Guide to the Human Genome
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Search of human proteins with 11128023

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|11128023 protocadherin gamma subfamily C, 5 isoform 1
precursor [Homo sapiens]
         (944 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|11128023 protocadherin gamma subfamily C, 5 isoform 1 precurs...  1887   0.0  
gi|14277685 protocadherin gamma subfamily C, 5 isoform 2 precurs...  1634   0.0  
gi|11128025 protocadherin gamma subfamily C, 4 isoform 1 precurs...   926   0.0  
gi|11128039 protocadherin gamma subfamily A, 11 isoform 1 precur...   856   0.0  
gi|11056024 protocadherin gamma subfamily A, 5 isoform 1 precurs...   855   0.0  
gi|11056026 protocadherin gamma subfamily A, 4 isoform 1 precurs...   854   0.0  
gi|14589880 protocadherin gamma subfamily A, 3 isoform 1 precurs...   851   0.0  
gi|11128037 protocadherin gamma subfamily B, 1 isoform 1 precurs...   846   0.0  
gi|11056030 protocadherin gamma subfamily A, 2 isoform 1 precurs...   840   0.0  
gi|8850232 protocadherin gamma subfamily A, 12 isoform 1 precurs...   839   0.0  
gi|11056065 protocadherin gamma subfamily A, 6 isoform 1 precurs...   839   0.0  
gi|11128043 protocadherin gamma subfamily A, 9 isoform 1 precurs...   838   0.0  
gi|14270484 protocadherin gamma subfamily A, 8 isoform 1 precurs...   833   0.0  
gi|11056063 protocadherin gamma subfamily A, 7 isoform 1 precurs...   831   0.0  
gi|11128041 protocadherin gamma subfamily A, 10 isoform 1 precur...   830   0.0  
gi|11128027 protocadherin gamma subfamily B, 7 isoform 1 precurs...   828   0.0  
gi|13470082 protocadherin gamma subfamily B, 4 isoform 1 precurs...   821   0.0  
gi|11128029 protocadherin gamma subfamily B, 6 isoform 1 precurs...   815   0.0  
gi|11128031 protocadherin gamma subfamily B, 5 isoform 1 precurs...   814   0.0  
gi|14277675 protocadherin gamma subfamily C, 3 isoform 1 precurs...   812   0.0  
gi|11128035 protocadherin gamma subfamily B, 2 isoform 1 precurs...   811   0.0  
gi|11056032 protocadherin gamma subfamily A, 1 isoform 1 precurs...   811   0.0  
gi|11128033 protocadherin gamma subfamily B, 3 isoform 1 precurs...   809   0.0  
gi|9256600 protocadherin alpha subfamily C, 2 isoform 1 precurso...   689   0.0  
gi|14277682 protocadherin gamma subfamily C, 4 isoform 2 precurs...   678   0.0  
gi|14165431 protocadherin alpha subfamily C, 2 isoform 2 precurs...   664   0.0  
gi|14589916 protocadherin 10 isoform 1 precursor [Homo sapiens]       635   0.0  
gi|14589914 protocadherin 10 isoform 2 precursor [Homo sapiens]       629   e-180
gi|9256586 protocadherin alpha 3 isoform 1 precursor [Homo sapiens]   621   e-177
gi|9256596 protocadherin alpha 8 isoform 1 precursor [Homo sapiens]   614   e-175

>gi|11128023 protocadherin gamma subfamily C, 5 isoform 1 precursor
           [Homo sapiens]
          Length = 944

 Score = 1887 bits (4887), Expect = 0.0
 Identities = 944/944 (100%), Positives = 944/944 (100%)

Query: 1   MGPKTLPQLAGKWQVLCMLSLCCWGWVSGQLRYSVVEESEPGTLVGNVAQDLGLKMTDLL 60
           MGPKTLPQLAGKWQVLCMLSLCCWGWVSGQLRYSVVEESEPGTLVGNVAQDLGLKMTDLL
Sbjct: 1   MGPKTLPQLAGKWQVLCMLSLCCWGWVSGQLRYSVVEESEPGTLVGNVAQDLGLKMTDLL 60

Query: 61  SRRLQLGSEENGRYFSLSLMSGALAVNQKIDRESLCGASTSCLLPVQVVTEHPLELIRVE 120
           SRRLQLGSEENGRYFSLSLMSGALAVNQKIDRESLCGASTSCLLPVQVVTEHPLELIRVE
Sbjct: 61  SRRLQLGSEENGRYFSLSLMSGALAVNQKIDRESLCGASTSCLLPVQVVTEHPLELIRVE 120

Query: 121 VEILDLNDNSPSFATPEREMRISESAASGARFPLDSAQDPDVGTNTVSFYTLSPNSHFSL 180
           VEILDLNDNSPSFATPEREMRISESAASGARFPLDSAQDPDVGTNTVSFYTLSPNSHFSL
Sbjct: 121 VEILDLNDNSPSFATPEREMRISESAASGARFPLDSAQDPDVGTNTVSFYTLSPNSHFSL 180

Query: 181 NVKTLKDGKPFPELVLEQQLDREAQARHQLVLTAVDGGTPARSGTTLISVIVLDINDNAP 240
           NVKTLKDGKPFPELVLEQQLDREAQARHQLVLTAVDGGTPARSGTTLISVIVLDINDNAP
Sbjct: 181 NVKTLKDGKPFPELVLEQQLDREAQARHQLVLTAVDGGTPARSGTTLISVIVLDINDNAP 240

Query: 241 TFQSSVLRVGIPENAPIGTLLLRLNATDPDEGTNGQLDYSFGDHTSEAVRNLFGLDPSSG 300
           TFQSSVLRVGIPENAPIGTLLLRLNATDPDEGTNGQLDYSFGDHTSEAVRNLFGLDPSSG
Sbjct: 241 TFQSSVLRVGIPENAPIGTLLLRLNATDPDEGTNGQLDYSFGDHTSEAVRNLFGLDPSSG 300

Query: 301 AIHVLGPIDFEESRFYEIHARARDQGQPAMEGHCVIQVDVGDVNDNAPEVLLASLANPVL 360
           AIHVLGPIDFEESRFYEIHARARDQGQPAMEGHCVIQVDVGDVNDNAPEVLLASLANPVL
Sbjct: 301 AIHVLGPIDFEESRFYEIHARARDQGQPAMEGHCVIQVDVGDVNDNAPEVLLASLANPVL 360

Query: 361 ESTPVGTVVGLFNVRDRDSGRNGEVSLDISPDLPFQIKPSENHYSLLTSQPLDREATSHY 420
           ESTPVGTVVGLFNVRDRDSGRNGEVSLDISPDLPFQIKPSENHYSLLTSQPLDREATSHY
Sbjct: 361 ESTPVGTVVGLFNVRDRDSGRNGEVSLDISPDLPFQIKPSENHYSLLTSQPLDREATSHY 420

Query: 421 IIELLASDAGSPSLHKHLTIRLNISDVNDNAPRFNQQLYTAYILENRPPGSLLCTVAASD 480
           IIELLASDAGSPSLHKHLTIRLNISDVNDNAPRFNQQLYTAYILENRPPGSLLCTVAASD
Sbjct: 421 IIELLASDAGSPSLHKHLTIRLNISDVNDNAPRFNQQLYTAYILENRPPGSLLCTVAASD 480

Query: 481 PDTGDNARLTYSIVGNQVQGAPASSFVYVNPEDGRIFAQRTFDYELLQMLQIVVGVRDSG 540
           PDTGDNARLTYSIVGNQVQGAPASSFVYVNPEDGRIFAQRTFDYELLQMLQIVVGVRDSG
Sbjct: 481 PDTGDNARLTYSIVGNQVQGAPASSFVYVNPEDGRIFAQRTFDYELLQMLQIVVGVRDSG 540

Query: 541 SPPLHANTSLHVFVLDENDNAPAVLHPRPDWEHSAPQRLPRSAPPGSLVTKVTAVDADAG 600
           SPPLHANTSLHVFVLDENDNAPAVLHPRPDWEHSAPQRLPRSAPPGSLVTKVTAVDADAG
Sbjct: 541 SPPLHANTSLHVFVLDENDNAPAVLHPRPDWEHSAPQRLPRSAPPGSLVTKVTAVDADAG 600

Query: 601 HNAWLSYSLLPQSTAPGLFLVSTHTGEVRTARALLEDDSDTQQVVVLVRDNGDPSLSSTA 660
           HNAWLSYSLLPQSTAPGLFLVSTHTGEVRTARALLEDDSDTQQVVVLVRDNGDPSLSSTA
Sbjct: 601 HNAWLSYSLLPQSTAPGLFLVSTHTGEVRTARALLEDDSDTQQVVVLVRDNGDPSLSSTA 660

Query: 661 TVLLVLEDEDPEEMPKSSDFLIHPPERSDLTLYLIVALATVSLLSLVTFTFLSAKCLQGN 720
           TVLLVLEDEDPEEMPKSSDFLIHPPERSDLTLYLIVALATVSLLSLVTFTFLSAKCLQGN
Sbjct: 661 TVLLVLEDEDPEEMPKSSDFLIHPPERSDLTLYLIVALATVSLLSLVTFTFLSAKCLQGN 720

Query: 721 ADGDGGGGQCCRRQDSPSPDFYKQSSPNLQVSSDGTLKYMEVTLRPTDSQSHCYRTCFSP 780
           ADGDGGGGQCCRRQDSPSPDFYKQSSPNLQVSSDGTLKYMEVTLRPTDSQSHCYRTCFSP
Sbjct: 721 ADGDGGGGQCCRRQDSPSPDFYKQSSPNLQVSSDGTLKYMEVTLRPTDSQSHCYRTCFSP 780

Query: 781 ASDGSDFTFLRPLSVQQPTALALEPDAIRSRSNTLRERSQQAPPNTDWRFSQAQRPGTSG 840
           ASDGSDFTFLRPLSVQQPTALALEPDAIRSRSNTLRERSQQAPPNTDWRFSQAQRPGTSG
Sbjct: 781 ASDGSDFTFLRPLSVQQPTALALEPDAIRSRSNTLRERSQQAPPNTDWRFSQAQRPGTSG 840

Query: 841 SQNGDDTGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHV 900
           SQNGDDTGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHV
Sbjct: 841 SQNGDDTGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHV 900

Query: 901 PDYRQNVYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK 944
           PDYRQNVYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK
Sbjct: 901 PDYRQNVYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK 944


>gi|14277685 protocadherin gamma subfamily C, 5 isoform 2 precursor
           [Homo sapiens]
          Length = 878

 Score = 1634 bits (4231), Expect = 0.0
 Identities = 823/827 (99%), Positives = 823/827 (99%), Gaps = 3/827 (0%)

Query: 1   MGPKTLPQLAGKWQVLCMLSLCCWGWVSGQLRYSVVEESEPGTLVGNVAQDLGLKMTDLL 60
           MGPKTLPQLAGKWQVLCMLSLCCWGWVSGQLRYSVVEESEPGTLVGNVAQDLGLKMTDLL
Sbjct: 1   MGPKTLPQLAGKWQVLCMLSLCCWGWVSGQLRYSVVEESEPGTLVGNVAQDLGLKMTDLL 60

Query: 61  SRRLQLGSEENGRYFSLSLMSGALAVNQKIDRESLCGASTSCLLPVQVVTEHPLELIRVE 120
           SRRLQLGSEENGRYFSLSLMSGALAVNQKIDRESLCGASTSCLLPVQVVTEHPLELIRVE
Sbjct: 61  SRRLQLGSEENGRYFSLSLMSGALAVNQKIDRESLCGASTSCLLPVQVVTEHPLELIRVE 120

Query: 121 VEILDLNDNSPSFATPEREMRISESAASGARFPLDSAQDPDVGTNTVSFYTLSPNSHFSL 180
           VEILDLNDNSPSFATPEREMRISESAASGARFPLDSAQDPDVGTNTVSFYTLSPNSHFSL
Sbjct: 121 VEILDLNDNSPSFATPEREMRISESAASGARFPLDSAQDPDVGTNTVSFYTLSPNSHFSL 180

Query: 181 NVKTLKDGKPFPELVLEQQLDREAQARHQLVLTAVDGGTPARSGTTLISVIVLDINDNAP 240
           NVKTLKDGKPFPELVLEQQLDREAQARHQLVLTAVDGGTPARSGTTLISVIVLDINDNAP
Sbjct: 181 NVKTLKDGKPFPELVLEQQLDREAQARHQLVLTAVDGGTPARSGTTLISVIVLDINDNAP 240

Query: 241 TFQSSVLRVGIPENAPIGTLLLRLNATDPDEGTNGQLDYSFGDHTSEAVRNLFGLDPSSG 300
           TFQSSVLRVGIPENAPIGTLLLRLNATDPDEGTNGQLDYSFGDHTSEAVRNLFGLDPSSG
Sbjct: 241 TFQSSVLRVGIPENAPIGTLLLRLNATDPDEGTNGQLDYSFGDHTSEAVRNLFGLDPSSG 300

Query: 301 AIHVLGPIDFEESRFYEIHARARDQGQPAMEGHCVIQVDVGDVNDNAPEVLLASLANPVL 360
           AIHVLGPIDFEESRFYEIHARARDQGQPAMEGHCVIQVDVGDVNDNAPEVLLASLANPVL
Sbjct: 301 AIHVLGPIDFEESRFYEIHARARDQGQPAMEGHCVIQVDVGDVNDNAPEVLLASLANPVL 360

Query: 361 ESTPVGTVVGLFNVRDRDSGRNGEVSLDISPDLPFQIKPSENHYSLLTSQPLDREATSHY 420
           ESTPVGTVVGLFNVRDRDSGRNGEVSLDISPDLPFQIKPSENHYSLLTSQPLDREATSHY
Sbjct: 361 ESTPVGTVVGLFNVRDRDSGRNGEVSLDISPDLPFQIKPSENHYSLLTSQPLDREATSHY 420

Query: 421 IIELLASDAGSPSLHKHLTIRLNISDVNDNAPRFNQQLYTAYILENRPPGSLLCTVAASD 480
           IIELLASDAGSPSLHKHLTIRLNISDVNDNAPRFNQQLYTAYILENRPPGSLLCTVAASD
Sbjct: 421 IIELLASDAGSPSLHKHLTIRLNISDVNDNAPRFNQQLYTAYILENRPPGSLLCTVAASD 480

Query: 481 PDTGDNARLTYSIVGNQVQGAPASSFVYVNPEDGRIFAQRTFDYELLQMLQIVVGVRDSG 540
           PDTGDNARLTYSIVGNQVQGAPASSFVYVNPEDGRIFAQRTFDYELLQMLQIVVGVRDSG
Sbjct: 481 PDTGDNARLTYSIVGNQVQGAPASSFVYVNPEDGRIFAQRTFDYELLQMLQIVVGVRDSG 540

Query: 541 SPPLHANTSLHVFVLDENDNAPAVLHPRPDWEHSAPQRLPRSAPPGSLVTKVTAVDADAG 600
           SPPLHANTSLHVFVLDENDNAPAVLHPRPDWEHSAPQRLPRSAPPGSLVTKVTAVDADAG
Sbjct: 541 SPPLHANTSLHVFVLDENDNAPAVLHPRPDWEHSAPQRLPRSAPPGSLVTKVTAVDADAG 600

Query: 601 HNAWLSYSLLPQSTAPGLFLVSTHTGEVRTARALLEDDSDTQQVVVLVRDNGDPSLSSTA 660
           HNAWLSYSLLPQSTAPGLFLVSTHTGEVRTARALLEDDSDTQQVVVLVRDNGDPSLSSTA
Sbjct: 601 HNAWLSYSLLPQSTAPGLFLVSTHTGEVRTARALLEDDSDTQQVVVLVRDNGDPSLSSTA 660

Query: 661 TVLLVLEDEDPEEMPKSSDFLIHPPERSDLTLYLIVALATVSLLSLVTFTFLSAKCLQGN 720
           TVLLVLEDEDPEEMPKSSDFLIHPPERSDLTLYLIVALATVSLLSLVTFTFLSAKCLQGN
Sbjct: 661 TVLLVLEDEDPEEMPKSSDFLIHPPERSDLTLYLIVALATVSLLSLVTFTFLSAKCLQGN 720

Query: 721 ADGDGGGGQCCRRQDSPSPDFYKQSSPNLQVSSDGTLKYMEVTLRPTDSQSHCYRTCFSP 780
           ADGDGGGGQCCRRQDSPSPDFYKQSSPNLQVSSDGTLKYMEVTLRPTDSQSHCYRTCFSP
Sbjct: 721 ADGDGGGGQCCRRQDSPSPDFYKQSSPNLQVSSDGTLKYMEVTLRPTDSQSHCYRTCFSP 780

Query: 781 ASDGSDFTFLRPLSVQQPTALALEPDAIRSRSNTLRERSQ---QAPP 824
           ASDGSDFTFLRPLSVQQPTALALEPDAIRSRSNTLRERSQ    APP
Sbjct: 781 ASDGSDFTFLRPLSVQQPTALALEPDAIRSRSNTLRERSQVRGSAPP 827


>gi|11128025 protocadherin gamma subfamily C, 4 isoform 1 precursor
           [Homo sapiens]
          Length = 938

 Score =  926 bits (2392), Expect = 0.0
 Identities = 500/929 (53%), Positives = 634/929 (68%), Gaps = 24/929 (2%)

Query: 25  GWVSGQLRYSVVEESEPGTLVGNVAQDLGLKMTDLLSRRLQLGSEENGRYFSLSLMSGAL 84
           G+V GQ+RY V EES+ GT VGNVAQD  L    L +RRLQ+  E N R+F + L SGAL
Sbjct: 25  GYVCGQIRYPVPEESQEGTFVGNVAQDFLLDTDSLSARRLQVAGEVNQRHFRVDLDSGAL 84

Query: 85  AVNQKIDRESLCGASTSCLLPVQVVTEHPLELIRVEVEILDLNDNSPSFATPEREMRISE 144
            +   IDRE+LCG S SC++P++ VTE PLE+ R EVEI+D+ND++P F   + ++ I E
Sbjct: 85  LIKNPIDREALCGLSASCIVPLEFVTEGPLEMYRAEVEIVDVNDHAPRFPRQQLDLEIGE 144

Query: 145 SAASGARFPLDSAQDPDVGTNTVSFYTLSPNSHFSLNVKTLKDGKPFPELVLEQQLDREA 204
           +A  G RFPL+ AQD DVG+N++S Y LS N HF+L+VK   DG   PEL+LE+ LDRE 
Sbjct: 145 AAPPGQRFPLEKAQDADVGSNSISSYRLSSNEHFALDVKKRSDGSLVPELLLEKPLDREK 204

Query: 205 QARHQLVLTAVDGGTPARSGTTLISVIVLDINDNAPTFQSSVLRVGIPENAPIGTLLLRL 264
           Q+ ++LVLTAVDGG P RSGT  + V VLD+NDNAP FQ S  R+ + E+AP G +L++L
Sbjct: 205 QSDYRLVLTAVDGGNPPRSGTAELRVSVLDVNDNAPAFQQSSYRISVLESAPAGMVLIQL 264

Query: 265 NATDPDEGTNGQLDYSFGDHTSEAVRNLFGLDPSSGAIHVLGPIDFEESRFYEIHARARD 324
           NA+DPD G +G + + F  HT + VRNLF L P++G + +LGP+DFE   +YE   RARD
Sbjct: 265 NASDPDLGPSGNVTFYFSGHTPDRVRNLFSLHPTTGKLTLLGPLDFESENYYEFDVRARD 324

Query: 325 QGQPAMEGHCVIQVDVGDVNDNAPEVLLASLANPVLESTPVGTVVGLFNVRDRDSGRNGE 384
            G PAME HC ++VD+ DVNDNAP + + S    + ES   GTVV L +V+D DSG NG+
Sbjct: 325 GGSPAMEQHCSLRVDLLDVNDNAPYITVTSELGTLPESAEPGTVVALISVQDPDSGSNGD 384

Query: 385 VSLDISPDLPFQIKPS-ENHYSLLTSQPLDREATSHYIIELLASDAGSPSLHKHLTIRLN 443
           VSL I   LPF +K +  N +SL+T+ PLDREA S Y I + ASDAG+P L  H TI LN
Sbjct: 385 VSLRIPDHLPFALKSAFRNQFSLVTAGPLDREAKSSYDIMVTASDAGNPPLSTHRTIFLN 444

Query: 444 ISDVNDNAPRFNQQLYTAYILENRPPGSLLCTVAASDPDTGDNARLTYSIVGNQVQGAPA 503
           ISDVNDN P F Q+ +  ++ EN  PG LLC++AASDPD+G NA ++YS++  + +   A
Sbjct: 445 ISDVNDNPPSFFQRSHEVFVPENNRPGDLLCSLAASDPDSGLNALISYSLLEPRNRDVSA 504

Query: 504 SSFVYVNPEDGRIFAQRTFDYELLQMLQIVVGVRDSGSPPLHANTSLHVFVLDENDNAPA 563
           SSF+ +NP+ G + A R+FDYE  Q LQ  V  RD G+PPL +  ++ +FVLD NDNAPA
Sbjct: 505 SSFISLNPQTGAVHATRSFDYEQTQTLQFEVQARDRGNPPLSSTVTVRLFVLDLNDNAPA 564

Query: 564 VLHPRPDWEHSAPQRLPRSAPPGSLVTKVTAVDADAGHNAWLSYSLLPQSTAPGLFLVST 623
           VL PR       PQ LP S   G L+TKVTAVD D+G+NAW+SY LL ++  P LF VS 
Sbjct: 565 VLRPRARPGSLCPQALPPSVGAGHLITKVTAVDLDSGYNAWVSYQLL-EAPDPSLFAVSR 623

Query: 624 HTGEVRTARALLEDDSDTQQVVVLVRDNGDPSLSSTATVLLVLEDEDPEEMPKSSDFLIH 683
           + GEVRTA   +  D   Q++V++V+D+G P LS++ T+L+ LE++    +P   +    
Sbjct: 624 YAGEVRTA-VPIPADLPPQKLVIVVKDSGSPPLSTSVTLLVSLEEDTHPVVPDLRESSAP 682

Query: 684 PPERSDLTLYLIVALATVSLLSLVTFTFLSAKCLQGNADG----DGGGGQC---CRRQDS 736
               S LTLYL V+L  +  +S  +F  L +KCL+G A G      G   C    RR++ 
Sbjct: 683 REGESRLTLYLAVSLVAICFVSFGSFVALLSKCLRGAACGVTCFPAGTCACLTRSRRREG 742

Query: 737 PSPDFYKQSSPNLQVSSDGTLKYMEVTLRPTDSQSHCYRTCFSPASDGSDFTFLRPLSVQ 796
             P         +Q+ SD  +K+++V        SH      S  +    F     + V+
Sbjct: 743 LPP---SNGILRIQLGSDDPIKFVDV-----GGHSHGCTPLASAPTRSDSF-----MMVK 789

Query: 797 QPTA-LALEPDAIRSRSNTLRERSQQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQF 855
            P+A +A EP       + L    +QAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQF
Sbjct: 790 SPSAPMAGEPVRPSCPPSDLLYGLEQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQF 849

Query: 856 DTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNAT 915
           DTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNAT
Sbjct: 850 DTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNAT 909

Query: 916 LTNAAGKRDGKAPAGGNGNKKKSGKKEKK 944
           LTNAAGKRDGKAPAGGNGNKKKSGKKEKK
Sbjct: 910 LTNAAGKRDGKAPAGGNGNKKKSGKKEKK 938


>gi|11128039 protocadherin gamma subfamily A, 11 isoform 1 precursor
           [Homo sapiens]
          Length = 935

 Score =  856 bits (2211), Expect = 0.0
 Identities = 479/947 (50%), Positives = 619/947 (65%), Gaps = 44/947 (4%)

Query: 15  VLCMLSLCCWGWVSGQLRYSVVEESEPGTLVGNVAQDLGLKMTDLLSRRLQLGSEENGRY 74
           +LC+      G+ + Q+RYSV EE+E G+ VGN+++DLGL+  +L  R +++ S    + 
Sbjct: 16  LLCIFLGTLRGFRARQIRYSVPEETEKGSFVGNISKDLGLEPRELAKRGVRIVSRGKTQL 75

