Guide to the Human Genome
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Search of human proteins with 170016081

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|170016081 XRP2 protein [Homo sapiens]
         (350 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|170016081 XRP2 protein [Homo sapiens]                              720   0.0  
gi|4507373 beta-tubulin cofactor C [Homo sapiens]                     104   1e-22
gi|197313654 TBCC domain containing 1 [Homo sapiens]                   62   8e-10
gi|8922517 TBCC domain containing 1 [Homo sapiens]                     62   8e-10
gi|188497758 ubiquitin associated protein 2-like isoform a [Homo...    33   0.50 
gi|188497756 ubiquitin associated protein 2-like isoform b [Homo...    33   0.50 
gi|33188459 B-Raf [Homo sapiens]                                       32   0.65 
gi|12711676 UPF3 regulator of nonsense transcripts homolog A iso...    32   0.85 
gi|18375525 UPF3 regulator of nonsense transcripts homolog A iso...    32   0.85 
gi|219521928 DIS3 mitotic control homolog (S. cerevisiae)-like i...    30   2.5  
gi|33356128 NMDA receptor regulated 1-like protein isoform 1 [Ho...    30   2.5  
gi|38569398 integrin, alpha 10 precursor [Homo sapiens]                30   4.2  
gi|186700629 calcium/calmodulin-dependent serine protein kinase ...    29   5.5  
gi|186700627 calcium/calmodulin-dependent serine protein kinase ...    29   5.5  
gi|186972120 calcium/calmodulin-dependent serine protein kinase ...    29   5.5  
gi|27477095 nuclear receptor binding SET domain protein 1 isofor...    29   5.5  
gi|19923586 nuclear receptor binding SET domain protein 1 isofor...    29   5.5  
gi|209870052 transmembrane protein 132C [Homo sapiens]                 29   5.5  
gi|22758136 MAP7 domain containing 2 [Homo sapiens]                    29   5.5  
gi|31377566 ring finger protein 168 [Homo sapiens]                     29   7.2  
gi|55743151 WD repeat domain 19 [Homo sapiens]                         28   9.4  
gi|93204885 chromosome 1 open reading frame 14 [Homo sapiens]          28   9.4  

>gi|170016081 XRP2 protein [Homo sapiens]
          Length = 350

 Score =  720 bits (1859), Expect = 0.0
 Identities = 350/350 (100%), Positives = 350/350 (100%)

Query: 1   MGCFFSKRRKADKESRPENEEERPKQYSWDQREKVDPKDYMFSGLKDETVGRLPGTVAGQ 60
           MGCFFSKRRKADKESRPENEEERPKQYSWDQREKVDPKDYMFSGLKDETVGRLPGTVAGQ
Sbjct: 1   MGCFFSKRRKADKESRPENEEERPKQYSWDQREKVDPKDYMFSGLKDETVGRLPGTVAGQ 60

Query: 61  QFLIQDCENCNIYIFDHSATVTIDDCTNCIIFLGPVKGSVFFRNCRDCKCTLACQQFRVR 120
           QFLIQDCENCNIYIFDHSATVTIDDCTNCIIFLGPVKGSVFFRNCRDCKCTLACQQFRVR
Sbjct: 61  QFLIQDCENCNIYIFDHSATVTIDDCTNCIIFLGPVKGSVFFRNCRDCKCTLACQQFRVR 120

Query: 121 DCRKLEVFLCCATQPIIESSSNIKFGCFQWYYPELAFQFKDAGLSIFNNTWSNIHDFTPV 180
           DCRKLEVFLCCATQPIIESSSNIKFGCFQWYYPELAFQFKDAGLSIFNNTWSNIHDFTPV
Sbjct: 121 DCRKLEVFLCCATQPIIESSSNIKFGCFQWYYPELAFQFKDAGLSIFNNTWSNIHDFTPV 180

