Guide to the Human Genome
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Search of human proteins with 11128025

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|11128025 protocadherin gamma subfamily C, 4 isoform 1
precursor [Homo sapiens]
         (938 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|11128025 protocadherin gamma subfamily C, 4 isoform 1 precurs...  1878   0.0  
gi|14277682 protocadherin gamma subfamily C, 4 isoform 2 precurs...  1626   0.0  
gi|11128023 protocadherin gamma subfamily C, 5 isoform 1 precurs...   926   0.0  
gi|11128039 protocadherin gamma subfamily A, 11 isoform 1 precur...   832   0.0  
gi|11056026 protocadherin gamma subfamily A, 4 isoform 1 precurs...   830   0.0  
gi|14277675 protocadherin gamma subfamily C, 3 isoform 1 precurs...   828   0.0  
gi|11128031 protocadherin gamma subfamily B, 5 isoform 1 precurs...   825   0.0  
gi|11128037 protocadherin gamma subfamily B, 1 isoform 1 precurs...   819   0.0  
gi|11056024 protocadherin gamma subfamily A, 5 isoform 1 precurs...   816   0.0  
gi|11056065 protocadherin gamma subfamily A, 6 isoform 1 precurs...   813   0.0  
gi|14589880 protocadherin gamma subfamily A, 3 isoform 1 precurs...   811   0.0  
gi|11056032 protocadherin gamma subfamily A, 1 isoform 1 precurs...   805   0.0  
gi|13470082 protocadherin gamma subfamily B, 4 isoform 1 precurs...   805   0.0  
gi|11128041 protocadherin gamma subfamily A, 10 isoform 1 precur...   805   0.0  
gi|11128027 protocadherin gamma subfamily B, 7 isoform 1 precurs...   805   0.0  
gi|8850232 protocadherin gamma subfamily A, 12 isoform 1 precurs...   803   0.0  
gi|11128035 protocadherin gamma subfamily B, 2 isoform 1 precurs...   803   0.0  
gi|11128029 protocadherin gamma subfamily B, 6 isoform 1 precurs...   801   0.0  
gi|11056030 protocadherin gamma subfamily A, 2 isoform 1 precurs...   801   0.0  
gi|14270484 protocadherin gamma subfamily A, 8 isoform 1 precurs...   796   0.0  
gi|11128043 protocadherin gamma subfamily A, 9 isoform 1 precurs...   795   0.0  
gi|11056063 protocadherin gamma subfamily A, 7 isoform 1 precurs...   793   0.0  
gi|11128033 protocadherin gamma subfamily B, 3 isoform 1 precurs...   786   0.0  
gi|14277685 protocadherin gamma subfamily C, 5 isoform 2 precurs...   678   0.0  
gi|9256600 protocadherin alpha subfamily C, 2 isoform 1 precurso...   627   e-179
gi|14165431 protocadherin alpha subfamily C, 2 isoform 2 precurs...   607   e-173
gi|9256596 protocadherin alpha 8 isoform 1 precursor [Homo sapiens]   600   e-171
gi|14196451 protocadherin gamma subfamily A, 11 isoform 2 precur...   592   e-169
gi|14717401 protocadherin alpha subfamily C, 1 isoform 1 precurs...   590   e-168
gi|14277677 protocadherin gamma subfamily C, 3 isoform 2 precurs...   588   e-167

>gi|11128025 protocadherin gamma subfamily C, 4 isoform 1 precursor
           [Homo sapiens]
          Length = 938

 Score = 1878 bits (4866), Expect = 0.0
 Identities = 938/938 (100%), Positives = 938/938 (100%)

Query: 1   MLRKVRSWTEIWRWATLLFLFYHLGYVCGQIRYPVPEESQEGTFVGNVAQDFLLDTDSLS 60
           MLRKVRSWTEIWRWATLLFLFYHLGYVCGQIRYPVPEESQEGTFVGNVAQDFLLDTDSLS
Sbjct: 1   MLRKVRSWTEIWRWATLLFLFYHLGYVCGQIRYPVPEESQEGTFVGNVAQDFLLDTDSLS 60

Query: 61  ARRLQVAGEVNQRHFRVDLDSGALLIKNPIDREALCGLSASCIVPLEFVTEGPLEMYRAE 120
           ARRLQVAGEVNQRHFRVDLDSGALLIKNPIDREALCGLSASCIVPLEFVTEGPLEMYRAE
Sbjct: 61  ARRLQVAGEVNQRHFRVDLDSGALLIKNPIDREALCGLSASCIVPLEFVTEGPLEMYRAE 120

Query: 121 VEIVDVNDHAPRFPRQQLDLEIGEAAPPGQRFPLEKAQDADVGSNSISSYRLSSNEHFAL 180
           VEIVDVNDHAPRFPRQQLDLEIGEAAPPGQRFPLEKAQDADVGSNSISSYRLSSNEHFAL
Sbjct: 121 VEIVDVNDHAPRFPRQQLDLEIGEAAPPGQRFPLEKAQDADVGSNSISSYRLSSNEHFAL 180

Query: 181 DVKKRSDGSLVPELLLEKPLDREKQSDYRLVLTAVDGGNPPRSGTAELRVSVLDVNDNAP 240
           DVKKRSDGSLVPELLLEKPLDREKQSDYRLVLTAVDGGNPPRSGTAELRVSVLDVNDNAP
Sbjct: 181 DVKKRSDGSLVPELLLEKPLDREKQSDYRLVLTAVDGGNPPRSGTAELRVSVLDVNDNAP 240

Query: 241 AFQQSSYRISVLESAPAGMVLIQLNASDPDLGPSGNVTFYFSGHTPDRVRNLFSLHPTTG 300
           AFQQSSYRISVLESAPAGMVLIQLNASDPDLGPSGNVTFYFSGHTPDRVRNLFSLHPTTG
Sbjct: 241 AFQQSSYRISVLESAPAGMVLIQLNASDPDLGPSGNVTFYFSGHTPDRVRNLFSLHPTTG 300

Query: 301 KLTLLGPLDFESENYYEFDVRARDGGSPAMEQHCSLRVDLLDVNDNAPYITVTSELGTLP 360
           KLTLLGPLDFESENYYEFDVRARDGGSPAMEQHCSLRVDLLDVNDNAPYITVTSELGTLP
Sbjct: 301 KLTLLGPLDFESENYYEFDVRARDGGSPAMEQHCSLRVDLLDVNDNAPYITVTSELGTLP 360

Query: 361 ESAEPGTVVALISVQDPDSGSNGDVSLRIPDHLPFALKSAFRNQFSLVTAGPLDREAKSS 420
           ESAEPGTVVALISVQDPDSGSNGDVSLRIPDHLPFALKSAFRNQFSLVTAGPLDREAKSS
Sbjct: 361 ESAEPGTVVALISVQDPDSGSNGDVSLRIPDHLPFALKSAFRNQFSLVTAGPLDREAKSS 420

Query: 421 YDIMVTASDAGNPPLSTHRTIFLNISDVNDNPPSFFQRSHEVFVPENNRPGDLLCSLAAS 480
           YDIMVTASDAGNPPLSTHRTIFLNISDVNDNPPSFFQRSHEVFVPENNRPGDLLCSLAAS
Sbjct: 421 YDIMVTASDAGNPPLSTHRTIFLNISDVNDNPPSFFQRSHEVFVPENNRPGDLLCSLAAS 480

Query: 481 DPDSGLNALISYSLLEPRNRDVSASSFISLNPQTGAVHATRSFDYEQTQTLQFEVQARDR 540
           DPDSGLNALISYSLLEPRNRDVSASSFISLNPQTGAVHATRSFDYEQTQTLQFEVQARDR
Sbjct: 481 DPDSGLNALISYSLLEPRNRDVSASSFISLNPQTGAVHATRSFDYEQTQTLQFEVQARDR 540

Query: 541 GNPPLSSTVTVRLFVLDLNDNAPAVLRPRARPGSLCPQALPPSVGAGHLITKVTAVDLDS 600
           GNPPLSSTVTVRLFVLDLNDNAPAVLRPRARPGSLCPQALPPSVGAGHLITKVTAVDLDS
Sbjct: 541 GNPPLSSTVTVRLFVLDLNDNAPAVLRPRARPGSLCPQALPPSVGAGHLITKVTAVDLDS 600

Query: 601 GYNAWVSYQLLEAPDPSLFAVSRYAGEVRTAVPIPADLPPQKLVIVVKDSGSPPLSTSVT 660
           GYNAWVSYQLLEAPDPSLFAVSRYAGEVRTAVPIPADLPPQKLVIVVKDSGSPPLSTSVT
Sbjct: 601 GYNAWVSYQLLEAPDPSLFAVSRYAGEVRTAVPIPADLPPQKLVIVVKDSGSPPLSTSVT 660

Query: 661 LLVSLEEDTHPVVPDLRESSAPREGESRLTLYLAVSLVAICFVSFGSFVALLSKCLRGAA 720
           LLVSLEEDTHPVVPDLRESSAPREGESRLTLYLAVSLVAICFVSFGSFVALLSKCLRGAA
Sbjct: 661 LLVSLEEDTHPVVPDLRESSAPREGESRLTLYLAVSLVAICFVSFGSFVALLSKCLRGAA 720

Query: 721 CGVTCFPAGTCACLTRSRRREGLPPSNGILRIQLGSDDPIKFVDVGGHSHGCTPLASAPT 780
           CGVTCFPAGTCACLTRSRRREGLPPSNGILRIQLGSDDPIKFVDVGGHSHGCTPLASAPT
Sbjct: 721 CGVTCFPAGTCACLTRSRRREGLPPSNGILRIQLGSDDPIKFVDVGGHSHGCTPLASAPT 780

Query: 781 RSDSFMMVKSPSAPMAGEPVRPSCPPSDLLYGLEQAPPNTDWRFSQAQRPGTSGSQNGDD 840
           RSDSFMMVKSPSAPMAGEPVRPSCPPSDLLYGLEQAPPNTDWRFSQAQRPGTSGSQNGDD
Sbjct: 781 RSDSFMMVKSPSAPMAGEPVRPSCPPSDLLYGLEQAPPNTDWRFSQAQRPGTSGSQNGDD 840

Query: 841 TGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQN 900
           TGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQN
Sbjct: 841 TGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQN 900

Query: 901 VYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK 938
           VYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK
Sbjct: 901 VYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK 938


>gi|14277682 protocadherin gamma subfamily C, 4 isoform 2 precursor
           [Homo sapiens]
          Length = 871

 Score = 1626 bits (4211), Expect = 0.0
 Identities = 817/831 (98%), Positives = 817/831 (98%)

Query: 1   MLRKVRSWTEIWRWATLLFLFYHLGYVCGQIRYPVPEESQEGTFVGNVAQDFLLDTDSLS 60
           MLRKVRSWTEIWRWATLLFLFYHLGYVCGQIRYPVPEESQEGTFVGNVAQDFLLDTDSLS
Sbjct: 1   MLRKVRSWTEIWRWATLLFLFYHLGYVCGQIRYPVPEESQEGTFVGNVAQDFLLDTDSLS 60

Query: 61  ARRLQVAGEVNQRHFRVDLDSGALLIKNPIDREALCGLSASCIVPLEFVTEGPLEMYRAE 120
           ARRLQVAGEVNQRHFRVDLDSGALLIKNPIDREALCGLSASCIVPLEFVTEGPLEMYRAE
Sbjct: 61  ARRLQVAGEVNQRHFRVDLDSGALLIKNPIDREALCGLSASCIVPLEFVTEGPLEMYRAE 120

Query: 121 VEIVDVNDHAPRFPRQQLDLEIGEAAPPGQRFPLEKAQDADVGSNSISSYRLSSNEHFAL 180
           VEIVDVNDHAPRFPRQQLDLEIGEAAPPGQRFPLEKAQDADVGSNSISSYRLSSNEHFAL
Sbjct: 121 VEIVDVNDHAPRFPRQQLDLEIGEAAPPGQRFPLEKAQDADVGSNSISSYRLSSNEHFAL 180

Query: 181 DVKKRSDGSLVPELLLEKPLDREKQSDYRLVLTAVDGGNPPRSGTAELRVSVLDVNDNAP 240
           DVKKRSDGSLVPELLLEKPLDREKQSDYRLVLTAVDGGNPPRSGTAELRVSVLDVNDNAP
Sbjct: 181 DVKKRSDGSLVPELLLEKPLDREKQSDYRLVLTAVDGGNPPRSGTAELRVSVLDVNDNAP 240

Query: 241 AFQQSSYRISVLESAPAGMVLIQLNASDPDLGPSGNVTFYFSGHTPDRVRNLFSLHPTTG 300
           AFQQSSYRISVLESAPAGMVLIQLNASDPDLGPSGNVTFYFSGHTPDRVRNLFSLHPTTG
Sbjct: 241 AFQQSSYRISVLESAPAGMVLIQLNASDPDLGPSGNVTFYFSGHTPDRVRNLFSLHPTTG 300

Query: 301 KLTLLGPLDFESENYYEFDVRARDGGSPAMEQHCSLRVDLLDVNDNAPYITVTSELGTLP 360
           KLTLLGPLDFESENYYEFDVRARDGGSPAMEQHCSLRVDLLDVNDNAPYITVTSELGTLP
Sbjct: 301 KLTLLGPLDFESENYYEFDVRARDGGSPAMEQHCSLRVDLLDVNDNAPYITVTSELGTLP 360

Query: 361 ESAEPGTVVALISVQDPDSGSNGDVSLRIPDHLPFALKSAFRNQFSLVTAGPLDREAKSS 420
           ESAEPGTVVALISVQDPDSGSNGDVSLRIPDHLPFALKSAFRNQFSLVTAGPLDREAKSS
Sbjct: 361 ESAEPGTVVALISVQDPDSGSNGDVSLRIPDHLPFALKSAFRNQFSLVTAGPLDREAKSS 420

Query: 421 YDIMVTASDAGNPPLSTHRTIFLNISDVNDNPPSFFQRSHEVFVPENNRPGDLLCSLAAS 480
           YDIMVTASDAGNPPLSTHRTIFLNISDVNDNPPSFFQRSHEVFVPENNRPGDLLCSLAAS
Sbjct: 421 YDIMVTASDAGNPPLSTHRTIFLNISDVNDNPPSFFQRSHEVFVPENNRPGDLLCSLAAS 480

Query: 481 DPDSGLNALISYSLLEPRNRDVSASSFISLNPQTGAVHATRSFDYEQTQTLQFEVQARDR 540
           DPDSGLNALISYSLLEPRNRDVSASSFISLNPQTGAVHATRSFDYEQTQTLQFEVQARDR
Sbjct: 481 DPDSGLNALISYSLLEPRNRDVSASSFISLNPQTGAVHATRSFDYEQTQTLQFEVQARDR 540

Query: 541 GNPPLSSTVTVRLFVLDLNDNAPAVLRPRARPGSLCPQALPPSVGAGHLITKVTAVDLDS 600
           GNPPLSSTVTVRLFVLDLNDNAPAVLRPRARPGSLCPQALPPSVGAGHLITKVTAVDLDS
Sbjct: 541 GNPPLSSTVTVRLFVLDLNDNAPAVLRPRARPGSLCPQALPPSVGAGHLITKVTAVDLDS 600

Query: 601 GYNAWVSYQLLEAPDPSLFAVSRYAGEVRTAVPIPADLPPQKLVIVVKDSGSPPLSTSVT 660
           GYNAWVSYQLLEAPDPSLFAVSRYAGEVRTAVPIPADLPPQKLVIVVKDSGSPPLSTSVT
Sbjct: 601 GYNAWVSYQLLEAPDPSLFAVSRYAGEVRTAVPIPADLPPQKLVIVVKDSGSPPLSTSVT 660

Query: 661 LLVSLEEDTHPVVPDLRESSAPREGESRLTLYLAVSLVAICFVSFGSFVALLSKCLRGAA 720
           LLVSLEEDTHPVVPDLRESSAPREGESRLTLYLAVSLVAICFVSFGSFVALLSKCLRGAA
Sbjct: 661 LLVSLEEDTHPVVPDLRESSAPREGESRLTLYLAVSLVAICFVSFGSFVALLSKCLRGAA 720

Query: 721 CGVTCFPAGTCACLTRSRRREGLPPSNGILRIQLGSDDPIKFVDVGGHSHGCTPLASAPT 780
           CGVTCFPAGTCACLTRSRRREGLPPSNGILRIQLGSDDPIKFVDVGGHSHGCTPLASAPT
Sbjct: 721 CGVTCFPAGTCACLTRSRRREGLPPSNGILRIQLGSDDPIKFVDVGGHSHGCTPLASAPT 780

Query: 781 RSDSFMMVKSPSAPMAGEPVRPSCPPSDLLYGLEQAPPNTDWRFSQAQRPG 831
           RSDSFMMVKSPSAPMAGEPVRPSCPPSDLLYGLE  P            PG
Sbjct: 781 RSDSFMMVKSPSAPMAGEPVRPSCPPSDLLYGLEVRPLQAQQMLEGYSDPG 831


>gi|11128023 protocadherin gamma subfamily C, 5 isoform 1 precursor
           [Homo sapiens]
          Length = 944

 Score =  926 bits (2392), Expect = 0.0
 Identities = 500/929 (53%), Positives = 634/929 (68%), Gaps = 24/929 (2%)

Query: 25  GYVCGQIRYPVPEESQEGTFVGNVAQDFLLDTDSLSARRLQVAGEVNQRHFRVDLDSGAL 84
           G+V GQ+RY V EES+ GT VGNVAQD  L    L +RRLQ+  E N R+F + L SGAL
Sbjct: 25  GWVSGQLRYSVVEESEPGTLVGNVAQDLGLKMTDLLSRRLQLGSEENGRYFSLSLMSGAL 84

Query: 85  LIKNPIDREALCGLSASCIVPLEFVTEGPLEMYRAEVEIVDVNDHAPRFPRQQLDLEIGE 144
            +   IDRE+LCG S SC++P++ VTE PLE+ R EVEI+D+ND++P F   + ++ I E
Sbjct: 85  AVNQKIDRESLCGASTSCLLPVQVVTEHPLELIRVEVEILDLNDNSPSFATPEREMRISE 144

Query: 145 AAPPGQRFPLEKAQDADVGSNSISSYRLSSNEHFALDVKKRSDGSLVPELLLEKPLDREK 204
           +A  G RFPL+ AQD DVG+N++S Y LS N HF+L+VK   DG   PEL+LE+ LDRE 
Sbjct: 145 SAASGARFPLDSAQDPDVGTNTVSFYTLSPNSHFSLNVKTLKDGKPFPELVLEQQLDREA 204

Query: 205 QSDYRLVLTAVDGGNPPRSGTAELRVSVLDVNDNAPAFQQSSYRISVLESAPAGMVLIQL 264
           Q+ ++LVLTAVDGG P RSGT  + V VLD+NDNAP FQ S  R+ + E+AP G +L++L
Sbjct: 205 QARHQLVLTAVDGGTPARSGTTLISVIVLDINDNAPTFQSSVLRVGIPENAPIGTLLLRL 264

Query: 265 NASDPDLGPSGNVTFYFSGHTPDRVRNLFSLHPTTGKLTLLGPLDFESENYYEFDVRARD 324
           NA+DPD G +G + + F  HT + VRNLF L P++G + +LGP+DFE   +YE   RARD
Sbjct: 265 NATDPDEGTNGQLDYSFGDHTSEAVRNLFGLDPSSGAIHVLGPIDFEESRFYEIHARARD 324

Query: 325 GGSPAMEQHCSLRVDLLDVNDNAPYITVTSELGTLPESAEPGTVVALISVQDPDSGSNGD 384
            G PAME HC ++VD+ DVNDNAP + + S    + ES   GTVV L +V+D DSG NG+
Sbjct: 325 QGQPAMEGHCVIQVDVGDVNDNAPEVLLASLANPVLESTPVGTVVGLFNVRDRDSGRNGE 384

Query: 385 VSLRIPDHLPFALKSAFRNQFSLVTAGPLDREAKSSYDIMVTASDAGNPPLSTHRTIFLN 444
           VSL I   LPF +K +  N +SL+T+ PLDREA S Y I + ASDAG+P L  H TI LN
Sbjct: 385 VSLDISPDLPFQIKPS-ENHYSLLTSQPLDREATSHYIIELLASDAGSPSLHKHLTIRLN 443

Query: 445 ISDVNDNPPSFFQRSHEVFVPENNRPGDLLCSLAASDPDSGLNALISYSLLEPRNRDVSA 504
           ISDVNDN P F Q+ +  ++ EN  PG LLC++AASDPD+G NA ++YS++  + +   A
Sbjct: 444 ISDVNDNAPRFNQQLYTAYILENRPPGSLLCTVAASDPDTGDNARLTYSIVGNQVQGAPA 503

Query: 505 SSFISLNPQTGAVHATRSFDYEQTQTLQFEVQARDRGNPPLSSTVTVRLFVLDLNDNAPA 564
           SSF+ +NP+ G + A R+FDYE  Q LQ  V  RD G+PPL +  ++ +FVLD NDNAPA
Sbjct: 504 SSFVYVNPEDGRIFAQRTFDYELLQMLQIVVGVRDSGSPPLHANTSLHVFVLDENDNAPA 563

Query: 565 VLRPRARPGSLCPQALPPSVGAGHLITKVTAVDLDSGYNAWVSYQLL-EAPDPSLFAVSR 623
           VL PR       PQ LP S   G L+TKVTAVD D+G+NAW+SY LL ++  P LF VS 
Sbjct: 564 VLHPRPDWEHSAPQRLPRSAPPGSLVTKVTAVDADAGHNAWLSYSLLPQSTAPGLFLVST 623

Query: 624 YAGEVRTA-VPIPADLPPQKLVIVVKDSGSPPLSTSVTLLVSLEEDTHPVVPDLRESSAP 682
           + GEVRTA   +  D   Q++V++V+D+G P LS++ T+L+ LE++    +P   +    
Sbjct: 624 HTGEVRTARALLEDDSDTQQVVVLVRDNGDPSLSSTATVLLVLEDEDPEEMPKSSDFLIH 683

Query: 683 REGESRLTLYLAVSLVAICFVSFGSFVALLSKCLRGAACGVTCFPAGTCACLTRSRRREG 742
               S LTLYL V+L  +  +S  +F  L +KCL+G A G      G   C    RR++ 
Sbjct: 684 PPERSDLTLYLIVALATVSLLSLVTFTFLSAKCLQGNADG----DGGGGQC---CRRQDS 736

Query: 743 LPP---SNGILRIQLGSDDPIKFVDV-----GGHSHGCTPLASAPTRSDSF-----MMVK 789
             P         +Q+ SD  +K+++V        SH      S  +    F     + V+
Sbjct: 737 PSPDFYKQSSPNLQVSSDGTLKYMEVTLRPTDSQSHCYRTCFSPASDGSDFTFLRPLSVQ 796

Query: 790 SPSAPMAGEPVRPSCPPSDLLYGLEQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQF 849
            P+A +A EP       + L    +QAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQF
Sbjct: 797 QPTA-LALEPDAIRSRSNTLRERSQQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQF 855

Query: 850 DTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNAT 909
           DTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNAT
Sbjct: 856 DTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNAT 915

Query: 910 LTNAAGKRDGKAPAGGNGNKKKSGKKEKK 938
           LTNAAGKRDGKAPAGGNGNKKKSGKKEKK
Sbjct: 916 LTNAAGKRDGKAPAGGNGNKKKSGKKEKK 944


>gi|11128039 protocadherin gamma subfamily A, 11 isoform 1 precursor
           [Homo sapiens]
          Length = 935

 Score =  832 bits (2150), Expect = 0.0
 Identities = 451/938 (48%), Positives = 615/938 (65%), Gaps = 38/938 (4%)