Query: 75  FSLSLMSGALAVNQKIDRESLCGASTSCLLPVQVVTEHPLELIRVEVEILDLNDNSPSFA 134
           F+++  SG+L    +IDRE LC   +SC L ++++ E  L++  VEVEI+D+NDN+PSF 
Sbjct: 76  FAVNPRSGSLITAGRIDREELCETVSSCFLNMELLVEDTLKIYGVEVEIIDINDNAPSFQ 135

Query: 135 TPEREMRISESAASGARFPLDSAQDPDVGTNTVSFYTLSPNSHFSLNVKTLKDGKPFPEL 194
             E E+++SE A  GARF L +A+DPDVG N++  Y LSPN++FSL ++   DG   PEL
Sbjct: 136 EDEVEIKVSEHAIPGARFALPNARDPDVGVNSLQSYQLSPNNYFSLQLRGRTDGAKNPEL 195

Query: 195 VLEQQLDREAQARHQLVLTAVDGGTPARSGTTLISVIVLDINDNAPTFQSSVLRVGIPEN 254
           VLE  LDRE +A H L+LTA+DGG P R G   I V+VLD+ND+ P F  SV RV +PEN
Sbjct: 196 VLEGSLDREKEAAHLLLLTALDGGDPIRKGAVPIRVVVLDVNDHIPMFTQSVYRVSVPEN 255

Query: 255 APIGTLLLRLNATDPDEGTNGQLDYSFGDHTSEAVRNLFGLDPSSGAIHVLGPIDFEESR 314
              GT +L +NATDPDEG NG++ YSF +  S+A   +F LD  +G + V G +DFE+ R
Sbjct: 256 ISSGTRVLMVNATDPDEGINGEVMYSFRNMESKA-SEIFQLDSQTGEVQVRGSLDFEKYR 314

Query: 315 FYEIHARARDQGQPAMEGHCVIQVDVGDVNDNAPEVLLASLANPVLESTPVGTVVGLFNV 374
           FYE+  + +D G   +     + + V DVNDNAPE+ + S  N +LE++P GTV+ L NV
Sbjct: 315 FYEMEIQGQDGG--GLFTTTTMLITVVDVNDNAPEITITSSINSILENSPPGTVIALLNV 372

Query: 375 RDRDSGRNGEVSLDISPDLPFQI-KPSENHYSLLTSQPLDREATSHYIIELLASDAGSPS 433
           +D+DSG NG+VS  I   LPF++ K   N+Y L+TS+ LDRE    Y I L A+D GSP 
Sbjct: 373 QDQDSGENGQVSCFIPNHLPFKLEKTYGNYYKLITSRVLDRELVQSYNITLTATDQGSPP 432

Query: 434 LHKHLTIRLNISDVNDNAPRFNQQLYTAYILENRPPGSLLCTVAASDPDTGDNARLTYSI 493
           L     + LN++D NDN P F    Y+AYI EN P G+ + +V A DPD+  NA +TYS+
Sbjct: 433 LSAETHVWLNVADDNDNPPVFPHSSYSAYIPENNPRGASIFSVTALDPDSKQNALVTYSL 492

Query: 494 VGNQVQGAPASSFVYVNPEDGRIFAQRTFDYELLQMLQIVVGVRDSGSPPLHANTSLHVF 553
             + VQG P SS+V +N   G ++A ++FDYE  + L++ V  RDSG PPL +N SL +F
Sbjct: 493 TDDTVQGVPLSSYVSINSNTGVLYALQSFDYEQFRDLELRVIARDSGDPPLSSNVSLSLF 552

Query: 554 VLDENDNAPAVLHPRPDWEHSAPQRL-PRSAPPGSLVTKVTAVDADAGHNAWLSYSLLPQ 612
           VLD+NDNAP +L+P    + S    L PRSA PG LVTKV AVD D+G NAWLSY LL +
Sbjct: 553 VLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDKDSGQNAWLSYRLL-K 611

Query: 613 STAPGLFLVSTHTGEVRTARALLEDDSDTQQVVVLVRDNGDPSLSSTATVLLVLEDEDPE 672
           ++ PGLF V  HTGEVRTARALL+ D+  Q +VV V+D+G P LS+T T+ + + D  PE
Sbjct: 612 ASEPGLFAVGEHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADSIPE 671

Query: 673 EMPKSSDF-LIHPPERSDLTLYLIVALATVSLLSLVTFTFLSA---------KCLQGNAD 722
            +        +   E SDL+LYL+VA+A VS + LV    L A         + LQ +  
Sbjct: 672 VLADLGSLESLANSETSDLSLYLVVAVAAVSCIFLVFVIVLLALRLWRWHKSRLLQASEG 731

Query: 723 GDGGGGQCCRRQDSPSPDFYKQSSPNLQVSSDGTLKYM-----EVTLRPTDSQSHCYRTC 777
           G  G          P+  F         V  DG   ++     EV+L     +SH     
Sbjct: 732 GLAG---------MPTSHF---------VGVDGVQAFLQTYSHEVSLIADSQKSHLI--- 770

Query: 778 FSPASDGSDFTFLRPLSVQQPTALALEPDAIRSRSNTLRERSQQAPPNTDWRFSQAQRPG 837
           F   + G            +P  +A +   I  + +     +QQAPPNTDWRFSQAQRPG
Sbjct: 771 FPQPNYGDTLISQESCEKSEPLLIAEDSAIILGKCDPTS--NQQAPPNTDWRFSQAQRPG 828

Query: 838 TSGSQNGDDTGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTL 897
           TSGSQNGDDTGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTL
Sbjct: 829 TSGSQNGDDTGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTL 888

Query: 898 QHVPDYRQNVYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK 944
           QHVPDYRQNVYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK
Sbjct: 889 QHVPDYRQNVYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK 935


>gi|11056024 protocadherin gamma subfamily A, 5 isoform 1 precursor
           [Homo sapiens]
          Length = 931

 Score =  855 bits (2208), Expect = 0.0
 Identities = 481/925 (52%), Positives = 607/925 (65%), Gaps = 29/925 (3%)

Query: 28  SGQLRYSVVEESEPGTLVGNVAQDLGLKMTDLLSRRLQLGSEENGRYFSLSLMSGALAVN 87
           SGQ+RYS+ EE + G+ VGN+A+DLGL+  +L  R +++ S    + F+L+  SG+L   
Sbjct: 28  SGQIRYSMPEELDKGSFVGNIAKDLGLEPQELAERGVRIVSRGRTQLFALNPRSGSLVTA 87

Query: 88  QKIDRESLCGASTSCLLPVQVVTEHPLELIRVEVEILDLNDNSPSFATPEREMRISESAA 147
            +IDRE LC  S  C++   ++ E+ +++  VEVEI+D+NDN P F   E +++++E+AA
Sbjct: 88  GRIDREELCAQSPLCVVNFNILVENKMKIYGVEVEIIDINDNFPRFRDEELKVKVNENAA 147

Query: 148 SGARFPLDSAQDPDVGTNTVSFYTLSPNSHFSLNVKTLKDGKPFPELVLEQQLDREAQAR 207
           +G R  L  A+D DVG N++  Y LS N HFSL+V +  DG+ +PELVLEQ LDRE +  
Sbjct: 148 AGTRLVLPFARDADVGVNSLRSYQLSSNLHFSLDVVSGTDGQKYPELVLEQPLDREKETV 207

Query: 208 HQLVLTAVDGGTPARSGTTLISVIVLDINDNAPTFQSSVLRVGIPENAPIGTLLLRLNAT 267
           H L+LTA+DGG P  SGTT I V VLD NDNAP F  S   V +PEN P+GT LL L AT
Sbjct: 208 HDLLLTALDGGDPVLSGTTHIRVTVLDANDNAPLFTPSEYSVSVPENIPVGTRLLMLTAT 267

Query: 268 DPDEGTNGQLDYSFGDHTSEAVRNLFGLDPSSGAIHVLGPIDFEESRFYEIHARARDQGQ 327
           DPDEG NG+L YSF +   E +   F LD + G I  L  +D+EESRFY +   A+D G 
Sbjct: 268 DPDEGINGKLTYSFRNE-EEKISETFQLDSNLGEISTLQSLDYEESRFYLMEVVAQDGG- 325

Query: 328 PAMEGHCVIQVDVGDVNDNAPEVLLASLANPVLESTPVGTVVGLFNVRDRDSGRNGEVSL 387
            A+     + V V DVNDNAPEV+L SL + + E    GTV+ LF+V D DSG NGE++ 
Sbjct: 326 -ALVASAKVVVTVQDVNDNAPEVILTSLTSSISEDCLPGTVIALFSVHDGDSGENGEIAC 384

Query: 388 DISPDLPFQIKPS-ENHYSLLTSQPLDREATSHYIIELLASDAGSPSLHKHLTIRLNISD 446
            I  +LPF+++ S +N+Y LLT++ LDRE TS Y I L   D G+P L     I L ++D
Sbjct: 385 SIPRNLPFKLEKSVDNYYHLLTTRDLDREETSDYNITLTVMDHGTPPLSTESHIPLKVAD 444

Query: 447 VNDNAPRFNQQLYTAYILENRPPGSLLCTVAASDPDTGDNARLTYSIVGNQVQGAPASSF 506
           VNDN P F Q  Y+  + EN P G  + +V A DPD+GDNAR+TYS+  +  QGAP SS+
Sbjct: 445 VNDNPPNFPQASYSTSVTENNPRGVSIFSVTAHDPDSGDNARVTYSLAEDTFQGAPLSSY 504

Query: 507 VYVNPEDGRIFAQRTFDYELLQMLQIVVGVRDSGSPPLHANTSLHVFVLDENDNAPAVLH 566
           V +N + G ++A R+FDYE L+ LQ+ V   DSG+PPL +N SL +FVLD+NDN P +L+
Sbjct: 505 VSINSDTGVLYALRSFDYEQLRDLQLWVTASDSGNPPLSSNVSLSLFVLDQNDNTPEILY 564

Query: 567 PRPDWEHSAPQRL-PRSAPPGSLVTKVTAVDADAGHNAWLSYSLLPQSTAPGLFLVSTHT 625
           P    + S    L PRSA PG LVTKV AVD D+G NAWLSY LL +++ PGLF V  HT
Sbjct: 565 PALPTDGSTGVELAPRSAEPGYLVTKVVAVDKDSGQNAWLSYRLL-KASEPGLFAVGLHT 623

Query: 626 GEVRTARALLEDDSDTQQVVVLVRDNGDPSLSSTATVLLVLEDEDPEEMPKSSDFLIH-P 684
           GEVRTARALL+ D+  Q +VV V D+G P LS+T TV + + D  P+ +           
Sbjct: 624 GEVRTARALLDRDALKQSLVVAVEDHGQPPLSATFTVTVAVADRIPDILADLGSIKTPID 683

Query: 685 PERSDLTLYLIVALATVSLLSLVTFTFLSAKCLQGNADGDGGGGQCCRRQDSPSPDFYKQ 744
           PE  DLTLYL+VA+A VS + L     L    L+          +  R    P+  F   
Sbjct: 684 PEDLDLTLYLVVAVAAVSCVFLAFVIVLLVLRLRRWHKSRLLQAEGSRLAGVPASHF--- 740

Query: 745 SSPNLQVSSDGTLKYM-----EVTLRPTDSQSHCYRTCFSPASDGSDFTFLRPLSVQQPT 799
                 V  DG   ++     EV+L     +SH       P  + +D T L   S ++  
Sbjct: 741 ------VGVDGVRAFLQTYSHEVSLTADSRKSHL----IFPQPNYAD-TLLSEESCEKSE 789

Query: 800 ALALEPDAIRSRSNTLRERSQQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQFDTEM 859
            L +     +  +N    R QQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQFDTEM
Sbjct: 790 PLLMSD---KVDANKEERRVQQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQFDTEM 846

Query: 860 LQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATLTNA 919
           LQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATLTNA
Sbjct: 847 LQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATLTNA 906

Query: 920 AGKRDGKAPAGGNGNKKKSGKKEKK 944
           AGKRDGKAPAGGNGNKKKSGKKEKK
Sbjct: 907 AGKRDGKAPAGGNGNKKKSGKKEKK 931


>gi|11056026 protocadherin gamma subfamily A, 4 isoform 1 precursor
           [Homo sapiens]
          Length = 931

 Score =  854 bits (2206), Expect = 0.0
 Identities = 477/928 (51%), Positives = 609/928 (65%), Gaps = 39/928 (4%)

Query: 30  QLRYSVVEESEPGTLVGNVAQDLGLKMTDLLSRRLQLGSEENGRYFSLSLMSGALAVNQK 89
           Q+ YSV EE E G++VGN+A+DLGL   +L  R +++ S    + F+L+  SG L    +
Sbjct: 30  QILYSVFEEQEEGSVVGNIAKDLGLAPRELAERGVRIVSRGRTQLFALNPRSGTLVTAGR 89

Query: 90  IDRESLCGASTSCLLPVQVVTEHPLELIRVEVEILDLNDNSPSFATPEREMRISESAASG 149
           IDRE LC  S +C+  ++++ E  ++++RVEVEI+D+NDN PSF T +RE++++E+   G
Sbjct: 90  IDREELCDRSPNCVTNLEILLEDTVKILRVEVEIIDVNDNPPSFGTEQREIKVAENENPG 149

Query: 150 ARFPLDSAQDPDVGTNTVSFYTLSPNSHFSLNVKTLKDGKPFPELVLEQQLDREAQARHQ 209
           ARFPL  A DPDVG N++  Y L+ N +FSL+V++  DG  +PELVLE+ LDRE +A H 
Sbjct: 150 ARFPLPEAFDPDVGVNSLQGYQLNSNGYFSLDVQSGADGIKYPELVLERALDREEEAVHH 209

Query: 210 LVLTAVDGGTPARSGTTLISVIVLDINDNAPTFQSSVLRVGIPENAPIGTLLLRLNATDP 269
           LVLTA DGG P RSGT  I +I++D NDNAP F      V + EN P+GT LL + ATDP
Sbjct: 210 LVLTAFDGGDPVRSGTARILIILVDTNDNAPVFTQPEYHVSVRENVPVGTRLLTVKATDP 269

Query: 270 DEGTNGQLDYSFGDHTSEAVRNLFGLDPSSGAIHVLGPIDFEESRFYEIHARARDQGQPA 329
           DEG NG + YSF     + +  LF L+  SG I +LG +D+E+S FY+I   A D   P 
Sbjct: 270 DEGANGDVTYSFRK-VRDKISQLFQLNSLSGDITILGGLDYEDSGFYDIDVEAHDG--PG 326

Query: 330 MEGHCVIQVDVGDVNDNAPEVLLASLANPVLESTPVGTVVGLFNVRDRDSGRNGEVSLDI 389
           +     + V V D NDNAPEV + SL + V ES+  GTV+ LFNV D DSG NG V+  I
Sbjct: 327 LRARSKVLVTVLDENDNAPEVTVTSLTSSVQESSSPGTVIALFNVHDSDSGGNGLVTCSI 386

Query: 390 SPDLPFQI-KPSENHYSLLTSQPLDREATSHYIIELLASDAGSPSLHKHLTIRLNISDVN 448
             +LPF + K   N+Y LLT + LDRE  S Y I + A+D G+P L     I L + D+N
Sbjct: 387 PDNLPFTLEKTYGNYYRLLTHRTLDREEVSEYNITVTATDQGTPPLSTETHISLQVMDIN 446

Query: 449 DNAPRFNQQLYTAYILENRPPGSLLCTVAASDPDTGDNARLTYSIVGNQVQGAPASSFVY 508
           DN P F    Y+AYI EN P G+ + ++ A DPD+GDNAR+TYS+  +  QGAP SS+V 
Sbjct: 447 DNPPTFPHASYSAYIPENNPRGASILSMTAQDPDSGDNARITYSLAEDTFQGAPLSSYVS 506

Query: 509 VNPEDGRIFAQRTFDYELLQMLQIVVGVRDSGSPPLHANTSLHVFVLDENDNAPAVLHPR 568
           +N   G ++A  +FDYE  + LQ+++   DSG PPL +N SL +FVLD+NDN P +L+P 
Sbjct: 507 INSNTGILYALCSFDYEQFRDLQLLMTASDSGDPPLSSNVSLSLFVLDQNDNVPEILYPT 566

Query: 569 PDWEHSAPQRL-PRSAPPGSLVTKVTAVDADAGHNAWLSYSLLPQSTAPGLFLVSTHTGE 627
              + S    L PRSA  G LVTKV AVD D+G NAWLSYSLL +S+ PGLF V  HTGE
Sbjct: 567 FPTDGSTGVELAPRSADSGYLVTKVVAVDRDSGQNAWLSYSLL-KSSEPGLFAVGLHTGE 625

Query: 628 VRTARALLEDDSDTQQVVVLVRDNGDPSLSSTATVLLVLEDEDPE------EMPKSSDFL 681
           VRTARALL+ D+  Q++VV+V+D+G P LS+T T+ + + D  P+       +  S+D  
Sbjct: 626 VRTARALLDRDALKQRLVVVVQDHGQPPLSATVTLTVAVADSIPDVLADLGSLKPSAD-- 683

Query: 682 IHPPERSDLTLYLIVALATVSLLSLVTFTFLSAKCLQGNADGDGGGGQCCRRQDSPSPDF 741
              P+ S LTLYL+VA+A VS + L   T L A  L+          +  R    P+  F
Sbjct: 684 ---PDDSGLTLYLVVAVAAVSCVFLAFVTVLLALKLRRWHKSRLLHAEGSRLAGVPASHF 740

Query: 742 YKQSSPNLQVSSDGTLKYM-----EVTLRPTDSQSHCYRTCFSPASDGSDFTFLRPLSVQ 796
                    V  DG   ++     EV+L     +SH     FS  S     T +   S +
Sbjct: 741 ---------VGVDGVRAFLQTYSHEVSLTADSRKSHLI---FSQPSYAD--TLISRESCE 786

Query: 797 QPTALALEPDAIRSRSNTLRERSQQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQFD 856
           +   L +  D + ++ +      QQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQFD
Sbjct: 787 KSEPLLITQDLLETKGDP---NLQQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQFD 843

Query: 857 TEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATL 916
           TEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATL
Sbjct: 844 TEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATL 903

Query: 917 TNAAGKRDGKAPAGGNGNKKKSGKKEKK 944
           TNAAGKRDGKAPAGGNGNKKKSGKKEKK
Sbjct: 904 TNAAGKRDGKAPAGGNGNKKKSGKKEKK 931


>gi|14589880 protocadherin gamma subfamily A, 3 isoform 1 precursor
           [Homo sapiens]
          Length = 932

 Score =  851 bits (2198), Expect = 0.0
 Identities = 479/947 (50%), Positives = 616/947 (65%), Gaps = 46/947 (4%)

Query: 15  VLCML--SLCCWGWVSGQLRYSVVEESEPGTLVGNVAQDLGLKMTDLLSRRLQLGSEENG 72
           +LC L  +LC  G  SGQ+RYSV EE + G+ VGN+A DLGL+  +L  R +++ S    
Sbjct: 15  LLCALLGTLCETG--SGQIRYSVSEELDKGSFVGNIANDLGLEPRELAERGVRIVSRGRT 72

Query: 73  RYFSLSLMSGALAVNQKIDRESLCGASTSCLLPVQVVTEHPLELIRVEVEILDLNDNSPS 132
           + FSL+  SG+L   ++IDRE LC     CL+ + ++ E  L++  VE+EI D+NDN+P+
Sbjct: 73  QLFSLNPQSGSLVTAERIDREELCAQIPLCLVKINILVEDKLKIFEVEIEIKDINDNAPN 132

Query: 133 FATPEREMRISESAASGARFPLDSAQDPDVGTNTVSFYTLSPNSHFSLNVKTLKDGKPFP 192
           F T E E++I E    G RFP+ +A DPDVG N++  Y LSPN +FSL V ++ +G  +P
Sbjct: 133 FPTEELEIKIGELTVPGTRFPIKTAFDPDVGINSLQNYKLSPNDYFSLAVNSVSEGAKYP 192

Query: 193 ELVLEQQLDREAQARHQLVLTAVDGGTPARSGTTLISVIVLDINDNAPTFQSSVLRVGIP 252
           ELVLE+ LDRE +  HQLVL A DGG P  SG   I VIVLD NDN P F     RV + 
Sbjct: 193 ELVLERALDREKKEIHQLVLVASDGGDPVHSGNLHIQVIVLDANDNPPMFTQPEYRVSVW 252

Query: 253 ENAPIGTLLLRLNATDPDEGTNGQLDYSFGDHTSEAVRNLFGLDPSSGAIHVLGPIDFEE 312
           EN P+GT LL +NATDPDEG N Q+ Y   D     +  +F L+  SG + +L  +D+E+
Sbjct: 253 ENVPVGTRLLTVNATDPDEGFNAQVSYIL-DKMPGKIAEIFHLNSVSGEVSILKSLDYED 311

Query: 313 SRFYEIHARARDQGQPAMEGHCVIQVDVGDVNDNAPEVLLASLANPVLESTPVGTVVGLF 372
           + FYEI   A+D   P +     I V V DVNDNAPE+ + SL + V E   VG  + L 
Sbjct: 312 AMFYEIKIEAQDG--PGLLSRAKILVTVLDVNDNAPEITITSLTSSVPEEGTVGREIALI 369

Query: 373 NVRDRDSGRNGEVSLDISPDLPFQIKPS-ENHYSLLTSQPLDREATSHYIIELLASDAGS 431
           +V DRDSG+NG+V + +  +LPF+++ S + +Y L+T+  LDRE  S Y I L ASD GS
Sbjct: 370 DVHDRDSGQNGQVEVFVLGNLPFKLEKSIDQYYRLVTATSLDREQISEYNISLRASDGGS 429

Query: 432 PSLHKHLTIRLNISDVNDNAPRFNQQLYTAYILENRPPGSLLCTVAASDPDTGDNARLTY 491
           P L     I L++ D+NDN P F    Y+AYI EN P G+ + +V A DPD+ +NAR+TY
Sbjct: 430 PPLSTETHITLHVIDINDNPPTFPHLSYSAYIPENNPRGASIFSVTAQDPDSNNNARITY 489

Query: 492 SIVGNQVQGAPASSFVYVNPEDGRIFAQRTFDYELLQMLQIVVGVRDSGSPPLHANTSLH 551
           ++  + +QGAP SSFV +N   G ++A R+FDYE  + L+++V   DSG+PPL +N SL+
Sbjct: 490 ALTEDTLQGAPLSSFVSINSNTGVLYALRSFDYEQFRDLKLLVTASDSGNPPLSSNVSLN 549

Query: 552 VFVLDENDNAPAVLHPRPDWEHSAPQRL-PRSAPPGSLVTKVTAVDADAGHNAWLSYSLL 610
           +FVLD+NDNAP +L+P    + S    L PRSA PG LVTKV AVD D+G NAWLSY LL
Sbjct: 550 LFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSYRLL 609

Query: 611 PQSTAPGLFLVSTHTGEVRTARALLEDDSDTQQVVVLVRDNGDPSLSSTATVLLVLEDED 670
            +++ PGLF V  HTGEVRTARALL+ D+  Q +VV V+D+G P LS+T T+ + + D  
Sbjct: 610 -KASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADRI 668

Query: 671 PEEMPKSSDFLIHP---PERSDLTLYLIVALATVSLLSLVTFTFLSAKCLQG-----NAD 722
           P+ +       + P   P  SDLTLYL+VA+A VS + L     L A  L+         
Sbjct: 669 PDILADLGS--LEPSAKPNDSDLTLYLVVAVAAVSCVFLAFVIVLLALRLRRWHKSRLLQ 726

Query: 723 GDGGGGQCCRRQDSPSPDFYKQSSPNLQVSSDGTLKYM-----EVTLRPTDSQSHCYRTC 777
             GGG        +P   F         V +DG   ++     EV+L     +SH     
Sbjct: 727 ASGGG-----LASTPGSHF---------VGADGVRAFLQTYSHEVSLTADSRKSHL---- 768

Query: 778 FSPASDGSDFTFLRPLSVQQPTALALEPDAIRSRSNTLRERSQQAPPNTDWRFSQAQRPG 837
             P  + +D T +   S ++   L +  D +  + ++     QQAPPNTDWRFSQAQRPG
Sbjct: 769 IFPQPNYAD-TLISQESCEKSEPLLITQDLLEMKGDS--NLLQQAPPNTDWRFSQAQRPG 825

