Guide to the Human Genome
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Search of human proteins with 18034690

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|18034690 hypothetical protein LOC25980 [Homo sapiens]
         (384 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|18034690 hypothetical protein LOC25980 [Homo sapiens]              779   0.0  
gi|55769583 progesterone-induced blocking factor 1 [Homo sapiens]      38   0.013
gi|197313748 SET domain containing 2 [Homo sapiens]                    31   1.6  
gi|239756507 PREDICTED: similar to Acyl-coenzyme A synthetase AC...    30   2.8  
gi|239756505 PREDICTED: similar to Acyl-coenzyme A synthetase AC...    30   2.8  
gi|58082049 acyl-CoA synthetase medium-chain family member 2A [H...    30   2.8  
gi|157311624 acyl-CoA synthetase medium-chain family member 2B [...    30   2.8  
gi|157311622 acyl-CoA synthetase medium-chain family member 2B [...    30   2.8  
gi|82659109 retinoblastoma-associated factor 600 [Homo sapiens]        30   2.8  
gi|239752532 PREDICTED: similar to Putative uncharacterized prot...    30   3.7  
gi|226442893 jumonji domain containing 2C isoform 3 [Homo sapiens]     30   4.8  
gi|226442897 jumonji domain containing 2C isoform 4 [Homo sapiens]     30   4.8  
gi|226442889 jumonji domain containing 2C isoform 2 [Homo sapiens]     30   4.8  
gi|109255247 jumonji domain containing 2C isoform 1 [Homo sapiens]     30   4.8  
gi|44917604 SLIT-ROBO Rho GTPase activating protein 1 [Homo sapi...    29   8.1  
gi|4557367 bleomycin hydrolase [Homo sapiens]                          29   8.1  

>gi|18034690 hypothetical protein LOC25980 [Homo sapiens]
          Length = 384

 Score =  779 bits (2011), Expect = 0.0
 Identities = 384/384 (100%), Positives = 384/384 (100%)

Query: 1   MAAVQMDPELAKRLFFEGATVVILNMPKGTEFGIDYNSWEVGPKFRGVKMIPPGIHFLHY 60
           MAAVQMDPELAKRLFFEGATVVILNMPKGTEFGIDYNSWEVGPKFRGVKMIPPGIHFLHY
Sbjct: 1   MAAVQMDPELAKRLFFEGATVVILNMPKGTEFGIDYNSWEVGPKFRGVKMIPPGIHFLHY 60

Query: 61  SSVDKANPKEVGPRMGFFLSLHQRGLTVLRWSTLREEVDLSPAPESEVEAMRANLQELDQ 120
           SSVDKANPKEVGPRMGFFLSLHQRGLTVLRWSTLREEVDLSPAPESEVEAMRANLQELDQ
Sbjct: 61  SSVDKANPKEVGPRMGFFLSLHQRGLTVLRWSTLREEVDLSPAPESEVEAMRANLQELDQ 120

Query: 121 FLGPYPYATLKKWISLTNFISEATVEKLQPENRQICAFSDVLPVLSMKHTKDRVGQNLPR 180
           FLGPYPYATLKKWISLTNFISEATVEKLQPENRQICAFSDVLPVLSMKHTKDRVGQNLPR
Sbjct: 121 FLGPYPYATLKKWISLTNFISEATVEKLQPENRQICAFSDVLPVLSMKHTKDRVGQNLPR 180

Query: 181 CGIECKSYQEGLARLPEMKPRAGTEIRFSELPTQMFPEGATPAEITKHSMDLSYALETVL 240
           CGIECKSYQEGLARLPEMKPRAGTEIRFSELPTQMFPEGATPAEITKHSMDLSYALETVL
Sbjct: 181 CGIECKSYQEGLARLPEMKPRAGTEIRFSELPTQMFPEGATPAEITKHSMDLSYALETVL 240

Query: 241 NKQFPSSPQDVLGELQFAFVCFLLGNVYEAFEHWKRLLNLLCRSEAAMMKHHTLYINLIS 300
           NKQFPSSPQDVLGELQFAFVCFLLGNVYEAFEHWKRLLNLLCRSEAAMMKHHTLYINLIS
Sbjct: 241 NKQFPSSPQDVLGELQFAFVCFLLGNVYEAFEHWKRLLNLLCRSEAAMMKHHTLYINLIS 300

Query: 301 ILYHQLGEIPADFFVDIVSQDNFLTSTLQVFFSSACSIAVDATLRKKAEKFQAHLTKKFR 360
           ILYHQLGEIPADFFVDIVSQDNFLTSTLQVFFSSACSIAVDATLRKKAEKFQAHLTKKFR
Sbjct: 301 ILYHQLGEIPADFFVDIVSQDNFLTSTLQVFFSSACSIAVDATLRKKAEKFQAHLTKKFR 360

