDNLIPEQINASIVRVKKLFPGQPAAESGKIDVGDVIL
Sbjct: 1501 EENTFEVKLFKNSSGLGFSFSREDNLIPEQINASIVRVKKLFPGQPAAESGKIDVGDVIL 1560

Query: 1556 KVNGASLKGLSQQEVISALRGTAPEVFLLLCRPPPGVLPEIDTALLTPLQSPAQVLPNSS 1615
            KVNGASLKGLSQQEVISALRGTAPEVFLLLCRPPPGVLPEIDTALLTPLQSPAQVLPNSS
Sbjct: 1561 KVNGASLKGLSQQEVISALRGTAPEVFLLLCRPPPGVLPEIDTALLTPLQSPAQVLPNSS 1620

Query: 1616 KDSSQPSCVEQSTSSDENEMSDKSKKQCKSPSRRDSYSDSSGSGEDDLVTAPANISNSTW 1675
            KDSSQPSCVEQSTSSDENEMSDKSKKQCKSPSRRDSYSDSSGSGEDDLVTAPANISNSTW
Sbjct: 1621 KDSSQPSCVEQSTSSDENEMSDKSKKQCKSPSRRDSYSDSSGSGEDDLVTAPANISNSTW 1680

Query: 1676 SSALHQTLSNMVSQAQSHHEAPKSQEDTICTMFYYPQKIPNKPEFEDSNPSPLPPDMAPG 1735
            SSALHQTLSNMVSQAQSHHEAPKSQEDTICTMFYYPQKIPNKPEFEDSNPSPLPPDMAPG
Sbjct: 1681 SSALHQTLSNMVSQAQSHHEAPKSQEDTICTMFYYPQKIPNKPEFEDSNPSPLPPDMAPG 1740

Query: 1736 QSYQPQSESASSSSMDKYHIHHISEPTRQENWTPLKNDLENHLEDFELEVELLITLIKSE 1795
            QSYQPQSESASSSSMDKYHIHHISEPTRQENWTPLKNDLENHLEDFELEVELLITLIKSE
Sbjct: 1741 QSYQPQSESASSSSMDKYHIHHISEPTRQENWTPLKNDLENHLEDFELEVELLITLIKSE 1800

Query: 1796 KGSLGFTVTKGNQRIGCYVHDVIQDPAKSDGRLKPGDRLIKVNDTDVTNMTHTDAVNLLR 1855
            KGSLGFTVTKGNQRIGCYVHDVIQDPAKSDGRLKPGDRLIKVNDTDVTNMTHTDAVNLLR
Sbjct: 1801 KGSLGFTVTKGNQRIGCYVHDVIQDPAKSDGRLKPGDRLIKVNDTDVTNMTHTDAVNLLR 1860

Query: 1856 AASKTVRLVIGRVLELPRIPMLPHLLPDITLTCNKEELGFSLCGGHDSLYQVVYISDINP 1915
            AASKTVRLVIGRVLELPRIPMLPHLLPDITLTCNKEELGFSLCGGHDSLYQVVYISDINP
Sbjct: 1861 AASKTVRLVIGRVLELPRIPMLPHLLPDITLTCNKEELGFSLCGGHDSLYQVVYISDINP 1920

Query: 1916 RSVAAIEGNLQLLDVIHYVNGVSTQGMTLEEVNRALDMSLPSLVLKATRNDLPVVPSSKR 1975
            RSVAAIEGNLQLLDVIHYVNGVSTQGMTLEEVNRALDMSLPSLVLKATRNDLPVVPSSKR
Sbjct: 1921 RSVAAIEGNLQLLDVIHYVNGVSTQGMTLEEVNRALDMSLPSLVLKATRNDLPVVPSSKR 1980

Query: 1976 SAVSAPKSTKGNGSYSVGSCSQPALTPNDSFSTVAGEEINEISYPKGKCSTYQIKGSPNL 2035
            SAVSAPKSTKGNGSYSVGSCSQPALTPNDSFSTVAGEEINEISYPKGKCSTYQIKGSPNL
Sbjct: 1981 SAVSAPKSTKGNGSYSVGSCSQPALTPNDSFSTVAGEEINEISYPKGKCSTYQIKGSPNL 2040

Query: 2036 TLPKESYIQEDDIYDDSQEAEVIQSLLDVVDEEAQNLLNENNAAGYSCGPGTLKMNGKLS 2095
            TLPKESYIQEDDIYDDSQEAEVIQSLLDVVDEEAQNLLNENNAAGYSCGPGTLKMNGKLS
Sbjct: 2041 TLPKESYIQEDDIYDDSQEAEVIQSLLDVVDEEAQNLLNENNAAGYSCGPGTLKMNGKLS 2100

Query: 2096 EERTEDTDCDGSPLPEYFTEATKMNGCEEYCEEKVKSESLIQKPQEKKTDDDEITWGNDE 2155
            EERTEDTDCDGSPLPEYFTEATKMNGCEEYCEEKVKSESLIQKPQEKKTDDDEITWGNDE
Sbjct: 2101 EERTEDTDCDGSPLPEYFTEATKMNGCEEYCEEKVKSESLIQKPQEKKTDDDEITWGNDE 2160

Query: 2156 LPIERTNHEDSDKDHSFLTNDELAVLPVVKVLPSGKYTGANLKSVIRVLRGLLDQGIPSK 2215
            LPIERTNHEDSDKDHSFLTNDELAVLPVVKVLPSGKYTGANLKSVIRVLRGLLDQGIPSK
Sbjct: 2161 LPIERTNHEDSDKDHSFLTNDELAVLPVVKVLPSGKYTGANLKSVIRVLRGLLDQGIPSK 2220

Query: 2216 ELENLQELKPLDQCLIGQTKENRRKNRYKNILPYDATRVPLGDEGGYINASFIKIPVGKE 2275
            ELENLQELKPLDQCLIGQTKENRRKNRYKNILPYDATRVPLGDEGGYINASFIKIPVGKE
Sbjct: 2221 ELENLQELKPLDQCLIGQTKENRRKNRYKNILPYDATRVPLGDEGGYINASFIKIPVGKE 2280

Query: 2276 EFVYIACQGPLPTTVGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSN 2335
            EFVYIACQGPLPTTVGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSN
Sbjct: 2281 EFVYIACQGPLPTTVGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSN 2340

Query: 2336 RLRLALVRMQQLKGFVVRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYM 2395
            RLRLALVRMQQLKGFVVRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYM
Sbjct: 2341 RLRLALVRMQQLKGFVVRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYM 2400

Query: 2396 RHIHRSGPIITHCSAGIGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTED 2455
            RHIHRSGPIITHCSAGIGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTED
Sbjct: 2401 RHIHRSGPIITHCSAGIGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTED 2460

Query: 2456 QYIFCYQVILYVLTRLQAEEEQKQQPQLLK 2485
            QYIFCYQVILYVLTRLQAEEEQKQQPQLLK
Sbjct: 2461 QYIFCYQVILYVLTRLQAEEEQKQQPQLLK 2490


>gi|5453992 protein tyrosine phosphatase, non-receptor type 13 isoform
            2 [Homo sapiens]
          Length = 2466

 Score = 4892 bits (12689), Expect = 0.0
 Identities = 2466/2485 (99%), Positives = 2466/2485 (99%), Gaps = 19/2485 (0%)

Query: 1    MHVSLAEALEVRGGPLQEEEIWAVLNQSAESLQELFRKVSLADPAALGFIISPWSLLLLP 60
            MHVSLAEALEVRGGPLQEEEIWAVLNQSAESLQELFRKVSLADPAALGFIISPWSLLLLP
Sbjct: 1    MHVSLAEALEVRGGPLQEEEIWAVLNQSAESLQELFRKVSLADPAALGFIISPWSLLLLP 60

Query: 61   SGSVSFTDENISNQDLRAFTAPEVLQNQSLTSLSDVEKIHIYSLGMTLYWGADYEVPQSQ 120
            SGSVSFTDENISNQDLRAFTAPEVLQNQSLTSLSDVEKIHIYSLGMTLYWGADYEVPQSQ
Sbjct: 61   SGSVSFTDENISNQDLRAFTAPEVLQNQSLTSLSDVEKIHIYSLGMTLYWGADYEVPQSQ 120

Query: 121  PIKLGDHLNSILLGMCEDVIYARVSVRTVLDACSAHIRNSNCAPSFSYVKHLVKLVLGNL 180
            PIKLGDHLNSILLGMCEDVIYARVSVRTVLDACSAHIRNSNCAPSFSYVKHLVKLVLGNL
Sbjct: 121  PIKLGDHLNSILLGMCEDVIYARVSVRTVLDACSAHIRNSNCAPSFSYVKHLVKLVLGNL 180

Query: 181  SGTDQLSCNSEQKPDRSQAIRDRLRGKGLPTGRSSTSDVLDIQKPPLSHQTFLNKGLSKS 240
            SGTDQLSCNSEQKPDRSQAIRDRLRGKGLPTGRSSTSDVLDIQKPPLSHQTFLNKGLSKS
Sbjct: 181  SGTDQLSCNSEQKPDRSQAIRDRLRGKGLPTGRSSTSDVLDIQKPPLSHQTFLNKGLSKS 240

Query: 241  MGFLSIKDTQDENYFKDILSDNSGREDSENTFSPYQFKTSGPEKKPIPGIDVLSKKKIWA 300
            MGFLSIKDTQDENYFKDILSDNSGREDSENTFSPYQFKTSGPEKKPIPGIDVLSKKKIWA
Sbjct: 241  MGFLSIKDTQDENYFKDILSDNSGREDSENTFSPYQFKTSGPEKKPIPGIDVLSKKKIWA 300

Query: 301  SSMDLLCTADRDFSSGETATYRRCHPEAVTVRTSTTPRKKEARYSDGSIALDIFGPQKMD 360
            SSMDLLCTADRDFSSGETATYRRCHPEAVTVRTSTTPRKKEARYSDGSIALDIFGPQKMD
Sbjct: 301  SSMDLLCTADRDFSSGETATYRRCHPEAVTVRTSTTPRKKEARYSDGSIALDIFGPQKMD 360

Query: 361  PIYHTRELPTSSAISSALDRIRERQKKLQVLREAMNVEEPVRRYKTYHGDVFSTSSESPS 420
            PIYHTRELPTSSAISSALDRIRERQKKLQVLREAMNVEEPVRRYKTYHGDVFSTSSESPS
Sbjct: 361  PIYHTRELPTSSAISSALDRIRERQKKLQVLREAMNVEEPVRRYKTYHGDVFSTSSESPS 420

Query: 421  IISSESDFRQVRRSEASKRFESSSGLPGVDETLSQGQSQRPSRQYETPFEGNLINQEIML 480
            IISSESDFRQVRRSEASKRFESSSGLPGVDETLSQGQSQRPSRQYETPFEGNLINQEIML
Sbjct: 421  IISSESDFRQVRRSEASKRFESSSGLPGVDETLSQGQSQRPSRQYETPFEGNLINQEIML 480

Query: 481  KRQEEELMQLQAKMALRQSRLSLYPGDTIKASMLDITRDPLREIALETAMTQRKLRNFFG 540
            KRQEEELMQLQAKMALRQSRLSLYPGDTIKASMLDITRDPLREIALETAMTQRKLRNFFG
Sbjct: 481  KRQEEELMQLQAKMALRQSRLSLYPGDTIKASMLDITRDPLREIALETAMTQRKLRNFFG 540

Query: 541  PEFVKMTIEPFISLDLPRSILTKKGKNEDNRRKVNIMLLNGQRLELTCDTKTICKDVFDM 600
            PEFVKMTIEPFISLDLPRSILTKKGKNEDNRRKVNIMLLNGQRLELTCDTKTICKDVFDM
Sbjct: 541  PEFVKMTIEPFISLDLPRSILTKKGKNEDNRRKVNIMLLNGQRLELTCDTKTICKDVFDM 600

Query: 601  VVAHIGLVEHHLFALATLKDNEYFFVDPDLKLTKVAPEGWKEEPKKKTKATVNFTLFFRI 660
            VVAHIGLVEHHLFALATLKDNEYFFVDPDLKLTKVAPEGWKEEPKKKTKATVNFTLFFRI
Sbjct: 601  VVAHIGLVEHHLFALATLKDNEYFFVDPDLKLTKVAPEGWKEEPKKKTKATVNFTLFFRI 660

Query: 661  KFFMDDVSLIQHTLTCHQYYLQLRKDILEERMHCDDETSLLLASLALQAEYGDYQPEVHG 720
            KFFMDDVSLIQHTLTCHQYYLQLRKDILEERMHCDDETSLLLASLALQAEYGDYQPEVHG
Sbjct: 661  KFFMDDVSLIQHTLTCHQYYLQLRKDILEERMHCDDETSLLLASLALQAEYGDYQPEVHG 720

Query: 721  VSYFRMEHYLPARVMEKLDLSYIKEELPKLHNTYVGASEKETELEFLKVCQRLTEYGVHF 780
            VSYFRMEHYLPARVMEKLDLSYIKEELPKLHNTYVGASEKETELEFLKVCQRLTEYGVHF
Sbjct: 721  VSYFRMEHYLPARVMEKLDLSYIKEELPKLHNTYVGASEKETELEFLKVCQRLTEYGVHF 780

Query: 781  HRVHPEKKSQTGILLGVCSKGVLVFEVHNGVRTLVLRFPWRETKKISFSKKKITLQNTSD 840
            HRVHPEKKSQTGILLGVCSKGVLVFEVHNGVRTLVLRFPWRETKKISFSKKKITLQNTSD
Sbjct: 781  HRVHPEKKSQTGILLGVCSKGVLVFEVHNGVRTLVLRFPWRETKKISFSKKKITLQNTSD 840

Query: 841  GIKHGFQTDNSKICQYLLHLCSYQHKFQLQMRARQSNQDAQDIERASFRSLNLQAESVRG 900
            GIKHGFQTDNSKICQYLLHLCSYQHKFQLQMRARQSNQDAQDIERASFRSLNLQAESVRG
Sbjct: 841  GIKHGFQTDNSKICQYLLHLCSYQHKFQLQMRARQSNQDAQDIERASFRSLNLQAESVRG 900

Query: 901  FNMGRAISTGSLASSTLNKLAVRPLSVQAEILKRLSCSELSLYQPLQNSSKEKNDKASWE 960
            FNMGRAISTGSLASSTLNKLAVRPLSVQAEILKRLSCSELSLYQPLQNSSKEKNDKASWE
Sbjct: 901  FNMGRAISTGSLASSTLNKLAVRPLSVQAEILKRLSCSELSLYQPLQNSSKEKNDKASWE 960

Query: 961  EKPREMSKSYHDLSQASLYPHRKNVIVNMEPPPQTVAELVGKPSHQMSRSDAESLAGVTK 1020
            EKPREMSKSYHDLSQASLYPHRKNVIVNMEPPPQTVAELVGKPSHQMSRSDAESLAGVTK
Sbjct: 961  EKPREMSKSYHDLSQASLYPHRKNVIVNMEPPPQTVAELVGKPSHQMSRSDAESLAGVTK 1020

Query: 1021 LNNSKSVASLNRSPERRKHESDSSSIEDPGQAYVLGMTMHSSGNSSSQVPLKENDVLHKR 1080
            LNNSKSVASLNRSPERRKHESDSSSIEDPGQAYVL                   DVLHKR
Sbjct: 1021 LNNSKSVASLNRSPERRKHESDSSSIEDPGQAYVL-------------------DVLHKR 1061

Query: 1081 WSIVSSPEREITLVNLKKDAKYGLGFQIIGGEKMGRLDLGIFISSVAPGGPADLDGCLKP 1140
            WSIVSSPEREITLVNLKKDAKYGLGFQIIGGEKMGRLDLGIFISSVAPGGPADLDGCLKP
Sbjct: 1062 WSIVSSPEREITLVNLKKDAKYGLGFQIIGGEKMGRLDLGIFISSVAPGGPADLDGCLKP 1121

Query: 1141 GDRLISVNSVSLEGVSHHAAIEILQNAPEDVTLVISQPKEKISKVPSTPVHLTNEMKNYM 1200
            GDRLISVNSVSLEGVSHHAAIEILQNAPEDVTLVISQPKEKISKVPSTPVHLTNEMKNYM
Sbjct: 1122 GDRLISVNSVSLEGVSHHAAIEILQNAPEDVTLVISQPKEKISKVPSTPVHLTNEMKNYM 1181

Query: 1201 KKSSYMQDSAIDSSSKDHHWSRGTLRHISENSFGPSGGLREGSLSSQDSRTESASLSQSQ 1260
            KKSSYMQDSAIDSSSKDHHWSRGTLRHISENSFGPSGGLREGSLSSQDSRTESASLSQSQ
Sbjct: 1182 KKSSYMQDSAIDSSSKDHHWSRGTLRHISENSFGPSGGLREGSLSSQDSRTESASLSQSQ 1241

Query: 1261 VNGFFASHLGDQTWQESQHGSPSPSVISKATEKETFTDSNQSKTKKPGISDVTDYSDRGD 1320
            VNGFFASHLGDQTWQESQHGSPSPSVISKATEKETFTDSNQSKTKKPGISDVTDYSDRGD
Sbjct: 1242 VNGFFASHLGDQTWQESQHGSPSPSVISKATEKETFTDSNQSKTKKPGISDVTDYSDRGD 1301

Query: 1321 SDMDEATYSSSQDHQTPKQESSSSVNTSNKMNFKTFSSSPPKPGDIFEVELAKNDNSLGI 1380
            SDMDEATYSSSQDHQTPKQESSSSVNTSNKMNFKTFSSSPPKPGDIFEVELAKNDNSLGI
Sbjct: 1302 SDMDEATYSSSQDHQTPKQESSSSVNTSNKMNFKTFSSSPPKPGDIFEVELAKNDNSLGI 1361

Query: 1381 SVTGGVNTSVRHGGIYVKAVIPQGAAESDGRIHKGDRVLAVNGVSLEGATHKQAVETLRN 1440
            SVTGGVNTSVRHGGIYVKAVIPQGAAESDGRIHKGDRVLAVNGVSLEGATHKQAVETLRN
Sbjct: 1362 SVTGGVNTSVRHGGIYVKAVIPQGAAESDGRIHKGDRVLAVNGVSLEGATHKQAVETLRN 1421

Query: 1441 TGQVVHLLLEKGQSPTSKEHVPVTPQCTLSDQNAQGQGPEKVKKTTQVKDYSFVTEENTF 1500
            TGQVVHLLLEKGQSPTSKEHVPVTPQCTLSDQNAQGQGPEKVKKTTQVKDYSFVTEENTF
Sbjct: 1422 TGQVVHLLLEKGQSPTSKEHVPVTPQCTLSDQNAQGQGPEKVKKTTQVKDYSFVTEENTF 1481

Query: 1501 EVKLFKNSSGLGFSFSREDNLIPEQINASIVRVKKLFPGQPAAESGKIDVGDVILKVNGA 1560
            EVKLFKNSSGLGFSFSREDNLIPEQINASIVRVKKLFPGQPAAESGKIDVGDVILKVNGA
Sbjct: 1482 EVKLFKNSSGLGFSFSREDNLIPEQINASIVRVKKLFPGQPAAESGKIDVGDVILKVNGA 1541

Query: 1561 SLKGLSQQEVISALRGTAPEVFLLLCRPPPGVLPEIDTALLTPLQSPAQVLPNSSKDSSQ 1620
            SLKGLSQQEVISALRGTAPEVFLLLCRPPPGVLPEIDTALLTPLQSPAQVLPNSSKDSSQ
Sbjct: 1542 SLKGLSQQEVISALRGTAPEVFLLLCRPPPGVLPEIDTALLTPLQSPAQVLPNSSKDSSQ 1601

Query: 1621 PSCVEQSTSSDENEMSDKSKKQCKSPSRRDSYSDSSGSGEDDLVTAPANISNSTWSSALH 1680
            PSCVEQSTSSDENEMSDKSKKQCKSPSRRDSYSDSSGSGEDDLVTAPANISNSTWSSALH
Sbjct: 1602 PSCVEQSTSSDENEMSDKSKKQCKSPSRRDSYSDSSGSGEDDLVTAPANISNSTWSSALH 1661

