Guide to the Human Genome
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Search of human proteins with 169161936

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|169161936 PREDICTED: hypothetical protein [Homo sapiens]
         (220 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|169162451 PREDICTED: hypothetical protein [Homo sapiens]           450   e-127
gi|169161936 PREDICTED: hypothetical protein [Homo sapiens]           450   e-127
gi|169162699 PREDICTED: hypothetical protein [Homo sapiens]           450   e-127
gi|195927056 alkB, alkylation repair homolog 8 [Homo sapiens]         317   7e-87
gi|77695912 TIA-1 related protein isoform 2 [Homo sapiens]             33   0.25 
gi|4507499 TIA-1 related protein isoform 1 [Homo sapiens]              33   0.25 
gi|188219593 TIA1 protein isoform 1 [Homo sapiens]                     31   0.95 
gi|188219591 TIA1 protein isoform 2 [Homo sapiens]                     31   0.95 
gi|16905073 SoxLZ/Sox6 leucine zipper binding protein [Homo sapi...    31   0.95 
gi|127138957 zinc finger protein 537 [Homo sapiens]                    30   1.6  
gi|157388975 coiled-coil domain containing 99 [Homo sapiens]           30   2.1  
gi|163659918 sacsin [Homo sapiens]                                     28   4.7  
gi|54112394 calcium channel, voltage-dependent, alpha 2/delta su...    28   4.7  
gi|54112392 calcium channel, voltage-dependent, alpha 2/delta su...    28   4.7  
gi|221316689 cytidine triphosphate synthase II [Homo sapiens]          28   4.7  
gi|28559085 cytidine triphosphate synthase II [Homo sapiens]           28   4.7  
gi|28559083 cytidine triphosphate synthase II [Homo sapiens]           28   4.7  
gi|194018497 FYVE, RhoGEF and PH domain containing 5 [Homo sapiens]    28   4.7  
gi|54112390 calcium channel, voltage-dependent, alpha 2/delta su...    28   6.1  
gi|50962882 G patch domain containing 8 [Homo sapiens]                 28   6.1  
gi|38569394 inhibitor of kappa light polypeptide gene enhancer i...    28   8.0  

>gi|169162451 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 220

 Score =  450 bits (1158), Expect = e-127
 Identities = 220/220 (100%), Positives = 220/220 (100%)

Query: 1   MGTAEAAGNEEKEEASKVILSAEEERLVVASVGLGNGVSRNQLLLVLEKCGLVDALLMPP 60
           MGTAEAAGNEEKEEASKVILSAEEERLVVASVGLGNGVSRNQLLLVLEKCGLVDALLMPP
Sbjct: 1   MGTAEAAGNEEKEEASKVILSAEEERLVVASVGLGNGVSRNQLLLVLEKCGLVDALLMPP 60

Query: 61  YKPYSFERYKTTEESKRAYVTLNGKEIVDDLGQKMILYLNFVEKAQWKELGPQALPLVLI 120
           YKPYSFERYKTTEESKRAYVTLNGKEIVDDLGQKMILYLNFVEKAQWKELGPQALPLVLI
Sbjct: 61  YKPYSFERYKTTEESKRAYVTLNGKEIVDDLGQKMILYLNFVEKAQWKELGPQALPLVLI 120

Query: 121 VVEEIISTEDEKILLESVDQTKDTDHQNFQKCLKHRRVKHFGYEFHCEKNNVDKDKHLPR 180
           VVEEIISTEDEKILLESVDQTKDTDHQNFQKCLKHRRVKHFGYEFHCEKNNVDKDKHLPR
Sbjct: 121 VVEEIISTEDEKILLESVDQTKDTDHQNFQKCLKHRRVKHFGYEFHCEKNNVDKDKHLPR 180

