Guide to the Human Genome
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Search of human proteins with 169218113

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|169218113 PREDICTED: similar to plakophilin 1, partial [Homo
sapiens]
         (625 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|53729344 plakophilin 1 isoform 1a [Homo sapiens]                  1259   0.0  
gi|169218113 PREDICTED: similar to plakophilin 1, partial [Homo ...  1259   0.0  
gi|53729346 plakophilin 1 isoform 1b [Homo sapiens]                  1246   0.0  
gi|148664186 plakophilin 2 isoform 2a [Homo sapiens]                  362   e-100
gi|148664226 plakophilin 2 isoform 2b [Homo sapiens]                  341   1e-93
gi|53829376 plakophilin 4 isoform b [Homo sapiens]                    273   5e-73
gi|53829374 plakophilin 4 isoform a [Homo sapiens]                    273   5e-73
gi|11034811 catenin (cadherin-associated protein), delta 2 (neur...   263   3e-70
gi|6005830 plakophilin 3 [Homo sapiens]                               259   5e-69
gi|4502247 armadillo repeat protein [Homo sapiens]                    247   3e-65
gi|146231975 catenin, delta 1 isoform 3A [Homo sapiens]               230   3e-60
gi|146231948 catenin, delta 1 isoform 3A [Homo sapiens]               230   3e-60
gi|146231994 catenin, delta 1 isoform 3A [Homo sapiens]               230   3e-60
gi|146231946 catenin, delta 1 isoform 3B [Homo sapiens]               230   3e-60
gi|146231991 catenin, delta 1 isoform 3AB [Homo sapiens]              230   3e-60
gi|146231942 catenin, delta 1 isoform 1A [Homo sapiens]               230   3e-60
gi|146231968 catenin, delta 1 isoform 1A [Homo sapiens]               230   3e-60
gi|146231938 catenin, delta 1 isoform 1A [Homo sapiens]               230   3e-60
gi|10835010 catenin, delta 1 isoform 1B [Homo sapiens]                230   3e-60
gi|146231962 catenin, delta 1 isoform 1AB [Homo sapiens]              230   3e-60
gi|146231977 catenin, delta 1 isoform 3AC [Homo sapiens]              228   1e-59
gi|146231970 catenin, delta 1 isoform 3ABC [Homo sapiens]             228   1e-59
gi|146231940 catenin, delta 1 isoform 1ABC [Homo sapiens]             228   1e-59
gi|4504811 junction plakoglobin [Homo sapiens]                         46   1e-04
gi|12056468 junction plakoglobin [Homo sapiens]                        46   1e-04
gi|189011568 adenomatous polyposis coli [Homo sapiens]                 42   0.002
gi|189011566 adenomatous polyposis coli [Homo sapiens]                 42   0.002
gi|53759122 adenomatous polyposis coli [Homo sapiens]                  42   0.002
gi|189409124 armadillo repeat containing 3 [Homo sapiens]              42   0.002
gi|148227672 catenin (cadherin-associated protein), beta 1, 88kD...    41   0.004

>gi|53729344 plakophilin 1 isoform 1a [Homo sapiens]
          Length = 726

 Score = 1259 bits (3257), Expect = 0.0
 Identities = 625/625 (100%), Positives = 625/625 (100%)

Query: 1   PIYNGTLKREPDNRRFSSYSQMENWSRHYPRGSCNTTGAGSDICFMQKIKASRSEPDLYC 60
           PIYNGTLKREPDNRRFSSYSQMENWSRHYPRGSCNTTGAGSDICFMQKIKASRSEPDLYC
Sbjct: 102 PIYNGTLKREPDNRRFSSYSQMENWSRHYPRGSCNTTGAGSDICFMQKIKASRSEPDLYC 161

Query: 61  DPRGTLRKGTLGSKGQKTTQNRYSFYSTCSGQKAIKKCPVRPPSCASKQDPVYIPPISCN 120
           DPRGTLRKGTLGSKGQKTTQNRYSFYSTCSGQKAIKKCPVRPPSCASKQDPVYIPPISCN
Sbjct: 162 DPRGTLRKGTLGSKGQKTTQNRYSFYSTCSGQKAIKKCPVRPPSCASKQDPVYIPPISCN 221

Query: 121 KDLSFGHSRASSKICSEDIECSGLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQ 180
           KDLSFGHSRASSKICSEDIECSGLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQ
Sbjct: 222 KDLSFGHSRASSKICSEDIECSGLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQ 281

Query: 181 QVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLETRRQNGIREAVSLLRRT 240
           QVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLETRRQNGIREAVSLLRRT
Sbjct: 282 QVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLETRRQNGIREAVSLLRRT 341

Query: 241 GNAEIQKQLTGLLWNLSSTDELKEELIADALPVLADRVIIPFSGWCDGNSNMSREVVDPE 300
           GNAEIQKQLTGLLWNLSSTDELKEELIADALPVLADRVIIPFSGWCDGNSNMSREVVDPE
Sbjct: 342 GNAEIQKQLTGLLWNLSSTDELKEELIADALPVLADRVIIPFSGWCDGNSNMSREVVDPE 401

Query: 301 VFFNATGCLRNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNL 360
           VFFNATGCLRNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNL
Sbjct: 402 VFFNATGCLRNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNL 461

Query: 361 SYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGW 420
           SYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGW
Sbjct: 462 SYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGW 521

Query: 421 LYHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIAR 480
           LYHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIAR
Sbjct: 522 LYHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIAR 581

Query: 481 LLQSGNSDVVRSGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSAC 540
           LLQSGNSDVVRSGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSAC
Sbjct: 582 LLQSGNSDVVRSGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSAC 641

Query: 541 YTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWSSKELQGVLR 600
           YTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWSSKELQGVLR
Sbjct: 642 YTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWSSKELQGVLR 701

Query: 601 QQGFDRNMLGTLAGANSLRNFTSRF 625
           QQGFDRNMLGTLAGANSLRNFTSRF
Sbjct: 702 QQGFDRNMLGTLAGANSLRNFTSRF 726


>gi|169218113 PREDICTED: similar to plakophilin 1, partial [Homo
           sapiens]
          Length = 625

 Score = 1259 bits (3257), Expect = 0.0
 Identities = 625/625 (100%), Positives = 625/625 (100%)

Query: 1   PIYNGTLKREPDNRRFSSYSQMENWSRHYPRGSCNTTGAGSDICFMQKIKASRSEPDLYC 60
           PIYNGTLKREPDNRRFSSYSQMENWSRHYPRGSCNTTGAGSDICFMQKIKASRSEPDLYC
Sbjct: 1   PIYNGTLKREPDNRRFSSYSQMENWSRHYPRGSCNTTGAGSDICFMQKIKASRSEPDLYC 60

Query: 61  DPRGTLRKGTLGSKGQKTTQNRYSFYSTCSGQKAIKKCPVRPPSCASKQDPVYIPPISCN 120
           DPRGTLRKGTLGSKGQKTTQNRYSFYSTCSGQKAIKKCPVRPPSCASKQDPVYIPPISCN
Sbjct: 61  DPRGTLRKGTLGSKGQKTTQNRYSFYSTCSGQKAIKKCPVRPPSCASKQDPVYIPPISCN 120

Query: 121 KDLSFGHSRASSKICSEDIECSGLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQ 180
           KDLSFGHSRASSKICSEDIECSGLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQ
Sbjct: 121 KDLSFGHSRASSKICSEDIECSGLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQ 180

Query: 181 QVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLETRRQNGIREAVSLLRRT 240
           QVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLETRRQNGIREAVSLLRRT
Sbjct: 181 QVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLETRRQNGIREAVSLLRRT 240

Query: 241 GNAEIQKQLTGLLWNLSSTDELKEELIADALPVLADRVIIPFSGWCDGNSNMSREVVDPE 300
           GNAEIQKQLTGLLWNLSSTDELKEELIADALPVLADRVIIPFSGWCDGNSNMSREVVDPE
Sbjct: 241 GNAEIQKQLTGLLWNLSSTDELKEELIADALPVLADRVIIPFSGWCDGNSNMSREVVDPE 300

Query: 301 VFFNATGCLRNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNL 360
           VFFNATGCLRNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNL
Sbjct: 301 VFFNATGCLRNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNL 360

Query: 361 SYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGW 420
           SYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGW
Sbjct: 361 SYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGW 420

Query: 421 LYHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIAR 480
           LYHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIAR
Sbjct: 421 LYHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIAR 480

Query: 481 LLQSGNSDVVRSGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSAC 540
           LLQSGNSDVVRSGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSAC
Sbjct: 481 LLQSGNSDVVRSGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSAC 540

Query: 541 YTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWSSKELQGVLR 600
           YTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWSSKELQGVLR
Sbjct: 541 YTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWSSKELQGVLR 600

Query: 601 QQGFDRNMLGTLAGANSLRNFTSRF 625
           QQGFDRNMLGTLAGANSLRNFTSRF
Sbjct: 601 QQGFDRNMLGTLAGANSLRNFTSRF 625


>gi|53729346 plakophilin 1 isoform 1b [Homo sapiens]
          Length = 747

 Score = 1246 bits (3225), Expect = 0.0
 Identities = 625/646 (96%), Positives = 625/646 (96%), Gaps = 21/646 (3%)

Query: 1   PIYNGTLKREPDNRRFSSYSQMENWSRHYPRGSCNTTGAGSDICFMQKIKASRSEPDLYC 60
           PIYNGTLKREPDNRRFSSYSQMENWSRHYPRGSCNTTGAGSDICFMQKIKASRSEPDLYC
Sbjct: 102 PIYNGTLKREPDNRRFSSYSQMENWSRHYPRGSCNTTGAGSDICFMQKIKASRSEPDLYC 161

Query: 61  DPRGTLRKGTLGSKGQKTTQNRYSFYSTCSGQKAIKKCPVRPPSCASKQDPVYIPPISCN 120
           DPRGTLRKGTLGSKGQKTTQNRYSFYSTCSGQKAIKKCPVRPPSCASKQDPVYIPPISCN
Sbjct: 162 DPRGTLRKGTLGSKGQKTTQNRYSFYSTCSGQKAIKKCPVRPPSCASKQDPVYIPPISCN 221

Query: 121 KDLSFGHSRASSKICSEDIECSGLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQ 180
           KDLSFGHSRASSKICSEDIECSGLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQ
Sbjct: 222 KDLSFGHSRASSKICSEDIECSGLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQ 281

Query: 181 QVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLETRRQNGIREAVSLLRRT 240
           QVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLETRRQNGIREAVSLLRRT
Sbjct: 282 QVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLETRRQNGIREAVSLLRRT 341

Query: 241 GNAEIQKQLTGLLWNLSSTDELKEELIADALPVLADRVIIPFSGWCDGNSNMSREVVDPE 300
           GNAEIQKQLTGLLWNLSSTDELKEELIADALPVLADRVIIPFSGWCDGNSNMSREVVDPE
Sbjct: 342 GNAEIQKQLTGLLWNLSSTDELKEELIADALPVLADRVIIPFSGWCDGNSNMSREVVDPE 401

Query: 301 VFFNATGCLR---------------------NLSSADAGRQTMRNYSGLIDSLMAYVQNC 339
           VFFNATGCLR                     NLSSADAGRQTMRNYSGLIDSLMAYVQNC
Sbjct: 402 VFFNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNC 461

Query: 340 VAASRCDDKSVENCMCVLHNLSYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKM 399
           VAASRCDDKSVENCMCVLHNLSYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKM
Sbjct: 462 VAASRCDDKSVENCMCVLHNLSYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKM 521

Query: 400 MNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGL 459
           MNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGL
Sbjct: 522 MNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGL 581

Query: 460 MSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPLLHRVMGNQVFPEVT 519
           MSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPLLHRVMGNQVFPEVT
Sbjct: 582 MSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPLLHRVMGNQVFPEVT 641

Query: 520 RLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAA 579
           RLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAA
Sbjct: 642 RLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAA 701

Query: 580 EAARLLLSDMWSSKELQGVLRQQGFDRNMLGTLAGANSLRNFTSRF 625
           EAARLLLSDMWSSKELQGVLRQQGFDRNMLGTLAGANSLRNFTSRF
Sbjct: 702 EAARLLLSDMWSSKELQGVLRQQGFDRNMLGTLAGANSLRNFTSRF 747