Query: 838 TSGSQNGDDTGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTL 897
           TSGSQNGDDTGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTL
Sbjct: 826 TSGSQNGDDTGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTL 885

Query: 898 QHVPDYRQNVYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK 944
           QHVPDYRQNVYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK
Sbjct: 886 QHVPDYRQNVYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK 932


>gi|11128037 protocadherin gamma subfamily B, 1 isoform 1 precursor
           [Homo sapiens]
          Length = 927

 Score =  846 bits (2185), Expect = 0.0
 Identities = 467/942 (49%), Positives = 614/942 (65%), Gaps = 48/942 (5%)

Query: 18  MLSLCCWGWVSGQLRYSVVEESEPGTLVGNVAQDLGLKMTDLLSRRLQLGSEENGRYFSL 77
           +LSL C G +S Q+RY++ EE   G+ VG +A+DLGL + +L +R+L++ +E+   YF++
Sbjct: 19  LLSLFC-GAISQQIRYTIPEELANGSRVGKLAKDLGLSVRELPTRKLRVSAED---YFNV 74

Query: 78  SLMSGALAVNQKIDRESLCGASTSCLLPVQVVTEHPLELIRVEVEILDLNDNSPSFATPE 137
           SL SG L VN +IDRE +CG    C L  + V E+P+ +  V V I D+NDN+P F    
Sbjct: 75  SLESGDLLVNGRIDREKICGRKLECALEFETVAENPMNVFHVVVVIQDINDNAPRFVAKG 134

Query: 138 REMRISESAASGARFPLDSAQDPDVGTNTVSFYTLSPNSHFSLNVKTLKDGKPFPELVLE 197
            ++ I ESA  G +F LDSAQD DV  N++  YT++PN +FSL+ K   DG  +P L+LE
Sbjct: 135 IDLEICESALPGVKFSLDSAQDADVEGNSLKLYTINPNQYFSLSTKESPDGSKYPVLLLE 194

Query: 198 QQLDREAQARHQLVLTAVDGGTPARSGTTLISVIVLDINDNAPTFQSSVLRVGIPENAPI 257
           + LDRE Q+ H+L+LTA+DGG P  SGTT I + V D NDNAP F   V RV + EN P 
Sbjct: 195 KPLDREHQSSHRLILTAMDGGDPPLSGTTHIWIRVTDANDNAPVFSQEVYRVSLQENVPW 254

Query: 258 GTLLLRLNATDPDEGTNGQLDYSFGDHTSEAVRNLFGLDPSSGAIHVLGPIDFEESRFYE 317
           GT +LR+ ATD DEG N ++ Y+F +  S    +LF L+P++G I   G +DFEE+  Y 
Sbjct: 255 GTSVLRVMATDQDEGINAEITYAFLN--SPISTSLFNLNPNTGDITTNGTLDFEETSRYV 312

Query: 318 IHARARDQGQPAMEGHCVIQVDVGDVNDNAPEVLLASLANPVLESTPVGTVVGLFNVRDR 377
           +   A+D G      HC +Q+++ D NDNAPEV   S +N + E + +GTV+ L  VRD+
Sbjct: 313 LSVEAKDGG--VHTAHCNVQIEIVDENDNAPEVTFMSFSNQIPEDSDLGTVIALIKVRDK 370

Query: 378 DSGRNGEVSLDISPDLPFQIKP-SENHYSLLTSQPLDREATSHYIIELLASDAGSPSLHK 436
           DSG+NG V+     ++PF+++  S+N+Y L+ +  L+RE T+ Y + ++A+D G P+L  
Sbjct: 371 DSGQNGMVTCYTQEEVPFKLESTSKNYYKLVIAGALNREQTADYNVTIIATDKGKPALSS 430

Query: 437 HLTIRLNISDVNDNAPRFNQQLYTAYILENRPPGSLLCTVAASDPDTGDNARLTYSIVGN 496
             +I L+ISD+NDNAP F+Q  Y  ++ EN PPG+ +  V+ASDPD G N R++YSI+ +
Sbjct: 431 RTSITLHISDINDNAPVFHQASYVVHVSENNPPGASIAQVSASDPDLGPNGRVSYSILAS 490

Query: 497 QVQGAPASSFVYVNPEDGRIFAQRTFDYELLQMLQIVVGVRDSGSPPLHANTSLHVFVLD 556
            ++     S+V V+P+ G +FAQR FD+E L+  ++ +  RD GSP L AN SL V V D
Sbjct: 491 DLEPRELLSYVSVSPQSGVVFAQRAFDHEQLRAFELTLQARDQGSPALSANVSLRVLVGD 550

Query: 557 ENDNAPAVLHPRPDWEHSAP-QRLPRSAPPGSLVTKVTAVDADAGHNAWLSYSLLPQSTA 615
            NDNAP VL+P    + SA    +PR+A PG LVTKV AVDAD+GHNAWLSY +L Q++ 
Sbjct: 551 LNDNAPRVLYPALGPDGSALFDMVPRAAEPGYLVTKVVAVDADSGHNAWLSYHVL-QASE 609

Query: 616 PGLFLVSTHTGEVRTARALLEDDSDTQQVVVLVRDNGDPSLSSTATVLLVLEDEDPEEMP 675
           PGLF +   TGEVRTARAL + D+  Q+++V VRD G P LS+TAT+ L+  D   E +P
Sbjct: 610 PGLFSLGLRTGEVRTARALGDRDAARQRLLVAVRDGGQPPLSATATLHLIFADSLQEVLP 669

Query: 676 KSSDFLIHPPERSDLTLYLIVALATVSLLSLVTFTFLSAKCLQGNADGDGGG----GQCC 731
             SD       +++L  YL+VALA +S+L L+      A  L+ ++  D  G    G C 
Sbjct: 670 DLSDRPEPSDPQTELQFYLVVALALISVLFLLAVILAIALRLRRSSSLDTEGCFQTGLCS 729

Query: 732 RRQDSPSPDFYKQSSPNLQVSSDGTLKYMEVTLRPTDSQSHCYRTCFSPASDGSDFTFLR 791
           +      P+            S+GTL Y              Y  C +  S  ++F  L 
Sbjct: 730 KSGPGVPPNH-----------SEGTLPYS-------------YNLCIASHSAKTEFNSLN 765

Query: 792 --PLSVQQPTALALEPDAIRSRSNTLRE-------RSQQAPPNTDWRFSQAQRPGTSGSQ 842
             P        L  +P  +   SN   +        S QAPPNTDWRFSQAQRPGTSGSQ
Sbjct: 766 LTPEMAPPQDLLCDDPSMVVCASNEDHKIAYDPSLSSHQAPPNTDWRFSQAQRPGTSGSQ 825

Query: 843 NGDDTGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPD 902
           NGDDTGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPD
Sbjct: 826 NGDDTGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPD 885

Query: 903 YRQNVYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK 944
           YRQNVYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK
Sbjct: 886 YRQNVYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK 927


>gi|11056030 protocadherin gamma subfamily A, 2 isoform 1 precursor
           [Homo sapiens]
          Length = 932

 Score =  840 bits (2170), Expect = 0.0
 Identities = 476/947 (50%), Positives = 607/947 (64%), Gaps = 40/947 (4%)

Query: 12  KWQVLCMLSLCCWGWVSGQLRYSVVEESEPGTLVGNVAQDLGLKMTDLLSRRLQLGSEEN 71
           K  +LC L    W   +GQ+RYSV EE + G+ VGN+A+DLGL+   L  + +++ S   
Sbjct: 12  KLVLLCFLLATLWEARAGQIRYSVREEIDRGSFVGNIAKDLGLEPLALAEQGVRIVSRGR 71

Query: 72  GRYFSLSLMSGALAVNQKIDRESLCGASTSCLLPVQVVTEHPLELIRVEVEILDLNDNSP 131
            + F+L+  SG+L    +IDRE LC  S  CLL   ++ E  L +  VEVEI D+NDN+P
Sbjct: 72  SQLFALNPRSGSLVTANRIDREELCAQSAPCLLNFNILLEDKLTIYSVEVEITDINDNAP 131

Query: 132 SFATPEREMRISESAASGARFPLDSAQDPDVGTNTVSFYTLSPNSHFSLNVKTLKDGKPF 191
            F   E E++ISE+   G R PL +A D DVG N +  Y L+PN HFSL+V+   DG  +
Sbjct: 132 RFGVEELELKISETTTPGFRIPLKNAHDADVGENALQKYALNPNDHFSLDVRRGADGNKY 191

Query: 192 PELVLEQQLDREAQARHQLVLTAVDGGTPARSGTTLISVIVLDINDNAPTFQSSVLRVGI 251
           PELVLE+ LDRE +A H LVL A DGG P  SGT+ I V VLD NDNAP F     R+ I
Sbjct: 192 PELVLERSLDREEEAVHHLVLVASDGGDPVLSGTSRICVKVLDANDNAPVFTQPEYRISI 251

Query: 252 PENAPIGTLLLRLNATDPDEGTNGQLDYSFGDHTSEAVRNLFGLDPSSGAIHVLGPIDFE 311
           PEN  +GT +L + ATD DEG   Q+ Y F + +      +F L  +SG + ++  +D+E
Sbjct: 252 PENTLVGTRILTVTATDADEGYYAQVVY-FLEKSPGETSEVFELKSTSGELTIIKDLDYE 310

Query: 312 ESRFYEIHARARDQGQPAMEGHCVIQVDVGDVNDNAPEVLLASLANPVLESTPVGTVVGL 371
           ++ F+EI   A+D   P +     + V V DVNDNAPE  + S  + V E +  GT++GL
Sbjct: 311 DATFHEIDIEAQDG--PGLLTRAKVIVTVLDVNDNAPEFYMTSATSSVSEDSLPGTIIGL 368

Query: 372 FNVRDRDSGRNGEVSLDISPDLPFQIKPS-ENHYSLLTSQPLDREATSHYIIELLASDAG 430
           FNV DRDSG+N   +  +  DLPF+++ S +N+Y L+T++ LDRE  S Y I L A D G
Sbjct: 369 FNVHDRDSGQNAFTTCSLPEDLPFKLEKSVDNYYRLVTTRALDREQFSFYNITLTAKDGG 428

Query: 431 SPSLHKHLTIRLNISDVNDNAPRFNQQLYTAYILENRPPGSLLCTVAASDPDTGDNARLT 490
           +PSL     I L ++D+NDNAP F++  Y+ YI EN P G+ + +V A DPD+ DNA +T
Sbjct: 429 NPSLSTDAHILLQVADINDNAPAFSRTSYSTYIPENNPRGASVFSVTAHDPDSNDNAHVT 488

Query: 491 YSIVGNQVQGAPASSFVYVNPEDGRIFAQRTFDYELLQMLQIVVGVRDSGSPPLHANTSL 550
           YS   + VQGAP SS++ +N + G ++A R+FDYE L+ LQ+ V  RDSG+PPL +N SL
Sbjct: 489 YSFAEDTVQGAPLSSYISINSDTGVLYALRSFDYEQLRDLQVWVIARDSGNPPLSSNVSL 548

Query: 551 HVFVLDENDNAPAVLHPRPDWEHSAPQRL-PRSAPPGSLVTKVTAVDADAGHNAWLSYSL 609
            +FVLD+NDNAP +L+P    + S    L PRSA PG LVTKV AVD D+G NAWLSY L
Sbjct: 549 SLFVLDQNDNAPEILYPAFPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSYHL 608

Query: 610 LPQSTAPGLFLVSTHTGEVRTARALLEDDSDTQQVVVLVRDNGDPSLSSTATVLLVLEDE 669
           L +++ PGLF V  HTGEVRTARALL+ D+  Q +VV ++D+G P LS+T T+ + + D 
Sbjct: 609 L-KASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAIQDHGQPPLSATVTLTVAVADR 667

Query: 670 DPEEMPKSSDFLIHP---PERSDLTLYLIVALATVSLLSLVTFTFLSAKCLQGNADG--- 723
            P+ +       + P   P  SDLTLYL+VA+A VS + L     L A  L+        
Sbjct: 668 IPDILADLGS--LEPSAIPNDSDLTLYLVVAVAAVSCVFLAFVIVLLAHRLRRWHKSRLL 725

Query: 724 DGGGGQCCRRQDSPSPDFYKQSSPNLQVSSDGTLKYM-----EVTLRPTDSQSHCYRTCF 778
              GG     Q S              V  DG   ++     EV+L     +SH      
Sbjct: 726 QASGGSLTGMQSSHF------------VGVDGVRAFLQTYSHEVSLTADSRKSHL----I 769

Query: 779 SPASDGSDFTFLRPLSVQQPTALALEPDAIRS-RSNTLRERSQQAPPNTDWRFSQAQRPG 837
            P  + +D T +   S ++   L+     +   R  T    SQQAPPNTDWRFSQAQRPG
Sbjct: 770 FPQPNYAD-TLISQESCEKKDFLSAPQSLLEEEREETF---SQQAPPNTDWRFSQAQRPG 825

Query: 838 TSGSQNGDDTGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTL 897
           TSGSQNGDDTGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTL
Sbjct: 826 TSGSQNGDDTGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTL 885

Query: 898 QHVPDYRQNVYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK 944
           QHVPDYRQNVYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK
Sbjct: 886 QHVPDYRQNVYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK 932


>gi|8850232 protocadherin gamma subfamily A, 12 isoform 1 precursor
           [Homo sapiens]
          Length = 932

 Score =  839 bits (2168), Expect = 0.0
 Identities = 478/943 (50%), Positives = 612/943 (64%), Gaps = 58/943 (6%)

Query: 26  WVSG--QLRYSVVEESEPGTLVGNVAQDLGLKMTDLLSRRLQLGSEENGRYFSLSLMSGA 83
           W +G  Q+RYSV EE E G+ VG++++DLGL+  +L  R +++      + F+L+  SG+
Sbjct: 24  WETGCTQIRYSVPEELEKGSRVGDISRDLGLEPRELAERGVRIIPRGRTQLFALNPRSGS 83

Query: 84  LAVNQKIDRESLCGASTSCLLPVQVVTEHPLELIRVEVEILDLNDNSPSFATPEREMRIS 143
           L    +IDRE LC  +  C L + ++ E  +++  VEVE+ D+NDN+P F   E E++IS
Sbjct: 84  LVTAGRIDREELCMGAIKCQLNLDILMEDKVKIYGVEVEVRDINDNAPYFRESELEIKIS 143

Query: 144 ESAASGARFPLDSAQDPDVGTNTVSFYTLSPNSHFSLNVKTLKDGKPFPELVLEQQLDRE 203
           E+AA+  RFPL  A DPD+G N++  Y LSPN+HFSL V+   DG  +PELVL++ LDRE
Sbjct: 144 ENAATEMRFPLPHAWDPDIGKNSLQSYELSPNTHFSLIVQNGADGSKYPELVLKRALDRE 203

Query: 204 AQARHQLVLTAVDGGTPARSGTTLISVIVLDINDNAPTFQSSVLRVGIPENAPIGTLLLR 263
            +A H LVLTA DGG P R+GT  I V+VLD NDNAP F     R  +PEN  +GT LL 
Sbjct: 204 EKAAHHLVLTASDGGDPVRTGTARIRVMVLDANDNAPAFAQPEYRASVPENLALGTQLLV 263

Query: 264 LNATDPDEGTNGQLDYSFGDHTSEAVRNLFGLDPSSGAIHVLGPIDFEESRFYEIHARAR 323
           +NATDPDEG N ++ YSF  +  +    +F LD +SG I  +G +D EES FY++  +A 
Sbjct: 264 VNATDPDEGVNAEVRYSFR-YVDDKAAQVFKLDCNSGTISTIGELDHEESGFYQMEVQAM 322

Query: 324 DQGQPAMEGHCVIQVDVGDVNDNAPEVLLASLANPVLESTPVGTVVGLFNVRDRDSGRNG 383
           D           + + V DVNDNAPEV+L SLA+ V E++P GT++ L NV D+DS  NG
Sbjct: 323 DNA--GYSARAKVLITVLDVNDNAPEVVLTSLASSVPENSPRGTLIALLNVNDQDSEENG 380

Query: 384 EVSLDISPDLPFQIKPSE-NHYSLLTSQPLDREATSHYIIELLASDAGSPSLHKHLTIRL 442
           +V   I  +LPF+++ S  N+YSL+T   LDRE    Y I + A+D G+P L     I L
Sbjct: 381 QVICFIQGNLPFKLEKSYGNYYSLVTDIVLDREQVPSYNITVTATDRGTPPLSTETHISL 440

Query: 443 NISDVNDNAPRFNQQLYTAYILENRPPGSLLCTVAASDPDTGDNARLTYSIVGNQVQGAP 502
           N++D NDN P F Q  Y+AYI EN P G  L +V A DPD  +NA++TYS+  N +QGA 
Sbjct: 441 NVADTNDNPPVFPQASYSAYIPENNPRGVSLVSVTAHDPDCEENAQITYSLAENTIQGAS 500

Query: 503 ASSFVYVNPEDGRIFAQRTFDYELLQMLQIVVGVRDSGSPPLHANTSLHVFVLDENDNAP 562
            SS+V +N + G ++A  +FDYE  + LQ+ V  RD+G PPL +N SL +FVLD+NDNAP
Sbjct: 501 LSSYVSINSDTGVLYALSSFDYEQFRDLQVKVMARDNGHPPLSSNVSLSLFVLDQNDNAP 560

Query: 563 AVLHPRPDWEHSAPQRL-PRSAPPGSLVTKVTAVDADAGHNAWLSYSLLPQSTAPGLFLV 621
            +L+P    + S    L PRSA PG LVTKV AVD D+G NAWLSY LL +++ PGLF V
Sbjct: 561 EILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSYRLL-KASEPGLFSV 619

Query: 622 STHTGEVRTARALLEDDSDTQQVVVLVRDNGDPSLSSTATVLLVLEDEDPE--------E 673
             HTGEVRTARALL+ D+  Q +VV V+D+G P LS+T T+ + + D  P+        E
Sbjct: 620 GLHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADSIPQVLADLGSLE 679

Query: 674 MPKSSDFLIHPPERSDLTLYLIVALATVSLLSLVTFTFLSAKCLQG-------NADGDGG 726
            P +S       E SDLTLYL+VA+A VS + L     L A  L+         A G G 
Sbjct: 680 SPANS-------ETSDLTLYLVVAVAAVSCVFLAFVILLLALRLRRWHKSRLLQASGGGL 732

Query: 727 GGQCCRRQDSPSPDFYKQSSPNLQVSSDGTLKYM-----EVTLRPTDSQSHCYRTCFSPA 781
            G       +P+  F         V  DG   ++     EV+L     +SH       P 
Sbjct: 733 TG-------APASHF---------VGVDGVQAFLQTYSHEVSLTTDSRKSHL----IFPQ 772

Query: 782 SDGSDFTFLRPLSVQQPTALALEPDAIRSRSNTLRERSQQAPPNTDWRFSQAQRPGTSGS 841
            + +D    +  S ++   L L  D++ S+ +      +QAPPNTDWRFSQAQRPGTSGS
Sbjct: 773 PNYADMLVSQE-SFEKSEPLLLSGDSVFSKDS--HGLIEQAPPNTDWRFSQAQRPGTSGS 829

Query: 842 QNGDDTGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVP 901
           QNGDDTGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVP
Sbjct: 830 QNGDDTGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVP 889

Query: 902 DYRQNVYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK 944
           DYRQNVYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK
Sbjct: 890 DYRQNVYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK 932


>gi|11056065 protocadherin gamma subfamily A, 6 isoform 1 precursor
           [Homo sapiens]
          Length = 932

 Score =  839 bits (2168), Expect = 0.0
 Identities = 474/957 (49%), Positives = 613/957 (64%), Gaps = 43/957 (4%)

Query: 3   PKTLPQLAGKWQVLCMLSLCCWGWVSGQLRYSVVEESEPGTLVGNVAQDLGLKMTDLLSR 62
           P+  PQ + +  +L +L    WG  + Q+RYS+ EE E G+ VGN+ +DLGL+  +L   
Sbjct: 4   PQRHPQRSEQVLLLTLLGTL-WGAAAAQIRYSIPEELEKGSFVGNIVKDLGLEPQELAEH 62

Query: 63  RLQLGSEENGRYFSLSLMSGALAVNQKIDRESLCGASTSCLLPVQVVTEHPLELIRVEVE 122
            +++ S    + FSL+  +G+L    +IDRE LC  S  CL+   ++ E  L L  VEVE
Sbjct: 63  GVRIVSRGRMQLFSLNPRNGSLVTAGRIDREELCAQSPRCLVSFNILVEDKLNLYPVEVE 122

Query: 123 ILDLNDNSPSFATPEREMRISESAASGARFPLDSAQDPDVGTNTVSFYTLSPNSHFSLNV 182
           I+D+NDN+P F   E E++I E+AA  +RFPL    DPDVG N++  + LS NSHFS++V
Sbjct: 123 IVDINDNTPRFLKEELEVKILENAAPSSRFPLMEVYDPDVGMNSLQGFKLSGNSHFSVDV 182

Query: 183 KTLKDGKPFPELVLEQQLDREAQARHQLVLTAVDGGTPARSGTTLISVIVLDINDNAPTF 242
           ++   G  +PELVLE  LDRE +A ++LVLTA+DGG P RS    I V VLD+NDN P F
Sbjct: 183 QSEAHGPKYPELVLEGTLDREGEAVYRLVLTAMDGGDPVRSSVAQILVTVLDVNDNTPMF 242

Query: 243 QSSVLRVGIPENAPIGTLLLRLNATDPDEGTNGQLDYSFGDHTSEAVRNLFGLDPSSGAI 302
              V RV +PEN P+GT +L + ATD DEG +G++ YSF   T E +  +F L+  +G I
Sbjct: 243 TQPVYRVSVPENLPVGTPVLAVTATDQDEGVHGEVTYSFVKIT-EKISQIFCLNVLTGEI 301

Query: 303 HVLGPIDFEESRFYEIHARARDQGQPAMEGHCVIQVDVGDVNDNAPEVLLASLANPVLES 362
                +D+E+S FYE+   ARD   P +     + + + DVNDN PEV++ S +  + ES
Sbjct: 302 STSANLDYEDSSFYELGVEARDG--PGLRDRAKVLITILDVNDNVPEVVVTSGSRTIAES 359

Query: 363 TPVGTVVGLFNVRDRDSGRNGEVSLDISPDLPFQIKPSE-NHYSLLTSQPLDREATSHYI 421
            P GTV+ LF V DRDSG NG V+  I   LPF+++ S  N+Y L+T+  LDRE    Y 
Sbjct: 360 APPGTVIALFQVFDRDSGLNGLVTCSIPRSLPFELEKSVGNYYRLVTNAALDREEVFLYN 419

Query: 422 IELLASDAGSPSLHKHLTIRLNISDVNDNAPRFNQQLYTAYILENRPPGSLLCTVAASDP 481
           I + A+D G+P L     I LN++D NDN P F    Y+ Y+LEN P G+ + +V A DP
Sbjct: 420 ITVTATDKGTPPLSTETIISLNVADTNDNPPTFPHSSYSVYVLENNPRGASIFSVNALDP 479

Query: 482 DTGDNARLTYSIVGNQVQGAPASSFVYVNPEDGRIFAQRTFDYELLQMLQIVVGVRDSGS 541
           D   NA+++YS+  + +QGAP SS+V +N + G ++A R+FDYE L+ LQ+ V   DSG 
Sbjct: 480 DVDQNAQVSYSLAEDTLQGAPLSSYVSINSDTGILYALRSFDYEQLRDLQLWVTASDSGD 539

Query: 542 PPLHANTSLHVFVLDENDNAPAVLHPRPDWEHSAPQRL-PRSAPPGSLVTKVTAVDADAG 600
           PPL +N SL +FVLD+NDNAP +L+P    + S    L PRSA PG LVTKV AVD D+G
Sbjct: 540 PPLSSNVSLSLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSG 599

Query: 601 HNAWLSYSLLPQSTAPGLFLVSTHTGEVRTARALLEDDSDTQQVVVLVRDNGDPSLSSTA 660
            NAWLSY LL +++ PGLF V  HTGEVRTARALL+ D+  Q +VV V+D+G P LS+T 
Sbjct: 600 QNAWLSYRLL-KASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATV 658