Query: 181 SGELNWSLLPEDAVVQDYVPIPTTEELKAVRVSTEANRSIVPISRGQRQKSSDESCLVVL 240
           SGELNWSLLPEDAVVQDYVPIPTTEELKAVRVSTEANRSIVPISRGQRQKSSDESCLVVL
Sbjct: 181 SGELNWSLLPEDAVVQDYVPIPTTEELKAVRVSTEANRSIVPISRGQRQKSSDESCLVVL 240

Query: 241 FAGDYTIANARKLIDEMVGKGFFLVQTKEVSMKAEDAQRVFREKAPDFLPLLNKGPVIAL 300
           FAGDYTIANARKLIDEMVGKGFFLVQTKEVSMKAEDAQRVFREKAPDFLPLLNKGPVIAL
Sbjct: 241 FAGDYTIANARKLIDEMVGKGFFLVQTKEVSMKAEDAQRVFREKAPDFLPLLNKGPVIAL 300

Query: 301 EFNGDGAVEVCQLIVNEIFNGTKMFVSESKETASGDVDSFYNFADIQMGI 350
           EFNGDGAVEVCQLIVNEIFNGTKMFVSESKETASGDVDSFYNFADIQMGI
Sbjct: 301 EFNGDGAVEVCQLIVNEIFNGTKMFVSESKETASGDVDSFYNFADIQMGI 350


>gi|4507373 beta-tubulin cofactor C [Homo sapiens]
          Length = 346

 Score =  104 bits (260), Expect = 1e-22
 Identities = 46/154 (29%), Positives = 84/154 (54%), Gaps = 3/154 (1%)

Query: 42  FSGLKDETVGRLPGTVAGQQFLIQDCENCNIYIFDHSATVTIDDCTNCIIFLGPVKGSVF 101
           FS L+ + + +    +  +  L+ +  NC + ++ +  T+ +    +C +  GPV  SVF
Sbjct: 186 FSNLESQVLEKRASELHQRDVLLTELSNCTVRLYGNPNTLRLTKAHSCKLLCGPVSTSVF 245

Query: 102 FRNCRDCKCTLACQQFRVRDCRKLEVFLCCATQPIIESSSNIKFGCFQWYYPELAFQFKD 161
             +C DC   +ACQQ R+   +   +FL   ++ I+E  S I+F  + W YPE+   F+ 
Sbjct: 246 LEDCSDCVLAVACQQLRIHSTKDTRIFLQVTSRAIVEDCSGIQFAPYTWSYPEIDKDFES 305

Query: 162 AGLSIFNNTWSNIHDFTPVSGEL---NWSLLPED 192
           +GL    N W+++ DF  ++ ++   NWS+LPE+
Sbjct: 306 SGLDRSKNNWNDVDDFNWLARDMASPNWSILPEE 339


>gi|197313654 TBCC domain containing 1 [Homo sapiens]
          Length = 557

 Score = 62.0 bits (149), Expect = 8e-10
 Identities = 36/134 (26%), Positives = 58/134 (43%), Gaps = 1/134 (0%)

Query: 41  MFSGLKDETVGRLPGTVAGQQFLIQDCENCNIYIFDHSATVTIDDCTNCIIFLGPVKGSV 100
           + S +  +T+ +   T+AG    I  C    IY+     +VTI+ C N I  LGPV  ++
Sbjct: 311 VMSQVYKQTLAKSSDTLAGAHVKIHRCNESFIYLLSPLRSVTIEKCRNSIFVLGPVGTTL 370

Query: 101 FFRNCRDCKCTLACQQFRVRDCRKLEVFLCCATQPIIES-SSNIKFGCFQWYYPELAFQF 159
              +C + K    C +  +         +   T+P+I S +  + F  F  +YP L    
Sbjct: 371 HLHSCDNVKVIAVCHRLSISSTTGCIFHVLTPTRPLILSGNQTVTFAPFHTHYPMLEDHM 430

Query: 160 KDAGLSIFNNTWSN 173
              GL+   N W N
Sbjct: 431 ARTGLATVPNYWDN 444


>gi|8922517 TBCC domain containing 1 [Homo sapiens]
          Length = 557

 Score = 62.0 bits (149), Expect = 8e-10
 Identities = 36/134 (26%), Positives = 58/134 (43%), Gaps = 1/134 (0%)

