Guide to the Human Genome
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Search of human proteins with 169881239

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|169881239 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
[Homo sapiens]
         (660 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|169881239 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked ...  1349   0.0  
gi|13514809 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked [...  1349   0.0  
gi|87196351 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3 [Homo...  1241   0.0  
gi|209862869 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 3 ...   446   e-125
gi|13518015 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 1 [...   446   e-125
gi|216548263 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 2 ...   446   e-125
gi|4758138 DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 [Homo sapiens]    328   7e-90
gi|38201710 DEAD box polypeptide 17 isoform 1 [Homo sapiens]          325   6e-89
gi|148613856 DEAD box polypeptide 17 isoform 3 [Homo sapiens]         325   8e-89
gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapi...   289   6e-78
gi|21071032 DEAD-box protein abstrakt [Homo sapiens]                  288   1e-77
gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo sapi...   277   3e-74
gi|222352149 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 [Homo sap...   272   6e-73
gi|45446747 DEAD box polypeptide 42 protein [Homo sapiens]            268   9e-72
gi|45446743 DEAD box polypeptide 42 protein [Homo sapiens]            268   9e-72
gi|55749865 DEAD (Asp-Glu-Ala-Asp) box polypeptide 53 [Homo sapi...   245   1e-64
gi|188035877 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 [Homo sap...   230   3e-60
gi|224593278 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 [Homo sap...   211   1e-54
gi|20149629 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 1 ...   210   3e-54
gi|7661920 eukaryotic translation initiation factor 4A, isoform ...   209   9e-54
gi|38569503 ATP-dependent RNA helicase ROK1 isoform b [Homo sapi...   206   6e-53
gi|38569505 ATP-dependent RNA helicase ROK1 isoform a [Homo sapi...   206   6e-53
gi|4503529 eukaryotic translation initiation factor 4A isoform 1...   202   8e-52
gi|83700235 eukaryotic translation initiation factor 4A2 [Homo s...   202   1e-51
gi|50659095 DEAD (Asp-Glu-Ala-Asp) box polypeptide 21 [Homo sapi...   187   2e-47
gi|13129006 nucleolar protein GU2 [Homo sapiens]                      182   1e-45
gi|164664518 DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 [Homo sapi...   180   3e-45
gi|51094101 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 2 ...   180   4e-45
gi|164419743 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 1...   180   4e-45
gi|31542656 DEAD (Asp-Glu-Ala-Asp) box polypeptide 49 [Homo sapi...   178   1e-44

>gi|169881239 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
           [Homo sapiens]
          Length = 660

 Score = 1349 bits (3492), Expect = 0.0
 Identities = 660/660 (100%), Positives = 660/660 (100%)

Query: 1   MSHVVVKNDPELDQQLANLDLNSEKQSGGASTASKGRYIPPHLRNREASKGFHDKDSSGW 60
           MSHVVVKNDPELDQQLANLDLNSEKQSGGASTASKGRYIPPHLRNREASKGFHDKDSSGW
Sbjct: 1   MSHVVVKNDPELDQQLANLDLNSEKQSGGASTASKGRYIPPHLRNREASKGFHDKDSSGW 60

Query: 61  SCSKDKDAYSSFGSRDSRGKPGYFSERGSGSRGRFDDRGRSDYDGIGNRERPGFGRFERS 120
           SCSKDKDAYSSFGSRDSRGKPGYFSERGSGSRGRFDDRGRSDYDGIGNRERPGFGRFERS
Sbjct: 61  SCSKDKDAYSSFGSRDSRGKPGYFSERGSGSRGRFDDRGRSDYDGIGNRERPGFGRFERS 120

Query: 121 GHSRWCDKSVEDDWSKPLPPSERLEQELFSGGNTGINFEKYDDIPVEATGSNCPPHIENF 180
           GHSRWCDKSVEDDWSKPLPPSERLEQELFSGGNTGINFEKYDDIPVEATGSNCPPHIENF
Sbjct: 121 GHSRWCDKSVEDDWSKPLPPSERLEQELFSGGNTGINFEKYDDIPVEATGSNCPPHIENF 180

Query: 181 SDIDMGEIIMGNIELTRYTRPTPVQKHAIPIIKGKRDLMACAQTGSGKTAAFLLPILSQI 240
           SDIDMGEIIMGNIELTRYTRPTPVQKHAIPIIKGKRDLMACAQTGSGKTAAFLLPILSQI
Sbjct: 181 SDIDMGEIIMGNIELTRYTRPTPVQKHAIPIIKGKRDLMACAQTGSGKTAAFLLPILSQI 240

Query: 241 YTDGPGEALKAVKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYG 300
           YTDGPGEALKAVKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYG
Sbjct: 241 YTDGPGEALKAVKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYG 300

Query: 301 GADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIR 360
           GADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIR
Sbjct: 301 GADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIR 360

Query: 361 RIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVVWV 420
           RIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVVWV
Sbjct: 361 RIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVVWV 420

Query: 421 EDLDKRSFLLDILGATGSDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREE 480
           EDLDKRSFLLDILGATGSDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREE
Sbjct: 421 EDLDKRSFLLDILGATGSDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREE 480

Query: 481 ALHQFRSGKSPILVATAVAARGLDISNVRHVINFDLPSDIEEYVHRIGRTGRVGNLGLAT 540
           ALHQFRSGKSPILVATAVAARGLDISNVRHVINFDLPSDIEEYVHRIGRTGRVGNLGLAT
Sbjct: 481 ALHQFRSGKSPILVATAVAARGLDISNVRHVINFDLPSDIEEYVHRIGRTGRVGNLGLAT 540

Query: 541 SFFNEKNMNITKDLLDLLVEAKQEVPSWLENMAYEHHYKGGSRGRSKSNRFSGGFGARDY 600
           SFFNEKNMNITKDLLDLLVEAKQEVPSWLENMAYEHHYKGGSRGRSKSNRFSGGFGARDY
Sbjct: 541 SFFNEKNMNITKDLLDLLVEAKQEVPSWLENMAYEHHYKGGSRGRSKSNRFSGGFGARDY 600

Query: 601 RQSSGSSSSGFGASRGSSSRSGGGGYGNSRGFGGGGYGGFYNSDGYGGNYNSQGVDWWGN 660
           RQSSGSSSSGFGASRGSSSRSGGGGYGNSRGFGGGGYGGFYNSDGYGGNYNSQGVDWWGN
Sbjct: 601 RQSSGSSSSGFGASRGSSSRSGGGGYGNSRGFGGGGYGGFYNSDGYGGNYNSQGVDWWGN 660


>gi|13514809 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
           [Homo sapiens]
          Length = 660

 Score = 1349 bits (3492), Expect = 0.0
 Identities = 660/660 (100%), Positives = 660/660 (100%)

Query: 1   MSHVVVKNDPELDQQLANLDLNSEKQSGGASTASKGRYIPPHLRNREASKGFHDKDSSGW 60
           MSHVVVKNDPELDQQLANLDLNSEKQSGGASTASKGRYIPPHLRNREASKGFHDKDSSGW
Sbjct: 1   MSHVVVKNDPELDQQLANLDLNSEKQSGGASTASKGRYIPPHLRNREASKGFHDKDSSGW 60

Query: 61  SCSKDKDAYSSFGSRDSRGKPGYFSERGSGSRGRFDDRGRSDYDGIGNRERPGFGRFERS 120
           SCSKDKDAYSSFGSRDSRGKPGYFSERGSGSRGRFDDRGRSDYDGIGNRERPGFGRFERS
Sbjct: 61  SCSKDKDAYSSFGSRDSRGKPGYFSERGSGSRGRFDDRGRSDYDGIGNRERPGFGRFERS 120

Query: 121 GHSRWCDKSVEDDWSKPLPPSERLEQELFSGGNTGINFEKYDDIPVEATGSNCPPHIENF 180
           GHSRWCDKSVEDDWSKPLPPSERLEQELFSGGNTGINFEKYDDIPVEATGSNCPPHIENF
Sbjct: 121 GHSRWCDKSVEDDWSKPLPPSERLEQELFSGGNTGINFEKYDDIPVEATGSNCPPHIENF 180

Query: 181 SDIDMGEIIMGNIELTRYTRPTPVQKHAIPIIKGKRDLMACAQTGSGKTAAFLLPILSQI 240
           SDIDMGEIIMGNIELTRYTRPTPVQKHAIPIIKGKRDLMACAQTGSGKTAAFLLPILSQI
Sbjct: 181 SDIDMGEIIMGNIELTRYTRPTPVQKHAIPIIKGKRDLMACAQTGSGKTAAFLLPILSQI 240

Query: 241 YTDGPGEALKAVKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYG 300
           YTDGPGEALKAVKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYG
Sbjct: 241 YTDGPGEALKAVKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYG 300

Query: 301 GADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIR 360
           GADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIR
Sbjct: 301 GADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIR 360

Query: 361 RIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVVWV 420
           RIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVVWV
Sbjct: 361 RIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVVWV 420

Query: 421 EDLDKRSFLLDILGATGSDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREE 480
           EDLDKRSFLLDILGATGSDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREE
Sbjct: 421 EDLDKRSFLLDILGATGSDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREE 480

Query: 481 ALHQFRSGKSPILVATAVAARGLDISNVRHVINFDLPSDIEEYVHRIGRTGRVGNLGLAT 540
           ALHQFRSGKSPILVATAVAARGLDISNVRHVINFDLPSDIEEYVHRIGRTGRVGNLGLAT
Sbjct: 481 ALHQFRSGKSPILVATAVAARGLDISNVRHVINFDLPSDIEEYVHRIGRTGRVGNLGLAT 540

Query: 541 SFFNEKNMNITKDLLDLLVEAKQEVPSWLENMAYEHHYKGGSRGRSKSNRFSGGFGARDY 600
           SFFNEKNMNITKDLLDLLVEAKQEVPSWLENMAYEHHYKGGSRGRSKSNRFSGGFGARDY
Sbjct: 541 SFFNEKNMNITKDLLDLLVEAKQEVPSWLENMAYEHHYKGGSRGRSKSNRFSGGFGARDY 600

Query: 601 RQSSGSSSSGFGASRGSSSRSGGGGYGNSRGFGGGGYGGFYNSDGYGGNYNSQGVDWWGN 660
           RQSSGSSSSGFGASRGSSSRSGGGGYGNSRGFGGGGYGGFYNSDGYGGNYNSQGVDWWGN
Sbjct: 601 RQSSGSSSSGFGASRGSSSRSGGGGYGNSRGFGGGGYGGFYNSDGYGGNYNSQGVDWWGN 660


>gi|87196351 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3 [Homo
           sapiens]
          Length = 662

 Score = 1241 bits (3210), Expect = 0.0
 Identities = 608/662 (91%), Positives = 634/662 (95%), Gaps = 2/662 (0%)

Query: 1   MSHVVVKNDPELDQQLANLDLNSEKQSGGASTASKGRYIPPHLRNREASKGFHDKDSSGW 60
           MSHV V+N   LDQQ A LDLNS     G STASKGRYIPPHLRNREA+KGF+DKDSSGW
Sbjct: 1   MSHVAVENALGLDQQFAGLDLNSSDNQSGGSTASKGRYIPPHLRNREATKGFYDKDSSGW 60

Query: 61  SCSKDKDAYSSFGSR-DSRGKPGYFSERGSGSRGRFDDRGRSDYDGIGNR-ERPGFGRFE 118
           S SKDKDAYSSFGSR DSRGK  +FS+RGSGSRGRFDDRGRSDYDGIG+R +R GFG+FE
Sbjct: 61  SSSKDKDAYSSFGSRSDSRGKSSFFSDRGSGSRGRFDDRGRSDYDGIGSRGDRSGFGKFE 120

Query: 119 RSGHSRWCDKSVEDDWSKPLPPSERLEQELFSGGNTGINFEKYDDIPVEATGSNCPPHIE 178
           R G+SRWCDKS EDDWSKPLPPSERLEQELFSGGNTGINFEKYDDIPVEATG+NCPPHIE
Sbjct: 121 RGGNSRWCDKSDEDDWSKPLPPSERLEQELFSGGNTGINFEKYDDIPVEATGNNCPPHIE 180

