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Search of human proteins with 167466276
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|167466276 protein phosphatase 1K (PP2C domain containing)
[Homo sapiens]
(372 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|167466276 protein phosphatase 1K (PP2C domain containing) [Ho... 756 0.0
gi|63003905 protein phosphatase 1 (formerly 2C)-like [Homo sapiens] 130 2e-30
gi|13540531 integrin-linked kinase-associated protein phosphatas... 112 7e-25
gi|10337595 protein phosphatase 1A isoform 1 [Homo sapiens] 111 9e-25
gi|29557855 protein phosphatase 1A isoform 2 [Homo sapiens] 111 9e-25
gi|193211600 protein phosphatase 1A isoform 3 [Homo sapiens] 111 9e-25
gi|30089948 protein phosphatase 1E [Homo sapiens] 110 2e-24
gi|7661862 protein phosphatase 1F [Homo sapiens] 103 2e-22
gi|75813620 protein phosphatase 1B isoform 5 [Homo sapiens] 101 9e-22
gi|75813618 protein phosphatase 1B isoform 4 [Homo sapiens] 101 9e-22
gi|29558022 protein phosphatase 1B isoform 2 [Homo sapiens] 101 9e-22
gi|4505995 protein phosphatase 1B isoform 1 [Homo sapiens] 101 9e-22
gi|122937199 protein phosphatase 1B-like [Homo sapiens] 84 2e-16
gi|4505999 protein phosphatase 1G [Homo sapiens] 84 3e-16
gi|29826282 protein phosphatase 1G [Homo sapiens] 84 3e-16
gi|4505997 protein phosphatase 1D [Homo sapiens] 71 2e-12
gi|37221175 PH domain and leucine rich repeat protein phosphatas... 61 1e-09
gi|65301141 PH domain and leucine rich repeat protein phosphatas... 51 1e-06
gi|5174703 mitogen-activated protein kinase kinase kinase 7 inte... 49 7e-06
gi|41281798 mitogen-activated protein kinase kinase kinase 7 int... 49 7e-06
gi|45439339 pyruvate dehyrogenase phosphatase catalytic subunit ... 45 1e-04
gi|239985428 pyruvate dehyrogenase phosphatase catalytic subunit... 45 1e-04
gi|239985426 pyruvate dehyrogenase phosphatase catalytic subunit... 45 1e-04
gi|239985422 pyruvate dehyrogenase phosphatase catalytic subunit... 45 1e-04
gi|239985420 pyruvate dehyrogenase phosphatase catalytic subunit... 45 1e-04
gi|149944715 protein phosphatase 1H (PP2C domain containing) [Ho... 42 9e-04
gi|41349497 pyruvate dehydrogenase phosphatase isoenzyme 2 [Homo... 40 0.003
gi|171460932 protein phosphatase 1M isoform a [Homo sapiens] 39 0.006
gi|171460934 protein phosphatase 1M isoform b [Homo sapiens] 37 0.022
gi|65506328 protein phosphatase 1J (PP2C domain containing) [Hom... 37 0.029
>gi|167466276 protein phosphatase 1K (PP2C domain containing) [Homo
sapiens]
Length = 372
Score = 756 bits (1951), Expect = 0.0
Identities = 372/372 (100%), Positives = 372/372 (100%)
Query: 1 MSTAALITLVRSGGNQVRRRVLLSSRLLQDDRRVTPTCHSSTSEPRCSRFDPDGSGSPAT 60
MSTAALITLVRSGGNQVRRRVLLSSRLLQDDRRVTPTCHSSTSEPRCSRFDPDGSGSPAT
Sbjct: 1 MSTAALITLVRSGGNQVRRRVLLSSRLLQDDRRVTPTCHSSTSEPRCSRFDPDGSGSPAT 60
