BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|169881239 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked [Homo sapiens] (660 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|169881239 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked ... 1349 0.0 gi|13514809 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked [... 1349 0.0 gi|87196351 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3 [Homo... 1241 0.0 gi|209862869 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 3 ... 446 e-125 gi|13518015 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 1 [... 446 e-125 gi|216548263 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 2 ... 446 e-125 gi|4758138 DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 [Homo sapiens] 328 7e-90 gi|38201710 DEAD box polypeptide 17 isoform 1 [Homo sapiens] 325 6e-89 gi|148613856 DEAD box polypeptide 17 isoform 3 [Homo sapiens] 325 8e-89 gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapi... 289 6e-78 gi|21071032 DEAD-box protein abstrakt [Homo sapiens] 288 1e-77 gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo sapi... 277 3e-74 gi|222352149 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 [Homo sap... 272 6e-73 gi|45446747 DEAD box polypeptide 42 protein [Homo sapiens] 268 9e-72 gi|45446743 DEAD box polypeptide 42 protein [Homo sapiens] 268 9e-72 gi|55749865 DEAD (Asp-Glu-Ala-Asp) box polypeptide 53 [Homo sapi... 245 1e-64 gi|188035877 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 [Homo sap... 230 3e-60 gi|224593278 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 [Homo sap... 211 1e-54 gi|20149629 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 1 ... 210 3e-54 gi|7661920 eukaryotic translation initiation factor 4A, isoform ... 209 9e-54 gi|38569503 ATP-dependent RNA helicase ROK1 isoform b [Homo sapi... 206 6e-53 gi|38569505 ATP-dependent RNA helicase ROK1 isoform a [Homo sapi... 206 6e-53 gi|4503529 eukaryotic translation initiation factor 4A isoform 1... 202 8e-52 gi|83700235 eukaryotic translation initiation factor 4A2 [Homo s... 202 1e-51 gi|50659095 DEAD (Asp-Glu-Ala-Asp) box polypeptide 21 [Homo sapi... 187 2e-47 gi|13129006 nucleolar protein GU2 [Homo sapiens] 182 1e-45 gi|164664518 DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 [Homo sapi... 180 3e-45 gi|51094101 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 2 ... 180 4e-45 gi|164419743 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 1... 180 4e-45 gi|31542656 DEAD (Asp-Glu-Ala-Asp) box polypeptide 49 [Homo sapi... 178 1e-44 >gi|169881239 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked [Homo sapiens] Length = 660 Score = 1349 bits (3492), Expect = 0.0 Identities = 660/660 (100%), Positives = 660/660 (100%) Query: 1 MSHVVVKNDPELDQQLANLDLNSEKQSGGASTASKGRYIPPHLRNREASKGFHDKDSSGW 60 MSHVVVKNDPELDQQLANLDLNSEKQSGGASTASKGRYIPPHLRNREASKGFHDKDSSGW Sbjct: 1 MSHVVVKNDPELDQQLANLDLNSEKQSGGASTASKGRYIPPHLRNREASKGFHDKDSSGW 60 Query: 61 SCSKDKDAYSSFGSRDSRGKPGYFSERGSGSRGRFDDRGRSDYDGIGNRERPGFGRFERS 120 SCSKDKDAYSSFGSRDSRGKPGYFSERGSGSRGRFDDRGRSDYDGIGNRERPGFGRFERS Sbjct: 61 SCSKDKDAYSSFGSRDSRGKPGYFSERGSGSRGRFDDRGRSDYDGIGNRERPGFGRFERS 120 Query: 121 GHSRWCDKSVEDDWSKPLPPSERLEQELFSGGNTGINFEKYDDIPVEATGSNCPPHIENF 180 GHSRWCDKSVEDDWSKPLPPSERLEQELFSGGNTGINFEKYDDIPVEATGSNCPPHIENF Sbjct: 121 GHSRWCDKSVEDDWSKPLPPSERLEQELFSGGNTGINFEKYDDIPVEATGSNCPPHIENF 180 Query: 181 SDIDMGEIIMGNIELTRYTRPTPVQKHAIPIIKGKRDLMACAQTGSGKTAAFLLPILSQI 240 SDIDMGEIIMGNIELTRYTRPTPVQKHAIPIIKGKRDLMACAQTGSGKTAAFLLPILSQI Sbjct: 181 SDIDMGEIIMGNIELTRYTRPTPVQKHAIPIIKGKRDLMACAQTGSGKTAAFLLPILSQI 240 Query: 241 YTDGPGEALKAVKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYG 300 YTDGPGEALKAVKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYG Sbjct: 241 YTDGPGEALKAVKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYG 300 Query: 301 GADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIR 360 GADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIR Sbjct: 301 GADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIR 360 Query: 361 RIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVVWV 420 RIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVVWV Sbjct: 361 RIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVVWV 420 Query: 421 EDLDKRSFLLDILGATGSDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREE 480 EDLDKRSFLLDILGATGSDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREE Sbjct: 421 EDLDKRSFLLDILGATGSDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREE 480 Query: 481 ALHQFRSGKSPILVATAVAARGLDISNVRHVINFDLPSDIEEYVHRIGRTGRVGNLGLAT 540 ALHQFRSGKSPILVATAVAARGLDISNVRHVINFDLPSDIEEYVHRIGRTGRVGNLGLAT Sbjct: 481 ALHQFRSGKSPILVATAVAARGLDISNVRHVINFDLPSDIEEYVHRIGRTGRVGNLGLAT 540 Query: 541 SFFNEKNMNITKDLLDLLVEAKQEVPSWLENMAYEHHYKGGSRGRSKSNRFSGGFGARDY 600 SFFNEKNMNITKDLLDLLVEAKQEVPSWLENMAYEHHYKGGSRGRSKSNRFSGGFGARDY Sbjct: 541 SFFNEKNMNITKDLLDLLVEAKQEVPSWLENMAYEHHYKGGSRGRSKSNRFSGGFGARDY 600 Query: 601 RQSSGSSSSGFGASRGSSSRSGGGGYGNSRGFGGGGYGGFYNSDGYGGNYNSQGVDWWGN 660 RQSSGSSSSGFGASRGSSSRSGGGGYGNSRGFGGGGYGGFYNSDGYGGNYNSQGVDWWGN Sbjct: 601 RQSSGSSSSGFGASRGSSSRSGGGGYGNSRGFGGGGYGGFYNSDGYGGNYNSQGVDWWGN 660 >gi|13514809 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked [Homo sapiens] Length = 660 Score = 1349 bits (3492), Expect = 0.0 Identities = 660/660 (100%), Positives = 660/660 (100%) Query: 1 MSHVVVKNDPELDQQLANLDLNSEKQSGGASTASKGRYIPPHLRNREASKGFHDKDSSGW 60 MSHVVVKNDPELDQQLANLDLNSEKQSGGASTASKGRYIPPHLRNREASKGFHDKDSSGW Sbjct: 1 MSHVVVKNDPELDQQLANLDLNSEKQSGGASTASKGRYIPPHLRNREASKGFHDKDSSGW 60 Query: 61 SCSKDKDAYSSFGSRDSRGKPGYFSERGSGSRGRFDDRGRSDYDGIGNRERPGFGRFERS 120 SCSKDKDAYSSFGSRDSRGKPGYFSERGSGSRGRFDDRGRSDYDGIGNRERPGFGRFERS Sbjct: 61 SCSKDKDAYSSFGSRDSRGKPGYFSERGSGSRGRFDDRGRSDYDGIGNRERPGFGRFERS 120 Query: 121 GHSRWCDKSVEDDWSKPLPPSERLEQELFSGGNTGINFEKYDDIPVEATGSNCPPHIENF 180 GHSRWCDKSVEDDWSKPLPPSERLEQELFSGGNTGINFEKYDDIPVEATGSNCPPHIENF Sbjct: 121 GHSRWCDKSVEDDWSKPLPPSERLEQELFSGGNTGINFEKYDDIPVEATGSNCPPHIENF 180 Query: 181 SDIDMGEIIMGNIELTRYTRPTPVQKHAIPIIKGKRDLMACAQTGSGKTAAFLLPILSQI 240 SDIDMGEIIMGNIELTRYTRPTPVQKHAIPIIKGKRDLMACAQTGSGKTAAFLLPILSQI Sbjct: 181 SDIDMGEIIMGNIELTRYTRPTPVQKHAIPIIKGKRDLMACAQTGSGKTAAFLLPILSQI 240 Query: 241 YTDGPGEALKAVKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYG 300 YTDGPGEALKAVKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYG Sbjct: 241 YTDGPGEALKAVKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYG 300 Query: 301 GADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIR 360 GADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIR Sbjct: 301 GADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIR 360 Query: 361 RIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVVWV 420 RIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVVWV Sbjct: 361 RIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVVWV 420 Query: 421 EDLDKRSFLLDILGATGSDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREE 480 EDLDKRSFLLDILGATGSDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREE Sbjct: 421 EDLDKRSFLLDILGATGSDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREE 480 Query: 481 ALHQFRSGKSPILVATAVAARGLDISNVRHVINFDLPSDIEEYVHRIGRTGRVGNLGLAT 540 ALHQFRSGKSPILVATAVAARGLDISNVRHVINFDLPSDIEEYVHRIGRTGRVGNLGLAT Sbjct: 481 ALHQFRSGKSPILVATAVAARGLDISNVRHVINFDLPSDIEEYVHRIGRTGRVGNLGLAT 540 Query: 541 SFFNEKNMNITKDLLDLLVEAKQEVPSWLENMAYEHHYKGGSRGRSKSNRFSGGFGARDY 