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Search of human proteins with 16753231
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|16753231 tektin 1 [Homo sapiens]
(418 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|16753231 tektin 1 [Homo sapiens] 821 0.0
gi|13994250 tektin 3 [Homo sapiens] 286 2e-77
gi|21389613 tektin 4 [Homo sapiens] 277 1e-74
gi|21389569 tektin 5 [Homo sapiens] 260 1e-69
gi|239747088 PREDICTED: MAFF interacting protein [Homo sapiens] 235 5e-62
gi|16507950 tektin 2 [Homo sapiens] 211 1e-54
gi|239747014 PREDICTED: similar to tektin 4 [Homo sapiens] 167 1e-41
gi|75677606 hypothetical protein LOC100132288 [Homo sapiens] 81 2e-15
gi|239752581 PREDICTED: MAFF interacting protein [Homo sapiens] 64 2e-10
gi|239758055 PREDICTED: similar to tektin 4 [Homo sapiens] 63 6e-10
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 55 9e-08
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 55 9e-08
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 55 9e-08
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 55 9e-08
gi|45359873 OGT(O-Glc-NAc transferase)-interacting protein 106 K... 54 3e-07
gi|190341068 forkhead-associated (FHA) phosphopeptide binding do... 53 4e-07
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 52 8e-07
gi|221219020 NYD-SP11 protein [Homo sapiens] 52 1e-06
gi|111074532 OGT(O-Glc-NAc transferase)-interacting protein 106 ... 52 1e-06
gi|216548091 leucine zipper protein 1 [Homo sapiens] 51 2e-06
gi|216548085 leucine zipper protein 1 [Homo sapiens] 51 2e-06
gi|114155142 nuclear pore complex-associated protein TPR [Homo s... 51 2e-06
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa... 50 3e-06
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s... 50 3e-06
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 50 4e-06
gi|46049114 M-phase phosphoprotein 1 [Homo sapiens] 50 5e-06
gi|38044112 restin isoform b [Homo sapiens] 49 6e-06
gi|4506751 restin isoform a [Homo sapiens] 49 6e-06
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 49 8e-06
gi|56961680 coiled-coil domain containing 147 [Homo sapiens] 49 8e-06
>gi|16753231 tektin 1 [Homo sapiens]
Length = 418
Score = 821 bits (2121), Expect = 0.0
Identities = 418/418 (100%), Positives = 418/418 (100%)
Query: 1 MAKLLQPPPKFLPSEWHIANKNQYHRADAQRSRSERLVAESQRLVDEIEKTTRKSQSDVN 60
MAKLLQPPPKFLPSEWHIANKNQYHRADAQRSRSERLVAESQRLVDEIEKTTRKSQSDVN
Sbjct: 1 MAKLLQPPPKFLPSEWHIANKNQYHRADAQRSRSERLVAESQRLVDEIEKTTRKSQSDVN 60
Query: 61 KKLEQRLEEVQFWKKELDDKLEQLVNVTDDLLIYKIRLEKALETLKEPLHITETCLAYRE 120
KKLEQRLEEVQFWKKELDDKLEQLVNVTDDLLIYKIRLEKALETLKEPLHITETCLAYRE
Sbjct: 61 KKLEQRLEEVQFWKKELDDKLEQLVNVTDDLLIYKIRLEKALETLKEPLHITETCLAYRE 120
Query: 121 KRIGIDLVHDTVEHELIKEAEIIQGIMALLTRTLEEASEQIRMNRSAKYNLEKDLKDKFV 180
KRIGIDLVHDTVEHELIKEAEIIQGIMALLTRTLEEASEQIRMNRSAKYNLEKDLKDKFV
Sbjct: 121 KRIGIDLVHDTVEHELIKEAEIIQGIMALLTRTLEEASEQIRMNRSAKYNLEKDLKDKFV 180
Query: 181 ALTIDDICFSLNNNSPNIRYSENAVRIEPNSVSLEDWLDFSSTNVEKADKQRNNSLMLKA 240
ALTIDDICFSLNNNSPNIRYSENAVRIEPNSVSLEDWLDFSSTNVEKADKQRNNSLMLKA
Sbjct: 181 ALTIDDICFSLNNNSPNIRYSENAVRIEPNSVSLEDWLDFSSTNVEKADKQRNNSLMLKA 240
Query: 241 LVDRILSQTANDLRKQCDVVDTAFKNGLKDTKDARDKLADHLAKVMEEIASQEKNITALE 300
LVDRILSQTANDLRKQCDVVDTAFKNGLKDTKDARDKLADHLAKVMEEIASQEKNITALE
Sbjct: 241 LVDRILSQTANDLRKQCDVVDTAFKNGLKDTKDARDKLADHLAKVMEEIASQEKNITALE 300
Query: 301 KAILDQEGPAKVAHTRLETRTHRPNVELCRDVAQYRLMKEVQEITHNVARLKETLAQAQA 360
KAILDQEGPAKVAHTRLETRTHRPNVELCRDVAQYRLMKEVQEITHNVARLKETLAQAQA
Sbjct: 301 KAILDQEGPAKVAHTRLETRTHRPNVELCRDVAQYRLMKEVQEITHNVARLKETLAQAQA 360
Query: 361 ELKGLHRRQLALQEEIQVKENTIYIDEVLCMQMRKSIPLRDGEDHGVWAGGLRPDAVC 418
ELKGLHRRQLALQEEIQVKENTIYIDEVLCMQMRKSIPLRDGEDHGVWAGGLRPDAVC
Sbjct: 361 ELKGLHRRQLALQEEIQVKENTIYIDEVLCMQMRKSIPLRDGEDHGVWAGGLRPDAVC 418
>gi|13994250 tektin 3 [Homo sapiens]
Length = 490
Score = 286 bits (733), Expect = 2e-77
Identities = 145/389 (37%), Positives = 233/389 (59%)
Query: 10 KFLPSEWHIANKNQYHRADAQRSRSERLVAESQRLVDEIEKTTRKSQSDVNKKLEQRLEE 69
++ P +W+ +N Y ++ R SE+L ++ RL+ + + TRK+Q+D + L +R+ +
Sbjct: 93 RYTPDDWYRSNLTNYQESNTSRHNSEKLRVDTSRLIQDKYQQTRKTQADTTQNLGERVND 152
Query: 70 VQFWKKELDDKLEQLVNVTDDLLIYKIRLEKALETLKEPLHITETCLAYREKRIGIDLVH 129
+ FWK E+ +L++++ T+ L K RLE+AL + PL + CL +REKR+GIDLVH
Sbjct: 153 IGFWKSEIIHELDEMIGETNALTDVKKRLERALMETEAPLQVARECLFHREKRMGIDLVH 212
Query: 130 DTVEHELIKEAEIIQGIMALLTRTLEEASEQIRMNRSAKYNLEKDLKDKFVALTIDDICF 189
D VE +L+ E + I + L++A Q+ NR++++ LEKDL DK A IDD C
Sbjct: 213 DEVEAQLLTEVDTILCCQERMKLHLDKAIAQLAANRASQHELEKDLSDKQTAYRIDDKCH 272
Query: 190 SLNNNSPNIRYSENAVRIEPNSVSLEDWLDFSSTNVEKADKQRNNSLMLKALVDRILSQT 249
L N S + Y R++ E W F+ N+ ++ +R S L+ ++ +L T
Sbjct: 273 HLRNTSDGVGYFRGVERVDATVSVPESWAKFTDDNILRSQSERAASAKLRDDIENLLVVT 332
Query: 250 ANDLRKQCDVVDTAFKNGLKDTKDARDKLADHLAKVMEEIASQEKNITALEKAILDQEGP 309
AN++ Q + V+ +F N + +T DA++K+ HLAK ++EI E I +++KAI D+
Sbjct: 333 ANEMWNQFNKVNLSFTNRIAETADAKNKIQTHLAKTLQEIFQTEMTIESIKKAIKDKTAF 392
Query: 310 AKVAHTRLETRTHRPNVELCRDVAQYRLMKEVQEITHNVARLKETLAQAQAELKGLHRRQ 369
KVA TRL+ RT RPN+ELCRD+AQ RL+ EV E+ + L++ L A+ L+ L +
Sbjct: 393 LKVAQTRLDERTRRPNIELCRDMAQLRLVNEVHEVDDTIQTLQQRLRDAEDTLQSLVHIK 452
Query: 370 LALQEEIQVKENTIYIDEVLCMQMRKSIP 398
L+ ++ VK N++YID+ CM MRKS P
Sbjct: 453 ATLEYDLAVKANSLYIDQEKCMSMRKSYP 481
>gi|21389613 tektin 4 [Homo sapiens]
Length = 435
Score = 277 bits (708), Expect = 1e-74
Identities = 155/389 (39%), Positives = 229/389 (58%)
Query: 10 KFLPSEWHIANKNQYHRADAQRSRSERLVAESQRLVDEIEKTTRKSQSDVNKKLEQRLEE 69
K+L EW +YH+A A R +SER ESQ+L E + +++Q D + + +RL++
Sbjct: 38 KYLLEEWFQNCYARYHQAFADRDQSERQRHESQQLATETQALAQRTQQDSTRTVGERLQD 97
Query: 70 VQFWKKELDDKLEQLVNVTDDLLIYKIRLEKALETLKEPLHITETCLAYREKRIGIDLVH 129
WK EL ++E L T+ LL K RLE+AL+ + P IT L RE+R +LV
Sbjct: 98 THSWKSELQREMEALAAETNLLLAQKQRLERALDATEVPFSITTDNLQCRERREHPNLVR 157
Query: 130 DTVEHELIKEAEIIQGIMALLTRTLEEASEQIRMNRSAKYNLEKDLKDKFVALTIDDICF 189
D VE EL+KEAE+I+ I LL RT+ +A QIR+NR K E D DK A ID+ C
Sbjct: 158 DHVETELLKEAELIRNIQELLKRTIMQAVSQIRLNREHKETCEMDWSDKMEAYNIDETCG 217
Query: 190 SLNNNSPNIRYSENAVRIEPNSVSLEDWLDFSSTNVEKADKQRNNSLMLKALVDRILSQT 249
++ S ++ + + ++ + E F+ N+ +A ++R S L+ LVD IL T
Sbjct: 218 RHHSQSTEVQAHPYSTTFQESASTPETRAKFTQDNLCRAQRERLASANLRVLVDCILRDT 277
Query: 250 ANDLRKQCDVVDTAFKNGLKDTKDARDKLADHLAKVMEEIASQEKNITALEKAILDQEGP 309
+ DLR QCD V+ AF ++ +DAR KL HL K + EI QE N+ AL++AI D+E P
Sbjct: 278 SEDLRLQCDAVNLAFGRRCEELEDARYKLHHHLHKTLREITDQEHNVAALKQAIKDKEAP 337
Query: 310 AKVAHTRLETRTHRPNVELCRDVAQYRLMKEVQEITHNVARLKETLAQAQAELKGLHRRQ 369
VA TRL R+HRPN+ELCRD AQ+RL+ EV+E+ ++ L+E L +A+ L+ L
Sbjct: 338 LHVAQTRLYLRSHRPNMELCRDAAQFRLLSEVEELNMSLTALREKLLEAEQSLRNLEDIH 397
Query: 370 LALQEEIQVKENTIYIDEVLCMQMRKSIP 398
++L+++I N+++ID CM R P
Sbjct: 398 MSLEKDIAAMTNSLFIDRQKCMAHRTRYP 426
>gi|21389569 tektin 5 [Homo sapiens]
Length = 485
Score = 260 bits (665), Expect = 1e-69
Identities = 142/389 (36%), Positives = 221/389 (56%)
Query: 10 KFLPSEWHIANKNQYHRADAQRSRSERLVAESQRLVDEIEKTTRKSQSDVNKKLEQRLEE 69
++ P +W +N+ Q A+A R + RL +S RL+ + ++ T + Q + L QRL +
Sbjct: 88 RYSPHDWDQSNQLQVRGAEASRLWASRLTDDSMRLLQDKDQLTHQMQEGTCRNLGQRLSD 147
Query: 70 VQFWKKELDDKLEQLVNVTDDLLIYKIRLEKALETLKEPLHITETCLAYREKRIGIDLVH 129
+ FWK EL +L++L+ +L K RLE A + PL + CL +REKRIGIDLVH
Sbjct: 148 IGFWKSELSYELDRLLTENQNLETVKRRLECAANEVNCPLQVALECLYHREKRIGIDLVH 207
Query: 130 DTVEHELIKEAEIIQGIMALLTRTLEEASEQIRMNRSAKYNLEKDLKDKFVALTIDDICF 189
D VE LI+E ++++ + + + Q+R NR A++ LE+DL+DK A ID+ CF
Sbjct: 208 DNVEKNLIREVDLLKCCQEQMRKLAQRIDIQMRDNRDAQHVLERDLEDKSSAQCIDEKCF 267
Query: 190 SLNNNSPNIRYSENAVRIEPNSVSLEDWLDFSSTNVEKADKQRNNSLMLKALVDRILSQT 249
+L N S I + +I+ E W FS+ N++ + R NS+ L+ + +
Sbjct: 268 NLRNTSDCISFFHGMEKIDGTISVPETWAKFSNDNIKHSQNMRANSIQLREEAEHLFETL 327
Query: 250 ANDLRKQCDVVDTAFKNGLKDTKDARDKLADHLAKVMEEIASQEKNITALEKAILDQEGP 309
++ + +Q + AF + + D ++KL LAK ++EI E I LE++I+ +EGP
Sbjct: 328 SDQMWRQFTDTNLAFNARISEVTDVKNKLQTQLAKTLQEIFQAENTIMLLERSIMAKEGP 387
Query: 310 AKVAHTRLETRTHRPNVELCRDVAQYRLMKEVQEITHNVARLKETLAQAQAELKGLHRRQ 369
KVA TRLE RT RPN+ELCRD+ Q +L+ EV I + LK L + Q L+ L +
Sbjct: 388 LKVAQTRLECRTRRPNMELCRDIPQLKLVNEVFTIDDTLQTLKLRLRETQDTLQLLVMTK 447
Query: 370 LALQEEIQVKENTIYIDEVLCMQMRKSIP 398
L+ E+ +K NT+ ID+ CM MRK+ P
Sbjct: 448 CRLEHELAIKANTLCIDKEKCMGMRKTFP 476
>gi|239747088 PREDICTED: MAFF interacting protein [Homo sapiens]
Length = 445
Score = 235 bits (600), Expect = 5e-62
Identities = 139/382 (36%), Positives = 216/382 (56%), Gaps = 6/382 (1%)
Query: 23 QYHRADAQRSRSERLVA--ESQRLVDEIEKTTRKSQSDVNKKLEQRLEEVQFWKKELDDK 80
+Y +A A ++SER + ESQ+L E + + +Q D ++ +RL++ WK EL +
Sbjct: 55 RYRQAFANCNQSERELQGHESQQLAAETQALAQPTQQDSTCRVGERLQDTNSWKSELQRE 114
Query: 81 LEQLVNVTDDLLIYKIRLEKALETLKEPLHITETCLAYREKRIGIDLVHDTVEHELIKEA 140
+E L TD LL K RLE+AL+ ++ P IT + ++ +L+ D VE EL+KEA
Sbjct: 115 VEALAAETDLLLAQKQRLERALDAMEVPFSITTDNMQCSQRHQHTNLLRDHVETELLKEA 174
Query: 141 EIIQGIMALLTRTLEEASEQIRMNRSAKYNLEKDLKDKFVALTIDDICFSLNNNSPNIRY 200
E+I+ I LL R + +A QI +N E D DK A +D C ++ S ++
Sbjct: 175 ELIRNIQELLKRAIMQAVSQIXLNXEHMEICEMDWSDKVEAYNLDKTCGRHHSQSTEVQA 234
Query: 201 SENAVRIE---PNSVSL-EDWLDFSSTNVEKADKQRNNSLMLKALVDRILSQTANDLRKQ 256
++ + P S S E F+ N+ A ++R +S L LVD IL T+ DL Q
Sbjct: 235 HPHSTTFQERGPRSASTPETRTKFTQDNLCHAQRERLDSANLWVLVDCILRDTSEDLGLQ 294
Query: 257 CDVVDTAFKNGLKDTKDARDKLADHLAKVMEEIASQEKNITALEKAILDQEGPAKVAHTR 316
CD V+ AF ++ +DAR KL HL K++ EI QE N+ AL++AI D+E P +A TR
Sbjct: 295 CDAVNLAFGRRCEELEDARHKLQHHLHKMLREITDQEHNVVALKEAIKDKEEPLHIAQTR 354
Query: 317 LETRTHRPNVELCRDVAQYRLMKEVQEITHNVARLKETLAQAQAELKGLHRRQLALQEEI 376
L +HRPN++LCRD AQ+RL+ EV+E+ ++ L+E L QA+ L+ L ++L++++
Sbjct: 355 LXLLSHRPNMQLCRDAAQFRLVSEVEELYKSITALREKLLQAEQSLRNLKDIHMSLEKDV 414
Query: 377 QVKENTIYIDEVLCMQMRKSIP 398
N+++ID CM R P
Sbjct: 415 TAMTNSVFIDRQKCMAHRTCYP 436
>gi|16507950 tektin 2 [Homo sapiens]
Length = 430
Score = 211 bits (536), Expect = 1e-54
Identities = 131/393 (33%), Positives = 202/393 (51%), Gaps = 1/393 (0%)
Query: 5 LQPPPKFLPSEWHIANKNQYHRADAQRSRSERLVAESQRLVDEIEKTTRKSQSDVNKKLE 64
++P +F +WH + A QR S ++ E++ L +E T + D +L
Sbjct: 6 VKPSRRFQLPDWHTNSYLLSTNAQLQRDASHQIRQEARVLRNETNNQTIWDEHDNRTRLV 65
Query: 65 QRLEEVQFWKKELDDKLEQLVNVTDDLLIYKIRLEKALETLKEPLHITETCLAYREKRIG 124
+R++ V WK+ LD L L D L K E+ L+ PL + CL RE R
Sbjct: 66 ERIDTVNRWKEMLDKCLTDLDAEIDALTQMKESAEQNLQAKNLPLDVAIECLTLRESRRD 125
Query: 125 IDLVHDTVEHELIKEAEIIQGIMALLTRTLEEASEQIRMNRSAKYNLEKDLKDKFVALTI 184
ID+V D VE EL KE E+I+ L + + +A EQ+ + + + L D + K L I
Sbjct: 126 IDVVKDPVEDELHKEVEVIEATKKALQQKVSQAFEQLCLLQEVQQQLNSDHRGKMETLEI 185
Query: 185 DDICFSLNNNSPNIRYSENAVRIEPNSVSLEDWLDFSSTNVEKADKQRNNSLMLKALVDR 244
D C SLN SPNI + R+ S +L+ W DFS N ++A+ + + L+
Sbjct: 186 DRGCLSLNLRSPNISLKVDPTRVPDGSTTLQQWDDFSRFNKDRAEAEMKAATELREATAL 245
Query: 245 ILSQTANDLRKQCDVVDTAFKNGLKDTKDARDKLADHLAKVMEEIASQEKNITALEKAIL 304
+++T N+L Q + AF+ L++ + +L +EEIA +++I LE+ +
Sbjct: 246 TIAETNNELEAQRVATEFAFRKRLREMEKVYSELKWQEKNTLEEIAELQEDIRHLEEDLR 305
Query: 305 DQEGPAKVAHTRLETRTHRPNVELCRDVAQYRLMKEVQEITHNVARLKETLAQAQAELKG 364
+ K++HTRLE RT+RPNVELCRD AQY L EV ++ +A LK+ LAQAQ L
Sbjct: 306 TKLLSLKLSHTRLEARTYRPNVELCRDQAQYGLTDEVHQLEATIAALKQKLAQAQDALDA 365
Query: 365 LHRRQLALQEEIQVKENTIYIDEVLCMQMRKSI 397
L + LQ +I K N++ +D CM R+ +
Sbjct: 366 LCKHLARLQADIACKANSMLLD-TKCMDTRRKL 397
>gi|239747014 PREDICTED: similar to tektin 4 [Homo sapiens]
Length = 507
Score = 167 bits (424), Expect = 1e-41
Identities = 139/502 (27%), Positives = 210/502 (41%), Gaps = 118/502 (23%)
Query: 4 LLQPPPKFLPSEWHIANKNQYHRADAQRSRSERLVAESQRLVDEIEKTTRKSQSDVNKKL 63
L +P P+ +P + AD +S E +SQ+L EI+ + +Q D ++
Sbjct: 8 LPEPAPQTVPPCELPCKEYDVAFADCNQSERELQGHKSQQLAAEIQALAQPTQQDSKCRV 67
Query: 64 EQRLEEVQFWKKELDDKLEQLVNVTDDLLIYKIRLEKAL--------------------- 102
+RL+++ W EL ++E L TD LL K RLE AL
Sbjct: 68 GERLQDMHSWNSELQGEVEALAAETDLLLAQKQRLEHALDAMEVPFSIATDNMQCNQRHQ 127
Query: 103 -----------ETLKE----PLHITETCLAYREKRIGIDLVHDTVEHELIKE-------- 139
E LK P + C + R+ V + +E ++E
Sbjct: 128 HANLVRDHVETELLKAYPPAPSQCLKNCCSSRKPSASNKGVCEVMETLTVQEEANPGTEG 187