Query: 361 WDFAAEPEDCAPVVVELPEGIEMG 384
           WDFAAEPEDCAPVVVELPEGIEMG
Sbjct: 361 WDFAAEPEDCAPVVVELPEGIEMG 384


>gi|55769583 progesterone-induced blocking factor 1 [Homo sapiens]
          Length = 757

 Score = 38.1 bits (87), Expect = 0.013
 Identities = 33/124 (26%), Positives = 56/124 (45%), Gaps = 17/124 (13%)

Query: 94  LREEVDLSPAP-ESEVEAMRANLQELDQFLGPYPYATLKKWISLTNFISEATVEKLQPEN 152
           LRE  D + A  E  V A +  L++ DQ L  Y    L     +T F+ ++ ++  + E 
Sbjct: 410 LREARDNAVAEKERAVMAEKDALEKHDQLLDRYRELQLSTESKVTEFLHQSKLKSFESER 469

Query: 153 RQICAFSDVLPVLSMKHTKDRVGQNLPRCGIECKSYQEGLARLPE--MKPRAGTEIRFSE 210
            Q+               ++   +NL +C +EC+ YQ+ L  L +     +A +E R +E
Sbjct: 470 VQLL--------------QEETARNLTQCQLECEKYQKKLEVLTKEFYSLQASSEKRITE 515

Query: 211 LPTQ 214
           L  Q
Sbjct: 516 LQAQ 519


>gi|197313748 SET domain containing 2 [Homo sapiens]
          Length = 2564

 Score = 31.2 bits (69), Expect = 1.6
 Identities = 34/107 (31%), Positives = 48/107 (44%), Gaps = 7/107 (6%)

Query: 147  KLQPENRQICAFSDVLPVLSMKHTKDRVGQ--NLP-RCGIECKSYQEGLARLPEMKPRAG 203
            K+  EN    A SD    L  K  K+ + Q  N+P     E +S Q    +LPE K  + 
Sbjct: 1882 KIISENSMDSAISDATSELEGKDGKEDLDQLENVPVEEEEELQSQQLLPQQLPECKVDSE 1941

Query: 204  TEIRFSELPTQMFPEGATPAEITKHSMDLSYALETVLNKQFPSSPQD 250
            T I  S+LPT    E    AEI     +    LE  +N++ PS  ++
Sbjct: 1942 TNIEASKLPTS---EPEADAEIEPKESN-GTKLEEPINEETPSQDEE 1984


>gi|239756507 PREDICTED: similar to Acyl-coenzyme A synthetase
           ACSM2B, mitochondrial isoform 2 [Homo sapiens]
          Length = 571

 Score = 30.4 bits (67), Expect = 2.8
 Identities = 17/43 (39%), Positives = 21/43 (48%), Gaps = 2/43 (4%)

Query: 273 HWKRLLNLLCRSEAAMMKHHTLYINLISILYHQLG--EIPADF 313
           HW R +  LC      M   TLYIN   ++  Q G  E+PA F
Sbjct: 2   HWLRKVQGLCTLWGTQMSSRTLYINSRQLVSLQWGHQEVPAKF 44


>gi|239756505 PREDICTED: similar to Acyl-coenzyme A synthetase
           ACSM2B, mitochondrial isoform 1 [Homo sapiens]
          Length = 571

 Score = 30.4 bits (67), Expect = 2.8
 Identities = 17/43 (39%), Positives = 21/43 (48%), Gaps = 2/43 (4%)

Query: 273 HWKRLLNLLCRSEAAMMKHHTLYINLISILYHQLG--EIPADF 313
           HW R +  LC      M   TLYIN   ++  Q G  E+PA F
Sbjct: 2   HWLRKVQGLCTLWGTQMSSRTLYINSRQLVSLQWGHQEVPAKF 44


>gi|58082049 acyl-CoA synthetase medium-chain family member 2A [Homo
           sapiens]
          Length = 577

 Score = 30.4 bits (67), Expect = 2.8
 Identities = 17/43 (39%), Positives = 21/43 (48%), Gaps = 2/43 (4%)

Query: 273 HWKRLLNLLCRSEAAMMKHHTLYINLISILYHQLG--EIPADF 313
           HW R +  LC      M   TLYIN   ++  Q G  E+PA F
Sbjct: 2   HWLRKVQGLCTLWGTQMSSRTLYINSRQLVSLQWGHQEVPAKF 44