600 SFFNEKNMNITKDLLDLLVEAKQEVPSWLENMAYEHHYKGGSRGRSKSNRFSGGFGARDY Sbjct: 541 SFFNEKNMNITKDLLDLLVEAKQEVPSWLENMAYEHHYKGGSRGRSKSNRFSGGFGARDY 600 Query: 601 RQSSGSSSSGFGASRGSSSRSGGGGYGNSRGFGGGGYGGFYNSDGYGGNYNSQGVDWWGN 660 RQSSGSSSSGFGASRGSSSRSGGGGYGNSRGFGGGGYGGFYNSDGYGGNYNSQGVDWWGN Sbjct: 601 RQSSGSSSSGFGASRGSSSRSGGGGYGNSRGFGGGGYGGFYNSDGYGGNYNSQGVDWWGN 660 >gi|87196351 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3 [Homo sapiens] Length = 662 Score = 1241 bits (3210), Expect = 0.0 Identities = 608/662 (91%), Positives = 634/662 (95%), Gaps = 2/662 (0%) Query: 1 MSHVVVKNDPELDQQLANLDLNSEKQSGGASTASKGRYIPPHLRNREASKGFHDKDSSGW 60 MSHV V+N LDQQ A LDLNS G STASKGRYIPPHLRNREA+KGF+DKDSSGW Sbjct: 1 MSHVAVENALGLDQQFAGLDLNSSDNQSGGSTASKGRYIPPHLRNREATKGFYDKDSSGW 60 Query: 61 SCSKDKDAYSSFGSR-DSRGKPGYFSERGSGSRGRFDDRGRSDYDGIGNR-ERPGFGRFE 118 S SKDKDAYSSFGSR DSRGK +FS+RGSGSRGRFDDRGRSDYDGIG+R +R GFG+FE Sbjct: 61 SSSKDKDAYSSFGSRSDSRGKSSFFSDRGSGSRGRFDDRGRSDYDGIGSRGDRSGFGKFE 120 Query: 119 RSGHSRWCDKSVEDDWSKPLPPSERLEQELFSGGNTGINFEKYDDIPVEATGSNCPPHIE 178 R G+SRWCDKS EDDWSKPLPPSERLEQELFSGGNTGINFEKYDDIPVEATG+NCPPHIE Sbjct: 121 RGGNSRWCDKSDEDDWSKPLPPSERLEQELFSGGNTGINFEKYDDIPVEATGNNCPPHIE 180 Query: 179 NFSDIDMGEIIMGNIELTRYTRPTPVQKHAIPIIKGKRDLMACAQTGSGKTAAFLLPILS 238 +FSD++MGEIIMGNIELTRYTRPTPVQKHAIPIIK KRDLMACAQTGSGKTAAFLLPILS Sbjct: 181 SFSDVEMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPILS 240 Query: 239 QIYTDGPGEALKAVKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVV 298 QIY+DGPGEAL+A+KENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVV Sbjct: 241 QIYSDGPGEALRAMKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVV 300 Query: 299 YGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQ 358 YGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQ Sbjct: 301 YGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQ 360 Query: 359 IRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVV 418 IRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVV Sbjct: 361 IRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVV 420 Query: 419 WVEDLDKRSFLLDILGATGSDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDR 478 WVE+ DKRSFLLD+L ATG DSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDR Sbjct: 421 WVEESDKRSFLLDLLNATGKDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDR 480 Query: 479 EEALHQFRSGKSPILVATAVAARGLDISNVRHVINFDLPSDIEEYVHRIGRTGRVGNLGL 538 EEALHQFRSGKSPILVATAVAARGLDISNV+HVINFDLPSDIEEYVHRIGRTGRVGNLGL Sbjct: 481 EEALHQFRSGKSPILVATAVAARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGL 540 Query: 539 ATSFFNEKNMNITKDLLDLLVEAKQEVPSWLENMAYEHHYKGGSRGRSKSNRFSGGFGAR 598 ATSFFNE+N+NITKDLLDLLVEAKQEVPSWLENMAYEHHYKG SRGRSKS+RFSGGFGAR Sbjct: 541 ATSFFNERNINITKDLLDLLVEAKQEVPSWLENMAYEHHYKGSSRGRSKSSRFSGGFGAR 600 Query: 599 DYRQSSGSSSSGFGASRGSSSRSGGGGYGNSRGFGGGGYGGFYNSDGYGGNYNSQGVDWW 658 DYRQSSG+SSS F +SR SSSRSGGGG+G+SRGFGGGGYGGFYNSDGYGGNYNSQGVDWW Sbjct: 601 DYRQSSGASSSSFSSSRASSSRSGGGGHGSSRGFGGGGYGGFYNSDGYGGNYNSQGVDWW 660 Query: 659 GN 660 GN Sbjct: 661 GN 662 >gi|209862869 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 3 [Homo sapiens] Length = 724 Score = 446 bits (1147), Expect = e-125 Identities = 258/539 (47%), Positives = 347/539 (64%), Gaps = 33/539 (6%) Query: 85 SERGSGSRGRFDDRGRSDYDGIGNRERPGFGR----FERSGHSRWCDKSVEDDWSKPLPP 140 S GSGS R Y G+ G G+ E G + + + P PP Sbjct: 200 SRSGSGSE-------RGGYKGLNEEVITGSGKNSWKSEAEGGESSDTQGPKVTYIPPPPP 252 Query: 141 SERLEQELFSGGNTGINFEKYDDIPVEATGSNCPPHIENFSDIDMGEIIMGNIELTRYTR 200 + E +F+ TGINF+KYD I VE +G + PP I F + ++ + + NI YT+ Sbjct: 253 ED--EDSIFAHYQTGINFDKYDTILVEVSGHDAPPAILTFEEANLCQTLNNNIAKAGYTK 310 Query: 201 PTPVQKHAIPIIKGKRDLMACAQTGSGKTAAFLLPILSQIYTDG-PGEALKAVKENGRYG 259 TPVQK++IPII RDLMACAQTGSGKTAAFLLPIL+ + DG K ++E Sbjct: 311 LTPVQKYSIPIILAGRDLMACAQTGSGKTAAFLLPILAHMMHDGITASRFKELQE----- 365 Query: 260 RRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQIRDLERGCHLLV 319 P +++APTREL QIY EARKFS+ + VR V+YGG +G IR + +GC++L Sbjct: 366 -----PECIIVAPTRELVNQIYLEARKFSFGTCVRAVVIYGGTQLGHSIRQIVQGCNILC 420 Query: 320 ATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMF 379 ATPGRL+D++ + KIGL KYLVLDEADRMLDMGF P++++++ MP K R T+MF Sbjct: 421 ATPGRLMDIIGKEKIGLKQIKYLVLDEADRMLDMGFGPEMKKLISCPGMPSKEQRQTLMF 480 Query: 380 SATFPKEIQMLARDFL-DEYIFLAVGRVGSTSENITQKVVWVEDLDKRSFLLDILGATGS 438 SATFP+EIQ LA +FL Y+F+AVG+VG ++ Q V+ V KR L++IL G Sbjct: 481 SATFPEEIQRLAAEFLKSNYLFVAVGQVGGACRDVQQTVLQVGQFSKREKLVEILRNIG- 539 Query: 439 DSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAV 498 D T+VFVETKK AD + FL E + TSIHGDR QR+RE+AL FR GK P+LVAT+V Sbjct: 540 DERTMVFVETKKKADFIATFLCQEKISTTSIHGDREQREREQALGDFRFGKCPVLVATSV 599 Query: 499 AARGLDISNVRHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFN-EKNMNITKDLLDL 557 AARGLDI NV+HVINFDLPS I+EYVHRIGRTGR GN G A SFF+ E + ++ + L+ + Sbjct: 600 AARGLDIENVQHVINFDLPSTIDEYVHRIGRTGRCGNTGRAISFFDLESDNHLAQPLVKV 659 Query: 558 LVEAKQEVPSWLENMAYEHHYKGGSRGRSKSNRFSGGFGARDYRQSSGS-SSSGFGASR 615 L +A+Q+VP+WLE +A+ + G S G ++ N F+ + D R+ + +++GF +S+ Sbjct: 660 LTDAQQDVPAWLEEIAFSTYIPGFS-GSTRGNVFA----SVDTRKGKSTLNTAGFSSSQ 713 Score = 30.0 bits (66), Expect = 7.1 Identities = 23/68 (33%), Positives = 32/68 (47%), Gaps = 10/68 (14%) Query: 575 EHHYKGG-SRGRSKSNRFSGGFGARDYRQSSGSSSSGFGASRGSSSRSGGGGYGNSRGFG 633 +H K G + GR+ NR +G RD + G GFG + +R G+ NSR F Sbjct: 52 DHFMKSGFASGRNFGNRDAGECNKRDNTSTMG----GFGVGKSFGNR----GFSNSR-FE 102 Query: 634 GGGYGGFY 641 G GF+ Sbjct: 103 DGDSSGFW 110 Score = 30.0 bits (66), Expect = 7.1 Identities = 24/68 (35%), Positives = 29/68 (42%), Gaps = 4/68 (5%) Query: 581 GSRGRSKSNRFSGGFGARDYRQSSGSSSSGFGASRGSSSRSGGGGYGNSRGFG---GGGY 637 G+RG S S RF G + +R+SS +RG S R G NS G GG Sbjct: 92 GNRGFSNS-RFEDGDSSGFWRESSNDCEDNPTRNRGFSKRGGYRDGNNSEASGPYRRGGR 150 Query: 638 GGFYNSDG 645 G F G Sbjct: 151 GSFRGCRG 158 >gi|13518015 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 1 [Homo sapiens] Length = 724 Score = 446 bits (1147), Expect = e-125 Identities = 258/539 (47%), Positives = 347/539 (64%), Gaps = 33/539 (6%) Query: 85 SERGSGSRGRFDDRGRSDYDGIGNRERPGFGR----FERSGHSRWCDKSVEDDWSKPLPP 140 S GSGS R Y G+ G G+ E G + + + P PP Sbjct: 200 SRSGSGSE-------RGGYKGLNEEVITGSGKNSWKSEAEGGESSDTQGPKVTYIPPPPP 252 Query: 141 SERLEQELFSGGNTGINFEKYDDIPVEATGSNCPPHIENFSDIDMGEIIMGNIELTRYTR 200 + E +F+ TGINF+KYD I VE +G + PP I F + ++ + + NI YT+ Sbjct: 253 ED--EDSIFAHYQTGINFDKYDTILVEVSGHDAPPAILTFEEANLCQTLNNNIAKAGYTK 310 Query: 201 PTPVQKHAIPIIKGKRDLMACAQTGSGKTAAFLLPILSQIYTDG-PGEALKAVKENGRYG 259 TPVQK++IPII RDLMACAQTGSGKTAAFLLPIL+ + DG K ++E Sbjct: 311 LTPVQKYSIPIILAGRDLMACAQTGSGKTAAFLLPILAHMMHDGITASRFKELQE----- 365 Query: 260 RRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQIRDLERGCHLLV 319 P +++APTREL QIY EARKFS+ + VR V+YGG +G IR + +GC++L Sbjct: 366 -----PECIIVAPTRELVNQIYLEARKFSFGTCVRAVVIYGGTQLGHSIRQIVQGCNILC 420 Query: 320 ATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMF 379 ATPGRL+D++ + KIGL KYLVLDEADRMLDMGF P++++++ MP K R T+MF Sbjct: 421 ATPGRLMDIIGKEKIGLKQIKYLVLDEADRMLDMGFGPEMKKLISCPGMPSKEQRQTLMF 480 Query: 380 SATFPKEIQMLARDFL-DEYIFLAVGRVGSTSENITQKVVWVEDLDKRSFLLDILGATGS 438 SATFP+EIQ LA +FL Y+F+AVG+VG ++ Q V+ V KR L++IL G Sbjct: 481 SATFPEEIQRLAAEFLKSNYLFVAVGQVGGACRDVQQTVLQVGQFSKREKLVEILRNIG- 539 Query: 439 DSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAV 498 D T+VFVETKK AD + FL E + TSIHGDR QR+RE+AL FR GK P+LVAT+V Sbjct: 540 DERTMVFVETKKKADFIATFLCQEKISTTSIHGDREQREREQALGDFRFGKCPVLVATSV 