Query: 181 GLLDVCDSFLEKWLREGYIKHKPEQLTINQYEPGHDCHGF 220
           GLLDVCDSFLEKWLREGYIKHKPEQLTINQYEPGHDCHGF
Sbjct: 181 GLLDVCDSFLEKWLREGYIKHKPEQLTINQYEPGHDCHGF 220


>gi|169161936 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 220

 Score =  450 bits (1158), Expect = e-127
 Identities = 220/220 (100%), Positives = 220/220 (100%)

Query: 1   MGTAEAAGNEEKEEASKVILSAEEERLVVASVGLGNGVSRNQLLLVLEKCGLVDALLMPP 60
           MGTAEAAGNEEKEEASKVILSAEEERLVVASVGLGNGVSRNQLLLVLEKCGLVDALLMPP
Sbjct: 1   MGTAEAAGNEEKEEASKVILSAEEERLVVASVGLGNGVSRNQLLLVLEKCGLVDALLMPP 60

Query: 61  YKPYSFERYKTTEESKRAYVTLNGKEIVDDLGQKMILYLNFVEKAQWKELGPQALPLVLI 120
           YKPYSFERYKTTEESKRAYVTLNGKEIVDDLGQKMILYLNFVEKAQWKELGPQALPLVLI
Sbjct: 61  YKPYSFERYKTTEESKRAYVTLNGKEIVDDLGQKMILYLNFVEKAQWKELGPQALPLVLI 120

Query: 121 VVEEIISTEDEKILLESVDQTKDTDHQNFQKCLKHRRVKHFGYEFHCEKNNVDKDKHLPR 180
           VVEEIISTEDEKILLESVDQTKDTDHQNFQKCLKHRRVKHFGYEFHCEKNNVDKDKHLPR
Sbjct: 121 VVEEIISTEDEKILLESVDQTKDTDHQNFQKCLKHRRVKHFGYEFHCEKNNVDKDKHLPR 180

Query: 181 GLLDVCDSFLEKWLREGYIKHKPEQLTINQYEPGHDCHGF 220
           GLLDVCDSFLEKWLREGYIKHKPEQLTINQYEPGHDCHGF
Sbjct: 181 GLLDVCDSFLEKWLREGYIKHKPEQLTINQYEPGHDCHGF 220


>gi|169162699 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 220

 Score =  450 bits (1158), Expect = e-127
 Identities = 220/220 (100%), Positives = 220/220 (100%)

Query: 1   MGTAEAAGNEEKEEASKVILSAEEERLVVASVGLGNGVSRNQLLLVLEKCGLVDALLMPP 60
           MGTAEAAGNEEKEEASKVILSAEEERLVVASVGLGNGVSRNQLLLVLEKCGLVDALLMPP
Sbjct: 1   MGTAEAAGNEEKEEASKVILSAEEERLVVASVGLGNGVSRNQLLLVLEKCGLVDALLMPP 60

Query: 61  YKPYSFERYKTTEESKRAYVTLNGKEIVDDLGQKMILYLNFVEKAQWKELGPQALPLVLI 120
           YKPYSFERYKTTEESKRAYVTLNGKEIVDDLGQKMILYLNFVEKAQWKELGPQALPLVLI
Sbjct: 61  YKPYSFERYKTTEESKRAYVTLNGKEIVDDLGQKMILYLNFVEKAQWKELGPQALPLVLI 120

Query: 121 VVEEIISTEDEKILLESVDQTKDTDHQNFQKCLKHRRVKHFGYEFHCEKNNVDKDKHLPR 180
           VVEEIISTEDEKILLESVDQTKDTDHQNFQKCLKHRRVKHFGYEFHCEKNNVDKDKHLPR
Sbjct: 121 VVEEIISTEDEKILLESVDQTKDTDHQNFQKCLKHRRVKHFGYEFHCEKNNVDKDKHLPR 180