Query: 18  LFLFYHLGYVCGQIRYPVPEESQEGTFVGNVAQDFLLDTDSLSARRLQVAGEVNQRHFRV 77
           +FL    G+   QIRY VPEE+++G+FVGN+++D  L+   L+ R +++      + F V
Sbjct: 19  IFLGTLRGFRARQIRYSVPEETEKGSFVGNISKDLGLEPRELAKRGVRIVSRGKTQLFAV 78

Query: 78  DLDSGALLIKNPIDREALCGLSASCIVPLEFVTEGPLEMYRAEVEIVDVNDHAPRFPRQQ 137
           +  SG+L+    IDRE LC   +SC + +E + E  L++Y  EVEI+D+ND+AP F   +
Sbjct: 79  NPRSGSLITAGRIDREELCETVSSCFLNMELLVEDTLKIYGVEVEIIDINDNAPSFQEDE 138

Query: 138 LDLEIGEAAPPGQRFPLEKAQDADVGSNSISSYRLSSNEHFALDVKKRSDGSLVPELLLE 197
           +++++ E A PG RF L  A+D DVG NS+ SY+LS N +F+L ++ R+DG+  PEL+LE
Sbjct: 139 VEIKVSEHAIPGARFALPNARDPDVGVNSLQSYQLSPNNYFSLQLRGRTDGAKNPELVLE 198

Query: 198 KPLDREKQSDYRLVLTAVDGGNPPRSGTAELRVSVLDVNDNAPAFQQSSYRISVLESAPA 257
             LDREK++ + L+LTA+DGG+P R G   +RV VLDVND+ P F QS YR+SV E+  +
Sbjct: 199 GSLDREKEAAHLLLLTALDGGDPIRKGAVPIRVVVLDVNDHIPMFTQSVYRVSVPENISS 258

Query: 258 GMVLIQLNASDPDLGPSGNVTFYFSGHTPDRVRNLFSLHPTTGKLTLLGPLDFESENYYE 317
           G  ++ +NA+DPD G +G V + F  +   +   +F L   TG++ + G LDFE   +YE
Sbjct: 259 GTRVLMVNATDPDEGINGEVMYSFR-NMESKASEIFQLDSQTGEVQVRGSLDFEKYRFYE 317

Query: 318 FDVRARDGGSPAMEQHCSLRVDLLDVNDNAPYITVTSELGTLPESAEPGTVVALISVQDP 377
            +++ +DGG   +    ++ + ++DVNDNAP IT+TS + ++ E++ PGTV+AL++VQD 
Sbjct: 318 MEIQGQDGGG--LFTTTTMLITVVDVNDNAPEITITSSINSILENSPPGTVIALLNVQDQ 375

Query: 378 DSGSNGDVSLRIPDHLPFALKSAFRNQFSLVTAGPLDREAKSSYDIMVTASDAGNPPLST 437
           DSG NG VS  IP+HLPF L+  + N + L+T+  LDRE   SY+I +TA+D G+PPLS 
Sbjct: 376 DSGENGQVSCFIPNHLPFKLEKTYGNYYKLITSRVLDRELVQSYNITLTATDQGSPPLSA 435

Query: 438 HRTIFLNISDVNDNPPSFFQRSHEVFVPENNRPGDLLCSLAASDPDSGLNALISYSLLEP 497
              ++LN++D NDNPP F   S+  ++PENN  G  + S+ A DPDS  NAL++YSL + 
Sbjct: 436 ETHVWLNVADDNDNPPVFPHSSYSAYIPENNPRGASIFSVTALDPDSKQNALVTYSLTDD 495

Query: 498 RNRDVSASSFISLNPQTGAVHATRSFDYEQTQTLQFEVQARDRGNPPLSSTVTVRLFVLD 557
             + V  SS++S+N  TG ++A +SFDYEQ + L+  V ARD G+PPLSS V++ LFVLD
Sbjct: 496 TVQGVPLSSYVSINSNTGVLYALQSFDYEQFRDLELRVIARDSGDPPLSSNVSLSLFVLD 555

Query: 558 LNDNAPAVLRPR-ARPGSLCPQALPPSVGAGHLITKVTAVDLDSGYNAWVSYQLLEAPDP 616
            NDNAP +L P     GS   +  P S   G+L+TKV AVD DSG NAW+SY+LL+A +P
Sbjct: 556 QNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDKDSGQNAWLSYRLLKASEP 615

Query: 617 SLFAVSRYAGEVRTA-VPIPADLPPQKLVIVVKDSGSPPLSTSVTLLVSLEEDTHPVVPD 675
            LFAV  + GEVRTA   +  D   Q LV+ V+D G PPLS +VTL V++ +    V+ D
Sbjct: 616 GLFAVGEHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADSIPEVLAD 675

Query: 676 LRESSAPREGE-SRLTLYLAVSLVAICFVSFGSFVALL---------SKCLRGAACGVTC 725
           L    +    E S L+LYL V++ A+  +     + LL         S+ L+ +  G+  
Sbjct: 676 LGSLESLANSETSDLSLYLVVAVAAVSCIFLVFVIVLLALRLWRWHKSRLLQASEGGLAG 735

Query: 726 FPAGTCACLTRSRRREGLPPSNGILR-----IQLGSDDPIKFVDVGGHSHGCTPLASAPT 780
            P              G+      L+     + L +D     +     ++G T ++    
Sbjct: 736 MPTSHFV---------GVDGVQAFLQTYSHEVSLIADSQKSHLIFPQPNYGDTLISQESC 786

Query: 781 RSDSFMMVKSPSAPMAGEPVRPSCPPSDLLYGLEQAPPNTDWRFSQAQRPGTSGSQNGDD 840
                +++   SA + G+     C P+      +QAPPNTDWRFSQAQRPGTSGSQNGDD
Sbjct: 787 EKSEPLLIAEDSAIILGK-----CDPT----SNQQAPPNTDWRFSQAQRPGTSGSQNGDD 837

Query: 841 TGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQN 900
           TGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQN
Sbjct: 838 TGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQN 897

Query: 901 VYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK 938
           VYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK
Sbjct: 898 VYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK 935


>gi|11056026 protocadherin gamma subfamily A, 4 isoform 1 precursor
           [Homo sapiens]
          Length = 931

 Score =  830 bits (2145), Expect = 0.0
 Identities = 462/926 (49%), Positives = 598/926 (64%), Gaps = 41/926 (4%)

Query: 30  QIRYPVPEESQEGTFVGNVAQDFLLDTDSLSARRLQVAGEVNQRHFRVDLDSGALLIKNP 89
           QI Y V EE +EG+ VGN+A+D  L    L+ R +++      + F ++  SG L+    
Sbjct: 30  QILYSVFEEQEEGSVVGNIAKDLGLAPRELAERGVRIVSRGRTQLFALNPRSGTLVTAGR 89

Query: 90  IDREALCGLSASCIVPLEFVTEGPLEMYRAEVEIVDVNDHAPRFPRQQLDLEIGEAAPPG 149
           IDRE LC  S +C+  LE + E  +++ R EVEI+DVND+ P F  +Q ++++ E   PG
Sbjct: 90  IDREELCDRSPNCVTNLEILLEDTVKILRVEVEIIDVNDNPPSFGTEQREIKVAENENPG 149

Query: 150 QRFPLEKAQDADVGSNSISSYRLSSNEHFALDVKKRSDGSLVPELLLEKPLDREKQSDYR 209
            RFPL +A D DVG NS+  Y+L+SN +F+LDV+  +DG   PEL+LE+ LDRE+++ + 
Sbjct: 150 ARFPLPEAFDPDVGVNSLQGYQLNSNGYFSLDVQSGADGIKYPELVLERALDREEEAVHH 209

Query: 210 LVLTAVDGGNPPRSGTAELRVSVLDVNDNAPAFQQSSYRISVLESAPAGMVLIQLNASDP 269
           LVLTA DGG+P RSGTA + + ++D NDNAP F Q  Y +SV E+ P G  L+ + A+DP
Sbjct: 210 LVLTAFDGGDPVRSGTARILIILVDTNDNAPVFTQPEYHVSVRENVPVGTRLLTVKATDP 269

Query: 270 DLGPSGNVTFYFSGHTPDRVRNLFSLHPTTGKLTLLGPLDFESENYYEFDVRARDGGSPA 329
           D G +G+VT+ F     D++  LF L+  +G +T+LG LD+E   +Y+ DV A DG  P 
Sbjct: 270 DEGANGDVTYSFR-KVRDKISQLFQLNSLSGDITILGGLDYEDSGFYDIDVEAHDG--PG 326

Query: 330 MEQHCSLRVDLLDVNDNAPYITVTSELGTLPESAEPGTVVALISVQDPDSGSNGDVSLRI 389
           +     + V +LD NDNAP +TVTS   ++ ES+ PGTV+AL +V D DSG NG V+  I
Sbjct: 327 LRARSKVLVTVLDENDNAPEVTVTSLTSSVQESSSPGTVIALFNVHDSDSGGNGLVTCSI 386

Query: 390 PDHLPFALKSAFRNQFSLVTAGPLDREAKSSYDIMVTASDAGNPPLSTHRTIFLNISDVN 449
           PD+LPF L+  + N + L+T   LDRE  S Y+I VTA+D G PPLST   I L + D+N
Sbjct: 387 PDNLPFTLEKTYGNYYRLLTHRTLDREEVSEYNITVTATDQGTPPLSTETHISLQVMDIN 446

Query: 450 DNPPSFFQRSHEVFVPENNRPGDLLCSLAASDPDSGLNALISYSLLEPRNRDVSASSFIS 509
           DNPP+F   S+  ++PENN  G  + S+ A DPDSG NA I+YSL E   +    SS++S
Sbjct: 447 DNPPTFPHASYSAYIPENNPRGASILSMTAQDPDSGDNARITYSLAEDTFQGAPLSSYVS 506

Query: 510 LNPQTGAVHATRSFDYEQTQTLQFEVQARDRGNPPLSSTVTVRLFVLDLNDNAPAVLRPR 569
           +N  TG ++A  SFDYEQ + LQ  + A D G+PPLSS V++ LFVLD NDN P +L P 
Sbjct: 507 INSNTGILYALCSFDYEQFRDLQLLMTASDSGDPPLSSNVSLSLFVLDQNDNVPEILYPT 566

Query: 570 -ARPGSLCPQALPPSVGAGHLITKVTAVDLDSGYNAWVSYQLLEAPDPSLFAVSRYAGEV 628
               GS   +  P S  +G+L+TKV AVD DSG NAW+SY LL++ +P LFAV  + GEV
Sbjct: 567 FPTDGSTGVELAPRSADSGYLVTKVVAVDRDSGQNAWLSYSLLKSSEPGLFAVGLHTGEV 626

Query: 629 RTA-VPIPADLPPQKLVIVVKDSGSPPLSTSVTLLVSLEEDTHPVVPDL---RESSAPRE 684
           RTA   +  D   Q+LV+VV+D G PPLS +VTL V++ +    V+ DL   + S+ P  
Sbjct: 627 RTARALLDRDALKQRLVVVVQDHGQPPLSATVTLTVAVADSIPDVLADLGSLKPSADP-- 684

Query: 685 GESRLTLYLAVSLVAICFVSFGSFVALLSKCLRGAACGVTCFPAGTCACLTRSRRREGLP 744
            +S LTLYL V++ A+  V       LL+  LR           G+        R  G+P
Sbjct: 685 DDSGLTLYLVVAVAAVSCVFLAFVTVLLALKLRRWHKSRLLHAEGS--------RLAGVP 736

Query: 745 PSNGILRIQLGSDDPIKFVDVGGHSHGCTP-------LASAPTRSDSFMMVKSPSAPMAG 797
            S+ +     G D    F+    H    T        + S P+ +D+ +  +S       
Sbjct: 737 ASHFV-----GVDGVRAFLQTYSHEVSLTADSRKSHLIFSQPSYADTLISRESC------ 785

Query: 798 EPVRPSCPPSDLLY-----GLEQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQFDTE 852
           E   P     DLL       L+QAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQFDTE
Sbjct: 786 EKSEPLLITQDLLETKGDPNLQQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQFDTE 845

Query: 853 MLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATLTN 912
           MLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATLTN
Sbjct: 846 MLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATLTN 905

Query: 913 AAGKRDGKAPAGGNGNKKKSGKKEKK 938
           AAGKRDGKAPAGGNGNKKKSGKKEKK
Sbjct: 906 AAGKRDGKAPAGGNGNKKKSGKKEKK 931


>gi|14277675 protocadherin gamma subfamily C, 3 isoform 1 precursor
           [Homo sapiens]
          Length = 934

 Score =  828 bits (2138), Expect = 0.0
 Identities = 452/934 (48%), Positives = 585/934 (62%), Gaps = 30/934 (3%)

Query: 17  LLFLFYHLGYVCGQIRYPVPEESQEGTFVGNVAQDFLLDTDSLSARRLQVAGEVNQRHFR 76
           +L L   L      I Y +PEE ++G  VGNV  +  LD  SLSARR +V    ++R F 
Sbjct: 19  VLLLLGALNKASTVIHYEIPEEREKGFAVGNVVANLGLDLGSLSARRFRVVSGASRRFFE 78

Query: 77  VDLDSGALLIKNPIDREALCGLSASCIVPLEFVTEGPLEMYRAEVEIVDVNDHAPRFPRQ 136
           V+ ++G + + + +DRE LCG   SC V LE V E PLE++  EV I D+ND+ P FP Q
Sbjct: 79  VNRETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFSVEVVIQDINDNNPAFPTQ 138

Query: 137 QLDLEIGEAAPPGQRFPLEKAQDADVGSNSISSYRLSSNEHFALDVKKRSDGSLVPELLL 196
           ++ LEI EA  PG RFPLE A D DVGSNS+ +Y LS NE+FAL V+ R D +   EL+L
Sbjct: 139 EMKLEISEAVAPGTRFPLESAHDPDVGSNSLQTYELSRNEYFALRVQTREDSTKYAELVL 198

Query: 197 EKPLDREKQSDYRLVLTAVDGGNPPRSGTAELRVSVLDVNDNAPAFQQSSYRISVLESAP 256
           E+ LDRE++   +LVLTA+DGG P  S +  + + VLD NDNAP F QS YR  VLE AP
Sbjct: 199 ERALDREREPSLQLVLTALDGGTPALSASLPIHIKVLDANDNAPVFNQSLYRARVLEDAP 258

Query: 257 AGMVLIQLNASDPDLGPSGNVTFYFSGHTPDRVRNLFSLHPTTGKLTLLGPLDFESENYY 316
           +G  ++Q+ A+D D GP+G + + F  H    VR LF+L   TG LT+ G LDFE    +
Sbjct: 259 SGTRVVQVLATDLDEGPNGEIIYSFGSHNRAGVRQLFALDLVTGMLTIKGRLDFEDTKLH 318

Query: 317 EFDVRARDGGSPAMEQHCSLRVDLLDVNDNAPYITVTSELGTLPESAEPGTVVALISVQD 376
           E  ++A+D G+     HC + V+++DVNDNAP ITVTS    +PE A  GTV+AL+SV D
Sbjct: 319 EIYIQAKDKGANPEGAHCKVLVEVVDVNDNAPEITVTSVYSPVPEDAPLGTVIALLSVTD 378

Query: 377 PDSGSNGDVSLRIPDHLPFALKSAFRNQFSLVTAGPLDREAKSSYDIMVTASDAGNPPLS 436
            D+G NG V+  +P  LPF+L S+ +N F+L T+  LDRE    Y++ +TA DAG P LS
Sbjct: 379 LDAGENGLVTCEVPPGLPFSLTSSLKNYFTLKTSADLDRETVPEYNLSITARDAGTPSLS 438

Query: 437 THRTIFLNISDVNDNPPSFFQRSHEVFVPENNRPGDLLCSLAASDPDSGLNALISYSLLE 496
               + + +SD+NDNPP   Q S++V++ ENN PG  + +L+  DPD+  NA +S+ LLE
Sbjct: 439 ALTIVRVQVSDINDNPPQSSQSSYDVYIEENNLPGAPILNLSVWDPDAPQNARLSFFLLE 498

Query: 497 PRNRDVSASSFISLNPQTGAVHATRSFDYEQTQTLQFEVQARDRGNPPLSSTVTVRLFVL 556
                     + ++N   G V +    DYE  +  +      D G P L++ ++V +FV 
Sbjct: 499 QGAETGLVGRYFTINRDNGIVSSLVPLDYEDRREFELTAHISDGGTPVLATNISVNIFVT 558

Query: 557 DLNDNAPAVLRPRARPGSLCPQALPPSVGAGHLITKVTAVDLDSGYNAWVSYQLLEAPDP 616
           D NDNAP VL P  RPG    + LP    AGHL+++V   D D+G+NAW+SY LL +P+ 
Sbjct: 559 DRNDNAPQVLYP--RPGGSSVEMLPRGTSAGHLVSRVVGWDADAGHNAWLSYSLLGSPNQ 616

Query: 617 SLFAVSRYAGEVRTAVPI-PADLPPQKLVIVVKDSGSPPLSTSVTLLVSLEEDTHPVVPD 675
           SLFA+  + G++ TA P+   D P Q L +++KD+G P LST+ TL VS+ ED+     +
Sbjct: 617 SLFAIGLHTGQISTARPVQDTDSPRQTLTVLIKDNGEPSLSTTATLTVSVTEDSPEARAE 676

Query: 676 LRESSAPREGESRLTLYLAVSLVAICFVSFGSFVALLSKCLRGAACGVTCFPAGTCACLT 735
               SAPRE +  LT YL +SL+    VS G  V +          GV  F         
Sbjct: 677 FPSGSAPREQKKNLTFYLLLSLI---LVSVGFVVTVF---------GVIIFK----VYKW 720

Query: 736 RSRRREGLPPSNGILRIQLGS--DDPIKFVDVGGHSHGCTPLASAPTRSDSFMMVKSPSA 793
           +  R     P + + R    S   D ++   +  H +    L +   RSD  +     ++
Sbjct: 721 KQSRDLYRAPVSSLYRTPGPSLHADAVRGGLMSPHLYHQVYLTTDSRRSDPLLKKPGAAS 780

Query: 794 PMAG-EPVRPSCPPSDLLYGL--------EQAPPNTDWRFSQAQRPGTSGSQNGDDTGTW 844
           P+A  +    SC P      L        +QAPPNTDWRFSQAQRPGTSGSQNGDDTGTW
Sbjct: 781 PLASRQNTLRSCDPVFYRQVLGAESAPPGQQAPPNTDWRFSQAQRPGTSGSQNGDDTGTW 840

Query: 845 PNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIP 904
           PNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIP
Sbjct: 841 PNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIP 900

Query: 905 GSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK 938
           GSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK
Sbjct: 901 GSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK 934


>gi|11128031 protocadherin gamma subfamily B, 5 isoform 1 precursor
           [Homo sapiens]
          Length = 923

 Score =  825 bits (2132), Expect = 0.0
 Identities = 443/930 (47%), Positives = 593/930 (63%), Gaps = 53/930 (5%)

Query: 27  VCGQIRYPVPEESQEGTFVGNVAQDFLLDTDSLSARRLQVAGEVNQRHFRVDLDSGALLI 86
           +C QIRY +PEE  +G+ VGN+A D       L  R+L+V+ E  + +F V  +SG LL+
Sbjct: 29  LCEQIRYRIPEEMPKGSVVGNLATDLGFSVQELPTRKLRVSSE--KPYFTVSAESGELLV 86

Query: 87  KNPIDREALCGLSASCIVPLEFVTEGPLEMYRAEVEIVDVNDHAPRFPRQQLDLEIGEAA 146
            + +DRE +CG   +C +  E V E PL  Y   VEI D+NDH P+F +   +L+I E+A
Sbjct: 87  SSRLDREEICGKKPACALEFEAVAENPLNFYHVNVEIEDINDHTPKFTQNSFELQISESA 146

Query: 147 PPGQRFPLEKAQDADVGSNSISSYRLSSNEHFALDVKKRSDGSLVPELLLEKPLDREKQS 206
            PG RF LE A+DAD+G NS+  Y+LS N  F+L +K++ DGS  PEL LEK LDRE+QS
Sbjct: 147 QPGTRFILEVAEDADIGLNSLQKYKLSLNPSFSLIIKEKQDGSKYPELALEKTLDREQQS 206

Query: 207 DYRLVLTAVDGGNPPRSGTAELRVSVLDVNDNAPAFQQSSYRISVLESAPAGMVLIQLNA 266
            +RLVLTA+DGG+PP SGT ELR+ V D NDN P F +  YR+S+ E+ P G  ++Q++A
Sbjct: 207 YHRLVLTALDGGHPPLSGTTELRIQVTDANDNPPVFNRDVYRVSLRENVPPGTTVLQVSA 266

Query: 267 SDPDLGPSGNVTFYFSGHTPDRVRNLFSLHPTTGKLTLLGPLDFESENYYEFDVRARDGG 326
           +D D G +  +T+ F      R   +FSL+  +G++T    LDFE    Y   V  RDGG
Sbjct: 267 TDQDEGINSEITYSFY-----RTGQIFSLNSKSGEITTQKKLDFEETKEYSMVVEGRDGG 321

Query: 327 SPAMEQHCSLRVDLLDVNDNAPYITVTSELGTLPESAEPGTVVALISVQDPDSGSNGDVS 386
              +   C++ +++ D NDN+P +T  S L  + E+A PGT++ALI + D DSG NG+V+
Sbjct: 322 G--LVAQCTVEINIQDENDNSPEVTFHSLLEMILENAVPGTLIALIKIHDQDSGENGEVN 379

Query: 387 LRIPDHLPFALKSAFRNQFSLVTAGPLDREAKSSYDIMVTASDAGNPPLSTHRTIFLNIS 446
            ++   +PF + S+ +N + LVT G LDRE    Y++ +TA+D G PPLS+  ++ L+I 
Sbjct: 380 CQLQGEVPFKIISSSKNSYKLVTDGTLDREQTPEYNVTITATDRGKPPLSSSISVILHIR 439

Query: 447 DVNDNPPSFFQRSHEVFVPENNRPGDLLCSLAASDPDSGLNALISYSLLEPRNRDVSASS 506
           DVNDN P F Q S+ V VPENN PG  +  + ASD D GLN  +SYS++      ++ +S
Sbjct: 440 DVNDNAPVFHQASYLVSVPENNPPGASIAQVCASDLDLGLNGQVSYSIMASDLEPLALAS 499

Query: 507 FISLNPQTGAVHATRSFDYEQTQTLQFEVQARDRGNPPLSSTVTVRLFVLDLNDNAPAVL 566
           ++S++ Q+G V A R+FDYEQ +T +  +QARD+G+P LS+ V++R+ V D NDNAP VL
Sbjct: 500 YVSMSAQSGVVFAQRAFDYEQLRTFELTLQARDQGSPALSANVSLRVLVGDRNDNAPRVL 559

Query: 567 RPRARP-GSLCPQALPPSVGAGHLITKVTAVDLDSGYNAWVSYQLLEAPDPSLFAVSRYA 625
            P   P GS     +P +   G+L+TKV AVD DSG+NAW+SY +L+A +P LF++    
Sbjct: 560 YPALGPDGSALFDMVPRAAEPGYLVTKVVAVDADSGHNAWLSYHVLQASEPGLFSLGLRT 619

Query: 626 GEVRTAVPI-PADLPPQKLVIVVKDSGSPPLSTSVTLLVSLEEDTHPVVPDLRESSAPRE 684
           GEVRTA  +   D   Q+L++ V+D G PPLS + TL +   +    V+PD+ +   P +
Sbjct: 620 GEVRTARALGDRDAARQRLLVAVRDGGQPPLSATATLHLVFADSLQEVLPDITDRPVPSD 679

Query: 685 GESRLTLYLAVSLVAICFVSFGSFVALLSKCLRGAACGV--TCFPAGTCACLTRSRRREG 742
            ++ L  YL V+L  I  +   + +  ++  LR ++     +CF  G C      +    
Sbjct: 680 PQAELQFYLVVALALISVLFLLAVILAVALRLRRSSSPAAWSCFQPGLCV-----KSGPV 734