Query: 1681 QTLSNMVSQAQSHHEAPKSQEDTICTMFYYPQKIPNKPEFEDSNPSPLPPDMAPGQSYQP 1740
            QTLSNMVSQAQSHHEAPKSQEDTICTMFYYPQKIPNKPEFEDSNPSPLPPDMAPGQSYQP
Sbjct: 1662 QTLSNMVSQAQSHHEAPKSQEDTICTMFYYPQKIPNKPEFEDSNPSPLPPDMAPGQSYQP 1721

Query: 1741 QSESASSSSMDKYHIHHISEPTRQENWTPLKNDLENHLEDFELEVELLITLIKSEKGSLG 1800
            QSESASSSSMDKYHIHHISEPTRQENWTPLKNDLENHLEDFELEVELLITLIKSEKGSLG
Sbjct: 1722 QSESASSSSMDKYHIHHISEPTRQENWTPLKNDLENHLEDFELEVELLITLIKSEKGSLG 1781

Query: 1801 FTVTKGNQRIGCYVHDVIQDPAKSDGRLKPGDRLIKVNDTDVTNMTHTDAVNLLRAASKT 1860
            FTVTKGNQRIGCYVHDVIQDPAKSDGRLKPGDRLIKVNDTDVTNMTHTDAVNLLRAASKT
Sbjct: 1782 FTVTKGNQRIGCYVHDVIQDPAKSDGRLKPGDRLIKVNDTDVTNMTHTDAVNLLRAASKT 1841

Query: 1861 VRLVIGRVLELPRIPMLPHLLPDITLTCNKEELGFSLCGGHDSLYQVVYISDINPRSVAA 1920
            VRLVIGRVLELPRIPMLPHLLPDITLTCNKEELGFSLCGGHDSLYQVVYISDINPRSVAA
Sbjct: 1842 VRLVIGRVLELPRIPMLPHLLPDITLTCNKEELGFSLCGGHDSLYQVVYISDINPRSVAA 1901

Query: 1921 IEGNLQLLDVIHYVNGVSTQGMTLEEVNRALDMSLPSLVLKATRNDLPVVPSSKRSAVSA 1980
            IEGNLQLLDVIHYVNGVSTQGMTLEEVNRALDMSLPSLVLKATRNDLPVVPSSKRSAVSA
Sbjct: 1902 IEGNLQLLDVIHYVNGVSTQGMTLEEVNRALDMSLPSLVLKATRNDLPVVPSSKRSAVSA 1961

Query: 1981 PKSTKGNGSYSVGSCSQPALTPNDSFSTVAGEEINEISYPKGKCSTYQIKGSPNLTLPKE 2040
            PKSTKGNGSYSVGSCSQPALTPNDSFSTVAGEEINEISYPKGKCSTYQIKGSPNLTLPKE
Sbjct: 1962 PKSTKGNGSYSVGSCSQPALTPNDSFSTVAGEEINEISYPKGKCSTYQIKGSPNLTLPKE 2021

Query: 2041 SYIQEDDIYDDSQEAEVIQSLLDVVDEEAQNLLNENNAAGYSCGPGTLKMNGKLSEERTE 2100
            SYIQEDDIYDDSQEAEVIQSLLDVVDEEAQNLLNENNAAGYSCGPGTLKMNGKLSEERTE
Sbjct: 2022 SYIQEDDIYDDSQEAEVIQSLLDVVDEEAQNLLNENNAAGYSCGPGTLKMNGKLSEERTE 2081

Query: 2101 DTDCDGSPLPEYFTEATKMNGCEEYCEEKVKSESLIQKPQEKKTDDDEITWGNDELPIER 2160
            DTDCDGSPLPEYFTEATKMNGCEEYCEEKVKSESLIQKPQEKKTDDDEITWGNDELPIER
Sbjct: 2082 DTDCDGSPLPEYFTEATKMNGCEEYCEEKVKSESLIQKPQEKKTDDDEITWGNDELPIER 2141

Query: 2161 TNHEDSDKDHSFLTNDELAVLPVVKVLPSGKYTGANLKSVIRVLRGLLDQGIPSKELENL 2220
            TNHEDSDKDHSFLTNDELAVLPVVKVLPSGKYTGANLKSVIRVLRGLLDQGIPSKELENL
Sbjct: 2142 TNHEDSDKDHSFLTNDELAVLPVVKVLPSGKYTGANLKSVIRVLRGLLDQGIPSKELENL 2201

Query: 2221 QELKPLDQCLIGQTKENRRKNRYKNILPYDATRVPLGDEGGYINASFIKIPVGKEEFVYI 2280
            QELKPLDQCLIGQTKENRRKNRYKNILPYDATRVPLGDEGGYINASFIKIPVGKEEFVYI
Sbjct: 2202 QELKPLDQCLIGQTKENRRKNRYKNILPYDATRVPLGDEGGYINASFIKIPVGKEEFVYI 2261

Query: 2281 ACQGPLPTTVGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSNRLRLA 2340
            ACQGPLPTTVGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSNRLRLA
Sbjct: 2262 ACQGPLPTTVGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSNRLRLA 2321

Query: 2341 LVRMQQLKGFVVRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYMRHIHR 2400
            LVRMQQLKGFVVRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYMRHIHR
Sbjct: 2322 LVRMQQLKGFVVRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYMRHIHR 2381

Query: 2401 SGPIITHCSAGIGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTEDQYIFC 2460
            SGPIITHCSAGIGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTEDQYIFC
Sbjct: 2382 SGPIITHCSAGIGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTEDQYIFC 2441

Query: 2461 YQVILYVLTRLQAEEEQKQQPQLLK 2485
            YQVILYVLTRLQAEEEQKQQPQLLK
Sbjct: 2442 YQVILYVLTRLQAEEEQKQQPQLLK 2466


>gi|18375648 protein tyrosine phosphatase, non-receptor type 13
            isoform 3 [Homo sapiens]
          Length = 2294

 Score = 2820 bits (7310), Expect = 0.0
 Identities = 1423/1475 (96%), Positives = 1434/1475 (97%), Gaps = 14/1475 (0%)

Query: 1020 KLNNSKSVASLNRSPERRKH--ESDSSSIEDP-------GQAYVLGMTMHSSGNSSSQVP 1070
            K++ SK   +L  + +  KH  ++D+S I             + L M    S   +  + 
Sbjct: 825  KISFSKKKITLQNTSDGIKHGFQTDNSKICQYLLHLCSYQHKFQLQMRARQSNQDAQDI- 883

Query: 1071 LKENDVLHKRWSIVSSPEREITLVNLKKDAKYGLGFQIIGGEKMGRLDLGIFISSVAPGG 1130
                DVLHKRWSIVSSPEREITLVNLKKDAKYGLGFQIIGGEKMGRLDLGIFISSVAPGG
Sbjct: 884  ----DVLHKRWSIVSSPEREITLVNLKKDAKYGLGFQIIGGEKMGRLDLGIFISSVAPGG 939

Query: 1131 PADLDGCLKPGDRLISVNSVSLEGVSHHAAIEILQNAPEDVTLVISQPKEKISKVPSTPV 1190
            PADLDGCLKPGDRLISVNSVSLEGVSHHAAIEILQNAPEDVTLVISQPKEKISKVPSTPV
Sbjct: 940  PADLDGCLKPGDRLISVNSVSLEGVSHHAAIEILQNAPEDVTLVISQPKEKISKVPSTPV 999

Query: 1191 HLTNEMKNYMKKSSYMQDSAIDSSSKDHHWSRGTLRHISENSFGPSGGLREGSLSSQDSR 1250
            HLTNEMKNYMKKSSYMQDSAIDSSSKDHHWSRGTLRHISENSFGPSGGLREGSLSSQDSR
Sbjct: 1000 HLTNEMKNYMKKSSYMQDSAIDSSSKDHHWSRGTLRHISENSFGPSGGLREGSLSSQDSR 1059

Query: 1251 TESASLSQSQVNGFFASHLGDQTWQESQHGSPSPSVISKATEKETFTDSNQSKTKKPGIS 1310
            TESASLSQSQVNGFFASHLGDQTWQESQHGSPSPSVISKATEKETFTDSNQSKTKKPGIS
Sbjct: 1060 TESASLSQSQVNGFFASHLGDQTWQESQHGSPSPSVISKATEKETFTDSNQSKTKKPGIS 1119

Query: 1311 DVTDYSDRGDSDMDEATYSSSQDHQTPKQESSSSVNTSNKMNFKTFSSSPPKPGDIFEVE 1370
            DVTDYSDRGDSDMDEATYSSSQDHQTPKQESSSSVNTSNKMNFKTFSSSPPKPGDIFEVE
Sbjct: 1120 DVTDYSDRGDSDMDEATYSSSQDHQTPKQESSSSVNTSNKMNFKTFSSSPPKPGDIFEVE 1179

Query: 1371 LAKNDNSLGISVTGGVNTSVRHGGIYVKAVIPQGAAESDGRIHKGDRVLAVNGVSLEGAT 1430
            LAKNDNSLGISVTGGVNTSVRHGGIYVKAVIPQGAAESDGRIHKGDRVLAVNGVSLEGAT
Sbjct: 1180 LAKNDNSLGISVTGGVNTSVRHGGIYVKAVIPQGAAESDGRIHKGDRVLAVNGVSLEGAT 1239

Query: 1431 HKQAVETLRNTGQVVHLLLEKGQSPTSKEHVPVTPQCTLSDQNAQGQGPEKVKKTTQVKD 1490
            HKQAVETLRNTGQVVHLLLEKGQSPTSKEHVPVTPQCTLSDQNAQGQGPEKVKKTTQVKD
Sbjct: 1240 HKQAVETLRNTGQVVHLLLEKGQSPTSKEHVPVTPQCTLSDQNAQGQGPEKVKKTTQVKD 1299

Query: 1491 YSFVTEENTFEVKLFKNSSGLGFSFSREDNLIPEQINASIVRVKKLFPGQPAAESGKIDV 1550
            YSFVTEENTFEVKLFKNSSGLGFSFSREDNLIPEQINASIVRVKKLFPGQPAAESGKIDV
Sbjct: 1300 YSFVTEENTFEVKLFKNSSGLGFSFSREDNLIPEQINASIVRVKKLFPGQPAAESGKIDV 1359

Query: 1551 GDVILKVNGASLKGLSQQEVISALRGTAPEVFLLLCRPPPGVLPEIDTALLTPLQSPAQV 1610
            GDVILKVNGASLKGLSQQEVISALRGTAPEVFLLLCRPPPGVLPEIDTALLTPLQSPAQV
Sbjct: 1360 GDVILKVNGASLKGLSQQEVISALRGTAPEVFLLLCRPPPGVLPEIDTALLTPLQSPAQV 1419

Query: 1611 LPNSSKDSSQPSCVEQSTSSDENEMSDKSKKQCKSPSRRDSYSDSSGSGEDDLVTAPANI 1670
            LPNSSKDSSQPSCVEQSTSSDENEMSDKSKKQCKSPSRRDSYSDSSGSGEDDLVTAPANI
Sbjct: 1420 LPNSSKDSSQPSCVEQSTSSDENEMSDKSKKQCKSPSRRDSYSDSSGSGEDDLVTAPANI 1479

Query: 1671 SNSTWSSALHQTLSNMVSQAQSHHEAPKSQEDTICTMFYYPQKIPNKPEFEDSNPSPLPP 1730
            SNSTWSSALHQTLSNMVSQAQSHHEAPKSQEDTICTMFYYPQKIPNKPEFEDSNPSPLPP
Sbjct: 1480 SNSTWSSALHQTLSNMVSQAQSHHEAPKSQEDTICTMFYYPQKIPNKPEFEDSNPSPLPP 1539

Query: 1731 DMAPGQSYQPQSESASSSSMDKYHIHHISEPTRQENWTPLKNDLENHLEDFELEVELLIT 1790
            DMAPGQSYQPQSESASSSSMDKYHIHHISEPTRQENWTPLKNDLENHLEDFELEVELLIT
Sbjct: 1540 DMAPGQSYQPQSESASSSSMDKYHIHHISEPTRQENWTPLKNDLENHLEDFELEVELLIT 1599

Query: 1791 LIKSEKGSLGFTVTKGNQRIGCYVHDVIQDPAKSDGRLKPGDRLIKVNDTDVTNMTHTDA 1850
            LIKSEKGSLGFTVTKGNQRIGCYVHDVIQDPAKSDGRLKPGDRLIKVNDTDVTNMTHTDA
Sbjct: 1600 LIKSEKGSLGFTVTKGNQRIGCYVHDVIQDPAKSDGRLKPGDRLIKVNDTDVTNMTHTDA 1659

Query: 1851 VNLLRAASKTVRLVIGRVLELPRIPMLPHLLPDITLTCNKEELGFSLCGGHDSLYQVVYI 1910
            VNLLRAASKTVRLVIGRVLELPRIPMLPHLLPDITLTCNKEELGFSLCGGHDSLYQVVYI
Sbjct: 1660 VNLLRAASKTVRLVIGRVLELPRIPMLPHLLPDITLTCNKEELGFSLCGGHDSLYQVVYI 1719

Query: 1911 SDINPRSVAAIEGNLQLLDVIHYVNGVSTQGMTLEEVNRALDMSLPSLVLKATRNDLPVV 1970
            SDINPRSVAAIEGNLQLLDVIHYVNGVSTQGMTLEEVNRALDMSLPSLVLKATRNDLPVV
Sbjct: 1720 SDINPRSVAAIEGNLQLLDVIHYVNGVSTQGMTLEEVNRALDMSLPSLVLKATRNDLPVV 1779

Query: 1971 PSSKRSAVSAPKSTKGNGSYSVGSCSQPALTPNDSFSTVAGEEINEISYPKGKCSTYQIK 2030
            PSSKRSAVSAPKSTKGNGSYSVGSCSQPALTPNDSFSTVAGEEINEISYPKGKCSTYQIK
Sbjct: 1780 PSSKRSAVSAPKSTKGNGSYSVGSCSQPALTPNDSFSTVAGEEINEISYPKGKCSTYQIK 1839

Query: 2031 GSPNLTLPKESYIQEDDIYDDSQEAEVIQSLLDVVDEEAQNLLNENNAAGYSCGPGTLKM 2090
            GSPNLTLPKESYIQEDDIYDDSQEAEVIQSLLDVVDEEAQNLLNENNAAGYSCGPGTLKM
Sbjct: 1840 GSPNLTLPKESYIQEDDIYDDSQEAEVIQSLLDVVDEEAQNLLNENNAAGYSCGPGTLKM 1899

Query: 2091 NGKLSEERTEDTDCDGSPLPEYFTEATKMNGCEEYCEEKVKSESLIQKPQEKKTDDDEIT 2150
            NGKLSEERTEDTDCDGSPLPEYFTEATKMNGCEEYCEEKVKSESLIQKPQEKKTDDDEIT
Sbjct: 1900 NGKLSEERTEDTDCDGSPLPEYFTEATKMNGCEEYCEEKVKSESLIQKPQEKKTDDDEIT 1959

Query: 2151 WGNDELPIERTNHEDSDKDHSFLTNDELAVLPVVKVLPSGKYTGANLKSVIRVLRGLLDQ 2210
            WGNDELPIERTNHEDSDKDHSFLTNDELAVLPVVKVLPSGKYTGANLKSVIRVLRGLLDQ
Sbjct: 1960 WGNDELPIERTNHEDSDKDHSFLTNDELAVLPVVKVLPSGKYTGANLKSVIRVLRGLLDQ 2019

Query: 2211 GIPSKELENLQELKPLDQCLIGQTKENRRKNRYKNILPYDATRVPLGDEGGYINASFIKI 2270
            GIPSKELENLQELKPLDQCLIGQTKENRRKNRYKNILPYDATRVPLGDEGGYINASFIKI
Sbjct: 2020 GIPSKELENLQELKPLDQCLIGQTKENRRKNRYKNILPYDATRVPLGDEGGYINASFIKI 2079

Query: 2271 PVGKEEFVYIACQGPLPTTVGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKT 2330
            PVGKEEFVYIACQGPLPTTVGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKT
Sbjct: 2080 PVGKEEFVYIACQGPLPTTVGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKT 2139

Query: 2331 TMVSNRLRLALVRMQQLKGFVVRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLT 2390
            TMVSNRLRLALVRMQQLKGFVVRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLT
Sbjct: 2140 TMVSNRLRLALVRMQQLKGFVVRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLT 2199

Query: 2391 FISYMRHIHRSGPIITHCSAGIGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGM 2450
            FISYMRHIHRSGPIITHCSAGIGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGM
Sbjct: 2200 FISYMRHIHRSGPIITHCSAGIGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGM 2259

Query: 2451 VQTEDQYIFCYQVILYVLTRLQAEEEQKQQPQLLK 2485
            VQTEDQYIFCYQVILYVLTRLQAEEEQKQQPQLLK
Sbjct: 2260 VQTEDQYIFCYQVILYVLTRLQAEEEQKQQPQLLK 2294



 Score = 1805 bits (4675), Expect = 0.0
 Identities = 974/1280 (76%), Positives = 1035/1280 (80%), Gaps = 97/1280 (7%)

Query: 1    MHVSLAEALEVRGGPLQEEEIWAVLNQSAESLQELFRKVSLADPAALGFIISPWSLLLLP 60
            MHVSLAEALEVRGGPLQEEEIWAVLNQSAESLQELFRKVSLADPAALGFIISPWSLLLLP
Sbjct: 1    MHVSLAEALEVRGGPLQEEEIWAVLNQSAESLQELFRKVSLADPAALGFIISPWSLLLLP 60

Query: 61   SGSVSFTDENISNQDLRAFTAPEVLQNQSLTSLSDVEKIHIYSLGMTLYWGADYEVPQSQ 120
            SGSVSFTDENISNQDLRAFTAPEVLQNQSLTSLSDVEKIHIYSLGMTLYWGADYEVPQSQ
Sbjct: 61   SGSVSFTDENISNQDLRAFTAPEVLQNQSLTSLSDVEKIHIYSLGMTLYWGADYEVPQSQ 120

Query: 121  PIKLGDHLNSILLGMCEDVIYARVSVRTVLDACSAHIRNSNCAPSFSYVKHLVKLVLGNL 180
            PIKLGDHLNSILLGMCEDVIYARVSVRTVLDACSAHIRNSNCAPSFSYVKHLVKLVLGNL
Sbjct: 121  PIKLGDHLNSILLGMCEDVIYARVSVRTVLDACSAHIRNSNCAPSFSYVKHLVKLVLGNL 180

Query: 181  SGTDQLSCNSEQKPDRSQAIRDRLRGKGLPTGRSSTSDVLDIQKPPLSHQTFLNKGLSKS 240
            SGTDQLSCNSEQKPDRSQAIRDRLRGKGLPTGRSSTSDVLDIQKPPLSHQTFLNKGLSKS
Sbjct: 181  SGTDQLSCNSEQKPDRSQAIRDRLRGKGLPTGRSSTSDVLDIQKPPLSHQTFLNKGLSKS 240

Query: 241  MGFLSIKDTQDENYFKDILSDNSGREDSENTFSPYQFKTSGPEKKPIPGIDVLSKKKIWA 300
            MGFLSIKDTQDENYFKDILSDNSGREDSENTFSPYQFKTSGPEKKPIPGIDVLSKKKIWA
Sbjct: 241  MGFLSIKDTQDENYFKDILSDNSGREDSENTFSPYQFKTSGPEKKPIPGIDVLSKKKIWA 300

Query: 301  SSMDLLCTADRDFSSGETATYRRCHPEAVTVRTSTTPRKKEARYSDGSIALDIFGPQKMD 360
            SSMDLLCTADRDFSSGETATYRRCHPEAVTVRTSTTPRKKEARYSDGSIALDIFGPQKMD
Sbjct: 301  SSMDLLCTADRDFSSGETATYRRCHPEAVTVRTSTTPRKKEARYSDGSIALDIFGPQKMD 360

Query: 361  PIYHTRELPTSSAISSALDRIRERQKKLQVLREAMNVEEPVRRYKTYHGDVFSTSSESPS 420
            PIYHTRELPTSSAISSALDRIRERQKKLQVLREAMNVEEPVRRYKTYHGDVFSTSSESPS
Sbjct: 361  PIYHTRELPTSSAISSALDRIRERQKKLQVLREAMNVEEPVRRYKTYHGDVFSTSSESPS 420