Query: 140 -----------AEIIQGIMALLTRTLEEASEQIRMNRSAKYNLEKDLKDKFVALTIDDIC 188
AE+I+ I LL R + +A QIR+NR E D DK A +D+ C
Sbjct: 188 CRTRALAHKEEAELIRNIQELLKRVIVQAVSQIRLNREHMEICEMDWSDKVEAYNLDETC 247
Query: 189 FSLNNNSPNIRYSENAVRIEPNSVSL-EDWLDFSSTNVEKADKQRNNSLMLKALVDRILS 247
+ S EP S S E F+ N+ +A ++R +S L LVD IL
Sbjct: 248 GRHRSQST-----------EPRSASTPETRTKFTQDNLCRAQRERLDSANLWVLVDCILR 296
Query: 248 QTANDLRKQCDVVDTAFKNGLKDTKDARDKLADHLAKVMEEIASQEKNITALEKAILDQE 307
T+ DL QCD V+ AF ++ +DAR KL HL K++ EI QE N+ AL++AI D+E
Sbjct: 297 DTSEDLGLQCDAVNLAFGRRCEELEDARHKLQHHLQKMLREITDQEHNMVALKEAIKDKE 356
Query: 308 GPAKVAHTRLETRTHRPNVELCRDVAQYR------------------------------- 336
P +A TRL +HRPN+ELCRD AQ+R
Sbjct: 357 APLHIAQTRLYLLSHRPNMELCRDAAQFRYRHDTGQVMGRGPPSARDLCPRGLTPPSATS 416
Query: 337 --------------------LMKEVQEITHNVARLKETLAQAQAELKGLHRRQLALQEEI 376
L+ E++E+ ++ L E L QA+ L L ++L++++
Sbjct: 417 SSQEEAPSDKPQLTPPNTPKLVSELEELYKSITALWEKLLQAEQSLHNLEDIHMSLEKDV 476
Query: 377 QVKENTIYIDEVLCMQMRKSIP 398
N++++D CM P
Sbjct: 477 TAMTNSLFLDRQNCMAHHTCYP 498
>gi|75677606 hypothetical protein LOC100132288 [Homo sapiens]
Length = 129
Score = 81.3 bits (199), Expect = 2e-15
Identities = 48/110 (43%), Positives = 65/110 (59%), Gaps = 1/110 (0%)
Query: 209 PNSVSL-EDWLDFSSTNVEKADKQRNNSLMLKALVDRILSQTANDLRKQCDVVDTAFKNG 267
P S S E F+ N+ A ++R +S L LVD IL T+ DL QCD V+ AF
Sbjct: 20 PRSASTPETRTKFTQDNLCHAQRERLDSANLWVLVDCILRDTSEDLGLQCDAVNLAFGCR 79
Query: 268 LKDTKDARDKLADHLAKVMEEIASQEKNITALEKAILDQEGPAKVAHTRL 317
++ +DAR KL HL K++ EI QE N+ AL++AI D+E P +A TRL
Sbjct: 80 CEELEDARHKLQHHLHKMLREITDQEHNVVALKEAIKDKEEPLHIAQTRL 129
Score = 30.4 bits (67), Expect = 3.1
Identities = 29/92 (31%), Positives = 46/92 (50%), Gaps = 6/92 (6%)
Query: 29 AQRSRSERLVAESQRLVDEIEKTTRKS---QSD-VNKKLEQRLEEVQFWKKELDDKLEQL 84
AQR R + A LVD I + T + Q D VN R EE++ + +L L ++
Sbjct: 40 AQRERLDS--ANLWVLVDCILRDTSEDLGLQCDAVNLAFGCRCEELEDARHKLQHHLHKM 97
Query: 85 VNVTDDLLIYKIRLEKALETLKEPLHITETCL 116
+ D + L++A++ +EPLHI +T L
Sbjct: 98 LREITDQEHNVVALKEAIKDKEEPLHIAQTRL 129
>gi|239752581 PREDICTED: MAFF interacting protein [Homo sapiens]
Length = 333
Score = 64.3 bits (155), Expect = 2e-10
Identities = 40/118 (33%), Positives = 65/118 (55%), Gaps = 2/118 (1%)
Query: 23 QYHRADAQRSRSERLVA--ESQRLVDEIEKTTRKSQSDVNKKLEQRLEEVQFWKKELDDK 80
+YH+A A ++SE+ + ESQ+L E + + +Q D +++ ++L++ WK EL +
Sbjct: 40 RYHQAFANCNQSEQELQGHESQQLAAETQALAQGTQQDSTRRVGEQLQDTHSWKSELQRE 99
Query: 81 LEQLVNVTDDLLIYKIRLEKALETLKEPLHITETCLAYREKRIGIDLVHDTVEHELIK 138
+E L TD LL K RLE AL+ + P I L + +L+ D VE EL+K
Sbjct: 100 VEALAAETDLLLAQKQRLEHALDATEAPFSIATDNLQCSQGHQHANLMRDHVETELLK 157
Score = 45.4 bits (106), Expect = 9e-05
Identities = 30/95 (31%), Positives = 45/95 (47%), Gaps = 3/95 (3%)
Query: 106 KEPLHITETCLAYREKRIGIDLVHD-TVEHELIKEAEIIQGIMALLTRTLEEASEQIRMN 164
K P + ET E G + + H+ KEAE+I+ I LL R + +A QIR+N
Sbjct: 181 KGPCQVMETLTVQEEANPGTEGCRTRALAHK--KEAELIRNIQELLKRAIVQAVSQIRLN 238
Query: 165 RSAKYNLEKDLKDKFVALTIDDICFSLNNNSPNIR 199
R E D DK A +D+ C ++ S ++
Sbjct: 239 REHTEICEMDWSDKVEAYNLDETCGRHHSQSTEVQ 273
>gi|239758055 PREDICTED: similar to tektin 4 [Homo sapiens]
Length = 254
Score = 62.8 bits (151), Expect = 6e-10
Identities = 46/140 (32%), Positives = 70/140 (50%), Gaps = 10/140 (7%)
Query: 8 PPKFLPSEWH--IANKNQYHRADAQRSRSERLVAESQRLVDEIEKTTRKSQSDVNKKLEQ 65
PP LP + + AN NQ R + Q S++L AE+Q L + +Q D +++ +
Sbjct: 17 PPCELPCKEYDAFANCNQSER-ELQGHESQQLAAETQALA-------QGTQQDSTRRVGE 68
Query: 66 RLEEVQFWKKELDDKLEQLVNVTDDLLIYKIRLEKALETLKEPLHITETCLAYREKRIGI 125
+L++ WK EL ++E L TD LL K RLE AL+ + P I L +
Sbjct: 69 QLQDTHSWKSELQREVEALAAETDLLLAQKQRLEHALDATEAPFSIATDNLQCSQGHQNA 128
Query: 126 DLVHDTVEHELIKEAEIIQG 145
+L+ D VE EL+K + G
Sbjct: 129 NLMRDHVETELLKVPAAVGG 148
Score = 28.9 bits (63), Expect = 9.1
Identities = 20/58 (34%), Positives = 28/58 (48%), Gaps = 3/58 (5%)
Query: 106 KEPLHITETCLAYREKRIGIDLVHD-TVEHELIKEAEIIQGIMALLTRTLEEASEQIR 162
K P + ET E G + + H+ KEAE+I+ I LL R + +A QIR
Sbjct: 189 KGPCQVMETLTVQEEANPGTEGCRTRALAHK--KEAELIRNIQELLKRAIVQAVSQIR 244
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 55.5 bits (132), Expect = 9e-08
Identities = 67/342 (19%), Positives = 141/342 (41%), Gaps = 49/342 (14%)
Query: 40 ESQRLVDEIEKTTRKSQSDVN--KKLEQRLEEVQFWKKELDDKLEQLVNVTDDLLIYKIR 97
E Q DE++KT + Q N K+LEQ+ ++ K L ++L+ + + ++R
Sbjct: 853 EMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVR 912
Query: 98 LEKALETLKEPLHITETCLAYREKRIGIDLVHDTVEHELIKEAEIIQGIMALLTRTLEEA 157
L + L+E LH E L E R + +Q + + + +
Sbjct: 913 LAAKKQELEEILHEMEARLEEEEDR-----------------GQQLQAERKKMAQQMLDL 955
Query: 158 SEQIRMNRSA--KYNLEKDLKDKFVALTIDDICFSLNNNSPNIRYSENAVRIEPNSVSLE 215
EQ+ +A K LEK + + D+I + N+ ++ LE
Sbjct: 956 EEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNN----------KLSKERKLLE 1005
Query: 216 DWLDFSSTNVEKADKQRNNSLMLKALVDRILSQTANDLRKQCDVVDTAFKNGLKDTKDAR 275
+ + +TN+ + +++ N LK + ++S+ L+K+ + ++ + +
Sbjct: 1006 ERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKE--------EKSRQELEKLK 1057
Query: 276 DKLADHLAKVMEEIASQEKNITALEKAILDQEGPAKVAHTRLETRTHRPNVELCRDVAQY 335
KL + E+IA + I L+ + +E + A RL+ + N
Sbjct: 1058 RKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKN---------- 1107
Query: 336 RLMKEVQEITHNVARLKETLAQAQAELKGLHRRQLALQEEIQ 377
+K+++E+ +++ L+E L +A +++ L EE++
Sbjct: 1108 NALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELE 1149
Score = 44.3 bits (103), Expect = 2e-04
Identities = 83/403 (20%), Positives = 163/403 (40%), Gaps = 70/403 (17%)
Query: 26 RADAQRSRSERLVAESQRLVDEIEKTTRKSQSDVNKKLEQRLE-EVQFWKKELDDKLEQL 84
R A++ E ++ E + ++E E ++ Q++ K +Q L+ E Q ++E + QL
Sbjct: 912 RLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQL 971
Query: 85 VNVTDDLLIYKI------------RLEKALETLKEPLHITETCLAYREKRIGIDLVHDTV 132
VT + I K+ +L K + L+E + T LA E++ +L
Sbjct: 972 EKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAK-NLTKLKN 1030
Query: 133 EHE-LIKEAEIIQGIMALLTRTLEEASEQIRMNRSAKYNLEKDLKDKFVALTI------D 185
+HE +I E E+ + LE+ ++ + S + DL+ + L + +
Sbjct: 1031 KHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEE 1090
Query: 186 DICFSLNNNSPNIRYSENAVR----IEPNSVSLEDWLDFSSTNVEKADKQRNNS----LM 237
++ +L I NA++ +E + L++ LD KA+KQ+ +
Sbjct: 1091 ELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEA 1150
Query: 238 LKALVDRILSQTAN--DLRKQCDVVDTAFKNGLKD--------TKDARDKLADHLAKVME 287
LK ++ L TA +LR + + T K L + ++ R K A + ++ E
Sbjct: 1151 LKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTE 1210
Query: 288 EI-------ASQEKNITALEKAILDQEGPAKVAHTRLETRTHRPNVELCRDVAQYRLMKE 340
++ A+ +KN LEK D G +V L +
Sbjct: 1211 QLEQFKRAKANLDKNKQTLEKENADLAGELRV------------------------LGQA 1246
Query: 341 VQEITHNVARLKETLAQAQAELKGLHRRQLALQEEIQVKENTI 383
QE+ H +L+ + + Q++ R + L +++ +N +
Sbjct: 1247 KQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEV 1289
Score = 43.1 bits (100), Expect = 5e-04
Identities = 74/367 (20%), Positives = 138/367 (37%), Gaps = 58/367 (15%)
Query: 42 QRLVDEIEKTTRK------SQSDVNKKLEQRLEEVQFWKKELDDKLEQLVNVTDDLLIYK 95
++LV +EK RK + +++ K + + +E + K L ++ L K
Sbjct: 1440 RQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAK 1499
Query: 96 IRLEKALETLKEPLHITETCLAYREKRIGIDLVHDTVEHELIKEAEIIQGIMALLTRTLE 155
LE+ + LK + L + +G ++ HEL K ++ M + LE
Sbjct: 1500 EELERTNKMLKAEMED----LVSSKDDVGKNV------HELEKSKRALETQMEEMKTQLE 1549
Query: 156 EASEQIRMNRSAKYNLE---KDLKDKFVALTIDDICFSLNNNSPNIRYSENAVRIEPNSV 212
E ++++ AK LE + LK +F R +N E
Sbjct: 1550 ELEDELQATEDAKLRLEVNMQALKGQF-------------ERDLQARDEQN----EEKRR 1592
Query: 213 SLEDWLDFSSTNVEKADKQRNNSLMLKALVDRILSQTANDLRKQCDVVDTAFKNGLKDTK 272
L+ L T +E KQR L A + L DL Q D + +K +
Sbjct: 1593 QLQRQLHEYETELEDERKQR----ALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLR 1648
Query: 273 DARDKLADHLAKVMEEIASQ----------EKNITALEKAILD-QEGPAKVAHTRLETRT 321
+ ++ D ++ + AS+ EK +LE ++ QE A R +
Sbjct: 1649 KLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADL 1708
Query: 322 HRPNVELCRDVA-----QYRLMKEVQEITHNVARLKETLAQAQAELKGLHRRQLALQEEI 376
+ EL ++A + L E + + +A+L+E L + Q ++ + R ++
Sbjct: 1709 EKE--ELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQA 1766
Query: 377 QVKENTI 383
+ N +
Sbjct: 1767 EQLSNEL 1773
Score = 30.4 bits (67), Expect = 3.1
Identities = 33/122 (27%), Positives = 60/122 (49%), Gaps = 18/122 (14%)
Query: 263 AFKNGLKDTKDARDKLADHLAKVMEEIASQEKNITALEKAILDQEGPAKVAHTRLETRTH 322
A ++ L+ TK+ + K + L +E+ + +T EK +L ++ A+ T L
Sbjct: 856 AKEDELQKTKERQQKAENEL----KELEQKHSQLTE-EKNLLQEQLQAE---TELYAEAE 907
Query: 323 RPNVELCRDVAQYRLMKEVQEITHNV-ARLKETL---AQAQAELKGLHRRQLALQEEIQV 378
V L +E++EI H + ARL+E Q QAE K + ++ L L+E+++
Sbjct: 908 EMRVRLAAK------KQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEE 961
Query: 379 KE 380
+E
Sbjct: 962 EE 963
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 55.5 bits (132), Expect = 9e-08
Identities = 67/342 (19%), Positives = 141/342 (41%), Gaps = 49/342 (14%)
Query: 40 ESQRLVDEIEKTTRKSQSDVN--KKLEQRLEEVQFWKKELDDKLEQLVNVTDDLLIYKIR 97
E Q DE++KT + Q N K+LEQ+ ++ K L ++L+ + + ++R
Sbjct: 860 EMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVR 919
Query: 98 LEKALETLKEPLHITETCLAYREKRIGIDLVHDTVEHELIKEAEIIQGIMALLTRTLEEA 157
L + L+E LH E L E R + +Q + + + +
Sbjct: 920 LAAKKQELEEILHEMEARLEEEEDR-----------------GQQLQAERKKMAQQMLDL 962
Query: 158 SEQIRMNRSA--KYNLEKDLKDKFVALTIDDICFSLNNNSPNIRYSENAVRIEPNSVSLE 215
EQ+ +A K LEK + + D+I + N+ ++ LE
Sbjct: 963 EEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNN----------KLSKERKLLE 1012
Query: 216 DWLDFSSTNVEKADKQRNNSLMLKALVDRILSQTANDLRKQCDVVDTAFKNGLKDTKDAR 275
+ + +TN+ + +++ N LK + ++S+ L+K+ + ++ + +
Sbjct: 1013 ERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKE--------EKSRQELEKLK 1064
Query: 276 DKLADHLAKVMEEIASQEKNITALEKAILDQEGPAKVAHTRLETRTHRPNVELCRDVAQY 335
KL + E+IA + I L+ + +E + A RL+ + N
Sbjct: 1065 RKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKN---------- 1114
Query: 336 RLMKEVQEITHNVARLKETLAQAQAELKGLHRRQLALQEEIQ 377
+K+++E+ +++ L+E L +A +++ L EE++
Sbjct: 1115 NALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELE 1156
Score = 44.3 bits (103), Expect = 2e-04
Identities = 83/403 (20%), Positives = 163/403 (40%), Gaps = 70/403 (17%)
Query: 26 RADAQRSRSERLVAESQRLVDEIEKTTRKSQSDVNKKLEQRLE-EVQFWKKELDDKLEQL 84
R A++ E ++ E + ++E E ++ Q++ K +Q L+ E Q ++E + QL
Sbjct: 919 RLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQL 978
Query: 85 VNVTDDLLIYKI------------RLEKALETLKEPLHITETCLAYREKRIGIDLVHDTV 132
VT + I K+ +L K + L+E + T LA E++ +L
Sbjct: 979 EKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAK-NLTKLKN 1037
Query: 133 EHE-LIKEAEIIQGIMALLTRTLEEASEQIRMNRSAKYNLEKDLKDKFVALTI------D 185
+HE +I E E+ + LE+ ++ + S + DL+ + L + +
Sbjct: 1038 KHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEE 1097
Query: 186 DICFSLNNNSPNIRYSENAVR----IEPNSVSLEDWLDFSSTNVEKADKQRNNS----LM 237
++ +L I NA++ +E + L++ LD KA+KQ+ +
Sbjct: 1098 ELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEA 1157
Query: 238 LKALVDRILSQTAN--DLRKQCDVVDTAFKNGLKD--------TKDARDKLADHLAKVME 287
LK ++ L TA +LR + + T K L + ++ R K A + ++ E
Sbjct: 1158 LKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTE 1217
Query: 288 EI-------ASQEKNITALEKAILDQEGPAKVAHTRLETRTHRPNVELCRDVAQYRLMKE 340
++ A+ +KN LEK D G +V L +
Sbjct: 1218 QLEQFKRAKANLDKNKQTLEKENADLAGELRV------------------------LGQA 1253
Query: 341 VQEITHNVARLKETLAQAQAELKGLHRRQLALQEEIQVKENTI 383
QE+ H +L+ + + Q++ R + L +++ +N +
Sbjct: 1254 KQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEV 1296
Score = 43.1 bits (100), Expect = 5e-04
Identities = 74/367 (20%), Positives = 138/367 (37%), Gaps = 58/367 (15%)
Query: 42 QRLVDEIEKTTRK------SQSDVNKKLEQRLEEVQFWKKELDDKLEQLVNVTDDLLIYK 95
++LV +EK RK + +++ K + + +E + K L ++ L K
Sbjct: 1447 RQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAK 1506
Query: 96 IRLEKALETLKEPLHITETCLAYREKRIGIDLVHDTVEHELIKEAEIIQGIMALLTRTLE 155
LE+ + LK + L + +G ++ HEL K ++ M + LE