Query: 179 NFSDIDMGEIIMGNIELTRYTRPTPVQKHAIPIIKGKRDLMACAQTGSGKTAAFLLPILS 238
           +FSD++MGEIIMGNIELTRYTRPTPVQKHAIPIIK KRDLMACAQTGSGKTAAFLLPILS
Sbjct: 181 SFSDVEMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPILS 240

Query: 239 QIYTDGPGEALKAVKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVV 298
           QIY+DGPGEAL+A+KENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVV
Sbjct: 241 QIYSDGPGEALRAMKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVV 300

Query: 299 YGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQ 358
           YGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQ
Sbjct: 301 YGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQ 360

Query: 359 IRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVV 418
           IRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVV
Sbjct: 361 IRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVV 420

Query: 419 WVEDLDKRSFLLDILGATGSDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDR 478
           WVE+ DKRSFLLD+L ATG DSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDR
Sbjct: 421 WVEESDKRSFLLDLLNATGKDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDR 480

Query: 479 EEALHQFRSGKSPILVATAVAARGLDISNVRHVINFDLPSDIEEYVHRIGRTGRVGNLGL 538
           EEALHQFRSGKSPILVATAVAARGLDISNV+HVINFDLPSDIEEYVHRIGRTGRVGNLGL
Sbjct: 481 EEALHQFRSGKSPILVATAVAARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGL 540

Query: 539 ATSFFNEKNMNITKDLLDLLVEAKQEVPSWLENMAYEHHYKGGSRGRSKSNRFSGGFGAR 598
           ATSFFNE+N+NITKDLLDLLVEAKQEVPSWLENMAYEHHYKG SRGRSKS+RFSGGFGAR
Sbjct: 541 ATSFFNERNINITKDLLDLLVEAKQEVPSWLENMAYEHHYKGSSRGRSKSSRFSGGFGAR 600

Query: 599 DYRQSSGSSSSGFGASRGSSSRSGGGGYGNSRGFGGGGYGGFYNSDGYGGNYNSQGVDWW 658
           DYRQSSG+SSS F +SR SSSRSGGGG+G+SRGFGGGGYGGFYNSDGYGGNYNSQGVDWW
Sbjct: 601 DYRQSSGASSSSFSSSRASSSRSGGGGHGSSRGFGGGGYGGFYNSDGYGGNYNSQGVDWW 660

Query: 659 GN 660
           GN
Sbjct: 661 GN 662


>gi|209862869 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 3
           [Homo sapiens]
          Length = 724

 Score =  446 bits (1147), Expect = e-125
 Identities = 258/539 (47%), Positives = 347/539 (64%), Gaps = 33/539 (6%)

Query: 85  SERGSGSRGRFDDRGRSDYDGIGNRERPGFGR----FERSGHSRWCDKSVEDDWSKPLPP 140
           S  GSGS        R  Y G+      G G+     E  G      +  +  +  P PP
Sbjct: 200 SRSGSGSE-------RGGYKGLNEEVITGSGKNSWKSEAEGGESSDTQGPKVTYIPPPPP 252

Query: 141 SERLEQELFSGGNTGINFEKYDDIPVEATGSNCPPHIENFSDIDMGEIIMGNIELTRYTR 200
            +  E  +F+   TGINF+KYD I VE +G + PP I  F + ++ + +  NI    YT+
Sbjct: 253 ED--EDSIFAHYQTGINFDKYDTILVEVSGHDAPPAILTFEEANLCQTLNNNIAKAGYTK 310

Query: 201 PTPVQKHAIPIIKGKRDLMACAQTGSGKTAAFLLPILSQIYTDG-PGEALKAVKENGRYG 259
            TPVQK++IPII   RDLMACAQTGSGKTAAFLLPIL+ +  DG      K ++E     
Sbjct: 311 LTPVQKYSIPIILAGRDLMACAQTGSGKTAAFLLPILAHMMHDGITASRFKELQE----- 365

Query: 260 RRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQIRDLERGCHLLV 319
                P  +++APTREL  QIY EARKFS+ + VR  V+YGG  +G  IR + +GC++L 
Sbjct: 366 -----PECIIVAPTRELVNQIYLEARKFSFGTCVRAVVIYGGTQLGHSIRQIVQGCNILC 420

Query: 320 ATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMF 379
           ATPGRL+D++ + KIGL   KYLVLDEADRMLDMGF P++++++    MP K  R T+MF
Sbjct: 421 ATPGRLMDIIGKEKIGLKQIKYLVLDEADRMLDMGFGPEMKKLISCPGMPSKEQRQTLMF 480

Query: 380 SATFPKEIQMLARDFL-DEYIFLAVGRVGSTSENITQKVVWVEDLDKRSFLLDILGATGS 438
           SATFP+EIQ LA +FL   Y+F+AVG+VG    ++ Q V+ V    KR  L++IL   G 
Sbjct: 481 SATFPEEIQRLAAEFLKSNYLFVAVGQVGGACRDVQQTVLQVGQFSKREKLVEILRNIG- 539

Query: 439 DSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAV 498
           D  T+VFVETKK AD +  FL  E  + TSIHGDR QR+RE+AL  FR GK P+LVAT+V
Sbjct: 540 DERTMVFVETKKKADFIATFLCQEKISTTSIHGDREQREREQALGDFRFGKCPVLVATSV 599

Query: 499 AARGLDISNVRHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFN-EKNMNITKDLLDL 557
           AARGLDI NV+HVINFDLPS I+EYVHRIGRTGR GN G A SFF+ E + ++ + L+ +
Sbjct: 600 AARGLDIENVQHVINFDLPSTIDEYVHRIGRTGRCGNTGRAISFFDLESDNHLAQPLVKV 659

Query: 558 LVEAKQEVPSWLENMAYEHHYKGGSRGRSKSNRFSGGFGARDYRQSSGS-SSSGFGASR 615
           L +A+Q+VP+WLE +A+  +  G S G ++ N F+    + D R+   + +++GF +S+
Sbjct: 660 LTDAQQDVPAWLEEIAFSTYIPGFS-GSTRGNVFA----SVDTRKGKSTLNTAGFSSSQ 713



 Score = 30.0 bits (66), Expect = 7.1
 Identities = 23/68 (33%), Positives = 32/68 (47%), Gaps = 10/68 (14%)

Query: 575 EHHYKGG-SRGRSKSNRFSGGFGARDYRQSSGSSSSGFGASRGSSSRSGGGGYGNSRGFG 633
           +H  K G + GR+  NR +G    RD   + G    GFG  +   +R    G+ NSR F 
Sbjct: 52  DHFMKSGFASGRNFGNRDAGECNKRDNTSTMG----GFGVGKSFGNR----GFSNSR-FE 102

Query: 634 GGGYGGFY 641
            G   GF+
Sbjct: 103 DGDSSGFW 110



 Score = 30.0 bits (66), Expect = 7.1
 Identities = 24/68 (35%), Positives = 29/68 (42%), Gaps = 4/68 (5%)

Query: 581 GSRGRSKSNRFSGGFGARDYRQSSGSSSSGFGASRGSSSRSGGGGYGNSRGFG---GGGY 637
           G+RG S S RF  G  +  +R+SS         +RG S R G     NS   G    GG 
Sbjct: 92  GNRGFSNS-RFEDGDSSGFWRESSNDCEDNPTRNRGFSKRGGYRDGNNSEASGPYRRGGR 150

Query: 638 GGFYNSDG 645
           G F    G
Sbjct: 151 GSFRGCRG 158


>gi|13518015 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 1
           [Homo sapiens]
          Length = 724

 Score =  446 bits (1147), Expect = e-125
 Identities = 258/539 (47%), Positives = 347/539 (64%), Gaps = 33/539 (6%)

Query: 85  SERGSGSRGRFDDRGRSDYDGIGNRERPGFGR----FERSGHSRWCDKSVEDDWSKPLPP 140
           S  GSGS        R  Y G+      G G+     E  G      +  +  +  P PP
Sbjct: 200 SRSGSGSE-------RGGYKGLNEEVITGSGKNSWKSEAEGGESSDTQGPKVTYIPPPPP 252

Query: 141 SERLEQELFSGGNTGINFEKYDDIPVEATGSNCPPHIENFSDIDMGEIIMGNIELTRYTR 200
            +  E  +F+   TGINF+KYD I VE +G + PP I  F + ++ + +  NI    YT+
Sbjct: 253 ED--EDSIFAHYQTGINFDKYDTILVEVSGHDAPPAILTFEEANLCQTLNNNIAKAGYTK 310

Query: 201 PTPVQKHAIPIIKGKRDLMACAQTGSGKTAAFLLPILSQIYTDG-PGEALKAVKENGRYG 259
            TPVQK++IPII   RDLMACAQTGSGKTAAFLLPIL+ +  DG      K ++E     
Sbjct: 311 LTPVQKYSIPIILAGRDLMACAQTGSGKTAAFLLPILAHMMHDGITASRFKELQE----- 365

Query: 260 RRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQIRDLERGCHLLV 319
                P  +++APTREL  QIY EARKFS+ + VR  V+YGG  +G  IR + +GC++L 
Sbjct: 366 -----PECIIVAPTRELVNQIYLEARKFSFGTCVRAVVIYGGTQLGHSIRQIVQGCNILC 420

Query: 320 ATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMF 379
           ATPGRL+D++ + KIGL   KYLVLDEADRMLDMGF P++++++    MP K  R T+MF
Sbjct: 421 ATPGRLMDIIGKEKIGLKQIKYLVLDEADRMLDMGFGPEMKKLISCPGMPSKEQRQTLMF 480

Query: 380 SATFPKEIQMLARDFL-DEYIFLAVGRVGSTSENITQKVVWVEDLDKRSFLLDILGATGS 438
           SATFP+EIQ LA +FL   Y+F+AVG+VG    ++ Q V+ V    KR  L++IL   G 
Sbjct: 481 SATFPEEIQRLAAEFLKSNYLFVAVGQVGGACRDVQQTVLQVGQFSKREKLVEILRNIG- 539

Query: 439 DSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAV 498
           D  T+VFVETKK AD +  FL  E  + TSIHGDR QR+RE+AL  FR GK P+LVAT+V
Sbjct: 540 DERTMVFVETKKKADFIATFLCQEKISTTSIHGDREQREREQALGDFRFGKCPVLVATSV 599

Query: 499 AARGLDISNVRHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFN-EKNMNITKDLLDL 557
           AARGLDI NV+HVINFDLPS I+EYVHRIGRTGR GN G A SFF+ E + ++ + L+ +
Sbjct: 600 AARGLDIENVQHVINFDLPSTIDEYVHRIGRTGRCGNTGRAISFFDLESDNHLAQPLVKV 659

Query: 558 LVEAKQEVPSWLENMAYEHHYKGGSRGRSKSNRFSGGFGARDYRQSSGS-SSSGFGASR 615
           L +A+Q+VP+WLE +A+  +  G S G ++ N F+    + D R+   + +++GF +S+
Sbjct: 660 LTDAQQDVPAWLEEIAFSTYIPGFS-GSTRGNVFA----SVDTRKGKSTLNTAGFSSSQ 713



 Score = 30.0 bits (66), Expect = 7.1
 Identities = 23/68 (33%), Positives = 32/68 (47%), Gaps = 10/68 (14%)

Query: 575 EHHYKGG-SRGRSKSNRFSGGFGARDYRQSSGSSSSGFGASRGSSSRSGGGGYGNSRGFG 633
           +H  K G + GR+  NR +G    RD   + G    GFG  +   +R    G+ NSR F 
Sbjct: 52  DHFMKSGFASGRNFGNRDAGECNKRDNTSTMG----GFGVGKSFGNR----GFSNSR-FE 102

Query: 634 GGGYGGFY 641
            G   GF+
Sbjct: 103 DGDSSGFW 110



 Score = 30.0 bits (66), Expect = 7.1
 Identities = 24/68 (35%), Positives = 29/68 (42%), Gaps = 4/68 (5%)

Query: 581 GSRGRSKSNRFSGGFGARDYRQSSGSSSSGFGASRGSSSRSGGGGYGNSRGFG---GGGY 637
           G+RG S S RF  G  +  +R+SS         +RG S R G     NS   G    GG 
Sbjct: 92  GNRGFSNS-RFEDGDSSGFWRESSNDCEDNPTRNRGFSKRGGYRDGNNSEASGPYRRGGR 150