Query: 421  IISSESDFRQVRRSEASKRFESSSGLPGVDETLSQGQSQRPSRQYETPFEGNLINQEIML 480
            IISSESDFRQVRRSEASKRFESSSGLPGVDETLSQGQSQRPSRQYETPFEGNLINQEIML
Sbjct: 421  IISSESDFRQVRRSEASKRFESSSGLPGVDETLSQGQSQRPSRQYETPFEGNLINQEIML 480

Query: 481  KRQEEELMQLQAKMALRQSRLSLYPGDTIKASMLDITRDPLREIALETAMTQRKLRNFFG 540
            KRQEEELMQLQAKMALRQSRLSLYPGDTIKASMLDITRDPLREIALETAMTQRKLRNFFG
Sbjct: 481  KRQEEELMQLQAKMALRQSRLSLYPGDTIKASMLDITRDPLREIALETAMTQRKLRNFFG 540

Query: 541  PEFVKMTIEPFISLDLPRSILTKKGKNEDNRRKVNIMLLNGQRLELTCDTKTICKDVFDM 600
            PEFVKMTIEPFISLDLPRSILTKKGKNEDNRRKVNIMLLNGQRLELTCDTKTICKDVFDM
Sbjct: 541  PEFVKMTIEPFISLDLPRSILTKKGKNEDNRRKVNIMLLNGQRLELTCDTKTICKDVFDM 600

Query: 601  VVAHIGLVEHHLFALATLKDNEYFFVDPDLKLTKVAPEGWKEEPKKKTKATVNFTLFFRI 660
            VVAHIGLVEHHLFALATLKDNEYFFVDPDLKLTKVAPEGWKEEPKKKTKATVNFTLFFRI
Sbjct: 601  VVAHIGLVEHHLFALATLKDNEYFFVDPDLKLTKVAPEGWKEEPKKKTKATVNFTLFFRI 660

Query: 661  KFFMDDVSLIQHTLTCHQYYLQLRKDILEERMHCDDETSLLLASLALQAEYGDYQPEVHG 720
            KFFMDDVSLIQHTLTCHQYYLQLRKDILEERMHCDDETSLLLASLALQAEYGDYQPEVHG
Sbjct: 661  KFFMDDVSLIQHTLTCHQYYLQLRKDILEERMHCDDETSLLLASLALQAEYGDYQPEVHG 720

Query: 721  VSYFRMEHYLPARVMEKLDLSYIKEELPKLHNTYVGASEKETELEFLKVCQRLTEYGVHF 780
            VSYFRMEHYLPARVMEKLDLSYIKEELPKLHNTYVGASEKETELEFLKVCQRLTEYGVHF
Sbjct: 721  VSYFRMEHYLPARVMEKLDLSYIKEELPKLHNTYVGASEKETELEFLKVCQRLTEYGVHF 780

Query: 781  HRVHPEKKSQTGILLGVCSKGVLVFEVHNGVRTLVLRFPWRETKKISFSKKKITLQNTSD 840
            HRVHPEKKSQTGILLGVCSKGVLVFEVHNGVRTLVLRFPWRETKKISFSKKKITLQNTSD
Sbjct: 781  HRVHPEKKSQTGILLGVCSKGVLVFEVHNGVRTLVLRFPWRETKKISFSKKKITLQNTSD 840

Query: 841  GIKHGFQTDNSKICQYLLHLCSYQHKFQLQMRARQSNQDAQDIE------------RASF 888
            GIKHGFQTDNSKICQYLLHLCSYQHKFQLQMRARQSNQDAQDI+                
Sbjct: 841  GIKHGFQTDNSKICQYLLHLCSYQHKFQLQMRARQSNQDAQDIDVLHKRWSIVSSPEREI 900

Query: 889  RSLNLQAES--------VRGFNMGRAISTGSLASS--------------------TLNKL 920
              +NL+ ++        + G  MGR +  G   SS                    ++N +
Sbjct: 901  TLVNLKKDAKYGLGFQIIGGEKMGR-LDLGIFISSVAPGGPADLDGCLKPGDRLISVNSV 959

Query: 921  AVRPLSVQAEILKRLSCSE---LSLYQPLQNSSKE-------KNDKASWEEKPREMSKSY 970
            ++  +S  A I    +  E   L + QP +  SK         N+  ++ +K   M  S 
Sbjct: 960  SLEGVSHHAAIEILQNAPEDVTLVISQPKEKISKVPSTPVHLTNEMKNYMKKSSYMQDSA 1019

Query: 971  HDLSQASLYPHR---KNVIVNMEPPPQTVAELVGKPSHQMSRSDAESLAG---------- 1017
             D S    +  R   +++  N   P   + E  G  S Q SR+++ SL+           
Sbjct: 1020 IDSSSKDHHWSRGTLRHISENSFGPSGGLRE--GSLSSQDSRTESASLSQSQVNGFFASH 1077

Query: 1018 ------------------VTKLNNSKSVASLNRSPERRKHESDSSSIEDPGQAYVLGMTM 1059
                              ++K    ++    N+S  ++   SD +   D G + +   T 
Sbjct: 1078 LGDQTWQESQHGSPSPSVISKATEKETFTDSNQSKTKKPGISDVTDYSDRGDSDMDEATY 1137

Query: 1060 HSSGNSSSQVPLKE--------NDVLHKRWSIVSSPEREITLVNLKKDAKYGLGFQIIGG 1111
             SS     Q P +E        N +  K +S       +I  V L K+    LG  + GG
Sbjct: 1138 SSS--QDHQTPKQESSSSVNTSNKMNFKTFSSSPPKPGDIFEVELAKNDN-SLGISVTGG 1194

Query: 1112 EKMGRLDLGIFISSVAPGGPADLDGCLKPGDRLISVNSVSLEGVSHHAAIEILQNAPEDV 1171
                    GI++ +V P G A+ DG +  GDR+++VN VSLEG +H  A+E L+N  + V
Sbjct: 1195 VNTSVRHGGIYVKAVIPQGAAESDGRIHKGDRVLAVNGVSLEGATHKQAVETLRNTGQVV 1254

Query: 1172 TLVISQPKEKISK--VPSTP 1189
             L++ + +   SK  VP TP
Sbjct: 1255 HLLLEKGQSPTSKEHVPVTP 1274


>gi|110346438 FERM and PDZ domain containing 2 isoform 1 [Homo
           sapiens]
          Length = 1287

 Score =  297 bits (761), Expect = 8e-80
 Identities = 157/340 (46%), Positives = 225/340 (66%), Gaps = 4/340 (1%)

Query: 538 FFGPEFVKMTIEPFISLDLPRSILTKKGKNEDNRRKVNIMLLNGQRLELTCDTKTICKDV 597
           F  PEF+ +  E  ++L LP S++TKKGK+    R + ++LLNGQ LE+ CD ++    V
Sbjct: 286 FSRPEFILLAGEAPMTLHLPGSVVTKKGKSYLALRDLCVVLLNGQHLEVKCDVESTVGAV 345

Query: 598 FDMVVAHIGLVEHHLFALATLKDNEYFFVDPDLKLTKVAPEGWKEEPKKKTKATVNFTLF 657
           F+ V +   L E   F LA +K  E+FF+D + +L K+APEGW+E+P+K +  T  FTLF
Sbjct: 346 FNAVTSFANLEELTYFGLAYMKSKEFFFLDSETRLCKIAPEGWREQPQKTSMNT--FTLF 403

Query: 658 FRIKFFMDDVSLIQHTLTCHQYYLQLRKDILEERMHCDDETSLLLASLALQAEYGDYQPE 717
            RIKFF+    L+QH+LT HQ+YLQLRKDILEER++C++E  L L  LALQAE+G+Y  E
Sbjct: 404 LRIKFFVSHYGLLQHSLTRHQFYLQLRKDILEERLYCNEEILLQLGVLALQAEFGNYPKE 463

Query: 718 -VHGVSYFRMEHYLPARVMEKLDLSYIKEELPKLHNTYVGASEKETELEFLKVCQRLTEY 776
            V    YF +E Y+PA ++E++    ++ E+ ++H        ++ EL+FL+V Q+L EY
Sbjct: 464 QVESKPYFHVEDYIPASLIERMTALRVQVEVSEMHRLSSALWGEDAELKFLRVTQQLPEY 523

Query: 777 GVHFHRVHPEK-KSQTGILLGVCSKGVLVFEVHNGVRTLVLRFPWRETKKISFSKKKITL 835
           GV  H+V  EK + +  + LG+C+KGV+V+EV N  R  +LRF WRET KIS  +KK T+
Sbjct: 524 GVLVHQVFSEKRRPEEEMALGICAKGVIVYEVKNNSRIAMLRFQWRETGKISTYQKKFTI 583

Query: 836 QNTSDGIKHGFQTDNSKICQYLLHLCSYQHKFQLQMRARQ 875
            ++  G KH F TD++K  +YLL LCS QH F  QM + Q
Sbjct: 584 TSSVTGKKHTFVTDSAKTSKYLLDLCSAQHGFNAQMGSGQ 623



 Score =  220 bits (561), Expect = 1e-56
 Identities = 144/381 (37%), Positives = 205/381 (53%), Gaps = 48/381 (12%)

Query: 1298 DSNQSKTKKPGIS--DVTDYSDRGDSDMDEATYSSSQDHQTPKQESSSSVNTSNKMNFKT 1355
            D  ++ T   G+S  D+  +  +G       +++  QD  T + + +   +   ++  + 
Sbjct: 847  DEEKNSTANSGVSSTDILSFGYQGSL----LSHTQDQDRNTEELDMAGVQSLVPRLRHQL 902

Query: 1356 F--------SSSPPKP-----GDIFEVELAKNDNSLGISVTGGVNTSVRHGGIYVKAVIP 1402
                     SS PP P     G+I+ VEL K D +LG SVTGG+NTSV +GGIYVK+++P
Sbjct: 903  SFLPLKGAGSSCPPSPPEISAGEIYFVELVKEDGTLGFSVTGGINTSVPYGGIYVKSIVP 962

Query: 1403 QGAAESDGRIHKGDRVLAVNGVSLEGATHKQAVETLRNTGQVVHLLLEKGQSPTSKEHVP 1462
             G A  +G+I +GDR+L V+GV L G THKQAV+ L   GQV  L+LE+         VP
Sbjct: 963  GGPAAKEGQILQGDRLLQVDGVILCGLTHKQAVQCLTGPGQVARLVLER--------RVP 1014

Query: 1463 VTPQCTLSDQNAQGQGPEKVKKTTQV----KDYSFVTEENTFEVKLFKNSSGLGFSFSRE 1518
             + Q   S  ++ G     V   T +         VT+   FEVKL KN++GLGFSF + 
Sbjct: 1015 RSTQQCPSANDSMGDERTAVSLVTALPGRPSSCVSVTDGPKFEVKLKKNANGLGFSFVQM 1074

Query: 1519 DNLIPEQINASIVRVKKLFPGQPAAESGKIDVGDVILKVNGASLKGLSQQEVISALRGTA 1578
            +      + + +VR+K+LFPGQPA E+G I  GD+IL VNG S +GL  QEV+  LRG  
Sbjct: 1075 EKESCSHLKSDLVRIKRLFPGQPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAP 1134

Query: 1579 PEVFLLLCRPPPGVLPEIDTALLTPLQSPAQVLPNSSKDSSQPSCVEQSTSSDENEMSDK 1638
             EV LLLCRPPPG LPE++    TP  S       + K+ ++ +C +  TS   ++    
Sbjct: 1135 QEVTLLLCRPPPGALPELEQEWQTPELS-------ADKEFTRATCTDSCTSPILDQ---- 1183

Query: 1639 SKKQCKSPSRRDSYSDSSGSG 1659
                    S RDS S  +G G
Sbjct: 1184 ------EDSWRDSASPDAGEG 1198



 Score =  108 bits (271), Expect = 5e-23
 Identities = 76/208 (36%), Positives = 115/208 (55%), Gaps = 33/208 (15%)

Query: 3   VSLAEALEVRGGPLQEEEIWAVLNQSAESLQELFRKVSLADPAALGFIISPWSLLLLPSG 62
           V+LA AL+VRG  L EEEIW++L  +AE L E  R  S        +++ PWS LL  +G
Sbjct: 15  VTLASALQVRGEALSEEEIWSLLFLAAEQLLEDLRNDSS------DYVVCPWSALLSAAG 68

Query: 63  SVSFTDENISNQDLRAFTAPEVLQNQSLTSLSDVEKIHIYSLGMTLYWGADYEVPQSQPI 122
           S+SF    +S+ +   F APE+LQ QS                       D +   SQP+
Sbjct: 69  SLSFQGR-VSHIEAAPFKAPELLQGQS----------------------EDEQPDASQPL 105

Query: 123 KLGDHLNSILLGMCEDVIYARVSVRTVLDACSAHIRNSNC--APSFSYVKHLVKLVLGNL 180
           +L + L+SILL MCED  + R ++++VL+AC  H +  +   AP+  +++ LV LVLG +
Sbjct: 106 QLCEPLHSILLTMCEDQPHRRCTLQSVLEACRVHEKEVSVYPAPAGLHIRRLVGLVLGTI 165

Query: 181 SGTDQ--LSCNSEQKPDRSQAIRDRLRG 206
           S  ++  +  +S  + +RS  +R RLRG
Sbjct: 166 SEVEKRVVEESSSVQQNRSYLLRKRLRG 193



 Score = 98.6 bits (244), Expect = 7e-20
 Identities = 46/102 (45%), Positives = 71/102 (69%)

Query: 1078 HKRWSIVSSPEREITLVNLKKDAKYGLGFQIIGGEKMGRLDLGIFISSVAPGGPADLDGC 1137
            ++R S ++ P REI  V LK+D   G GF I  GE  G+ D GIFISS+ PGGPA+    
Sbjct: 738  NRRKSFIAEPGREIVRVTLKRDPHRGFGFVINEGEYSGQADPGIFISSIIPGGPAEKAKT 797

Query: 1138 LKPGDRLISVNSVSLEGVSHHAAIEILQNAPEDVTLVISQPK 1179
            +KPG +++++N +SLEG + + A+ ++QN+P+++ L+ISQ K
Sbjct: 798  IKPGGQILALNHISLEGFTFNMAVRMIQNSPDNIELIISQSK 839



 Score = 74.3 bits (181), Expect = 1e-12
 Identities = 75/294 (25%), Positives = 127/294 (43%), Gaps = 56/294 (19%)

Query: 1344 SVNTSNKMNF-KTFSSSPPKPGDIFEVELAKNDN-SLGISVTGGVNTSVRHGGIYVKAVI 1401
            S++  +K N  K+F + P +  +I  V L ++ +   G  +  G  +     GI++ ++I
Sbjct: 730  SMHAGSKNNRRKSFIAEPGR--EIVRVTLKRDPHRGFGFVINEGEYSGQADPGIFISSII 787

Query: 1402 PQGAAESDGRIHKGDRVLAVNGVSLEGATHKQAVETLRNTGQVVHLLLEK-----GQSP- 1455
            P G AE    I  G ++LA+N +SLEG T   AV  ++N+   + L++ +     G +P 
Sbjct: 788  PGGPAEKAKTIKPGGQILALNHISLEGFTFNMAVRMIQNSPDNIELIISQSKGVGGNNPD 847

Query: 1456 -----TSKEHVPVTPQCTLSDQNAQGQGPEKVKKTTQVKD--------------YSF--- 1493
                 T+   V  T   +   Q +     +   + T+  D               SF   
Sbjct: 848  EEKNSTANSGVSSTDILSFGYQGSLLSHTQDQDRNTEELDMAGVQSLVPRLRHQLSFLPL 907

Query: 1494 -------------VTEENTFEVKLFKNSSGLGFSFSREDNLIPEQINASI----VRVKKL 1536
                         ++    + V+L K    LGFS       +   IN S+    + VK +
Sbjct: 908  KGAGSSCPPSPPEISAGEIYFVELVKEDGTLGFS-------VTGGINTSVPYGGIYVKSI 960

Query: 1537 FPGQPAAESGKIDVGDVILKVNGASLKGLSQQEVISALRGTAPEVFLLLCRPPP 1590
             PG PAA+ G+I  GD +L+V+G  L GL+ ++ +  L G      L+L R  P
Sbjct: 961  VPGGPAAKEGQILQGDRLLQVDGVILCGLTHKQAVQCLTGPGQVARLVLERRVP 1014



 Score = 60.8 bits (146), Expect = 2e-08
 Identities = 73/277 (26%), Positives = 110/277 (39%), Gaps = 50/277 (18%)

Query: 1786 ELLITLIKSEKGSLGFTVTKG-NQRI---GCYVHDVIQD-PAKSDGRLKPGDRLIKVNDT 1840
            E+    +  E G+LGF+VT G N  +   G YV  ++   PA  +G++  GDRL++V+  
Sbjct: 925  EIYFVELVKEDGTLGFSVTGGINTSVPYGGIYVKSIVPGGPAAKEGQILQGDRLLQVDGV 984

Query: 1841 DVTNMTHTDAVNLLRAASKTVRLVIGR-------------------------VLELPRIP 1875
             +  +TH  AV  L    +  RLV+ R                         V  LP  P
Sbjct: 985  ILCGLTHKQAVQCLTGPGQVARLVLERRVPRSTQQCPSANDSMGDERTAVSLVTALPGRP 1044

Query: 1876 MLPHLLPD-----ITLTCNKEELGFSL-------CGGHDSLYQVVYISDINPRSVAAIEG 1923
                 + D     + L  N   LGFS        C    S   +V I  + P   A   G
Sbjct: 1045 SSCVSVTDGPKFEVKLKKNANGLGFSFVQMEKESCSHLKS--DLVRIKRLFPGQPAEENG 1102

Query: 1924 NLQLLDVIHYVNGVSTQGMTLEEVNRALDMSLPSLVLKATRNDLPVVPSSKRS----AVS 1979
             +   D+I  VNG ST+G+  +EV   L  +   + L   R     +P  ++      +S
Sbjct: 1103 AIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCRPPPGALPELEQEWQTPELS 1162

Query: 1980 APKSTKGNGSYSVGSCSQPALTPNDSFSTVAGEEINE 2016
            A K  +   +    SC+ P L   DS+   A  +  E
Sbjct: 1163 ADK--EFTRATCTDSCTSPILDQEDSWRDSASPDAGE 1197



 Score = 56.2 bits (134), Expect = 4e-07
 Identities = 36/101 (35%), Positives = 58/101 (57%), Gaps = 9/101 (8%)

Query: 1082 SIVSSPEREITLVNLKKDAKYGLGFQIIGGEKMG----RLDLGIFISSVAPGGPADLDGC 1137
            S+   P+ E   V LKK+A  GLGF  +  EK      + DL + I  + PG PA+ +G 
Sbjct: 1049 SVTDGPKFE---VKLKKNAN-GLGFSFVQMEKESCSHLKSDL-VRIKRLFPGQPAEENGA 1103

Query: 1138 LKPGDRLISVNSVSLEGVSHHAAIEILQNAPEDVTLVISQP 1178
            +  GD +++VN  S EG+     + +L+ AP++VTL++ +P
Sbjct: 1104 IAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCRP 1144



 Score = 54.3 bits (129), Expect = 1e-06
 Identities = 32/88 (36%), Positives = 48/88 (54%), Gaps = 1/88 (1%)

Query: 1090 EITLVNLKKDAKYGLGFQIIGGEKMGRLDLGIFISSVAPGGPADLDGCLKPGDRLISVNS 1149
            EI  V L K+    LGF + GG        GI++ S+ PGGPA  +G +  GDRL+ V+ 
Sbjct: 925  EIYFVELVKEDGT-LGFSVTGGINTSVPYGGIYVKSIVPGGPAAKEGQILQGDRLLQVDG 983

Query: 1150 VSLEGVSHHAAIEILQNAPEDVTLVISQ 1177
            V L G++H  A++ L    +   LV+ +
Sbjct: 984  VILCGLTHKQAVQCLTGPGQVARLVLER 1011



 Score = 32.7 bits (73), Expect = 4.6
 Identities = 18/84 (21%), Positives = 39/84 (46%), Gaps = 5/84 (5%)