Query: 61 WDNFGIWDNRIDEPILLPPSIKYGKPIPKISLENVGCASQIGKRKENEDRFDFAQLTDEV 120
WDNFGIWDNRIDEPILLPPSIKYGKPIPKISLENVGCASQIGKRKENEDRFDFAQLTDEV
Sbjct: 61 WDNFGIWDNRIDEPILLPPSIKYGKPIPKISLENVGCASQIGKRKENEDRFDFAQLTDEV 120
Query: 121 LYFAVYDGHGGPAAADFCHTHMEKCIMDLLPKEKNLETLLTLAFLEIDKAFSSHARLSAD 180
LYFAVYDGHGGPAAADFCHTHMEKCIMDLLPKEKNLETLLTLAFLEIDKAFSSHARLSAD
Sbjct: 121 LYFAVYDGHGGPAAADFCHTHMEKCIMDLLPKEKNLETLLTLAFLEIDKAFSSHARLSAD 180
Query: 181 ATLLTSGTTATVALLRDGIELVVASVGDSRAILCRKGKPMKLTIDHTPERKDEKERIKKC 240
ATLLTSGTTATVALLRDGIELVVASVGDSRAILCRKGKPMKLTIDHTPERKDEKERIKKC
Sbjct: 181 ATLLTSGTTATVALLRDGIELVVASVGDSRAILCRKGKPMKLTIDHTPERKDEKERIKKC 240
Query: 241 GGFVAWNSLGQPHVNGRLAMTRSIGDLDLKTSGVIAEPETKRIKLHHADDSFLVLTTDGI 300
GGFVAWNSLGQPHVNGRLAMTRSIGDLDLKTSGVIAEPETKRIKLHHADDSFLVLTTDGI
Sbjct: 241 GGFVAWNSLGQPHVNGRLAMTRSIGDLDLKTSGVIAEPETKRIKLHHADDSFLVLTTDGI 300
Query: 301 NFMVNSQEICDFVNQCHDPNEAAHAVTEQAIQYGTEDNSTAVVVPFGAWGKYKNSEINFS 360
NFMVNSQEICDFVNQCHDPNEAAHAVTEQAIQYGTEDNSTAVVVPFGAWGKYKNSEINFS
Sbjct: 301 NFMVNSQEICDFVNQCHDPNEAAHAVTEQAIQYGTEDNSTAVVVPFGAWGKYKNSEINFS 360
Query: 361 FSRSFASSGRWA 372
FSRSFASSGRWA
Sbjct: 361 FSRSFASSGRWA 372
>gi|63003905 protein phosphatase 1 (formerly 2C)-like [Homo sapiens]
Length = 360
Score = 130 bits (327), Expect = 2e-30
Identities = 93/268 (34%), Positives = 143/268 (53%), Gaps = 23/268 (8%)
Query: 94 NVGCASQIGKRKENEDRF----DFAQLTDEVLYFAVYDGHGGPAAADFCHTHMEKCIMDL 149
NV S G+R EDRF D A T + F ++DGHGG AA++ + + + +
Sbjct: 92 NVAVYSIQGRRDHMEDRFEVLTDLANKTHPSI-FGIFDGHGGETAAEYVKSRLPEALKQH 150
Query: 150 LP-----KEKNL---ETLLTLAFLEIDKAFSSHARLSADATLLTSGTTATVALLRDGIEL 201
L KE ++ +T+L L ID+ +S D +GTT +ALL D +L
Sbjct: 151 LQDYEKDKENSVLSYQTILEQQILSIDREMLEKLTVSYDE----AGTTCLIALLSDK-DL 205
Query: 202 VVASVGDSRAILCRK-GKPMKLTIDHTPERKDEKERIKKCGGFVAWNSLGQPHVNGRLAM 260
VA+VGDSR +LC K G + L+ DH P + E++RIK+ GGF+++N G V G LAM
Sbjct: 206 TVANVGDSRGVLCDKDGNAIPLSHDHKPYQLKERKRIKRAGGFISFN--GSWRVQGILAM 263
Query: 261 TRSIGDLDLKT-SGVIAEPETKRIKLHHADDSFLVLTTDGINFMVNSQEICDFVNQ-CHD 318
+RS+GD LK + VI +P+ L F++L +DG+ +++E F+ + +
Sbjct: 264 SRSLGDYPLKNLNVVIPDPDILTFDLDKLQPEFMILASDGLWDAFSNEEAVRFIKERLDE 323
Query: 319 PNEAAHAVTEQAIQYGTEDNSTAVVVPF 346
P+ A ++ Q+ G DN T +VV F
Sbjct: 324 PHFGAKSIVLQSFYRGCPDNITVMVVKF 351
>gi|13540531 integrin-linked kinase-associated protein phosphatase
2C [Homo sapiens]
Length = 392
Score = 112 bits (279), Expect = 7e-25
Identities = 83/262 (31%), Positives = 130/262 (49%), Gaps = 37/262 (14%)
Query: 114 AQLTDEVLYFAVYDGHGGPAAADFCHTHMEKCIMDLLPK------EKNLETLLTLAFLEI 167
+ L V YFAV+DGHGG A+ F ++ + ++ PK EK ++ L F
Sbjct: 139 SSLITRVSYFAVFDGHGGIRASKFAAQNLHQNLIRKFPKGDVISVEKTVKRCLLDTFKHT 198
Query: 168 DKAFSSHARLSADATLLTSGTTATVALLRDGIELVVASVGDSRAILCR------KGKPMK 221
D+ F A S+ G+TAT L D I L +A++GDSRAILCR K +