>gi|148664186 plakophilin 2 isoform 2a [Homo sapiens]
          Length = 837

 Score =  362 bits (930), Expect = e-100
 Identities = 198/482 (41%), Positives = 300/482 (62%), Gaps = 10/482 (2%)

Query: 132 SKICSEDIECSGLTIPKAVQYLSSQDEKYQAIGAY--YIQHTCFQDESAKQQVYQLGGIC 189
           S++ + D+E   +T+ +AV  L +       I A   +IQH CFQ   A+++V QL GI 
Sbjct: 342 SQLGNADME---MTLERAVSMLEADHMLPSRISAAATFIQHECFQKSEARKRVNQLRGIL 398

Query: 190 KLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLETRRQNGIREAVSLLRRTGNAEIQKQL 249
           KL+ LL+  N++VQ+A  GALRNLVF    NKLE    NG+   + +L++T + E +KQ+
Sbjct: 399 KLLQLLKVQNEDVQRAVCGALRNLVFEDNDNKLEVAELNGVPRLLQVLKQTRDLETKKQI 458

Query: 250 TGLLWNLSSTDELKEELIADALPVLADRVIIPFSGWCDGNSNMSREVVDPEVFFNATGCL 309
           TGLLWNLSS D+LK  +I +AL  L + +IIPFSGW +G+   +  ++D ++F+N TGCL
Sbjct: 459 TGLLWNLSSNDKLKNLMITEALLTLTENIIIPFSGWPEGDYPKANGLLDFDIFYNVTGCL 518

Query: 310 RNLSSADA-GRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLSYRLDAEV 368
           RN+SSA A GR+ MR   GLIDSL+ YV+  +A  + DDK+ ENC+C+LHNLSY+L+AE+
Sbjct: 519 RNMSSAGADGRKAMRRCDGLIDSLVHYVRGTIADYQPDDKATENCVCILHNLSYQLEAEL 578

Query: 369 PTRYRQLEY-NARNAYTEKS-STGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDA 426
           P +Y Q  Y   RN  T+ + S GCF ++S K+     D P+PEE++NPKG  WL+HS  
Sbjct: 579 PEKYSQNIYIQNRNIQTDNNKSIGCFGSRSRKVKEQYQDVPMPEEKSNPKGVEWLWHSIV 638

Query: 427 IRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGN 486
           IR YL+L+ KS ++ T EA  GALQNLTA  G M + ++Q +  KE GL    ++L  G+
Sbjct: 639 IRMYLSLIAKSVRNYTQEASLGALQNLTAGSGPMPTSVAQTVVQKESGLQHTRKMLHVGD 698

Query: 487 SDVVRSGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNL 546
             V ++  SLL N+SR+  L   +  +  P++  ++     +T    +  +SACYT+ N+
Sbjct: 699 PSVKKTAISLLRNLSRNLSLQNEIAKETLPDLVSIIPDTVPSTDLLIETTASACYTLNNI 758

Query: 547 MASQPQLAKQYFSSSMLNNIINLCRSS--ASPKAAEAARLLLSDMWSSKELQGVLRQQGF 604
           + +  Q A+   ++  +  I+ +      AS KA++AA +LL  +W+  EL    ++  F
Sbjct: 759 IQNSYQNARDLLNTGGIQKIMAISAGDAYASNKASKAASVLLYSLWAHTELHHAYKKAQF 818

Query: 605 DR 606
            +
Sbjct: 819 KK 820


>gi|148664226 plakophilin 2 isoform 2b [Homo sapiens]
          Length = 881

 Score =  341 bits (875), Expect = 1e-93
 Identities = 198/526 (37%), Positives = 300/526 (57%), Gaps = 54/526 (10%)

Query: 132 SKICSEDIECSGLTIPKAVQYLSSQDEKYQAIGAY--YIQHTCFQDESAKQQVYQLGGIC 189
           S++ + D+E   +T+ +AV  L +       I A   +IQH CFQ   A+++V QL GI 
Sbjct: 342 SQLGNADME---MTLERAVSMLEADHMLPSRISAAATFIQHECFQKSEARKRVNQLRGIL 398

Query: 190 KLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLETRRQNGIREAVSLLRRTGNAEIQKQL 249
           KL+ LL+  N++VQ+A  GALRNLVF    NKLE    NG+   + +L++T + E +KQ+
Sbjct: 399 KLLQLLKVQNEDVQRAVCGALRNLVFEDNDNKLEVAELNGVPRLLQVLKQTRDLETKKQI 458

Query: 250 T--------------------------------------------GLLWNLSSTDELKEE 265
           T                                            GLLWNLSS D+LK  
Sbjct: 459 TDHTVNLRSRNGWPGAVAHACNPSTLGGQGGRITRSGVRDQPDQHGLLWNLSSNDKLKNL 518

Query: 266 LIADALPVLADRVIIPFSGWCDGNSNMSREVVDPEVFFNATGCLRNLSSADA-GRQTMRN 324
           +I +AL  L + +IIPFSGW +G+   +  ++D ++F+N TGCLRN+SSA A GR+ MR 
Sbjct: 519 MITEALLTLTENIIIPFSGWPEGDYPKANGLLDFDIFYNVTGCLRNMSSAGADGRKAMRR 578

Query: 325 YSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLSYRLDAEVPTRYRQLEY-NARNAY 383
             GLIDSL+ YV+  +A  + DDK+ ENC+C+LHNLSY+L+AE+P +Y Q  Y   RN  
Sbjct: 579 CDGLIDSLVHYVRGTIADYQPDDKATENCVCILHNLSYQLEAELPEKYSQNIYIQNRNIQ 638

Query: 384 TEKS-STGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSKKDAT 442
           T+ + S GCF ++S K+     D P+PEE++NPKG  WL+HS  IR YL+L+ KS ++ T
Sbjct: 639 TDNNKSIGCFGSRSRKVKEQYQDVPMPEEKSNPKGVEWLWHSIVIRMYLSLIAKSVRNYT 698

Query: 443 LEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSR 502
            EA  GALQNLTA  G M + ++Q +  KE GL    ++L  G+  V ++  SLL N+SR
Sbjct: 699 QEASLGALQNLTAGSGPMPTSVAQTVVQKESGLQHTRKMLHVGDPSVKKTAISLLRNLSR 758

Query: 503 HPLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSM 562
           +  L   +  +  P++  ++     +T    +  +SACYT+ N++ +  Q A+   ++  
Sbjct: 759 NLSLQNEIAKETLPDLVSIIPDTVPSTDLLIETTASACYTLNNIIQNSYQNARDLLNTGG 818

Query: 563 LNNIINLCRSS--ASPKAAEAARLLLSDMWSSKELQGVLRQQGFDR 606
           +  I+ +      AS KA++AA +LL  +W+  EL    ++  F +
Sbjct: 819 IQKIMAISAGDAYASNKASKAASVLLYSLWAHTELHHAYKKAQFKK 864


>gi|53829376 plakophilin 4 isoform b [Homo sapiens]
          Length = 1149

 Score =  273 bits (697), Expect = 5e-73
 Identities = 168/482 (34%), Positives = 262/482 (54%), Gaps = 22/482 (4%)

Query: 146  IPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQA 205
            +P+ +  L  Q    QA  A Y+QH CF D   K +V +LGGI  LVDLL      VQ+ 
Sbjct: 530  LPEVIHMLQHQFPSVQANAAAYLQHLCFGDNKVKMEVCRLGGIKHLVDLLDHRVLEVQKN 589

Query: 206  AAGALRNLVFRSTT--NKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELK 263
            A GALRNLVF  +T  NK+  +   GI   + LLR++ +AE+++ +TG+LWNLSS D +K
Sbjct: 590  ACGALRNLVFGKSTDENKIAMKNVGGIPALLRLLRKSIDAEVRELVTGVLWNLSSCDAVK 649

Query: 264  EELIADALPVLADRVIIPFSGWCDGNSNMSREV--VDPEVFFNATGCLRNLSSA-DAGRQ 320
              +I DAL  L + VI+P SGW + + +   ++      V  N TGCLRNLSSA +  R+
Sbjct: 650  MTIIRDALSTLTNTVIVPHSGWNNSSFDDDHKIKFQTSLVLRNTTGCLRNLSSAGEEARK 709

Query: 321  TMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLSYRLDAEVPTRYRQLEYN-- 378
             MR+  GL+DSL+  +  CV  S  D K+VENC+C L NLSYRL+ EVP + R L  N  
Sbjct: 710  QMRSCEGLVDSLLYVIHTCVNTSDYDSKTVENCVCTLRNLSYRLELEVP-QARLLGLNEL 768

Query: 379  ----ARNAYTEKSSTGCFSNKSDKMMNNNYD------CPLPEEETNPKGSGWLYHSDAIR 428
                 + + ++ S   C+  K  K      +       P+P    +PKG   L+H   ++
Sbjct: 769  DDLLGKESPSKDSEPSCWGKKKKKKKRTPQEDQWDGVGPIPGLSKSPKGVEMLWHPSVVK 828

Query: 429  TYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSD 488
             YL L+ +S   ATLE  AG+LQNL+A     ++ +   +  KEKGLP +  LL+  N  
Sbjct: 829  PYLTLLAESSNPATLEGSAGSLQNLSAGNWKFAAYIRAAV-RKEKGLPILVELLRMDNDR 887

Query: 489  VVRSGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMA 548
            VV S A+ L NM+       ++G     ++   L    G +  S++ +++ C  +  + +
Sbjct: 888  VVSSVATALRNMALDVRNKELIGKYAMRDLVNRLPGGNGPSVLSDETMAAICCALHEVTS 947

Query: 549  SQPQLAKQYFSSSMLNNIINLCR---SSASPKAAEAARLLLSDMWSSKELQGVLRQQGFD 605
               + AK    S  +  ++N+ +     +S K  +AA  +L+ +W  ++L+ + ++ G++
Sbjct: 948  KNMENAKALADSGGIEKLVNITKGRGDRSSLKVVKAAAQVLNTLWQYRDLRSIYKKDGWN 1007

Query: 606  RN 607
            +N
Sbjct: 1008 QN 1009


>gi|53829374 plakophilin 4 isoform a [Homo sapiens]
          Length = 1192

 Score =  273 bits (697), Expect = 5e-73
 Identities = 168/482 (34%), Positives = 262/482 (54%), Gaps = 22/482 (4%)

Query: 146  IPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQA 205
            +P+ +  L  Q    QA  A Y+QH CF D   K +V +LGGI  LVDLL      VQ+ 
Sbjct: 530  LPEVIHMLQHQFPSVQANAAAYLQHLCFGDNKVKMEVCRLGGIKHLVDLLDHRVLEVQKN 589

Query: 206  AAGALRNLVFRSTT--NKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELK 263
            A GALRNLVF  +T  NK+  +   GI   + LLR++ +AE+++ +TG+LWNLSS D +K
Sbjct: 590  ACGALRNLVFGKSTDENKIAMKNVGGIPALLRLLRKSIDAEVRELVTGVLWNLSSCDAVK 649

Query: 264  EELIADALPVLADRVIIPFSGWCDGNSNMSREV--VDPEVFFNATGCLRNLSSA-DAGRQ 320
              +I DAL  L + VI+P SGW + + +   ++      V  N TGCLRNLSSA +  R+
Sbjct: 650  MTIIRDALSTLTNTVIVPHSGWNNSSFDDDHKIKFQTSLVLRNTTGCLRNLSSAGEEARK 709

Query: 321  TMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLSYRLDAEVPTRYRQLEYN-- 378
             MR+  GL+DSL+  +  CV  S  D K+VENC+C L NLSYRL+ EVP + R L  N  
Sbjct: 710  QMRSCEGLVDSLLYVIHTCVNTSDYDSKTVENCVCTLRNLSYRLELEVP-QARLLGLNEL 768

Query: 379  ----ARNAYTEKSSTGCFSNKSDKMMNNNYD------CPLPEEETNPKGSGWLYHSDAIR 428
                 + + ++ S   C+  K  K      +       P+P    +PKG   L+H   ++
Sbjct: 769  DDLLGKESPSKDSEPSCWGKKKKKKKRTPQEDQWDGVGPIPGLSKSPKGVEMLWHPSVVK 828