599 Query: 499 AARGLDISNVRHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFN-EKNMNITKDLLDL 557 AARGLDI NV+HVINFDLPS I+EYVHRIGRTGR GN G A SFF+ E + ++ + L+ + Sbjct: 600 AARGLDIENVQHVINFDLPSTIDEYVHRIGRTGRCGNTGRAISFFDLESDNHLAQPLVKV 659 Query: 558 LVEAKQEVPSWLENMAYEHHYKGGSRGRSKSNRFSGGFGARDYRQSSGS-SSSGFGASR 615 L +A+Q+VP+WLE +A+ + G S G ++ N F+ + D R+ + +++GF +S+ Sbjct: 660 LTDAQQDVPAWLEEIAFSTYIPGFS-GSTRGNVFA----SVDTRKGKSTLNTAGFSSSQ 713 Score = 30.0 bits (66), Expect = 7.1 Identities = 23/68 (33%), Positives = 32/68 (47%), Gaps = 10/68 (14%) Query: 575 EHHYKGG-SRGRSKSNRFSGGFGARDYRQSSGSSSSGFGASRGSSSRSGGGGYGNSRGFG 633 +H K G + GR+ NR +G RD + G GFG + +R G+ NSR F Sbjct: 52 DHFMKSGFASGRNFGNRDAGECNKRDNTSTMG----GFGVGKSFGNR----GFSNSR-FE 102 Query: 634 GGGYGGFY 641 G GF+ Sbjct: 103 DGDSSGFW 110 Score = 30.0 bits (66), Expect = 7.1 Identities = 24/68 (35%), Positives = 29/68 (42%), Gaps = 4/68 (5%) Query: 581 GSRGRSKSNRFSGGFGARDYRQSSGSSSSGFGASRGSSSRSGGGGYGNSRGFG---GGGY 637 G+RG S S RF G + +R+SS +RG S R G NS G GG Sbjct: 92 GNRGFSNS-RFEDGDSSGFWRESSNDCEDNPTRNRGFSKRGGYRDGNNSEASGPYRRGGR 150 Query: 638 GGFYNSDG 645 G F G Sbjct: 151 GSFRGCRG 158 >gi|216548263 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 2 [Homo sapiens] Length = 690 Score = 446 bits (1147), Expect = e-125 Identities = 258/539 (47%), Positives = 347/539 (64%), Gaps = 33/539 (6%) Query: 85 SERGSGSRGRFDDRGRSDYDGIGNRERPGFGR----FERSGHSRWCDKSVEDDWSKPLPP 140 S GSGS R Y G+ G G+ E G + + + P PP Sbjct: 166 SRSGSGSE-------RGGYKGLNEEVITGSGKNSWKSEAEGGESSDTQGPKVTYIPPPPP 218 Query: 141 SERLEQELFSGGNTGINFEKYDDIPVEATGSNCPPHIENFSDIDMGEIIMGNIELTRYTR 200 + E +F+ TGINF+KYD I VE +G + PP I F + ++ + + NI YT+ Sbjct: 219 ED--EDSIFAHYQTGINFDKYDTILVEVSGHDAPPAILTFEEANLCQTLNNNIAKAGYTK 276 Query: 201 PTPVQKHAIPIIKGKRDLMACAQTGSGKTAAFLLPILSQIYTDG-PGEALKAVKENGRYG 259 TPVQK++IPII RDLMACAQTGSGKTAAFLLPIL+ + DG K ++E Sbjct: 277 LTPVQKYSIPIILAGRDLMACAQTGSGKTAAFLLPILAHMMHDGITASRFKELQE----- 331 Query: 260 RRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQIRDLERGCHLLV 319 P +++APTREL QIY EARKFS+ + VR V+YGG +G IR + +GC++L Sbjct: 332 -----PECIIVAPTRELVNQIYLEARKFSFGTCVRAVVIYGGTQLGHSIRQIVQGCNILC 386 Query: 320 ATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMF 379 ATPGRL+D++ + KIGL KYLVLDEADRMLDMGF P++++++ MP K R T+MF Sbjct: 387 ATPGRLMDIIGKEKIGLKQIKYLVLDEADRMLDMGFGPEMKKLISCPGMPSKEQRQTLMF 446 Query: 380 SATFPKEIQMLARDFL-DEYIFLAVGRVGSTSENITQKVVWVEDLDKRSFLLDILGATGS 438 SATFP+EIQ LA +FL Y+F+AVG+VG ++ Q V+ V KR L++IL G Sbjct: 447 SATFPEEIQRLAAEFLKSNYLFVAVGQVGGACRDVQQTVLQVGQFSKREKLVEILRNIG- 505 Query: 439 DSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAV 498 D T+VFVETKK AD + FL E + TSIHGDR QR+RE+AL FR GK P+LVAT+V Sbjct: 506 DERTMVFVETKKKADFIATFLCQEKISTTSIHGDREQREREQALGDFRFGKCPVLVATSV 565 Query: 499 AARGLDISNVRHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFN-EKNMNITKDLLDL 557 AARGLDI NV+HVINFDLPS I+EYVHRIGRTGR GN G A SFF+ E + ++ + L+ + Sbjct: 566 AARGLDIENVQHVINFDLPSTIDEYVHRIGRTGRCGNTGRAISFFDLESDNHLAQPLVKV 625 Query: 558 LVEAKQEVPSWLENMAYEHHYKGGSRGRSKSNRFSGGFGARDYRQSSGS-SSSGFGASR 615 L +A+Q+VP+WLE +A+ + G S G ++ N F+ + D R+ + +++GF +S+ Sbjct: 626 LTDAQQDVPAWLEEIAFSTYIPGFS-GSTRGNVFA----SVDTRKGKSTLNTAGFSSSQ 679 Score = 30.0 bits (66), Expect = 7.1 Identities = 23/68 (33%), Positives = 32/68 (47%), Gaps = 10/68 (14%) Query: 575 EHHYKGG-SRGRSKSNRFSGGFGARDYRQSSGSSSSGFGASRGSSSRSGGGGYGNSRGFG 633 +H K G + GR+ NR +G RD + G GFG + +R G+ NSR F Sbjct: 52 DHFMKSGFASGRNFGNRDAGECNKRDNTSTMG----GFGVGKSFGNR----GFSNSR-FE 102 Query: 634 GGGYGGFY 641 G GF+ Sbjct: 103 DGDSSGFW 110 >gi|4758138 DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 [Homo sapiens] Length = 614 Score = 328 bits (842), Expect = 7e-90 Identities = 223/589 (37%), Positives = 313/589 (53%), Gaps = 52/589 (8%) Query: 82 GYFSERGSGSRGRFDDRGRSDYDGIGNRERPGFGR-FERSGHSRWCDKSVEDDWS-KPLP 139 GY S+R RGR DRG G+R P G+ F G +K V+ W+ LP Sbjct: 3 GYSSDR---DRGR--DRGFGAPRFGGSRAGPLSGKKFGNPG-----EKLVKKKWNLDELP 52 Query: 140 PSER--LEQELFSGGNTGINFEKYD-DIPVEATGSNCPPHIENFSDIDMGEIIMGNIELT 196 E+ ++ T E Y + G NCP + NF + + +M I Sbjct: 53 KFEKNFYQEHPDLARRTAQEVETYRRSKEITVRGHNCPKPVLNFYEANFPANVMDVIARQ 112 Query: 197 RYTRPTPVQKHAIPIIKGKRDLMACAQTGSGKTAAFLLPILSQIYTDGPGEALKAVKENG 256 +T PT +Q P+ D++ AQTGSGKT ++LLP + I + Sbjct: 113 NFTEPTAIQAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAIVHI-------------NHQ 159 Query: 257 RYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQIRDLERGCH 316 + R PI LVLAPTRELA Q+ + A ++ R++ +YGGA G QIRDLERG Sbjct: 160 PFLERGDGPICLVLAPTRELAQQVQQVAAEYCRACRLKSTCIYGGAPKGPQIRDLERGVE 219 Query: 317 LLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHT 376 + +ATPGRL+D +E GK L YLVLDEADRMLDMGFEPQIR+IV+Q + R T Sbjct: 220 ICIATPGRLIDFLECGKTNLRRTTYLVLDEADRMLDMGFEPQIRKIVDQI----RPDRQT 275 Query: 377 MMFSATFPKEIQMLARDFLDEYIFLAVGRVG-STSENITQKVVWVEDLDKRSFLLDILGA 435 +M+SAT+PKE++ LA DFL +YI + +G + S + NI Q V D++K L+ ++ Sbjct: 276 LMWSATWPKEVRQLAEDFLKDYIHINIGALELSANHNILQIVDVCHDVEKDEKLIRLMEE 335 Query: 436 TGSD--SLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPIL 493 S+ + T+VFVETK+ D L + +G+ IHGD+SQ++R+ L++F+ GK+PIL Sbjct: 336 IMSEKENKTIVFVETKRRCDELTRKMRRDGWPAMGIHGDKSQQERDWVLNEFKHGKAPIL 395 Query: 494 VATAVAARGLDISNVRHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNEKNMNITKD 553 +AT VA+RGLD+ +V+ VIN+D P+ E+Y+HRIGRT R G A +FF N+ D Sbjct: 396 IATDVASRGLDVEDVKFVINYDYPNSSEDYIHRIGRTARSTKTGTAYTFFTPNNIKQVSD 455 Query: 554 LLDLLVEAKQEVPSWLENMAYEHHYKGGSRGRSKSNRFSGGFGARDYRQS--SGSSSSGF 611 L+ +L EA Q + L + E G SRGR G +D R+ S GF Sbjct: 456 LISVLREANQAINPKLLQLV-EDRGSGRSRGRG---------GMKDDRRDRYSAGKRGGF 505 Query: 612 GASRGSSSRSGGGGYGNSRGFGGGGYGGFYNSDGY-----GGNYNSQGV 655 R + G R FG G Y++ Y G N+ S G+ Sbjct: 506 NTFRDRENYDRGYSSLLKRDFGAKTQNGVYSAANYTNGSFGSNFVSAGI 554 >gi|38201710 DEAD box polypeptide 17 isoform 1 [Homo sapiens] Length = 729 Score = 325 bits (834), Expect = 6e-89 Identities = 202/508 (39%), Positives = 280/508 (55%), Gaps = 41/508 (8%) Query: 170 GSNCPPHIENFSDIDMGEIIMGNIELTRYTRPTPVQKHAIPIIKGKRDLMACAQTGSGKT 229 G CP + F + + +M + +T PTP+Q P+ RD++ AQTGSGKT Sbjct: 163 GDVCPKPVFAFHHANFPQYVMDVLMDQHFTEPTPIQCQGFPLALSGRDMVGIAQTGSGKT 222 Query: 230 AAFLLPILSQIYTDGPGEALKAVKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSY 289 A+LLP + I + Y R PI LVLAPTRELA Q+ + A + Sbjct: 223 LAYLLPAIVHI-------------NHQPYLERGDGPICLVLAPTRELAQQVQQVADDYGK 269 Query: 290 RSRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADR 349 SR++ +YGGA G QIRDLERG + +ATPGRL+D +E GK L C YLVLDEADR Sbjct: 270 CSRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLESGKTNLRRCTYLVLDEADR 329 Query: 350 MLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVG-S 408 MLDMGFEPQIR+IV+Q + R T+M+SAT+PKE++ LA DFL +Y + VG + S Sbjct: 330 MLDMGFEPQIRKIVDQI----RPDRQTLMWSATWPKEVRQLAEDFLRDYTQINVGNLELS 385 Query: 409 TSENITQKVVWVEDLDKRSFLLDILGA--TGSDSLTLVFVETKKGADSLEDFLYHEGYAC 466 + NI Q V + +K L+ ++ ++ T++FVETK+ D L + +G+ Sbjct: 386 ANHNILQIVDVCMESEKDHKLIQLMEEIMAEKENKTIIFVETKRRCDDLTRRMRRDGWPA 445 Query: 467 TSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVRHVINFDLPSDIEEYVHR 526 IHGD+SQ +R+ L++FRSGK+PIL+AT VA+RGLD+ +V+ VIN+D P+ E+YVHR Sbjct: 446 MCIHGDKSQPERDWVLNEFRSGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYVHR 505 Query: 527 IGRTGRVGNLGLATSFFNEKNMNITKDLLDLLVEAKQEVPSWLENMAYEHHYKGGSRGRS 586 IGRT R N G A +FF N+ ++L+ +L EA Q + L + GG GRS Sbjct: 506 