Query: 181 GLLDVCDSFLEKWLREGYIKHKPEQLTINQYEPGHDCHGF 220
           GLLDVCDSFLEKWLREGYIKHKPEQLTINQYEPGHDCHGF
Sbjct: 181 GLLDVCDSFLEKWLREGYIKHKPEQLTINQYEPGHDCHGF 220


>gi|195927056 alkB, alkylation repair homolog 8 [Homo sapiens]
          Length = 664

 Score =  317 bits (811), Expect = 7e-87
 Identities = 156/195 (80%), Positives = 173/195 (88%)

Query: 20  LSAEEERLVVASVGLGNGVSRNQLLLVLEKCGLVDALLMPPYKPYSFERYKTTEESKRAY 79
           +S   + LVVA+ GLGNGVSRNQLL VLEKCGLVDALLMPP KPYSF RY+TTEESKRAY
Sbjct: 38  VSYATQSLVVANGGLGNGVSRNQLLPVLEKCGLVDALLMPPNKPYSFARYRTTEESKRAY 97

Query: 80  VTLNGKEIVDDLGQKMILYLNFVEKAQWKELGPQALPLVLIVVEEIISTEDEKILLESVD 139
           VTLNGKE+VDDLGQK+ LYLNFVEK QWKEL PQALP  L+VVEEIIS+E+EK+LLESVD
Sbjct: 98  VTLNGKEVVDDLGQKITLYLNFVEKVQWKELRPQALPPGLMVVEEIISSEEEKMLLESVD 157

Query: 140 QTKDTDHQNFQKCLKHRRVKHFGYEFHCEKNNVDKDKHLPRGLLDVCDSFLEKWLREGYI 199
            T+DTD+QN QK LKHRRVKHFGYEFH E NNVDKDK L  GL D+C+SFLEKWLR+GYI
Sbjct: 158 WTEDTDNQNSQKSLKHRRVKHFGYEFHYENNNVDKDKPLSGGLPDICESFLEKWLRKGYI 217

Query: 200 KHKPEQLTINQYEPG 214
           KHKP+Q+TINQYEPG
Sbjct: 218 KHKPDQMTINQYEPG 232


>gi|77695912 TIA-1 related protein isoform 2 [Homo sapiens]
          Length = 392

 Score = 32.7 bits (73), Expect = 0.25
 Identities = 19/79 (24%), Positives = 36/79 (45%)

Query: 9   NEEKEEASKVILSAEEERLVVASVGLGNGVSRNQLLLVLEKCGLVDALLMPPYKPYSFER 68
           N ++     V+  +  +   V   G+ +G++   +       G +  + + P K YSF R
Sbjct: 204 NTKQLRFEDVVNQSSPKNCTVYCGGIASGLTDQLMRQTFSPFGQIMEIRVFPEKGYSFVR 263

Query: 69  YKTTEESKRAYVTLNGKEI 87
           + T E +  A V++NG  I
Sbjct: 264 FSTHESAAHAIVSVNGTTI 282


>gi|4507499 TIA-1 related protein isoform 1 [Homo sapiens]
          Length = 375

 Score = 32.7 bits (73), Expect = 0.25
 Identities = 19/79 (24%), Positives = 36/79 (45%)

Query: 9   NEEKEEASKVILSAEEERLVVASVGLGNGVSRNQLLLVLEKCGLVDALLMPPYKPYSFER 68
           N ++     V+  +  +   V   G+ +G++   +       G +  + + P K YSF R
Sbjct: 187 NTKQLRFEDVVNQSSPKNCTVYCGGIASGLTDQLMRQTFSPFGQIMEIRVFPEKGYSFVR 246

Query: 69  YKTTEESKRAYVTLNGKEI 87
           + T E +  A V++NG  I
Sbjct: 247 FSTHESAAHAIVSVNGTTI 265


>gi|188219593 TIA1 protein isoform 1 [Homo sapiens]
          Length = 375

 Score = 30.8 bits (68), Expect = 0.95
 Identities = 18/79 (22%), Positives = 36/79 (45%)