Sbjct: 199 DEEFLKQA--SSQKPAWKDGSTATCVLAVDNI-LYIANLGDSRAILCRYNEESQKHAALS 255
Query: 222 LTIDHTPERKDEKERIKKCGGFVAWNSLGQPHVNGRLAMTRSIGDLDLKTSGVIAEPETK 281
L+ +H P + +E+ RI+K GG ++ V G L ++RSIGD K GV + P+ +
Sbjct: 256 LSKEHNPTQYEERMRIQKAGG-----NVRDGRVLGVLEVSRSIGDGQYKRCGVTSVPDIR 310
Query: 282 RIKLHHADDSFLVLTTDGINFMVNSQEICDFVNQCHDPNE----------------AAHA 325
R +L +D F++L DG+ + +E +F+ C + + A +
Sbjct: 311 RCQL-TPNDRFILLACDGLFKVFTPEEAVNFILSCLEDEKIQTREGKSAADARYEAACNR 369
Query: 326 VTEQAIQYGTEDNSTAVVVPFG 347
+ +A+Q G+ DN T +VV G
Sbjct: 370 LANKAVQRGSADNVTVMVVRIG 391
>gi|10337595 protein phosphatase 1A isoform 1 [Homo sapiens]
Length = 382
Score = 111 bits (278), Expect = 9e-25
Identities = 88/277 (31%), Positives = 130/277 (46%), Gaps = 36/277 (12%)
Query: 96 GCASQIGKRKENEDR----FDFAQLTDEVLYFAVYDGHGGPAAADFCHTHMEKCIMDL-- 149
G +S G R E ED + +FAVYDGH G A +C H+ I +
Sbjct: 25 GLSSMQGWRVEMEDAHTAVIGLPSGLESWSFFAVYDGHAGSQVAKYCCEHLLDHITNNQD 84
Query: 150 ------LPKEKNLETLLTLAFLEIDKAFS--SHARLSADATLLTSGTTATVALLRDGIEL 201
P +N++ + FLEID+ S + AD SG+TA V +L
Sbjct: 85 FKGSAGAPSVENVKNGIRTGFLEIDEHMRVMSEKKHGADR----SGSTA-VGVLISPQHT 139
Query: 202 VVASVGDSRAILCRKGKPMKLTIDHTPERKDEKERIKKCGGFVAWNSLGQPHVNGRLAMT 261
+ GDSR +LCR K T DH P EKERI+ GG S+ VNG LA++
Sbjct: 140 YFINCGDSRGLLCRNRKVHFFTQDHKPSNPLEKERIQNAGG-----SVMIQRVNGSLAVS 194
Query: 262 RSIGDLDLK-------TSGVIA-EPETKRIKLHHADDSFLVLTTDGINFMVNSQEICDFV 313
R++GD D K T +++ EPE I+ DD F++L DGI ++ ++E+CDFV
Sbjct: 195 RALGDFDYKCVHGKGPTEQLVSPEPEVHDIERSEEDDQFIILACDGIWDVMGNEELCDFV 254
Query: 314 NQ----CHDPNEAAHAVTEQAIQYGTEDNSTAVVVPF 346
D + + V + + G+ DN + +++ F
Sbjct: 255 RSRLEVTDDLEKVCNEVVDTCLYKGSRDNMSVILICF 291
>gi|29557855 protein phosphatase 1A isoform 2 [Homo sapiens]
Length = 324
Score = 111 bits (278), Expect = 9e-25
Identities = 88/277 (31%), Positives = 130/277 (46%), Gaps = 36/277 (12%)
Query: 96 GCASQIGKRKENEDR----FDFAQLTDEVLYFAVYDGHGGPAAADFCHTHMEKCIMDL-- 149
G +S G R E ED + +FAVYDGH G A +C H+ I +
Sbjct: 25 GLSSMQGWRVEMEDAHTAVIGLPSGLESWSFFAVYDGHAGSQVAKYCCEHLLDHITNNQD 84
Query: 150 ------LPKEKNLETLLTLAFLEIDKAFS--SHARLSADATLLTSGTTATVALLRDGIEL 201
P +N++ + FLEID+ S + AD SG+TA V +L
Sbjct: 85 FKGSAGAPSVENVKNGIRTGFLEIDEHMRVMSEKKHGADR----SGSTA-VGVLISPQHT 139
Query: 202 VVASVGDSRAILCRKGKPMKLTIDHTPERKDEKERIKKCGGFVAWNSLGQPHVNGRLAMT 261
+ GDSR +LCR K T DH P EKERI+ GG S+ VNG LA++
Sbjct: 140 YFINCGDSRGLLCRNRKVHFFTQDHKPSNPLEKERIQNAGG-----SVMIQRVNGSLAVS 194
Query: 262 RSIGDLDLK-------TSGVIA-EPETKRIKLHHADDSFLVLTTDGINFMVNSQEICDFV 313
R++GD D K T +++ EPE I+ DD F++L DGI ++ ++E+CDFV
Sbjct: 195 RALGDFDYKCVHGKGPTEQLVSPEPEVHDIERSEEDDQFIILACDGIWDVMGNEELCDFV 254
Query: 314 NQ----CHDPNEAAHAVTEQAIQYGTEDNSTAVVVPF 346
D + + V + + G+ DN + +++ F
Sbjct: 255 RSRLEVTDDLEKVCNEVVDTCLYKGSRDNMSVILICF 291
>gi|193211600 protein phosphatase 1A isoform 3 [Homo sapiens]
