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Search of human proteins with 182765464
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|182765464 arachidonate lipoxygenase 3 [Homo sapiens]
(711 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|182765464 arachidonate lipoxygenase 3 [Homo sapiens] 1482 0.0
gi|4502053 arachidonate 12-lipoxygenase, 12R type [Homo sapiens] 808 0.0
gi|85067501 arachidonate 15-lipoxygenase, second type isoform d ... 724 0.0
gi|85067499 arachidonate 15-lipoxygenase, second type isoform a ... 673 0.0
gi|85067503 arachidonate 15-lipoxygenase, second type isoform b ... 586 e-167
gi|4502057 arachidonate 5-lipoxygenase [Homo sapiens] 514 e-145
gi|154426292 arachidonate 12-lipoxygenase [Homo sapiens] 462 e-130
gi|40316937 arachidonate 15-lipoxygenase [Homo sapiens] 434 e-121
gi|239050813 lipoxygenase homology domains 1 isoform 1 [Homo sap... 46 1e-04
gi|224458290 lipoxygenase homology domains 1 isoform 3 [Homo sap... 46 1e-04
gi|224458288 lipoxygenase homology domains 1 isoform 2 [Homo sap... 37 0.063
gi|239754889 PREDICTED: similar to hCG2036697 [Homo sapiens] 37 0.063
gi|239749428 PREDICTED: hypothetical protein XP_002347033 [Homo ... 37 0.063
gi|239743562 PREDICTED: hypothetical protein XP_002342894 [Homo ... 37 0.063
gi|23943858 sorting nexin 8 [Homo sapiens] 30 7.7
gi|197333811 URB2 ribosome biogenesis 2 homolog [Homo sapiens] 30 7.7
>gi|182765464 arachidonate lipoxygenase 3 [Homo sapiens]
Length = 711
Score = 1482 bits (3836), Expect = 0.0
Identities = 711/711 (100%), Positives = 711/711 (100%)
Query: 1 MAVYRLCVTTGPYLRAGTLDNISVTLVGTCGESPKQRLDRMGRDFAPGSVQKYKVRCTAE 60
MAVYRLCVTTGPYLRAGTLDNISVTLVGTCGESPKQRLDRMGRDFAPGSVQKYKVRCTAE
Sbjct: 1 MAVYRLCVTTGPYLRAGTLDNISVTLVGTCGESPKQRLDRMGRDFAPGSVQKYKVRCTAE 60
Query: 61 LGELLLLRVHKERYAFFRKDSWYCSRICVTEPDGSVSHFPCYQWIEGYCTVELRPGTART 120
LGELLLLRVHKERYAFFRKDSWYCSRICVTEPDGSVSHFPCYQWIEGYCTVELRPGTART
Sbjct: 61 LGELLLLRVHKERYAFFRKDSWYCSRICVTEPDGSVSHFPCYQWIEGYCTVELRPGTART 120
Query: 121 ICQDSLPLLLDHRTRELRARQECYRWKIYAPGFPCMVDVNSFQEMESDKKFALTKTTTCV 180
ICQDSLPLLLDHRTRELRARQECYRWKIYAPGFPCMVDVNSFQEMESDKKFALTKTTTCV
Sbjct: 121 ICQDSLPLLLDHRTRELRARQECYRWKIYAPGFPCMVDVNSFQEMESDKKFALTKTTTCV 180
Query: 181 DQGDSSGNRYLPGFPMKIDIPSLMYMEPNVRYSATKTISLLFNAIPASLGMKLRGLLDRK 240
DQGDSSGNRYLPGFPMKIDIPSLMYMEPNVRYSATKTISLLFNAIPASLGMKLRGLLDRK
Sbjct: 181 DQGDSSGNRYLPGFPMKIDIPSLMYMEPNVRYSATKTISLLFNAIPASLGMKLRGLLDRK 240
Query: 241 GSWKKLDDMQNIFWCHKTFTTKYVTEHWCEDHFFGYQYLNGVNPVMLHCISSLPSKLPVT 300
GSWKKLDDMQNIFWCHKTFTTKYVTEHWCEDHFFGYQYLNGVNPVMLHCISSLPSKLPVT
Sbjct: 241 GSWKKLDDMQNIFWCHKTFTTKYVTEHWCEDHFFGYQYLNGVNPVMLHCISSLPSKLPVT 300
Query: 301 NDMVAPLLGQDTCLQTELERGNIFLADYWILAEAPTHCLNGRQQYVAAPLCLLWLSPQGA 360
NDMVAPLLGQDTCLQTELERGNIFLADYWILAEAPTHCLNGRQQYVAAPLCLLWLSPQGA
Sbjct: 301 NDMVAPLLGQDTCLQTELERGNIFLADYWILAEAPTHCLNGRQQYVAAPLCLLWLSPQGA 360
Query: 361 LVPLAIQLSQTPGPDSPIFLPTDSEWDWLLAKTWVRNSEFLVHENNTHFLCTHLLCEAFA 420
LVPLAIQLSQTPGPDSPIFLPTDSEWDWLLAKTWVRNSEFLVHENNTHFLCTHLLCEAFA
Sbjct: 361 LVPLAIQLSQTPGPDSPIFLPTDSEWDWLLAKTWVRNSEFLVHENNTHFLCTHLLCEAFA 420
Query: 421 MATLRQLPLCHPIYKLLLPHTRYTLQVNTIARATLLNPEGLVDQVTSIGRQGLIYLMSTG 480
MATLRQLPLCHPIYKLLLPHTRYTLQVNTIARATLLNPEGLVDQVTSIGRQGLIYLMSTG
Sbjct: 421 MATLRQLPLCHPIYKLLLPHTRYTLQVNTIARATLLNPEGLVDQVTSIGRQGLIYLMSTG 480
Query: 481 LAHFTYTNFCLPDSLRARGVLAIPNYHYRDDGLKIWAAIESFVSEIVGYYYPSDASVQQD 540
LAHFTYTNFCLPDSLRARGVLAIPNYHYRDDGLKIWAAIESFVSEIVGYYYPSDASVQQD
Sbjct: 481 LAHFTYTNFCLPDSLRARGVLAIPNYHYRDDGLKIWAAIESFVSEIVGYYYPSDASVQQD 540
Query: 541 SELQAWTGEIFAQAFLGRESSGFPSRLCTPGEMVKFLTAIIFNCSAQHAAVNSGQHDFGA 600
SELQAWTGEIFAQAFLGRESSGFPSRLCTPGEMVKFLTAIIFNCSAQHAAVNSGQHDFGA
Sbjct: 541 SELQAWTGEIFAQAFLGRESSGFPSRLCTPGEMVKFLTAIIFNCSAQHAAVNSGQHDFGA 600
Query: 601 WMPNAPSSMRQPPPQTKGTTTLKTYLDTLPEVNISCNNLLLFWLVSQEPKDQRPLGTYPD 660
WMPNAPSSMRQPPPQTKGTTTLKTYLDTLPEVNISCNNLLLFWLVSQEPKDQRPLGTYPD
Sbjct: 601 WMPNAPSSMRQPPPQTKGTTTLKTYLDTLPEVNISCNNLLLFWLVSQEPKDQRPLGTYPD 660
Query: 661 EHFTEEAPRRSIAAFQSRLAQISRDIQERNQGLALPYTYLDPPLIENSVSI 711
EHFTEEAPRRSIAAFQSRLAQISRDIQERNQGLALPYTYLDPPLIENSVSI
Sbjct: 661 EHFTEEAPRRSIAAFQSRLAQISRDIQERNQGLALPYTYLDPPLIENSVSI 711