Sbjct: 1507 EELERTNKMLKAEMED----LVSSKDDVGKNV------HELEKSKRALETQMEEMKTQLE 1556
Query: 156 EASEQIRMNRSAKYNLE---KDLKDKFVALTIDDICFSLNNNSPNIRYSENAVRIEPNSV 212
E ++++ AK LE + LK +F R +N E
Sbjct: 1557 ELEDELQATEDAKLRLEVNMQALKGQF-------------ERDLQARDEQN----EEKRR 1599
Query: 213 SLEDWLDFSSTNVEKADKQRNNSLMLKALVDRILSQTANDLRKQCDVVDTAFKNGLKDTK 272
L+ L T +E KQR L A + L DL Q D + +K +
Sbjct: 1600 QLQRQLHEYETELEDERKQR----ALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLR 1655
Query: 273 DARDKLADHLAKVMEEIASQ----------EKNITALEKAILD-QEGPAKVAHTRLETRT 321
+ ++ D ++ + AS+ EK +LE ++ QE A R +
Sbjct: 1656 KLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADL 1715
Query: 322 HRPNVELCRDVA-----QYRLMKEVQEITHNVARLKETLAQAQAELKGLHRRQLALQEEI 376
+ EL ++A + L E + + +A+L+E L + Q ++ + R ++
Sbjct: 1716 EKE--ELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQA 1773
Query: 377 QVKENTI 383
+ N +
Sbjct: 1774 EQLSNEL 1780
Score = 30.4 bits (67), Expect = 3.1
Identities = 33/122 (27%), Positives = 60/122 (49%), Gaps = 18/122 (14%)
Query: 263 AFKNGLKDTKDARDKLADHLAKVMEEIASQEKNITALEKAILDQEGPAKVAHTRLETRTH 322
A ++ L+ TK+ + K + L +E+ + +T EK +L ++ A+ T L
Sbjct: 863 AKEDELQKTKERQQKAENEL----KELEQKHSQLTE-EKNLLQEQLQAE---TELYAEAE 914
Query: 323 RPNVELCRDVAQYRLMKEVQEITHNV-ARLKETL---AQAQAELKGLHRRQLALQEEIQV 378
V L +E++EI H + ARL+E Q QAE K + ++ L L+E+++
Sbjct: 915 EMRVRLAAK------KQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEE 968
Query: 379 KE 380
+E
Sbjct: 969 EE 970
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 55.5 bits (132), Expect = 9e-08
Identities = 67/342 (19%), Positives = 141/342 (41%), Gaps = 49/342 (14%)
Query: 40 ESQRLVDEIEKTTRKSQSDVN--KKLEQRLEEVQFWKKELDDKLEQLVNVTDDLLIYKIR 97
E Q DE++KT + Q N K+LEQ+ ++ K L ++L+ + + ++R
Sbjct: 860 EMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVR 919
Query: 98 LEKALETLKEPLHITETCLAYREKRIGIDLVHDTVEHELIKEAEIIQGIMALLTRTLEEA 157
L + L+E LH E L E R + +Q + + + +
Sbjct: 920 LAAKKQELEEILHEMEARLEEEEDR-----------------GQQLQAERKKMAQQMLDL 962
Query: 158 SEQIRMNRSA--KYNLEKDLKDKFVALTIDDICFSLNNNSPNIRYSENAVRIEPNSVSLE 215
EQ+ +A K LEK + + D+I + N+ ++ LE
Sbjct: 963 EEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNN----------KLSKERKLLE 1012
Query: 216 DWLDFSSTNVEKADKQRNNSLMLKALVDRILSQTANDLRKQCDVVDTAFKNGLKDTKDAR 275
+ + +TN+ + +++ N LK + ++S+ L+K+ + ++ + +
Sbjct: 1013 ERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKE--------EKSRQELEKLK 1064
Query: 276 DKLADHLAKVMEEIASQEKNITALEKAILDQEGPAKVAHTRLETRTHRPNVELCRDVAQY 335
KL + E+IA + I L+ + +E + A RL+ + N
Sbjct: 1065 RKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKN---------- 1114
Query: 336 RLMKEVQEITHNVARLKETLAQAQAELKGLHRRQLALQEEIQ 377
+K+++E+ +++ L+E L +A +++ L EE++
Sbjct: 1115 NALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELE 1156
Score = 44.3 bits (103), Expect = 2e-04
Identities = 83/403 (20%), Positives = 163/403 (40%), Gaps = 70/403 (17%)
Query: 26 RADAQRSRSERLVAESQRLVDEIEKTTRKSQSDVNKKLEQRLE-EVQFWKKELDDKLEQL 84
R A++ E ++ E + ++E E ++ Q++ K +Q L+ E Q ++E + QL
Sbjct: 919 RLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQL 978
Query: 85 VNVTDDLLIYKI------------RLEKALETLKEPLHITETCLAYREKRIGIDLVHDTV 132
VT + I K+ +L K + L+E + T LA E++ +L
Sbjct: 979 EKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAK-NLTKLKN 1037
Query: 133 EHE-LIKEAEIIQGIMALLTRTLEEASEQIRMNRSAKYNLEKDLKDKFVALTI------D 185
+HE +I E E+ + LE+ ++ + S + DL+ + L + +
Sbjct: 1038 KHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEE 1097
Query: 186 DICFSLNNNSPNIRYSENAVR----IEPNSVSLEDWLDFSSTNVEKADKQRNNS----LM 237
++ +L I NA++ +E + L++ LD KA+KQ+ +
Sbjct: 1098 ELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEA 1157
Query: 238 LKALVDRILSQTAN--DLRKQCDVVDTAFKNGLKD--------TKDARDKLADHLAKVME 287
LK ++ L TA +LR + + T K L + ++ R K A + ++ E
Sbjct: 1158 LKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTE 1217
Query: 288 EI-------ASQEKNITALEKAILDQEGPAKVAHTRLETRTHRPNVELCRDVAQYRLMKE 340
++ A+ +KN LEK D G +V L +
Sbjct: 1218 QLEQFKRAKANLDKNKQTLEKENADLAGELRV------------------------LGQA 1253
Query: 341 VQEITHNVARLKETLAQAQAELKGLHRRQLALQEEIQVKENTI 383
QE+ H +L+ + + Q++ R + L +++ +N +
Sbjct: 1254 KQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEV 1296
Score = 43.1 bits (100), Expect = 5e-04
Identities = 74/367 (20%), Positives = 138/367 (37%), Gaps = 58/367 (15%)
Query: 42 QRLVDEIEKTTRK------SQSDVNKKLEQRLEEVQFWKKELDDKLEQLVNVTDDLLIYK 95
++LV +EK RK + +++ K + + +E + K L ++ L K
Sbjct: 1447 RQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAK 1506
Query: 96 IRLEKALETLKEPLHITETCLAYREKRIGIDLVHDTVEHELIKEAEIIQGIMALLTRTLE 155
LE+ + LK + L + +G ++ HEL K ++ M + LE
Sbjct: 1507 EELERTNKMLKAEMED----LVSSKDDVGKNV------HELEKSKRALETQMEEMKTQLE 1556
Query: 156 EASEQIRMNRSAKYNLE---KDLKDKFVALTIDDICFSLNNNSPNIRYSENAVRIEPNSV 212
E ++++ AK LE + LK +F R +N E
Sbjct: 1557 ELEDELQATEDAKLRLEVNMQALKGQF-------------ERDLQARDEQN----EEKRR 1599
Query: 213 SLEDWLDFSSTNVEKADKQRNNSLMLKALVDRILSQTANDLRKQCDVVDTAFKNGLKDTK 272
L+ L T +E KQR L A + L DL Q D + +K +
Sbjct: 1600 QLQRQLHEYETELEDERKQR----ALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLR 1655
Query: 273 DARDKLADHLAKVMEEIASQ----------EKNITALEKAILD-QEGPAKVAHTRLETRT 321
+ ++ D ++ + AS+ EK +LE ++ QE A R +
Sbjct: 1656 KLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADL 1715
Query: 322 HRPNVELCRDVA-----QYRLMKEVQEITHNVARLKETLAQAQAELKGLHRRQLALQEEI 376
+ EL ++A + L E + + +A+L+E L + Q ++ + R ++
Sbjct: 1716 EKE--ELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQA 1773
Query: 377 QVKENTI 383
+ N +
Sbjct: 1774 EQLSNEL 1780
Score = 30.4 bits (67), Expect = 3.1
Identities = 33/122 (27%), Positives = 60/122 (49%), Gaps = 18/122 (14%)
Query: 263 AFKNGLKDTKDARDKLADHLAKVMEEIASQEKNITALEKAILDQEGPAKVAHTRLETRTH 322
A ++ L+ TK+ + K + L +E+ + +T EK +L ++ A+ T L
Sbjct: 863 AKEDELQKTKERQQKAENEL----KELEQKHSQLTE-EKNLLQEQLQAE---TELYAEAE 914
Query: 323 RPNVELCRDVAQYRLMKEVQEITHNV-ARLKETL---AQAQAELKGLHRRQLALQEEIQV 378
V L +E++EI H + ARL+E Q QAE K + ++ L L+E+++
Sbjct: 915 EMRVRLAAK------KQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEE 968
Query: 379 KE 380
+E
Sbjct: 969 EE 970
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 55.5 bits (132), Expect = 9e-08
Identities = 67/342 (19%), Positives = 141/342 (41%), Gaps = 49/342 (14%)
Query: 40 ESQRLVDEIEKTTRKSQSDVN--KKLEQRLEEVQFWKKELDDKLEQLVNVTDDLLIYKIR 97
E Q DE++KT + Q N K+LEQ+ ++ K L ++L+ + + ++R
Sbjct: 853 EMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVR 912
Query: 98 LEKALETLKEPLHITETCLAYREKRIGIDLVHDTVEHELIKEAEIIQGIMALLTRTLEEA 157
L + L+E LH E L E R + +Q + + + +
Sbjct: 913 LAAKKQELEEILHEMEARLEEEEDR-----------------GQQLQAERKKMAQQMLDL 955
Query: 158 SEQIRMNRSA--KYNLEKDLKDKFVALTIDDICFSLNNNSPNIRYSENAVRIEPNSVSLE 215
EQ+ +A K LEK + + D+I + N+ ++ LE
Sbjct: 956 EEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNN----------KLSKERKLLE 1005
Query: 216 DWLDFSSTNVEKADKQRNNSLMLKALVDRILSQTANDLRKQCDVVDTAFKNGLKDTKDAR 275
+ + +TN+ + +++ N LK + ++S+ L+K+ + ++ + +
Sbjct: 1006 ERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKE--------EKSRQELEKLK 1057
Query: 276 DKLADHLAKVMEEIASQEKNITALEKAILDQEGPAKVAHTRLETRTHRPNVELCRDVAQY 335
KL + E+IA + I L+ + +E + A RL+ + N
Sbjct: 1058 RKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKN---------- 1107
Query: 336 RLMKEVQEITHNVARLKETLAQAQAELKGLHRRQLALQEEIQ 377
+K+++E+ +++ L+E L +A +++ L EE++
Sbjct: 1108 NALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELE 1149
Score = 44.3 bits (103), Expect = 2e-04
Identities = 83/403 (20%), Positives = 163/403 (40%), Gaps = 70/403 (17%)
Query: 26 RADAQRSRSERLVAESQRLVDEIEKTTRKSQSDVNKKLEQRLE-EVQFWKKELDDKLEQL 84
R A++ E ++ E + ++E E ++ Q++ K +Q L+ E Q ++E + QL
Sbjct: 912 RLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQL 971
Query: 85 VNVTDDLLIYKI------------RLEKALETLKEPLHITETCLAYREKRIGIDLVHDTV 132
VT + I K+ +L K + L+E + T LA E++ +L
Sbjct: 972 EKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAK-NLTKLKN 1030
Query: 133 EHE-LIKEAEIIQGIMALLTRTLEEASEQIRMNRSAKYNLEKDLKDKFVALTI------D 185
+HE +I E E+ + LE+ ++ + S + DL+ + L + +
Sbjct: 1031 KHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEE 1090
Query: 186 DICFSLNNNSPNIRYSENAVR----IEPNSVSLEDWLDFSSTNVEKADKQRNNS----LM 237
++ +L I NA++ +E + L++ LD KA+KQ+ +
Sbjct: 1091 ELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEA 1150
Query: 238 LKALVDRILSQTAN--DLRKQCDVVDTAFKNGLKD--------TKDARDKLADHLAKVME 287
LK ++ L TA +LR + + T K L + ++ R K A + ++ E
Sbjct: 1151 LKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTE 1210
Query: 288 EI-------ASQEKNITALEKAILDQEGPAKVAHTRLETRTHRPNVELCRDVAQYRLMKE 340
++ A+ +KN LEK D G +V L +
Sbjct: 1211 QLEQFKRAKANLDKNKQTLEKENADLAGELRV------------------------LGQA 1246
Query: 341 VQEITHNVARLKETLAQAQAELKGLHRRQLALQEEIQVKENTI 383
QE+ H +L+ + + Q++ R + L +++ +N +
Sbjct: 1247 KQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEV 1289
Score = 43.1 bits (100), Expect = 5e-04
Identities = 74/367 (20%), Positives = 138/367 (37%), Gaps = 58/367 (15%)
Query: 42 QRLVDEIEKTTRK------SQSDVNKKLEQRLEEVQFWKKELDDKLEQLVNVTDDLLIYK 95
++LV +EK RK + +++ K + + +E + K L ++ L K
Sbjct: 1440 RQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAK 1499
Query: 96 IRLEKALETLKEPLHITETCLAYREKRIGIDLVHDTVEHELIKEAEIIQGIMALLTRTLE 155
LE+ + LK + L + +G ++ HEL K ++ M + LE
Sbjct: 1500 EELERTNKMLKAEMED----LVSSKDDVGKNV------HELEKSKRALETQMEEMKTQLE 1549
Query: 156 EASEQIRMNRSAKYNLE---KDLKDKFVALTIDDICFSLNNNSPNIRYSENAVRIEPNSV 212
E ++++ AK LE + LK +F R +N E
Sbjct: 1550 ELEDELQATEDAKLRLEVNMQALKGQF-------------ERDLQARDEQN----EEKRR 1592
Query: 213 SLEDWLDFSSTNVEKADKQRNNSLMLKALVDRILSQTANDLRKQCDVVDTAFKNGLKDTK 272
L+ L T +E KQR L A + L DL Q D + +K +
Sbjct: 1593 QLQRQLHEYETELEDERKQR----ALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLR 1648
Query: 273 DARDKLADHLAKVMEEIASQ----------EKNITALEKAILD-QEGPAKVAHTRLETRT 321
+ ++ D ++ + AS+ EK +LE ++ QE A R +
Sbjct: 1649 KLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADL 1708
Query: 322 HRPNVELCRDVA-----QYRLMKEVQEITHNVARLKETLAQAQAELKGLHRRQLALQEEI 376
+ EL ++A + L E + + +A+L+E L + Q ++ + R ++
Sbjct: 1709 EKE--ELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQA 1766
Query: 377 QVKENTI 383
+ N +
Sbjct: 1767 EQLSNEL 1773
Score = 30.4 bits (67), Expect = 3.1
Identities = 33/122 (27%), Positives = 60/122 (49%), Gaps = 18/122 (14%)
Query: 263 AFKNGLKDTKDARDKLADHLAKVMEEIASQEKNITALEKAILDQEGPAKVAHTRLETRTH 322
A ++ L+ TK+ + K + L +E+ + +T EK +L ++ A+ T L
Sbjct: 856 AKEDELQKTKERQQKAENEL----KELEQKHSQLTE-EKNLLQEQLQAE---TELYAEAE 907
Query: 323 RPNVELCRDVAQYRLMKEVQEITHNV-ARLKETL---AQAQAELKGLHRRQLALQEEIQV 378
V L +E++EI H + ARL+E Q QAE K + ++ L L+E+++
Sbjct: 908 EMRVRLAAK------KQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEE 961
Query: 379 KE 380
+E
Sbjct: 962 EE 963
>gi|45359873 OGT(O-Glc-NAc transferase)-interacting protein 106 KDa
isoform 2 [Homo sapiens]
Length = 686
Score = 53.5 bits (127), Expect = 3e-07
Identities = 71/320 (22%), Positives = 133/320 (41%), Gaps = 20/320 (6%)
Query: 88 TDDLLIYKIRLEKALETLKEPLHITETCLAYREKRIGIDLVHDTVEHELIKEAEIIQGIM 147
T DLL + E+ + K I EK ++L + L+K+ + +
Sbjct: 31 TQDLLEEVLCAERVGQMTKTYNDIDAVTRLLEEKERDLELAA-RIGQSLLKKNKTLTERN 89
Query: 148 ALLTRTLEEASEQIRMNRSAKYNLEKDLKDKFVALTIDDICFSLNNNSPNIRYSENAVRI 207
LL +E E++ R E +KD+ + + + P S R
Sbjct: 90 ELLEEQVEHIREEVSQLRH-----ELSMKDELLQFYTS----AAEESEPESVCSTPLKRN 140
Query: 208 EPNSVSLEDWLDFSSTNVEKADKQRNNSLMLKALVDRILSQTANDLRKQCDVVDTAFKNG 267
E +S S++++ S + D + N ++L++ ++ ++T K+ +V+ K
Sbjct: 141 ESSS-SVQNYFHLDSLQKKLKDLEEEN-VVLRSEASQLKTETITYEEKEQQLVNDCVKE- 197
Query: 268 LKDTKDARDKLADHLAKVMEEIASQEKNITALEKAILDQEGPAKVAHTRLETRTHRPNVE 327
L+D +++ LAK E+ A Q++ IT L I+D + AK E ++
Sbjct: 198 LRDANVQIASISEELAKKTEDAARQQEEITHLLSQIVDLQKKAKACAVENEELVQ--HLG 255
Query: 328 LCRDVAQYRLMKEVQEITHNVARLKETLAQAQAELKGLHRRQLALQEEIQVKENTIYIDE 387
+D AQ +L E++E+ A E L +AQ ELK L + + + ++ +