Query: 743 LPPSNGILRIQLGSDDPIKFVDVGGHSHGCTP----LASAPTRSDSFMMVKSPSAPMAGE 798
           +PP+                     +S G  P    L  A T    F  +K      +G+
Sbjct: 735 VPPN---------------------YSQGTLPYSYNLCVAHTGKTEFNFLKCSEQLSSGQ 773

Query: 799 PVR---------PSCPPSDLLYGLE-QAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQ 848
            +          P C  S+     E QAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQ
Sbjct: 774 DILCGDSSGALFPLCNSSESTSHPELQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQ 833

Query: 849 FDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNA 908
           FDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNA
Sbjct: 834 FDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNA 893

Query: 909 TLTNAAGKRDGKAPAGGNGNKKKSGKKEKK 938
           TLTNAAGKRDGKAPAGGNGNKKKSGKKEKK
Sbjct: 894 TLTNAAGKRDGKAPAGGNGNKKKSGKKEKK 923


>gi|11128037 protocadherin gamma subfamily B, 1 isoform 1 precursor
           [Homo sapiens]
          Length = 927

 Score =  819 bits (2115), Expect = 0.0
 Identities = 450/944 (47%), Positives = 596/944 (63%), Gaps = 57/944 (6%)

Query: 17  LLFLFYHLGYVCGQIRYPVPEESQEGTFVGNVAQDFLLDTDSLSARRLQVAGEVNQRHFR 76
           LL LF   G +  QIRY +PEE   G+ VG +A+D  L    L  R+L+V+ E    +F 
Sbjct: 19  LLSLF--CGAISQQIRYTIPEELANGSRVGKLAKDLGLSVRELPTRKLRVSAE---DYFN 73

Query: 77  VDLDSGALLIKNPIDREALCGLSASCIVPLEFVTEGPLEMYRAEVEIVDVNDHAPRFPRQ 136
           V L+SG LL+   IDRE +CG    C +  E V E P+ ++   V I D+ND+APRF  +
Sbjct: 74  VSLESGDLLVNGRIDREKICGRKLECALEFETVAENPMNVFHVVVVIQDINDNAPRFVAK 133

Query: 137 QLDLEIGEAAPPGQRFPLEKAQDADVGSNSISSYRLSSNEHFALDVKKRSDGSLVPELLL 196
            +DLEI E+A PG +F L+ AQDADV  NS+  Y ++ N++F+L  K+  DGS  P LLL
Sbjct: 134 GIDLEICESALPGVKFSLDSAQDADVEGNSLKLYTINPNQYFSLSTKESPDGSKYPVLLL 193

Query: 197 EKPLDREKQSDYRLVLTAVDGGNPPRSGTAELRVSVLDVNDNAPAFQQSSYRISVLESAP 256
           EKPLDRE QS +RL+LTA+DGG+PP SGT  + + V D NDNAP F Q  YR+S+ E+ P
Sbjct: 194 EKPLDREHQSSHRLILTAMDGGDPPLSGTTHIWIRVTDANDNAPVFSQEVYRVSLQENVP 253

Query: 257 AGMVLIQLNASDPDLGPSGNVTFYFSGHTPDRVRNLFSLHPTTGKLTLLGPLDFESENYY 316
            G  ++++ A+D D G +  +T+ F         +LF+L+P TG +T  G LDFE  + Y
Sbjct: 254 WGTSVLRVMATDQDEGINAEITYAFLNSPIST--SLFNLNPNTGDITTNGTLDFEETSRY 311

Query: 317 EFDVRARDGGSPAMEQHCSLRVDLLDVNDNAPYITVTSELGTLPESAEPGTVVALISVQD 376
              V A+DGG      HC+++++++D NDNAP +T  S    +PE ++ GTV+ALI V+D
Sbjct: 312 VLSVEAKDGG--VHTAHCNVQIEIVDENDNAPEVTFMSFSNQIPEDSDLGTVIALIKVRD 369

Query: 377 PDSGSNGDVSLRIPDHLPFALKSAFRNQFSLVTAGPLDREAKSSYDIMVTASDAGNPPLS 436
            DSG NG V+    + +PF L+S  +N + LV AG L+RE  + Y++ + A+D G P LS
Sbjct: 370 KDSGQNGMVTCYTQEEVPFKLESTSKNYYKLVIAGALNREQTADYNVTIIATDKGKPALS 429

Query: 437 THRTIFLNISDVNDNPPSFFQRSHEVFVPENNRPGDLLCSLAASDPDSGLNALISYSLLE 496
           +  +I L+ISD+NDN P F Q S+ V V ENN PG  +  ++ASDPD G N  +SYS+L 
Sbjct: 430 SRTSITLHISDINDNAPVFHQASYVVHVSENNPPGASIAQVSASDPDLGPNGRVSYSILA 489

Query: 497 PRNRDVSASSFISLNPQTGAVHATRSFDYEQTQTLQFEVQARDRGNPPLSSTVTVRLFVL 556
                    S++S++PQ+G V A R+FD+EQ +  +  +QARD+G+P LS+ V++R+ V 
Sbjct: 490 SDLEPRELLSYVSVSPQSGVVFAQRAFDHEQLRAFELTLQARDQGSPALSANVSLRVLVG 549

Query: 557 DLNDNAPAVLRPRARP-GSLCPQALPPSVGAGHLITKVTAVDLDSGYNAWVSYQLLEAPD 615
           DLNDNAP VL P   P GS     +P +   G+L+TKV AVD DSG+NAW+SY +L+A +
Sbjct: 550 DLNDNAPRVLYPALGPDGSALFDMVPRAAEPGYLVTKVVAVDADSGHNAWLSYHVLQASE 609

Query: 616 PSLFAVSRYAGEVRTAVPI-PADLPPQKLVIVVKDSGSPPLSTSVTLLVSLEEDTHPVVP 674
           P LF++    GEVRTA  +   D   Q+L++ V+D G PPLS + TL +   +    V+P
Sbjct: 610 PGLFSLGLRTGEVRTARALGDRDAARQRLLVAVRDGGQPPLSATATLHLIFADSLQEVLP 669

Query: 675 DLRESSAPREGESRLTLYLAVSLVAICFVSFGSFVALLSKCLRGAACGVT--CFPAGTCA 732
           DL +   P + ++ L  YL V+L  I  +   + +  ++  LR ++   T  CF  G C 
Sbjct: 670 DLSDRPEPSDPQTELQFYLVVALALISVLFLLAVILAIALRLRRSSSLDTEGCFQTGLC- 728

Query: 733 CLTRSRRREGLPPSNGILRIQLGSDDPIKFVDVGGHSHGCTPLA--------SAPTRSDS 784
               S+   G+PP+                     HS G  P +        SA T  +S
Sbjct: 729 ----SKSGPGVPPN---------------------HSEGTLPYSYNLCIASHSAKTEFNS 763

Query: 785 FMMVKSPSAP---MAGEPVRPSCPPS-------DLLYGLEQAPPNTDWRFSQAQRPGTSG 834
             +    + P   +  +P    C  +       D      QAPPNTDWRFSQAQRPGTSG
Sbjct: 764 LNLTPEMAPPQDLLCDDPSMVVCASNEDHKIAYDPSLSSHQAPPNTDWRFSQAQRPGTSG 823

Query: 835 SQNGDDTGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHV 894
           SQNGDDTGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHV
Sbjct: 824 SQNGDDTGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHV 883

Query: 895 PDYRQNVYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK 938
           PDYRQNVYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK
Sbjct: 884 PDYRQNVYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK 927


>gi|11056024 protocadherin gamma subfamily A, 5 isoform 1 precursor
           [Homo sapiens]
          Length = 931

 Score =  816 bits (2108), Expect = 0.0
 Identities = 460/943 (48%), Positives = 596/943 (63%), Gaps = 35/943 (3%)

Query: 12  WRWATLLFLFYHLGYVC----GQIRYPVPEESQEGTFVGNVAQDFLLDTDSLSARRLQVA 67
           W    LL  F  LG +C    GQIRY +PEE  +G+FVGN+A+D  L+   L+ R +++ 
Sbjct: 8   WGCGELLLPFMLLGTLCEPGSGQIRYSMPEELDKGSFVGNIAKDLGLEPQELAERGVRIV 67

Query: 68  GEVNQRHFRVDLDSGALLIKNPIDREALCGLSASCIVPLEFVTEGPLEMYRAEVEIVDVN 127
                + F ++  SG+L+    IDRE LC  S  C+V    + E  +++Y  EVEI+D+N
Sbjct: 68  SRGRTQLFALNPRSGSLVTAGRIDREELCAQSPLCVVNFNILVENKMKIYGVEVEIIDIN 127

Query: 128 DHAPRFPRQQLDLEIGEAAPPGQRFPLEKAQDADVGSNSISSYRLSSNEHFALDVKKRSD 187
           D+ PRF  ++L +++ E A  G R  L  A+DADVG NS+ SY+LSSN HF+LDV   +D
Sbjct: 128 DNFPRFRDEELKVKVNENAAAGTRLVLPFARDADVGVNSLRSYQLSSNLHFSLDVVSGTD 187

Query: 188 GSLVPELLLEKPLDREKQSDYRLVLTAVDGGNPPRSGTAELRVSVLDVNDNAPAFQQSSY 247
           G   PEL+LE+PLDREK++ + L+LTA+DGG+P  SGT  +RV+VLD NDNAP F  S Y
Sbjct: 188 GQKYPELVLEQPLDREKETVHDLLLTALDGGDPVLSGTTHIRVTVLDANDNAPLFTPSEY 247

Query: 248 RISVLESAPAGMVLIQLNASDPDLGPSGNVTFYFSGHTPDRVRNLFSLHPTTGKLTLLGP 307
            +SV E+ P G  L+ L A+DPD G +G +T+ F  +  +++   F L    G+++ L  
Sbjct: 248 SVSVPENIPVGTRLLMLTATDPDEGINGKLTYSFR-NEEEKISETFQLDSNLGEISTLQS 306

Query: 308 LDFESENYYEFDVRARDGGSPAMEQHCSLRVDLLDVNDNAPYITVTSELGTLPESAEPGT 367
           LD+E   +Y  +V A+DGG  A+     + V + DVNDNAP + +TS   ++ E   PGT
Sbjct: 307 LDYEESRFYLMEVVAQDGG--ALVASAKVVVTVQDVNDNAPEVILTSLTSSISEDCLPGT 364

Query: 368 VVALISVQDPDSGSNGDVSLRIPDHLPFALKSAFRNQFSLVTAGPLDREAKSSYDIMVTA 427
           V+AL SV D DSG NG+++  IP +LPF L+ +  N + L+T   LDRE  S Y+I +T 
Sbjct: 365 VIALFSVHDGDSGENGEIACSIPRNLPFKLEKSVDNYYHLLTTRDLDREETSDYNITLTV 424

Query: 428 SDAGNPPLSTHRTIFLNISDVNDNPPSFFQRSHEVFVPENNRPGDLLCSLAASDPDSGLN 487
            D G PPLST   I L ++DVNDNPP+F Q S+   V ENN  G  + S+ A DPDSG N
Sbjct: 425 MDHGTPPLSTESHIPLKVADVNDNPPNFPQASYSTSVTENNPRGVSIFSVTAHDPDSGDN 484

Query: 488 ALISYSLLEPRNRDVSASSFISLNPQTGAVHATRSFDYEQTQTLQFEVQARDRGNPPLSS 547
           A ++YSL E   +    SS++S+N  TG ++A RSFDYEQ + LQ  V A D GNPPLSS
Sbjct: 485 ARVTYSLAEDTFQGAPLSSYVSINSDTGVLYALRSFDYEQLRDLQLWVTASDSGNPPLSS 544

Query: 548 TVTVRLFVLDLNDNAPAVLRPR-ARPGSLCPQALPPSVGAGHLITKVTAVDLDSGYNAWV 606
            V++ LFVLD NDN P +L P     GS   +  P S   G+L+TKV AVD DSG NAW+
Sbjct: 545 NVSLSLFVLDQNDNTPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDKDSGQNAWL 604

Query: 607 SYQLLEAPDPSLFAVSRYAGEVRTA-VPIPADLPPQKLVIVVKDSGSPPLSTSVTLLVSL 665
           SY+LL+A +P LFAV  + GEVRTA   +  D   Q LV+ V+D G PPLS + T+ V++
Sbjct: 605 SYRLLKASEPGLFAVGLHTGEVRTARALLDRDALKQSLVVAVEDHGQPPLSATFTVTVAV 664

Query: 666 EEDTHPVVPDLRESSAPREGES-RLTLYLAVSLVAICFVSFGSFVALLSKCLRGAACGVT 724
            +    ++ DL     P + E   LTLYL V++ A+  V     + LL   LR       
Sbjct: 665 ADRIPDILADLGSIKTPIDPEDLDLTLYLVVAVAAVSCVFLAFVIVLLVLRLRRWHKSRL 724

Query: 725 CFPAGTCACLTRSRRREGLPPSNGILRIQLGSDDPIKFVDVGGHSHGCTP-------LAS 777
               G+        R  G+P S+ +     G D    F+    H    T        +  
Sbjct: 725 LQAEGS--------RLAGVPASHFV-----GVDGVRAFLQTYSHEVSLTADSRKSHLIFP 771

Query: 778 APTRSDSFMMVKS--PSAPMAGEPVRPSCPPSDLLYGLEQAPPNTDWRFSQAQRPGTSGS 835
            P  +D+ +  +S   S P+    +      +     ++QAPPNTDWRFSQAQRPGTSGS
Sbjct: 772 QPNYADTLLSEESCEKSEPLL---MSDKVDANKEERRVQQAPPNTDWRFSQAQRPGTSGS 828

Query: 836 QNGDDTGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVP 895
           QNGDDTGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVP
Sbjct: 829 QNGDDTGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVP 888

Query: 896 DYRQNVYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK 938
           DYRQNVYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK
Sbjct: 889 DYRQNVYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK 931


>gi|11056065 protocadherin gamma subfamily A, 6 isoform 1 precursor
           [Homo sapiens]
          Length = 932

 Score =  813 bits (2099), Expect = 0.0
 Identities = 462/939 (49%), Positives = 591/939 (62%), Gaps = 56/939 (5%)

Query: 25  GYVCGQIRYPVPEESQEGTFVGNVAQDFLLDTDSLSARRLQVAGEVNQRHFRVDLDSGAL 84
           G    QIRY +PEE ++G+FVGN+ +D  L+   L+   +++      + F ++  +G+L
Sbjct: 25  GAAAAQIRYSIPEELEKGSFVGNIVKDLGLEPQELAEHGVRIVSRGRMQLFSLNPRNGSL 84

Query: 85  LIKNPIDREALCGLSASCIVPLEFVTEGPLEMYRAEVEIVDVNDHAPRFPRQQLDLEIGE 144
           +    IDRE LC  S  C+V    + E  L +Y  EVEIVD+ND+ PRF +++L+++I E
Sbjct: 85  VTAGRIDREELCAQSPRCLVSFNILVEDKLNLYPVEVEIVDINDNTPRFLKEELEVKILE 144

Query: 145 AAPPGQRFPLEKAQDADVGSNSISSYRLSSNEHFALDVKKRSDGSLVPELLLEKPLDREK 204
            A P  RFPL +  D DVG NS+  ++LS N HF++DV+  + G   PEL+LE  LDRE 
Sbjct: 145 NAAPSSRFPLMEVYDPDVGMNSLQGFKLSGNSHFSVDVQSEAHGPKYPELVLEGTLDREG 204

Query: 205 QSDYRLVLTAVDGGNPPRSGTAELRVSVLDVNDNAPAFQQSSYRISVLESAPAGMVLIQL 264
           ++ YRLVLTA+DGG+P RS  A++ V+VLDVNDN P F Q  YR+SV E+ P G  ++ +
Sbjct: 205 EAVYRLVLTAMDGGDPVRSSVAQILVTVLDVNDNTPMFTQPVYRVSVPENLPVGTPVLAV 264

Query: 265 NASDPDLGPSGNVTFYFSGHTPDRVRNLFSLHPTTGKLTLLGPLDFESENYYEFDVRARD 324
            A+D D G  G VT+ F   T +++  +F L+  TG+++    LD+E  ++YE  V ARD
Sbjct: 265 TATDQDEGVHGEVTYSFVKIT-EKISQIFCLNVLTGEISTSANLDYEDSSFYELGVEARD 323

Query: 325 GGSPAMEQHCSLRVDLLDVNDNAPYITVTSELGTLPESAEPGTVVALISVQDPDSGSNGD 384
           G  P +     + + +LDVNDN P + VTS   T+ ESA PGTV+AL  V D DSG NG 
Sbjct: 324 G--PGLRDRAKVLITILDVNDNVPEVVVTSGSRTIAESAPPGTVIALFQVFDRDSGLNGL 381

Query: 385 VSLRIPDHLPFALKSAFRNQFSLVTAGPLDREAKSSYDIMVTASDAGNPPLSTHRTIFLN 444
           V+  IP  LPF L+ +  N + LVT   LDRE    Y+I VTA+D G PPLST   I LN
Sbjct: 382 VTCSIPRSLPFELEKSVGNYYRLVTNAALDREEVFLYNITVTATDKGTPPLSTETIISLN 441

Query: 445 ISDVNDNPPSFFQRSHEVFVPENNRPGDLLCSLAASDPDSGLNALISYSLLEPRNRDVSA 504
           ++D NDNPP+F   S+ V+V ENN  G  + S+ A DPD   NA +SYSL E   +    
Sbjct: 442 VADTNDNPPTFPHSSYSVYVLENNPRGASIFSVNALDPDVDQNAQVSYSLAEDTLQGAPL 501

Query: 505 SSFISLNPQTGAVHATRSFDYEQTQTLQFEVQARDRGNPPLSSTVTVRLFVLDLNDNAPA 564
           SS++S+N  TG ++A RSFDYEQ + LQ  V A D G+PPLSS V++ LFVLD NDNAP 
Sbjct: 502 SSYVSINSDTGILYALRSFDYEQLRDLQLWVTASDSGDPPLSSNVSLSLFVLDQNDNAPE 561

Query: 565 VLRPR-ARPGSLCPQALPPSVGAGHLITKVTAVDLDSGYNAWVSYQLLEAPDPSLFAVSR 623
           +L P     GS   +  P S   G+L+TKV AVD DSG NAW+SY+LL+A +P LF+V  
Sbjct: 562 ILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSYRLLKASEPGLFSVGL 621

Query: 624 YAGEVRTA-VPIPADLPPQKLVIVVKDSGSPPLSTSVTLLVSLEEDTHPVVPDLRE-SSA 681
           + GEVRTA   +  D   Q LV+ V+D G PPLS +VTL V++ +    ++ DL     +
Sbjct: 622 HTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADRIPDILADLGSLEPS 681

Query: 682 PREGESRLTLYLAVSLVAICFVSFGSFVALLSKCLRGAACGVTCFPAGTCACLTRSRRRE 741
            +  +S LTLYL V++ A+  V     + LL+  LR                L R  +  
Sbjct: 682 AKPNDSDLTLYLVVAVAAVSCVFLAFVIVLLA--LR----------------LQRWHKSR 723

Query: 742 GLPPSNGILRIQLGSDDPIKFVDVGG-------HSHGCTPLASA---------PTRSDSF 785
            L  S G L    GS     FV V G       +SH  +  A +         P  +D+ 
Sbjct: 724 LLQASGGGLASMPGS----HFVGVEGVRAFLQTYSHEVSLTADSRKSHLIFPQPNYADTL 779

Query: 786 MMVKSPSAPMAGEPVRPSCPPSDLL------YGLEQAPPNTDWRFSQAQRPGTSGSQNGD 839
           +  +S       E   P     DLL        L+QAPPNTDWRFSQAQRPGTSGSQNGD
Sbjct: 780 INQES------YEKSEPLLITQDLLETKGEPRQLQQAPPNTDWRFSQAQRPGTSGSQNGD 833

Query: 840 DTGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQ 899
           DTGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQ
Sbjct: 834 DTGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQ 893

Query: 900 NVYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK 938
           NVYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK
Sbjct: 894 NVYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK 932


>gi|14589880 protocadherin gamma subfamily A, 3 isoform 1 precursor
           [Homo sapiens]
          Length = 932

 Score =  811 bits (2095), Expect = 0.0
 Identities = 453/940 (48%), Positives = 592/940 (62%), Gaps = 52/940 (5%)

Query: 24  LGYVC----GQIRYPVPEESQEGTFVGNVAQDFLLDTDSLSARRLQVAGEVNQRHFRVDL 79
           LG +C    GQIRY V EE  +G+FVGN+A D  L+   L+ R +++      + F ++ 
Sbjct: 20  LGTLCETGSGQIRYSVSEELDKGSFVGNIANDLGLEPRELAERGVRIVSRGRTQLFSLNP 79

Query: 80  DSGALLIKNPIDREALCGLSASCIVPLEFVTEGPLEMYRAEVEIVDVNDHAPRFPRQQLD 139
            SG+L+    IDRE LC     C+V +  + E  L+++  E+EI D+ND+AP FP ++L+
Sbjct: 80  QSGSLVTAERIDREELCAQIPLCLVKINILVEDKLKIFEVEIEIKDINDNAPNFPTEELE 139

Query: 140 LEIGEAAPPGQRFPLEKAQDADVGSNSISSYRLSSNEHFALDVKKRSDGSLVPELLLEKP 199
           ++IGE   PG RFP++ A D DVG NS+ +Y+LS N++F+L V   S+G+  PEL+LE+ 
Sbjct: 140 IKIGELTVPGTRFPIKTAFDPDVGINSLQNYKLSPNDYFSLAVNSVSEGAKYPELVLERA 199

Query: 200 LDREKQSDYRLVLTAVDGGNPPRSGTAELRVSVLDVNDNAPAFQQSSYRISVLESAPAGM 259
           LDREK+  ++LVL A DGG+P  SG   ++V VLD NDN P F Q  YR+SV E+ P G 
Sbjct: 200 LDREKKEIHQLVLVASDGGDPVHSGNLHIQVIVLDANDNPPMFTQPEYRVSVWENVPVGT 259

Query: 260 VLIQLNASDPDLGPSGNVTFYFSGHTPDRVRNLFSLHPTTGKLTLLGPLDFESENYYEFD 319
            L+ +NA+DPD G +  V+ Y     P ++  +F L+  +G++++L  LD+E   +YE  
Sbjct: 260 RLLTVNATDPDEGFNAQVS-YILDKMPGKIAEIFHLNSVSGEVSILKSLDYEDAMFYEIK 318

Query: 320 VRARDGGSPAMEQHCSLRVDLLDVNDNAPYITVTSELGTLPESAEPGTVVALISVQDPDS 379
           + A+DG  P +     + V +LDVNDNAP IT+TS   ++PE    G  +ALI V D DS
Sbjct: 319 IEAQDG--PGLLSRAKILVTVLDVNDNAPEITITSLTSSVPEEGTVGREIALIDVHDRDS 376

Query: 380 GSNGDVSLRIPDHLPFALKSAFRNQFSLVTAGPLDREAKSSYDIMVTASDAGNPPLSTHR 439
           G NG V + +  +LPF L+ +    + LVTA  LDRE  S Y+I + ASD G+PPLST  
Sbjct: 377 GQNGQVEVFVLGNLPFKLEKSIDQYYRLVTATSLDREQISEYNISLRASDGGSPPLSTET 436

Query: 440 TIFLNISDVNDNPPSFFQRSHEVFVPENNRPGDLLCSLAASDPDSGLNALISYSLLEPRN 499
            I L++ D+NDNPP+F   S+  ++PENN  G  + S+ A DPDS  NA I+Y+L E   
Sbjct: 437 HITLHVIDINDNPPTFPHLSYSAYIPENNPRGASIFSVTAQDPDSNNNARITYALTEDTL 496

