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Search of human proteins with 18087819
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|18087819 hypothetical protein LOC91283 [Homo sapiens]
(275 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|18087819 hypothetical protein LOC91283 [Homo sapiens] 558 e-159
gi|187607364 tuftelin 1 isoform 2 [Homo sapiens] 37 0.024
gi|9910596 tuftelin 1 isoform 1 [Homo sapiens] 37 0.024
gi|116174778 centrosome spindle pole associated protein 1 isofor... 36 0.032
gi|116174789 centrosome spindle pole associated protein 1 isofor... 36 0.032
gi|164519084 RAB GTPase activating protein 1 [Homo sapiens] 35 0.054
gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap... 35 0.071
gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sap... 35 0.071
gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sap... 35 0.071
gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapi... 35 0.071
gi|60460889 Myb protein P42POP [Homo sapiens] 35 0.071
gi|219555716 synaptonemal complex central element protein 1 isof... 34 0.12
gi|18640754 synaptonemal complex central element protein 1 isofo... 34 0.12
gi|41281571 synovial sarcoma, X breakpoint 2 interacting protein... 34 0.16
gi|219555718 synaptonemal complex central element protein 1 isof... 33 0.21
gi|56550047 uveal autoantigen with coiled-coil domains and ankyr... 33 0.27
gi|59850762 uveal autoantigen with coiled-coil domains and ankyr... 33 0.27
gi|37537558 nuclear apoptosis inducing factor 1 [Homo sapiens] 33 0.27
gi|4759082 serum deprivation response protein [Homo sapiens] 32 0.46
gi|223671870 inhibitor of kappa light polypeptide gene enhancer ... 32 0.60
gi|4504631 inhibitor of kappa light polypeptide gene enhancer in... 32 0.60
gi|153792133 inhibitor of kappa light polypeptide gene enhancer ... 32 0.60
gi|56676397 ankyrin repeat domain 11 [Homo sapiens] 32 0.60
gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo... 32 0.60
gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens] 32 0.79
gi|82697315 RUN and FYVE domain containing 3 isoform 1 [Homo sap... 31 1.0
gi|148839294 Ca2+-dependent activator protein for secretion 2 is... 31 1.0
gi|115495445 ankyrin repeat domain 30A [Homo sapiens] 31 1.3
gi|14042947 testis-specific serine kinase 1 [Homo sapiens] 31 1.3
gi|115648142 centrosomal protein 164kDa [Homo sapiens] 31 1.3
>gi|18087819 hypothetical protein LOC91283 [Homo sapiens]
Length = 275
Score = 558 bits (1438), Expect = e-159
Identities = 275/275 (100%), Positives = 275/275 (100%)
Query: 1 MQNNEIIKPAKYFSELEKSILLALVEKYKYVLECKKSDARTIALKQRTWQALAHEYNSQP 60
MQNNEIIKPAKYFSELEKSILLALVEKYKYVLECKKSDARTIALKQRTWQALAHEYNSQP
Sbjct: 1 MQNNEIIKPAKYFSELEKSILLALVEKYKYVLECKKSDARTIALKQRTWQALAHEYNSQP 60
Query: 61 SVSLRDFKQLKKCWENIKARTKKIMAHERREKVKRSVSPLLSTHVLGKEKIASMLPEQLY 120
SVSLRDFKQLKKCWENIKARTKKIMAHERREKVKRSVSPLLSTHVLGKEKIASMLPEQLY
Sbjct: 61 SVSLRDFKQLKKCWENIKARTKKIMAHERREKVKRSVSPLLSTHVLGKEKIASMLPEQLY 120
Query: 121 FLQSPPEEEPEYHPDASAQESFAVSNRELCDDEKEFIHFPVCEGTSQPEPSCSAVRITAN 180
FLQSPPEEEPEYHPDASAQESFAVSNRELCDDEKEFIHFPVCEGTSQPEPSCSAVRITAN
Sbjct: 121 FLQSPPEEEPEYHPDASAQESFAVSNRELCDDEKEFIHFPVCEGTSQPEPSCSAVRITAN 180
Query: 181 KNYRSKTSQEGALKKMHEEEHHQQMSILQLQLIQMNEVHVAKIQQIERECEMAEEEHRIK 240
KNYRSKTSQEGALKKMHEEEHHQQMSILQLQLIQMNEVHVAKIQQIERECEMAEEEHRIK
Sbjct: 181 KNYRSKTSQEGALKKMHEEEHHQQMSILQLQLIQMNEVHVAKIQQIERECEMAEEEHRIK 240