Query: 1789 ITLIKSEKGSLGFTVTKGNQR----IGCYVHDVIQD-PAKSDGRLKPGDRLIKVNDTDVT 1843
            +TL +      GF + +G        G ++  +I   PA+    +KPG +++ +N   + 
Sbjct: 754  VTLKRDPHRGFGFVINEGEYSGQADPGIFISSIIPGGPAEKAKTIKPGGQILALNHISLE 813

Query: 1844 NMTHTDAVNLLRAASKTVRLVIGR 1867
              T   AV +++ +   + L+I +
Sbjct: 814  GFTFNMAVRMIQNSPDNIELIISQ 837


>gi|110346436 FERM and PDZ domain containing 2 isoform 3 [Homo
           sapiens]
          Length = 1309

 Score =  297 bits (761), Expect = 8e-80
 Identities = 157/340 (46%), Positives = 225/340 (66%), Gaps = 4/340 (1%)

Query: 538 FFGPEFVKMTIEPFISLDLPRSILTKKGKNEDNRRKVNIMLLNGQRLELTCDTKTICKDV 597
           F  PEF+ +  E  ++L LP S++TKKGK+    R + ++LLNGQ LE+ CD ++    V
Sbjct: 308 FSRPEFILLAGEAPMTLHLPGSVVTKKGKSYLALRDLCVVLLNGQHLEVKCDVESTVGAV 367

Query: 598 FDMVVAHIGLVEHHLFALATLKDNEYFFVDPDLKLTKVAPEGWKEEPKKKTKATVNFTLF 657
           F+ V +   L E   F LA +K  E+FF+D + +L K+APEGW+E+P+K +  T  FTLF
Sbjct: 368 FNAVTSFANLEELTYFGLAYMKSKEFFFLDSETRLCKIAPEGWREQPQKTSMNT--FTLF 425

Query: 658 FRIKFFMDDVSLIQHTLTCHQYYLQLRKDILEERMHCDDETSLLLASLALQAEYGDYQPE 717
            RIKFF+    L+QH+LT HQ+YLQLRKDILEER++C++E  L L  LALQAE+G+Y  E
Sbjct: 426 LRIKFFVSHYGLLQHSLTRHQFYLQLRKDILEERLYCNEEILLQLGVLALQAEFGNYPKE 485

Query: 718 -VHGVSYFRMEHYLPARVMEKLDLSYIKEELPKLHNTYVGASEKETELEFLKVCQRLTEY 776
            V    YF +E Y+PA ++E++    ++ E+ ++H        ++ EL+FL+V Q+L EY
Sbjct: 486 QVESKPYFHVEDYIPASLIERMTALRVQVEVSEMHRLSSALWGEDAELKFLRVTQQLPEY 545

Query: 777 GVHFHRVHPEK-KSQTGILLGVCSKGVLVFEVHNGVRTLVLRFPWRETKKISFSKKKITL 835
           GV  H+V  EK + +  + LG+C+KGV+V+EV N  R  +LRF WRET KIS  +KK T+
Sbjct: 546 GVLVHQVFSEKRRPEEEMALGICAKGVIVYEVKNNSRIAMLRFQWRETGKISTYQKKFTI 605

Query: 836 QNTSDGIKHGFQTDNSKICQYLLHLCSYQHKFQLQMRARQ 875
            ++  G KH F TD++K  +YLL LCS QH F  QM + Q
Sbjct: 606 TSSVTGKKHTFVTDSAKTSKYLLDLCSAQHGFNAQMGSGQ 645



 Score =  220 bits (561), Expect = 1e-56
 Identities = 144/381 (37%), Positives = 205/381 (53%), Gaps = 48/381 (12%)

Query: 1298 DSNQSKTKKPGIS--DVTDYSDRGDSDMDEATYSSSQDHQTPKQESSSSVNTSNKMNFKT 1355
            D  ++ T   G+S  D+  +  +G       +++  QD  T + + +   +   ++  + 
Sbjct: 869  DEEKNSTANSGVSSTDILSFGYQGSL----LSHTQDQDRNTEELDMAGVQSLVPRLRHQL 924

Query: 1356 F--------SSSPPKP-----GDIFEVELAKNDNSLGISVTGGVNTSVRHGGIYVKAVIP 1402
                     SS PP P     G+I+ VEL K D +LG SVTGG+NTSV +GGIYVK+++P
Sbjct: 925  SFLPLKGAGSSCPPSPPEISAGEIYFVELVKEDGTLGFSVTGGINTSVPYGGIYVKSIVP 984

Query: 1403 QGAAESDGRIHKGDRVLAVNGVSLEGATHKQAVETLRNTGQVVHLLLEKGQSPTSKEHVP 1462
             G A  +G+I +GDR+L V+GV L G THKQAV+ L   GQV  L+LE+         VP
Sbjct: 985  GGPAAKEGQILQGDRLLQVDGVILCGLTHKQAVQCLTGPGQVARLVLER--------RVP 1036

Query: 1463 VTPQCTLSDQNAQGQGPEKVKKTTQV----KDYSFVTEENTFEVKLFKNSSGLGFSFSRE 1518
             + Q   S  ++ G     V   T +         VT+   FEVKL KN++GLGFSF + 
Sbjct: 1037 RSTQQCPSANDSMGDERTAVSLVTALPGRPSSCVSVTDGPKFEVKLKKNANGLGFSFVQM 1096

Query: 1519 DNLIPEQINASIVRVKKLFPGQPAAESGKIDVGDVILKVNGASLKGLSQQEVISALRGTA 1578
            +      + + +VR+K+LFPGQPA E+G I  GD+IL VNG S +GL  QEV+  LRG  
Sbjct: 1097 EKESCSHLKSDLVRIKRLFPGQPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAP 1156

Query: 1579 PEVFLLLCRPPPGVLPEIDTALLTPLQSPAQVLPNSSKDSSQPSCVEQSTSSDENEMSDK 1638
             EV LLLCRPPPG LPE++    TP  S       + K+ ++ +C +  TS   ++    
Sbjct: 1157 QEVTLLLCRPPPGALPELEQEWQTPELS-------ADKEFTRATCTDSCTSPILDQ---- 1205

Query: 1639 SKKQCKSPSRRDSYSDSSGSG 1659
                    S RDS S  +G G
Sbjct: 1206 ------EDSWRDSASPDAGEG 1220



 Score =  150 bits (379), Expect = 2e-35
 Identities = 88/208 (42%), Positives = 130/208 (62%), Gaps = 11/208 (5%)

Query: 3   VSLAEALEVRGGPLQEEEIWAVLNQSAESLQELFRKVSLADPAALGFIISPWSLLLLPSG 62
           V+LA AL+VRG  L EEEIW++L  +AE L E  R  S        +++ PWS LL  +G
Sbjct: 15  VTLASALQVRGEALSEEEIWSLLFLAAEQLLEDLRNDSS------DYVVCPWSALLSAAG 68

Query: 63  SVSFTDENISNQDLRAFTAPEVLQNQSLTSLSDVEKIHIYSLGMTLYWGADYEVPQSQPI 122
           S+SF    +S+ +   F APE+LQ QS     D  ++H+YSLGMTLYW A + VP  QP+
Sbjct: 69  SLSFQGR-VSHIEAAPFKAPELLQGQSEDEQPDASQMHVYSLGMTLYWSAGFHVPPHQPL 127

Query: 123 KLGDHLNSILLGMCEDVIYARVSVRTVLDACSAHIRNSNC--APSFSYVKHLVKLVLGNL 180
           +L + L+SILL MCED  + R ++++VL+AC  H +  +   AP+  +++ LV LVLG +
Sbjct: 128 QLCEPLHSILLTMCEDQPHRRCTLQSVLEACRVHEKEVSVYPAPAGLHIRRLVGLVLGTI 187

Query: 181 SGTDQ--LSCNSEQKPDRSQAIRDRLRG 206
           S  ++  +  +S  + +RS  +R RLRG
Sbjct: 188 SEVEKRVVEESSSVQQNRSYLLRKRLRG 215



 Score = 98.6 bits (244), Expect = 7e-20
 Identities = 46/102 (45%), Positives = 71/102 (69%)

Query: 1078 HKRWSIVSSPEREITLVNLKKDAKYGLGFQIIGGEKMGRLDLGIFISSVAPGGPADLDGC 1137
            ++R S ++ P REI  V LK+D   G GF I  GE  G+ D GIFISS+ PGGPA+    
Sbjct: 760  NRRKSFIAEPGREIVRVTLKRDPHRGFGFVINEGEYSGQADPGIFISSIIPGGPAEKAKT 819

Query: 1138 LKPGDRLISVNSVSLEGVSHHAAIEILQNAPEDVTLVISQPK 1179
            +KPG +++++N +SLEG + + A+ ++QN+P+++ L+ISQ K
Sbjct: 820  IKPGGQILALNHISLEGFTFNMAVRMIQNSPDNIELIISQSK 861



 Score = 74.3 bits (181), Expect = 1e-12
 Identities = 75/294 (25%), Positives = 127/294 (43%), Gaps = 56/294 (19%)

Query: 1344 SVNTSNKMNF-KTFSSSPPKPGDIFEVELAKNDN-SLGISVTGGVNTSVRHGGIYVKAVI 1401
            S++  +K N  K+F + P +  +I  V L ++ +   G  +  G  +     GI++ ++I
Sbjct: 752  SMHAGSKNNRRKSFIAEPGR--EIVRVTLKRDPHRGFGFVINEGEYSGQADPGIFISSII 809

Query: 1402 PQGAAESDGRIHKGDRVLAVNGVSLEGATHKQAVETLRNTGQVVHLLLEK-----GQSP- 1455
            P G AE    I  G ++LA+N +SLEG T   AV  ++N+   + L++ +     G +P 
Sbjct: 810  PGGPAEKAKTIKPGGQILALNHISLEGFTFNMAVRMIQNSPDNIELIISQSKGVGGNNPD 869

Query: 1456 -----TSKEHVPVTPQCTLSDQNAQGQGPEKVKKTTQVKD--------------YSF--- 1493
                 T+   V  T   +   Q +     +   + T+  D               SF   
Sbjct: 870  EEKNSTANSGVSSTDILSFGYQGSLLSHTQDQDRNTEELDMAGVQSLVPRLRHQLSFLPL 929

Query: 1494 -------------VTEENTFEVKLFKNSSGLGFSFSREDNLIPEQINASI----VRVKKL 1536
                         ++    + V+L K    LGFS       +   IN S+    + VK +
Sbjct: 930  KGAGSSCPPSPPEISAGEIYFVELVKEDGTLGFS-------VTGGINTSVPYGGIYVKSI 982

Query: 1537 FPGQPAAESGKIDVGDVILKVNGASLKGLSQQEVISALRGTAPEVFLLLCRPPP 1590
             PG PAA+ G+I  GD +L+V+G  L GL+ ++ +  L G      L+L R  P
Sbjct: 983  VPGGPAAKEGQILQGDRLLQVDGVILCGLTHKQAVQCLTGPGQVARLVLERRVP 1036



 Score = 60.8 bits (146), Expect = 2e-08
 Identities = 73/277 (26%), Positives = 110/277 (39%), Gaps = 50/277 (18%)

Query: 1786 ELLITLIKSEKGSLGFTVTKG-NQRI---GCYVHDVIQD-PAKSDGRLKPGDRLIKVNDT 1840
            E+    +  E G+LGF+VT G N  +   G YV  ++   PA  +G++  GDRL++V+  
Sbjct: 947  EIYFVELVKEDGTLGFSVTGGINTSVPYGGIYVKSIVPGGPAAKEGQILQGDRLLQVDGV 1006

Query: 1841 DVTNMTHTDAVNLLRAASKTVRLVIGR-------------------------VLELPRIP 1875
             +  +TH  AV  L    +  RLV+ R                         V  LP  P
Sbjct: 1007 ILCGLTHKQAVQCLTGPGQVARLVLERRVPRSTQQCPSANDSMGDERTAVSLVTALPGRP 1066

Query: 1876 MLPHLLPD-----ITLTCNKEELGFSL-------CGGHDSLYQVVYISDINPRSVAAIEG 1923
                 + D     + L  N   LGFS        C    S   +V I  + P   A   G
Sbjct: 1067 SSCVSVTDGPKFEVKLKKNANGLGFSFVQMEKESCSHLKS--DLVRIKRLFPGQPAEENG 1124

Query: 1924 NLQLLDVIHYVNGVSTQGMTLEEVNRALDMSLPSLVLKATRNDLPVVPSSKRS----AVS 1979
             +   D+I  VNG ST+G+  +EV   L  +   + L   R     +P  ++      +S
Sbjct: 1125 AIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCRPPPGALPELEQEWQTPELS 1184

Query: 1980 APKSTKGNGSYSVGSCSQPALTPNDSFSTVAGEEINE 2016
            A K  +   +    SC+ P L   DS+   A  +  E
Sbjct: 1185 ADK--EFTRATCTDSCTSPILDQEDSWRDSASPDAGE 1219



 Score = 56.2 bits (134), Expect = 4e-07
 Identities = 36/101 (35%), Positives = 58/101 (57%), Gaps = 9/101 (8%)

Query: 1082 SIVSSPEREITLVNLKKDAKYGLGFQIIGGEKMG----RLDLGIFISSVAPGGPADLDGC 1137
            S+   P+ E   V LKK+A  GLGF  +  EK      + DL + I  + PG PA+ +G 
Sbjct: 1071 SVTDGPKFE---VKLKKNAN-GLGFSFVQMEKESCSHLKSDL-VRIKRLFPGQPAEENGA 1125

Query: 1138 LKPGDRLISVNSVSLEGVSHHAAIEILQNAPEDVTLVISQP 1178
            +  GD +++VN  S EG+     + +L+ AP++VTL++ +P
Sbjct: 1126 IAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCRP 1166



 Score = 54.3 bits (129), Expect = 1e-06
 Identities = 32/88 (36%), Positives = 48/88 (54%), Gaps = 1/88 (1%)

Query: 1090 EITLVNLKKDAKYGLGFQIIGGEKMGRLDLGIFISSVAPGGPADLDGCLKPGDRLISVNS 1149
            EI  V L K+    LGF + GG        GI++ S+ PGGPA  +G +  GDRL+ V+ 
Sbjct: 947  EIYFVELVKEDGT-LGFSVTGGINTSVPYGGIYVKSIVPGGPAAKEGQILQGDRLLQVDG 1005

Query: 1150 VSLEGVSHHAAIEILQNAPEDVTLVISQ 1177
            V L G++H  A++ L    +   LV+ +
Sbjct: 1006 VILCGLTHKQAVQCLTGPGQVARLVLER 1033



 Score = 32.7 bits (73), Expect = 4.6
 Identities = 18/84 (21%), Positives = 39/84 (46%), Gaps = 5/84 (5%)

Query: 1789 ITLIKSEKGSLGFTVTKGNQR----IGCYVHDVIQD-PAKSDGRLKPGDRLIKVNDTDVT 1843
            +TL +      GF + +G        G ++  +I   PA+    +KPG +++ +N   + 
Sbjct: 776  VTLKRDPHRGFGFVINEGEYSGQADPGIFISSIIPGGPAEKAKTIKPGGQILALNHISLE 835

Query: 1844 NMTHTDAVNLLRAASKTVRLVIGR 1867
              T   AV +++ +   + L+I +
Sbjct: 836  GFTFNMAVRMIQNSPDNIELIISQ 859


>gi|109138573 protein tyrosine phosphatase, non-receptor type 20A
            isoform 8 [Homo sapiens]
          Length = 339

 Score =  239 bits (609), Expect = 3e-62
 Identities = 117/240 (48%), Positives = 156/240 (65%), Gaps = 1/240 (0%)

Query: 2232 GQTKENRRKNRYKNILPYDATRVPLGDEGGYINASFIKIPVGKEEFVYIACQGPLPTTVG 2291
            G    NR KNRY++ILPYD+TRVPLG    YINAS+I+I    EE+ YIA QGPL +T+ 
Sbjct: 97   GNQPSNREKNRYRDILPYDSTRVPLGKSKDYINASYIRIVNCGEEYFYIATQGPLLSTID 156

Query: 2292 DFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSNRLRLALVRMQQLKGFV 2351
            DFWQM+ E  S VIAM+T+E+EG  IKC  YWP  L K   + +  R+ L   Q L+ F+
Sbjct: 157  DFWQMVLENNSNVIAMITREIEGGIIKCYHYWPISLKKPLELKH-FRVFLENYQILQYFI 215

Query: 2352 VRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYMRHIHRSGPIITHCSAG 2411
            +R   + +  T     +  L FT WPDH TP+  D  + +I Y R  H +GP++ HCSAG
Sbjct: 216  IRMFQVVEKSTGTSHSVKQLQFTKWPDHGTPASADSFIKYIRYARKSHLTGPMVVHCSAG 275

Query: 2412 IGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTEDQYIFCYQVILYVLTRL 2471
            IGR+G  +C+DVV   I ++  F+I D+V  MR QR GMVQT++QY FCY ++L VL +L
Sbjct: 276  IGRTGVFLCVDVVFCAIVKNCSFNIMDIVAQMREQRSGMVQTKEQYHFCYDIVLEVLRKL 335


>gi|109138561 protein tyrosine phosphatase, non-receptor type 20A
            isoform 3 [Homo sapiens]
          Length = 411

 Score =  239 bits (609), Expect = 3e-62
 Identities = 117/240 (48%), Positives = 156/240 (65%), Gaps = 1/240 (0%)

Query: 2232 GQTKENRRKNRYKNILPYDATRVPLGDEGGYINASFIKIPVGKEEFVYIACQGPLPTTVG 2291
            G    NR KNRY++ILPYD+TRVPLG    YINAS+I+I    EE+ YIA QGPL +T+ 
Sbjct: 169  GNQPSNREKNRYRDILPYDSTRVPLGKSKDYINASYIRIVNCGEEYFYIATQGPLLSTID 228

Query: 2292 DFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSNRLRLALVRMQQLKGFV 2351
            DFWQM+ E  S VIAM+T+E+EG  IKC  YWP  L K   + +  R+ L   Q L+ F+
Sbjct: 229  DFWQMVLENNSNVIAMITREIEGGIIKCYHYWPISLKKPLELKH-FRVFLENYQILQYFI 287

Query: 2352 VRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYMRHIHRSGPIITHCSAG 2411
            +R   + +  T     +  L FT WPDH TP+  D  + +I Y R  H +GP++ HCSAG
Sbjct: 288  IRMFQVVEKSTGTSHSVKQLQFTKWPDHGTPASADSFIKYIRYARKSHLTGPMVVHCSAG 347

Query: 2412 IGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTEDQYIFCYQVILYVLTRL 2471
            IGR+G  +C+DVV   I ++  F+I D+V  MR QR GMVQT++QY FCY ++L VL +L
Sbjct: 348  IGRTGVFLCVDVVFCAIVKNCSFNIMDIVAQMREQRSGMVQTKEQYHFCYDIVLEVLRKL 407


>gi|109138557 protein tyrosine phosphatase, non-receptor type 20A
            isoform 1 [Homo sapiens]
          Length = 420

 Score =  239 bits (609), Expect = 3e-62
 Identities = 117/240 (48%), Positives = 156/240 (65%), Gaps = 1/240 (0%)

Query: 2232 GQTKENRRKNRYKNILPYDATRVPLGDEGGYINASFIKIPVGKEEFVYIACQGPLPTTVG 2291
            G    NR KNRY++ILPYD+TRVPLG    YINAS+I+I    EE+ YIA QGPL +T+ 
Sbjct: 178  GNQPSNREKNRYRDILPYDSTRVPLGKSKDYINASYIRIVNCGEEYFYIATQGPLLSTID 237

Query: 2292 DFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSNRLRLALVRMQQLKGFV 2351
            DFWQM+ E  S VIAM+T+E+EG  IKC  YWP  L K   + +  R+ L   Q L+ F+
Sbjct: 238  DFWQMVLENNSNVIAMITREIEGGIIKCYHYWPISLKKPLELKH-FRVFLENYQILQYFI 296

Query: 2352 VRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYMRHIHRSGPIITHCSAG 2411
            +R   + +  T     +  L FT WPDH TP+  D  + +I Y R  H +GP++ HCSAG
Sbjct: 297  IRMFQVVEKSTGTSHSVKQLQFTKWPDHGTPASADSFIKYIRYARKSHLTGPMVVHCSAG 356

