Guide to the Human Genome
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Search of human proteins with 11067747

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|11067747 CDC5-like [Homo sapiens]
         (802 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|11067747 CDC5-like [Homo sapiens]                                 1593   0.0  
gi|239735490 v-myb myeloblastosis viral oncogene homolog isoform...    73   9e-13
gi|239735496 v-myb myeloblastosis viral oncogene homolog isoform...    73   1e-12
gi|239735494 v-myb myeloblastosis viral oncogene homolog isoform...    73   1e-12
gi|239735492 v-myb myeloblastosis viral oncogene homolog isoform...    73   1e-12
gi|239735488 v-myb myeloblastosis viral oncogene homolog isoform...    73   1e-12
gi|46361980 v-myb myeloblastosis viral oncogene homolog isoform ...    73   1e-12
gi|194328729 v-myb myeloblastosis viral oncogene homolog isoform...    73   1e-12
gi|194328727 v-myb myeloblastosis viral oncogene homolog isoform...    73   1e-12
gi|221139773 v-myb myeloblastosis viral oncogene homolog (avian)...    72   2e-12
gi|122937231 v-myb myeloblastosis viral oncogene homolog (avian)...    72   2e-12
gi|4505293 MYB-related protein B [Homo sapiens]                        72   3e-12
gi|92859678 small nuclear RNA activating complex, polypeptide 4,...    62   2e-09
gi|55741709 RNA binding motif protein 25 [Homo sapiens]                49   1e-05
gi|34878777 ring finger protein 20 [Homo sapiens]                      49   2e-05
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]             47   9e-05
gi|58530840 desmoplakin isoform I [Homo sapiens]                       45   2e-04
gi|71061468 centromere protein E [Homo sapiens]                        45   2e-04
gi|31982906 cingulin-like 1 [Homo sapiens]                             45   2e-04
gi|41322923 plectin 1 isoform 11 [Homo sapiens]                        45   3e-04
gi|41322914 plectin 1 isoform 10 [Homo sapiens]                        45   3e-04
gi|41322919 plectin 1 isoform 8 [Homo sapiens]                         45   3e-04
gi|41322910 plectin 1 isoform 7 [Homo sapiens]                         45   3e-04
gi|41322916 plectin 1 isoform 6 [Homo sapiens]                         45   3e-04
gi|41322908 plectin 1 isoform 3 [Homo sapiens]                         45   3e-04
gi|41322912 plectin 1 isoform 2 [Homo sapiens]                         45   3e-04
gi|47607492 plectin 1 isoform 1 [Homo sapiens]                         45   3e-04
gi|22538461 nuclear receptor co-repressor 1 [Homo sapiens]             45   3e-04
gi|169167715 PREDICTED: hypothetical protein [Homo sapiens]            45   3e-04
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]            45   3e-04

>gi|11067747 CDC5-like [Homo sapiens]
          Length = 802

 Score = 1593 bits (4125), Expect = 0.0
 Identities = 802/802 (100%), Positives = 802/802 (100%)

Query: 1   MPRIMIKGGVWRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKK 60
           MPRIMIKGGVWRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKK
Sbjct: 1   MPRIMIKGGVWRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKK 60

Query: 61  TEWSREEEEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLLDKAAQRDNEEETTDDP 120
           TEWSREEEEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLLDKAAQRDNEEETTDDP
Sbjct: 61  TEWSREEEEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLLDKAAQRDNEEETTDDP 120

Query: 121 RKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEAR 180
           RKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEAR
Sbjct: 121 RKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEAR 180

Query: 181 RLAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFR 240
           RLAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFR
Sbjct: 181 RLAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFR 240

Query: 241 KLRQQDLDGELRSEKEGRDRKKDKQHLKRKKESDLPSAILQTSGVSEFTKKRSKLVLPAP 300
           KLRQQDLDGELRSEKEGRDRKKDKQHLKRKKESDLPSAILQTSGVSEFTKKRSKLVLPAP
Sbjct: 241 KLRQQDLDGELRSEKEGRDRKKDKQHLKRKKESDLPSAILQTSGVSEFTKKRSKLVLPAP 300

Query: 301 QISDAELQEVVKVGQASEIARQTAEESGITNSASSTLLSEYNVTNNSVALRTPRTPASQD 360
           QISDAELQEVVKVGQASEIARQTAEESGITNSASSTLLSEYNVTNNSVALRTPRTPASQD
Sbjct: 301 QISDAELQEVVKVGQASEIARQTAEESGITNSASSTLLSEYNVTNNSVALRTPRTPASQD 360

Query: 361 RILQEAQNLMALTNVDTPLKGGLNTPLHESDFSGVTPQRQVVQTPNTVLSTPFRTPSNGA 420
           RILQEAQNLMALTNVDTPLKGGLNTPLHESDFSGVTPQRQVVQTPNTVLSTPFRTPSNGA
Sbjct: 361 RILQEAQNLMALTNVDTPLKGGLNTPLHESDFSGVTPQRQVVQTPNTVLSTPFRTPSNGA 420

Query: 421 EGLTPRSGTTPKPVINSTPGRTPLRDKLNINPEDGMADYSDPSYVKQMERESREHLRLGL 480
           EGLTPRSGTTPKPVINSTPGRTPLRDKLNINPEDGMADYSDPSYVKQMERESREHLRLGL
Sbjct: 421 EGLTPRSGTTPKPVINSTPGRTPLRDKLNINPEDGMADYSDPSYVKQMERESREHLRLGL 480

Query: 481 LGLPAPKNDFEIVLPENAEKELEEREIDDTYIEDAADVDARKQAIRDAERVKEMKRMHKA 540
           LGLPAPKNDFEIVLPENAEKELEEREIDDTYIEDAADVDARKQAIRDAERVKEMKRMHKA
Sbjct: 481 LGLPAPKNDFEIVLPENAEKELEEREIDDTYIEDAADVDARKQAIRDAERVKEMKRMHKA 540

Query: 541 VQKDLPRPSEVNETILRPLNVEPPLTDLQKSEELIKKEMITMLHYDLLHHPYEPSGNKKG 600
           VQKDLPRPSEVNETILRPLNVEPPLTDLQKSEELIKKEMITMLHYDLLHHPYEPSGNKKG
Sbjct: 541 VQKDLPRPSEVNETILRPLNVEPPLTDLQKSEELIKKEMITMLHYDLLHHPYEPSGNKKG 600

Query: 601 KTVGFGTNNSEHITYLEHNPYEKFSKEELKKAQDVLVQEMEVVKQGMSHGELSSEAYNQV 660
           KTVGFGTNNSEHITYLEHNPYEKFSKEELKKAQDVLVQEMEVVKQGMSHGELSSEAYNQV
Sbjct: 601 KTVGFGTNNSEHITYLEHNPYEKFSKEELKKAQDVLVQEMEVVKQGMSHGELSSEAYNQV 660

Query: 661 WEECYSQVLYLPGQSRYTRANLASKKDRIESLEKRLEINRGHMTTEAKRAAKMEKKMKIL 720
           WEECYSQVLYLPGQSRYTRANLASKKDRIESLEKRLEINRGHMTTEAKRAAKMEKKMKIL
Sbjct: 661 WEECYSQVLYLPGQSRYTRANLASKKDRIESLEKRLEINRGHMTTEAKRAAKMEKKMKIL 720

Query: 721 LGGYQSRAMGLMKQLNDLWDQIEQAHLELRTFEELKKHEDSAIPRRLECLKEDVQRQQER 780
           LGGYQSRAMGLMKQLNDLWDQIEQAHLELRTFEELKKHEDSAIPRRLECLKEDVQRQQER
Sbjct: 721 LGGYQSRAMGLMKQLNDLWDQIEQAHLELRTFEELKKHEDSAIPRRLECLKEDVQRQQER 780

Query: 781 EKELQHRYADLLLEKETLKSKF 802
           EKELQHRYADLLLEKETLKSKF
Sbjct: 781 EKELQHRYADLLLEKETLKSKF 802


>gi|239735490 v-myb myeloblastosis viral oncogene homolog isoform 5
           [Homo sapiens]
          Length = 555

 Score = 73.2 bits (178), Expect = 9e-13
 Identities = 77/339 (22%), Positives = 130/339 (38%), Gaps = 23/339 (6%)

Query: 9   GVWRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEE 68
           G W   ED+ +   V KYG  +WS IA  L  +  KQC+ RW+  L+P +KKT W+ EE+
Sbjct: 93  GPWTKEEDQRVIELVQKYGPKRWSVIAKHLKGRIGKQCRERWHNHLNPEVKKTSWTEEED 152

Query: 69  EKLLHLAKLMPTQWRTIAPII-GRTAAQCLEHYEFLLDKAAQRD---NEEETTDDPRKLK 124
             +    K +  +W  IA ++ GRT      H+   + +  +++    E      P    
Sbjct: 153 RIIYQAHKRLGNRWAEIAKLLPGRTDNAIKNHWNSTMRRKVEQEGYLQESSKASQPAVAT 212

Query: 125 PGEID---------PNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQ 175
             + +         P     PA   P   ++     +SEA+    N         A    
Sbjct: 213 SFQKNSHLMGFAQAPPTAQLPATGQPTVNNDYSYYHISEAQ----NVSSHVPYPVALHVN 268

Query: 176 LEEARRLAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFYDTSEENYQAL 235
           +    + AA   +R       E +K+ K    +  + E   + +  L F +TS  N++  
Sbjct: 269 IVNVPQPAAAAIQRHYNDEDPEKEKRIKELELLLMSTENELKGQQVLPFLNTS-SNHENS 327

Query: 236 DADFRKLRQQDLDGELRSEKEGRDRKKDKQHLKRKKESDLPSAILQTSGVSEFTKKRSKL 295
           D +   L    L G   +      R +  +  K       P+        S  T    K 
Sbjct: 328 DLEMPSLTSTPLIGHKLTVTTPFHRDQTVKTQKENTVFRTPAIKRSILESSPRTPTPFKH 387

Query: 296 VLPAPQISDAELQEVVK-----VGQASEIARQTAEESGI 329
            L A +I    L+ + +     V    ++ +Q ++ESGI
Sbjct: 388 ALAAQEIKYGPLKMLPQTPSHLVEDLQDVIKQESDESGI 426



 Score = 67.0 bits (162), Expect = 7e-11
 Identities = 36/110 (32%), Positives = 59/110 (53%), Gaps = 2/110 (1%)

Query: 11  WRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEK 70
           W   EDE LK  V + G + W  IA+ L  ++  QC+ RW + L+P + K  W++EE+++
Sbjct: 43  WTREEDEKLKKLVEQNGTDDWKVIANYLPNRTDVQCQHRWQKVLNPELIKGPWTKEEDQR 102

Query: 71  LLHLA-KLMPTQWRTIAP-IIGRTAAQCLEHYEFLLDKAAQRDNEEETTD 118
           ++ L  K  P +W  IA  + GR   QC E +   L+   ++ +  E  D
Sbjct: 103 VIELVQKYGPKRWSVIAKHLKGRIGKQCRERWHNHLNPEVKKTSWTEEED 152



 Score = 34.3 bits (77), Expect = 0.47
 Identities = 19/48 (39%), Positives = 28/48 (58%), Gaps = 2/48 (4%)

Query: 60  KTEWSREEEEKLLHLAKLMPT-QWRTIAPII-GRTAAQCLEHYEFLLD 105
           KT W+REE+EKL  L +   T  W+ IA  +  RT  QC   ++ +L+
Sbjct: 40  KTRWTREEDEKLKKLVEQNGTDDWKVIANYLPNRTDVQCQHRWQKVLN 87


>gi|239735496 v-myb myeloblastosis viral oncogene homolog isoform 8
           [Homo sapiens]
          Length = 605

 Score = 72.8 bits (177), Expect = 1e-12
 Identities = 34/104 (32%), Positives = 55/104 (52%), Gaps = 1/104 (0%)

Query: 9   GVWRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEE 68
           G W   ED+ +   V KYG  +WS IA  L  +  KQC+ RW+  L+P +KKT W+ EE+
Sbjct: 93  GPWTKEEDQRVIELVQKYGPKRWSVIAKHLKGRIGKQCRERWHNHLNPEVKKTSWTEEED 152

Query: 69  EKLLHLAKLMPTQWRTIAPII-GRTAAQCLEHYEFLLDKAAQRD 111
             +    K +  +W  IA ++ GRT      H+   + +  +++
Sbjct: 153 RIIYQAHKRLGNRWAEIAKLLPGRTDNAIKNHWNSTMRRKVEQE 196



 Score = 67.0 bits (162), Expect = 7e-11
 Identities = 36/110 (32%), Positives = 59/110 (53%), Gaps = 2/110 (1%)

Query: 11  WRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEK 70
           W   EDE LK  V + G + W  IA+ L  ++  QC+ RW + L+P + K  W++EE+++
Sbjct: 43  WTREEDEKLKKLVEQNGTDDWKVIANYLPNRTDVQCQHRWQKVLNPELIKGPWTKEEDQR 102

Query: 71  LLHLA-KLMPTQWRTIAP-IIGRTAAQCLEHYEFLLDKAAQRDNEEETTD 118
           ++ L  K  P +W  IA  + GR   QC E +   L+   ++ +  E  D
Sbjct: 103 VIELVQKYGPKRWSVIAKHLKGRIGKQCRERWHNHLNPEVKKTSWTEEED 152



 Score = 34.3 bits (77), Expect = 0.47
 Identities = 19/48 (39%), Positives = 28/48 (58%), Gaps = 2/48 (4%)

Query: 60  KTEWSREEEEKLLHLAKLMPT-QWRTIAPII-GRTAAQCLEHYEFLLD 105
           KT W+REE+EKL  L +   T  W+ IA  +  RT  QC   ++ +L+
Sbjct: 40  KTRWTREEDEKLKKLVEQNGTDDWKVIANYLPNRTDVQCQHRWQKVLN 87


>gi|239735494 v-myb myeloblastosis viral oncogene homolog isoform 7
           [Homo sapiens]
          Length = 603

 Score = 72.8 bits (177), Expect = 1e-12
 Identities = 34/104 (32%), Positives = 55/104 (52%), Gaps = 1/104 (0%)

Query: 9   GVWRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEE 68
           G W   ED+ +   V KYG  +WS IA  L  +  KQC+ RW+  L+P +KKT W+ EE+
Sbjct: 93  GPWTKEEDQRVIELVQKYGPKRWSVIAKHLKGRIGKQCRERWHNHLNPEVKKTSWTEEED 152

Query: 69  EKLLHLAKLMPTQWRTIAPII-GRTAAQCLEHYEFLLDKAAQRD 111
             +    K +  +W  IA ++ GRT      H+   + +  +++
Sbjct: 153 RIIYQAHKRLGNRWAEIAKLLPGRTDNAIKNHWNSTMRRKVEQE 196



 Score = 67.0 bits (162), Expect = 7e-11
 Identities = 36/110 (32%), Positives = 59/110 (53%), Gaps = 2/110 (1%)

Query: 11  WRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEK 70
           W   EDE LK  V + G + W  IA+ L  ++  QC+ RW + L+P + K  W++EE+++
Sbjct: 43  WTREEDEKLKKLVEQNGTDDWKVIANYLPNRTDVQCQHRWQKVLNPELIKGPWTKEEDQR 102

Query: 71  LLHLA-KLMPTQWRTIAP-IIGRTAAQCLEHYEFLLDKAAQRDNEEETTD 118
           ++ L  K  P +W  IA  + GR   QC E +   L+   ++ +  E  D
Sbjct: 103 VIELVQKYGPKRWSVIAKHLKGRIGKQCRERWHNHLNPEVKKTSWTEEED 152



 Score = 34.3 bits (77), Expect = 0.47
 Identities = 19/48 (39%), Positives = 28/48 (58%), Gaps = 2/48 (4%)

Query: 60  KTEWSREEEEKLLHLAKLMPT-QWRTIAPII-GRTAAQCLEHYEFLLD 105
           KT W+REE+EKL  L +   T  W+ IA  +  RT  QC   ++ +L+
Sbjct: 40  KTRWTREEDEKLKKLVEQNGTDDWKVIANYLPNRTDVQCQHRWQKVLN 87


