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Search of human proteins with 111038133
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|111038133 neuroguidin isoform 2 [Homo sapiens]
(311 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|111038133 neuroguidin isoform 2 [Homo sapiens] 602 e-172
gi|111038128 neuroguidin isoform 1 [Homo sapiens] 600 e-172
gi|9966799 UTP3, small subunit processome component [Homo sapiens] 61 1e-09
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 44 1e-04
gi|34878777 ring finger protein 20 [Homo sapiens] 42 5e-04
gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi... 42 0.001
gi|116256481 TNFAIP3 interacting protein 1 [Homo sapiens] 41 0.002
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 41 0.002
gi|148746195 trichohyalin [Homo sapiens] 40 0.002
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 40 0.003
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 40 0.003
gi|41054864 regulating synaptic membrane exocytosis 1 [Homo sapi... 39 0.005
gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapi... 38 0.010
gi|114155142 nuclear pore complex-associated protein TPR [Homo s... 38 0.010
gi|221219020 NYD-SP11 protein [Homo sapiens] 38 0.013
gi|239735592 TRAF2 and NCK interacting kinase isoform 8 [Homo sa... 38 0.013
gi|239735590 TRAF2 and NCK interacting kinase isoform 7 [Homo sa... 38 0.013
gi|239735588 TRAF2 and NCK interacting kinase isoform 6 [Homo sa... 38 0.013
gi|239735586 TRAF2 and NCK interacting kinase isoform 5 [Homo sa... 38 0.013
gi|239735584 TRAF2 and NCK interacting kinase isoform 4 [Homo sa... 38 0.013
gi|239735582 TRAF2 and NCK interacting kinase isoform 3 [Homo sa... 38 0.013
gi|239735580 TRAF2 and NCK interacting kinase isoform 2 [Homo sa... 38 0.013
gi|55741807 TRAF2 and NCK interacting kinase isoform 1 [Homo sap... 38 0.013
gi|218505787 protocadherin 15 isoform CD2-1 precursor [Homo sapi... 37 0.017
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 37 0.022
gi|56090620 NFKB activating protein-like [Homo sapiens] 37 0.022
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo... 37 0.029
gi|169166558 PREDICTED: similar to hCG18094 [Homo sapiens] 36 0.050
gi|169167297 PREDICTED: similar to hCG18094 [Homo sapiens] 36 0.050
gi|169166473 PREDICTED: similar to hCG18094 [Homo sapiens] 36 0.050
>gi|111038133 neuroguidin isoform 2 [Homo sapiens]
Length = 311
Score = 602 bits (1551), Expect = e-172
Identities = 311/311 (100%), Positives = 311/311 (100%)
Query: 1 MAALGVLESDLPSAVTLLKNLQEQVMAVTAQVKSLTQKVQAGAYPTEKGLSFLEVKDQLL 60
MAALGVLESDLPSAVTLLKNLQEQVMAVTAQVKSLTQKVQAGAYPTEKGLSFLEVKDQLL
Sbjct: 1 MAALGVLESDLPSAVTLLKNLQEQVMAVTAQVKSLTQKVQAGAYPTEKGLSFLEVKDQLL 60
Query: 61 LMYLMDLTHLILDKASGGSLQGHDAVLRLVEIRTVLEKLRPLDQKLKYQIDKLIKTAVTG 120
LMYLMDLTHLILDKASGGSLQGHDAVLRLVEIRTVLEKLRPLDQKLKYQIDKLIKTAVTG
Sbjct: 61 LMYLMDLTHLILDKASGGSLQGHDAVLRLVEIRTVLEKLRPLDQKLKYQIDKLIKTAVTG 120
Query: 121 SLSENDPLRFKPHPSNMMSKLSSEDEEEDEAEDDQSEASGKKSVKGVSKKYVPPRLVPVH 180
SLSENDPLRFKPHPSNMMSKLSSEDEEEDEAEDDQSEASGKKSVKGVSKKYVPPRLVPVH
Sbjct: 121 SLSENDPLRFKPHPSNMMSKLSSEDEEEDEAEDDQSEASGKKSVKGVSKKYVPPRLVPVH 180
Query: 181 YDETEAEREKKRLERAKRRALSSSVIRELKEQYSDAPEEIRDARHPHVTRQSQEDQHRIN 240
YDETEAEREKKRLERAKRRALSSSVIRELKEQYSDAPEEIRDARHPHVTRQSQEDQHRIN
Sbjct: 181 YDETEAEREKKRLERAKRRALSSSVIRELKEQYSDAPEEIRDARHPHVTRQSQEDQHRIN 240
Query: 241 YEESMMVRLSVSKREKGRRKRANVMSSQLHSLTHFSDISALTGGTVHLDEDQNPIKKRKK 300
YEESMMVRLSVSKREKGRRKRANVMSSQLHSLTHFSDISALTGGTVHLDEDQNPIKKRKK
Sbjct: 241 YEESMMVRLSVSKREKGRRKRANVMSSQLHSLTHFSDISALTGGTVHLDEDQNPIKKRKK 300
Query: 301 IPQKGRKKKGQ 311
IPQKGRKKKGQ
Sbjct: 301 IPQKGRKKKGQ 311
>gi|111038128 neuroguidin isoform 1 [Homo sapiens]
Length = 315
Score = 600 bits (1546), Expect = e-172
Identities = 310/310 (100%), Positives = 310/310 (100%)
Query: 1 MAALGVLESDLPSAVTLLKNLQEQVMAVTAQVKSLTQKVQAGAYPTEKGLSFLEVKDQLL 60
MAALGVLESDLPSAVTLLKNLQEQVMAVTAQVKSLTQKVQAGAYPTEKGLSFLEVKDQLL
Sbjct: 1 MAALGVLESDLPSAVTLLKNLQEQVMAVTAQVKSLTQKVQAGAYPTEKGLSFLEVKDQLL 60
Query: 61 LMYLMDLTHLILDKASGGSLQGHDAVLRLVEIRTVLEKLRPLDQKLKYQIDKLIKTAVTG 120
LMYLMDLTHLILDKASGGSLQGHDAVLRLVEIRTVLEKLRPLDQKLKYQIDKLIKTAVTG
Sbjct: 61 LMYLMDLTHLILDKASGGSLQGHDAVLRLVEIRTVLEKLRPLDQKLKYQIDKLIKTAVTG 120
Query: 121 SLSENDPLRFKPHPSNMMSKLSSEDEEEDEAEDDQSEASGKKSVKGVSKKYVPPRLVPVH 180
SLSENDPLRFKPHPSNMMSKLSSEDEEEDEAEDDQSEASGKKSVKGVSKKYVPPRLVPVH
Sbjct: 121 SLSENDPLRFKPHPSNMMSKLSSEDEEEDEAEDDQSEASGKKSVKGVSKKYVPPRLVPVH 180