Query: 638 GGFYNSDG 645
           G F    G
Sbjct: 151 GSFRGCRG 158


>gi|216548263 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 2
           [Homo sapiens]
          Length = 690

 Score =  446 bits (1147), Expect = e-125
 Identities = 258/539 (47%), Positives = 347/539 (64%), Gaps = 33/539 (6%)

Query: 85  SERGSGSRGRFDDRGRSDYDGIGNRERPGFGR----FERSGHSRWCDKSVEDDWSKPLPP 140
           S  GSGS        R  Y G+      G G+     E  G      +  +  +  P PP
Sbjct: 166 SRSGSGSE-------RGGYKGLNEEVITGSGKNSWKSEAEGGESSDTQGPKVTYIPPPPP 218

Query: 141 SERLEQELFSGGNTGINFEKYDDIPVEATGSNCPPHIENFSDIDMGEIIMGNIELTRYTR 200
            +  E  +F+   TGINF+KYD I VE +G + PP I  F + ++ + +  NI    YT+
Sbjct: 219 ED--EDSIFAHYQTGINFDKYDTILVEVSGHDAPPAILTFEEANLCQTLNNNIAKAGYTK 276

Query: 201 PTPVQKHAIPIIKGKRDLMACAQTGSGKTAAFLLPILSQIYTDG-PGEALKAVKENGRYG 259
            TPVQK++IPII   RDLMACAQTGSGKTAAFLLPIL+ +  DG      K ++E     
Sbjct: 277 LTPVQKYSIPIILAGRDLMACAQTGSGKTAAFLLPILAHMMHDGITASRFKELQE----- 331

Query: 260 RRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQIRDLERGCHLLV 319
                P  +++APTREL  QIY EARKFS+ + VR  V+YGG  +G  IR + +GC++L 
Sbjct: 332 -----PECIIVAPTRELVNQIYLEARKFSFGTCVRAVVIYGGTQLGHSIRQIVQGCNILC 386

Query: 320 ATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMF 379
           ATPGRL+D++ + KIGL   KYLVLDEADRMLDMGF P++++++    MP K  R T+MF
Sbjct: 387 ATPGRLMDIIGKEKIGLKQIKYLVLDEADRMLDMGFGPEMKKLISCPGMPSKEQRQTLMF 446

Query: 380 SATFPKEIQMLARDFL-DEYIFLAVGRVGSTSENITQKVVWVEDLDKRSFLLDILGATGS 438
           SATFP+EIQ LA +FL   Y+F+AVG+VG    ++ Q V+ V    KR  L++IL   G 
Sbjct: 447 SATFPEEIQRLAAEFLKSNYLFVAVGQVGGACRDVQQTVLQVGQFSKREKLVEILRNIG- 505

Query: 439 DSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAV 498
           D  T+VFVETKK AD +  FL  E  + TSIHGDR QR+RE+AL  FR GK P+LVAT+V
Sbjct: 506 DERTMVFVETKKKADFIATFLCQEKISTTSIHGDREQREREQALGDFRFGKCPVLVATSV 565

Query: 499 AARGLDISNVRHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFN-EKNMNITKDLLDL 557
           AARGLDI NV+HVINFDLPS I+EYVHRIGRTGR GN G A SFF+ E + ++ + L+ +
Sbjct: 566 AARGLDIENVQHVINFDLPSTIDEYVHRIGRTGRCGNTGRAISFFDLESDNHLAQPLVKV 625

Query: 558 LVEAKQEVPSWLENMAYEHHYKGGSRGRSKSNRFSGGFGARDYRQSSGS-SSSGFGASR 615
           L +A+Q+VP+WLE +A+  +  G S G ++ N F+    + D R+   + +++GF +S+
Sbjct: 626 LTDAQQDVPAWLEEIAFSTYIPGFS-GSTRGNVFA----SVDTRKGKSTLNTAGFSSSQ 679



 Score = 30.0 bits (66), Expect = 7.1
 Identities = 23/68 (33%), Positives = 32/68 (47%), Gaps = 10/68 (14%)

Query: 575 EHHYKGG-SRGRSKSNRFSGGFGARDYRQSSGSSSSGFGASRGSSSRSGGGGYGNSRGFG 633
           +H  K G + GR+  NR +G    RD   + G    GFG  +   +R    G+ NSR F 
Sbjct: 52  DHFMKSGFASGRNFGNRDAGECNKRDNTSTMG----GFGVGKSFGNR----GFSNSR-FE 102

Query: 634 GGGYGGFY 641
            G   GF+
Sbjct: 103 DGDSSGFW 110


>gi|4758138 DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 [Homo sapiens]
          Length = 614

 Score =  328 bits (842), Expect = 7e-90
 Identities = 223/589 (37%), Positives = 313/589 (53%), Gaps = 52/589 (8%)

Query: 82  GYFSERGSGSRGRFDDRGRSDYDGIGNRERPGFGR-FERSGHSRWCDKSVEDDWS-KPLP 139
           GY S+R    RGR  DRG       G+R  P  G+ F   G     +K V+  W+   LP
Sbjct: 3   GYSSDR---DRGR--DRGFGAPRFGGSRAGPLSGKKFGNPG-----EKLVKKKWNLDELP 52

Query: 140 PSER--LEQELFSGGNTGINFEKYD-DIPVEATGSNCPPHIENFSDIDMGEIIMGNIELT 196
             E+   ++       T    E Y     +   G NCP  + NF + +    +M  I   
Sbjct: 53  KFEKNFYQEHPDLARRTAQEVETYRRSKEITVRGHNCPKPVLNFYEANFPANVMDVIARQ 112

Query: 197 RYTRPTPVQKHAIPIIKGKRDLMACAQTGSGKTAAFLLPILSQIYTDGPGEALKAVKENG 256
            +T PT +Q    P+     D++  AQTGSGKT ++LLP +  I              + 
Sbjct: 113 NFTEPTAIQAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAIVHI-------------NHQ 159

Query: 257 RYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQIRDLERGCH 316
            +  R   PI LVLAPTRELA Q+ + A ++    R++   +YGGA  G QIRDLERG  
Sbjct: 160 PFLERGDGPICLVLAPTRELAQQVQQVAAEYCRACRLKSTCIYGGAPKGPQIRDLERGVE 219

Query: 317 LLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHT 376
           + +ATPGRL+D +E GK  L    YLVLDEADRMLDMGFEPQIR+IV+Q     +  R T
Sbjct: 220 ICIATPGRLIDFLECGKTNLRRTTYLVLDEADRMLDMGFEPQIRKIVDQI----RPDRQT 275

Query: 377 MMFSATFPKEIQMLARDFLDEYIFLAVGRVG-STSENITQKVVWVEDLDKRSFLLDILGA 435
           +M+SAT+PKE++ LA DFL +YI + +G +  S + NI Q V    D++K   L+ ++  
Sbjct: 276 LMWSATWPKEVRQLAEDFLKDYIHINIGALELSANHNILQIVDVCHDVEKDEKLIRLMEE 335

Query: 436 TGSD--SLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPIL 493
             S+  + T+VFVETK+  D L   +  +G+    IHGD+SQ++R+  L++F+ GK+PIL
Sbjct: 336 IMSEKENKTIVFVETKRRCDELTRKMRRDGWPAMGIHGDKSQQERDWVLNEFKHGKAPIL 395

Query: 494 VATAVAARGLDISNVRHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNEKNMNITKD 553
           +AT VA+RGLD+ +V+ VIN+D P+  E+Y+HRIGRT R    G A +FF   N+    D
Sbjct: 396 IATDVASRGLDVEDVKFVINYDYPNSSEDYIHRIGRTARSTKTGTAYTFFTPNNIKQVSD 455

Query: 554 LLDLLVEAKQEVPSWLENMAYEHHYKGGSRGRSKSNRFSGGFGARDYRQS--SGSSSSGF 611
           L+ +L EA Q +   L  +  E    G SRGR          G +D R+   S     GF
Sbjct: 456 LISVLREANQAINPKLLQLV-EDRGSGRSRGRG---------GMKDDRRDRYSAGKRGGF 505

Query: 612 GASRGSSSRSGGGGYGNSRGFGGGGYGGFYNSDGY-----GGNYNSQGV 655
              R   +   G      R FG     G Y++  Y     G N+ S G+
Sbjct: 506 NTFRDRENYDRGYSSLLKRDFGAKTQNGVYSAANYTNGSFGSNFVSAGI 554


>gi|38201710 DEAD box polypeptide 17 isoform 1 [Homo sapiens]
          Length = 729

 Score =  325 bits (834), Expect = 6e-89
 Identities = 202/508 (39%), Positives = 280/508 (55%), Gaps = 41/508 (8%)

Query: 170 GSNCPPHIENFSDIDMGEIIMGNIELTRYTRPTPVQKHAIPIIKGKRDLMACAQTGSGKT 229
           G  CP  +  F   +  + +M  +    +T PTP+Q    P+    RD++  AQTGSGKT
Sbjct: 163 GDVCPKPVFAFHHANFPQYVMDVLMDQHFTEPTPIQCQGFPLALSGRDMVGIAQTGSGKT 222

Query: 230 AAFLLPILSQIYTDGPGEALKAVKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSY 289
            A+LLP +  I              +  Y  R   PI LVLAPTRELA Q+ + A  +  
Sbjct: 223 LAYLLPAIVHI-------------NHQPYLERGDGPICLVLAPTRELAQQVQQVADDYGK 269

Query: 290 RSRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADR 349
            SR++   +YGGA  G QIRDLERG  + +ATPGRL+D +E GK  L  C YLVLDEADR
Sbjct: 270 CSRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLESGKTNLRRCTYLVLDEADR 329

Query: 350 MLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVG-S 408
           MLDMGFEPQIR+IV+Q     +  R T+M+SAT+PKE++ LA DFL +Y  + VG +  S
Sbjct: 330 MLDMGFEPQIRKIVDQI----RPDRQTLMWSATWPKEVRQLAEDFLRDYTQINVGNLELS 385

Query: 409 TSENITQKVVWVEDLDKRSFLLDILGA--TGSDSLTLVFVETKKGADSLEDFLYHEGYAC 466
            + NI Q V    + +K   L+ ++       ++ T++FVETK+  D L   +  +G+  
Sbjct: 386 ANHNILQIVDVCMESEKDHKLIQLMEEIMAEKENKTIIFVETKRRCDDLTRRMRRDGWPA 445

Query: 467 TSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVRHVINFDLPSDIEEYVHR 526
             IHGD+SQ +R+  L++FRSGK+PIL+AT VA+RGLD+ +V+ VIN+D P+  E+YVHR
Sbjct: 446 MCIHGDKSQPERDWVLNEFRSGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYVHR 505

Query: 527 IGRTGRVGNLGLATSFFNEKNMNITKDLLDLLVEAKQEVPSWLENMAYEHHYKGGSRGRS 586
           IGRT R  N G A +FF   N+   ++L+ +L EA Q +   L  +       GG  GRS
Sbjct: 506 IGRTARSTNKGTAYTFFTPGNLKQARELIKVLEEANQAINPKLMQLVDHRGGGGGGGGRS 565

Query: 587 KSNRFSGGFGAR-------DYR----QSSGSSSSGFGASRGSSSRSG---GGGYGNSRGF 632
           +    S             D R    +  G   S     R  + R+G   G GYG+    
Sbjct: 566 RYRTTSSANNPNLMYQDECDRRLRGVKDGGRRDSASYRDRSETDRAGYANGSGYGSPNSA 625

Query: 633 GGGGYG------GFYNSDGYG-GNYNSQ 653
            G   G      G Y +  YG  +Y +Q
Sbjct: 626 FGAQAGQYTYGQGTYGAAAYGTSSYTAQ 653


>gi|148613856 DEAD box polypeptide 17 isoform 3 [Homo sapiens]
          Length = 731

 Score =  325 bits (833), Expect = 8e-89
 Identities = 200/511 (39%), Positives = 282/511 (55%), Gaps = 45/511 (8%)