Length = 455
Score = 111 bits (278), Expect = 9e-25
Identities = 88/277 (31%), Positives = 130/277 (46%), Gaps = 36/277 (12%)
Query: 96 GCASQIGKRKENEDR----FDFAQLTDEVLYFAVYDGHGGPAAADFCHTHMEKCIMDL-- 149
G +S G R E ED + +FAVYDGH G A +C H+ I +
Sbjct: 98 GLSSMQGWRVEMEDAHTAVIGLPSGLESWSFFAVYDGHAGSQVAKYCCEHLLDHITNNQD 157
Query: 150 ------LPKEKNLETLLTLAFLEIDKAFS--SHARLSADATLLTSGTTATVALLRDGIEL 201
P +N++ + FLEID+ S + AD SG+TA V +L
Sbjct: 158 FKGSAGAPSVENVKNGIRTGFLEIDEHMRVMSEKKHGADR----SGSTA-VGVLISPQHT 212
Query: 202 VVASVGDSRAILCRKGKPMKLTIDHTPERKDEKERIKKCGGFVAWNSLGQPHVNGRLAMT 261
+ GDSR +LCR K T DH P EKERI+ GG S+ VNG LA++
Sbjct: 213 YFINCGDSRGLLCRNRKVHFFTQDHKPSNPLEKERIQNAGG-----SVMIQRVNGSLAVS 267
Query: 262 RSIGDLDLK-------TSGVIA-EPETKRIKLHHADDSFLVLTTDGINFMVNSQEICDFV 313
R++GD D K T +++ EPE I+ DD F++L DGI ++ ++E+CDFV
Sbjct: 268 RALGDFDYKCVHGKGPTEQLVSPEPEVHDIERSEEDDQFIILACDGIWDVMGNEELCDFV 327
Query: 314 NQ----CHDPNEAAHAVTEQAIQYGTEDNSTAVVVPF 346
D + + V + + G+ DN + +++ F
Sbjct: 328 RSRLEVTDDLEKVCNEVVDTCLYKGSRDNMSVILICF 364
>gi|30089948 protein phosphatase 1E [Homo sapiens]
Length = 755
Score = 110 bits (276), Expect = 2e-24
Identities = 82/234 (35%), Positives = 121/234 (51%), Gaps = 18/234 (7%)
Query: 118 DEVLYFAVYDGHGGPAAADFC--HTHMEKCIMDLLPKEKNLETLLTLAFLEIDKAFSSHA 175
+E YFAV+DGHGG AA + H H+ ++ P + L AF D+ F A
Sbjct: 264 EEQAYFAVFDGHGGVDAAIYASIHLHVNLVRQEMFPHDP--AEALCRAFRVTDERFVQKA 321
Query: 176 RLSADATLLTSGTTATVALLRDGIELVVASVGDSRAILCRKGKPMKLTIDHTPERKDEKE 235
+ L GTT V +R G L VA VGDS+ +L RKG+ ++L H P+R+DEK+
Sbjct: 322 ARES----LRCGTTGVVTFIR-GNMLHVAWVGDSQVMLVRKGQAVELMKPHKPDREDEKQ 376
Query: 236 RIKKCGGFVAWNSLGQPHVNGRLAMTRSIGDLDLKTSGVIAEPETKRIKLHHADDSFLVL 295
RI+ GG V W G VNG L+++R+IGD + K + + ++ L +D +L+L
Sbjct: 377 RIEALGGCVVW--FGAWRVNGSLSVSRAIGDAEHKPY-ICGDADSASTVLDGTED-YLIL 432
Query: 296 TTDGINFMVNSQE----ICDFVNQCH-DPNEAAHAVTEQAIQYGTEDNSTAVVV 344
DG VN E + D + + + D + AH + A G+ DN T +VV
Sbjct: 433 ACDGFYDTVNPDEAVKVVSDHLKENNGDSSMVAHKLVASARDAGSSDNITVIVV 486
>gi|7661862 protein phosphatase 1F [Homo sapiens]
Length = 454
Score = 103 bits (257), Expect = 2e-22
Identities = 95/258 (36%), Positives = 130/258 (50%), Gaps = 29/258 (11%)
Query: 104 RKENEDRF----DFAQL---TDEV--LYFAVYDGHGGPAAADFC--HTHMEKCIMDLLPK 152
R++ EDR F QL +D V YFAV+DGHGG AA + H H LP
Sbjct: 166 RRKMEDRHVSLPSFNQLFGLSDPVNRAYFAVFDGHGGVDAARYAAVHVHTNAARQPELPT 225
Query: 153 EKNLETLLTLAFLEIDKAFSSHARLSADATLLTSGTTATVALLRDGIELVVASVGDSRAI 212
+ E L AF D+ F A+ L SGTT AL+ G L VA +GDS+ I
Sbjct: 226 DP--EGALREAFRRTDQMFLRKAKRER----LQSGTTGVCALIA-GATLHVAWLGDSQVI 278
Query: 213 LCRKGKPMKLTIDHTPERKDEKERIKKCGGFVAWNSLGQPHVNGRLAMTRSIGDLDLKTS 272
L ++G+ +KL H PER+DEK RI+ GGFV+ + VNG LA++R+IGD+ K
Sbjct: 279 LVQQGQVVKLMEPHRPERQDEKARIEALGGFVSHMDCWR--VNGTLAVSRAIGDVFQKPY 336