Query: 9   NEEKEEASKVILSAEEERLVVASVGLGNGVSRNQLLLVLEKCGLVDALLMPPYKPYSFER 68
           N ++    +V+  +      V   G+ +G++   +       G +  + + P K YSF R
Sbjct: 185 NTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPDKGYSFVR 244

Query: 69  YKTTEESKRAYVTLNGKEI 87
           + + E +  A V++NG  I
Sbjct: 245 FNSHESAAHAIVSVNGTTI 263


>gi|188219591 TIA1 protein isoform 2 [Homo sapiens]
          Length = 386

 Score = 30.8 bits (68), Expect = 0.95
 Identities = 18/79 (22%), Positives = 36/79 (45%)

Query: 9   NEEKEEASKVILSAEEERLVVASVGLGNGVSRNQLLLVLEKCGLVDALLMPPYKPYSFER 68
           N ++    +V+  +      V   G+ +G++   +       G +  + + P K YSF R
Sbjct: 196 NTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPDKGYSFVR 255

Query: 69  YKTTEESKRAYVTLNGKEI 87
           + + E +  A V++NG  I
Sbjct: 256 FNSHESAAHAIVSVNGTTI 274


>gi|16905073 SoxLZ/Sox6 leucine zipper binding protein [Homo
           sapiens]
          Length = 269

 Score = 30.8 bits (68), Expect = 0.95
 Identities = 22/97 (22%), Positives = 46/97 (47%), Gaps = 6/97 (6%)

Query: 67  ERYKTTEESKRAYVTLNGKEIVDDLGQKMILYLNF----VEKAQWKELGPQALPLVLIVV 122
           E +K  EE +     +  + + D   Q  +L +       E +QW++  P+ +PL   V+
Sbjct: 30  EMWKDMEECQNKLSLIGTETLTDSNAQLSLLIMQVKCLTAELSQWQKKTPETIPLTEDVL 89

Query: 123 EEIISTEDEKIL--LESVDQTKDTDHQNFQKCLKHRR 157
             +   E +K+   LE V  TK++ ++  ++ L+  +
Sbjct: 90  ITLGKEEFQKLRQDLEMVLSTKESKNEKLKEDLEREQ 126


>gi|127138957 zinc finger protein 537 [Homo sapiens]
          Length = 1081

 Score = 30.0 bits (66), Expect = 1.6
 Identities = 14/41 (34%), Positives = 19/41 (46%)

Query: 70  KTTEESKRAYVTLNGKEIVDDLGQKMILYLNFVEKAQWKEL 110
           K  EE+K   V L    + D L Q   +Y NF+  + W  L
Sbjct: 94  KNEEETKEVTVPLEDTTVSDSLEQMKAVYNNFLSNSYWSNL 134


>gi|157388975 coiled-coil domain containing 99 [Homo sapiens]
          Length = 605

 Score = 29.6 bits (65), Expect = 2.1
 Identities = 31/126 (24%), Positives = 55/126 (43%), Gaps = 6/126 (4%)

Query: 22  AEEERLVVASVGLGNGVSRNQLLLVLEKCGLVDALLMPPYKPYSFERYKTTEESKRAYVT 81
           AEEERL  A  GL    S+N+L   L+KC      +   Y+   +   +  E   R   +
Sbjct: 16  AEEERLKAAQYGLQLVESQNELQNQLDKCRNEMMTMTESYEQEKYTLQREVELKSRMLES 75

Query: 82  LNGKEIVDDLGQKMILYLNFVE----KAQWKELGPQALPLVLIVVEEIISTEDEKILLES 137
           L+ +   + + Q+  ++L  +E    ++  +E+      +  + VE   +   EK L   
Sbjct: 76  LSCE--CEAIKQQQKMHLEKLEEQLSRSHGQEVNELKTKIEKLKVELDEARLSEKQLKHQ 133