Query: 661 TVLLVLEDEDPEEMPKSSDFLIHP---PERSDLTLYLIVALATVSLLSLVTFTFLSAKCL 717
           T+ + + D  P+ +       + P   P  SDLTLYL+VA+A VS + L     L A  L
Sbjct: 659 TLTVAVADRIPDILADLGS--LEPSAKPNDSDLTLYLVVAVAAVSCVFLAFVIVLLALRL 716

Query: 718 QG-----NADGDGGGGQCCRRQDSPSPDFYKQSSPNLQVSSDGTLKYM-----EVTLRPT 767
           Q           GGG         P   F         V  +G   ++     EV+L   
Sbjct: 717 QRWHKSRLLQASGGG-----LASMPGSHF---------VGVEGVRAFLQTYSHEVSLTAD 762

Query: 768 DSQSHCYRTCFSPASDGSDFTFLRPLSVQQPTALALEPDAIRSRSNTLRERSQQAPPNTD 827
             +SH       P  + +D T +   S ++   L +  D + ++      + QQAPPNTD
Sbjct: 763 SRKSHL----IFPQPNYAD-TLINQESYEKSEPLLITQDLLETKGEP--RQLQQAPPNTD 815

Query: 828 WRFSQAQRPGTSGSQNGDDTGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGL 887
           WRFSQAQRPGTSGSQNGDDTGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGL
Sbjct: 816 WRFSQAQRPGTSGSQNGDDTGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGL 875

Query: 888 SARYGPQFTLQHVPDYRQNVYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK 944
           SARYGPQFTLQHVPDYRQNVYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK
Sbjct: 876 SARYGPQFTLQHVPDYRQNVYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK 932


>gi|11128043 protocadherin gamma subfamily A, 9 isoform 1 precursor
           [Homo sapiens]
          Length = 932

 Score =  838 bits (2166), Expect = 0.0
 Identities = 478/961 (49%), Positives = 614/961 (63%), Gaps = 46/961 (4%)

Query: 1   MGPKTLPQLAGKWQVLCMLSLCCWGWVSGQLRYSVVEESEPGTLVGNVAQDLGLKMTDLL 60
           M   T  QL G+  +LC L    W   + Q+RYSV EE+E G +VGN+++DL L+  +L 
Sbjct: 1   MAAPTKCQLRGRLVLLCSLLGMLWEARASQIRYSVPEETEKGYIVGNISKDLALEPRELA 60

Query: 61  SRRLQLGSEENGRYFSLSLMSGALAVNQKIDRESLCGASTSCLLPVQVVTEHPLELIRVE 120
            RR+++ S    + FSL+  SG L    +IDRE LC  S  CL+  +V+ E  ++L  +E
Sbjct: 61  ERRVRIVSRGRTQLFSLNPRSGTLVTAGRIDREELCAQSPRCLVNFKVLVEDRVKLYGIE 120

Query: 121 VEILDLNDNSPSFATPEREMRISESAASGARFPLDSAQDPDVGTNTVSFYTLSPNSHFSL 180
           +E+ D+ND++P F     E++I+E A  GAR+PL  A DPDVG N++  Y LSPN HFSL
Sbjct: 121 IEVTDINDSAPKFQAESLEVKINEIAVPGARYPLPEAIDPDVGVNSLQSYQLSPNHHFSL 180

Query: 181 NVKTLKDGKPFPELVLEQQLDREAQARHQLVLTAVDGGTPARSGTTLISVIVLDINDNAP 240
           NV+T  +G   PELVLE+ LDRE    H LVLTA DGG P RS T  I V VLD NDNAP
Sbjct: 181 NVQTGDNGAINPELVLERALDREEATAHHLVLTASDGGEPRRSSTVRIHVTVLDTNDNAP 240

Query: 241 TFQSSVLRVGIPENAPIGTLLLRLNATDPDEGTNGQLDYSFGDHTSEAVRNLFGLDPSSG 300
            F   + RV + EN P GT LL   A+D DEG NG++ Y F    +E    LF L+ ++G
Sbjct: 241 VFAQRIYRVKVLENVPPGTWLLTATASDLDEGINGKVAYKFWK-INEKQSLLFQLNENTG 299

Query: 301 AIHVLGPIDFEESRFYEIHARARDQGQPAMEGHCVIQVDVGDVNDNAPEVLLASLANPVL 360
            I     +D+EE  FYE+  +A D G   ++G   + + V DVNDN PEV + SL +PV 
Sbjct: 300 EISTAKSLDYEECSFYEMEIQAEDGG--GLKGWTKVLISVEDVNDNRPEVTITSLFSPVR 357

Query: 361 ESTPVGTVVGLFNVRDRDSGRNGEVSLDISPDLPFQIKPSE-NHYSLLTSQPLDREATSH 419
           E  P GTV+ LFN  DRDSG+NG+V   I  +L F ++ SE ++Y LLT+Q LDRE  S 
Sbjct: 358 EDAPQGTVILLFNAHDRDSGKNGQVVCSIQENLSFTLENSEEDYYRLLTAQILDREKASE 417

Query: 420 YIIELLASDAGSPSLHKHLTIRLNISDVNDNAPRFNQQLYTAYILENRPPGSLLCTVAAS 479
           Y I + A+D G+P L   + I L ++D+NDN P F+Q  Y+ Y+ EN   G+ + +V A 
Sbjct: 418 YNITVTATDRGTPPLSTEIHITLQVTDINDNPPAFSQASYSVYLPENNARGTSIFSVIAY 477

Query: 480 DPDTGDNARLTYSIVGNQVQGAPASSFVYVNPEDGRIFAQRTFDYELLQMLQIVVGVRDS 539
           DPD+ +N+R+ YS+  + +QG+P S++V +N + G ++A  +FDYE  + LQ+ V   DS
Sbjct: 478 DPDSNENSRVIYSLAEDTIQGSPLSTYVSINSDTGVLYALCSFDYEQFRDLQMQVTASDS 537

Query: 540 GSPPLHANTSLHVFVLDENDNAPAVLHPRPDWEHSAPQRL-PRSAPPGSLVTKVTAVDAD 598
           GSPPL +N SL +FVLD+NDNAP +L+P    + S    L PRSA PG LVTKV AVD D
Sbjct: 538 GSPPLSSNVSLRLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRD 597

Query: 599 AGHNAWLSYSLLPQSTAPGLFLVSTHTGEVRTARALLEDDSDTQQVVVLVRDNGDPSLSS 658
           +G NAWLSY L  +++ PGLF V  HTGEVRTARALL+ D+  Q +VV V+D+G P LS+
Sbjct: 598 SGQNAWLSYRLF-KASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSA 656

Query: 659 TATVLLVLEDEDPEEMPKSSDFLIHPP-ERSDLTLYLIVALATVS---------LLSLVT 708
           T T+ + + D  P+ +       I    E SDLTLYL+VA+A VS         LL+L  
Sbjct: 657 TVTLTVAIADSIPDILADLGSLQIPADLEASDLTLYLVVAVAVVSCVFLTFVITLLALRL 716

Query: 709 FTFLSAKCLQGNADGDGGGGQCCRRQDSPSPDFYKQSSPNLQVSSDGTLKYM-----EVT 763
             + S+  L+  +DG  G          P+  F         V  DG   ++     E +
Sbjct: 717 RHWHSSHLLRATSDGLAG---------VPTSHF---------VGVDGVRAFLQTYSQEFS 758

Query: 764 LRPTDSQSHCYRTCFSPASDGSDFTFLRPLSVQQPTALALEPDAIRSRSNTLRERSQQAP 823
           L     +SH       P  + +D T +   S ++   L +  D+     +T      QAP
Sbjct: 759 LTADSRKSHL----IFPQPNYAD-TLISQQSCEKNEPLCVSVDSKFPIEDT--PLVPQAP 811

Query: 824 PNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAG 883
           PNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAG
Sbjct: 812 PNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAG 871

Query: 884 TMGLSARYGPQFTLQHVPDYRQNVYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEK 943
           TMGLSARYGPQFTLQHVPDYRQNVYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEK
Sbjct: 872 TMGLSARYGPQFTLQHVPDYRQNVYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEK 931

Query: 944 K 944
           K
Sbjct: 932 K 932


>gi|14270484 protocadherin gamma subfamily A, 8 isoform 1 precursor
           [Homo sapiens]
          Length = 932

 Score =  833 bits (2153), Expect = 0.0
 Identities = 472/951 (49%), Positives = 618/951 (64%), Gaps = 31/951 (3%)

Query: 3   PKTLPQLAGKWQVLCMLSLCCWGWVSGQLRYSVVEESEPGTLVGNVAQDLGLKMTDLLSR 62
           P++ P+  G+  +LC L    W    GQ+RYSV EE++ G+ VGN+++DLGL    L   
Sbjct: 4   PQSRPR-RGELILLCALLGTLWEIGRGQIRYSVPEETDKGSFVGNISKDLGLDPRKLAKH 62

Query: 63  RLQLGSEENGRYFSLSLMSGALAVNQKIDRESLCGASTSCLLPVQVVTEHPLELIRVEVE 122
            +++ S    + F+L+  SG+L    +IDRE LC  S  CL+ +  + E   +L  VE+E
Sbjct: 63  GVRIVSRGRTQLFALNPRSGSLITAGRIDREELCAQSPRCLININTLVEDKGKLFGVEIE 122

Query: 123 ILDLNDNSPSFATPEREMRISESAASGARFPLDSAQDPDVGTNTVSFYTLSPNSHFSLNV 182
           I+D+NDN+P F   + E++I+E A  GAR+PL  A DPDVG N++  Y LSPN HFSL+V
Sbjct: 123 IIDINDNNPKFQVEDLEVKINEIAVPGARYPLPEAVDPDVGVNSLQSYQLSPNHHFSLDV 182

Query: 183 KTLKDGKPFPELVLEQQLDREAQARHQLVLTAVDGGTPARSGTTLISVIVLDINDNAPTF 242
           +T  +G   PELVLE+ LDRE +A H LVLTA DGG P RS T  I V VLD NDNAP F
Sbjct: 183 QTGDNGAINPELVLERALDREEEAAHHLVLTASDGGKPPRSSTVRIHVTVLDTNDNAPVF 242

Query: 243 QSSVLRVGIPENAPIGTLLLRLNATDPDEGTNGQLDYSFGDHTSEAVRNLFGLDPSSGAI 302
              + RV + EN P GT LL + A+DPDEG NG++ Y F    +E    LF L+ ++G I
Sbjct: 243 PHPIYRVKVLENMPPGTRLLTVTASDPDEGINGKVAYKF-RKINEKQTPLFQLNENTGEI 301

Query: 303 HVLGPIDFEESRFYEIHARARDQGQPAMEGHCVIQVDVGDVNDNAPEVLLASLANPVLES 362
            +   +D+EE  FYE+  +A D G  A+ G   + + V DVNDN PEV++ SL +PVLE+
Sbjct: 302 SIAKSLDYEECSFYEMEIQAEDVG--ALLGRTKLLISVEDVNDNRPEVIITSLFSPVLEN 359

Query: 363 TPVGTVVGLFNVRDRDSGRNGEVSLDISPDLPFQIKPS-ENHYSLLTSQPLDREATSHYI 421
           +  GTV+   +V D+DSG+NG+V      +LPF+++ S  N+Y L+T + LDRE  S Y 
Sbjct: 360 SLPGTVIAFLSVHDQDSGKNGQVVCYTRDNLPFKLEKSIGNYYRLVTRKYLDRENVSIYN 419

Query: 422 IELLASDAGSPSLHKHLTIRLNISDVNDNAPRFNQQLYTAYILENRPPGSLLCTVAASDP 481
           I ++ASD G+P L     I L+++D+NDN P F    Y+AYILEN   G+ + ++ A DP
Sbjct: 420 ITVMASDLGTPPLSTETQIALHVADINDNPPTFPHASYSAYILENNLRGASIFSLTAHDP 479

Query: 482 DTGDNARLTYSIVGNQVQGAPASSFVYVNPEDGRIFAQRTFDYELLQMLQIVVGVRDSGS 541
           D+ +NA++TYS+  + +QGAP SS++ +N + G ++A ++FDYE ++ LQ++V   DSG 
Sbjct: 480 DSQENAQVTYSVTEDTLQGAPLSSYISINSDTGVLYALQSFDYEQIRDLQLLVTASDSGD 539

Query: 542 PPLHANTSLHVFVLDENDNAPAVLHPRPDWEHSAPQRL-PRSAPPGSLVTKVTAVDADAG 600
           PPL +N SL +FVLD+NDNAP +L+P    + S    L PRSA  G LVTKV AVD D+G
Sbjct: 540 PPLSSNMSLSLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAERGYLVTKVVAVDRDSG 599

Query: 601 HNAWLSYSLLPQSTAPGLFLVSTHTGEVRTARALLEDDSDTQQVVVLVRDNGDPSLSSTA 660
            NAWLSY LL +++ PGLF V  HTGEVRTARALL+ D+  Q +VV V+D+G P LS+T 
Sbjct: 600 QNAWLSYRLL-KASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATV 658

Query: 661 TVLLVLEDEDPEEMPKSSDFLIH-PPERSDLTLYLIVALATVSLLSLVTFTFLSAKCL-- 717
           T+ + + D  PE + +         P  S LTLYL+VA+A +S + L     L    L  
Sbjct: 659 TLTVAVADSIPEVLTELGSLKPSVDPNDSSLTLYLVVAVAAISCVFLAFVAVLLGLRLRR 718

Query: 718 --QGNADGDGGGGQCCRRQDSPSPDF--YKQSSPNLQVSSDGTLKYMEVTLRPTDSQSHC 773
             +     D GG    R    P+  F   ++    LQ  S       EV+L     +SH 
Sbjct: 719 WHKSRLLQDSGG----RLVGVPASHFVGVEEVQAFLQTYS------QEVSLTADSRKSH- 767

Query: 774 YRTCFSPASDGSDFTFLRPLSVQQPTALALEPDAIRSRSNTLRERSQQAPPNTDWRFSQA 833
                 P  + +D   +     ++  +L    D    ++    +  QQAPPNTDWRFSQA
Sbjct: 768 ---LIFPQPNYADM-LISQEGCEKNDSLLTSVDFHEYKNEA--DHGQQAPPNTDWRFSQA 821

Query: 834 QRPGTSGSQNGDDTGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGP 893
           QRPGTSGSQNGDDTGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGP
Sbjct: 822 QRPGTSGSQNGDDTGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGP 881

Query: 894 QFTLQHVPDYRQNVYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK 944
           QFTLQHVPDYRQNVYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK
Sbjct: 882 QFTLQHVPDYRQNVYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK 932


>gi|11056063 protocadherin gamma subfamily A, 7 isoform 1 precursor
           [Homo sapiens]
          Length = 932

 Score =  831 bits (2147), Expect = 0.0
 Identities = 466/940 (49%), Positives = 611/940 (65%), Gaps = 50/940 (5%)

Query: 24  WGWVSGQLRYSVVEESEPGTLVGNVAQDLGLKMTDLLSRRLQLGSEENGRYFSLSLMSGA 83
           W   +G++ YSV EE++ G+ VG++A+DLGL+  +L  R +++ S    + F+L+  SG+
Sbjct: 24  WEAWAGRILYSVSEETDKGSFVGDIAKDLGLEPRELAERGVRIISRGRTQLFALNQRSGS 83

Query: 84  LAVNQKIDRESLCGASTSCLLPVQVVTEHPLELIRVEVEILDLNDNSPSFATPEREMRIS 143
           L    +IDRE +C  S  CL+   ++ E  + L  ++VEI+D+NDN P F T E  ++I 
Sbjct: 84  LVTAGRIDREEICAQSARCLVNFNILMEDKMNLYPIDVEIIDINDNVPRFLTEEINVKIM 143

Query: 144 ESAASGARFPLDSAQDPDVGTNTVSFYTLSPNSHFSLNVKTLKDGKPFPELVLEQQLDRE 203
           E+ A G RFPL  A DPDVGTN++  Y LSPN HFSL V++  D   +PELVLE+ LDRE
Sbjct: 144 ENTAPGVRFPLSEAGDPDVGTNSLQSYQLSPNRHFSLAVQSGDDETKYPELVLERVLDRE 203

Query: 204 AQARHQLVLTAVDGGTPARSGTTLISVIVLDINDNAPTFQSSVLRVGIPENAPIGTLLLR 263
            +  H LVLTA DGG P RS T  I V V+D+ND+ P F     +V +PEN P+GT LL 
Sbjct: 204 EERVHHLVLTASDGGDPPRSSTAHIQVTVVDVNDHTPVFSLPQYQVTVPENVPVGTRLLT 263

Query: 264 LNATDPDEGTNGQLDYSFGDHTSEAVRNLFGLDPSSGAIHVLGPIDFEESRFYEIHARAR 323
           ++A D DEG NG++ YSF   T + +  +F L+  +G I  L  +D+EE+ FYE+  +A+
Sbjct: 264 VHAIDLDEGVNGEVTYSFRKITPK-LPKMFHLNSLTGEISTLEGLDYEETAFYEMEVQAQ 322

Query: 324 DQGQPAMEGHCVIQVDVGDVNDNAPEVLLASLANPVLESTPVGTVVGLFNVRDRDSGRNG 383
           D   P       + + V DVNDNAPEV + SL++ + E TP+GTV+ LF ++DRDSG+NG
Sbjct: 323 D--GPGSLTKAKVLITVLDVNDNAPEVTMTSLSSSIPEDTPLGTVIALFYLQDRDSGKNG 380

Query: 384 EVSLDISPDLPFQIKPS-ENHYSLLTSQPLDREATSHYIIELLASDAGSPSLHKHLTIRL 442
           EV+  I  +LPF+++ S +N+Y L+T++ LDRE  S Y I L A+D G+P L +   I +
Sbjct: 381 EVTCTIPENLPFKLEKSIDNYYRLVTTKNLDRETLSLYNITLKATDGGTPPLSRETHIFM 440

Query: 443 NISDVNDNAPRFNQQLYTAYILENRPPGSLLCTVAASDPDTGDNARLTYSIVGNQVQGAP 502
            ++D NDN P F    Y+ YI EN P G+ +  V A D D+ DNA++TYS+  + +QGAP
Sbjct: 441 QVADTNDNPPTFPHSSYSVYIAENNPRGASIFLVTAQDHDSEDNAQITYSLAEDTIQGAP 500

Query: 503 ASSFVYVNPEDGRIFAQRTFDYELLQMLQIVVGVRDSGSPPLHANTSLHVFVLDENDNAP 562
            SS+V +N + G ++A ++FDYE L+ LQ+ V   DSG PPL +N SL +FVLD+NDN P
Sbjct: 501 VSSYVSINSDTGVLYALQSFDYEQLRELQLRVTAHDSGDPPLSSNMSLSLFVLDQNDNPP 560

Query: 563 AVLHPRPDWEHSAPQRL-PRSAPPGSLVTKVTAVDADAGHNAWLSYSLLPQSTAPGLFLV 621
            +L+P    + S    L PRSA PG LVTKV AVD D+G NAWLSY LL +++ PGLF V
Sbjct: 561 EILYPALPTDGSTGMELAPRSAEPGYLVTKVVAVDKDSGQNAWLSYLLL-KASEPGLFAV 619

Query: 622 STHTGEVRTARALLEDDSDTQQVVVLVRDNGDPSLSSTATVLLVLEDEDPEEMPKSSDFL 681
             +TGEVRTARALL+ D+  Q +VV V+D+G P LS+T T+ + + D  PE +       
Sbjct: 620 GLYTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADSIPEVLADLGS-- 677

Query: 682 IHP---PERSDLTLYLIVALATVS---------LLSLVTFTFLSAKCLQGNADGDGGGGQ 729
           + P   P   DLTLYL+VA+ATVS         LL+L    +  ++ LQ +  G      
Sbjct: 678 LEPSDGPYNYDLTLYLVVAVATVSCVFLAFVLVLLALRLRRWHKSRLLQASEGG------ 731

Query: 730 CCRRQDSPSPDFYKQSSPNLQVSSDGTLKYM-----EVTLRPTDSQSHCYRTCFSPASDG 784
                + P+  F         V  DG   ++     EV+L     +SH       P  + 
Sbjct: 732 ---LANVPTSHF---------VGMDGVQAFLQTYSHEVSLTADSRKSH----LIFPQPNY 775

Query: 785 SDFTFLRPLSVQQPTALALEPDAIRSRSNTLRERSQQAPPNTDWRFSQAQRPGTSGSQNG 844
            D   +   S ++  +L    D    + N      QQAPPNTDWRFSQAQRPGTSGSQNG
Sbjct: 776 VDM-LISQESCEKNDSLLTSVDFQECKENL--PSIQQAPPNTDWRFSQAQRPGTSGSQNG 832

Query: 845 DDTGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYR 904
           DDTGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYR
Sbjct: 833 DDTGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYR 892

Query: 905 QNVYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK 944
           QNVYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK
Sbjct: 893 QNVYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK 932


>gi|11128041 protocadherin gamma subfamily A, 10 isoform 1 precursor
           [Homo sapiens]
          Length = 936

 Score =  830 bits (2144), Expect = 0.0
 Identities = 468/945 (49%), Positives = 604/945 (63%), Gaps = 42/945 (4%)

Query: 15  VLCMLSLCCWGWVSGQLRYSVVEESEPGTLVGNVAQDLGLKMTDLLSRRLQLGSEENGRY 74
           +LC+     W   + Q+ YS+ EE E G+ VGN+++DLGL   +L  R +++ S    + 
Sbjct: 19  LLCLFFGIPWEAGARQISYSIPEELEKGSFVGNISKDLGLAPRELAERGVRIVSRGRTQL 78

Query: 75  FSLSLMSGALAVNQKIDRESLCGASTSCLLPVQVVTEHPLELIRVEVEILDLNDNSPSFA 134
           FSL+  SG+L    +IDRE LC  S  C++   ++ E  ++L  +E+E+ D+NDN+P F 
Sbjct: 79  FSLNPRSGSLITAGRIDREELCAQSARCVVSFNILVEDRVKLFGIEIEVTDINDNAPKFQ 138

Query: 135 TPEREMRISESAASGARFPLDSAQDPDVGTNTVSFYTLSPNSHFSLNVKTLKDGKPFPEL 194
               +++I+E+ A+G RFPL  A DPDVG N++  Y LSPN HFSL V++  +G  +PEL
Sbjct: 139 AENLDVKINENVAAGMRFPLPEAIDPDVGVNSLQSYQLSPNKHFSLRVQSRANGVKYPEL 198

Query: 195 VLEQQLDREAQARHQLVLTAVDGGTPARSGTTLISVIVLDINDNAPTFQSSVLRVGIPEN 254
           VLE  LDRE +A H LVLTA DGG P RSGT L+SV V D NDNAP F     RV +PEN
Sbjct: 199 VLEHSLDREEEAIHHLVLTASDGGDPLRSGTVLVSVTVFDANDNAPVFTLPEYRVSVPEN 258

Query: 255 APIGTLLLRLNATDPDEGTNGQLDYSFGDHTSEAVRNLFGLDPSSGAIHVLGPIDFEESR 314
            P+GT LL + ATD DEG NG++ YSF       +   F L+  +G I +   +D+EE+ 
Sbjct: 259 LPVGTQLLTVTATDRDEGANGEVTYSFRKLPDTQLLK-FQLNKYTGEIKISENLDYEETG 317

Query: 315 FYEIHARARDQGQPAMEGHCVIQVDVGDVNDNAPEVLLASLANPVLESTPVGTVVGLFNV 374
           FYEI  +A D G  A      + + V DVNDN+PE+ + SL +PV E +P+GTVV L NV
Sbjct: 318 FYEIEIQAEDGG--AYLATAKVLITVEDVNDNSPELTITSLFSPVTEDSPLGTVVALLNV 375

Query: 375 RDRDSGRNGEVSLDISPDLPFQIKPS-ENHYSLLTSQPLDREATSHYIIELLASDAGSPS 433
            D DS +NG+V+  I   LPF+++ S +++Y L+  + LDRE  S Y I + A+D GSP 
Sbjct: 376 HDLDSEQNGQVTCSILAYLPFKLEKSIDSYYRLVIHRALDREQVSSYNITVTATDGGSPP 435