Query: 429  TYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSD 488
             YL L+ +S   ATLE  AG+LQNL+A     ++ +   +  KEKGLP +  LL+  N  
Sbjct: 829  PYLTLLAESSNPATLEGSAGSLQNLSAGNWKFAAYIRAAV-RKEKGLPILVELLRMDNDR 887

Query: 489  VVRSGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMA 548
            VV S A+ L NM+       ++G     ++   L    G +  S++ +++ C  +  + +
Sbjct: 888  VVSSVATALRNMALDVRNKELIGKYAMRDLVNRLPGGNGPSVLSDETMAAICCALHEVTS 947

Query: 549  SQPQLAKQYFSSSMLNNIINLCR---SSASPKAAEAARLLLSDMWSSKELQGVLRQQGFD 605
               + AK    S  +  ++N+ +     +S K  +AA  +L+ +W  ++L+ + ++ G++
Sbjct: 948  KNMENAKALADSGGIEKLVNITKGRGDRSSLKVVKAAAQVLNTLWQYRDLRSIYKKDGWN 1007

Query: 606  RN 607
            +N
Sbjct: 1008 QN 1009


>gi|11034811 catenin (cadherin-associated protein), delta 2 (neural
            plakophilin-related arm-repeat protein) [Homo sapiens]
          Length = 1225

 Score =  263 bits (673), Expect = 3e-70
 Identities = 170/487 (34%), Positives = 261/487 (53%), Gaps = 31/487 (6%)

Query: 146  IPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQA 205
            +P+ +Q L  Q    Q+  A Y+QH CF D   K ++ + GGI  LVDLL      V ++
Sbjct: 552  LPEVIQMLQHQFPSVQSNAAAYLQHLCFGDNKIKAEIRRQGGIQLLVDLLDHRMTEVHRS 611

Query: 206  AAGALRNLVFRSTT--NKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELK 263
            A GALRNLV+      NK+  +   GI   V LLR+T + EI++ +TG+LWNLSS D LK
Sbjct: 612  ACGALRNLVYGKANDDNKIALKNCGGIPALVRLLRKTTDLEIRELVTGVLWNLSSCDALK 671

Query: 264  EELIADALPVLADRVIIPFSGWCDGNSNMSREVV--DPEVFFNATGCLRNLSSA-DAGRQ 320
              +I DAL VL + VIIP SGW +      R++     +V  NATGCLRN+SSA +  R+
Sbjct: 672  MPIIQDALAVLTNAVIIPHSGWENSPLQDDRKIQLHSSQVLRNATGCLRNVSSAGEEARR 731

Query: 321  TMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLSYRLDAEVPTRYRQ------ 374
             MR   GL D+L+  +Q+ + +S  D K+VENC+C+L NLSYRL AE             
Sbjct: 732  RMRECDGLTDALLYVIQSALGSSEIDSKTVENCVCILRNLSYRLAAETSQGQHMGTDELD 791

Query: 375  ----LEYNARNAYTEKSSTGCFSNKSDKMMN-NNYD--CPLPEEETNPKGSGWLYHSDAI 427
                 E N ++A     S+GC+  K  K  + + +D   PLP+    PKG   L+H   +
Sbjct: 792  GLLCGEANGKDA----ESSGCWGKKKKKKKSQDQWDGVGPLPDCAEPPKGIQMLWHPSIV 847

Query: 428  RTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNS 487
            + YL L+ +     TLE  AGALQNL A     S  +   +  KEKGLP +  LL+  N 
Sbjct: 848  KPYLTLLSECSNPDTLEGAAGALQNLAAGSWKWSVYIRAAV-RKEKGLPILVELLRIDND 906

Query: 488  DVVRSGASLLSNMSRHPLLHRVMGNQVFPEVTRLL-----TSHTGNTSNSEDILSSACYT 542
             VV + A+ L NM+       ++G     ++   L     +++T + + S+D +++ C T
Sbjct: 907  RVVCAVATALRNMALDVRNKELIGKYAMRDLVHRLPGGNNSNNTASKAMSDDTVTAVCCT 966

Query: 543  VRNLMASQPQLAKQYFSSSMLNNIINLCRSSA---SPKAAEAARLLLSDMWSSKELQGVL 599
            +  ++    + AK    +  +  ++ + +S     SPK  +AA  +L+ MW  ++L+ + 
Sbjct: 967  LHEVITKNMENAKALRDAGGIEKLVGISKSKGDKHSPKVVKAASQVLNSMWQYRDLRSLY 1026

Query: 600  RQQGFDR 606
            ++ G+ +
Sbjct: 1027 KKDGWSQ 1033


>gi|6005830 plakophilin 3 [Homo sapiens]
          Length = 797

 Score =  259 bits (662), Expect = 5e-69
 Identities = 172/499 (34%), Positives = 265/499 (53%), Gaps = 29/499 (5%)

Query: 124 SFGHSRASSKICS--EDIECSGLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQ 181
           S+G  R   ++ S  +DI+     +P AV+YL + D   Q +GA YIQH C+ D +AK+Q
Sbjct: 302 SYGSHRTLQRLSSGFDDID-----LPSAVKYLMASDPNLQVLGAAYIQHKCYSDAAAKKQ 356

Query: 182 VYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLETRRQNGIREAVSLLRRTG 241
              L  + +LV L    NQ VQ+ A GA+RNL++ +  NKL    +NGI E +  LR   
Sbjct: 357 ARSLQAVPRLVKLFNHANQEVQRHATGAMRNLIYDNADNKLALVEENGIFELLRTLREQD 416

Query: 242 NAEIQKQLTGLLWNLSSTDELKEELIADALPVLADRVIIPFSGWCDGNSNMSREVVDPEV 301
           + E++K +TG+LWNLSS+D LK+ L  D L  L D V+ P SG   G   + +   + E+
Sbjct: 417 D-ELRKNVTGILWNLSSSDHLKDRLARDTLEQLTDLVLSPLSG-AGGPPLIQQNASEAEI 474

Query: 302 FFNATGCLRNLSSA-DAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNL 360
           F+NATG LRNLSSA  A RQ MR   GL+D+L+  + + + A +C+DKSVEN +CVL NL
Sbjct: 475 FYNATGFLRNLSSASQATRQKMRECHGLVDALVTSINHALDAGKCEDKSVENAVCVLRNL 534

Query: 361 SYRL-DAEVPTRYRQLEYNARN---AYTEKSSTGCFSNKSDKMMNNNYDCPL-------P 409
           SYRL D   P+  ++LE   R            GCF+ +S ++     + PL        
Sbjct: 535 SYRLYDEMPPSALQRLEGRGRRDLAGAPPGEVVGCFTPQSRRLR----ELPLAADALTFA 590

Query: 410 EEETNPKGSGWLYHSDAIRTYLNLMGKSKKDA-TLEACAGALQNLTASKGLMSSGMSQLI 468
           E   +PKG  WL+    +  Y  L+ + + +  T EA AGALQN+TA     +  +S+L 
Sbjct: 591 EVSKDPKGLEWLWSPQIVGLYNRLLQRCELNRHTTEAAAGALQNITAGDRRWAGVLSRLA 650

Query: 469 GLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGN 528
             +E+ L  +   +++ +   +RS   L+ N+SR+      M  +V   +   L    G 
Sbjct: 651 LEQERILNPLLDRVRTADHHQLRSLTGLIRNLSRNARNKDEMSTKVVSHLIEKLPGSVGE 710

Query: 529 TSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASP---KAAEAARLL 585
            S   ++L +    + NL+ + P  A+       L  +I + +   SP   K++ AA  L
Sbjct: 711 KSPPAEVLVNIIAVLNNLVVASPIAARDLLYFDGLRKLIFIKKKRDSPDSEKSSRAASSL 770

Query: 586 LSDMWSSKELQGVLRQQGF 604
           L+++W   +L    R +G+
Sbjct: 771 LANLWQYNKLHRDFRAKGY 789


>gi|4502247 armadillo repeat protein [Homo sapiens]
          Length = 962

 Score =  247 bits (630), Expect = 3e-65
 Identities = 167/489 (34%), Positives = 255/489 (52%), Gaps = 30/489 (6%)

Query: 146 IPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQA 205
           +P+ +  L    +  +A  A Y+QH CF++E  K++V QL G+  LV LL  P   V++ 
Sbjct: 360 LPEVLAMLRHPVDPVKANAAAYLQHLCFENEGVKRRVRQLRGLPLLVALLDHPRAEVRRR 419

Query: 206 AAGALRNLVF-RSTTNKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKE 264
           A GALRNL + R T NK   R   G+   V LLR   + E+++ +TG LWNLSS + LK 
Sbjct: 420 ACGALRNLSYGRDTDNKAAIRDCGGVPALVRLLRAARDNEVRELVTGTLWNLSSYEPLKM 479

Query: 265 ELIADALPVLADRVIIPFSGWCDGNSNMSREVVDPE---VFFNATGCLRNLSSADA-GRQ 320
            +I   L  L   VI+P SGW +   N   +  D E   VF N +GCLRN+SS  A  R+
Sbjct: 480 VIIDHGLQTLTHEVIVPHSGW-EREPNEDSKPRDAEWTTVFKNTSGCLRNVSSDGAEARR 538

Query: 321 TMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLSYRLDAEVP--TRYRQLEYN 378
            +R   GL+D+L+  +Q+ V     D+KSVENC+C++ NLSY +  EVP   RY++ E  
Sbjct: 539 RLRECEGLVDALLHALQSAVGRKDTDNKSVENCVCIMRNLSYHVHKEVPGADRYQEAEPG 598

Query: 379 ARNAYT-----EKSSTGCF-----------SNKSDKMMNNNYD-CPLPEEETNPKGSGWL 421
              +        +    CF             K D  M+ N+D   LP+     KG   L
Sbjct: 599 PLGSAVGSQRRRRDDASCFGGKKAKEEWFHQGKKDGEMDRNFDTLDLPKRTEAAKGFELL 658

Query: 422 YHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARL 481
           Y  + +R YL+L+ +S+   TLEA AGALQNL+A   + ++ +   +  KE+GLP +  L
Sbjct: 659 YQPEVVRLYLSLLTESRNFNTLEAAAGALQNLSAGNWMWATYIRATV-RKERGLPVLVEL 717

Query: 482 LQSGNSDVVRSGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTG----NTSNSEDILS 537
           LQS    VVR+ A  L N+S       ++G+    E+ R + +            ED + 
Sbjct: 718 LQSETDKVVRAVAIALRNLSLDRRNKDLIGSYAMAELVRNVRNAQAPPRPGACLEEDTVV 777

Query: 538 SACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWSSKELQG 597
           +   T+  +++     A+    +  +  ++ L  SS S + A+AA  +L  +WS KEL+G
Sbjct: 778 AVLNTIHEIVSDSLDNARSLLQARGVPALVALVASSQSVREAKAASHVLQTVWSYKELRG 837

Query: 598 VLRQQGFDR 606
            L++ G+ +
Sbjct: 838 TLQKDGWTK 846


>gi|146231975 catenin, delta 1 isoform 3A [Homo sapiens]
          Length = 832

 Score =  230 bits (587), Expect = 3e-60
 Identities = 156/479 (32%), Positives = 252/479 (52%), Gaps = 22/479 (4%)

Query: 146 IPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQA 205
           +P+ +  L  + +  ++  A Y+QH C++++  K  V +L GI  LV LL  P + V   
Sbjct: 267 LPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLG 326

Query: 206 AAGALRNLVF-RSTTNKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKE 264
           A GAL+N+ F R   NK+  +  +G+   V LLR+  + ++ + +TG LWNLSS D +K 
Sbjct: 327 ACGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSHDSIKM 386

Query: 265 ELIADALPVLADRVIIPFSGW-CDGNSNMS-REVVDPEVFFNATGCLRNLSS-ADAGRQT 321
           E++  AL  L D VIIP SGW  + N +   R +    V  N  GCLRN+SS     R+ 
Sbjct: 387 EIVDHALHALTDEVIIPHSGWEREPNEDCKPRHIEWESVLTNTAGCLRNVSSERSEARRK 446

