Search of human proteins with 176866369

Search of human proteins with 176866369

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|176866369 KDEL (Lys-Asp-Glu-Leu) containing 1 [Homo sapiens]
         (502 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|176866369 KDEL (Lys-Asp-Glu-Leu) containing 1 [Homo sapiens]      1036   0.0  
gi|153218487 KDEL (Lys-Asp-Glu-Leu) containing 2 [Homo sapiens]       539   e-153
gi|31982953 KTEL (Lys-Tyr-Glu-Leu) containing 1 [Homo sapiens]        160   3e-39
gi|188595687 gamma filamin isoform b [Homo sapiens]                    39   0.011
gi|116805322 gamma filamin isoform a [Homo sapiens]                    39   0.011
gi|160420317 filamin A, alpha isoform 2 [Homo sapiens]                 36   0.071
gi|116063573 filamin A, alpha isoform 1 [Homo sapiens]                 36   0.071
gi|105990514 filamin B, beta (actin binding protein 278) [Homo s...    33   0.60 
gi|88702793 slit-like 2 [Homo sapiens]                                 30   3.9  
gi|226342962 synaptotagmin XIV isoform 2 [Homo sapiens]                30   5.1  
gi|226342957 synaptotagmin XIV isoform 3 [Homo sapiens]                30   5.1  
gi|226342955 synaptotagmin XIV isoform 1 [Homo sapiens]                30   5.1  
gi|144226225 synaptotagmin XIV isoform 4 [Homo sapiens]                30   5.1  
gi|14149981 transmembrane protein 117 [Homo sapiens]                   29   8.7  
gi|102467235 inner centromere protein antigens 135/155kDa isofor...    29   8.7  
gi|102467242 inner centromere protein antigens 135/155kDa isofor...    29   8.7  

>gi|176866369 KDEL (Lys-Asp-Glu-Leu) containing 1 [Homo sapiens]
          Length = 502

 Score = 1036 bits (2680), Expect = 0.0
 Identities = 502/502 (100%), Positives = 502/502 (100%)

Query: 1   MFGTLLLYCFFLATVPALAETGGERQLSPEKSEIWGPGLKADVVLPARYFYIQAVDTSGN 60
           MFGTLLLYCFFLATVPALAETGGERQLSPEKSEIWGPGLKADVVLPARYFYIQAVDTSGN
Sbjct: 1   MFGTLLLYCFFLATVPALAETGGERQLSPEKSEIWGPGLKADVVLPARYFYIQAVDTSGN 60

Query: 61  KFTSSPGEKVFQVKVSAPEEQFTRVGVQVLDRKDGSFIVRYRMYASYKNLKVEIKFQGQH 120
           KFTSSPGEKVFQVKVSAPEEQFTRVGVQVLDRKDGSFIVRYRMYASYKNLKVEIKFQGQH
Sbjct: 61  KFTSSPGEKVFQVKVSAPEEQFTRVGVQVLDRKDGSFIVRYRMYASYKNLKVEIKFQGQH 120

Query: 121 VAKSPYILKGPVYHENCDCPLQDSAAWLREMNCPETIAQIQRDLAHFPAVDPEKIAVEIP 180
           VAKSPYILKGPVYHENCDCPLQDSAAWLREMNCPETIAQIQRDLAHFPAVDPEKIAVEIP
Sbjct: 121 VAKSPYILKGPVYHENCDCPLQDSAAWLREMNCPETIAQIQRDLAHFPAVDPEKIAVEIP 180

Query: 181 KRFGQRQSLCHYTLKDNKVYIKTHGEHVGFRIFMDAILLSLTRKVKMPDVELFVNLGDWP 240
           KRFGQRQSLCHYTLKDNKVYIKTHGEHVGFRIFMDAILLSLTRKVKMPDVELFVNLGDWP
Sbjct: 181 KRFGQRQSLCHYTLKDNKVYIKTHGEHVGFRIFMDAILLSLTRKVKMPDVELFVNLGDWP 240

Query: 241 LEKKKSNSNIHPIFSWCGSTDSKDIVMPTYDLTDSVLETMGRVSLDMMSVQANTGPPWES 300
           LEKKKSNSNIHPIFSWCGSTDSKDIVMPTYDLTDSVLETMGRVSLDMMSVQANTGPPWES
Sbjct: 241 LEKKKSNSNIHPIFSWCGSTDSKDIVMPTYDLTDSVLETMGRVSLDMMSVQANTGPPWES 300