Query: 434 LHKHLTIRLNISDVNDNAPRFNQQLYTAYILENRPPGSLLCTVAASDPDTGDNARLTYSI 493
           L       L ++D+NDN P F+Q  Y  YI EN   G+ + +V A DPD+ +NA++ YS+
Sbjct: 436 LSTEAHFMLQVADINDNPPTFSQVSYFTYIPENNARGASIFSVTALDPDSKENAQIIYSL 495

Query: 494 VGNQVQGAPASSFVYVNPEDGRIFAQRTFDYELLQMLQIVVGVRDSGSPPLHANTSLHVF 553
             + +QG P SS++ +N + G ++A R+FDYE    LQ+ V   DSG PPL +N SL +F
Sbjct: 496 AEDTIQGVPLSSYISINSDTGVLYALRSFDYEQFHELQMQVTASDSGDPPLSSNVSLSLF 555

Query: 554 VLDENDNAPAVLHPRPDWEHSAPQRL-PRSAPPGSLVTKVTAVDADAGHNAWLSYSLLPQ 612
           VLD+NDNAP +L+P    + S    L PRSA PG LVTKV AVD D+G NAWLSY LL +
Sbjct: 556 VLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSYRLL-K 614

Query: 613 STAPGLFLVSTHTGEVRTARALLEDDSDTQQVVVLVRDNGDPSLSSTATVLLVLEDEDPE 672
           ++ PGLF V  HTGEVRTARALL+ D+  Q +VV V+D+G P LS+T T+ + + D  P+
Sbjct: 615 ASEPGLFAVGEHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADSIPQ 674

Query: 673 EMPKSSDFLIHP-PERSDLTLYLIVALATVSLLSLVTFTFLSAKCLQG-------NADGD 724
            +     F      E SDLTLYL+VA+A VS + L     L A  L+         A G 
Sbjct: 675 VLADLGSFESPANSETSDLTLYLVVAVAAVSCVFLAFVIVLLAHRLRRWHKSRLLQASGG 734

Query: 725 GGGGQCCRRQDSPSPDFYKQSSPNLQVSSDGTLKYM-----EVTLRPTDSQSHCYRTCFS 779
           G  G                 S +  V  DG   ++     EV+L     +SH       
Sbjct: 735 GLTG----------------VSGSHFVGVDGVRAFLQTYSHEVSLTADSRKSH----LIF 774

Query: 780 PASDGSDFTFLRPLSVQQPTALALEPDAIRSRSNTLRERSQQAPPNTDWRFSQAQRPGTS 839
           P  + +D T +   S ++   L+L  D+     +T      QAPPNTDWRFSQAQRPGTS
Sbjct: 775 PQPNYAD-TLISQESCEKNDPLSLLDDSKFPIEDT--PLVPQAPPNTDWRFSQAQRPGTS 831

Query: 840 GSQNGDDTGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQH 899
           GSQNGDDTGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQH
Sbjct: 832 GSQNGDDTGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQH 891

Query: 900 VPDYRQNVYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK 944
           VPDYRQNVYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK
Sbjct: 892 VPDYRQNVYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK 936


>gi|11128027 protocadherin gamma subfamily B, 7 isoform 1 precursor
           [Homo sapiens]
          Length = 929

 Score =  828 bits (2140), Expect = 0.0
 Identities = 465/948 (49%), Positives = 603/948 (63%), Gaps = 42/948 (4%)

Query: 10  AGKWQVLCMLSL-CCWGWVSGQLRYSVVEESEPGTLVGNVAQDLGLKMTDLLSRRLQLGS 68
           AG  QVL  L L   +  +   +RYS+ EE   G++VGN+A+DLGL + D+ +R L++ +
Sbjct: 11  AGPRQVLFPLLLPLFYPTLCEPIRYSIPEELAKGSVVGNLAKDLGLSVLDVSARELRVSA 70

Query: 69  EENGRYFSLSLMSGALAVNQKIDRESLCGASTSCLLPVQVVTEHPLELIRVEVEILDLND 128
           E+   +FS+   SG L V  +IDRE +C     C L ++ V E+PL +  V V I D+ND
Sbjct: 71  EK--LHFSVDAQSGDLLVKDRIDREQICKERRRCELQLEAVVENPLNIFHVIVVIEDVND 128

Query: 129 NSPSFATPEREMRISESAASGARFPLDSAQDPDVGTNTVSFYTLSPNSHFSLNVKTLKDG 188
           ++P F   E  + ISES + G    L+SA+DPD+  N++S Y LSPN +FSL  K   DG
Sbjct: 129 HAPQFRKDEINLEISESVSLGMGTILESAEDPDISMNSLSKYQLSPNEYFSLVEKDNPDG 188

Query: 189 KPFPELVLEQQLDREAQARHQLVLTAVDGGTPARSGTTLISVIVLDINDNAPTFQSSVLR 248
             +PELVL++ LDRE Q+ H LVLTA+DGG P RSGT  I ++V+D NDN P F   V R
Sbjct: 189 GKYPELVLQKTLDRETQSAHHLVLTALDGGDPPRSGTAQIRILVIDANDNPPVFSQDVYR 248

Query: 249 VGIPENAPIGTLLLRLNATDPDEGTNGQLDYSFGDHTSEAVRNLFGLDPSSGAIHVLGPI 308
           V + E+ P GT +LR+ ATD DEG N ++ YSF     +A +++F LD ++G I    P+
Sbjct: 249 VSLREDVPPGTSILRVKATDQDEGINSEITYSFFGVADKA-QHVFSLDYTTGNILTQQPL 307

Query: 309 DFEESRFYEIHARARDQGQPAMEGHCVIQVDVGDVNDNAPEVLLASLANPVLESTPVGTV 368
           DFEE   Y I+  A+D+G  ++   C + V+V D NDN+PE+++ SL++ ++E +P G V
Sbjct: 308 DFEEVERYTINIEAKDRG--SLSTRCKVIVEVVDENDNSPEIIITSLSDQIMEDSPPGVV 365

Query: 369 VGLFNVRDRDSGRNGEVSLDISPDLPFQI-KPSENHYSLLTSQPLDREATSHYIIELLAS 427
           V LF  RD+DSG NGEV   +S  +PF+I   S N+Y L+T + LDRE T  Y + + A+
Sbjct: 366 VALFKTRDQDSGENGEVRCSLSRGVPFKIHSSSNNYYKLVTDEALDREQTPEYNVTIAAT 425

Query: 428 DAGSPSLHKHLTIRLNISDVNDNAPRFNQQLYTAYILENRPPGSLLCTVAASDPDTGDNA 487
           D G P L    TI L+I+DVNDNAP F Q  Y  ++ EN  PG+ +  V+ASDPD G N 
Sbjct: 426 DRGKPPLSSSKTITLHITDVNDNAPVFGQSAYLVHVPENNQPGASIAQVSASDPDFGLNG 485

Query: 488 RLTYSIVGNQVQGAPASSFVYVNPEDGRIFAQRTFDYELLQMLQIVVGVRDSGSPPLHAN 547
           R++YS++ + ++    SS+V V+ + G +FAQR FD+E L+  ++ +  RD GSP L AN
Sbjct: 486 RVSYSLIASDLESRTLSSYVSVSAQSGVVFAQRAFDHEQLRTFELTLQARDQGSPALSAN 545

Query: 548 TSLHVFVLDENDNAPAVLHPRPDWEHSAP-QRLPRSAPPGSLVTKVTAVDADAGHNAWLS 606
            SL V V D NDNAP VL+P    + SA    +PR+A PG LVTKV AVDAD+GHNAWLS
Sbjct: 546 VSLRVLVGDRNDNAPRVLYPALGPDGSALFDTVPRAAQPGYLVTKVVAVDADSGHNAWLS 605

Query: 607 YSLLPQSTAPGLFLVSTHTGEVRTARALLEDDSDTQQVVVLVRDNGDPSLSSTATVLLVL 666
           Y ++ Q++ PGLF +   TGEVR  RAL + DS  Q+++V VRD G P LS+TAT+ LV 
Sbjct: 606 YHVV-QASEPGLFSLGLRTGEVRMVRALGDKDSVRQRLLVAVRDGGQPPLSATATLHLVF 664

Query: 667 EDEDPEEMPKSSDFLIHPPERSDLTLYLIVALATVSLLSLVTFTFLSAKCLQGNAD---G 723
            D   E +P  SD       ++++  YL+VALA +S+L L+      A  L+ +     G
Sbjct: 665 ADSLQEVLPDFSDHPTPSDSQAEMQFYLVVALALISVLFLLAVILAIALRLRQSFSPTAG 724

Query: 724 DGGGGQCCRRQDSPSPDFYKQSSPNLQVSSDGTLKYMEVTLRPTDSQSHCYRTCFSPASD 783
           D      C +     P  Y          S+GTL Y              Y  C      
Sbjct: 725 DCFESVLCSKSGPVGPPNY----------SEGTLPY-------------AYNFCVPGDQM 761

Query: 784 GSDFTFLRPLSVQQPTALALEPDAIRSRSNTL-------RERSQQAPPNTDWRFSQAQRP 836
             +F F   +     T   L  D++   S          +   QQAPPNTDWRFSQAQRP
Sbjct: 762 NPEFNFFTSVDHCPATQDNLNKDSMLLASILTPSVEADKKILKQQAPPNTDWRFSQAQRP 821

Query: 837 GTSGSQNGDDTGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFT 896
           GTSGSQNGDDTGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFT
Sbjct: 822 GTSGSQNGDDTGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFT 881

Query: 897 LQHVPDYRQNVYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK 944
           LQHVPDYRQNVYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK
Sbjct: 882 LQHVPDYRQNVYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK 929


>gi|13470082 protocadherin gamma subfamily B, 4 isoform 1 precursor
           [Homo sapiens]
          Length = 923

 Score =  821 bits (2121), Expect = 0.0
 Identities = 469/937 (50%), Positives = 596/937 (63%), Gaps = 40/937 (4%)

Query: 16  LCMLSLCCWGWVSGQLRYSVVEESEPGTLVGNVAQDLGLKMTDLLSRRLQLGSEENGRYF 75
           L +LSL C   +  Q+RY + EE   G++VGN+A DLG  + +L +R+L++ SE+   YF
Sbjct: 19  LFLLSLFCPA-LCEQIRYRIPEEMPKGSVVGNLATDLGFSVQELPTRKLRVSSEKP--YF 75

Query: 76  SLSLMSGALAVNQKIDRESLCGASTSCLLPVQVVTEHPLELIRVEVEILDLNDNSPSFAT 135
           ++S  SG L V+ ++DRE +CG   +C L  + V E+PL    V VEI D+ND++P F  
Sbjct: 76  TVSAESGELLVSSRLDREEICGKKPACALEFEAVAENPLNFYHVNVEIEDINDHTPKFTQ 135

Query: 136 PEREMRISESAASGARFPLDSAQDPDVGTNTVSFYTLSPNSHFSLNVKTLKDGKPFPELV 195
              E++ISESA  G RF L SA D D+G+NT+  Y LSP+ HFSL  K   DG  +PE+V
Sbjct: 136 NSFELQISESAQPGTRFILGSAHDADIGSNTLQNYQLSPSDHFSLINKEKSDGSKYPEMV 195

Query: 196 LEQQLDREAQARHQLVLTAVDGGTPARSGTTLISVIVLDINDNAPTFQSSVLRVGIPENA 255
           L+  LDRE Q  + L LTA+D G P  S T  I V+V D NDNAP F   V RV + EN 
Sbjct: 196 LKTPLDREKQKSYHLTLTALDFGAPPLSSTAQIHVLVTDANDNAPVFSQDVYRVSLSENV 255

Query: 256 PIGTLLLRLNATDPDEGTNGQLDYSFGDHTSEAVRNLFGLDPSSGAIHVLGPIDFEESRF 315
             GT +L++ ATD DEG N ++ +SF +  S+  +  F L+ ++G I VL  +DFEE + 
Sbjct: 256 YPGTTVLQVTATDQDEGVNAEITFSFSE-ASQITQ--FDLNSNTGEITVLNTLDFEEVKE 312

Query: 316 YEIHARARDQGQPAMEGHCVIQVDVGDVNDNAPEVLLASLANPVLESTPVGTVVGLFNVR 375
           Y I   ARD G   M   C ++V+V D NDNAPEV+  SL N ++E   +GT + L  VR
Sbjct: 313 YSIVLEARDGG--GMIAQCTVEVEVIDENDNAPEVIFQSLPNLIMEDAELGTHIALLKVR 370

Query: 376 DRDSGRNGEVSLDISPDLPFQI-KPSENHYSLLTSQPLDREATSHYIIELLASDAGSPSL 434
           D+DS  NGEV+  +  D+PF+I   S N Y L+T   LDRE    Y I + A+D G P L
Sbjct: 371 DKDSRHNGEVTCKLEGDVPFKILTSSRNTYKLVTDAVLDREQNPEYNITVTATDRGKPPL 430

Query: 435 HKHLTIRLNISDVNDNAPRFNQQLYTAYILENRPPGSLLCTVAASDPDTGDNARLTYSIV 494
               +I L+I DVNDNAP F+Q  Y  ++ EN PPG+ +  V ASDPD G N +++Y I+
Sbjct: 431 SSSSSITLHIGDVNDNAPVFSQSSYIVHVAENNPPGASISQVRASDPDLGPNGQVSYCIM 490

Query: 495 GNQVQGAPASSFVYVNPEDGRIFAQRTFDYELLQMLQIVVGVRDSGSPPLHANTSLHVFV 554
            + ++    SS+V ++ E G +FAQR FD+E L+  ++ +  RD GSP L AN SL V V
Sbjct: 491 ASDLEQRELSSYVSISAESGVVFAQRAFDHEQLRAFELTLQARDQGSPALSANVSLRVLV 550

Query: 555 LDENDNAPAVLHPRPDWEHSAP-QRLPRSAPPGSLVTKVTAVDADAGHNAWLSYSLLPQS 613
            D NDNAP VL+P    + SA    +P +A PG LVTKV AVDAD+GHNAWLSY +L Q+
Sbjct: 551 DDRNDNAPRVLYPALGPDGSALFDMVPHAAEPGYLVTKVVAVDADSGHNAWLSYHVL-QA 609

Query: 614 TAPGLFLVSTHTGEVRTARALLEDDSDTQQVVVLVRDNGDPSLSSTATVLLVLEDEDPEE 673
           + PGLF +   TGEVRTARAL + D+  Q+++V VRD G P LS+TAT+ LV  D   E 
Sbjct: 610 SEPGLFSLGLRTGEVRTARALGDRDAVRQRLLVAVRDGGQPPLSATATLHLVFADSLQEV 669

Query: 674 MPKSSDFLIHPPERSDLTLYLIVALATVSLLSLVTFTFLSAKCLQGNADGDGGGGQCCRR 733
           +P  +D       +++L  YL+VALA +S+L LV      A                 R 
Sbjct: 670 LPDITDRPDPSDLQAELQFYLVVALALISVLFLVAMILAIA----------------LRL 713

Query: 734 QDSPSPDFYKQSSPNLQVSSDGTL--KYMEVTLRPTDSQSHCYRTCFSPASDGSDFTFLR 791
           + S SP  +    P L V S+  +   Y E TL       + Y  C +     ++F FL+
Sbjct: 714 RRSSSPASWSCFQPGLCVKSESVVPPNYSEGTL------PYSYNLCVAHTGK-TEFNFLK 766

Query: 792 ---PLSVQQPTALALEPDAIRSRSNTLRERS-QQAPPNTDWRFSQAQRPGTSGSQNGDDT 847
               LS  Q         A+    N+    S QQAPPNTDWRFSQAQRPGTSGSQNGDDT
Sbjct: 767 CSEQLSSGQDILCGDSSGALFPLCNSSELTSHQQAPPNTDWRFSQAQRPGTSGSQNGDDT 826

Query: 848 GTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNV 907
           GTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNV
Sbjct: 827 GTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNV 886

Query: 908 YIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK 944
           YIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK
Sbjct: 887 YIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK 923


>gi|11128029 protocadherin gamma subfamily B, 6 isoform 1 precursor
           [Homo sapiens]
          Length = 930

 Score =  815 bits (2105), Expect = 0.0
 Identities = 460/952 (48%), Positives = 603/952 (63%), Gaps = 49/952 (5%)

Query: 10  AGKWQVLCMLSL-CCWGWVSGQLRYSVVEESEPGTLVGNVAQDLGLKMTDLLSRRLQLGS 68
           AG  QVL  L L   +  +S  +RYS+ EE   G++VGN+A+DLGL + D+ +R+L++ +
Sbjct: 11  AGPRQVLFPLLLPLFYPTLSEPIRYSIPEELAKGSVVGNLAKDLGLSVLDVSARKLRVSA 70

Query: 69  EENGRYFSLSLMSGALAVNQKIDRESLCGASTSCLLPVQVVTEHPLELIRVEVEILDLND 128
           E+   +FS+   SG L V  +IDRE +C     C L ++ V E+PL +  V V I D+ND
Sbjct: 71  EK--LHFSVDAESGDLLVKNRIDREQICKERRRCELQLEAVVENPLNIFHVIVVIEDVND 128

Query: 129 NSPSFATPEREMRISESAASGARFPLDSAQDPDVGTNTVSFYTLSPNSHFSLNVKTLKDG 188
           ++P F   E  + I ESA++G R  LD A DPD+  N++  Y ++ N +FSL V+   DG
Sbjct: 129 HAPQFDKKEIHLEIFESASAGTRLSLDPATDPDININSIKDYKINSNPYFSLMVRVNSDG 188

Query: 189 KPFPELVLEQQLDREAQARHQLVLTAVDGGTPARSGTTLISVIVLDINDNAPTFQSSVLR 248
             +PEL LE+ LDRE Q  H L+LTA+DGG P RS T  I + V D NDN P F     R
Sbjct: 189 GKYPELSLEKLLDREEQRSHSLILTALDGGDPPRSATAHIEISVKDTNDNPPVFSRDEYR 248

Query: 249 VGIPENAPIGTLLLRLNATDPDEGTNGQLDYSFGDHTSEAVRNLFGLDPSSGAIHVLGPI 308
           + + EN P G+ +L++ ATD DEG N +++Y F   T+++ +++F LD  +G I      
Sbjct: 249 ISLSENLPPGSPVLQVTATDQDEGVNAEINYYFRS-TAQSTKHMFSLDEKTGMIKNNQSF 307

Query: 309 DFEESRFYEIHARARDQGQPAMEGHCVIQVDVGDVNDNAPEVLLASLANPVLESTPVGTV 368
           DFE+   Y +   A+D G   +   C + +++ D NDN+PE+++ SL++ +LE++P G V
Sbjct: 308 DFEDVERYTMEVEAKDGG--GLSTQCKVIIEILDENDNSPEIIITSLSDQILENSPPGMV 365

Query: 369 VGLFNVRDRDSGRNGEVSLDISPDLPFQI-KPSENHYSLLTSQPLDREATSHYIIELLAS 427
           V LF  RD D G NGEV  +I  D+PF+I   S N+Y L+T   LDRE T  Y + ++A+
Sbjct: 366 VALFKTRDLDFGGNGEVRCNIETDIPFKIYSSSNNYYKLVTDGALDREQTPEYNVTIVAT 425

Query: 428 DAGSPSLHKHLTIRLNISDVNDNAPRFNQQLYTAYILENRPPGSLLCTVAASDPDTGDNA 487
           D G P L    +I L ++D+NDNAP F+Q  Y  ++ EN PPG+ +  V+ASDPD G N 
Sbjct: 426 DRGKPPLSSSRSITLYVADINDNAPVFDQTSYVVHVAENNPPGASIAQVSASDPDLGLNG 485

Query: 488 RLTYSIVGNQVQGAPASSFVYVNPEDGRIFAQRTFDYELLQMLQIVVGVRDSGSPPLHAN 547
            ++YSIV + ++    SS+V V+ + G +FAQR FD+E L+   + +  RD GSP L AN
Sbjct: 486 HISYSIVASDLEPLAVSSYVSVSAQSGVVFAQRAFDHEQLRAFALTLQARDHGSPTLSAN 545

Query: 548 TSLHVFVLDENDNAPAVLHPRPDWEHSAP-QRLPRSAPPGSLVTKVTAVDADAGHNAWLS 606
            SL V V D NDNAP VL+P    + SA    +PRSA PG LVTKV AVDAD+GHNAWLS
Sbjct: 546 VSLRVLVGDRNDNAPRVLYPALGPDGSAFFDMVPRSAEPGYLVTKVVAVDADSGHNAWLS 605

Query: 607 YSLLPQSTAPGLFLVSTHTGEVRTARALLEDDSDTQQVVVLVRDNGDPSLSSTATVLLVL 666
           Y +L Q++ PGLF +   TGEVRTARAL + D+  Q+++V VRD G P LS+TAT+ LV 
Sbjct: 606 YHVL-QASEPGLFSLGLRTGEVRTARALGDRDAARQRLLVAVRDGGQPPLSATATLHLVF 664

Query: 667 EDEDPEEMPKSSDFLIHPPERSDLTLYLIVALATVSLLSLVTFTFLSAKCLQGNADGDGG 726
            D   E +P  SD  +    +++L  YL+VALA +S+L L+      A            
Sbjct: 665 ADNLQEILPDLSDRPVLSDPQAELQFYLVVALALISVLFLLAVILAIA------------ 712

Query: 727 GGQCCRRQDSPSPDFYKQSSPNLQVSSDGTL--KYMEVTLRPTDSQSHCYRTCFSPASDG 784
                R + S SP  +    P L V S   +   Y E TL       + Y  C +     
Sbjct: 713 ----LRLRRSLSPATWDCFHPGLCVKSGPVVPPNYSEGTL------PYSYNLCIAHTGT- 761

Query: 785 SDFTFLR---PLSVQQPTALALEPDAI---------RSRSNTLRERSQQAPPNTDWRFSQ 832
            +F FL+   PL   +    ++ P A+          S   TL   + QAPPNTDWRFSQ
Sbjct: 762 KEFNFLKCSVPLHSNEDMVCSVSPGALIPPHGGEDLTSHPETL---TSQAPPNTDWRFSQ 818

Query: 833 AQRPGTSGSQNGDDTGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYG 892
           AQRPGTSGSQNGDDTGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYG
Sbjct: 819 AQRPGTSGSQNGDDTGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYG 878

Query: 893 PQFTLQHVPDYRQNVYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK 944
           PQFTLQHVPDYRQNVYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK
Sbjct: 879 PQFTLQHVPDYRQNVYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK 930


>gi|11128031 protocadherin gamma subfamily B, 5 isoform 1 precursor
           [Homo sapiens]
          Length = 923

 Score =  814 bits (2103), Expect = 0.0
 Identities = 459/939 (48%), Positives = 599/939 (63%), Gaps = 44/939 (4%)

Query: 16  LCMLSLCCWGWVSGQLRYSVVEESEPGTLVGNVAQDLGLKMTDLLSRRLQLGSEENGRYF 75
           L +LSL C   +  Q+RY + EE   G++VGN+A DLG  + +L +R+L++ SE+   YF
Sbjct: 19  LFLLSLFCPA-LCEQIRYRIPEEMPKGSVVGNLATDLGFSVQELPTRKLRVSSEKP--YF 75

Query: 76  SLSLMSGALAVNQKIDRESLCGASTSCLLPVQVVTEHPLELIRVEVEILDLNDNSPSFAT 135
           ++S  SG L V+ ++DRE +CG   +C L  + V E+PL    V VEI D+ND++P F  
Sbjct: 76  TVSAESGELLVSSRLDREEICGKKPACALEFEAVAENPLNFYHVNVEIEDINDHTPKFTQ 135

Query: 136 PEREMRISESAASGARFPLDSAQDPDVGTNTVSFYTLSPNSHFSLNVKTLKDGKPFPELV 195
              E++ISESA  G RF L+ A+D D+G N++  Y LS N  FSL +K  +DG  +PEL 
Sbjct: 136 NSFELQISESAQPGTRFILEVAEDADIGLNSLQKYKLSLNPSFSLIIKEKQDGSKYPELA 195

Query: 196 LEQQLDREAQARHQLVLTAVDGGTPARSGTTLISVIVLDINDNAPTFQSSVLRVGIPENA 255
           LE+ LDRE Q+ H+LVLTA+DGG P  SGTT + + V D NDN P F   V RV + EN 
Sbjct: 196 LEKTLDREQQSYHRLVLTALDGGHPPLSGTTELRIQVTDANDNPPVFNRDVYRVSLRENV 255