>gi|239735492 v-myb myeloblastosis viral oncogene homolog isoform 6
           [Homo sapiens]
          Length = 745

 Score = 72.8 bits (177), Expect = 1e-12
 Identities = 34/104 (32%), Positives = 55/104 (52%), Gaps = 1/104 (0%)

Query: 9   GVWRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEE 68
           G W   ED+ +   V KYG  +WS IA  L  +  KQC+ RW+  L+P +KKT W+ EE+
Sbjct: 93  GPWTKEEDQRVIELVQKYGPKRWSVIAKHLKGRIGKQCRERWHNHLNPEVKKTSWTEEED 152

Query: 69  EKLLHLAKLMPTQWRTIAPII-GRTAAQCLEHYEFLLDKAAQRD 111
             +    K +  +W  IA ++ GRT      H+   + +  +++
Sbjct: 153 RIIYQAHKRLGNRWAEIAKLLPGRTDNAIKNHWNSTMRRKVEQE 196



 Score = 67.0 bits (162), Expect = 7e-11
 Identities = 36/110 (32%), Positives = 59/110 (53%), Gaps = 2/110 (1%)

Query: 11  WRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEK 70
           W   EDE LK  V + G + W  IA+ L  ++  QC+ RW + L+P + K  W++EE+++
Sbjct: 43  WTREEDEKLKKLVEQNGTDDWKVIANYLPNRTDVQCQHRWQKVLNPELIKGPWTKEEDQR 102

Query: 71  LLHLA-KLMPTQWRTIAP-IIGRTAAQCLEHYEFLLDKAAQRDNEEETTD 118
           ++ L  K  P +W  IA  + GR   QC E +   L+   ++ +  E  D
Sbjct: 103 VIELVQKYGPKRWSVIAKHLKGRIGKQCRERWHNHLNPEVKKTSWTEEED 152



 Score = 34.3 bits (77), Expect = 0.47
 Identities = 19/48 (39%), Positives = 28/48 (58%), Gaps = 2/48 (4%)

Query: 60  KTEWSREEEEKLLHLAKLMPT-QWRTIAPII-GRTAAQCLEHYEFLLD 105
           KT W+REE+EKL  L +   T  W+ IA  +  RT  QC   ++ +L+
Sbjct: 40  KTRWTREEDEKLKKLVEQNGTDDWKVIANYLPNRTDVQCQHRWQKVLN 87


>gi|239735488 v-myb myeloblastosis viral oncogene homolog isoform 4
           [Homo sapiens]
          Length = 758

 Score = 72.8 bits (177), Expect = 1e-12
 Identities = 34/104 (32%), Positives = 55/104 (52%), Gaps = 1/104 (0%)

Query: 9   GVWRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEE 68
           G W   ED+ +   V KYG  +WS IA  L  +  KQC+ RW+  L+P +KKT W+ EE+
Sbjct: 93  GPWTKEEDQRVIELVQKYGPKRWSVIAKHLKGRIGKQCRERWHNHLNPEVKKTSWTEEED 152

Query: 69  EKLLHLAKLMPTQWRTIAPII-GRTAAQCLEHYEFLLDKAAQRD 111
             +    K +  +W  IA ++ GRT      H+   + +  +++
Sbjct: 153 RIIYQAHKRLGNRWAEIAKLLPGRTDNAIKNHWNSTMRRKVEQE 196



 Score = 67.0 bits (162), Expect = 7e-11
 Identities = 36/110 (32%), Positives = 59/110 (53%), Gaps = 2/110 (1%)

Query: 11  WRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEK 70
           W   EDE LK  V + G + W  IA+ L  ++  QC+ RW + L+P + K  W++EE+++
Sbjct: 43  WTREEDEKLKKLVEQNGTDDWKVIANYLPNRTDVQCQHRWQKVLNPELIKGPWTKEEDQR 102

Query: 71  LLHLA-KLMPTQWRTIAP-IIGRTAAQCLEHYEFLLDKAAQRDNEEETTD 118
           ++ L  K  P +W  IA  + GR   QC E +   L+   ++ +  E  D
Sbjct: 103 VIELVQKYGPKRWSVIAKHLKGRIGKQCRERWHNHLNPEVKKTSWTEEED 152



 Score = 34.3 bits (77), Expect = 0.47
 Identities = 19/48 (39%), Positives = 28/48 (58%), Gaps = 2/48 (4%)

Query: 60  KTEWSREEEEKLLHLAKLMPT-QWRTIAPII-GRTAAQCLEHYEFLLD 105
           KT W+REE+EKL  L +   T  W+ IA  +  RT  QC   ++ +L+
Sbjct: 40  KTRWTREEDEKLKKLVEQNGTDDWKVIANYLPNRTDVQCQHRWQKVLN 87


>gi|46361980 v-myb myeloblastosis viral oncogene homolog isoform 2
           [Homo sapiens]
          Length = 640

 Score = 72.8 bits (177), Expect = 1e-12
 Identities = 34/104 (32%), Positives = 55/104 (52%), Gaps = 1/104 (0%)

Query: 9   GVWRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEE 68
           G W   ED+ +   V KYG  +WS IA  L  +  KQC+ RW+  L+P +KKT W+ EE+
Sbjct: 93  GPWTKEEDQRVIELVQKYGPKRWSVIAKHLKGRIGKQCRERWHNHLNPEVKKTSWTEEED 152

Query: 69  EKLLHLAKLMPTQWRTIAPII-GRTAAQCLEHYEFLLDKAAQRD 111
             +    K +  +W  IA ++ GRT      H+   + +  +++
Sbjct: 153 RIIYQAHKRLGNRWAEIAKLLPGRTDNAIKNHWNSTMRRKVEQE 196



 Score = 67.0 bits (162), Expect = 7e-11
 Identities = 36/110 (32%), Positives = 59/110 (53%), Gaps = 2/110 (1%)

Query: 11  WRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEK 70
           W   EDE LK  V + G + W  IA+ L  ++  QC+ RW + L+P + K  W++EE+++
Sbjct: 43  WTREEDEKLKKLVEQNGTDDWKVIANYLPNRTDVQCQHRWQKVLNPELIKGPWTKEEDQR 102

Query: 71  LLHLA-KLMPTQWRTIAP-IIGRTAAQCLEHYEFLLDKAAQRDNEEETTD 118
           ++ L  K  P +W  IA  + GR   QC E +   L+   ++ +  E  D
Sbjct: 103 VIELVQKYGPKRWSVIAKHLKGRIGKQCRERWHNHLNPEVKKTSWTEEED 152



 Score = 34.3 bits (77), Expect = 0.47
 Identities = 19/48 (39%), Positives = 28/48 (58%), Gaps = 2/48 (4%)

Query: 60  KTEWSREEEEKLLHLAKLMPT-QWRTIAPII-GRTAAQCLEHYEFLLD 105
           KT W+REE+EKL  L +   T  W+ IA  +  RT  QC   ++ +L+
Sbjct: 40  KTRWTREEDEKLKKLVEQNGTDDWKVIANYLPNRTDVQCQHRWQKVLN 87


>gi|194328729 v-myb myeloblastosis viral oncogene homolog isoform 1
           [Homo sapiens]
          Length = 761

 Score = 72.8 bits (177), Expect = 1e-12
 Identities = 34/104 (32%), Positives = 55/104 (52%), Gaps = 1/104 (0%)

Query: 9   GVWRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEE 68
           G W   ED+ +   V KYG  +WS IA  L  +  KQC+ RW+  L+P +KKT W+ EE+
Sbjct: 93  GPWTKEEDQRVIELVQKYGPKRWSVIAKHLKGRIGKQCRERWHNHLNPEVKKTSWTEEED 152

Query: 69  EKLLHLAKLMPTQWRTIAPII-GRTAAQCLEHYEFLLDKAAQRD 111
             +    K +  +W  IA ++ GRT      H+   + +  +++
Sbjct: 153 RIIYQAHKRLGNRWAEIAKLLPGRTDNAIKNHWNSTMRRKVEQE 196



 Score = 67.0 bits (162), Expect = 7e-11
 Identities = 36/110 (32%), Positives = 59/110 (53%), Gaps = 2/110 (1%)

Query: 11  WRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEK 70
           W   EDE LK  V + G + W  IA+ L  ++  QC+ RW + L+P + K  W++EE+++
Sbjct: 43  WTREEDEKLKKLVEQNGTDDWKVIANYLPNRTDVQCQHRWQKVLNPELIKGPWTKEEDQR 102

Query: 71  LLHLA-KLMPTQWRTIAP-IIGRTAAQCLEHYEFLLDKAAQRDNEEETTD 118
           ++ L  K  P +W  IA  + GR   QC E +   L+   ++ +  E  D
Sbjct: 103 VIELVQKYGPKRWSVIAKHLKGRIGKQCRERWHNHLNPEVKKTSWTEEED 152



 Score = 34.3 bits (77), Expect = 0.47
 Identities = 19/48 (39%), Positives = 28/48 (58%), Gaps = 2/48 (4%)

Query: 60  KTEWSREEEEKLLHLAKLMPT-QWRTIAPII-GRTAAQCLEHYEFLLD 105
           KT W+REE+EKL  L +   T  W+ IA  +  RT  QC   ++ +L+
Sbjct: 40  KTRWTREEDEKLKKLVEQNGTDDWKVIANYLPNRTDVQCQHRWQKVLN 87


>gi|194328727 v-myb myeloblastosis viral oncogene homolog isoform 3
           [Homo sapiens]
          Length = 637

 Score = 72.8 bits (177), Expect = 1e-12
 Identities = 34/104 (32%), Positives = 55/104 (52%), Gaps = 1/104 (0%)

Query: 9   GVWRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEE 68
           G W   ED+ +   V KYG  +WS IA  L  +  KQC+ RW+  L+P +KKT W+ EE+
Sbjct: 93  GPWTKEEDQRVIELVQKYGPKRWSVIAKHLKGRIGKQCRERWHNHLNPEVKKTSWTEEED 152

Query: 69  EKLLHLAKLMPTQWRTIAPII-GRTAAQCLEHYEFLLDKAAQRD 111
             +    K +  +W  IA ++ GRT      H+   + +  +++
Sbjct: 153 RIIYQAHKRLGNRWAEIAKLLPGRTDNAIKNHWNSTMRRKVEQE 196



 Score = 67.0 bits (162), Expect = 7e-11
 Identities = 36/110 (32%), Positives = 59/110 (53%), Gaps = 2/110 (1%)

Query: 11  WRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEK 70
           W   EDE LK  V + G + W  IA+ L  ++  QC+ RW + L+P + K  W++EE+++
Sbjct: 43  WTREEDEKLKKLVEQNGTDDWKVIANYLPNRTDVQCQHRWQKVLNPELIKGPWTKEEDQR 102

Query: 71  LLHLA-KLMPTQWRTIAP-IIGRTAAQCLEHYEFLLDKAAQRDNEEETTD 118
           ++ L  K  P +W  IA  + GR   QC E +   L+   ++ +  E  D
Sbjct: 103 VIELVQKYGPKRWSVIAKHLKGRIGKQCRERWHNHLNPEVKKTSWTEEED 152



 Score = 34.3 bits (77), Expect = 0.47
 Identities = 19/48 (39%), Positives = 28/48 (58%), Gaps = 2/48 (4%)

Query: 60  KTEWSREEEEKLLHLAKLMPT-QWRTIAPII-GRTAAQCLEHYEFLLD 105
           KT W+REE+EKL  L +   T  W+ IA  +  RT  QC   ++ +L+
Sbjct: 40  KTRWTREEDEKLKKLVEQNGTDDWKVIANYLPNRTDVQCQHRWQKVLN 87


>gi|221139773 v-myb myeloblastosis viral oncogene homolog
           (avian)-like 1 isoform 2 [Homo sapiens]
          Length = 692

 Score = 72.0 bits (175), Expect = 2e-12
 Identities = 33/104 (31%), Positives = 55/104 (52%), Gaps = 1/104 (0%)

Query: 9   GVWRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEE 68
           G W   ED+ +   V KYG  +WS IA  L  +  KQC+ RW+  L+P +KK+ W+ EE+
Sbjct: 88  GPWTKEEDQRVIELVQKYGPKRWSLIAKHLKGRIGKQCRERWHNHLNPEVKKSSWTEEED 147

Query: 69  EKLLHLAKLMPTQWRTIAPII-GRTAAQCLEHYEFLLDKAAQRD 111
             +    K +  +W  IA ++ GRT      H+   + +  +++
Sbjct: 148 RIIYEAHKRLGNRWAEIAKLLPGRTDNSIKNHWNSTMRRKVEQE 191



 Score = 70.1 bits (170), Expect = 8e-12
 Identities = 37/110 (33%), Positives = 61/110 (55%), Gaps = 2/110 (1%)

Query: 11  WRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEK 70
           W   ED+ LK  V ++G + W+ IAS L  +S  QC+ RW + L+P + K  W++EE+++
Sbjct: 38  WTRDEDDKLKKLVEQHGTDDWTLIASHLQNRSDFQCQHRWQKVLNPELIKGPWTKEEDQR 97

Query: 71  LLHLA-KLMPTQWRTIAP-IIGRTAAQCLEHYEFLLDKAAQRDNEEETTD 118
           ++ L  K  P +W  IA  + GR   QC E +   L+   ++ +  E  D
Sbjct: 98  VIELVQKYGPKRWSLIAKHLKGRIGKQCRERWHNHLNPEVKKSSWTEEED 147


>gi|122937231 v-myb myeloblastosis viral oncogene homolog
           (avian)-like 1 isoform 1 [Homo sapiens]
          Length = 752

 Score = 72.0 bits (175), Expect = 2e-12
 Identities = 33/104 (31%), Positives = 55/104 (52%), Gaps = 1/104 (0%)

Query: 9   GVWRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEE 68
           G W   ED+ +   V KYG  +WS IA  L  +  KQC+ RW+  L+P +KK+ W+ EE+
Sbjct: 88  GPWTKEEDQRVIELVQKYGPKRWSLIAKHLKGRIGKQCRERWHNHLNPEVKKSSWTEEED 147

Query: 69  EKLLHLAKLMPTQWRTIAPII-GRTAAQCLEHYEFLLDKAAQRD 111
             +    K +  +W  IA ++ GRT      H+   + +  +++
Sbjct: 148 RIIYEAHKRLGNRWAEIAKLLPGRTDNSIKNHWNSTMRRKVEQE 191



 Score = 70.1 bits (170), Expect = 8e-12
 Identities = 37/110 (33%), Positives = 61/110 (55%), Gaps = 2/110 (1%)

Query: 11  WRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEK 70
           W   ED+ LK  V ++G + W+ IAS L  +S  QC+ RW + L+P + K  W++EE+++
Sbjct: 38  WTRDEDDKLKKLVEQHGTDDWTLIASHLQNRSDFQCQHRWQKVLNPELIKGPWTKEEDQR 97

Query: 71  LLHLA-KLMPTQWRTIAP-IIGRTAAQCLEHYEFLLDKAAQRDNEEETTD 118
           ++ L  K  P +W  IA  + GR   QC E +   L+   ++ +  E  D
Sbjct: 98  VIELVQKYGPKRWSLIAKHLKGRIGKQCRERWHNHLNPEVKKSSWTEEED 147


>gi|4505293 MYB-related protein B [Homo sapiens]
          Length = 700

 Score = 71.6 bits (174), Expect = 3e-12
 Identities = 107/468 (22%), Positives = 187/468 (39%), Gaps = 90/468 (19%)

Query: 9   GVWRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEE 68
           G W   ED+ +   V KYG  QW+ IA  L  +  KQC+ RW+  L+P +KK+ W+ EE+
Sbjct: 84  GPWTKEEDQKVIELVKKYGTKQWTLIAKHLKGRLGKQCRERWHNHLNPEVKKSCWTEEED 143

Query: 69  EKLLHLAKLMPTQWRTIAPII-GRTAAQCLEHYEFLLDKAAQRDNEEETTDDPRKLKPGE 127
             +    K++  +W  IA ++ GRT      H+   + +                   G 
Sbjct: 144 RIICEAHKVLGNRWAEIAKMLPGRTDNAVKNHWNSTIKRKVDTG--------------GF 189