Query: 138 VDQTKD 143
           VD  K+
Sbjct: 134 VDHQKE 139


>gi|163659918 sacsin [Homo sapiens]
          Length = 4579

 Score = 28.5 bits (62), Expect = 4.7
 Identities = 21/60 (35%), Positives = 29/60 (48%), Gaps = 14/60 (23%)

Query: 122  VEEIISTEDEKILLESVDQ---TKDTDHQNFQKCLKHRRVKHFGY--------EFHCEKN 170
            V +  + ED  ++LES+DQ   TK    +NFQ C   RR+   G         +  CEKN
Sbjct: 2391 VRQSCTVEDFALVLESIDQERGTKQITEENFQLC---RRIISEGIWSLIREKKQEFCEKN 2447


>gi|54112394 calcium channel, voltage-dependent, alpha 2/delta
           subunit 2 isoform b [Homo sapiens]
          Length = 1143

 Score = 28.5 bits (62), Expect = 4.7
 Identities = 14/42 (33%), Positives = 24/42 (57%)

Query: 80  VTLNGKEIVDDLGQKMILYLNFVEKAQWKELGPQALPLVLIV 121
           + +N +E +D LG+ M+L     ++ QW  +   AL L L+V
Sbjct: 458 IRINTQEYLDVLGRPMVLAGKEAKQVQWTNVYEDALGLGLVV 499


>gi|54112392 calcium channel, voltage-dependent, alpha 2/delta
           subunit 2 isoform a [Homo sapiens]
          Length = 1145

 Score = 28.5 bits (62), Expect = 4.7
 Identities = 14/42 (33%), Positives = 24/42 (57%)

Query: 80  VTLNGKEIVDDLGQKMILYLNFVEKAQWKELGPQALPLVLIV 121
           + +N +E +D LG+ M+L     ++ QW  +   AL L L+V
Sbjct: 458 IRINTQEYLDVLGRPMVLAGKEAKQVQWTNVYEDALGLGLVV 499


>gi|221316689 cytidine triphosphate synthase II [Homo sapiens]
          Length = 586

 Score = 28.5 bits (62), Expect = 4.7
 Identities = 18/61 (29%), Positives = 31/61 (50%), Gaps = 2/61 (3%)

Query: 33 GLGNGVSRNQLLLVLEKCGL-VDALLMPPYKPYSFERYKTTEESKRAYVTLNGKEIVDDL 91
          G+G G+  + +  +L+ CGL V A+ + PY       +   E  +  +V  +G E+  DL
Sbjct: 13 GIGKGIIASSIGTILKSCGLRVTAIKIDPYINIDAGTFSPYEHGE-VFVLNDGGEVDLDL 71

Query: 92 G 92
          G
Sbjct: 72 G 72


>gi|28559085 cytidine triphosphate synthase II [Homo sapiens]
          Length = 586

 Score = 28.5 bits (62), Expect = 4.7
 Identities = 18/61 (29%), Positives = 31/61 (50%), Gaps = 2/61 (3%)

Query: 33 GLGNGVSRNQLLLVLEKCGL-VDALLMPPYKPYSFERYKTTEESKRAYVTLNGKEIVDDL 91
          G+G G+  + +  +L+ CGL V A+ + PY       +   E  +  +V  +G E+  DL
Sbjct: 13 GIGKGIIASSIGTILKSCGLRVTAIKIDPYINIDAGTFSPYEHGE-VFVLNDGGEVDLDL 71

Query: 92 G 92
          G
Sbjct: 72 G 72


>gi|28559083 cytidine triphosphate synthase II [Homo sapiens]
          Length = 586

 Score = 28.5 bits (62), Expect = 4.7
 Identities = 18/61 (29%), Positives = 31/61 (50%), Gaps = 2/61 (3%)