>gi|4502053 arachidonate 12-lipoxygenase, 12R type [Homo sapiens]
Length = 701
Score = 808 bits (2086), Expect = 0.0
Identities = 385/711 (54%), Positives = 508/711 (71%), Gaps = 10/711 (1%)
Query: 1 MAVYRLCVTTGPYLRAGTLDNISVTLVGTCGESPKQRLDRMGRDFAPGSVQKYKVRCTAE 60
MA Y++ V TG L +GT D+IS+T+VGT GES KQ L+ GRDFA G+V +Y V+C +
Sbjct: 1 MATYKVRVATGTDLLSGTRDSISLTIVGTQGESHKQLLNHFGRDFATGAVGQYTVQCPQD 60
Query: 61 LGELLLLRVHKERYAFFRKDSWYCSRICVTEPDGSVSHFPCYQWIEGYCTVELRPGTART 120
LGEL+++R+HKERYAFF KD WYC+ + + P+G + HFP YQW++GY T+ LR T +T
Sbjct: 61 LGELIIIRLHKERYAFFPKDPWYCNYVQICAPNGRIYHFPAYQWMDGYETLALREATGKT 120
Query: 121 ICQDSLPLLLDHRTRELRARQECYRWKIYAPGFPCMVDVNSFQEMESDKKFALTKTTTCV 180
DSLP+LL+HR E+RA+Q+ Y W+++ PG P V + S++ +
Sbjct: 121 TADDSLPVLLEHRKEEIRAKQDFYHWRVFLPGLPSYVHIPSYRPPVRRHR---------- 170
Query: 181 DQGDSSGNRYLPGFPMKIDIPSLMYMEPNVRYSATKTISLLFNAIPASLGMKLRGLLDRK 240
+ N Y+PGFP+ I+ + ++ N+RYS KT S P +L K+RGLLD K
Sbjct: 171 NPNRPEWNGYIPGFPILINFKATKFLNLNLRYSFLKTASFFVRLGPMALAFKVRGLLDCK 230
Query: 241 GSWKKLDDMQNIFWCHKTFTTKYVTEHWCEDHFFGYQYLNGVNPVMLHCISSLPSKLPVT 300
SWK+L D++ IF K+ ++YV EHW ED FFGYQYLNGVNP ++ + +P K PVT
Sbjct: 231 HSWKRLKDIRKIFPGKKSVVSEYVAEHWAEDTFFGYQYLNGVNPGLIRRCTRIPDKFPVT 290
Query: 301 NDMVAPLLGQDTCLQTELERGNIFLADYWILAEAPTHCLNGRQQYVAAPLCLLWLSPQGA 360
+DMVAP LG+ TCLQ ELE+GNI+LADY I+ PT L+GR+Q+ APLCLL P+G
Sbjct: 291 DDMVAPFLGEGTCLQAELEKGNIYLADYRIMEGIPTVELSGRKQHHCAPLCLLHFGPEGK 350
Query: 361 LVPLAIQLSQTPGPDSPIFLPTDSEWDWLLAKTWVRNSEFLVHENNTHFLCTHLLCEAFA 420
++P+AIQLSQTPGPD PIFLP+DSEWDWLLAKTWVR +EF HE H L THL+ EAF
Sbjct: 351 MMPIAIQLSQTPGPDCPIFLPSDSEWDWLLAKTWVRYAEFYSHEAIAHLLETHLIAEAFC 410
Query: 421 MATLRQLPLCHPIYKLLLPHTRYTLQVNTIARATLLNPEGLVDQVTSIGRQGLIYLMSTG 480
+A LR LP+CHP+YKLL+PHTRYT+Q+N+I RA LLN GL + S+G +G +M
Sbjct: 411 LALLRNLPMCHPLYKLLIPHTRYTVQINSIGRAVLLNEGGLSAKGMSLGVEGFAGVMVRA 470
Query: 481 LAHFTYTNFCLPDSLRARGVLAIPNYHYRDDGLKIWAAIESFVSEIVGYYYPSDASVQQD 540
L+ TY + LP+ RGV +P Y+YRDD L +W A+E +V+EI+ YYYPSDA+V+ D
Sbjct: 471 LSELTYDSLYLPNDFVERGVQDLPGYYYRDDSLAVWNALEKYVTEIITYYYPSDAAVEGD 530
Query: 541 SELQAWTGEIFAQAFLGRESSGFPSRLCTPGEMVKFLTAIIFNCSAQHAAVNSGQHDFGA 600
ELQ+W EIF + LGRESSGFP L T E+++++T +I+ CSA+HAAVN+GQ +F A
Sbjct: 531 PELQSWVQEIFKECLLGRESSGFPRCLRTVPELIRYVTIVIYTCSAKHAAVNTGQMEFTA 590
Query: 601 WMPNAPSSMRQPPPQTKGTTTLKTYLDTLPEVNISCNNLLLFWLVSQEPKDQRPLGTYPD 660
WMPN P+SMR PP QTKG TTL+T++DTLP+V +C LL+ W +S+EP D+RPLG +PD
Sbjct: 591 WMPNFPASMRNPPIQTKGLTTLETFMDTLPDVKTTCITLLVLWTLSREPDDRRPLGHFPD 650
Query: 661 EHFTEEAPRRSIAAFQSRLAQISRDIQERNQGLALPYTYLDPPLIENSVSI 711
HF EEAPRRSI AF+ RL QIS DI++RN+ L +PY YLDP LIENS+SI
Sbjct: 651 IHFVEEAPRRSIEAFRQRLNQISHDIRQRNKCLPIPYYYLDPVLIENSISI 701
>gi|85067501 arachidonate 15-lipoxygenase, second type isoform d
[Homo sapiens]
Length = 676
Score = 724 bits (1868), Expect = 0.0
Identities = 369/717 (51%), Positives = 475/717 (66%), Gaps = 47/717 (6%)
Query: 1 MAVYRLCVTTGPYLRAGTLDNISVTLVGTCGESPKQRLDRMGRDFAPGSVQKYKVRCTAE 60
MA +R+ V+TG AGT D +SV++VGT GESP LD +G++F G+ + ++V +
Sbjct: 1 MAEFRVRVSTGEAFGAGTWDKVSVSIVGTRGESPPLPLDNLGKEFTAGAEEDFQVTLPED 60
Query: 61 LGELLLLRVHKERYAF-----FRKDSWYCSRICVTEPDGSVSHFPCYQWIEGYCTVELRP 115
+G +LLLRVHK D+W+C +T P G FPCYQW+EG T+ L+
Sbjct: 61 VGRVLLLRVHKAPPVLPLLGPLAPDAWFCRWFQLTPPRGGHLLFPCYQWLEGAGTLVLQE 120
Query: 116 GTARTICQDSLPLLLDHRTRELRARQECYRWKIYAPGFPCMVDVNSFQEMESDKKFALTK 175
GTA+ D P+L R EL+ARQE Y+WK Y P
Sbjct: 121 GTAKVSWADHHPVLQQQRQEELQARQEMYQWKAYNP------------------------ 156
Query: 176 TTTCVDQGDSSGNRYLPGFPMKIDIPSLMYMEPNVRYSATKTISLLFNAIPASLGMKLRG 235
G+P +D ++ +E N++YS K + A A MK++G
Sbjct: 157 -----------------GWPHCLDEKTVEDLELNIKYSTAKNANFYLQAGSAFAEMKIKG 199
Query: 236 LLDRKGSWKKLDDMQNIFWCHKTFTTKYVTEHWCEDHFFGYQYLNGVNPVMLHCISSLPS 295
LLDRKG W+ L++M+ IF +T ++ EHW ED FF Q+LNG+NPV++ LP
Sbjct: 200 LLDRKGLWRSLNEMKRIFNFRRTPAAEHAFEHWQEDAFFASQFLNGLNPVLIRRCHYLPK 259
Query: 296 KLPVTNDMVAPLLGQDTCLQTELERGNIFLADYWILAEAPTHCLNGRQQYVAAPLCLLWL 355
PVT+ MVA +LG T LQ ELE+G++FL D+ IL+ T+ +NG+ Q+ AAP+ LL+
Sbjct: 260 NFPVTDAMVASVLGPGTSLQAELEKGSLFLVDHGILSGIQTNVINGKPQFSAAPMTLLYQ 319
Query: 356 SPQ-GALVPLAIQLSQTPGPDSPIFLPTDSEWDWLLAKTWVRNSEFLVHENNTHFLCTHL 414
SP G L+PLAIQLSQTPGP+SPIFLPTD +WDWLLAKTWVRN+EF HE TH L +HL