Query: 241 MEVLNKKKMYWERKLQTFTKEWPVSSFNRPFPNSP 275
MEVLNKKKMYWERKLQTFTKEWPVSSFNRPFPNSP
Sbjct: 241 MEVLNKKKMYWERKLQTFTKEWPVSSFNRPFPNSP 275
>gi|187607364 tuftelin 1 isoform 2 [Homo sapiens]
Length = 365
Score = 36.6 bits (83), Expect = 0.024
Identities = 46/200 (23%), Positives = 83/200 (41%), Gaps = 21/200 (10%)
Query: 42 IALKQRTWQALAHEYN-SQPSVSLRDFKQLKKCWENIKARTKKIMAHERREKVKRSVSPL 100
+ LK R+ + HE N +Q ++ ++ + C + ++ + + + R +
Sbjct: 55 VYLKGRSGDKMIHEKNINQLKSEVQYIQEARNCLQKLREDISSKLDRNLGDSLHRQEIQV 114
Query: 101 LSTHVLGKEKIASMLPEQLYFLQSPPEEEPEYHPDASAQESFAVSNRELCDDEKEFIHFP 160
VL K S P LY SPPE + + D S R+ D +
Sbjct: 115 ----VLEKPNGFSQSPTALY--SSPPEVDTCINEDVE-------SLRKTVQD----LLAK 157
Query: 161 VCEGTSQPEPSCSAVRITANKNYRSKTSQEGALKKMHE--EEHHQQMSILQLQLIQMNEV 218
+ E Q + C A +T ++ R AL++ + E+ ++ LQ +L+ M
Sbjct: 158 LQEAKRQHQSDCVAFEVTLSRYQREAEQSNVALQREEDRVEQKEAEVGELQRRLLGMETE 217
Query: 219 HVAKIQQIERECEMAEEEHR 238
H A + ++ RE E+A EE R
Sbjct: 218 HQALLAKV-REGEVALEELR 236
>gi|9910596 tuftelin 1 isoform 1 [Homo sapiens]
Length = 390
Score = 36.6 bits (83), Expect = 0.024
Identities = 46/200 (23%), Positives = 83/200 (41%), Gaps = 21/200 (10%)
Query: 42 IALKQRTWQALAHEYN-SQPSVSLRDFKQLKKCWENIKARTKKIMAHERREKVKRSVSPL 100
+ LK R+ + HE N +Q ++ ++ + C + ++ + + + R +
Sbjct: 80 VYLKGRSGDKMIHEKNINQLKSEVQYIQEARNCLQKLREDISSKLDRNLGDSLHRQEIQV 139
Query: 101 LSTHVLGKEKIASMLPEQLYFLQSPPEEEPEYHPDASAQESFAVSNRELCDDEKEFIHFP 160
VL K S P LY SPPE + + D S R+ D +
Sbjct: 140 ----VLEKPNGFSQSPTALY--SSPPEVDTCINEDVE-------SLRKTVQD----LLAK 182
Query: 161 VCEGTSQPEPSCSAVRITANKNYRSKTSQEGALKKMHE--EEHHQQMSILQLQLIQMNEV 218
+ E Q + C A +T ++ R AL++ + E+ ++ LQ +L+ M
Sbjct: 183 LQEAKRQHQSDCVAFEVTLSRYQREAEQSNVALQREEDRVEQKEAEVGELQRRLLGMETE 242
Query: 219 HVAKIQQIERECEMAEEEHR 238
H A + ++ RE E+A EE R
Sbjct: 243 HQALLAKV-REGEVALEELR 261
>gi|116174778 centrosome spindle pole associated protein 1 isoform b
[Homo sapiens]
Length = 1221
Score = 36.2 bits (82), Expect = 0.032
Identities = 22/91 (24%), Positives = 44/91 (48%), Gaps = 1/91 (1%)
Query: 154 KEFIHFPVCEGTSQPEPSCSAVRITANKNYRSKTSQEGALKKMHEEEHHQQMSILQLQLI 213
K F+ F + E + E +RI K R Q +++ +EEE ++ + Q +
Sbjct: 736 KNFLRFQIEEKKQREEAERERLRIAEEKEERRLAEQRARIQQEYEEEQEKKREKEEEQRL 795
Query: 214 QMNE-VHVAKIQQIERECEMAEEEHRIKMEV 243
+ E + +A+ +Q E E + EEE + +++
Sbjct: 796 KNEEHIRLAEERQKEAERKKKEEEEKYNLQL 826
>gi|116174789 centrosome spindle pole associated protein 1 isoform a
[Homo sapiens]
Length = 1256
Score = 36.2 bits (82), Expect = 0.032
Identities = 22/91 (24%), Positives = 44/91 (48%), Gaps = 1/91 (1%)
Query: 154 KEFIHFPVCEGTSQPEPSCSAVRITANKNYRSKTSQEGALKKMHEEEHHQQMSILQLQLI 213
K F+ F + E + E +RI K R Q +++ +EEE ++ + Q +
Sbjct: 771 KNFLRFQIEEKKQREEAERERLRIAEEKEERRLAEQRARIQQEYEEEQEKKREKEEEQRL 830
Query: 214 QMNE-VHVAKIQQIERECEMAEEEHRIKMEV 243
+ E + +A+ +Q E E + EEE + +++
Sbjct: 831 KNEEHIRLAEERQKEAERKKKEEEEKYNLQL 861
>gi|164519084 RAB GTPase activating protein 1 [Homo sapiens]
Length = 1069
Score = 35.4 bits (80), Expect = 0.054
Identities = 28/99 (28%), Positives = 48/99 (48%), Gaps = 6/99 (6%)
Query: 163 EGTSQPEPSCSAVRITANKNYRSKTSQEGALKKMHEEEHHQQMSILQLQLIQMN-EVHVA 221
E Q C R NK R K + K++ +E+ ++ L+ QL +M E+
Sbjct: 960 EKIRQKVDDCERCREFFNKEGRVKGIS--STKEVLDEDTDEEKETLKNQLREMELELAQT 1017
Query: 222 KIQQIERECEMAEEEHRIKM---EVLNKKKMYWERKLQT 257