Query: 322 MRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLSYRLDAEVP--TRYRQLEYNA 379
           +R   GL+D+L+  VQ  +     D K VENC+C+L NLSY++  E+P   RY++   N 
Sbjct: 447 LRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLRNLSYQVHREIPQAERYQEAAPNV 506

Query: 380 RNAYTEKSSTGCFSNKSDK-------MMNNNYDCPLPEEETNP-KGSGWLYHSDAIRTYL 431
            N  T   +  CF  K  K         N+  D P   + T+P +G   L+  + +R Y+
Sbjct: 507 AN-NTGPHAASCFGAKKGKGKKPIEDPANDTVDFP---KRTSPARGYELLFQPEVVRIYI 562

Query: 432 NLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVR 491
           +L+ +SK  A LEA AGA+QNL A +      +   +  +EK L  IA LL + +  VV+
Sbjct: 563 SLLKESKTPAILEASAGAIQNLCAGRWTYGRYIRSAL-RQEKALSAIADLLTNEHERVVK 621

Query: 492 SGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTS--NSEDILSSACYTVRNLMAS 549
           + +  L N++       ++G    P + + L     N+S   SED + S   T+  ++A 
Sbjct: 622 AASGALRNLAVDARNKELIGKHAIPNLVKNLPGGQQNSSWNFSEDTVISILNTINEVIAE 681

Query: 550 QPQLAKQYFSSSMLNNIINLCRS-SASPKAAEAARLLLSDMWSSKELQGVLRQQGFDRN 607
             + AK+   +  +  ++ + +S + S K   AA L+L  +W  KEL+  L ++G+ ++
Sbjct: 682 NLEAAKKLRETQGIEKLVLINKSGNRSEKEVRAAALVLQTIWGYKELRKPLEKEGWKKS 740


>gi|146231948 catenin, delta 1 isoform 3A [Homo sapiens]
          Length = 832

 Score =  230 bits (587), Expect = 3e-60
 Identities = 156/479 (32%), Positives = 252/479 (52%), Gaps = 22/479 (4%)

Query: 146 IPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQA 205
           +P+ +  L  + +  ++  A Y+QH C++++  K  V +L GI  LV LL  P + V   
Sbjct: 267 LPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLG 326

Query: 206 AAGALRNLVF-RSTTNKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKE 264
           A GAL+N+ F R   NK+  +  +G+   V LLR+  + ++ + +TG LWNLSS D +K 
Sbjct: 327 ACGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSHDSIKM 386

Query: 265 ELIADALPVLADRVIIPFSGW-CDGNSNMS-REVVDPEVFFNATGCLRNLSS-ADAGRQT 321
           E++  AL  L D VIIP SGW  + N +   R +    V  N  GCLRN+SS     R+ 
Sbjct: 387 EIVDHALHALTDEVIIPHSGWEREPNEDCKPRHIEWESVLTNTAGCLRNVSSERSEARRK 446

Query: 322 MRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLSYRLDAEVP--TRYRQLEYNA 379
           +R   GL+D+L+  VQ  +     D K VENC+C+L NLSY++  E+P   RY++   N 
Sbjct: 447 LRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLRNLSYQVHREIPQAERYQEAAPNV 506

Query: 380 RNAYTEKSSTGCFSNKSDK-------MMNNNYDCPLPEEETNP-KGSGWLYHSDAIRTYL 431
            N  T   +  CF  K  K         N+  D P   + T+P +G   L+  + +R Y+
Sbjct: 507 AN-NTGPHAASCFGAKKGKGKKPIEDPANDTVDFP---KRTSPARGYELLFQPEVVRIYI 562

Query: 432 NLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVR 491
           +L+ +SK  A LEA AGA+QNL A +      +   +  +EK L  IA LL + +  VV+
Sbjct: 563 SLLKESKTPAILEASAGAIQNLCAGRWTYGRYIRSAL-RQEKALSAIADLLTNEHERVVK 621

Query: 492 SGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTS--NSEDILSSACYTVRNLMAS 549
           + +  L N++       ++G    P + + L     N+S   SED + S   T+  ++A 
Sbjct: 622 AASGALRNLAVDARNKELIGKHAIPNLVKNLPGGQQNSSWNFSEDTVISILNTINEVIAE 681

Query: 550 QPQLAKQYFSSSMLNNIINLCRS-SASPKAAEAARLLLSDMWSSKELQGVLRQQGFDRN 607
             + AK+   +  +  ++ + +S + S K   AA L+L  +W  KEL+  L ++G+ ++
Sbjct: 682 NLEAAKKLRETQGIEKLVLINKSGNRSEKEVRAAALVLQTIWGYKELRKPLEKEGWKKS 740


>gi|146231994 catenin, delta 1 isoform 3A [Homo sapiens]
          Length = 832

 Score =  230 bits (587), Expect = 3e-60
 Identities = 156/479 (32%), Positives = 252/479 (52%), Gaps = 22/479 (4%)

Query: 146 IPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQA 205
           +P+ +  L  + +  ++  A Y+QH C++++  K  V +L GI  LV LL  P + V   
Sbjct: 267 LPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLG 326

Query: 206 AAGALRNLVF-RSTTNKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKE 264
           A GAL+N+ F R   NK+  +  +G+   V LLR+  + ++ + +TG LWNLSS D +K 
Sbjct: 327 ACGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSHDSIKM 386

Query: 265 ELIADALPVLADRVIIPFSGW-CDGNSNMS-REVVDPEVFFNATGCLRNLSS-ADAGRQT 321
           E++  AL  L D VIIP SGW  + N +   R +    V  N  GCLRN+SS     R+ 
Sbjct: 387 EIVDHALHALTDEVIIPHSGWEREPNEDCKPRHIEWESVLTNTAGCLRNVSSERSEARRK 446

Query: 322 MRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLSYRLDAEVP--TRYRQLEYNA 379
           +R   GL+D+L+  VQ  +     D K VENC+C+L NLSY++  E+P   RY++   N 
Sbjct: 447 LRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLRNLSYQVHREIPQAERYQEAAPNV 506

Query: 380 RNAYTEKSSTGCFSNKSDK-------MMNNNYDCPLPEEETNP-KGSGWLYHSDAIRTYL 431
            N  T   +  CF  K  K         N+  D P   + T+P +G   L+  + +R Y+
Sbjct: 507 AN-NTGPHAASCFGAKKGKGKKPIEDPANDTVDFP---KRTSPARGYELLFQPEVVRIYI 562

Query: 432 NLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVR 491
           +L+ +SK  A LEA AGA+QNL A +      +   +  +EK L  IA LL + +  VV+
Sbjct: 563 SLLKESKTPAILEASAGAIQNLCAGRWTYGRYIRSAL-RQEKALSAIADLLTNEHERVVK 621

Query: 492 SGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTS--NSEDILSSACYTVRNLMAS 549
           + +  L N++       ++G    P + + L     N+S   SED + S   T+  ++A 
Sbjct: 622 AASGALRNLAVDARNKELIGKHAIPNLVKNLPGGQQNSSWNFSEDTVISILNTINEVIAE 681

Query: 550 QPQLAKQYFSSSMLNNIINLCRS-SASPKAAEAARLLLSDMWSSKELQGVLRQQGFDRN 607
             + AK+   +  +  ++ + +S + S K   AA L+L  +W  KEL+  L ++G+ ++
Sbjct: 682 NLEAAKKLRETQGIEKLVLINKSGNRSEKEVRAAALVLQTIWGYKELRKPLEKEGWKKS 740


>gi|146231946 catenin, delta 1 isoform 3B [Homo sapiens]
          Length = 840

 Score =  230 bits (587), Expect = 3e-60
 Identities = 156/479 (32%), Positives = 252/479 (52%), Gaps = 22/479 (4%)

Query: 146 IPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQA 205
           +P+ +  L  + +  ++  A Y+QH C++++  K  V +L GI  LV LL  P + V   
Sbjct: 267 LPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLG 326

Query: 206 AAGALRNLVF-RSTTNKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKE 264
           A GAL+N+ F R   NK+  +  +G+   V LLR+  + ++ + +TG LWNLSS D +K 
Sbjct: 327 ACGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSHDSIKM 386

Query: 265 ELIADALPVLADRVIIPFSGW-CDGNSNMS-REVVDPEVFFNATGCLRNLSS-ADAGRQT 321
           E++  AL  L D VIIP SGW  + N +   R +    V  N  GCLRN+SS     R+ 
Sbjct: 387 EIVDHALHALTDEVIIPHSGWEREPNEDCKPRHIEWESVLTNTAGCLRNVSSERSEARRK 446

Query: 322 MRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLSYRLDAEVP--TRYRQLEYNA 379
           +R   GL+D+L+  VQ  +     D K VENC+C+L NLSY++  E+P   RY++   N 
Sbjct: 447 LRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLRNLSYQVHREIPQAERYQEAAPNV 506

Query: 380 RNAYTEKSSTGCFSNKSDK-------MMNNNYDCPLPEEETNP-KGSGWLYHSDAIRTYL 431
            N  T   +  CF  K  K         N+  D P   + T+P +G   L+  + +R Y+
Sbjct: 507 AN-NTGPHAASCFGAKKGKGKKPIEDPANDTVDFP---KRTSPARGYELLFQPEVVRIYI 562

Query: 432 NLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVR 491
           +L+ +SK  A LEA AGA+QNL A +      +   +  +EK L  IA LL + +  VV+
Sbjct: 563 SLLKESKTPAILEASAGAIQNLCAGRWTYGRYIRSAL-RQEKALSAIADLLTNEHERVVK 621

Query: 492 SGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTS--NSEDILSSACYTVRNLMAS 549
           + +  L N++       ++G    P + + L     N+S   SED + S   T+  ++A 
Sbjct: 622 AASGALRNLAVDARNKELIGKHAIPNLVKNLPGGQQNSSWNFSEDTVISILNTINEVIAE 681

Query: 550 QPQLAKQYFSSSMLNNIINLCRS-SASPKAAEAARLLLSDMWSSKELQGVLRQQGFDRN 607
             + AK+   +  +  ++ + +S + S K   AA L+L  +W  KEL+  L ++G+ ++
Sbjct: 682 NLEAAKKLRETQGIEKLVLINKSGNRSEKEVRAAALVLQTIWGYKELRKPLEKEGWKKS 740


>gi|146231991 catenin, delta 1 isoform 3AB [Homo sapiens]
          Length = 861

 Score =  230 bits (587), Expect = 3e-60
 Identities = 156/479 (32%), Positives = 252/479 (52%), Gaps = 22/479 (4%)

Query: 146 IPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQA 205
           +P+ +  L  + +  ++  A Y+QH C++++  K  V +L GI  LV LL  P + V   
Sbjct: 267 LPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLG 326

Query: 206 AAGALRNLVF-RSTTNKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKE 264
           A GAL+N+ F R   NK+  +  +G+   V LLR+  + ++ + +TG LWNLSS D +K 
Sbjct: 327 ACGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSHDSIKM 386

Query: 265 ELIADALPVLADRVIIPFSGW-CDGNSNMS-REVVDPEVFFNATGCLRNLSS-ADAGRQT 321
           E++  AL  L D VIIP SGW  + N +   R +    V  N  GCLRN+SS     R+ 
Sbjct: 387 EIVDHALHALTDEVIIPHSGWEREPNEDCKPRHIEWESVLTNTAGCLRNVSSERSEARRK 446

Query: 322 MRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLSYRLDAEVP--TRYRQLEYNA 379
           +R   GL+D+L+  VQ  +     D K VENC+C+L NLSY++  E+P   RY++   N 
Sbjct: 447 LRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLRNLSYQVHREIPQAERYQEAAPNV 506

Query: 380 RNAYTEKSSTGCFSNKSDK-------MMNNNYDCPLPEEETNP-KGSGWLYHSDAIRTYL 431
            N  T   +  CF  K  K         N+  D P   + T+P +G   L+  + +R Y+
Sbjct: 507 AN-NTGPHAASCFGAKKGKGKKPIEDPANDTVDFP---KRTSPARGYELLFQPEVVRIYI 562