Query: 181 YDETEAEREKKRLERAKRRALSSSVIRELKEQYSDAPEEIRDARHPHVTRQSQEDQHRIN 240
YDETEAEREKKRLERAKRRALSSSVIRELKEQYSDAPEEIRDARHPHVTRQSQEDQHRIN
Sbjct: 181 YDETEAEREKKRLERAKRRALSSSVIRELKEQYSDAPEEIRDARHPHVTRQSQEDQHRIN 240
Query: 241 YEESMMVRLSVSKREKGRRKRANVMSSQLHSLTHFSDISALTGGTVHLDEDQNPIKKRKK 300
YEESMMVRLSVSKREKGRRKRANVMSSQLHSLTHFSDISALTGGTVHLDEDQNPIKKRKK
Sbjct: 241 YEESMMVRLSVSKREKGRRKRANVMSSQLHSLTHFSDISALTGGTVHLDEDQNPIKKRKK 300
Query: 301 IPQKGRKKKG 310
IPQKGRKKKG
Sbjct: 301 IPQKGRKKKG 310
>gi|9966799 UTP3, small subunit processome component [Homo sapiens]
Length = 479
Score = 60.8 bits (146), Expect = 1e-09
Identities = 54/233 (23%), Positives = 101/233 (43%), Gaps = 12/233 (5%)
Query: 4 LGVLESDLPSAVTLLKNLQEQVMAVTAQVKSLTQKVQAGAYPTEKGLSFLEVKDQLLLMY 63
L +L + P + L+++L+ ++ V +++ L + V+ G P KG +L K L L Y
Sbjct: 216 LKMLRKESPELLELIEDLKVKLTEVKDELEPLLELVEQGIIPPGKGSQYLRTKYNLYLNY 275
Query: 64 LMDLTHLILDKASGGSLQGHDAVLRLVEIRTVLEKLRPLDQKLKYQIDKLIKTAVTGSLS 123
+++ ++ KA GH + RLV R ++ KL +DQKL +I L+
Sbjct: 276 CSNISFYLILKARRVPAHGHPVIERLVTYRNLINKLSVVDQKLSSEIRHLLTLKDDAVKK 335
Query: 124 ENDP--LRFKPHPSNMMSKLSSEDEEEDEAED-DQSEASGKKSVKGVSKKYVPPRLVPVH 180
E P KP P ++ ++ D ++D D E + K K + + R
Sbjct: 336 ELIPKAKSTKPKPKSVSKTSAAACAVTDLSDDSDFDEKAKLKYYKEIEDRQKLKR----K 391
Query: 181 YDETEAEREKKRLERAKRRALSSSVIRELKEQYSDAPEEIRDARHPHVTRQSQ 233
+E E + + AKR ++ ++ + P + R+P V + +
Sbjct: 392 KEENSTEEQALEDQNAKR-----AITYQIAKNRGLTPRRKKIDRNPRVKHREK 439
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 44.3 bits (103), Expect = 1e-04
Identities = 39/180 (21%), Positives = 75/180 (41%), Gaps = 16/180 (8%)
Query: 109 QIDKLIKTAVTGSLSENDPLRFKPHPSNM-----MSKLSSEDEEEDEAEDDQSEASGKKS 163
Q + ++ + G +S +P + + K+ ED+E EAE + EA ++
Sbjct: 220 QEETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKMEEEDKERAEAERARLEAEERER 279
Query: 164 VKGVSKKYVPPRLVPVHYDETEAEREKKRLERAKRRALSSSVIRELKEQYSDAPEEIRDA 223
+K K + + +E A +E++R E +R + R +E+ EE R A
Sbjct: 280 IKAEQDKKIADERARIEAEEKAAAQERERREAEERERMREEEKRAAEERQRIKEEEKRAA 339
Query: 224 ----RHPHVTRQSQEDQHRINYEESMMV----RLSVSKREKGR---RKRANVMSSQLHSL 272
R +++ E++ RI EE R + EK + +KR + + H++
Sbjct: 340 EERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAM 399
>gi|34878777 ring finger protein 20 [Homo sapiens]
Length = 975
Score = 42.4 bits (98), Expect = 5e-04
Identities = 40/184 (21%), Positives = 83/184 (45%), Gaps = 14/184 (7%)
Query: 91 EIRTVLEKLRPLDQKLKYQIDKLIKTAVTGSLSENDPLRFKPHPSNMMSKLSSEDEEEDE 150
E+R ++ L+ + +LK ++ + K + + S+ + R + + + S+ S+ED +++
Sbjct: 475 EMRHLISSLQNHNHQLKGEVLRY-KRKLREAQSDLNKTRLRSGSALLQSQSSTEDPKDEP 533
Query: 151 AE--DDQSEASGKKSVKGVSKKYVPPRLVPVHYDETEAEREKKRLERAKRRALSSSVIRE 208
AE D + S + S S++ + DE E ERE++ ER + R RE
Sbjct: 534 AELKPDSEDLSSQSSASKASQE--DANEIKSKRDEEERERERREKEREREREREKEKERE 591
Query: 209 LKEQYSDAPEEIRDARHPHVTRQSQEDQHRINYEESMMVRLSVSKREKGRRKRANVMSSQ 268
++Q E+ RD S +D+ + +++ + K+ K K+A +
Sbjct: 592 REKQKLKESEKERD---------SAKDKEKGKHDDGRKKEAEIIKQLKIELKKAQESQKE 642
Query: 269 LHSL 272
+ L
Sbjct: 643 MKLL 646
Score = 32.7 bits (73), Expect = 0.42
Identities = 65/315 (20%), Positives = 121/315 (38%), Gaps = 78/315 (24%)
Query: 7 LESDLPSAVTLLKNL----QEQVMAVTAQVKSLTQKVQAGAYPTEKGLSFLEVKDQLLLM 62
L++ L A TLL Q QV + SL +K++ E L+ + + ++L +
Sbjct: 398 LKAHLDEARTLLHGTRGTHQHQVELIERDEVSLHKKLRTEVIQLEDTLAQVRKEYEMLRI 457
Query: 63 YL--------------MDLTHLILDKASGGSLQGHDAVLRLVEIRTVLEKLRPLDQKL-K 107
++ HLI SLQ H+ L+ E+ KLR L K
Sbjct: 458 EFEQTLAANEQAGPINREMRHLI------SSLQNHNHQLK-GEVLRYKRKLREAQSDLNK 510
Query: 108 YQI---DKLIKTAVTGSLSENDPLRFKPHPSNMMS-----KLSSEDEEEDEAEDDQSEAS 159
++ L+++ + +++P KP ++ S K S ED E +++ D+ E
Sbjct: 511 TRLRSGSALLQSQSSTEDPKDEPAELKPDSEDLSSQSSASKASQEDANEIKSKRDEEERE 570
Query: 160 GKKSVKGVSKKYVPPRLVPVHYDETEAEREKKRLERAKR----------------RALSS 203
++ K ++ + E E EREK++L+ +++ R +
Sbjct: 571 RERREKEREREREREK-------EKEREREKQKLKESEKERDSAKDKEKGKHDDGRKKEA 623
Query: 204 SVIRELK-----------------EQYSDAPEEIRDARHPHVTRQSQEDQHRINYEESMM 246
+I++LK + Y AP+E RD V + E + + E+
Sbjct: 624 EIIKQLKIELKKAQESQKEMKLLLDMYRSAPKEQRD----KVQLMAAEKKSKAELEDLRQ 679
Query: 247 VRLSVSKREKGRRKR 261
+ +EK K+
Sbjct: 680 RLKDLEDKEKKENKK 694
>gi|239508778 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 123
Score = 41.6 bits (96), Expect = 0.001
Identities = 30/121 (24%), Positives = 54/121 (44%), Gaps = 8/121 (6%)
Query: 140 KLSSEDEEEDEAEDDQSEASGKKSVKGVSKKYVPPRLVPVHYDETEAEREKKRLERAKRR 199
K +E+ EE E +++ E GK+ K K+ + ETE +EK+ E+ ++R