Query: 41  MFSGLKDETVGRLPGTVAGQQFLIQDCENCNIYIFDHSATVTIDDCTNCIIFLGPVKGSV 100
           + S +  +T+ +   T+AG    I  C    IY+     +VTI+ C N I  LGPV  ++
Sbjct: 311 VMSQVYKQTLAKSSDTLAGAHVKIHRCNESFIYLLSPLRSVTIEKCRNSIFVLGPVGTTL 370

Query: 101 FFRNCRDCKCTLACQQFRVRDCRKLEVFLCCATQPIIES-SSNIKFGCFQWYYPELAFQF 159
              +C + K    C +  +         +   T+P+I S +  + F  F  +YP L    
Sbjct: 371 HLHSCDNVKVIAVCHRLSISSTTGCIFHVLTPTRPLILSGNQTVTFAPFHTHYPMLEDHM 430

Query: 160 KDAGLSIFNNTWSN 173
              GL+   N W N
Sbjct: 431 ARTGLATVPNYWDN 444


>gi|188497758 ubiquitin associated protein 2-like isoform a [Homo
           sapiens]
          Length = 1087

 Score = 32.7 bits (73), Expect = 0.50
 Identities = 17/55 (30%), Positives = 26/55 (47%), Gaps = 5/55 (9%)

Query: 169 NTWSNIHDFTPVSGELNWSLLPEDAVVQDYVPIPTTEELKAVRVSTEANRSIVPI 223
           NTW+N   F P  G   W    E+   +D+      E+L   ++ T +N S VP+
Sbjct: 220 NTWNNTGHFEPDDGTSAWRTATEEWGTEDW-----NEDLSETKIFTASNVSSVPL 269


>gi|188497756 ubiquitin associated protein 2-like isoform b [Homo
           sapiens]
          Length = 983

 Score = 32.7 bits (73), Expect = 0.50
 Identities = 17/55 (30%), Positives = 26/55 (47%), Gaps = 5/55 (9%)

Query: 169 NTWSNIHDFTPVSGELNWSLLPEDAVVQDYVPIPTTEELKAVRVSTEANRSIVPI 223
           NTW+N   F P  G   W    E+   +D+      E+L   ++ T +N S VP+
Sbjct: 220 NTWNNTGHFEPDDGTSAWRTATEEWGTEDW-----NEDLSETKIFTASNVSSVPL 269


>gi|33188459 B-Raf [Homo sapiens]
          Length = 766

 Score = 32.3 bits (72), Expect = 0.65
 Identities = 16/49 (32%), Positives = 25/49 (51%), Gaps = 1/49 (2%)

Query: 152 YPELAFQFKDAGLSIFNNTWSNIHDFTPVSGELNWSLLPEDAVVQDYVP 200
           + +L  +  D GL+   + WS  H F  +SG + W + PE   +QD  P
Sbjct: 585 HEDLTVKIGDFGLATVKSRWSGSHQFEQLSGSILW-MAPEVIRMQDKNP 632


>gi|12711676 UPF3 regulator of nonsense transcripts homolog A
           isoform hUpf3p [Homo sapiens]
          Length = 476

 Score = 32.0 bits (71), Expect = 0.85
 Identities = 17/50 (34%), Positives = 26/50 (52%)

Query: 7   KRRKADKESRPENEEERPKQYSWDQREKVDPKDYMFSGLKDETVGRLPGT 56
           K+R  ++E R   EEER K+   D+++K+  K+     LK    G  P T
Sbjct: 246 KKRLREEEKRRRREEERCKKKETDKQKKIAEKEVRIKLLKKPEKGEEPTT 295


>gi|18375525 UPF3 regulator of nonsense transcripts homolog A
           isoform hUpf3pdelta [Homo sapiens]
          Length = 443