Sbjct: 320 SPGCGPLLPLAIQLSQTPGPNSPIFLPTDDKWDWLLAKTWVRNAEFSFHEALTHLLHSHL 379
Query: 415 LCEAFAMATLRQLPLCHPIYKLLLPHTRYTLQVNTIARATLLNPEGLVDQVTSIGRQGLI 474
L E F +ATLRQLP CHP++KLL+PHTRYTL +NT+AR L+ P +VD+ T IG +G
Sbjct: 380 LPEVFTLATLRQLPHCHPLFKLLIPHTRYTLHINTLARELLIVPGQVVDRSTGIGIEGFS 439
Query: 475 YLMSTGLAHFTYTNFCLPDSLRARGVLAIPNYHYRDDGLKIWAAIESFVSEIVGYYYPSD 534
L+ + Y+ CLP+ +R RGV IP Y+YRDDG++IW A+E FVSEI+G YYPSD
Sbjct: 440 ELIQRNMKQLNYSLLCLPEDIRTRGVEDIPGYYYRDDGMQIWGAVERFVSEIIGIYYPSD 499
Query: 535 ASVQQDSELQAWTGEIFAQAFLGRESSGFPSRLCTPGEMVKFLTAIIFNCSAQHAAVNSG 594
SVQ D ELQAW EIF++ FL +ESSG PS L T +V+++T +IF CSA+HAAV++G
Sbjct: 500 ESVQDDRELQAWVREIFSKGFLNQESSGIPSSLETREALVQYVTMVIFTCSAKHAAVSAG 559
Query: 595 QHDFGAWMPNAPSSMRQPPPQTKGTTTLKTYLDTLPEVNISCNNLLLFWLVSQEPKDQRP 654
Q D AWMPN P SM+ PPP +KG T + ++ TLP VN +C+ +L WL+S+EP DQRP
Sbjct: 560 QFDSCAWMPNLPPSMQLPPPTSKGLATCEGFIATLPPVNATCDVILALWLLSKEPGDQRP 619
Query: 655 LGTYPDEHFTEEAPRRSIAAFQSRLAQISRDIQERNQGLALPYTYLDPPLIENSVSI 711
LGTYPDEHFTEEAPRRSIA FQSRLAQISR IQERNQGL LPYTYLDPPLIENSVSI
Sbjct: 620 LGTYPDEHFTEEAPRRSIATFQSRLAQISRGIQERNQGLVLPYTYLDPPLIENSVSI 676
>gi|85067499 arachidonate 15-lipoxygenase, second type isoform a
[Homo sapiens]
Length = 647
Score = 673 bits (1736), Expect = 0.0
Identities = 352/717 (49%), Positives = 452/717 (63%), Gaps = 76/717 (10%)
Query: 1 MAVYRLCVTTGPYLRAGTLDNISVTLVGTCGESPKQRLDRMGRDFAPGSVQKYKVRCTAE 60
MA +R+ V+TG AGT D +SV++VGT GESP LD +G++F G+ + ++V +
Sbjct: 1 MAEFRVRVSTGEAFGAGTWDKVSVSIVGTRGESPPLPLDNLGKEFTAGAEEDFQVTLPED 60
Query: 61 LGELLLLRVHKERYAF-----FRKDSWYCSRICVTEPDGSVSHFPCYQWIEGYCTVELRP 115
+G +LLLRVHK D+W+C +T P G FPCYQW+EG T+ L+
Sbjct: 61 VGRVLLLRVHKAPPVLPLLGPLAPDAWFCRWFQLTPPRGGHLLFPCYQWLEGAGTLVLQE 120
Query: 116 GTARTICQDSLPLLLDHRTRELRARQECYRWKIYAPGFPCMVDVNSFQEMESDKKFALTK 175
GTA+ D P+L R EL+ARQE Y+WK Y P
Sbjct: 121 GTAKVSWADHHPVLQQQRQEELQARQEMYQWKAYNP------------------------ 156
Query: 176 TTTCVDQGDSSGNRYLPGFPMKIDIPSLMYMEPNVRYSATKTISLLFNAIPASLGMKLRG 235
G+P +D ++ +E N++YS K + A A MK++G
Sbjct: 157 -----------------GWPHCLDEKTVEDLELNIKYSTAKNANFYLQAGSAFAEMKIKG 199
Query: 236 LLDRKGSWKKLDDMQNIFWCHKTFTTKYVTEHWCEDHFFGYQYLNGVNPVMLHCISSLPS 295
LLDRKG W+ L++M+ IF +T ++ EHW ED FF Q+LNG+NPV++ LP
Sbjct: 200 LLDRKGLWRSLNEMKRIFNFRRTPAAEHAFEHWQEDAFFASQFLNGLNPVLIRRCHYLPK 259
Query: 296 KLPVTNDMVAPLLGQDTCLQTELERGNIFLADYWILAEAPTHCLNGRQQYVAAPLCLLWL 355
PVT+ MVA +LG T LQ ELE+G++FL D+ IL+ T+ +NG+ Q+ AAP+ LL+
Sbjct: 260 NFPVTDAMVASVLGPGTSLQAELEKGSLFLVDHGILSGIQTNVINGKPQFSAAPMTLLYQ 319
Query: 356 SPQ-GALVPLAIQLSQTPGPDSPIFLPTDSEWDWLLAKTWVRNSEFLVHENNTHFLCTHL 414
SP G L+PLAIQLSQTPGP+SPIFLPTD +WDWLLAKTWVRN+EF HE TH L +HL
Sbjct: 320 SPGCGPLLPLAIQLSQTPGPNSPIFLPTDDKWDWLLAKTWVRNAEFSFHEALTHLLHSHL 379
Query: 415 LCEAFAMATLRQLPLCHPIYKLLLPHTRYTLQVNTIARATLLNPEGLVDQVTSIGRQGLI 474
L E F +ATLRQLP CHP++K T IG +G
Sbjct: 380 LPEVFTLATLRQLPHCHPLFKS-----------------------------TGIGIEGFS 410
Query: 475 YLMSTGLAHFTYTNFCLPDSLRARGVLAIPNYHYRDDGLKIWAAIESFVSEIVGYYYPSD 534
L+ + Y+ CLP+ +R RGV IP Y+YRDDG++IW A+E FVSEI+G YYPSD
Sbjct: 411 ELIQRNMKQLNYSLLCLPEDIRTRGVEDIPGYYYRDDGMQIWGAVERFVSEIIGIYYPSD 470
Query: 535 ASVQQDSELQAWTGEIFAQAFLGRESSGFPSRLCTPGEMVKFLTAIIFNCSAQHAAVNSG 594
SVQ D ELQAW EIF++ FL +ESSG PS L T +V+++T +IF CSA+HAAV++G
Sbjct: 471 ESVQDDRELQAWVREIFSKGFLNQESSGIPSSLETREALVQYVTMVIFTCSAKHAAVSAG 530
Query: 595 QHDFGAWMPNAPSSMRQPPPQTKGTTTLKTYLDTLPEVNISCNNLLLFWLVSQEPKDQRP 654
Q D AWMPN P SM+ PPP +KG T + ++ TLP VN +C+ +L WL+S+EP DQRP
Sbjct: 531 QFDSCAWMPNLPPSMQLPPPTSKGLATCEGFIATLPPVNATCDVILALWLLSKEPGDQRP 590
Query: 655 LGTYPDEHFTEEAPRRSIAAFQSRLAQISRDIQERNQGLALPYTYLDPPLIENSVSI 711
LGTYPDEHFTEEAPRRSIA FQSRLAQISR IQERNQGL LPYTYLDPPLIENSVSI
Sbjct: 591 LGTYPDEHFTEEAPRRSIATFQSRLAQISRGIQERNQGLVLPYTYLDPPLIENSVSI 647
>gi|85067503 arachidonate 15-lipoxygenase, second type isoform b
[Homo sapiens]
Length = 602
Score = 586 bits (1510), Expect = e-167
Identities = 322/717 (44%), Positives = 416/717 (58%), Gaps = 121/717 (16%)
Query: 1 MAVYRLCVTTGPYLRAGTLDNISVTLVGTCGESPKQRLDRMGRDFAPGSVQKYKVRCTAE 60
MA +R+ V+TG AGT D +SV++VGT GESP LD +G++F G+ + ++V +
Sbjct: 1 MAEFRVRVSTGEAFGAGTWDKVSVSIVGTRGESPPLPLDNLGKEFTAGAEEDFQVTLPED 60