K+Q +E EC++ + EH + + EV KK ++ R L +
Sbjct: 1018 KLQLVEAECKIQDLEHHLGLALNEVQAAKKTWFNRTLSS 1056
>gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo
sapiens]
Length = 1293
Score = 35.0 bits (79), Expect = 0.071
Identities = 17/68 (25%), Positives = 34/68 (50%)
Query: 175 VRITANKNYRSKTSQEGALKKMHEEEHHQQMSILQLQLIQMNEVHVAKIQQIERECEMAE 234
+ + + + QE AL+++ E ++ Q +L++ E AK + E E +
Sbjct: 796 IALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRL 855
Query: 235 EEHRIKME 242
EE+R++ME
Sbjct: 856 EENRLRME 863
>gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo
sapiens]
Length = 1320
Score = 35.0 bits (79), Expect = 0.071
Identities = 17/68 (25%), Positives = 34/68 (50%)
Query: 175 VRITANKNYRSKTSQEGALKKMHEEEHHQQMSILQLQLIQMNEVHVAKIQQIERECEMAE 234
+ + + + QE AL+++ E ++ Q +L++ E AK + E E +
Sbjct: 823 IALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRL 882
Query: 235 EEHRIKME 242
EE+R++ME
Sbjct: 883 EENRLRME 890
>gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 35.0 bits (79), Expect = 0.071
Identities = 17/68 (25%), Positives = 34/68 (50%)
Query: 175 VRITANKNYRSKTSQEGALKKMHEEEHHQQMSILQLQLIQMNEVHVAKIQQIERECEMAE 234
+ + + + QE AL+++ E ++ Q +L++ E AK + E E +
Sbjct: 802 IALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRL 861
Query: 235 EEHRIKME 242
EE+R++ME
Sbjct: 862 EENRLRME 869
>gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 35.0 bits (79), Expect = 0.071
Identities = 17/68 (25%), Positives = 34/68 (50%)
Query: 175 VRITANKNYRSKTSQEGALKKMHEEEHHQQMSILQLQLIQMNEVHVAKIQQIERECEMAE 234
+ + + + QE AL+++ E ++ Q +L++ E AK + E E +
Sbjct: 802 IALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRL 861
Query: 235 EEHRIKME 242
EE+R++ME
Sbjct: 862 EENRLRME 869
>gi|60460889 Myb protein P42POP [Homo sapiens]
Length = 399
Score = 35.0 bits (79), Expect = 0.071
Identities = 47/207 (22%), Positives = 77/207 (37%), Gaps = 20/207 (9%)
Query: 13 FSELEKSILLALVEKYKYVLECKKSDARTIALKQRTWQALAHEYNSQPSVSLRDFKQLKK 72
FS E IL+ V + L +S ++A ++R W +A + N S R ++++K
Sbjct: 20 FSFEENQILIREVRAHYPQLYGAQSRRVSVAERRRVWDGIAAKINGITSWK-RTGQEVQK 78
Query: 73 CWENIKARTKKIMAHERREKVKRSVSPLLSTHVLGKEKIASML-------PEQLYFLQSP 125
W + K RTK+ +A R + P +E+ + P + P
Sbjct: 79 RWNDFKRRTKEKLA--RVPHSTQGAGPAAEDAFSAEEETIFAILGPGVAAPGAGAGAEEP 136
Query: 126 PEEEPEYHPDASAQESFAVSNRELCDDEKEFIHFPVCEGTSQPEPSCSAVRITANKNYRS 185
P P SA V + + +D + G+S PEP S
Sbjct: 137 PAAPSSQPPPPSACPQRYVLSEDRREDRRADTSAHSKAGSSSPEPWARP----------S 186
Query: 186 KTSQEGALKKMHEEEHHQQMSILQLQL 212
T QEG + E E ++ +QL
Sbjct: 187 CTPQEGGCPRPKERESPPPSALQPVQL 213
>gi|219555716 synaptonemal complex central element protein 1 isoform
3 [Homo sapiens]
Length = 318
Score = 34.3 bits (77), Expect = 0.12
Identities = 48/243 (19%), Positives = 94/243 (38%), Gaps = 40/243 (16%)
Query: 42 IALKQRTWQALAHEYNSQPSVSLRDFKQLKKCWENIKARTKKIMAHERREKVKRSVSPLL 101
++ KQ T + L + S + R L++C E I A +I + +++ R
Sbjct: 102 LSKKQETLRILRLHCQEKESEAHRKHTMLQECKERISALNLQIEEEKNKQRQLRLA---- 157
Query: 102 STHVLGKEKIASMLPEQLYFLQSPPEEEPEYH-PDASAQESFAV--SNRELCDDEK---- 154
EQL L ++ ++H P+ A+E A+ S +L +EK
Sbjct: 158 -------------FEEQLEDLMGQHKDLWDFHMPERLAKEICALDSSKEQLLKEEKLVKA 204
Query: 155 --EFIHFPVCEGTSQPEPSCSAVRITANKNYRSKTSQEGALKKMHEEEHHQQMSILQLQL 212
E + +C PS T ++ ++ + A ++ +EEH + +L
Sbjct: 205 TLEDVKHQLCSLCGAEGPS------TLDEGLFLRSQEAAATVQLFQEEHRKAEELLAAA- 257
Query: 213 IQMNEVHVAKIQQIERECEMAEEEHRIKMEVLNKKKMYWERKLQTFTKEWPVSSFNRPFP 272