Query: 301 KNSTAVWRGRDSRKERLELVKLSRKHPELIDAAFTNFFFFKHDENLYGPIVKHISFFDFF 360
           KNSTAVWRGRDSRKERLELVKLSRKHPELIDAAFTNFFFFKHDENLYGPIVKHISFFDFF
Sbjct: 301 KNSTAVWRGRDSRKERLELVKLSRKHPELIDAAFTNFFFFKHDENLYGPIVKHISFFDFF 360

Query: 361 KHKYQINIDGTVAAYRLPYLLVGDSVVLKQDSIYYEHFYNELQPWKHYIPVKSNLSDLLE 420
           KHKYQINIDGTVAAYRLPYLLVGDSVVLKQDSIYYEHFYNELQPWKHYIPVKSNLSDLLE
Sbjct: 361 KHKYQINIDGTVAAYRLPYLLVGDSVVLKQDSIYYEHFYNELQPWKHYIPVKSNLSDLLE 420

Query: 421 KLKWAKDHDEEAKKIAKAGQEFARNNLMGDDIFCYYFKLFQEYANLQVSEPQIREGMKRV 480
           KLKWAKDHDEEAKKIAKAGQEFARNNLMGDDIFCYYFKLFQEYANLQVSEPQIREGMKRV
Sbjct: 421 KLKWAKDHDEEAKKIAKAGQEFARNNLMGDDIFCYYFKLFQEYANLQVSEPQIREGMKRV 480

Query: 481 EPQTEDDLFPCTCHRKKTKDEL 502
           EPQTEDDLFPCTCHRKKTKDEL
Sbjct: 481 EPQTEDDLFPCTCHRKKTKDEL 502


>gi|153218487 KDEL (Lys-Asp-Glu-Leu) containing 2 [Homo sapiens]
          Length = 507

 Score =  539 bits (1389), Expect = e-153
 Identities = 263/482 (54%), Positives = 359/482 (74%), Gaps = 10/482 (2%)

Query: 27  LSPEKSEIWGPGLKADVVLPARYFYIQAVDTSGNKFTSSP-GEKVFQVKV-SAPEEQFTR 84
           +S  +S +WGPGL+A VVLP RYFY+QAV++ G   T SP GE  F+V V S   ++  R
Sbjct: 27  VSAPRSLVWGPGLQAAVVLPVRYFYLQAVNSEGQNLTRSPAGETPFKVVVKSLSPKELVR 86

Query: 85  VGV-QVLDRKDGSFIVRYRMYASY-KNLKVEIKFQGQHVAKSPYILKGPVYHENCDCPLQ 142
           + V + LDR DG+F++RYRMY +  + LK+E+ +  +HVA+SPYILKGPVYHE C+CP +
Sbjct: 87  IHVPKPLDRNDGTFLMRYRMYETVDEGLKIEVLYGDEHVAQSPYILKGPVYHEYCECP-E 145

Query: 143 DSAAWLREMNCPETIAQIQRDLAHFPAVDPEKIAVEIPKRFG-QRQSLCHYTLKDNKVYI 201
           D  AW + ++CP    QI +D A FP+++ +++  E+PKRFG +R ++ HYT+ +N VY 
Sbjct: 146 DPQAWQKTLSCPTKEPQIAKDFASFPSINLQQMLKEVPKRFGDERGAIVHYTILNNHVYR 205

Query: 202 KTHGEHVGFRIFMDAILLSLTRKVKMPDVELFVNLGDWPLEKKKSNSNIHPI--FSWCGS 259
           ++ G++  F++F D ILLSLTRKV +PD+E +VNLGDWPLE +K N    PI   SWCGS
Sbjct: 206 RSLGKYTDFKMFSDEILLSLTRKVLLPDLEFYVNLGDWPLEHRKVNGTPSPIPIISWCGS 265

Query: 260 TDSKDIVMPTYDLTDSVLETMGRVSLDMMSVQANTGPPWESKNSTAVWRGRDSRKERLEL 319
            DS+D+V+PTYD+T S+LE M  V+ D++S+Q NTGP W +K   A +RGRDSR+ERL+L
Sbjct: 266 LDSRDVVLPTYDITHSMLEAMRGVTNDLLSIQGNTGPSWINKTERAFFRGRDSREERLQL 325