Query: 61 LGELLLLRVHKERYAF-----FRKDSWYCSRICVTEPDGSVSHFPCYQWIEGYCTVELRP 115
+G +LLLRVHK D+W+C +T P G FPCYQW+EG T+ L+
Sbjct: 61 VGRVLLLRVHKAPPVLPLLGPLAPDAWFCRWFQLTPPRGGHLLFPCYQWLEGAGTLVLQE 120
Query: 116 GTARTICQDSLPLLLDHRTRELRARQECYRWKIYAPGFPCMVDVNSFQEMESDKKFALTK 175
GTA+ D P+L R EL+ARQE Y+WK Y P
Sbjct: 121 GTAKVSWADHHPVLQQQRQEELQARQEMYQWKAYNP------------------------ 156
Query: 176 TTTCVDQGDSSGNRYLPGFPMKIDIPSLMYMEPNVRYSATKTISLLFNAIPASLGMKLRG 235
G+P +D ++ +E N++YS K + A A MK++G
Sbjct: 157 -----------------GWPHCLDEKTVEDLELNIKYSTAKNANFYLQAGSAFAEMKIKG 199
Query: 236 LLDRKGSWKKLDDMQNIFWCHKTFTTKYVTEHWCEDHFFGYQYLNGVNPVMLHCISSLPS 295
LLDRKG W+ L++M+ IF +T ++ EHW ED FF Q+LNG+NPV++ LP
Sbjct: 200 LLDRKGLWRSLNEMKRIFNFRRTPAAEHAFEHWQEDAFFASQFLNGLNPVLIRRCHYLPK 259
Query: 296 KLPVTNDMVAPLLGQDTCLQTELERGNIFLADYWILAEAPTHCLNGRQQYVAAPLCLLWL 355
PVT+ MVA +LG T LQ ELE+G++FL D+ IL+ T+ +NG+ Q+ AAP+ LL+
Sbjct: 260 NFPVTDAMVASVLGPGTSLQAELEKGSLFLVDHGILSGIQTNVINGKPQFSAAPMTLLYQ 319
Query: 356 SPQ-GALVPLAIQLSQTPGPDSPIFLPTDSEWDWLLAKTWVRNSEFLVHENNTHFLCTHL 414
SP G L+PLAIQLSQTPGP+SPIFLPTD +WDWLLAKTWVRN+EF HE TH L +HL
Sbjct: 320 SPGCGPLLPLAIQLSQTPGPNSPIFLPTDDKWDWLLAKTWVRNAEFSFHEALTHLLHSHL 379
Query: 415 LCEAFAMATLRQLPLCHPIYKLLLPHTRYTLQVNTIARATLLNPEGLVDQVTSIGRQGLI 474
L E F +ATLRQLP CHP++K T IG +G
Sbjct: 380 LPEVFTLATLRQLPHCHPLFKS-----------------------------TGIGIEGFS 410
Query: 475 YLMSTGLAHFTYTNFCLPDSLRARGVLAIPNYHYRDDGLKIWAAIESFVSEIVGYYYPSD 534
L+ + Y+ CLP+ +R RGV IP Y+YRDDG
Sbjct: 411 ELIQRNMKQLNYSLLCLPEDIRTRGVEDIPGYYYRDDG---------------------- 448
Query: 535 ASVQQDSELQAWTGEIFAQAFLGRESSGFPSRLCTPGEMVKFLTAIIFNCSAQHAAVNSG 594
+Q W G PS L T +V+++T +IF CSA+HAAV++G
Sbjct: 449 --------MQIW---------------GIPSSLETREALVQYVTMVIFTCSAKHAAVSAG 485
Query: 595 QHDFGAWMPNAPSSMRQPPPQTKGTTTLKTYLDTLPEVNISCNNLLLFWLVSQEPKDQRP 654
Q D AWMPN P SM+ PPP +KG T + ++ TLP VN +C+ +L WL+S+EP DQRP
Sbjct: 486 QFDSCAWMPNLPPSMQLPPPTSKGLATCEGFIATLPPVNATCDVILALWLLSKEPGDQRP 545
Query: 655 LGTYPDEHFTEEAPRRSIAAFQSRLAQISRDIQERNQGLALPYTYLDPPLIENSVSI 711
LGTYPDEHFTEEAPRRSIA FQSRLAQISR IQERNQGL LPYTYLDPPLIENSVSI
Sbjct: 546 LGTYPDEHFTEEAPRRSIATFQSRLAQISRGIQERNQGLVLPYTYLDPPLIENSVSI 602
>gi|4502057 arachidonate 5-lipoxygenase [Homo sapiens]
Length = 674
Score = 514 bits (1323), Expect = e-145
Identities = 279/720 (38%), Positives = 405/720 (56%), Gaps = 55/720 (7%)
Query: 1 MAVYRLCVTTGPYLRAGTLDNISVTLVGTCGESPKQRLDR-MGRDFAPGSVQKYKVRCTA 59
M Y + V TG AGT D I ++LVG+ G S K LD+ DF G+V Y V
Sbjct: 1 MPSYTVTVATGSQWFAGTDDYIYLSLVGSAGCSEKHLLDKPFYNDFERGAVDSYDVTVDE 60
Query: 60 ELGELLLLRVHKERYAFFRKDSWYCSRICVTEPDGSVSHFPCYQWIEGYCTVELRPGTAR 119
ELGE+ L+R+ K +Y + D WY I + P G FPCY+WI G V LR G A+
Sbjct: 61 ELGEIQLVRIEKRKY--WLNDDWYLKYITLKTPHGDYIEFPCYRWITGDVEVVLRDGRAK 118
Query: 120 TICQDSLPLLLDHRTRELRARQECYRWKIYAPGFPCMVDVNSFQEMESDKKFALTKTTTC 179
D + +L HR +EL RQ+ YRW
Sbjct: 119 LARDDQIHILKQHRRKELETRQKQYRWM-------------------------------- 146
Query: 180 VDQGDSSGNRYLPGFPMKIDIPSLMYMEPNVRYSATKTISLLFNAIPASLGMKLRGLLDR 239
+ PGFP+ ID + ++++ + K + + N A + + +
Sbjct: 147 ---------EWNPGFPLSIDAKCHKDLPRDIQFDSEKGVDFVLNYSKAMENLFINRFMHM 197
Query: 240 -KGSWKKLDDMQNIFWCHKTFTTKYVTEHWCEDHFFGYQYLNGVNPVMLHCISSLPSKLP 298
+ SW D + IF ++ V HW ED FGYQ+LNG NPV++ + LP KLP
Sbjct: 198 FQSSWNDFADFEKIFVKISNTISERVMNHWQEDLMFGYQFLNGCNPVLIRRCTELPEKLP 257
Query: 299 VTNDMVAPLLGQDTCLQTELERGNIFLADYWIL----AEAPTHCLNGRQQYVAAPLCLLW 354
VT +MV L + L+ E+++GNIF+ D+ +L A C Q++AAP+CLL+
Sbjct: 258 VTTEMVECSLERQLSLEQEVQQGNIFIVDFELLDGIDANKTDPCT---LQFLAAPICLLY 314
Query: 355 LSPQGALVPLAIQLSQTPGPDSPIFLPTDSEWDWLLAKTWVRNSEFLVHENNTHFLCTHL 414
+ +VP+AIQL+Q PG ++PIFLP+D+++DWLLAK WVR+S+F VH+ TH L THL
Sbjct: 315 KNLANKIVPIAIQLNQIPGDENPIFLPSDAKYDWLLAKIWVRSSDFHVHQTITHLLRTHL 374
Query: 415 LCEAFAMATLRQLPLCHPIYKLLLPHTRYTLQVNTIARATLLNPEGLVDQVTSIGRQGLI 474
+ E F +A RQLP HPI+KLL+ H R+T+ +NT AR L+ GL D+ + G G +
Sbjct: 375 VSEVFGIAMYRQLPAVHPIFKLLVAHVRFTIAINTKAREQLICECGLFDKANATGGGGHV 434
Query: 475 YLMSTGLAHFTYTNFCLPDSLRARGVLA---IPNYHYRDDGLKIWAAIESFVSEIVGYYY 531
++ + TY + C P++++ARG+ + IP Y YRDDGL +W AI +F +E+V YY
Sbjct: 435 QMVQRAMKDLTYASLCFPEAIKARGMESKEDIPYYFYRDDGLLVWEAIRTFTAEVVDIYY 494