Query: 2412 IGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTEDQYIFCYQVILYVLTRL 2471
            IGR+G  +C+DVV   I ++  F+I D+V  MR QR GMVQT++QY FCY ++L VL +L
Sbjct: 357  IGRTGVFLCVDVVFCAIVKNCSFNIMDIVAQMREQRSGMVQTKEQYHFCYDIVLEVLRKL 416


>gi|108802617 protein tyrosine phosphatase, non-receptor type 20
            isoform 8 [Homo sapiens]
          Length = 339

 Score =  239 bits (609), Expect = 3e-62
 Identities = 117/240 (48%), Positives = 156/240 (65%), Gaps = 1/240 (0%)

Query: 2232 GQTKENRRKNRYKNILPYDATRVPLGDEGGYINASFIKIPVGKEEFVYIACQGPLPTTVG 2291
            G    NR KNRY++ILPYD+TRVPLG    YINAS+I+I    EE+ YIA QGPL +T+ 
Sbjct: 97   GNQPSNREKNRYRDILPYDSTRVPLGKSKDYINASYIRIVNCGEEYFYIATQGPLLSTID 156

Query: 2292 DFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSNRLRLALVRMQQLKGFV 2351
            DFWQM+ E  S VIAM+T+E+EG  IKC  YWP  L K   + +  R+ L   Q L+ F+
Sbjct: 157  DFWQMVLENNSNVIAMITREIEGGIIKCYHYWPISLKKPLELKH-FRVFLENYQILQYFI 215

Query: 2352 VRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYMRHIHRSGPIITHCSAG 2411
            +R   + +  T     +  L FT WPDH TP+  D  + +I Y R  H +GP++ HCSAG
Sbjct: 216  IRMFQVVEKSTGTSHSVKQLQFTKWPDHGTPASADSFIKYIRYARKSHLTGPMVVHCSAG 275

Query: 2412 IGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTEDQYIFCYQVILYVLTRL 2471
            IGR+G  +C+DVV   I ++  F+I D+V  MR QR GMVQT++QY FCY ++L VL +L
Sbjct: 276  IGRTGVFLCVDVVFCAIVKNCSFNIMDIVAQMREQRSGMVQTKEQYHFCYDIVLEVLRKL 335


>gi|108802607 protein tyrosine phosphatase, non-receptor type 20
            isoform 3 [Homo sapiens]
          Length = 411

 Score =  239 bits (609), Expect = 3e-62
 Identities = 117/240 (48%), Positives = 156/240 (65%), Gaps = 1/240 (0%)

Query: 2232 GQTKENRRKNRYKNILPYDATRVPLGDEGGYINASFIKIPVGKEEFVYIACQGPLPTTVG 2291
            G    NR KNRY++ILPYD+TRVPLG    YINAS+I+I    EE+ YIA QGPL +T+ 
Sbjct: 169  GNQPSNREKNRYRDILPYDSTRVPLGKSKDYINASYIRIVNCGEEYFYIATQGPLLSTID 228

Query: 2292 DFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSNRLRLALVRMQQLKGFV 2351
            DFWQM+ E  S VIAM+T+E+EG  IKC  YWP  L K   + +  R+ L   Q L+ F+
Sbjct: 229  DFWQMVLENNSNVIAMITREIEGGIIKCYHYWPISLKKPLELKH-FRVFLENYQILQYFI 287

Query: 2352 VRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYMRHIHRSGPIITHCSAG 2411
            +R   + +  T     +  L FT WPDH TP+  D  + +I Y R  H +GP++ HCSAG
Sbjct: 288  IRMFQVVEKSTGTSHSVKQLQFTKWPDHGTPASADSFIKYIRYARKSHLTGPMVVHCSAG 347

Query: 2412 IGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTEDQYIFCYQVILYVLTRL 2471
            IGR+G  +C+DVV   I ++  F+I D+V  MR QR GMVQT++QY FCY ++L VL +L
Sbjct: 348  IGRTGVFLCVDVVFCAIVKNCSFNIMDIVAQMREQRSGMVQTKEQYHFCYDIVLEVLRKL 407


>gi|108802604 protein tyrosine phosphatase, non-receptor type 20
            isoform 1 [Homo sapiens]
          Length = 420

 Score =  239 bits (609), Expect = 3e-62
 Identities = 117/240 (48%), Positives = 156/240 (65%), Gaps = 1/240 (0%)

Query: 2232 GQTKENRRKNRYKNILPYDATRVPLGDEGGYINASFIKIPVGKEEFVYIACQGPLPTTVG 2291
            G    NR KNRY++ILPYD+TRVPLG    YINAS+I+I    EE+ YIA QGPL +T+ 
Sbjct: 178  GNQPSNREKNRYRDILPYDSTRVPLGKSKDYINASYIRIVNCGEEYFYIATQGPLLSTID 237

Query: 2292 DFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSNRLRLALVRMQQLKGFV 2351
            DFWQM+ E  S VIAM+T+E+EG  IKC  YWP  L K   + +  R+ L   Q L+ F+
Sbjct: 238  DFWQMVLENNSNVIAMITREIEGGIIKCYHYWPISLKKPLELKH-FRVFLENYQILQYFI 296

Query: 2352 VRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYMRHIHRSGPIITHCSAG 2411
            +R   + +  T     +  L FT WPDH TP+  D  + +I Y R  H +GP++ HCSAG
Sbjct: 297  IRMFQVVEKSTGTSHSVKQLQFTKWPDHGTPASADSFIKYIRYARKSHLTGPMVVHCSAG 356

Query: 2412 IGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTEDQYIFCYQVILYVLTRL 2471
            IGR+G  +C+DVV   I ++  F+I D+V  MR QR GMVQT++QY FCY ++L VL +L
Sbjct: 357  IGRTGVFLCVDVVFCAIVKNCSFNIMDIVAQMREQRSGMVQTKEQYHFCYDIVLEVLRKL 416


>gi|108802611 protein tyrosine phosphatase, non-receptor type 20
            isoform 5 [Homo sapiens]
          Length = 228

 Score =  214 bits (546), Expect = 6e-55
 Identities = 106/222 (47%), Positives = 143/222 (64%), Gaps = 1/222 (0%)

Query: 2250 DATRVPLGDEGGYINASFIKIPVGKEEFVYIACQGPLPTTVGDFWQMIWEQKSTVIAMMT 2309
            D+TRVPLG    YINAS+I+I    EE+ YIA QGPL +T+ DFWQM+ E  S VIAM+T
Sbjct: 4    DSTRVPLGKSKDYINASYIRIVNCGEEYFYIATQGPLLSTIDDFWQMVLENNSNVIAMIT 63

Query: 2310 QEVEGEKIKCQRYWPNILGKTTMVSNRLRLALVRMQQLKGFVVRAMTLEDIQTREVRHIS 2369
            +E+EG  IKC  YWP  L K   + +  R+ L   Q L+ F++R   + +  T     + 
Sbjct: 64   REIEGGIIKCYHYWPISLKKPLELKH-FRVFLENYQILQYFIIRMFQVVEKSTGTSHSVK 122

Query: 2370 HLNFTAWPDHDTPSQPDDLLTFISYMRHIHRSGPIITHCSAGIGRSGTLICIDVVLGLIS 2429
             L FT WPDH TP+  D  + +I Y R  H +GP++ HCSAGIGR+G  +C+DVV   I 
Sbjct: 123  QLQFTKWPDHGTPASADSFIKYIRYARKSHLTGPMVVHCSAGIGRTGVFLCVDVVFCAIV 182

Query: 2430 QDLDFDISDLVRCMRLQRHGMVQTEDQYIFCYQVILYVLTRL 2471
            ++  F+I D+V  MR QR GMVQT++QY FCY ++L VL +L
Sbjct: 183  KNCSFNIMDIVAQMREQRSGMVQTKEQYHFCYDIVLEVLRKL 224


>gi|109138565 protein tyrosine phosphatase, non-receptor type 20A
            isoform 5 [Homo sapiens]
          Length = 228

 Score =  214 bits (546), Expect = 6e-55
 Identities = 106/222 (47%), Positives = 143/222 (64%), Gaps = 1/222 (0%)

Query: 2250 DATRVPLGDEGGYINASFIKIPVGKEEFVYIACQGPLPTTVGDFWQMIWEQKSTVIAMMT 2309
            D+TRVPLG    YINAS+I+I    EE+ YIA QGPL +T+ DFWQM+ E  S VIAM+T
Sbjct: 4    DSTRVPLGKSKDYINASYIRIVNCGEEYFYIATQGPLLSTIDDFWQMVLENNSNVIAMIT 63

Query: 2310 QEVEGEKIKCQRYWPNILGKTTMVSNRLRLALVRMQQLKGFVVRAMTLEDIQTREVRHIS 2369
            +E+EG  IKC  YWP  L K   + +  R+ L   Q L+ F++R   + +  T     + 
Sbjct: 64   REIEGGIIKCYHYWPISLKKPLELKH-FRVFLENYQILQYFIIRMFQVVEKSTGTSHSVK 122

Query: 2370 HLNFTAWPDHDTPSQPDDLLTFISYMRHIHRSGPIITHCSAGIGRSGTLICIDVVLGLIS 2429
             L FT WPDH TP+  D  + +I Y R  H +GP++ HCSAGIGR+G  +C+DVV   I 
Sbjct: 123  QLQFTKWPDHGTPASADSFIKYIRYARKSHLTGPMVVHCSAGIGRTGVFLCVDVVFCAIV 182

Query: 2430 QDLDFDISDLVRCMRLQRHGMVQTEDQYIFCYQVILYVLTRL 2471
            ++  F+I D+V  MR QR GMVQT++QY FCY ++L VL +L
Sbjct: 183  KNCSFNIMDIVAQMREQRSGMVQTKEQYHFCYDIVLEVLRKL 224


>gi|241896926 protein tyrosine phosphatase, receptor type, H isoform 2
            precursor [Homo sapiens]
          Length = 937

 Score =  194 bits (492), Expect = 1e-48
 Identities = 107/261 (40%), Positives = 150/261 (57%), Gaps = 13/261 (4%)

Query: 2230 LIGQTKENRRKNRYKNILPYDATRVPLG---DEGG--YINASFIKIPVGKEEFVYIACQG 2284
            ++    EN  KNRY+N+LPYD +RVPL    +E G  YINASF+      +EF  IA QG
Sbjct: 659  MVASASENNAKNRYRNVLPYDWSRVPLKPIHEEPGSDYINASFMPGLWSPQEF--IATQG 716

Query: 2285 PLPTTVGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSNRLRLALVRM 2344
            PLP TVGDFW+++WEQ+S  + M+T  +E  ++KC+ YWP  L         LR+ LV  
Sbjct: 717  PLPQTVGDFWRLVWEQQSHTLVMLTNCMEAGRVKCEHYWP--LDSQPCTHGHLRVTLVGE 774

Query: 2345 QQLKGFVVRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYMR----HIHR 2400
            + ++ + VR + L  ++ ++   +   ++ AWPDH  PS PD LL F   +R        
Sbjct: 775  EVMENWTVRELLLLQVEEQKTLSVRQFHYQAWPDHGVPSSPDTLLAFWRMLRQWLDQTME 834

Query: 2401 SGPIITHCSAGIGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTEDQYIFC 2460
             GP I HCSAG+GR+GTLI +DV+L  +  +        VR MR  R  MVQTE QY+F 
Sbjct: 835  GGPPIVHCSAGVGRTGTLIALDVLLRQLQSEGLLGPFSFVRKMRESRPLMVQTEAQYVFL 894

Query: 2461 YQVILYVLTRLQAEEEQKQQP 2481
            +Q IL  L +      +K+ P
Sbjct: 895  HQCILRFLQQSAQAPAEKEVP 915


>gi|241896924 protein tyrosine phosphatase, receptor type, H isoform 1
            precursor [Homo sapiens]
          Length = 1115

 Score =  194 bits (492), Expect = 1e-48
 Identities = 107/261 (40%), Positives = 150/261 (57%), Gaps = 13/261 (4%)

Query: 2230 LIGQTKENRRKNRYKNILPYDATRVPLG---DEGG--YINASFIKIPVGKEEFVYIACQG 2284
            ++    EN  KNRY+N+LPYD +RVPL    +E G  YINASF+      +EF  IA QG
Sbjct: 837  MVASASENNAKNRYRNVLPYDWSRVPLKPIHEEPGSDYINASFMPGLWSPQEF--IATQG 894

Query: 2285 PLPTTVGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSNRLRLALVRM 2344
            PLP TVGDFW+++WEQ+S  + M+T  +E  ++KC+ YWP  L         LR+ LV  
Sbjct: 895  PLPQTVGDFWRLVWEQQSHTLVMLTNCMEAGRVKCEHYWP--LDSQPCTHGHLRVTLVGE 952

Query: 2345 QQLKGFVVRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYMR----HIHR 2400
            + ++ + VR + L  ++ ++   +   ++ AWPDH  PS PD LL F   +R        
Sbjct: 953  EVMENWTVRELLLLQVEEQKTLSVRQFHYQAWPDHGVPSSPDTLLAFWRMLRQWLDQTME 1012

Query: 2401 SGPIITHCSAGIGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTEDQYIFC 2460
             GP I HCSAG+GR+GTLI +DV+L  +  +        VR MR  R  MVQTE QY+F 
Sbjct: 1013 GGPPIVHCSAGVGRTGTLIALDVLLRQLQSEGLLGPFSFVRKMRESRPLMVQTEAQYVFL 1072

Query: 2461 YQVILYVLTRLQAEEEQKQQP 2481
            +Q IL  L +      +K+ P
Sbjct: 1073 HQCILRFLQQSAQAPAEKEVP 1093


>gi|223941891 protein tyrosine phosphatase, non-receptor type 3
            isoform 6 [Homo sapiens]
          Length = 581

 Score =  190 bits (482), Expect = 2e-47
 Identities = 110/299 (36%), Positives = 156/299 (52%), Gaps = 5/299 (1%)

Query: 2172 FLTNDELAVLPVVKVLPSGKYTGANLKSVIRVLRGLLDQGIPSKELENLQELKPLDQCLI 2231
            F + DEL  L    + P     G  L+  +  L+  L+ G    + E L   KP      
Sbjct: 273  FKSEDELNQLFPEAIFPMCPEGGDTLEGSMAQLKKGLESGTVLIQFEQLYRKKPGLAITF 332

Query: 2232 GQTKENRRKNRYKNILPYDATRVPLGDEGGYINASFIKIPVGKEEFV--YIACQGPLPTT 2289
             +  +N  KNRYK++LPYD TRV L     YINAS++ + +     V  YIA QGPLP T
Sbjct: 333  AKLPQNLDKNRYKDVLPYDTTRVLLQGNEDYINASYVNMEIPAANLVNKYIATQGPLPHT 392

Query: 2290 VGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSNRLRLALVRMQQLKG 2349
               FWQ++W+QK ++I M+T   E  + KC +YWP+      M      +          
Sbjct: 393  CAQFWQVVWDQKLSLIVMLTTLTERGRTKCHQYWPD--PPDVMNHGGFHIQCQSEDCTIA 450

Query: 2350 FVVRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYMRHIH-RSGPIITHC 2408
            +V R M + + QT E   ++HL + AWPDH  P    D L F++Y+R +   S P++ HC
Sbjct: 451  YVSREMLVTNTQTGEEHTVTHLQYVAWPDHGVPDDSSDFLEFVNYVRSLRVDSEPVLVHC 510

Query: 2409 SAGIGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTEDQYIFCYQVILYV 2467
            SAGIGR+G L+ ++  + L  ++L     D+VR MR QR  MVQT  QY F  + IL V
Sbjct: 511  SAGIGRTGVLVTMETAMCLTERNLPIYPLDIVRKMRDQRAMMVQTSSQYKFVCEAILRV 569



 Score = 39.7 bits (91), Expect = 0.037
 Identities = 56/256 (21%), Positives = 103/256 (40%), Gaps = 34/256 (13%)

Query: 1625 EQSTSSDENEMSDKSKKQCKSPSRRDSYSDSSGSGEDDL------VTAPANISNSTWSSA 1678
            E++  S    M  ++ K+ +SP  R        S  D+L      +T   ++  +   S 
Sbjct: 30   EKNVLSQYWTMGSRNTKK-RSPRLRHEIRKPRHSSADNLANEMTYITETEDVFYTYKGSL 88

Query: 1679 LHQTLSNMVSQAQSHHEAPKSQEDTICTMFYYPQKIPNKPEFEDSNPSPLPPDMAPGQSY 1738
              Q   + VSQ +S H+   S+ +      Y  QK         S+ S  P   APG   
Sbjct: 89   APQDSDSEVSQNRSPHQESLSENNP--AQSYLTQK---------SSSSVSPSSNAPGSC- 136

Query: 1739 QPQSESASSSSMDKYHIHHISEPTRQENWTPLKNDLENHLEDFELEVELLITLIKSEKGS 1798
                +      +D +H   +++    E+ +    D  ++ + + +    LI +   E G 
Sbjct: 137  --SPDGVDQQLLDDFH--RVTKGGSTEDASQYYCDKNDNGDSYLV----LIRITPDEDGK 188

Query: 1799 LGFTVTKGNQRIGCYVHDVIQDPAKSDG---RLKPGDRLIKVNDTDVTNMTHTDAVNLLR 1855
             GF +  G  +    V   I   + +D    +L  GD+++ +N  D++  TH   V  ++
Sbjct: 189  FGFNLKGGVDQKMPLVVSRINPESPADTCIPKLNEGDQIVLINGRDISEHTHDQVVMFIK 248

Query: 1856 AA----SKTVRLVIGR 1867
            A+    S+ + LVI R
Sbjct: 249  ASRESHSRELALVIRR 264


>gi|223941888 protein tyrosine phosphatase, non-receptor type 3
            isoform 5 [Homo sapiens]
          Length = 626

 Score =  190 bits (482), Expect = 2e-47
 Identities = 110/299 (36%), Positives = 156/299 (52%), Gaps = 5/299 (1%)

Query: 2172 FLTNDELAVLPVVKVLPSGKYTGANLKSVIRVLRGLLDQGIPSKELENLQELKPLDQCLI 2231
            F + DEL  L    + P     G  L+  +  L+  L+ G    + E L   KP      
Sbjct: 318  FKSEDELNQLFPEAIFPMCPEGGDTLEGSMAQLKKGLESGTVLIQFEQLYRKKPGLAITF 377

Query: 2232 GQTKENRRKNRYKNILPYDATRVPLGDEGGYINASFIKIPVGKEEFV--YIACQGPLPTT 2289
             +  +N  KNRYK++LPYD TRV L     YINAS++ + +     V  YIA QGPLP T
Sbjct: 378  AKLPQNLDKNRYKDVLPYDTTRVLLQGNEDYINASYVNMEIPAANLVNKYIATQGPLPHT 437

Query: 2290 VGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSNRLRLALVRMQQLKG 2349
               FWQ++W+QK ++I M+T   E  + KC +YWP+      M      +          
Sbjct: 438  CAQFWQVVWDQKLSLIVMLTTLTERGRTKCHQYWPD--PPDVMNHGGFHIQCQSEDCTIA 495

Query: 2350 FVVRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYMRHIH-RSGPIITHC 2408
            +V R M + + QT E   ++HL + AWPDH  P    D L F++Y+R +   S P++ HC
Sbjct: 496  YVSREMLVTNTQTGEEHTVTHLQYVAWPDHGVPDDSSDFLEFVNYVRSLRVDSEPVLVHC 555

Query: 2409 SAGIGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTEDQYIFCYQVILYV 2467
            SAGIGR+G L+ ++  + L  ++L     D+VR MR QR  MVQT  QY F  + IL V
Sbjct: 556  SAGIGRTGVLVTMETAMCLTERNLPIYPLDIVRKMRDQRAMMVQTSSQYKFVCEAILRV 614



 Score = 38.9 bits (89), Expect = 0.064
 Identities = 58/269 (21%), Positives = 108/269 (40%), Gaps = 30/269 (11%)

Query: 1606 SPAQVLPNSSKDSSQPSCVEQSTSSDENEMSDKSKKQCKSPSRRDSYSDSSGSGEDDLVT 1665
            +PA     S +     S   +S     N  S + + + + P  R S +D+  + E   +T
Sbjct: 64   NPAMRRSLSVEHLETKSLPSRSPPITPNWRSPRLRHEIRKP--RHSSADNLAN-EMTYIT 120