Query: 273 GVIAEPETKRIKLHHADDSFLVLTTDGINFMVNSQEICDFVNQCHDPNE------AAHAV 326
V E + L ++D +L+L DG +V QE+ V Q H + A +
Sbjct: 337 -VSGEADAASRALTGSED-YLLLACDGFFDVVPHQEVVGLV-QSHLTRQQGSGLRVAEEL 393
Query: 327 TEQAIQYGTEDNSTAVVV 344
A + G+ DN T +VV
Sbjct: 394 VAAARERGSHDNITVMVV 411
>gi|75813620 protein phosphatase 1B isoform 5 [Homo sapiens]
Length = 380
Score = 101 bits (252), Expect = 9e-22
Identities = 85/280 (30%), Positives = 131/280 (46%), Gaps = 38/280 (13%)
Query: 96 GCASQIGKRKENEDRFD----FAQLTDEVLYFAVYDGHGGPAAADFCHTHMEKCIMD--- 148
G +S G R E ED ++ +FAVYDGH G A++C TH+ + I
Sbjct: 25 GLSSMQGWRVEMEDAHTAVVGIPHGLEDWSFFAVYDGHAGSRVANYCSTHLLEHITTNED 84
Query: 149 ----------LLPKEKNLETLLTLAFLEIDKAFSSHARLSADATLLTSGTTATVALLRDG 198
L +N++ + FL+ID+ + + L SG+TA V ++
Sbjct: 85 FRAAGKSGSALELSVENVKNGIRTGFLKIDEYMRNFSDLRNGMD--RSGSTA-VGVMISP 141
Query: 199 IELVVASVGDSRAILCRKGKPMKLTIDHTPERKDEKERIKKCGGFVAWNSLGQPHVNGRL 258
+ + GDSRA+L R G+ T DH P EKERI+ GG S+ VNG L
Sbjct: 142 KHIYFINCGDSRAVLYRNGQVCFSTQDHKPCNPREKERIQNAGG-----SVMIQRVNGSL 196
Query: 259 AMTRSIGDLDLKTSG--------VIAEPETKRIKLHHADDSFLVLTTDGINFMVNSQEIC 310
A++R++GD D K V EPE I L +D F++L DGI +++++E+C
Sbjct: 197 AVSRALGDYDYKCVDGKGPTEQLVSPEPEVYEI-LRAEEDEFIILACDGIWDVMSNEELC 255
Query: 311 DFVNQ----CHDPNEAAHAVTEQAIQYGTEDNSTAVVVPF 346
++V D + V + + G+ DN + V+V F
Sbjct: 256 EYVKSRLEVSDDLENVCNWVVDTCLHKGSRDNMSIVLVCF 295
>gi|75813618 protein phosphatase 1B isoform 4 [Homo sapiens]
Length = 327
Score = 101 bits (252), Expect = 9e-22
Identities = 85/280 (30%), Positives = 131/280 (46%), Gaps = 38/280 (13%)
Query: 96 GCASQIGKRKENEDRFD----FAQLTDEVLYFAVYDGHGGPAAADFCHTHMEKCIMD--- 148
G +S G R E ED ++ +FAVYDGH G A++C TH+ + I
Sbjct: 25 GLSSMQGWRVEMEDAHTAVVGIPHGLEDWSFFAVYDGHAGSRVANYCSTHLLEHITTNED 84
Query: 149 ----------LLPKEKNLETLLTLAFLEIDKAFSSHARLSADATLLTSGTTATVALLRDG 198
L +N++ + FL+ID+ + + L SG+TA V ++
Sbjct: 85 FRAAGKSGSALELSVENVKNGIRTGFLKIDEYMRNFSDLRNGMD--RSGSTA-VGVMISP 141
Query: 199 IELVVASVGDSRAILCRKGKPMKLTIDHTPERKDEKERIKKCGGFVAWNSLGQPHVNGRL 258
+ + GDSRA+L R G+ T DH P EKERI+ GG S+ VNG L
Sbjct: 142 KHIYFINCGDSRAVLYRNGQVCFSTQDHKPCNPREKERIQNAGG-----SVMIQRVNGSL 196
Query: 259 AMTRSIGDLDLKTSG--------VIAEPETKRIKLHHADDSFLVLTTDGINFMVNSQEIC 310
A++R++GD D K V EPE I L +D F++L DGI +++++E+C
Sbjct: 197 AVSRALGDYDYKCVDGKGPTEQLVSPEPEVYEI-LRAEEDEFIILACDGIWDVMSNEELC 255
Query: 311 DFVNQ----CHDPNEAAHAVTEQAIQYGTEDNSTAVVVPF 346
++V D + V + + G+ DN + V+V F
Sbjct: 256 EYVKSRLEVSDDLENVCNWVVDTCLHKGSRDNMSIVLVCF 295
>gi|29558022 protein phosphatase 1B isoform 2 [Homo sapiens]
Length = 387
Score = 101 bits (252), Expect = 9e-22
Identities = 85/280 (30%), Positives = 131/280 (46%), Gaps = 38/280 (13%)
Query: 96 GCASQIGKRKENEDRFD----FAQLTDEVLYFAVYDGHGGPAAADFCHTHMEKCIMD--- 148
G +S G R E ED ++ +FAVYDGH G A++C TH+ + I
Sbjct: 25 GLSSMQGWRVEMEDAHTAVVGIPHGLEDWSFFAVYDGHAGSRVANYCSTHLLEHITTNED 84