Query: 500 RDVSASSFISLNPQTGAVHATRSFDYEQTQTLQFEVQARDRGNPPLSSTVTVRLFVLDLN 559
           +    SSF+S+N  TG ++A RSFDYEQ + L+  V A D GNPPLSS V++ LFVLD N
Sbjct: 497 QGAPLSSFVSINSNTGVLYALRSFDYEQFRDLKLLVTASDSGNPPLSSNVSLNLFVLDQN 556

Query: 560 DNAPAVLRPR-ARPGSLCPQALPPSVGAGHLITKVTAVDLDSGYNAWVSYQLLEAPDPSL 618
           DNAP +L P     GS   +  P S   G+L+TKV AVD DSG NAW+SY+LL+A +P L
Sbjct: 557 DNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSYRLLKASEPGL 616

Query: 619 FAVSRYAGEVRTA-VPIPADLPPQKLVIVVKDSGSPPLSTSVTLLVSLEEDTHPVVPDLR 677
           F+V  + GEVRTA   +  D   Q LV+ V+D G PPLS +VTL V++ +    ++ DL 
Sbjct: 617 FSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADRIPDILADLG 676

Query: 678 E-SSAPREGESRLTLYLAVSLVAICFVSFGSFVALLSKCLRGAACGVTCFPAGTCACLTR 736
               + +  +S LTLYL V++ A+  V     + LL+  LR                  R
Sbjct: 677 SLEPSAKPNDSDLTLYLVVAVAAVSCVFLAFVIVLLALRLR------------------R 718

Query: 737 SRRREGLPPSNGILRIQ-----LGSDDPIKFVDVGGHSHGCTP-------LASAPTRSDS 784
             +   L  S G L        +G+D    F+    H    T        +   P  +D+
Sbjct: 719 WHKSRLLQASGGGLASTPGSHFVGADGVRAFLQTYSHEVSLTADSRKSHLIFPQPNYADT 778

Query: 785 FMMVKSPSAPMAGEPVRPSCPPSDLLYG------LEQAPPNTDWRFSQAQRPGTSGSQNG 838
            +  +S       E   P     DLL        L+QAPPNTDWRFSQAQRPGTSGSQNG
Sbjct: 779 LISQES------CEKSEPLLITQDLLEMKGDSNLLQQAPPNTDWRFSQAQRPGTSGSQNG 832

Query: 839 DDTGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYR 898
           DDTGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYR
Sbjct: 833 DDTGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYR 892

Query: 899 QNVYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK 938
           QNVYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK
Sbjct: 893 QNVYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK 932


>gi|11056032 protocadherin gamma subfamily A, 1 isoform 1 precursor
           [Homo sapiens]
          Length = 931

 Score =  805 bits (2080), Expect = 0.0
 Identities = 450/929 (48%), Positives = 585/929 (62%), Gaps = 45/929 (4%)

Query: 29  GQIRYPVPEESQEGTFVGNVAQDFLLDTDSLSARRLQVAGEVNQRHFRVDLDSGALLIKN 88
           G I Y VPEE+ +G+FVGN+A+D  L    L+   +++        F ++  SG+L+   
Sbjct: 29  GNIHYSVPEETDKGSFVGNIAKDLGLQPQELADGGVRIVSRGRMPLFALNPRSGSLITAR 88

Query: 89  PIDREALCGLSASCIVPLEFVTEGPLEMYRAEVEIVDVNDHAPRFPRQQLDLEIGEAAPP 148
            IDRE LC  S  C+V    + E  ++++  EVEI+D+ND+ P+F  ++L+ ++ E   P
Sbjct: 89  RIDREELCAQSMPCLVSFNILVEDKMKLFPVEVEIIDINDNTPQFQLEELEFKMNEITTP 148

Query: 149 GQRFPLEKAQDADVGSNSISSYRLSSNEHFALDVKKRSDGSLVPELLLEKPLDREKQSDY 208
           G R  L   QD DVG NS+ SY+LSSN HF+LDV++ +DG   PE++L+ PLDRE+++ +
Sbjct: 149 GTRVSLPFGQDLDVGMNSLQSYQLSSNPHFSLDVQQGADGPQHPEMVLQSPLDREEEAVH 208

Query: 209 RLVLTAVDGGNPPRSGTAELRVSVLDVNDNAPAFQQSSYRISVLESAPAGMVLIQLNASD 268
            L+LTA DGG P RSGT  + + V+D NDN PAF Q+ Y I+V E+ P G  L+ +NA+D
Sbjct: 209 HLILTASDGGEPVRSGTLRIYIQVVDANDNPPAFTQAQYHINVPENVPLGTQLLMVNATD 268

Query: 269 PDLGPSGNVTFYFSGHTPD-RVRNLFSLHPTTGKLTLLGPLDFESENYYEFDVRARDGGS 327
           PD G +G VT+ F  H  D RV  +F L   TG+++   PLDFE    Y  +V+A+DG  
Sbjct: 269 PDEGANGEVTYSF--HNVDHRVAQIFRLDSYTGEISNKEPLDFEEYKMYSMEVQAQDGA- 325

Query: 328 PAMEQHCSLRVDLLDVNDNAPYITVTSELGTLPESAEPGTVVALISVQDPDSGSNGDVSL 387
             +     + + +LDVNDNAP +T+TS    +PE+  PGT++ALISV D DSG NG  + 
Sbjct: 326 -GLMAKVKVLIKVLDVNDNAPEVTITSVTTAVPENFPPGTIIALISVHDQDSGDNGYTTC 384

Query: 388 RIPDHLPFALKSAFRNQFSLVTAGPLDREAKSSYDIMVTASDAGNPPLSTHRTIFLNISD 447
            IP +LPF L+    N + LVT   LDRE  S Y+I +TA D G P LST   I L ++D
Sbjct: 385 FIPGNLPFKLEKLVDNYYRLVTERTLDRELISGYNITITAIDQGTPALSTETHISLLVTD 444

Query: 448 VNDNPPSFFQRSHEVFVPENNRPGDLLCSLAASDPDSGLNALISYSLLEPRNRDVSASSF 507
           +NDN P F Q S+  ++PENN  G  + S+ A D DS  NA I+YSL+E   +    S++
Sbjct: 445 INDNSPVFHQDSYSAYIPENNPRGASIFSVRAHDLDSNENAQITYSLIEDTIQGAPLSAY 504

Query: 508 ISLNPQTGAVHATRSFDYEQTQTLQFEVQARDRGNPPLSSTVTVRLFVLDLNDNAPAVLR 567
           +S+N  TG ++A RSFDYEQ + +Q +V ARD G+PPLSS V++ LF+LD NDNAP +L 
Sbjct: 505 LSINSDTGVLYALRSFDYEQFRDMQLKVMARDSGDPPLSSNVSLSLFLLDQNDNAPEILY 564

Query: 568 PR-ARPGSLCPQALPPSVGAGHLITKVTAVDLDSGYNAWVSYQLLEAPDPSLFAVSRYAG 626
           P     GS   +  P S   G+L+TKV AVD DSG NAW+SY+LL+A +P LF+V  + G
Sbjct: 565 PALPTDGSTGVELAPLSAEPGYLVTKVVAVDRDSGQNAWLSYRLLKASEPGLFSVGLHTG 624

Query: 627 EVRTA-VPIPADLPPQKLVIVVKDSGSPPLSTSVTLLVSLEEDTHPVVPDLRE-SSAPRE 684
           EVRTA   +  D   Q LV+ V+D G PPLS +VTL V++ +    ++ DL     + + 
Sbjct: 625 EVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADRISDILADLGSLEPSAKP 684

Query: 685 GESRLTLYLAVSLVAICFVSFGSFVALLSKCLRGAACGVTCFPAGTCACLTRSRRREGLP 744
            +S LTLYL V+  A+  V     + LL+  LR                  R  +   L 
Sbjct: 685 NDSDLTLYLVVAAAAVSCVFLAFVIVLLAHRLR------------------RWHKSRLLQ 726

Query: 745 PSNGILRIQLGSDDPIKFVDVGG-------HSHGCTPLASA-------PTRSDSFMMVKS 790
            S G L    GS     FV V G       +SH  +  A +       P  + +  ++  
Sbjct: 727 ASGGGLASMPGS----HFVGVDGVRAFLQTYSHEVSLTADSRKSHLIFPQPNYADTLISQ 782

Query: 791 PSAPMAGEPVRPSCPPSDLLYGL-EQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQF 849
            S    G    P     D      +QAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQF
Sbjct: 783 ESCEKKGFLSAPQSLLEDKKEPFSQQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQF 842

Query: 850 DTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNAT 909
           DTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNAT
Sbjct: 843 DTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNAT 902

Query: 910 LTNAAGKRDGKAPAGGNGNKKKSGKKEKK 938
           LTNAAGKRDGKAPAGGNGNKKKSGKKEKK
Sbjct: 903 LTNAAGKRDGKAPAGGNGNKKKSGKKEKK 931


>gi|13470082 protocadherin gamma subfamily B, 4 isoform 1 precursor
           [Homo sapiens]
          Length = 923

 Score =  805 bits (2080), Expect = 0.0
 Identities = 439/929 (47%), Positives = 583/929 (62%), Gaps = 51/929 (5%)

Query: 27  VCGQIRYPVPEESQEGTFVGNVAQDFLLDTDSLSARRLQVAGEVNQRHFRVDLDSGALLI 86
           +C QIRY +PEE  +G+ VGN+A D       L  R+L+V+ E  + +F V  +SG LL+
Sbjct: 29  LCEQIRYRIPEEMPKGSVVGNLATDLGFSVQELPTRKLRVSSE--KPYFTVSAESGELLV 86

Query: 87  KNPIDREALCGLSASCIVPLEFVTEGPLEMYRAEVEIVDVNDHAPRFPRQQLDLEIGEAA 146
            + +DRE +CG   +C +  E V E PL  Y   VEI D+NDH P+F +   +L+I E+A
Sbjct: 87  SSRLDREEICGKKPACALEFEAVAENPLNFYHVNVEIEDINDHTPKFTQNSFELQISESA 146

Query: 147 PPGQRFPLEKAQDADVGSNSISSYRLSSNEHFALDVKKRSDGSLVPELLLEKPLDREKQS 206
            PG RF L  A DAD+GSN++ +Y+LS ++HF+L  K++SDGS  PE++L+ PLDREKQ 
Sbjct: 147 QPGTRFILGSAHDADIGSNTLQNYQLSPSDHFSLINKEKSDGSKYPEMVLKTPLDREKQK 206

Query: 207 DYRLVLTAVDGGNPPRSGTAELRVSVLDVNDNAPAFQQSSYRISVLESAPAGMVLIQLNA 266
            Y L LTA+D G PP S TA++ V V D NDNAP F Q  YR+S+ E+   G  ++Q+ A
Sbjct: 207 SYHLTLTALDFGAPPLSSTAQIHVLVTDANDNAPVFSQDVYRVSLSENVYPGTTVLQVTA 266

Query: 267 SDPDLGPSGNVTFYFSGHTPDRVRNLFSLHPTTGKLTLLGPLDFESENYYEFDVRARDGG 326
           +D D G +  +TF FS  +       F L+  TG++T+L  LDFE    Y   + ARDGG
Sbjct: 267 TDQDEGVNAEITFSFSEASQI---TQFDLNSNTGEITVLNTLDFEEVKEYSIVLEARDGG 323

Query: 327 SPAMEQHCSLRVDLLDVNDNAPYITVTSELGTLPESAEPGTVVALISVQDPDSGSNGDVS 386
              M   C++ V+++D NDNAP +   S    + E AE GT +AL+ V+D DS  NG+V+
Sbjct: 324 G--MIAQCTVEVEVIDENDNAPEVIFQSLPNLIMEDAELGTHIALLKVRDKDSRHNGEVT 381

Query: 387 LRIPDHLPFALKSAFRNQFSLVTAGPLDREAKSSYDIMVTASDAGNPPLSTHRTIFLNIS 446
            ++   +PF + ++ RN + LVT   LDRE    Y+I VTA+D G PPLS+  +I L+I 
Sbjct: 382 CKLEGDVPFKILTSSRNTYKLVTDAVLDREQNPEYNITVTATDRGKPPLSSSSSITLHIG 441

Query: 447 DVNDNPPSFFQRSHEVFVPENNRPGDLLCSLAASDPDSGLNALISYSLLEPRNRDVSASS 506
           DVNDN P F Q S+ V V ENN PG  +  + ASDPD G N  +SY ++         SS
Sbjct: 442 DVNDNAPVFSQSSYIVHVAENNPPGASISQVRASDPDLGPNGQVSYCIMASDLEQRELSS 501

Query: 507 FISLNPQTGAVHATRSFDYEQTQTLQFEVQARDRGNPPLSSTVTVRLFVLDLNDNAPAVL 566
           ++S++ ++G V A R+FD+EQ +  +  +QARD+G+P LS+ V++R+ V D NDNAP VL
Sbjct: 502 YVSISAESGVVFAQRAFDHEQLRAFELTLQARDQGSPALSANVSLRVLVDDRNDNAPRVL 561

Query: 567 RPRARP-GSLCPQALPPSVGAGHLITKVTAVDLDSGYNAWVSYQLLEAPDPSLFAVSRYA 625
            P   P GS     +P +   G+L+TKV AVD DSG+NAW+SY +L+A +P LF++    
Sbjct: 562 YPALGPDGSALFDMVPHAAEPGYLVTKVVAVDADSGHNAWLSYHVLQASEPGLFSLGLRT 621

Query: 626 GEVRTAVPI-PADLPPQKLVIVVKDSGSPPLSTSVTLLVSLEEDTHPVVPDLRESSAPRE 684
           GEVRTA  +   D   Q+L++ V+D G PPLS + TL +   +    V+PD+ +   P +
Sbjct: 622 GEVRTARALGDRDAVRQRLLVAVRDGGQPPLSATATLHLVFADSLQEVLPDITDRPDPSD 681

Query: 685 GESRLTLYLAVSLVAICFVSFGSFVALLSKCLRGAACGVT--CFPAGTCACLTRSRRREG 742
            ++ L  YL V+L  I  +   + +  ++  LR ++   +  CF  G C       + E 
Sbjct: 682 LQAELQFYLVVALALISVLFLVAMILAIALRLRRSSSPASWSCFQPGLCV------KSES 735

Query: 743 LPPSNGILRIQLGSDDPIKFVDVGGHSHGCTP----LASAPTRSDSFMMVKSPSAPMAGE 798
           + P N                    +S G  P    L  A T    F  +K      +G+
Sbjct: 736 VVPPN--------------------YSEGTLPYSYNLCVAHTGKTEFNFLKCSEQLSSGQ 775

Query: 799 PVR---------PSCPPSDLLYGLEQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQF 849
            +          P C  S+L    +QAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQF
Sbjct: 776 DILCGDSSGALFPLCNSSELT-SHQQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQF 834

Query: 850 DTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNAT 909
           DTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNAT
Sbjct: 835 DTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNAT 894

Query: 910 LTNAAGKRDGKAPAGGNGNKKKSGKKEKK 938
           LTNAAGKRDGKAPAGGNGNKKKSGKKEKK
Sbjct: 895 LTNAAGKRDGKAPAGGNGNKKKSGKKEKK 923


>gi|11128041 protocadherin gamma subfamily A, 10 isoform 1 precursor
           [Homo sapiens]
          Length = 936

 Score =  805 bits (2078), Expect = 0.0
 Identities = 460/943 (48%), Positives = 594/943 (62%), Gaps = 46/943 (4%)

Query: 17  LLFLFYHLGYVCG--QIRYPVPEESQEGTFVGNVAQDFLLDTDSLSARRLQVAGEVNQRH 74
           LL LF+ + +  G  QI Y +PEE ++G+FVGN+++D  L    L+ R +++      + 
Sbjct: 19  LLCLFFGIPWEAGARQISYSIPEELEKGSFVGNISKDLGLAPRELAERGVRIVSRGRTQL 78

Query: 75  FRVDLDSGALLIKNPIDREALCGLSASCIVPLEFVTEGPLEMYRAEVEIVDVNDHAPRFP 134
           F ++  SG+L+    IDRE LC  SA C+V    + E  ++++  E+E+ D+ND+AP+F 
Sbjct: 79  FSLNPRSGSLITAGRIDREELCAQSARCVVSFNILVEDRVKLFGIEIEVTDINDNAPKFQ 138

Query: 135 RQQLDLEIGEAAPPGQRFPLEKAQDADVGSNSISSYRLSSNEHFALDVKKRSDGSLVPEL 194
            + LD++I E    G RFPL +A D DVG NS+ SY+LS N+HF+L V+ R++G   PEL
Sbjct: 139 AENLDVKINENVAAGMRFPLPEAIDPDVGVNSLQSYQLSPNKHFSLRVQSRANGVKYPEL 198

Query: 195 LLEKPLDREKQSDYRLVLTAVDGGNPPRSGTAELRVSVLDVNDNAPAFQQSSYRISVLES 254
           +LE  LDRE+++ + LVLTA DGG+P RSGT  + V+V D NDNAP F    YR+SV E+
Sbjct: 199 VLEHSLDREEEAIHHLVLTASDGGDPLRSGTVLVSVTVFDANDNAPVFTLPEYRVSVPEN 258

Query: 255 APAGMVLIQLNASDPDLGPSGNVTFYFSGHTPDRVRNLFSLHPTTGKLTLLGPLDFESEN 314
            P G  L+ + A+D D G +G VT+ F    PD     F L+  TG++ +   LD+E   
Sbjct: 259 LPVGTQLLTVTATDRDEGANGEVTYSFR-KLPDTQLLKFQLNKYTGEIKISENLDYEETG 317

Query: 315 YYEFDVRARDGGSPAMEQHCSLRVDLLDVNDNAPYITVTSELGTLPESAEPGTVVALISV 374
           +YE +++A DGG+        + V+  DVNDN+P +T+TS    + E +  GTVVAL++V
Sbjct: 318 FYEIEIQAEDGGAYLATAKVLITVE--DVNDNSPELTITSLFSPVTEDSPLGTVVALLNV 375

Query: 375 QDPDSGSNGDVSLRIPDHLPFALKSAFRNQFSLVTAGPLDREAKSSYDIMVTASDAGNPP 434
            D DS  NG V+  I  +LPF L+ +  + + LV    LDRE  SSY+I VTA+D G+PP
Sbjct: 376 HDLDSEQNGQVTCSILAYLPFKLEKSIDSYYRLVIHRALDREQVSSYNITVTATDGGSPP 435

Query: 435 LSTHRTIFLNISDVNDNPPSFFQRSHEVFVPENNRPGDLLCSLAASDPDSGLNALISYSL 494
           LST     L ++D+NDNPP+F Q S+  ++PENN  G  + S+ A DPDS  NA I YSL
Sbjct: 436 LSTEAHFMLQVADINDNPPTFSQVSYFTYIPENNARGASIFSVTALDPDSKENAQIIYSL 495

Query: 495 LEPRNRDVSASSFISLNPQTGAVHATRSFDYEQTQTLQFEVQARDRGNPPLSSTVTVRLF 554
            E   + V  SS+IS+N  TG ++A RSFDYEQ   LQ +V A D G+PPLSS V++ LF
Sbjct: 496 AEDTIQGVPLSSYISINSDTGVLYALRSFDYEQFHELQMQVTASDSGDPPLSSNVSLSLF 555

Query: 555 VLDLNDNAPAVLRPR-ARPGSLCPQALPPSVGAGHLITKVTAVDLDSGYNAWVSYQLLEA 613
           VLD NDNAP +L P     GS   +  P S   G+L+TKV AVD DSG NAW+SY+LL+A
Sbjct: 556 VLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSYRLLKA 615

Query: 614 PDPSLFAVSRYAGEVRTA-VPIPADLPPQKLVIVVKDSGSPPLSTSVTLLVSLEEDTHPV 672
            +P LFAV  + GEVRTA   +  D   Q LV+ V+D G PPLS +VTL V++ +    V
Sbjct: 616 SEPGLFAVGEHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADSIPQV 675

Query: 673 VPDLRESSAPREGE-SRLTLYLAVSLVAICFVSFGSFVALLSKCLRGAACGVTCFPAGTC 731
           + DL    +P   E S LTLYL V++ A+  V     + LL+  LR              
Sbjct: 676 LADLGSFESPANSETSDLTLYLVVAVAAVSCVFLAFVIVLLAHRLR-------------- 721

Query: 732 ACLTRSRRREGLPPSNGILRIQLGSDDPIKFVDVGG-------HSHGCTPLASAPTRSDS 784
               R  +   L  S G L    GS     FV V G       +SH  +  A +      
Sbjct: 722 ----RWHKSRLLQASGGGLTGVSGS----HFVGVDGVRAFLQTYSHEVSLTADSRKSHLI 773

Query: 785 FMMVKSPSAPMAGEPVRPSCPPS---DLLYGLE------QAPPNTDWRFSQAQRPGTSGS 835
           F         ++ E    + P S   D  + +E      QAPPNTDWRFSQAQRPGTSGS
Sbjct: 774 FPQPNYADTLISQESCEKNDPLSLLDDSKFPIEDTPLVPQAPPNTDWRFSQAQRPGTSGS 833

Query: 836 QNGDDTGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVP 895
           QNGDDTGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVP
Sbjct: 834 QNGDDTGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVP 893

Query: 896 DYRQNVYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK 938
           DYRQNVYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK
Sbjct: 894 DYRQNVYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK 936


>gi|11128027 protocadherin gamma subfamily B, 7 isoform 1 precursor
           [Homo sapiens]
          Length = 929

 Score =  805 bits (2078), Expect = 0.0
 Identities = 439/926 (47%), Positives = 592/926 (63%), Gaps = 21/926 (2%)

Query: 17  LLFLFYHLGYVCGQIRYPVPEESQEGTFVGNVAQDFLLDTDSLSARRLQVAGEVNQRHFR 76
           LL LFY    +C  IRY +PEE  +G+ VGN+A+D  L    +SAR L+V+ E  + HF 
Sbjct: 21  LLPLFYPT--LCEPIRYSIPEELAKGSVVGNLAKDLGLSVLDVSARELRVSAE--KLHFS 76

Query: 77  VDLDSGALLIKNPIDREALCGLSASCIVPLEFVTEGPLEMYRAEVEIVDVNDHAPRFPRQ 136
           VD  SG LL+K+ IDRE +C     C + LE V E PL ++   V I DVNDHAP+F + 
Sbjct: 77  VDAQSGDLLVKDRIDREQICKERRRCELQLEAVVENPLNIFHVIVVIEDVNDHAPQFRKD 136

Query: 137 QLDLEIGEAAPPGQRFPLEKAQDADVGSNSISSYRLSSNEHFALDVKKRSDGSLVPELLL 196
           +++LEI E+   G    LE A+D D+  NS+S Y+LS NE+F+L  K   DG   PEL+L
Sbjct: 137 EINLEISESVSLGMGTILESAEDPDISMNSLSKYQLSPNEYFSLVEKDNPDGGKYPELVL 196

Query: 197 EKPLDREKQSDYRLVLTAVDGGNPPRSGTAELRVSVLDVNDNAPAFQQSSYRISVLESAP 256
           +K LDRE QS + LVLTA+DGG+PPRSGTA++R+ V+D NDN P F Q  YR+S+ E  P
Sbjct: 197 QKTLDRETQSAHHLVLTALDGGDPPRSGTAQIRILVIDANDNPPVFSQDVYRVSLREDVP 256

Query: 257 AGMVLIQLNASDPDLGPSGNVTFYFSGHTPDRVRNLFSLHPTTGKLTLLGPLDFESENYY 316
            G  ++++ A+D D G +  +T+ F G   D+ +++FSL  TTG +    PLDFE    Y
Sbjct: 257 PGTSILRVKATDQDEGINSEITYSFFG-VADKAQHVFSLDYTTGNILTQQPLDFEEVERY 315

Query: 317 EFDVRARDGGSPAMEQHCSLRVDLLDVNDNAPYITVTSELGTLPESAEPGTVVALISVQD 376
             ++ A+D GS  +   C + V+++D NDN+P I +TS    + E + PG VVAL   +D
Sbjct: 316 TINIEAKDRGS--LSTRCKVIVEVVDENDNSPEIIITSLSDQIMEDSPPGVVVALFKTRD 373