+ QQ++++C+ +++ + E L K M + Q+ +E P P
Sbjct: 258 -------AQRHQQLQQKCQQQQQKRQRLKEELEKHGMQVPAQAQSTQEEEAGPGDVAPRP 310
Query: 273 NSP 275
P
Sbjct: 311 GRP 313
>gi|18640754 synaptonemal complex central element protein 1 isoform
1 [Homo sapiens]
Length = 282
Score = 34.3 bits (77), Expect = 0.12
Identities = 48/243 (19%), Positives = 94/243 (38%), Gaps = 40/243 (16%)
Query: 42 IALKQRTWQALAHEYNSQPSVSLRDFKQLKKCWENIKARTKKIMAHERREKVKRSVSPLL 101
++ KQ T + L + S + R L++C E I A +I + +++ R
Sbjct: 66 LSKKQETLRILRLHCQEKESEAHRKHTMLQECKERISALNLQIEEEKNKQRQLRLA---- 121
Query: 102 STHVLGKEKIASMLPEQLYFLQSPPEEEPEYH-PDASAQESFAV--SNRELCDDEK---- 154
EQL L ++ ++H P+ A+E A+ S +L +EK
Sbjct: 122 -------------FEEQLEDLMGQHKDLWDFHMPERLAKEICALDSSKEQLLKEEKLVKA 168
Query: 155 --EFIHFPVCEGTSQPEPSCSAVRITANKNYRSKTSQEGALKKMHEEEHHQQMSILQLQL 212
E + +C PS T ++ ++ + A ++ +EEH + +L
Sbjct: 169 TLEDVKHQLCSLCGAEGPS------TLDEGLFLRSQEAAATVQLFQEEHRKAEELLAAA- 221
Query: 213 IQMNEVHVAKIQQIERECEMAEEEHRIKMEVLNKKKMYWERKLQTFTKEWPVSSFNRPFP 272
+ QQ++++C+ +++ + E L K M + Q+ +E P P
Sbjct: 222 -------AQRHQQLQQKCQQQQQKRQRLKEELEKHGMQVPAQAQSTQEEEAGPGDVAPRP 274
Query: 273 NSP 275
P
Sbjct: 275 GRP 277
>gi|41281571 synovial sarcoma, X breakpoint 2 interacting protein
[Homo sapiens]
Length = 614
Score = 33.9 bits (76), Expect = 0.16
Identities = 43/227 (18%), Positives = 97/227 (42%), Gaps = 19/227 (8%)
Query: 36 KSDARTIALKQRTWQALAHEYNSQPSVSLRDFKQLKKCWENIKARTKKIMAHERREKVKR 95
K++AR + ++ L ++Y + L + +LKK + +K +++ +++ K +
Sbjct: 246 KTEARN---EDEMYKILLNDYEYRQKQILMENAELKKVLQQMKKEMISLLSPQKK-KPRE 301
Query: 96 SVSPLLSTHVLGKEKIASMLPEQLYFLQSPPEEEPEYHPDASAQESFAVSNRELCDDEKE 155
V T + E+ A L + + S + Q S+ E D++
Sbjct: 302 RVDDSTGTVISDVEEDAGELSRESMWDLSCETVREQLTNSIRKQWRILKSHVEKLDNQVS 361
Query: 156 FIHFPVCEGTSQPEPSCSAVRITANKNYRSKTSQEGALKKMHEEEHHQQMSILQLQLIQM 215
+H EG + + + + +++ +T + + +E Q +LQ QL
Sbjct: 362 KVHL---EGFNDED-------VISRQDHEQETEKLELEIQQCKEMIKTQQQLLQQQLATA 411
Query: 216 NEVHVAKIQQIERECEMAEEEHRIKME--VLNKKKMYWERKLQTFTK 260
+ + R+C + EE+ R+K E + ++K +ER+ ++FT+
Sbjct: 412 YDDDTTSLL---RDCYLLEEKERLKEEWSLFKEQKKNFERERRSFTE 455
>gi|219555718 synaptonemal complex central element protein 1 isoform
4 [Homo sapiens]
Length = 351
Score = 33.5 bits (75), Expect = 0.21
Identities = 45/229 (19%), Positives = 91/229 (39%), Gaps = 40/229 (17%)
Query: 42 IALKQRTWQALAHEYNSQPSVSLRDFKQLKKCWENIKARTKKIMAHERREKVKRSVSPLL 101
++ KQ T + L + S + R L++C E I A +I + +++ R
Sbjct: 102 LSKKQETLRILRLHCQEKESEAHRKHTMLQECKERISALNLQIEEEKNKQRQLRLA---- 157
Query: 102 STHVLGKEKIASMLPEQLYFLQSPPEEEPEYH-PDASAQESFAV--SNRELCDDEK---- 154
EQL L ++ ++H P+ A+E A+ S +L +EK
Sbjct: 158 -------------FEEQLEDLMGQHKDLWDFHMPERLAKEICALDSSKEQLLKEEKLVKA 204
Query: 155 --EFIHFPVCEGTSQPEPSCSAVRITANKNYRSKTSQEGALKKMHEEEHHQQMSILQLQL 212
E + +C PS T ++ ++ + A ++ +EEH + +L
Sbjct: 205 TLEDVKHQLCSLCGAEGPS------TLDEGLFLRSQEAAATVQLFQEEHRKAEELLAAA- 257
Query: 213 IQMNEVHVAKIQQIERECEMAEEEHRIKMEVLNKKKMYWERKLQTFTKE 261
+ QQ++++C+ +++ + E L K M + Q+ +E
Sbjct: 258 -------AQRHQQLQQKCQQQQQKRQRLKEELEKHGMQVPAQAQSTQEE 299
>gi|56550047 uveal autoantigen with coiled-coil domains and ankyrin
repeats isoform 2 [Homo sapiens]
Length = 1403
Score = 33.1 bits (74), Expect = 0.27
Identities = 54/272 (19%), Positives = 112/272 (41%), Gaps = 52/272 (19%)
Query: 9 PAKYFSELEKSILLALVEKYKYVLECKKSDARTIALKQRTWQALAHEYNSQPSVSLRDFK 68