IGRTARSTNKGTAYTFFTPGNLKQARELIKVLEEANQAINPKLMQLVDHRGGGGGGGGRS 565 Query: 587 KSNRFSGGFGAR-------DYR----QSSGSSSSGFGASRGSSSRSG---GGGYGNSRGF 632 + S D R + G S R + R+G G GYG+ Sbjct: 566 RYRTTSSANNPNLMYQDECDRRLRGVKDGGRRDSASYRDRSETDRAGYANGSGYGSPNSA 625 Query: 633 GGGGYG------GFYNSDGYG-GNYNSQ 653 G G G Y + YG +Y +Q Sbjct: 626 FGAQAGQYTYGQGTYGAAAYGTSSYTAQ 653 >gi|148613856 DEAD box polypeptide 17 isoform 3 [Homo sapiens] Length = 731 Score = 325 bits (833), Expect = 8e-89 Identities = 200/511 (39%), Positives = 282/511 (55%), Gaps = 45/511 (8%) Query: 170 GSNCPPHIENFSDIDMGEIIMGNIELTRYTRPTPVQKHAIPIIKGKRDLMACAQTGSGKT 229 G CP + F + + +M + +T PTP+Q P+ RD++ AQTGSGKT Sbjct: 163 GDVCPKPVFAFHHANFPQYVMDVLMDQHFTEPTPIQCQGFPLALSGRDMVGIAQTGSGKT 222 Query: 230 AAFLLPILSQIYTDGPGEALKAVKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSY 289 A+LLP + I + Y R PI LVLAPTRELA Q+ + A + Sbjct: 223 LAYLLPAIVHI-------------NHQPYLERGDGPICLVLAPTRELAQQVQQVADDYGK 269 Query: 290 RSRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADR 349 SR++ +YGGA G QIRDLERG + +ATPGRL+D +E GK L C YLVLDEADR Sbjct: 270 CSRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLESGKTNLRRCTYLVLDEADR 329 Query: 350 MLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVG-S 408 MLDMGFEPQIR+IV+Q + R T+M+SAT+PKE++ LA DFL +Y + VG + S Sbjct: 330 MLDMGFEPQIRKIVDQ----IRPDRQTLMWSATWPKEVRQLAEDFLRDYTQINVGNLELS 385 Query: 409 TSENITQKVVWVEDLDKRSFLLDILG--ATGSDSLTLVFVETKKGADSLEDFLYHEGYAC 466 + NI Q V + +K L+ ++ ++ T++FVETK+ D L + +G+ Sbjct: 386 ANHNILQIVDVCMESEKDHKLIQLMEEIMAEKENKTIIFVETKRRCDDLTRRMRRDGWPA 445 Query: 467 TSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVRHVINFDLPSDIEEYVHR 526 IHGD+SQ +R+ L++FRSGK+PIL+AT VA+RGLD+ +V+ VIN+D P+ E+YVHR Sbjct: 446 MCIHGDKSQPERDWVLNEFRSGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYVHR 505 Query: 527 IGRTGRVGNLGLATSFFNEKNMNITKDLLDLLVEAKQEVPSWLENMAYEHHYKGGSRGRS 586 IGRT R N G A +FF N+ ++L+ +L EA Q + L + +H GG G+ Sbjct: 506 IGRTARSTNKGTAYTFFTPGNLKQARELIKVLEEANQAINPKLMQLV-DHRGGGGGGGKG 564 Query: 587 KSNRFSGGFGARDYR--------------QSSGSSSSGFGASRGSSSRSG---GGGYGNS 629 +R+ A + + G S R + R+G G GYG+ Sbjct: 565 GRSRYRTTSSANNPNLMYQDECDRRLRGVKDGGRRDSASYRDRSETDRAGYANGSGYGSP 624 Query: 630 RGFGGGGYG------GFYNSDGYG-GNYNSQ 653 G G G Y + YG +Y +Q Sbjct: 625 NSAFGAQAGQYTYGQGTYGAAAYGTSSYTAQ 655 >gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapiens] Length = 1031 Score = 289 bits (739), Expect = 6e-78 Identities = 170/458 (37%), Positives = 259/458 (56%), Gaps = 22/458 (4%) Query: 147 ELFSGGNTGINFEKYDDIPVEATGSNCPPHIENFSDIDMGEIIMGNIELTRYTRPTPVQK 206 EL +N + + + G CP I+++ + I+ +++ Y +PTP+Q Sbjct: 341 ELAKMSQEEVNVFRLEMEGITVKGKGCPKPIKSWVQCGISMKILNSLKKHGYEKPTPIQT 400 Query: 207 HAIPIIKGKRDLMACAQTGSGKTAAFLLPILSQIYTDGPGEALKAVKENGRYGRRKQYPI 266 AIP I RDL+ A+TGSGKT AFLLP+ I ++++E + PI Sbjct: 401 QAIPAIMSGRDLIGIAKTGSGKTIAFLLPMFRHIMDQ------RSLEEG-------EGPI 447 Query: 267 SLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLV 326 ++++ PTRELA+QI +E +KFS +R VYGG I +QI +L+RG ++V TPGR++ Sbjct: 448 AVIMTPTRELALQITKECKKFSKTLGLRVVCVYGGTGISEQIAELKRGAEIIVCTPGRMI 507 Query: 327 DMM--ERGKI-GLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATF 383 DM+ G++ L Y+VLDEADRM DMGFEPQ+ RIV D + P R T+MFSATF Sbjct: 508 DMLAANSGRVTNLRRVTYVVLDEADRMFDMGFEPQVMRIV--DNVRPD--RQTVMFSATF 563 Query: 384 PKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVVWVEDLDKRSFLLDILGATGSDSLTL 443 P+ ++ LAR L + I + VG ++ Q+V+ +E+ K LL++LG + Sbjct: 564 PRAMEALARRILSKPIEVQVGGRSVVCSDVEQQVIVIEEEKKFLKLLELLGHYQESGSVI 623 Query: 444 VFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGL 503 +FV+ ++ AD L L Y C S+HG Q DR+ ++ F++G +LVAT+VAARGL Sbjct: 624 IFVDKQEHADGLLKDLMRASYPCMSLHGGIDQYDRDSIINDFKNGTCKLLVATSVAARGL 683 Query: 504 DISNVRHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNEKNMNITKDLLDLLVEAKQ 563 D+ ++ V+N+ P+ E+YVHR GRTGR GN G A +F E D++ L + Sbjct: 684 DVKHLILVVNYSCPNHYEDYVHRAGRTGRAGNKGYAYTFITEDQARYAGDIIKALELSGT 743 Query: 564 EVPSWLENMAYEHHYKGGSRGRSKSNRFSGGFGARDYR 601 VP LE + + +K + K + S GF + ++ Sbjct: 744 AVPPDLEKLWSD--FKDQQKAEGKIIKKSSGFSGKGFK 779 >gi|21071032 DEAD-box protein abstrakt [Homo sapiens] Length = 622 Score = 288 bits (736), Expect = 1e-77 Identities = 169/439 (38%), Positives = 252/439 (57%), Gaps = 30/439 (6%) Query: 170 GSNCPPHIENFSDIDMGEIIMGNIELTRYTRPTPVQKHAIPIIKGKRDLMACAQTGSGKT 229 G PP I++F ++ I+ ++ PTP+Q IP I RD++ A TGSGKT Sbjct: 173 GDGIPPPIKSFKEMKFPAAILRGLKKKGIHHPTPIQIQGIPTILSGRDMIGIAFTGSGKT 232 Query: 230 AAFLLPILSQIYTDGPGEALKAVKENGRYGRRKQYPISLVLAPTRELA------VQIYEE 283 F LP++ ++ + L K G YG L++ P+RELA ++ Y Sbjct: 233 LVFTLPVI--MFCLEQEKRLPFSKREGPYG--------LIICPSRELARQTHGILEYYCR 282 Query: 284 ARKFSYRSRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLV 343 + +R + GG + +Q+ + G H++VATPGRL+D++++ + LD C+YL Sbjct: 283 LLQEDSSPLLRCALCIGGMSVKEQMETIRHGVHMMVATPGRLMDLLQKKMVSLDICRYLA 342 Query: 344 LDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAV 403 LDEADRM+DMGFE IR I KG R T++FSAT PK+IQ A+ L + + + V Sbjct: 343 LDEADRMIDMGFEGDIRTIFSYF----KGQRQTLLFSATMPKKIQNFAKSALVKPVTINV 398 Query: 404 GRVGSTSENITQKVVWVEDLDKRSFLLDILGATGSDSLTLVFVETKKGADSLEDFLYHEG 463 GR G+ S ++ Q+V +V++ K +LL+ L T L+F E K D++ ++L +G Sbjct: 399 GRAGAASLDVIQEVEYVKEEAKMVYLLECLQKTPPP--VLIFAEKKADVDAIHEYLLLKG 456 Query: 464 YACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVRHVINFDLPSDIEEY 523 +IHG + Q +R +A+ FR GK +LVAT VA++GLD ++HVIN+D+P +IE Y Sbjct: 457 VEAVAIHGGKDQEERTKAIEAFREGKKDVLVATDVASKGLDFPAIQHVINYDMPEEIENY 516 Query: 524 VHRIGRTGRVGNLGLATSFFNEK-NMNITKDLLDLLVEAKQEVPSWLENMAYEHHYK--- 579 VHRIGRTGR GN G+AT+F N+ + ++ DL LL+EAKQ+VP L+ + Sbjct: 517 VHRIGRTGRSGNTGIATTFINKACDESVLMDLKALLLEAKQKVPPVLQVLHCGDESMLDI 576 Query: 580 GGSRGRSKSNRFSGGFGAR 598 GG RG + F GG G R Sbjct: 577 GGERGCA----FCGGLGHR 591 >gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo sapiens] Length = 820 Score = 277 bits (708), Expect = 3e-74 Identities = 167/442 (37%), Positives = 238/442 (53%), Gaps = 33/442 (7%) Query: 162 DDIPVEATGSNCPPHIENFSDIDMGEIIMGNIELTRYTRPTPVQKHAIPIIKGKRDLMAC 221 +D + G P I ++ D + I+ I+ Y PTP+Q+ AIPI RD++ Sbjct: 375 EDYSITTKGGKIPNPIRSWKDSSLPPHILEVIDKCGYKEPTPIQRQAIPIGLQNRDIIGV 434 Query: 222 AQTGSGKTAAFLLPILSQIYTDGPGEALKAVKENGRYGRRKQYPISLVLAPTRELAVQIY 281 A+TGSGKTAAFL+P+L I T + + R Q P +++LAPTRELA QI Sbjct: 435 AETGSGKTAAFLIPLLVWITT---------LPKIDRIEESDQGPYAIILAPTRELAQQIE 485 Query: 282 EEARKFSYRSRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKY 341 EE KF +R V GG Q L GC +++ATPGRL+D++E + L C Y Sbjct: 486 EETIKFGKPLGIRTVAVIGGISREDQGFRLRMGCEIVIATPGRLIDVLENRYLVLSRCTY 545 Query: 342 LVLDEADRMLDMGFEPQIRRIVEQDTM------------PPKGV----------RHTMMF 379 +VLDEADRM+DMGFEP +++I+E + P K + R T+MF Sbjct: 546 VVLDEADRMIDMGFEPDVQKILEHMPVSNQKPDTDEAEDPEKMLANFESGKHKYRQTVMF 605 Query: 380 SATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVVWVEDLDKRSFLLDILGATGSD 439 +AT P ++ LAR +L + +G G E + QKV + + +KR LL IL G D Sbjct: 606 TATMPPAVERLARSYLRRPAVVYIGSAGKPHERVEQKVFLMSESEKRKKLLAIL-EQGFD 664 Query: 440 SLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAVA 499 ++FV KKG D L L GY ++HG + Q RE AL ++G ILVAT VA Sbjct: 665 PPIIIFVNQKKGCDVLAKSLEKMGYNACTLHGGKGQEQREFALSNLKAGAKDILVATDVA 724 Query: 500 ARGLDISNVRHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNEKNMNITKDLLDLLV 559 RG+DI +V V+N+D+ +IE+Y+HRIGRTGR G G+A +F +++ + +L ++ Sbjct: 725 GRGIDIQDVSMVVNYDMAKNIEDYIHRIGRTGRAGKSGVAITFLTKEDSAVFYELKQAIL 784 Query: 560 EAK-QEVPSWLENMAYEHHYKG 