Query: 149 ----------LLPKEKNLETLLTLAFLEIDKAFSSHARLSADATLLTSGTTATVALLRDG 198
L +N++ + FL+ID+ + + L SG+TA V ++
Sbjct: 85 FRAAGKSGSALELSVENVKNGIRTGFLKIDEYMRNFSDLRNGMD--RSGSTA-VGVMISP 141
Query: 199 IELVVASVGDSRAILCRKGKPMKLTIDHTPERKDEKERIKKCGGFVAWNSLGQPHVNGRL 258
+ + GDSRA+L R G+ T DH P EKERI+ GG S+ VNG L
Sbjct: 142 KHIYFINCGDSRAVLYRNGQVCFSTQDHKPCNPREKERIQNAGG-----SVMIQRVNGSL 196
Query: 259 AMTRSIGDLDLKTSG--------VIAEPETKRIKLHHADDSFLVLTTDGINFMVNSQEIC 310
A++R++GD D K V EPE I L +D F++L DGI +++++E+C
Sbjct: 197 AVSRALGDYDYKCVDGKGPTEQLVSPEPEVYEI-LRAEEDEFIILACDGIWDVMSNEELC 255
Query: 311 DFVNQ----CHDPNEAAHAVTEQAIQYGTEDNSTAVVVPF 346
++V D + V + + G+ DN + V+V F
Sbjct: 256 EYVKSRLEVSDDLENVCNWVVDTCLHKGSRDNMSIVLVCF 295
>gi|4505995 protein phosphatase 1B isoform 1 [Homo sapiens]
Length = 479
Score = 101 bits (252), Expect = 9e-22
Identities = 85/280 (30%), Positives = 131/280 (46%), Gaps = 38/280 (13%)
Query: 96 GCASQIGKRKENEDRFD----FAQLTDEVLYFAVYDGHGGPAAADFCHTHMEKCIMD--- 148
G +S G R E ED ++ +FAVYDGH G A++C TH+ + I
Sbjct: 25 GLSSMQGWRVEMEDAHTAVVGIPHGLEDWSFFAVYDGHAGSRVANYCSTHLLEHITTNED 84
Query: 149 ----------LLPKEKNLETLLTLAFLEIDKAFSSHARLSADATLLTSGTTATVALLRDG 198
L +N++ + FL+ID+ + + L SG+TA V ++
Sbjct: 85 FRAAGKSGSALELSVENVKNGIRTGFLKIDEYMRNFSDLRNGMD--RSGSTA-VGVMISP 141
Query: 199 IELVVASVGDSRAILCRKGKPMKLTIDHTPERKDEKERIKKCGGFVAWNSLGQPHVNGRL 258
+ + GDSRA+L R G+ T DH P EKERI+ GG S+ VNG L
Sbjct: 142 KHIYFINCGDSRAVLYRNGQVCFSTQDHKPCNPREKERIQNAGG-----SVMIQRVNGSL 196
Query: 259 AMTRSIGDLDLKTSG--------VIAEPETKRIKLHHADDSFLVLTTDGINFMVNSQEIC 310
A++R++GD D K V EPE I L +D F++L DGI +++++E+C
Sbjct: 197 AVSRALGDYDYKCVDGKGPTEQLVSPEPEVYEI-LRAEEDEFIILACDGIWDVMSNEELC 255
Query: 311 DFVNQ----CHDPNEAAHAVTEQAIQYGTEDNSTAVVVPF 346
++V D + V + + G+ DN + V+V F
Sbjct: 256 EYVKSRLEVSDDLENVCNWVVDTCLHKGSRDNMSIVLVCF 295
>gi|122937199 protein phosphatase 1B-like [Homo sapiens]
Length = 430
Score = 84.0 bits (206), Expect = 2e-16
Identities = 76/240 (31%), Positives = 108/240 (45%), Gaps = 28/240 (11%)
Query: 123 FAVYDGHGGPAAADFCHTHMEKCIMDLLPKE----KNLETLLTLAFLEIDKAFSSHARLS 178
FAV DGHGG AA F H+ ++ L E + + L AFL D+ S
Sbjct: 99 FAVLDGHGGARAARFGARHLPGHVLQELGPEPSEPEGVREALRRAFLSADERLRS----- 153
Query: 179 ADATLLTSGTTATVALLRDGIELVVASVGDSRAILCRKGKPMKLTIDHTPERKDEKERIK 238
+ T G TA V L+ L +A GDSRA+L R G T DH P R E+ERI
Sbjct: 154 LWPRVETGGCTAVVLLVSPRF-LYLAHCGDSRAVLSRAGAVAFSTEDHRPLRPRERERIH 212
Query: 239 KCGGFVAWNSLGQPHVNGRLAMTRSIGDLDLKTSG--------VIAEPETKRIKLHHADD 290
GG ++ + V G LA++R++GD K + V AEPE + A+D
Sbjct: 213 AAGG-----TIRRRRVEGSLAVSRALGDFTYKEAPGRPPELQLVSAEPEVAAL-ARQAED 266
Query: 291 SFLVLTTDGINFMVNSQEICDFVNQCHDPNEAAHAVTEQAIQ----YGTEDNSTAVVVPF 346
F++L +DG+ V+ + V A + Q + G+ DN T ++V F
Sbjct: 267 EFMLLASDGVWDTVSGAALAGLVASRLRLGLAPELLCAQLLDTCLCKGSLDNMTCILVCF 326