 Score = 32.0 bits (71), Expect = 0.85
 Identities = 17/50 (34%), Positives = 26/50 (52%)

Query: 7   KRRKADKESRPENEEERPKQYSWDQREKVDPKDYMFSGLKDETVGRLPGT 56
           K+R  ++E R   EEER K+   D+++K+  K+     LK    G  P T
Sbjct: 213 KKRLREEEKRRRREEERCKKKETDKQKKIAEKEVRIKLLKKPEKGEEPTT 262


>gi|219521928 DIS3 mitotic control homolog (S. cerevisiae)-like
           isoform 1 [Homo sapiens]
          Length = 1054

 Score = 30.4 bits (67), Expect = 2.5
 Identities = 22/77 (28%), Positives = 38/77 (49%), Gaps = 7/77 (9%)

Query: 175 HDFTPVSGELNWSLLPEDAVVQDYVPIPTTEELKAVRVSTEANRSIVPISRGQRQKSSDE 234
           HD   +S ++   ++P+  VVQDY+ I    ELK + +  +     V   RG+RQ +   
Sbjct: 46  HDGKLLSSDVTHYVIPDWKVVQDYLEILEFPELKGI-IFMQTACQAVQHQRGRRQYNKLR 104

Query: 235 SCL------VVLFAGDY 245
           + L       +LFA ++
Sbjct: 105 NLLKDARHDCILFANEF 121


>gi|33356128 NMDA receptor regulated 1-like protein isoform 1 [Homo
           sapiens]
          Length = 864

 Score = 30.4 bits (67), Expect = 2.5
 Identities = 18/48 (37%), Positives = 31/48 (64%), Gaps = 4/48 (8%)

Query: 6   SKRRKADKESRPENEE---ERPKQYSWDQREKVDPKDYMFSGLKDETV 50
           SK+R+A K+++ E E    ER +Q   +Q++K D ++   SGLK+E +
Sbjct: 597 SKQRRAQKKAKLEEERKHAERERQQK-NQKKKRDEEEEEASGLKEELI 643


>gi|38569398 integrin, alpha 10 precursor [Homo sapiens]
          Length = 1167

 Score = 29.6 bits (65), Expect = 4.2
 Identities = 18/47 (38%), Positives = 24/47 (51%), Gaps = 3/47 (6%)

Query: 271 SMKAEDAQRVFREKAPDFLPLLNKGPVIALEFNGDGAVEVCQLIVNE 317
           SM     +R+F   AP F    ++G VIA +   DGAV V Q +  E
Sbjct: 437 SMLLRGGRRLFLSGAPRFR---HRGKVIAFQLKKDGAVRVAQSLQGE 480


>gi|186700629 calcium/calmodulin-dependent serine protein kinase
           isoform 3 [Homo sapiens]
          Length = 897

 Score = 29.3 bits (64), Expect = 5.5
 Identities = 20/65 (30%), Positives = 33/65 (50%), Gaps = 8/65 (12%)

Query: 274 AEDAQRVFREKAPDFLPLLNKGPVIALEFNGDGAVEVCQLIVNEIFNGTKMFVSESKETA 333
           A++ +R+  +  P F+ LL    V+A E   D A+ V     +   NG      +S E+A
Sbjct: 419 AKELKRILTQ--PHFMALLQTHDVVAHEVYSDEALRVTPPPTSPYLNG------DSPESA 470

Query: 334 SGDVD 338
           +GD+D
Sbjct: 471 NGDMD 475


>gi|186700627 calcium/calmodulin-dependent serine protein kinase
           isoform 2 [Homo sapiens]
          Length = 898

 Score = 29.3 bits (64), Expect = 5.5
 Identities = 20/65 (30%), Positives = 33/65 (50%), Gaps = 8/65 (12%)

Query: 274 AEDAQRVFREKAPDFLPLLNKGPVIALEFNGDGAVEVCQLIVNEIFNGTKMFVSESKETA 333
           A++ +R+  +  P F+ LL    V+A E   D A+ V     +   NG      +S E+A
Sbjct: 425 AKELKRILTQ--PHFMALLQTHDVVAHEVYSDEALRVTPPPTSPYLNG------DSPESA 476