Query: 170 GSNCPPHIENFSDIDMGEIIMGNIELTRYTRPTPVQKHAIPIIKGKRDLMACAQTGSGKT 229
           G  CP  +  F   +  + +M  +    +T PTP+Q    P+    RD++  AQTGSGKT
Sbjct: 163 GDVCPKPVFAFHHANFPQYVMDVLMDQHFTEPTPIQCQGFPLALSGRDMVGIAQTGSGKT 222

Query: 230 AAFLLPILSQIYTDGPGEALKAVKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSY 289
            A+LLP +  I              +  Y  R   PI LVLAPTRELA Q+ + A  +  
Sbjct: 223 LAYLLPAIVHI-------------NHQPYLERGDGPICLVLAPTRELAQQVQQVADDYGK 269

Query: 290 RSRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADR 349
            SR++   +YGGA  G QIRDLERG  + +ATPGRL+D +E GK  L  C YLVLDEADR
Sbjct: 270 CSRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLESGKTNLRRCTYLVLDEADR 329

Query: 350 MLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVG-S 408
           MLDMGFEPQIR+IV+Q     +  R T+M+SAT+PKE++ LA DFL +Y  + VG +  S
Sbjct: 330 MLDMGFEPQIRKIVDQ----IRPDRQTLMWSATWPKEVRQLAEDFLRDYTQINVGNLELS 385

Query: 409 TSENITQKVVWVEDLDKRSFLLDILG--ATGSDSLTLVFVETKKGADSLEDFLYHEGYAC 466
            + NI Q V    + +K   L+ ++       ++ T++FVETK+  D L   +  +G+  
Sbjct: 386 ANHNILQIVDVCMESEKDHKLIQLMEEIMAEKENKTIIFVETKRRCDDLTRRMRRDGWPA 445

Query: 467 TSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVRHVINFDLPSDIEEYVHR 526
             IHGD+SQ +R+  L++FRSGK+PIL+AT VA+RGLD+ +V+ VIN+D P+  E+YVHR
Sbjct: 446 MCIHGDKSQPERDWVLNEFRSGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYVHR 505

Query: 527 IGRTGRVGNLGLATSFFNEKNMNITKDLLDLLVEAKQEVPSWLENMAYEHHYKGGSRGRS 586
           IGRT R  N G A +FF   N+   ++L+ +L EA Q +   L  +  +H   GG  G+ 
Sbjct: 506 IGRTARSTNKGTAYTFFTPGNLKQARELIKVLEEANQAINPKLMQLV-DHRGGGGGGGKG 564

Query: 587 KSNRFSGGFGARDYR--------------QSSGSSSSGFGASRGSSSRSG---GGGYGNS 629
             +R+     A +                +  G   S     R  + R+G   G GYG+ 
Sbjct: 565 GRSRYRTTSSANNPNLMYQDECDRRLRGVKDGGRRDSASYRDRSETDRAGYANGSGYGSP 624

Query: 630 RGFGGGGYG------GFYNSDGYG-GNYNSQ 653
               G   G      G Y +  YG  +Y +Q
Sbjct: 625 NSAFGAQAGQYTYGQGTYGAAAYGTSSYTAQ 655


>gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo
           sapiens]
          Length = 1031

 Score =  289 bits (739), Expect = 6e-78
 Identities = 170/458 (37%), Positives = 259/458 (56%), Gaps = 22/458 (4%)

Query: 147 ELFSGGNTGINFEKYDDIPVEATGSNCPPHIENFSDIDMGEIIMGNIELTRYTRPTPVQK 206
           EL       +N  + +   +   G  CP  I+++    +   I+ +++   Y +PTP+Q 
Sbjct: 341 ELAKMSQEEVNVFRLEMEGITVKGKGCPKPIKSWVQCGISMKILNSLKKHGYEKPTPIQT 400

Query: 207 HAIPIIKGKRDLMACAQTGSGKTAAFLLPILSQIYTDGPGEALKAVKENGRYGRRKQYPI 266
            AIP I   RDL+  A+TGSGKT AFLLP+   I         ++++E        + PI
Sbjct: 401 QAIPAIMSGRDLIGIAKTGSGKTIAFLLPMFRHIMDQ------RSLEEG-------EGPI 447

Query: 267 SLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLV 326
           ++++ PTRELA+QI +E +KFS    +R   VYGG  I +QI +L+RG  ++V TPGR++
Sbjct: 448 AVIMTPTRELALQITKECKKFSKTLGLRVVCVYGGTGISEQIAELKRGAEIIVCTPGRMI 507

Query: 327 DMM--ERGKI-GLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATF 383
           DM+    G++  L    Y+VLDEADRM DMGFEPQ+ RIV  D + P   R T+MFSATF
Sbjct: 508 DMLAANSGRVTNLRRVTYVVLDEADRMFDMGFEPQVMRIV--DNVRPD--RQTVMFSATF 563

Query: 384 PKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVVWVEDLDKRSFLLDILGATGSDSLTL 443
           P+ ++ LAR  L + I + VG       ++ Q+V+ +E+  K   LL++LG        +
Sbjct: 564 PRAMEALARRILSKPIEVQVGGRSVVCSDVEQQVIVIEEEKKFLKLLELLGHYQESGSVI 623

Query: 444 VFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGL 503
           +FV+ ++ AD L   L    Y C S+HG   Q DR+  ++ F++G   +LVAT+VAARGL
Sbjct: 624 IFVDKQEHADGLLKDLMRASYPCMSLHGGIDQYDRDSIINDFKNGTCKLLVATSVAARGL 683

Query: 504 DISNVRHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNEKNMNITKDLLDLLVEAKQ 563
           D+ ++  V+N+  P+  E+YVHR GRTGR GN G A +F  E       D++  L  +  
Sbjct: 684 DVKHLILVVNYSCPNHYEDYVHRAGRTGRAGNKGYAYTFITEDQARYAGDIIKALELSGT 743

Query: 564 EVPSWLENMAYEHHYKGGSRGRSKSNRFSGGFGARDYR 601
            VP  LE +  +  +K   +   K  + S GF  + ++
Sbjct: 744 AVPPDLEKLWSD--FKDQQKAEGKIIKKSSGFSGKGFK 779


>gi|21071032 DEAD-box protein abstrakt [Homo sapiens]
          Length = 622

 Score =  288 bits (736), Expect = 1e-77
 Identities = 169/439 (38%), Positives = 252/439 (57%), Gaps = 30/439 (6%)

Query: 170 GSNCPPHIENFSDIDMGEIIMGNIELTRYTRPTPVQKHAIPIIKGKRDLMACAQTGSGKT 229
           G   PP I++F ++     I+  ++      PTP+Q   IP I   RD++  A TGSGKT
Sbjct: 173 GDGIPPPIKSFKEMKFPAAILRGLKKKGIHHPTPIQIQGIPTILSGRDMIGIAFTGSGKT 232

Query: 230 AAFLLPILSQIYTDGPGEALKAVKENGRYGRRKQYPISLVLAPTRELA------VQIYEE 283
             F LP++  ++     + L   K  G YG        L++ P+RELA      ++ Y  
Sbjct: 233 LVFTLPVI--MFCLEQEKRLPFSKREGPYG--------LIICPSRELARQTHGILEYYCR 282

Query: 284 ARKFSYRSRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLV 343
             +      +R  +  GG  + +Q+  +  G H++VATPGRL+D++++  + LD C+YL 
Sbjct: 283 LLQEDSSPLLRCALCIGGMSVKEQMETIRHGVHMMVATPGRLMDLLQKKMVSLDICRYLA 342

Query: 344 LDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAV 403
           LDEADRM+DMGFE  IR I        KG R T++FSAT PK+IQ  A+  L + + + V
Sbjct: 343 LDEADRMIDMGFEGDIRTIFSYF----KGQRQTLLFSATMPKKIQNFAKSALVKPVTINV 398

Query: 404 GRVGSTSENITQKVVWVEDLDKRSFLLDILGATGSDSLTLVFVETKKGADSLEDFLYHEG 463
           GR G+ S ++ Q+V +V++  K  +LL+ L  T      L+F E K   D++ ++L  +G
Sbjct: 399 GRAGAASLDVIQEVEYVKEEAKMVYLLECLQKTPPP--VLIFAEKKADVDAIHEYLLLKG 456

Query: 464 YACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVRHVINFDLPSDIEEY 523
               +IHG + Q +R +A+  FR GK  +LVAT VA++GLD   ++HVIN+D+P +IE Y
Sbjct: 457 VEAVAIHGGKDQEERTKAIEAFREGKKDVLVATDVASKGLDFPAIQHVINYDMPEEIENY 516

Query: 524 VHRIGRTGRVGNLGLATSFFNEK-NMNITKDLLDLLVEAKQEVPSWLENMAYEHHYK--- 579
           VHRIGRTGR GN G+AT+F N+  + ++  DL  LL+EAKQ+VP  L+ +          
Sbjct: 517 VHRIGRTGRSGNTGIATTFINKACDESVLMDLKALLLEAKQKVPPVLQVLHCGDESMLDI 576

Query: 580 GGSRGRSKSNRFSGGFGAR 598
           GG RG +    F GG G R
Sbjct: 577 GGERGCA----FCGGLGHR 591


>gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo
           sapiens]
          Length = 820

 Score =  277 bits (708), Expect = 3e-74
 Identities = 167/442 (37%), Positives = 238/442 (53%), Gaps = 33/442 (7%)

Query: 162 DDIPVEATGSNCPPHIENFSDIDMGEIIMGNIELTRYTRPTPVQKHAIPIIKGKRDLMAC 221
           +D  +   G   P  I ++ D  +   I+  I+   Y  PTP+Q+ AIPI    RD++  
Sbjct: 375 EDYSITTKGGKIPNPIRSWKDSSLPPHILEVIDKCGYKEPTPIQRQAIPIGLQNRDIIGV 434

Query: 222 AQTGSGKTAAFLLPILSQIYTDGPGEALKAVKENGRYGRRKQYPISLVLAPTRELAVQIY 281
           A+TGSGKTAAFL+P+L  I T         + +  R     Q P +++LAPTRELA QI 
Sbjct: 435 AETGSGKTAAFLIPLLVWITT---------LPKIDRIEESDQGPYAIILAPTRELAQQIE 485

Query: 282 EEARKFSYRSRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKY 341
           EE  KF     +R   V GG     Q   L  GC +++ATPGRL+D++E   + L  C Y
Sbjct: 486 EETIKFGKPLGIRTVAVIGGISREDQGFRLRMGCEIVIATPGRLIDVLENRYLVLSRCTY 545

Query: 342 LVLDEADRMLDMGFEPQIRRIVEQDTM------------PPKGV----------RHTMMF 379
           +VLDEADRM+DMGFEP +++I+E   +            P K +          R T+MF
Sbjct: 546 VVLDEADRMIDMGFEPDVQKILEHMPVSNQKPDTDEAEDPEKMLANFESGKHKYRQTVMF 605

Query: 380 SATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVVWVEDLDKRSFLLDILGATGSD 439
           +AT P  ++ LAR +L     + +G  G   E + QKV  + + +KR  LL IL   G D
Sbjct: 606 TATMPPAVERLARSYLRRPAVVYIGSAGKPHERVEQKVFLMSESEKRKKLLAIL-EQGFD 664

Query: 440 SLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAVA 499
              ++FV  KKG D L   L   GY   ++HG + Q  RE AL   ++G   ILVAT VA
Sbjct: 665 PPIIIFVNQKKGCDVLAKSLEKMGYNACTLHGGKGQEQREFALSNLKAGAKDILVATDVA 724

Query: 500 ARGLDISNVRHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNEKNMNITKDLLDLLV 559
            RG+DI +V  V+N+D+  +IE+Y+HRIGRTGR G  G+A +F  +++  +  +L   ++
Sbjct: 725 GRGIDIQDVSMVVNYDMAKNIEDYIHRIGRTGRAGKSGVAITFLTKEDSAVFYELKQAIL 784

Query: 560 EAK-QEVPSWLENMAYEHHYKG 580
           E+     P  L N     H  G
Sbjct: 785 ESPVSSCPPELANHPDAQHKPG 806


>gi|222352149 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 [Homo
           sapiens]
          Length = 648