Query: 128 IDPNPETKPARPDPIDM-DEDELEMLSEARAR---LANTQGKKAKRKAREKQLEEARRLA 183
           +  + + KP     +++ D+D L+       +   L N        K  E   EE   LA
Sbjct: 190 LSESKDCKPPVYLLLELEDKDGLQSAQPTEGQGSLLTNWPSVPPTIKEEENSEEE---LA 246

Query: 184 ALQKRRELRAAGIEIQ-----------KKRKRKRGVDYNAEIPFE--------KKPALGF 224
           A    +E    G ++             KR+ + G      +P++          PA+G 
Sbjct: 247 AATTSKEQEPIGTDLDAVRTPEPLEEFPKREDQEGSPPETSLPYKWVVEAANLLIPAVG- 305

Query: 225 YDTSEENYQALDAD---FRKLRQQDLDGELRSEKEGRDRKKDKQ--HLKRKKESDLPSAI 279
             +  E    +++D   +  L + DL  E  +E    +     Q  H ++      PSA+
Sbjct: 306 -SSLSEALDLIESDPDAWCDLSKFDLPEEPSAEDSINNSLVQLQASHQQQVLPPRQPSAL 364

Query: 280 LQTSGVSEFTKKRSKLVLPAPQISDAELQEVVKVGQASEIA----------------RQT 323
           + +  V+E+      +      +S +   E++ +  ++E+                 R+ 
Sbjct: 365 VPS--VTEYRLDGHTI----SDLSRSSRGELIPISPSTEVGGSGIGTPPSVLKRQRKRRV 418

Query: 324 AEESGITNSASSTLLSEYN-VTNNSVALRT-PRTPA-------SQDRILQEAQNLMAL-- 372
           A      NS S + L   N +T  S  ++T P +P+        QD +  E+ +L +   
Sbjct: 419 ALSPVTENSTSLSFLDSCNSLTPKSTPVKTLPFSPSQFLNFWNKQDTLELESPSLTSTPV 478

Query: 373 ----TNVDTPLKGGLNTPLHESDFSGVTPQRQ--VVQTPNTVLSTPFR 414
                 V TPL     TPLH+   + VTP ++  +  TP+T   TPF+
Sbjct: 479 CSQKVVVTTPLHRD-KTPLHQKHAAFVTPDQKYSMDNTPHT--PTPFK 523



 Score = 70.5 bits (171), Expect = 6e-12
 Identities = 38/109 (34%), Positives = 61/109 (55%), Gaps = 4/109 (3%)

Query: 11  WRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEK 70
           W + EDE L+A V ++G+  W  +AS    ++ +QC+ RW   L+P + K  W++EE++K
Sbjct: 34  WTHEEDEQLRALVRQFGQQDWKFLASHFPNRTDQQCQYRWLRVLNPDLVKGPWTKEEDQK 93

Query: 71  LLHLAKLMPT-QWRTIAP-IIGRTAAQCLEHYEFLLDKAAQRD--NEEE 115
           ++ L K   T QW  IA  + GR   QC E +   L+   ++    EEE
Sbjct: 94  VIELVKKYGTKQWTLIAKHLKGRLGKQCRERWHNHLNPEVKKSCWTEEE 142


>gi|92859678 small nuclear RNA activating complex, polypeptide 4,
           190kDa [Homo sapiens]
          Length = 1469

 Score = 62.0 bits (149), Expect = 2e-09
 Identities = 36/103 (34%), Positives = 55/103 (53%), Gaps = 2/103 (1%)

Query: 6   IKGGVWRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSR 65
           +K G W   ED  L  AV KYG+  W +I   +  +S  QC+ R+   L  S+KK  W+ 
Sbjct: 399 LKKGYWAPEEDAKLLQAVAKYGEQDWFKIREEVPGRSDAQCRDRYLRRLHFSLKKGRWNL 458

Query: 66  EEEEKLLHL-AKLMPTQWRTIA-PIIGRTAAQCLEHYEFLLDK 106
           +EEE+L+ L  K     W  IA  +  R+ +QCL  ++ ++ K
Sbjct: 459 KEEEQLIELIEKYGVGHWAKIASELPHRSGSQCLSKWKIMMGK 501



 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 40/119 (33%), Positives = 56/119 (47%), Gaps = 9/119 (7%)

Query: 6   IKGGVWRNTEDEILKAAV--MKYGKN-QWSRIASLLHRKSAKQCKARWYEWLDPSIKKTE 62
           +K   W   ED +L   V  M+ G +  + RI   +  + + Q   RW + LDP +KK  
Sbjct: 344 LKRKEWTEEEDRMLTQLVQEMRVGSHIPYRRIVYYMEGRDSMQLIYRWTKSLDPGLKKGY 403

Query: 63  WSREEEEKLLH-LAKLMPTQWRTI-APIIGRTAAQCLEHY----EFLLDKAAQRDNEEE 115
           W+ EE+ KLL  +AK     W  I   + GR+ AQC + Y     F L K      EEE
Sbjct: 404 WAPEEDAKLLQAVAKYGEQDWFKIREEVPGRSDAQCRDRYLRRLHFSLKKGRWNLKEEE 462



 Score = 50.1 bits (118), Expect = 8e-06
 Identities = 35/100 (35%), Positives = 58/100 (58%), Gaps = 8/100 (8%)

Query: 29  NQWSRIASLLHR--KSAKQCKARWYEWLDPSIKKTEWSREEEEKLLHLAKLM-PTQWRTI 85
           + W +I+++     +SA++ +  W     PSI K EWSREEEE+L  +A      +W+ I
Sbjct: 261 HDWEKISNINFEGSRSAEEIRKFWQNSEHPSINKQEWSREEEERLQAIAAAHGHLEWQKI 320

Query: 86  APIIG--RTAAQCLEHYEFLLDKAAQRDNEEETTDDPRKL 123
           A  +G  R+A QCL+ ++   +KA +R  +E T ++ R L
Sbjct: 321 AEELGTSRSAFQCLQKFQ-QHNKALKR--KEWTEEEDRML 357



 Score = 40.0 bits (92), Expect = 0.009
 Identities = 22/69 (31%), Positives = 38/69 (55%), Gaps = 2/69 (2%)

Query: 11  WRNTEDEILKAAVMKYGKNQWSRIASLL-HRKSAKQCKARWYEWLDPSIKKTEWSREEEE 69
           W   E+E L+A    +G  +W +IA  L   +SA QC  + ++  + ++K+ EW+ EE+ 
Sbjct: 297 WSREEEERLQAIAAAHGHLEWQKIAEELGTSRSAFQCLQK-FQQHNKALKRKEWTEEEDR 355

Query: 70  KLLHLAKLM 78
            L  L + M
Sbjct: 356 MLTQLVQEM 364


>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
          Length = 843

 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 40/183 (21%), Positives = 86/183 (46%), Gaps = 21/183 (11%)

Query: 105 DKAAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQG 164
           D   ++  +E+  D  R+     + P P       + I+M+ED+ +++S   ++  +T  
Sbjct: 230 DSHPRKKKKEKKEDIFRRFPVAPLIPYPLITKEDINAIEMEEDKRDLISREISKFRDTHK 289

Query: 165 K----KAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKP 220
           K    K K++   +++E+ RR    ++ RE      E +++R+R+R  +   E   E+  
Sbjct: 290 KLEEEKGKKEKERQEIEKERRERERERERERERREREREREREREREKEKERERERER-- 347

Query: 221 ALGFYDTSEENYQALDADFRKLRQQDLDGE---------LRSEKEGRDRKKDKQHLKRKK 271
                D   +  +  D D  + R +D D E          RS ++ RDR+++++  +R++
Sbjct: 348 -----DRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERER-ERER 401

Query: 272 ESD 274
           E +
Sbjct: 402 ERE 404



 Score = 47.4 bits (111), Expect = 5e-05
 Identities = 61/265 (23%), Positives = 113/265 (42%), Gaps = 23/265 (8%)

Query: 105 DKAAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQG 164
           D+  +R+ E E   +  + +  E +   E +  R    D   D  E   +A  R      
Sbjct: 390 DREREREREREREREREREREREREREREREREREREKDKKRDREEDEEDAYER------ 443

Query: 165 KKAKRKAREKQLEEARRLA--ALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPAL 222
           +K +RK REK+     RL    +++R++ R    E +++ +R+R +   A+     K  L
Sbjct: 444 RKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAK---RLKEFL 500

Query: 223 GFYDTSEENYQALDADFRKLRQQDLDGELRSEKEGRDRKKDKQHLKRKKESDL------P 276
             YD   ++ +       + R +D + E+  E + RDRK++K+ L+  ++  L      P
Sbjct: 501 EDYDDDRDDPKYYRGSALQKRLRDREKEM--EADERDRKREKEELEEIRQRLLAEGHPDP 558

Query: 277 SAILQTSGVSEFTKKRSKLVLPAPQISDAELQEVVKVGQASEIARQTAEESGITNSASST 336
            A LQ     E  ++R   +   P+ S+ E +E  +  +  E   +  EE         T
Sbjct: 559 DAELQRM-EQEAERRRQPQIKQEPE-SEEEEEEKQEKEEKREEPMEEEEEPEQKPCLKPT 616

Query: 337 L--LSEYNVTNNSVALRTPRTPASQ 359
           L  +S     +++    TP TP  +
Sbjct: 617 LRPISSAPSVSSASGNATPNTPGDE 641



 Score = 38.5 bits (88), Expect = 0.025
 Identities = 38/167 (22%), Positives = 73/167 (43%), Gaps = 6/167 (3%)

Query: 109 QRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAK 168
           +R+ E E   +  + K  E +   E    R    + D D        R R  ++   K +
Sbjct: 322 RREREREREREREREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDR 381

Query: 169 RKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFYDTS 228
            ++REK  +  R     ++R   R    E +++R+R+R  +   E   EK       +  
Sbjct: 382 SRSREKSRDRERE----REREREREREREREREREREREREREREREREKDKKRDREEDE 437

Query: 229 EENYQALDADFRKLRQQDLDGELRSEK-EGRDRKKDKQHLKRKKESD 274
           E+ Y+    + RKLR+++   + R +  E R+RKK +++ K  +  +
Sbjct: 438 EDAYERRKLE-RKLREKEAAYQERLKNWEIRERKKTREYEKEAEREE 483


>gi|34878777 ring finger protein 20 [Homo sapiens]
          Length = 975

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 53/221 (23%), Positives = 99/221 (44%), Gaps = 15/221 (6%)

Query: 110 RDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKR 169
           + + E+  D+P +LKP   D + ++  ++    D +E + +   E R R    + ++ + 
Sbjct: 523 QSSTEDPKDEPAELKPDSEDLSSQSSASKASQEDANEIKSKRDEEERER-ERREKERERE 581

Query: 170 KAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFYDTSE 229
           + REK+ E  R    L++  + R +  + ++K K   G    AEI  + K  L     S+
Sbjct: 582 REREKEKEREREKQKLKESEKERDSAKD-KEKGKHDDGRKKEAEIIKQLKIELKKAQESQ 640

Query: 230 ENYQALDADFRKLRQQDLD------GELRSEKEGRDRK------KDKQHLKRKKESDLPS 277
           +  + L   +R   ++  D       E +S+ E  D +      +DK+  + KK +D   
Sbjct: 641 KEMKLLLDMYRSAPKEQRDKVQLMAAEKKSKAELEDLRQRLKDLEDKEKKENKKMAD-ED 699

Query: 278 AILQTSGVSEFTKKRSKLVLPAPQISDAELQEVVKVGQASE 318
           A+ +   V E  +   K +  A Q  +A L E+   GQA E
Sbjct: 700 ALRKIRAVEEQIEYLQKKLAMAKQEEEALLSEMDVTGQAFE 740



 Score = 31.2 bits (69), Expect = 4.0
 Identities = 51/289 (17%), Positives = 126/289 (43%), Gaps = 51/289 (17%)

Query: 105 DKAAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQG 164
           ++  +R+ E+E   + +KLK  E + +      +    D  + E E++ + +  L   Q 
Sbjct: 579 EREREREKEKEREREKQKLKESEKERDSAKDKEKGKHDDGRKKEAEIIKQLKIELKKAQE 638

Query: 165 KKAK--------RKAREKQLEEARRLAALQKRR------ELRAAGIEIQKKRKRKRGVDY 210
            + +        R A ++Q ++ + +AA +K +        R   +E ++K++ K+  D 
Sbjct: 639 SQKEMKLLLDMYRSAPKEQRDKVQLMAAEKKSKAELEDLRQRLKDLEDKEKKENKKMADE 698

Query: 211 NA---------EIPF-EKKPALGFYDTSEENYQALDADFRKLRQQDLDGELRSEKEGRDR 260
           +A         +I + +KK A+     +++  +AL      L + D+ G+   + + ++ 
Sbjct: 699 DALRKIRAVEEQIEYLQKKLAM-----AKQEEEAL------LSEMDVTGQAFEDMQEQNI 747

Query: 261 KKDKQHLKRKKESD--LPSAILQTSGVSEFTKKRSKLVLPAPQISDAELQEVVKVGQASE 318
           +   Q L+ K +++  L S  ++++ + +  K+  +      +++D  L    +V    +
Sbjct: 748 RL-MQQLREKDDANFKLMSERIKSNQIHKLLKEEKE------ELADQVLTLKTQVDAQLQ 800

Query: 319 IARQTAEESGITNSASSTLLSEYNVTNNSVALRTPRTPASQDRILQEAQ 367
           + R+  E+  +       L S        + LRT     ++ + ++ AQ
Sbjct: 801 VVRKLEEKEHL-------LQSNIGTGEKELGLRTQALEMNKRKAMEAAQ 842



 Score = 30.8 bits (68), Expect = 5.2
 Identities = 31/123 (25%), Positives = 57/123 (46%), Gaps = 16/123 (13%)

Query: 693 EKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQS---------RAMGLMK----QLNDLW 739
           +K  EI +  +  E K+A + +K+MK+LL  Y+S         + M   K    +L DL 
Sbjct: 620 KKEAEIIK-QLKIELKKAQESQKEMKLLLDMYRSAPKEQRDKVQLMAAEKKSKAELEDLR 678

Query: 740 DQIEQAHLELRTFEELKKHEDSAIPRRLECLKEDVQRQQEREKELQHRYADLLLEKETLK 799
            +++   LE +  +E KK  D    R++  ++E ++  Q++    +     LL E +   
Sbjct: 679 QRLKD--LEDKEKKENKKMADEDALRKIRAVEEQIEYLQKKLAMAKQEEEALLSEMDVTG 736

Query: 800 SKF 802
             F
Sbjct: 737 QAF 739


>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
          Length = 2817

 Score = 46.6 bits (109), Expect = 9e-05
 Identities = 48/217 (22%), Positives = 98/217 (45%), Gaps = 26/217 (11%)

Query: 109 QRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDE---DELEMLSEARARLANTQGK 165
           +R         P+ L      P+ +  P RP P    +   DE E+  + R + +     
Sbjct: 399 ERGTSSHLPPPPKLLAQQHPPPDRQAVPGRPGPFPSKQQVADEDEIWKQRRRQQSEISA- 457

Query: 166 KAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFY 225
            A  +AR+++ EE RR+   +K     AA  E  K+   K G+        EK+P     
Sbjct: 458 -AVERARKRREEEERRMEEQRK-----AACAEKLKRLDEKLGI-------LEKQP----- 499

Query: 226 DTSEENYQALDADFRKLRQQDLDGELRSEKEGRDRKKDKQHLKRKKESDLPSAILQTSGV 285
             S E  +  + +  + R+++L+ E   E+E ++R+KD++  +++KE +L     +   +
Sbjct: 500 --SPEEIREREREKEREREKELEKEQEQERE-KEREKDRER-QQEKEKELEKEQEKQREM 555

Query: 286 SEFTKKRSKLVLPAPQISDAELQEVVKVGQASEIARQ 322
            +  K+  +  L   +  + ELQ++ +  +  E+ ++
Sbjct: 556 EKERKQEKEKELERQKEKEKELQKMKEQEKECELEKE 592