>gi|157311624 acyl-CoA synthetase medium-chain family member 2B
           [Homo sapiens]
          Length = 577

 Score = 30.4 bits (67), Expect = 2.8
 Identities = 17/43 (39%), Positives = 21/43 (48%), Gaps = 2/43 (4%)

Query: 273 HWKRLLNLLCRSEAAMMKHHTLYINLISILYHQLG--EIPADF 313
           HW R +  LC      M   TLYIN   ++  Q G  E+PA F
Sbjct: 2   HWLRKVQGLCTLWGTQMSSRTLYINSRQLVSLQWGHQEVPAKF 44


>gi|157311622 acyl-CoA synthetase medium-chain family member 2B
           [Homo sapiens]
          Length = 577

 Score = 30.4 bits (67), Expect = 2.8
 Identities = 17/43 (39%), Positives = 21/43 (48%), Gaps = 2/43 (4%)

Query: 273 HWKRLLNLLCRSEAAMMKHHTLYINLISILYHQLG--EIPADF 313
           HW R +  LC      M   TLYIN   ++  Q G  E+PA F
Sbjct: 2   HWLRKVQGLCTLWGTQMSSRTLYINSRQLVSLQWGHQEVPAKF 44


>gi|82659109 retinoblastoma-associated factor 600 [Homo sapiens]
          Length = 5183

 Score = 30.4 bits (67), Expect = 2.8
 Identities = 27/93 (29%), Positives = 41/93 (44%), Gaps = 12/93 (12%)

Query: 91   WSTLREEVDLSPAPESEVEAMRANLQELDQFLGPYPYATLKKWISLTNFISEATVEKLQP 150
            +S +  E D   + E     + A LQ +D       YA+  +   L NF  E T EK  P
Sbjct: 1139 FSKMAAETDPHKSSEITKNLLPATLQLIDT------YASFTRAYLLQNFNEEGTTEK--P 1190

Query: 151  ENRQICAFSDVLPVLSMKHTKDRVG----QNLP 179
               ++  F+ VL + S +   + +G    QNLP
Sbjct: 1191 SKEKLQGFAAVLAIGSSRCKANTLGPTLVQNLP 1223


>gi|239752532 PREDICTED: similar to Putative uncharacterized protein
           FLJ46348, partial [Homo sapiens]
          Length = 178

 Score = 30.0 bits (66), Expect = 3.7
 Identities = 19/64 (29%), Positives = 28/64 (43%)

Query: 159 SDVLPVLSMKHTKDRVGQNLPRCGIECKSYQEGLARLPEMKPRAGTEIRFSELPTQMFPE 218
           S  LPV S+  ++ +VG   P  G+   S    + R+   +PR+      S  P Q  P 
Sbjct: 111 SSCLPVTSVGPSRPQVGLPRPSSGLSAASPSAKVPRVSLSRPRSSCLPVASFGPAQFMPP 170

Query: 219 GATP 222
           G  P
Sbjct: 171 GGLP 174


>gi|226442893 jumonji domain containing 2C isoform 3 [Homo sapiens]
          Length = 813

 Score = 29.6 bits (65), Expect = 4.8
 Identities = 26/93 (27%), Positives = 37/93 (39%), Gaps = 2/93 (2%)

Query: 292 HTLYINLISILYHQLGEIPADFFVDIVSQDNFLTSTLQVFFSSACSIAVDATLRKKAEKF 351
           HT  ++L SI Y   GE P  ++         L    Q FF S+ S   DA LR K    
Sbjct: 190 HTEDMDLYSINYLHFGE-PKSWYAIPPEHGKRLERLAQGFFPSS-SQGCDAFLRHKMTLI 247

Query: 352 QAHLTKKFRWDFAAEPEDCAPVVVELPEGIEMG 384
              + KK+   F    ++    ++  P G   G
Sbjct: 248 SPSVLKKYGIPFDKITQEAGEFMITFPYGYHAG 280


>gi|226442897 jumonji domain containing 2C isoform 4 [Homo sapiens]
          Length = 835

 Score = 29.6 bits (65), Expect = 4.8
 Identities = 26/93 (27%), Positives = 37/93 (39%), Gaps = 2/93 (2%)

Query: 292 HTLYINLISILYHQLGEIPADFFVDIVSQDNFLTSTLQVFFSSACSIAVDATLRKKAEKF 351
           HT  ++L SI Y   GE P  ++         L    Q FF S+ S   DA LR K    
Sbjct: 212 HTEDMDLYSINYLHFGE-PKSWYAIPPEHGKRLERLAQGFFPSS-SQGCDAFLRHKMTLI 269