 Score =  272 bits (696), Expect = 6e-73
 Identities = 157/386 (40%), Positives = 229/386 (59%), Gaps = 18/386 (4%)

Query: 189 IMGNIELTRYTRPTPVQKHAIPIIKGKRDLMACAQTGSGKTAAFLLPILSQIYTDGPGEA 248
           +M NI+   + +PTP+Q  A PI+    DL+  AQTG+GKT  +L+P    +        
Sbjct: 253 VMENIKKAGFQKPTPIQSQAWPIVLQGIDLIGVAQTGTGKTLCYLMPGFIHL-------- 304

Query: 249 LKAVKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQI 308
              V +    G+R + P  LVL PTRELA+Q+  E  K+SY+  +R   VYGG +  +QI
Sbjct: 305 ---VLQPSLKGQRNR-PGMLVLTPTRELALQVEGECCKYSYKG-LRSVCVYGGGNRDEQI 359

Query: 309 RDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTM 368
            +L++G  +++ATPGRL D+     + L    YLVLDEAD+MLDMGFEPQI +I+  D  
Sbjct: 360 EELKKGVDIIIATPGRLNDLQMSNFVNLKNITYLVLDEADKMLDMGFEPQIMKIL-LDVR 418

Query: 369 PPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTS-ENITQKVVWVEDLDKRS 427
           P    R T+M SAT+P  +  LA+ +L E + + VG +   +  ++ Q ++   + +K S
Sbjct: 419 PD---RQTVMTSATWPHSVHRLAQSYLKEPMIVYVGTLDLVAVSSVKQNIIVTTEEEKWS 475

Query: 428 FLLDILGATGSDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRS 487
            +   L +  S    +VFV  K  AD L   L     +  S+HGDR QRDRE+AL  F++
Sbjct: 476 HMQTFLQSMSSTDKVIVFVSRKAVADHLSSDLILGNISVESLHGDREQRDREKALENFKT 535

Query: 488 GKSPILVATAVAARGLDISNVRHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNEKN 547
           GK  IL+AT +A+RGLD+ +V HV NFD P +IEEYVHRIGRTGR G  G++ +     +
Sbjct: 536 GKVRILIATDLASRGLDVHDVTHVYNFDFPRNIEEYVHRIGRTGRAGRTGVSITTLTRND 595

Query: 548 MNITKDLLDLLVEAKQEVPSWLENMA 573
             +  +L+++L  A Q +P  L +MA
Sbjct: 596 WRVASELINILERANQSIPEELVSMA 621


>gi|45446747 DEAD box polypeptide 42 protein [Homo sapiens]
          Length = 938

 Score =  268 bits (686), Expect = 9e-72
 Identities = 165/459 (35%), Positives = 248/459 (54%), Gaps = 27/459 (5%)

Query: 166 VEATGSNCPPHIENFSDIDMGEIIMGNIELTRYTRPTPVQKHAIPIIKGKRDLMACAQTG 225
           +  +G+  P    +F+     E +M  I  + YT+PTP+Q   +P+    RD++  A+TG
Sbjct: 241 LRVSGAAPPRPGSSFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTG 300

Query: 226 SGKTAAFLLPILSQIYTDG---PGEALKAVKENGRYGRRKQYPISLVLAPTRELAVQIYE 282
           SGKTAAF+ P+L  I       PG+                 PI++++ PTREL  QI+ 
Sbjct: 301 SGKTAAFIWPMLIHIMDQKELEPGDG----------------PIAVIVCPTRELCQQIHA 344

Query: 283 EARKFSYRSRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYL 342
           E ++F     +R   VYGG  + +Q + L+ G  ++V TPGRL+D +++    L    YL
Sbjct: 345 ECKRFGKAYNLRSVAVYGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKKKATNLQRVSYL 404

Query: 343 VLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLA 402
           V DEADRM DMGFE Q+R I        +  R T++FSATF K+I+ LARD L + I + 
Sbjct: 405 VFDEADRMFDMGFEYQVRSIASH----VRPDRQTLLFSATFRKKIEKLARDILIDPIRVV 460

Query: 403 VGRVGSTSENITQKV-VWVEDLDKRSFLLDILGATGSDSLTLVFVETKKGADSLEDFLYH 461
            G +G  +E++TQ V +      K ++L   L    S    L+FV  K  A+ L + L  
Sbjct: 461 QGDIGEANEDVTQIVEILHSGPSKWNWLTRRLVEFTSSGSVLLFVTKKANAEELANNLKQ 520

Query: 462 EGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVRHVINFDLPSDIE 521
           EG+    +HGD  Q +R + +  F+    P+LVAT VAARGLDI +++ VIN+D+  DI+
Sbjct: 521 EGHNLGLLHGDMDQSERNKVISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDID 580

Query: 522 EYVHRIGRTGRVGNLGLATSFFNEKNMNITKDLLDLLVEAKQEVPSWLENMAYEHHYKGG 581
            + HRIGRTGR G  G+A +    K+ N   DL+  L  A Q V   L ++A ++ +   
Sbjct: 581 THTHRIGRTGRAGEKGVAYTLLTPKDSNFAGDLVRNLEGANQHVSKELLDLAMQNAWFRK 640

Query: 582 SRGR-SKSNRFSGGFGARDYRQSSGSSSSGFGASRGSSS 619
           SR +  K  + + G G   YR+  G  S      RG+++
Sbjct: 641 SRFKGGKGKKLNIGGGGLGYRERPGLGSENM--DRGNNN 677


>gi|45446743 DEAD box polypeptide 42 protein [Homo sapiens]
          Length = 938

 Score =  268 bits (686), Expect = 9e-72
 Identities = 165/459 (35%), Positives = 248/459 (54%), Gaps = 27/459 (5%)

Query: 166 VEATGSNCPPHIENFSDIDMGEIIMGNIELTRYTRPTPVQKHAIPIIKGKRDLMACAQTG 225
           +  +G+  P    +F+     E +M  I  + YT+PTP+Q   +P+    RD++  A+TG
Sbjct: 241 LRVSGAAPPRPGSSFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTG 300

Query: 226 SGKTAAFLLPILSQIYTDG---PGEALKAVKENGRYGRRKQYPISLVLAPTRELAVQIYE 282
           SGKTAAF+ P+L  I       PG+                 PI++++ PTREL  QI+ 
Sbjct: 301 SGKTAAFIWPMLIHIMDQKELEPGDG----------------PIAVIVCPTRELCQQIHA 344

Query: 283 EARKFSYRSRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYL 342
           E ++F     +R   VYGG  + +Q + L+ G  ++V TPGRL+D +++    L    YL
Sbjct: 345 ECKRFGKAYNLRSVAVYGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKKKATNLQRVSYL 404

Query: 343 VLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLA 402
           V DEADRM DMGFE Q+R I        +  R T++FSATF K+I+ LARD L + I + 
Sbjct: 405 VFDEADRMFDMGFEYQVRSIASH----VRPDRQTLLFSATFRKKIEKLARDILIDPIRVV 460

Query: 403 VGRVGSTSENITQKV-VWVEDLDKRSFLLDILGATGSDSLTLVFVETKKGADSLEDFLYH 461
            G +G  +E++TQ V +      K ++L   L    S    L+FV  K  A+ L + L  
Sbjct: 461 QGDIGEANEDVTQIVEILHSGPSKWNWLTRRLVEFTSSGSVLLFVTKKANAEELANNLKQ 520

Query: 462 EGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVRHVINFDLPSDIE 521
           EG+    +HGD  Q +R + +  F+    P+LVAT VAARGLDI +++ VIN+D+  DI+
Sbjct: 521 EGHNLGLLHGDMDQSERNKVISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDID 580

Query: 522 EYVHRIGRTGRVGNLGLATSFFNEKNMNITKDLLDLLVEAKQEVPSWLENMAYEHHYKGG 581
            + HRIGRTGR G  G+A +    K+ N   DL+  L  A Q V   L ++A ++ +   
Sbjct: 581 THTHRIGRTGRAGEKGVAYTLLTPKDSNFAGDLVRNLEGANQHVSKELLDLAMQNAWFRK 640

Query: 582 SRGR-SKSNRFSGGFGARDYRQSSGSSSSGFGASRGSSS 619
           SR +  K  + + G G   YR+  G  S      RG+++
Sbjct: 641 SRFKGGKGKKLNIGGGGLGYRERPGLGSENM--DRGNNN 677


>gi|55749865 DEAD (Asp-Glu-Ala-Asp) box polypeptide 53 [Homo
           sapiens]
          Length = 631

 Score =  245 bits (625), Expect = 1e-64
 Identities = 142/395 (35%), Positives = 220/395 (55%), Gaps = 18/395 (4%)

Query: 200 RPTPVQKHAIPIIKGKRDLMACAQTGSGKTAAFLLPILSQIYTDGPGEALKAVKENGRYG 259
           +PTP+Q  A PII    DL+  AQTG+GKT ++L+P    I+ D   + +   + NG   
Sbjct: 244 KPTPIQSQAWPIILQGIDLIVVAQTGTGKTLSYLMP--GFIHLDS--QPISREQRNG--- 296

Query: 260 RRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQIRDLERGCHLLV 319
                P  LVL PTRELA+ +  E  K+SY+     C+ YGG +   QI D+ +G  +++
Sbjct: 297 -----PGMLVLTPTRELALHVEAECSKYSYKGLKSICI-YGGRNRNGQIEDISKGVDIII 350

Query: 320 ATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMF 379
           ATPGRL D+     + L    YLV+DEAD+MLDM FEPQIR+I+  D  P    R T+M 
Sbjct: 351 ATPGRLNDLQMNNSVNLRSITYLVIDEADKMLDMEFEPQIRKIL-LDVRPD---RQTVMT 406

Query: 380 SATFPKEIQMLARDFLDEYIFLAVGRVGSTSEN-ITQKVVWVEDLDKRSFLLDILGATGS 438
           SAT+P  ++ LA  +L + + + VG +   + N + Q ++   + +KR+   + +     
Sbjct: 407 SATWPDTVRQLALSYLKDPMIVYVGNLNLVAVNTVKQNIIVTTEKEKRALTQEFVENMSP 466

Query: 439 DSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAV 498
           +   ++FV  K  AD L      +G +  S+HG+  Q D+E A+  F+SG   IL+ T +
Sbjct: 467 NDKVIMFVSQKHIADDLSSDFNIQGISAESLHGNSEQSDQERAVEDFKSGNIKILITTDI 526

Query: 499 AARGLDISNVRHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNEKNMNITKDLLDLL 558
            +RGLD+++V HV N+D P +I+ YVHR+G  GR G  G + +   +++  +  +L+ +L
Sbjct: 527 VSRGLDLNDVTHVYNYDFPRNIDVYVHRVGYIGRTGKTGTSVTLITQRDSKMAGELIKIL 586

Query: 559 VEAKQEVPSWLENMAYEHHYKGGSRGRSKSNRFSG 593
             A Q VP  L  MA ++      R R   +R  G
Sbjct: 587 DRANQSVPEDLVVMAEQYKLNQQKRHRETRSRKPG 621


>gi|188035877 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 [Homo
           sapiens]
          Length = 619

 Score =  230 bits (587), Expect = 3e-60
 Identities = 145/417 (34%), Positives = 229/417 (54%), Gaps = 25/417 (5%)

Query: 177 IENFSDIDMGEIIMGNIELTRYTRPTPVQKHAIPIIKGKRDLMACAQTGSGKTAAFLLPI 236
           I +F    + E++  N++ + Y  PTP+Q   IP+    RD++A A TGSGKTAAFLLP+
Sbjct: 202 IIDFEHCSLPEVLNHNLKKSGYEVPTPIQMQMIPVGLLGRDILASADTGSGKTAAFLLPV 261

Query: 237 LSQIYTDGPGEALKAVKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKF-SYRSRVRP 295
           +           ++A+ E+       + P +L+L PTRELA+QI  +A++  S   R++ 
Sbjct: 262 I-----------MRALFES-------KTPSALILTPTRELAIQIERQAKELMSGLPRMKT 303

Query: 296 CVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGF 355
            ++ GG  +  Q+  L++   +++ATPGRL+D++++  + L   K +V+DEAD ML MGF
Sbjct: 304 VLLVGGLPLPPQLYRLQQHVKVIIATPGRLLDIIKQSSVELCGVKIVVVDEADTMLKMGF 363