Query: 256 PIGTLLLRLNATDPDEGTNGQLDYSFGDHTSEAVRNLFGLDPSSGAIHVLGPIDFEESRF 315
           P GT +L+++ATD DEG N ++ YSF          +F L+  SG I     +DFEE++ 
Sbjct: 256 PPGTTVLQVSATDQDEGINSEITYSF-----YRTGQIFSLNSKSGEITTQKKLDFEETKE 310

Query: 316 YEIHARARDQGQPAMEGHCVIQVDVGDVNDNAPEVLLASLANPVLESTPVGTVVGLFNVR 375
           Y +    RD G   +   C +++++ D NDN+PEV   SL   +LE+   GT++ L  + 
Sbjct: 311 YSMVVEGRDGG--GLVAQCTVEINIQDENDNSPEVTFHSLLEMILENAVPGTLIALIKIH 368

Query: 376 DRDSGRNGEVSLDISPDLPFQI-KPSENHYSLLTSQPLDREATSHYIIELLASDAGSPSL 434
           D+DSG NGEV+  +  ++PF+I   S+N Y L+T   LDRE T  Y + + A+D G P L
Sbjct: 369 DQDSGENGEVNCQLQGEVPFKIISSSKNSYKLVTDGTLDREQTPEYNVTITATDRGKPPL 428

Query: 435 HKHLTIRLNISDVNDNAPRFNQQLYTAYILENRPPGSLLCTVAASDPDTGDNARLTYSIV 494
              +++ L+I DVNDNAP F+Q  Y   + EN PPG+ +  V ASD D G N +++YSI+
Sbjct: 429 SSSISVILHIRDVNDNAPVFHQASYLVSVPENNPPGASIAQVCASDLDLGLNGQVSYSIM 488

Query: 495 GNQVQGAPASSFVYVNPEDGRIFAQRTFDYELLQMLQIVVGVRDSGSPPLHANTSLHVFV 554
            + ++    +S+V ++ + G +FAQR FDYE L+  ++ +  RD GSP L AN SL V V
Sbjct: 489 ASDLEPLALASYVSMSAQSGVVFAQRAFDYEQLRTFELTLQARDQGSPALSANVSLRVLV 548

Query: 555 LDENDNAPAVLHPRPDWEHSAP-QRLPRSAPPGSLVTKVTAVDADAGHNAWLSYSLLPQS 613
            D NDNAP VL+P    + SA    +PR+A PG LVTKV AVDAD+GHNAWLSY +L Q+
Sbjct: 549 GDRNDNAPRVLYPALGPDGSALFDMVPRAAEPGYLVTKVVAVDADSGHNAWLSYHVL-QA 607

Query: 614 TAPGLFLVSTHTGEVRTARALLEDDSDTQQVVVLVRDNGDPSLSSTATVLLVLEDEDPEE 673
           + PGLF +   TGEVRTARAL + D+  Q+++V VRD G P LS+TAT+ LV  D   E 
Sbjct: 608 SEPGLFSLGLRTGEVRTARALGDRDAARQRLLVAVRDGGQPPLSATATLHLVFADSLQEV 667

Query: 674 MPKSSDFLIHPPERSDLTLYLIVALATVSLLSLVTFTFLSAKCLQGNADGDGGGGQCCRR 733
           +P  +D  +    +++L  YL+VALA +S+L L+      A  L              RR
Sbjct: 668 LPDITDRPVPSDPQAELQFYLVVALALISVLFLLAVILAVALRL--------------RR 713

Query: 734 QDSPS------PDFYKQSSPNLQVS-SDGTLKYM-EVTLRPTDSQSHCYRTCFSPASDGS 785
             SP+      P    +S P +  + S GTL Y   + +  T      +  C    S G 
Sbjct: 714 SSSPAAWSCFQPGLCVKSGPVVPPNYSQGTLPYSYNLCVAHTGKTEFNFLKCSEQLSSGQ 773

Query: 786 DFTFLRPLSVQQPTALALEPDAIRSRSNTLRERSQQAPPNTDWRFSQAQRPGTSGSQNGD 845
           D        +   ++ AL P    S S +  E   QAPPNTDWRFSQAQRPGTSGSQNGD
Sbjct: 774 DI-------LCGDSSGALFPLCNSSESTSHPEL--QAPPNTDWRFSQAQRPGTSGSQNGD 824

Query: 846 DTGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQ 905
           DTGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQ
Sbjct: 825 DTGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQ 884

Query: 906 NVYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK 944
           NVYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK
Sbjct: 885 NVYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK 923


>gi|14277675 protocadherin gamma subfamily C, 3 isoform 1 precursor
           [Homo sapiens]
          Length = 934

 Score =  812 bits (2097), Expect = 0.0
 Identities = 438/932 (46%), Positives = 587/932 (62%), Gaps = 48/932 (5%)

Query: 31  LRYSVVEESEPGTLVGNVAQDLGLKMTDLLSRRLQLGSEENGRYFSLSLMSGALAVNQKI 90
           + Y + EE E G  VGNV  +LGL +  L +RR ++ S  + R+F ++  +G + VN ++
Sbjct: 33  IHYEIPEEREKGFAVGNVVANLGLDLGSLSARRFRVVSGASRRFFEVNRETGEMFVNDRL 92

Query: 91  DRESLCGASTSCLLPVQVVTEHPLELIRVEVEILDLNDNSPSFATPEREMRISESAASGA 150
           DRE LCG   SC + +++V E+PLEL  VEV I D+NDN+P+F T E ++ ISE+ A G 
Sbjct: 93  DREELCGTLPSCTVTLELVVENPLELFSVEVVIQDINDNNPAFPTQEMKLEISEAVAPGT 152

Query: 151 RFPLDSAQDPDVGTNTVSFYTLSPNSHFSLNVKTLKDGKPFPELVLEQQLDREAQARHQL 210
           RFPL+SA DPDVG+N++  Y LS N +F+L V+T +D   + ELVLE+ LDRE +   QL
Sbjct: 153 RFPLESAHDPDVGSNSLQTYELSRNEYFALRVQTREDSTKYAELVLERALDREREPSLQL 212

Query: 211 VLTAVDGGTPARSGTTLISVIVLDINDNAPTFQSSVLRVGIPENAPIGTLLLRLNATDPD 270
           VLTA+DGGTPA S +  I + VLD NDNAP F  S+ R  + E+AP GT ++++ ATD D
Sbjct: 213 VLTALDGGTPALSASLPIHIKVLDANDNAPVFNQSLYRARVLEDAPSGTRVVQVLATDLD 272

Query: 271 EGTNGQLDYSFGDHTSEAVRNLFGLDPSSGAIHVLGPIDFEESRFYEIHARARDQGQPAM 330
           EG NG++ YSFG H    VR LF LD  +G + + G +DFE+++ +EI+ +A+D+G    
Sbjct: 273 EGPNGEIIYSFGSHNRAGVRQLFALDLVTGMLTIKGRLDFEDTKLHEIYIQAKDKGANPE 332

Query: 331 EGHCVIQVDVGDVNDNAPEVLLASLANPVLESTPVGTVVGLFNVRDRDSGRNGEVSLDIS 390
             HC + V+V DVNDNAPE+ + S+ +PV E  P+GTV+ L +V D D+G NG V+ ++ 
Sbjct: 333 GAHCKVLVEVVDVNDNAPEITVTSVYSPVPEDAPLGTVIALLSVTDLDAGENGLVTCEVP 392

Query: 391 PDLPFQIKPS-ENHYSLLTSQPLDREATSHYIIELLASDAGSPSLHKHLTIRLNISDVND 449
           P LPF +  S +N+++L TS  LDRE    Y + + A DAG+PSL     +R+ +SD+ND
Sbjct: 393 PGLPFSLTSSLKNYFTLKTSADLDRETVPEYNLSITARDAGTPSLSALTIVRVQVSDIND 452

Query: 450 NAPRFNQQLYTAYILENRPPGSLLCTVAASDPDTGDNARLTYSIVGNQVQGAPASSFVYV 509
           N P+ +Q  Y  YI EN  PG+ +  ++  DPD   NARL++ ++    +      +  +
Sbjct: 453 NPPQSSQSSYDVYIEENNLPGAPILNLSVWDPDAPQNARLSFFLLEQGAETGLVGRYFTI 512

Query: 510 NPEDGRIFAQRTFDYELLQMLQIVVGVRDSGSPPLHANTSLHVFVLDENDNAPAVLHPRP 569
           N ++G + +    DYE  +  ++   + D G+P L  N S+++FV D NDNAP VL+PRP
Sbjct: 513 NRDNGIVSSLVPLDYEDRREFELTAHISDGGTPVLATNISVNIFVTDRNDNAPQVLYPRP 572

Query: 570 DWEHSAPQRLPRSAPPGSLVTKVTAVDADAGHNAWLSYSLLPQSTAPGLFLVSTHTGEVR 629
               S+ + LPR    G LV++V   DADAGHNAWLSYSLL  S    LF +  HTG++ 
Sbjct: 573 G--GSSVEMLPRGTSAGHLVSRVVGWDADAGHNAWLSYSLL-GSPNQSLFAIGLHTGQIS 629

Query: 630 TARALLEDDSDTQQVVVLVRDNGDPSLSSTATVLLVLEDEDPEEMPKSSDFLIHPPERSD 689
           TAR + + DS  Q + VL++DNG+PSLS+TAT+ + + ++ PE   +         ++ +
Sbjct: 630 TARPVQDTDSPRQTLTVLIKDNGEPSLSTTATLTVSVTEDSPEARAEFPSGSAPREQKKN 689

Query: 690 LTLYLIVALATVSLLSLVT-FTFLSAKCLQGNADGDGGGGQCCRRQDSPSPDFYKQSSPN 748
           LT YL+++L  VS+  +VT F  +  K  +     D           +P    Y+   P+
Sbjct: 690 LTFYLLLSLILVSVGFVVTVFGVIIFKVYKWKQSRD--------LYRAPVSSLYRTPGPS 741

Query: 749 LQVSSDGTLKYMEVTLRPTDSQSHCYRTCFSPASDGSDFTFLRPLSVQQPTALALEPDAI 808
           L   +          +R      H Y   +           L+      P A        
Sbjct: 742 LHADA----------VRGGLMSPHLYHQVYLTTDSRRSDPLLKKPGAASPLA-------- 783

Query: 809 RSRSNTLRE----------------RSQQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPN 852
            SR NTLR                   QQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPN
Sbjct: 784 -SRQNTLRSCDPVFYRQVLGAESAPPGQQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPN 842

Query: 853 NQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGS 912
           NQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGS
Sbjct: 843 NQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGS 902

Query: 913 NATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK 944
           NATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK
Sbjct: 903 NATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK 934


>gi|11128035 protocadherin gamma subfamily B, 2 isoform 1 precursor
           [Homo sapiens]
          Length = 931

 Score =  811 bits (2095), Expect = 0.0
 Identities = 451/928 (48%), Positives = 590/928 (63%), Gaps = 41/928 (4%)

Query: 30  QLRYSVVEESEPGTLVGNVAQDLGLKMTDLLSRRLQLGSEENGRYFSLSLMSGALAVNQK 89
           Q+RYS+ EE    ++VGN+A+DLGL + DL +R+L++ +E+   YF+++  SG L V+ +
Sbjct: 32  QIRYSIPEELAKNSVVGNLAKDLGLSVRDLPARKLRVSAEKE--YFTVNPESGDLLVSDR 89

Query: 90  IDRESLCGASTSCLLPVQVVTEHPLELIRVEVEILDLNDNSPSFATPEREMRISESAASG 149
           IDRE +CG    C+L    V E+PL +  + V + D+NDN+P F   +  ++I ES   G
Sbjct: 90  IDREQICGKQPLCVLDFDTVAENPLNIFYIAVIVQDINDNTPLFKQTKINLKIGESTKPG 149

Query: 150 ARFPLDSAQDPDVGTNTVSFYTLSPNSHFSLNVKTLKDGKPFPELVLEQQLDREAQARHQ 209
             FPLD A D DVG N++  Y L+ N +F L  K   DG+ +PEL+L+  LDRE  + HQ
Sbjct: 150 TTFPLDPALDSDVGPNSLQRYHLNDNEYFDLAEKQTPDGRKYPELILKHSLDREEHSLHQ 209

Query: 210 LVLTAVDGGTPARSGTTLISVIVLDINDNAPTFQSSVLRVGIPENAPIGTLLLRLNATDP 269
           LVLTAVDGG P +SGTT I + V D NDN P F   V RV + E+ P G  +L++ ATD 
Sbjct: 210 LVLTAVDGGDPPQSGTTQIRIKVTDANDNPPVFSQDVYRVTLREDVPPGFFVLQVTATDR 269

Query: 270 DEGTNGQLDYSFGDHTSEAVRNLFGLDPSSGAIHVLGPIDFEESRFYEIHARARDQGQPA 329
           DEG N ++ YSF  +  E V++ F L+  +G I     +DFE +  Y +   A+D G  A
Sbjct: 270 DEGINAEITYSF-HNVDEQVKHFFNLNEKTGEITTKDDLDFEIASSYTLSIEAKDPGDLA 328

Query: 330 MEGHCVIQVDVGDVNDNAPEVLLASLANPVLESTPVGTVVGLFNVRDRDSGRNGEVSLDI 389
              HC IQV++ D ND APEV++ S++ P+ E +P GTV+ L   RDRDSG NGEV   +
Sbjct: 329 --AHCSIQVEILDDNDCAPEVIVTSVSTPLPEDSPPGTVIALIKTRDRDSGENGEVYCQV 386

Query: 390 SPDLPFQIKPS-ENHYSLLTSQPLDREATSHYIIELLASDAGSPSLHKHLTIRLNISDVN 448
             +  F +K S +N+Y L+T   LDRE    Y + + A+D G P L   + + L+ISDVN
Sbjct: 387 LGNAKFILKSSSKNYYKLVTDGALDREEIPEYNLTITATDGGKPPLSSSIIVTLHISDVN 446

Query: 449 DNAPRFNQQLYTAYILENRPPGSLLCTVAASDPDTGDNARLTYSIVGNQVQGAPASSFVY 508
           DNAP F Q  Y  ++ EN PPG+ +  ++ASDPD G + +++YSIV + ++     S+V 
Sbjct: 447 DNAPVFQQTSYMVHVAENNPPGASIAQISASDPDLGPSGQVSYSIVASDLKPREILSYVS 506

Query: 509 VNPEDGRIFAQRTFDYELLQMLQIVVGVRDSGSPPLHANTSLHVFVLDENDNAPAVLHPR 568
           V+ + G +FAQR FD+E L+  ++ +  RD GSP L AN SL V V D NDNAP VL+P 
Sbjct: 507 VSAQSGVVFAQRAFDHEQLRAFELTLQARDQGSPALSANVSLRVLVGDLNDNAPRVLYPA 566

Query: 569 PDWEHSAP-QRLPRSAPPGSLVTKVTAVDADAGHNAWLSYSLLPQSTAPGLFLVSTHTGE 627
              + SA    +PR+A PG LVTKV AVDAD+GHNAWLSY +L Q++ PGLF +   TGE
Sbjct: 567 LGPDGSALFDMVPRAAEPGYLVTKVVAVDADSGHNAWLSYHVL-QASEPGLFSLGLRTGE 625

Query: 628 VRTARALLEDDSDTQQVVVLVRDNGDPSLSSTATVLLVLEDEDPEEMPKSSDFLIHPPER 687
           VRTARAL + D+  Q+++V VRD G P LS+TAT+ L+  D   E +P  SD       +
Sbjct: 626 VRTARALGDRDAARQRLLVAVRDGGQPPLSATATLHLIFADSLQEVLPDLSDRREPSDPQ 685

Query: 688 SDLTLYLIVALATVSLLSLVTFTFLSAKCLQGNADGDGGGGQCCRRQDSPSPDFYKQSSP 747
           + L  YL+VALA +S+L  +      +  L+ ++  D          D   P    +  P
Sbjct: 686 AKLQFYLVVALALISVLFFLAVILAISLRLRLSSRSDAW--------DCFQPGLSSKPGP 737

Query: 748 NLQVS-SDGTLKYMEVTLRPTDSQSHCYRTCFSPASDGSDFTFLRPLSVQQPTALALEPD 806
            +  + S+GTL Y              Y  C +  S  ++F FL  ++ +   A  L  D
Sbjct: 738 GVLPNYSEGTLPYS-------------YNLCVASQSAKTEFNFLN-ITPELVPAQDLVCD 783

Query: 807 AIRSRSNTLRERS----------QQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQFD 856
                 NT    +          +QAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQFD
Sbjct: 784 NASWEQNTNHGAAGVPFASDTILKQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQFD 843

Query: 857 TEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATL 916
           TEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATL
Sbjct: 844 TEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATL 903

Query: 917 TNAAGKRDGKAPAGGNGNKKKSGKKEKK 944
           TNAAGKRDGKAPAGGNGNKKKSGKKEKK
Sbjct: 904 TNAAGKRDGKAPAGGNGNKKKSGKKEKK 931


>gi|11056032 protocadherin gamma subfamily A, 1 isoform 1 precursor
           [Homo sapiens]
          Length = 931

 Score =  811 bits (2095), Expect = 0.0
 Identities = 455/932 (48%), Positives = 595/932 (63%), Gaps = 43/932 (4%)

Query: 28  SGQLRYSVVEESEPGTLVGNVAQDLGLKMTDLLSRRLQLGSEENGRYFSLSLMSGALAVN 87
           +G + YSV EE++ G+ VGN+A+DLGL+  +L    +++ S      F+L+  SG+L   
Sbjct: 28  AGNIHYSVPEETDKGSFVGNIAKDLGLQPQELADGGVRIVSRGRMPLFALNPRSGSLITA 87

Query: 88  QKIDRESLCGASTSCLLPVQVVTEHPLELIRVEVEILDLNDNSPSFATPEREMRISESAA 147
           ++IDRE LC  S  CL+   ++ E  ++L  VEVEI+D+NDN+P F   E E +++E   
Sbjct: 88  RRIDREELCAQSMPCLVSFNILVEDKMKLFPVEVEIIDINDNTPQFQLEELEFKMNEITT 147

Query: 148 SGARFPLDSAQDPDVGTNTVSFYTLSPNSHFSLNVKTLKDGKPFPELVLEQQLDREAQAR 207
            G R  L   QD DVG N++  Y LS N HFSL+V+   DG   PE+VL+  LDRE +A 
Sbjct: 148 PGTRVSLPFGQDLDVGMNSLQSYQLSSNPHFSLDVQQGADGPQHPEMVLQSPLDREEEAV 207

Query: 208 HQLVLTAVDGGTPARSGTTLISVIVLDINDNAPTFQSSVLRVGIPENAPIGTLLLRLNAT 267
           H L+LTA DGG P RSGT  I + V+D NDN P F  +   + +PEN P+GT LL +NAT
Sbjct: 208 HHLILTASDGGEPVRSGTLRIYIQVVDANDNPPAFTQAQYHINVPENVPLGTQLLMVNAT 267

Query: 268 DPDEGTNGQLDYSFGDHTSEAVRNLFGLDPSSGAIHVLGPIDFEESRFYEIHARARDQGQ 327
           DPDEG NG++ YSF  +    V  +F LD  +G I    P+DFEE + Y +  +A+D   
Sbjct: 268 DPDEGANGEVTYSF-HNVDHRVAQIFRLDSYTGEISNKEPLDFEEYKMYSMEVQAQDGA- 325

Query: 328 PAMEGHCVIQVDVGDVNDNAPEVLLASLANPVLESTPVGTVVGLFNVRDRDSGRNGEVSL 387
             +     + + V DVNDNAPEV + S+   V E+ P GT++ L +V D+DSG NG  + 
Sbjct: 326 -GLMAKVKVLIKVLDVNDNAPEVTITSVTTAVPENFPPGTIIALISVHDQDSGDNGYTTC 384

Query: 388 DISPDLPFQI-KPSENHYSLLTSQPLDREATSHYIIELLASDAGSPSLHKHLTIRLNISD 446
            I  +LPF++ K  +N+Y L+T + LDRE  S Y I + A D G+P+L     I L ++D
Sbjct: 385 FIPGNLPFKLEKLVDNYYRLVTERTLDRELISGYNITITAIDQGTPALSTETHISLLVTD 444

Query: 447 VNDNAPRFNQQLYTAYILENRPPGSLLCTVAASDPDTGDNARLTYSIVGNQVQGAPASSF 506
           +NDN+P F+Q  Y+AYI EN P G+ + +V A D D+ +NA++TYS++ + +QGAP S++
Sbjct: 445 INDNSPVFHQDSYSAYIPENNPRGASIFSVRAHDLDSNENAQITYSLIEDTIQGAPLSAY 504

Query: 507 VYVNPEDGRIFAQRTFDYELLQMLQIVVGVRDSGSPPLHANTSLHVFVLDENDNAPAVLH 566
           + +N + G ++A R+FDYE  + +Q+ V  RDSG PPL +N SL +F+LD+NDNAP +L+
Sbjct: 505 LSINSDTGVLYALRSFDYEQFRDMQLKVMARDSGDPPLSSNVSLSLFLLDQNDNAPEILY 564

Query: 567 PRPDWEHSAPQRL-PRSAPPGSLVTKVTAVDADAGHNAWLSYSLLPQSTAPGLFLVSTHT 625
           P    + S    L P SA PG LVTKV AVD D+G NAWLSY LL +++ PGLF V  HT
Sbjct: 565 PALPTDGSTGVELAPLSAEPGYLVTKVVAVDRDSGQNAWLSYRLL-KASEPGLFSVGLHT 623

Query: 626 GEVRTARALLEDDSDTQQVVVLVRDNGDPSLSSTATVLLVLEDEDPEEMPKSSDFLIHP- 684
           GEVRTARALL+ D+  Q +VV V+D+G P LS+T T+ + + D   + +       + P 
Sbjct: 624 GEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADRISDILADLGS--LEPS 681

Query: 685 --PERSDLTLYLIVALATVSLLSLVTFTFLSAKCLQG-----NADGDGGGGQCCRRQDSP 737
             P  SDLTLYL+VA A VS + L     L A  L+           GGG         P
Sbjct: 682 AKPNDSDLTLYLVVAAAAVSCVFLAFVIVLLAHRLRRWHKSRLLQASGGG-----LASMP 736

Query: 738 SPDFYKQSSPNLQVSSDGTLKYM-----EVTLRPTDSQSHCYRTCFSPASDGSDFTFLRP 792
              F         V  DG   ++     EV+L     +SH       P  + +D T +  
Sbjct: 737 GSHF---------VGVDGVRAFLQTYSHEVSLTADSRKSHL----IFPQPNYAD-TLISQ 782

Query: 793 LSVQQPTALALEPDAIRSRSNTLRERSQQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPN 852
            S ++   L+     +  +       SQQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPN
Sbjct: 783 ESCEKKGFLSAPQSLLEDKKEPF---SQQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPN 839

Query: 853 NQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGS 912
           NQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGS
Sbjct: 840 NQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGS 899

Query: 913 NATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK 944
           NATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK
Sbjct: 900 NATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK 931


>gi|11128033 protocadherin gamma subfamily B, 3 isoform 1 precursor
           [Homo sapiens]
          Length = 929

 Score =  809 bits (2089), Expect = 0.0
 Identities = 457/927 (49%), Positives = 588/927 (63%), Gaps = 35/927 (3%)

Query: 27  VSGQLRYSVVEESEPGTLVGNVAQDLGLKMTDLLSRRLQLGSEENGRYFSLSLMSGALAV 86
           +S  +RY++ EE + G+LVGN+A+DLG  + DL +R L++ +E+  ++F++S  +G L V
Sbjct: 29  LSEPIRYAIPEELDRGSLVGNLAKDLGFGVGDLPTRNLRVIAEK--KFFTVSPENGNLLV 86

Query: 87  NQKIDRESLCGASTSCLLPVQVVTEHPLELIRVEVEILDLNDNSPSFATPEREMRISESA 146
           + +IDRE +CG  ++C+L  ++V E PL    V V I D+NDN P+F+    E+ ISE A
Sbjct: 87  SDRIDREEICGKKSTCVLEFEMVAEKPLNFFHVTVLIQDINDNPPTFSQNITELEISELA 146