Query: 334 SGDVD 338
           +GD+D
Sbjct: 477 NGDMD 481


>gi|186972120 calcium/calmodulin-dependent serine protein kinase
           isoform 1 [Homo sapiens]
          Length = 921

 Score = 29.3 bits (64), Expect = 5.5
 Identities = 20/65 (30%), Positives = 33/65 (50%), Gaps = 8/65 (12%)

Query: 274 AEDAQRVFREKAPDFLPLLNKGPVIALEFNGDGAVEVCQLIVNEIFNGTKMFVSESKETA 333
           A++ +R+  +  P F+ LL    V+A E   D A+ V     +   NG      +S E+A
Sbjct: 425 AKELKRILTQ--PHFMALLQTHDVVAHEVYSDEALRVTPPPTSPYLNG------DSPESA 476

Query: 334 SGDVD 338
           +GD+D
Sbjct: 477 NGDMD 481


>gi|27477095 nuclear receptor binding SET domain protein 1 isoform a
           [Homo sapiens]
          Length = 2427

 Score = 29.3 bits (64), Expect = 5.5
 Identities = 24/101 (23%), Positives = 37/101 (36%), Gaps = 8/101 (7%)

Query: 5   FSKRRKADKESRPENEEERPKQYSWDQREKVDPKDYMFSGLKDETVGRLPGTVAGQQFLI 64
           F     AD++ +P  +    K     +R  V      F   KDE  G++P  + G  F+ 
Sbjct: 212 FDSEHSADEKEKPCAKSRARKSSDNPKRTSVKKGHIQFEAHKDERRGKIPENL-GLNFIS 270

Query: 65  QDCENCNIYIFDHSATVTIDDCTNCIIFLGPVKGSVFFRNC 105
            D       I D  A+  +    N +       GS  F +C
Sbjct: 271 GD-------ISDTQASNELSRIANSLTGSNTAPGSFLFSSC 304


>gi|19923586 nuclear receptor binding SET domain protein 1 isoform b
           [Homo sapiens]
          Length = 2696

 Score = 29.3 bits (64), Expect = 5.5
 Identities = 24/101 (23%), Positives = 37/101 (36%), Gaps = 8/101 (7%)

Query: 5   FSKRRKADKESRPENEEERPKQYSWDQREKVDPKDYMFSGLKDETVGRLPGTVAGQQFLI 64
           F     AD++ +P  +    K     +R  V      F   KDE  G++P  + G  F+ 
Sbjct: 481 FDSEHSADEKEKPCAKSRARKSSDNPKRTSVKKGHIQFEAHKDERRGKIPENL-GLNFIS 539

Query: 65  QDCENCNIYIFDHSATVTIDDCTNCIIFLGPVKGSVFFRNC 105
            D       I D  A+  +    N +       GS  F +C
Sbjct: 540 GD-------ISDTQASNELSRIANSLTGSNTAPGSFLFSSC 573


>gi|209870052 transmembrane protein 132C [Homo sapiens]
          Length = 996

 Score = 29.3 bits (64), Expect = 5.5
 Identities = 15/46 (32%), Positives = 24/46 (52%)

Query: 212 VSTEANRSIVPISRGQRQKSSDESCLVVLFAGDYTIANARKLIDEM 257
           VS E N +++ IS     KS+DE  + V    DY   N +++  +M
Sbjct: 345 VSVEENSAVMDISESVECKSTDEDVIKVSERCDYIFVNGKEIKGKM 390


>gi|22758136 MAP7 domain containing 2 [Homo sapiens]
          Length = 732

 Score = 29.3 bits (64), Expect = 5.5
 Identities = 24/86 (27%), Positives = 40/86 (46%), Gaps = 6/86 (6%)