Query: 532 PSDASVQQDSELQAWTGEIFAQAFLGRESSGFPSRLCTPGEMVKFLTAIIFNCSAQHAAV 591
D V++D ELQ + +++ GR+SSGFP + + ++ ++LT +IF SAQHAAV
Sbjct: 495 EGDQVVEEDPELQDFVNDVYVYGMRGRKSSGFPKSVKSREQLSEYLTVVIFTASAQHAAV 554
Query: 592 NSGQHDFGAWMPNAPSSMRQPPPQTKGTTTLKTYLDTLPEVNISCNNLLLFWLVSQEPKD 651
N GQ+D+ +W+PNAP +MR PPP KG T++ +DTLP+ SC +L W +SQ ++
Sbjct: 555 NFGQYDWCSWIPNAPPTMRAPPPTAKGVVTIEQIVDTLPDRGRSCWHLGAVWALSQFQEN 614
Query: 652 QRPLGTYPDEHFTEEAPRRSIAAFQSRLAQISRDIQERNQGLALPYTYLDPPLIENSVSI 711
+ LG YP+EHF E+ + ++A F+ L I I ERN+ LPY YL P I NSV+I
Sbjct: 615 ELFLGMYPEEHFIEKPVKEAMARFRKNLEAIVSVIAERNKKKQLPYYYLSPDRIPNSVAI 674
>gi|154426292 arachidonate 12-lipoxygenase [Homo sapiens]
Length = 663
Score = 462 bits (1189), Expect = e-130
Identities = 260/715 (36%), Positives = 385/715 (53%), Gaps = 56/715 (7%)
Query: 1 MAVYRLCVTTGPYLRAGTLDNISVTLVGTCGESPKQRLDRMGRDFAPGSVQKYKVRCTAE 60
M YR+ V TG +L +G+ + + + LVGT GE+ + R R G +++ +
Sbjct: 1 MGRYRIRVATGAWLFSGSYNRVQLWLVGTRGEAELELQLRPAR----GEEEEFDHDVAED 56
Query: 61 LGELLLLRVHKERYAFFRKDSWYCSRICVTEPDGSVS-HFPCYQWIEGYCTVELRPGTAR 119
LG L +R+ K + D+W+C RI V P FPCY+W++G + L GTAR
Sbjct: 57 LGLLQFVRLRKHHWLV--DDAWFCDRITVQGPGACAEVAFPCYRWVQGEDILSLPEGTAR 114
Query: 120 TICQDSLPLLLDHRTRELRARQECYRWKIYAPGFPCMVDVNSFQEMESDKKFALTKTTTC 179
++L + HR +EL+ RQ+ Y W + G P T
Sbjct: 115 LPGDNALDMFQKHREKELKDRQQIYCWATWKEGLPL---------------------TIA 153
Query: 180 VDQGDSSGNRYLPGFPMKIDIPSLMYMEPNVRYSATKTISLLFNAIPASLGMKLRGLLDR 239
D+ D D+P PN+R+ K + + +L M L+ +
Sbjct: 154 ADRKD--------------DLP------PNMRFHEEKRLDFEWTLKAGALEMALKRVYTL 193
Query: 240 KGSWKKLDDMQNIFWCHKTFTTKYVTEHWCEDHFFGYQYLNGVNPVMLHCISSLPSKLPV 299
SW L+D IFW K+ + V + W +D F YQ+LNG NP++L +SLPS+L +
Sbjct: 194 LSSWNCLEDFDQIFWGQKSALAEKVRQCWQDDELFSYQFLNGANPMLLRRSTSLPSRLVL 253
Query: 300 TNDMVAPLLGQDTCLQTELERGNIFLADYWILAEAPTHCLNGRQQYVAAPLCLLWLSPQG 359
+ M L Q L+ EL+ G++F AD+ +L P + + G +QY+AAPL +L + P G
Sbjct: 254 PSGM-EELQAQ---LEKELQNGSLFEADFILLDGIPANVIRGEKQYLAAPLVMLKMEPNG 309
Query: 360 ALVPLAIQLSQTPGPDSP---IFLPTDSEWDWLLAKTWVRNSEFLVHENNTHFLCTHLLC 416
L P+ IQ+ Q P P SP +FLP+D WLLAK+WVRNS+F +HE H L THL+
Sbjct: 310 KLQPMVIQI-QPPNPSSPTPTLFLPSDPPLAWLLAKSWVRNSDFQLHEIQYHLLNTHLVA 368
Query: 417 EAFAMATLRQLPLCHPIYKLLLPHTRYTLQVNTIARATLLNPEGLVDQVTSIGRQGLIYL 476
E A+AT+R LP HPI+K L+PH RYT+++NT AR L++ G+ D+ S G G + L
Sbjct: 369 EVIAVATMRCLPGLHPIFKFLIPHIRYTMEINTRARTQLISDGGIFDKAVSTGGGGHVQL 428
Query: 477 MSTGLAHFTYTNFCLPDSLRARGVLAIPNYHYRDDGLKIWAAIESFVSEIVGYYYPSDAS 536
+ A TY + C PD L RG+L +P Y D L++W I +V IV +Y D
Sbjct: 429 LRRAAAQLTYCSLCPPDDLADRGLLGLPGALYAHDALRLWEIIARYVEGIVHLFYQRDDI 488
Query: 537 VQQDSELQAWTGEIFAQAFLGRESSGFPSRLCTPGEMVKFLTAIIFNCSAQHAAVNSGQH 596
V+ D ELQAW EI + GFP + ++ FLT +F C+AQHAA+N GQ
Sbjct: 489 VKGDPELQAWCREITEVGLCQAQDRGFPVSFQSQSQLCHFLTMCVFTCTAQHAAINQGQL 548
Query: 597 DFGAWMPNAPSSMRQPPPQTKGTTTLKTYLDTLPEVNISCNNLLLFWLVSQEPKDQRPLG 656
D+ AW+PNAP +MR PPP TK T+ T + +LP+V +C + + W +S+ D PLG
Sbjct: 549 DWYAWVPNAPCTMRMPPPTTKEDVTMATVMGSLPDVRQACLQMAISWHLSRRQPDMVPLG 608
Query: 657 TYPDEHFTEEAPRRSIAAFQSRLAQISRDIQERNQGLALPYTYLDPPLIENSVSI 711
+ +++F+ P+ + F++ L ++ ++I RN+ L PY YL P IENSV+I
Sbjct: 609 HHKEKYFSGPKPKAVLNQFRTDLEKLEKEITARNEQLDWPYEYLKPSCIENSVTI 663
>gi|40316937 arachidonate 15-lipoxygenase [Homo sapiens]
Length = 662
Score = 434 bits (1115), Expect = e-121
Identities = 255/716 (35%), Positives = 376/716 (52%), Gaps = 59/716 (8%)
Query: 1 MAVYRLCVTTGPYLRAGTLDNISVTLVGTCGESPKQRLDRMGRDFAP--GSVQKYKVRCT 58
M +YR+ V+TG L AG+ + + + LVG GE+ +G+ P G + KV
Sbjct: 1 MGLYRIRVSTGASLYAGSNNQVQLWLVGQHGEAA------LGKRLWPARGKETELKVEVP 54
Query: 59 AELGELLLLRVHKERYAFFRKDSWYCSRICVTEPD-GSVSHFPCYQWIEGYCTVELRPGT 117
LG LL +++ K + D+W+C+ I V P G FPCY+W+EG + L GT
Sbjct: 55 EYLGPLLFVKLRKRH--LLKDDAWFCNWISVQGPGAGDEVRFPCYRWVEGNGVLSLPEGT 112
Query: 118 ARTICQDSLPLLLDHRTRELRARQECYRWKIYAPGFPCMVDVNSFQEMESDKKFALTKTT 177
RT+ +D L HR EL R++ YRW + G + ++ D++F K
Sbjct: 113 GRTVGEDPQGLFQKHREEELEERRKLYRWGNWKDGLILNMAGAKLYDLPVDERFLEDK-- 170
Query: 178 TCVDQGDSSGNRYLPGFPMKIDIPSLMYMEPNVRYSATKTISLLFNAIPASLGMKLRGLL 237
V + + L AI SL +
Sbjct: 171 -------------------------------RVDFEVSLAKGLADLAIKDSLNVLT---- 195