Query: 147 ASGARFPLDSAQDPDVGTNTVSFYTLSPNSHFSLNVKTLKDGKPFPELVLEQQLDREAQA 206
            +GA F L+SAQDPDVG N++  Y LSP+ HFSL  K   DG  +PELVL+  LDRE Q 
Sbjct: 147 LTGATFALESAQDPDVGVNSLQQYYLSPDPHFSLIQKENLDGSRYPELVLKAPLDREEQP 206

Query: 207 RHQLVLTAVDGGTPARSGTTLISVIVLDINDNAPTFQSSVLRVGIPENAPIGTLLLRLNA 266
            H LVLTAVDGG P+RS TT I VIV D NDN P F   + RV + EN P G+ +L++ A
Sbjct: 207 HHHLVLTAVDGGEPSRSCTTQIRVIVADANDNPPVFTQDMYRVNVAENLPAGSSVLKVMA 266

Query: 267 TDPDEGTNGQLDYSFGDHTSEAVRNLFGLDPSSGAIHVLGPIDFEESRFYEIHARARDQG 326
            D DEG N ++ Y+F +   E VR LF LD  +G +  +G +DFEE   Y I   A+D G
Sbjct: 267 IDMDEGINAEIIYAFINIGKE-VRQLFKLDSKTGELTTIGELDFEERDSYTIGVEAKDGG 325

Query: 327 QPAMEGHCVIQVDVGDVNDNAPEVLLASLANPVLESTPVGTVVGLFNVRDRDSGRNGEVS 386
                 +C +Q+D+ D NDNAPE+ LAS +  + E   +GT V L    D DSG NGE+ 
Sbjct: 326 HHT--AYCKVQIDISDENDNAPEITLASESQHIQEDAELGTAVALIKTHDLDSGFNGEIL 383

Query: 387 LDISPDLPFQI-KPSENHYSLLTSQPLDREATSHYIIELLASDAGSPSLHKHLTIRLNIS 445
             +  + PF+I + ++N Y L+T   LDRE    Y + + A+D G+P L    TI L+I 
Sbjct: 384 CQLKGNFPFKIVQDTKNTYRLVTDGALDREQIPEYNVTITATDKGNPPLSSSKTITLHIL 443

Query: 446 DVNDNAPRFNQQLYTAYILENRPPGSLLCTVAASDPDTGDNARLTYSIVGNQVQGAPASS 505
           DVNDN P F+Q  YT ++ EN PPG+ +  V ASDPD G N  ++Y IV + ++    SS
Sbjct: 444 DVNDNVPVFHQASYTVHVAENNPPGASIAHVRASDPDLGPNGLVSYYIVASDLEPRELSS 503

Query: 506 FVYVNPEDGRIFAQRTFDYELLQMLQIVVGVRDSGSPPLHANTSLHVFVLDENDNAPAVL 565
           +V V+   G +FAQR FD+E L+  ++ +  RD GSP L AN SL V V D NDNAP VL
Sbjct: 504 YVSVSARSGVVFAQRAFDHEQLRAFELTLQARDQGSPTLSANVSLRVLVDDRNDNAPLVL 563

Query: 566 HPRPDWEHSAP-QRLPRSAPPGSLVTKVTAVDADAGHNAWLSYSLLPQSTAPGLFLVSTH 624
           +P    E SA    +PRSA PG LVTKV AVDAD+G+NAWLSY ++ Q++ PGLF +   
Sbjct: 564 YPALGPEGSALFDMVPRSAEPGYLVTKVVAVDADSGYNAWLSYHIV-QASEPGLFSLGLR 622

Query: 625 TGEVRTARALLEDDSDTQQVVVLVRDNGDPSLSSTATVLLVLEDEDPEEMPKSSDFLIHP 684
           TGEVRTAR L + ++  Q+++V VRD G   LS+T  + L+  D   E  P  SD     
Sbjct: 623 TGEVRTARTLGDREAARQRLLVTVRDGGQQPLSATVMLHLIFADSLQEIQPDLSDRPTPS 682

Query: 685 PERSDLTLYLIVALATVSLLSLVTFTFLSAKCLQGNADGDGGGGQCCRRQDSPSPDFYKQ 744
             +++L  +L+VALA +S+L L+      +  L+           C  R   P+ + Y Q
Sbjct: 683 DPQAELQFHLVVALALISVLFLLAVILAISLRLR-----------CSSR---PATEGYFQ 728

Query: 745 SSPNLQVSSDGTLKYMEVTLRPTDSQSHCYRTCFSPASDGSDFTFLRPLSVQQPTALALE 804
                +        Y E TL       + Y  C +  S  ++F FL   +        L 
Sbjct: 729 PGVCFKTVPGVLPTYSERTL------PYSYNPCAASHSSNTEFKFLNIKAENAAPQDLLC 782

Query: 805 PDAIRSRSNTLRER-------SQQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQFDT 857
            +A    SN   E         +QAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQFDT
Sbjct: 783 DEASWFESNDNPEMPSNSGNLQKQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQFDT 842

Query: 858 EMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATLT 917
           EMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATLT
Sbjct: 843 EMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATLT 902

Query: 918 NAAGKRDGKAPAGGNGNKKKSGKKEKK 944
           NAAGKRDGKAPAGGNGNKKKSGKKEKK
Sbjct: 903 NAAGKRDGKAPAGGNGNKKKSGKKEKK 929


>gi|9256600 protocadherin alpha subfamily C, 2 isoform 1 precursor
           [Homo sapiens]
          Length = 1007

 Score =  689 bits (1777), Expect = 0.0
 Identities = 396/967 (40%), Positives = 576/967 (59%), Gaps = 46/967 (4%)

Query: 15  VLCMLSLCCWGWVSGQLRYSVVEESEPGTLVGNVAQDLGLKMTDLLSRRLQLG--SEENG 72
           +L +L L   G  + QLRYSV EE  PG LVGNVA+ LGL++  L    L++      + 
Sbjct: 28  LLLLLLLLLPGPAASQLRYSVPEEQAPGALVGNVARALGLELRRLGPGCLRINHLGAPSP 87

Query: 73  RYFSLSLMSGALAVNQKIDRESLCGASTSCLLPVQVVTEHPLELIRVEVEILDLNDNSPS 132
           RY  L L SGAL VN++IDRE+LC     CLL ++V+  +P+ +  VEVEILD+NDNSP 
Sbjct: 88  RYLELDLTSGALFVNERIDREALCEQRPRCLLSLEVLAHNPVAVSAVEVEILDINDNSPR 147

Query: 133 FATPEREMRISESAASGARFPLDSAQDPDVGTNTVSFYTLSPNSHFSLNVKTLKDGKPFP 192
           F  P  ++++SES A GARF ++SAQDPDVG N+V  Y LSP+ HF L++K L++     
Sbjct: 148 FPRPNYQLQVSESVAPGARFHIESAQDPDVGANSVQTYELSPSEHFELDLKPLQENSKVL 207

Query: 193 ELVLEQQLDREAQARHQLVLTAVDGGTPARSGTTLISVIVLDINDNAPTFQSSVLRVGIP 252
           ELVL + LDRE  A H LVLTAVDGG PARSGT  ISV VLD NDN+P F  S  RV + 
Sbjct: 208 ELVLRKGLDREQAALHHLVLTAVDGGIPARSGTAQISVRVLDTNDNSPAFDQSTYRVQLR 267

Query: 253 ENAPIGTLLLRLNATDPDEGTNGQLDYSFGDHTSEAVRNLFGLDPSSGAIHVLGPIDFEE 312
           E++P GTL+++LNA+DPDEG+NG+L YS   +TS+  R LF +D S+G + V+G +D+EE
Sbjct: 268 EDSPPGTLVVKLNASDPDEGSNGELRYSLSSYTSDRERQLFSIDASTGEVRVIGGLDYEE 327

Query: 313 SRFYEIHARARDQGQPAMEGHCVIQVDVGDVNDNAPEVLLASLANPVLESTPVGTVVGLF 372
           +  Y+I+ +A D+G   M GHC + VD+ DVNDNAPEV+L  L +PV E+    T+V + 
Sbjct: 328 ASSYQIYVQATDRGPVPMAGHCKVLVDIVDVNDNAPEVVLTDLYSPVPENATPNTIVAVL 387

Query: 373 NVRDRDSGRNGEVSLDISPDLPFQIKPSENHYSLLTSQPLDREATSHYIIELLASDAGSP 432
           +V D+DSG N +VSL +   LPF++    N Y+L+ S PLDRE  + Y I + A+D G P
Sbjct: 388 SVNDQDSGPNRKVSLGLEATLPFRLNGFGNSYTLVVSGPLDRERVAVYNITVTATDGGIP 447

Query: 433 SLHKHLTIRLNISDVNDNAPRFNQQLYTAYILENRPPGSLLCTVAASDPDTGDNARLTYS 492
            L    T+++ ISD+NDN P F +  Y+ YI EN  PG LLCTV A+DPD  +NA +TYS
Sbjct: 448 QLTSLRTLKVEISDINDNPPSFLEDSYSIYIQENNLPGVLLCTVQATDPDEKENAEVTYS 507

Query: 493 IVGNQVQGAPASSFVYVNPEDGRIFAQRTFDYELLQMLQIVVGVRDSGSPPLHANTSLHV 552
           ++  ++QG P +S+V +N   G ++A  +FDYE  +   + V  +D GSPPL +  + +V
Sbjct: 508 LLEREIQGLPVTSYVSINSASGSLYAVNSFDYEKFREFFVTVEAQDKGSPPLSSTVTANV 567

Query: 553 FVLDENDNAPAVLHPRPDWEHSAPQRLPRSAPPGSLVTKVTAVDADAGHNAWLSYSLLPQ 612
           +V+D ND+AP +L+P      +A + +PR+AP G LVTKV A+D+D+G NAWL Y  L Q
Sbjct: 568 YVVDMNDHAPHILYPTSTNSSAAFEMVPRTAPAGYLVTKVIAMDSDSGQNAWLFYH-LAQ 626

Query: 613 STAPGLFLVSTHTGEVRTARALLEDDSDTQQVVVLVRDNGDPSLSSTATVLLVLEDEDPE 672
           ++   LF V  HTGE+RT R + ++   T  + V+VRDNG+PSLS++  + + + D   +
Sbjct: 627 TSDLDLFKVELHTGEIRTTRKMGDESGSTFNLTVVVRDNGEPSLSASVAITVAVVDRVSK 686

Query: 673 EMPKSSDFLIHPPERSDLTLYLIVALATVSLLSLVTFTFLS-AKCLQGNADGDG-GGGQC 730
            +P +   +  P   S++TLYLI+AL+TVS + L+T   LS  KC +  A G    GG C
Sbjct: 687 ILPDTQRHVKSPRTYSEITLYLIIALSTVSFIFLLTIIILSIIKCYRYTAYGTACCGGFC 746

Query: 731 CRRQDSPSPDFYKQSSPNLQVSSDGTLK----YMEVTLRPTDSQSHCYRTCFSPASDGSD 786
             R+ SP+ + YKQ++ N+       LK    ++EV    + ++++CY+ C +  S    
Sbjct: 747 GVRERSPA-ELYKQANNNIDARIPHGLKVQPHFIEVRGNGSLTKTYCYKACLTAGSGSDT 805

Query: 787 FTFLRPLSVQQPTALALEPDAIRSRS----------------NTLRERSQQAPPNTDWRF 830
           F F    +   P     +     SR+                N    +++   PN DWR+
Sbjct: 806 FMFYNTGAQTGPGPSGAQAAVTDSRNLTGQSGQNAGNLIILKNEAVSQNEPRQPNPDWRY 865

Query: 831 SQAQRPGTSGSQNGDDTGT------WPNNQFDTEMLQAMILASAS---EAADGSSTLGGG 881
           S + R G   S + ++ G        P+ Q+ T       ++SA+   EA + S  +G G
Sbjct: 866 SASLRAGMHSSVHLEEAGILRAGPGGPDQQWPT-------VSSATPEPEAGEVSPPVGAG 918

Query: 882 AGTMGLSARYGPQFTLQHVP-DYRQNVYIPGSNATLT---NAAGKRDGKAPAGGNGNKKK 937
             +   + +YGP    Q  P +      IPGS A ++        +  K+     G K++
Sbjct: 919 VNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKKEE 978

Query: 938 SGKKEKK 944
           + KK+KK
Sbjct: 979 TKKKKKK 985


>gi|14277682 protocadherin gamma subfamily C, 4 isoform 2 precursor
           [Homo sapiens]
          Length = 871

 Score =  678 bits (1750), Expect = 0.0
 Identities = 365/746 (48%), Positives = 492/746 (65%), Gaps = 13/746 (1%)

Query: 25  GWVSGQLRYSVVEESEPGTLVGNVAQDLGLKMTDLLSRRLQLGSEENGRYFSLSLMSGAL 84
           G+V GQ+RY V EES+ GT VGNVAQD  L    L +RRLQ+  E N R+F + L SGAL
Sbjct: 25  GYVCGQIRYPVPEESQEGTFVGNVAQDFLLDTDSLSARRLQVAGEVNQRHFRVDLDSGAL 84

Query: 85  AVNQKIDRESLCGASTSCLLPVQVVTEHPLELIRVEVEILDLNDNSPSFATPEREMRISE 144
            +   IDRE+LCG S SC++P++ VTE PLE+ R EVEI+D+ND++P F   + ++ I E
Sbjct: 85  LIKNPIDREALCGLSASCIVPLEFVTEGPLEMYRAEVEIVDVNDHAPRFPRQQLDLEIGE 144

Query: 145 SAASGARFPLDSAQDPDVGTNTVSFYTLSPNSHFSLNVKTLKDGKPFPELVLEQQLDREA 204
           +A  G RFPL+ AQD DVG+N++S Y LS N HF+L+VK   DG   PEL+LE+ LDRE 
Sbjct: 145 AAPPGQRFPLEKAQDADVGSNSISSYRLSSNEHFALDVKKRSDGSLVPELLLEKPLDREK 204

Query: 205 QARHQLVLTAVDGGTPARSGTTLISVIVLDINDNAPTFQSSVLRVGIPENAPIGTLLLRL 264
           Q+ ++LVLTAVDGG P RSGT  + V VLD+NDNAP FQ S  R+ + E+AP G +L++L
Sbjct: 205 QSDYRLVLTAVDGGNPPRSGTAELRVSVLDVNDNAPAFQQSSYRISVLESAPAGMVLIQL 264

Query: 265 NATDPDEGTNGQLDYSFGDHTSEAVRNLFGLDPSSGAIHVLGPIDFEESRFYEIHARARD 324
           NA+DPD G +G + + F  HT + VRNLF L P++G + +LGP+DFE   +YE   RARD
Sbjct: 265 NASDPDLGPSGNVTFYFSGHTPDRVRNLFSLHPTTGKLTLLGPLDFESENYYEFDVRARD 324

Query: 325 QGQPAMEGHCVIQVDVGDVNDNAPEVLLASLANPVLESTPVGTVVGLFNVRDRDSGRNGE 384
            G PAME HC ++VD+ DVNDNAP + + S    + ES   GTVV L +V+D DSG NG+
Sbjct: 325 GGSPAMEQHCSLRVDLLDVNDNAPYITVTSELGTLPESAEPGTVVALISVQDPDSGSNGD 384

Query: 385 VSLDISPDLPFQIKPS-ENHYSLLTSQPLDREATSHYIIELLASDAGSPSLHKHLTIRLN 443
           VSL I   LPF +K +  N +SL+T+ PLDREA S Y I + ASDAG+P L  H TI LN
Sbjct: 385 VSLRIPDHLPFALKSAFRNQFSLVTAGPLDREAKSSYDIMVTASDAGNPPLSTHRTIFLN 444

Query: 444 ISDVNDNAPRFNQQLYTAYILENRPPGSLLCTVAASDPDTGDNARLTYSIVGNQVQGAPA 503
           ISDVNDN P F Q+ +  ++ EN  PG LLC++AASDPD+G NA ++YS++  + +   A
Sbjct: 445 ISDVNDNPPSFFQRSHEVFVPENNRPGDLLCSLAASDPDSGLNALISYSLLEPRNRDVSA 504

Query: 504 SSFVYVNPEDGRIFAQRTFDYELLQMLQIVVGVRDSGSPPLHANTSLHVFVLDENDNAPA 563
           SSF+ +NP+ G + A R+FDYE  Q LQ  V  RD G+PPL +  ++ +FVLD NDNAPA
Sbjct: 505 SSFISLNPQTGAVHATRSFDYEQTQTLQFEVQARDRGNPPLSSTVTVRLFVLDLNDNAPA 564

Query: 564 VLHPRPDWEHSAPQRLPRSAPPGSLVTKVTAVDADAGHNAWLSYSLLPQSTAPGLFLVST 623
           VL PR       PQ LP S   G L+TKVTAVD D+G+NAW+SY LL ++  P LF VS 
Sbjct: 565 VLRPRARPGSLCPQALPPSVGAGHLITKVTAVDLDSGYNAWVSYQLL-EAPDPSLFAVSR 623

Query: 624 HTGEVRTARALLEDDSDTQQVVVLVRDNGDPSLSSTATVLLVLEDEDPEEMPKSSDFLIH 683
           + GEVRTA   +  D   Q++V++V+D+G P LS++ T+L+ LE++    +P   +    
Sbjct: 624 YAGEVRTA-VPIPADLPPQKLVIVVKDSGSPPLSTSVTLLVSLEEDTHPVVPDLRESSAP 682

Query: 684 PPERSDLTLYLIVALATVSLLSLVTFTFLSAKCLQGNADG----DGGGGQC---CRRQDS 736
               S LTLYL V+L  +  +S  +F  L +KCL+G A G      G   C    RR++ 
Sbjct: 683 REGESRLTLYLAVSLVAICFVSFGSFVALLSKCLRGAACGVTCFPAGTCACLTRSRRREG 742

Query: 737 PSPDFYKQSSPNLQVSSDGTLKYMEV 762
             P         +Q+ SD  +K+++V
Sbjct: 743 LPP---SNGILRIQLGSDDPIKFVDV 765


>gi|14165431 protocadherin alpha subfamily C, 2 isoform 2 precursor
           [Homo sapiens]
          Length = 884

 Score =  664 bits (1712), Expect = 0.0
 Identities = 355/783 (45%), Positives = 505/783 (64%), Gaps = 10/783 (1%)

Query: 15  VLCMLSLCCWGWVSGQLRYSVVEESEPGTLVGNVAQDLGLKMTDLLSRRLQLG--SEENG 72
           +L +L L   G  + QLRYSV EE  PG LVGNVA+ LGL++  L    L++      + 
Sbjct: 28  LLLLLLLLLPGPAASQLRYSVPEEQAPGALVGNVARALGLELRRLGPGCLRINHLGAPSP 87

Query: 73  RYFSLSLMSGALAVNQKIDRESLCGASTSCLLPVQVVTEHPLELIRVEVEILDLNDNSPS 132
           RY  L L SGAL VN++IDRE+LC     CLL ++V+  +P+ +  VEVEILD+NDNSP 
Sbjct: 88  RYLELDLTSGALFVNERIDREALCEQRPRCLLSLEVLAHNPVAVSAVEVEILDINDNSPR 147

Query: 133 FATPEREMRISESAASGARFPLDSAQDPDVGTNTVSFYTLSPNSHFSLNVKTLKDGKPFP 192
           F  P  ++++SES A GARF ++SAQDPDVG N+V  Y LSP+ HF L++K L++     
Sbjct: 148 FPRPNYQLQVSESVAPGARFHIESAQDPDVGANSVQTYELSPSEHFELDLKPLQENSKVL 207

Query: 193 ELVLEQQLDREAQARHQLVLTAVDGGTPARSGTTLISVIVLDINDNAPTFQSSVLRVGIP 252
           ELVL + LDRE  A H LVLTAVDGG PARSGT  ISV VLD NDN+P F  S  RV + 
Sbjct: 208 ELVLRKGLDREQAALHHLVLTAVDGGIPARSGTAQISVRVLDTNDNSPAFDQSTYRVQLR 267

Query: 253 ENAPIGTLLLRLNATDPDEGTNGQLDYSFGDHTSEAVRNLFGLDPSSGAIHVLGPIDFEE 312
           E++P GTL+++LNA+DPDEG+NG+L YS   +TS+  R LF +D S+G + V+G +D+EE
Sbjct: 268 EDSPPGTLVVKLNASDPDEGSNGELRYSLSSYTSDRERQLFSIDASTGEVRVIGGLDYEE 327

Query: 313 SRFYEIHARARDQGQPAMEGHCVIQVDVGDVNDNAPEVLLASLANPVLESTPVGTVVGLF 372
           +  Y+I+ +A D+G   M GHC + VD+ DVNDNAPEV+L  L +PV E+    T+V + 
Sbjct: 328 ASSYQIYVQATDRGPVPMAGHCKVLVDIVDVNDNAPEVVLTDLYSPVPENATPNTIVAVL 387

Query: 373 NVRDRDSGRNGEVSLDISPDLPFQIKPSENHYSLLTSQPLDREATSHYIIELLASDAGSP 432
           +V D+DSG N +VSL +   LPF++    N Y+L+ S PLDRE  + Y I + A+D G P
Sbjct: 388 SVNDQDSGPNRKVSLGLEATLPFRLNGFGNSYTLVVSGPLDRERVAVYNITVTATDGGIP 447

Query: 433 SLHKHLTIRLNISDVNDNAPRFNQQLYTAYILENRPPGSLLCTVAASDPDTGDNARLTYS 492
            L    T+++ ISD+NDN P F +  Y+ YI EN  PG LLCTV A+DPD  +NA +TYS
Sbjct: 448 QLTSLRTLKVEISDINDNPPSFLEDSYSIYIQENNLPGVLLCTVQATDPDEKENAEVTYS 507

Query: 493 IVGNQVQGAPASSFVYVNPEDGRIFAQRTFDYELLQMLQIVVGVRDSGSPPLHANTSLHV 552
           ++  ++QG P +S+V +N   G ++A  +FDYE  +   + V  +D GSPPL +  + +V
Sbjct: 508 LLEREIQGLPVTSYVSINSASGSLYAVNSFDYEKFREFFVTVEAQDKGSPPLSSTVTANV 567

Query: 553 FVLDENDNAPAVLHPRPDWEHSAPQRLPRSAPPGSLVTKVTAVDADAGHNAWLSYSLLPQ 612
           +V+D ND+AP +L+P      +A + +PR+AP G LVTKV A+D+D+G NAWL Y  L Q
Sbjct: 568 YVVDMNDHAPHILYPTSTNSSAAFEMVPRTAPAGYLVTKVIAMDSDSGQNAWLFYH-LAQ 626

Query: 613 STAPGLFLVSTHTGEVRTARALLEDDSDTQQVVVLVRDNGDPSLSSTATVLLVLEDEDPE 672
           ++   LF V  HTGE+RT R + ++   T  + V+VRDNG+PSLS++  + + + D   +
Sbjct: 627 TSDLDLFKVELHTGEIRTTRKMGDESGSTFNLTVVVRDNGEPSLSASVAITVAVVDRVSK 686

Query: 673 EMPKSSDFLIHPPERSDLTLYLIVALATVSLLSLVTFTFLS-AKCLQGNADGDG-GGGQC 730
            +P +   +  P   S++TLYLI+AL+TVS + L+T   LS  KC +  A G    GG C
Sbjct: 687 ILPDTQRHVKSPRTYSEITLYLIIALSTVSFIFLLTIIILSIIKCYRYTAYGTACCGGFC 746

Query: 731 CRRQDSPSPDFYKQSSPNLQVSSDGTLK----YMEVTLRPTDSQSHCYRTCFSPASDGSD 786
             R+ SP+ + YKQ++ N+       LK    ++EV    + ++++CY+ C +  S    
Sbjct: 747 GVRERSPA-ELYKQANNNIDARIPHGLKVQPHFIEVRGNGSLTKTYCYKACLTAGSGSDT 805

Query: 787 FTF 789
           F F
Sbjct: 806 FMF 808


>gi|14589916 protocadherin 10 isoform 1 precursor [Homo sapiens]
          Length = 1040

 Score =  635 bits (1638), Expect = 0.0
 Identities = 385/970 (39%), Positives = 546/970 (56%), Gaps = 87/970 (8%)