PA+ F ++ S+ + EK K ++E ++ + SL + +
Sbjct: 615 PAEKFENMKSSLSNEVNEKAKKLVEMEREHEK----------------------SLSEIR 652
Query: 69 QLKKCWENIKARTKKIMAHERREKVK-----------RSVSPL-LSTHVLGK--EKI--- 111
QLK+ EN+KA+ + + E E+VK + ++ L L L K EK+
Sbjct: 653 QLKRELENVKAKLAQHVKPEEHEQVKSRLEQKSGELGKKITELTLKNQTLQKEIEKVYLD 712
Query: 112 ASMLPEQLYFLQSPPEEEPEYHPDASAQESFAVSNRELCDDEKEFIHFPVCEGTSQ-PEP 170
+L EQ + L E ++ E S+ + DD ++ + + T + E
Sbjct: 713 NKLLKEQAHNLTI---EMKNHYVPLKVSEDMKKSHDAIIDD----LNRKLLDVTQKYTEK 765
Query: 171 SCSAVRITANKNYRSKTSQEGALKKMHEEEHHQQMSILQLQLIQMNEVHVAKIQQIEREC 230
++ + SK + E+H +++ L+ ++++ + ++ +++++C
Sbjct: 766 KLEMEKLLLENDSLSKDVSRLETVFVPPEKHEKEIIALKSNIVELKK----QLSELKKKC 821
Query: 231 -EMAEEEHRIKMEVLNKKKMYWERKLQTFTKE 261
E E+ H + E N KKM + + T E
Sbjct: 822 GEDQEKIHALTSENTNLKKMMSNQYVPVKTHE 853
Score = 31.6 bits (70), Expect = 0.79
Identities = 44/190 (23%), Positives = 82/190 (43%), Gaps = 35/190 (18%)
Query: 9 PAKYFSELEKSI---LLALVEKYKYVLECKKSDARTIALKQRTWQALAHEYNSQPSVSLR 65
P + L+KS+ + L E+ K + C + + +T+ + Q L ++ NS SV L
Sbjct: 1100 PLEQVEALKKSLNGTIENLKEELKSMQRCYEKEQQTVT---KLHQLLENQKNS--SVPLA 1154
Query: 66 DFKQLKKCWEN----IKA--RTKKIMAHERREKVKRSVSPLLSTHVLGKEKIASMLPEQL 119
+ Q+K+ +E IKA R K+ + + E+V + S + +T K+ + + ++
Sbjct: 1155 EHLQIKEAFEKEVGIIKASLREKEEESQNKMEEVSKLQSEVQNT----KQALKKLETREV 1210
Query: 120 YFLQSPPEEEPEYHPDASA-QESFAVSNR---ELCD-------------DEKEFIHFPVC 162
L + + S+ E A NR E+C+ DEKE +HF +
Sbjct: 1211 VDLSKYKATKSDLETQISSLNEKLANLNRKYEEVCEEVLHAKKKEISAKDEKELLHFSIE 1270
Query: 163 EGTSQPEPSC 172
+ + C
Sbjct: 1271 QEIKDQKERC 1280
>gi|59850762 uveal autoantigen with coiled-coil domains and ankyrin
repeats isoform 1 [Homo sapiens]
Length = 1416
Score = 33.1 bits (74), Expect = 0.27
Identities = 54/272 (19%), Positives = 112/272 (41%), Gaps = 52/272 (19%)
Query: 9 PAKYFSELEKSILLALVEKYKYVLECKKSDARTIALKQRTWQALAHEYNSQPSVSLRDFK 68
PA+ F ++ S+ + EK K ++E ++ + SL + +
Sbjct: 628 PAEKFENMKSSLSNEVNEKAKKLVEMEREHEK----------------------SLSEIR 665
Query: 69 QLKKCWENIKARTKKIMAHERREKVK-----------RSVSPL-LSTHVLGK--EKI--- 111
QLK+ EN+KA+ + + E E+VK + ++ L L L K EK+
Sbjct: 666 QLKRELENVKAKLAQHVKPEEHEQVKSRLEQKSGELGKKITELTLKNQTLQKEIEKVYLD 725
Query: 112 ASMLPEQLYFLQSPPEEEPEYHPDASAQESFAVSNRELCDDEKEFIHFPVCEGTSQ-PEP 170
+L EQ + L E ++ E S+ + DD ++ + + T + E
Sbjct: 726 NKLLKEQAHNLTI---EMKNHYVPLKVSEDMKKSHDAIIDD----LNRKLLDVTQKYTEK 778
Query: 171 SCSAVRITANKNYRSKTSQEGALKKMHEEEHHQQMSILQLQLIQMNEVHVAKIQQIEREC 230
++ + SK + E+H +++ L+ ++++ + ++ +++++C
Sbjct: 779 KLEMEKLLLENDSLSKDVSRLETVFVPPEKHEKEIIALKSNIVELKK----QLSELKKKC 834
Query: 231 -EMAEEEHRIKMEVLNKKKMYWERKLQTFTKE 261
E E+ H + E N KKM + + T E
Sbjct: 835 GEDQEKIHALTSENTNLKKMMSNQYVPVKTHE 866
Score = 31.6 bits (70), Expect = 0.79
Identities = 44/190 (23%), Positives = 82/190 (43%), Gaps = 35/190 (18%)
Query: 9 PAKYFSELEKSI---LLALVEKYKYVLECKKSDARTIALKQRTWQALAHEYNSQPSVSLR 65
P + L+KS+ + L E+ K + C + + +T+ + Q L ++ NS SV L
Sbjct: 1113 PLEQVEALKKSLNGTIENLKEELKSMQRCYEKEQQTVT---KLHQLLENQKNS--SVPLA 1167
Query: 66 DFKQLKKCWEN----IKA--RTKKIMAHERREKVKRSVSPLLSTHVLGKEKIASMLPEQL 119
+ Q+K+ +E IKA R K+ + + E+V + S + +T K+ + + ++
Sbjct: 1168 EHLQIKEAFEKEVGIIKASLREKEEESQNKMEEVSKLQSEVQNT----KQALKKLETREV 1223
Query: 120 YFLQSPPEEEPEYHPDASA-QESFAVSNR---ELCD-------------DEKEFIHFPVC 162
L + + S+ E A NR E+C+ DEKE +HF +