Query: 432 NLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVR 491
           +L+ +SK  A LEA AGA+QNL A +      +   +  +EK L  IA LL + +  VV+
Sbjct: 563 SLLKESKTPAILEASAGAIQNLCAGRWTYGRYIRSAL-RQEKALSAIADLLTNEHERVVK 621

Query: 492 SGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTS--NSEDILSSACYTVRNLMAS 549
           + +  L N++       ++G    P + + L     N+S   SED + S   T+  ++A 
Sbjct: 622 AASGALRNLAVDARNKELIGKHAIPNLVKNLPGGQQNSSWNFSEDTVISILNTINEVIAE 681

Query: 550 QPQLAKQYFSSSMLNNIINLCRS-SASPKAAEAARLLLSDMWSSKELQGVLRQQGFDRN 607
             + AK+   +  +  ++ + +S + S K   AA L+L  +W  KEL+  L ++G+ ++
Sbjct: 682 NLEAAKKLRETQGIEKLVLINKSGNRSEKEVRAAALVLQTIWGYKELRKPLEKEGWKKS 740


>gi|146231942 catenin, delta 1 isoform 1A [Homo sapiens]
          Length = 933

 Score =  230 bits (587), Expect = 3e-60
 Identities = 156/479 (32%), Positives = 252/479 (52%), Gaps = 22/479 (4%)

Query: 146 IPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQA 205
           +P+ +  L  + +  ++  A Y+QH C++++  K  V +L GI  LV LL  P + V   
Sbjct: 368 LPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLG 427

Query: 206 AAGALRNLVF-RSTTNKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKE 264
           A GAL+N+ F R   NK+  +  +G+   V LLR+  + ++ + +TG LWNLSS D +K 
Sbjct: 428 ACGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSHDSIKM 487

Query: 265 ELIADALPVLADRVIIPFSGW-CDGNSNMS-REVVDPEVFFNATGCLRNLSS-ADAGRQT 321
           E++  AL  L D VIIP SGW  + N +   R +    V  N  GCLRN+SS     R+ 
Sbjct: 488 EIVDHALHALTDEVIIPHSGWEREPNEDCKPRHIEWESVLTNTAGCLRNVSSERSEARRK 547

Query: 322 MRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLSYRLDAEVP--TRYRQLEYNA 379
           +R   GL+D+L+  VQ  +     D K VENC+C+L NLSY++  E+P   RY++   N 
Sbjct: 548 LRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLRNLSYQVHREIPQAERYQEAAPNV 607

Query: 380 RNAYTEKSSTGCFSNKSDK-------MMNNNYDCPLPEEETNP-KGSGWLYHSDAIRTYL 431
            N  T   +  CF  K  K         N+  D P   + T+P +G   L+  + +R Y+
Sbjct: 608 AN-NTGPHAASCFGAKKGKGKKPIEDPANDTVDFP---KRTSPARGYELLFQPEVVRIYI 663

Query: 432 NLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVR 491
           +L+ +SK  A LEA AGA+QNL A +      +   +  +EK L  IA LL + +  VV+
Sbjct: 664 SLLKESKTPAILEASAGAIQNLCAGRWTYGRYIRSAL-RQEKALSAIADLLTNEHERVVK 722

Query: 492 SGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTS--NSEDILSSACYTVRNLMAS 549
           + +  L N++       ++G    P + + L     N+S   SED + S   T+  ++A 
Sbjct: 723 AASGALRNLAVDARNKELIGKHAIPNLVKNLPGGQQNSSWNFSEDTVISILNTINEVIAE 782

Query: 550 QPQLAKQYFSSSMLNNIINLCRS-SASPKAAEAARLLLSDMWSSKELQGVLRQQGFDRN 607
             + AK+   +  +  ++ + +S + S K   AA L+L  +W  KEL+  L ++G+ ++
Sbjct: 783 NLEAAKKLRETQGIEKLVLINKSGNRSEKEVRAAALVLQTIWGYKELRKPLEKEGWKKS 841


>gi|146231968 catenin, delta 1 isoform 1A [Homo sapiens]
          Length = 933

 Score =  230 bits (587), Expect = 3e-60
 Identities = 156/479 (32%), Positives = 252/479 (52%), Gaps = 22/479 (4%)

Query: 146 IPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQA 205
           +P+ +  L  + +  ++  A Y+QH C++++  K  V +L GI  LV LL  P + V   
Sbjct: 368 LPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLG 427

Query: 206 AAGALRNLVF-RSTTNKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKE 264
           A GAL+N+ F R   NK+  +  +G+   V LLR+  + ++ + +TG LWNLSS D +K 
Sbjct: 428 ACGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSHDSIKM 487

Query: 265 ELIADALPVLADRVIIPFSGW-CDGNSNMS-REVVDPEVFFNATGCLRNLSS-ADAGRQT 321
           E++  AL  L D VIIP SGW  + N +   R +    V  N  GCLRN+SS     R+ 
Sbjct: 488 EIVDHALHALTDEVIIPHSGWEREPNEDCKPRHIEWESVLTNTAGCLRNVSSERSEARRK 547

Query: 322 MRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLSYRLDAEVP--TRYRQLEYNA 379
           +R   GL+D+L+  VQ  +     D K VENC+C+L NLSY++  E+P   RY++   N 
Sbjct: 548 LRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLRNLSYQVHREIPQAERYQEAAPNV 607

Query: 380 RNAYTEKSSTGCFSNKSDK-------MMNNNYDCPLPEEETNP-KGSGWLYHSDAIRTYL 431
            N  T   +  CF  K  K         N+  D P   + T+P +G   L+  + +R Y+
Sbjct: 608 AN-NTGPHAASCFGAKKGKGKKPIEDPANDTVDFP---KRTSPARGYELLFQPEVVRIYI 663

Query: 432 NLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVR 491
           +L+ +SK  A LEA AGA+QNL A +      +   +  +EK L  IA LL + +  VV+
Sbjct: 664 SLLKESKTPAILEASAGAIQNLCAGRWTYGRYIRSAL-RQEKALSAIADLLTNEHERVVK 722

Query: 492 SGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTS--NSEDILSSACYTVRNLMAS 549
           + +  L N++       ++G    P + + L     N+S   SED + S   T+  ++A 
Sbjct: 723 AASGALRNLAVDARNKELIGKHAIPNLVKNLPGGQQNSSWNFSEDTVISILNTINEVIAE 782

Query: 550 QPQLAKQYFSSSMLNNIINLCRS-SASPKAAEAARLLLSDMWSSKELQGVLRQQGFDRN 607
             + AK+   +  +  ++ + +S + S K   AA L+L  +W  KEL+  L ++G+ ++
Sbjct: 783 NLEAAKKLRETQGIEKLVLINKSGNRSEKEVRAAALVLQTIWGYKELRKPLEKEGWKKS 841


>gi|146231938 catenin, delta 1 isoform 1A [Homo sapiens]
          Length = 933

 Score =  230 bits (587), Expect = 3e-60
 Identities = 156/479 (32%), Positives = 252/479 (52%), Gaps = 22/479 (4%)

Query: 146 IPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQA 205
           +P+ +  L  + +  ++  A Y+QH C++++  K  V +L GI  LV LL  P + V   
Sbjct: 368 LPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLG 427

Query: 206 AAGALRNLVF-RSTTNKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKE 264
           A GAL+N+ F R   NK+  +  +G+   V LLR+  + ++ + +TG LWNLSS D +K 
Sbjct: 428 ACGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSHDSIKM 487

Query: 265 ELIADALPVLADRVIIPFSGW-CDGNSNMS-REVVDPEVFFNATGCLRNLSS-ADAGRQT 321
           E++  AL  L D VIIP SGW  + N +   R +    V  N  GCLRN+SS     R+ 
Sbjct: 488 EIVDHALHALTDEVIIPHSGWEREPNEDCKPRHIEWESVLTNTAGCLRNVSSERSEARRK 547

Query: 322 MRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLSYRLDAEVP--TRYRQLEYNA 379
           +R   GL+D+L+  VQ  +     D K VENC+C+L NLSY++  E+P   RY++   N 
Sbjct: 548 LRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLRNLSYQVHREIPQAERYQEAAPNV 607

Query: 380 RNAYTEKSSTGCFSNKSDK-------MMNNNYDCPLPEEETNP-KGSGWLYHSDAIRTYL 431
            N  T   +  CF  K  K         N+  D P   + T+P +G   L+  + +R Y+
Sbjct: 608 AN-NTGPHAASCFGAKKGKGKKPIEDPANDTVDFP---KRTSPARGYELLFQPEVVRIYI 663

Query: 432 NLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVR 491
           +L+ +SK  A LEA AGA+QNL A +      +   +  +EK L  IA LL + +  VV+
Sbjct: 664 SLLKESKTPAILEASAGAIQNLCAGRWTYGRYIRSAL-RQEKALSAIADLLTNEHERVVK 722

Query: 492 SGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTS--NSEDILSSACYTVRNLMAS 549
           + +  L N++       ++G    P + + L     N+S   SED + S   T+  ++A 
Sbjct: 723 AASGALRNLAVDARNKELIGKHAIPNLVKNLPGGQQNSSWNFSEDTVISILNTINEVIAE 782

Query: 550 QPQLAKQYFSSSMLNNIINLCRS-SASPKAAEAARLLLSDMWSSKELQGVLRQQGFDRN 607
             + AK+   +  +  ++ + +S + S K   AA L+L  +W  KEL+  L ++G+ ++
Sbjct: 783 NLEAAKKLRETQGIEKLVLINKSGNRSEKEVRAAALVLQTIWGYKELRKPLEKEGWKKS 841


>gi|10835010 catenin, delta 1 isoform 1B [Homo sapiens]
          Length = 941

 Score =  230 bits (587), Expect = 3e-60
 Identities = 156/479 (32%), Positives = 252/479 (52%), Gaps = 22/479 (4%)

Query: 146 IPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQA 205
           +P+ +  L  + +  ++  A Y+QH C++++  K  V +L GI  LV LL  P + V   
Sbjct: 368 LPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLG 427

Query: 206 AAGALRNLVF-RSTTNKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKE 264
           A GAL+N+ F R   NK+  +  +G+   V LLR+  + ++ + +TG LWNLSS D +K 
Sbjct: 428 ACGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSHDSIKM 487

Query: 265 ELIADALPVLADRVIIPFSGW-CDGNSNMS-REVVDPEVFFNATGCLRNLSS-ADAGRQT 321
           E++  AL  L D VIIP SGW  + N +   R +    V  N  GCLRN+SS     R+ 
Sbjct: 488 EIVDHALHALTDEVIIPHSGWEREPNEDCKPRHIEWESVLTNTAGCLRNVSSERSEARRK 547

Query: 322 MRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLSYRLDAEVP--TRYRQLEYNA 379
           +R   GL+D+L+  VQ  +     D K VENC+C+L NLSY++  E+P   RY++   N 
Sbjct: 548 LRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLRNLSYQVHREIPQAERYQEAAPNV 607

Query: 380 RNAYTEKSSTGCFSNKSDK-------MMNNNYDCPLPEEETNP-KGSGWLYHSDAIRTYL 431
            N  T   +  CF  K  K         N+  D P   + T+P +G   L+  + +R Y+
Sbjct: 608 AN-NTGPHAASCFGAKKGKGKKPIEDPANDTVDFP---KRTSPARGYELLFQPEVVRIYI 663

Query: 432 NLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVR 491
           +L+ +SK  A LEA AGA+QNL A +      +   +  +EK L  IA LL + +  VV+
Sbjct: 664 SLLKESKTPAILEASAGAIQNLCAGRWTYGRYIRSAL-RQEKALSAIADLLTNEHERVVK 722

Query: 492 SGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTS--NSEDILSSACYTVRNLMAS 549
           + +  L N++       ++G    P + + L     N+S   SED + S   T+  ++A 
Sbjct: 723 AASGALRNLAVDARNKELIGKHAIPNLVKNLPGGQQNSSWNFSEDTVISILNTINEVIAE 782

Query: 550 QPQLAKQYFSSSMLNNIINLCRS-SASPKAAEAARLLLSDMWSSKELQGVLRQQGFDRN 607
             + AK+   +  +  ++ + +S + S K   AA L+L  +W  KEL+  L ++G+ ++
Sbjct: 783 NLEAAKKLRETQGIEKLVLINKSGNRSEKEVRAAALVLQTIWGYKELRKPLEKEGWKKS 841