Sbjct: 7 KKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKT--KETEKRKEKEEEEKKRKR 64
Query: 200 ALSSSVIRELKEQYSDAPEEIRDARHPHVTRQSQEDQHRINYEESMMVRLSVSKREKGRR 259
E +E+ + EE ++ R+ ++ + R EE K++K RR
Sbjct: 65 KRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEE------EEEKKKKRRR 118
Query: 260 K 260
K
Sbjct: 119 K 119
Score = 35.4 bits (80), Expect = 0.065
Identities = 19/79 (24%), Positives = 37/79 (46%)
Query: 183 ETEAEREKKRLERAKRRALSSSVIRELKEQYSDAPEEIRDARHPHVTRQSQEDQHRINYE 242
E E E+E KR E+ K + ++ KE +E + + ++ +E++ R E
Sbjct: 20 EEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEE 79
Query: 243 ESMMVRLSVSKREKGRRKR 261
E ++E+GRR++
Sbjct: 80 EEEEEEKEEEEKEEGRRRK 98
>gi|116256481 TNFAIP3 interacting protein 1 [Homo sapiens]
Length = 636
Score = 40.8 bits (94), Expect = 0.002
Identities = 43/207 (20%), Positives = 90/207 (43%), Gaps = 24/207 (11%)
Query: 92 IRTVLEKLRPLDQKLKYQIDKLIKTAVTGSLSENDPLRFKPHPSNM-MSKLSSEDEEEDE 150
++T+ E+LR ++ LK ++DK L + D + N+ + KL + ++
Sbjct: 208 LQTLCEQLRKENEALKAKLDK--------GLEQRDQAAERLREENLELKKLLMSNGNKEG 259
Query: 151 AE----DDQSEASGKKSVKGVSKKYVPPRLVPVHYDETEAEREKKRLERAKRRALS---- 202
A + E +GKK+V G + V VP AE++ K LE+ + L
Sbjct: 260 ASGRPGSPKMEGTGKKAVAGQQQASVTAGKVPEVVALGAAEKKVKMLEQQRSELLEVNKQ 319
Query: 203 -SSVIRELKEQYSDAPEEIR----DARHPHVTRQSQEDQHRINYEESMMVRLSVSKREKG 257
R +K+QY E+R D + +++ +Q + +++ +++ S + E+
Sbjct: 320 WDQHFRSMKQQYEQKITELRQKLADLQKQVTDLEAEREQKQRDFDRKLLLAKSKIEMEET 379
Query: 258 RRKRANVMSSQLHSLTHF--SDISALT 282
+++ + +L + +S LT
Sbjct: 380 DKEQLTAEAKELRQKVKYLQDQLSPLT 406
Score = 28.9 bits (63), Expect = 6.1
Identities = 40/171 (23%), Positives = 67/171 (39%), Gaps = 12/171 (7%)
Query: 141 LSSEDEEEDEAEDDQSEASGKKSVKGVSKKYVPPRLVPVHYDETEAEREKKRLERAKRRA 200
L+ E +E + +Q A K+ + V KY+ +L P+ E+E +RL +A A
Sbjct: 369 LAKSKIEMEETDKEQLTAEAKELRQKV--KYLQDQLSPLTRQREYQEKEIQRLNKALEEA 426
Query: 201 LSSSVIRELKEQYSDAPEEIRD--ARHPHVTRQSQEDQHRINYEESMMVRLSVSKREKGR 258
LS +PE + VT+ Q +EE +RE+
Sbjct: 427 LSIQTPPSSPPTAFGSPEGAGALLRKQELVTQNELLKQQVKIFEEDF-------QRERSD 479
Query: 259 RKRANVMSSQLHSLTHFSDISALTGGTVHLDEDQNPIKKRKKIPQKGRKKK 309
R+R N +L + +T L ++ K R+ + Q+ RK K
Sbjct: 480 RERMNEEKEELKKQVEKLQ-AQVTLSNAQLKAFKDEEKAREALRQQKRKAK 529
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 40.8 bits (94), Expect = 0.002
Identities = 43/170 (25%), Positives = 73/170 (42%), Gaps = 14/170 (8%)
Query: 142 SSEDEEEDEAEDDQSEASGKKSVKGVSKKYVPPRLVPVHYDETEAEREKKRLERAKRRAL 201
+ +D E D+ + D+ + G+K K KK P + E A + K+ ER KR
Sbjct: 305 AEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALA-KLKEEEERQKRE-- 361
Query: 202 SSSVIRELKEQYSDAPEE--IRDARHPHVTRQSQEDQHRINYEESMMVRLSVSKREKGRR 259
I+ L+E + EE + + ++ +E + R+ E ++ + S+RE R
Sbjct: 362 EEERIKRLEELEAKRKEEERLEQEKRERKKQKEKERKERLKKEGKLLTK---SQREARAR 418
Query: 260 KRANVMSSQLHSLTHFSDISALTGGTVHLDEDQNPIKKRKKIPQKGRKKK 309
A + Q + S S ++ D KKRKKIPQ+ K+
Sbjct: 419 AEATLKLLQAQGVEVPSKDSLPKKRPIYED------KKRKKIPQQLESKE 462
Score = 29.6 bits (65), Expect = 3.6
Identities = 32/110 (29%), Positives = 44/110 (40%), Gaps = 24/110 (21%)
Query: 143 SEDEEEDEAEDDQSEA------------SGKKSVKGVSKKYVPPRLVPVHYDETEAER-- 188
SE+EEE+E E + SE SGK K SK+ D T+ ER
Sbjct: 547 SEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPSKEMSSDSEYDSDDDRTKEERAY 606
Query: 189 -------EKKRLERAKR---RALSSSVIRELKEQYSDAPEEIRDARHPHV 228
EK+RLE +K L + +I L + + + RH HV
Sbjct: 607 DKAKRRIEKRRLEHSKNVNTEKLRAPIICVLGHVDTGKTKILDKLRHTHV 656
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 40.4 bits (93), Expect = 0.002
Identities = 39/171 (22%), Positives = 75/171 (43%), Gaps = 7/171 (4%)
Query: 92 IRTVLEKLRPLDQKLKYQIDKLIKTAVTGSLSENDPLRFKPHPSNMMSKLSSEDEEEDEA 151
+R EK R +++ +Y+ DK ++ L E R + K E+E + E
Sbjct: 944 LREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREK---KYREEEELQQEE 1000
Query: 152 EDDQSEASGKKSVKGVSKKYVPPRLVPVHYDET-EAEREKKRLERAKRRALSSSVIRELK 210
E E K+ + ++Y + ++ EREK+RL+ +R+ +++ +
Sbjct: 1001 EQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEE 1060
Query: 211 EQYSDAPEEIRDARHPHVTRQSQEDQHRINYEESMMVRLSVSKREKGRRKR 261
EQ E R R + RQ ++++ + EE ++R KR + R+R
Sbjct: 1061 EQLLGEERETR--RRQELERQYRKEE-ELQQEEEQLLREEPEKRRRQERER 1108
Score = 32.3 bits (72), Expect = 0.55
Identities = 50/216 (23%), Positives = 91/216 (42%), Gaps = 31/216 (14%)
Query: 47 EKGLSFLEVKDQLLLMYLMDLTHLILDKASGGSLQGHDAVLRLVEIRTVLEKLRPLDQKL 106
EK L FLE ++QL + LQ + L+ + R ++ R DQK