 Score = 32.3 bits (72), Expect = 1.8
 Identities = 24/86 (27%), Positives = 44/86 (51%), Gaps = 4/86 (4%)

Query: 496 ENAEKELEEREIDDTYIEDAADVDARKQAIRDAERVKEMKRMHKAVQK-DLPRPSEVNET 554
           +  EKELE+ +     +E     +  K+  R  E+ KE+++M +  ++ +L +  E  E 
Sbjct: 539 QEKEKELEKEQEKQREMEKERKQEKEKELERQKEKEKELQKMKEQEKECELEKEREKLEE 598

Query: 555 ILRPL--NVEPPLTDLQKSEELIKKE 578
            + P   N+E P+ + Q+SE    KE
Sbjct: 599 KIEPREPNLE-PMVEKQESENSCNKE 623


>gi|58530840 desmoplakin isoform I [Homo sapiens]
          Length = 2871

 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 122/687 (17%), Positives = 265/687 (38%), Gaps = 89/687 (12%)

Query: 159  LANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKRGVD--------- 209
            L     ++++  AR KQ  E        K +E+     E Q++ KR+   +         
Sbjct: 1295 LKQVMQQRSEDNARHKQSLEEAAKTIQDKNKEIERLKAEFQEEAKRRWEYENELSKVRNN 1354

Query: 210  YNAEIPFEKKPALGFYDTSEENYQALDADFRKLRQQDLDGELRS----EKEGRDRKKDKQ 265
            Y+ EI   K      ++T     +         +++D  G         +E R   ++ +
Sbjct: 1355 YDEEIISLKNQ----FETEINITKTTIHQLTMQKEEDTSGYRAQIDNLTRENRSLSEEIK 1410

Query: 266  HLK----------RKKESDLPSAILQTSGVSEFTKKRSKLVLPAPQISDAELQEVVKVGQ 315
             LK          R+ E D+     Q +  SE ++++ +L +   Q++    +E V+  Q
Sbjct: 1411 RLKNTLTQTTENLRRVEEDIQQ---QKATGSEVSQRKQQLEVELRQVTQMRTEESVRYKQ 1467

Query: 316  ASEIARQTAEESGITNSASSTLLSEYNVTNNSVALRTPRTPASQDRILQEAQNLMALTNV 375
            + + A +T ++          L+ +   TN+   L        + +   +  N  A   +
Sbjct: 1468 SLDDAAKTIQDKNKEIERLKQLIDKE--TNDRKCLEDENARLQRVQYDLQKANSSATETI 1525

Query: 376  DTPLKGGLNTPLHESDFSGVTPQRQVVQTPNTVLSTPFRTPSNGAEGLTPRSGTTPKPVI 435
            +              D+  V+ +R V     T      +      + +        +   
Sbjct: 1526 NKLKVQEQELTRLRIDYERVSQERTVKDQDITRFQNSLKELQLQKQKVEEELNRLKRTAS 1585

Query: 436  NSTPGRTPLRDKLNINPEDGMADYSDPSYVKQMERESREHLRLGLLGLPAPKNDFEIVLP 495
              +  R  L ++L     +GM             R S +   + +  L        IV  
Sbjct: 1586 EDSCKRKKLEEEL-----EGM-------------RRSLKEQAIKITNLTQQLEQASIVKK 1627

Query: 496  ENAEKELEEREIDDTYIED-----------AADVDA-RKQAIRDAERVKEMKRMHKAVQK 543
             + +   ++R++ D ++ +           +++V+A R+Q +++ E VK+    ++  QK
Sbjct: 1628 RSEDDLRQQRDVLDGHLREKQRTQEELRRLSSEVEALRRQLLQEQESVKQAHLRNEHFQK 1687

Query: 544  DLPRPSE-VNETILRPLNVEPPLTDLQKSEELIKKEMITM-LHYDLLHHPYEPSGNKKGK 601
             +   S  +NE+ +    ++    +L K   ++++E+  + L YD L      + + K  
Sbjct: 1688 AIEDKSRSLNESKIEIERLQSLTENLTKEHLMLEEELRNLRLEYDDLRRGRSEADSDKNA 1747

Query: 602  TVGFGTNNSEHITYLEHNPYEKFSKE----ELKKAQDVLVQEMEVV-KQGMSHGELSSEA 656
            T+       E  + L+ +       +    +L++ ++ L QE+E   KQ +       E+
Sbjct: 1748 TI------LELRSQLQISNNRTLELQGLINDLQRERENLRQEIEKFQKQALEASNRIQES 1801

Query: 657  YNQVWEECYSQVLYLPGQSRYTRANLASKKDRIESLEKRLEINRGHMTTEAKRAAKMEKK 716
             NQ      +QV+            L   K R++ LE   E+NR   T EA      E +
Sbjct: 1802 KNQC-----TQVVQERESLLVKIKVLEQDKARLQRLED--ELNRAKSTLEA------ETR 1848

Query: 717  MKILLGGYQSRAMGLMKQLNDLWDQIEQAHLELRTFEELKKHEDSAIPRRLECLKEDVQR 776
            +K  L   + +    + Q    + + E+A  ++ +  E  + E +++   +E L+ +++R
Sbjct: 1849 VKQRLECEKQQIQNDLNQWKTQYSRKEEAIRKIESEREKSEREKNSLRSEIERLQAEIKR 1908

Query: 777  QQER-EKELQHRYADLLLEKETLKSKF 802
             +ER  ++L+    +   + ET +S++
Sbjct: 1909 IEERCRRKLEDSTRETQSQLETERSRY 1935


>gi|71061468 centromere protein E [Homo sapiens]
          Length = 2701

 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 41/177 (23%), Positives = 85/177 (48%), Gaps = 27/177 (15%)

Query: 626  KEELKKAQDVLVQEMEVVKQGMSH---GELSSEAYNQVWEECYSQVLYLPGQSRYTRANL 682
            K++L++ Q+VL  E + +K+ +       L +E   +V   C  +      +    R NL
Sbjct: 1444 KDDLQRLQEVLQSESDQLKENIKEIVAKHLETEEELKVAHCCLKEQEETINE---LRVNL 1500

Query: 683  ASKKDRIESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQLNDLWDQI 742
            + K+  I +++K+LE     +  + +   + E++  I             KQ++++ +++
Sbjct: 1501 SEKETEISTIQKQLEAINDKLQNKIQEIYEKEEQFNI-------------KQISEVQEKV 1547

Query: 743  EQAHLELRTFEELKKHEDSAIPRRLECLKEDVQRQQEREKELQHRYADLLLEKETLK 799
                 EL+ F+E +K +DSA+      + E   R QE ++E+Q     ++ EKE +K
Sbjct: 1548 N----ELKQFKEHRKAKDSALQSIESKMLELTNRLQESQEEIQ----IMIKEKEEMK 1596



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 66/335 (19%), Positives = 126/335 (37%), Gaps = 34/335 (10%)

Query: 496  ENAEKELEEREIDDTYIEDAADVDARKQAIRDAERVKEMKRMHKAVQKDLPRPSEVNETI 555
            EN + EL+ +E+   ++E    ++  ++   + E VK + +  K V K+L +  E     
Sbjct: 1161 ENLKNELKNKELTLEHMETER-LELAQKLNENYEEVKSITKERK-VLKELQKSFETERDH 1218

Query: 556  LRPLNVEPPLTDLQKSEELIKKEMITMLHYDLLHHPYEPSGNKKGKTVGFGTNNSEHITY 615
            LR    E   T LQ  EEL    +    H + +         K  + +        H   
Sbjct: 1219 LRGYIREIEATGLQTKEELKIAHIHLKEHQETIDELRRSVSEKTAQIINTQDLEKSHTKL 1278

Query: 616  LEHNPYEKFSKEELKKAQDV-----------LVQEMEVVKQGMSHGELSSEAY--NQVWE 662
             E  P     +E L   ++V           L+ E    K   +   +  E    N+ ++
Sbjct: 1279 QEEIPVLHEEQELLPNVKEVSETQETMNELELLTEQSTTKDSTTLARIEMERLRLNEKFQ 1338

Query: 663  ECYSQVLYLPGQ------------------SRYTRANLASKKDRIESLEKRLEIN-RGHM 703
            E   ++  L  +                    + R  LA  ++     E+ L +  + + 
Sbjct: 1339 ESQEEIKSLTKERDNLKTIKEALEVKHDQLKEHIRETLAKIQESQSKQEQSLNMKEKDNE 1398

Query: 704  TTEAKRAAKMEKKMKILLGGYQSRAMGLMKQLNDLWDQIEQAHLELRTFEELKKHEDSAI 763
            TT+     +  K     L   +   +GL K+L +  D+++    E    + L++   S  
Sbjct: 1399 TTKIVSEMEQFKPKDSALLRIEIEMLGLSKRLQESHDEMKSVAKEKDDLQRLQEVLQSES 1458

Query: 764  PRRLECLKEDVQRQQEREKELQHRYADLLLEKETL 798
             +  E +KE V +  E E+EL+  +  L  ++ET+
Sbjct: 1459 DQLKENIKEIVAKHLETEEELKVAHCCLKEQEETI 1493



 Score = 38.1 bits (87), Expect = 0.033
 Identities = 70/340 (20%), Positives = 144/340 (42%), Gaps = 53/340 (15%)

Query: 487 KNDFEIVLPENAEKELEEREIDDTYIEDAADV-------DARKQAIRDAERVKEMKRMHK 539
           K +   +  EN E + + +E+  TY +   D+       +A+K+   D E  KE++    
Sbjct: 638 KRESAFLRSENLELKEKMKELATTYKQMENDIQLYQSQLEAKKKMQVDLE--KELQSAFN 695

Query: 540 AVQKDLPR-PSEVNETILRPLNVEPPLTDLQKS-------EELIKKEMITMLHYDLLHHP 591
            + K       +V + +L  L +E  +TDLQK         E +++E+I +     L   
Sbjct: 696 EITKLTSLIDGKVPKDLLCNLELEGKITDLQKELNKEVEENEALREEVILLSELKSLPSE 755

Query: 592 YEPSGNKKGKTVGFGTNNSEHITYLEHNPYEKFSKEELKKAQ-DVLVQEMEVVKQGMSHG 650
            E    +  K +    + SE +  +     + FS+   K+++   L++E+   K  ++  
Sbjct: 756 VE----RLRKEI---QDKSEELHIITSEKDKLFSEVVHKESRVQGLLEEIGKTKDDLATT 808

Query: 651 ELSSEAYNQVW----------EECYSQVLYLPGQSRYTRANLASKKDRIESLEKRLEINR 700
           + + ++ +Q +          E+ Y  VL    +      NL+ +  + +S    L+   
Sbjct: 809 QSNYKSTDQEFQNFKTLHMDFEQKYKMVLEENERMNQEIVNLSKEAQKFDSSLGALKTEL 868

Query: 701 GHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQLNDLWDQIEQAHLELRTFEELKKHED 760
            + T E +     EK  ++     Q R    + ++  L +Q+E     L+T E     E 
Sbjct: 869 SYKTQELQ-----EKTREV-----QER----LNEMEQLKEQLENRDSTLQTVER----EK 910

Query: 761 SAIPRRLECLKEDVQRQQEREKELQHRYADLLLEKETLKS 800
           + I  +L+   E+V+   + + +L+     L +E++ LKS
Sbjct: 911 TLITEKLQQTLEEVKTLTQEKDDLKQLQESLQIERDQLKS 950



 Score = 32.7 bits (73), Expect = 1.4
 Identities = 33/179 (18%), Positives = 80/179 (44%), Gaps = 15/179 (8%)

Query: 625  SKEELKKAQDVLVQEMEVVKQGMSH-----GELSSEAYNQVWEECYSQVLYLPGQSRYTR 679
            ++EEL+   D L ++ E+V Q  +H     GELS         E   ++     Q +  +
Sbjct: 1083 NQEELRLLGDELKKQQEIVAQEKNHAIKKEGELSRTCDRLA--EVEEKLKEKSQQLQEKQ 1140

Query: 680  ANLASKKDRIESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQLNDLW 739
              L + ++ +  ++K++         E +      K  ++ L   ++  + L ++LN+ +
Sbjct: 1141 QQLLNVQEEMSEMQKKI--------NEIENLKNELKNKELTLEHMETERLELAQKLNENY 1192

Query: 740  DQIEQAHLELRTFEELKKHEDSAIPRRLECLKEDVQRQQEREKELQHRYADLLLEKETL 798
            ++++    E +  +EL+K  ++        ++E      + ++EL+  +  L   +ET+
Sbjct: 1193 EEVKSITKERKVLKELQKSFETERDHLRGYIREIEATGLQTKEELKIAHIHLKEHQETI 1251



 Score = 31.6 bits (70), Expect = 3.1
 Identities = 43/185 (23%), Positives = 87/185 (47%), Gaps = 22/185 (11%)

Query: 98   EHYEFLLDKAAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEAR- 156
            E+ E +     +RDN     ++  KL+  ++  + +   AR         +LE+  E + 
Sbjct: 1879 ENLEEMKSVMKERDNLRRV-EETLKLERDQLKESLQETKAR---------DLEIQQELKT 1928

Query: 157  ARLANTQGKKAKRKAREKQLEEARRLAALQK-----RRELRAAGIEIQKKRKRKRGVDYN 211
            AR+ + + K+   K REK  E+  +++ +QK     + EL+    E+QKK  +   V  +
Sbjct: 1929 ARMLSKEHKETVDKLREKISEKTIQISDIQKDLDKSKDELQKKIQELQKKELQLLRVKED 1988

Query: 212  AEIPFEKKPALGFYDTSEENYQALDADFRKLRQQD--LDGEL-RSEKEGRDRKKDKQHLK 268
              +  +K   +   +  ++ ++A +   + +R  +  L  +L  S +E R   K++  L+
Sbjct: 1989 VNMSHKK---INEMEQLKKQFEAQNLSMQSVRMDNFQLTKKLHESLEEIRIVAKERDELR 2045

Query: 269  RKKES 273
            R KES
Sbjct: 2046 RIKES 2050


>gi|31982906 cingulin-like 1 [Homo sapiens]
          Length = 1302

 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 98/542 (18%), Positives = 210/542 (38%), Gaps = 79/542 (14%)

Query: 269 RKKESDLPSAILQTSGVSEFTKKRSKLVLPAPQI-SDAELQEVVKVGQASEIARQTAEES 327
           R  + ++   +L+T G  E T      V+ AP + + ++ +E VK   A+ + +  A  +
Sbjct: 460 RPPQPNIDGKVLETEGSQEST------VIRAPSLGAQSKKEEEVKTATATLMLQNRATAT 513

Query: 328 GITNSASSTLLSEYNVTNNSVALRTPRTPASQDRILQEAQNLMALTNVDTPLKGGLNTPL 387
              + A    +  +   +N        T A+ D +L+  Q L   TN +T  K  L   L
Sbjct: 514 SPDSGAKKISVKTFPSASN--------TQATPD-LLKGQQELTQQTNEETA-KQILYNYL 563

Query: 388 HESDFSGVTPQRQVVQTPNTVLSTPFRTPSNGAEGLTPRSGTTPKPVINSTPGRTPLRDK 447
            E         ++ V      + T     +  A+G      +T     +        + K
Sbjct: 564 KEGSTDNDDATKRKVNLVFEKIQTLKSRAAGSAQGNNQACNST-----SEVKDLLEQKSK 618

Query: 448 LNINPEDGMADYSDPSYVKQMERESREHLRLGLLGLPAPKNDFEIVLPENAEKELEEREI 507
           L I   +           +Q  +E RE +R  L  L +  N+ ++      ++ LEE E 
Sbjct: 619 LTIEVAELQRQLQLEVKNQQNIKEERERMRANLEELRSQHNE-KVEENSTLQQRLEESEG 677

Query: 508 D-----DTYIEDAADVDARKQAIRDAERVKEMKRMHKAVQ-----KDLPRPSEVNETILR 557
           +     +   +   + +  +  IRD +   ++  MH  +      +D  + + + E +  
Sbjct: 678 ELRKNLEELFQVKMEREQHQTEIRDLQ--DQLSEMHDELDSAKRSEDREKGALIEELLQA 735