Query: 356 EPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQ 415
           + Q+  I+E     P   + T++ SAT P  I+ LA   L   + +  G       N+ Q
Sbjct: 364 QQQVLDILENI---PNDCQ-TILVSATIPTSIEQLASQLLHNPVRIITGEKNLPCANVRQ 419

Query: 416 KVVWVEDLDKRSFLLDILGATGS-DSLTLVFVETKKGADSLEDFLYH-EGYACTSIHGDR 473
            ++WVED  K+  L +IL          LVFV+ K GAD L + +    G    SIH ++
Sbjct: 420 IILWVEDPAKKKKLFEILNDKKLFKPPVLVFVDCKLGADLLSEAVQKITGLKSISIHSEK 479

Query: 474 SQRDREEALHQFRSGKSPILVATAVAARGLDISNVRHVINFDLPSDIEEYVHRIGRTGRV 533
           SQ +R+  L     G   ++V+T V  RGLD+ +VR V+NFD+PS ++EYVH+IGR GR+
Sbjct: 480 SQIERKNILKGLLEGDYEVVVSTGVLGRGLDLISVRLVVNFDMPSSMDEYVHQIGRVGRL 539

Query: 534 GNLGLATSFFNEKNMNITKDLLDLLVEAKQEVPSWLENMAYEHHYKGGSRGRSKSNR 590
           G  G A +F N  +  +  D+   +      +P  L N  Y H  K   + + K  +
Sbjct: 540 GQNGTAITFINNNSKRLFWDIAKRVKPTGSILPPQLLNSPYLHDQKRKEQQKDKQTQ 596


>gi|224593278 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 [Homo
           sapiens]
          Length = 796

 Score =  211 bits (538), Expect = 1e-54
 Identities = 133/383 (34%), Positives = 205/383 (53%), Gaps = 28/383 (7%)

Query: 179 NFSDIDMGEIIMGNIELTRYTRPTPVQKHAIPIIKGKRDLMACAQTGSGKTAAFLLPILS 238
           +F D+++   ++  I    + +PTP+QK  IP+    +D+ ACA TG+GKTAAF LP+L 
Sbjct: 219 SFQDMNLSRPLLKAITAMGFKQPTPIQKACIPVGLLGKDICACAATGTGKTAAFALPVLE 278

Query: 239 QIYTDGPGEALKAVKENGRYGRRKQYPIS--LVLAPTRELAVQIYEEARKFSYRSRVRPC 296
           ++                   + +Q P++  LVL PTREL +Q++   R+ +    +  C
Sbjct: 279 RLIY-----------------KPRQAPVTRVLVLVPTRELGIQVHSVTRQLAQFCNITTC 321

Query: 297 VVYGGADIGQQIRDLERGCHLLVATPGRLVDMMER-GKIGLDFCKYLVLDEADRMLDMGF 355
           +  GG D+  Q   L     +L+ATPGRL+D +       L   + L+LDEADRMLD  F
Sbjct: 322 LAVGGLDVKSQEAALRAAPDILIATPGRLIDHLHNCPSFHLSSIEVLILDEADRMLDEYF 381

Query: 356 EPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQ 415
           E Q++ I+   +      R TM+FSAT   E++ LA   L   + + V      +  + Q
Sbjct: 382 EEQMKEIIRMCSHH----RQTMLFSATMTDEVKDLASVSLKNPVRIFVNSNTDVAPFLRQ 437

Query: 416 KVVWVE---DLDKRSFLLDILGATGSDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGD 472
           + + +    + D+ + +  +L  T +D + L F +TKK A  +   L   G     +HG+
Sbjct: 438 EFIRIRPNREGDREAIVAALLTRTFTDHVML-FTQTKKQAHRMHILLGLMGLQVGELHGN 496

Query: 473 RSQRDREEALHQFRSGKSPILVATAVAARGLDISNVRHVINFDLPSDIEEYVHRIGRTGR 532
            SQ  R EAL +F+  +  ILVAT VAARGLDI  V+ VINF +P+ I+ YVHR+GRT R
Sbjct: 497 LSQTQRLEALRRFKDEQIDILVATDVAARGLDIEGVKTVINFTMPNTIKHYVHRVGRTAR 556

Query: 533 VGNLGLATSFFNEKNMNITKDLL 555
            G  G + S   E    + K+++
Sbjct: 557 AGRAGRSVSLVGEDERKMLKEIV 579


>gi|20149629 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 1
           [Homo sapiens]
          Length = 455

 Score =  210 bits (535), Expect = 3e-54
 Identities = 131/382 (34%), Positives = 207/382 (54%), Gaps = 24/382 (6%)

Query: 178 ENFSDIDMGEIIMGNIELTRYTRPTPVQKHAIPIIKGKRDLMACAQTGSGKTAAFLLPIL 237
           + F D+ + +++    +   +T+PT +Q  AIP+    RD++  A+TGSGKT AF LPIL
Sbjct: 24  KTFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAFALPIL 83

Query: 238 SQIYTDGPGEALKAVKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCV 297
           + +                      Q   +LVL PTRELA QI E+         V+  V
Sbjct: 84  NALL------------------ETPQRLFALVLTPTRELAFQISEQFEALGSSIGVQSAV 125

Query: 298 VYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGK-IGLDFCKYLVLDEADRMLDMGFE 356
           + GG D   Q   L +  H+++ATPGRL+D +E  K   L   KYLV+DEADR+L+M FE
Sbjct: 126 IVGGIDSMSQSLALAKKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRILNMDFE 185

Query: 357 PQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQK 416
            ++ +I++   + P+  R T +FSAT  K++Q L R  L   +  AV     T E + Q 
Sbjct: 186 TEVDKILK---VIPRD-RKTFLFSATMTKKVQKLQRAALKNPVKCAVSSKYQTVEKLQQY 241

Query: 417 VVWVEDLDKRSFLLDILGATGSDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQR 476
            +++    K ++L+ IL     +S  ++F  T          L + G+    +HG  SQ 
Sbjct: 242 YIFIPSKFKDTYLVYILNELAGNSF-MIFCSTCNNTQRTALLLRNLGFTAIPLHGQMSQS 300

Query: 477 DREEALHQFRSGKSPILVATAVAARGLDISNVRHVINFDLPSDIEEYVHRIGRTGRVGNL 536
            R  +L++F++    IL+AT VA+RGLDI +V  V+NFD+P+  ++Y+HR+GRT R G  
Sbjct: 301 KRLGSLNKFKAKARSILLATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRS 360

Query: 537 GLATSFFNEKNMNITKDLLDLL 558
           G A +F  + ++ + + +  L+
Sbjct: 361 GKAITFVTQYDVELFQRIEHLI 382


>gi|7661920 eukaryotic translation initiation factor 4A, isoform 3
           [Homo sapiens]
          Length = 411

 Score =  209 bits (531), Expect = 9e-54
 Identities = 141/414 (34%), Positives = 219/414 (52%), Gaps = 34/414 (8%)

Query: 154 TGINFEKYDDIPVEATGSNCPPHIENFSDIDMGEIIMGNIELTRYTRPTPVQKHAIP-II 212
           T + FE  +++ V  T          F  + + E ++  I    + +P+ +Q+ AI  II
Sbjct: 24  TKVEFETSEEVDVTPT----------FDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQII 73

Query: 213 KGKRDLMACAQTGSGKTAAFLLPILSQIYTDGPGEALKAVKENGRYGRRKQYPISLVLAP 272
           KG RD++A +Q+G+GKTA F + +L  +           V+E            +L+LAP
Sbjct: 74  KG-RDVIAQSQSGTGKTATFSISVLQCLDIQ--------VRETQ----------ALILAP 114

Query: 273 TRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERG 332
           TRELAVQI +          V+     GG ++G+ IR L+ G H++  TPGR+ DM+ R 
Sbjct: 115 TRELAVQIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRRR 174

Query: 333 KIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLAR 392
            +     K LVLDEAD ML+ GF+ QI  +     +PP      ++ SAT P EI  +  
Sbjct: 175 SLRTRAIKMLVLDEADEMLNKGFKEQIYDVYRY--LPP--ATQVVLISATLPHEILEMTN 230

Query: 393 DFLDEYIFLAVGRVGSTSENITQKVVWVEDLDKRSFLLDILGATGSDSLTLVFVETKKGA 452
            F+ + I + V R   T E I Q  V VE  + +   L  L  T + +  ++F  TK+  
Sbjct: 231 KFMTDPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCNTKRKV 290

Query: 453 DSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVRHVI 512
           D L + +    +  +S+HGD  Q++RE  + +FRSG S +L++T V ARGLD+  V  +I
Sbjct: 291 DWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLII 350

Query: 513 NFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNEKNMNITKDLLDLLVEAKQEVP 566
           N+DLP++ E Y+HRIGR+GR G  G+A +F    ++ I +D+         E+P
Sbjct: 351 NYDLPNNRELYIHRIGRSGRYGRKGVAINFVKNDDIRILRDIEQYYSTQIDEMP 404


>gi|38569503 ATP-dependent RNA helicase ROK1 isoform b [Homo
           sapiens]
          Length = 491

 Score =  206 bits (524), Expect = 6e-53
 Identities = 141/440 (32%), Positives = 232/440 (52%), Gaps = 34/440 (7%)

Query: 145 EQELFSGGNTGINFEKYDDI----PVEATGSNCPPHIENFSDID----MGEIIMGNIELT 196
           E +L SG    +  EK + +     +   G++ P  I  F  +D    +   ++ NI   
Sbjct: 16  ESKLTSGKLENLRKEKINFLRNKHKIHVQGTDLPDPIATFQQLDQEYKINSRLLQNILDA 75

Query: 197 RYTRPTPVQKHAIPIIKGKRDLMACAQTGSGKTAAFLLPILSQIYTDGPGEALKAVKENG 256
            +  PTP+Q  AIP++   R+L+A A TGSGKT AF +PIL Q+            K+  
Sbjct: 76  GFQMPTPIQMQAIPVMLHGRELLASAPTGSGKTLAFSIPILMQL------------KQPA 123

Query: 257 RYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQIRDLE-RGC 315
             G R     +L+++PTRELA QI+ E  K S  +  R  +++  A   ++      +  
Sbjct: 124 NKGFR-----ALIISPTRELASQIHRELIKISEGTGFRIHMIHKAAVAAKKFGPKSSKKF 178

Query: 316 HLLVATPGRLVDMMERGKIGLDFC--KYLVLDEADRMLD---MGFEPQIRRIVEQDTMPP 370
            +LV TP RL+ ++++   G+D    ++LV+DE+D++ +    GF  Q+  I    T   
Sbjct: 179 DILVTTPNRLIYLLKQDPPGIDLASVEWLVVDESDKLFEDGKTGFRDQLASIFLACTSHK 238

Query: 371 KGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVVWVEDLDKRSFLL 430
             VR  M FSATF  +++   +  LD  I +++G   S  E + Q++++V     +   +
Sbjct: 239 --VRRAM-FSATFAYDVEQWCKLNLDNVISVSIGARNSAVETVEQELLFVGSETGKLLAM 295

Query: 431 DILGATGSDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKS 490
             L   G +   LVFV++ + A  L   L +EG     IH +R+Q+ R+  +H FR+GK 
Sbjct: 296 RELVKKGFNPPVLVFVQSIERAKELFHELIYEGINVDVIHAERTQQQRDNTVHSFRAGKI 355

Query: 491 PILVATAVAARGLDISNVRHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNEKNMNI 550
            +L+ TA+ ARG+D   V  VIN+D P+   EY+HRIGRTGR GN G A +FF E +  +
Sbjct: 356 WVLICTALLARGIDFKGVNLVINYDFPTSSVEYIHRIGRTGRAGNKGKAITFFTEDDKPL 415

Query: 551 TKDLLDLLVEAKQEVPSWLE 570
            + + +++ +A   VP +++
Sbjct: 416 LRSVANVIQQAGCPVPEYIK 435


>gi|38569505 ATP-dependent RNA helicase ROK1 isoform a [Homo
           sapiens]
          Length = 599