Query: 1666 APANISNSTWSSALHQTLSNMVSQAQSHHEAPKSQEDTICTMFYYPQKIPNKPEFEDSNP 1725
               ++  +   S   Q   + VSQ +S H+   S+ +      Y  QK         S+ 
Sbjct: 121  ETEDVFYTYKGSLAPQDSDSEVSQNRSPHQESLSENNP--AQSYLTQK---------SSS 169

Query: 1726 SPLPPDMAPGQSYQPQSESASSSSMDKYHIHHISEPTRQENWTPLKNDLENHLEDFELEV 1785
            S  P   APG       +      +D +H   +++    E+ +    D  ++ + + +  
Sbjct: 170  SVSPSSNAPGSC---SPDGVDQQLLDDFH--RVTKGGSTEDASQYYCDKNDNGDSYLV-- 222

Query: 1786 ELLITLIKSEKGSLGFTVTKGNQRIGCYVHDVIQDPAKSDG---RLKPGDRLIKVNDTDV 1842
              LI +   E G  GF +  G  +    V   I   + +D    +L  GD+++ +N  D+
Sbjct: 223  --LIRITPDEDGKFGFNLKGGVDQKMPLVVSRINPESPADTCIPKLNEGDQIVLINGRDI 280

Query: 1843 TNMTHTDAVNLLRAA----SKTVRLVIGR 1867
            +  TH   V  ++A+    S+ + LVI R
Sbjct: 281  SEHTHDQVVMFIKASRESHSRELALVIRR 309


>gi|223941885 protein tyrosine phosphatase, non-receptor type 3
            isoform 4 [Homo sapiens]
          Length = 737

 Score =  190 bits (482), Expect = 2e-47
 Identities = 110/299 (36%), Positives = 156/299 (52%), Gaps = 5/299 (1%)

Query: 2172 FLTNDELAVLPVVKVLPSGKYTGANLKSVIRVLRGLLDQGIPSKELENLQELKPLDQCLI 2231
            F + DEL  L    + P     G  L+  +  L+  L+ G    + E L   KP      
Sbjct: 429  FKSEDELNQLFPEAIFPMCPEGGDTLEGSMAQLKKGLESGTVLIQFEQLYRKKPGLAITF 488

Query: 2232 GQTKENRRKNRYKNILPYDATRVPLGDEGGYINASFIKIPVGKEEFV--YIACQGPLPTT 2289
             +  +N  KNRYK++LPYD TRV L     YINAS++ + +     V  YIA QGPLP T
Sbjct: 489  AKLPQNLDKNRYKDVLPYDTTRVLLQGNEDYINASYVNMEIPAANLVNKYIATQGPLPHT 548

Query: 2290 VGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSNRLRLALVRMQQLKG 2349
               FWQ++W+QK ++I M+T   E  + KC +YWP+      M      +          
Sbjct: 549  CAQFWQVVWDQKLSLIVMLTTLTERGRTKCHQYWPD--PPDVMNHGGFHIQCQSEDCTIA 606

Query: 2350 FVVRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYMRHIH-RSGPIITHC 2408
            +V R M + + QT E   ++HL + AWPDH  P    D L F++Y+R +   S P++ HC
Sbjct: 607  YVSREMLVTNTQTGEEHTVTHLQYVAWPDHGVPDDSSDFLEFVNYVRSLRVDSEPVLVHC 666

Query: 2409 SAGIGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTEDQYIFCYQVILYV 2467
            SAGIGR+G L+ ++  + L  ++L     D+VR MR QR  MVQT  QY F  + IL V
Sbjct: 667  SAGIGRTGVLVTMETAMCLTERNLPIYPLDIVRKMRDQRAMMVQTSSQYKFVCEAILRV 725



 Score = 76.3 bits (186), Expect = 4e-13
 Identities = 99/492 (20%), Positives = 184/492 (37%), Gaps = 93/492 (18%)

Query: 686  DILEERMHCDDETSLLLASLALQAEYGDYQPEVHGVSYFRMEHYLPARVMEKLDLSYIKE 745
            DI E R+ C   ++++LAS A+Q+ +GDY   +H   Y    H++P +  + L       
Sbjct: 2    DICEGRLTCPLNSAVVLASYAVQSHFGDYNSSIHHPGYLSDSHFIPDQNEDFL------T 55

Query: 746  ELPKLHNTYVGASEKETELEFLKVCQRLTEYGVHFHRVHPEKKSQTGILLGVCSKGVLVF 805
            ++  LH  + G  + E E  ++ + + L  YGV  H           +++G+ S GV V+
Sbjct: 56   KVESLHEQHSGLKQSEAESCYINIARTLDFYGVELH--SGRDLHNLDLMIGIASAGVAVY 113

Query: 806  EVHNGVRTLVLRFPWRETKKISFSKKKITL---QNTSDGIKH--GFQTDNSKICQYLLHL 860
              +         +PW    KISF +KK  +   Q  ++  +H   F   N + C+ L   
Sbjct: 114  RKY----ICTSFYPWVNILKISFKRKKFFIHQRQKQAESREHIVAFNMLNYRSCKNLWKS 169

Query: 861  CSYQHKFQLQMRARQSNQDAQDIERASFRSLNLQAESVRGFNMGRAISTGSLASSTLNKL 920
            C   H F                          QA+ +            ++ S    K 
Sbjct: 170  CVEHHTF-------------------------FQAKKLLPQEKNVLSQYWTMGSRNTKKR 204

Query: 921  AVRPLSVQAEILKRLSCSELSLYQPLQNSSKEKNDKASWEEKPREMSKSYHDLSQASLYP 980
            + R   ++ EI K           P  +S+    ++ ++  +  ++  +Y    + SL P
Sbjct: 205  SPR---LRHEIRK-----------PRHSSADNLANEMTYITETEDVFYTY----KGSLAP 246

Query: 981  HRKNVIVNMEPPPQTVAELVGKPSHQMSRSDAESLAGVTKLNNSKSVASLNRSPERRKHE 1040
               +  V+    P           HQ S S+           +S SV+  + +P     +
Sbjct: 247  QDSDSEVSQNRSP-----------HQESLSENNPAQSYLTQKSSSSVSPSSNAPGSCSPD 295

Query: 1041 SDSSSIEDPGQAYVLGMTMHSSGNSSSQVPLKENDVLHKRWSIVSSPEREITLVNLKKDA 1100
                 + D        +T   S   +SQ    +ND          + +  + L+ +  D 
Sbjct: 296  GVDQQLLDDFHR----VTKGGSTEDASQYYCDKND----------NGDSYLVLIRITPDE 341

Query: 1101 KYGLGFQIIGGEKMGRLDLGIFISSVAPGGPADLDGC---LKPGDRLISVNSVSLEGVSH 1157
                GF + GG       + + +S + P  PAD   C   L  GD+++ +N   +   +H
Sbjct: 342  DGKFGFNLKGGVDQ---KMPLVVSRINPESPADT--CIPKLNEGDQIVLINGRDISEHTH 396

Query: 1158 HAAIEILQNAPE 1169
               +  ++ + E
Sbjct: 397  DQVVMFIKASRE 408



 Score = 39.7 bits (91), Expect = 0.037
 Identities = 56/256 (21%), Positives = 103/256 (40%), Gaps = 34/256 (13%)

Query: 1625 EQSTSSDENEMSDKSKKQCKSPSRRDSYSDSSGSGEDDL------VTAPANISNSTWSSA 1678
            E++  S    M  ++ K+ +SP  R        S  D+L      +T   ++  +   S 
Sbjct: 186  EKNVLSQYWTMGSRNTKK-RSPRLRHEIRKPRHSSADNLANEMTYITETEDVFYTYKGSL 244

Query: 1679 LHQTLSNMVSQAQSHHEAPKSQEDTICTMFYYPQKIPNKPEFEDSNPSPLPPDMAPGQSY 1738
              Q   + VSQ +S H+   S+ +      Y  QK         S+ S  P   APG   
Sbjct: 245  APQDSDSEVSQNRSPHQESLSENNP--AQSYLTQK---------SSSSVSPSSNAPGSC- 292

Query: 1739 QPQSESASSSSMDKYHIHHISEPTRQENWTPLKNDLENHLEDFELEVELLITLIKSEKGS 1798
                +      +D +H   +++    E+ +    D  ++ + + +    LI +   E G 
Sbjct: 293  --SPDGVDQQLLDDFH--RVTKGGSTEDASQYYCDKNDNGDSYLV----LIRITPDEDGK 344

Query: 1799 LGFTVTKGNQRIGCYVHDVIQDPAKSDG---RLKPGDRLIKVNDTDVTNMTHTDAVNLLR 1855
             GF +  G  +    V   I   + +D    +L  GD+++ +N  D++  TH   V  ++
Sbjct: 345  FGFNLKGGVDQKMPLVVSRINPESPADTCIPKLNEGDQIVLINGRDISEHTHDQVVMFIK 404

Query: 1856 AA----SKTVRLVIGR 1867
            A+    S+ + LVI R
Sbjct: 405  ASRESHSRELALVIRR 420


>gi|223941882 protein tyrosine phosphatase, non-receptor type 3
            isoform 3 [Homo sapiens]
          Length = 782

 Score =  190 bits (482), Expect = 2e-47
 Identities = 110/299 (36%), Positives = 156/299 (52%), Gaps = 5/299 (1%)

Query: 2172 FLTNDELAVLPVVKVLPSGKYTGANLKSVIRVLRGLLDQGIPSKELENLQELKPLDQCLI 2231
            F + DEL  L    + P     G  L+  +  L+  L+ G    + E L   KP      
Sbjct: 474  FKSEDELNQLFPEAIFPMCPEGGDTLEGSMAQLKKGLESGTVLIQFEQLYRKKPGLAITF 533

Query: 2232 GQTKENRRKNRYKNILPYDATRVPLGDEGGYINASFIKIPVGKEEFV--YIACQGPLPTT 2289
             +  +N  KNRYK++LPYD TRV L     YINAS++ + +     V  YIA QGPLP T
Sbjct: 534  AKLPQNLDKNRYKDVLPYDTTRVLLQGNEDYINASYVNMEIPAANLVNKYIATQGPLPHT 593

Query: 2290 VGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSNRLRLALVRMQQLKG 2349
               FWQ++W+QK ++I M+T   E  + KC +YWP+      M      +          
Sbjct: 594  CAQFWQVVWDQKLSLIVMLTTLTERGRTKCHQYWPD--PPDVMNHGGFHIQCQSEDCTIA 651

Query: 2350 FVVRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYMRHIH-RSGPIITHC 2408
            +V R M + + QT E   ++HL + AWPDH  P    D L F++Y+R +   S P++ HC
Sbjct: 652  YVSREMLVTNTQTGEEHTVTHLQYVAWPDHGVPDDSSDFLEFVNYVRSLRVDSEPVLVHC 711

Query: 2409 SAGIGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTEDQYIFCYQVILYV 2467
            SAGIGR+G L+ ++  + L  ++L     D+VR MR QR  MVQT  QY F  + IL V
Sbjct: 712  SAGIGRTGVLVTMETAMCLTERNLPIYPLDIVRKMRDQRAMMVQTSSQYKFVCEAILRV 770



 Score = 82.4 bits (202), Expect = 5e-15
 Identities = 103/501 (20%), Positives = 197/501 (39%), Gaps = 66/501 (13%)

Query: 686  DILEERMHCDDETSLLLASLALQAEYGDYQPEVHGVSYFRMEHYLPARVMEKLDLSYIKE 745
            DI E R+ C   ++++LAS A+Q+ +GDY   +H   Y    H++P +  + L       
Sbjct: 2    DICEGRLTCPLNSAVVLASYAVQSHFGDYNSSIHHPGYLSDSHFIPDQNEDFL------T 55

Query: 746  ELPKLHNTYVGASEKETELEFLKVCQRLTEYGVHFHRVHPEKKSQTGILLGVCSKGVLVF 805
            ++  LH  + G  + E E  ++ + + L  YGV  H           +++G+ S GV V+
Sbjct: 56   KVESLHEQHSGLKQSEAESCYINIARTLDFYGVELH--SGRDLHNLDLMIGIASAGVAVY 113

Query: 806  EVHNGVRTLVLRFPWRETKKISFSKKKITL---QNTSDGIKH--GFQTDNSKICQYLLHL 860
              +         +PW    KISF +KK  +   Q  ++  +H   F   N + C+ L   
Sbjct: 114  RKY----ICTSFYPWVNILKISFKRKKFFIHQRQKQAESREHIVAFNMLNYRSCKNLWKS 169

Query: 861  CSYQHKFQLQMRARQSNQDAQDI--------ERASFRSLNLQ-AESVRGFNMGRAISTGS 911
            C   H F    +A++     +++         R + +S+N Q  + V G  +       S
Sbjct: 170  CVEHHTF---FQAKKLLPQEKNVLSQYWTMGSRNTKKSVNNQYCKKVIGGMVWNPAMRRS 226

Query: 912  LASSTLNKLAVRPLSVQAEILKRLSCSELSLYQPLQNSSKEKNDKASWEEKPREMSKSYH 971
            L+   L   ++   S       R       + +P  +S+    ++ ++  +  ++  +Y 
Sbjct: 227  LSVEHLETKSLPSRSPPITPNWRSPRLRHEIRKPRHSSADNLANEMTYITETEDVFYTY- 285

Query: 972  DLSQASLYPHRKNVIVNMEPPPQTVAELVGKPSHQMSRSDAESLAGVTKLNNSKSVASLN 1031
               + SL P   +  V+    P           HQ S S+           +S SV+  +
Sbjct: 286  ---KGSLAPQDSDSEVSQNRSP-----------HQESLSENNPAQSYLTQKSSSSVSPSS 331

Query: 1032 RSPERRKHESDSSSIEDPGQAYVLGMTMHSSGNSSSQVPLKENDVLHKRWSIVSSPEREI 1091
             +P     +     + D        +T   S   +SQ    +ND          + +  +
Sbjct: 332  NAPGSCSPDGVDQQLLDDFHR----VTKGGSTEDASQYYCDKND----------NGDSYL 377

Query: 1092 TLVNLKKDAKYGLGFQIIGGEKMGRLDLGIFISSVAPGGPADLDGC---LKPGDRLISVN 1148
             L+ +  D     GF + GG       + + +S + P  PAD   C   L  GD+++ +N
Sbjct: 378  VLIRITPDEDGKFGFNLKGGVDQ---KMPLVVSRINPESPADT--CIPKLNEGDQIVLIN 432

Query: 1149 SVSLEGVSHHAAIEILQNAPE 1169
               +   +H   +  ++ + E
Sbjct: 433  GRDISEHTHDQVVMFIKASRE 453



 Score = 38.9 bits (89), Expect = 0.064
 Identities = 58/269 (21%), Positives = 108/269 (40%), Gaps = 30/269 (11%)

Query: 1606 SPAQVLPNSSKDSSQPSCVEQSTSSDENEMSDKSKKQCKSPSRRDSYSDSSGSGEDDLVT 1665
            +PA     S +     S   +S     N  S + + + + P  R S +D+  + E   +T
Sbjct: 220  NPAMRRSLSVEHLETKSLPSRSPPITPNWRSPRLRHEIRKP--RHSSADNLAN-EMTYIT 276

Query: 1666 APANISNSTWSSALHQTLSNMVSQAQSHHEAPKSQEDTICTMFYYPQKIPNKPEFEDSNP 1725
               ++  +   S   Q   + VSQ +S H+   S+ +      Y  QK         S+ 
Sbjct: 277  ETEDVFYTYKGSLAPQDSDSEVSQNRSPHQESLSENNP--AQSYLTQK---------SSS 325

Query: 1726 SPLPPDMAPGQSYQPQSESASSSSMDKYHIHHISEPTRQENWTPLKNDLENHLEDFELEV 1785
            S  P   APG       +      +D +H   +++    E+ +    D  ++ + + +  
Sbjct: 326  SVSPSSNAPGSC---SPDGVDQQLLDDFH--RVTKGGSTEDASQYYCDKNDNGDSYLV-- 378

Query: 1786 ELLITLIKSEKGSLGFTVTKGNQRIGCYVHDVIQDPAKSDG---RLKPGDRLIKVNDTDV 1842
              LI +   E G  GF +  G  +    V   I   + +D    +L  GD+++ +N  D+
Sbjct: 379  --LIRITPDEDGKFGFNLKGGVDQKMPLVVSRINPESPADTCIPKLNEGDQIVLINGRDI 436

Query: 1843 TNMTHTDAVNLLRAA----SKTVRLVIGR 1867
            +  TH   V  ++A+    S+ + LVI R
Sbjct: 437  SEHTHDQVVMFIKASRESHSRELALVIRR 465


>gi|223941879 protein tyrosine phosphatase, non-receptor type 3
            isoform 2 [Homo sapiens]
          Length = 868

 Score =  190 bits (482), Expect = 2e-47
 Identities = 110/299 (36%), Positives = 156/299 (52%), Gaps = 5/299 (1%)

Query: 2172 FLTNDELAVLPVVKVLPSGKYTGANLKSVIRVLRGLLDQGIPSKELENLQELKPLDQCLI 2231
            F + DEL  L    + P     G  L+  +  L+  L+ G    + E L   KP      
Sbjct: 560  FKSEDELNQLFPEAIFPMCPEGGDTLEGSMAQLKKGLESGTVLIQFEQLYRKKPGLAITF 619

Query: 2232 GQTKENRRKNRYKNILPYDATRVPLGDEGGYINASFIKIPVGKEEFV--YIACQGPLPTT 2289
             +  +N  KNRYK++LPYD TRV L     YINAS++ + +     V  YIA QGPLP T
Sbjct: 620  AKLPQNLDKNRYKDVLPYDTTRVLLQGNEDYINASYVNMEIPAANLVNKYIATQGPLPHT 679

Query: 2290 VGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSNRLRLALVRMQQLKG 2349
               FWQ++W+QK ++I M+T   E  + KC +YWP+      M      +          
Sbjct: 680  CAQFWQVVWDQKLSLIVMLTTLTERGRTKCHQYWPD--PPDVMNHGGFHIQCQSEDCTIA 737

Query: 2350 FVVRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYMRHIH-RSGPIITHC 2408
            +V R M + + QT E   ++HL + AWPDH  P    D L F++Y+R +   S P++ HC
Sbjct: 738  YVSREMLVTNTQTGEEHTVTHLQYVAWPDHGVPDDSSDFLEFVNYVRSLRVDSEPVLVHC 797

Query: 2409 SAGIGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTEDQYIFCYQVILYV 2467
            SAGIGR+G L+ ++  + L  ++L     D+VR MR QR  MVQT  QY F  + IL V
Sbjct: 798  SAGIGRTGVLVTMETAMCLTERNLPIYPLDIVRKMRDQRAMMVQTSSQYKFVCEAILRV 856



 Score =  113 bits (282), Expect = 3e-24
 Identities = 128/584 (21%), Positives = 225/584 (38%), Gaps = 109/584 (18%)

Query: 597  VFDMVVAHIGLVEHHLFALATLKDNEYFFVDPDLKLTKVAPEGWKEEPK---KKTKATVN 653
            + DMV  H+G+ E   F L    D+             V    W E  K   K+ K    
Sbjct: 54   LLDMVHNHLGVTEKEYFGLQHDDDS-------------VDSPRWLEASKAIRKQLKGGFP 100

Query: 654  FTLFFRIKFFMDDVSLIQHTLTCHQYYLQLRKDILEERMHCDDETSLLLASLALQAEYGD 713
             TL FR++FF+ D + +Q   T H Y+LQL+ DI E R+ C   ++++LAS A+Q+ +GD
Sbjct: 101  CTLHFRVRFFIPDPNTLQQEQTRHLYFLQLKMDICEGRLTCPLNSAVVLASYAVQSHFGD 160

Query: 714  YQPEVHGVSYFRMEHYLPARVMEKLDLSYIKEELPKLHNTYVGASEKETELEFLKVCQRL 773
            Y   +H   Y    H++P +  + L       ++  LH  + G  + E E  ++ + + L
Sbjct: 161  YNSSIHHPGYLSDSHFIPDQNEDFL------TKVESLHEQHSGLKQSEAESCYINIARTL 214