Query: 320 VKLSRKHPELIDAAFTNFFFFKHDENLYGPIVKHISFFDFFKHKYQINIDGTVAAYRLPY 379
           V+LS+++P+L+DA  T +FFF+  E   G   K + FFDFFK+KYQ+N+DGTVAAYR PY
Sbjct: 326 VQLSKENPQLLDAGITGYFFFQEKEKELGK-AKLMGFFDFFKYKYQVNVDGTVAAYRYPY 384

Query: 380 LLVGDSVVLKQDSIYYEHFYNELQPWKHYIPVKSNLSDLLEKLKWAKDHDEEAKKIAKAG 439
           L++GDS+VLKQDS YYEHFY  L+PWKHY+P+K NLSDLLEK+KWAK++DEEAKKIAK G
Sbjct: 385 LMLGDSLVLKQDSPYYEHFYMALEPWKHYVPIKRNLSDLLEKVKWAKENDEEAKKIAKEG 444

Query: 440 QEFARNNLMGDDIFCYYFKLFQEYANLQVSEPQIREGMKRVEPQTEDDLFPCTCHRKKTK 499
           Q  AR+ L    ++CYY+++ Q+YA  Q S+P++R+GM+ V PQ ED    C CHRKK  
Sbjct: 445 QLMARDLLQPHRLYCYYYQVLQKYAERQSSKPEVRDGMELV-PQPEDSTAICQCHRKKPS 503

Query: 500 DE 501
            E
Sbjct: 504 RE 505


>gi|31982953 KTEL (Lys-Tyr-Glu-Leu) containing 1 [Homo sapiens]
          Length = 392

 Score =  160 bits (404), Expect = 3e-39
 Identities = 105/341 (30%), Positives = 177/341 (51%), Gaps = 16/341 (4%)

Query: 152 NCPETIAQIQRDLAHFPAVDPEKIAVEIPKRFGQRQSLCHYTLKDNKVYIKTHGEHVGFR 211
           NC      I+ DL  F      K+  E+ +R    +   HY +  N++Y +         
Sbjct: 53  NCSCYHGVIEEDLTPFRGGISRKMMAEVVRR----KLGTHYQITKNRLYRENDCMFPSRC 108

Query: 212 IFMDAILLSLTRKVKMPDVELFVNLGDWPLEKKKSNSNIHPIFSWCGSTDSKDIVMPTYD 271
             ++  +L +  +  +PD+E+ +N+ D+P   K     I P+FS+  +++  DI+ P + 
Sbjct: 109 SGVEHFILEVIGR--LPDMEMVINVRDYPQVPKWMEPAI-PVFSFSKTSEYHDIMYPAWT 165

Query: 272 LTDS------VLET-MGRVSLDMMSVQANTGP-PWESKNSTAVWRGRDSRKERLELVKLS 323
             +       +  T +GR  L    +  +    PW+ KNSTA +RG  +  ER  L+ LS
Sbjct: 166 FWEGGPAVWPIYPTGLGRWDLFREDLVRSAAQWPWKKKNSTAYFRGSRTSPERDPLILLS 225

Query: 324 RKHPELIDAAFTNFFFFKHDENLYG-PIVKHISFFDFFKHKYQINIDGTVAAYRLPYLLV 382
           RK+P+L+DA +T    +K  ++  G P  K +   D  K+KY  N  G  A++R  +L +
Sbjct: 226 RKNPKLVDAEYTKNQAWKSMKDTLGKPAAKDVHLVDHCKYKYLFNFRGVAASFRFKHLFL 285

Query: 383 GDSVVLKQDSIYYEHFYNELQPWKHYIPVKSNLSDLLEKLKWAKDHDEEAKKIAKAGQEF 442
             S+V      + E FY +L+PW HYIPVK++LS++ E L++ K +D+ A++IA+ G +F
Sbjct: 286 CGSLVFHVGDEWLEFFYPQLKPWVHYIPVKTDLSNVQELLQFVKANDDVAQEIAERGSQF 345

Query: 443 ARNNLMGDDIFCYYFKLFQEYANLQVSEPQIREGMKRVEPQ 483
            RN+L  DDI CY+  L  EY+         R+G  ++ P+
Sbjct: 346 IRNHLQMDDITCYWENLLSEYSKFLSYNVTRRKGYDQIIPK 386