Query: 238 DRKGSWKKLDDMQNIFWCHKTFTTKYVTEHWCEDHFFGYQYLNGVNPVMLHCISSLPSKL 297
WK LDD IFWC ++ + V + W ED FGYQ+LNG NPV+L + LP++L
Sbjct: 196 ----CWKDLDDFNRIFWCGQSKLAERVRDSWKEDALFGYQFLNGANPVVLRRSAHLPARL 251
Query: 298 PVTNDMVAPLLGQDTCLQTELERGNIFLADYWILAEAPTHCLNGRQQYVAAPLCLLWLSP 357
M L Q L+ ELE G +F AD+ +L + + QQ++AAPL +L L P
Sbjct: 252 VFPPGM-EELQAQ---LEKELEGGTLFEADFSLLDGIKANVILCSQQHLAAPLVMLKLQP 307
Query: 358 QGALVPLAIQLS--QTPGPDSPIFLPTDSEWDWLLAKTWVRNSEFLVHENNTHFLCTHLL 415
G L+P+ IQL +T P P+FLPTD WLLAK WVR+S+F +HE +H L HL+
Sbjct: 308 DGKLLPMVIQLQLPRTGSPPPPLFLPTDPPMAWLLAKCWVRSSDFQLHELQSHLLRGHLM 367
Query: 416 CEAFAMATLRQLPLCHPIYKLLLPHTRYTLQVNTIARATLLNPEGLVDQVTSIGRQGLIY 475
E +AT+R LP HPI+KL++PH RYTL++N AR L++ G+ DQ+ S G G +
Sbjct: 368 AEVIVVATMRCLPSIHPIFKLIIPHLRYTLEINVRARTGLVSDMGIFDQIMSTGGGGHVQ 427
Query: 476 LMSTGLAHFTYTNFCLPDSLRARGVLAIPNYHYRDDGLKIWAAIESFVSEIVGYYYPSDA 535
L+ A TY++FC PD L RG+L + + Y D L++W I +V IV +Y +D
Sbjct: 428 LLKQAGAFLTYSSFCPPDDLADRGLLGVKSSFYAQDALRLWEIIYRYVEGIVSLHYKTDV 487
Query: 536 SVQQDSELQAWTGEIFAQAFLGRESSGFPSRLCTPGEMVKFLTAIIFNCSAQHAAVNSGQ 595
+V+ D ELQ W EI G + GFP L ++ F+T IF C+ QHA+V+ GQ
Sbjct: 488 AVKDDPELQTWCREITEIGLQGAQDRGFPVSLQARDQVCHFVTMCIFTCTGQHASVHLGQ 547
Query: 596 HDFGAWMPNAPSSMRQPPPQTKGTTTLKTYLDTLPEVNISCNNLLLFWLVSQEPKDQRPL 655
D+ +W+PNAP +MR PPP TK TL+T + TLP + + + + W + + +
Sbjct: 548 LDWYSWVPNAPCTMRLPPPTTK-DATLETVMATLPNFHQASLQMSITWQLGRRQPVMVAV 606
Query: 656 GTYPDEHFTEEAPRRSIAAFQSRLAQISRDIQERNQGLALPYTYLDPPLIENSVSI 711
G + +E+F+ P+ + F+ LA + ++I+ RN L +PY YL P ++ENSV+I
Sbjct: 607 GQHEEEYFSGPEPKAVLKKFREELAALDKEIEIRNAKLDMPYEYLRPSVVENSVAI 662
>gi|239050813 lipoxygenase homology domains 1 isoform 1 [Homo sapiens]
Length = 2211
Score = 46.2 bits (108), Expect = 1e-04
Identities = 33/105 (31%), Positives = 54/105 (51%), Gaps = 5/105 (4%)
Query: 4 YRLCVTTGPYLRAGTLDNISVTLVGTCGESPKQRLDRMGRD-FAPGSVQKYKVRCTAELG 62
Y + VTTG AGT N+ VT+ G G++ K+ L + R+ F GS ++ + T ELG
Sbjct: 2094 YEVIVTTGYEPGAGTDANVFVTIFGANGDTGKRELKQKMRNLFERGSTDRFFLE-TLELG 2152
Query: 63 ELLLLRVHKERYAFFRKDSWYCSRICVTEPD-GSVSHFPCYQWIE 106
EL +R+ + + W ++ VT G + F C +W++
Sbjct: 2153 ELRKVRLEHDSSGYC--SGWLVEKVEVTNTSTGVATIFNCGRWLD 2195
Score = 45.8 bits (107), Expect = 1e-04
Identities = 32/122 (26%), Positives = 59/122 (48%), Gaps = 14/122 (11%)
Query: 4 YRLCVTTGPYLRAGTLDNISVTL----VGTCGESPKQRLDRMGRDFAPGSVQKYKVRCTA 59
Y + V TG +AGT N+ +T+ G GE P ++ D+ + F G + +
Sbjct: 1024 YEVQVVTGNVPKAGTDANVYLTIYGEEYGDTGERPLKKSDKSNK-FEQGQTDTFTI-YAI 1081
Query: 60 ELGELLLLRVHKERYAFFRKDSWYCSRICVTEPDGSVS-HFPCYQWI-----EGYCTVEL 113
+LG L +R+ + + W+ RI +T+ + ++ +FPC +W+ +G + EL
Sbjct: 1082 DLGALTKIRIRHDNTG--NRAGWFLDRIDITDMNNEITYYFPCQRWLAVEEDDGQLSREL 1139
Query: 114 RP 115
P
Sbjct: 1140 LP 1141
Score = 44.7 bits (104), Expect = 3e-04
Identities = 32/106 (30%), Positives = 49/106 (46%), Gaps = 6/106 (5%)
Query: 3 VYRLCVTTGPYLRAGTLDNISVTLVGTCGESPKQRLDRMGRD-FAPGSVQKYKVRCTAEL 61
VY + TG AGT N+ +TL G G SPK +L + F G+V ++VR T +
Sbjct: 44 VYEVVTATGDVRGAGTDANVFITLFGENGLSPKLQLTSKSKSAFEKGNVDVFRVR-TNNV 102
Query: 62 GELLLLRVHKERYAFFRKDSWYCSRICVTEPDGS--VSHFPCYQWI 105
G + +R+ + SWY + VT+ +F C W+
Sbjct: 103 GLIYKVRIEHDNTGL--NASWYLDHVIVTDMKRPHLRYYFNCNNWL 146
Score = 38.9 bits (89), Expect = 0.017
Identities = 30/115 (26%), Positives = 50/115 (43%), Gaps = 15/115 (13%)
Query: 1 MAVYRLCVTTGPYLRAGTLDNISVTLVGTCGESPKQRLDRMGRD---FAPGSVQKYKVRC 57
MA Y + V TG AGT N+ + L G G++ ++ L + F G+ ++ +
Sbjct: 552 MARYHVTVCTGELEGAGTDANVYLCLFGDVGDTGERLLYNCRNNTDLFEKGNADEFTIE- 610
Query: 58 TAELGELLLLRVHKERYAFFRKDS---WYCSRICVTE---PDGSVSHFPCYQWIE 106
+ + V + R K S WY R+ V E P+ FPC +W++
Sbjct: 611 -----SVTMRNVRRVRIRHDGKGSGSGWYLDRVLVREEGQPESDNVEFPCLRWLD 660
Score = 37.0 bits (84), Expect = 0.063
Identities = 30/110 (27%), Positives = 50/110 (45%), Gaps = 15/110 (13%)
Query: 4 YRLCVTTGPYLRAGTLDNISVTLVGTCGE-------SPKQRLDRMGRDFAPGSVQKYKVR 56
+ + + TG AGT N+ +TL GT + S K D+ RD S++ + V
Sbjct: 1177 FSVTIKTGVKKNAGTDANVFITLFGTQDDTGMTLLKSSKTNSDKFERD----SIEIFTVE 1232
Query: 57 CTAELGELLLLRVHKERYAFFRKDSWYCSRICVTEPD-GSVSHFPCYQWI 105
T +LG+L +R+ + + W+ + V P G FPC +W+