Query: 33 GLGNGVSRNQLLLVLEKCGL-VDALLMPPYKPYSFERYKTTEESKRAYVTLNGKEIVDDL 91
          G+G G+  + +  +L+ CGL V A+ + PY       +   E  +  +V  +G E+  DL
Sbjct: 13 GIGKGIIASSIGTILKSCGLRVTAIKIDPYINIDAGTFSPYEHGE-VFVLNDGGEVDLDL 71

Query: 92 G 92
          G
Sbjct: 72 G 72


>gi|194018497 FYVE, RhoGEF and PH domain containing 5 [Homo sapiens]
          Length = 1462

 Score = 28.5 bits (62), Expect = 4.7
 Identities = 22/64 (34%), Positives = 32/64 (50%), Gaps = 8/64 (12%)

Query: 4   AEAAGNEEKEEASKVILSAEEERLVVA--------SVGLGNGVSRNQLLLVLEKCGLVDA 55
           +E+A   E E+A K+ L AEE  +V A          G   G +   +++VLE+  L DA
Sbjct: 366 SESAKGLESEQAPKLGLRAEENPMVGALCGQCGSLQGGAAEGPAAPDVVVVLEEEALDDA 425

Query: 56  LLMP 59
           L  P
Sbjct: 426 LANP 429


>gi|54112390 calcium channel, voltage-dependent, alpha 2/delta
           subunit 1 [Homo sapiens]
          Length = 1091

 Score = 28.1 bits (61), Expect = 6.1
 Identities = 13/42 (30%), Positives = 25/42 (59%)

Query: 80  VTLNGKEIVDDLGQKMILYLNFVEKAQWKELGPQALPLVLIV 121
           + +N +E +D LG+ M+L  +  ++ QW  +   AL L L++
Sbjct: 419 IRINTQEYLDVLGRPMVLAGDKAKQVQWTNVYLDALELGLVI 460


>gi|50962882 G patch domain containing 8 [Homo sapiens]
          Length = 1502

 Score = 28.1 bits (61), Expect = 6.1
 Identities = 15/47 (31%), Positives = 25/47 (53%)

Query: 169 KNNVDKDKHLPRGLLDVCDSFLEKWLREGYIKHKPEQLTINQYEPGH 215
           K+ VDK+K + + L D+  +F  +   + Y KH+     IN Y+  H
Sbjct: 116 KDYVDKEKAIAKALEDLRANFYCELCDKQYQKHQEFDNHINSYDHAH 162


>gi|38569394 inhibitor of kappa light polypeptide gene enhancer in
           B-cells, kinase complex-associated protein [Homo
           sapiens]
          Length = 1332

 Score = 27.7 bits (60), Expect = 8.0
 Identities = 31/94 (32%), Positives = 47/94 (50%), Gaps = 11/94 (11%)

Query: 94  KMILYLNFVEKAQWKELGPQALPLVLIVVEEIISTEDEKILLESVDQTK--DTDHQNF-- 149
           K +L+L  V +     LG     LVL+V E+  S +D K  L  ++  K  +T++Q F  
Sbjct: 879 KYLLHLVDVNELYDHSLGTYDFDLVLMVAEK--SQKDPKEYLPFLNTLKKMETNYQRFTI 936

Query: 150 QKCLK--HRRVKHF---GYEFHCEKNNVDKDKHL 178
            K LK   + + H    G E+  E  N+ KDK+L
Sbjct: 937 DKYLKRYEKAIGHLSKCGPEYFPECLNLIKDKNL 970


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.136    0.399 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,788,399
Number of Sequences: 37866
Number of extensions: 382861
Number of successful extensions: 1013
Number of sequences better than 10.0: 21
Number of HSP's better than 10.0 without gapping: 14
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 997
Number of HSP's gapped (non-prelim): 23
length of query: 220
length of database: 18,247,518
effective HSP length: 98
effective length of query: 122
effective length of database: 14,536,650
effective search space: 1773471300
effective search space used: 1773471300
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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