>gi|188595687 gamma filamin isoform b [Homo sapiens]
          Length = 2692

 Score = 38.9 bits (89), Expect = 0.011
 Identities = 30/104 (28%), Positives = 53/104 (50%), Gaps = 12/104 (11%)

Query: 25  RQLSPEKSEIWGPGL--KADVVLPARYFYIQAVDTSGNKFTSSPGEKVFQVKVSAPEEQF 82
           +QL+P+K+  +GPG+  + + VL   +F +Q VD       +  GE +  V +  PE   
Sbjct: 271 KQLNPKKAIAYGPGIEPQGNTVLQPAHFTVQTVD-------AGVGEVL--VYIEDPEGHT 321

Query: 83  TRVGVQVLDRKDGSFIVRYRMYASYKNLKVEIKFQGQHVAKSPY 126
               V   + KD ++ V Y    +  + KV + F GQ++ +SP+
Sbjct: 322 EEAKVVPNNDKDRTYAVSYVPKVAGLH-KVTVLFAGQNIERSPF 364



 Score = 31.2 bits (69), Expect = 2.3
 Identities = 32/119 (26%), Positives = 49/119 (41%), Gaps = 22/119 (18%)

Query: 11   FLATVPALAETGGERQLSPEKSEIWGPGLKADVV-LPARYFYIQAVDTSGNKFTSSPGEK 69
            F  TV  L E G        K    G GL+  V  +PA +          + +T   G  
Sbjct: 2269 FQFTVGPLGEGGAH------KVRAGGTGLERGVAGVPAEF----------SIWTREAGAG 2312

Query: 70   VFQVKVSAPEEQFTRVGVQVLDRKDGSFIVRYRMYASYKNLKVEIKFQGQHVAKSPYIL 128
               + V  P    ++  +   DRKDGS  V Y +     + +V IKF  +H+  SP+++
Sbjct: 2313 GLSIAVEGP----SKAEIAFEDRKDGSCGVSY-VVQEPGDYEVSIKFNDEHIPDSPFVV 2366



 Score = 29.6 bits (65), Expect = 6.7
 Identities = 26/89 (29%), Positives = 40/89 (44%), Gaps = 17/89 (19%)

Query: 17  ALAETGGERQLSPE----KSEIWGPGLKADVVLPARYFYIQAVDTSGNKFTSSPGEKVFQ 72
           A+  +  E Q+SPE    K   WGPGL+   V  +  F ++A+ T         G   F 
Sbjct: 555 AIPRSPFEVQVSPEAGVQKVRAWGPGLETGQVGKSADFVVEAIGT-------EVGTLGFS 607

Query: 73  VKVSAPEEQFTRVGVQVLDRKDGSFIVRY 101
           +      E  ++  ++  D+ DGS  VRY
Sbjct: 608 I------EGPSQAKIECDDKGDGSCDVRY 630



 Score = 29.6 bits (65), Expect = 6.7
 Identities = 25/98 (25%), Positives = 39/98 (39%), Gaps = 14/98 (14%)

Query: 29   PEKSEIWGPGLKADVVLPARYFYIQAVDTSGNKFTSSPGEKVFQVKVSAPEEQFTRVGVQ 88
            P +   +GPGL+  +V  A  F ++         T   G     + +  P E      + 
Sbjct: 1350 PTRVRAFGPGLEGGLVNKANRFTVE---------TRGAGTGGLGLAIEGPSE----AKMS 1396

Query: 89   VLDRKDGSFIVRYRMYASYKNLKVEIKFQGQHVAKSPY 126
              D KDGS  V Y  +    +  V I F G+ +  SP+
Sbjct: 1397 CKDNKDGSCTVEYIPFTP-GDYDVNITFGGRPIPGSPF 1433



 Score = 29.6 bits (65), Expect = 6.7
 Identities = 18/60 (30%), Positives = 30/60 (50%), Gaps = 3/60 (5%)

Query: 67   GEKVFQVKVSAPEEQFTRVGVQVLDRKDGSFIVRYRMYASYKNLKVEIKFQGQHVAKSPY 126
            GE      VS P+     + V V++  DG+F + Y      K + + I+F G+H+  SP+
Sbjct: 1674 GEGKVTCTVSTPDG--AELDVDVVENHDGTFDIYYTAPEPGKYV-ITIRFGGEHIPNSPF 1730