Sbjct: 828 EKELQFLEEEEQLQR------------RERAQQLQEEEDGLQEDQERRRSQEQRR-DQKW 874
Query: 107 KYQIDKLIKTAVTGSLSENDPLRFKPHPSNMMSKLSSEDEEEDEAEDDQSEASGKKSVKG 166
++Q+++ K L KP + K +EE+E + Q E K+ +
Sbjct: 875 RWQLEEERKR-------RRHTLYAKPALQEQLRKEQQLLQEEEE--ELQREEREKRRRQE 925
Query: 167 VSKKYVPPRLVPVHYDE-TEAEREKKRLERAKRRALSSSVIRELKEQ-YSDAPEEIRDAR 224
++Y + ++ EREK+R + +R+ +++ +EQ + PE+ R
Sbjct: 926 QERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQE 985
Query: 225 HPHVTRQSQEDQHRINYEESMMVRLSVSKREKGRRK 260
R+ +E + EE ++R +REK RR+
Sbjct: 986 REKKYREEEE----LQQEEEQLLR---EEREKRRRQ 1014
Score = 29.3 bits (64), Expect = 4.7
Identities = 29/131 (22%), Positives = 52/131 (39%), Gaps = 13/131 (9%)
Query: 144 EDEEEDEAEDDQSEASGKKSVKGVSKK-----YVPPRLVPVHYDET----EAEREKKRLE 194
ED+E +++ + + + ++ K+ Y P L E E E E +R E
Sbjct: 858 EDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREE 917
Query: 195 RAKRRALSSSVIRELKEQYSDAPEEIRDARHPHVTRQSQEDQHR----INYEESMMVRLS 250
R KRR +EQ E++ RQ +E Q+R + +E ++
Sbjct: 918 REKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEE 977
Query: 251 VSKREKGRRKR 261
KR + R++
Sbjct: 978 PEKRRRQEREK 988
>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
[Homo sapiens]
Length = 624
Score = 39.7 bits (91), Expect = 0.003
Identities = 42/181 (23%), Positives = 70/181 (38%), Gaps = 13/181 (7%)
Query: 129 RFKPHPSNMMSKLSSEDEEEDEAEDDQSEASGKKSVKGVSKKYVPPRLVPVHYDETEAER 188
R K H + + E ++E E E D+S+ +K K K PPR Y+ + R
Sbjct: 437 REKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKD-KKSRTPPR----SYNASRRSR 491
Query: 189 EKKRLERAKRRALSSS----VIRELKEQYSDAPEEIRDARHPHVTRQSQEDQHRINYEES 244
R ER +RR+ SSS + +K + S +P R R+ + D E
Sbjct: 492 SSSR-ERRRRRSRSSSRSPRTSKTIKRKSSRSPSP-RSRNKKDKKREKERDHISERRERE 549
Query: 245 MMVRLSVSKREKGRRKRANVMSSQLHSLTHFSDISALTGGTVHLDEDQNPIKKRKKIPQK 304
+ S ++ +++ S+ L H + + V D+ P + KI
Sbjct: 550 RSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKEV--DDKDAPRTEENKIQHN 607
Query: 305 G 305
G
Sbjct: 608 G 608
>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
[Homo sapiens]
Length = 508
Score = 39.7 bits (91), Expect = 0.003
Identities = 42/181 (23%), Positives = 70/181 (38%), Gaps = 13/181 (7%)
Query: 129 RFKPHPSNMMSKLSSEDEEEDEAEDDQSEASGKKSVKGVSKKYVPPRLVPVHYDETEAER 188
R K H + + E ++E E E D+S+ +K K K PPR Y+ + R
Sbjct: 321 REKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKD-KKSRTPPR----SYNASRRSR 375
Query: 189 EKKRLERAKRRALSSS----VIRELKEQYSDAPEEIRDARHPHVTRQSQEDQHRINYEES 244
R ER +RR+ SSS + +K + S +P R R+ + D E
Sbjct: 376 SSSR-ERRRRRSRSSSRSPRTSKTIKRKSSRSPSP-RSRNKKDKKREKERDHISERRERE 433
Query: 245 MMVRLSVSKREKGRRKRANVMSSQLHSLTHFSDISALTGGTVHLDEDQNPIKKRKKIPQK 304
+ S ++ +++ S+ L H + + V D+ P + KI
Sbjct: 434 RSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKEV--DDKDAPRTEENKIQHN 491
Query: 305 G 305
G
Sbjct: 492 G 492
>gi|41054864 regulating synaptic membrane exocytosis 1 [Homo
sapiens]
Length = 1692
Score = 39.3 bits (90), Expect = 0.005
Identities = 32/149 (21%), Positives = 60/149 (40%), Gaps = 9/149 (6%)
Query: 132 PHPSNMMSKLSSEDEEEDEAEDDQSEASGKKSVKGVSKKYVPPRLVPVHYDETEAEREKK 191
P S+ SE E + SE +GK ++K K+ PV E ER+++
Sbjct: 254 PEQKQASSRSRSEPPRERKKTPGLSEQNGKGALKSERKRVPKTSAQPVEGAVEERERKER 313
Query: 192 RLERAKRRALSSSVIRELKEQYSDAPEEIRDARHPHVTRQSQEDQHRINY-EESMMVRLS 250
R R + S + Y D PE+ + + +Q +E+ ++ Y + + R
Sbjct: 314 RESRRLEKGRS--------QDYPDTPEKRDEGKAADEEKQRKEEDYQTRYRSDPNLARYP 365
Query: 251 VSKREKGRRKRANVMSSQLHSLTHFSDIS 279
V + ++ R + S+ SD++
Sbjct: 366 VKPPPEEQQMRMHARVSRARHERRHSDVA 394
>gi|7662238 apoptotic chromatin condensation inducer 1 [Homo
sapiens]
Length = 1341
Score = 38.1 bits (87), Expect = 0.010
Identities = 32/122 (26%), Positives = 52/122 (42%), Gaps = 7/122 (5%)
Query: 140 KLSSEDEEEDEAEDDQSEASGKKSVKGVSKKYVPPRLVPVHYDETEAEREKKRLERAKRR 199
K E+EEE+E E+D E G +G + P ++ +E E K E R
Sbjct: 268 KTEEEEEEEEEEEEDDEEEEGDD--EGQKSREAP--ILKEFKEEGEEIPRVKPEEMMDER 323
Query: 200 ALSSSVIRELKEQYSDAPEEIRDARHPHVTRQSQEDQHRIN---YEESMMVRLSVSKREK 256
+ S +E+ E+ +AR H+ RQ QE + + EE ++ S +EK
Sbjct: 324 PKTRSQEQEVLERGGRFTRSQEEARKSHLARQQQEKEMKTTSPLEEEEREIKSSQGLKEK 383
Query: 257 GR 258
+
Sbjct: 384 SK 385
Score = 32.0 bits (71), Expect = 0.72
Identities = 31/123 (25%), Positives = 55/123 (44%), Gaps = 9/123 (7%)
Query: 101 PLDQKLKYQIDKLIKTAVTGSLSENDPLRFKPH-PSNMMSKLSSEDEEEDEAEDDQ-SEA 158
P +++ + +++ K VT SEN P P P + ++S++D E ED++ E+
Sbjct: 757 PESERIHHTVEE--KEEVTMDTSENRPENDVPEPPMPIADQVSNDDRPEGSVEDEEKKES 814