580 E+ P L N H G Sbjct: 785 ESPVSSCPPELANHPDAQHKPG 806 >gi|222352149 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 [Homo sapiens] Length = 648 Score = 272 bits (696), Expect = 6e-73 Identities = 157/386 (40%), Positives = 229/386 (59%), Gaps = 18/386 (4%) Query: 189 IMGNIELTRYTRPTPVQKHAIPIIKGKRDLMACAQTGSGKTAAFLLPILSQIYTDGPGEA 248 +M NI+ + +PTP+Q A PI+ DL+ AQTG+GKT +L+P + Sbjct: 253 VMENIKKAGFQKPTPIQSQAWPIVLQGIDLIGVAQTGTGKTLCYLMPGFIHL-------- 304 Query: 249 LKAVKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQI 308 V + G+R + P LVL PTRELA+Q+ E K+SY+ +R VYGG + +QI Sbjct: 305 ---VLQPSLKGQRNR-PGMLVLTPTRELALQVEGECCKYSYKG-LRSVCVYGGGNRDEQI 359 Query: 309 RDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTM 368 +L++G +++ATPGRL D+ + L YLVLDEAD+MLDMGFEPQI +I+ D Sbjct: 360 EELKKGVDIIIATPGRLNDLQMSNFVNLKNITYLVLDEADKMLDMGFEPQIMKIL-LDVR 418 Query: 369 PPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTS-ENITQKVVWVEDLDKRS 427 P R T+M SAT+P + LA+ +L E + + VG + + ++ Q ++ + +K S Sbjct: 419 PD---RQTVMTSATWPHSVHRLAQSYLKEPMIVYVGTLDLVAVSSVKQNIIVTTEEEKWS 475 Query: 428 FLLDILGATGSDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRS 487 + L + S +VFV K AD L L + S+HGDR QRDRE+AL F++ Sbjct: 476 HMQTFLQSMSSTDKVIVFVSRKAVADHLSSDLILGNISVESLHGDREQRDREKALENFKT 535 Query: 488 GKSPILVATAVAARGLDISNVRHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNEKN 547 GK IL+AT +A+RGLD+ +V HV NFD P +IEEYVHRIGRTGR G G++ + + Sbjct: 536 GKVRILIATDLASRGLDVHDVTHVYNFDFPRNIEEYVHRIGRTGRAGRTGVSITTLTRND 595 Query: 548 MNITKDLLDLLVEAKQEVPSWLENMA 573 + +L+++L A Q +P L +MA Sbjct: 596 WRVASELINILERANQSIPEELVSMA 621 >gi|45446747 DEAD box polypeptide 42 protein [Homo sapiens] Length = 938 Score = 268 bits (686), Expect = 9e-72 Identities = 165/459 (35%), Positives = 248/459 (54%), Gaps = 27/459 (5%) Query: 166 VEATGSNCPPHIENFSDIDMGEIIMGNIELTRYTRPTPVQKHAIPIIKGKRDLMACAQTG 225 + +G+ P +F+ E +M I + YT+PTP+Q +P+ RD++ A+TG Sbjct: 241 LRVSGAAPPRPGSSFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTG 300 Query: 226 SGKTAAFLLPILSQIYTDG---PGEALKAVKENGRYGRRKQYPISLVLAPTRELAVQIYE 282 SGKTAAF+ P+L I PG+ PI++++ PTREL QI+ Sbjct: 301 SGKTAAFIWPMLIHIMDQKELEPGDG----------------PIAVIVCPTRELCQQIHA 344 Query: 283 EARKFSYRSRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYL 342 E ++F +R VYGG + +Q + L+ G ++V TPGRL+D +++ L YL Sbjct: 345 ECKRFGKAYNLRSVAVYGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKKKATNLQRVSYL 404 Query: 343 VLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLA 402 V DEADRM DMGFE Q+R I + R T++FSATF K+I+ LARD L + I + Sbjct: 405 VFDEADRMFDMGFEYQVRSIASH----VRPDRQTLLFSATFRKKIEKLARDILIDPIRVV 460 Query: 403 VGRVGSTSENITQKV-VWVEDLDKRSFLLDILGATGSDSLTLVFVETKKGADSLEDFLYH 461 G +G +E++TQ V + K ++L L S L+FV K A+ L + L Sbjct: 461 QGDIGEANEDVTQIVEILHSGPSKWNWLTRRLVEFTSSGSVLLFVTKKANAEELANNLKQ 520 Query: 462 EGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVRHVINFDLPSDIE 521 EG+ +HGD Q +R + + F+ P+LVAT VAARGLDI +++ VIN+D+ DI+ Sbjct: 521 EGHNLGLLHGDMDQSERNKVISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDID 580 Query: 522 EYVHRIGRTGRVGNLGLATSFFNEKNMNITKDLLDLLVEAKQEVPSWLENMAYEHHYKGG 581 + HRIGRTGR G G+A + K+ N DL+ L A Q V L ++A ++ + Sbjct: 581 THTHRIGRTGRAGEKGVAYTLLTPKDSNFAGDLVRNLEGANQHVSKELLDLAMQNAWFRK 640 Query: 582 SRGR-SKSNRFSGGFGARDYRQSSGSSSSGFGASRGSSS 619 SR + K + + G G YR+ G S RG+++ Sbjct: 641 SRFKGGKGKKLNIGGGGLGYRERPGLGSENM--DRGNNN 677 >gi|45446743 DEAD box polypeptide 42 protein [Homo sapiens] Length = 938 Score = 268 bits (686), Expect = 9e-72 Identities = 165/459 (35%), Positives = 248/459 (54%), Gaps = 27/459 (5%) Query: 166 VEATGSNCPPHIENFSDIDMGEIIMGNIELTRYTRPTPVQKHAIPIIKGKRDLMACAQTG 225 + +G+ P +F+ E +M I + YT+PTP+Q +P+ RD++ A+TG Sbjct: 241 LRVSGAAPPRPGSSFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTG 300 Query: 226 SGKTAAFLLPILSQIYTDG---PGEALKAVKENGRYGRRKQYPISLVLAPTRELAVQIYE 282 SGKTAAF+ P+L I PG+ PI++++ PTREL QI+ Sbjct: 301 SGKTAAFIWPMLIHIMDQKELEPGDG----------------PIAVIVCPTRELCQQIHA 344 Query: 283 EARKFSYRSRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYL 342 E ++F +R VYGG + +Q + L+ G ++V TPGRL+D +++ L YL Sbjct: 345 ECKRFGKAYNLRSVAVYGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKKKATNLQRVSYL 404 Query: 343 VLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLA 402 V DEADRM DMGFE Q+R I + R T++FSATF K+I+ LARD L + I + Sbjct: 405 VFDEADRMFDMGFEYQVRSIASH----VRPDRQTLLFSATFRKKIEKLARDILIDPIRVV 460 Query: 403 VGRVGSTSENITQKV-VWVEDLDKRSFLLDILGATGSDSLTLVFVETKKGADSLEDFLYH 461 G +G +E++TQ V + K ++L L S L+FV K A+ L + L Sbjct: 461 QGDIGEANEDVTQIVEILHSGPSKWNWLTRRLVEFTSSGSVLLFVTKKANAEELANNLKQ 520 Query: 462 EGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVRHVINFDLPSDIE 521 EG+ +HGD Q +R + + F+ P+LVAT VAARGLDI +++ VIN+D+ DI+ Sbjct: 521 EGHNLGLLHGDMDQSERNKVISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDID 580 Query: 522 EYVHRIGRTGRVGNLGLATSFFNEKNMNITKDLLDLLVEAKQEVPSWLENMAYEHHYKGG 581 + HRIGRTGR G G+A + K+ N DL+ L A Q V L ++A ++ + Sbjct: 581 THTHRIGRTGRAGEKGVAYTLLTPKDSNFAGDLVRNLEGANQHVSKELLDLAMQNAWFRK 640 Query: 582 SRGR-SKSNRFSGGFGARDYRQSSGSSSSGFGASRGSSS 619 SR + K + + G G YR+ G S RG+++ Sbjct: 641 SRFKGGKGKKLNIGGGGLGYRERPGLGSENM--DRGNNN 677 >gi|55749865 DEAD (Asp-Glu-Ala-Asp) box polypeptide 53 [Homo sapiens] Length = 631 Score = 245 bits (625), Expect = 1e-64 Identities = 142/395 (35%), Positives = 220/395 (55%), Gaps = 18/395 (4%) Query: 200 RPTPVQKHAIPIIKGKRDLMACAQTGSGKTAAFLLPILSQIYTDGPGEALKAVKENGRYG 259 +PTP+Q A PII DL+ AQTG+GKT ++L+P I+ D + + + NG Sbjct: 244 KPTPIQSQAWPIILQGIDLIVVAQTGTGKTLSYLMP--GFIHLDS--QPISREQRNG--- 296 Query: 260 RRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQIRDLERGCHLLV 319 P LVL PTRELA+ + E K+SY+ C+ YGG + QI D+ +G +++ Sbjct: 297 -----PGMLVLTPTRELALHVEAECSKYSYKGLKSICI-YGGRNRNGQIEDISKGVDIII 350 Query: 320 ATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMF 379 ATPGRL D+ + L YLV+DEAD+MLDM FEPQIR+I+ D P R T+M Sbjct: 351 ATPGRLNDLQMNNSVNLRSITYLVIDEADKMLDMEFEPQIRKIL-LDVRPD---RQTVMT 406 Query: 380 SATFPKEIQMLARDFLDEYIFLAVGRVGSTSEN-ITQKVVWVEDLDKRSFLLDILGATGS 438 SAT+P ++ LA +L + + + VG + + N + Q ++ + +KR+ + + Sbjct: 407 SATWPDTVRQLALSYLKDPMIVYVGNLNLVAVNTVKQNIIVTTEKEKRALTQEFVENMSP 466 Query: 439 DSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAV 498 + ++FV K AD L +G + S+HG+ Q D+E A+ F+SG IL+ T + Sbjct: 467 NDKVIMFVSQKHIADDLSSDFNIQGISAESLHGNSEQSDQERAVEDFKSGNIKILITTDI 526 Query: 499 AARGLDISNVRHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNEKNMNITKDLLDLL 558 +RGLD+++V HV N+D P +I+ YVHR+G GR G G + + +++ + +L+ +L Sbjct: 527 VSRGLDLNDVTHVYNYDFPRNIDVYVHRVGYIGRTGKTGTSVTLITQRDSKMAGELIKIL 586 Query: 559 VEAKQEVPSWLENMAYEHHYKGGSRGRSKSNRFSG 593 A Q VP L MA ++ R R +R G Sbjct: 587 DRANQSVPEDLVVMAEQYKLNQQKRHRETRSRKPG 621 >gi|188035877 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 [Homo sapiens] Length = 619 Score = 230 bits (587), Expect = 3e-60 Identities = 145/417 (34%), Positives = 229/417 (54%), Gaps = 25/417 (5%) Query: 177 IENFSDIDMGEIIMGNIELTRYTRPTPVQKHAIPIIKGKRDLMACAQTGSGKTAAFLLPI 236 I +F + E++ N++ + Y PTP+Q IP+ RD++A A TGSGKTAAFLLP+ Sbjct: 202 IIDFEHCSLPEVLNHNLKKSGYEVPTPIQMQMIPVGLLGRDILASADTGSGKTAAFLLPV 261 Query: 237 LSQIYTDGPGEALKAVKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKF-SYRSRVRP 295 + ++A+ E+ + P +L+L PTRELA+QI +A++ S R++ Sbjct: 262 I-----------MRALFES-------KTPSALILTPTRELAIQIERQAKELMSGLPRMKT 303 Query: 296 CVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGF 355 ++ GG + Q+ L++ +++ATPGRL+D++++ + L K +V+DEAD ML MGF Sbjct: 304 VLLVGGLPLPPQLYRLQQHVKVIIATPGRLLDIIKQSSVELCGVKIVVVDEADTMLKMGF 363 Query: 356 EPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQ 415 + Q+ I+E P + T++ SAT P I+ LA L + + G N+ Q Sbjct: 364 QQQVLDILENI---PNDCQ-TILVSATIPTSIEQLASQLLHNPVRIITGEKNLPCANVRQ 419 Query: 416 KVVWVEDLDKRSFLLDILGATGS-DSLTLVFVETKKGADSLEDFLYH-EGYACTSIHGDR 473 ++WVED K+ L +IL LVFV+ K GAD L + + G SIH ++ Sbjct: 420 IILWVEDPAKKKKLFEILNDKKLFKPPVLVFVDCKLGADLLSEAVQKITGLKSISIHSEK 479 Query: 474 SQRDREEALHQFRSGKSPILVATAVAARGLDISNVRHVINFDLPSDIEEYVHRIGRTGRV 533 SQ +R+ L G ++V+T V RGLD+ +VR V+NFD+PS ++EYVH+IGR GR+ Sbjct: 480 SQIERKNILKGLLEGDYEVVVSTGVLGRGLDLISVRLVVNFDMPSSMDEYVHQIGRVGRL 539 Query: 534 GNLGLATSFFNEKNMNITKDLLDLLVEAKQEVPSWLENMAYEHHYKGGSRGRSKSNR 590 G G A +F N + + D+ + +P L N Y H K + + K + Sbjct: 540 GQNGTAITFINNNSKRLFWDIAKRVKPTGSILPPQLLNSPYLHDQKRKEQQKDKQTQ 596 >gi|224593278 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 [Homo sapiens] Length = 796 Score = 211 bits (538), Expect = 1e-54 Identities = 133/383 (34%), Positives = 205/383 (53%), Gaps = 28/383 (7%) Query: 179 NFSDIDMGEIIMGNIELTRYTRPTPVQKHAIPIIKGKRDLMACAQTGSGKTAAFLLPILS 238 +F D+++ ++ I + +PTP+QK IP+ +D+ ACA TG+GKTAAF LP+L Sbjct: 219 SFQDMNLSRPLLKAITAMGFKQPTPIQKACIPVGLLGKDICACAATGTGKTAAFALPVLE 278 Query: 239 QIYTDGPGEALKAVKENGRYGRRKQYPIS--LVLAPTRELAVQIYEEARKFSYRSRVRPC 296 ++ + +Q P++ LVL PTREL +Q++ R+ + + C Sbjct: 279 RLIY-----------------KPRQAPVTRVLVLVPTRELGIQVHSVTRQLAQFCNITTC 321 Query: 297 VVYGGADIGQQIRDLERGCHLLVATPGRLVDMMER-GKIGLDFCKYLVLDEADRMLDMGF 355 + GG D+ Q L +L+ATPGRL+D + L + L+LDEADRMLD F Sbjct: 322 LAVGGLDVKSQEAALRAAPDILIATPGRLIDHLHNCPSFHLSSIEVLILDEADRMLDEYF 381 Query: 356 EPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQ 415 E Q++ I+ + R TM+FSAT E++ LA L + + V + + Q Sbjct: 382 EEQMKEIIRMCSHH----RQTMLFSATMTDEVKDLASVSLKNPVRIFVNSNTDVAPFLRQ 437 Query: 416 KVVWVE---DLDKRSFLLDILGATGSDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGD 472 + + + + D+ + + +L T +D + L F +TKK A + L G +HG+ Sbjct: 438 EFIRIRPNREGDREAIVAALLTRTFTDHVML-FTQTKKQAHRMHILLGLMGLQVGELHGN 496 Query: 473 RSQRDREEALHQFRSGKSPILVATAVAARGLDISNVRHVINFDLPSDIEEYVHRIGRTGR 532 SQ R EAL +F+ + ILVAT VAARGLDI V+ VINF +P+ I+ YVHR+GRT R Sbjct: 497 LSQTQRLEALRRFKDEQIDILVATDVAARGLDIEGVKTVINFTMPNTIKHYVHRVGRTAR 556 Query: 533 VGNLGLATSFFNEKNMNITKDLL 555 G G + S E + K+++ Sbjct: 557 AGRAGRSVSLVGEDERKMLKEIV 579 >gi|20149629 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 1 [Homo sapiens] Length = 455 Score = 210 bits (535), Expect = 3e-54 Identities = 131/382 (34%), Positives = 207/382 (54%), Gaps = 24/382 (6%) Query: 178 ENFSDIDMGEIIMGNIELTRYTRPTPVQKHAIPIIKGKRDLMACAQTGSGKTAAFLLPIL 237 + F D+ + +++ + +T+PT +Q AIP+ RD++ A+TGSGKT AF LPIL Sbjct: 24 KTFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAFALPIL 83 Query: 238 SQIYTDGPGEALKAVKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCV 297 + + Q +LVL PTRELA QI E+ V+ V Sbjct: 84 NALL------------------ETPQRLFALVLTPTRELAFQISEQFEALGSSIGVQSAV 125 Query: 298 VYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGK-IGLDFCKYLVLDEADRMLDMGFE 356 + GG D Q L + H+++ATPGRL+D +E K L KYLV+DEADR+L+M FE Sbjct: 126 IVGGIDSMSQSLALAKKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRILNMDFE 185 Query: 357 PQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQK 416 ++ +I++ + P+ R T +FSAT K++Q L R L + AV T E + Q Sbjct: 186 TEVDKILK---VIPRD-RKTFLFSATMTKKVQKLQRAALKNPVKCAVSSKYQTVEKLQQY 241 Query: 417 VVWVEDLDKRSFLLDILGATGSDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQR 476 +++ K ++L+ IL +S ++F T L + G+ +HG SQ Sbjct: 242 YIFIPSKFKDTYLVYILNELAGNSF-MIFCSTCNNTQRTALLLRNLGFTAIPLHGQMSQS 300 Query: 477 DREEALHQFRSGKSPILVATAVAARGLDISNVRHVINFDLPSDIEEYVHRIGRTGRVGNL 536 R +L++F++ IL+AT VA+RGLDI +V V+NFD+P+ ++Y+HR+GRT R G Sbjct: 301 KRLGSLNKFKAKARSILLATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRS 360 Query: 537 GLATSFFNEKNMNITKDLLDLL 558 G A +F + ++ + + + L+ Sbjct: 361 GKAITFVTQYDVELFQRIEHLI 382 >gi|7661920 eukaryotic translation initiation factor 4A, isoform 3 [Homo sapiens] Length = 411 Score = 209 bits (531), Expect = 9e-54 Identities = 141/414 (34%), Positives = 219/414 (52%), Gaps = 34/414 (8%) Query: 154 TGINFEKYDDIPVEATGSNCPPHIENFSDIDMGEIIMGNIELTRYTRPTPVQKHAIP-II 212 T + FE +++ V T F + + E ++ I + +P+ +Q+ AI II Sbjct: 24 TKVEFETSEEVDVTPT----------FDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQII 73 Query: 213 KGKRDLMACAQTGSGKTAAFLLPILSQIYTDGPGEALKAVKENGRYGRRKQYPISLVLAP 272 KG RD++A +Q+G+GKTA F + +L + V+E +L+LAP Sbjct: 74 KG-RDVIAQSQSGTGKTATFSISVLQCLDIQ--------VRETQ----------ALILAP 114 Query: 273 TRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERG 332 TRELAVQI + V+ GG ++G+ IR L+ G H++ TPGR+ DM+ R Sbjct: 115 TRELAVQIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRRR 174 Query: 333 KIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLAR 392 + K LVLDEAD ML+ GF+ QI + +PP ++ SAT P EI + Sbjct: 175 SLRTRAIKMLVLDEADEMLNKGFKEQIYDVYRY--LPP--ATQVVLISATLPHEILEMTN 230 Query: 393 DFLDEYIFLAVGRVGSTSENITQKVVWVEDLDKRSFLLDILGATGSDSLTLVFVETKKGA 452 F+ + I + V R T E I Q V VE + + L L T + + ++F TK+ Sbjct: 231 KFMTDPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCNTKRKV 290 Query: 453 DSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVRHVI 512 D L + + + +S+HGD Q++RE + +FRSG S +L++T V ARGLD+ V +I Sbjct: 291 DWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLII 350 Query: 513 NFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNEKNMNITKDLLDLLVEAKQEVP 566 N+DLP++ E Y+HRIGR+GR G G+A +F ++ I +D+ E+P Sbjct: 351 NYDLPNNRELYIHRIGRSGRYGRKGVAINFVKNDDIRILRDIEQYYSTQIDEMP 404 >gi|38569503 ATP-dependent RNA helicase ROK1 isoform b [Homo sapiens] Length = 491 Score = 206 bits (524), Expect = 6e-53 Identities = 141/440 (32%), Positives = 232/440 (52%), Gaps = 34/440 (7%) Query: 145 EQELFSGGNTGINFEKYDDI----PVEATGSNCPPHIENFSDID----MGEIIMGNIELT 196 E +L SG + EK + + + G++ P I F +D + ++ NI Sbjct: 16 ESKLTSGKLENLRKEKINFLRNKHKIHVQGTDLPDPIATFQQLDQEYKINSRLLQNILDA 75 Query: 197 RYTRPTPVQKHAIPIIKGKRDLMACAQTGSGKTAAFLLPILSQIYTDGPGEALKAVKENG 256 + PTP+Q AIP++ R+L+A A TGSGKT AF +PIL Q+ K+ Sbjct: 76 GFQMPTPIQMQAIPVMLHGRELLASAPTGSGKTLAFSIPILMQL------------KQPA 123 Query: 257 RYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQIRDLE-RGC 315 G R +L+++PTRELA QI+ E K S + R +++ A ++ + Sbjct: 124 NKGFR-----ALIISPTRELASQIHRELIKISEGTGFRIHMIHKAAVAAKKFGPKSSKKF 178 Query: 316 HLLVATPGRLVDMMERGKIGLDFC--KYLVLDEADRMLD---MGFEPQIRRIVEQDTMPP 370 +LV TP RL+ ++++ G+D ++LV+DE+D++ + GF Q+ I T Sbjct: 179 DILVTTPNRLIYLLKQDPPGIDLASVEWLVVDESDKLFEDGKTGFRDQLASIFLACTSHK 238 Query: 371 KGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVVWVEDLDKRSFLL 430 VR M FSATF +++ + LD I +++G S E + Q++++V + + Sbjct: 239 --VRRAM-FSATFAYDVEQWCKLNLDNVISVSIGARNSAVETVEQELLFVGSETGKLLAM 295 Query: 431 DILGATGSDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKS 490 L G + LVFV++ + A L L +EG IH +R+Q+ R+ +H FR+GK Sbjct: 296 RELVKKGFNPPVLVFVQSIERAKELFHELIYEGINVDVIHAERTQQQRDNTVHSFRAGKI 355 Query: 491 PILVATAVAARGLDISNVRHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNEKNMNI 550 +L+ TA+ ARG+D V VIN+D P+ EY+HRIGRTGR GN G A +FF E + + Sbjct: 356 WVLICTALLARGIDFKGVNLVINYDFPTSSVEYIHRIGRTGRAGNKGKAITFFTEDDKPL 415 Query: 551 TKDLLDLLVEAKQEVPSWLE 570 + + +++ +A VP +++ Sbjct: 416 LRSVANVIQQAGCPVPEYIK 435 >gi|38569505 ATP-dependent RNA helicase