>gi|146231962 catenin, delta 1 isoform 1AB [Homo sapiens]
          Length = 962

 Score =  230 bits (587), Expect = 3e-60
 Identities = 156/479 (32%), Positives = 252/479 (52%), Gaps = 22/479 (4%)

Query: 146 IPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQA 205
           +P+ +  L  + +  ++  A Y+QH C++++  K  V +L GI  LV LL  P + V   
Sbjct: 368 LPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLG 427

Query: 206 AAGALRNLVF-RSTTNKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKE 264
           A GAL+N+ F R   NK+  +  +G+   V LLR+  + ++ + +TG LWNLSS D +K 
Sbjct: 428 ACGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSHDSIKM 487

Query: 265 ELIADALPVLADRVIIPFSGW-CDGNSNMS-REVVDPEVFFNATGCLRNLSS-ADAGRQT 321
           E++  AL  L D VIIP SGW  + N +   R +    V  N  GCLRN+SS     R+ 
Sbjct: 488 EIVDHALHALTDEVIIPHSGWEREPNEDCKPRHIEWESVLTNTAGCLRNVSSERSEARRK 547

Query: 322 MRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLSYRLDAEVP--TRYRQLEYNA 379
           +R   GL+D+L+  VQ  +     D K VENC+C+L NLSY++  E+P   RY++   N 
Sbjct: 548 LRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLRNLSYQVHREIPQAERYQEAAPNV 607

Query: 380 RNAYTEKSSTGCFSNKSDK-------MMNNNYDCPLPEEETNP-KGSGWLYHSDAIRTYL 431
            N  T   +  CF  K  K         N+  D P   + T+P +G   L+  + +R Y+
Sbjct: 608 AN-NTGPHAASCFGAKKGKGKKPIEDPANDTVDFP---KRTSPARGYELLFQPEVVRIYI 663

Query: 432 NLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVR 491
           +L+ +SK  A LEA AGA+QNL A +      +   +  +EK L  IA LL + +  VV+
Sbjct: 664 SLLKESKTPAILEASAGAIQNLCAGRWTYGRYIRSAL-RQEKALSAIADLLTNEHERVVK 722

Query: 492 SGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTS--NSEDILSSACYTVRNLMAS 549
           + +  L N++       ++G    P + + L     N+S   SED + S   T+  ++A 
Sbjct: 723 AASGALRNLAVDARNKELIGKHAIPNLVKNLPGGQQNSSWNFSEDTVISILNTINEVIAE 782

Query: 550 QPQLAKQYFSSSMLNNIINLCRS-SASPKAAEAARLLLSDMWSSKELQGVLRQQGFDRN 607
             + AK+   +  +  ++ + +S + S K   AA L+L  +W  KEL+  L ++G+ ++
Sbjct: 783 NLEAAKKLRETQGIEKLVLINKSGNRSEKEVRAAALVLQTIWGYKELRKPLEKEGWKKS 841


>gi|146231977 catenin, delta 1 isoform 3AC [Homo sapiens]
          Length = 838

 Score =  228 bits (581), Expect = 1e-59
 Identities = 156/485 (32%), Positives = 252/485 (51%), Gaps = 28/485 (5%)

Query: 146 IPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQA 205
           +P+ +  L  + +  ++  A Y+QH C++++  K  V +L GI  LV LL  P + V   
Sbjct: 267 LPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLG 326

Query: 206 AAGALRNLVF-RSTTNKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKE 264
           A GAL+N+ F R   NK+  +  +G+   V LLR+  + ++ + +TG LWNLSS D +K 
Sbjct: 327 ACGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSHDSIKM 386

Query: 265 ELIADALPVLADRVIIPFSGW-CDGNSNMS-REVVDPEVFFNATGCLRNLSS-ADAGRQT 321
           E++  AL  L D VIIP SGW  + N +   R +    V  N  GCLRN+SS     R+ 
Sbjct: 387 EIVDHALHALTDEVIIPHSGWEREPNEDCKPRHIEWESVLTNTAGCLRNVSSERSEARRK 446

Query: 322 MRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLSYRLDAEVP--TRYRQLEYNA 379
           +R   GL+D+L+  VQ  +     D K VENC+C+L NLSY++  E+P   RY++   N 
Sbjct: 447 LRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLRNLSYQVHREIPQAERYQEAAPNV 506

Query: 380 RNAYTEKSSTGCFSNKSDK-------------MMNNNYDCPLPEEETNP-KGSGWLYHSD 425
            N  T   +  CF  K  K               N+  D P   + T+P +G   L+  +
Sbjct: 507 AN-NTGPHAASCFGAKKGKDEWFSRGKKPIEDPANDTVDFP---KRTSPARGYELLFQPE 562

Query: 426 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSG 485
            +R Y++L+ +SK  A LEA AGA+QNL A +      +   +  +EK L  IA LL + 
Sbjct: 563 VVRIYISLLKESKTPAILEASAGAIQNLCAGRWTYGRYIRSAL-RQEKALSAIADLLTNE 621

Query: 486 NSDVVRSGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTS--NSEDILSSACYTV 543
           +  VV++ +  L N++       ++G    P + + L     N+S   SED + S   T+
Sbjct: 622 HERVVKAASGALRNLAVDARNKELIGKHAIPNLVKNLPGGQQNSSWNFSEDTVISILNTI 681

Query: 544 RNLMASQPQLAKQYFSSSMLNNIINLCRS-SASPKAAEAARLLLSDMWSSKELQGVLRQQ 602
             ++A   + AK+   +  +  ++ + +S + S K   AA L+L  +W  KEL+  L ++
Sbjct: 682 NEVIAENLEAAKKLRETQGIEKLVLINKSGNRSEKEVRAAALVLQTIWGYKELRKPLEKE 741

Query: 603 GFDRN 607
           G+ ++
Sbjct: 742 GWKKS 746


>gi|146231970 catenin, delta 1 isoform 3ABC [Homo sapiens]
          Length = 867

 Score =  228 bits (581), Expect = 1e-59
 Identities = 156/485 (32%), Positives = 252/485 (51%), Gaps = 28/485 (5%)

Query: 146 IPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQA 205
           +P+ +  L  + +  ++  A Y+QH C++++  K  V +L GI  LV LL  P + V   
Sbjct: 267 LPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLG 326

Query: 206 AAGALRNLVF-RSTTNKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKE 264
           A GAL+N+ F R   NK+  +  +G+   V LLR+  + ++ + +TG LWNLSS D +K 
Sbjct: 327 ACGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSHDSIKM 386

Query: 265 ELIADALPVLADRVIIPFSGW-CDGNSNMS-REVVDPEVFFNATGCLRNLSS-ADAGRQT 321
           E++  AL  L D VIIP SGW  + N +   R +    V  N  GCLRN+SS     R+ 
Sbjct: 387 EIVDHALHALTDEVIIPHSGWEREPNEDCKPRHIEWESVLTNTAGCLRNVSSERSEARRK 446

Query: 322 MRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLSYRLDAEVP--TRYRQLEYNA 379
           +R   GL+D+L+  VQ  +     D K VENC+C+L NLSY++  E+P   RY++   N 
Sbjct: 447 LRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLRNLSYQVHREIPQAERYQEAAPNV 506

Query: 380 RNAYTEKSSTGCFSNKSDK-------------MMNNNYDCPLPEEETNP-KGSGWLYHSD 425
            N  T   +  CF  K  K               N+  D P   + T+P +G   L+  +
Sbjct: 507 AN-NTGPHAASCFGAKKGKDEWFSRGKKPIEDPANDTVDFP---KRTSPARGYELLFQPE 562

Query: 426 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSG 485
            +R Y++L+ +SK  A LEA AGA+QNL A +      +   +  +EK L  IA LL + 
Sbjct: 563 VVRIYISLLKESKTPAILEASAGAIQNLCAGRWTYGRYIRSAL-RQEKALSAIADLLTNE 621

Query: 486 NSDVVRSGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTS--NSEDILSSACYTV 543
           +  VV++ +  L N++       ++G    P + + L     N+S   SED + S   T+
Sbjct: 622 HERVVKAASGALRNLAVDARNKELIGKHAIPNLVKNLPGGQQNSSWNFSEDTVISILNTI 681

Query: 544 RNLMASQPQLAKQYFSSSMLNNIINLCRS-SASPKAAEAARLLLSDMWSSKELQGVLRQQ 602
             ++A   + AK+   +  +  ++ + +S + S K   AA L+L  +W  KEL+  L ++
Sbjct: 682 NEVIAENLEAAKKLRETQGIEKLVLINKSGNRSEKEVRAAALVLQTIWGYKELRKPLEKE 741

Query: 603 GFDRN 607
           G+ ++
Sbjct: 742 GWKKS 746


>gi|146231940 catenin, delta 1 isoform 1ABC [Homo sapiens]
          Length = 968

 Score =  228 bits (581), Expect = 1e-59
 Identities = 156/485 (32%), Positives = 252/485 (51%), Gaps = 28/485 (5%)

Query: 146 IPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQA 205
           +P+ +  L  + +  ++  A Y+QH C++++  K  V +L GI  LV LL  P + V   
Sbjct: 368 LPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLG 427

Query: 206 AAGALRNLVF-RSTTNKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKE 264
           A GAL+N+ F R   NK+  +  +G+   V LLR+  + ++ + +TG LWNLSS D +K 
Sbjct: 428 ACGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSHDSIKM 487

Query: 265 ELIADALPVLADRVIIPFSGW-CDGNSNMS-REVVDPEVFFNATGCLRNLSS-ADAGRQT 321
           E++  AL  L D VIIP SGW  + N +   R +    V  N  GCLRN+SS     R+ 
Sbjct: 488 EIVDHALHALTDEVIIPHSGWEREPNEDCKPRHIEWESVLTNTAGCLRNVSSERSEARRK 547

Query: 322 MRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLSYRLDAEVP--TRYRQLEYNA 379
           +R   GL+D+L+  VQ  +     D K VENC+C+L NLSY++  E+P   RY++   N 
Sbjct: 548 LRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLRNLSYQVHREIPQAERYQEAAPNV 607

Query: 380 RNAYTEKSSTGCFSNKSDK-------------MMNNNYDCPLPEEETNP-KGSGWLYHSD 425
            N  T   +  CF  K  K               N+  D P   + T+P +G   L+  +
Sbjct: 608 AN-NTGPHAASCFGAKKGKDEWFSRGKKPIEDPANDTVDFP---KRTSPARGYELLFQPE 663

Query: 426 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSG 485
            +R Y++L+ +SK  A LEA AGA+QNL A +      +   +  +EK L  IA LL + 
Sbjct: 664 VVRIYISLLKESKTPAILEASAGAIQNLCAGRWTYGRYIRSAL-RQEKALSAIADLLTNE 722

Query: 486 NSDVVRSGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTS--NSEDILSSACYTV 543
           +  VV++ +  L N++       ++G    P + + L     N+S   SED + S   T+
Sbjct: 723 HERVVKAASGALRNLAVDARNKELIGKHAIPNLVKNLPGGQQNSSWNFSEDTVISILNTI 782

Query: 544 RNLMASQPQLAKQYFSSSMLNNIINLCRS-SASPKAAEAARLLLSDMWSSKELQGVLRQQ 602
             ++A   + AK+   +  +  ++ + +S + S K   AA L+L  +W  KEL+  L ++
Sbjct: 783 NEVIAENLEAAKKLRETQGIEKLVLINKSGNRSEKEVRAAALVLQTIWGYKELRKPLEKE 842

Query: 603 GFDRN 607
           G+ ++
Sbjct: 843 GWKKS 847


>gi|4504811 junction plakoglobin [Homo sapiens]
          Length = 745

 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 97/471 (20%), Positives = 176/471 (37%), Gaps = 62/471 (13%)

Query: 168 IQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLETRRQ 227
           I H           +++ GGI  LV +L SP ++V   A   L NL+      K+  R  
Sbjct: 208 ILHNLSHHREGLLAIFKSGGIPALVRMLSSPVESVLFYAITTLHNLLLYQEGAKMAVRLA 267