Query: 774  TEYGVHFHRVHPEKKSQTGILLGVCSKGVLVFEVHNGVRTLVLRFPWRETKKISFSKKKI 833
              YGV  H           +++G+ S GV V+  +         +PW    KISF +KK 
Sbjct: 215  DFYGVELH--SGRDLHNLDLMIGIASAGVAVYRKY----ICTSFYPWVNILKISFKRKKF 268

Query: 834  TL---QNTSDGIKH--GFQTDNSKICQYLLHLCSYQHKFQLQMRARQSNQDAQDIERASF 888
             +   Q  ++  +H   F   N + C+ L   C   H F                     
Sbjct: 269  FIHQRQKQAESREHIVAFNMLNYRSCKNLWKSCVEHHTF--------------------- 307

Query: 889  RSLNLQAESVRGFNMGRAISTGSLASSTLNKLAVRPLSVQAEILKRLSCSELSLYQPLQN 948
                 QA+ +            ++ S    K + R   ++ EI K           P  +
Sbjct: 308  ----FQAKKLLPQEKNVLSQYWTMGSRNTKKRSPR---LRHEIRK-----------PRHS 349

Query: 949  SSKEKNDKASWEEKPREMSKSYHDLSQASLYPHRKNVIVNMEPPPQTVAELVGKPSHQMS 1008
            S+    ++ ++  +  ++  +Y    + SL P   +  V+    P           HQ S
Sbjct: 350  SADNLANEMTYITETEDVFYTY----KGSLAPQDSDSEVSQNRSP-----------HQES 394

Query: 1009 RSDAESLAGVTKLNNSKSVASLNRSPERRKHESDSSSIEDPGQAYVLGMTMHSSGNSSSQ 1068
             S+           +S SV+  + +P     +     + D        +T   S   +SQ
Sbjct: 395  LSENNPAQSYLTQKSSSSVSPSSNAPGSCSPDGVDQQLLDDFHR----VTKGGSTEDASQ 450

Query: 1069 VPLKENDVLHKRWSIVSSPEREITLVNLKKDAKYGLGFQIIGGEKMGRLDLGIFISSVAP 1128
                +ND          + +  + L+ +  D     GF + GG       + + +S + P
Sbjct: 451  YYCDKND----------NGDSYLVLIRITPDEDGKFGFNLKGGVDQ---KMPLVVSRINP 497

Query: 1129 GGPADLDGC---LKPGDRLISVNSVSLEGVSHHAAIEILQNAPE 1169
              PAD   C   L  GD+++ +N   +   +H   +  ++ + E
Sbjct: 498  ESPADT--CIPKLNEGDQIVLINGRDISEHTHDQVVMFIKASRE 539



 Score = 39.7 bits (91), Expect = 0.037
 Identities = 56/256 (21%), Positives = 103/256 (40%), Gaps = 34/256 (13%)

Query: 1625 EQSTSSDENEMSDKSKKQCKSPSRRDSYSDSSGSGEDDL------VTAPANISNSTWSSA 1678
            E++  S    M  ++ K+ +SP  R        S  D+L      +T   ++  +   S 
Sbjct: 317  EKNVLSQYWTMGSRNTKK-RSPRLRHEIRKPRHSSADNLANEMTYITETEDVFYTYKGSL 375

Query: 1679 LHQTLSNMVSQAQSHHEAPKSQEDTICTMFYYPQKIPNKPEFEDSNPSPLPPDMAPGQSY 1738
              Q   + VSQ +S H+   S+ +      Y  QK         S+ S  P   APG   
Sbjct: 376  APQDSDSEVSQNRSPHQESLSENNP--AQSYLTQK---------SSSSVSPSSNAPGSC- 423

Query: 1739 QPQSESASSSSMDKYHIHHISEPTRQENWTPLKNDLENHLEDFELEVELLITLIKSEKGS 1798
                +      +D +H   +++    E+ +    D  ++ + + +    LI +   E G 
Sbjct: 424  --SPDGVDQQLLDDFH--RVTKGGSTEDASQYYCDKNDNGDSYLV----LIRITPDEDGK 475

Query: 1799 LGFTVTKGNQRIGCYVHDVIQDPAKSDG---RLKPGDRLIKVNDTDVTNMTHTDAVNLLR 1855
             GF +  G  +    V   I   + +D    +L  GD+++ +N  D++  TH   V  ++
Sbjct: 476  FGFNLKGGVDQKMPLVVSRINPESPADTCIPKLNEGDQIVLINGRDISEHTHDQVVMFIK 535

Query: 1856 AA----SKTVRLVIGR 1867
            A+    S+ + LVI R
Sbjct: 536  ASRESHSRELALVIRR 551


>gi|223941876 protein tyrosine phosphatase, non-receptor type 3
            isoform 1 [Homo sapiens]
          Length = 913

 Score =  190 bits (482), Expect = 2e-47
 Identities = 110/299 (36%), Positives = 156/299 (52%), Gaps = 5/299 (1%)

Query: 2172 FLTNDELAVLPVVKVLPSGKYTGANLKSVIRVLRGLLDQGIPSKELENLQELKPLDQCLI 2231
            F + DEL  L    + P     G  L+  +  L+  L+ G    + E L   KP      
Sbjct: 605  FKSEDELNQLFPEAIFPMCPEGGDTLEGSMAQLKKGLESGTVLIQFEQLYRKKPGLAITF 664

Query: 2232 GQTKENRRKNRYKNILPYDATRVPLGDEGGYINASFIKIPVGKEEFV--YIACQGPLPTT 2289
             +  +N  KNRYK++LPYD TRV L     YINAS++ + +     V  YIA QGPLP T
Sbjct: 665  AKLPQNLDKNRYKDVLPYDTTRVLLQGNEDYINASYVNMEIPAANLVNKYIATQGPLPHT 724

Query: 2290 VGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSNRLRLALVRMQQLKG 2349
               FWQ++W+QK ++I M+T   E  + KC +YWP+      M      +          
Sbjct: 725  CAQFWQVVWDQKLSLIVMLTTLTERGRTKCHQYWPD--PPDVMNHGGFHIQCQSEDCTIA 782

Query: 2350 FVVRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYMRHIH-RSGPIITHC 2408
            +V R M + + QT E   ++HL + AWPDH  P    D L F++Y+R +   S P++ HC
Sbjct: 783  YVSREMLVTNTQTGEEHTVTHLQYVAWPDHGVPDDSSDFLEFVNYVRSLRVDSEPVLVHC 842

Query: 2409 SAGIGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTEDQYIFCYQVILYV 2467
            SAGIGR+G L+ ++  + L  ++L     D+VR MR QR  MVQT  QY F  + IL V
Sbjct: 843  SAGIGRTGVLVTMETAMCLTERNLPIYPLDIVRKMRDQRAMMVQTSSQYKFVCEAILRV 901



 Score =  119 bits (298), Expect = 4e-26
 Identities = 132/593 (22%), Positives = 238/593 (40%), Gaps = 82/593 (13%)

Query: 597  VFDMVVAHIGLVEHHLFALATLKDNEYFFVDPDLKLTKVAPEGWKEEPK---KKTKATVN 653
            + DMV  H+G+ E   F L    D+             V    W E  K   K+ K    
Sbjct: 54   LLDMVHNHLGVTEKEYFGLQHDDDS-------------VDSPRWLEASKAIRKQLKGGFP 100

Query: 654  FTLFFRIKFFMDDVSLIQHTLTCHQYYLQLRKDILEERMHCDDETSLLLASLALQAEYGD 713
             TL FR++FF+ D + +Q   T H Y+LQL+ DI E R+ C   ++++LAS A+Q+ +GD
Sbjct: 101  CTLHFRVRFFIPDPNTLQQEQTRHLYFLQLKMDICEGRLTCPLNSAVVLASYAVQSHFGD 160

Query: 714  YQPEVHGVSYFRMEHYLPARVMEKLDLSYIKEELPKLHNTYVGASEKETELEFLKVCQRL 773
            Y   +H   Y    H++P +  + L       ++  LH  + G  + E E  ++ + + L
Sbjct: 161  YNSSIHHPGYLSDSHFIPDQNEDFL------TKVESLHEQHSGLKQSEAESCYINIARTL 214

Query: 774  TEYGVHFHRVHPEKKSQTGILLGVCSKGVLVFEVHNGVRTLVLRFPWRETKKISFSKKKI 833
              YGV  H           +++G+ S GV V+  +         +PW    KISF +KK 
Sbjct: 215  DFYGVELH--SGRDLHNLDLMIGIASAGVAVYRKY----ICTSFYPWVNILKISFKRKKF 268

Query: 834  TL---QNTSDGIKH--GFQTDNSKICQYLLHLCSYQHKFQLQMRARQSNQDAQDI----- 883
             +   Q  ++  +H   F   N + C+ L   C   H F    +A++     +++     
Sbjct: 269  FIHQRQKQAESREHIVAFNMLNYRSCKNLWKSCVEHHTF---FQAKKLLPQEKNVLSQYW 325

Query: 884  ---ERASFRSLNLQ-AESVRGFNMGRAISTGSLASSTLNKLAVRPLSVQAEILKRLSCSE 939
                R + +S+N Q  + V G  +       SL+   L   ++   S       R     
Sbjct: 326  TMGSRNTKKSVNNQYCKKVIGGMVWNPAMRRSLSVEHLETKSLPSRSPPITPNWRSPRLR 385

Query: 940  LSLYQPLQNSSKEKNDKASWEEKPREMSKSYHDLSQASLYPHRKNVIVNMEPPPQTVAEL 999
              + +P  +S+    ++ ++  +  ++  +Y    + SL P   +  V+    P      
Sbjct: 386  HEIRKPRHSSADNLANEMTYITETEDVFYTY----KGSLAPQDSDSEVSQNRSP------ 435

Query: 1000 VGKPSHQMSRSDAESLAGVTKLNNSKSVASLNRSPERRKHESDSSSIEDPGQAYVLGMTM 1059
                 HQ S S+           +S SV+  + +P     +     + D        +T 
Sbjct: 436  -----HQESLSENNPAQSYLTQKSSSSVSPSSNAPGSCSPDGVDQQLLDDFHR----VTK 486

Query: 1060 HSSGNSSSQVPLKENDVLHKRWSIVSSPEREITLVNLKKDAKYGLGFQIIGGEKMGRLDL 1119
              S   +SQ    +ND          + +  + L+ +  D     GF + GG       +
Sbjct: 487  GGSTEDASQYYCDKND----------NGDSYLVLIRITPDEDGKFGFNLKGGVDQ---KM 533

Query: 1120 GIFISSVAPGGPADLDGC---LKPGDRLISVNSVSLEGVSHHAAIEILQNAPE 1169
             + +S + P  PAD   C   L  GD+++ +N   +   +H   +  ++ + E
Sbjct: 534  PLVVSRINPESPADT--CIPKLNEGDQIVLINGRDISEHTHDQVVMFIKASRE 584



 Score = 38.9 bits (89), Expect = 0.064
 Identities = 58/269 (21%), Positives = 108/269 (40%), Gaps = 30/269 (11%)

Query: 1606 SPAQVLPNSSKDSSQPSCVEQSTSSDENEMSDKSKKQCKSPSRRDSYSDSSGSGEDDLVT 1665
            +PA     S +     S   +S     N  S + + + + P  R S +D+  + E   +T
Sbjct: 351  NPAMRRSLSVEHLETKSLPSRSPPITPNWRSPRLRHEIRKP--RHSSADNLAN-EMTYIT 407

Query: 1666 APANISNSTWSSALHQTLSNMVSQAQSHHEAPKSQEDTICTMFYYPQKIPNKPEFEDSNP 1725
               ++  +   S   Q   + VSQ +S H+   S+ +      Y  QK         S+ 
Sbjct: 408  ETEDVFYTYKGSLAPQDSDSEVSQNRSPHQESLSENNP--AQSYLTQK---------SSS 456

Query: 1726 SPLPPDMAPGQSYQPQSESASSSSMDKYHIHHISEPTRQENWTPLKNDLENHLEDFELEV 1785
            S  P   APG       +      +D +H   +++    E+ +    D  ++ + + +  
Sbjct: 457  SVSPSSNAPGSC---SPDGVDQQLLDDFH--RVTKGGSTEDASQYYCDKNDNGDSYLV-- 509

Query: 1786 ELLITLIKSEKGSLGFTVTKGNQRIGCYVHDVIQDPAKSDG---RLKPGDRLIKVNDTDV 1842
              LI +   E G  GF +  G  +    V   I   + +D    +L  GD+++ +N  D+
Sbjct: 510  --LIRITPDEDGKFGFNLKGGVDQKMPLVVSRINPESPADTCIPKLNEGDQIVLINGRDI 567

Query: 1843 TNMTHTDAVNLLRAA----SKTVRLVIGR 1867
            +  TH   V  ++A+    S+ + LVI R
Sbjct: 568  SEHTHDQVVMFIKASRESHSRELALVIRR 596


>gi|33356177 protein tyrosine phosphatase, non-receptor type 11 [Homo
            sapiens]
          Length = 593

 Score =  189 bits (480), Expect = 3e-47
 Identities = 125/330 (37%), Positives = 175/330 (53%), Gaps = 31/330 (9%)

Query: 2180 VLPVVKVLPSGKYTGANLKSVIRVLRGLLDQGIPSK-----ELENLQ--ELKPLDQCLIG 2232
            VL + + L + +   A ++S +R L  L +     K     E E LQ  E K L     G
Sbjct: 209  VLQLKQPLNTTRINAAEIESRVRELSKLAETTDKVKQGFWEEFETLQQQECKLLYSRKEG 268

Query: 2233 QTKENRRKNRYKNILPYDATRVPLGDE------GGYINASFI------KIPVGKEEFVYI 2280
            Q +EN+ KNRYKNILP+D TRV L D         YINA+ I      K    K +  YI
Sbjct: 269  QRQENKNKNRYKNILPFDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYI 328

Query: 2281 ACQGPLPTTVGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSNRLRLA 2340
            A QG L  TV DFW+M++++ S VI M T+EVE  K KC +YWP+           +R+ 
Sbjct: 329  ATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEY--GVMRVR 386

Query: 2341 LVRMQQLKGFVVRAMTLEDI-QTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYMRH-- 2397
             V+      + +R + L  + Q    R +   +F  WPDH  PS P  +L F+  + H  
Sbjct: 387  NVKESAAHDYTLRELKLSKVGQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQ 446

Query: 2398 --IHRSGPIITHCSAGIGRSGTLICIDVVLGLISQ---DLDFDISDLVRCMRLQRHGMVQ 2452
              I  +GP++ HCSAGIGR+GT I ID+++ +I +   D D D+   ++ +R QR GMVQ
Sbjct: 447  ESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQ 506

Query: 2453 TEDQYIFCYQVILYVLTRLQ--AEEEQKQQ 2480
            TE QY F Y  + + +  LQ   EEEQK +
Sbjct: 507  TEAQYRFIYMAVQHYIETLQRRIEEEQKSK 536


>gi|4506295 protein tyrosine phosphatase, non-receptor type 4 [Homo
            sapiens]
          Length = 926

 Score =  186 bits (473), Expect = 2e-46
 Identities = 104/275 (37%), Positives = 156/275 (56%), Gaps = 9/275 (3%)

Query: 2198 KSVIRVLRGLLDQGIPSKELENLQELKPLDQCLIGQTKENRRKNRYKNILPYDATRVPLG 2257
            +S+I++  GL+  G    + + L   KP       +  +N  KNRY++I PYDATRV L 
Sbjct: 641  ESMIQLAEGLIT-GTVLTQFDQLYRKKPGMTMSCAKLPQNISKNRYRDISPYDATRVILK 699

Query: 2258 DEGGYINASFIKIPVGKEEFV--YIACQGPLPTTVGDFWQMIWEQKSTVIAMMTQEVEGE 2315
                YINA++I + +     +  YIACQGPLP T  DFWQM WEQ S+++ M+T +VE  
Sbjct: 700  GNEDYINANYINMEIPSSSIINQYIACQGPLPHTCTDFWQMTWEQGSSMVVMLTTQVERG 759

Query: 2316 KIKCQRYWPNILGKTTMVSNRLRLALVRMQQLKGFVVRAMTLEDIQTREVRHISHLNFTA 2375
            ++KC +YWP   G ++      ++     +    ++ R MTL + +  E R ++ + + A
Sbjct: 760  RVKCHQYWPEPTGSSSY--GCYQVTCHSEEGNTAYIFRKMTLFNQEKNESRPLTQIQYIA 817

Query: 2376 WPDHDTPSQPDDLLTFISYMRHIHRSG---PIITHCSAGIGRSGTLICIDVVLGLISQDL 2432
            WPDH  P    D L F+ ++R+  R+G   P++ HCSAGIGR+G LI ++  + LI  + 
Sbjct: 818  WPDHGVPDDSSDFLDFVCHVRN-KRAGKEEPVVVHCSAGIGRTGVLITMETAMCLIECNQ 876

Query: 2433 DFDISDLVRCMRLQRHGMVQTEDQYIFCYQVILYV 2467
                 D+VR MR QR  M+QT  QY F  + IL V
Sbjct: 877  PVYPLDIVRTMRDQRAMMIQTPSQYRFVCEAILKV 911



 Score =  145 bits (365), Expect = 6e-34
 Identities = 172/683 (25%), Positives = 285/683 (41%), Gaps = 93/683 (13%)

Query: 575  NIMLLNGQRLELTCDTKTICKDVFDMVVAHIGLVEHHLFALATLKDN--EYFFVDPDLKL 632
            NI+LL+        +     + + D+V  H+ L E   F L    D+     ++DP+  +
Sbjct: 32   NILLLDNTVQAFKVNKHDQGQVLLDVVFKHLDLTEQDYFGLQLADDSTDNPRWLDPNKPI 91

Query: 633  TKVAPEGWKEEPKKKTKATVNFTLFFRIKFFMDDVSLIQHTLTCHQYYLQLRKDILEERM 692
                        +K+ K    ++L FR+KFF+ D + +Q   T +QY+LQ+++DIL  R+
Sbjct: 92   ------------RKQLKRGSPYSLNFRVKFFVSDPNKLQEEYTRYQYFLQIKQDILTGRL 139

Query: 693  HCDDETSLLLASLALQAEYGDYQPEVHGVSYFRMEHYLPARVMEKLDLSYIKEELPKLHN 752
             C   T+ LLAS A+Q+E GDY    +   Y     ++P +  +       ++E+ KLH 
Sbjct: 140  PCPSNTAALLASFAVQSELGDYDQSENLSGYLSDYSFIPNQPQD------FEKEIAKLHQ 193

Query: 753  TYVGASEKETELEFLKVCQRLTEYGVHFHRVHPEKKSQTGILLGVCSKGVLVFEVHNGVR 812
             ++G S  E E  +L   + L  YGV FH  +   +S   I++GV S G+L+++  N VR
Sbjct: 194  QHIGLSPAEAEFNYLNTARTLELYGVEFH--YARDQSNNEIMIGVMSGGILIYK--NRVR 249

Query: 813  TLVLRFPWRETKKISFSKKKITLQ-----NTSDGIKHGFQTDNSKICQYLLHLCSYQHKF 867
              +  FPW +  KISF  K+  +Q     + S     GF   N + C+ L   C   H F
Sbjct: 250  --MNTFPWLKIVKISFKCKQFFIQLRKELHESRETLLGFNMVNYRACKNLWKACVEHHTF 307

Query: 868  QLQMR--ARQSNQDAQDIERAS-FRSL-NLQAESVRGFNMGRAISTGSLASSTLNKLAVR 923
                R    Q N  A      S FR     + +SV+ +   +A      A S    LA +
Sbjct: 308  FRLDRPLPPQKNFFAHYFTLGSKFRYCGRTEVQSVQ-YGKEKANKDRVFARSPSKPLARK 366

Query: 924  PLSVQAEILKRLSCSELSLYQ---PLQNSSKEKNDKAS--WEEKPREMSKSYHDLSQASL 978
               +  E++ R S S+  L     P ++     N + S   +E  R    S   L    +
Sbjct: 367  --LMDWEVVSRNSISDDRLETQSLPSRSPPGTPNHRNSTFTQEGTRLRPSSVGHLVDHMV 424