Query: 558 PLNVEPPLTDLQKSEELIKKEMITMLHYDLLHHPYEPSGNKKGKTVGFGTNNSEHITYLE 617
             +++  L   ++ E+L++K                                   +T L+
Sbjct: 736 KQDLQDLLIAKEEQEDLLRKR-------------------------------ERELTALK 764

Query: 618 HNPYEKFSKEELKKAQDVLVQEMEVVKQGMSHGELSSEAYNQVWEECYSQVLYLPGQSRY 677
               E+ S  +         QEM+ +K+     +   +A  +  EE    V  L  +S  
Sbjct: 765 GALKEEVSSHD---------QEMDKLKEQY---DAELQALRESVEEATKNVEVLASRSNT 812

Query: 678 TRANLASKKDRIESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQLND 737
           +  + A  + R++ L++  E  +G      +R A+++++++ L G  +++A   +K+   
Sbjct: 813 SEQDQAGTEMRVKLLQEENEKLQGRSEELERRVAQLQRQIEDLKGD-EAKAKETLKKYEG 871

Query: 738 LWDQIEQAHLELRTFEELKKHEDSAIPRRLECLKEDVQRQQEREKELQHRYADLLLEKET 797
              Q+E+A +  R  E+       A+   LE  + ++ +  + +K+L  +  +   +KE 
Sbjct: 872 EIRQLEEALVHARKEEKEAVSARRALENELEAAQGNLSQTTQEQKQLSEKLKEESEQKEQ 931

Query: 798 LK 799
           L+
Sbjct: 932 LR 933



 Score = 35.0 bits (79), Expect = 0.28
 Identities = 31/129 (24%), Positives = 57/129 (44%), Gaps = 19/129 (14%)

Query: 679 RANLASKKDRIESLEKRLEINRGHMTTEAKRA--AKMEKKMKILLGGYQSRAMGLMKQLN 736
           R+    K +   +L++RLE + G +    +     KME++                 ++ 
Sbjct: 655 RSQHNEKVEENSTLQQRLEESEGELRKNLEELFQVKMEREQH-------------QTEIR 701

Query: 737 DLWDQIEQAHLELRTFEELKKHEDSAIPRRLECLKEDVQ----RQQEREKELQHRYADLL 792
           DL DQ+ + H EL + +  +  E  A+   L   K+D+Q     ++E+E  L+ R  +L 
Sbjct: 702 DLQDQLSEMHDELDSAKRSEDREKGALIEELLQAKQDLQDLLIAKEEQEDLLRKRERELT 761

Query: 793 LEKETLKSK 801
             K  LK +
Sbjct: 762 ALKGALKEE 770


>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
          Length = 4547

 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 60/285 (21%), Positives = 110/285 (38%), Gaps = 27/285 (9%)

Query: 91   RTAAQCLEHYEFLLDKAAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELE 150
            R   + +   E  +D   Q+ + +E     R+    EI        A        E+E+ 
Sbjct: 1396 RMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIR 1455

Query: 151  M----LSEARARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKR 206
            +    L     +    +G+    +AR ++ E  +R A  Q+  E     ++ + +RKR+ 
Sbjct: 1456 VVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQA--QEEAERLRRQVQDESQRKRQA 1513

Query: 207  GVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKLRQQDLDGELRSEKEGRDRKKDKQH 266
             V+  + +  E + A        E  +AL A         L+ ELR + E  +R+  +  
Sbjct: 1514 EVELASRVKAEAEAA-------REKQRALQA---------LE-ELRLQAEEAERRLRQAE 1556

Query: 267  LKRKKESDLPSAILQTSGVSEFTKKRSKLVLPAPQISDAELQEVVKVGQ----ASEIARQ 322
            ++R ++  +     Q S  +E   KR+       Q+  +  +E V V Q    A   A+Q
Sbjct: 1557 VERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQ 1616

Query: 323  TAEESGITNSASSTLLSEYNVTNNSVALRTPRTPASQDRILQEAQ 367
             AE       A   L       N ++ LR      +Q + L +A+
Sbjct: 1617 QAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAE 1661



 Score = 37.4 bits (85), Expect = 0.056
 Identities = 137/772 (17%), Positives = 288/772 (37%), Gaps = 105/772 (13%)

Query: 68   EEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLL------DKAAQRDNEEETTDDPR 121
            EE+L  L K   ++      ++  T  Q  +  E +L      +KAA    E E      
Sbjct: 1892 EERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELE------ 1945

Query: 122  KLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARR 181
             L+ G I  N E      +  +++      L+    R      ++ ++    ++    +R
Sbjct: 1946 -LELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQR 2004

Query: 182  LAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFR- 240
             AAL++   L+A   E ++ R+R            E++ A       E   + L A+ + 
Sbjct: 2005 KAALEEVERLKAKVEEARRLRERA-----------EQESARQLQLAQEAAQKRLQAEEKA 2053

Query: 241  -----KLRQQDLDGELRSEKEGRDRKKDKQHLKRKKESDLPSAILQTSGVSEFTKKRSKL 295
                 + ++Q+L   L+ E+   D+ + +    R+   +   A +Q    +  ++++ + 
Sbjct: 2054 HAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEE 2113

Query: 296  VLPAPQISDAELQEVVKVGQASEIARQTAEESGITNS-ASSTLLSEYNVTNNSVALRTPR 354
                 Q ++ + Q   +   A+E  R+ AE+     + A    L +    +   A     
Sbjct: 2114 AERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAAD---AEMEKH 2170

Query: 355  TPASQDRILQEAQNLMALTNVDTPL------KGGLNTPLHESDFSGVTPQRQVVQTPNTV 408
               ++  + Q+AQ    LT +   L      K  L+  L           RQ  Q    +
Sbjct: 2171 KKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEEL 2230

Query: 409  LSTPFRTPSNGAEGLTPRSGTTPKPVINSTPGRTPLRDKLNINPEDGMADYSDPSYVKQM 468
             S   R        L  R     + +I        LRDK N                ++M
Sbjct: 2231 FSV--RVQMEELSKLKARIEAENRALI--------LRDKDN-------TQRFLQEEAEKM 2273

Query: 469  ERESREHLRLGLLGLPAPKNDFEIVLPENAEKEL-EEREIDDTYIEDAADVDARKQAIRD 527
            ++ + E  RL +    A +      L + AE++L ++R + +  +++      + QA+++
Sbjct: 2274 KQVAEEAARLSVAAQEAAR------LRQLAEEDLAQQRALAEKMLKE------KMQAVQE 2321

Query: 528  AERVKE----MKRMHKAVQKDLPRPSEVNETILRPLNVEPP------------LTDLQKS 571
            A R+K     +++  +  Q+   R  E  E + + L  E                ++   
Sbjct: 2322 ATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAE 2381

Query: 572  EELIKKEMITMLHYDLLHHPYEPSGNKKGKTVGFGTNNSEHITYLE---------HNPYE 622
             E +K  +  M               K+ + +G   + +E  T  +              
Sbjct: 2382 AERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQS 2441

Query: 623  KFSKEELKKAQDVLVQEMEVVKQGMSHGELSSEAYNQVWEECYSQVLYLPGQSRYTRANL 682
                E L++A   L +E E ++Q     +L SE    V +E   Q      QS  +  + 
Sbjct: 2442 DHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDS 2501

Query: 683  ASKKDR-IESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQL----ND 737
              +++R IE  + +LE        +A++  + +++ +  +   + R +  M++     ++
Sbjct: 2502 LLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHE 2561

Query: 738  LWDQIEQAHLELRTFEELKKHEDSAIPRRLECLKEDVQRQQEREKELQHRYA 789
              + + +   EL+  E+ ++ ++  +    + L+E +Q  +E     QHR A
Sbjct: 2562 AEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEE-----QHRAA 2608



 Score = 34.3 bits (77), Expect = 0.47
 Identities = 43/188 (22%), Positives = 87/188 (46%), Gaps = 16/188 (8%)

Query: 148  ELEMLSEARARLANTQGKKAKRKAR-----EKQLEEARRLAALQKRRELRAAGIEIQKKR 202
            E E   E   R A  +GK  ++  R     E++LE+ R+LA    ++ L A    I+ + 
Sbjct: 1661 EAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRA 1720

Query: 203  KRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKLRQQD---LDGELRSEKEGRD 259
            + ++G      +  E          + +  Q L+A+  K+R +    L  + R+E+E R 
Sbjct: 1721 ETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRS 1780

Query: 260  -RKKDKQHLKRK--KESDLPSAILQTSGVSEFTKKRSKLVL--PAPQISDAE---LQEVV 311
              +K KQ L+ +  +  +L     +   ++E  K++ +L     A Q ++AE    +++ 
Sbjct: 1781 TSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLA 1840

Query: 312  KVGQASEI 319
             +G+A+ +
Sbjct: 1841 AIGEATRL 1848


>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
          Length = 4551

 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 60/285 (21%), Positives = 110/285 (38%), Gaps = 27/285 (9%)

Query: 91   RTAAQCLEHYEFLLDKAAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELE 150
            R   + +   E  +D   Q+ + +E     R+    EI        A        E+E+ 
Sbjct: 1400 RMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIR 1459

Query: 151  M----LSEARARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKR 206
            +    L     +    +G+    +AR ++ E  +R A  Q+  E     ++ + +RKR+ 
Sbjct: 1460 VVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQA--QEEAERLRRQVQDESQRKRQA 1517

Query: 207  GVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKLRQQDLDGELRSEKEGRDRKKDKQH 266
             V+  + +  E + A        E  +AL A         L+ ELR + E  +R+  +  
Sbjct: 1518 EVELASRVKAEAEAA-------REKQRALQA---------LE-ELRLQAEEAERRLRQAE 1560

Query: 267  LKRKKESDLPSAILQTSGVSEFTKKRSKLVLPAPQISDAELQEVVKVGQ----ASEIARQ 322
            ++R ++  +     Q S  +E   KR+       Q+  +  +E V V Q    A   A+Q
Sbjct: 1561 VERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQ 1620

Query: 323  TAEESGITNSASSTLLSEYNVTNNSVALRTPRTPASQDRILQEAQ 367
             AE       A   L       N ++ LR      +Q + L +A+
Sbjct: 1621 QAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAE 1665



 Score = 37.4 bits (85), Expect = 0.056
 Identities = 137/772 (17%), Positives = 288/772 (37%), Gaps = 105/772 (13%)

Query: 68   EEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLL------DKAAQRDNEEETTDDPR 121
            EE+L  L K   ++      ++  T  Q  +  E +L      +KAA    E E      
Sbjct: 1896 EERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELE------ 1949

Query: 122  KLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARR 181
             L+ G I  N E      +  +++      L+    R      ++ ++    ++    +R
Sbjct: 1950 -LELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQR 2008

Query: 182  LAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFR- 240
             AAL++   L+A   E ++ R+R            E++ A       E   + L A+ + 
Sbjct: 2009 KAALEEVERLKAKVEEARRLRERA-----------EQESARQLQLAQEAAQKRLQAEEKA 2057

Query: 241  -----KLRQQDLDGELRSEKEGRDRKKDKQHLKRKKESDLPSAILQTSGVSEFTKKRSKL 295
                 + ++Q+L   L+ E+   D+ + +    R+   +   A +Q    +  ++++ + 
Sbjct: 2058 HAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEE 2117

Query: 296  VLPAPQISDAELQEVVKVGQASEIARQTAEESGITNS-ASSTLLSEYNVTNNSVALRTPR 354
                 Q ++ + Q   +   A+E  R+ AE+     + A    L +    +   A     
Sbjct: 2118 AERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAAD---AEMEKH 2174

Query: 355  TPASQDRILQEAQNLMALTNVDTPL------KGGLNTPLHESDFSGVTPQRQVVQTPNTV 408
               ++  + Q+AQ    LT +   L      K  L+  L           RQ  Q    +
Sbjct: 2175 KKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEEL 2234

Query: 409  LSTPFRTPSNGAEGLTPRSGTTPKPVINSTPGRTPLRDKLNINPEDGMADYSDPSYVKQM 468
             S   R        L  R     + +I        LRDK N                ++M
Sbjct: 2235 FSV--RVQMEELSKLKARIEAENRALI--------LRDKDN-------TQRFLQEEAEKM 2277

Query: 469  ERESREHLRLGLLGLPAPKNDFEIVLPENAEKEL-EEREIDDTYIEDAADVDARKQAIRD 527
            ++ + E  RL +    A +      L + AE++L ++R + +  +++      + QA+++
Sbjct: 2278 KQVAEEAARLSVAAQEAAR------LRQLAEEDLAQQRALAEKMLKE------KMQAVQE 2325

Query: 528  AERVKE----MKRMHKAVQKDLPRPSEVNETILRPLNVEPP------------LTDLQKS 571
            A R+K     +++  +  Q+   R  E  E + + L  E                ++   
Sbjct: 2326 ATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAE 2385

Query: 572  EELIKKEMITMLHYDLLHHPYEPSGNKKGKTVGFGTNNSEHITYLE---------HNPYE 622
             E +K  +  M               K+ + +G   + +E  T  +              
Sbjct: 2386 AERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQS 2445

Query: 623  KFSKEELKKAQDVLVQEMEVVKQGMSHGELSSEAYNQVWEECYSQVLYLPGQSRYTRANL 682
                E L++A   L +E E ++Q     +L SE    V +E   Q      QS  +  + 
Sbjct: 2446 DHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDS 2505

Query: 683  ASKKDR-IESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQL----ND 737
              +++R IE  + +LE        +A++  + +++ +  +   + R +  M++     ++
Sbjct: 2506 LLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHE 2565

Query: 738  LWDQIEQAHLELRTFEELKKHEDSAIPRRLECLKEDVQRQQEREKELQHRYA 789
              + + +   EL+  E+ ++ ++  +    + L+E +Q  +E     QHR A
Sbjct: 2566 AEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEE-----QHRAA 2612



 Score = 34.3 bits (77), Expect = 0.47
 Identities = 43/188 (22%), Positives = 87/188 (46%), Gaps = 16/188 (8%)

Query: 148  ELEMLSEARARLANTQGKKAKRKAR-----EKQLEEARRLAALQKRRELRAAGIEIQKKR 202
            E E   E   R A  +GK  ++  R     E++LE+ R+LA    ++ L A    I+ + 
Sbjct: 1665 EAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRA 1724

Query: 203  KRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKLRQQD---LDGELRSEKEGRD 259
            + ++G      +  E          + +  Q L+A+  K+R +    L  + R+E+E R 
Sbjct: 1725 ETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRS 1784

Query: 260  -RKKDKQHLKRK--KESDLPSAILQTSGVSEFTKKRSKLVL--PAPQISDAE---LQEVV 311
              +K KQ L+ +  +  +L     +   ++E  K++ +L     A Q ++AE    +++ 
Sbjct: 1785 TSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLA 1844

Query: 312  KVGQASEI 319
             +G+A+ +
Sbjct: 1845 AIGEATRL 1852


>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
          Length = 4547

 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 60/285 (21%), Positives = 110/285 (38%), Gaps = 27/285 (9%)

Query: 91   RTAAQCLEHYEFLLDKAAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELE 150
            R   + +   E  +D   Q+ + +E     R+    EI        A        E+E+ 
Sbjct: 1396 RMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIR 1455

Query: 151  M----LSEARARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKR 206
            +    L     +    +G+    +AR ++ E  +R A  Q+  E     ++ + +RKR+ 
Sbjct: 1456 VVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQA--QEEAERLRRQVQDESQRKRQA 1513

Query: 207  GVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKLRQQDLDGELRSEKEGRDRKKDKQH 266
             V+  + +  E + A        E  +AL A         L+ ELR + E  +R+  +  
Sbjct: 1514 EVELASRVKAEAEAA-------REKQRALQA---------LE-ELRLQAEEAERRLRQAE 1556