Query: 159 SGKKSVKGVSKKYVPPRLVPVHYDETEAEREKKRLERAKRRALSSSVIRELKEQYSDAPE 218
S KS K + VP +TE + + KRR +S+ + K S E
Sbjct: 815 SLPKSFKRKISVVSATKGVPAGNSDTEGGQPGR-----KRRWGASTATTQKKPSISITTE 869
Query: 219 EIR 221
++
Sbjct: 870 SLK 872
Score = 30.4 bits (67), Expect = 2.1
Identities = 26/79 (32%), Positives = 35/79 (44%), Gaps = 2/79 (2%)
Query: 183 ETEAEREKKR-LERAKRRALSSSVIRELKEQYSDAPEEIRDARHPHVTRQSQEDQHRINY 241
E EAERE+ R LER KRR S RE +E+ + RD + +E R
Sbjct: 1264 EKEAERERNRQLEREKRREHSRERDRE-RERERERDRGDRDRDRERDRERGRERDRRDTK 1322
Query: 242 EESMMVRLSVSKREKGRRK 260
S S R++G R+
Sbjct: 1323 RHSRSRSRSTPVRDRGGRR 1341
Score = 30.0 bits (66), Expect = 2.7
Identities = 31/128 (24%), Positives = 51/128 (39%), Gaps = 17/128 (13%)
Query: 140 KLSSEDEEEDEAEDDQSEASGK------KSVKGVSKKYVPPRLVPVHYDETEAEREKKRL 193
+ S++++ ++ E Q E K + K Y P L + EAER ++
Sbjct: 1188 RAKSKEKKSEKKEKAQEEPPAKLLDDLFRKTKAAPCIYWLP-LTDSQIVQKEAERAERAK 1246
Query: 194 ERAKRRALSSSVIRELKEQYSDAPEEIRDARHPHVTRQSQEDQHRINYEESMMVRLSVSK 253
ER KRR KEQ + +E RQ + ++ R + E R +
Sbjct: 1247 EREKRR----------KEQEEEEQKEREKEAERERNRQLEREKRREHSRERDRERERERE 1296
Query: 254 REKGRRKR 261
R++G R R
Sbjct: 1297 RDRGDRDR 1304
>gi|114155142 nuclear pore complex-associated protein TPR [Homo
sapiens]
Length = 2363
Score = 38.1 bits (87), Expect = 0.010
Identities = 29/99 (29%), Positives = 48/99 (48%), Gaps = 14/99 (14%)
Query: 185 EAEREKKRLERAKRRALSS--SVIRELKEQYSDAPEEIRDARHPHVTRQSQEDQHRINYE 242
E E+EK+ L+ KRRA+ S + ELK+ S E+++A T S E Q R + +
Sbjct: 1010 EVEKEKQELQDDKRRAIESMEQQLSELKKTLSSVQNEVQEALQRASTALSNEQQARRDCQ 1069
Query: 243 ESMMVRLSVSKREKGRRKRANVMSSQLHSLTHFSDISAL 281
E +++V + K R+ + H +D+ AL
Sbjct: 1070 E--QAKIAVEAQNKYERE----------LMLHAADVEAL 1096
Score = 32.3 bits (72), Expect = 0.55
Identities = 56/252 (22%), Positives = 104/252 (41%), Gaps = 34/252 (13%)
Query: 4 LGVLESDLPSAVTLLKNL--------QEQVMAVTAQVKSLTQKVQAGAYPTEKGLSFLEV 55
+G LE +L +A LL +E++ A++ ++ + V+ G TE +++E
Sbjct: 346 IGRLEKELENANDLLSATKRKGAILSEEELAAMSPTAAAVAKIVKPGMKLTELYNAYVET 405
Query: 56 KDQLLL---------MYLMDLTHLILDKASGGSLQGHD---AVLRLVEIRTVLEKLRPLD 103
+DQLLL YL ++ + KA Q + A + + LE+
Sbjct: 406 QDQLLLEKLENKRINKYLDEIVKEVEAKAPILKRQREEYERAQKAVASLSVKLEQAMKEI 465
Query: 104 QKLKYQIDKLIKTAVTGSLSENDPLRFKPHPSNMMSKLSSEDEEEDEA-------EDDQS 156
Q+L+ DK K + S+ E D R + ++ ++ E +EA +++ S
Sbjct: 466 QRLQEDTDKANKQS---SVLERDNRRMEIQVKDLSQQIRVLLMELEEARGNHVIRDEEVS 522
Query: 157 EASGKKSVKGVSKKYVPPRLVPVHYDETE----AEREKKRLERAKRRALSSSVIRELKEQ 212
A S + +S+ V R + + + A RE + + +SS I EL+ +
Sbjct: 523 SADISSSSEVISQHLVSYRNIEELQQQNQRLLVALRELGETREREEQETTSSKITELQLK 582
Query: 213 YSDAPEEIRDAR 224
A E+ R
Sbjct: 583 LESALTELEQLR 594
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 37.7 bits (86), Expect = 0.013
Identities = 33/160 (20%), Positives = 68/160 (42%), Gaps = 13/160 (8%)
Query: 141 LSSEDEEEDEAEDDQSEASGKKSVKGVSKKYVPPRLVPVHYDETEAEREKKRLERAKRRA 200
LSSE+EEE E E+++ E ++ + ++ + E + EK+ E+ K++
Sbjct: 2243 LSSEEEEEREEEEEREEEEVREEEEERKEEE----------EGEEKQVEKEEEEKKKKKK 2292
Query: 201 LSSSVIRELKEQYSDAPEEIRDARHPHVTRQSQEDQHRINYEESMMVRLSVSKREKG--- 257
+ KE+ + EEI +E++ + EE + + K+EK
Sbjct: 2293 EKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDREKEILKKEKQFKL 2352
Query: 258 RRKRANVMSSQLHSLTHFSDISALTGGTVHLDEDQNPIKK 297
+ +R + + L+ + G + L ++P+KK
Sbjct: 2353 QEQRRKSLRGRERVLSILRGVPHGKGRAIRLGVLKSPLKK 2392
Score = 35.0 bits (79), Expect = 0.085
Identities = 48/233 (20%), Positives = 93/233 (39%), Gaps = 27/233 (11%)
Query: 93 RTVLEKLRPLDQKLKYQIDKLIKTAVTGSLSENDPLRFKPHPSNMMSKLSSEDEEEDEAE 152
+ + K R L K++ I+K K ++E + + H S++ +DEEE E
Sbjct: 2137 KKLARKQRKLANKMRRMINKEEK------MTEEESKLARKH-----SEVILDDEEEGGIE 2185
Query: 153 DDQSEASGKK---SVKGVSKKYVPPRLVPVHYDETEAER------EKKRLERAKRRALSS 203
+++ K+ K + P DE E+E E E K+ +LSS
Sbjct: 2186 EEEVIPFLKRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSS 2245
Query: 204 SVIRELKEQYSDAPEEIRDARHPHVTRQSQEDQHRINYEESMMVRLSVSKREKGRRK--- 260
E +E+ EE+R+ + E++ EE + K+E+ + K
Sbjct: 2246 EEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEV 2305
Query: 261 ---RANVMS-SQLHSLTHFSDISALTGGTVHLDEDQNPIKKRKKIPQKGRKKK 309
+ +MS + SL+ + +D ++ +KK K+ + +++K
Sbjct: 2306 FEEKEEIMSEEETESLSDEEEEEESCSLEEEVDREKEILKKEKQFKLQEQRRK 2358
>gi|239735592 TRAF2 and NCK interacting kinase isoform 8 [Homo
sapiens]
Length = 1268
Score = 37.7 bits (86), Expect = 0.013
Identities = 40/150 (26%), Positives = 66/150 (44%), Gaps = 27/150 (18%)