>gi|116805322 gamma filamin isoform a [Homo sapiens]
          Length = 2725

 Score = 38.9 bits (89), Expect = 0.011
 Identities = 30/104 (28%), Positives = 53/104 (50%), Gaps = 12/104 (11%)

Query: 25  RQLSPEKSEIWGPGL--KADVVLPARYFYIQAVDTSGNKFTSSPGEKVFQVKVSAPEEQF 82
           +QL+P+K+  +GPG+  + + VL   +F +Q VD       +  GE +  V +  PE   
Sbjct: 271 KQLNPKKAIAYGPGIEPQGNTVLQPAHFTVQTVD-------AGVGEVL--VYIEDPEGHT 321

Query: 83  TRVGVQVLDRKDGSFIVRYRMYASYKNLKVEIKFQGQHVAKSPY 126
               V   + KD ++ V Y    +  + KV + F GQ++ +SP+
Sbjct: 322 EEAKVVPNNDKDRTYAVSYVPKVAGLH-KVTVLFAGQNIERSPF 364



 Score = 31.2 bits (69), Expect = 2.3
 Identities = 32/119 (26%), Positives = 49/119 (41%), Gaps = 22/119 (18%)

Query: 11   FLATVPALAETGGERQLSPEKSEIWGPGLKADVV-LPARYFYIQAVDTSGNKFTSSPGEK 69
            F  TV  L E G        K    G GL+  V  +PA +          + +T   G  
Sbjct: 2302 FQFTVGPLGEGGAH------KVRAGGTGLERGVAGVPAEF----------SIWTREAGAG 2345

Query: 70   VFQVKVSAPEEQFTRVGVQVLDRKDGSFIVRYRMYASYKNLKVEIKFQGQHVAKSPYIL 128
               + V  P    ++  +   DRKDGS  V Y +     + +V IKF  +H+  SP+++
Sbjct: 2346 GLSIAVEGP----SKAEIAFEDRKDGSCGVSY-VVQEPGDYEVSIKFNDEHIPDSPFVV 2399



 Score = 30.4 bits (67), Expect = 3.9
 Identities = 21/71 (29%), Positives = 35/71 (49%), Gaps = 5/71 (7%)

Query: 67   GEKVFQVKVSAPEEQFTRVGVQVLDRKDGSFIVRYRMYASYKNLKVEIKFQGQHVAKSPY 126
            GE      VS P+     + V V++  DG+F + Y      K + + I+F G+H+  SP+
Sbjct: 1674 GEGKVTCTVSTPDG--AELDVDVVENHDGTFDIYYTAPEPGKYV-ITIRFGGEHIPNSPF 1730

Query: 127  --ILKGPVYHE 135
              +   P+ HE
Sbjct: 1731 HVLACDPLPHE 1741



 Score = 29.6 bits (65), Expect = 6.7
 Identities = 26/89 (29%), Positives = 40/89 (44%), Gaps = 17/89 (19%)

Query: 17  ALAETGGERQLSPE----KSEIWGPGLKADVVLPARYFYIQAVDTSGNKFTSSPGEKVFQ 72
           A+  +  E Q+SPE    K   WGPGL+   V  +  F ++A+ T         G   F 
Sbjct: 555 AIPRSPFEVQVSPEAGVQKVRAWGPGLETGQVGKSADFVVEAIGT-------EVGTLGFS 607

Query: 73  VKVSAPEEQFTRVGVQVLDRKDGSFIVRY 101
           +      E  ++  ++  D+ DGS  VRY
Sbjct: 608 I------EGPSQAKIECDDKGDGSCDVRY 630



 Score = 29.6 bits (65), Expect = 6.7
 Identities = 25/98 (25%), Positives = 39/98 (39%), Gaps = 14/98 (14%)

Query: 29   PEKSEIWGPGLKADVVLPARYFYIQAVDTSGNKFTSSPGEKVFQVKVSAPEEQFTRVGVQ 88
            P +   +GPGL+  +V  A  F ++         T   G     + +  P E      + 
Sbjct: 1350 PTRVRAFGPGLEGGLVNKANRFTVE---------TRGAGTGGLGLAIEGPSE----AKMS 1396