Sbjct: 1233 -TLDLGDLWKVRLGHDNTG--KAPGWFVDWVEVDAPSLGKCMTFPCGRWL 1279
Score = 36.6 bits (83), Expect = 0.083
Identities = 24/104 (23%), Positives = 52/104 (50%), Gaps = 6/104 (5%)
Query: 4 YRLCVTTGPYLRAGTLDNISVTLVGTCGESPKQRLDRMGRDFAPGSVQKYKVRCTAELGE 63
Y + V TG + AGT ++ + + G G++ ++RL+ +F G+ ++ + +LG+
Sbjct: 174 YEVKVYTGDVIGAGTDADVFINIFGEYGDTGERRLENEKDNFEKGAEDRF-ILDAPDLGQ 232
Query: 64 LLLLRV-HKERYAFFRKDSWYCSRICVTEPDGSVSH-FPCYQWI 105
L+ + V H + W+ S+I + + + FP +W+
Sbjct: 233 LMKINVGHNNKGG---SAGWFLSQIVIEDIGNKRKYDFPLNRWL 273
Score = 33.5 bits (75), Expect = 0.70
Identities = 23/104 (22%), Positives = 49/104 (47%), Gaps = 4/104 (3%)
Query: 4 YRLCVTTGPYLRAGTLDNISVTLVGTCGESPKQRLDRMGRDFAPGSVQKYKVRCTAELGE 63
+ L V T +AGT I + + G G + + L+ + F PG ++K+++ +LG
Sbjct: 427 WSLWVWTTDLKKAGTNSPIFIQIYGQKGRTDEILLNPNNKWFKPGIIEKFRIE-LPDLGR 485
Query: 64 LLLLRVHKERYAFFRKDSWYCSRICVTEP-DGSVSHFPCYQWIE 106
+RV ++ + W+ R+ + + +F C +W++
Sbjct: 486 FYKIRVWHDKRS--SGSGWHLERMTLMNTLNKDKYNFNCNRWLD 527
Score = 32.7 bits (73), Expect = 1.2
Identities = 27/105 (25%), Positives = 40/105 (38%), Gaps = 5/105 (4%)
Query: 4 YRLCVTTGPYLRAGTLDNISVTLVGTCGESPKQRLDRMG--RDFAPGSVQKYKVRCTAEL 61
Y + V T L AGT N+ + + G G+S L + F + + L
Sbjct: 1825 YTVAVKTSDILGAGTDANVFIIIFGENGDSGTLALKQSANWNKFERNNTDTFNFPDMLSL 1884
Query: 62 GELLLLRVHKERYAFFRKDSWYCSRICVTEPD-GSVSHFPCYQWI 105
G L LRV + F W+ S + V + HF C W+
Sbjct: 1885 GHLCKLRVWHDNKGIF--PGWHLSYVDVKDNSRDETFHFQCDCWL 1927
>gi|224458290 lipoxygenase homology domains 1 isoform 3 [Homo
sapiens]
Length = 512
Score = 46.2 bits (108), Expect = 1e-04
Identities = 33/105 (31%), Positives = 54/105 (51%), Gaps = 5/105 (4%)
Query: 4 YRLCVTTGPYLRAGTLDNISVTLVGTCGESPKQRLDRMGRD-FAPGSVQKYKVRCTAELG 62
Y + VTTG AGT N+ VT+ G G++ K+ L + R+ F GS ++ + T ELG
Sbjct: 395 YEVIVTTGYEPGAGTDANVFVTIFGANGDTGKRELKQKMRNLFERGSTDRFFLE-TLELG 453
Query: 63 ELLLLRVHKERYAFFRKDSWYCSRICVTEPD-GSVSHFPCYQWIE 106
EL +R+ + + W ++ VT G + F C +W++
Sbjct: 454 ELRKVRLEHDSSGYC--SGWLVEKVEVTNTSTGVATIFNCGRWLD 496
Score = 32.7 bits (73), Expect = 1.2
Identities = 27/105 (25%), Positives = 40/105 (38%), Gaps = 5/105 (4%)
Query: 4 YRLCVTTGPYLRAGTLDNISVTLVGTCGESPKQRLDRMG--RDFAPGSVQKYKVRCTAEL 61
Y + V T L AGT N+ + + G G+S L + F + + L
Sbjct: 126 YTVAVKTSDILGAGTDANVFIIIFGENGDSGTLALKQSANWNKFERNNTDTFNFPDMLSL 185
Query: 62 GELLLLRVHKERYAFFRKDSWYCSRICVTEPD-GSVSHFPCYQWI 105
G L LRV + F W+ S + V + HF C W+
Sbjct: 186 GHLCKLRVWHDNKGIF--PGWHLSYVDVKDNSRDETFHFQCDCWL 228
>gi|224458288 lipoxygenase homology domains 1 isoform 2 [Homo
sapiens]
Length = 1114
Score = 37.0 bits (84), Expect = 0.063
Identities = 30/110 (27%), Positives = 50/110 (45%), Gaps = 15/110 (13%)
Query: 4 YRLCVTTGPYLRAGTLDNISVTLVGTCGE-------SPKQRLDRMGRDFAPGSVQKYKVR 56
+ + + TG AGT N+ +TL GT + S K D+ RD S++ + V
Sbjct: 66 FSVTIKTGVKKNAGTDANVFITLFGTQDDTGMTLLKSSKTNSDKFERD----SIEIFTVE 121
Query: 57 CTAELGELLLLRVHKERYAFFRKDSWYCSRICVTEPD-GSVSHFPCYQWI 105
T +LG+L +R+ + + W+ + V P G FPC +W+
Sbjct: 122 -TLDLGDLWKVRLGHDNTG--KAPGWFVDWVEVDAPSLGKCMTFPCGRWL 168
Score = 32.7 bits (73), Expect = 1.2
Identities = 27/105 (25%), Positives = 40/105 (38%), Gaps = 5/105 (4%)
Query: 4 YRLCVTTGPYLRAGTLDNISVTLVGTCGESPKQRLDRMG--RDFAPGSVQKYKVRCTAEL 61
Y + V T L AGT N+ + + G G+S L + F + + L
Sbjct: 776 YTVAVKTSDILGAGTDANVFIIIFGENGDSGTLALKQSANWNKFERNNTDTFNFPDMLSL 835
Query: 62 GELLLLRVHKERYAFFRKDSWYCSRICVTEPD-GSVSHFPCYQWI 105
G L LRV + F W+ S + V + HF C W+
Sbjct: 836 GHLCKLRVWHDNKGIF--PGWHLSYVDVKDNSRDETFHFQCDCWL 878
Score = 32.0 bits (71), Expect = 2.0
Identities = 19/51 (37%), Positives = 29/51 (56%), Gaps = 1/51 (1%)
Query: 4 YRLCVTTGPYLRAGTLDNISVTLVGTCGESPKQRLDRMGRD-FAPGSVQKY 53
Y + VTTG AGT N+ VT+ G G++ K+ L + R+ F GS ++
Sbjct: 1045 YEVIVTTGYEPGAGTDANVFVTIFGANGDTGKRELKQKMRNLFERGSTDRF 1095
>gi|239754889 PREDICTED: similar to hCG2036697 [Homo sapiens]
Length = 1029
Score = 37.0 bits (84), Expect = 0.063
Identities = 31/101 (30%), Positives = 48/101 (47%), Gaps = 6/101 (5%)
Query: 4 YRLCVTTGPYLRAGTLDNISVTLVGTCGESPKQRL--DRMGRDFAPGSVQKYKVRCTAEL 61
Y++ V TG A T + + L G G+S ++L M F G + K++V + L
Sbjct: 636 YQVDVYTGQLKHAETESEVFLCLFGERGDSGLRQLYKSNMQVKFQRGQIDKFQVAAVS-L 694
Query: 62 GELLLLRVHKERYAFFRKDSWYCSRICVTEP-DGSVSHFPC 101