Query: 377 PDSGSNGDVSLRIPDHLPFALKSAFRNQFSLVTAGPLDREAKSSYDIMVTASDAGNPPLS 436
            DSG NG+V   +   +PF + S+  N + LVT   LDRE    Y++ + A+D G PPLS
Sbjct: 374 QDSGENGEVRCSLSRGVPFKIHSSSNNYYKLVTDEALDREQTPEYNVTIAATDRGKPPLS 433

Query: 437 THRTIFLNISDVNDNPPSFFQRSHEVFVPENNRPGDLLCSLAASDPDSGLNALISYSLLE 496
           + +TI L+I+DVNDN P F Q ++ V VPENN+PG  +  ++ASDPD GLN  +SYSL+ 
Sbjct: 434 SSKTITLHITDVNDNAPVFGQSAYLVHVPENNQPGASIAQVSASDPDFGLNGRVSYSLIA 493

Query: 497 PRNRDVSASSFISLNPQTGAVHATRSFDYEQTQTLQFEVQARDRGNPPLSSTVTVRLFVL 556
                 + SS++S++ Q+G V A R+FD+EQ +T +  +QARD+G+P LS+ V++R+ V 
Sbjct: 494 SDLESRTLSSYVSVSAQSGVVFAQRAFDHEQLRTFELTLQARDQGSPALSANVSLRVLVG 553

Query: 557 DLNDNAPAVLRPRARP-GSLCPQALPPSVGAGHLITKVTAVDLDSGYNAWVSYQLLEAPD 615
           D NDNAP VL P   P GS     +P +   G+L+TKV AVD DSG+NAW+SY +++A +
Sbjct: 554 DRNDNAPRVLYPALGPDGSALFDTVPRAAQPGYLVTKVVAVDADSGHNAWLSYHVVQASE 613

Query: 616 PSLFAVSRYAGEVRTAVPI-PADLPPQKLVIVVKDSGSPPLSTSVTLLVSLEEDTHPVVP 674
           P LF++    GEVR    +   D   Q+L++ V+D G PPLS + TL +   +    V+P
Sbjct: 614 PGLFSLGLRTGEVRMVRALGDKDSVRQRLLVAVRDGGQPPLSATATLHLVFADSLQEVLP 673

Query: 675 DLRESSAPREGESRLTLYLAVSLVAICFVSFGSFVALLSKCLRGAACGVT--CFPAGTCA 732
           D  +   P + ++ +  YL V+L  I  +   + +  ++  LR +       CF +  C 
Sbjct: 674 DFSDHPTPSDSQAEMQFYLVVALALISVLFLLAVILAIALRLRQSFSPTAGDCFESVLC- 732

Query: 733 CLTRSRRREGLPPSNGILRIQLGSDDPIKFVDVGGHSHGCTPLASAPTRSDSFMMVKSPS 792
               S+     PP+     +    +  +    +    +  T +   P   D+     +  
Sbjct: 733 ----SKSGPVGPPNYSEGTLPYAYNFCVPGDQMNPEFNFFTSVDHCPATQDNL----NKD 784

Query: 793 APMAGEPVRPSCPPSDLLYGLEQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQFDTE 852
           + +    + PS   +D     +QAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQFDTE
Sbjct: 785 SMLLASILTPSV-EADKKILKQQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQFDTE 843

Query: 853 MLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATLTN 912
           MLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATLTN
Sbjct: 844 MLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATLTN 903

Query: 913 AAGKRDGKAPAGGNGNKKKSGKKEKK 938
           AAGKRDGKAPAGGNGNKKKSGKKEKK
Sbjct: 904 AAGKRDGKAPAGGNGNKKKSGKKEKK 929


>gi|8850232 protocadherin gamma subfamily A, 12 isoform 1 precursor
           [Homo sapiens]
          Length = 932

 Score =  803 bits (2074), Expect = 0.0
 Identities = 456/935 (48%), Positives = 594/935 (63%), Gaps = 54/935 (5%)

Query: 28  CGQIRYPVPEESQEGTFVGNVAQDFLLDTDSLSARRLQVAGEVNQRHFRVDLDSGALLIK 87
           C QIRY VPEE ++G+ VG++++D  L+   L+ R +++      + F ++  SG+L+  
Sbjct: 28  CTQIRYSVPEELEKGSRVGDISRDLGLEPRELAERGVRIIPRGRTQLFALNPRSGSLVTA 87

Query: 88  NPIDREALCGLSASCIVPLEFVTEGPLEMYRAEVEIVDVNDHAPRFPRQQLDLEIGEAAP 147
             IDRE LC  +  C + L+ + E  +++Y  EVE+ D+ND+AP F   +L+++I E A 
Sbjct: 88  GRIDREELCMGAIKCQLNLDILMEDKVKIYGVEVEVRDINDNAPYFRESELEIKISENAA 147

Query: 148 PGQRFPLEKAQDADVGSNSISSYRLSSNEHFALDVKKRSDGSLVPELLLEKPLDREKQSD 207
              RFPL  A D D+G NS+ SY LS N HF+L V+  +DGS  PEL+L++ LDRE+++ 
Sbjct: 148 TEMRFPLPHAWDPDIGKNSLQSYELSPNTHFSLIVQNGADGSKYPELVLKRALDREEKAA 207

Query: 208 YRLVLTAVDGGNPPRSGTAELRVSVLDVNDNAPAFQQSSYRISVLESAPAGMVLIQLNAS 267
           + LVLTA DGG+P R+GTA +RV VLD NDNAPAF Q  YR SV E+   G  L+ +NA+
Sbjct: 208 HHLVLTASDGGDPVRTGTARIRVMVLDANDNAPAFAQPEYRASVPENLALGTQLLVVNAT 267

Query: 268 DPDLGPSGNVTFYFSGHTPDRVRNLFSLHPTTGKLTLLGPLDFESENYYEFDVRARDGGS 327
           DPD G +  V + F  +  D+   +F L   +G ++ +G LD E   +Y+ +V+A D   
Sbjct: 268 DPDEGVNAEVRYSFR-YVDDKAAQVFKLDCNSGTISTIGELDHEESGFYQMEVQAMDNAG 326

Query: 328 PAMEQHCSLRVDLLDVNDNAPYITVTSELGTLPESAEPGTVVALISVQDPDSGSNGDVSL 387
                   + + +LDVNDNAP + +TS   ++PE++  GT++AL++V D DS  NG V  
Sbjct: 327 --YSARAKVLITVLDVNDNAPEVVLTSLASSVPENSPRGTLIALLNVNDQDSEENGQVIC 384

Query: 388 RIPDHLPFALKSAFRNQFSLVTAGPLDREAKSSYDIMVTASDAGNPPLSTHRTIFLNISD 447
            I  +LPF L+ ++ N +SLVT   LDRE   SY+I VTA+D G PPLST   I LN++D
Sbjct: 385 FIQGNLPFKLEKSYGNYYSLVTDIVLDREQVPSYNITVTATDRGTPPLSTETHISLNVAD 444

Query: 448 VNDNPPSFFQRSHEVFVPENNRPGDLLCSLAASDPDSGLNALISYSLLEPRNRDVSASSF 507
            NDNPP F Q S+  ++PENN  G  L S+ A DPD   NA I+YSL E   +  S SS+
Sbjct: 445 TNDNPPVFPQASYSAYIPENNPRGVSLVSVTAHDPDCEENAQITYSLAENTIQGASLSSY 504

Query: 508 ISLNPQTGAVHATRSFDYEQTQTLQFEVQARDRGNPPLSSTVTVRLFVLDLNDNAPAVLR 567
           +S+N  TG ++A  SFDYEQ + LQ +V ARD G+PPLSS V++ LFVLD NDNAP +L 
Sbjct: 505 VSINSDTGVLYALSSFDYEQFRDLQVKVMARDNGHPPLSSNVSLSLFVLDQNDNAPEILY 564

Query: 568 PR-ARPGSLCPQALPPSVGAGHLITKVTAVDLDSGYNAWVSYQLLEAPDPSLFAVSRYAG 626
           P     GS   +  P S   G+L+TKV AVD DSG NAW+SY+LL+A +P LF+V  + G
Sbjct: 565 PALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSYRLLKASEPGLFSVGLHTG 624

Query: 627 EVRTA-VPIPADLPPQKLVIVVKDSGSPPLSTSVTLLVSLEEDTHPVVPDLRESSAPREG 685
           EVRTA   +  D   Q LV+ V+D G PPLS +VTL V++ +    V+ DL    +P   
Sbjct: 625 EVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADSIPQVLADLGSLESPANS 684

Query: 686 E-SRLTLYLAVSLVAICFVSFGSFVALL----------SKCLRGAACGVTCFPAGTCACL 734
           E S LTLYL V++ A+  V F +FV LL          S+ L+ +  G+T          
Sbjct: 685 ETSDLTLYLVVAVAAVSCV-FLAFVILLLALRLRRWHKSRLLQASGGGLT---------- 733

Query: 735 TRSRRREGLPPSNGILRIQLGSDDPIKFVDVGGHSHGCTPLASA-----PTRSDSFMMVK 789
                  G P S+ +     G D    F+    H    T  +       P  + + M+V 
Sbjct: 734 -------GAPASHFV-----GVDGVQAFLQTYSHEVSLTTDSRKSHLIFPQPNYADMLVS 781

Query: 790 SPSAPMAGEPVRPSCPPSDLLYG------LEQAPPNTDWRFSQAQRPGTSGSQNGDDTGT 843
             S     E   P     D ++       +EQAPPNTDWRFSQAQRPGTSGSQNGDDTGT
Sbjct: 782 QESF----EKSEPLLLSGDSVFSKDSHGLIEQAPPNTDWRFSQAQRPGTSGSQNGDDTGT 837

Query: 844 WPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYI 903
           WPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYI
Sbjct: 838 WPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYI 897

Query: 904 PGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK 938
           PGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK
Sbjct: 898 PGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK 932


>gi|11128035 protocadherin gamma subfamily B, 2 isoform 1 precursor
           [Homo sapiens]
          Length = 931

 Score =  803 bits (2073), Expect = 0.0
 Identities = 441/939 (46%), Positives = 604/939 (64%), Gaps = 32/939 (3%)

Query: 13  RWATLLFLFY---HLGYVCGQIRYPVPEESQEGTFVGNVAQDFLLDTDSLSARRLQVAGE 69
           RW  +L  F      G +  QIRY +PEE  + + VGN+A+D  L    L AR+L+V+ E
Sbjct: 12  RWLQVLLPFLLSLFPGALPVQIRYSIPEELAKNSVVGNLAKDLGLSVRDLPARKLRVSAE 71

Query: 70  VNQRHFRVDLDSGALLIKNPIDREALCGLSASCIVPLEFVTEGPLEMYRAEVEIVDVNDH 129
             + +F V+ +SG LL+ + IDRE +CG    C++  + V E PL ++   V + D+ND+
Sbjct: 72  --KEYFTVNPESGDLLVSDRIDREQICGKQPLCVLDFDTVAENPLNIFYIAVIVQDINDN 129

Query: 130 APRFPRQQLDLEIGEAAPPGQRFPLEKAQDADVGSNSISSYRLSSNEHFALDVKKRSDGS 189
            P F + +++L+IGE+  PG  FPL+ A D+DVG NS+  Y L+ NE+F L  K+  DG 
Sbjct: 130 TPLFKQTKINLKIGESTKPGTTFPLDPALDSDVGPNSLQRYHLNDNEYFDLAEKQTPDGR 189

Query: 190 LVPELLLEKPLDREKQSDYRLVLTAVDGGNPPRSGTAELRVSVLDVNDNAPAFQQSSYRI 249
             PEL+L+  LDRE+ S ++LVLTAVDGG+PP+SGT ++R+ V D NDN P F Q  YR+
Sbjct: 190 KYPELILKHSLDREEHSLHQLVLTAVDGGDPPQSGTTQIRIKVTDANDNPPVFSQDVYRV 249

Query: 250 SVLESAPAGMVLIQLNASDPDLGPSGNVTFYFSGHTPDRVRNLFSLHPTTGKLTLLGPLD 309
           ++ E  P G  ++Q+ A+D D G +  +T+ F  +  ++V++ F+L+  TG++T    LD
Sbjct: 250 TLREDVPPGFFVLQVTATDRDEGINAEITYSFH-NVDEQVKHFFNLNEKTGEITTKDDLD 308

Query: 310 FESENYYEFDVRARDGGSPAMEQHCSLRVDLLDVNDNAPYITVTSELGTLPESAEPGTVV 369
           FE  + Y   + A+D G  A   HCS++V++LD ND AP + VTS    LPE + PGTV+
Sbjct: 309 FEIASSYTLSIEAKDPGDLAA--HCSIQVEILDDNDCAPEVIVTSVSTPLPEDSPPGTVI 366

Query: 370 ALISVQDPDSGSNGDVSLRIPDHLPFALKSAFRNQFSLVTAGPLDREAKSSYDIMVTASD 429
           ALI  +D DSG NG+V  ++  +  F LKS+ +N + LVT G LDRE    Y++ +TA+D
Sbjct: 367 ALIKTRDRDSGENGEVYCQVLGNAKFILKSSSKNYYKLVTDGALDREEIPEYNLTITATD 426

Query: 430 AGNPPLSTHRTIFLNISDVNDNPPSFFQRSHEVFVPENNRPGDLLCSLAASDPDSGLNAL 489
            G PPLS+   + L+ISDVNDN P F Q S+ V V ENN PG  +  ++ASDPD G +  
Sbjct: 427 GGKPPLSSSIIVTLHISDVNDNAPVFQQTSYMVHVAENNPPGASIAQISASDPDLGPSGQ 486

Query: 490 ISYSLLEPRNRDVSASSFISLNPQTGAVHATRSFDYEQTQTLQFEVQARDRGNPPLSSTV 549
           +SYS++    +     S++S++ Q+G V A R+FD+EQ +  +  +QARD+G+P LS+ V
Sbjct: 487 VSYSIVASDLKPREILSYVSVSAQSGVVFAQRAFDHEQLRAFELTLQARDQGSPALSANV 546

Query: 550 TVRLFVLDLNDNAPAVLRPRARP-GSLCPQALPPSVGAGHLITKVTAVDLDSGYNAWVSY 608
           ++R+ V DLNDNAP VL P   P GS     +P +   G+L+TKV AVD DSG+NAW+SY
Sbjct: 547 SLRVLVGDLNDNAPRVLYPALGPDGSALFDMVPRAAEPGYLVTKVVAVDADSGHNAWLSY 606

Query: 609 QLLEAPDPSLFAVSRYAGEVRTAVPI-PADLPPQKLVIVVKDSGSPPLSTSVTLLVSLEE 667
            +L+A +P LF++    GEVRTA  +   D   Q+L++ V+D G PPLS + TL +   +
Sbjct: 607 HVLQASEPGLFSLGLRTGEVRTARALGDRDAARQRLLVAVRDGGQPPLSATATLHLIFAD 666

Query: 668 DTHPVVPDLRESSAPREGESRLTLYLAVSLVAICFVSFGSFVALLSKCLR--GAACGVTC 725
               V+PDL +   P + +++L  YL V+L  I  + F + +  +S  LR    +    C
Sbjct: 667 SLQEVLPDLSDRREPSDPQAKLQFYLVVALALISVLFFLAVILAISLRLRLSSRSDAWDC 726

Query: 726 FPAGTCA----CLTRSRRREGLPPSNGILRIQLGSDDPIKFVDVGGHSHGCTP--LASAP 779
           F  G  +     +  +     LP S  +      +     F+++       TP  + +  
Sbjct: 727 FQPGLSSKPGPGVLPNYSEGTLPYSYNLCVASQSAKTEFNFLNI-------TPELVPAQD 779

Query: 780 TRSDSFMMVKSPSAPMAGEPVRPSCPPSDLLYGLEQAPPNTDWRFSQAQRPGTSGSQNGD 839
              D+    ++ +   AG P       SD +  L+QAPPNTDWRFSQAQRPGTSGSQNGD
Sbjct: 780 LVCDNASWEQNTNHGAAGVPF-----ASDTI--LKQAPPNTDWRFSQAQRPGTSGSQNGD 832

Query: 840 DTGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQ 899
           DTGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQ
Sbjct: 833 DTGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQ 892

Query: 900 NVYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK 938
           NVYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK
Sbjct: 893 NVYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK 931


>gi|11128029 protocadherin gamma subfamily B, 6 isoform 1 precursor
           [Homo sapiens]
          Length = 930

 Score =  801 bits (2069), Expect = 0.0
 Identities = 448/933 (48%), Positives = 588/933 (63%), Gaps = 34/933 (3%)

Query: 17  LLFLFYHLGYVCGQIRYPVPEESQEGTFVGNVAQDFLLDTDSLSARRLQVAGEVNQRHFR 76
           LL LFY    +   IRY +PEE  +G+ VGN+A+D  L    +SAR+L+V+ E  + HF 
Sbjct: 21  LLPLFYPT--LSEPIRYSIPEELAKGSVVGNLAKDLGLSVLDVSARKLRVSAE--KLHFS 76

Query: 77  VDLDSGALLIKNPIDREALCGLSASCIVPLEFVTEGPLEMYRAEVEIVDVNDHAPRFPRQ 136
           VD +SG LL+KN IDRE +C     C + LE V E PL ++   V I DVNDHAP+F ++
Sbjct: 77  VDAESGDLLVKNRIDREQICKERRRCELQLEAVVENPLNIFHVIVVIEDVNDHAPQFDKK 136

Query: 137 QLDLEIGEAAPPGQRFPLEKAQDADVGSNSISSYRLSSNEHFALDVKKRSDGSLVPELLL 196
           ++ LEI E+A  G R  L+ A D D+  NSI  Y+++SN +F+L V+  SDG   PEL L
Sbjct: 137 EIHLEIFESASAGTRLSLDPATDPDININSIKDYKINSNPYFSLMVRVNSDGGKYPELSL 196

Query: 197 EKPLDREKQSDYRLVLTAVDGGNPPRSGTAELRVSVLDVNDNAPAFQQSSYRISVLESAP 256
           EK LDRE+Q  + L+LTA+DGG+PPRS TA + +SV D NDN P F +  YRIS+ E+ P
Sbjct: 197 EKLLDREEQRSHSLILTALDGGDPPRSATAHIEISVKDTNDNPPVFSRDEYRISLSENLP 256

Query: 257 AGMVLIQLNASDPDLGPSGNVTFYFSGHTPDRVRNLFSLHPTTGKLTLLGPLDFESENYY 316
            G  ++Q+ A+D D G +  + +YF   T    +++FSL   TG +      DFE    Y
Sbjct: 257 PGSPVLQVTATDQDEGVNAEINYYFRS-TAQSTKHMFSLDEKTGMIKNNQSFDFEDVERY 315

Query: 317 EFDVRARDGGSPAMEQHCSLRVDLLDVNDNAPYITVTSELGTLPESAEPGTVVALISVQD 376
             +V A+DGG   +   C + +++LD NDN+P I +TS    + E++ PG VVAL   +D
Sbjct: 316 TMEVEAKDGGG--LSTQCKVIIEILDENDNSPEIIITSLSDQILENSPPGMVVALFKTRD 373

Query: 377 PDSGSNGDVSLRIPDHLPFALKSAFRNQFSLVTAGPLDREAKSSYDIMVTASDAGNPPLS 436
            D G NG+V   I   +PF + S+  N + LVT G LDRE    Y++ + A+D G PPLS
Sbjct: 374 LDFGGNGEVRCNIETDIPFKIYSSSNNYYKLVTDGALDREQTPEYNVTIVATDRGKPPLS 433

Query: 437 THRTIFLNISDVNDNPPSFFQRSHEVFVPENNRPGDLLCSLAASDPDSGLNALISYSLLE 496
           + R+I L ++D+NDN P F Q S+ V V ENN PG  +  ++ASDPD GLN  ISYS++ 
Sbjct: 434 SSRSITLYVADINDNAPVFDQTSYVVHVAENNPPGASIAQVSASDPDLGLNGHISYSIVA 493

Query: 497 PRNRDVSASSFISLNPQTGAVHATRSFDYEQTQTLQFEVQARDRGNPPLSSTVTVRLFVL 556
                ++ SS++S++ Q+G V A R+FD+EQ +     +QARD G+P LS+ V++R+ V 
Sbjct: 494 SDLEPLAVSSYVSVSAQSGVVFAQRAFDHEQLRAFALTLQARDHGSPTLSANVSLRVLVG 553

Query: 557 DLNDNAPAVLRPRARP-GSLCPQALPPSVGAGHLITKVTAVDLDSGYNAWVSYQLLEAPD 615
           D NDNAP VL P   P GS     +P S   G+L+TKV AVD DSG+NAW+SY +L+A +
Sbjct: 554 DRNDNAPRVLYPALGPDGSAFFDMVPRSAEPGYLVTKVVAVDADSGHNAWLSYHVLQASE 613

Query: 616 PSLFAVSRYAGEVRTAVPI-PADLPPQKLVIVVKDSGSPPLSTSVTLLVSLEEDTHPVVP 674
           P LF++    GEVRTA  +   D   Q+L++ V+D G PPLS + TL +   ++   ++P
Sbjct: 614 PGLFSLGLRTGEVRTARALGDRDAARQRLLVAVRDGGQPPLSATATLHLVFADNLQEILP 673

Query: 675 DLRESSAPREGESRLTLYLAVSLVAICFVSFGSFVALLSKCLRGAACGVT--CFPAGTCA 732
           DL +     + ++ L  YL V+L  I  +   + +  ++  LR +    T  CF  G C 
Sbjct: 674 DLSDRPVLSDPQAELQFYLVVALALISVLFLLAVILAIALRLRRSLSPATWDCFHPGLCV 733

Query: 733 C---LTRSRRREGLPPSNGILRIQLGSDDPIKFVDVGGHSHGCTPLASAPTRSDSFMMVK 789
               +      EG  P +  L I         F+             S P  S+  M+  
Sbjct: 734 KSGPVVPPNYSEGTLPYSYNLCIAHTGTKEFNFLK-----------CSVPLHSNEDMVCS 782

Query: 790 -SPSA---PMAGEPVRPSCPPSDLLYGLEQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWP 845
            SP A   P  GE +  +  P  L     QAPPNTDWRFSQAQRPGTSGSQNGDDTGTWP
Sbjct: 783 VSPGALIPPHGGEDL--TSHPETLT---SQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWP 837

Query: 846 NNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPG 905
           NNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPG
Sbjct: 838 NNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPG 897

Query: 906 SNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK 938
           SNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK
Sbjct: 898 SNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK 930


>gi|11056030 protocadherin gamma subfamily A, 2 isoform 1 precursor
           [Homo sapiens]
          Length = 932

 Score =  801 bits (2068), Expect = 0.0
 Identities = 450/934 (48%), Positives = 583/934 (62%), Gaps = 54/934 (5%)

Query: 29  GQIRYPVPEESQEGTFVGNVAQDFLLDTDSLSARRLQVAGEVNQRHFRVDLDSGALLIKN 88
           GQIRY V EE   G+FVGN+A+D  L+  +L+ + +++      + F ++  SG+L+  N
Sbjct: 29  GQIRYSVREEIDRGSFVGNIAKDLGLEPLALAEQGVRIVSRGRSQLFALNPRSGSLVTAN 88

Query: 89  PIDREALCGLSASCIVPLEFVTEGPLEMYRAEVEIVDVNDHAPRFPRQQLDLEIGEAAPP 148
            IDRE LC  SA C++    + E  L +Y  EVEI D+ND+APRF  ++L+L+I E   P
Sbjct: 89  RIDREELCAQSAPCLLNFNILLEDKLTIYSVEVEITDINDNAPRFGVEELELKISETTTP 148