Query: 89   VLDRKDGSFIVRYRMYASYKNLKVEIKFQGQHVAKSPY 126
              D KDGS  V Y  +    +  V I F G+ +  SP+
Sbjct: 1397 CKDNKDGSCTVEYIPFTP-GDYDVNITFGGRPIPGSPF 1433


>gi|160420317 filamin A, alpha isoform 2 [Homo sapiens]
          Length = 2647

 Score = 36.2 bits (82), Expect = 0.071
 Identities = 29/103 (28%), Positives = 49/103 (47%), Gaps = 12/103 (11%)

Query: 26  QLSPEKSEIWGPGLK--ADVVLPARYFYIQAVDTSGNKFTSSPGEKVFQVKVSAPEEQFT 83
           +L+P+K+  +GPG++   ++V     F ++         T S G+    V V  P     
Sbjct: 278 KLNPKKARAYGPGIEPTGNMVKKRAEFTVE---------TRSAGQGEVLVYVEDPAGHQE 328

Query: 84  RVGVQVLDRKDGSFIVRYRMYASYKNLKVEIKFQGQHVAKSPY 126
              V   + K+ +F V Y    +  + KV + F GQH+AKSP+
Sbjct: 329 EAKVTANNDKNRTFSVWYVPEVTGTH-KVTVLFAGQHIAKSPF 370



 Score = 34.3 bits (77), Expect = 0.27
 Identities = 32/119 (26%), Positives = 51/119 (42%), Gaps = 22/119 (18%)

Query: 11   FLATVPALAETGGERQLSPEKSEIWGPGL-KADVVLPARYFYIQAVDTSGNKFTSSPGEK 69
            F  TV  L E G        K    GPGL +A+  +PA +          + +T   G  
Sbjct: 2226 FQFTVGPLGEGGAH------KVRAGGPGLERAEAGVPAEF----------SIWTREAGAG 2269

Query: 70   VFQVKVSAPEEQFTRVGVQVLDRKDGSFIVRYRMYASYKNLKVEIKFQGQHVAKSPYIL 128
               + V  P    ++  +   DRKDGS  V Y +     + +V +KF  +H+  SP+++
Sbjct: 2270 GLAIAVEGP----SKAEISFEDRKDGSCGVAY-VVQEPGDYEVSVKFNEEHIPDSPFVV 2323


>gi|116063573 filamin A, alpha isoform 1 [Homo sapiens]
          Length = 2639

 Score = 36.2 bits (82), Expect = 0.071
 Identities = 29/103 (28%), Positives = 49/103 (47%), Gaps = 12/103 (11%)

Query: 26  QLSPEKSEIWGPGLK--ADVVLPARYFYIQAVDTSGNKFTSSPGEKVFQVKVSAPEEQFT 83
           +L+P+K+  +GPG++   ++V     F ++         T S G+    V V  P     
Sbjct: 278 KLNPKKARAYGPGIEPTGNMVKKRAEFTVE---------TRSAGQGEVLVYVEDPAGHQE 328

Query: 84  RVGVQVLDRKDGSFIVRYRMYASYKNLKVEIKFQGQHVAKSPY 126
              V   + K+ +F V Y    +  + KV + F GQH+AKSP+
Sbjct: 329 EAKVTANNDKNRTFSVWYVPEVTGTH-KVTVLFAGQHIAKSPF 370



 Score = 34.3 bits (77), Expect = 0.27
 Identities = 32/119 (26%), Positives = 51/119 (42%), Gaps = 22/119 (18%)

Query: 11   FLATVPALAETGGERQLSPEKSEIWGPGL-KADVVLPARYFYIQAVDTSGNKFTSSPGEK 69
            F  TV  L E G        K    GPGL +A+  +PA +          + +T   G  
Sbjct: 2218 FQFTVGPLGEGGAH------KVRAGGPGLERAEAGVPAEF----------SIWTREAGAG 2261

Query: 70   VFQVKVSAPEEQFTRVGVQVLDRKDGSFIVRYRMYASYKNLKVEIKFQGQHVAKSPYIL 128
               + V  P    ++  +   DRKDGS  V Y +     + +V +KF  +H+  SP+++
Sbjct: 2262 GLAIAVEGP----SKAEISFEDRKDGSCGVAY-VVQEPGDYEVSVKFNEEHIPDSPFVV 2315