Sbjct: 256 AAKD-AQRQLTAELRELEDKYAECMEMLHEAQEELKNLRNKTMPNTTSRRYHSLGLFPMD 314
Query: 388 VLCMQ----MRKSIPLRDGE 403
L + MRK + L + E
Sbjct: 315 SLAAEIEGTMRKELQLEEAE 334
>gi|190341068 forkhead-associated (FHA) phosphopeptide binding domain
1 [Homo sapiens]
Length = 1412
Score = 53.1 bits (126), Expect = 4e-07
Identities = 79/408 (19%), Positives = 176/408 (43%), Gaps = 64/408 (15%)
Query: 30 QRSRSERLVAESQRLVDEIE-------KTTRKSQSDVNKKLEQRLEEVQFWKKELDDKLE 82
+R+R++ + E ++ + E+E K KS + ++++ LEE Q +EL+++L
Sbjct: 697 ERNRAKETLEEERKRMQELESLLAQQKKALAKSITQEKNRVKEALEEEQTRVQELEERLA 756
Query: 83 QLVNVTDDLLIY-KIRLEKALETLKEPLHITETCLAYREKRIGIDLVHD--TVEHELIKE 139
+ V + + + K + ++ALE+ K + E L +++ ++ ++ + + KE
Sbjct: 757 RQKEVLESSIAHEKRKAKEALESEKRKVQDLENHLTQQKEISESNIAYEKRKAKEAMEKE 816
Query: 140 AEIIQGIMALLTR-----TLEEASEQIRMNR----------SAKYNLEKDLKDKFVALTI 184
+ +Q + LT+ L+E E + N+ + K + LK + +AL +
Sbjct: 817 KKKVQDLENRLTKQKEELELKEQKEDVLNNKLSDALAMVEETQKTKATESLKAESLALKL 876
Query: 185 DDICFSLNNNSPNIRYSENAVRIEPNSV-SLEDWLD-----FSSTNVEKADKQRNNSLML 238
++ L + E + ++ V +L+D + F +E ++ + ++ +
Sbjct: 877 NETLAELETTKTKMIMVEERLILQQKMVKALQDEQESQRHGFEEEIMEYKEQIKQHAQTI 936
Query: 239 KALVDRILSQTAN-------------------DLRKQCDVVDTAFKNGLKDTKDARDKLA 279
+L +++ T + + R Q +V ++ KD A + L
Sbjct: 937 VSLEEKLQKVTQHHKKIEGEIATLKDNDPAPKEERPQDPLVAPMTESSAKDM--AYEHLI 994
Query: 280 DHLAKVMEEIASQEKNITALEKAILDQEGPAKVAHTRLETRTHRPNVELCRDVAQYRLM- 338
D L +EI SQ++ I L K + + AH+R+ N + ++ Q ++
Sbjct: 995 DDLLAAQKEILSQQEVIMKLRKDLTE-------AHSRMSDLRGELNEKQKMELEQNVVLV 1047
Query: 339 ----KEVQEITHNVARLKETLAQAQAELKGLHRRQLALQEEIQVKENT 382
KE+ + +A++ + + ELK L A QE+ +++ NT
Sbjct: 1048 QQQSKELSVLKEKMAQMSSLVEKKDRELKALEEALRASQEKHRLQLNT 1095
>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
Length = 1411
Score = 52.4 bits (124), Expect = 8e-07
Identities = 77/390 (19%), Positives = 159/390 (40%), Gaps = 48/390 (12%)
Query: 32 SRSERLVAESQRLVDEIEKTTRKSQSDVNKKLEQRLEEVQFWKKELDDKLEQLVNVTDDL 91
S+ E + E + +E+ T + + + KKLE EV+ K++ L+Q + DL
Sbjct: 705 SQLESHLKEYKEKYLSLEQKTEELEGQI-KKLEADSLEVKASKEQALQDLQQQRQLNTDL 763
Query: 92 LIYKIRLEKALETLKEPLHITETCLAYREKRIGIDLVHDTVEHELIKEAEIIQGIMALLT 151
+ L K LE KE + T L + + + ++++ +L K+ E Q +L
Sbjct: 764 ELRATELSKQLEMEKEIVSSTRLDLQKKSEAL------ESIKQKLTKQEEEKQ----ILK 813
Query: 152 RTLEEASEQIRMNRSAKYN--------LEKDLKDKFVALT--------IDDICFSLNNN- 194
+ E S++ ++ N L+K +K +T + + SL N+
Sbjct: 814 QDFETLSQETKIQHEELNNRIQTTVTELQKVKMEKEALMTELSTVKDKLSKVSDSLKNSK 873
Query: 195 ----SPNIRYSENAVRIEPNSVSLEDWLDFSSTNVEKADKQRNNSLMLKALVDRILSQTA 250
N + + +E L+ L N K K+ SL + L
Sbjct: 874 SEFEKENQKGKAAILDLEKTCKELKHQLQVQMENTLKEQKELKKSLEKEKEASHQLKLEL 933
Query: 251 NDLRKQCDVVDTAFKNGLKDTKDARDKLADHLAKVMEEIASQEKNITALEKAILDQEGPA 310
N +++Q +N LK + +L ++ ++ + ++K I AL +G
Sbjct: 934 NSMQEQL----IQAQNTLKQNEKEEQQLQGNINELKQSSEQKKKQIEAL-------QGEL 982
Query: 311 KVA---HTRLETRTHRPNVELCRDVAQYRLMKEVQEITHNVARLKETLAQAQAELKGLHR 367
K+A T LE + + + +++A + +++ + +N + +ET Q Q++ G
Sbjct: 983 KIAVLQKTELENKLQQQLTQAAQELAAEK--EKISVLQNNYEKSQETFKQLQSDFYGRES 1040
Query: 368 RQLALQEEIQVKENTIYIDEVLCMQMRKSI 397
LA +++++ E + + + + R I
Sbjct: 1041 ELLATRQDLKSVEEKLSLAQEDLISNRNQI 1070
Score = 46.2 bits (108), Expect = 5e-05
Identities = 77/402 (19%), Positives = 169/402 (42%), Gaps = 67/402 (16%)
Query: 26 RADAQRSRSERLVAESQRLVDEIEKTTRKSQSDVNKKLEQRLEEVQFWKKELDDKLEQLV 85
R D Q+ +SE L + Q+L + E+ + + + E +E + +EL+++++ V
Sbjct: 785 RLDLQK-KSEALESIKQKLTKQEEE-----KQILKQDFETLSQETKIQHEELNNRIQTTV 838
Query: 86 NVTDDLLIYKIRLEKALETLKEPLHITETCLAYREKRIGIDLVHDTVEHELIKEAEIIQG 145
+ + K L L T+K+ L ++ L + E E KE + +
Sbjct: 839 TELQKVKMEKEALMTELSTVKDKL-----------SKVSDSLKNSKSEFE--KENQKGKA 885
Query: 146 IMALLTRTLEEASEQIRMNRSAKYNLEKDLKDKFVALTIDDICFSLNNNSPNIRYSENAV 205
+ L +T +E Q+++ +K+LK SL + + + +
Sbjct: 886 AILDLEKTCKELKHQLQVQMENTLKEQKELKK------------SLEKE----KEASHQL 929
Query: 206 RIEPNSVSLEDWLDFSSTNVEKADKQRNNSLMLKALVDRILSQTANDLRKQCDVVDTAFK 265
++E NS +++ L + +++ +K+ L+ ++ L Q++ +KQ + + K
Sbjct: 930 KLELNS--MQEQLIQAQNTLKQNEKEEQQ---LQGNINE-LKQSSEQKKKQIEALQGELK 983
Query: 266 NGLKDTKDARDKLADHLAKVMEEIASQEKNITALEKAILDQEGPAKVAHT--------RL 317
+ + +KL L + +E+A++++ I+ L+ + K + L
Sbjct: 984 IAVLQKTELENKLQQQLTQAAQELAAEKEKISVLQNNYEKSQETFKQLQSDFYGRESELL 1043
Query: 318 ETRTHRPNVELCRDVAQYRLM----------KEVQEITHNVARLKETLAQAQAELKGLHR 367
TR +VE +AQ L+ K +QE+ A L++ A+ + +L+ +
Sbjct: 1044 ATRQDLKSVEEKLSLAQEDLISNRNQIGNQNKLIQELKTAKATLEQDSAKKEQQLQERCK 1103
Query: 368 RQLALQEEIQVKENTIY--------IDEVLCMQMRKSIPLRD 401
+Q+E +KE + I+E+ C Q ++ L +
Sbjct: 1104 ALQDIQKEKSLKEKELVNEKSKLAEIEEIKCRQEKEITKLNE 1145
Score = 42.7 bits (99), Expect = 6e-04
Identities = 76/353 (21%), Positives = 145/353 (41%), Gaps = 37/353 (10%)
Query: 38 VAESQRLVDEIEKTTRKSQSDVNKKLEQRLEEVQFWK-KELDDKLEQLVNVTDDLLIYKI 96
V S L +++KT ++ Q +Q L++ K +E + LEQ++ D
Sbjct: 473 VTNSTELQHQLDKTKQQHQE------QQALQQSTTAKLREAQNDLEQVLRQIGDKDQKIQ 526
Query: 97 RLEKALETLKEPLHITETCLAYREKRIGIDLVHDTVEHELIKEAEIIQGIMALLTRTLEE 156
LE L+ KE + + E +I V ++L ++ +Q + LT L+
Sbjct: 527 NLEALLQKSKENISLLEKEREDLYAKIQAGEGETAVLNQLQEKNHTLQEQVTQLTEKLKN 586
Query: 157 ASEQIRMNRSAKYNLEKDLKDKFVAL-TIDDICFSLNN--NSPNIRYSENAVRIEPNSVS 213
SE ++ A+ NL ++++ L D SL N N + +E+ ++ +
Sbjct: 587 QSES---HKQAQENLHDQVQEQKAHLRAAQDRVLSLETSVNELNSQLNESKEKVSQLDIQ 643
Query: 214 LEDWLDF-----SSTNVEKADKQRNNSLMLKALVDRILSQTANDLRKQCDVVDTAFKNGL 268
++ + ++ ++AD Q + AL D+ Q N + Q D V L
Sbjct: 644 IKAKTELLLSAEAAKTAQRADLQNHLDTAQNALQDK--QQELNKITTQLDQVTAK----L 697
Query: 269 KDTKDARDKLADHLAKVMEEIASQEKNITALEKAILDQEGPAKVAHTRLETRTHRPNVEL 328
+D ++ +L HL + E+ S E+ LE I K+ LE + + +
Sbjct: 698 QDKQEHCSQLESHLKEYKEKYLSLEQKTEELEGQI------KKLEADSLEVKASKE--QA 749
Query: 329 CRDVAQYRLMKEVQEITHNVARLKETLAQAQAELKGLHRRQLALQEEIQVKEN 381
+D+ Q R + E+ R E Q + E + + +L LQ++ + E+
Sbjct: 750 LQDLQQQRQLNTDLEL-----RATELSKQLEMEKEIVSSTRLDLQKKSEALES 797
Score = 37.0 bits (84), Expect = 0.033
Identities = 69/337 (20%), Positives = 142/337 (42%), Gaps = 44/337 (13%)
Query: 63 LEQRLEEVQFWKKELDDKLE-----QLVNVTDDLLIYKIRLEKALETLKEPLHITETCLA 117
L+ L+E +++ +EL +LE Q D L+ E L++L++ L +T
Sbjct: 95 LQASLKEEKWYSEELKKELEKYQGLQQQEAKPDGLVTDSSAE--LQSLEQQLEEAQT--- 149
Query: 118 YREKRIGIDLVHDTVEHELIKEAEIIQGIMALLT--RTLEEASEQIRMNRSAKYNLEKDL 175
+ I + D E + + A I I + R+L EA+EQ + + N E
Sbjct: 150 ---ENFNIKQMKDLFEQKAAQLATEIADIKSKYDEERSLREAAEQKVTRLTEELNKE--- 203
Query: 176 KDKFVALTIDDICFSLNNNSPNIRYSENAVRIEPNSVSLEDWLDFSSTNVEK-ADKQRNN 234
A I D+ L P I E+ ++ V ++ +D + E+ ++K ++
Sbjct: 204 -----ATVIQDLKTELLQR-PGI---EDVAVLKKELVQVQTLMDNMTLERERESEKLKDE 254
Query: 235 SLMLK---ALVDRILSQTANDLRKQCDVVDTAFKNGLKDTKDARDKLADHLAKVMEEIAS 291
L+ A + +SQ ++L K V + L+ K + ++L + E +
Sbjct: 255 CKKLQSQYASSEATISQLRSELAKGPQEV-AVYVQELQKLKSSVNELTQKNQTLTENLLK 313
Query: 292 QEKNITALEKAILDQEGPAKVAHTRLETRTHRPNVEL--------CRDVAQYRLMKEVQE 343
+E++ T LE ++ V+ ++ H+ +++ + + +R+ E+ E
Sbjct: 314 KEQDYTKLE----EKHNEESVSKKNIQATLHQKDLDCQQLQSRLSASETSLHRIHVELSE 369
Query: 344 ITHNVARLKETLAQAQAELKGLHRRQLALQEEIQVKE 380
+LKE L++ + + + L LQ++ + KE
Sbjct: 370 KGEATQKLKEELSEVETKYQHLKAEFKQLQQQREEKE 406
Score = 34.3 bits (77), Expect = 0.22
Identities = 64/291 (21%), Positives = 119/291 (40%), Gaps = 53/291 (18%)
Query: 135 ELIKEAEIIQGIM-------ALLTRT---LEEASEQIRMNRSAKYNLEKDLKDKF----- 179
EL KE E QG+ L+T + L+ +Q+ ++ +N+ K +KD F
Sbjct: 108 ELKKELEKYQGLQQQEAKPDGLVTDSSAELQSLEQQLEEAQTENFNI-KQMKDLFEQKAA 166
Query: 180 -VALTIDDICFSLNNNSPNIRYSENAVRIEPNSVSLEDWLDFSSTNV-EKADKQRNNSLM 237
+A I DI +Y E SL + + T + E+ +K+
Sbjct: 167 QLATEIADI---------KSKYDEER--------SLREAAEQKVTRLTEELNKEATVIQD 209
Query: 238 LKA-LVDRILSQTANDLRKQCDVVDTAFKNGLKDTKDARDKLADHLAKVMEEIASQEKNI 296
LK L+ R + L+K+ V T N + + +KL D K+ + AS E I
Sbjct: 210 LKTELLQRPGIEDVAVLKKELVQVQTLMDNMTLERERESEKLKDECKKLQSQYASSEATI 269
Query: 297 TALEKAILDQEGPAKVAHTRLETRTHRPNVELCRDVAQYRLMKEVQEITHNVARLKETLA 356
+ L + +GP +VA E + + +V L ++ Q +T N+ + +
Sbjct: 270 SQLRSEL--AKGPQEVAVYVQELQKLKSSVN--------ELTQKNQTLTENLLKKE---- 315
Query: 357 QAQAELKGLHRRQLALQEEIQVKENTIYIDEVLCMQMRKSIPLRDGEDHGV 407
Q +L+ H + ++ IQ T++ ++ C Q++ + + H +
Sbjct: 316 QDYTKLEEKHNEESVSKKNIQA---TLHQKDLDCQQLQSRLSASETSLHRI 363
Score = 32.3 bits (72), Expect = 0.82
Identities = 85/368 (23%), Positives = 138/368 (37%), Gaps = 60/368 (16%)
Query: 38 VAESQRLVDEIEKTTRKSQS----------DVNKKLEQRLEE--------VQFWKKELDD 79
V E Q+L + + T+K+Q+ D K E+ EE +K+LD
Sbjct: 287 VQELQKLKSSVNELTQKNQTLTENLLKKEQDYTKLEEKHNEESVSKKNIQATLHQKDLDC 346
Query: 80 KLEQLVNVTDDLLIYKIRLE-----KALETLKEPLHITETCLAYREKRIGIDLV----HD 130
+ Q + +++I +E +A + LKE L ET Y+ + + +
Sbjct: 347 QQLQSRLSASETSLHRIHVELSEKGEATQKLKEELSEVET--KYQHLKAEFKQLQQQREE 404
Query: 131 TVEHELIKEAEIIQGIMALLTRTLEEASEQIRMNRSAKYNLEKDLKDKFVALTIDDICFS 190
+H L ++EI Q LL + R+ + + EK L DK + D+
Sbjct: 405 KEQHGLQLQSEINQLHSKLLETERQLGEAHGRLKEQRQLSSEK-LMDK--EQQVADLQLK 461
Query: 191 LNNNSPNIRYSENAVRIEPNSVSLEDWLDFSSTNVEKADKQRNNSLMLKALVDRILSQTA 250
L+ R E NS L+ LD K +Q L+ L +
Sbjct: 462 LS------RLEEQLKEKVTNSTELQHQLD-------KTKQQHQEQQALQQSTTAKLREAQ 508
Query: 251 NDLRKQCDVVDTAFKNGLKDTKDARDKLADHLAKVMEEIASQEKNITALEKAILDQEGPA 310
NDL + + G KD K L L K E I+ EK L I EG
Sbjct: 509 NDLEQVLRQI------GDKDQK--IQNLEALLQKSKENISLLEKEREDLYAKIQAGEGET 560
Query: 311 KVAHTRLETRTHRPNVELCRDVAQYRLMKEVQEITHNVAR--LKETLAQAQAELKGLHRR 368
V + +L+ + H L V Q + Q +H A+ L + + + +A L+ R
Sbjct: 561 AVLN-QLQEKNH----TLQEQVTQLTEKLKNQSESHKQAQENLHDQVQEQKAHLRAAQDR 615
Query: 369 QLALQEEI 376
L+L+ +
Sbjct: 616 VLSLETSV 623
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 51.6 bits (122), Expect = 1e-06
Identities = 92/416 (22%), Positives = 178/416 (42%), Gaps = 50/416 (12%)
Query: 3 KLLQPPPKFLPSEWHIANK-NQYHRADAQRSRSERLVAESQR-LVDEIEKTTRKSQSD-- 58
KL Q K +A K + R + + ++ +AE + L ++E+ ++ Q+
Sbjct: 1650 KLSQEAEKLAQKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVEELPQREQNLDW 1709
Query: 59 VNKKLEQRLEEVQFWKKELDDKLEQLVNVTDDLLIYKIRL---EKALETLKEPLHITETC 115
K+L Q LEE+++ +EL K E+L L+ K +L E+AL +E L ET
Sbjct: 1710 QEKELAQELEELEWDMEELSWKEEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETK 1769
Query: 116 LAYREKRIGIDLVHDTVEHELIKEAEIIQGIMALLTRTLEEASEQIRMNRSAKYNLEKDL 175
LA E+ LI+E E L + E+ R+ R + +EK +
Sbjct: 1770 LAQEEEL-------------LIQEKE------KLAQHKEKMPEEEERLGRKREQLIEKKM 1810
Query: 176 KDKFVALTIDDICFSLNNNSPNIRYSENAVRIEPNSVSLEDWLDFSSTNV----EKADKQ 231
K + L N + +N + + N ++ L N+ E+
Sbjct: 1811 KLAQKRERWINSMEELTKNKMILYQKKNLAQEKKNLAQEKEKLAQRKENLLYNKERLTHS 1870
Query: 232 RNNSLMLK---ALVDRILSQTANDLRKQCDVVDTAFKNGLKDTKDARDKLADHLAKVMEE 288
+ + +K + ++IL+Q L ++ + V K L +T+ ++ D LAK E+
Sbjct: 1871 KKQLVQVKNKLGMFNKILAQVEEKLTQEKETV-IKKKEKLAETEKKLVQVEDSLAKKQEK 1929
Query: 289 IASQEKNITALEKAILDQEGPAKVAHTRLETRTHRPNVELCRDVAQYRL-MKEVQEITHN 347
+A QEK ALEKA++ +G ++ R +++ ++ L MK + E
Sbjct: 1930 LA-QEKMKLALEKAMV--QGKKRL----------RGELDIAKEEKALNLEMKRLAEEKMR 1976
Query: 348 VARLKETLAQAQAELKGLHRRQLALQEEIQVKENTIYIDEVLCMQMRKSIPLRDGE 403
+ KETL++ + R+ +++E+ E + ++E + + + + + + E
Sbjct: 1977 LVEGKETLSKGETPETSRQRKMTQVEQEL--FERKLSLEEKILLHEDRILAMEESE 2030
>gi|111074532 OGT(O-Glc-NAc transferase)-interacting protein 106 KDa
isoform 1 [Homo sapiens]
Length = 953
Score = 51.6 bits (122), Expect = 1e-06
Identities = 61/254 (24%), Positives = 111/254 (43%), Gaps = 15/254 (5%)
Query: 154 LEEASEQIRMNRSAKYNLEKDLKDKFVALTIDDICFSLNNNSPNIRYSENAVRIEPNSVS 213
LEE E IR S + E +KD+ + + + P S R E +S S
Sbjct: 150 LEEQVEHIREEVS-QLRHELSMKDELLQFYTS----AAEESEPESVCSTPLKRNESSS-S 203
Query: 214 LEDWLDFSSTNVEKADKQRNNSLMLKALVDRILSQTANDLRKQCDVVDTAFKNGLKDTKD 273
++++ S + D + N ++L++ ++ ++T K+ +V+ K L+D
Sbjct: 204 VQNYFHLDSLQKKLKDLEEEN-VVLRSEASQLKTETITYEEKEQQLVNDCVKE-LRDANV 261
Query: 274 ARDKLADHLAKVMEEIASQEKNITALEKAILDQEGPAKVAHTRLETRTHRPNVELCRDVA 333
+++ LAK E+ A Q++ IT L I+D + AK E ++ +D A
Sbjct: 262 QIASISEELAKKTEDAARQQEEITHLLSQIVDLQKKAKACAVENEELVQ--HLGAAKD-A 318
Query: 334 QYRLMKEVQEITHNVARLKETLAQAQAELKGLHRRQLALQEEIQVKENTIYIDEVLCMQ- 392
Q +L E++E+ A E L +AQ ELK L + + + ++ + L +
Sbjct: 319 QRQLTAELRELEDKYAECMEMLHEAQEELKNLRNKTMPNTTSRRYHSLGLFPMDSLAAEI 378