Query: 27  VSGQLRYSVVEESEPGTLVGNVAQDLGLKMTDLLSRRLQLGSEENGRYFSLSLMSGALAV 86
           V  QL Y+V EE E GT VGN+A+DLGL +T L +R  Q        Y  L+L +G L V
Sbjct: 16  VFSQLHYTVQEEQEHGTFVGNIAEDLGLDITKLSARGFQTVPNSRTPYLDLNLETGVLYV 75

Query: 87  NQKIDRESLCGASTSCLLPVQVVTEHPLELIRVEVEILDLNDNSPSFATPEREMRISESA 146
           N+KIDRE +C  S SC+L ++V  E+PLEL +VE+E+LD+NDN PSF  P+  + ISESA
Sbjct: 76  NEKIDREQICKQSPSCVLHLEVFLENPLELFQVEIEVLDINDNPPSFPEPDLTVEISESA 135

Query: 147 ASGARFPLDSAQDPDVGTNTVSFYTLSPNSHFSLNVKTLKDGKPFPELVLEQQLDREAQA 206
             G RFPL+SA DPDVGTN++  Y ++PNS+FSL+V+T  DG  F ELVLE+ LDRE QA
Sbjct: 136 TPGTRFPLESAFDPDVGTNSLRDYEITPNSYFSLDVQTQGDGNRFAELVLEKPLDREQQA 195

Query: 207 RHQLVLTAVDGG-------------------TPARSGTTLISVIVLDINDNAPTFQSSVL 247
            H+ VLTAVDGG                      R+GT L+++ VLD NDN P F   V 
Sbjct: 196 VHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLTIRVLDSNDNVPAFDQPVY 255

Query: 248 RVGIPENAPIGTLLLRLNATDPDEGTNGQLDYSFGDHTSEAVRNLFGLDPSSGAIHVLGP 307
            V +PEN+P GTL+++LNATDPDEG NG++ YSF  H S   R LFGL P +G + V G 
Sbjct: 256 TVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRARELFGLSPRTGRLEVSGE 315

Query: 308 IDFEESRFYEIHARARDQGQPAMEGHCVIQVDVGDVNDNAPEVLLASLANPVLESTPVGT 367
           +D+EES  Y+++ +A+D G  A+  HC + V V D NDNAPE+  +++   V E    GT
Sbjct: 316 LDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPEISFSTVKEAVSEGAAPGT 375

Query: 368 VVGLFNVRDRDSGRNGEVSLDISPDLPFQIKPS-ENHYSLLTSQPLDREATSHYIIELLA 426
           VV LF+V DRDS  NG+V  ++  D+PF++K S +N+Y+++T  PLDREA   Y + ++A
Sbjct: 376 VVALFSVTDRDSEENGQVQCELLGDVPFRLKSSFKNYYTIVTEAPLDREAGDSYTLTVVA 435

Query: 427 SDAGSPSLHKHLTIRLNISDVNDNAPRFNQQLYTAYILENRPPGSLLCTVAASDPDTGDN 486
            D G P+L    +I++ +SDVNDNAPRF+Q +Y  Y+ EN  PG+ +  V+A+D D G N
Sbjct: 436 RDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNVPGAYIYAVSATDRDEGAN 495

Query: 487 ARLTYSIVGNQVQGAPASSFVYVNPEDGRIFAQRTFDYELLQMLQIVVGVRDSGSP-PLH 545
           A+L YSI+  Q+QG    ++V +N E+G ++A R+FDYE L+     V  RD+GSP  L 
Sbjct: 496 AQLAYSILECQIQGMSVFTYVSINSENGYLYALRSFDYEQLKDFSFQVEARDAGSPQALA 555

Query: 546 ANTSLHVFVLDENDNAPAVLHPRPDWEHSAPQR--LPRSAPPGSLVTKVTAVDADAGHNA 603
            N ++++ ++D+NDNAPA++ P P   +  P R  LPRSA PG L+T+V AVDAD G NA
Sbjct: 556 GNATVNILIVDQNDNAPAIVAPLPG-RNGTPAREVLPRSAEPGYLLTRVAAVDADDGENA 614

Query: 604 WLSYSLLPQSTAPGLFLVSTHTGEVRTARAL--LEDDSDTQQVVVLVRDNGDPSLSSTAT 661
            L+YS++ +     LF +   TGE+RTAR +    D     ++V+ VRD+G P LSSTAT
Sbjct: 615 RLTYSIV-RGNEMNLFRMDWRTGELRTARRVPAKRDPQRPYELVIEVRDHGQPPLSSTAT 673

Query: 662 VLLVLEDEDPEEM-----PKSSDFLIHPPERS-------DLTLYLIVALATVSLLSLVTF 709
           +++ L D   E                 P RS       DLTL LI+AL +VS + L+  
Sbjct: 674 LVVQLVDGAVEPQGGGGSGGGGSGEHQRPSRSGGGETSLDLTLILIIALGSVSFIFLLAM 733

Query: 710 TFLSAKCLQGNADG----------------DGGGGQCCRRQDSPSPDFYKQSSPNLQVSS 753
             L+ +C +                      GGG  CC RQ         +S   L  SS
Sbjct: 734 IVLAVRCQKEKKLNIYTCLASDCCLCCCCCGGGGSTCCGRQARARKKKLSKSDIMLVQSS 793

Query: 754 DGTLKYMEVTLRPT-------DSQSHCYRTCFSPASDGSDFTFLRPLSVQQPTALA---- 802
           +      +V +  +        +Q++CY+ C +P S  +D  FL+P S  + T       
Sbjct: 794 NVPSNPAQVPIEESGGFGSHHHNQNYCYQVCLTPESAKTDLMFLKPCSPSRSTDTEHNPC 853

Query: 803 ---------LEPDAIRSRSNTLRERSQQAPPNTDWRFSQAQRPGTSGSQNGD-----DTG 848
                     +PD I S  + L   ++       +   + +R  +S  Q  D     D+G
Sbjct: 854 GAIVTGYTDQQPDII-SNGSILSNETKHQRAELSYLVDRPRRVNSSAFQEADIVSSKDSG 912

Query: 849 TWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSAR-YGPQFTL---QHVPDYR 904
              + Q D++        + S   D  S        +G S R + P F     +   DYR
Sbjct: 913 HGDSEQGDSD--HDATNRAQSAGMDLFSNCTEECKALGHSDRCWMPSFVPSDGRQAADYR 970

Query: 905 QNVYIPGSNA 914
            N+++PG ++
Sbjct: 971 SNLHVPGMDS 980


>gi|14589914 protocadherin 10 isoform 2 precursor [Homo sapiens]
          Length = 896

 Score =  629 bits (1622), Expect = e-180
 Identities = 358/833 (42%), Positives = 498/833 (59%), Gaps = 62/833 (7%)

Query: 27  VSGQLRYSVVEESEPGTLVGNVAQDLGLKMTDLLSRRLQLGSEENGRYFSLSLMSGALAV 86
           V  QL Y+V EE E GT VGN+A+DLGL +T L +R  Q        Y  L+L +G L V
Sbjct: 16  VFSQLHYTVQEEQEHGTFVGNIAEDLGLDITKLSARGFQTVPNSRTPYLDLNLETGVLYV 75

Query: 87  NQKIDRESLCGASTSCLLPVQVVTEHPLELIRVEVEILDLNDNSPSFATPEREMRISESA 146
           N+KIDRE +C  S SC+L ++V  E+PLEL +VE+E+LD+NDN PSF  P+  + ISESA
Sbjct: 76  NEKIDREQICKQSPSCVLHLEVFLENPLELFQVEIEVLDINDNPPSFPEPDLTVEISESA 135

Query: 147 ASGARFPLDSAQDPDVGTNTVSFYTLSPNSHFSLNVKTLKDGKPFPELVLEQQLDREAQA 206
             G RFPL+SA DPDVGTN++  Y ++PNS+FSL+V+T  DG  F ELVLE+ LDRE QA
Sbjct: 136 TPGTRFPLESAFDPDVGTNSLRDYEITPNSYFSLDVQTQGDGNRFAELVLEKPLDREQQA 195

Query: 207 RHQLVLTAVDGG-------------------TPARSGTTLISVIVLDINDNAPTFQSSVL 247
            H+ VLTAVDGG                      R+GT L+++ VLD NDN P F   V 
Sbjct: 196 VHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLTIRVLDSNDNVPAFDQPVY 255

Query: 248 RVGIPENAPIGTLLLRLNATDPDEGTNGQLDYSFGDHTSEAVRNLFGLDPSSGAIHVLGP 307
            V +PEN+P GTL+++LNATDPDEG NG++ YSF  H S   R LFGL P +G + V G 
Sbjct: 256 TVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRARELFGLSPRTGRLEVSGE 315

Query: 308 IDFEESRFYEIHARARDQGQPAMEGHCVIQVDVGDVNDNAPEVLLASLANPVLESTPVGT 367
           +D+EES  Y+++ +A+D G  A+  HC + V V D NDNAPE+  +++   V E    GT
Sbjct: 316 LDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPEISFSTVKEAVSEGAAPGT 375

Query: 368 VVGLFNVRDRDSGRNGEVSLDISPDLPFQIKPS-ENHYSLLTSQPLDREATSHYIIELLA 426
           VV LF+V DRDS  NG+V  ++  D+PF++K S +N+Y+++T  PLDREA   Y + ++A
Sbjct: 376 VVALFSVTDRDSEENGQVQCELLGDVPFRLKSSFKNYYTIVTEAPLDREAGDSYTLTVVA 435

Query: 427 SDAGSPSLHKHLTIRLNISDVNDNAPRFNQQLYTAYILENRPPGSLLCTVAASDPDTGDN 486
            D G P+L    +I++ +SDVNDNAPRF+Q +Y  Y+ EN  PG+ +  V+A+D D G N
Sbjct: 436 RDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNVPGAYIYAVSATDRDEGAN 495

Query: 487 ARLTYSIVGNQVQGAPASSFVYVNPEDGRIFAQRTFDYELLQMLQIVVGVRDSGSP-PLH 545
           A+L YSI+  Q+QG    ++V +N E+G ++A R+FDYE L+     V  RD+GSP  L 
Sbjct: 496 AQLAYSILECQIQGMSVFTYVSINSENGYLYALRSFDYEQLKDFSFQVEARDAGSPQALA 555

Query: 546 ANTSLHVFVLDENDNAPAVLHPRPDWEHSAPQR--LPRSAPPGSLVTKVTAVDADAGHNA 603
            N ++++ ++D+NDNAPA++ P P   +  P R  LPRSA PG L+T+V AVDAD G NA
Sbjct: 556 GNATVNILIVDQNDNAPAIVAPLPG-RNGTPAREVLPRSAEPGYLLTRVAAVDADDGENA 614

Query: 604 WLSYSLLPQSTAPGLFLVSTHTGEVRTARAL--LEDDSDTQQVVVLVRDNGDPSLSSTAT 661
            L+YS++ +     LF +   TGE+RTAR +    D     ++V+ VRD+G P LSSTAT
Sbjct: 615 RLTYSIV-RGNEMNLFRMDWRTGELRTARRVPAKRDPQRPYELVIEVRDHGQPPLSSTAT 673

Query: 662 VLLVLEDEDPEEM-----PKSSDFLIHPPERS-------DLTLYLIVALATVSLLSLVTF 709
           +++ L D   E                 P RS       DLTL LI+AL +VS + L+  
Sbjct: 674 LVVQLVDGAVEPQGGGGSGGGGSGEHQRPSRSGGGETSLDLTLILIIALGSVSFIFLLAM 733

Query: 710 TFLSAKCLQGNADG----------------DGGGGQCCRRQDSPSPDFYKQSSPNLQVSS 753
             L+ +C +                      GGG  CC RQ         +S   L  SS
Sbjct: 734 IVLAVRCQKEKKLNIYTCLASDCCLCCCCCGGGGSTCCGRQARARKKKLSKSDIMLVQSS 793

Query: 754 DGTLKYMEVTLRPT-------DSQSHCYRTCFSPASDGSDFTFLRPLSVQQPT 799
           +      +V +  +        +Q++CY+ C +P S  +D  FL+P S  + T
Sbjct: 794 NVPSNPAQVPIEESGGFGSHHHNQNYCYQVCLTPESAKTDLMFLKPCSPSRST 846


>gi|9256586 protocadherin alpha 3 isoform 1 precursor [Homo sapiens]
          Length = 950

 Score =  621 bits (1601), Expect = e-177
 Identities = 373/951 (39%), Positives = 551/951 (57%), Gaps = 58/951 (6%)

Query: 15  VLCMLSLCCWGWVSGQLRYSVVEESEPGTLVGNVAQDLGLKMTDLLSRRLQLGSEENGRY 74
           +L +L L      SGQL YSV EE++ GT VG +AQDLGL++ +L+ R  ++ S+ +G  
Sbjct: 15  LLSLLLLAASEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKRHGDL 74

Query: 75  FSLSLMSGALAVNQKIDRESLCGASTSCLLPVQVVTEHPLELIRVEVEILDLNDNSPSFA 134
             ++L +G L VN +IDRE LCG S  C + ++V+ + PL++  VEVE+ D+NDN+P F 
Sbjct: 75  LEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVEVKDINDNAPVFP 134

Query: 135 TPEREMRISESAASGARFPLDSAQDPDVGTNTVSFYTLSPNSHFSLNVKTLKDGKPFPEL 194
              + + ISES   G+RF L+ A D D+GTN++  Y+L    +F+L+VK   +      L
Sbjct: 135 MAVKNLFISESRQPGSRFSLEGASDADIGTNSLLTYSLDSTEYFTLDVKRNDEEIKSLGL 194

Query: 195 VLEQQLDREAQARHQLVLTAVDGGTPARSGTTLISVIVLDINDNAPTFQSSVLRVGIPEN 254
           VL++ L+RE   +H L++TA+DGG P  +GTT + + VLD+NDNAP F+ ++ +V + EN
Sbjct: 195 VLKKNLNREDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAPAFERTIYKVRLLEN 254

Query: 255 APIGTLLLRLNATDPDEGTNGQLDYSFGDHTSEAVRNLFGLDPSSGAIHVLGPIDFEESR 314
           AP GTL++ +NATD DEG N  + YSF    S  + + F LDP +G I V G IDFEES+
Sbjct: 255 APNGTLVVTVNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNGQISVKGNIDFEESK 314

Query: 315 FYEIHARARDQGQPAMEGHCVIQVDVGDVNDNAPEVLLASLANPVLESTPVGTVVGLFNV 374
            YEI   A D+G P M  HC + +++ D+NDN PE+++ SL+ PVLE +P+ TV+ L +V
Sbjct: 315 SYEIQVEATDKGNPPMSDHCTVLLEIVDINDNVPELVIQSLSLPVLEDSPLSTVIALISV 374

Query: 375 RDRDSGRNGEVSLDISPDLPFQ-IKPSENHYSLLTSQPLDREATSHYIIELLASDAGSPS 433
            DRDSG NG+V+  ++P +PF+ +   +N+YSL+   PLDRE+ S Y + + A D GSPS
Sbjct: 375 SDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSPLDRESVSAYELVVTARDGGSPS 434

Query: 434 LHKHLTIRLNISDVNDNAPRFNQQLYTAYILENRPPGSLLCTVAASDPDTGDNARLTYSI 493
           L    ++ + ++DVNDNAP F+Q  YT ++ EN PPG  + TV+A D D  +NA ++YS+
Sbjct: 435 LWATASVSVEVADVNDNAPAFSQSEYTVFVKENNPPGCHIFTVSARDADAQENALVSYSL 494

Query: 494 VGNQVQGAPASSFVYVNPEDGRIFAQRTFDYELLQMLQIVVGVRDSGSPPLHANTSLHVF 553
           V  +V     SS+V V+ E G+++A +  D+E L++LQ  V  RD+G PPL +N +L VF
Sbjct: 495 VERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQVF 554

Query: 554 VLDENDNAPAVLHPRPDWEHSAPQRL-PRSAPPGSLVTKVTAVDADAGHNAWLSYSLLPQ 612
           VLDENDNAPA+L PR      A   L PRS   G +V KV AVDAD+G+NAWLSY L P 
Sbjct: 555 VLDENDNAPALLMPRVGGIGGAVSELVPRSVGAGHVVAKVRAVDADSGYNAWLSYELQPG 614

Query: 613 STAPGL-FLVSTHTGEVRTARALLEDDSDTQQVVVLVRDNGDPSLSSTATVL--LVLEDE 669
           +    + F V  +TGE+ T RAL E D+   +++VLV+D+G+PSL++TATVL  LV   +
Sbjct: 615 TGGARIPFRVGLYTGEISTTRALDEVDAPRHRLLVLVKDHGEPSLTATATVLVSLVESGQ 674

Query: 670 DPEEMPKSSDFLIHPPER-SDLTLYLIVALATV-SLLSLVTFTFLSAKCLQGNADGDGGG 727
            P+   ++S     P     D+ +YLIVA+  V SLL L    + + +C     +GD G 
Sbjct: 675 APKASSQASAGATGPEAALVDVNVYLIVAICAVSSLLVLTLLLYTALRCSAPPTEGDCGP 734

Query: 728 GQCCRRQDSPSPDFYKQSSPNLQVSSD-GTLKYMEVTLRPTDSQSHCYRTCFSPASDGSD 786
           G+                 P L  SS  G+  Y         SQ    R C   + +G  
Sbjct: 735 GK-----------------PTLVCSSAVGSWSY---------SQQRQQRVC---SGEGLP 765

Query: 787 FTFLRPLSVQQPTALALEPDAIRSRSNTLRERSQQAPPNTDWRFSQAQRPGTSGSQNGDD 846
            T L   S   P    +  D    +   +   ++   PN DWR+S + R G   S + ++
Sbjct: 766 KTDLMAFSPSLPPC-PISRDREEKQDVDVDLSAKPRQPNPDWRYSASLRAGMHSSVHLEE 824

Query: 847 TGT------WPNNQFDTEMLQAMILASAS---EAADGSSTLGGGAGTMGLSARYGPQFTL 897
            G        P+ Q+ T       ++SA+   EA + S  +G G  +   + +YGP    
Sbjct: 825 AGILRAGPGGPDQQWPT-------VSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPK 877

Query: 898 QHVP-DYRQNVYIPGSNATLT---NAAGKRDGKAPAGGNGNKKKSGKKEKK 944
           Q  P +      IPGS A ++        +  K+     G K+++ KK+KK
Sbjct: 878 QSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKKEETKKKKKK 928


>gi|9256596 protocadherin alpha 8 isoform 1 precursor [Homo sapiens]
          Length = 950

 Score =  614 bits (1584), Expect = e-175
 Identities = 376/955 (39%), Positives = 540/955 (56%), Gaps = 57/955 (5%)

Query: 11  GKWQVLCMLSL-CCWGWVSGQLRYSVVEESEPGTLVGNVAQDLGLKMTDLLSRRLQLGSE 69
           G W++L +L L   W   SGQL YSV EE++ GT VG +AQDLGL++ +L+ R  ++ S+
Sbjct: 10  GSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRVASK 69

Query: 70  ENGRYFSLSLMSGALAVNQKIDRESLCGASTSCLLPVQVVTEHPLELIRVEVEILDLNDN 129
            +     +SL +G L VN +IDRE LCG S  C + ++V+ + PL++  V+VE+ D+NDN
Sbjct: 70  RHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDVNDN 129

Query: 130 SPSFATPEREMRISESAASGARFPLDSAQDPDVGTNTVSFYTLSPNSHFSLNVKTLKDGK 189
            P F   ++++ +SES    +RFPL+ A D DVG N+V  Y LS + +F L+V +  D  
Sbjct: 130 PPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFMLDVNSKNDEN 189

Query: 190 PFPELVLEQQLDREAQARHQLVLTAVDGGTPARSGTTLISVIVLDINDNAPTFQSSVLRV 249
              ELVL + LDRE    H L LTA DGG P  +GT  + V VLD+NDNAPTF+ S   V
Sbjct: 190 KLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEV 249

Query: 250 GIPENAPIGTLLLRLNATDPDEGTNGQLDYSFGDHTSEAVRNLFGLDPSSGAIHVLGPID 309
            I ENA  GT +++LNA+DPDEG NG + YSF       V + F +D ++G I + G +D
Sbjct: 250 RIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTGEIVIRGNLD 309

Query: 310 FEESRFYEIHARARDQGQPAMEGHCVIQVDVGDVNDNAPEVLLASLANPVLESTPVGTVV 369
           FE+   Y+I   A D+G P M GHC + V + D NDN PE+ L SL+ PV E    GTV+
Sbjct: 310 FEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTVI 369

Query: 370 GLFNVRDRDSGRNGEVSLDISPDLPFQ-IKPSENHYSLLTSQPLDREATSHYIIELLASD 428
            L +V D DSG NG+V+  + P +PF+ +   +N+YSL+    LDRE  S Y + + A D
Sbjct: 370 ALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSAYELVVTARD 429

Query: 429 AGSPSLHKHLTIRLNISDVNDNAPRFNQQLYTAYILENRPPGSLLCTVAASDPDTGDNAR 488
            GSPSL    ++ + ++DVNDNAP F Q  YT ++ EN PPG  + TV+A D D  +NA 
Sbjct: 430 GGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENAL 489

Query: 489 LTYSIVGNQVQGAPASSFVYVNPEDGRIFAQRTFDYELLQMLQIVVGVRDSGSPPLHANT 548
           ++YS+V  +V     SS++ V+ E G+++A +  D+E L++LQ  V  RD+G PPL +N 
Sbjct: 490 VSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549

Query: 549 SLHVFVLDENDNAPAVLHPRPDWEHSAPQRL-PRSAPPGSLVTKVTAVDADAGHNAWLSY 607
           +L VFVLDENDNAPA+L PR      A  +L PRS   G +V KV AVDAD+G+NAWLSY
Sbjct: 550 TLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDADSGYNAWLSY 609

Query: 608 SLLPQSTAPGL-FLVSTHTGEVRTARALLEDDSDTQQVVVLVRDNGDPSLSSTATVL--L 664
            L P +++P + F V  +TGE+ T R L E DS   +++VLV+D+G+P+L++TATVL  L
Sbjct: 610 ELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVSL 669

Query: 665 VLEDEDPEEMPKSSDFLIHPPER-SDLTLYLIVALATVSLLSLVTFTFLSAKCLQGNADG 723
           V   + P+   + S  ++ P     D+ +YLI+A+  VS  SL+  T L    L+ +A  
Sbjct: 670 VESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVS--SLLVLTLLLYTALRCSALP 727

Query: 724 DGGGGQCCRRQDSPSPDFYKQSSPNLQVSSD-GTLKYMEVTLRPTDSQSHCYRTCFSPAS 782
             GG   CR              P L  SS  G+  Y         SQ    R C   + 
Sbjct: 728 TEGG---CR-----------AGKPTLVCSSAVGSWSY---------SQQQPQRVC---SG 761

Query: 783 DGSDFTFLRPLSVQQPTALALEPDAIRSRSNTLRERSQQAPPNTDWRFSQAQRPGTSGSQ 842
           +G   T L   S   P  L    D    +   +    +   PN DWR+S + R G   S 
Sbjct: 762 EGPPKTDLMAFSPCLPPDLG-SVDVGEEQDLNVDHGLKPRQPNPDWRYSASLRAGMHSSV 820

Query: 843 NGDDTGT------WPNNQFDTEMLQAMILASAS---EAADGSSTLGGGAGTMGLSARYGP 893
           + ++ G        P+ Q+ T       ++SA+   EA + S  +G G  +   + +YGP
Sbjct: 821 HLEEAGILRAGPGGPDQQWPT-------VSSATPEPEAGEVSPPVGAGVNSNSWTFKYGP 873

Query: 894 QFTLQHVP-DYRQNVYIPGSNATLT---NAAGKRDGKAPAGGNGNKKKSGKKEKK 944
               Q  P +      IPGS A ++        +  K+     G K+++ KK+KK
Sbjct: 874 GNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKKEETKKKKKK 928


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.132    0.385 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 39,464,917
Number of Sequences: 37866
Number of extensions: 1933111
Number of successful extensions: 10933
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 186
Number of HSP's successfully gapped in prelim test: 25
Number of HSP's that attempted gapping in prelim test: 3666
Number of HSP's gapped (non-prelim): 665
length of query: 944
length of database: 18,247,518
effective HSP length: 112
effective length of query: 832
effective length of database: 14,006,526
effective search space: 11653429632
effective search space used: 11653429632
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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