 Score =  206 bits (524), Expect = 6e-53
 Identities = 141/440 (32%), Positives = 232/440 (52%), Gaps = 34/440 (7%)

Query: 145 EQELFSGGNTGINFEKYDDI----PVEATGSNCPPHIENFSDID----MGEIIMGNIELT 196
           E +L SG    +  EK + +     +   G++ P  I  F  +D    +   ++ NI   
Sbjct: 124 ESKLTSGKLENLRKEKINFLRNKHKIHVQGTDLPDPIATFQQLDQEYKINSRLLQNILDA 183

Query: 197 RYTRPTPVQKHAIPIIKGKRDLMACAQTGSGKTAAFLLPILSQIYTDGPGEALKAVKENG 256
            +  PTP+Q  AIP++   R+L+A A TGSGKT AF +PIL Q+            K+  
Sbjct: 184 GFQMPTPIQMQAIPVMLHGRELLASAPTGSGKTLAFSIPILMQL------------KQPA 231

Query: 257 RYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQIRDLE-RGC 315
             G R     +L+++PTRELA QI+ E  K S  +  R  +++  A   ++      +  
Sbjct: 232 NKGFR-----ALIISPTRELASQIHRELIKISEGTGFRIHMIHKAAVAAKKFGPKSSKKF 286

Query: 316 HLLVATPGRLVDMMERGKIGLDFC--KYLVLDEADRMLD---MGFEPQIRRIVEQDTMPP 370
            +LV TP RL+ ++++   G+D    ++LV+DE+D++ +    GF  Q+  I    T   
Sbjct: 287 DILVTTPNRLIYLLKQDPPGIDLASVEWLVVDESDKLFEDGKTGFRDQLASIFLACTSHK 346

Query: 371 KGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVVWVEDLDKRSFLL 430
             VR  M FSATF  +++   +  LD  I +++G   S  E + Q++++V     +   +
Sbjct: 347 --VRRAM-FSATFAYDVEQWCKLNLDNVISVSIGARNSAVETVEQELLFVGSETGKLLAM 403

Query: 431 DILGATGSDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKS 490
             L   G +   LVFV++ + A  L   L +EG     IH +R+Q+ R+  +H FR+GK 
Sbjct: 404 RELVKKGFNPPVLVFVQSIERAKELFHELIYEGINVDVIHAERTQQQRDNTVHSFRAGKI 463

Query: 491 PILVATAVAARGLDISNVRHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNEKNMNI 550
            +L+ TA+ ARG+D   V  VIN+D P+   EY+HRIGRTGR GN G A +FF E +  +
Sbjct: 464 WVLICTALLARGIDFKGVNLVINYDFPTSSVEYIHRIGRTGRAGNKGKAITFFTEDDKPL 523

Query: 551 TKDLLDLLVEAKQEVPSWLE 570
            + + +++ +A   VP +++
Sbjct: 524 LRSVANVIQQAGCPVPEYIK 543


>gi|4503529 eukaryotic translation initiation factor 4A isoform 1
           [Homo sapiens]
          Length = 406

 Score =  202 bits (514), Expect = 8e-52
 Identities = 130/398 (32%), Positives = 216/398 (54%), Gaps = 25/398 (6%)

Query: 171 SNCPPHIENFSDIDMGEIIMGNIELTRYTRPTPVQKHAI-PIIKGKRDLMACAQTGSGKT 229
           SN    +++F D+++ E ++  I    + +P+ +Q+ AI P IKG  D++A AQ+G+GKT
Sbjct: 25  SNWNEIVDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGY-DVIAQAQSGTGKT 83

Query: 230 AAFLLPILSQIYTDGPGEALKAVKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSY 289
           A F + IL QI  D     LKA +             +LVLAPTRELA QI +       
Sbjct: 84  ATFAISILQQIELD-----LKATQ-------------ALVLAPTRELAQQIQKVVMALGD 125

Query: 290 RSRVRPCVVYGGADIGQQIRDLERGC-HLLVATPGRLVDMMERGKIGLDFCKYLVLDEAD 348
                     GG ++  +++ L+    H++V TPGR+ DM+ R  +   + K  VLDEAD
Sbjct: 126 YMGASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEAD 185

Query: 349 RMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGS 408
            ML  GF+ QI  I ++     + V    + SAT P ++  + + F+ + I + V +   
Sbjct: 186 EMLSRGFKDQIYDIFQKLNSNTQVV----LLSATMPSDVLEVTKKFMRDPIRILVKKEEL 241

Query: 409 TSENITQKVVWVEDLDKRSFLLDILGATGSDSLTLVFVETKKGADSLEDFLYHEGYACTS 468
           T E I Q  + VE  + +   L  L  T + +  ++F+ T++  D L + ++   +  ++
Sbjct: 242 TLEGIRQFYINVEREEWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVSA 301

Query: 469 IHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVRHVINFDLPSDIEEYVHRIG 528
           +HGD  Q++R+  + +FRSG S +L+ T + ARG+D+  V  VIN+DLP++ E Y+HRIG
Sbjct: 302 MHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIG 361

Query: 529 RTGRVGNLGLATSFFNEKNMNITKDLLDLLVEAKQEVP 566
           R GR G  G+A +   E++    +D+      + +E+P
Sbjct: 362 RGGRFGRKGVAINMVTEEDKRTLRDIETFYNTSIEEMP 399


>gi|83700235 eukaryotic translation initiation factor 4A2 [Homo
           sapiens]
          Length = 407

 Score =  202 bits (513), Expect = 1e-51
 Identities = 136/422 (32%), Positives = 224/422 (53%), Gaps = 28/422 (6%)

Query: 150 SGGNTGINFEKYDDIPVEATG---SNCPPHIENFSDIDMGEIIMGNIELTRYTRPTPVQK 206
           SGG+   N E      ++  G   SN    ++NF D+++ E ++  I    + +P+ +Q+
Sbjct: 2   SGGSADYNREHGGPEGMDPDGVIESNWNEIVDNFDDMNLKESLLRGIYAYGFEKPSAIQQ 61

Query: 207 HAI-PIIKGKRDLMACAQTGSGKTAAFLLPILSQIYTDGPGEALKAVKENGRYGRRKQYP 265
            AI P IKG  D++A AQ+G+GKTA F + IL Q+  +         KE           
Sbjct: 62  RAIIPCIKGY-DVIAQAQSGTGKTATFAISILQQLEIE--------FKETQ--------- 103

Query: 266 ISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQIRDLERGC-HLLVATPGR 324
            +LVLAPTRELA QI +                 GG ++  +++ L+    H++V TPGR
Sbjct: 104 -ALVLAPTRELAQQIQKVILALGDYMGATCHACIGGTNVRNEMQKLQAEAPHIVVGTPGR 162

Query: 325 LVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFP 384
           + DM+ R  +   + K  VLDEAD ML  GF+ QI  I ++     + V    + SAT P
Sbjct: 163 VFDMLNRRYLSPKWIKMFVLDEADEMLSRGFKDQIYEIFQKLNTSIQVV----LLSATMP 218

Query: 385 KEIQMLARDFLDEYIFLAVGRVGSTSENITQKVVWVEDLDKRSFLLDILGATGSDSLTLV 444
            ++  + + F+ + I + V +   T E I Q  + VE  + +   L  L  T + +  ++
Sbjct: 219 TDVLEVTKKFMRDPIRILVKKEELTLEGIKQFYINVEREEWKLDTLCDLYETLTITQAVI 278

Query: 445 FVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLD 504
           F+ T++  D L + ++   +  +++HGD  Q++R+  + +FRSG S +L+ T + ARG+D
Sbjct: 279 FLNTRRKVDWLTEKMHARDFTVSALHGDMDQKERDVIMREFRSGSSRVLITTDLLARGID 338

Query: 505 ISNVRHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNEKNMNITKDLLDLLVEAKQE 564
           +  V  VIN+DLP++ E Y+HRIGR GR G  G+A +F  E++  I +D+        +E
Sbjct: 339 VQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINFVTEEDKRILRDIETFYNTTVEE 398

Query: 565 VP 566
           +P
Sbjct: 399 MP 400


>gi|50659095 DEAD (Asp-Glu-Ala-Asp) box polypeptide 21 [Homo
           sapiens]
          Length = 783

 Score =  187 bits (476), Expect = 2e-47
 Identities = 143/440 (32%), Positives = 218/440 (49%), Gaps = 44/440 (10%)

Query: 118 ERSGHSRWCDKSVEDDWSKPLP---PSERLEQELFSGGNTGINFEKYDDIPVEATGSNCP 174
           E +G +R     +++ +  P P   PSE   +E         N E   +IPVE       
Sbjct: 138 EMNGETREKSPKLKNGFPHPEPDCNPSEAASEES--------NSEIEQEIPVEQKEGA-- 187

Query: 175 PHIENFSDIDMGEIIMGNIELTRYTRPTPVQKHAIPIIKGKRDLMACAQTGSGKTAAFLL 234
                FS+  + E  +  ++    T   P+Q      +   +DL+A A+TG+GKT +F +
Sbjct: 188 -----FSNFPISEETIKLLKGRGVTFLFPIQAKTFHHVYSGKDLIAQARTGTGKTFSFAI 242

Query: 235 PILSQIYTDGPGEALKAVKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVR 294
           P++ +++    GE      ++ + GR  Q    LVLAPTRELA Q+ ++    + +  V 
Sbjct: 243 PLIEKLH----GEL-----QDRKRGRAPQV---LVLAPTRELANQVSKDFSDITKKLSV- 289

Query: 295 PCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMG 354
               YGG   G Q   +  G  +LV TPGR+ D ++ GK+ L   K++VLDE D+MLDMG
Sbjct: 290 -ACFYGGTPYGGQFERMRNGIDILVGTPGRIKDHIQNGKLDLTKLKHVVLDEVDQMLDMG 348

Query: 355 FEPQIRRIVEQD-TMPPKGVRHTMMFSATFPKEIQMLARDFLD------EYIFLAVGRVG 407
           F  Q+  I+        +    T++FSAT P  +  +A+ ++       + I     +  
Sbjct: 349 FADQVEEILSVAYKKDSEDNPQTLLFSATCPHWVFNVAKKYMKSTYEQVDLIGKKTQKTA 408

Query: 408 STSENITQKVVWVEDLDKRSFLLDILGA-TGSDSLTLVFVETKKGADSLEDFLYHEGYAC 466
            T E++  K  W +   + + + D++   +G    T++F ETKK A  L      +  A 
Sbjct: 409 ITVEHLAIKCHWTQ---RAAVIGDVIRVYSGHQGRTIIFCETKKEAQELSQNSAIKQDA- 464

Query: 467 TSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVRHVINFDLPSDIEEYVHR 526
            S+HGD  Q+ RE  L  FR+G   +LVAT VAARGLDI  V  VI    P D+E Y+HR
Sbjct: 465 QSLHGDIPQKQREITLKGFRNGSFGVLVATNVAARGLDIPEVDLVIQSSPPKDVESYIHR 524

Query: 527 IGRTGRVGNLGLATSFFNEK 546
            GRTGR G  G+   F+  K
Sbjct: 525 SGRTGRAGRTGVCICFYQHK 544


>gi|13129006 nucleolar protein GU2 [Homo sapiens]
          Length = 737

 Score =  182 bits (461), Expect = 1e-45
 Identities = 120/376 (31%), Positives = 196/376 (52%), Gaps = 28/376 (7%)

Query: 180 FSDIDMGEIIMGNIELTRYTRPTPVQKHAI-PIIKGKRDLMACAQTGSGKTAAFLLPILS 238
           FS+  + E  +  ++    T   P+Q     P+ +GK DL+A A+TG+GKT +F +P++ 
Sbjct: 139 FSNFPISEETIKLLKGRGVTYLFPIQVKTFGPVYEGK-DLIAQARTGTGKTFSFAIPLIE 197

Query: 239 QIYTDGPGEALKAVKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVV 298
           ++            + N    ++ + P  LVLAPTRELA Q+ ++ +  + +  V     
Sbjct: 198 RL------------QRNQETIKKSRSPKVLVLAPTRELANQVAKDFKDITRKLSV--ACF 243