Query: 267  LKRKKESDLPSAILQTSGVSEFTKKRSKLVLPAPQISDAELQEVVKVGQ----ASEIARQ 322
            ++R ++  +     Q S  +E   KR+       Q+  +  +E V V Q    A   A+Q
Sbjct: 1557 VERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQ 1616

Query: 323  TAEESGITNSASSTLLSEYNVTNNSVALRTPRTPASQDRILQEAQ 367
             AE       A   L       N ++ LR      +Q + L +A+
Sbjct: 1617 QAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAE 1661



 Score = 37.4 bits (85), Expect = 0.056
 Identities = 137/772 (17%), Positives = 288/772 (37%), Gaps = 105/772 (13%)

Query: 68   EEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLL------DKAAQRDNEEETTDDPR 121
            EE+L  L K   ++      ++  T  Q  +  E +L      +KAA    E E      
Sbjct: 1892 EERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELE------ 1945

Query: 122  KLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARR 181
             L+ G I  N E      +  +++      L+    R      ++ ++    ++    +R
Sbjct: 1946 -LELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQR 2004

Query: 182  LAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFR- 240
             AAL++   L+A   E ++ R+R            E++ A       E   + L A+ + 
Sbjct: 2005 KAALEEVERLKAKVEEARRLRERA-----------EQESARQLQLAQEAAQKRLQAEEKA 2053

Query: 241  -----KLRQQDLDGELRSEKEGRDRKKDKQHLKRKKESDLPSAILQTSGVSEFTKKRSKL 295
                 + ++Q+L   L+ E+   D+ + +    R+   +   A +Q    +  ++++ + 
Sbjct: 2054 HAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEE 2113

Query: 296  VLPAPQISDAELQEVVKVGQASEIARQTAEESGITNS-ASSTLLSEYNVTNNSVALRTPR 354
                 Q ++ + Q   +   A+E  R+ AE+     + A    L +    +   A     
Sbjct: 2114 AERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAAD---AEMEKH 2170

Query: 355  TPASQDRILQEAQNLMALTNVDTPL------KGGLNTPLHESDFSGVTPQRQVVQTPNTV 408
               ++  + Q+AQ    LT +   L      K  L+  L           RQ  Q    +
Sbjct: 2171 KKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEEL 2230

Query: 409  LSTPFRTPSNGAEGLTPRSGTTPKPVINSTPGRTPLRDKLNINPEDGMADYSDPSYVKQM 468
             S   R        L  R     + +I        LRDK N                ++M
Sbjct: 2231 FSV--RVQMEELSKLKARIEAENRALI--------LRDKDN-------TQRFLQEEAEKM 2273

Query: 469  ERESREHLRLGLLGLPAPKNDFEIVLPENAEKEL-EEREIDDTYIEDAADVDARKQAIRD 527
            ++ + E  RL +    A +      L + AE++L ++R + +  +++      + QA+++
Sbjct: 2274 KQVAEEAARLSVAAQEAAR------LRQLAEEDLAQQRALAEKMLKE------KMQAVQE 2321

Query: 528  AERVKE----MKRMHKAVQKDLPRPSEVNETILRPLNVEPP------------LTDLQKS 571
            A R+K     +++  +  Q+   R  E  E + + L  E                ++   
Sbjct: 2322 ATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAE 2381

Query: 572  EELIKKEMITMLHYDLLHHPYEPSGNKKGKTVGFGTNNSEHITYLE---------HNPYE 622
             E +K  +  M               K+ + +G   + +E  T  +              
Sbjct: 2382 AERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQS 2441

Query: 623  KFSKEELKKAQDVLVQEMEVVKQGMSHGELSSEAYNQVWEECYSQVLYLPGQSRYTRANL 682
                E L++A   L +E E ++Q     +L SE    V +E   Q      QS  +  + 
Sbjct: 2442 DHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDS 2501

Query: 683  ASKKDR-IESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQL----ND 737
              +++R IE  + +LE        +A++  + +++ +  +   + R +  M++     ++
Sbjct: 2502 LLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHE 2561

Query: 738  LWDQIEQAHLELRTFEELKKHEDSAIPRRLECLKEDVQRQQEREKELQHRYA 789
              + + +   EL+  E+ ++ ++  +    + L+E +Q  +E     QHR A
Sbjct: 2562 AEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEE-----QHRAA 2608



 Score = 34.3 bits (77), Expect = 0.47
 Identities = 43/188 (22%), Positives = 87/188 (46%), Gaps = 16/188 (8%)

Query: 148  ELEMLSEARARLANTQGKKAKRKAR-----EKQLEEARRLAALQKRRELRAAGIEIQKKR 202
            E E   E   R A  +GK  ++  R     E++LE+ R+LA    ++ L A    I+ + 
Sbjct: 1661 EAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRA 1720

Query: 203  KRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKLRQQD---LDGELRSEKEGRD 259
            + ++G      +  E          + +  Q L+A+  K+R +    L  + R+E+E R 
Sbjct: 1721 ETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRS 1780

Query: 260  -RKKDKQHLKRK--KESDLPSAILQTSGVSEFTKKRSKLVL--PAPQISDAE---LQEVV 311
              +K KQ L+ +  +  +L     +   ++E  K++ +L     A Q ++AE    +++ 
Sbjct: 1781 TSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLA 1840

Query: 312  KVGQASEI 319
             +G+A+ +
Sbjct: 1841 AIGEATRL 1848


>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
          Length = 4515

 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 60/285 (21%), Positives = 110/285 (38%), Gaps = 27/285 (9%)

Query: 91   RTAAQCLEHYEFLLDKAAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELE 150
            R   + +   E  +D   Q+ + +E     R+    EI        A        E+E+ 
Sbjct: 1364 RMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIR 1423

Query: 151  M----LSEARARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKR 206
            +    L     +    +G+    +AR ++ E  +R A  Q+  E     ++ + +RKR+ 
Sbjct: 1424 VVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQA--QEEAERLRRQVQDESQRKRQA 1481

Query: 207  GVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKLRQQDLDGELRSEKEGRDRKKDKQH 266
             V+  + +  E + A        E  +AL A         L+ ELR + E  +R+  +  
Sbjct: 1482 EVELASRVKAEAEAA-------REKQRALQA---------LE-ELRLQAEEAERRLRQAE 1524

Query: 267  LKRKKESDLPSAILQTSGVSEFTKKRSKLVLPAPQISDAELQEVVKVGQ----ASEIARQ 322
            ++R ++  +     Q S  +E   KR+       Q+  +  +E V V Q    A   A+Q
Sbjct: 1525 VERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQ 1584

Query: 323  TAEESGITNSASSTLLSEYNVTNNSVALRTPRTPASQDRILQEAQ 367
             AE       A   L       N ++ LR      +Q + L +A+
Sbjct: 1585 QAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAE 1629



 Score = 37.4 bits (85), Expect = 0.056
 Identities = 137/772 (17%), Positives = 288/772 (37%), Gaps = 105/772 (13%)

Query: 68   EEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLL------DKAAQRDNEEETTDDPR 121
            EE+L  L K   ++      ++  T  Q  +  E +L      +KAA    E E      
Sbjct: 1860 EERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELE------ 1913

Query: 122  KLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARR 181
             L+ G I  N E      +  +++      L+    R      ++ ++    ++    +R
Sbjct: 1914 -LELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQR 1972

Query: 182  LAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFR- 240
             AAL++   L+A   E ++ R+R            E++ A       E   + L A+ + 
Sbjct: 1973 KAALEEVERLKAKVEEARRLRERA-----------EQESARQLQLAQEAAQKRLQAEEKA 2021

Query: 241  -----KLRQQDLDGELRSEKEGRDRKKDKQHLKRKKESDLPSAILQTSGVSEFTKKRSKL 295
                 + ++Q+L   L+ E+   D+ + +    R+   +   A +Q    +  ++++ + 
Sbjct: 2022 HAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEE 2081

Query: 296  VLPAPQISDAELQEVVKVGQASEIARQTAEESGITNS-ASSTLLSEYNVTNNSVALRTPR 354
                 Q ++ + Q   +   A+E  R+ AE+     + A    L +    +   A     
Sbjct: 2082 AERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAAD---AEMEKH 2138

Query: 355  TPASQDRILQEAQNLMALTNVDTPL------KGGLNTPLHESDFSGVTPQRQVVQTPNTV 408
               ++  + Q+AQ    LT +   L      K  L+  L           RQ  Q    +
Sbjct: 2139 KKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEEL 2198

Query: 409  LSTPFRTPSNGAEGLTPRSGTTPKPVINSTPGRTPLRDKLNINPEDGMADYSDPSYVKQM 468
             S   R        L  R     + +I        LRDK N                ++M
Sbjct: 2199 FSV--RVQMEELSKLKARIEAENRALI--------LRDKDN-------TQRFLQEEAEKM 2241

Query: 469  ERESREHLRLGLLGLPAPKNDFEIVLPENAEKEL-EEREIDDTYIEDAADVDARKQAIRD 527
            ++ + E  RL +    A +      L + AE++L ++R + +  +++      + QA+++
Sbjct: 2242 KQVAEEAARLSVAAQEAAR------LRQLAEEDLAQQRALAEKMLKE------KMQAVQE 2289

Query: 528  AERVKE----MKRMHKAVQKDLPRPSEVNETILRPLNVEPP------------LTDLQKS 571
            A R+K     +++  +  Q+   R  E  E + + L  E                ++   
Sbjct: 2290 ATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAE 2349

Query: 572  EELIKKEMITMLHYDLLHHPYEPSGNKKGKTVGFGTNNSEHITYLE---------HNPYE 622
             E +K  +  M               K+ + +G   + +E  T  +              
Sbjct: 2350 AERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQS 2409

Query: 623  KFSKEELKKAQDVLVQEMEVVKQGMSHGELSSEAYNQVWEECYSQVLYLPGQSRYTRANL 682
                E L++A   L +E E ++Q     +L SE    V +E   Q      QS  +  + 
Sbjct: 2410 DHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDS 2469

Query: 683  ASKKDR-IESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQL----ND 737
              +++R IE  + +LE        +A++  + +++ +  +   + R +  M++     ++
Sbjct: 2470 LLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHE 2529

Query: 738  LWDQIEQAHLELRTFEELKKHEDSAIPRRLECLKEDVQRQQEREKELQHRYA 789
              + + +   EL+  E+ ++ ++  +    + L+E +Q  +E     QHR A
Sbjct: 2530 AEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEE-----QHRAA 2576



 Score = 34.3 bits (77), Expect = 0.47
 Identities = 43/188 (22%), Positives = 87/188 (46%), Gaps = 16/188 (8%)

Query: 148  ELEMLSEARARLANTQGKKAKRKAR-----EKQLEEARRLAALQKRRELRAAGIEIQKKR 202
            E E   E   R A  +GK  ++  R     E++LE+ R+LA    ++ L A    I+ + 
Sbjct: 1629 EAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRA 1688

Query: 203  KRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKLRQQD---LDGELRSEKEGRD 259
            + ++G      +  E          + +  Q L+A+  K+R +    L  + R+E+E R 
Sbjct: 1689 ETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRS 1748

Query: 260  -RKKDKQHLKRK--KESDLPSAILQTSGVSEFTKKRSKLVL--PAPQISDAE---LQEVV 311
              +K KQ L+ +  +  +L     +   ++E  K++ +L     A Q ++AE    +++ 
Sbjct: 1749 TSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLA 1808

Query: 312  KVGQASEI 319
             +G+A+ +
Sbjct: 1809 AIGEATRL 1816


>gi|41322916 plectin 1 isoform 6 [Homo sapiens]
          Length = 4684

 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 60/285 (21%), Positives = 110/285 (38%), Gaps = 27/285 (9%)

Query: 91   RTAAQCLEHYEFLLDKAAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELE 150
            R   + +   E  +D   Q+ + +E     R+    EI        A        E+E+ 
Sbjct: 1533 RMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIR 1592

Query: 151  M----LSEARARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKR 206
            +    L     +    +G+    +AR ++ E  +R A  Q+  E     ++ + +RKR+ 
Sbjct: 1593 VVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQA--QEEAERLRRQVQDESQRKRQA 1650

Query: 207  GVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKLRQQDLDGELRSEKEGRDRKKDKQH 266
             V+  + +  E + A        E  +AL A         L+ ELR + E  +R+  +  
Sbjct: 1651 EVELASRVKAEAEAA-------REKQRALQA---------LE-ELRLQAEEAERRLRQAE 1693

Query: 267  LKRKKESDLPSAILQTSGVSEFTKKRSKLVLPAPQISDAELQEVVKVGQ----ASEIARQ 322
            ++R ++  +     Q S  +E   KR+       Q+  +  +E V V Q    A   A+Q
Sbjct: 1694 VERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQ 1753

Query: 323  TAEESGITNSASSTLLSEYNVTNNSVALRTPRTPASQDRILQEAQ 367
             AE       A   L       N ++ LR      +Q + L +A+
Sbjct: 1754 QAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAE 1798



 Score = 37.4 bits (85), Expect = 0.056
 Identities = 137/772 (17%), Positives = 288/772 (37%), Gaps = 105/772 (13%)

Query: 68   EEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLL------DKAAQRDNEEETTDDPR 121
            EE+L  L K   ++      ++  T  Q  +  E +L      +KAA    E E      
Sbjct: 2029 EERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELE------ 2082

Query: 122  KLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARR 181
             L+ G I  N E      +  +++      L+    R      ++ ++    ++    +R
Sbjct: 2083 -LELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQR 2141

Query: 182  LAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFR- 240
             AAL++   L+A   E ++ R+R            E++ A       E   + L A+ + 
Sbjct: 2142 KAALEEVERLKAKVEEARRLRERA-----------EQESARQLQLAQEAAQKRLQAEEKA 2190

Query: 241  -----KLRQQDLDGELRSEKEGRDRKKDKQHLKRKKESDLPSAILQTSGVSEFTKKRSKL 295
                 + ++Q+L   L+ E+   D+ + +    R+   +   A +Q    +  ++++ + 
Sbjct: 2191 HAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEE 2250

Query: 296  VLPAPQISDAELQEVVKVGQASEIARQTAEESGITNS-ASSTLLSEYNVTNNSVALRTPR 354
                 Q ++ + Q   +   A+E  R+ AE+     + A    L +    +   A     
Sbjct: 2251 AERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAAD---AEMEKH 2307

Query: 355  TPASQDRILQEAQNLMALTNVDTPL------KGGLNTPLHESDFSGVTPQRQVVQTPNTV 408
               ++  + Q+AQ    LT +   L      K  L+  L           RQ  Q    +
Sbjct: 2308 KKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEEL 2367

Query: 409  LSTPFRTPSNGAEGLTPRSGTTPKPVINSTPGRTPLRDKLNINPEDGMADYSDPSYVKQM 468
             S   R        L  R     + +I        LRDK N                ++M
Sbjct: 2368 FSV--RVQMEELSKLKARIEAENRALI--------LRDKDN-------TQRFLQEEAEKM 2410

Query: 469  ERESREHLRLGLLGLPAPKNDFEIVLPENAEKEL-EEREIDDTYIEDAADVDARKQAIRD 527
            ++ + E  RL +    A +      L + AE++L ++R + +  +++      + QA+++
Sbjct: 2411 KQVAEEAARLSVAAQEAAR------LRQLAEEDLAQQRALAEKMLKE------KMQAVQE 2458

Query: 528  AERVKE----MKRMHKAVQKDLPRPSEVNETILRPLNVEPP------------LTDLQKS 571
            A R+K     +++  +  Q+   R  E  E + + L  E                ++   
Sbjct: 2459 ATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAE 2518

Query: 572  EELIKKEMITMLHYDLLHHPYEPSGNKKGKTVGFGTNNSEHITYLE---------HNPYE 622
             E +K  +  M               K+ + +G   + +E  T  +              
Sbjct: 2519 AERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQS 2578

Query: 623  KFSKEELKKAQDVLVQEMEVVKQGMSHGELSSEAYNQVWEECYSQVLYLPGQSRYTRANL 682
                E L++A   L +E E ++Q     +L SE    V +E   Q      QS  +  + 
Sbjct: 2579 DHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDS 2638