Query: 128 LRFKPHPSNMMSKLSSEDE--------EEDEAEDDQSEASGKKSVKGVS---KKYVPPRL 176
++ K H K +DE EE+E E+D E S ++ G S + ++ +L
Sbjct: 300 IQLKDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLPGESTLRRDFLRLQL 359
Query: 177 VPVHYDET----EAEREKKRLERAKRRALSSSV--IRELKEQYSDAPEEIRDARHPHVTR 230
E + E++++ E KR+ L+ I E KEQ E+ R + R
Sbjct: 360 ANKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKE---LR 416
Query: 231 QSQEDQHRINYEESMMVRLSVSKREKGRRK 260
+ QE + R +YEE M +RE+ RR+
Sbjct: 417 KQQEREQRRHYEEQM-------RREEERRR 439
>gi|239735590 TRAF2 and NCK interacting kinase isoform 7 [Homo
sapiens]
Length = 1276
Score = 37.7 bits (86), Expect = 0.013
Identities = 40/150 (26%), Positives = 66/150 (44%), Gaps = 27/150 (18%)
Query: 128 LRFKPHPSNMMSKLSSEDE--------EEDEAEDDQSEASGKKSVKGVS---KKYVPPRL 176
++ K H K +DE EE+E E+D E S ++ G S + ++ +L
Sbjct: 300 IQLKDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLPGESTLRRDFLRLQL 359
Query: 177 VPVHYDET----EAEREKKRLERAKRRALSSSV--IRELKEQYSDAPEEIRDARHPHVTR 230
E + E++++ E KR+ L+ I E KEQ E+ R + R
Sbjct: 360 ANKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKE---LR 416
Query: 231 QSQEDQHRINYEESMMVRLSVSKREKGRRK 260
+ QE + R +YEE M +RE+ RR+
Sbjct: 417 KQQEREQRRHYEEQM-------RREEERRR 439
>gi|239735588 TRAF2 and NCK interacting kinase isoform 6 [Homo
sapiens]
Length = 1297
Score = 37.7 bits (86), Expect = 0.013
Identities = 40/150 (26%), Positives = 66/150 (44%), Gaps = 27/150 (18%)
Query: 128 LRFKPHPSNMMSKLSSEDE--------EEDEAEDDQSEASGKKSVKGVS---KKYVPPRL 176
++ K H K +DE EE+E E+D E S ++ G S + ++ +L
Sbjct: 300 IQLKDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLPGESTLRRDFLRLQL 359
Query: 177 VPVHYDET----EAEREKKRLERAKRRALSSSV--IRELKEQYSDAPEEIRDARHPHVTR 230
E + E++++ E KR+ L+ I E KEQ E+ R + R
Sbjct: 360 ANKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKE---LR 416
Query: 231 QSQEDQHRINYEESMMVRLSVSKREKGRRK 260
+ QE + R +YEE M +RE+ RR+
Sbjct: 417 KQQEREQRRHYEEQM-------RREEERRR 439
>gi|239735586 TRAF2 and NCK interacting kinase isoform 5 [Homo
sapiens]
Length = 1305
Score = 37.7 bits (86), Expect = 0.013
Identities = 40/150 (26%), Positives = 66/150 (44%), Gaps = 27/150 (18%)
Query: 128 LRFKPHPSNMMSKLSSEDE--------EEDEAEDDQSEASGKKSVKGVS---KKYVPPRL 176
++ K H K +DE EE+E E+D E S ++ G S + ++ +L
Sbjct: 300 IQLKDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLPGESTLRRDFLRLQL 359
Query: 177 VPVHYDET----EAEREKKRLERAKRRALSSSV--IRELKEQYSDAPEEIRDARHPHVTR 230
E + E++++ E KR+ L+ I E KEQ E+ R + R
Sbjct: 360 ANKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKE---LR 416
Query: 231 QSQEDQHRINYEESMMVRLSVSKREKGRRK 260
+ QE + R +YEE M +RE+ RR+
Sbjct: 417 KQQEREQRRHYEEQM-------RREEERRR 439
>gi|239735584 TRAF2 and NCK interacting kinase isoform 4 [Homo
sapiens]
Length = 1323
Score = 37.7 bits (86), Expect = 0.013
Identities = 40/150 (26%), Positives = 66/150 (44%), Gaps = 27/150 (18%)
Query: 128 LRFKPHPSNMMSKLSSEDE--------EEDEAEDDQSEASGKKSVKGVS---KKYVPPRL 176
++ K H K +DE EE+E E+D E S ++ G S + ++ +L
Sbjct: 300 IQLKDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLPGESTLRRDFLRLQL 359
Query: 177 VPVHYDET----EAEREKKRLERAKRRALSSSV--IRELKEQYSDAPEEIRDARHPHVTR 230
E + E++++ E KR+ L+ I E KEQ E+ R + R
Sbjct: 360 ANKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKE---LR 416
Query: 231 QSQEDQHRINYEESMMVRLSVSKREKGRRK 260
+ QE + R +YEE M +RE+ RR+
Sbjct: 417 KQQEREQRRHYEEQM-------RREEERRR 439
>gi|239735582 TRAF2 and NCK interacting kinase isoform 3 [Homo
sapiens]
Length = 1331
Score = 37.7 bits (86), Expect = 0.013
Identities = 40/150 (26%), Positives = 66/150 (44%), Gaps = 27/150 (18%)
Query: 128 LRFKPHPSNMMSKLSSEDE--------EEDEAEDDQSEASGKKSVKGVS---KKYVPPRL 176
++ K H K +DE EE+E E+D E S ++ G S + ++ +L
Sbjct: 300 IQLKDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLPGESTLRRDFLRLQL 359
Query: 177 VPVHYDET----EAEREKKRLERAKRRALSSSV--IRELKEQYSDAPEEIRDARHPHVTR 230
E + E++++ E KR+ L+ I E KEQ E+ R + R
Sbjct: 360 ANKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKE---LR 416
Query: 231 QSQEDQHRINYEESMMVRLSVSKREKGRRK 260
+ QE + R +YEE M +RE+ RR+
Sbjct: 417 KQQEREQRRHYEEQM-------RREEERRR 439
>gi|239735580 TRAF2 and NCK interacting kinase isoform 2 [Homo
sapiens]
Length = 1352
Score = 37.7 bits (86), Expect = 0.013
Identities = 40/150 (26%), Positives = 66/150 (44%), Gaps = 27/150 (18%)
Query: 128 LRFKPHPSNMMSKLSSEDE--------EEDEAEDDQSEASGKKSVKGVS---KKYVPPRL 176
++ K H K +DE EE+E E+D E S ++ G S + ++ +L