Query: 393 ---MRKSIPLRDGE 403
MRK + L + E
Sbjct: 379 EGTMRKELQLEEAE 392
>gi|216548091 leucine zipper protein 1 [Homo sapiens]
Length = 1076
Score = 51.2 bits (121), Expect = 2e-06
Identities = 68/297 (22%), Positives = 127/297 (42%), Gaps = 40/297 (13%)
Query: 28 DAQRSRSERLVAESQRLVDEIEKTTRKSQSDVNKKLEQRLEEVQFWKKELDDKLEQLVNV 87
D + R+E L + ++E E TR+ +S++ ++L++R+ E++ +L++ + N
Sbjct: 79 DEEIKRAEDLCRLMKEKLEEEENLTRELKSEI-ERLQKRMAELE----KLEEAFSRSKND 133
Query: 88 TDDL---LIYKIRLEKALETLKEPLHITETCLAYREKRIGIDLVHDTVEHELIKEAEIIQ 144
L L + L K + + E L + L E R+ D E L E E ++
Sbjct: 134 CTQLCLSLNEERNLTKKISSELEMLRVKVKELESSEDRL------DKTEQSLASELEKLK 187
Query: 145 GIMALLTRTLEEASEQIRMNRSAKYNLEKDLKDKFVALTIDDICFSLNNNSPNIRYSENA 204
+ TL SE+ +N K N EK +K+ L N N Y+ NA
Sbjct: 188 SL------TLSFVSERKYLNEKEKEN-EKLIKELTQKLE--------QNKKMNRDYTRNA 232
Query: 205 VRIEPNSVSLEDWLDFSSTNVEKADKQRNNSLMLKALVDRILSQTANDLRKQCDVVDTAF 264
+E N + +ED + SST K +++ LK + + +++ N+ + +
Sbjct: 233 SNLERNDLRIEDGI--SSTLPSKESRRKGGLDYLKQVENETRNKSENEKNRNQE------ 284
Query: 265 KNGLKDTKDARDKL---ADHLAKVMEEIASQEKNITALEKAILDQEGPAKVAHTRLE 318
N +KD +KL H + EE+ + L+ L ++ K+ ++LE
Sbjct: 285 DNKVKDLNQEIEKLKTQIKHFESLEEELKKMKSKNNDLQDNYLSEQNKNKLLASQLE 341
Score = 32.0 bits (71), Expect = 1.1
Identities = 45/209 (21%), Positives = 91/209 (43%), Gaps = 27/209 (12%)
Query: 201 SENAVRIEPNSVSLE-DWLDFSSTNVEKADKQRNNSLMLKALVDRILSQTANDLRKQCDV 259
S +R + S+S D L+ ++ N++KA+ + L L D+++ ++ ++
Sbjct: 12 SSRHLRFKLQSLSRRLDELEEATKNLQKAEDE------LLDLQDKVIQAEGSNSSMLAEI 65
Query: 260 VDTAFKNGLKDTKDARDKLADHLAKVMEEIASQEKNITALEKAILDQEGPAKVAHTRLE- 318
+ + KD K A+ L ++M+E +E+N+T K+ +++ +LE
Sbjct: 66 EVLRQRVLRIEGKDEEIKRAEDLCRLMKEKLEEEENLTRELKSEIERLQKRMAELEKLEE 125
Query: 319 --TRTHRPNVELCRDVAQYR------------LMKEVQEITHNVARLKETLAQAQAELKG 364
+R+ +LC + + R L +V+E+ + RL +T +EL+
Sbjct: 126 AFSRSKNDCTQLCLSLNEERNLTKKISSELEMLRVKVKELESSEDRLDKTEQSLASELEK 185
Query: 365 LHRRQLALQEEIQV-----KENTIYIDEV 388
L L+ E + KEN I E+
Sbjct: 186 LKSLTLSFVSERKYLNEKEKENEKLIKEL 214
>gi|216548085 leucine zipper protein 1 [Homo sapiens]
Length = 1076
Score = 51.2 bits (121), Expect = 2e-06
Identities = 68/297 (22%), Positives = 127/297 (42%), Gaps = 40/297 (13%)
Query: 28 DAQRSRSERLVAESQRLVDEIEKTTRKSQSDVNKKLEQRLEEVQFWKKELDDKLEQLVNV 87
D + R+E L + ++E E TR+ +S++ ++L++R+ E++ +L++ + N
Sbjct: 79 DEEIKRAEDLCRLMKEKLEEEENLTRELKSEI-ERLQKRMAELE----KLEEAFSRSKND 133
Query: 88 TDDL---LIYKIRLEKALETLKEPLHITETCLAYREKRIGIDLVHDTVEHELIKEAEIIQ 144
L L + L K + + E L + L E R+ D E L E E ++
Sbjct: 134 CTQLCLSLNEERNLTKKISSELEMLRVKVKELESSEDRL------DKTEQSLASELEKLK 187
Query: 145 GIMALLTRTLEEASEQIRMNRSAKYNLEKDLKDKFVALTIDDICFSLNNNSPNIRYSENA 204
+ TL SE+ +N K N EK +K+ L N N Y+ NA
Sbjct: 188 SL------TLSFVSERKYLNEKEKEN-EKLIKELTQKLE--------QNKKMNRDYTRNA 232
Query: 205 VRIEPNSVSLEDWLDFSSTNVEKADKQRNNSLMLKALVDRILSQTANDLRKQCDVVDTAF 264
+E N + +ED + SST K +++ LK + + +++ N+ + +
Sbjct: 233 SNLERNDLRIEDGI--SSTLPSKESRRKGGLDYLKQVENETRNKSENEKNRNQE------ 284
Query: 265 KNGLKDTKDARDKL---ADHLAKVMEEIASQEKNITALEKAILDQEGPAKVAHTRLE 318
N +KD +KL H + EE+ + L+ L ++ K+ ++LE
Sbjct: 285 DNKVKDLNQEIEKLKTQIKHFESLEEELKKMKSKNNDLQDNYLSEQNKNKLLASQLE 341
Score = 32.0 bits (71), Expect = 1.1
Identities = 45/209 (21%), Positives = 91/209 (43%), Gaps = 27/209 (12%)
Query: 201 SENAVRIEPNSVSLE-DWLDFSSTNVEKADKQRNNSLMLKALVDRILSQTANDLRKQCDV 259
S +R + S+S D L+ ++ N++KA+ + L L D+++ ++ ++
Sbjct: 12 SSRHLRFKLQSLSRRLDELEEATKNLQKAEDE------LLDLQDKVIQAEGSNSSMLAEI 65
Query: 260 VDTAFKNGLKDTKDARDKLADHLAKVMEEIASQEKNITALEKAILDQEGPAKVAHTRLE- 318
+ + KD K A+ L ++M+E +E+N+T K+ +++ +LE
Sbjct: 66 EVLRQRVLRIEGKDEEIKRAEDLCRLMKEKLEEEENLTRELKSEIERLQKRMAELEKLEE 125
Query: 319 --TRTHRPNVELCRDVAQYR------------LMKEVQEITHNVARLKETLAQAQAELKG 364
+R+ +LC + + R L +V+E+ + RL +T +EL+
Sbjct: 126 AFSRSKNDCTQLCLSLNEERNLTKKISSELEMLRVKVKELESSEDRLDKTEQSLASELEK 185
Query: 365 LHRRQLALQEEIQV-----KENTIYIDEV 388
L L+ E + KEN I E+
Sbjct: 186 LKSLTLSFVSERKYLNEKEKENEKLIKEL 214
>gi|114155142 nuclear pore complex-associated protein TPR [Homo
sapiens]
Length = 2363
Score = 51.2 bits (121), Expect = 2e-06
Identities = 74/365 (20%), Positives = 152/365 (41%), Gaps = 47/365 (12%)
Query: 24 YHRADAQRSRSERLVAESQRLVD----EIEKTTRKSQSDVNKKLEQRLEEVQFWKKELDD 79
Y + + +++RL+ + L + E ++TT +++ KLE L E++ +K
Sbjct: 540 YRNIEELQQQNQRLLVALRELGETREREEQETTSSKITELQLKLESALTELEQLRKSRQH 599
Query: 80 KLEQLVNVTDDLLIYKIRLEKALETLKEPLH---ITETCLAYREKRIGI-DLVHDTVEHE 135
+++ + ++ +Y+I L + + PLH + + LA KR V
Sbjct: 600 QMQLVDSIVRQRDMYRILLSQT-TGVAIPLHASSLDDVSLASTPKRPSTSQTVSTPAPVP 658
Query: 136 LIKEAEIIQGIMALLTRTLEEASEQIRMNRSAKYNLEKDLKDKFVALTIDDICFSLNNNS 195
+I+ E I+ AL + L+E E + ++ ++ + +K
Sbjct: 659 VIESTEAIEAKAAL--KQLQEIFENYKKEKAENEKIQNEQLEKL---------------- 700
Query: 196 PNIRYSENAVRIEPNSVSLEDWLDFSSTNVEK-ADKQRNNSLMLKALVDRILSQTANDLR 254
E + + + LDF+S E D + +L +R TA +
Sbjct: 701 -----QEQVTDLRSQNTKISTQLDFASKRYEMLQDNVEGYRREITSLHERNQKLTAT-TQ 754
Query: 255 KQCDVVDTAFKNGLKDTKDARDKLADHLAKVMEEIASQEKNITALEKAILDQEGPAKVAH 314
KQ +++T +D + A +KLA +A+V E +EK + L + L Q+ + +A
Sbjct: 755 KQEQIINTM----TQDLRGANEKLA--VAEVRAENLKKEKEMLKLSEVRLSQQRESLLAE 808
Query: 315 TR------LETRTHRPNVELCRDVAQYRLMKEVQEITHNVARLKETLAQAQAELKGLHRR 368
R +T + +E + RL +++++ H ++ LK+ L + + E + R
Sbjct: 809 QRGQNLLLTNLQTIQGILERSETETKQRLSSQIEKLEHEISHLKKKL-ENEVEQRHTLTR 867
Query: 369 QLALQ 373
L +Q
Sbjct: 868 NLDVQ 872
Score = 41.6 bits (96), Expect = 0.001
Identities = 87/432 (20%), Positives = 176/432 (40%), Gaps = 73/432 (16%)
Query: 9 PKFLPSEWHIANKNQYHRADAQRSRSERLVAESQRLVDEIEKTTRKSQSD-VNKKLEQRL 67
PK + ++ +Q D + R E+ ES++ EIEK SQ VN+ E
Sbjct: 18 PKSVQNKLEKFLADQQSEIDGLKGRHEKFKVESEQQYFEIEKRLSHSQERLVNETRE--C 75
Query: 68 EEVQFWKKELDDKLEQLVNVTDDLLIYK---IRLEKALETLKEPLHITETCLAYREKRIG 124
+ ++ ++L+++L+ L +L I + I ++ KE L + L +R+
Sbjct: 76 QSLRLELEKLNNQLKALTEKNKELEIAQDRNIAIQSQFTRTKEELEAEKRDLIRTNERLS 135
Query: 125 IDLVHDTVE----HELIKEAEIIQGIMALLTRTLEEASEQIRMNRSAKYNLEKDL----- 175
+L + T + +E +KE+ +G + L L+ + ++ R + EK+L
Sbjct: 136 QELEYLTEDVKRLNEKLKESNTTKGELQLKLDELQASDVSVKY-REKRLEQEKELLHSQN 194
Query: 176 ----------KDKFVAL------TIDDICFSLNNNSPNI-RYSENAVRIEPNSVSLEDWL 218
D+ +AL I ++ +L N + R E ++ ++ L+ +
Sbjct: 195 TWLNTELKTKTDELLALGREKGNEILELKCNLENKKEEVSRLEEQMNGLKTSNEHLQKHV 254
Query: 219 DFSSTNVEKADKQR-------NNSLMLKALVDRILSQTANDLRKQCDVVDTAFK---NGL 268
+ T +++A +Q+ +N L + + A+D + + + A + L
Sbjct: 255 EDLLTKLKEAKEQQASMEEKFHNELNAHIKLSNLYKSAADDSEAKSNELTRAVEELHKLL 314
Query: 269 KDTKDARDKLADHLAKVMEEIASQEKNITALEKAILDQEGPAKVAHTRLETRTHRPNVEL 328
K+ +A + DHL +V E++ +EK +L++ G RLE N L
Sbjct: 315 KEAGEANKAIQDHLLEV-------EQSKDQMEKEMLEKIG-------RLEKELENANDLL 360
Query: 329 CRDVAQYRLMKEVQEITHNVARLKETLAQAQAELK-GLHRRQL----------ALQEEIQ 377
+ ++ E +A + T A +K G+ +L L E+++
Sbjct: 361 SATKRKGAILSE-----EELAAMSPTAAAVAKIVKPGMKLTELYNAYVETQDQLLLEKLE 415
Query: 378 VKENTIYIDEVL 389
K Y+DE++
Sbjct: 416 NKRINKYLDEIV 427
Score = 40.0 bits (92), Expect = 0.004
Identities = 68/377 (18%), Positives = 160/377 (42%), Gaps = 47/377 (12%)
Query: 29 AQRSRSERLVAESQRLVDEIEKTTRKSQSDVNKKLEQRLEEVQFWKKELDDKLEQLVNVT 88
A++ L+ Q + +E++ +++ ++ ++E+ E+ KK+L++++EQ +T
Sbjct: 807 AEQRGQNLLLTNLQTIQGILERSETETKQRLSSQIEKLEHEISHLKKKLENEVEQRHTLT 866
Query: 89 DDLLIYKIRLEKALETLKEPLHI-TETCLAYREKRIGIDLVH-DTVEHELIKEA------ 140
+L + + ++ L+T + LH+ T+ L +K I H +E ++ ++
Sbjct: 867 RNLDVQLLDTKRQLDT-ETNLHLNTKELLKNAQKEIATLKQHLSNMEVQVASQSSQRTGK 925
Query: 141 ------EIIQGIMALLTRTLEEASEQIRMNRSAKYNLEKDLKDKFVALTIDDICFSLNNN 194
E + +++ L +T E+ ++ +++ N+E+ + + SLN
Sbjct: 926 GQPSNKEDVDDLVSQLRQTEEQVNDLKERLKTSTSNVEQ------YQAMVTSLEESLNKE 979
Query: 195 SPNIRYSENAVRIE-PNSVSLEDWLDFSSTNVEKA------DKQRNNSLMLKAL--VDRI 245
+ + S + L+ VEK DK+R M + L + +
Sbjct: 980 KQVTEEVRKNIEVRLKESAEFQTQLEKKLMEVEKEKQELQDDKRRAIESMEQQLSELKKT 1039
Query: 246 LSQTANDLRKQCDVVDTAFKNGLKDTKDARDK---LADHLAKVMEEIASQEKNITALEKA 302
LS N++++ TA N + +D +++ + K E+ ++ AL+ A
Sbjct: 1040 LSSVQNEVQEALQRASTALSNEQQARRDCQEQAKIAVEAQNKYERELMLHAADVEALQAA 1099
Query: 303 ILDQEGPAKVAHTR--LETRTHRPNVELCRDVAQYRLMKEVQEITHNVARLKETLAQAQA 360
+E +K+A R LE T + +L A + + + LK+ +++
Sbjct: 1100 ---KEQVSKMASVRQHLEETTQKAESQLLECKASWEERERM---------LKDEVSKCVC 1147
Query: 361 ELKGLHRRQLALQEEIQ 377
+ L ++ L ++I+
Sbjct: 1148 RCEDLEKQNRLLHDQIE 1164
Score = 40.0 bits (92), Expect = 0.004
Identities = 87/385 (22%), Positives = 155/385 (40%), Gaps = 61/385 (15%)
Query: 33 RSERLVAESQRLVDEIEKTTRK---------------SQSDVNKKLEQRLEEVQFWKKEL 77
R E L +++ L D+IEK + K S S+ K EQ LE ++F ++E
Sbjct: 1148 RCEDLEKQNRLLHDQIEKLSDKVVASVKEGVQGPLNVSLSEEGKSQEQILEILRFIRREK 1207
Query: 78 DDKLEQLVNVTDDLLIYKIRLEKALETLKEPLHITETCLAYREKRIGIDLVHDTVEHELI 137
+ + + L Y+ R+E L+E + ++ A REK + + EL+
Sbjct: 1208 EIAETRFEVAQVESLRYRQRVELLERELQE---LQDSLNAEREK-VQVTAKTMAQHEELM 1263
Query: 138 KEAEIIQGIMALLTRTLEEASEQIRMNRSAKYNLEKDLKD---KFVALTIDDICFSLNNN 194
K+ E + +M E +M R K LE+DL+ K L +D L
Sbjct: 1264 KKTETMNVVM-----------ETNKMLREEKERLEQDLQQMQAKVRKLELD----ILPLQ 1308
Query: 195 SPNIRYSENAVRIEPNSVSLE-DWLDFSSTNVEKADKQRNNS-------LMLKALVDRIL 246
N SE + ++ LE D + + N +Q++ L K + + +
Sbjct: 1309 EANAELSEKSGMLQAEKKLLEEDVKRWKARNQHLVSQQKDPDTEEYRKLLSEKEVHTKRI 1368
Query: 247 SQTANDL-RKQCDVVDTAFKNGLKDTKDARDKLADHLAKVMEEIASQEKNITALEKAILD 305
Q ++ R + ++ + L + ++ L + L KV E + +K++ A K I
Sbjct: 1369 QQLTEEIGRLKAEIARS--NASLTNNQNLIQSLKEDLNKVRTEKETIQKDLDA--KIIDI 1424
Query: 306 QEGPAKVAHTRLETRTHRPNVELCRDVAQYRLMK----------EVQEITHNVARLKETL 355
QE + + R ++ E + Q ++M+ E + LKETL
Sbjct: 1425 QEKVKTITQVKKIGRRYKTQYEELK-AQQDKVMETSAQSSGDHQEQHVSVQEMQELKETL 1483
Query: 356 AQAQAELKGLHRRQLALQEEIQVKE 380
QA+ + K L + LQ+ + KE
Sbjct: 1484 NQAETKSKSLESQVENLQKTLSEKE 1508
Score = 32.3 bits (72), Expect = 0.82
Identities = 63/358 (17%), Positives = 137/358 (38%), Gaps = 50/358 (13%)
Query: 28 DAQRSRSERLVAESQRLVDEIEKTTRKSQSDVNKKLEQRLEEVQFWKKELDDKLEQLVNV 87
+ + S + ++ + E+EK ++ Q D + +E +++ KK L ++
Sbjct: 991 EVRLKESAEFQTQLEKKLMEVEKEKQELQDDKRRAIESMEQQLSELKKTLSSVQNEVQEA 1050
Query: 88 TDDLLIYKIRLEKALETLKEPLHITETCLAYREKRIGIDLVHDTVEHELIKEAEIIQGIM 147
L++A L C + +I ++ + E EL+ A ++ +
Sbjct: 1051 ----------LQRASTALSNEQQARRDC--QEQAKIAVE-AQNKYERELMLHAADVEALQ 1097
Query: 148 ALLTRTLEEASEQIRMNRSAKYNLEKDLKDKFVALTIDDICFSLNNNSPNIRYSENAVR- 206
A A EQ+ S + +LE+ + L + S+ R
Sbjct: 1098 A--------AKEQVSKMASVRQHLEETTQKAESQLLECKASWEERERMLKDEVSKCVCRC 1149
Query: 207 --IEPNSVSLEDWLDFSSTNVEKADKQ-----RNNSLMLKALVDRILSQTANDLRKQCDV 259
+E + L D ++ S V + K+ N SL + + + +R++ ++
Sbjct: 1150 EDLEKQNRLLHDQIEKLSDKVVASVKEGVQGPLNVSLSEEGKSQEQILEILRFIRREKEI 1209
Query: 260 VDTAFKNGLKDTKDARDK---LADHLAKVMEEIASQEKNITALEKAILDQEGPAKVAHTR 316
+T F+ ++ R + L L ++ + + ++ + + K + H
Sbjct: 1210 AETRFEVAQVESLRYRQRVELLERELQELQDSLNAEREKVQVTAKTM--------AQHEE 1261
Query: 317 LETRTHRPNVELCRDVAQYRLMKEVQEITHNVARLKETLAQAQAELKGLHRRQLALQE 374
L +T NV + ++++E +E RL++ L Q QA+++ L L LQE
Sbjct: 1262 LMKKTETMNVVM----ETNKMLREEKE------RLEQDLQQMQAKVRKLELDILPLQE 1309
>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
sapiens]
Length = 1843
Score = 50.4 bits (119), Expect = 3e-06
Identities = 91/444 (20%), Positives = 176/444 (39%), Gaps = 69/444 (15%)
Query: 2 AKLLQPPPKFLPSEWHIANKNQYHRADAQRSRSERLVAESQRLVDEIEKTTRK--SQSDV 59
++L + P K L E + ++ + + + + V E + VD +E K
Sbjct: 440 SELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKILKMEKE 499
Query: 60 NKKLEQRLEEVQFWKKELDDKLEQLVNVTDDLLIYKIRLEKALETLKEPL---------- 109
N++L +++E ++ + L+ N++ DL+ K +LEK +ETL+E
Sbjct: 500 NQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQE 559
Query: 110 --HITETCLAYR-------EKRIGIDLVHDTVEHELIKEAEI----IQGIMALLTRTLE- 155
H+ +T + R E R+ + + HE IKE I+ + + LE
Sbjct: 560 NEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEH 619
Query: 156 --EASEQIRMNRSAKYNLEKD---LKDKFVALTIDDICFSLNNNSPNIRYSENAVRIEPN 210
E E+ + ++LEK+ L+ K L I C + E R
Sbjct: 620 YKEKGERAEELENELHHLEKENELLQKKITNLKI--TCEKIEALEQENSELERENRKLKK 677
Query: 211 SVSLEDWLDFSSTNVEKADKQ--------RNNSLMLKA---------LVDRILSQTANDL 253