Query: 228 NGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKEELIADALPVLADRVIIPFSGWCD 287
           +G+++ V LL +  N +     T  L  L+  ++               ++II  +G   
Sbjct: 268 DGLQKMVPLLNK-NNPKFLAITTDCLQLLAYGNQ-------------ESKLIILANGGPQ 313

Query: 288 GNSNMSREVVDPEVFFNATGCLRNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDD 347
               + R     ++ +  +  L+ LS   + +  +    G    + A  ++  + S    
Sbjct: 314 ALVQIMRNYSYEKLLWTTSRVLKVLSVCPSNKPAIVEAGG----MQALGKHLTSNS---P 366

Query: 348 KSVENCMCVLHNLS------YRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMN 401
           + V+NC+  L NLS        L++ +     QL  +  N  T   +TG  SN +    N
Sbjct: 367 RLVQNCLWTLRNLSDVATKQEGLESVLKILVNQLSVDDVNVLT--CATGTLSNLT---CN 421

Query: 402 NNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMS 461
           N+ +  L    T   G   L H+        ++    KD   E    AL++LT+      
Sbjct: 422 NSKNKTL---VTQNSGVEALIHA--------ILRAGDKDDITEPAVCALRHLTSRH--PE 468

Query: 462 SGMSQLIGLKEKGLPQIARLLQSGNS-DVVRSGASLLSNMSRHPLLHRVMGN-QVFPEVT 519
           + M+Q       G+P I +LL   N   +V++   L+ N++  P  H  +    V P + 
Sbjct: 469 AEMAQNSVRLNYGIPAIVKLLNQPNQWPLVKATIGLIRNLALCPANHAPLQEAAVIPRLV 528

Query: 520 RLL--------------TSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNN 565
           +LL              T          + +   C    +++A  P    + F  + +  
Sbjct: 529 QLLVKAHQDAQRHVAAGTQQPYTDGVRMEEIVEGCTGALHILARDPMNRMEIFRLNTIPL 588

Query: 566 IINLCRSSASPKAAEAARLLLSDMWSSKELQGVLRQQGFDRNMLGTLAGAN 616
            + L  SS        A  +L ++   KE    +  +G    ++  L   N
Sbjct: 589 FVQLLYSSVE-NIQRVAAGVLCELAQDKEAADAIDAEGASAPLMELLHSRN 638



 Score = 40.4 bits (93), Expect = 0.005
 Identities = 86/415 (20%), Positives = 148/415 (35%), Gaps = 87/415 (20%)

Query: 146 IPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQA 205
           IP  V+ LSS  E         + +     E AK  V    G+ K+V LL   N      
Sbjct: 228 IPALVRMLSSPVESVLFYAITTLHNLLLYQEGAKMAVRLADGLQKMVPLLNKNNPKFLAI 287

Query: 206 AAGALRNLVFRSTTNKLETRRQNGIREAVSLLRRT------------------------- 240
               L+ L + +  +KL      G +  V ++R                           
Sbjct: 288 TTDCLQLLAYGNQESKLIILANGGPQALVQIMRNYSYEKLLWTTSRVLKVLSVCPSNKPA 347

Query: 241 -----GNAEIQKQLTG--------LLWNLSSTDEL--KEELIADALPVLADRVIIPFSGW 285
                G   + K LT          LW L +  ++  K+E +   L +L +++       
Sbjct: 348 IVEAGGMQALGKHLTSNSPRLVQNCLWTLRNLSDVATKQEGLESVLKILVNQL------- 400

Query: 286 CDGNSNMSREVVDPEVFFNATGCLRNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRC 345
                     V D  V   ATG L NL+  ++  +T+   +  +++L+    + +  +  
Sbjct: 401 ---------SVDDVNVLTCATGTLSNLTCNNSKNKTLVTQNSGVEALI----HAILRAGD 447

Query: 346 DDKSVENCMCVLHNLSYR-LDAEVPTRYRQLEY---------NARNAY-TEKSSTGCFSN 394
            D   E  +C L +L+ R  +AE+     +L Y         N  N +   K++ G   N
Sbjct: 448 KDDITEPAVCALRHLTSRHPEAEMAQNSVRLNYGIPAIVKLLNQPNQWPLVKATIGLIRN 507

Query: 395 KSDKMMNNNYDCPLPEEETNPKGSGWLY--HSDAIR-----TYLNLMGKSKKDATLEACA 447
            +    N+    PL E    P+    L   H DA R     T        + +  +E C 
Sbjct: 508 LALCPANH---APLQEAAVIPRLVQLLVKAHQDAQRHVAAGTQQPYTDGVRMEEIVEGCT 564

Query: 448 GALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSR 502
           GAL  L          M+++   +   +P   +LL S   ++ R  A +L  +++
Sbjct: 565 GALHILARDP------MNRMEIFRLNTIPLFVQLLYSSVENIQRVAAGVLCELAQ 613


>gi|12056468 junction plakoglobin [Homo sapiens]
          Length = 745

 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 97/471 (20%), Positives = 176/471 (37%), Gaps = 62/471 (13%)

Query: 168 IQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLETRRQ 227
           I H           +++ GGI  LV +L SP ++V   A   L NL+      K+  R  
Sbjct: 208 ILHNLSHHREGLLAIFKSGGIPALVRMLSSPVESVLFYAITTLHNLLLYQEGAKMAVRLA 267

Query: 228 NGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKEELIADALPVLADRVIIPFSGWCD 287
           +G+++ V LL +  N +     T  L  L+  ++               ++II  +G   
Sbjct: 268 DGLQKMVPLLNK-NNPKFLAITTDCLQLLAYGNQ-------------ESKLIILANGGPQ 313

Query: 288 GNSNMSREVVDPEVFFNATGCLRNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDD 347
               + R     ++ +  +  L+ LS   + +  +    G    + A  ++  + S    
Sbjct: 314 ALVQIMRNYSYEKLLWTTSRVLKVLSVCPSNKPAIVEAGG----MQALGKHLTSNS---P 366

Query: 348 KSVENCMCVLHNLS------YRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMN 401
           + V+NC+  L NLS        L++ +     QL  +  N  T   +TG  SN +    N
Sbjct: 367 RLVQNCLWTLRNLSDVATKQEGLESVLKILVNQLSVDDVNVLT--CATGTLSNLT---CN 421

Query: 402 NNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMS 461
           N+ +  L    T   G   L H+        ++    KD   E    AL++LT+      
Sbjct: 422 NSKNKTL---VTQNSGVEALIHA--------ILRAGDKDDITEPAVCALRHLTSRH--PE 468

Query: 462 SGMSQLIGLKEKGLPQIARLLQSGNS-DVVRSGASLLSNMSRHPLLHRVMGN-QVFPEVT 519
           + M+Q       G+P I +LL   N   +V++   L+ N++  P  H  +    V P + 
Sbjct: 469 AEMAQNSVRLNYGIPAIVKLLNQPNQWPLVKATIGLIRNLALCPANHAPLQEAAVIPRLV 528

Query: 520 RLL--------------TSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNN 565
           +LL              T          + +   C    +++A  P    + F  + +  
Sbjct: 529 QLLVKAHQDAQRHVAAGTQQPYTDGVRMEEIVEGCTGALHILARDPMNRMEIFRLNTIPL 588

Query: 566 IINLCRSSASPKAAEAARLLLSDMWSSKELQGVLRQQGFDRNMLGTLAGAN 616
            + L  SS        A  +L ++   KE    +  +G    ++  L   N
Sbjct: 589 FVQLLYSSVE-NIQRVAAGVLCELAQDKEAADAIDAEGASAPLMELLHSRN 638



 Score = 40.4 bits (93), Expect = 0.005
 Identities = 86/415 (20%), Positives = 148/415 (35%), Gaps = 87/415 (20%)

Query: 146 IPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQA 205
           IP  V+ LSS  E         + +     E AK  V    G+ K+V LL   N      
Sbjct: 228 IPALVRMLSSPVESVLFYAITTLHNLLLYQEGAKMAVRLADGLQKMVPLLNKNNPKFLAI 287

Query: 206 AAGALRNLVFRSTTNKLETRRQNGIREAVSLLRRT------------------------- 240
               L+ L + +  +KL      G +  V ++R                           
Sbjct: 288 TTDCLQLLAYGNQESKLIILANGGPQALVQIMRNYSYEKLLWTTSRVLKVLSVCPSNKPA 347

Query: 241 -----GNAEIQKQLTG--------LLWNLSSTDEL--KEELIADALPVLADRVIIPFSGW 285
                G   + K LT          LW L +  ++  K+E +   L +L +++       
Sbjct: 348 IVEAGGMQALGKHLTSNSPRLVQNCLWTLRNLSDVATKQEGLESVLKILVNQL------- 400

Query: 286 CDGNSNMSREVVDPEVFFNATGCLRNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRC 345
                     V D  V   ATG L NL+  ++  +T+   +  +++L+    + +  +  
Sbjct: 401 ---------SVDDVNVLTCATGTLSNLTCNNSKNKTLVTQNSGVEALI----HAILRAGD 447

Query: 346 DDKSVENCMCVLHNLSYR-LDAEVPTRYRQLEY---------NARNAY-TEKSSTGCFSN 394
            D   E  +C L +L+ R  +AE+     +L Y         N  N +   K++ G   N
Sbjct: 448 KDDITEPAVCALRHLTSRHPEAEMAQNSVRLNYGIPAIVKLLNQPNQWPLVKATIGLIRN 507

Query: 395 KSDKMMNNNYDCPLPEEETNPKGSGWLY--HSDAIR-----TYLNLMGKSKKDATLEACA 447
            +    N+    PL E    P+    L   H DA R     T        + +  +E C 
Sbjct: 508 LALCPANH---APLQEAAVIPRLVQLLVKAHQDAQRHVAAGTQQPYTDGVRMEEIVEGCT 564

Query: 448 GALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSR 502
           GAL  L          M+++   +   +P   +LL S   ++ R  A +L  +++
Sbjct: 565 GALHILARDP------MNRMEIFRLNTIPLFVQLLYSSVENIQRVAAGVLCELAQ 613


>gi|189011568 adenomatous polyposis coli [Homo sapiens]
          Length = 2843

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 60/243 (24%), Positives = 98/243 (40%), Gaps = 27/243 (11%)

Query: 126 GHSRASSKICSEDIECSGLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQL 185
           G  +A +++   D E  GLT      + S    +Y  +    + +  F D + K  +  +
Sbjct: 470 GGLQAIAELLQVDCEMYGLTN----DHYSITLRRYAGMA---LTNLTFGDVANKATLCSM 522

Query: 186 GGICK-LVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLETRRQNG-IREAVSLLRRTGNA 243
            G  + LV  L+S ++++QQ  A  LRNL +R+  N  +T R+ G ++  +         
Sbjct: 523 KGCMRALVAQLKSESEDLQQVIASVLRNLSWRADVNSKKTLREVGSVKALMECALEVKKE 582

Query: 244 EIQKQLTGLLWNLSS-TDELKEELIA--DALPVLADRVIIPFSGWCDGNSNMSREVVDPE 300
              K +   LWNLS+   E K ++ A   AL  L             G      +     
Sbjct: 583 STLKSVLSALWNLSAHCTENKADICAVDGALAFLV------------GTLTYRSQTNTLA 630

Query: 301 VFFNATGCLRNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNL 360
           +  +  G LRN+SS  A  +  R      + L   +Q+  + S      V N    L NL
Sbjct: 631 IIESGGGILRNVSSLIATNEDHRQILRENNCLQTLLQHLKSHSL---TIVSNACGTLWNL 687

Query: 361 SYR 363
           S R
Sbjct: 688 SAR 690



 Score = 38.9 bits (89), Expect = 0.014
 Identities = 40/154 (25%), Positives = 72/154 (46%), Gaps = 4/154 (2%)

Query: 438 KKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLL 497
           KK++TL++   AL NL+A      + +  + G     +  +    Q+    ++ SG  +L
Sbjct: 580 KKESTLKSVLSALWNLSAHCTENKADICAVDGALAFLVGTLTYRSQTNTLAIIESGGGIL 639