Query: 683  ASKKDR-IESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQL----ND 737
              +++R IE  + +LE        +A++  + +++ +  +   + R +  M++     ++
Sbjct: 2639 LLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHE 2698

Query: 738  LWDQIEQAHLELRTFEELKKHEDSAIPRRLECLKEDVQRQQEREKELQHRYA 789
              + + +   EL+  E+ ++ ++  +    + L+E +Q  +E     QHR A
Sbjct: 2699 AEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEE-----QHRAA 2745



 Score = 34.3 bits (77), Expect = 0.47
 Identities = 43/188 (22%), Positives = 87/188 (46%), Gaps = 16/188 (8%)

Query: 148  ELEMLSEARARLANTQGKKAKRKAR-----EKQLEEARRLAALQKRRELRAAGIEIQKKR 202
            E E   E   R A  +GK  ++  R     E++LE+ R+LA    ++ L A    I+ + 
Sbjct: 1798 EAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRA 1857

Query: 203  KRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKLRQQD---LDGELRSEKEGRD 259
            + ++G      +  E          + +  Q L+A+  K+R +    L  + R+E+E R 
Sbjct: 1858 ETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRS 1917

Query: 260  -RKKDKQHLKRK--KESDLPSAILQTSGVSEFTKKRSKLVL--PAPQISDAE---LQEVV 311
              +K KQ L+ +  +  +L     +   ++E  K++ +L     A Q ++AE    +++ 
Sbjct: 1918 TSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLA 1977

Query: 312  KVGQASEI 319
             +G+A+ +
Sbjct: 1978 AIGEATRL 1985


>gi|41322908 plectin 1 isoform 3 [Homo sapiens]
          Length = 4525

 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 60/285 (21%), Positives = 110/285 (38%), Gaps = 27/285 (9%)

Query: 91   RTAAQCLEHYEFLLDKAAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELE 150
            R   + +   E  +D   Q+ + +E     R+    EI        A        E+E+ 
Sbjct: 1374 RMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIR 1433

Query: 151  M----LSEARARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKR 206
            +    L     +    +G+    +AR ++ E  +R A  Q+  E     ++ + +RKR+ 
Sbjct: 1434 VVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQA--QEEAERLRRQVQDESQRKRQA 1491

Query: 207  GVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKLRQQDLDGELRSEKEGRDRKKDKQH 266
             V+  + +  E + A        E  +AL A         L+ ELR + E  +R+  +  
Sbjct: 1492 EVELASRVKAEAEAA-------REKQRALQA---------LE-ELRLQAEEAERRLRQAE 1534

Query: 267  LKRKKESDLPSAILQTSGVSEFTKKRSKLVLPAPQISDAELQEVVKVGQ----ASEIARQ 322
            ++R ++  +     Q S  +E   KR+       Q+  +  +E V V Q    A   A+Q
Sbjct: 1535 VERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQ 1594

Query: 323  TAEESGITNSASSTLLSEYNVTNNSVALRTPRTPASQDRILQEAQ 367
             AE       A   L       N ++ LR      +Q + L +A+
Sbjct: 1595 QAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAE 1639



 Score = 37.4 bits (85), Expect = 0.056
 Identities = 137/772 (17%), Positives = 288/772 (37%), Gaps = 105/772 (13%)

Query: 68   EEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLL------DKAAQRDNEEETTDDPR 121
            EE+L  L K   ++      ++  T  Q  +  E +L      +KAA    E E      
Sbjct: 1870 EERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELE------ 1923

Query: 122  KLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARR 181
             L+ G I  N E      +  +++      L+    R      ++ ++    ++    +R
Sbjct: 1924 -LELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQR 1982

Query: 182  LAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFR- 240
             AAL++   L+A   E ++ R+R            E++ A       E   + L A+ + 
Sbjct: 1983 KAALEEVERLKAKVEEARRLRERA-----------EQESARQLQLAQEAAQKRLQAEEKA 2031

Query: 241  -----KLRQQDLDGELRSEKEGRDRKKDKQHLKRKKESDLPSAILQTSGVSEFTKKRSKL 295
                 + ++Q+L   L+ E+   D+ + +    R+   +   A +Q    +  ++++ + 
Sbjct: 2032 HAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEE 2091

Query: 296  VLPAPQISDAELQEVVKVGQASEIARQTAEESGITNS-ASSTLLSEYNVTNNSVALRTPR 354
                 Q ++ + Q   +   A+E  R+ AE+     + A    L +    +   A     
Sbjct: 2092 AERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAAD---AEMEKH 2148

Query: 355  TPASQDRILQEAQNLMALTNVDTPL------KGGLNTPLHESDFSGVTPQRQVVQTPNTV 408
               ++  + Q+AQ    LT +   L      K  L+  L           RQ  Q    +
Sbjct: 2149 KKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEEL 2208

Query: 409  LSTPFRTPSNGAEGLTPRSGTTPKPVINSTPGRTPLRDKLNINPEDGMADYSDPSYVKQM 468
             S   R        L  R     + +I        LRDK N                ++M
Sbjct: 2209 FSV--RVQMEELSKLKARIEAENRALI--------LRDKDN-------TQRFLQEEAEKM 2251

Query: 469  ERESREHLRLGLLGLPAPKNDFEIVLPENAEKEL-EEREIDDTYIEDAADVDARKQAIRD 527
            ++ + E  RL +    A +      L + AE++L ++R + +  +++      + QA+++
Sbjct: 2252 KQVAEEAARLSVAAQEAAR------LRQLAEEDLAQQRALAEKMLKE------KMQAVQE 2299

Query: 528  AERVKE----MKRMHKAVQKDLPRPSEVNETILRPLNVEPP------------LTDLQKS 571
            A R+K     +++  +  Q+   R  E  E + + L  E                ++   
Sbjct: 2300 ATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAE 2359

Query: 572  EELIKKEMITMLHYDLLHHPYEPSGNKKGKTVGFGTNNSEHITYLE---------HNPYE 622
             E +K  +  M               K+ + +G   + +E  T  +              
Sbjct: 2360 AERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQS 2419

Query: 623  KFSKEELKKAQDVLVQEMEVVKQGMSHGELSSEAYNQVWEECYSQVLYLPGQSRYTRANL 682
                E L++A   L +E E ++Q     +L SE    V +E   Q      QS  +  + 
Sbjct: 2420 DHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDS 2479

Query: 683  ASKKDR-IESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQL----ND 737
              +++R IE  + +LE        +A++  + +++ +  +   + R +  M++     ++
Sbjct: 2480 LLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHE 2539

Query: 738  LWDQIEQAHLELRTFEELKKHEDSAIPRRLECLKEDVQRQQEREKELQHRYA 789
              + + +   EL+  E+ ++ ++  +    + L+E +Q  +E     QHR A
Sbjct: 2540 AEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEE-----QHRAA 2586



 Score = 34.3 bits (77), Expect = 0.47
 Identities = 43/188 (22%), Positives = 87/188 (46%), Gaps = 16/188 (8%)

Query: 148  ELEMLSEARARLANTQGKKAKRKAR-----EKQLEEARRLAALQKRRELRAAGIEIQKKR 202
            E E   E   R A  +GK  ++  R     E++LE+ R+LA    ++ L A    I+ + 
Sbjct: 1639 EAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRA 1698

Query: 203  KRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKLRQQD---LDGELRSEKEGRD 259
            + ++G      +  E          + +  Q L+A+  K+R +    L  + R+E+E R 
Sbjct: 1699 ETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRS 1758

Query: 260  -RKKDKQHLKRK--KESDLPSAILQTSGVSEFTKKRSKLVL--PAPQISDAE---LQEVV 311
              +K KQ L+ +  +  +L     +   ++E  K++ +L     A Q ++AE    +++ 
Sbjct: 1759 TSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLA 1818

Query: 312  KVGQASEI 319
             +G+A+ +
Sbjct: 1819 AIGEATRL 1826


>gi|41322912 plectin 1 isoform 2 [Homo sapiens]
          Length = 4533

 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 60/285 (21%), Positives = 110/285 (38%), Gaps = 27/285 (9%)

Query: 91   RTAAQCLEHYEFLLDKAAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELE 150
            R   + +   E  +D   Q+ + +E     R+    EI        A        E+E+ 
Sbjct: 1382 RMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIR 1441

Query: 151  M----LSEARARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKR 206
            +    L     +    +G+    +AR ++ E  +R A  Q+  E     ++ + +RKR+ 
Sbjct: 1442 VVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQA--QEEAERLRRQVQDESQRKRQA 1499

Query: 207  GVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKLRQQDLDGELRSEKEGRDRKKDKQH 266
             V+  + +  E + A        E  +AL A         L+ ELR + E  +R+  +  
Sbjct: 1500 EVELASRVKAEAEAA-------REKQRALQA---------LE-ELRLQAEEAERRLRQAE 1542

Query: 267  LKRKKESDLPSAILQTSGVSEFTKKRSKLVLPAPQISDAELQEVVKVGQ----ASEIARQ 322
            ++R ++  +     Q S  +E   KR+       Q+  +  +E V V Q    A   A+Q
Sbjct: 1543 VERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQ 1602

Query: 323  TAEESGITNSASSTLLSEYNVTNNSVALRTPRTPASQDRILQEAQ 367
             AE       A   L       N ++ LR      +Q + L +A+
Sbjct: 1603 QAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAE 1647



 Score = 37.4 bits (85), Expect = 0.056
 Identities = 137/772 (17%), Positives = 288/772 (37%), Gaps = 105/772 (13%)

Query: 68   EEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLL------DKAAQRDNEEETTDDPR 121
            EE+L  L K   ++      ++  T  Q  +  E +L      +KAA    E E      
Sbjct: 1878 EERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELE------ 1931

Query: 122  KLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARR 181
             L+ G I  N E      +  +++      L+    R      ++ ++    ++    +R
Sbjct: 1932 -LELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQR 1990

Query: 182  LAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFR- 240
             AAL++   L+A   E ++ R+R            E++ A       E   + L A+ + 
Sbjct: 1991 KAALEEVERLKAKVEEARRLRERA-----------EQESARQLQLAQEAAQKRLQAEEKA 2039

Query: 241  -----KLRQQDLDGELRSEKEGRDRKKDKQHLKRKKESDLPSAILQTSGVSEFTKKRSKL 295
                 + ++Q+L   L+ E+   D+ + +    R+   +   A +Q    +  ++++ + 
Sbjct: 2040 HAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEE 2099

Query: 296  VLPAPQISDAELQEVVKVGQASEIARQTAEESGITNS-ASSTLLSEYNVTNNSVALRTPR 354
                 Q ++ + Q   +   A+E  R+ AE+     + A    L +    +   A     
Sbjct: 2100 AERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAAD---AEMEKH 2156

Query: 355  TPASQDRILQEAQNLMALTNVDTPL------KGGLNTPLHESDFSGVTPQRQVVQTPNTV 408
               ++  + Q+AQ    LT +   L      K  L+  L           RQ  Q    +
Sbjct: 2157 KKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEEL 2216

Query: 409  LSTPFRTPSNGAEGLTPRSGTTPKPVINSTPGRTPLRDKLNINPEDGMADYSDPSYVKQM 468
             S   R        L  R     + +I        LRDK N                ++M
Sbjct: 2217 FSV--RVQMEELSKLKARIEAENRALI--------LRDKDN-------TQRFLQEEAEKM 2259

Query: 469  ERESREHLRLGLLGLPAPKNDFEIVLPENAEKEL-EEREIDDTYIEDAADVDARKQAIRD 527
            ++ + E  RL +    A +      L + AE++L ++R + +  +++      + QA+++
Sbjct: 2260 KQVAEEAARLSVAAQEAAR------LRQLAEEDLAQQRALAEKMLKE------KMQAVQE 2307

Query: 528  AERVKE----MKRMHKAVQKDLPRPSEVNETILRPLNVEPP------------LTDLQKS 571
            A R+K     +++  +  Q+   R  E  E + + L  E                ++   
Sbjct: 2308 ATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAE 2367

Query: 572  EELIKKEMITMLHYDLLHHPYEPSGNKKGKTVGFGTNNSEHITYLE---------HNPYE 622
             E +K  +  M               K+ + +G   + +E  T  +              
Sbjct: 2368 AERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQS 2427

Query: 623  KFSKEELKKAQDVLVQEMEVVKQGMSHGELSSEAYNQVWEECYSQVLYLPGQSRYTRANL 682
                E L++A   L +E E ++Q     +L SE    V +E   Q      QS  +  + 
Sbjct: 2428 DHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDS 2487

Query: 683  ASKKDR-IESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQL----ND 737
              +++R IE  + +LE        +A++  + +++ +  +   + R +  M++     ++
Sbjct: 2488 LLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHE 2547

Query: 738  LWDQIEQAHLELRTFEELKKHEDSAIPRRLECLKEDVQRQQEREKELQHRYA 789
              + + +   EL+  E+ ++ ++  +    + L+E +Q  +E     QHR A
Sbjct: 2548 AEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEE-----QHRAA 2594



 Score = 34.3 bits (77), Expect = 0.47
 Identities = 43/188 (22%), Positives = 87/188 (46%), Gaps = 16/188 (8%)

Query: 148  ELEMLSEARARLANTQGKKAKRKAR-----EKQLEEARRLAALQKRRELRAAGIEIQKKR 202
            E E   E   R A  +GK  ++  R     E++LE+ R+LA    ++ L A    I+ + 
Sbjct: 1647 EAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRA 1706

Query: 203  KRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKLRQQD---LDGELRSEKEGRD 259
            + ++G      +  E          + +  Q L+A+  K+R +    L  + R+E+E R 
Sbjct: 1707 ETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRS 1766

Query: 260  -RKKDKQHLKRK--KESDLPSAILQTSGVSEFTKKRSKLVL--PAPQISDAE---LQEVV 311
              +K KQ L+ +  +  +L     +   ++E  K++ +L     A Q ++AE    +++ 
Sbjct: 1767 TSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLA 1826

Query: 312  KVGQASEI 319
             +G+A+ +
Sbjct: 1827 AIGEATRL 1834


>gi|47607492 plectin 1 isoform 1 [Homo sapiens]
          Length = 4574

 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 60/285 (21%), Positives = 110/285 (38%), Gaps = 27/285 (9%)

Query: 91   RTAAQCLEHYEFLLDKAAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELE 150
            R   + +   E  +D   Q+ + +E     R+    EI        A        E+E+ 
Sbjct: 1423 RMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIR 1482

Query: 151  M----LSEARARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKR 206
            +    L     +    +G+    +AR ++ E  +R A  Q+  E     ++ + +RKR+ 
Sbjct: 1483 VVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQA--QEEAERLRRQVQDESQRKRQA 1540

Query: 207  GVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKLRQQDLDGELRSEKEGRDRKKDKQH 266
             V+  + +  E + A        E  +AL A         L+ ELR + E  +R+  +  
Sbjct: 1541 EVELASRVKAEAEAA-------REKQRALQA---------LE-ELRLQAEEAERRLRQAE 1583

Query: 267  LKRKKESDLPSAILQTSGVSEFTKKRSKLVLPAPQISDAELQEVVKVGQ----ASEIARQ 322
            ++R ++  +     Q S  +E   KR+       Q+  +  +E V V Q    A   A+Q
Sbjct: 1584 VERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQ 1643

Query: 323  TAEESGITNSASSTLLSEYNVTNNSVALRTPRTPASQDRILQEAQ 367
             AE       A   L       N ++ LR      +Q + L +A+
Sbjct: 1644 QAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAE 1688



 Score = 37.4 bits (85), Expect = 0.056
 Identities = 137/772 (17%), Positives = 288/772 (37%), Gaps = 105/772 (13%)

Query: 68   EEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLL------DKAAQRDNEEETTDDPR 121
            EE+L  L K   ++      ++  T  Q  +  E +L      +KAA    E E      
Sbjct: 1919 EERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELE------ 1972

Query: 122  KLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARR 181
             L+ G I  N E      +  +++      L+    R      ++ ++    ++    +R
Sbjct: 1973 -LELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQR 2031