>gi|4505999 protein phosphatase 1G [Homo sapiens]
Length = 546
Score = 83.6 bits (205), Expect = 3e-16
Identities = 54/136 (39%), Positives = 79/136 (58%), Gaps = 14/136 (10%)
Query: 186 SGTTATVALLRDGIELVVASVGDSRAILCRKGKPMKLTIDHTPERKDEKERIKKCGGFVA 245
SGTTA VAL+R G +L+VA+ GDSR ++ GK + ++ DH PE + E RIK GG V
Sbjct: 327 SGTTAVVALIR-GKQLIVANAGDSRCVVSEAGKALDMSYDHKPEDEVELARIKNAGGKVT 385
Query: 246 WNSLGQPHVNGRLAMTRSIGD--------LDLKTSGVIAEPETKRIKLHHADDSFLVLTT 297
+ VNG L ++R+IGD L + + A P+ K + L D F+V+
Sbjct: 386 MDG----RVNGGLNLSRAIGDHFYKRNKNLPPEEQMISALPDIKVLTLTD-DHEFMVIAC 440
Query: 298 DGINFMVNSQEICDFV 313
DGI +++SQE+ DF+
Sbjct: 441 DGIWNVMSSQEVVDFI 456
Score = 42.0 bits (97), Expect = 9e-04
Identities = 31/87 (35%), Positives = 42/87 (48%), Gaps = 3/87 (3%)
Query: 84 GKPIPKISLENVGCASQIGKRKENEDRFD-FAQLTDEVLYFAVYDGHGGPAAADFCHTHM 142
G P++ L G ++ G R ED + +L E F+VYDGHGG A +C ++
Sbjct: 17 GVGAPRLPLP-YGFSAMQGWRVSMEDAHNCIPELDSETAMFSVYDGHGGEEVALYCAKYL 75
Query: 143 EKCIMDLLP-KEKNLETLLTLAFLEID 168
I D KE L+ L AFL ID
Sbjct: 76 PDIIKDQKAYKEGKLQKALEDAFLAID 102
>gi|29826282 protein phosphatase 1G [Homo sapiens]
Length = 546
Score = 83.6 bits (205), Expect = 3e-16
Identities = 54/136 (39%), Positives = 79/136 (58%), Gaps = 14/136 (10%)
Query: 186 SGTTATVALLRDGIELVVASVGDSRAILCRKGKPMKLTIDHTPERKDEKERIKKCGGFVA 245
SGTTA VAL+R G +L+VA+ GDSR ++ GK + ++ DH PE + E RIK GG V
Sbjct: 327 SGTTAVVALIR-GKQLIVANAGDSRCVVSEAGKALDMSYDHKPEDEVELARIKNAGGKVT 385
Query: 246 WNSLGQPHVNGRLAMTRSIGD--------LDLKTSGVIAEPETKRIKLHHADDSFLVLTT 297
+ VNG L ++R+IGD L + + A P+ K + L D F+V+
Sbjct: 386 MDG----RVNGGLNLSRAIGDHFYKRNKNLPPEEQMISALPDIKVLTLTD-DHEFMVIAC 440
Query: 298 DGINFMVNSQEICDFV 313
DGI +++SQE+ DF+
Sbjct: 441 DGIWNVMSSQEVVDFI 456
Score = 42.0 bits (97), Expect = 9e-04
Identities = 31/87 (35%), Positives = 42/87 (48%), Gaps = 3/87 (3%)
Query: 84 GKPIPKISLENVGCASQIGKRKENEDRFD-FAQLTDEVLYFAVYDGHGGPAAADFCHTHM 142
G P++ L G ++ G R ED + +L E F+VYDGHGG A +C ++
Sbjct: 17 GVGAPRLPLP-YGFSAMQGWRVSMEDAHNCIPELDSETAMFSVYDGHGGEEVALYCAKYL 75
Query: 143 EKCIMDLLP-KEKNLETLLTLAFLEID 168
I D KE L+ L AFL ID
Sbjct: 76 PDIIKDQKAYKEGKLQKALEDAFLAID 102
>gi|4505997 protein phosphatase 1D [Homo sapiens]
Length = 605
Score = 70.9 bits (172), Expect = 2e-12
Identities = 75/253 (29%), Positives = 111/253 (43%), Gaps = 53/253 (20%)
Query: 120 VLYFAVYDGHGGPAAADFCHTHMEKCIMDLLPKEKNLET--------LLTLAFLEIDKA- 170
V +FAV DGHGG AA F H + + K+K + + FL A
Sbjct: 98 VAFFAVCDGHGGREAAQFAREH----LWGFIKKQKGFTSSEPAKVCAAIRKGFLACHLAM 153
Query: 171 FSSHARLSADATLL--TSGTTATVALLRDGIELVVASVGDSRAILCRKGKP-------MK 221
+ A T L TSGTTA+V ++R G+++ VA VGDS +L + P ++
Sbjct: 154 WKKLAEWPKTMTGLPSTSGTTASVVIIR-GMKMYVAHVGDSGVVLGIQDDPKDDFVRAVE 212
Query: 222 LTIDHTPERKDEKERIKKCGGF---------VAWNSLGQPHVNGR------------LAM 260
+T DH PE E+ERI+ GG V W H NG LA+