++ L F ++EK + Q R N LK L ++ L L
Sbjct: 678 TLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQL 737
Query: 254 RKQCDVVDTAFK--NGLKDTKDARDKLADHLAKVMEEIASQEKNITALEKAILDQEGPAK 311
+K +++ +FK L+ + D L K +E + K I LE + D E
Sbjct: 738 KKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLE---NSNKKIQQLESELQDLE---- 790
Query: 312 VAHTRLETRTHRPNVELCRDVAQYRLMKEVQEITHNVARLKETLAQAQAELKGLHRRQLA 371
+E +T + N+E + + K ++++ L++ +Q + + K L +
Sbjct: 791 -----MENQTLQKNLEELKISS-----KRLEQLEKENKSLEQETSQLEKDKKQLEKENKR 840
Query: 372 LQEEIQVKENTIYIDEVLCMQMRK 395
L+++ ++K+ T+ + V + K
Sbjct: 841 LRQQAEIKDTTLEENNVKIGNLEK 864
Score = 35.8 bits (81), Expect = 0.074
Identities = 70/374 (18%), Positives = 141/374 (37%), Gaps = 57/374 (15%)
Query: 24 YHRADAQRSRSERLVAESQRLVDEIEKTTRKSQSD---VNKKLEQ------RLEEVQFWK 74
Y D + R ++ + S + + ++E + + + + K LE+ RLE+++
Sbjct: 758 YQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKEN 817
Query: 75 KELDDKLEQLVNVTDDLLIYKIRLEKALETLKEPLHITETCLAYREKRIGIDLVHDTVEH 134
K L+ + QL K +LEK + L++ I +T L +IG
Sbjct: 818 KSLEQETSQLEK-------DKKQLEKENKRLRQQAEIKDTTLEENNVKIG---------- 860
Query: 135 ELIKEAEIIQGIMALLTRTLEEASEQIRMNRSAKYNLEKDLKDKFVALTIDDICFSLNNN 194
L KE + + + + + E + N+ D+K V L D + L
Sbjct: 861 NLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATIDIK-TLVTLREDLVSEKLKTQ 919
Query: 195 SPNIRYSENAVRIEPNSVSLEDWLDFSSTNVEKADKQRNNSLMLKALVDRILSQTANDLR 254
N + +E ++ E L D+Q + K L ++ S L
Sbjct: 920 QMNNDLEKLTHELEKIGLNKERLLH---------DEQSTDDSRYKLLESKLESTLKKSLE 970
Query: 255 KQCDVVDTAFKNGLKDTKDARDKLADHLAKVMEEIASQEKNITAL-----EKAILDQEGP 309
+ + + A + L+++ + +L +E+ + +KN AL E+ ++ P
Sbjct: 971 IKEEKI-AALEARLEESTNYNQQL-------RQELKTVKKNYEALKQRQDEERMVQSSPP 1022
Query: 310 AKVAHTRLETRTHRPNVELCR--------DVAQYRLMKEVQEITHNVARLKETLAQAQAE 361
+ E + EL + + L E Q + + +L+ QA+
Sbjct: 1023 ISGEDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQ 1082
Query: 362 LKGLHRRQLALQEE 375
+ L R+ ++LQE+
Sbjct: 1083 ILALQRQTVSLQEQ 1096
Score = 33.1 bits (74), Expect = 0.48
Identities = 61/350 (17%), Positives = 147/350 (42%), Gaps = 65/350 (18%)
Query: 54 KSQSDVNKKLEQRLEEVQFWKKELDDKLEQLVNVTDDLLIYKIRLEKALETLKEPLHITE 113
+S+ ++ +L +++ ++EL++K EQL++ +L +I L++ + L
Sbjct: 244 ESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDAR 303
Query: 114 TCLAYREKRIGIDLVHDTVEHELIKEAEIIQGIMALLTRTLEEASEQIRMNRSAKYNLEK 173
+ YR+ E + ++E + +++ ++ + +++E
Sbjct: 304 SARMYRD------------ELDALREKAV----------RVDKLESEVSRYKERLHDIE- 340
Query: 174 DLKDKFVALTIDDICFSLNNNSPNIRYSENAVRIEPNSVSLEDWLDFSSTNVEKADKQRN 233
F ++++ +N V +E ++ LED L+ + +K +
Sbjct: 341 -----FYKARVEEL------------KEDNQVLLETKTM-LEDQLEGTRARSDKLHELEK 382
Query: 234 NSLMLKALVDRILSQTANDLRKQCDVVDTAFKNGLKDTKDARDKLADHLAKVMEEIASQE 293
+L LKA + + + D +K ++++ + + + L HL +E+I+
Sbjct: 383 ENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMDESL--HLGWELEQISRTS 440
Query: 294 KNITALEKAI--------------LDQEGPAKVAHTRLETRTHRPNVE------LCRDVA 333
+ A +K++ L+ E + + T E RT +VE L +
Sbjct: 441 ELSEAPQKSLGHEVNELTSSRLLKLEMENQS-LTKTVEELRTTVDSVEGNASKILKMEKE 499
Query: 334 QYRLMKEVQEITHNVARLKETLAQAQAELKGLHRRQLALQEEIQ-VKENT 382
RL K+V+ + + + + K++L Q K L + + L++ I+ ++EN+
Sbjct: 500 NQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENS 549
>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
sapiens]
Length = 1870
Score = 50.4 bits (119), Expect = 3e-06
Identities = 91/444 (20%), Positives = 176/444 (39%), Gaps = 69/444 (15%)
Query: 2 AKLLQPPPKFLPSEWHIANKNQYHRADAQRSRSERLVAESQRLVDEIEKTTRK--SQSDV 59
++L + P K L E + ++ + + + + V E + VD +E K
Sbjct: 440 SELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKILKMEKE 499
Query: 60 NKKLEQRLEEVQFWKKELDDKLEQLVNVTDDLLIYKIRLEKALETLKEPL---------- 109
N++L +++E ++ + L+ N++ DL+ K +LEK +ETL+E
Sbjct: 500 NQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQE 559
Query: 110 --HITETCLAYR-------EKRIGIDLVHDTVEHELIKEAEI----IQGIMALLTRTLE- 155
H+ +T + R E R+ + + HE IKE I+ + + LE
Sbjct: 560 NEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEH 619
Query: 156 --EASEQIRMNRSAKYNLEKD---LKDKFVALTIDDICFSLNNNSPNIRYSENAVRIEPN 210
E E+ + ++LEK+ L+ K L I C + E R
Sbjct: 620 YKEKGERAEELENELHHLEKENELLQKKITNLKI--TCEKIEALEQENSELERENRKLKK 677
Query: 211 SVSLEDWLDFSSTNVEKADKQ--------RNNSLMLKA---------LVDRILSQTANDL 253
++ L F ++EK + Q R N LK L ++ L L
Sbjct: 678 TLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQL 737
Query: 254 RKQCDVVDTAFK--NGLKDTKDARDKLADHLAKVMEEIASQEKNITALEKAILDQEGPAK 311
+K +++ +FK L+ + D L K +E + K I LE + D E
Sbjct: 738 KKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLE---NSNKKIQQLESELQDLE---- 790
Query: 312 VAHTRLETRTHRPNVELCRDVAQYRLMKEVQEITHNVARLKETLAQAQAELKGLHRRQLA 371
+E +T + N+E + + K ++++ L++ +Q + + K L +
Sbjct: 791 -----MENQTLQKNLEELKISS-----KRLEQLEKENKSLEQETSQLEKDKKQLEKENKR 840
Query: 372 LQEEIQVKENTIYIDEVLCMQMRK 395
L+++ ++K+ T+ + V + K
Sbjct: 841 LRQQAEIKDTTLEENNVKIGNLEK 864
Score = 33.1 bits (74), Expect = 0.48
Identities = 61/350 (17%), Positives = 147/350 (42%), Gaps = 65/350 (18%)
Query: 54 KSQSDVNKKLEQRLEEVQFWKKELDDKLEQLVNVTDDLLIYKIRLEKALETLKEPLHITE 113
+S+ ++ +L +++ ++EL++K EQL++ +L +I L++ + L
Sbjct: 244 ESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDAR 303
Query: 114 TCLAYREKRIGIDLVHDTVEHELIKEAEIIQGIMALLTRTLEEASEQIRMNRSAKYNLEK 173
+ YR+ E + ++E + +++ ++ + +++E
Sbjct: 304 SARMYRD------------ELDALREKAV----------RVDKLESEVSRYKERLHDIE- 340
Query: 174 DLKDKFVALTIDDICFSLNNNSPNIRYSENAVRIEPNSVSLEDWLDFSSTNVEKADKQRN 233
F ++++ +N V +E ++ LED L+ + +K +
Sbjct: 341 -----FYKARVEEL------------KEDNQVLLETKTM-LEDQLEGTRARSDKLHELEK 382
Query: 234 NSLMLKALVDRILSQTANDLRKQCDVVDTAFKNGLKDTKDARDKLADHLAKVMEEIASQE 293
+L LKA + + + D +K ++++ + + + L HL +E+I+
Sbjct: 383 ENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMDESL--HLGWELEQISRTS 440
Query: 294 KNITALEKAI--------------LDQEGPAKVAHTRLETRTHRPNVE------LCRDVA 333
+ A +K++ L+ E + + T E RT +VE L +
Sbjct: 441 ELSEAPQKSLGHEVNELTSSRLLKLEMENQS-LTKTVEELRTTVDSVEGNASKILKMEKE 499
Query: 334 QYRLMKEVQEITHNVARLKETLAQAQAELKGLHRRQLALQEEIQ-VKENT 382
RL K+V+ + + + + K++L Q K L + + L++ I+ ++EN+
Sbjct: 500 NQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENS 549
Score = 32.3 bits (72), Expect = 0.82
Identities = 72/376 (19%), Positives = 146/376 (38%), Gaps = 62/376 (16%)
Query: 24 YHRADAQRSRSERLVAESQRLVDEIEKTTRKSQSD---VNKKLEQ------RLEEVQFWK 74
Y D + R ++ + S + + ++E + + + + K LE+ RLE+++
Sbjct: 758 YQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKEN 817
Query: 75 KELDDKLEQLVNVTDDLLIYKIRLEKALETLKEPLHITETCLAYREKRIGIDLVHDTVEH 134
K L+ + QL K +LEK + L++ I +T L +IG
Sbjct: 818 KSLEQETSQLEK-------DKKQLEKENKRLRQQAEIKDTTLEENNVKIG---------- 860
Query: 135 ELIKEAEIIQGIMALLTRTLEEASEQIRMNRSAKYNLEKDLKDKFVALTIDDICFSLNNN 194
L KE + + + + + E + N+ D+K V L D + L
Sbjct: 861 NLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATIDIK-TLVTLREDLVSEKLKTQ 919
Query: 195 SPNIRYSENAVRIEPNSVSLEDWL-DFSSTNVEKADKQRNNSLMLKALVDRILSQTANDL 253
N + +E ++ E L D ST+ D+ + L++ L T L
Sbjct: 920 QMNNDLEKLTHELEKIGLNKERLLHDEQSTD----DRYK--------LLESKLEST---L 964
Query: 254 RKQCDVVDTAFKNGLKDTKDAR-DKLADHLAKVMEEIASQEKNITAL-----EKAILDQE 307
+K ++ + +AR ++ ++ ++ +E+ + +KN AL E+ ++
Sbjct: 965 KKSLEIKEEKIA-----ALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSS 1019
Query: 308 GPAKVAHTRLETRTHRPNVELCR--------DVAQYRLMKEVQEITHNVARLKETLAQAQ 359
P + E + EL + + L E Q + + +L+ Q
Sbjct: 1020 PPISGEDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQ 1079
Query: 360 AELKGLHRRQLALQEE 375
A++ L R+ ++LQE+
Sbjct: 1080 AQILALQRQTVSLQEQ 1095
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 50.1 bits (118), Expect = 4e-06
Identities = 79/382 (20%), Positives = 166/382 (43%), Gaps = 50/382 (13%)
Query: 26 RADAQRSRSERLVAESQRLVDEIEKTTRKSQSDVNKKLEQRLEEVQFWKKELDDKLEQLV 85
R A++ E + + + V+E E+ + Q++ KK++Q ++E L+++LE+
Sbjct: 905 RLTAKKQELEEICHDLEARVEEEEERCQHLQAE-KKKMQQNIQE-------LEEQLEEEE 956
Query: 86 NVTDDLLIYKIRLEKALETLKEPLHITE--TCLAYREKRIGIDLVHDTVEHELIKEAEII 143
+ L + K+ E L+ L+E I E C +EK++ D + + + L +E E
Sbjct: 957 SARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTN-LTEEEEKS 1015
Query: 144 QGIMALLTR---TLEEASEQIRMNRSAKYNLEKDLKDKFVALTIDDICFSLNNNSPNIRY 200
+ + L + + + E++R + LEK + ++ L++ ++
Sbjct: 1016 KSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRR------KLEGDSTDLSDQIAELQ- 1068
Query: 201 SENAVRIEPNSVSLEDWLDFSSTNVEKADKQRNNSLMLKALVDRILSQTANDLRKQCDVV 260
++ E+ L + VE+ Q+N +L ++ +S+ DL +
Sbjct: 1069 -AQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASR 1127
Query: 261 DTAFKNGLKDTKDARDKLADHLAKVMEEIASQ-------EKNITALEKAILDQEGPAKVA 313
+ A K +D + + L L ++ A+Q E+ + L+K L++E A
Sbjct: 1128 NKAEKQ-KRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKT-LEEEAKTHEA 1185
Query: 314 HTRLETRTHRPNVELCRDVAQYRLMKEVQEITHNVARLKETLAQAQAEL----------K 363
+ + H VE ++A+ +++ + + N+ + K+TL + EL K
Sbjct: 1186 QIQEMRQKHSQAVE---ELAEQ--LEQTKRVKANLEKAKQTLENERGELANEVKVLLQGK 1240
Query: 364 G--LHRRQL--ALQEEIQVKEN 381
G H+R+ A +E+QVK N
Sbjct: 1241 GDSEHKRKKVEAQLQELQVKFN 1262
Score = 48.9 bits (115), Expect = 8e-06
Identities = 60/325 (18%), Positives = 138/325 (42%), Gaps = 44/325 (13%)
Query: 64 EQRLEEVQFWKKELDDKLEQLVNVTDDLLIYKIRLEKALETLKEPLHITETCLAYREKRI 123
E+ L +V+ + +++L ++ + L+ K++L++ L+ TE C E R
Sbjct: 851 EEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAE------TELCAEAEELRA 904
Query: 124 GI--------DLVHDTVEHELIKEAEIIQGIMA---LLTRTLEEASEQIRMNRSAKYNLE 172
+ ++ HD +E + +E E Q + A + + ++E EQ+ SA+ L+
Sbjct: 905 RLTAKKQELEEICHD-LEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQ 963
Query: 173 KDLKDKFVALTIDDICFSLNNNSPNIRYSENAVRIEPNSVSLEDWLDFSSTNVEKADKQR 232
+ +T + L I + ++ LED + +TN+ + +++
Sbjct: 964 LE------KVTTEAKLKKLEEEQ--IILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKS 1015
Query: 233 NNSLMLKALVDRILSQTANDLRKQCDVVDTAFKNGLKDTKDARDKLADHLAKVMEEIASQ 292
+ LK + +++ LR++ + ++ + R KL + ++IA
Sbjct: 1016 KSLAKLKNKHEAMITDLEERLRRE--------EKQRQELEKTRRKLEGDSTDLSDQIAEL 1067
Query: 293 EKNITALEKAILDQEGPAKVAHTRLETRTHRPNVELCRDVAQYRLMKEVQEITHNVARLK 352
+ I L+ + +E + A R+E + N+ L K+++E+ ++ L+
Sbjct: 1068 QAQIAELKMQLAKKEEELQAALARVEEEAAQKNMAL----------KKIRELESQISELQ 1117
Query: 353 ETLAQAQAELKGLHRRQLALQEEIQ 377
E L +A +++ L EE++
Sbjct: 1118 EDLESERASRNKAEKQKRDLGEELE 1142
Score = 37.4 bits (85), Expect = 0.025
Identities = 64/372 (17%), Positives = 145/372 (38%), Gaps = 60/372 (16%)
Query: 28 DAQRSRSERLVAESQRLVDEIEKTTRKSQSDVNKK------LEQRLEEVQFWKKELDDKL 81
+ ++ + ++L+AE + + + + +++++ +K L + LEE K EL+
Sbjct: 1440 EKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLN 1499
Query: 82 EQLVNVTDDLLIYKIRLEKALETLKEPLHITETCLAYREKRIGIDLVHDTVEHELIKEAE 141
+Q +DL+ K + K++ HEL K
Sbjct: 1500 KQFRTEMEDLMSSKDDVGKSV-------------------------------HELEKSKR 1528
Query: 142 IIQGIMALLTRTLEEASEQIRMNRSAKYNLEKDLKDKFVALTIDDICFSLNNNSPNIRYS 201
++ + + LEE ++++ AK LE +L+ D + +
Sbjct: 1529 ALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERD---LQGRDEQSEEKKK 1585
Query: 202 ENAVRIEPNSVSLEDWLDFSSTNVEKADKQRNNSLMLKALVDRILSQTANDLRKQCDVVD 261
+ ++ LED S V K + L+A +D ++ ++ KQ +
Sbjct: 1586 QLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDS-ANKNRDEAIKQLRKLQ 1644
Query: 262 TAFKNGLKDTKDARDKLADHLAKVMEEIASQEKNITALEKAILDQEGPAKVAHTRLETRT 321
K+ +++ D R + LA+ E EK + ++E ++ + A R + +
Sbjct: 1645 AQMKDCMRELDDTRASREEILAQAKE----NEKKLKSMEAEMIQLQEELAAAE-RAKRQA 1699
Query: 322 HRPNVELCRDVAQYR-----LMKEVQEITHNVARLKETLAQAQAELKGLHRRQLALQEEI 376
+ EL ++A ++E + + +A+L+E L + Q + ++ R
Sbjct: 1700 QQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDR-------- 1751
Query: 377 QVKENTIYIDEV 388
+K+ + ID++
Sbjct: 1752 -LKKANLQIDQI 1762
Score = 32.3 bits (72), Expect = 0.82
Identities = 69/364 (18%), Positives = 140/364 (38%), Gaps = 56/364 (15%)
Query: 27 ADAQRSRSERLVAESQRLVDEIEKTTRKSQSDVNKKLEQRLEEVQFWKKELDDKLEQLVN 86
++ +R + E + E Q +E E+ R +D KL+ L+ V + D K +L
Sbjct: 1243 SEHKRKKVEAQLQELQVKFNEGERV-RTELADKVTKLQVELDNVTGLLSQSDSKSSKL-- 1299