Query: 979  YPHRKNVIVNMEPPPQTVAE---LVGKPSHQMSRSDAESLAGVTKLNNSKSVASLNRSPE 1035
            +     V VN   P  T A    L   PS Q +  D +  A   K +   S   ++ S  
Sbjct: 425  HTSPSEVFVNQRSPSSTQANSIVLESSPS-QETPGDGKPPALPPKQSKKNSWNQIHYSHS 483

Query: 1036 RRKHESDSSSIEDPGQAYVLGMTMHSSGNSSSQVPLKENDVLHKRWSIVSSPEREITLVN 1095
            ++  ES  +   D                SS + P     +          P   + L+ 
Sbjct: 484  QQDLESHINETFDI--------------PSSPEKPTPNGGI----------PHDNLVLIR 519

Query: 1096 LKKDAKYGLGFQIIGGEKMGRLDLGIFISSVAPGGPADLDGC---LKPGDRLISVNSVSL 1152
            +K D     GF + GG       + + +S VAPG PADL  C   L  GD+++ +N   +
Sbjct: 520  MKPDENGRFGFNVKGGYDQ---KMPVIVSRVAPGTPADL--CVPRLNEGDQVVLINGRDI 574

Query: 1153 EGVSHHAAIEILQNAPE----DVTLVISQPKEKISKVPSTPVHLTNEMKNYMKKSSYMQD 1208
               +H   +  ++ + E    ++ L++          P+    +  E         Y+ +
Sbjct: 575  AEHTHDQVVLFIKASCERHSGELMLLVR---------PNAVYDVVEEKLENEPDFQYIPE 625

Query: 1209 SA-IDSSSKDHHWSRGTLRHISE 1230
             A +DS  +D H  R ++  ++E
Sbjct: 626  KAPLDSVHQDDHSLRESMIQLAE 648



 Score = 39.7 bits (91), Expect = 0.037
 Identities = 33/146 (22%), Positives = 57/146 (39%), Gaps = 11/146 (7%)

Query: 1715 PNKPEFEDSNPSPLPPDMAPGQSYQPQSESASSSSMDKYHIHHISEPTRQENWTPLKNDL 1774
            P++    D  P  LPP  +   S+     S S   ++ +       P+  E  TP     
Sbjct: 452  PSQETPGDGKPPALPPKQSKKNSWNQIHYSHSQQDLESHINETFDIPSSPEKPTPNGGIP 511

Query: 1775 ENHLEDFELEVELLITLIKSEKGSLGFTVTKGNQRIGCYVHDVIQDPAKSD---GRLKPG 1831
             ++L        +LI +   E G  GF V  G  +    +   +     +D    RL  G
Sbjct: 512  HDNL--------VLIRMKPDENGRFGFNVKGGYDQKMPVIVSRVAPGTPADLCVPRLNEG 563

Query: 1832 DRLIKVNDTDVTNMTHTDAVNLLRAA 1857
            D+++ +N  D+   TH   V  ++A+
Sbjct: 564  DQVVLINGRDIAEHTHDQVVLFIKAS 589


>gi|109633041 protein tyrosine phosphatase, receptor type, F isoform 1
            precursor [Homo sapiens]
          Length = 1907

 Score =  183 bits (464), Expect = 2e-45
 Identities = 94/240 (39%), Positives = 140/240 (58%), Gaps = 12/240 (5%)

Query: 2237 NRRKNRYKNILPYDATRVPLGDEGG-----YINASFIKIPVGKEEFVYIACQGPLPTTVG 2291
            N+ KNRY N++ YD +RV L    G     YINA++I     +++  YIA QGPLP T+G
Sbjct: 1375 NKPKNRYANVIAYDHSRVILTSIDGVPGSDYINANYID--GYRKQNAYIATQGPLPETMG 1432

Query: 2292 DFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSNRLRLALVRMQQLKGFV 2351
            DFW+M+WEQ++  + MMT+  E  ++KC +YWP    + T     +++ L+   +L  + 
Sbjct: 1433 DFWRMVWEQRTATVVMMTRLEEKSRVKCDQYWP---ARGTETCGLIQVTLLDTVELATYT 1489

Query: 2352 VRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYMRHIHR--SGPIITHCS 2409
            VR   L    + E R +    F AWPDH  P  P  +L F+  ++  +   +GP++ HCS
Sbjct: 1490 VRTFALHKSGSSEKRELRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPLDAGPMVVHCS 1549

Query: 2410 AGIGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTEDQYIFCYQVILYVLT 2469
            AG+GR+G  I ID +L  +  +   DI   V CMR QR+ MVQTEDQY+F ++ +L   T
Sbjct: 1550 AGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAAT 1609



 Score =  150 bits (379), Expect = 2e-35
 Identities = 90/241 (37%), Positives = 127/241 (52%), Gaps = 14/241 (5%)

Query: 2237 NRRKNRYKNILPYDATRVPL----GDEGG-YINASFIKIPVGKEEFVYIACQGPLPTTVG 2291
            N+ KNR  NI+PY+ TRV L    G EG  YINASF+     +++  YIA QGPL  +  
Sbjct: 1664 NKFKNRLVNIMPYELTRVCLQPIRGVEGSDYINASFLD--GYRQQKAYIATQGPLAESTE 1721

Query: 2292 DFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSNRLRLALVRMQQLKGFV 2351
            DFW+M+WE  ST+I M+T+  E  + KC +YWP              +A   M Q   ++
Sbjct: 1722 DFWRMLWEHNSTIIVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQ---YI 1778

Query: 2352 VRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYMR----HIHRSGPIITH 2407
            +R   + D +  + R I    FT WP+   P   +  + FI  +        + GPI  H
Sbjct: 1779 LREFKVTDARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQFGQDGPITVH 1838

Query: 2408 CSAGIGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTEDQYIFCYQVILYV 2467
            CSAG+GR+G  I + +VL  +  +   D+   V+ +R QR  MVQTEDQY  CY+  L  
Sbjct: 1839 CSAGVGRTGVFITLSIVLERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEY 1898

Query: 2468 L 2468
            L
Sbjct: 1899 L 1899


>gi|109633039 protein tyrosine phosphatase, receptor type, F isoform 2
            precursor [Homo sapiens]
          Length = 1898

 Score =  183 bits (464), Expect = 2e-45
 Identities = 94/240 (39%), Positives = 140/240 (58%), Gaps = 12/240 (5%)

Query: 2237 NRRKNRYKNILPYDATRVPLGDEGG-----YINASFIKIPVGKEEFVYIACQGPLPTTVG 2291
            N+ KNRY N++ YD +RV L    G     YINA++I     +++  YIA QGPLP T+G
Sbjct: 1366 NKPKNRYANVIAYDHSRVILTSIDGVPGSDYINANYID--GYRKQNAYIATQGPLPETMG 1423

Query: 2292 DFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSNRLRLALVRMQQLKGFV 2351
            DFW+M+WEQ++  + MMT+  E  ++KC +YWP    + T     +++ L+   +L  + 
Sbjct: 1424 DFWRMVWEQRTATVVMMTRLEEKSRVKCDQYWP---ARGTETCGLIQVTLLDTVELATYT 1480

Query: 2352 VRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYMRHIHR--SGPIITHCS 2409
            VR   L    + E R +    F AWPDH  P  P  +L F+  ++  +   +GP++ HCS
Sbjct: 1481 VRTFALHKSGSSEKRELRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPLDAGPMVVHCS 1540

Query: 2410 AGIGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTEDQYIFCYQVILYVLT 2469
            AG+GR+G  I ID +L  +  +   DI   V CMR QR+ MVQTEDQY+F ++ +L   T
Sbjct: 1541 AGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAAT 1600



 Score =  150 bits (379), Expect = 2e-35
 Identities = 90/241 (37%), Positives = 127/241 (52%), Gaps = 14/241 (5%)

Query: 2237 NRRKNRYKNILPYDATRVPL----GDEGG-YINASFIKIPVGKEEFVYIACQGPLPTTVG 2291
            N+ KNR  NI+PY+ TRV L    G EG  YINASF+     +++  YIA QGPL  +  
Sbjct: 1655 NKFKNRLVNIMPYELTRVCLQPIRGVEGSDYINASFLD--GYRQQKAYIATQGPLAESTE 1712

Query: 2292 DFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSNRLRLALVRMQQLKGFV 2351
            DFW+M+WE  ST+I M+T+  E  + KC +YWP              +A   M Q   ++
Sbjct: 1713 DFWRMLWEHNSTIIVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQ---YI 1769

Query: 2352 VRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYMR----HIHRSGPIITH 2407
            +R   + D +  + R I    FT WP+   P   +  + FI  +        + GPI  H
Sbjct: 1770 LREFKVTDARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQFGQDGPITVH 1829

Query: 2408 CSAGIGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTEDQYIFCYQVILYV 2467
            CSAG+GR+G  I + +VL  +  +   D+   V+ +R QR  MVQTEDQY  CY+  L  
Sbjct: 1830 CSAGVGRTGVFITLSIVLERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEY 1889

Query: 2468 L 2468
            L
Sbjct: 1890 L 1890


>gi|208431815 protein tyrosine phosphatase, receptor type, K isoform a
            [Homo sapiens]
          Length = 1446

 Score =  182 bits (462), Expect = 4e-45
 Identities = 100/246 (40%), Positives = 148/246 (60%), Gaps = 15/246 (6%)

Query: 2231 IGQTKENRRKNRYKNILPYDATRV---PLGDE--GGYINASFIKIPVGKEEFV----YIA 2281
            + +  +NR KNRY NI+ YD +RV   P+ D+    YINA++I I + ++ +     YIA
Sbjct: 905  VAKKDQNRAKNRYGNIIAYDHSRVILQPVEDDPSSDYINANYIDIWLYRDGYQRPSHYIA 964

Query: 2282 CQGPLPTTVGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSNRLRLAL 2341
             QGP+  TV DFW+MIW+++S  I M+T  VE  ++KC +YWP+     T V    ++  
Sbjct: 965  TQGPVHETVYDFWRMIWQEQSACIVMVTNLVEVGRVKCYKYWPD----DTEVYGDFKVTC 1020

Query: 2342 VRMQQLKGFVVRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYMRHIH-- 2399
            V M+ L  +VVR  TLE     E+R +   +FT WPDH  P     LL+FI  ++  +  
Sbjct: 1021 VEMEPLAEYVVRTFTLERRGYNEIREVKQFHFTGWPDHGVPYHATGLLSFIRRVKLSNPP 1080

Query: 2400 RSGPIITHCSAGIGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTEDQYIF 2459
             +GPI+ HCSAG GR+G  I ID++L +  ++   DI + V+ +R +R  MVQTE+QYIF
Sbjct: 1081 SAGPIVVHCSAGAGRTGCYIVIDIMLDMAEREGVVDIYNCVKALRSRRINMVQTEEQYIF 1140

Query: 2460 CYQVIL 2465
             +  IL
Sbjct: 1141 IHDAIL 1146



 Score = 84.7 bits (208), Expect = 1e-15
 Identities = 71/274 (25%), Positives = 114/274 (41%), Gaps = 34/274 (12%)

Query: 2216 ELENLQELKP---LDQCLIGQTKENRRKNRYKNILPYDATRVPL----GDEGGYINASFI 2268
            E + L  + P    + C I     N  KNR+ ++LP D     L    G+   YINA+ +
Sbjct: 1183 EFQTLNSVTPRLQAEDCSIACLPRNHDKNRFMDMLPPDRCLPFLITIDGESSNYINAALM 1242

Query: 2269 KIPVGKEEFVYIACQGPLPTTVGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILG 2328
                 ++   +I  Q PLP TV DFW+++++   T I M+  EV+  +  C +YWP    
Sbjct: 1243 DSY--RQPAAFIVTQYPLPNTVKDFWRLVYDYGCTSIVML-NEVDLSQ-GCPQYWPE--- 1295

Query: 2329 KTTMVSNRLRLALVRMQQLK--------GFVVRAMTLEDIQTREVRHISHLNFTAWPDH- 2379
                    LR   ++++ +           + R   L   Q   +  +    +  W  H 
Sbjct: 1296 -----EGMLRYGPIQVECMSCSMDCDVINRIFRICNLTRPQEGYLM-VQQFQYLGWASHR 1349

Query: 2380 DTPSQPDDLLTFISYMRHIHR-----SGPIITHCSAGIGRSGTLICIDVVLGLISQDLDF 2434
            + P      L  I  +           G  I HC  G GRSG    I +V+ ++ +    
Sbjct: 1350 EVPGSKRSFLKLILQVEKWQEECEEGEGRTIIHCLNGGGRSGMFCAIGIVVEMVKRQNVV 1409

Query: 2435 DISDLVRCMRLQRHGMVQTEDQYIFCYQVILYVL 2468
            D+   V+ +R  +  MV+  +QY FCY V L  L
Sbjct: 1410 DVFHAVKTLRNSKPNMVEAPEQYRFCYDVALEYL 1443


>gi|18104993 protein tyrosine phosphatase, non-receptor type 6 isoform
            3 [Homo sapiens]
          Length = 624

 Score =  182 bits (462), Expect = 4e-45
 Identities = 116/289 (40%), Positives = 160/289 (55%), Gaps = 23/289 (7%)

Query: 2215 KELENLQ--ELKPLDQCLIGQTKENRRKNRYKNILPYDATRVPLGDEGG------YINAS 2266
            +E E+LQ  E+K L Q L GQ  EN+ KNRYKNILP+D +RV L           YINA+
Sbjct: 246  EEFESLQKQEVKNLHQRLEGQRPENKGKNRYKNILPFDHSRVILQGRDSNIPGSDYINAN 305

Query: 2267 FIKIPV-GKEEFV--YIACQGPLPTTVGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYW 2323
            +IK  + G +E    YIA QG L  TV DFWQM W++ S VI M T+EVE  + KC  YW
Sbjct: 306  YIKNQLLGPDENAKTYIASQGCLEATVNDFWQMAWQENSRVIVMTTREVEKGRNKCVPYW 365

Query: 2324 PNILGKTTMVSNRLRLALVRMQQLKGFVVRAMTLEDIQTRE-VRHISHLNFTAWPDHDTP 2382
            P +            +          + +R + +  +   + +R I H  + +WPDH  P
Sbjct: 366  PEV--GMQRAYGPYSVTNCGEHDTTEYKLRTLQVSPLDNGDLIREIWHYQYLSWPDHGVP 423

Query: 2383 SQPDDLLTFISYMRH----IHRSGPIITHCSAGIGRSGTLICIDVVLGLISQ---DLDFD 2435
            S+P  +L+F+  +      +  +GPII HCSAGIGR+GT+I ID+++  IS    D D D
Sbjct: 424  SEPGGVLSFLDQINQRQESLPHAGPIIVHCSAGIGRTGTIIVIDMLMENISTKGLDCDID 483

Query: 2436 ISDLVRCMRLQRHGMVQTEDQYIFCYQVILYVL--TRLQAEEEQKQQPQ 2482
            I   ++ +R QR GMVQTE QY F Y  I   +  T+ + E  Q Q+ Q
Sbjct: 484  IQKTIQMVRAQRSGMVQTEAQYKFIYVAIAQFIETTKKKLEVLQSQKGQ 532


>gi|18104989 protein tyrosine phosphatase, non-receptor type 6 isoform
            1 [Homo sapiens]
          Length = 595

 Score =  182 bits (462), Expect = 4e-45
 Identities = 116/289 (40%), Positives = 160/289 (55%), Gaps = 23/289 (7%)

Query: 2215 KELENLQ--ELKPLDQCLIGQTKENRRKNRYKNILPYDATRVPLGDEGG------YINAS 2266
            +E E+LQ  E+K L Q L GQ  EN+ KNRYKNILP+D +RV L           YINA+
Sbjct: 246  EEFESLQKQEVKNLHQRLEGQRPENKGKNRYKNILPFDHSRVILQGRDSNIPGSDYINAN 305

Query: 2267 FIKIPV-GKEEFV--YIACQGPLPTTVGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYW 2323
            +IK  + G +E    YIA QG L  TV DFWQM W++ S VI M T+EVE  + KC  YW
Sbjct: 306  YIKNQLLGPDENAKTYIASQGCLEATVNDFWQMAWQENSRVIVMTTREVEKGRNKCVPYW 365

Query: 2324 PNILGKTTMVSNRLRLALVRMQQLKGFVVRAMTLEDIQTRE-VRHISHLNFTAWPDHDTP 2382
            P +            +          + +R + +  +   + +R I H  + +WPDH  P
Sbjct: 366  PEV--GMQRAYGPYSVTNCGEHDTTEYKLRTLQVSPLDNGDLIREIWHYQYLSWPDHGVP 423

Query: 2383 SQPDDLLTFISYMRH----IHRSGPIITHCSAGIGRSGTLICIDVVLGLISQ---DLDFD 2435
            S+P  +L+F+  +      +  +GPII HCSAGIGR+GT+I ID+++  IS    D D D
Sbjct: 424  SEPGGVLSFLDQINQRQESLPHAGPIIVHCSAGIGRTGTIIVIDMLMENISTKGLDCDID 483

Query: 2436 ISDLVRCMRLQRHGMVQTEDQYIFCYQVILYVL--TRLQAEEEQKQQPQ 2482
            I   ++ +R QR GMVQTE QY F Y  I   +  T+ + E  Q Q+ Q
Sbjct: 484  IQKTIQMVRAQRSGMVQTEAQYKFIYVAIAQFIETTKKKLEVLQSQKGQ 532


>gi|18104991 protein tyrosine phosphatase, non-receptor type 6 isoform
            2 [Homo sapiens]
          Length = 597

 Score =  182 bits (462), Expect = 4e-45
 Identities = 116/289 (40%), Positives = 160/289 (55%), Gaps = 23/289 (7%)

Query: 2215 KELENLQ--ELKPLDQCLIGQTKENRRKNRYKNILPYDATRVPLGDEGG------YINAS 2266
            +E E+LQ  E+K L Q L GQ  EN+ KNRYKNILP+D +RV L           YINA+
Sbjct: 248  EEFESLQKQEVKNLHQRLEGQRPENKGKNRYKNILPFDHSRVILQGRDSNIPGSDYINAN 307

Query: 2267 FIKIPV-GKEEFV--YIACQGPLPTTVGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYW 2323
            +IK  + G +E    YIA QG L  TV DFWQM W++ S VI M T+EVE  + KC  YW
Sbjct: 308  YIKNQLLGPDENAKTYIASQGCLEATVNDFWQMAWQENSRVIVMTTREVEKGRNKCVPYW 367

Query: 2324 PNILGKTTMVSNRLRLALVRMQQLKGFVVRAMTLEDIQTRE-VRHISHLNFTAWPDHDTP 2382
            P +            +          + +R + +  +   + +R I H  + +WPDH  P
Sbjct: 368  PEV--GMQRAYGPYSVTNCGEHDTTEYKLRTLQVSPLDNGDLIREIWHYQYLSWPDHGVP 425

Query: 2383 SQPDDLLTFISYMRH----IHRSGPIITHCSAGIGRSGTLICIDVVLGLISQ---DLDFD 2435
            S+P  +L+F+  +      +  +GPII HCSAGIGR+GT+I ID+++  IS    D D D
Sbjct: 426  SEPGGVLSFLDQINQRQESLPHAGPIIVHCSAGIGRTGTIIVIDMLMENISTKGLDCDID 485

Query: 2436 ISDLVRCMRLQRHGMVQTEDQYIFCYQVILYVL--TRLQAEEEQKQQPQ 2482
            I   ++ +R QR GMVQTE QY F Y  I   +  T+ + E  Q Q+ Q
Sbjct: 486  IQKTIQMVRAQRSGMVQTEAQYKFIYVAIAQFIETTKKKLEVLQSQKGQ 534


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.130    0.371 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 97,100,901
Number of Sequences: 37866
Number of extensions: 4619866
Number of successful extensions: 15824
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 274
Number of HSP's successfully gapped in prelim test: 192
Number of HSP's that attempted gapping in prelim test: 13031
Number of HSP's gapped (non-prelim): 2159
length of query: 2485
length of database: 18,247,518
effective HSP length: 119
effective length of query: 2366
effective length of database: 13,741,464
effective search space: 32512303824
effective search space used: 32512303824
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 71 (32.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.