G+L + + E A + WYC ++ V EP S S F C
Sbjct: 695 GKLQKVLLRCE--ASDKSQYWYCEQVIVREPGTTSESIFTC 733
Score = 34.3 bits (77), Expect = 0.41
Identities = 21/109 (19%), Positives = 52/109 (47%), Gaps = 6/109 (5%)
Query: 1 MAVYRLCVTTGPYLRAGTLDNISVTLVGTCGESPKQRL--DRMGRDFAPGSVQKYKVRCT 58
+ +Y + V TG AGT+ N+ +++ G G++ ++L + +F G + +
Sbjct: 40 VTIYEVNVATGELWNAGTVANVYISIHGEKGDTGSRQLFRSKSSFNFLRGQTDTFFLE-A 98
Query: 59 AELGELLLLRVHKERYAFFRKDSWYCSRICVTEPDGSVSH-FPCYQWIE 106
LG+L + + + + W+ + + +P + + F C++W++
Sbjct: 99 VHLGDLCKIVIGHD--GLGPGNGWFLDDVVIKDPTTNYEYAFFCHRWLD 145
>gi|239749428 PREDICTED: hypothetical protein XP_002347033 [Homo
sapiens]
Length = 1029
Score = 37.0 bits (84), Expect = 0.063
Identities = 31/101 (30%), Positives = 48/101 (47%), Gaps = 6/101 (5%)
Query: 4 YRLCVTTGPYLRAGTLDNISVTLVGTCGESPKQRL--DRMGRDFAPGSVQKYKVRCTAEL 61
Y++ V TG A T + + L G G+S ++L M F G + K++V + L
Sbjct: 636 YQVDVYTGQLKHAETESEVFLCLFGERGDSGLRQLYKSNMQVKFQRGQIDKFQVAAVS-L 694
Query: 62 GELLLLRVHKERYAFFRKDSWYCSRICVTEP-DGSVSHFPC 101
G+L + + E A + WYC ++ V EP S S F C
Sbjct: 695 GKLQKVLLRCE--ASDKSQYWYCEQVIVREPGTTSESIFTC 733
Score = 34.3 bits (77), Expect = 0.41
Identities = 21/109 (19%), Positives = 52/109 (47%), Gaps = 6/109 (5%)
Query: 1 MAVYRLCVTTGPYLRAGTLDNISVTLVGTCGESPKQRL--DRMGRDFAPGSVQKYKVRCT 58
+ +Y + V TG AGT+ N+ +++ G G++ ++L + +F G + +
Sbjct: 40 VTIYEVNVATGELWNAGTVANVYISIHGEKGDTGSRQLFRSKSSFNFLRGQTDTFFLE-A 98
Query: 59 AELGELLLLRVHKERYAFFRKDSWYCSRICVTEPDGSVSH-FPCYQWIE 106
LG+L + + + + W+ + + +P + + F C++W++
Sbjct: 99 VHLGDLCKIVIGHD--GLGPGNGWFLDDVVIKDPTTNYEYAFFCHRWLD 145
>gi|239743562 PREDICTED: hypothetical protein XP_002342894 [Homo
sapiens]
Length = 1029
Score = 37.0 bits (84), Expect = 0.063
Identities = 31/101 (30%), Positives = 48/101 (47%), Gaps = 6/101 (5%)
Query: 4 YRLCVTTGPYLRAGTLDNISVTLVGTCGESPKQRL--DRMGRDFAPGSVQKYKVRCTAEL 61
Y++ V TG A T + + L G G+S ++L M F G + K++V + L
Sbjct: 636 YQVDVYTGQLKHAETESEVFLCLFGERGDSGLRQLYKSNMQVKFQRGQIDKFQVAAVS-L 694
Query: 62 GELLLLRVHKERYAFFRKDSWYCSRICVTEP-DGSVSHFPC 101
G+L + + E A + WYC ++ V EP S S F C
Sbjct: 695 GKLQKVLLRCE--ASDKSQYWYCEQVIVREPGTTSESIFTC 733
Score = 34.3 bits (77), Expect = 0.41
Identities = 21/109 (19%), Positives = 52/109 (47%), Gaps = 6/109 (5%)
Query: 1 MAVYRLCVTTGPYLRAGTLDNISVTLVGTCGESPKQRL--DRMGRDFAPGSVQKYKVRCT 58
+ +Y + V TG AGT+ N+ +++ G G++ ++L + +F G + +
Sbjct: 40 VTIYEVNVATGELWNAGTVANVYISIHGEKGDTGSRQLFRSKSSFNFLRGQTDTFFLE-A 98
Query: 59 AELGELLLLRVHKERYAFFRKDSWYCSRICVTEPDGSVSH-FPCYQWIE 106
LG+L + + + + W+ + + +P + + F C++W++
Sbjct: 99 VHLGDLCKIVIGHD--GLGPGNGWFLDDVVIKDPTTNYEYAFFCHRWLD 145
>gi|23943858 sorting nexin 8 [Homo sapiens]
Length = 465
Score = 30.0 bits (66), Expect = 7.7
Identities = 19/50 (38%), Positives = 22/50 (44%)
Query: 91 EPDGSVSHFPCYQWIEGYCTVELRPGTARTICQDSLPLLLDHRTRELRAR 140
E D S P Q IE V+ P +R PLLL H +EL AR
Sbjct: 25 EADPPASDLPTPQAIEPQAIVQQVPAPSRMQMPQGNPLLLSHTLQELLAR 74
>gi|197333811 URB2 ribosome biogenesis 2 homolog [Homo sapiens]
Length = 1524
Score = 30.0 bits (66), Expect = 7.7
Identities = 26/101 (25%), Positives = 47/101 (46%), Gaps = 10/101 (9%)
Query: 337 HCL--NGRQQYVAAPL-------CLLWLSPQGALVPLAIQLSQTPGPDSPIFLPTDSEWD 387
HC+ N R + PL C++ + + PL L TPGP+ ++L S+
Sbjct: 547 HCIMFNMRSLDSSTPLPIVRRTQCMMERMMRELVQPLLALLPDTPGPEPELWLQKVSDSV 606
Query: 388 WLLAKTWVR-NSEFLVHENNTHFLCTHLLCEAFAMATLRQL 427
LL+ TW + ++ F ++ + H + L+ A ++ L L
Sbjct: 607 LLLSYTWAQVDAMFSLNCSQYHSMSGPLIGVALEISNLPSL 647
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.137 0.438
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,946,340
Number of Sequences: 37866
Number of extensions: 1424039
Number of successful extensions: 2981
Number of sequences better than 10.0: 16
Number of HSP's better than 10.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 2919
Number of HSP's gapped (non-prelim): 40
length of query: 711
length of database: 18,247,518
effective HSP length: 109
effective length of query: 602
effective length of database: 14,120,124
effective search space: 8500314648
effective search space used: 8500314648
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.