ROK1 isoform a [Homo sapiens] Length = 599 Score = 206 bits (524), Expect = 6e-53 Identities = 141/440 (32%), Positives = 232/440 (52%), Gaps = 34/440 (7%) Query: 145 EQELFSGGNTGINFEKYDDI----PVEATGSNCPPHIENFSDID----MGEIIMGNIELT 196 E +L SG + EK + + + G++ P I F +D + ++ NI Sbjct: 124 ESKLTSGKLENLRKEKINFLRNKHKIHVQGTDLPDPIATFQQLDQEYKINSRLLQNILDA 183 Query: 197 RYTRPTPVQKHAIPIIKGKRDLMACAQTGSGKTAAFLLPILSQIYTDGPGEALKAVKENG 256 + PTP+Q AIP++ R+L+A A TGSGKT AF +PIL Q+ K+ Sbjct: 184 GFQMPTPIQMQAIPVMLHGRELLASAPTGSGKTLAFSIPILMQL------------KQPA 231 Query: 257 RYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQIRDLE-RGC 315 G R +L+++PTRELA QI+ E K S + R +++ A ++ + Sbjct: 232 NKGFR-----ALIISPTRELASQIHRELIKISEGTGFRIHMIHKAAVAAKKFGPKSSKKF 286 Query: 316 HLLVATPGRLVDMMERGKIGLDFC--KYLVLDEADRMLD---MGFEPQIRRIVEQDTMPP 370 +LV TP RL+ ++++ G+D ++LV+DE+D++ + GF Q+ I T Sbjct: 287 DILVTTPNRLIYLLKQDPPGIDLASVEWLVVDESDKLFEDGKTGFRDQLASIFLACTSHK 346 Query: 371 KGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVVWVEDLDKRSFLL 430 VR M FSATF +++ + LD I +++G S E + Q++++V + + Sbjct: 347 --VRRAM-FSATFAYDVEQWCKLNLDNVISVSIGARNSAVETVEQELLFVGSETGKLLAM 403 Query: 431 DILGATGSDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKS 490 L G + LVFV++ + A L L +EG IH +R+Q+ R+ +H FR+GK Sbjct: 404 RELVKKGFNPPVLVFVQSIERAKELFHELIYEGINVDVIHAERTQQQRDNTVHSFRAGKI 463 Query: 491 PILVATAVAARGLDISNVRHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNEKNMNI 550 +L+ TA+ ARG+D V VIN+D P+ EY+HRIGRTGR GN G A +FF E + + Sbjct: 464 WVLICTALLARGIDFKGVNLVINYDFPTSSVEYIHRIGRTGRAGNKGKAITFFTEDDKPL 523 Query: 551 TKDLLDLLVEAKQEVPSWLE 570 + + +++ +A VP +++ Sbjct: 524 LRSVANVIQQAGCPVPEYIK 543 >gi|4503529 eukaryotic translation initiation factor 4A isoform 1 [Homo sapiens] Length = 406 Score = 202 bits (514), Expect = 8e-52 Identities = 130/398 (32%), Positives = 216/398 (54%), Gaps = 25/398 (6%) Query: 171 SNCPPHIENFSDIDMGEIIMGNIELTRYTRPTPVQKHAI-PIIKGKRDLMACAQTGSGKT 229 SN +++F D+++ E ++ I + +P+ +Q+ AI P IKG D++A AQ+G+GKT Sbjct: 25 SNWNEIVDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGY-DVIAQAQSGTGKT 83 Query: 230 AAFLLPILSQIYTDGPGEALKAVKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSY 289 A F + IL QI D LKA + +LVLAPTRELA QI + Sbjct: 84 ATFAISILQQIELD-----LKATQ-------------ALVLAPTRELAQQIQKVVMALGD 125 Query: 290 RSRVRPCVVYGGADIGQQIRDLERGC-HLLVATPGRLVDMMERGKIGLDFCKYLVLDEAD 348 GG ++ +++ L+ H++V TPGR+ DM+ R + + K VLDEAD Sbjct: 126 YMGASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEAD 185 Query: 349 RMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGS 408 ML GF+ QI I ++ + V + SAT P ++ + + F+ + I + V + Sbjct: 186 EMLSRGFKDQIYDIFQKLNSNTQVV----LLSATMPSDVLEVTKKFMRDPIRILVKKEEL 241 Query: 409 TSENITQKVVWVEDLDKRSFLLDILGATGSDSLTLVFVETKKGADSLEDFLYHEGYACTS 468 T E I Q + VE + + L L T + + ++F+ T++ D L + ++ + ++ Sbjct: 242 TLEGIRQFYINVEREEWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVSA 301 Query: 469 IHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVRHVINFDLPSDIEEYVHRIG 528 +HGD Q++R+ + +FRSG S +L+ T + ARG+D+ V VIN+DLP++ E Y+HRIG Sbjct: 302 MHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIG 361 Query: 529 RTGRVGNLGLATSFFNEKNMNITKDLLDLLVEAKQEVP 566 R GR G G+A + E++ +D+ + +E+P Sbjct: 362 RGGRFGRKGVAINMVTEEDKRTLRDIETFYNTSIEEMP 399 >gi|83700235 eukaryotic translation initiation factor 4A2 [Homo sapiens] Length = 407 Score = 202 bits (513), Expect = 1e-51 Identities = 136/422 (32%), Positives = 224/422 (53%), Gaps = 28/422 (6%) Query: 150 SGGNTGINFEKYDDIPVEATG---SNCPPHIENFSDIDMGEIIMGNIELTRYTRPTPVQK 206 SGG+ N E ++ G SN ++NF D+++ E ++ I + +P+ +Q+ Sbjct: 2 SGGSADYNREHGGPEGMDPDGVIESNWNEIVDNFDDMNLKESLLRGIYAYGFEKPSAIQQ 61 Query: 207 HAI-PIIKGKRDLMACAQTGSGKTAAFLLPILSQIYTDGPGEALKAVKENGRYGRRKQYP 265 AI P IKG D++A AQ+G+GKTA F + IL Q+ + KE Sbjct: 62 RAIIPCIKGY-DVIAQAQSGTGKTATFAISILQQLEIE--------FKETQ--------- 103 Query: 266 ISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQIRDLERGC-HLLVATPGR 324 +LVLAPTRELA QI + GG ++ +++ L+ H++V TPGR Sbjct: 104 -ALVLAPTRELAQQIQKVILALGDYMGATCHACIGGTNVRNEMQKLQAEAPHIVVGTPGR 162 Query: 325 LVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFP 384 + DM+ R + + K VLDEAD ML GF+ QI I ++ + V + SAT P Sbjct: 163 VFDMLNRRYLSPKWIKMFVLDEADEMLSRGFKDQIYEIFQKLNTSIQVV----LLSATMP 218 Query: 385 KEIQMLARDFLDEYIFLAVGRVGSTSENITQKVVWVEDLDKRSFLLDILGATGSDSLTLV 444 ++ + + F+ + I + V + T E I Q + VE + + L L T + + ++ Sbjct: 219 TDVLEVTKKFMRDPIRILVKKEELTLEGIKQFYINVEREEWKLDTLCDLYETLTITQAVI 278 Query: 445 FVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLD 504 F+ T++ D L + ++ + +++HGD Q++R+ + +FRSG S +L+ T + ARG+D Sbjct: 279 FLNTRRKVDWLTEKMHARDFTVSALHGDMDQKERDVIMREFRSGSSRVLITTDLLARGID 338 Query: 505 ISNVRHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNEKNMNITKDLLDLLVEAKQE 564 + V VIN+DLP++ E Y+HRIGR GR G G+A +F E++ I +D+ +E Sbjct: 339 VQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINFVTEEDKRILRDIETFYNTTVEE 398 Query: 565 VP 566 +P Sbjct: 399 MP 400 >gi|50659095 DEAD (Asp-Glu-Ala-Asp) box polypeptide 21 [Homo sapiens] Length = 783 Score = 187 bits (476), Expect = 2e-47 Identities = 143/440 (32%), Positives = 218/440 (49%), Gaps = 44/440 (10%) Query: 118 ERSGHSRWCDKSVEDDWSKPLP---PSERLEQELFSGGNTGINFEKYDDIPVEATGSNCP 174 E +G +R +++ + P P PSE +E N E +IPVE Sbjct: 138 EMNGETREKSPKLKNGFPHPEPDCNPSEAASEES--------NSEIEQEIPVEQKEGA-- 187 Query: 175 PHIENFSDIDMGEIIMGNIELTRYTRPTPVQKHAIPIIKGKRDLMACAQTGSGKTAAFLL 234 FS+ + E + ++ T P+Q + +DL+A A+TG+GKT +F + Sbjct: 188 -----FSNFPISEETIKLLKGRGVTFLFPIQAKTFHHVYSGKDLIAQARTGTGKTFSFAI 242 Query: 235 PILSQIYTDGPGEALKAVKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVR 294 P++ +++ GE ++ + GR Q LVLAPTRELA Q+ ++ + + V Sbjct: 243 PLIEKLH----GEL-----QDRKRGRAPQV---LVLAPTRELANQVSKDFSDITKKLSV- 289 Query: 295 PCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMG 354 YGG G Q + G +LV TPGR+ D ++ GK+ L K++VLDE D+MLDMG Sbjct: 290 -ACFYGGTPYGGQFERMRNGIDILVGTPGRIKDHIQNGKLDLTKLKHVVLDEVDQMLDMG 348 Query: 355 FEPQIRRIVEQD-TMPPKGVRHTMMFSATFPKEIQMLARDFLD------EYIFLAVGRVG 407 F Q+ I+ + T++FSAT P + +A+ ++ + I + Sbjct: 349 FADQVEEILSVAYKKDSEDNPQTLLFSATCPHWVFNVAKKYMKSTYEQVDLIGKKTQKTA 408 Query: 408 STSENITQKVVWVEDLDKRSFLLDILGA-TGSDSLTLVFVETKKGADSLEDFLYHEGYAC 466 T E++ K W + + + + D++ +G T++F ETKK A L + A Sbjct: 409 ITVEHLAIKCHWTQ---RAAVIGDVIRVYSGHQGRTIIFCETKKEAQELSQNSAIKQDA- 464 Query: 467 TSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVRHVINFDLPSDIEEYVHR 526 S+HGD Q+ RE L FR+G +LVAT VAARGLDI V VI P D+E Y+HR Sbjct: 465 QSLHGDIPQKQREITLKGFRNGSFGVLVATNVAARGLDIPEVDLVIQSSPPKDVESYIHR 524 Query: 527 IGRTGRVGNLGLATSFFNEK 546 GRTGR G G+ F+ K Sbjct: 525 SGRTGRAGRTGVCICFYQHK 544 >gi|13129006 nucleolar protein GU2 [Homo sapiens] Length = 737 Score = 182 bits (461), Expect = 1e-45 Identities = 120/376 (31%), Positives = 196/376 (52%), Gaps = 28/376 (7%) Query: 180 FSDIDMGEIIMGNIELTRYTRPTPVQKHAI-PIIKGKRDLMACAQTGSGKTAAFLLPILS 238 FS+ + E + ++ T P+Q P+ +GK DL+A A+TG+GKT +F +P++ Sbjct: 139 FSNFPISEETIKLLKGRGVTYLFPIQVKTFGPVYEGK-DLIAQARTGTGKTFSFAIPLIE 197 Query: 239 QIYTDGPGEALKAVKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVV 298 ++ + N ++ + P LVLAPTRELA Q+ ++ + + + V Sbjct: 198 RL------------QRNQETIKKSRSPKVLVLAPTRELANQVAKDFKDITRKLSV--ACF 243 Query: 299 YGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQ 358 YGG QI + G +LV TPGR+ D ++ G++ L +++VLDE D+MLD+GF Q Sbjct: 244 YGGTSYQSQINHIRNGIDILVGTPGRIKDHLQSGRLDLSKLRHVVLDEVDQMLDLGFAEQ 