Query: 149 GQRFPLEKAQDADVGSNSISSYRLSSNEHFALDVKKRSDGSLVPELLLEKPLDREKQSDY 208
           G R PL+ A DADVG N++  Y L+ N+HF+LDV++ +DG+  PEL+LE+ LDRE+++ +
Sbjct: 149 GFRIPLKNAHDADVGENALQKYALNPNDHFSLDVRRGADGNKYPELVLERSLDREEEAVH 208

Query: 209 RLVLTAVDGGNPPRSGTAELRVSVLDVNDNAPAFQQSSYRISVLESAPAGMVLIQLNASD 268
            LVL A DGG+P  SGT+ + V VLD NDNAP F Q  YRIS+ E+   G  ++ + A+D
Sbjct: 209 HLVLVASDGGDPVLSGTSRICVKVLDANDNAPVFTQPEYRISIPENTLVGTRILTVTATD 268

Query: 269 PDLGPSGNVTFYFSGHTPDRVRNLFSLHPTTGKLTLLGPLDFESENYYEFDVRARDGGSP 328
            D G    V  YF   +P     +F L  T+G+LT++  LD+E   ++E D+ A+DG  P
Sbjct: 269 ADEGYYAQVV-YFLEKSPGETSEVFELKSTSGELTIIKDLDYEDATFHEIDIEAQDG--P 325

Query: 329 AMEQHCSLRVDLLDVNDNAPYITVTSELGTLPESAEPGTVVALISVQDPDSGSNGDVSLR 388
            +     + V +LDVNDNAP   +TS   ++ E + PGT++ L +V D DSG N   +  
Sbjct: 326 GLLTRAKVIVTVLDVNDNAPEFYMTSATSSVSEDSLPGTIIGLFNVHDRDSGQNAFTTCS 385

Query: 389 IPDHLPFALKSAFRNQFSLVTAGPLDREAKSSYDIMVTASDAGNPPLSTHRTIFLNISDV 448
           +P+ LPF L+ +  N + LVT   LDRE  S Y+I +TA D GNP LST   I L ++D+
Sbjct: 386 LPEDLPFKLEKSVDNYYRLVTTRALDREQFSFYNITLTAKDGGNPSLSTDAHILLQVADI 445

Query: 449 NDNPPSFFQRSHEVFVPENNRPGDLLCSLAASDPDSGLNALISYSLLEPRNRDVSASSFI 508
           NDN P+F + S+  ++PENN  G  + S+ A DPDS  NA ++YS  E   +    SS+I
Sbjct: 446 NDNAPAFSRTSYSTYIPENNPRGASVFSVTAHDPDSNDNAHVTYSFAEDTVQGAPLSSYI 505

Query: 509 SLNPQTGAVHATRSFDYEQTQTLQFEVQARDRGNPPLSSTVTVRLFVLDLNDNAPAVLRP 568
           S+N  TG ++A RSFDYEQ + LQ  V ARD GNPPLSS V++ LFVLD NDNAP +L P
Sbjct: 506 SINSDTGVLYALRSFDYEQLRDLQVWVIARDSGNPPLSSNVSLSLFVLDQNDNAPEILYP 565

Query: 569 R-ARPGSLCPQALPPSVGAGHLITKVTAVDLDSGYNAWVSYQLLEAPDPSLFAVSRYAGE 627
                GS   +  P S   G+L+TKV AVD DSG NAW+SY LL+A +P LF+V  + GE
Sbjct: 566 AFPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSYHLLKASEPGLFSVGLHTGE 625

Query: 628 VRTA-VPIPADLPPQKLVIVVKDSGSPPLSTSVTLLVSLEEDTHPVVPD---LRESSAPR 683
           VRTA   +  D   Q LV+ ++D G PPLS +VTL V++ +    ++ D   L  S+ P 
Sbjct: 626 VRTARALLDRDALKQSLVVAIQDHGQPPLSATVTLTVAVADRIPDILADLGSLEPSAIP- 684

Query: 684 EGESRLTLYLAVSLVAICFVSFGSFVALLSKCLRGAACGVTCFPAGTCACLTRSRRREGL 743
             +S LTLYL V++ A+  V     + LL+  LR                  R  +   L
Sbjct: 685 -NDSDLTLYLVVAVAAVSCVFLAFVIVLLAHRLR------------------RWHKSRLL 725

Query: 744 PPSNGILRIQ-----LGSDDPIKFVDVGGHSHGCTPLASAPTRSDSFMMVKSPSAPMAGE 798
             S G L        +G D    F+    H    T    A +R    +    P    A  
Sbjct: 726 QASGGSLTGMQSSHFVGVDGVRAFLQTYSHEVSLT----ADSRKSHLIF---PQPNYADT 778

Query: 799 PV-RPSCPPSDLLYG-------------LEQAPPNTDWRFSQAQRPGTSGSQNGDDTGTW 844
            + + SC   D L                +QAPPNTDWRFSQAQRPGTSGSQNGDDTGTW
Sbjct: 779 LISQESCEKKDFLSAPQSLLEEEREETFSQQAPPNTDWRFSQAQRPGTSGSQNGDDTGTW 838

Query: 845 PNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIP 904
           PNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIP
Sbjct: 839 PNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIP 898

Query: 905 GSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK 938
           GSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK
Sbjct: 899 GSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK 932


>gi|14270484 protocadherin gamma subfamily A, 8 isoform 1 precursor
           [Homo sapiens]
          Length = 932

 Score =  796 bits (2055), Expect = 0.0
 Identities = 445/919 (48%), Positives = 589/919 (64%), Gaps = 24/919 (2%)

Query: 29  GQIRYPVPEESQEGTFVGNVAQDFLLDTDSLSARRLQVAGEVNQRHFRVDLDSGALLIKN 88
           GQIRY VPEE+ +G+FVGN+++D  LD   L+   +++      + F ++  SG+L+   
Sbjct: 29  GQIRYSVPEETDKGSFVGNISKDLGLDPRKLAKHGVRIVSRGRTQLFALNPRSGSLITAG 88

Query: 89  PIDREALCGLSASCIVPLEFVTEGPLEMYRAEVEIVDVNDHAPRFPRQQLDLEIGEAAPP 148
            IDRE LC  S  C++ +  + E   +++  E+EI+D+ND+ P+F  + L+++I E A P
Sbjct: 89  RIDREELCAQSPRCLININTLVEDKGKLFGVEIEIIDINDNNPKFQVEDLEVKINEIAVP 148

Query: 149 GQRFPLEKAQDADVGSNSISSYRLSSNEHFALDVKKRSDGSLVPELLLEKPLDREKQSDY 208
           G R+PL +A D DVG NS+ SY+LS N HF+LDV+   +G++ PEL+LE+ LDRE+++ +
Sbjct: 149 GARYPLPEAVDPDVGVNSLQSYQLSPNHHFSLDVQTGDNGAINPELVLERALDREEEAAH 208

Query: 209 RLVLTAVDGGNPPRSGTAELRVSVLDVNDNAPAFQQSSYRISVLESAPAGMVLIQLNASD 268
            LVLTA DGG PPRS T  + V+VLD NDNAP F    YR+ VLE+ P G  L+ + ASD
Sbjct: 209 HLVLTASDGGKPPRSSTVRIHVTVLDTNDNAPVFPHPIYRVKVLENMPPGTRLLTVTASD 268

Query: 269 PDLGPSGNVTFYFSGHTPDRVRNLFSLHPTTGKLTLLGPLDFESENYYEFDVRARDGGSP 328
           PD G +G V + F     ++   LF L+  TG++++   LD+E  ++YE +++A D G  
Sbjct: 269 PDEGINGKVAYKFR-KINEKQTPLFQLNENTGEISIAKSLDYEECSFYEMEIQAEDVG-- 325

Query: 329 AMEQHCSLRVDLLDVNDNAPYITVTSELGTLPESAEPGTVVALISVQDPDSGSNGDVSLR 388
           A+     L + + DVNDN P + +TS    + E++ PGTV+A +SV D DSG NG V   
Sbjct: 326 ALLGRTKLLISVEDVNDNRPEVIITSLFSPVLENSLPGTVIAFLSVHDQDSGKNGQVVCY 385

Query: 389 IPDHLPFALKSAFRNQFSLVTAGPLDREAKSSYDIMVTASDAGNPPLSTHRTIFLNISDV 448
             D+LPF L+ +  N + LVT   LDRE  S Y+I V ASD G PPLST   I L+++D+
Sbjct: 386 TRDNLPFKLEKSIGNYYRLVTRKYLDRENVSIYNITVMASDLGTPPLSTETQIALHVADI 445

Query: 449 NDNPPSFFQRSHEVFVPENNRPGDLLCSLAASDPDSGLNALISYSLLEPRNRDVSASSFI 508
           NDNPP+F   S+  ++ ENN  G  + SL A DPDS  NA ++YS+ E   +    SS+I
Sbjct: 446 NDNPPTFPHASYSAYILENNLRGASIFSLTAHDPDSQENAQVTYSVTEDTLQGAPLSSYI 505

Query: 509 SLNPQTGAVHATRSFDYEQTQTLQFEVQARDRGNPPLSSTVTVRLFVLDLNDNAPAVLRP 568
           S+N  TG ++A +SFDYEQ + LQ  V A D G+PPLSS +++ LFVLD NDNAP +L P
Sbjct: 506 SINSDTGVLYALQSFDYEQIRDLQLLVTASDSGDPPLSSNMSLSLFVLDQNDNAPEILYP 565

Query: 569 R-ARPGSLCPQALPPSVGAGHLITKVTAVDLDSGYNAWVSYQLLEAPDPSLFAVSRYAGE 627
                GS   +  P S   G+L+TKV AVD DSG NAW+SY+LL+A +P LF+V  + GE
Sbjct: 566 ALPTDGSTGVELAPRSAERGYLVTKVVAVDRDSGQNAWLSYRLLKASEPGLFSVGLHTGE 625

Query: 628 VRTA-VPIPADLPPQKLVIVVKDSGSPPLSTSVTLLVSLEEDTHPVVPDLRE-SSAPREG 685
           VRTA   +  D   Q LV+ V+D G PPLS +VTL V++ +    V+ +L     +    
Sbjct: 626 VRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADSIPEVLTELGSLKPSVDPN 685

Query: 686 ESRLTLYLAVSLVAICFVSFGSFVALLSKCLRGAACGVTCFPAGTCACLTRSRRREGLPP 745
           +S LTLYL V++ AI  V       LL   LR          +G         R  G+P 
Sbjct: 686 DSSLTLYLVVAVAAISCVFLAFVAVLLGLRLRRWHKSRLLQDSG--------GRLVGVPA 737

Query: 746 SN--GILRIQLGSDDPIKFVDVGGHSHGCTPLASAPTRSDSFMMVKSPSAPMAGEPVRPS 803
           S+  G+  +Q       + V +   S     +   P  +D   M+ S       + +  S
Sbjct: 738 SHFVGVEEVQAFLQTYSQEVSLTADSRKSHLIFPQPNYAD---MLISQEGCEKNDSLLTS 794

Query: 804 CP----PSDLLYGLEQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQFDTEMLQAMIL 859
                  ++  +G +QAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQFDTEMLQAMIL
Sbjct: 795 VDFHEYKNEADHG-QQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQFDTEMLQAMIL 853

Query: 860 ASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATLTNAAGKRDG 919
           ASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATLTNAAGKRDG
Sbjct: 854 ASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATLTNAAGKRDG 913

Query: 920 KAPAGGNGNKKKSGKKEKK 938
           KAPAGGNGNKKKSGKKEKK
Sbjct: 914 KAPAGGNGNKKKSGKKEKK 932


>gi|11128043 protocadherin gamma subfamily A, 9 isoform 1 precursor
           [Homo sapiens]
          Length = 932

 Score =  795 bits (2053), Expect = 0.0
 Identities = 443/924 (47%), Positives = 587/924 (63%), Gaps = 36/924 (3%)

Query: 30  QIRYPVPEESQEGTFVGNVAQDFLLDTDSLSARRLQVAGEVNQRHFRVDLDSGALLIKNP 89
           QIRY VPEE+++G  VGN+++D  L+   L+ RR+++      + F ++  SG L+    
Sbjct: 30  QIRYSVPEETEKGYIVGNISKDLALEPRELAERRVRIVSRGRTQLFSLNPRSGTLVTAGR 89

Query: 90  IDREALCGLSASCIVPLEFVTEGPLEMYRAEVEIVDVNDHAPRFPRQQLDLEIGEAAPPG 149
           IDRE LC  S  C+V  + + E  +++Y  E+E+ D+ND AP+F  + L+++I E A PG
Sbjct: 90  IDREELCAQSPRCLVNFKVLVEDRVKLYGIEIEVTDINDSAPKFQAESLEVKINEIAVPG 149

Query: 150 QRFPLEKAQDADVGSNSISSYRLSSNEHFALDVKKRSDGSLVPELLLEKPLDREKQSDYR 209
            R+PL +A D DVG NS+ SY+LS N HF+L+V+   +G++ PEL+LE+ LDRE+ + + 
Sbjct: 150 ARYPLPEAIDPDVGVNSLQSYQLSPNHHFSLNVQTGDNGAINPELVLERALDREEATAHH 209

Query: 210 LVLTAVDGGNPPRSGTAELRVSVLDVNDNAPAFQQSSYRISVLESAPAGMVLIQLNASDP 269
           LVLTA DGG P RS T  + V+VLD NDNAP F Q  YR+ VLE+ P G  L+   ASD 
Sbjct: 210 LVLTASDGGEPRRSSTVRIHVTVLDTNDNAPVFAQRIYRVKVLENVPPGTWLLTATASDL 269

Query: 270 DLGPSGNVTFYFSGHTPDRVRNLFSLHPTTGKLTLLGPLDFESENYYEFDVRARDGGSPA 329
           D G +G V + F     ++   LF L+  TG+++    LD+E  ++YE +++A DGG   
Sbjct: 270 DEGINGKVAYKF-WKINEKQSLLFQLNENTGEISTAKSLDYEECSFYEMEIQAEDGG--G 326

Query: 330 MEQHCSLRVDLLDVNDNAPYITVTSELGTLPESAEPGTVVALISVQDPDSGSNGDVSLRI 389
           ++    + + + DVNDN P +T+TS    + E A  GTV+ L +  D DSG NG V   I
Sbjct: 327 LKGWTKVLISVEDVNDNRPEVTITSLFSPVREDAPQGTVILLFNAHDRDSGKNGQVVCSI 386

Query: 390 PDHLPFALKSAFRNQFSLVTAGPLDREAKSSYDIMVTASDAGNPPLSTHRTIFLNISDVN 449
            ++L F L+++  + + L+TA  LDRE  S Y+I VTA+D G PPLST   I L ++D+N
Sbjct: 387 QENLSFTLENSEEDYYRLLTAQILDREKASEYNITVTATDRGTPPLSTEIHITLQVTDIN 446

Query: 450 DNPPSFFQRSHEVFVPENNRPGDLLCSLAASDPDSGLNALISYSLLEPRNRDVSASSFIS 509
           DNPP+F Q S+ V++PENN  G  + S+ A DPDS  N+ + YSL E   +    S+++S
Sbjct: 447 DNPPAFSQASYSVYLPENNARGTSIFSVIAYDPDSNENSRVIYSLAEDTIQGSPLSTYVS 506

Query: 510 LNPQTGAVHATRSFDYEQTQTLQFEVQARDRGNPPLSSTVTVRLFVLDLNDNAPAVLRPR 569
           +N  TG ++A  SFDYEQ + LQ +V A D G+PPLSS V++RLFVLD NDNAP +L P 
Sbjct: 507 INSDTGVLYALCSFDYEQFRDLQMQVTASDSGSPPLSSNVSLRLFVLDQNDNAPEILYPA 566

Query: 570 -ARPGSLCPQALPPSVGAGHLITKVTAVDLDSGYNAWVSYQLLEAPDPSLFAVSRYAGEV 628
               GS   +  P S   G+L+TKV AVD DSG NAW+SY+L +A +P LF+V  + GEV
Sbjct: 567 LPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSYRLFKASEPGLFSVGLHTGEV 626

Query: 629 RTA-VPIPADLPPQKLVIVVKDSGSPPLSTSVTLLVSLEEDTHPVVPDLRESSAPREGE- 686
           RTA   +  D   Q LV+ V+D G PPLS +VTL V++ +    ++ DL     P + E 
Sbjct: 627 RTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAIADSIPDILADLGSLQIPADLEA 686

Query: 687 SRLTLYLAVSLVAICFVSFGSFVALLSKCLRGAACGVTCFPAGTCACLTRSRRREGLPPS 746
           S LTLYL V++  +  V     + LL+  LR            +      S    G+P S
Sbjct: 687 SDLTLYLVVAVAVVSCVFLTFVITLLALRLR--------HWHSSHLLRATSDGLAGVPTS 738

Query: 747 NGILRIQLGSDDPIKFVDVGGHSHGCTPLASAPTRSDSFMMVKSPS------APMAGEPV 800
           + +     G D    F+         T    A +R  S ++   P+      +  + E  
Sbjct: 739 HFV-----GVDGVRAFLQTYSQEFSLT----ADSRK-SHLIFPQPNYADTLISQQSCEKN 788

Query: 801 RPSCPPSDLLYGLE------QAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQFDTEML 854
            P C   D  + +E      QAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQFDTEML
Sbjct: 789 EPLCVSVDSKFPIEDTPLVPQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQFDTEML 848

Query: 855 QAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATLTNAA 914
           QAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATLTNAA
Sbjct: 849 QAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATLTNAA 908

Query: 915 GKRDGKAPAGGNGNKKKSGKKEKK 938
           GKRDGKAPAGGNGNKKKSGKKEKK
Sbjct: 909 GKRDGKAPAGGNGNKKKSGKKEKK 932


>gi|11056063 protocadherin gamma subfamily A, 7 isoform 1 precursor
           [Homo sapiens]
          Length = 932

 Score =  793 bits (2047), Expect = 0.0
 Identities = 445/932 (47%), Positives = 588/932 (63%), Gaps = 50/932 (5%)

Query: 29  GQIRYPVPEESQEGTFVGNVAQDFLLDTDSLSARRLQVAGEVNQRHFRVDLDSGALLIKN 88
           G+I Y V EE+ +G+FVG++A+D  L+   L+ R +++      + F ++  SG+L+   
Sbjct: 29  GRILYSVSEETDKGSFVGDIAKDLGLEPRELAERGVRIISRGRTQLFALNQRSGSLVTAG 88

Query: 89  PIDREALCGLSASCIVPLEFVTEGPLEMYRAEVEIVDVNDHAPRFPRQQLDLEIGEAAPP 148
            IDRE +C  SA C+V    + E  + +Y  +VEI+D+ND+ PRF  ++++++I E   P
Sbjct: 89  RIDREEICAQSARCLVNFNILMEDKMNLYPIDVEIIDINDNVPRFLTEEINVKIMENTAP 148

Query: 149 GQRFPLEKAQDADVGSNSISSYRLSSNEHFALDVKKRSDGSLVPELLLEKPLDREKQSDY 208
           G RFPL +A D DVG+NS+ SY+LS N HF+L V+   D +  PEL+LE+ LDRE++  +
Sbjct: 149 GVRFPLSEAGDPDVGTNSLQSYQLSPNRHFSLAVQSGDDETKYPELVLERVLDREEERVH 208

Query: 209 RLVLTAVDGGNPPRSGTAELRVSVLDVNDNAPAFQQSSYRISVLESAPAGMVLIQLNASD 268
            LVLTA DGG+PPRS TA ++V+V+DVND+ P F    Y+++V E+ P G  L+ ++A D
Sbjct: 209 HLVLTASDGGDPPRSSTAHIQVTVVDVNDHTPVFSLPQYQVTVPENVPVGTRLLTVHAID 268

Query: 269 PDLGPSGNVTFYFSGHTPDRVRNLFSLHPTTGKLTLLGPLDFESENYYEFDVRARDGGSP 328
            D G +G VT+ F   TP ++  +F L+  TG+++ L  LD+E   +YE +V+A+DG  P
Sbjct: 269 LDEGVNGEVTYSFRKITP-KLPKMFHLNSLTGEISTLEGLDYEETAFYEMEVQAQDG--P 325

Query: 329 AMEQHCSLRVDLLDVNDNAPYITVTSELGTLPESAEPGTVVALISVQDPDSGSNGDVSLR 388
                  + + +LDVNDNAP +T+TS   ++PE    GTV+AL  +QD DSG NG+V+  
Sbjct: 326 GSLTKAKVLITVLDVNDNAPEVTMTSLSSSIPEDTPLGTVIALFYLQDRDSGKNGEVTCT 385

Query: 389 IPDHLPFALKSAFRNQFSLVTAGPLDREAKSSYDIMVTASDAGNPPLSTHRTIFLNISDV 448
           IP++LPF L+ +  N + LVT   LDRE  S Y+I + A+D G PPLS    IF+ ++D 
Sbjct: 386 IPENLPFKLEKSIDNYYRLVTTKNLDRETLSLYNITLKATDGGTPPLSRETHIFMQVADT 445

Query: 449 NDNPPSFFQRSHEVFVPENNRPGDLLCSLAASDPDSGLNALISYSLLEPRNRDVSASSFI 508
           NDNPP+F   S+ V++ ENN  G  +  + A D DS  NA I+YSL E   +    SS++
Sbjct: 446 NDNPPTFPHSSYSVYIAENNPRGASIFLVTAQDHDSEDNAQITYSLAEDTIQGAPVSSYV 505

Query: 509 SLNPQTGAVHATRSFDYEQTQTLQFEVQARDRGNPPLSSTVTVRLFVLDLNDNAPAVLRP 568
           S+N  TG ++A +SFDYEQ + LQ  V A D G+PPLSS +++ LFVLD NDN P +L P
Sbjct: 506 SINSDTGVLYALQSFDYEQLRELQLRVTAHDSGDPPLSSNMSLSLFVLDQNDNPPEILYP 565

Query: 569 R-ARPGSLCPQALPPSVGAGHLITKVTAVDLDSGYNAWVSYQLLEAPDPSLFAVSRYAGE 627
                GS   +  P S   G+L+TKV AVD DSG NAW+SY LL+A +P LFAV  Y GE
Sbjct: 566 ALPTDGSTGMELAPRSAEPGYLVTKVVAVDKDSGQNAWLSYLLLKASEPGLFAVGLYTGE 625

Query: 628 VRTA-VPIPADLPPQKLVIVVKDSGSPPLSTSVTLLVSLEEDTHPVVPDLRESSAPREGE 686
           VRTA   +  D   Q LV+ V+D G PPLS +VTL V++ +    V+ DL  S  P +G 
Sbjct: 626 VRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADSIPEVLADL-GSLEPSDGP 684

Query: 687 SR--LTLYLAVSLVAICFVSFGSFVALLSKCLRGAACGVTCFPAGTCACLTRSRRREGLP 744
               LTLYL V++  +  V     + LL+  LR                  R  +   L 
Sbjct: 685 YNYDLTLYLVVAVATVSCVFLAFVLVLLALRLR------------------RWHKSRLLQ 726

Query: 745 PSNGILRIQ-----LGSDDPIKFVDVGGHSHGCTPLASAPTRSDSFMMVKSPSAPMAGEP 799
            S G L        +G D    F+    H    T    A +R    +  +     M    
Sbjct: 727 ASEGGLANVPTSHFVGMDGVQAFLQTYSHEVSLT----ADSRKSHLIFPQPNYVDMLIS- 781

Query: 800 VRPSCPPSDLLY-------------GLEQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPN 846
            + SC  +D L               ++QAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPN
Sbjct: 782 -QESCEKNDSLLTSVDFQECKENLPSIQQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPN 840

Query: 847 NQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGS 906
           NQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGS
Sbjct: 841 NQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGS 900

Query: 907 NATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK 938
           NATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK
Sbjct: 901 NATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK 932


>gi|11128033 protocadherin gamma subfamily B, 3 isoform 1 precursor
           [Homo sapiens]
          Length = 929