Query: 182  LAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFR- 240
             AAL++   L+A   E ++ R+R            E++ A       E   + L A+ + 
Sbjct: 2032 KAALEEVERLKAKVEEARRLRERA-----------EQESARQLQLAQEAAQKRLQAEEKA 2080

Query: 241  -----KLRQQDLDGELRSEKEGRDRKKDKQHLKRKKESDLPSAILQTSGVSEFTKKRSKL 295
                 + ++Q+L   L+ E+   D+ + +    R+   +   A +Q    +  ++++ + 
Sbjct: 2081 HAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEE 2140

Query: 296  VLPAPQISDAELQEVVKVGQASEIARQTAEESGITNS-ASSTLLSEYNVTNNSVALRTPR 354
                 Q ++ + Q   +   A+E  R+ AE+     + A    L +    +   A     
Sbjct: 2141 AERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAAD---AEMEKH 2197

Query: 355  TPASQDRILQEAQNLMALTNVDTPL------KGGLNTPLHESDFSGVTPQRQVVQTPNTV 408
               ++  + Q+AQ    LT +   L      K  L+  L           RQ  Q    +
Sbjct: 2198 KKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEEL 2257

Query: 409  LSTPFRTPSNGAEGLTPRSGTTPKPVINSTPGRTPLRDKLNINPEDGMADYSDPSYVKQM 468
             S   R        L  R     + +I        LRDK N                ++M
Sbjct: 2258 FSV--RVQMEELSKLKARIEAENRALI--------LRDKDN-------TQRFLQEEAEKM 2300

Query: 469  ERESREHLRLGLLGLPAPKNDFEIVLPENAEKEL-EEREIDDTYIEDAADVDARKQAIRD 527
            ++ + E  RL +    A +      L + AE++L ++R + +  +++      + QA+++
Sbjct: 2301 KQVAEEAARLSVAAQEAAR------LRQLAEEDLAQQRALAEKMLKE------KMQAVQE 2348

Query: 528  AERVKE----MKRMHKAVQKDLPRPSEVNETILRPLNVEPP------------LTDLQKS 571
            A R+K     +++  +  Q+   R  E  E + + L  E                ++   
Sbjct: 2349 ATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAE 2408

Query: 572  EELIKKEMITMLHYDLLHHPYEPSGNKKGKTVGFGTNNSEHITYLE---------HNPYE 622
             E +K  +  M               K+ + +G   + +E  T  +              
Sbjct: 2409 AERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQS 2468

Query: 623  KFSKEELKKAQDVLVQEMEVVKQGMSHGELSSEAYNQVWEECYSQVLYLPGQSRYTRANL 682
                E L++A   L +E E ++Q     +L SE    V +E   Q      QS  +  + 
Sbjct: 2469 DHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDS 2528

Query: 683  ASKKDR-IESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQL----ND 737
              +++R IE  + +LE        +A++  + +++ +  +   + R +  M++     ++
Sbjct: 2529 LLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHE 2588

Query: 738  LWDQIEQAHLELRTFEELKKHEDSAIPRRLECLKEDVQRQQEREKELQHRYA 789
              + + +   EL+  E+ ++ ++  +    + L+E +Q  +E     QHR A
Sbjct: 2589 AEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEE-----QHRAA 2635



 Score = 34.3 bits (77), Expect = 0.47
 Identities = 43/188 (22%), Positives = 87/188 (46%), Gaps = 16/188 (8%)

Query: 148  ELEMLSEARARLANTQGKKAKRKAR-----EKQLEEARRLAALQKRRELRAAGIEIQKKR 202
            E E   E   R A  +GK  ++  R     E++LE+ R+LA    ++ L A    I+ + 
Sbjct: 1688 EAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRA 1747

Query: 203  KRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKLRQQD---LDGELRSEKEGRD 259
            + ++G      +  E          + +  Q L+A+  K+R +    L  + R+E+E R 
Sbjct: 1748 ETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRS 1807

Query: 260  -RKKDKQHLKRK--KESDLPSAILQTSGVSEFTKKRSKLVL--PAPQISDAE---LQEVV 311
              +K KQ L+ +  +  +L     +   ++E  K++ +L     A Q ++AE    +++ 
Sbjct: 1808 TSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLA 1867

Query: 312  KVGQASEI 319
             +G+A+ +
Sbjct: 1868 AIGEATRL 1875


>gi|22538461 nuclear receptor co-repressor 1 [Homo sapiens]
          Length = 2440

 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 56/249 (22%), Positives = 91/249 (36%), Gaps = 28/249 (11%)

Query: 11  WRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEK 70
           W   E E+ K  ++++G+N W+ IA ++  KS  QCK  ++ +           R   + 
Sbjct: 628 WTEEEMEVAKKGLVEHGRN-WAAIAKMVGTKSEAQCKNFYFNYK---------RRHNLDN 677

Query: 71  LLHLAKLMPTQWRTIAPIIGRTAAQC---LEHYEFLLDKAAQRDNEEETTDDP--RKLKP 125
           LL   K    Q  +  P   R  +QC           D+  +  NEEE  +D     +KP
Sbjct: 678 LLQQHK----QKTSRKPREERDVSQCESVASTVSAQEDEDIEASNEEENPEDSEVEAVKP 733

Query: 126 GEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQL------EEA 179
            E  P   T     +P    E   E        LA    K A+ ++ E Q+      E A
Sbjct: 734 SEDSPENATSRGNTEPAVELEPTTETAPSTSPSLAVPSTKPAEDESVETQVNDSISAETA 793

Query: 180 RRLAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADF 239
            ++   Q+        +       +   VD    +P      +   +T E +   LD   
Sbjct: 794 EQMDVDQQEHSAEEGSVCDPPPATKADSVDVEVRVPENHASKVEGDNTKERD---LDRAS 850

Query: 240 RKLRQQDLD 248
            K+  +D D
Sbjct: 851 EKVEPRDED 859



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 84/375 (22%), Positives = 138/375 (36%), Gaps = 44/375 (11%)

Query: 10  VWRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEE 69
           VW + E EI K   +++ KN +  IAS L RKS   C   +Y             + E  
Sbjct: 439 VWTDHEKEIFKDKFIQHPKN-FGLIASYLERKSVPDCVLYYYLT----------KKNENY 487

Query: 70  KLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLLDKAAQRDNEEETTDDPRKLKPGEID 129
           K L        + R    I   +  + +E  E   DKA + + +EE   D  + K  + D
Sbjct: 488 KALVRRNYGKRRGRN-QQIARPSQEEKVEEKEE--DKAEKTEKKEEEKKDEEE-KDEKED 543

Query: 130 PNPETKPARPDPIDMDEDELEMLSEARAR---LANTQGKKAKRKAREKQLEEARRLAALQ 186
               TK    D ID   +E E   +A  R    AN+QG++  R  R    E A   AA  
Sbjct: 544 SKENTK--EKDKIDGTAEETEEREQATPRGRKTANSQGRRKGRITRSMTNEAAAASAAAA 601

Query: 187 KRRE------------LRAAGIEIQKKRKRKRGVDYNAEIPFEKK-PALGFYDTSEENYQ 233
              E            +    +E  +  + +  V     +   +   A+     ++   Q
Sbjct: 602 AATEEPPPPLPPPPEPISTEPVETSRWTEEEMEVAKKGLVEHGRNWAAIAKMVGTKSEAQ 661

Query: 234 ALDADFRKLRQQDLDGELRSEKEGRDRKKDKQHLKRKKESDLPSAILQTSGVSEFTKKRS 293
             +  F   R+ +LD  L+  K+   RK        ++E D+       S VS    +  
Sbjct: 662 CKNFYFNYKRRHNLDNLLQQHKQKTSRKP-------REERDVSQCESVASTVSAQEDEDI 714

Query: 294 KLVLPAPQISDAELQEVVKVGQASEIARQTAEESGITNSASSTLLSEYNVTNNSVALRTP 353
           +         D+E++ V    + SE + + A   G T  A     +     + S +L  P
Sbjct: 715 EASNEEENPEDSEVEAV----KPSEDSPENATSRGNTEPAVELEPTTETAPSTSPSLAVP 770

Query: 354 RTPASQDRILQEAQN 368
            T  ++D  ++   N
Sbjct: 771 STKPAEDESVETQVN 785


>gi|169167715 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 285

 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 35/131 (26%), Positives = 62/131 (47%), Gaps = 4/131 (3%)

Query: 142 IDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKK 201
           I+ D D        R R  +   K+ +   R+++ E  R+    ++R   R    E  ++
Sbjct: 84  IEKDRDRQRKRDRERQRWRDRDRKRERWGDRDRETETERQEERERQRDRKREKDRE--RQ 141

Query: 202 RKRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKLRQ--QDLDGELRSEKEGRD 259
           R+R+ G+D + EI  EK           E Y+  + + +K R+  +D D E + EKE R+
Sbjct: 142 RQREIGIDKDREIETEKDRDREREMGETERYRDRERERQKQRETRRDRDRERQREKEDRE 201

Query: 260 RKKDKQHLKRK 270
           R +D+Q  + K
Sbjct: 202 RDRDRQKEREK 212



 Score = 39.3 bits (90), Expect = 0.015
 Identities = 43/186 (23%), Positives = 74/186 (39%), Gaps = 21/186 (11%)

Query: 105 DKAAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQG 164
           D+  +RD E +   D  + +    D + ET+  R +  +   D        R R      
Sbjct: 89  DRQRKRDRERQRWRDRDRKRERWGDRDRETETERQEERERQRDRKREKDRERQRQREIGI 148

Query: 165 KKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGF 224
            K +    EK  +  R +   ++ R+      E QK+R+ +R  D   +           
Sbjct: 149 DKDREIETEKDRDREREMGETERYRDRER---ERQKQRETRRDRDRERQ----------- 194

Query: 225 YDTSEENYQALDADFRKLRQQDLDGELRSEKEGRDRKKDK-QHLKRKKESDLPSAILQTS 283
               E+  +  D D +K R++D     R  + GRDR K++ +  +R+K+ D   AI    
Sbjct: 195 ---REKEDRERDRDRQKEREKD---RYRERETGRDRDKERDRERQREKDRDRQKAIDCVP 248

Query: 284 GVSEFT 289
           G  E T
Sbjct: 249 GRWEVT 254



 Score = 30.4 bits (67), Expect = 6.8
 Identities = 28/106 (26%), Positives = 45/106 (42%), Gaps = 27/106 (25%)

Query: 170 KAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFYDTSE 229
           + RE+Q E  R+    ++R   +   IE  + R+RKR                       
Sbjct: 58  RERERQRERERQRKRAKERHREKDREIEKDRDRQRKR---------------------DR 96

Query: 230 ENYQALDADFRKLRQQDLDGELRSEK-EGRDRKKDKQHLKRKKESD 274
           E  +  D D ++ R  D D E  +E+ E R+R++D     RK+E D
Sbjct: 97  ERQRWRDRDRKRERWGDRDRETETERQEERERQRD-----RKREKD 137


>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 275

 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 36/164 (21%), Positives = 72/164 (43%), Gaps = 2/164 (1%)

Query: 109 QRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAK 168
           +R+  +   +  RK + G+ +     K  R    +    E E   + R      + KK K
Sbjct: 42  EREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEK 101

Query: 169 RKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFYDTS 228
           +K   KQ    RR    +K R+ R    + +++RKRK+          +++   G  +  
Sbjct: 102 KKRERKQ--RGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERK 159

Query: 229 EENYQALDADFRKLRQQDLDGELRSEKEGRDRKKDKQHLKRKKE 272
            +  +  + + ++ R +    + R  KE R+RKK+++  +RKK+
Sbjct: 160 RKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKK 203



 Score = 38.5 bits (88), Expect = 0.025
 Identities = 32/124 (25%), Positives = 57/124 (45%), Gaps = 15/124 (12%)

Query: 165 KKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGF 224
           +K KRK RE+  E  R+    +K+R+ R    E +K++K K+  +       E+K     
Sbjct: 62  EKKKRKKRERGKERERKRKEREKQRKERREK-ERRKRKKEKKKRERKQRGRRERKKKKER 120

Query: 225 YDTSEENYQALDADFRKLRQQDLDGELRSEKEG--------------RDRKKDKQHLKRK 270
            +   EN Q  +   +K R++    E + EKE               R++K+++   +RK
Sbjct: 121 KERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERK 180

Query: 271 KESD 274
           KE +
Sbjct: 181 KERE 184



 Score = 38.1 bits (87), Expect = 0.033
 Identities = 34/129 (26%), Positives = 59/129 (45%), Gaps = 8/129 (6%)

Query: 154 EARARLANTQGKKA--KRKAREKQLEEAR------RLAALQKRRELRAAGIEIQKKRKRK 205
           E + R    +GK+   KRK REKQ +E R      R    +KR   +    E +KK++RK
Sbjct: 62  EKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERK 121

Query: 206 RGVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKLRQQDLDGELRSEKEGRDRKKDKQ 265
                N +    K+         +E  +  +   R+ +++    E R +K  R+RK+ K+
Sbjct: 122 ERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKK 181

Query: 266 HLKRKKESD 274
             +RK+  +
Sbjct: 182 ERERKERRE 190



 Score = 36.6 bits (83), Expect = 0.095
 Identities = 31/126 (24%), Positives = 63/126 (50%), Gaps = 14/126 (11%)

Query: 148 ELEMLSEARARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKRG 207
           EL+M+S +      TQ +  ++K R    E  +R    +K R+      E +K++KR+RG
Sbjct: 16  ELQMVSCSHISKPCTQRESERKKERR---EREKRKREREKERKRERGKKEKKKRKKRERG 72

Query: 208 VDYNAEIPFEKKPALGFYDTSEENYQALDADFRKLRQQDLDGELRSEKEGRDRKKDKQHL 267
            +       E+K      +  ++  +  + + RK +++    E R ++  R+RKK K+  
Sbjct: 73  KER------ERKRK----EREKQRKERREKERRKRKKEKKKRE-RKQRGRRERKKKKERK 121

Query: 268 KRKKES 273
           +R++E+
Sbjct: 122 EREREN 127



 Score = 33.5 bits (75), Expect = 0.80
 Identities = 35/142 (24%), Positives = 61/142 (42%), Gaps = 13/142 (9%)

Query: 141 PIDMDEDELEMLSEARARLANTQGKKAKRK----------AREKQLEEARRLAALQKRRE 190
           P    E E +     R +    + K+ KR+           RE+  E  R+    +K+R+
Sbjct: 28  PCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRK 87

Query: 191 LRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKLRQQDLDGE 250
            R    E +K++K K+  +       E+K      +   EN Q  +   +K R++    E
Sbjct: 88  ERREK-ERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKE 146

Query: 251 LRSEKEGRDRKKDKQHLKRKKE 272
            + EKE    K++++  KRKKE
Sbjct: 147 RKREKE--RGKRERKRKKRKKE 166



 Score = 30.8 bits (68), Expect = 5.2
 Identities = 34/161 (21%), Positives = 65/161 (40%), Gaps = 27/161 (16%)

Query: 106 KAAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGK 165
           K  ++  +E    + RK K  +     + +  R      +  E E  ++ R      + +
Sbjct: 80  KEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRR 139

Query: 166 KAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFY 225
           K KR+   K+ +E  +    +K+R+      E +KKR+R R                   
Sbjct: 140 KKKRRKERKREKERGKRERKRKKRKKE----EREKKRERNR------------------- 176

Query: 226 DTSEENYQALDADFRKLRQQDLDGELRSEKE-GRDRKKDKQ 265
              +E  +  +   R+ R+++   E R +KE  +DRK D+Q
Sbjct: 177 ---KERKKERERKERRERKKERKKERRKKKERKKDRKTDRQ 214


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.129    0.360 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 31,634,803
Number of Sequences: 37866
Number of extensions: 1571411
Number of successful extensions: 9167
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 70
Number of HSP's successfully gapped in prelim test: 559
Number of HSP's that attempted gapping in prelim test: 7120
Number of HSP's gapped (non-prelim): 2305
length of query: 802
length of database: 18,247,518
effective HSP length: 110
effective length of query: 692
effective length of database: 14,082,258
effective search space: 9744922536
effective search space used: 9744922536
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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