Query: 87 VTDDLLIYKIRLEKALETLKEPLHITETCLAYREKRIGIDL--------VHDTVEHELIK 138
T D + +L+ E L+E + + L+ + K++ + + +H L K
Sbjct: 1300 -TKDFSALESQLQDTQELLQEE-NRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEK 1357
Query: 139 EAEIIQGIMALLTRTLEEASEQIRMNRSAKYNLEKDLKDKFVALTIDDICFSLNNNSPNI 198
+ + +A + + +E++ + K L+KDL+ S +
Sbjct: 1358 QIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEG-----------LSQRHEEKVA 1406
Query: 199 RYSENAVRIEPNSVSLEDWLDFSSTNVEKADKQRNNSLMLKALVDRILSQTANDLRKQCD 258
Y ++E L+ LD +++ + N + D++L++ K +
Sbjct: 1407 AYD----KLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAE 1462
Query: 259 VVDTAFKNGLKDTKDARDK--LADHLAKVMEEIASQEKNITALEKAILDQEGPAKVAHTR 316
D A +AR+K A LA+ +EE Q+ + L K
Sbjct: 1463 ERDRA-------EAEAREKETKALSLARALEEAMEQKAELERLNK--------------- 1500
Query: 317 LETRTHRPNVELCRD---VAQYRLMKEVQEITHNVARLKETLAQAQAELKGLHRRQLALQ 373
+ RT ++ +D + + L K + + V +K L + + EL+ +L L+
Sbjct: 1501 -QFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLE 1559
Query: 374 EEIQ 377
+Q
Sbjct: 1560 VNLQ 1563
>gi|46049114 M-phase phosphoprotein 1 [Homo sapiens]
Length = 1780
Score = 49.7 bits (117), Expect = 5e-06
Identities = 73/374 (19%), Positives = 162/374 (43%), Gaps = 58/374 (15%)
Query: 19 ANKNQYHRADAQRSRSERLVAESQRLVDEIEKTTRKSQSDVNKKLEQRLEEVQFWKKELD 78
A+ + H+ + + E+L AE + DE + K + + L+++ +Q K+EL
Sbjct: 1030 ASSKKSHQIEELEQQIEKLQAEVKGYKDENNRLKEKEHKNQDDLLKEKETLIQQLKEELQ 1089
Query: 79 DKLEQLVNVTDDLLIYKIRLEKALETLKEPLHITETCLAYREKRIGIDLVHDTVEHELIK 138
+K NVT D ++++ +E + +T+ Y+ K ++ + +T + E
Sbjct: 1090 EK-----NVTLD-----VQIQHVVEGKRALSELTQGVTCYKAKIKELETILETQKVECSH 1139
Query: 139 EAEIIQGIMALLTRTLEEASEQIRMNRSAKYNLEKDLKDKFVALTIDDICFSLNNNSPNI 198
A++ Q I LE+ S +++ R+ K ++ L+D N N+
Sbjct: 1140 SAKLEQDI-------LEKESIILKLERNLK-EFQEHLQDSV-----------KNTKDLNV 1180
Query: 199 RYSENAVRIEPNSVSLEDWLDFSSTNVEKADKQRNNSLMLKALVDRILSQTANDLRKQCD 258
+ + I + +L+D E+ + R + LK + ++T N
Sbjct: 1181 KELKLKEEITQLTNNLQDMKHLLQLKEEEEETNRQETEKLKEELSASSARTQN------- 1233
Query: 259 VVDTAFKNGLKDTKDARDKLADHLAKVMEEIASQEKNITALEKAILDQEGPAKVAHTRLE 318
+ + +D D ++KL D ++I +K ++ + D++ ++ LE
Sbjct: 1234 -LKADLQRKEEDYADLKEKLTD----AKKQIKQVQKEVSVMR----DEDKLLRIKINELE 1284
Query: 319 TRTHRPNVELCRDVAQYRLMKEVQEITHNVARLKETLAQAQAELKGLH---------RRQ 369
+ ++ + EL D+ Q R +++++E +N +++E + Q + K L+ R
Sbjct: 1285 KKKNQCSQEL--DMKQ-RTIQQLKEQLNN-QKVEEAIQQYERACKDLNVKEKIIEDMRMT 1340
Query: 370 LALQEEIQVKENTI 383
L QE+ QV+++ +
Sbjct: 1341 LEEQEQTQVEQDQV 1354
Score = 32.0 bits (71), Expect = 1.1
Identities = 71/360 (19%), Positives = 147/360 (40%), Gaps = 58/360 (16%)
Query: 30 QRSRSERLVAESQRLVDEIEKTTRKSQSDVN--KKLEQRLEEVQFWKKELDDKLEQLVNV 87
Q+S+++ + +L +EIE TR ++V+ K + +++E++ D + Q+ N+
Sbjct: 910 QKSKNQEQEEKIMKLSNEIETATRSITNNVSQIKLMHTKIDELRTL-----DSVSQISNI 964
Query: 88 TDDLLIYKIRLEKALETLKEPLHITETCLAYREKRIGID-LVHDTVEHELIKEAEIIQGI 146
DLL + L E ++ T L +G D LV V+ I+E
Sbjct: 965 --DLLNL-----RDLSNGSEEDNLPNTQL----DLLGNDYLVSKQVKEYRIQEPNRENSF 1013
Query: 147 MALLTRTLEEASEQIRMNRSAKYNLEKDLKDKFVALTIDDICFSLNNNSPNIRYSENAVR 206
+ + EE E ++ + + +E E +
Sbjct: 1014 HSSIEAIWEECKEIVKASSKKSHQIE-----------------------------ELEQQ 1044
Query: 207 IEPNSVSLEDWLDFSSTNVEKADKQRNNSLMLKALVDRILSQTANDLRKQCDVVDTAFKN 266
IE ++ + D ++ EK K +++ L K + + L + + DV
Sbjct: 1045 IEKLQAEVKGYKDENNRLKEKEHKNQDDLLKEKETLIQQLKEELQEKNVTLDVQIQHVVE 1104
Query: 267 GLKDTKDARDKLADHLAKV--MEEIASQEK----NITALEKAILDQEG-PAKVAHTRLET 319
G + + + + AK+ +E I +K + LE+ IL++E K+ E
Sbjct: 1105 GKRALSELTQGVTCYKAKIKELETILETQKVECSHSAKLEQDILEKESIILKLERNLKEF 1164
Query: 320 RTH-RPNVELCRD--VAQYRLMKEVQEITHNVARLKETLAQAQAELKGLHRRQLALQEEI 376
+ H + +V+ +D V + +L +E+ ++T+N+ +K L + E + + L+EE+
Sbjct: 1165 QEHLQDSVKNTKDLNVKELKLKEEITQLTNNLQDMKHLLQLKEEEEETNRQETEKLKEEL 1224
>gi|38044112 restin isoform b [Homo sapiens]
Length = 1392
Score = 49.3 bits (116), Expect = 6e-06
Identities = 78/390 (20%), Positives = 150/390 (38%), Gaps = 36/390 (9%)
Query: 26 RADAQRSRSERLVAESQRLVDEIEKTTRKSQ-SDVNKKLEQRLEEVQFWKKELDDKLEQL 84
+++ ++ R + AE Q EIEK S+ S + ++L+ R + KL L
Sbjct: 741 KSEMKKLRQQLEAAEKQIKHLEIEKNAESSKASSITRELQGR-----------ELKLTNL 789
Query: 85 VNVTDDLLIYKIRLEKALETLKEPLHIT--ETCLAYREKRIGIDLVHDTVE--HELIKEA 140
++ K LEK L+ LKE E R + ++ +H E + L +
Sbjct: 790 QENLSEVSQVKETLEKELQILKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDL 849
Query: 141 EIIQGIMALLTRTLEEASEQIRMNRSAKYNLEKDLKDKFVALTIDDICFSLNNNSPNIRY 200
E ++ +A + E E+ AK LE D+ + + D L + +R
Sbjct: 850 EKLRENLADMEAKFREKDEREEQLIKAKEKLENDIAE--IMKMSGDNSSQLTKMNDELRL 907
Query: 201 SENAVR-IEPNSVSLEDWLDFSSTNVE----KADKQRNNSLMLKALVDRILSQTANDLRK 255
E V ++ + F ++E KA++ + + + L + +DL K
Sbjct: 908 KERDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLEK 967
Query: 256 -------QCDVVDTAFKNGLKDTKDARDKLADHLAKVMEEIASQEKNITALEKAILDQ-E 307
QC + ++ +TK +++ +L K + + + K +L + E
Sbjct: 968 KMETSHNQCQELKARYERATSETKTKHEEILQNLQKTLLDTEDKLKGAREENSGLLQELE 1027
Query: 308 GPAKVAHTRLETRTHRPNVELCRDVAQYRLMKEVQEITHNVARLKETLAQAQAELKGLHR 367
K A +T +++ ++ KE E ++ K+T A+ Q EL L
Sbjct: 1028 ELRKQADKAKAAQTAEDAMQIME-----QMTKEKTETLASLEDTKQTNAKLQNELDTLKE 1082
Query: 368 RQLALQEEIQVKENTIYIDEVLCMQMRKSI 397
L EE+ + + ++ + RK I
Sbjct: 1083 NNLKNVEELNKSKELLTVENQKMEEFRKEI 1112
Score = 42.7 bits (99), Expect = 6e-04
Identities = 99/460 (21%), Positives = 185/460 (40%), Gaps = 89/460 (19%)
Query: 10 KFLPSEWHIANKNQYHRADAQRSRSERLVAESQRLVDEIEKTT--RKSQSDVNKKLEQRL 67
K L + A K H + + S + + ++ L K T +++ S+V++ E
Sbjct: 745 KKLRQQLEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTNLQENLSEVSQVKETLE 804
Query: 68 EEVQFWKKELDDKLEQLVNVTDDL--LIYKIR--------LEKALETLKEPLHITETCLA 117
+E+Q K++ + E+ V+V + + K+ L LE L+E L E
Sbjct: 805 KELQILKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADMEA--K 862
Query: 118 YREKRIGIDLVHDTVEHELIKEAEIIQGIMALLTRTLEEASEQI-RMNRSAKYNLEKDLK 176
+REK D E +LIK E ++ +A + + + S Q+ +MN + E+D++
Sbjct: 863 FREK--------DEREEQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLK-ERDVE 913
Query: 177 D------------KFVALTIDDICFSLNNNSPNIRYSENAVRIEPNSVSLEDWLDFSSTN 224
+ F+ +I+D+ + E A + E LE L S
Sbjct: 914 ELQLKLTKANENASFLQKSIEDMTVKAEQSQ-----QEAAKKHEEEKKELERKL---SDL 965
Query: 225 VEKADKQRNNSLMLKALVDRILSQTANDLRKQCDVVDTAFKNGLKDTKD----ARDKLAD 280
+K + N LKA +R S+T K +++ K L DT+D AR++ +
Sbjct: 966 EKKMETSHNQCQELKARYERATSETKT---KHEEILQNLQKT-LLDTEDKLKGAREENSG 1021
Query: 281 HLAKVMEEIASQEKNITALEKA-----ILDQEGPAKVAHTRLETRTHRPNVEL------- 328
L + +EE+ Q A + A I++Q K T + N +L
Sbjct: 1022 -LLQELEELRKQADKAKAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQNELDTL 1080
Query: 329 ----CRDVAQYRLMKEV--------QEITHNVARLKETLAQAQAELKGLHRRQLALQEEI 376
++V + KE+ +E + LK+ AQ +L L + L EE+
Sbjct: 1081 KENNLKNVEELNKSKELLTVENQKMEEFRKEIETLKQAAAQKSQQLSALQEENVKLAEEL 1140
Query: 377 ------------QVKENTIYIDEVLCMQMRKSIPLRDGED 404
+E ++ +++L M+ R+S ++D ++
Sbjct: 1141 GRSRDEVTSHQKLEEERSVLNNQLLEMKKRESKFIKDADE 1180
>gi|4506751 restin isoform a [Homo sapiens]
Length = 1427
Score = 49.3 bits (116), Expect = 6e-06
Identities = 78/390 (20%), Positives = 150/390 (38%), Gaps = 36/390 (9%)
Query: 26 RADAQRSRSERLVAESQRLVDEIEKTTRKSQ-SDVNKKLEQRLEEVQFWKKELDDKLEQL 84
+++ ++ R + AE Q EIEK S+ S + ++L+ R + KL L
Sbjct: 776 KSEMKKLRQQLEAAEKQIKHLEIEKNAESSKASSITRELQGR-----------ELKLTNL 824
Query: 85 VNVTDDLLIYKIRLEKALETLKEPLHIT--ETCLAYREKRIGIDLVHDTVE--HELIKEA 140
++ K LEK L+ LKE E R + ++ +H E + L +
Sbjct: 825 QENLSEVSQVKETLEKELQILKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDL 884
Query: 141 EIIQGIMALLTRTLEEASEQIRMNRSAKYNLEKDLKDKFVALTIDDICFSLNNNSPNIRY 200
E ++ +A + E E+ AK LE D+ + + D L + +R
Sbjct: 885 EKLRENLADMEAKFREKDEREEQLIKAKEKLENDIAE--IMKMSGDNSSQLTKMNDELRL 942
Query: 201 SENAVR-IEPNSVSLEDWLDFSSTNVE----KADKQRNNSLMLKALVDRILSQTANDLRK 255
E V ++ + F ++E KA++ + + + L + +DL K
Sbjct: 943 KERDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLEK 1002
Query: 256 -------QCDVVDTAFKNGLKDTKDARDKLADHLAKVMEEIASQEKNITALEKAILDQ-E 307
QC + ++ +TK +++ +L K + + + K +L + E
Sbjct: 1003 KMETSHNQCQELKARYERATSETKTKHEEILQNLQKTLLDTEDKLKGAREENSGLLQELE 1062
Query: 308 GPAKVAHTRLETRTHRPNVELCRDVAQYRLMKEVQEITHNVARLKETLAQAQAELKGLHR 367
K A +T +++ ++ KE E ++ K+T A+ Q EL L
Sbjct: 1063 ELRKQADKAKAAQTAEDAMQIME-----QMTKEKTETLASLEDTKQTNAKLQNELDTLKE 1117
Query: 368 RQLALQEEIQVKENTIYIDEVLCMQMRKSI 397
L EE+ + + ++ + RK I
Sbjct: 1118 NNLKNVEELNKSKELLTVENQKMEEFRKEI 1147
Score = 42.7 bits (99), Expect = 6e-04
Identities = 99/460 (21%), Positives = 185/460 (40%), Gaps = 89/460 (19%)
Query: 10 KFLPSEWHIANKNQYHRADAQRSRSERLVAESQRLVDEIEKTT--RKSQSDVNKKLEQRL 67
K L + A K H + + S + + ++ L K T +++ S+V++ E
Sbjct: 780 KKLRQQLEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTNLQENLSEVSQVKETLE 839
Query: 68 EEVQFWKKELDDKLEQLVNVTDDL--LIYKIR--------LEKALETLKEPLHITETCLA 117
+E+Q K++ + E+ V+V + + K+ L LE L+E L E
Sbjct: 840 KELQILKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADMEA--K 897
Query: 118 YREKRIGIDLVHDTVEHELIKEAEIIQGIMALLTRTLEEASEQI-RMNRSAKYNLEKDLK 176
+REK D E +LIK E ++ +A + + + S Q+ +MN + E+D++
Sbjct: 898 FREK--------DEREEQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLK-ERDVE 948
Query: 177 D------------KFVALTIDDICFSLNNNSPNIRYSENAVRIEPNSVSLEDWLDFSSTN 224
+ F+ +I+D+ + E A + E LE L S
Sbjct: 949 ELQLKLTKANENASFLQKSIEDMTVKAEQSQ-----QEAAKKHEEEKKELERKL---SDL 1000
Query: 225 VEKADKQRNNSLMLKALVDRILSQTANDLRKQCDVVDTAFKNGLKDTKD----ARDKLAD 280
+K + N LKA +R S+T K +++ K L DT+D AR++ +
Sbjct: 1001 EKKMETSHNQCQELKARYERATSETKT---KHEEILQNLQKT-LLDTEDKLKGAREENSG 1056
Query: 281 HLAKVMEEIASQEKNITALEKA-----ILDQEGPAKVAHTRLETRTHRPNVEL------- 328
L + +EE+ Q A + A I++Q K T + N +L
Sbjct: 1057 -LLQELEELRKQADKAKAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQNELDTL 1115
Query: 329 ----CRDVAQYRLMKEV--------QEITHNVARLKETLAQAQAELKGLHRRQLALQEEI 376
++V + KE+ +E + LK+ AQ +L L + L EE+
Sbjct: 1116 KENNLKNVEELNKSKELLTVENQKMEEFRKEIETLKQAAAQKSQQLSALQEENVKLAEEL 1175
Query: 377 ------------QVKENTIYIDEVLCMQMRKSIPLRDGED 404
+E ++ +++L M+ R+S ++D ++
Sbjct: 1176 GRSRDEVTSHQKLEEERSVLNNQLLEMKKRESKFIKDADE 1215
>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
transmembrane signal), 1 [Homo sapiens]
Length = 3259
Score = 48.9 bits (115), Expect = 8e-06
Identities = 85/378 (22%), Positives = 165/378 (43%), Gaps = 51/378 (13%)
Query: 28 DAQRSRSERLVAESQRLVDEIE--KTTRKSQ-----SDVNKKLEQRLEEVQFWKKELDDK 80
D +S + R++A++ +L E++ K + KSQ D+ ++LEQ E+ KK + +K
Sbjct: 2085 DDTQSEAARVLADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKNMQEK 2144
Query: 81 LEQLVNVTDDLLIYKIRLEKALETLKEPLHITETCLAYREKRIGIDLVHDTVEHELIKEA 140
L D L K+ LE+ + ++ L+ + + ++ + D+ +L
Sbjct: 2145 L-------DALRREKVHLEETIGEIQVTLNKKDKEVQQLQENL------DSTVTQLAAFT 2191
Query: 141 EIIQGIMALLTRTLEEASEQIRMNRSAKYNLEKDLKDKFVALTIDDICFSLNN--NSPNI 198
+ + + R ++EA + R A + E++++ K +D C L + +I
Sbjct: 2192 KSMSSLQDDRDRVIDEAKKWERKFSDAIQSKEEEIRLK------EDNCSVLKDQLRQMSI 2245
Query: 199 RYSENAVRIEPNSVSLEDWLDFSSTNVEKADK-----QRNNSLMLKALVD--RILSQTAN 251
E + I + W + T V+ K Q N +L L + + + N
Sbjct: 2246 HMEELKINISRLEHDKQIWESKAQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHSSQN 2305
Query: 252 DLRKQCDVVDTAFKNGLKDTKDARDKLADHLAKVMEEIASQEKNITALEKAILDQEGPAK 311
+L K ++ LK KD L++ L K E+ + E I E I + +K
Sbjct: 2306 ELAK--------LESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQN----SK 2353
Query: 312 VAHTRLETRTHRPNVELCRDVAQYRLMKEVQEITHNVARLKETLAQAQAELKGLHRRQLA 371
++ +LET + + EL + + MKE Q+I ++ +E + A AEL+ H +++
Sbjct: 2354 FSYEQLETDL-QASRELTSRLHEEINMKE-QKIISLLSGKEEAIQVAIAELRQQHDKEIK 2411
Query: 372 LQEEI--QVKENTIYIDE 387
E + Q +E I ++E
Sbjct: 2412 ELENLLSQEEEENIVLEE 2429
Score = 40.0 bits (92), Expect = 0.004
Identities = 84/389 (21%), Positives = 154/389 (39%), Gaps = 52/389 (13%)
Query: 12 LPSEWHIANKNQYHRADAQRSRSERLVAESQRLVDEIEKTTRKSQSDVNKKLEQRLEEVQ 71
L E H + +++ Q ERL A +++LV E++ R Q DV +L+Q+ E +Q
Sbjct: 30 LDPELHQESDMEFNNT-TQEDVQERL-AYAEQLVVELKDIIR--QKDV--QLQQKDEALQ 83
Query: 72 FWKKELDDKLEQLVNVTDDLLIYKIRLEKALETLK---------EPLHITETCLAYREKR 122