 Score =  786 bits (2031), Expect = 0.0
 Identities = 445/936 (47%), Positives = 578/936 (61%), Gaps = 40/936 (4%)

Query: 18  LFLFYHLGYVCGQ-IRYPVPEESQEGTFVGNVAQDFLLDTDSLSARRLQVAGEVNQRHFR 76
           LFL   L  V  + IRY +PEE   G+ VGN+A+D       L  R L+V  E  ++ F 
Sbjct: 19  LFLLSLLDQVLSEPIRYAIPEELDRGSLVGNLAKDLGFGVGDLPTRNLRVIAE--KKFFT 76

Query: 77  VDLDSGALLIKNPIDREALCGLSASCIVPLEFVTEGPLEMYRAEVEIVDVNDHAPRFPRQ 136
           V  ++G LL+ + IDRE +CG  ++C++  E V E PL  +   V I D+ND+ P F + 
Sbjct: 77  VSPENGNLLVSDRIDREEICGKKSTCVLEFEMVAEKPLNFFHVTVLIQDINDNPPTFSQN 136

Query: 137 QLDLEIGEAAPPGQRFPLEKAQDADVGSNSISSYRLSSNEHFALDVKKRSDGSLVPELLL 196
             +LEI E A  G  F LE AQD DVG NS+  Y LS + HF+L  K+  DGS  PEL+L
Sbjct: 137 ITELEISELALTGATFALESAQDPDVGVNSLQQYYLSPDPHFSLIQKENLDGSRYPELVL 196

Query: 197 EKPLDREKQSDYRLVLTAVDGGNPPRSGTAELRVSVLDVNDNAPAFQQSSYRISVLESAP 256
           + PLDRE+Q  + LVLTAVDGG P RS T ++RV V D NDN P F Q  YR++V E+ P
Sbjct: 197 KAPLDREEQPHHHLVLTAVDGGEPSRSCTTQIRVIVADANDNPPVFTQDMYRVNVAENLP 256

Query: 257 AGMVLIQLNASDPDLGPSGNVTFYFSGHTPDRVRNLFSLHPTTGKLTLLGPLDFESENYY 316
           AG  ++++ A D D G +  + + F  +    VR LF L   TG+LT +G LDFE  + Y
Sbjct: 257 AGSSVLKVMAIDMDEGINAEIIYAFI-NIGKEVRQLFKLDSKTGELTTIGELDFEERDSY 315

Query: 317 EFDVRARDGGSPAMEQHCSLRVDLLDVNDNAPYITVTSELGTLPESAEPGTVVALISVQD 376
              V A+DGG      +C +++D+ D NDNAP IT+ SE   + E AE GT VALI   D
Sbjct: 316 TIGVEAKDGGHHTA--YCKVQIDISDENDNAPEITLASESQHIQEDAELGTAVALIKTHD 373

Query: 377 PDSGSNGDVSLRIPDHLPFALKSAFRNQFSLVTAGPLDREAKSSYDIMVTASDAGNPPLS 436
            DSG NG++  ++  + PF +    +N + LVT G LDRE    Y++ +TA+D GNPPLS
Sbjct: 374 LDSGFNGEILCQLKGNFPFKIVQDTKNTYRLVTDGALDREQIPEYNVTITATDKGNPPLS 433

Query: 437 THRTIFLNISDVNDNPPSFFQRSHEVFVPENNRPGDLLCSLAASDPDSGLNALISYSL-- 494
           + +TI L+I DVNDN P F Q S+ V V ENN PG  +  + ASDPD G N L+SY +  
Sbjct: 434 SSKTITLHILDVNDNVPVFHQASYTVHVAENNPPGASIAHVRASDPDLGPNGLVSYYIVA 493

Query: 495 --LEPRNRDVSASSFISLNPQTGAVHATRSFDYEQTQTLQFEVQARDRGNPPLSSTVTVR 552
             LEPR      SS++S++ ++G V A R+FD+EQ +  +  +QARD+G+P LS+ V++R
Sbjct: 494 SDLEPRE----LSSYVSVSARSGVVFAQRAFDHEQLRAFELTLQARDQGSPTLSANVSLR 549

Query: 553 LFVLDLNDNAPAVLRPRARP-GSLCPQALPPSVGAGHLITKVTAVDLDSGYNAWVSYQLL 611
           + V D NDNAP VL P   P GS     +P S   G+L+TKV AVD DSGYNAW+SY ++
Sbjct: 550 VLVDDRNDNAPLVLYPALGPEGSALFDMVPRSAEPGYLVTKVVAVDADSGYNAWLSYHIV 609

Query: 612 EAPDPSLFAVSRYAGEVRTAVPI-PADLPPQKLVIVVKDSGSPPLSTSVTLLVSLEEDTH 670
           +A +P LF++    GEVRTA  +   +   Q+L++ V+D G  PLS +V L +   +   
Sbjct: 610 QASEPGLFSLGLRTGEVRTARTLGDREAARQRLLVTVRDGGQQPLSATVMLHLIFADSLQ 669

Query: 671 PVVPDLRESSAPREGESRLTLYLAVSLVAICFVSFGSFVALLSKCLRGAACGVT------ 724
            + PDL +   P + ++ L  +L V+L  I  +   + +  +S  LR ++   T      
Sbjct: 670 EIQPDLSDRPTPSDPQAELQFHLVVALALISVLFLLAVILAISLRLRCSSRPATEGYFQP 729

Query: 725 --CFPAGTCACLTRSRRREGLPPSNGILRIQLGSDDPIKFVDVGGHSHGCTPLASAPTRS 782
             CF        T S R   LP S         S+   KF+++   +    P       +
Sbjct: 730 GVCFKTVPGVLPTYSERT--LPYSYNPCAASHSSNTEFKFLNI--KAENAAPQDLLCDEA 785

Query: 783 DSFMMVKSPSAPMAGEPVRPSCPPSDLLYGLEQAPPNTDWRFSQAQRPGTSGSQNGDDTG 842
             F    +P  P     ++            +QAPPNTDWRFSQAQRPGTSGSQNGDDTG
Sbjct: 786 SWFESNDNPEMPSNSGNLQ------------KQAPPNTDWRFSQAQRPGTSGSQNGDDTG 833

Query: 843 TWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVY 902
           TWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVY
Sbjct: 834 TWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVY 893

Query: 903 IPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK 938
           IPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK
Sbjct: 894 IPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK 929


>gi|14277685 protocadherin gamma subfamily C, 5 isoform 2 precursor
           [Homo sapiens]
          Length = 878

 Score =  678 bits (1750), Expect = 0.0
 Identities = 365/746 (48%), Positives = 492/746 (65%), Gaps = 13/746 (1%)

Query: 25  GYVCGQIRYPVPEESQEGTFVGNVAQDFLLDTDSLSARRLQVAGEVNQRHFRVDLDSGAL 84
           G+V GQ+RY V EES+ GT VGNVAQD  L    L +RRLQ+  E N R+F + L SGAL
Sbjct: 25  GWVSGQLRYSVVEESEPGTLVGNVAQDLGLKMTDLLSRRLQLGSEENGRYFSLSLMSGAL 84

Query: 85  LIKNPIDREALCGLSASCIVPLEFVTEGPLEMYRAEVEIVDVNDHAPRFPRQQLDLEIGE 144
            +   IDRE+LCG S SC++P++ VTE PLE+ R EVEI+D+ND++P F   + ++ I E
Sbjct: 85  AVNQKIDRESLCGASTSCLLPVQVVTEHPLELIRVEVEILDLNDNSPSFATPEREMRISE 144

Query: 145 AAPPGQRFPLEKAQDADVGSNSISSYRLSSNEHFALDVKKRSDGSLVPELLLEKPLDREK 204
           +A  G RFPL+ AQD DVG+N++S Y LS N HF+L+VK   DG   PEL+LE+ LDRE 
Sbjct: 145 SAASGARFPLDSAQDPDVGTNTVSFYTLSPNSHFSLNVKTLKDGKPFPELVLEQQLDREA 204

Query: 205 QSDYRLVLTAVDGGNPPRSGTAELRVSVLDVNDNAPAFQQSSYRISVLESAPAGMVLIQL 264
           Q+ ++LVLTAVDGG P RSGT  + V VLD+NDNAP FQ S  R+ + E+AP G +L++L
Sbjct: 205 QARHQLVLTAVDGGTPARSGTTLISVIVLDINDNAPTFQSSVLRVGIPENAPIGTLLLRL 264

Query: 265 NASDPDLGPSGNVTFYFSGHTPDRVRNLFSLHPTTGKLTLLGPLDFESENYYEFDVRARD 324
           NA+DPD G +G + + F  HT + VRNLF L P++G + +LGP+DFE   +YE   RARD
Sbjct: 265 NATDPDEGTNGQLDYSFGDHTSEAVRNLFGLDPSSGAIHVLGPIDFEESRFYEIHARARD 324

Query: 325 GGSPAMEQHCSLRVDLLDVNDNAPYITVTSELGTLPESAEPGTVVALISVQDPDSGSNGD 384
            G PAME HC ++VD+ DVNDNAP + + S    + ES   GTVV L +V+D DSG NG+
Sbjct: 325 QGQPAMEGHCVIQVDVGDVNDNAPEVLLASLANPVLESTPVGTVVGLFNVRDRDSGRNGE 384

Query: 385 VSLRIPDHLPFALKSAFRNQFSLVTAGPLDREAKSSYDIMVTASDAGNPPLSTHRTIFLN 444
           VSL I   LPF +K +  N +SL+T+ PLDREA S Y I + ASDAG+P L  H TI LN
Sbjct: 385 VSLDISPDLPFQIKPS-ENHYSLLTSQPLDREATSHYIIELLASDAGSPSLHKHLTIRLN 443

Query: 445 ISDVNDNPPSFFQRSHEVFVPENNRPGDLLCSLAASDPDSGLNALISYSLLEPRNRDVSA 504
           ISDVNDN P F Q+ +  ++ EN  PG LLC++AASDPD+G NA ++YS++  + +   A
Sbjct: 444 ISDVNDNAPRFNQQLYTAYILENRPPGSLLCTVAASDPDTGDNARLTYSIVGNQVQGAPA 503

Query: 505 SSFISLNPQTGAVHATRSFDYEQTQTLQFEVQARDRGNPPLSSTVTVRLFVLDLNDNAPA 564
           SSF+ +NP+ G + A R+FDYE  Q LQ  V  RD G+PPL +  ++ +FVLD NDNAPA
Sbjct: 504 SSFVYVNPEDGRIFAQRTFDYELLQMLQIVVGVRDSGSPPLHANTSLHVFVLDENDNAPA 563

Query: 565 VLRPRARPGSLCPQALPPSVGAGHLITKVTAVDLDSGYNAWVSYQLL-EAPDPSLFAVSR 623
           VL PR       PQ LP S   G L+TKVTAVD D+G+NAW+SY LL ++  P LF VS 
Sbjct: 564 VLHPRPDWEHSAPQRLPRSAPPGSLVTKVTAVDADAGHNAWLSYSLLPQSTAPGLFLVST 623

Query: 624 YAGEVRTA-VPIPADLPPQKLVIVVKDSGSPPLSTSVTLLVSLEEDTHPVVPDLRESSAP 682
           + GEVRTA   +  D   Q++V++V+D+G P LS++ T+L+ LE++    +P   +    
Sbjct: 624 HTGEVRTARALLEDDSDTQQVVVLVRDNGDPSLSSTATVLLVLEDEDPEEMPKSSDFLIH 683

Query: 683 REGESRLTLYLAVSLVAICFVSFGSFVALLSKCLRGAACGVTCFPAGTCACLTRSRRREG 742
               S LTLYL V+L  +  +S  +F  L +KCL+G A G      G   C    RR++ 
Sbjct: 684 PPERSDLTLYLIVALATVSLLSLVTFTFLSAKCLQGNADG----DGGGGQC---CRRQDS 736

Query: 743 LPP---SNGILRIQLGSDDPIKFVDV 765
             P         +Q+ SD  +K+++V
Sbjct: 737 PSPDFYKQSSPNLQVSSDGTLKYMEV 762


>gi|9256600 protocadherin alpha subfamily C, 2 isoform 1 precursor
           [Homo sapiens]
          Length = 1007

 Score =  627 bits (1617), Expect = e-179
 Identities = 372/965 (38%), Positives = 552/965 (57%), Gaps = 52/965 (5%)

Query: 17  LLFLFYHLGYVCGQIRYPVPEESQEGTFVGNVAQDFLLDTDSLSARRLQV--AGEVNQRH 74
           LL L    G    Q+RY VPEE   G  VGNVA+   L+   L    L++   G  + R+
Sbjct: 30  LLLLLLLPGPAASQLRYSVPEEQAPGALVGNVARALGLELRRLGPGCLRINHLGAPSPRY 89

Query: 75  FRVDLDSGALLIKNPIDREALCGLSASCIVPLEFVTEGPLEMYRAEVEIVDVNDHAPRFP 134
             +DL SGAL +   IDREALC     C++ LE +   P+ +   EVEI+D+ND++PRFP
Sbjct: 90  LELDLTSGALFVNERIDREALCEQRPRCLLSLEVLAHNPVAVSAVEVEILDINDNSPRFP 149

Query: 135 RQQLDLEIGEAAPPGQRFPLEKAQDADVGSNSISSYRLSSNEHFALDVKKRSDGSLVPEL 194
           R    L++ E+  PG RF +E AQD DVG+NS+ +Y LS +EHF LD+K   + S V EL
Sbjct: 150 RPNYQLQVSESVAPGARFHIESAQDPDVGANSVQTYELSPSEHFELDLKPLQENSKVLEL 209

Query: 195 LLEKPLDREKQSDYRLVLTAVDGGNPPRSGTAELRVSVLDVNDNAPAFQQSSYRISVLES 254
           +L K LDRE+ + + LVLTAVDGG P RSGTA++ V VLD NDN+PAF QS+YR+ + E 
Sbjct: 210 VLRKGLDREQAALHHLVLTAVDGGIPARSGTAQISVRVLDTNDNSPAFDQSTYRVQLRED 269

Query: 255 APAGMVLIQLNASDPDLGPSGNVTFYFSGHTPDRVRNLFSLHPTTGKLTLLGPLDFESEN 314
           +P G ++++LNASDPD G +G + +  S +T DR R LFS+  +TG++ ++G LD+E  +
Sbjct: 270 SPPGTLVVKLNASDPDEGSNGELRYSLSSYTSDRERQLFSIDASTGEVRVIGGLDYEEAS 329

Query: 315 YYEFDVRARDGGSPAMEQHCSLRVDLLDVNDNAPYITVTSELGTLPESAEPGTVVALISV 374
            Y+  V+A D G   M  HC + VD++DVNDNAP + +T     +PE+A P T+VA++SV
Sbjct: 330 SYQIYVQATDRGPVPMAGHCKVLVDIVDVNDNAPEVVLTDLYSPVPENATPNTIVAVLSV 389

Query: 375 QDPDSGSNGDVSLRIPDHLPFALKSAFRNQFSLVTAGPLDREAKSSYDIMVTASDAGNPP 434
            D DSG N  VSL +   LPF L + F N ++LV +GPLDRE  + Y+I VTA+D G P 
Sbjct: 390 NDQDSGPNRKVSLGLEATLPFRL-NGFGNSYTLVVSGPLDRERVAVYNITVTATDGGIPQ 448

Query: 435 LSTHRTIFLNISDVNDNPPSFFQRSHEVFVPENNRPGDLLCSLAASDPDSGLNALISYSL 494
           L++ RT+ + ISD+NDNPPSF + S+ +++ ENN PG LLC++ A+DPD   NA ++YSL
Sbjct: 449 LTSLRTLKVEISDINDNPPSFLEDSYSIYIQENNLPGVLLCTVQATDPDEKENAEVTYSL 508

Query: 495 LEPRNRDVSASSFISLNPQTGAVHATRSFDYEQTQTLQFEVQARDRGNPPLSSTVTVRLF 554
           LE   + +  +S++S+N  +G+++A  SFDYE+ +     V+A+D+G+PPLSSTVT  ++
Sbjct: 509 LEREIQGLPVTSYVSINSASGSLYAVNSFDYEKFREFFVTVEAQDKGSPPLSSTVTANVY 568

Query: 555 VLDLNDNAPAVLRPRARPGSLCPQALPPSVGAGHLITKVTAVDLDSGYNAWVSYQLLEAP 614
           V+D+ND+AP +L P +   S   + +P +  AG+L+TKV A+D DSG NAW+ Y L +  
Sbjct: 569 VVDMNDHAPHILYPTSTNSSAAFEMVPRTAPAGYLVTKVIAMDSDSGQNAWLFYHLAQTS 628

Query: 615 DPSLFAVSRYAGEVRTAVPIPADLPPQ-KLVIVVKDSGSPPLSTSVTLLVSLEEDTHPVV 673
           D  LF V  + GE+RT   +  +      L +VV+D+G P LS SV + V++ +    ++
Sbjct: 629 DLDLFKVELHTGEIRTTRKMGDESGSTFNLTVVVRDNGEPSLSASVAITVAVVDRVSKIL 688

Query: 674 PDLRESSAPREGESRLTLYLAVSLVAICFVSFGSFVAL-LSKCLRGAACGVTCFPAGTCA 732
           PD +         S +TLYL ++L  + F+   + + L + KC R  A G  C   G C 
Sbjct: 689 PDTQRHVKSPRTYSEITLYLIIALSTVSFIFLLTIIILSIIKCYRYTAYGTACC-GGFCG 747

Query: 733 CLTRSRRREGLPPSNGI-LRIQLGSDDPIKFVDVGGH-----SHGCTPLASAPTRSDSFM 786
              RS        +N I  RI  G      F++V G+     ++      +A + SD+FM
Sbjct: 748 VRERSPAELYKQANNNIDARIPHGLKVQPHFIEVRGNGSLTKTYCYKACLTAGSGSDTFM 807

Query: 787 MVKSPSAPMAG-EPVRPSCPPSDLLYGL-------------------EQAPPNTDWRFSQ 826
              + +    G    + +   S  L G                    E   PN DWR+S 
Sbjct: 808 FYNTGAQTGPGPSGAQAAVTDSRNLTGQSGQNAGNLIILKNEAVSQNEPRQPNPDWRYSA 867

Query: 827 AQRPGTSGSQNGDDTGT------WPNNQFDTEMLQAMILASAS---EAADGSSTLGGGAG 877
           + R G   S + ++ G        P+ Q+ T       ++SA+   EA + S  +G G  
Sbjct: 868 SLRAGMHSSVHLEEAGILRAGPGGPDQQWPT-------VSSATPEPEAGEVSPPVGAGVN 920

Query: 878 TMGLSARYGPQFTLQHVP-DYRQNVYIPGSNATLT---NAAGKRDGKAPAGGNGNKKKSG 933
           +   + +YGP    Q  P +      IPGS A ++        +  K+     G K+++ 
Sbjct: 921 SNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKKEETK 980

Query: 934 KKEKK 938
           KK+KK
Sbjct: 981 KKKKK 985


>gi|14165431 protocadherin alpha subfamily C, 2 isoform 2 precursor
           [Homo sapiens]
          Length = 884

 Score =  607 bits (1564), Expect = e-173
 Identities = 330/780 (42%), Positives = 482/780 (61%), Gaps = 12/780 (1%)

Query: 17  LLFLFYHLGYVCGQIRYPVPEESQEGTFVGNVAQDFLLDTDSLSARRLQV--AGEVNQRH 74
           LL L    G    Q+RY VPEE   G  VGNVA+   L+   L    L++   G  + R+
Sbjct: 30  LLLLLLLPGPAASQLRYSVPEEQAPGALVGNVARALGLELRRLGPGCLRINHLGAPSPRY 89

Query: 75  FRVDLDSGALLIKNPIDREALCGLSASCIVPLEFVTEGPLEMYRAEVEIVDVNDHAPRFP 134
             +DL SGAL +   IDREALC     C++ LE +   P+ +   EVEI+D+ND++PRFP
Sbjct: 90  LELDLTSGALFVNERIDREALCEQRPRCLLSLEVLAHNPVAVSAVEVEILDINDNSPRFP 149

Query: 135 RQQLDLEIGEAAPPGQRFPLEKAQDADVGSNSISSYRLSSNEHFALDVKKRSDGSLVPEL 194
           R    L++ E+  PG RF +E AQD DVG+NS+ +Y LS +EHF LD+K   + S V EL
Sbjct: 150 RPNYQLQVSESVAPGARFHIESAQDPDVGANSVQTYELSPSEHFELDLKPLQENSKVLEL 209

Query: 195 LLEKPLDREKQSDYRLVLTAVDGGNPPRSGTAELRVSVLDVNDNAPAFQQSSYRISVLES 254
           +L K LDRE+ + + LVLTAVDGG P RSGTA++ V VLD NDN+PAF QS+YR+ + E 
Sbjct: 210 VLRKGLDREQAALHHLVLTAVDGGIPARSGTAQISVRVLDTNDNSPAFDQSTYRVQLRED 269

Query: 255 APAGMVLIQLNASDPDLGPSGNVTFYFSGHTPDRVRNLFSLHPTTGKLTLLGPLDFESEN 314
           +P G ++++LNASDPD G +G + +  S +T DR R LFS+  +TG++ ++G LD+E  +
Sbjct: 270 SPPGTLVVKLNASDPDEGSNGELRYSLSSYTSDRERQLFSIDASTGEVRVIGGLDYEEAS 329

Query: 315 YYEFDVRARDGGSPAMEQHCSLRVDLLDVNDNAPYITVTSELGTLPESAEPGTVVALISV 374
            Y+  V+A D G   M  HC + VD++DVNDNAP + +T     +PE+A P T+VA++SV
Sbjct: 330 SYQIYVQATDRGPVPMAGHCKVLVDIVDVNDNAPEVVLTDLYSPVPENATPNTIVAVLSV 389

Query: 375 QDPDSGSNGDVSLRIPDHLPFALKSAFRNQFSLVTAGPLDREAKSSYDIMVTASDAGNPP 434
            D DSG N  VSL +   LPF L + F N ++LV +GPLDRE  + Y+I VTA+D G P 
Sbjct: 390 NDQDSGPNRKVSLGLEATLPFRL-NGFGNSYTLVVSGPLDRERVAVYNITVTATDGGIPQ 448

Query: 435 LSTHRTIFLNISDVNDNPPSFFQRSHEVFVPENNRPGDLLCSLAASDPDSGLNALISYSL 494
           L++ RT+ + ISD+NDNPPSF + S+ +++ ENN PG LLC++ A+DPD   NA ++YSL
Sbjct: 449 LTSLRTLKVEISDINDNPPSFLEDSYSIYIQENNLPGVLLCTVQATDPDEKENAEVTYSL 508

Query: 495 LEPRNRDVSASSFISLNPQTGAVHATRSFDYEQTQTLQFEVQARDRGNPPLSSTVTVRLF 554
           LE   + +  +S++S+N  +G+++A  SFDYE+ +     V+A+D+G+PPLSSTVT  ++
Sbjct: 509 LEREIQGLPVTSYVSINSASGSLYAVNSFDYEKFREFFVTVEAQDKGSPPLSSTVTANVY 568

Query: 555 VLDLNDNAPAVLRPRARPGSLCPQALPPSVGAGHLITKVTAVDLDSGYNAWVSYQLLEAP 614
           V+D+ND+AP +L P +   S   + +P +  AG+L+TKV A+D DSG NAW+ Y L +  
Sbjct: 569 VVDMNDHAPHILYPTSTNSSAAFEMVPRTAPAGYLVTKVIAMDSDSGQNAWLFYHLAQTS 628

Query: 615 DPSLFAVSRYAGEVRTAVPIPADLPPQ-KLVIVVKDSGSPPLSTSVTLLVSLEEDTHPVV 673
           D  LF V  + GE+RT   +  +      L +VV+D+G P LS SV + V++ +    ++
Sbjct: 629 DLDLFKVELHTGEIRTTRKMGDESGSTFNLTVVVRDNGEPSLSASVAITVAVVDRVSKIL 688