Sbjct: 1224 VDLSKYKATKSDLETQISSLNEKLANLNRKYEEVCEEVLHAKKKEISAKDEKELLHFSIE 1283
Query: 163 EGTSQPEPSC 172
+ + C
Sbjct: 1284 QEIKDQKERC 1293
>gi|37537558 nuclear apoptosis inducing factor 1 [Homo sapiens]
Length = 327
Score = 33.1 bits (74), Expect = 0.27
Identities = 19/77 (24%), Positives = 37/77 (48%), Gaps = 1/77 (1%)
Query: 13 FSELEKSILLALVEKYKYVLECKKSDARTIALKQRTWQALAHEYNSQPSVSLRDFKQLKK 72
FSE E I++ +E K++L + +A K W + N+ + R+ ++KK
Sbjct: 12 FSEREVEIIVEELELKKHLLVNHFNAGVPLAAKSAAWHGILRRVNA-VATCRRELPEVKK 70
Query: 73 CWENIKARTKKIMAHER 89
W ++K ++ +A R
Sbjct: 71 KWSDLKTEVRRKVAQVR 87
>gi|4759082 serum deprivation response protein [Homo sapiens]
Length = 425
Score = 32.3 bits (72), Expect = 0.46
Identities = 40/180 (22%), Positives = 74/180 (41%), Gaps = 20/180 (11%)
Query: 63 SLRDFKQLKKCW--ENIKARTKK----IMAHERREKVKRSVSPLLSTHVLGKEKIASMLP 116
SL+ LKK + +NI+ + K I++ ERREK+K+S++ GK + P
Sbjct: 235 SLKKVDSLKKAFSRQNIEKKMNKLGTKIVSVERREKIKKSLTSNHQKISSGKSSPFKVSP 294
Query: 117 EQLYFLQSPPEEEPEYHPDASAQESFAVSNRELCDDEKEFIHFPVCEGTSQPEPSCSAVR 176
L F + E + + + E S + D E+E EG S+ + + V
Sbjct: 295 --LTFGRKKVREGESHAENETKSEDLPSSEQMPNDQEEE----SFAEGHSEASLASALVE 348
Query: 177 ITANKNYRSKTSQEGALKKMH--------EEEHHQQMSILQLQLIQMNEVHVAKIQQIER 228
+ K + G+ M E+E + +++ Q Q ++ + ++ ER
Sbjct: 349 GEIAEEAAEKATSRGSNSGMDSNIDLTIVEDEEEESVALEQAQKVRYEGSYALTSEEAER 408
>gi|223671870 inhibitor of kappa light polypeptide gene enhancer in
B-cells, kinase gamma isoform b [Homo sapiens]
Length = 487
Score = 32.0 bits (71), Expect = 0.60
Identities = 45/223 (20%), Positives = 92/223 (41%), Gaps = 21/223 (9%)
Query: 29 KYVLECKKSDARTIALKQRTWQALAHEYNSQPSVSLRDFKQLKKCWE-------NIKART 81
K L CK +AR + + + + Q +LR+ + LK+C + ++KA+
Sbjct: 158 KEFLMCKFQEARKLVERLGLEKL---DLKRQKEQALREVEHLKRCQQQMAEDKASVKAQV 214
Query: 82 KKIMAHERREKVKRSVSPLLSTHVLGKEKIASMLPEQLYFLQSPPEEEPEYHPDASAQES 141
++ + + + + + G+ + AS EQ L+S E + H S
Sbjct: 215 TSLLGELQESQSRLEAATKECQALEGRARAAS---EQARQLESEREALQQQH-------S 264
Query: 142 FAVSNRELCDDEKEFIHFPVCEGTSQPEPSCSAVRITANKNYRSKTSQEGALKKMHEEEH 201
V + E + S+ + + +++ ++ ++ + + E +
Sbjct: 265 VQVDQLRMQGQSVEAALRMERQAASEEKRKLAQLQVAYHQLFQEYDNHIKSSVVGSERKR 324
Query: 202 HQQMSILQLQLIQMNEVHVAKIQQIERECEMAEEEHRIKMEVL 244
Q+ L+ QL Q E VAK + I++ E A E+H+I ME +
Sbjct: 325 GMQLEDLKQQLQQAEEALVAKQEVIDKLKEEA-EQHKIVMETV 366
>gi|4504631 inhibitor of kappa light polypeptide gene enhancer in
B-cells, kinase gamma isoform a [Homo sapiens]
Length = 419
Score = 32.0 bits (71), Expect = 0.60
Identities = 45/223 (20%), Positives = 92/223 (41%), Gaps = 21/223 (9%)
Query: 29 KYVLECKKSDARTIALKQRTWQALAHEYNSQPSVSLRDFKQLKKCWE-------NIKART 81
K L CK +AR + + + + Q +LR+ + LK+C + ++KA+
Sbjct: 90 KEFLMCKFQEARKLVERLGLEKL---DLKRQKEQALREVEHLKRCQQQMAEDKASVKAQV 146
Query: 82 KKIMAHERREKVKRSVSPLLSTHVLGKEKIASMLPEQLYFLQSPPEEEPEYHPDASAQES 141
++ + + + + + G+ + AS EQ L+S E + H S
Sbjct: 147 TSLLGELQESQSRLEAATKECQALEGRARAAS---EQARQLESEREALQQQH-------S 196
Query: 142 FAVSNRELCDDEKEFIHFPVCEGTSQPEPSCSAVRITANKNYRSKTSQEGALKKMHEEEH 201
V + E + S+ + + +++ ++ ++ + + E +
Sbjct: 197 VQVDQLRMQGQSVEAALRMERQAASEEKRKLAQLQVAYHQLFQEYDNHIKSSVVGSERKR 256
Query: 202 HQQMSILQLQLIQMNEVHVAKIQQIERECEMAEEEHRIKMEVL 244
Q+ L+ QL Q E VAK + I++ E A E+H+I ME +
Sbjct: 257 GMQLEDLKQQLQQAEEALVAKQEVIDKLKEEA-EQHKIVMETV 298
>gi|153792133 inhibitor of kappa light polypeptide gene enhancer in
B-cells, kinase gamma isoform a [Homo sapiens]