+K D+K+++L L L K +E +K EP E + +
Sbjct: 84 EERKAADNKIKKLKLHAKAKLT---SLNKYIEEMKAQGGTVLPTEP-QSEEQLSKHDKSS 139
Query: 123 IGIDLVHDTVEHELIKEAEIIQGIMALLTRTLEE--ASEQIRMNRSAKYNLEKDLKDKFV 180
++ + ++H+L ++ E+I + A LT+ E A M + K++F+
Sbjct: 140 TEEEMEIEKIKHKLQEKEELISTLQAQLTQAQAEQPAQSSTEMEEFVMMKQQLQEKEEFI 199
Query: 181 ALTIDDICFSLNNNSPNIRYSENAVRIEPNSVSLEDWLDFSSTNVEKADKQRNNSLMLKA 240
+ + + + E R E ED L V +AD + L+
Sbjct: 200 STLQAQLSQTQAEQAAQQVVREKDARFETQVRLHEDEL---LQLVTQADVETEMQQKLRV 256
Query: 241 LVDRILSQTANDLRKQCDVVDTAFKNGLKDTKDARDKLADHLAKVMEEIASQEKNITALE 300
L R L + L + VVD + +E+ + E+ L
Sbjct: 257 L-QRKLEEHEESLVGRAQVVDL----------------------LQQELTAAEQRNQILS 293
Query: 301 KAILDQEGPAKVAHTRLETRTHRPNVELCR---DVAQYRL-MKEVQEITHNVARLKETLA 356
+ + E +ET + L + +VA+ +L +QE H++ E
Sbjct: 294 QQLQQMEAEHNTLRNTVETEREESKILLEKMELEVAERKLSFHNLQEEMHHLLEQFEQAG 353
Query: 357 QAQAELKGLHRRQLALQEEIQVKENTIYI 385
QAQAEL+ + L + + +++E T +I
Sbjct: 354 QAQAELESRY-SALEQKHKAEMEEKTSHI 381
Score = 38.5 bits (88), Expect = 0.011
Identities = 71/409 (17%), Positives = 156/409 (38%), Gaps = 70/409 (17%)
Query: 4 LLQPPPKFLPSEWHIANKNQYHRADAQRSRSERLVAESQRLVDEIEKTTRKSQSDVNKKL 63
++ PP W + + + ++ + ++ + E+ I K ++ + + ++L
Sbjct: 1146 VISPPCTGSSEHWKPELEEKILALEKEKEQLQKKLQEALTSRKAILKKAQEKERHLREEL 1205
Query: 64 EQRLEEVQFWKKELDDKLEQLVNVTDDLLIYKIRLEKALETLKEPLHITETCLAYREKRI 123
+Q+ ++ +++ D++ ++ N+ D L +I++ ++++ E+C +
Sbjct: 1206 KQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQVRESIDGKLPSTDQQESCSS------ 1259
Query: 124 GIDLVHDTVEHELIKEAEIIQGIMALLTRTLEEASEQIRMNRSAKYNLEKDLKDKFVALT 183
T LEE + + LE +L + + +
Sbjct: 1260 ---------------------------TPGLEEPLFKATEQHHTQPVLESNLCPDWPSHS 1292
Query: 184 IDDICFSLNNNSPNIRYSENAVRIEPNSVSLEDWLDFSSTNVEKADK-----QRNNSLML 238
D +L + + IE V LE L SST E K Q +
Sbjct: 1293 ED--ASALQGGTSVAQIKAQLKEIEAEKVELE--LKVSSTTSELTKKSEEVFQLQEQINK 1348
Query: 239 KALVDRILSQTANDLRKQCDVVDTAFKN------GLKDTKDARDKLADHLAKVME----- 287
+ L L +++ + + ++ GL+ ++ + KL D L K++
Sbjct: 1349 QGLEIESLKTVSHEAEVHAESLQQKLESSQLQIAGLEHLRELQPKL-DELQKLISKKEED 1407
Query: 288 ------EIASQEKNITALEKAILDQEGPAKVAHTRLE-------TRTHRPNVELCRDVAQ 334
+++ +E +T ++ I++QE K HT+LE R + VELC
Sbjct: 1408 VSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQVELCE---M 1464
Query: 335 YRLMKEVQEITHNVARLKETLAQAQAELKGLHRRQLALQEEIQVKENTI 383
+ +E+ E + +++ L A K + +LQEE+ + TI
Sbjct: 1465 KQKPEEIGEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARGTI 1513
Score = 37.4 bits (85), Expect = 0.025
Identities = 69/360 (19%), Positives = 137/360 (38%), Gaps = 46/360 (12%)
Query: 21 KNQYHRADAQRSRSERLVAESQRLVDEIEKTTRKSQSDVNKKLEQRLEEVQ----FWKKE 76
+ + HR A S S++ +AE + + ++K K ++ KL++ L+ + + E
Sbjct: 2638 EEEVHRLSALFSSSQKRIAELEEELVCVQKEAAKKVGEIEDKLKKELKHLHHDAGIMRNE 2697
Query: 77 LDDKLEQLVNVTDDLLIYKIRLEKALETLKEPLHITETCLAYREKRIGIDLVHDTVEHEL 136
+ E++ + DL+ + +K L KE +T ++ + D EL
Sbjct: 2698 TETAEERVAELARDLVEME---QKLLMVTKENKGLTAQIQSFGRSMSSLQNSRDHANEEL 2754
Query: 137 IKEAEIIQGIMALLTRTLEEASEQIRMNRSAKYNLEKDLKDKFVALTIDDICFSLNNNSP 196
E+ + A L + L + EQ +NR E+D + + FS+N+
Sbjct: 2755 ---DELKRKYDASL-KELAQLKEQGLLNR------ERD-------ALLSETAFSMNSTEE 2797
Query: 197 NIRYSENAVRIEPNSVSLEDWLDFSSTNVEKADKQRNNSLMLKALVDRILSQTANDLRK- 255
N + ++ +S ++ L S+ +E + Q + A + N+L K
Sbjct: 2798 N--SLSHLEKLNQQLLSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERDHLWNELEKF 2855
Query: 256 ---------------QCDVVDTAFKNGLKDTKDARDKLADHLAKVMEEIASQEKNITALE 300
+ K + ++ RD+L L + ++ + IT L
Sbjct: 2856 RKSEEGKQRSAAQPSTSPAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEITELH 2915
Query: 301 --KAILDQEGPAKVAHTRLETRTHRPNVELCRDVAQYRLMKEVQEITHNVARLKETLAQA 358
KA L + A ++ + N+ ++ Q R+ K EI + R+KE A
Sbjct: 2916 PLKAQLQEYQDKTKAFQIMQEELRQENLSWQHELHQLRMEKSSWEI--HERRMKEQYLMA 2973
Score = 34.3 bits (77), Expect = 0.22
Identities = 74/421 (17%), Positives = 174/421 (41%), Gaps = 75/421 (17%)
Query: 23 QYHRADAQRSRSERLVAESQRLVDEIEKTTRKSQSDVNKKLEQRLEE-------VQFWKK 75
Q H+ + +R +S+ L E+E K+Q K L+++ +E ++ +KK
Sbjct: 680 QCHQDELERLKSQIL---------ELELNFHKAQEIYEKNLDEKAKEISNLNQLIEEFKK 730
Query: 76 ELDDKLEQLVNVTD--DLLIYKIRLEKALETLKEPLHITETCLAYREKRIGIDLVHDTVE 133
D+ +++ D L+ +++ + L+ + E LA E++ +D T
Sbjct: 731 NADNNSSAFTALSEERDQLLSQVKELSMVTELRAQVKQLEMNLAEAERQRRLDYESQTAH 790
Query: 134 HELIKE---------------AEIIQGIMALLTRTLEEASEQIRMNRSAKYNLEKDLKD- 177
L+ E E++Q + + E S IR +S N E ++ +
Sbjct: 791 DNLLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEG 850
Query: 178 ----KFVALTIDDICFSLNNNSPNIRYSENAV-----RIEPNSVSLED------WLDFSS 222
+ ++ ++++ +L+ I + + +E ++E+ + FS
Sbjct: 851 AERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSM 910
Query: 223 TN--VEKADKQRNNSLMLKALVDRI-LSQTANDLRKQCDVVDTAFKNGLKDTKD------ 273
T V+ +++ + + +K L +++ L A + +K+ D +GLK D
Sbjct: 911 TEKMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQNYDEMSPAG 970
Query: 274 --ARDKLADHLAKVMEEIASQEKNITAL---EKAILDQEG--PAKVAHTRLETR------ 320
++++L + +E +++ + A K +L + ++A+ + E++
Sbjct: 971 QISKEELQHEFDLLKKENEQRKRKLQAALINRKELLQRVSRLEEELANLKDESKKEIPLS 1030
Query: 321 -THRPNVELCRDVAQYRLMKEVQEITHNVARLKETLAQAQAELKGLHR---RQLALQEEI 376
T R VE ++ +Y + LK+T+++ + EL+ + + +LA +E+
Sbjct: 1031 ETERGEVEEDKENKEYSEKCVTSKCQEIEIYLKQTISEKEVELQHIRKDLEEKLAAEEQF 1090
Query: 377 Q 377
Q
Sbjct: 1091 Q 1091
Score = 31.6 bits (70), Expect = 1.4
Identities = 72/439 (16%), Positives = 164/439 (37%), Gaps = 78/439 (17%)
Query: 25 HRADAQRSRSERLVAESQRLVDEIEKTTRKSQSDVNKKLEQRLEEVQFWKKELDDKLEQL 84
H +A R + L + R + +K T K + +++E+ E+++ + K K+ +L
Sbjct: 1634 HVVEAVRQEKQELYGKL-RSTEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILEL 1692
Query: 85 VNVTDDLLIYKIRLEKALETLKEPLH-ITETCLAYREKRIGIDLVHDTVEHELIKEAEII 143
D L + + A +T KE + + + + +E+ + + ++T L K+ + +
Sbjct: 1693 EEENDRL---RAEVHPAGDTAKECMETLLSSNASMKEELERVKMEYET----LSKKFQSL 1745
Query: 144 QGIMALLTRTLEEASEQIRMNRSAKYNL-------------------------EKDLKDK 178
L+ +++ QI N S + NL E+D
Sbjct: 1746 MSEKDSLSEEVQDLKHQIEGNVSKQANLEATEKHDNQTNVTEEGTQSIPGETEEQDSLSM 1805
Query: 179 FVALTIDDICFSLNNNSPNI-----------RYSENAVRIEPNSVSLEDWLDFSSTNVEK 227
T + S + +P + Y + +++ LE+ + +
Sbjct: 1806 STRPTCSESVPSAKSANPAVSKDFSSHDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQT 1865
Query: 228 ADKQRNNSLM--------LKALVDRILSQTA--NDLRKQCDVVDTAFKNGLKDTKDARDK 277
+ ++N L LK L + + ++++ V + ++ D ++
Sbjct: 1866 LENEKNTLLSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAEEEKDDLEER 1925
Query: 278 LADHLAKVM-----------------EEIASQEKNITALEKAILDQEGPAKVAHTRLETR 320
L + LA++ E + S+ KN+ + +++ T++E+
Sbjct: 1926 LMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESE 1985
Query: 321 THRPNVELCRDVAQYRLMKEVQEITHNVARLKETLAQAQAELKGLHRRQLALQEEIQVKE 380
+ +E + KE +H L+E L + Q E+K L + + QE+I E
Sbjct: 1986 IRKEYLEKIQGA-----QKEPGNKSH-AKELQELLKEKQQEVKQLQKDCIRYQEKISALE 2039
Query: 381 NTIYIDEVLCMQMRKSIPL 399
T+ E + + +K + +
Sbjct: 2040 RTVKALEFVQTESQKDLEI 2058
Score = 29.6 bits (65), Expect = 5.3
Identities = 51/268 (19%), Positives = 107/268 (39%), Gaps = 20/268 (7%)
Query: 35 ERLVAESQRLVDEIEKTTRKSQSDVNKKLEQRLEEVQFWKKELDDKLEQLVNVTDDLLIY 94
E V Q+L ++ E + + EQ ++V +E D + E V + +D L+
Sbjct: 183 EEFVMMKQQLQEKEEFISTLQAQLSQTQAEQAAQQVV---REKDARFETQVRLHEDELLQ 239
Query: 95 KIRLEKALETLKEPLHITETCLA-YREKRIGIDLVHDTVEHELIKEAEIIQGIMALLTRT 153
+ +++ L + + L + E +G V D ++ EL AE I++ +
Sbjct: 240 LVTQADVETEMQQKLRVLQRKLEEHEESLVGRAQVVDLLQQELTA-AEQRNQILSQQLQQ 298
Query: 154 LEEASEQIRMNRSAKYNLEKDLKDKFVALTIDDICFSLNNNSPNIRYS----ENAVRIEP 209
+E +R + K L +K + L + + S +N + + E A + +
Sbjct: 299 MEAEHNTLRNTVETEREESKILLEK-MELEVAERKLSFHNLQEEMHHLLEQFEQAGQAQA 357
Query: 210 NSVSLEDWLDFSSTNVEKADKQRNNSLMLKALVDRILSQTANDLRKQCDVVDTAFKNGLK 269
S L+ KA+ + S +L L +T +L+ CD + L+
Sbjct: 358 ELESRYSALE----QKHKAEMEEKTSHILS------LQKTGQELQSACDALKDQNSKLLQ 407
Query: 270 DTKDARDKLADHLAKVMEEIASQEKNIT 297
D + + A + ++ +++ + K I+
Sbjct: 408 DKNEQAVQSAQTIQQLEDQLQQKSKEIS 435
>gi|56961680 coiled-coil domain containing 147 [Homo sapiens]
Length = 872
Score = 48.9 bits (115), Expect = 8e-06
Identities = 72/388 (18%), Positives = 158/388 (40%), Gaps = 58/388 (14%)
Query: 30 QRSRSERLVAESQRLVDEIEKTTRKSQSDVNK------KLEQRLEEVQFWKKELDDKLEQ 83
Q+ +ER E++ + + ++ ++ Q++ ++ KLE+ L+++Q ++D + +
Sbjct: 182 QQQETERSKEEAEHAISQFQQEIQQRQNEASREFRKKEKLEKELKQIQ---ADMDSRQTE 238
Query: 84 LVNVTDDLLIYKIRLEKALETLKEPLHITETCLAYREK--RIGIDLVHDTVEHELIKEAE 141
+ + + K L+K + LKE + E E+ L + +H L+ E
Sbjct: 239 IKALQQYVQKSKEELQKLEQQLKEQKILNERAAKELEQFQMRNAKLQQENEQHSLVCEQL 298
Query: 142 IIQGIM-ALLTRTLEEASEQIRMNRSAKYNLEKDLKDKFVALTIDDICFSLNNNSPNIRY 200
+ AL + EE Q+R++ + + + K +
Sbjct: 299 SQENQQKALELKAKEEEVHQMRLDIGKLNKIREQIHKKLH-----------HTEDQKAEV 347
Query: 201 SENAVRIEPNSVSLEDWLDFSSTNVEKADKQRNNSLMLKALVDRILSQTANDLRKQCDVV 260
++ ++ V LE ++ S E K + L + ++++ + + N +KQ D+V
Sbjct: 348 EQHKETLKNQIVGLEREVEASKKQAELDRKAMDELLRERDILNKNMLKAVNATQKQTDLV 407
Query: 261 ---DTAFKN------GLKDTKDARDKLADHLAKVMEEIASQEKNITALEKAILDQEG--- 308
+ A +N KD + K+ HL K + +Q ++T +K +++ E
Sbjct: 408 KLHEQAKRNLEGEIQNYKDEAQKQRKIIFHLEKERDRYINQASDLT--QKVLMNMEDIKV 465
Query: 309 --------PAKVAHTRLETRTHRPNVELCR---DVAQYRLMKEVQEIT----------HN 347
K+A + ++ + + E R ++ L++ EIT H
Sbjct: 466 RETQIFDYRKKIAESEIKLKQQQNLYEAVRSDRNLYSKNLVEAQDEITDMKRKLKIMIHQ 525
Query: 348 VARLKETLAQAQAELKGLHRRQLALQEE 375
V LKE ++ ++ L LH Q +++E
Sbjct: 526 VDELKEDISAKESALVKLHLEQQRIEKE 553
Score = 36.2 bits (82), Expect = 0.057
Identities = 35/171 (20%), Positives = 82/171 (47%), Gaps = 17/171 (9%)
Query: 15 EWHIANKNQYHRADAQRSRSERLVAESQRLVDEIEKTTRKSQSDVNKKLEQRLEEVQFWK 74
E I N+ + + R+ +L E+++ E+ ++++Q K LE + +E + +
Sbjct: 262 EQKILNERAAKELEQFQMRNAKLQQENEQHSLVCEQLSQENQQ---KALELKAKEEEVHQ 318
Query: 75 KELD--------DKLEQLVNVTDDLLIYKIRLEKALETLKEPLHITETCLAYREKRIGID 126
LD +++ + ++ T+D K +E+ ETLK + E + +K+ +D
Sbjct: 319 MRLDIGKLNKIREQIHKKLHHTED---QKAEVEQHKETLKNQIVGLEREVEASKKQAELD 375
Query: 127 LVHDTVEHELIKEAEIIQGIMALLTRTLEEASEQIRMNRSAKYNLEKDLKD 177
EL++E +I+ M ++ ++ ++++ AK NLE ++++
Sbjct: 376 R---KAMDELLRERDILNKNMLKAVNATQKQTDLVKLHEQAKRNLEGEIQN 423
Score = 30.0 bits (66), Expect = 4.1
Identities = 34/165 (20%), Positives = 65/165 (39%), Gaps = 21/165 (12%)
Query: 226 EKADKQRNNSLMLKALVDRILSQTANDLRKQCDVVDTAFKNGLKDTKDARDKLADHLAKV 285
EK + L + +V+ TA L + + K ++ D D K
Sbjct: 57 EKRLMAKCRELNAEIVVNSAKVATALKLSQDDQTTIASLKKEIEKAWKMVDSAYDKEQKA 116
Query: 286 MEEIASQEKNITALEKAILDQEGPAKVAHTRLETRTHRPNVELCRDVAQYR--LMKEVQE 343
E I + ++ I L K + G + H+ + RD+ +++ + KE +
Sbjct: 117 KETILALKEEIVNLTKLVEQGSGLSMDQHSNI------------RDLLRFKEEVTKERDQ 164
Query: 344 ITHNVARLKETLAQAQAELKGLHRRQ-------LALQEEIQVKEN 381
+ V +L+E+LAQ + + R + Q+EIQ ++N
Sbjct: 165 LLSEVVKLRESLAQTTEQQQETERSKEEAEHAISQFQQEIQQRQN 209
Score = 30.0 bits (66), Expect = 4.1
Identities = 34/143 (23%), Positives = 64/143 (44%), Gaps = 10/143 (6%)
Query: 18 IANKNQYHRADAQRSRSERLVAESQRLVDEIEKTTRKSQSDVNKKLEQRLEEVQFWKKEL 77
I + + +A+ Q+ R + L E++ +++ E RK + + +RL + KKEL
Sbjct: 550 IEKEKETLKAELQKLRQQAL--ETKHFIEKQEAEERKLLRIIAEADGERLRQ----KKEL 603
Query: 78 DDKLEQLVNVTDDLLIYKIRLEKALETLKEPLHITETCLAYREKRIGIDLVHDTVEHELI 137
D Q+++ D L +R L L E + I ++ L E + L + I
Sbjct: 604 D----QVISERDILGSQLVRRNDELALLYEKIKIQQSVLNKGESQYNQRLEDMRILRLEI 659
Query: 138 KEAEIIQGIMALLTRTLEEASEQ 160
K+ +GI+A +EE ++
Sbjct: 660 KKLRREKGILARSMANVEELRQE 682
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.131 0.362
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,186,188
Number of Sequences: 37866
Number of extensions: 571616
Number of successful extensions: 4603
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 44
Number of HSP's successfully gapped in prelim test: 397
Number of HSP's that attempted gapping in prelim test: 3442
Number of HSP's gapped (non-prelim): 1334
length of query: 418
length of database: 18,247,518
effective HSP length: 105
effective length of query: 313
effective length of database: 14,271,588
effective search space: 4467007044
effective search space used: 4467007044
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.