Query: 674 PDLRESSAPREGESRLTLYLAVSLVAICFVSFGSFVAL-LSKCLRGAACGVTCFPAGTCA 732
           PD +         S +TLYL ++L  + F+   + + L + KC R  A G  C   G C 
Sbjct: 689 PDTQRHVKSPRTYSEITLYLIIALSTVSFIFLLTIIILSIIKCYRYTAYGTACC-GGFCG 747

Query: 733 CLTRSRRREGLPPSNGI-LRIQLGSDDPIKFVDVGGH-----SHGCTPLASAPTRSDSFM 786
              RS        +N I  RI  G      F++V G+     ++      +A + SD+FM
Sbjct: 748 VRERSPAELYKQANNNIDARIPHGLKVQPHFIEVRGNGSLTKTYCYKACLTAGSGSDTFM 807


>gi|9256596 protocadherin alpha 8 isoform 1 precursor [Homo sapiens]
          Length = 950

 Score =  600 bits (1547), Expect = e-171
 Identities = 374/949 (39%), Positives = 536/949 (56%), Gaps = 54/949 (5%)

Query: 12  WRWATLLFLFYHLGYVCGQIRYPVPEESQEGTFVGNVAQDFLLDTDSLSARRLQVAGEVN 71
           WR   LL L        GQ+ Y VPEE++ GTFVG +AQD  L+   L  R  +VA + +
Sbjct: 12  WRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKRH 71

Query: 72  QRHFRVDLDSGALLIKNPIDREALCGLSASCIVPLEFVTEGPLEMYRAEVEIVDVNDHAP 131
           +    V L +G L + + IDRE LCG SA C + LE + + PL+++  +VE+ DVND+ P
Sbjct: 72  RDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDVNDNPP 131

Query: 132 RFPRQQLDLEIGEAAPPGQRFPLEKAQDADVGSNSISSYRLSSNEHFALDVKKRSDGSLV 191
            F  +   L + E+  P  RFPLE A DADVG+NS+ +YRLSS+++F LDV  ++D + +
Sbjct: 132 VFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFMLDVNSKNDENKL 191

Query: 192 PELLLEKPLDREKQSDYRLVLTAVDGGNPPRSGTAELRVSVLDVNDNAPAFQQSSYRISV 251
            EL+L K LDRE    + L LTA DGG P  +GT +L V+VLDVNDNAP F+QS Y + +
Sbjct: 192 VELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEVRI 251

Query: 252 LESAPAGMVLIQLNASDPDLGPSGNVTFYFSGHTPDRVRNLFSLHPTTGKLTLLGPLDFE 311
            E+A  G  +I+LNASDPD G +G +++ F+      V + FS+   TG++ + G LDFE
Sbjct: 252 FENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTGEIVIRGNLDFE 311

Query: 312 SENYYEFDVRARDGGSPAMEQHCSLRVDLLDVNDNAPYITVTSELGTLPESAEPGTVVAL 371
            EN Y+  + A D G P M  HC++ V +LD NDN P I +TS    + E A+ GTV+AL
Sbjct: 312 QENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTVIAL 371

Query: 372 ISVQDPDSGSNGDVSLRIPDHLPFALKSAFRNQFSLVTAGPLDREAKSSYDIMVTASDAG 431
           ISV D DSG+NG V+  +  H+PF L S F+N +SLV    LDRE  S+Y+++VTA D G
Sbjct: 372 ISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSAYELVVTARDGG 431

Query: 432 NPPLSTHRTIFLNISDVNDNPPSFFQRSHEVFVPENNRPGDLLCSLAASDPDSGLNALIS 491
           +P L    ++ + ++DVNDN P+F Q  + VFV ENN PG  + +++A D D+  NAL+S
Sbjct: 432 SPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENALVS 491

Query: 492 YSLLEPRNRDVSASSFISLNPQTGAVHATRSFDYEQTQTLQFEVQARDRGNPPLSSTVTV 551
           YSL+E R  + S SS+IS++ ++G V+A +  D+E+ + LQF+V ARD G PPL S VT+
Sbjct: 492 YSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTL 551

Query: 552 RLFVLDLNDNAPAVLRPR-ARPGSLCPQALPPSVGAGHLITKVTAVDLDSGYNAWVSYQL 610
           ++FVLD NDNAPA+L PR    G    + +P SVGAGH++ KV AVD DSGYNAW+SY+L
Sbjct: 552 QVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDADSGYNAWLSYEL 611

Query: 611 L-EAPDPSL-FAVSRYAGEVRTA-VPIPADLPPQKLVIVVKDSGSPPLSTSVTLLVSLEE 667
              A  P + F V  Y GE+ T  V   AD P  +L+++VKD G P L+ + T+LVSL E
Sbjct: 612 QPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVSLVE 671

Query: 668 DTHPVVPDLRESSAPREGESRLTLYLAVSLVAICFVSFGSFVALLSKCLRGAACGVTCFP 727
                    R+S+     E+ L       ++AIC VS    + LL             + 
Sbjct: 672 SGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTLL------------LYT 719

Query: 728 AGTCACL-TRSRRREGLPP---SNGILRIQLGSDDPIKFVDVGGHSHGCTPLASAPTRSD 783
           A  C+ L T    R G P    S+ +         P +     G           P ++D
Sbjct: 720 ALRCSALPTEGGCRAGKPTLVCSSAVGSWSYSQQQPQRVCSGEG-----------PPKTD 768

Query: 784 SFMMVKSPSAPM-AGEPVRPSCPPSDLLYGLEQAPPNTDWRFSQAQRPGTSGSQNGDDTG 842
             +M  SP  P   G          ++ +GL+   PN DWR+S + R G   S + ++ G
Sbjct: 769 --LMAFSPCLPPDLGSVDVGEEQDLNVDHGLKPRQPNPDWRYSASLRAGMHSSVHLEEAG 826

Query: 843 T------WPNNQFDTEMLQAMILASAS---EAADGSSTLGGGAGTMGLSARYGPQFTLQH 893
                   P+ Q+ T       ++SA+   EA + S  +G G  +   + +YGP    Q 
Sbjct: 827 ILRAGPGGPDQQWPT-------VSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQS 879

Query: 894 VP-DYRQNVYIPGSNATLT---NAAGKRDGKAPAGGNGNKKKSGKKEKK 938
            P +      IPGS A ++        +  K+     G K+++ KK+KK
Sbjct: 880 GPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKKEETKKKKKK 928


>gi|14196451 protocadherin gamma subfamily A, 11 isoform 2 precursor
           [Homo sapiens]
          Length = 837

 Score =  592 bits (1525), Expect = e-169
 Identities = 312/699 (44%), Positives = 457/699 (65%), Gaps = 6/699 (0%)

Query: 18  LFLFYHLGYVCGQIRYPVPEESQEGTFVGNVAQDFLLDTDSLSARRLQVAGEVNQRHFRV 77
           +FL    G+   QIRY VPEE+++G+FVGN+++D  L+   L+ R +++      + F V
Sbjct: 19  IFLGTLRGFRARQIRYSVPEETEKGSFVGNISKDLGLEPRELAKRGVRIVSRGKTQLFAV 78

Query: 78  DLDSGALLIKNPIDREALCGLSASCIVPLEFVTEGPLEMYRAEVEIVDVNDHAPRFPRQQ 137
           +  SG+L+    IDRE LC   +SC + +E + E  L++Y  EVEI+D+ND+AP F   +
Sbjct: 79  NPRSGSLITAGRIDREELCETVSSCFLNMELLVEDTLKIYGVEVEIIDINDNAPSFQEDE 138

Query: 138 LDLEIGEAAPPGQRFPLEKAQDADVGSNSISSYRLSSNEHFALDVKKRSDGSLVPELLLE 197
           +++++ E A PG RF L  A+D DVG NS+ SY+LS N +F+L ++ R+DG+  PEL+LE
Sbjct: 139 VEIKVSEHAIPGARFALPNARDPDVGVNSLQSYQLSPNNYFSLQLRGRTDGAKNPELVLE 198

Query: 198 KPLDREKQSDYRLVLTAVDGGNPPRSGTAELRVSVLDVNDNAPAFQQSSYRISVLESAPA 257
             LDREK++ + L+LTA+DGG+P R G   +RV VLDVND+ P F QS YR+SV E+  +
Sbjct: 199 GSLDREKEAAHLLLLTALDGGDPIRKGAVPIRVVVLDVNDHIPMFTQSVYRVSVPENISS 258

Query: 258 GMVLIQLNASDPDLGPSGNVTFYFSGHTPDRVRNLFSLHPTTGKLTLLGPLDFESENYYE 317
           G  ++ +NA+DPD G +G V + F  +   +   +F L   TG++ + G LDFE   +YE
Sbjct: 259 GTRVLMVNATDPDEGINGEVMYSFR-NMESKASEIFQLDSQTGEVQVRGSLDFEKYRFYE 317

Query: 318 FDVRARDGGSPAMEQHCSLRVDLLDVNDNAPYITVTSELGTLPESAEPGTVVALISVQDP 377
            +++ +DGG   +    ++ + ++DVNDNAP IT+TS + ++ E++ PGTV+AL++VQD 
Sbjct: 318 MEIQGQDGGG--LFTTTTMLITVVDVNDNAPEITITSSINSILENSPPGTVIALLNVQDQ 375

Query: 378 DSGSNGDVSLRIPDHLPFALKSAFRNQFSLVTAGPLDREAKSSYDIMVTASDAGNPPLST 437
           DSG NG VS  IP+HLPF L+  + N + L+T+  LDRE   SY+I +TA+D G+PPLS 
Sbjct: 376 DSGENGQVSCFIPNHLPFKLEKTYGNYYKLITSRVLDRELVQSYNITLTATDQGSPPLSA 435

Query: 438 HRTIFLNISDVNDNPPSFFQRSHEVFVPENNRPGDLLCSLAASDPDSGLNALISYSLLEP 497
              ++LN++D NDNPP F   S+  ++PENN  G  + S+ A DPDS  NAL++YSL + 
Sbjct: 436 ETHVWLNVADDNDNPPVFPHSSYSAYIPENNPRGASIFSVTALDPDSKQNALVTYSLTDD 495

Query: 498 RNRDVSASSFISLNPQTGAVHATRSFDYEQTQTLQFEVQARDRGNPPLSSTVTVRLFVLD 557
             + V  SS++S+N  TG ++A +SFDYEQ + L+  V ARD G+PPLSS V++ LFVLD
Sbjct: 496 TVQGVPLSSYVSINSNTGVLYALQSFDYEQFRDLELRVIARDSGDPPLSSNVSLSLFVLD 555

Query: 558 LNDNAPAVLRPR-ARPGSLCPQALPPSVGAGHLITKVTAVDLDSGYNAWVSYQLLEAPDP 616
            NDNAP +L P     GS   +  P S   G+L+TKV AVD DSG NAW+SY+LL+A +P
Sbjct: 556 QNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDKDSGQNAWLSYRLLKASEP 615

Query: 617 SLFAVSRYAGEVRTA-VPIPADLPPQKLVIVVKDSGSPPLSTSVTLLVSLEEDTHPVVPD 675
            LFAV  + GEVRTA   +  D   Q LV+ V+D G PPLS +VTL V++ +    V+ D
Sbjct: 616 GLFAVGEHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADSIPEVLAD 675

Query: 676 LRESSAPREGE-SRLTLYLAVSLVAICFVSFGSFVALLS 713
           L    +    E S L+LYL V++ A+  +     + LL+
Sbjct: 676 LGSLESLANSETSDLSLYLVVAVAAVSCIFLVFVIVLLA 714


>gi|14717401 protocadherin alpha subfamily C, 1 isoform 1 precursor
           [Homo sapiens]
          Length = 963

 Score =  590 bits (1522), Expect = e-168
 Identities = 371/954 (38%), Positives = 524/954 (54%), Gaps = 52/954 (5%)

Query: 17  LLFLFYHLGYVCGQIRYPVPEESQEGTFVGNVAQDFLLDTDSLSARRLQVAGEVNQRHFR 76
           +L L+   G   GQ+ Y VPEE++ G  VGN++ D  L   ++S+R  +      + +F 
Sbjct: 8   VLCLWVSCGAAAGQLEYSVPEETERGVAVGNLSADLRLPAAAMSSRNFRFLSSHRELYFG 67

Query: 77  VDLDSGALLIKNPIDREALCGLSASCIVPLEFVTEGPLEMYRAEVEIVDVNDHAPRFPRQ 136
           VDL SG L+++ P DRE LC   A+C++  + V E PLE+++  + ++D ND++P FP  
Sbjct: 68  VDLPSGNLVVREPADREQLCRAKAACVLTYDLVLEDPLELHKIRIHVLDTNDNSPLFPAG 127

Query: 137 QLDLEIGEAAPPGQRFPLEKAQDADVGSNSISSYRLSSNEHFALDVKKRSDGSLVPELLL 196
            + L I E   PG RF L  AQD D GSN I SY LS ++HF LD+  R DGS  PEL+L
Sbjct: 128 DVQLHIPEFLTPGARFTLPNAQDDDEGSNGILSYSLSPSQHFRLDMGSRVDGSEYPELVL 187

Query: 197 EKPLDREKQSDYRLVLTAVDGGNPPRSGTAELRVSVLDVNDNAPAFQQSSYRISVLESAP 256
           EK LDRE+++ + LVLTA DGG P RSG A++ + V+D NDNAP F++S YR  V E+AP
Sbjct: 188 EKALDREQRATHLLVLTARDGGLPARSGDAQVTIIVVDTNDNAPVFERSVYRTKVPETAP 247

Query: 257 AGMVLIQLNASDPDLGPSGNVTFYFSGHTPDRVRNLFSLHPTTGKLTL---LGPLDFESE 313
            G VL ++ A DPD G +G V +  S  T   +R+ F +HP +G++ +   LGP +   E
Sbjct: 248 NGTVLFRVQALDPDEGSNGEVQYSLSNSTQAELRHRFHVHPKSGEVQVAASLGPPETLLE 307

Query: 314 NYYEFDVRARDGGSPAMEQHCSLRVDLLDVNDNAPYITVTSELGTLPESAEPGTVVALIS 373
            Y E    ARD G   +     L V++ DVND+AP +   +    +PE A PGTV+AL S
Sbjct: 308 AYIE----ARDEGVFGLASTAKLLVEVTDVNDHAPELDFLTLSNPVPEDAAPGTVIALFS 363

Query: 374 VQDPDSGSNGDVSLRIPDHLPFALKSAFRNQFSLVTAGPLDREAKSSYDIMVTASDAGNP 433
           V+D D  SNG V   +    PF L ++F N +SL+  GPLDRE  S Y +++TASD+G+P
Sbjct: 364 VKDEDLDSNGRVICGMSSAGPFQLTASFDNYYSLLIDGPLDREQISEYQVLITASDSGSP 423

Query: 434 PLSTHRTIFLNISDVNDNPPSFFQRSHEVFVPENNRPGDLLCSLAASDPDSGLNALISYS 493
           PLST RTI ++++DVNDN P+F Q   E+FV ENN PG  L  + A DPD G N L+SY 
Sbjct: 424 PLSTRRTITVSVADVNDNTPNFPQPQQELFVAENNGPGASLGRVFAQDPDLGKNGLVSYE 483

Query: 494 LLEPRNRDVSASSFISLNPQTGAVHATRSFDYEQTQTLQFEVQARDRGNPPLSSTVTVRL 553
           LL+  +   SASS +++   +GA+ A  SFD+EQ +   F+V+ RD G PP S+TVT+ L
Sbjct: 484 LLDVISEGPSASSLLAVESSSGAITAKTSFDFEQLRGFHFQVEGRDGGIPPRSATVTINL 543

Query: 554 FVLDLNDNAPAVLRPRARPGSLCPQALPPSVGAGHLITKVTAVDLDSGYNAWVSYQLLEA 613
           FV+D NDN P +L P  R GS+  + +P S   GHL+TKV A D DSG NAW+SY +  A
Sbjct: 544 FVVDRNDNYPVILFPLPRNGSVPVEIVPRSARTGHLVTKVVAEDADSGSNAWLSYHISRA 603

Query: 614 PDPSLFAVSRYAGEVRTA-VPIPADLPPQKLVIVVKDSGSPPLSTSVTLLVSLEEDTHPV 672
            D SLF +S   GE+RTA + +P D   Q++V+VV+D G PPLS+SVTL V L      +
Sbjct: 604 SDSSLFRISANIGELRTARLVLPTDAVKQRVVVVVRDHGDPPLSSSVTLGVLLSNSVPQL 663

Query: 673 VPDLRESSAPREGESRLTLYLAVSLVAICFVSFGSFVALLSKCLRGAACGVTCFPAGTCA 732
           +PD  +   P    S   LYL ++L  I F+  G        CL    C       G CA
Sbjct: 664 LPDFEDVWEPGGQLSAQNLYLVIALACISFLFLG--------CLLFFVCTKLHQSPGCCA 715

Query: 733 CLTRSRRREGLPPSNGILRIQLGSDDPIKFVDVGGHSHGCTPLASAPTRSDSFMMVKSPS 792
             +  R  E L   + ++     +   I    V   S      AS    SD+  ++    
Sbjct: 716 -QSCCRSTEDLRYGSKMVSNPCMTSATIDVTTVERLSQTYLYRASLGLGSDNNSLLLRGE 774

Query: 793 ---------APMAGEPVRPSCPPSDLLYG----LEQAP--PNTDWRFSQAQRPGTSGSQN 837
                    A   G  +  SC       G    +   P  PN DWR+S + R G   S +
Sbjct: 775 YNAADLRNLATGVGLNLPISCIQIRNRKGDHANVNAMPRQPNPDWRYSASLRAGMHSSVH 834

Query: 838 GDDTGT------WPNNQFDTEMLQAMILASAS---EAADGSSTLGGGAGTMGLSARYGPQ 888
            ++ G        P+ Q+ T       ++SA+   EA + S  +G G  +   + +YGP 
Sbjct: 835 LEEAGILRAGPGGPDQQWPT-------VSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPG 887

Query: 889 FTLQHVP-DYRQNVYIPGSNATLT---NAAGKRDGKAPAGGNGNKKKSGKKEKK 938
              Q  P +      IPGS A ++        +  K+     G K+++ KK+KK
Sbjct: 888 NPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKKEETKKKKKK 941


>gi|14277677 protocadherin gamma subfamily C, 3 isoform 2 precursor
           [Homo sapiens]
          Length = 863

 Score =  588 bits (1515), Expect = e-167
 Identities = 305/685 (44%), Positives = 424/685 (61%), Gaps = 3/685 (0%)

Query: 17  LLFLFYHLGYVCGQIRYPVPEESQEGTFVGNVAQDFLLDTDSLSARRLQVAGEVNQRHFR 76
           +L L   L      I Y +PEE ++G  VGNV  +  LD  SLSARR +V    ++R F 
Sbjct: 19  VLLLLGALNKASTVIHYEIPEEREKGFAVGNVVANLGLDLGSLSARRFRVVSGASRRFFE 78

Query: 77  VDLDSGALLIKNPIDREALCGLSASCIVPLEFVTEGPLEMYRAEVEIVDVNDHAPRFPRQ 136
           V+ ++G + + + +DRE LCG   SC V LE V E PLE++  EV I D+ND+ P FP Q
Sbjct: 79  VNRETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFSVEVVIQDINDNNPAFPTQ 138

Query: 137 QLDLEIGEAAPPGQRFPLEKAQDADVGSNSISSYRLSSNEHFALDVKKRSDGSLVPELLL 196
           ++ LEI EA  PG RFPLE A D DVGSNS+ +Y LS NE+FAL V+ R D +   EL+L
Sbjct: 139 EMKLEISEAVAPGTRFPLESAHDPDVGSNSLQTYELSRNEYFALRVQTREDSTKYAELVL 198

Query: 197 EKPLDREKQSDYRLVLTAVDGGNPPRSGTAELRVSVLDVNDNAPAFQQSSYRISVLESAP 256
           E+ LDRE++   +LVLTA+DGG P  S +  + + VLD NDNAP F QS YR  VLE AP
Sbjct: 199 ERALDREREPSLQLVLTALDGGTPALSASLPIHIKVLDANDNAPVFNQSLYRARVLEDAP 258

Query: 257 AGMVLIQLNASDPDLGPSGNVTFYFSGHTPDRVRNLFSLHPTTGKLTLLGPLDFESENYY 316
           +G  ++Q+ A+D D GP+G + + F  H    VR LF+L   TG LT+ G LDFE    +
Sbjct: 259 SGTRVVQVLATDLDEGPNGEIIYSFGSHNRAGVRQLFALDLVTGMLTIKGRLDFEDTKLH 318

Query: 317 EFDVRARDGGSPAMEQHCSLRVDLLDVNDNAPYITVTSELGTLPESAEPGTVVALISVQD 376
           E  ++A+D G+     HC + V+++DVNDNAP ITVTS    +PE A  GTV+AL+SV D
Sbjct: 319 EIYIQAKDKGANPEGAHCKVLVEVVDVNDNAPEITVTSVYSPVPEDAPLGTVIALLSVTD 378

Query: 377 PDSGSNGDVSLRIPDHLPFALKSAFRNQFSLVTAGPLDREAKSSYDIMVTASDAGNPPLS 436
            D+G NG V+  +P  LPF+L S+ +N F+L T+  LDRE    Y++ +TA DAG P LS
Sbjct: 379 LDAGENGLVTCEVPPGLPFSLTSSLKNYFTLKTSADLDRETVPEYNLSITARDAGTPSLS 438

Query: 437 THRTIFLNISDVNDNPPSFFQRSHEVFVPENNRPGDLLCSLAASDPDSGLNALISYSLLE 496
               + + +SD+NDNPP   Q S++V++ ENN PG  + +L+  DPD+  NA +S+ LLE
Sbjct: 439 ALTIVRVQVSDINDNPPQSSQSSYDVYIEENNLPGAPILNLSVWDPDAPQNARLSFFLLE 498

Query: 497 PRNRDVSASSFISLNPQTGAVHATRSFDYEQTQTLQFEVQARDRGNPPLSSTVTVRLFVL 556
                     + ++N   G V +    DYE  +  +      D G P L++ ++V +FV 
Sbjct: 499 QGAETGLVGRYFTINRDNGIVSSLVPLDYEDRREFELTAHISDGGTPVLATNISVNIFVT 558

Query: 557 DLNDNAPAVLRPRARPGSLCPQALPPSVGAGHLITKVTAVDLDSGYNAWVSYQLLEAPDP 616
           D NDNAP VL P  RPG    + LP    AGHL+++V   D D+G+NAW+SY LL +P+ 
Sbjct: 559 DRNDNAPQVLYP--RPGGSSVEMLPRGTSAGHLVSRVVGWDADAGHNAWLSYSLLGSPNQ 616

Query: 617 SLFAVSRYAGEVRTAVPI-PADLPPQKLVIVVKDSGSPPLSTSVTLLVSLEEDTHPVVPD 675
           SLFA+  + G++ TA P+   D P Q L +++KD+G P LST+ TL VS+ ED+     +
Sbjct: 617 SLFAIGLHTGQISTARPVQDTDSPRQTLTVLIKDNGEPSLSTTATLTVSVTEDSPEARAE 676

Query: 676 LRESSAPREGESRLTLYLAVSLVAI 700
               SAPRE +  LT YL +SL+ +
Sbjct: 677 FPSGSAPREQKKNLTFYLLLSLILV 701


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.134    0.395 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 39,429,724
Number of Sequences: 37866
Number of extensions: 1925518
Number of successful extensions: 12286
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 192
Number of HSP's successfully gapped in prelim test: 33
Number of HSP's that attempted gapping in prelim test: 5006
Number of HSP's gapped (non-prelim): 750
length of query: 938
length of database: 18,247,518
effective HSP length: 112
effective length of query: 826
effective length of database: 14,006,526
effective search space: 11569390476
effective search space used: 11569390476
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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