Length = 419
Score = 32.0 bits (71), Expect = 0.60
Identities = 45/223 (20%), Positives = 92/223 (41%), Gaps = 21/223 (9%)
Query: 29 KYVLECKKSDARTIALKQRTWQALAHEYNSQPSVSLRDFKQLKKCWE-------NIKART 81
K L CK +AR + + + + Q +LR+ + LK+C + ++KA+
Sbjct: 90 KEFLMCKFQEARKLVERLGLEKL---DLKRQKEQALREVEHLKRCQQQMAEDKASVKAQV 146
Query: 82 KKIMAHERREKVKRSVSPLLSTHVLGKEKIASMLPEQLYFLQSPPEEEPEYHPDASAQES 141
++ + + + + + G+ + AS EQ L+S E + H S
Sbjct: 147 TSLLGELQESQSRLEAATKECQALEGRARAAS---EQARQLESEREALQQQH-------S 196
Query: 142 FAVSNRELCDDEKEFIHFPVCEGTSQPEPSCSAVRITANKNYRSKTSQEGALKKMHEEEH 201
V + E + S+ + + +++ ++ ++ + + E +
Sbjct: 197 VQVDQLRMQGQSVEAALRMERQAASEEKRKLAQLQVAYHQLFQEYDNHIKSSVVGSERKR 256
Query: 202 HQQMSILQLQLIQMNEVHVAKIQQIERECEMAEEEHRIKMEVL 244
Q+ L+ QL Q E VAK + I++ E A E+H+I ME +
Sbjct: 257 GMQLEDLKQQLQQAEEALVAKQEVIDKLKEEA-EQHKIVMETV 298
>gi|56676397 ankyrin repeat domain 11 [Homo sapiens]
Length = 2663
Score = 32.0 bits (71), Expect = 0.60
Identities = 21/91 (23%), Positives = 49/91 (53%), Gaps = 5/91 (5%)
Query: 176 RITANKNYRSKTSQEGALKKMHEEEHHQQMSILQLQLIQMNEVHVAKIQQIERECEMAEE 235
R+T+ +Y S+ S +LK + + + H++ + L + + ++++E ++ ++
Sbjct: 572 RLTSESDYSSEGSSVESLKPVRKRQEHRKRASLSEKKSPFLSSAEGAVPKLDKEGKVVKK 631
Query: 236 EHRIKMEVLNKKK----MYWERKLQTFTKEW 262
H+ K + NK+K + E KL++FT E+
Sbjct: 632 -HKTKHKHKNKEKGQCSISQELKLKSFTYEY 661
>gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo
sapiens]
Length = 2168
Score = 32.0 bits (71), Expect = 0.60
Identities = 21/66 (31%), Positives = 39/66 (59%), Gaps = 2/66 (3%)
Query: 192 ALKKMHEEE-HHQQMSILQLQLIQMNEVHVAKIQQIERECEMAEEEHRIKMEVLNKKKMY 250
A K++ E+E QQ +L+ Q + H+ ++ +E + AEE+ R+K E ++K++
Sbjct: 983 AEKRIKEKEMRRQQAVLLKHQERERRRQHMMLMKAMEAR-KKAEEKERLKQEKRDEKRLN 1041
Query: 251 WERKLQ 256
ERKL+
Sbjct: 1042 KERKLE 1047
>gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens]
Length = 1684
Score = 31.6 bits (70), Expect = 0.79
Identities = 13/50 (26%), Positives = 33/50 (66%), Gaps = 1/50 (2%)
Query: 200 EHHQQ-MSILQLQLIQMNEVHVAKIQQIERECEMAEEEHRIKMEVLNKKK 248
+H+Q+ ++ LQ +L+Q+ +H +++++ + E + +EH ++ LN+ K
Sbjct: 228 QHYQKNINSLQEELLQLKAIHQEEVKELMCQIEASAKEHEAEINKLNELK 277
>gi|82697315 RUN and FYVE domain containing 3 isoform 1 [Homo
sapiens]
Length = 620
Score = 31.2 bits (69), Expect = 1.0
Identities = 37/182 (20%), Positives = 67/182 (36%), Gaps = 6/182 (3%)
Query: 57 NSQPSVSLRDFKQLKKCWENIKARTKKIMAHERREKVKRSVSPLLSTHVLGKEKIASMLP 116
N Q V + K E A + I E E+VK S +L ++ G ++ +
Sbjct: 280 NLQAKVDALEKSNTKLTEELAVANNRIITLQEEMERVKEESSYILESNRKGPKQDRTAEG 339
Query: 117 EQLYFLQSPPEEEPEYHPDASAQESFAVSNRELCDDEKEFIHFPVCEGTSQPEPSCSAVR 176
+ L + +EE + D + +S R+ + + + VCE + V
Sbjct: 340 QALSEARKHLKEETQLRLDVEKELEMQISMRQEMELAMKMLEKDVCEKQD------ALVS 393
Query: 177 ITANKNYRSKTSQEGALKKMHEEEHHQQMSILQLQLIQMNEVHVAKIQQIERECEMAEEE 236
+ + E A K + +Q S L +L + A I+Q+E+ AE
Sbjct: 394 LRQQLDDLRALKHELAFKLQSSDLGVKQKSELNSRLEEKTNQMAATIKQLEQRLRQAERS 453
Query: 237 HR 238
+
Sbjct: 454 RQ 455
>gi|148839294 Ca2+-dependent activator protein for secretion 2
isoform a [Homo sapiens]
Length = 1296
Score = 31.2 bits (69), Expect = 1.0
Identities = 17/64 (26%), Positives = 36/64 (56%), Gaps = 1/64 (1%)
Query: 1 MQNNEIIKPAKYFSELEKSILLALVEKYKYVLECKKSDARTIALKQRTWQALAHEYNSQP 60
++N+ ++ K+ L++ I + LV +Y ++E + + +Q TWQ + + NS P
Sbjct: 912 LRNDTLLCNGKFHKHLQE-IFVPLVVRYVDLMESSIAQSIHRGFEQETWQPVKNIANSLP 970