Query: 299 YGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQ 358
           YGG     QI  +  G  +LV TPGR+ D ++ G++ L   +++VLDE D+MLD+GF  Q
Sbjct: 244 YGGTSYQSQINHIRNGIDILVGTPGRIKDHLQSGRLDLSKLRHVVLDEVDQMLDLGFAEQ 303

Query: 359 IRRIVEQD-TMPPKGVRHTMMFSATFPKEIQMLARDFLD------EYIFLAVGRVGSTSE 411
           +  I+ +      +    T++FSAT P+ +  +A+ ++       + +     +  +T E
Sbjct: 304 VEDIIHESYKTDSEDNPQTLLFSATCPQWVYKVAKKYMKSRYEQVDLVGKMTQKAATTVE 363

Query: 412 NITQKVVWVEDLDKRSFLLDILGA-TGSDSLTLVFVETKKGADSLEDFLYHEGYACTSIH 470
           ++  +  W +   + + + D+L   +GS+   ++F ETKK    +     H       +H
Sbjct: 364 HLAIQCHWSQ---RPAVIGDVLQVYSGSEGRAIIFCETKKNVTEMA-MNPHIKQNAQCLH 419

Query: 471 GDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVRHVINFDLPSDIEEYVHRIGRT 530
           GD +Q  RE  L  FR G   +LVAT VAARGLDI  V  VI    P D+E Y+HR GRT
Sbjct: 420 GDIAQSQREITLKGFREGSFKVLVATNVAARGLDIPEVDLVIQSSPPQDVESYIHRSGRT 479

Query: 531 GRVGNLGLATSFFNEK 546
           GR G  G+   F+  +
Sbjct: 480 GRAGRTGICICFYQPR 495


>gi|164664518 DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 [Homo
           sapiens]
          Length = 483

 Score =  180 bits (457), Expect = 3e-45
 Identities = 120/393 (30%), Positives = 204/393 (51%), Gaps = 26/393 (6%)

Query: 187 EIIMGNIELTRYTRPTPVQKHAIPIIKGKRDLMACAQTGSGKTAAFLLPILSQIYTDGPG 246
           E++MG  E+  + +P+P+Q+ +IPI    RD++A A+ G+GK+ A+L+P+L         
Sbjct: 106 ELLMGIFEMG-WEKPSPIQEESIPIALSGRDILARAKNGTGKSGAYLIPLL--------- 155

Query: 247 EALKAVKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFS-YRSRVRPCVVYGGADIG 305
           E L   K+N +         ++V+ PTRELA+Q+ +   + S +    +     GG ++ 
Sbjct: 156 ERLDLKKDNIQ---------AMVIVPTRELALQVSQICIQVSKHMGGAKVMATTGGTNLR 206

Query: 306 QQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQ 365
             I  L+   H+++ATPGR++D++++G   +D  + +VLDEAD++L   F   +  I+  
Sbjct: 207 DDIMRLDDTVHVVIATPGRILDLIKKGVAKVDHVQMIVLDEADKLLSQDFVQIMEDIIL- 265

Query: 366 DTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVVWVEDLDK 425
            T+P    R  +++SATFP  +Q      L +   + +     T + +TQ   +V +  K
Sbjct: 266 -TLPKN--RQILLYSATFPLSVQKFMNSHLQKPYEINL-MEELTLKGVTQYYAYVTERQK 321

Query: 426 RSFLLDILGATGSDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQF 485
               L+ L +    + +++F  + +  + L   +   GY+C  IH    Q  R    H F
Sbjct: 322 -VHCLNTLFSRLQINQSIIFCNSSQRVELLAKKISQLGYSCFYIHAKMRQEHRNRVFHDF 380

Query: 486 RSGKSPILVATAVAARGLDISNVRHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNE 545
           R+G    LV T +  RG+DI  V  VINFD P   E Y+HRIGR+GR G+LGLA +    
Sbjct: 381 RNGLCRNLVCTDLFTRGIDIQAVNVVINFDFPKLAETYLHRIGRSGRFGHLGLAINLITY 440

Query: 546 KNMNITKDLLDLLVEAKQEVPSWLENMAYEHHY 578
            +    K + + L    + +PS ++   Y   Y
Sbjct: 441 DDRFNLKSIEEQLGTEIKPIPSNIDKSLYVAEY 473


>gi|51094101 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 2
           [Homo sapiens]
          Length = 881

 Score =  180 bits (456), Expect = 4e-45
 Identities = 116/363 (31%), Positives = 185/363 (50%), Gaps = 21/363 (5%)

Query: 180 FSDIDMGEIIMGNIELTRYTRPTPVQKHAIPIIKGKRDLMACAQTGSGKTAAFLLPILSQ 239
           F  + +   +   I    Y  PTP+Q+  IP+I   +D++A A+TGSGKTA FLLP+  +
Sbjct: 98  FQSMGLSYPVFKGIMKKGYKVPTPIQRKTIPVILDGKDVVAMARTGSGKTACFLLPMFER 157

Query: 240 IYTDGPGEALKAVKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVY 299
           + T       +A                L+L+PTRELA+Q  +  ++    + ++  ++ 
Sbjct: 158 LKTHSAQTGARA----------------LILSPTRELALQTLKFTKELGKFTGLKTALIL 201

Query: 300 GGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQI 359
           GG  +  Q   L     +++ATPGRLV +     + L   +Y+V DEADR+ +MGF  Q+
Sbjct: 202 GGDRMEDQFAALHENPDIIIATPGRLVHVAVEMSLKLQSVEYVVFDEADRLFEMGFAEQL 261

Query: 360 RRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVVW 419
           + I+ +  +P  G   T++FSAT PK +   AR  L E + + +      +E +      
Sbjct: 262 QEIIAR--LP--GGHQTVLFSATLPKLLVEFARAGLTEPVLIRLDVDTKLNEQLKTSFFL 317

Query: 420 VEDLDKRSFLLDIL-GATGSDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDR 478
           V +  K + LL +L         T+VFV TK  A+ L + L  +  +C  I+       R
Sbjct: 318 VREDTKAAVLLHLLHNVVRPQDQTVVFVATKHHAEYLTELLTTQRVSCAHIYSALDPTAR 377

Query: 479 EEALHQFRSGKSPILVATAVAARGLDISNVRHVINFDLPSDIEEYVHRIGRTGRVGNLGL 538
           +  L +F  GK   L+ T +AARGLDI  + +VIN+  P+  + ++HR+GR  R G  G 
Sbjct: 378 KINLAKFTLGKCSTLIVTDLAARGLDIPLLDNVINYSFPAKGKLFLHRVGRVARAGRSGT 437

Query: 539 ATS 541
           A S
Sbjct: 438 AYS 440


>gi|164419743 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 1
           [Homo sapiens]
          Length = 882

 Score =  180 bits (456), Expect = 4e-45
 Identities = 116/363 (31%), Positives = 185/363 (50%), Gaps = 21/363 (5%)

Query: 180 FSDIDMGEIIMGNIELTRYTRPTPVQKHAIPIIKGKRDLMACAQTGSGKTAAFLLPILSQ 239
           F  + +   +   I    Y  PTP+Q+  IP+I   +D++A A+TGSGKTA FLLP+  +
Sbjct: 98  FQSMGLSYPVFKGIMKKGYKVPTPIQRKTIPVILDGKDVVAMARTGSGKTACFLLPMFER 157

Query: 240 IYTDGPGEALKAVKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVY 299
           + T       +A                L+L+PTRELA+Q  +  ++    + ++  ++ 
Sbjct: 158 LKTHSAQTGARA----------------LILSPTRELALQTLKFTKELGKFTGLKTALIL 201

Query: 300 GGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQI 359
           GG  +  Q   L     +++ATPGRLV +     + L   +Y+V DEADR+ +MGF  Q+
Sbjct: 202 GGDRMEDQFAALHENPDIIIATPGRLVHVAVEMSLKLQSVEYVVFDEADRLFEMGFAEQL 261

Query: 360 RRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVVW 419
           + I+ +  +P  G   T++FSAT PK +   AR  L E + + +      +E +      
Sbjct: 262 QEIIAR--LP--GGHQTVLFSATLPKLLVEFARAGLTEPVLIRLDVDTKLNEQLKTSFFL 317

Query: 420 VEDLDKRSFLLDIL-GATGSDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDR 478
           V +  K + LL +L         T+VFV TK  A+ L + L  +  +C  I+       R
Sbjct: 318 VREDTKAAVLLHLLHNVVRPQDQTVVFVATKHHAEYLTELLTTQRVSCAHIYSALDPTAR 377

Query: 479 EEALHQFRSGKSPILVATAVAARGLDISNVRHVINFDLPSDIEEYVHRIGRTGRVGNLGL 538
           +  L +F  GK   L+ T +AARGLDI  + +VIN+  P+  + ++HR+GR  R G  G 
Sbjct: 378 KINLAKFTLGKCSTLIVTDLAARGLDIPLLDNVINYSFPAKGKLFLHRVGRVARAGRSGT 437

Query: 539 ATS 541
           A S
Sbjct: 438 AYS 440


>gi|31542656 DEAD (Asp-Glu-Ala-Asp) box polypeptide 49 [Homo
           sapiens]
          Length = 483

 Score =  178 bits (452), Expect = 1e-44
 Identities = 123/392 (31%), Positives = 198/392 (50%), Gaps = 29/392 (7%)

Query: 180 FSDIDMGEIIMGNIELTRYTRPTPVQKHAIPIIKGKRDLMACAQTGSGKTAAFLLPILSQ 239
           F+++ +   ++         +PTPVQ   IP I   RD + CA+TGSGKTAAF+LPIL +
Sbjct: 4   FAELGLSSWLVEQCRQLGLKQPTPVQLGCIPAILEGRDCLGCAKTGSGKTAAFVLPILQK 63

Query: 240 IYTDGPGEALKAVKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVY 299
           +  D  G                     LVL PTRELA QI E+ R       ++ C++ 
Sbjct: 64  LSEDPYGI------------------FCLVLTPTRELAYQIAEQFRVLGKPLGLKDCIIV 105

Query: 300 GGADIGQQIRDLERGCHLLVATPGRLVDMMERGK-IGLDFCKYLVLDEADRMLDMG---F 355
           GG D+  Q  +L R  H+++ATPGRL D +       +   ++LV+DEADR+L+ G   F
Sbjct: 106 GGMDMVAQALELSRKPHVVIATPGRLADHLRSSNTFSIKKIRFLVMDEADRLLEQGCTDF 165

Query: 356 EPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQ 415
              +  I+    +P +  R T++FSAT    ++ L     ++  F       ST E + Q
Sbjct: 166 TVDLEAILA--AVPAR--RQTLLFSATLTDTLRELQGLATNQPFFWEAQAPVSTVEQLDQ 221

Query: 416 KVVWVEDLDKRSFLLDILGA---TGSDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGD 472
           + + V +  K ++L+ ++        D   ++F  T K    L   L    +   ++H  
Sbjct: 222 RYLLVPEKVKDAYLVHLIQRFQDEHEDWSIIIFTNTCKTCQILCMMLRKFSFPTVALHSM 281

Query: 473 RSQRDREEALHQFRSGKSPILVATAVAARGLDISNVRHVINFDLPSDIEEYVHRIGRTGR 532
             Q++R  AL +F+S    IL+AT VA+RGLDI  V+ VIN + P   + Y+HR+GRT R
Sbjct: 282 MKQKERFAALAKFKSSIYRILIATDVASRGLDIPTVQVVINHNTPGLPKIYIHRVGRTAR 341

Query: 533 VGNLGLATSFFNEKNMNITKDLLDLLVEAKQE 564
            G  G A +   + ++++   + + + +  +E
Sbjct: 342 AGRQGQAITLVTQYDIHLVHAIEEQIKKKLEE 373


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.137    0.410 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,856,949
Number of Sequences: 37866
Number of extensions: 1318511
Number of successful extensions: 11529
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 237
Number of HSP's successfully gapped in prelim test: 166
Number of HSP's that attempted gapping in prelim test: 5573
Number of HSP's gapped (non-prelim): 2941
length of query: 660
length of database: 18,247,518
effective HSP length: 109
effective length of query: 551
effective length of database: 14,120,124
effective search space: 7780188324
effective search space used: 7780188324
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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