>gi|105990514 filamin B, beta (actin binding protein 278) [Homo
           sapiens]
          Length = 2602

 Score = 33.1 bits (74), Expect = 0.60
 Identities = 30/104 (28%), Positives = 49/104 (47%), Gaps = 14/104 (13%)

Query: 26  QLSPEKSEIWGPGLKAD---VVLPARYFYIQAVDTSGNKFTSSPGEKVFQVKVSAPEEQF 82
           +L+P+K+  +G G++     V  PA++     VDT       S G+    V V  PE   
Sbjct: 251 KLNPKKARAYGRGIEPTGNMVKQPAKF----TVDTI------SAGQGDVMVFVEDPEGNK 300

Query: 83  TRVGVQVLDRKDGSFIVRYRMYASYKNLKVEIKFQGQHVAKSPY 126
               V     K+ ++ V Y    +  + KV + F GQH++KSP+
Sbjct: 301 EEAQVTPDSDKNKTYSVEYLPKVTGLH-KVTVLFAGQHISKSPF 343



 Score = 32.7 bits (73), Expect = 0.79
 Identities = 32/119 (26%), Positives = 50/119 (42%), Gaps = 22/119 (18%)

Query: 11   FLATVPALAETGGERQLSPEKSEIWGPGL-KADVVLPARYFYIQAVDTSGNKFTSSPGEK 69
            F  TV  L E G        K    GPGL + +  +PA +          + +T   G  
Sbjct: 2181 FQFTVGPLGEGGAH------KVRAGGPGLERGEAGVPAEF----------SIWTREAGAG 2224

Query: 70   VFQVKVSAPEEQFTRVGVQVLDRKDGSFIVRYRMYASYKNLKVEIKFQGQHVAKSPYIL 128
               + V  P    ++  +   D K+GS  V Y +     N +V IKF  +H+ +SPY++
Sbjct: 2225 GLSIAVEGP----SKAEITFDDHKNGSCGVSY-IAQEPGNYEVSIKFNDEHIPESPYLV 2278


>gi|88702793 slit-like 2 [Homo sapiens]
          Length = 673

 Score = 30.4 bits (67), Expect = 3.9
 Identities = 14/44 (31%), Positives = 23/44 (52%), Gaps = 2/44 (4%)

Query: 136 NCDCPLQDSAAWLREMNCPETIAQIQRDLAHFPAVDPEKIAVEI 179
           NC CPL     W+RE +   T+A  +    HFP  +  ++ +E+
Sbjct: 301 NCVCPLSWFGPWVRESHV--TLASPEETRCHFPPKNAGRLLLEL 342


>gi|226342962 synaptotagmin XIV isoform 2 [Homo sapiens]
          Length = 600

 Score = 30.0 bits (66), Expect = 5.1
 Identities = 21/76 (27%), Positives = 33/76 (43%), Gaps = 14/76 (18%)

Query: 95  GSFIVRYRMYASYKNLKVEI---------KFQGQHVAKSPYILKGPVYHENCDCPLQDSA 145
           G++ VR+R+Y  ++  K +I         K   Q     P IL+    H  CD  +  S 
Sbjct: 384 GNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKMSLPVILEPSYNHSGCDSQMSVS- 442

Query: 146 AWLREMNCPETIAQIQ 161
               EM+C E+ +  Q
Sbjct: 443 ----EMSCSESTSSCQ 454


>gi|226342957 synaptotagmin XIV isoform 3 [Homo sapiens]
          Length = 574

 Score = 30.0 bits (66), Expect = 5.1
 Identities = 21/76 (27%), Positives = 33/76 (43%), Gaps = 14/76 (18%)

Query: 95  GSFIVRYRMYASYKNLKVEI---------KFQGQHVAKSPYILKGPVYHENCDCPLQDSA 145
           G++ VR+R+Y  ++  K +I         K   Q     P IL+    H  CD  +  S 
Sbjct: 339 GNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKMSLPVILEPSYNHSGCDSQMSVS- 397

Query: 146 AWLREMNCPETIAQIQ 161
               EM+C E+ +  Q
Sbjct: 398 ----EMSCSESTSSCQ 409


>gi|226342955 synaptotagmin XIV isoform 1 [Homo sapiens]
          Length = 619

 Score = 30.0 bits (66), Expect = 5.1
 Identities = 21/76 (27%), Positives = 33/76 (43%), Gaps = 14/76 (18%)