Query: 61 SVSL 64
+V+L
Sbjct: 971 NVAL 974
>gi|115495445 ankyrin repeat domain 30A [Homo sapiens]
Length = 1341
Score = 30.8 bits (68), Expect = 1.3
Identities = 49/247 (19%), Positives = 88/247 (35%), Gaps = 54/247 (21%)
Query: 26 EKYKYVLECKKSDARTIALKQRTWQALAHEYNSQPSVSLRDFKQLKKCWENIK------- 78
E Y+L + IA+ + L H+Y + + D K LK+ ++
Sbjct: 1039 ENENYLLHENCMLKKEIAMLKLEIATLKHQYQEKENKYFEDIKILKEKNAELQMTLKLKE 1098
Query: 79 -ARTKKIMAHERREKVKRSVSPLLSTHVLGKE--------------KIASMLPEQLYFLQ 123
+ TK+ + + KV + + +L++ + K+ ++AS + + +
Sbjct: 1099 ESLTKRASQYSGQLKVLIAENTMLTSKLKEKQDKEILEAEIESHHPRLASAVQDHDQIVT 1158
Query: 124 SPPEEEPEYH--PDASAQESFAVSNRELCDDEKEFIHFPVCEGTSQPEPSCSAVRITANK 181
S +EP +H DA Q V + E +H P+ E + + + N
Sbjct: 1159 SRKSQEPAFHIAGDACLQRKMNVDVSSTIYNN-EVLHQPLSEAQRKSKS------LKINL 1211
Query: 182 NYRSKTSQEGALKKMHEEEHHQQMSILQLQLIQMNEVHVAKIQQIERECEMAEEEHRIKM 241
NY +E L H A+ Q E +C+M E EH +
Sbjct: 1212 NYAGDALRENTLVSEH-----------------------AQRDQRETQCQMKEAEHMYQN 1248
Query: 242 EVLNKKK 248
E N K
Sbjct: 1249 EQDNVNK 1255
>gi|14042947 testis-specific serine kinase 1 [Homo sapiens]
Length = 367
Score = 30.8 bits (68), Expect = 1.3
Identities = 25/101 (24%), Positives = 41/101 (40%), Gaps = 14/101 (13%)
Query: 70 LKKCWENIKARTKKIMAHERREKVKRSVSPLLSTHVLGKEKIASML-PEQLYFLQSPPEE 128
L CW KAR +A + + R PL + +K A+ L PE ++ P+
Sbjct: 267 LSHCWMQPKARGSPSVAINKEGESSRGTEPLWTPEPGSDKKSATKLEPEG----EAQPQA 322
Query: 129 EPEYHPDASAQESFAVSNRELCDDEKEFIHFPVCEGTSQPE 169
+PE P+ +A + + E + FP T + E
Sbjct: 323 QPETKPEGTAMQ---------MSRQSEILGFPSKPSTMETE 354
>gi|115648142 centrosomal protein 164kDa [Homo sapiens]
Length = 1460
Score = 30.8 bits (68), Expect = 1.3
Identities = 53/257 (20%), Positives = 113/257 (43%), Gaps = 46/257 (17%)
Query: 1 MQNNEIIKPAKYFSE-----LEKSILLALVEKYKYVLECKKSDARTIALK--QRTWQALA 53
+++ E + P + SE +E+++ L + +++LE K+ + + K Q + +
Sbjct: 575 VRSTEPVAPPEQLSEAALKAMEEAVAQVLEQDQRHLLESKQEKMQQLREKLCQEEEEEIL 634
Query: 54 --HEYNSQPSVSLRDFKQLKKCWENIKARTKKIMAHERREKVKRSVSPLLSTHVLGKEKI 111
H+ Q SLR+ +L+K E +AR M E +++ + + S+ +++I
Sbjct: 635 RLHQQKEQSLSSLRE--RLQKAIEEEEAR----MREEESQRLSWLRAQVQSSTQADEDQI 688
Query: 112 ASMLPEQLYFLQSPPEEEPEYHPDASAQESFAVSNRELCDDEKEFIHFPVCEGTSQPEPS 171
+ L L+ E + + + + S NR++ + KE I E + + E +
Sbjct: 689 RAEQEASLQKLREELESQQK-----AERASLEQKNRQMLEQLKEEI-----EASEKSEQA 738
Query: 172 CSAVRITANKNYRSKTSQEGALKKMHEE-EHHQQMSILQLQLIQMNEVHVAKIQQIEREC 230
++E AL+++ E+ E ++ ++ L+ + H A ++ER C
Sbjct: 739 AL------------NAAKEKALQQLREQLEGERKEAVATLE-----KEHSA---ELERLC 778
Query: 231 EMAEEEHRIKMEVLNKK 247
E +HR + L KK
Sbjct: 779 SSLEAKHREVVSSLQKK 795
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.127 0.367
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,895,096
Number of Sequences: 37866
Number of extensions: 486033
Number of successful extensions: 2319
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 24
Number of HSP's successfully gapped in prelim test: 117
Number of HSP's that attempted gapping in prelim test: 2203
Number of HSP's gapped (non-prelim): 241
length of query: 275
length of database: 18,247,518
effective HSP length: 101
effective length of query: 174
effective length of database: 14,423,052
effective search space: 2509611048
effective search space used: 2509611048
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.5 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.