Sbjct: 300 IQLKDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLPGESTLRRDFLRLQL 359
Query: 177 VPVHYDET----EAEREKKRLERAKRRALSSSV--IRELKEQYSDAPEEIRDARHPHVTR 230
E + E++++ E KR+ L+ I E KEQ E+ R + R
Sbjct: 360 ANKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKE---LR 416
Query: 231 QSQEDQHRINYEESMMVRLSVSKREKGRRK 260
+ QE + R +YEE M +RE+ RR+
Sbjct: 417 KQQEREQRRHYEEQM-------RREEERRR 439
>gi|55741807 TRAF2 and NCK interacting kinase isoform 1 [Homo
sapiens]
Length = 1360
Score = 37.7 bits (86), Expect = 0.013
Identities = 40/150 (26%), Positives = 66/150 (44%), Gaps = 27/150 (18%)
Query: 128 LRFKPHPSNMMSKLSSEDE--------EEDEAEDDQSEASGKKSVKGVS---KKYVPPRL 176
++ K H K +DE EE+E E+D E S ++ G S + ++ +L
Sbjct: 300 IQLKDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLPGESTLRRDFLRLQL 359
Query: 177 VPVHYDET----EAEREKKRLERAKRRALSSSV--IRELKEQYSDAPEEIRDARHPHVTR 230
E + E++++ E KR+ L+ I E KEQ E+ R + R
Sbjct: 360 ANKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKE---LR 416
Query: 231 QSQEDQHRINYEESMMVRLSVSKREKGRRK 260
+ QE + R +YEE M +RE+ RR+
Sbjct: 417 KQQEREQRRHYEEQM-------RREEERRR 439
>gi|218505787 protocadherin 15 isoform CD2-1 precursor [Homo sapiens]
Length = 1790
Score = 37.4 bits (85), Expect = 0.017
Identities = 40/174 (22%), Positives = 71/174 (40%), Gaps = 20/174 (11%)
Query: 71 ILDKASGGSLQGHDAVLRLVEIRTVLEKLRPLDQKLKYQIDKLIKTAVTGSLSENDPLRF 130
+ DK L+G + RL E KL LDQ+ + T + S +D +
Sbjct: 1561 LADKRGIVDLEGEEWQRRLEEEDKDYLKLT-LDQE-----EATESTVESEEESSSDYTEY 1614
Query: 131 KPHPSNMMSKLSSEDEEEDEAEDDQSEASGKKSVKGVSKKYVPPRLVPVHYDETEAEREK 190
S ++E+E E E ++ E+S +S + S E+E E+ +
Sbjct: 1615 SEEESEFSESETTEEESESETPSEEEESSTPESEESEST-------------ESEGEKAR 1661
Query: 191 KRLERAKRRALSSSVIRELKEQYSDAPEEIRDARHPHVTRQSQEDQHRINYEES 244
K + A+RR + V +E+K + + EE ++ + +E+ EES
Sbjct: 1662 KNIVLARRRPMVEEV-KEVKGRKEEPQEEQKEPKMEEEEHSEEEESGPAPVEES 1714
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 37.0 bits (84), Expect = 0.022
Identities = 31/135 (22%), Positives = 54/135 (40%), Gaps = 10/135 (7%)
Query: 131 KPHPSNMMSKLSSEDEEEDEAEDDQSEASGKKSVKGVSKKYVPPRLVPVHYDET----EA 186
K S + ++ + E E ++ GKK KG KK R E E
Sbjct: 53 KERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEK 112
Query: 187 EREKKRLERAKRRALSSSVIRELKEQYSDAPEEIRDARHPHVTRQSQEDQHRINYEESMM 246
E+ KK+ ++ + R RE KE E R+ R ++ + ++ R E
Sbjct: 113 EKRKKKEKKERGRTSKEGKERERKE------ERKREERKERERKKEEREKERERKERKKR 166
Query: 247 VRLSVSKREKGRRKR 261
R V ++E+ R+++
Sbjct: 167 ERKQVGEKEEERKEK 181
Score = 32.7 bits (73), Expect = 0.42
Identities = 28/123 (22%), Positives = 58/123 (47%), Gaps = 4/123 (3%)
Query: 140 KLSSEDEEEDEAEDDQSEASGKKSVKGVSK--KYVPPRLVPVHYDETEAEREKKRLERAK 197
K + E EE+++ + + + G+ S +G + K R + + EREK+R ER +
Sbjct: 104 KENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKER-ERKE 162
Query: 198 RRALSSSVIRELKEQYSDAPEEIRDARHPHVTRQSQEDQHRINYEESMMVRLSVSKREKG 257
R+ + E +E+ + + R R + ++ ++++ R E R +R+K
Sbjct: 163 RKKRERKQVGEKEEERKEKERKERKKRERN-RKERKKERERKERRERKKERKKKEERKKE 221
Query: 258 RRK 260
R+K
Sbjct: 222 RQK 224
Score = 30.0 bits (66), Expect = 2.7
Identities = 27/123 (21%), Positives = 51/123 (41%), Gaps = 13/123 (10%)
Query: 139 SKLSSEDEEEDEAEDDQSEASGKKSVKGVSKKYVPPRLVPVHYDETEAEREKKRLERAKR 198
++ + E E E + ++ E +K + +K + E + ER+K+ ER KR
Sbjct: 47 TRKEGKKERESERKKERREREKRKREREKERKRERGK------KEKKGERKKEERERKKR 100
Query: 199 RALSSSVIRELKEQYSDAPEEIRDARHPHVTRQSQEDQHRINYEESMMVRLSVSKREKGR 258
R RE + + + E+ + R S+E + R EE +R+K
Sbjct: 101 R-------REKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEE 153
Query: 259 RKR 261
R++
Sbjct: 154 REK 156
Score = 28.9 bits (63), Expect = 6.1
Identities = 25/118 (21%), Positives = 49/118 (41%), Gaps = 15/118 (12%)
Query: 144 EDEEEDEAEDDQSEASGKKSVKGVSKKYVPPRLVPVHYDETEAEREKKRLERAKRRALSS 203
E +E + ++++ + +K K +K V ++ E +EK+R ER KR
Sbjct: 143 ERKERERKKEEREKERERKERKKRERKQVG--------EKEEERKEKERKERKKRE---- 190
Query: 204 SVIRELKEQYSDAPEEIRDARHPHVTRQSQEDQHRINYEESMMVRLSVSKREKGRRKR 261
R KE+ + + R R ++ + + R ++ KRE+ RK+
Sbjct: 191 ---RNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKERKK 245
>gi|56090620 NFKB activating protein-like [Homo sapiens]
Length = 402
Score = 37.0 bits (84), Expect = 0.022
Identities = 33/143 (23%), Positives = 59/143 (41%), Gaps = 10/143 (6%)
Query: 171 YVPPRLVPVHYDETEAEREKKRLERAKRRALSSSVIRELKEQY----SDAPEEIRDARHP 226
Y R Y++ E+ R+++ ER + L + + ++ SD + D
Sbjct: 101 YAEERQSAEDYEKEESHRQRRLKERERIGELGAPEVWGPSPKFPQLDSDEHTPVEDEEEV 160