303 Query: 359 IRRIVEQD-TMPPKGVRHTMMFSATFPKEIQMLARDFLD------EYIFLAVGRVGSTSE 411 + I+ + + T++FSAT P+ + +A+ ++ + + + +T E Sbjct: 304 VEDIIHESYKTDSEDNPQTLLFSATCPQWVYKVAKKYMKSRYEQVDLVGKMTQKAATTVE 363 Query: 412 NITQKVVWVEDLDKRSFLLDILGA-TGSDSLTLVFVETKKGADSLEDFLYHEGYACTSIH 470 ++ + W + + + + D+L +GS+ ++F ETKK + H +H Sbjct: 364 HLAIQCHWSQ---RPAVIGDVLQVYSGSEGRAIIFCETKKNVTEMA-MNPHIKQNAQCLH 419 Query: 471 GDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVRHVINFDLPSDIEEYVHRIGRT 530 GD +Q RE L FR G +LVAT VAARGLDI V VI P D+E Y+HR GRT Sbjct: 420 GDIAQSQREITLKGFREGSFKVLVATNVAARGLDIPEVDLVIQSSPPQDVESYIHRSGRT 479 Query: 531 GRVGNLGLATSFFNEK 546 GR G G+ F+ + Sbjct: 480 GRAGRTGICICFYQPR 495 >gi|164664518 DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 [Homo sapiens] Length = 483 Score = 180 bits (457), Expect = 3e-45 Identities = 120/393 (30%), Positives = 204/393 (51%), Gaps = 26/393 (6%) Query: 187 EIIMGNIELTRYTRPTPVQKHAIPIIKGKRDLMACAQTGSGKTAAFLLPILSQIYTDGPG 246 E++MG E+ + +P+P+Q+ +IPI RD++A A+ G+GK+ A+L+P+L Sbjct: 106 ELLMGIFEMG-WEKPSPIQEESIPIALSGRDILARAKNGTGKSGAYLIPLL--------- 155 Query: 247 EALKAVKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFS-YRSRVRPCVVYGGADIG 305 E L K+N + ++V+ PTRELA+Q+ + + S + + GG ++ Sbjct: 156 ERLDLKKDNIQ---------AMVIVPTRELALQVSQICIQVSKHMGGAKVMATTGGTNLR 206 Query: 306 QQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQ 365 I L+ H+++ATPGR++D++++G +D + +VLDEAD++L F + I+ Sbjct: 207 DDIMRLDDTVHVVIATPGRILDLIKKGVAKVDHVQMIVLDEADKLLSQDFVQIMEDIIL- 265 Query: 366 DTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVVWVEDLDK 425 T+P R +++SATFP +Q L + + + T + +TQ +V + K Sbjct: 266 -TLPKN--RQILLYSATFPLSVQKFMNSHLQKPYEINL-MEELTLKGVTQYYAYVTERQK 321 Query: 426 RSFLLDILGATGSDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQF 485 L+ L + + +++F + + + L + GY+C IH Q R H F Sbjct: 322 -VHCLNTLFSRLQINQSIIFCNSSQRVELLAKKISQLGYSCFYIHAKMRQEHRNRVFHDF 380 Query: 486 RSGKSPILVATAVAARGLDISNVRHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNE 545 R+G LV T + RG+DI V VINFD P E Y+HRIGR+GR G+LGLA + Sbjct: 381 RNGLCRNLVCTDLFTRGIDIQAVNVVINFDFPKLAETYLHRIGRSGRFGHLGLAINLITY 440 Query: 546 KNMNITKDLLDLLVEAKQEVPSWLENMAYEHHY 578 + K + + L + +PS ++ Y Y Sbjct: 441 DDRFNLKSIEEQLGTEIKPIPSNIDKSLYVAEY 473 >gi|51094101 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 2 [Homo sapiens] Length = 881 Score = 180 bits (456), Expect = 4e-45 Identities = 116/363 (31%), Positives = 185/363 (50%), Gaps = 21/363 (5%) Query: 180 FSDIDMGEIIMGNIELTRYTRPTPVQKHAIPIIKGKRDLMACAQTGSGKTAAFLLPILSQ 239 F + + + I Y PTP+Q+ IP+I +D++A A+TGSGKTA FLLP+ + Sbjct: 98 FQSMGLSYPVFKGIMKKGYKVPTPIQRKTIPVILDGKDVVAMARTGSGKTACFLLPMFER 157 Query: 240 IYTDGPGEALKAVKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVY 299 + T +A L+L+PTRELA+Q + ++ + ++ ++ Sbjct: 158 LKTHSAQTGARA----------------LILSPTRELALQTLKFTKELGKFTGLKTALIL 201 Query: 300 GGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQI 359 GG + Q L +++ATPGRLV + + L +Y+V DEADR+ +MGF Q+ Sbjct: 202 GGDRMEDQFAALHENPDIIIATPGRLVHVAVEMSLKLQSVEYVVFDEADRLFEMGFAEQL 261 Query: 360 RRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVVW 419 + I+ + +P G T++FSAT PK + AR L E + + + +E + Sbjct: 262 QEIIAR--LP--GGHQTVLFSATLPKLLVEFARAGLTEPVLIRLDVDTKLNEQLKTSFFL 317 Query: 420 VEDLDKRSFLLDIL-GATGSDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDR 478 V + K + LL +L T+VFV TK A+ L + L + +C I+ R Sbjct: 318 VREDTKAAVLLHLLHNVVRPQDQTVVFVATKHHAEYLTELLTTQRVSCAHIYSALDPTAR 377 Query: 479 EEALHQFRSGKSPILVATAVAARGLDISNVRHVINFDLPSDIEEYVHRIGRTGRVGNLGL 538 + L +F GK L+ T +AARGLDI + +VIN+ P+ + ++HR+GR R G G Sbjct: 378 KINLAKFTLGKCSTLIVTDLAARGLDIPLLDNVINYSFPAKGKLFLHRVGRVARAGRSGT 437 Query: 539 ATS 541 A S Sbjct: 438 AYS 440 >gi|164419743 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 1 [Homo sapiens] Length = 882 Score = 180 bits (456), Expect = 4e-45 Identities = 116/363 (31%), Positives = 185/363 (50%), Gaps = 21/363 (5%) Query: 180 FSDIDMGEIIMGNIELTRYTRPTPVQKHAIPIIKGKRDLMACAQTGSGKTAAFLLPILSQ 239 F + + + I Y PTP+Q+ IP+I +D++A A+TGSGKTA FLLP+ + Sbjct: 98 FQSMGLSYPVFKGIMKKGYKVPTPIQRKTIPVILDGKDVVAMARTGSGKTACFLLPMFER 157 Query: 240 IYTDGPGEALKAVKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVY 299 + T +A L+L+PTRELA+Q + ++ + ++ ++ Sbjct: 158 LKTHSAQTGARA----------------LILSPTRELALQTLKFTKELGKFTGLKTALIL 201 Query: 300 GGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQI 359 GG + Q L +++ATPGRLV + + L +Y+V DEADR+ +MGF Q+ Sbjct: 202 GGDRMEDQFAALHENPDIIIATPGRLVHVAVEMSLKLQSVEYVVFDEADRLFEMGFAEQL 261 Query: 360 RRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVVW 419 + I+ + +P G T++FSAT PK + AR L E + + + +E + Sbjct: 262 QEIIAR--LP--GGHQTVLFSATLPKLLVEFARAGLTEPVLIRLDVDTKLNEQLKTSFFL 317 Query: 420 VEDLDKRSFLLDIL-GATGSDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDR 478 V + K + LL +L T+VFV TK A+ L + L + +C I+ R Sbjct: 318 VREDTKAAVLLHLLHNVVRPQDQTVVFVATKHHAEYLTELLTTQRVSCAHIYSALDPTAR 377 Query: 479 EEALHQFRSGKSPILVATAVAARGLDISNVRHVINFDLPSDIEEYVHRIGRTGRVGNLGL 538 + L +F GK L+ T +AARGLDI + +VIN+ P+ + ++HR+GR R G G Sbjct: 378 KINLAKFTLGKCSTLIVTDLAARGLDIPLLDNVINYSFPAKGKLFLHRVGRVARAGRSGT 437 Query: 539 ATS 541 A S Sbjct: 438 AYS 440 >gi|31542656 DEAD (Asp-Glu-Ala-Asp) box polypeptide 49 [Homo sapiens] Length = 483 Score = 178 bits (452), Expect = 1e-44 Identities = 123/392 (31%), Positives = 198/392 (50%), Gaps = 29/392 (7%) Query: 180 FSDIDMGEIIMGNIELTRYTRPTPVQKHAIPIIKGKRDLMACAQTGSGKTAAFLLPILSQ 239 F+++ + ++ +PTPVQ IP I RD + CA+TGSGKTAAF+LPIL + Sbjct: 4 FAELGLSSWLVEQCRQLGLKQPTPVQLGCIPAILEGRDCLGCAKTGSGKTAAFVLPILQK 63 Query: 240 IYTDGPGEALKAVKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVY 299 + D G LVL PTRELA QI E+ R ++ C++ Sbjct: 64 LSEDPYGI------------------FCLVLTPTRELAYQIAEQFRVLGKPLGLKDCIIV 105 Query: 300 GGADIGQQIRDLERGCHLLVATPGRLVDMMERGK-IGLDFCKYLVLDEADRMLDMG---F 355 GG D+ Q +L R H+++ATPGRL D + + ++LV+DEADR+L+ G F Sbjct: 106 GGMDMVAQALELSRKPHVVIATPGRLADHLRSSNTFSIKKIRFLVMDEADRLLEQGCTDF 165 Query: 356 EPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQ 415 + I+ +P + R T++FSAT ++ L ++ F ST E + Q Sbjct: 166 TVDLEAILA--AVPAR--RQTLLFSATLTDTLRELQGLATNQPFFWEAQAPVSTVEQLDQ 221 Query: 416 KVVWVEDLDKRSFLLDILGA---TGSDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGD 472 + + V + K ++L+ ++ D ++F T K L L + ++H Sbjct: 222 RYLLVPEKVKDAYLVHLIQRFQDEHEDWSIIIFTNTCKTCQILCMMLRKFSFPTVALHSM 281 Query: 473 RSQRDREEALHQFRSGKSPILVATAVAARGLDISNVRHVINFDLPSDIEEYVHRIGRTGR 532 Q++R AL +F+S IL+AT VA+RGLDI V+ VIN + P + Y+HR+GRT R Sbjct: 282 MKQKERFAALAKFKSSIYRILIATDVASRGLDIPTVQVVINHNTPGLPKIYIHRVGRTAR 341 Query: 533 VGNLGLATSFFNEKNMNITKDLLDLLVEAKQE 564 G G A + + ++++ + + + + +E Sbjct: 342 AGRQGQAITLVTQYDIHLVHAIEEQIKKKLEE 373 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.317 0.137 0.410 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 26,856,949 Number of Sequences: 37866 Number of extensions: 1318511 Number of successful extensions: 11529 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 237 Number of HSP's successfully gapped in prelim test: 166 Number of HSP's that attempted gapping in prelim test: 5573 Number of HSP's gapped (non-prelim): 2941 length of query: 660 length of database: 18,247,518 effective HSP length: 109 effective length of query: 551 effective length of database: 14,120,124 effective search space: 7780188324 effective search space used: 7780188324 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.