Query: 352 QAHLTKKFRWDFAAEPEDCAPVVVELPEGIEMG 384
              + KK+   F    ++    ++  P G   G
Sbjct: 270 SPSVLKKYGIPFDKITQEAGEFMITFPYGYHAG 302


>gi|226442889 jumonji domain containing 2C isoform 2 [Homo sapiens]
          Length = 1047

 Score = 29.6 bits (65), Expect = 4.8
 Identities = 26/93 (27%), Positives = 37/93 (39%), Gaps = 2/93 (2%)

Query: 292 HTLYINLISILYHQLGEIPADFFVDIVSQDNFLTSTLQVFFSSACSIAVDATLRKKAEKF 351
           HT  ++L SI Y   GE P  ++         L    Q FF S+ S   DA LR K    
Sbjct: 190 HTEDMDLYSINYLHFGE-PKSWYAIPPEHGKRLERLAQGFFPSS-SQGCDAFLRHKMTLI 247

Query: 352 QAHLTKKFRWDFAAEPEDCAPVVVELPEGIEMG 384
              + KK+   F    ++    ++  P G   G
Sbjct: 248 SPSVLKKYGIPFDKITQEAGEFMITFPYGYHAG 280


>gi|109255247 jumonji domain containing 2C isoform 1 [Homo sapiens]
          Length = 1056

 Score = 29.6 bits (65), Expect = 4.8
 Identities = 26/93 (27%), Positives = 37/93 (39%), Gaps = 2/93 (2%)

Query: 292 HTLYINLISILYHQLGEIPADFFVDIVSQDNFLTSTLQVFFSSACSIAVDATLRKKAEKF 351
           HT  ++L SI Y   GE P  ++         L    Q FF S+ S   DA LR K    
Sbjct: 190 HTEDMDLYSINYLHFGE-PKSWYAIPPEHGKRLERLAQGFFPSS-SQGCDAFLRHKMTLI 247

Query: 352 QAHLTKKFRWDFAAEPEDCAPVVVELPEGIEMG 384
              + KK+   F    ++    ++  P G   G
Sbjct: 248 SPSVLKKYGIPFDKITQEAGEFMITFPYGYHAG 280


>gi|44917604 SLIT-ROBO Rho GTPase activating protein 1 [Homo
           sapiens]
          Length = 1085

 Score = 28.9 bits (63), Expect = 8.1
 Identities = 24/104 (23%), Positives = 50/104 (48%), Gaps = 10/104 (9%)

Query: 202 AGTEIRFSELPTQMFPEGATPAEITKHSMDLSYALETVLNKQF-----PSSPQDVLGELQ 256
           +G+++  +++    F  G  P    + + D++ ++  VL   F     P  P++   +L 
Sbjct: 544 SGSQVEVNDIKNS-FERGENPLADDQSNHDIN-SVAGVLKLYFRGLENPLFPKERFNDL- 600

Query: 257 FAFVCFLLGNVYEAFEHWKRLLNLLCRSEAAMMKHHTLYINLIS 300
               C  + N+YE   H ++LL  L RS   +M++   ++N +S
Sbjct: 601 --ISCIRIDNLYERALHIRKLLLTLPRSVLIVMRYLFAFLNHLS 642


>gi|4557367 bleomycin hydrolase [Homo sapiens]
          Length = 455

 Score = 28.9 bits (63), Expect = 8.1
 Identities = 23/76 (30%), Positives = 32/76 (42%), Gaps = 11/76 (14%)

Query: 207 RFSELPTQMFPEGATPA------EITKHSMD-----LSYALETVLNKQFPSSPQDVLGEL 255
           ++  +P + FPE  T        +I  H M      L   + +   K   S+ QDV+ E 
Sbjct: 156 KYGVIPKKCFPESYTTEATRRMNDILNHKMREFCIRLRNLVHSGATKGEISATQDVMMEE 215

Query: 256 QFAFVCFLLGNVYEAF 271
            F  VC  LGN  E F
Sbjct: 216 IFRVVCICLGNPPETF 231


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.136    0.412 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,201,349
Number of Sequences: 37866
Number of extensions: 685878
Number of successful extensions: 1347
Number of sequences better than 10.0: 16
Number of HSP's better than 10.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 14
Number of HSP's that attempted gapping in prelim test: 1344
Number of HSP's gapped (non-prelim): 16
length of query: 384
length of database: 18,247,518
effective HSP length: 104
effective length of query: 280
effective length of database: 14,309,454
effective search space: 4006647120
effective search space used: 4006647120
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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