Query: 227 HVTRQSQEDQHRINYEESMMVRLSVSKREKGRRKRANVMSSQLHSLTHFSDISALTGGTV 286
+ S D N EE R + R + ++KR N S + H SD ++ +
Sbjct: 161 THQKSSSSDS---NSEEH---RKKKTSRSRNKKKRKNKSSKRKHRKYSDSDSNSESDTNS 214
Query: 287 HLDEDQNPIKKRKKIPQKGRKKK 309
D+D+ +K +KK +K K K
Sbjct: 215 DSDDDKKRVKAKKKKKKKKHKTK 237
>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
sapiens]
Length = 1938
Score = 36.6 bits (83), Expect = 0.029
Identities = 57/284 (20%), Positives = 120/284 (42%), Gaps = 25/284 (8%)
Query: 2 AALGVLESDLPSAVTLLKNLQEQVMAVTAQVKSLTQKVQAGAYPTEKGLSFLEVKDQLLL 61
A + LE ++ + TL +++Q + +++ ++++++ + T + + ++
Sbjct: 1117 ARIEELEEEIEAEHTLRAKIEKQRSDLARELEEISERLEEASGATSAQIEMNKKREAEFQ 1176
Query: 62 MYLMDLTHLILD-KASGGSLQGH--DAVLRLVE----IRTVLEKLRPLDQKLKYQIDKLI 114
DL L +A+ +L+ D+V L E ++ V +KL +LK +ID +
Sbjct: 1177 KMRRDLEEATLQHEATAATLRKKQADSVAELGEQIDNLQRVKQKLEKEKSELKMEIDDMA 1236
Query: 115 KTAVTGSLSENDPLRFKPHPSNMMSKLSSEDEEEDEAEDDQS-------EASGKKSVKGV 167
S S+++ R + S++ ++DE++ + D + +G+ S +
Sbjct: 1237 SNIEALSKSKSNIERTCRTVEDQFSEIKAKDEQQTQLIHDLNMQKARLQTQNGELSHRVE 1296
Query: 168 SKKYVPPRLVPVHYDETEAEREKKR-------LERAKRRALSSS--VIRELKEQYSDAPE 218
K+ + +L T+ E KR + A AL SS L+EQY + E
Sbjct: 1297 EKESLISQLTKSKQALTQQLEELKRQMEEETKAKNAMAHALQSSRHDCDLLREQYEEEQE 1356
Query: 219 EIRDARHPHVTRQSQEDQHRINYEESMMVRLSVSKREKGRRKRA 262
+ + S+ Q R YE + R + E+ ++K A
Sbjct: 1357 AKAELQRALSKANSEVAQWRTKYETDAIQR--TEELEEAKKKLA 1398
>gi|169166558 PREDICTED: similar to hCG18094 [Homo sapiens]
Length = 459
Score = 35.8 bits (81), Expect = 0.050
Identities = 43/178 (24%), Positives = 80/178 (44%), Gaps = 23/178 (12%)
Query: 100 RPLDQKLKYQIDKLIKTAVTGSLSENDPLRFKPHPSNMMSKLSSEDEEEDEAEDDQSEAS 159
R ++Q+L+ ++DKL+ A G SE K+ ++D EE A +
Sbjct: 56 RQVEQELQ-RVDKLVDGA--GDFSEF---------FEWQKKMQAKDREEQLAASECRRLQ 103
Query: 160 GKKSVKGVSKKYVPPRLVPVHYDETEAEREKKR-----LERAKRRALSSSVIRELKEQYS 214
GK S ++ V R + ++ E++K++ L+RA+RR +EL EQ
Sbjct: 104 GKLS----HEEAVLARQSLMQENKQRVEQQKEQMAKLMLQRAERRLREDRSRKELVEQVI 159
Query: 215 DAPEEIRDARHPHVTRQSQEDQHRINYEESMMVRLSVSKREKGRRKRANVMSSQLHSL 272
+ + + A+ + Q Q I ++ R + + +E+ RR+ + SQL +L
Sbjct: 160 EGQKNAKAAQTKLAKGRQQTVQEAIEESRGLLQRRAQAAQEEQRRRCE--LISQLRAL 215
>gi|169167297 PREDICTED: similar to hCG18094 [Homo sapiens]
Length = 459
Score = 35.8 bits (81), Expect = 0.050
Identities = 43/178 (24%), Positives = 80/178 (44%), Gaps = 23/178 (12%)
Query: 100 RPLDQKLKYQIDKLIKTAVTGSLSENDPLRFKPHPSNMMSKLSSEDEEEDEAEDDQSEAS 159
R ++Q+L+ ++DKL+ A G SE K+ ++D EE A +
Sbjct: 56 RQVEQELQ-RVDKLVDGA--GDFSEF---------FEWQKKMQAKDREEQLAASECRRLQ 103
Query: 160 GKKSVKGVSKKYVPPRLVPVHYDETEAEREKKR-----LERAKRRALSSSVIRELKEQYS 214
GK S ++ V R + ++ E++K++ L+RA+RR +EL EQ
Sbjct: 104 GKLS----HEEAVLARQSLMQENKQRVEQQKEQMAKLMLQRAERRLREDRSRKELVEQVI 159
Query: 215 DAPEEIRDARHPHVTRQSQEDQHRINYEESMMVRLSVSKREKGRRKRANVMSSQLHSL 272
+ + + A+ + Q Q I ++ R + + +E+ RR+ + SQL +L
Sbjct: 160 EGQKNAKAAQTKLAKGRQQTVQEAIEESRGLLQRRAQAAQEEQRRRCE--LISQLRAL 215
>gi|169166473 PREDICTED: similar to hCG18094 [Homo sapiens]
Length = 459
Score = 35.8 bits (81), Expect = 0.050
Identities = 43/178 (24%), Positives = 80/178 (44%), Gaps = 23/178 (12%)
Query: 100 RPLDQKLKYQIDKLIKTAVTGSLSENDPLRFKPHPSNMMSKLSSEDEEEDEAEDDQSEAS 159
R ++Q+L+ ++DKL+ A G SE K+ ++D EE A +
Sbjct: 56 RQVEQELQ-RVDKLVDGA--GDFSEF---------FEWQKKMQAKDREEQLAASECRRLQ 103
Query: 160 GKKSVKGVSKKYVPPRLVPVHYDETEAEREKKR-----LERAKRRALSSSVIRELKEQYS 214
GK S ++ V R + ++ E++K++ L+RA+RR +EL EQ
Sbjct: 104 GKLS----HEEAVLARQSLMQENKQRVEQQKEQMAKLMLQRAERRLREDRSRKELVEQVI 159
Query: 215 DAPEEIRDARHPHVTRQSQEDQHRINYEESMMVRLSVSKREKGRRKRANVMSSQLHSL 272
+ + + A+ + Q Q I ++ R + + +E+ RR+ + SQL +L
Sbjct: 160 EGQKNAKAAQTKLAKGRQQTVQEAIEESRGLLQRRAQAAQEEQRRRCE--LISQLRAL 215
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.128 0.338
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,908,285
Number of Sequences: 37866
Number of extensions: 465499
Number of successful extensions: 5410
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 49
Number of HSP's successfully gapped in prelim test: 340
Number of HSP's that attempted gapping in prelim test: 4519
Number of HSP's gapped (non-prelim): 918
length of query: 311
length of database: 18,247,518
effective HSP length: 102
effective length of query: 209
effective length of database: 14,385,186
effective search space: 3006503874
effective search space used: 3006503874
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.