Query: 498 SNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQY 557
            N+S   +       Q+  E   L T      S+S  I+S+AC T+ NL A  P+  +  
Sbjct: 640 RNVS-SLIATNEDHRQILRENNCLQTLLQHLKSHSLTIVSNACGTLWNLSARNPKDQEAL 698

Query: 558 F---SSSMLNNIINLCRSSASPKAAEAARLLLSD 588
           +   + SML N+I+      +  +A A R L+++
Sbjct: 699 WDMGAVSMLKNLIHSKHKMIAMGSAAALRNLMAN 732


>gi|189011566 adenomatous polyposis coli [Homo sapiens]
          Length = 2843

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 60/243 (24%), Positives = 98/243 (40%), Gaps = 27/243 (11%)

Query: 126 GHSRASSKICSEDIECSGLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQL 185
           G  +A +++   D E  GLT      + S    +Y  +    + +  F D + K  +  +
Sbjct: 470 GGLQAIAELLQVDCEMYGLTN----DHYSITLRRYAGMA---LTNLTFGDVANKATLCSM 522

Query: 186 GGICK-LVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLETRRQNG-IREAVSLLRRTGNA 243
            G  + LV  L+S ++++QQ  A  LRNL +R+  N  +T R+ G ++  +         
Sbjct: 523 KGCMRALVAQLKSESEDLQQVIASVLRNLSWRADVNSKKTLREVGSVKALMECALEVKKE 582

Query: 244 EIQKQLTGLLWNLSS-TDELKEELIA--DALPVLADRVIIPFSGWCDGNSNMSREVVDPE 300
              K +   LWNLS+   E K ++ A   AL  L             G      +     
Sbjct: 583 STLKSVLSALWNLSAHCTENKADICAVDGALAFLV------------GTLTYRSQTNTLA 630

Query: 301 VFFNATGCLRNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNL 360
           +  +  G LRN+SS  A  +  R      + L   +Q+  + S      V N    L NL
Sbjct: 631 IIESGGGILRNVSSLIATNEDHRQILRENNCLQTLLQHLKSHSL---TIVSNACGTLWNL 687

Query: 361 SYR 363
           S R
Sbjct: 688 SAR 690



 Score = 38.9 bits (89), Expect = 0.014
 Identities = 40/154 (25%), Positives = 72/154 (46%), Gaps = 4/154 (2%)

Query: 438 KKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLL 497
           KK++TL++   AL NL+A      + +  + G     +  +    Q+    ++ SG  +L
Sbjct: 580 KKESTLKSVLSALWNLSAHCTENKADICAVDGALAFLVGTLTYRSQTNTLAIIESGGGIL 639

Query: 498 SNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQY 557
            N+S   +       Q+  E   L T      S+S  I+S+AC T+ NL A  P+  +  
Sbjct: 640 RNVS-SLIATNEDHRQILRENNCLQTLLQHLKSHSLTIVSNACGTLWNLSARNPKDQEAL 698

Query: 558 F---SSSMLNNIINLCRSSASPKAAEAARLLLSD 588
           +   + SML N+I+      +  +A A R L+++
Sbjct: 699 WDMGAVSMLKNLIHSKHKMIAMGSAAALRNLMAN 732


>gi|53759122 adenomatous polyposis coli [Homo sapiens]
          Length = 2843

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 60/243 (24%), Positives = 98/243 (40%), Gaps = 27/243 (11%)

Query: 126 GHSRASSKICSEDIECSGLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQL 185
           G  +A +++   D E  GLT      + S    +Y  +    + +  F D + K  +  +
Sbjct: 470 GGLQAIAELLQVDCEMYGLTN----DHYSITLRRYAGMA---LTNLTFGDVANKATLCSM 522

Query: 186 GGICK-LVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLETRRQNG-IREAVSLLRRTGNA 243
            G  + LV  L+S ++++QQ  A  LRNL +R+  N  +T R+ G ++  +         
Sbjct: 523 KGCMRALVAQLKSESEDLQQVIASVLRNLSWRADVNSKKTLREVGSVKALMECALEVKKE 582

Query: 244 EIQKQLTGLLWNLSS-TDELKEELIA--DALPVLADRVIIPFSGWCDGNSNMSREVVDPE 300
              K +   LWNLS+   E K ++ A   AL  L             G      +     
Sbjct: 583 STLKSVLSALWNLSAHCTENKADICAVDGALAFLV------------GTLTYRSQTNTLA 630

Query: 301 VFFNATGCLRNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNL 360
           +  +  G LRN+SS  A  +  R      + L   +Q+  + S      V N    L NL
Sbjct: 631 IIESGGGILRNVSSLIATNEDHRQILRENNCLQTLLQHLKSHSL---TIVSNACGTLWNL 687

Query: 361 SYR 363
           S R
Sbjct: 688 SAR 690



 Score = 38.9 bits (89), Expect = 0.014
 Identities = 40/154 (25%), Positives = 72/154 (46%), Gaps = 4/154 (2%)

Query: 438 KKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLL 497
           KK++TL++   AL NL+A      + +  + G     +  +    Q+    ++ SG  +L
Sbjct: 580 KKESTLKSVLSALWNLSAHCTENKADICAVDGALAFLVGTLTYRSQTNTLAIIESGGGIL 639

Query: 498 SNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQY 557
            N+S   +       Q+  E   L T      S+S  I+S+AC T+ NL A  P+  +  
Sbjct: 640 RNVS-SLIATNEDHRQILRENNCLQTLLQHLKSHSLTIVSNACGTLWNLSARNPKDQEAL 698

Query: 558 F---SSSMLNNIINLCRSSASPKAAEAARLLLSD 588
           +   + SML N+I+      +  +A A R L+++
Sbjct: 699 WDMGAVSMLKNLIHSKHKMIAMGSAAALRNLMAN 732


>gi|189409124 armadillo repeat containing 3 [Homo sapiens]
          Length = 872

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 31/114 (27%), Positives = 55/114 (48%), Gaps = 3/114 (2%)

Query: 150 VQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGA 209
           V  L S+++  +   +  I   C  + S  +  +   GI +L+ LL+S N+ V++AAA A
Sbjct: 322 VALLGSENDGTKIAASQAISAMC--ENSGSKDFFNNQGIPQLIQLLKSDNEEVREAAALA 379

Query: 210 LRNLVFRSTTNKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELK 263
           L NL   +  N       +GI   ++LL    +  I    T +L N++  + L+
Sbjct: 380 LANLTTCNPANANAAAEADGIDPLINLLSSKRDGAIANAAT-VLTNMAMQEPLR 432



 Score = 37.0 bits (84), Expect = 0.055
 Identities = 42/182 (23%), Positives = 79/182 (43%), Gaps = 21/182 (11%)

Query: 421 LYHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIAR 480
           L+H   +   L  +  S+ D T  A + A+  +  + G      +Q       G+PQ+ +
Sbjct: 311 LFHEQEVEKCLVALLGSENDGTKIAASQAISAMCENSGSKDFFNNQ-------GIPQLIQ 363

Query: 481 LLQSGNSDVVRSGASLLSNMSR-HPLLHRVM--GNQVFPEVTRLLTSHTGNTSNSEDILS 537
           LL+S N +V  + A  L+N++  +P         + + P +  L +   G  +N+  +L+
Sbjct: 364 LLKSDNEEVREAAALALANLTTCNPANANAAAEADGIDPLINLLSSKRDGAIANAATVLT 423

Query: 538 SACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSS---ASPKAAEAARLLLSDMWSSKE 594
           +        MA Q  L     +  +++ II+  RS+      KAA A      D+ +  E
Sbjct: 424 N--------MAMQEPLRLNIQNHDIMHAIISPLRSANTVVQSKAALAVTATACDVEARTE 475

Query: 595 LQ 596
           L+
Sbjct: 476 LR 477


>gi|148227672 catenin (cadherin-associated protein), beta 1, 88kDa
           [Homo sapiens]
          Length = 781

 Score = 40.8 bits (94), Expect = 0.004
 Identities = 77/350 (22%), Positives = 142/350 (40%), Gaps = 49/350 (14%)

Query: 182 VYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLETRRQNGIREAVSLLRRTG 241
           +++ GGI  LV +L SP  +V   A   L NL+      K+  R   G+++ V+LL +T 
Sbjct: 231 IFKSGGIPALVKMLGSPVDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKT- 289

Query: 242 NAEIQKQLTGLLWNLSSTDELKEELIADALPVLADRVIIPFSGWCDGNSNMSREVVDPEV 301
           N +     T  L  L+  ++               ++II  SG      N+ R     ++
Sbjct: 290 NVKFLAITTDCLQILAYGNQ-------------ESKLIILASGGPQALVNIMRTYTYEKL 336

Query: 302 FFNATGCLRNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLS 361
            +  +  L+ LS   + +  +    G+  +L  ++ +         + V+NC+  L NLS
Sbjct: 337 LWTTSRVLKVLSVCSSNKPAIVEAGGM-QALGLHLTD------PSQRLVQNCLWTLRNLS 389

Query: 362 ------YRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKS-DKMMNNNYDCPLPEEETN 414
                   ++  + T  + L  +  N  T   + G  SN + +   N    C +   E  
Sbjct: 390 DAATKQEGMEGLLGTLVQLLGSDDINVVT--CAAGILSNLTCNNYKNKMMVCQVGGIEA- 446

Query: 415 PKGSGWLYHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKG 474
                       +RT L      ++D T E    AL++LT+      + M+Q       G
Sbjct: 447 -----------LVRTVLR--AGDREDIT-EPAICALRHLTSRH--QEAEMAQNAVRLHYG 490

Query: 475 LPQIARLLQ-SGNSDVVRSGASLLSNMSRHPLLHRVMGNQ-VFPEVTRLL 522
           LP + +LL    +  ++++   L+ N++  P  H  +  Q   P + +LL
Sbjct: 491 LPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLL 540



 Score = 35.4 bits (80), Expect = 0.16
 Identities = 24/69 (34%), Positives = 34/69 (49%)

Query: 176 ESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLETRRQNGIREAVS 235
           ++A +Q    G +  LV LL S + NV   AAG L NL   +  NK+   +  GI   V 
Sbjct: 390 DAATKQEGMEGLLGTLVQLLGSDDINVVTCAAGILSNLTCNNYKNKMMVCQVGGIEALVR 449

Query: 236 LLRRTGNAE 244
            + R G+ E
Sbjct: 450 TVLRAGDRE 458



 Score = 35.0 bits (79), Expect = 0.21
 Identities = 48/219 (21%), Positives = 79/219 (36%), Gaps = 30/219 (13%)

Query: 146 IPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQA 205
           IP  V+ L S  +         + +     E AK  V   GG+ K+V LL   N      
Sbjct: 237 IPALVKMLGSPVDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKTNVKFLAI 296

Query: 206 AAGALRNLVFRSTTNKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKEE 265
               L+ L + +  +KL      G +  V+++R     +       LLW  S   ++   
Sbjct: 297 TTDCLQILAYGNQESKLIILASGGPQALVNIMRTYTYEK-------LLWTTSRVLKVL-S 348

Query: 266 LIADALPVLADRVIIPFSGWCDGNSNMSREVVDP--EVFFNATGCLRNLSSADAGRQTMR 323
           + +   P + +           G   +   + DP   +  N    LRNLS A   ++ M 
Sbjct: 349 VCSSNKPAIVE---------AGGMQALGLHLTDPSQRLVQNCLWTLRNLSDAATKQEGME 399

Query: 324 NYSGLIDSLMAYVQNCVAASRCDDKSVENCMC-VLHNLS 361
              G +  L+            DD +V  C   +L NL+
Sbjct: 400 GLLGTLVQLLG----------SDDINVVTCAAGILSNLT 428


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.129    0.380 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,715,118
Number of Sequences: 37866
Number of extensions: 976420
Number of successful extensions: 2573
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 37
Number of HSP's successfully gapped in prelim test: 20
Number of HSP's that attempted gapping in prelim test: 2340
Number of HSP's gapped (non-prelim): 123
length of query: 625
length of database: 18,247,518
effective HSP length: 108
effective length of query: 517
effective length of database: 14,157,990
effective search space: 7319680830
effective search space used: 7319680830
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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