Query: 95  GSFIVRYRMYASYKNLKVEI---------KFQGQHVAKSPYILKGPVYHENCDCPLQDSA 145
           G++ VR+R+Y  ++  K +I         K   Q     P IL+    H  CD  +  S 
Sbjct: 384 GNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKMSLPVILEPSYNHSGCDSQMSVS- 442

Query: 146 AWLREMNCPETIAQIQ 161
               EM+C E+ +  Q
Sbjct: 443 ----EMSCSESTSSCQ 454


>gi|144226225 synaptotagmin XIV isoform 4 [Homo sapiens]
          Length = 555

 Score = 30.0 bits (66), Expect = 5.1
 Identities = 21/76 (27%), Positives = 33/76 (43%), Gaps = 14/76 (18%)

Query: 95  GSFIVRYRMYASYKNLKVEI---------KFQGQHVAKSPYILKGPVYHENCDCPLQDSA 145
           G++ VR+R+Y  ++  K +I         K   Q     P IL+    H  CD  +  S 
Sbjct: 339 GNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKMSLPVILEPSYNHSGCDSQMSVS- 397

Query: 146 AWLREMNCPETIAQIQ 161
               EM+C E+ +  Q
Sbjct: 398 ----EMSCSESTSSCQ 409


>gi|14149981 transmembrane protein 117 [Homo sapiens]
          Length = 514

 Score = 29.3 bits (64), Expect = 8.7
 Identities = 38/130 (29%), Positives = 54/130 (41%), Gaps = 15/130 (11%)

Query: 343 DENLYGPIVKH----ISFFD-FFKHKYQINIDGTVAAYRLPYL-LVGDSVVLKQDSIYYE 396
           D NL G    H    I FF   FK +Y+I+I G    Y + +L L+ D  + K    Y  
Sbjct: 268 DVNLPGLHTPHMQFKIPFFQKIFKEEYRIHITGKWFNYGIIFLVLILDLNMWKNQIFYKP 327

Query: 397 HFYNE-LQPWKHYIPVK--SNLSDL-LEKLKW---AKDHDEEAKKIAKAGQEFARNNLMG 449
           H Y + + P +    VK   +L DL   KL W   +   +    K    G  F  +  +G
Sbjct: 328 HEYGQYIGPGQKIYTVKDSESLKDLNRTKLSWEWRSNHTNPRTNKTYVEGDMFLHSRFIG 387

Query: 450 D--DIFCYYF 457
              D+ C  F
Sbjct: 388 ASLDVKCLAF 397


>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
           [Homo sapiens]
          Length = 918

 Score = 29.3 bits (64), Expect = 8.7
 Identities = 15/57 (26%), Positives = 27/57 (47%), Gaps = 1/57 (1%)

Query: 252 PIFSWCGSTDSKDIVMPTYDLTDSVLETMGRV-SLDMMSVQANTGPPWESKNSTAVW 307
           PI +W   T     ++  Y    ++LE  G +  LD+  +   + P +  + S+AVW
Sbjct: 841 PIPTWARGTPLSQAIIHQYYHPPNLLELFGTILPLDLEDIFKKSKPRYHKRTSSAVW 897


>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
           [Homo sapiens]
          Length = 914

 Score = 29.3 bits (64), Expect = 8.7
 Identities = 15/57 (26%), Positives = 27/57 (47%), Gaps = 1/57 (1%)

Query: 252 PIFSWCGSTDSKDIVMPTYDLTDSVLETMGRV-SLDMMSVQANTGPPWESKNSTAVW 307
           PI +W   T     ++  Y    ++LE  G +  LD+  +   + P +  + S+AVW
Sbjct: 837 PIPTWARGTPLSQAIIHQYYHPPNLLELFGTILPLDLEDIFKKSKPRYHKRTSSAVW 893


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.137    0.421 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,375,776
Number of Sequences: 37866
Number of extensions: 849148
Number of successful extensions: 1846
Number of sequences better than 10.0: 16
Number of HSP's better than 10.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 13
Number of HSP's that attempted gapping in prelim test: 1787
Number of HSP's gapped (non-prelim): 59
length of query: 502
length of database: 18,247,518
effective HSP length: 107
effective length of query: 395
effective length of database: 14,195,856
effective search space: 5607363120
effective search space used: 5607363120
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.