Query: 254 IDEMVGKGFFLVQTKEVSMKAEDAQRVFREKA---PDFLPLLNKGPVIALEFNGDGAVEV 310
           +D + GK   L  + E  +++ D   V +E+    P+F P+    P ++L+ NG G    
Sbjct: 627 LDALDGKSNSLDDSTE-EVQSMDVSPVSKEELISIPEFSPVSEMIPGVSLDQNGTGNARA 685

Query: 311 CQLIVNEIFNGTKMFVSESKETASGD 336
            Q +++  F G   F   S E  S D
Sbjct: 686 LQDLLD--FTGPPTFPKRSSENLSLD 709


>gi|31377566 ring finger protein 168 [Homo sapiens]
          Length = 571

 Score = 28.9 bits (63), Expect = 7.2
 Identities = 18/51 (35%), Positives = 27/51 (52%), Gaps = 4/51 (7%)

Query: 3   CFFSKRRKADKESRPENEEERPKQYSWDQREKVDPKDYMFSGLKDETVGRL 53
           CF +KRRK   ES P+ EE    + ++ Q+  +D +  +F   K E   RL
Sbjct: 402 CFSAKRRKVSPESSPDQEE---TEINFTQK-LIDLEHLLFERHKQEEQDRL 448


>gi|55743151 WD repeat domain 19 [Homo sapiens]
          Length = 1342

 Score = 28.5 bits (62), Expect = 9.4
 Identities = 33/149 (22%), Positives = 58/149 (38%), Gaps = 18/149 (12%)

Query: 209 AVRVSTEANRSIVPISRGQRQKSSDESCL---VVLFAGDYTIANARKLIDEMVGKGFFLV 265
           A+RV        + +S  Q +   D + L   + +F  DY +A    L           +
Sbjct: 694 AIRVYRRIGNVGIVMSLEQIKGIEDYNLLAGHLAMFTNDYNLAQDLYLASSCP---IAAL 750

Query: 266 QTKEVSMKAEDAQRVFREKAPDFLPLLNKGPVIALEFNGDGAVEVCQLIVNEIFNGTKMF 325
           + +      + A ++ +  APD +P ++K   I LEF GD         VN + +  K  
Sbjct: 751 EMRRDLQHWDSALQLAKHLAPDQIPFISKEYAIQLEFAGD--------YVNALAHYEKGI 802

Query: 326 VSESKE----TASGDVDSFYNFADIQMGI 350
             ++KE      +G         DI+ G+
Sbjct: 803 TGDNKEHDEACLAGVAQMSIRMGDIRRGV 831


>gi|93204885 chromosome 1 open reading frame 14 [Homo sapiens]
          Length = 653

 Score = 28.5 bits (62), Expect = 9.4
 Identities = 26/108 (24%), Positives = 52/108 (48%), Gaps = 13/108 (12%)

Query: 238 VVLFAGDYTIANARKLIDEMVGKGFFLVQTKEVSMKAEDAQRVFREKAPD-----FLPLL 292
           V++F G+Y  AN   L D+++ KG  + + +E+ + +E ++  F     D      L L+
Sbjct: 423 VIIFPGEYQAANLALLTDDIIIKG--VGKREEIMITSEPSRDSFVVSKADNVKLMHLSLI 480

Query: 293 NKGPV--IALEFNGDGAVEVCQLIVNE----IFNGTKMFVSESKETAS 334
            +G V  I +  +G   +E C L        +  G  + +++S+ T +
Sbjct: 481 QQGTVDGIVVVESGHMTLENCILKCEGTGVCVLTGAALTITDSEITGA 528


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.137    0.421 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,399,587
Number of Sequences: 37866
Number of extensions: 602091
Number of successful extensions: 1721
Number of sequences better than 10.0: 22
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 14
Number of HSP's that attempted gapping in prelim test: 1703
Number of HSP's gapped (non-prelim): 24
length of query: 350
length of database: 18,247,518
effective HSP length: 103
effective length of query: 247
effective length of database: 14,347,320
effective search space: 3543788040
effective search space used: 3543788040
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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