Sbjct: 213 VTQDHKPELPKERERIEGLGGSVMNKSGVNRVVWKRPRLTH-NGPVRRSTVIDQIPFLAV 271
Query: 261 TRSIGDL---DLKTSGVIA--EPETKRIKLHHADDSFLVLTTDGINFMVNSQEICDFVNQ 315
R++GDL D + + EP+T L +++L +DG+ M+ Q D ++
Sbjct: 272 ARALGDLWSYDFFSGEFVVSPEPDTSVHTLDPQKHKYIILGSDGLWNMIPPQ---DAISM 328
Query: 316 CHDPNEAAHAVTE 328
C D E + + E
Sbjct: 329 CQDQEEKKYLMGE 341
>gi|37221175 PH domain and leucine rich repeat protein phosphatase
[Homo sapiens]
Length = 1205
Score = 61.2 bits (147), Expect = 1e-09
Identities = 59/232 (25%), Positives = 98/232 (42%), Gaps = 20/232 (8%)
Query: 119 EVLYFAVYDGHGGPAAADFCHTHMEKCIMDLLPKEKNLETLLTLAFLEIDKAFSSHARLS 178
E LY V+DG M + + L K KN E + F+ + + + +
Sbjct: 691 EALY-GVFDGDRNVEVPYLLQCTMSDILAEELQKTKNEEEYMVNTFIVMQRKLGTAGQKL 749
Query: 179 ADATLLTSGTTATVALLRDGIE------LVVASVGDSRAILCRKGKPMKLTIDHTPERKD 232
A +L + D ++ L A+VG + +LCR GKP+ L+ + ++
Sbjct: 750 GGAAVLCH-------IKHDPVDPGGSFTLTSANVGKCQTVLCRNGKPLPLSRSYIMSCEE 802
Query: 233 EKERIKKCGGFVAWNSLGQPHVNGRLAMTRSIGDLDLKTSGVIAEPETKRIKLHHADDSF 292
E +RIK+ + + VNG TR +G L S V+ P + + L D F
Sbjct: 803 ELKRIKQHKAIITEDG----KVNGVTESTRILGYTFLHPS-VVPRPHVQSVLL-TPQDEF 856
Query: 293 LVLTTDGINFMVNSQEICDFVNQCHDPNEAAHAVTEQAIQYGTEDNSTAVVV 344
+L + G+ ++ +E + V D AA + A YG D+ +AVVV
Sbjct: 857 FILGSKGLWDSLSVEEAVEAVRNVPDALAAAKKLCTLAQSYGCHDSISAVVV 908
>gi|65301141 PH domain and leucine rich repeat protein
phosphatase-like [Homo sapiens]
Length = 1323
Score = 51.2 bits (121), Expect = 1e-06
Identities = 55/230 (23%), Positives = 94/230 (40%), Gaps = 22/230 (9%)
Query: 123 FAVYDGHGGPAAADFCHTHMEKCIMDLLPKEKNLETLLTLAFLEIDKAFSSHARLSADAT 182
+ ++DG M +++ + + N + FL SH +L
Sbjct: 816 YGMFDGDRNEELPRLLQCTMADVLLEEVQQSTNDTVFMANTFLV------SHRKLGMAGQ 869
Query: 183 LLTSGTTATVALLR-------DGIELVVASVGDSRAILCRKGKPMKLT-IDHTPERKDEK 234
L G++A + +R L VA+VG +A+LCR GKP+ L+ + + +E
Sbjct: 870 KL--GSSALLCYIRPDTADPASSFSLTVANVGTCQAVLCRGGKPVPLSKVFSLEQDPEEA 927
Query: 235 ERIKKCGGFVAWNSLGQPHVNGRLAMTRSIGDLDLKTSGVIAEPETKRIKLHHADDSFLV 294
+R+K + ++ VNG TR +G L ++ +P L D L+
Sbjct: 928 QRVKDQKAIITEDN----KVNGVTCCTRMLGCTYL-YPWILPKPHISSTPL-TIQDELLI 981
Query: 295 LTTDGINFMVNSQEICDFVNQCHDPNEAAHAVTEQAIQYGTEDNSTAVVV 344
L + ++ E + V DP AA + A YG +DN A+VV
Sbjct: 982 LGNKALWEHLSYTEAVNAVRHVQDPLAAAKKLCTLAQSYGCQDNVGAMVV 1031
>gi|5174703 mitogen-activated protein kinase kinase kinase 7
interacting protein 1 isoform alpha [Homo sapiens]
Length = 504
Score = 48.9 bits (115), Expect = 7e-06
Identities = 42/134 (31%), Positives = 67/134 (50%), Gaps = 20/134 (14%)
Query: 184 LTSGTTATVALLRDGIELVVASVGDSRAILCRKG----KPMKLTIDHTPERKDEKERIKK 239
++ G A VA+L + +L VA+VG +RA+LC+ + +L +DHT E +DE R+ +
Sbjct: 162 ISGGAMAVVAVLLNN-KLYVANVGTNRALLCKSTVDGLQVTQLNVDHTTENEDELFRLSQ 220
Query: 240 CGGFVAWNSLGQPHVNGRLAMTRSIG---------DLDL----KTSGVIAEPETKRIKLH 286
G + + Q + TR IG D+DL K+ +IAEPE +
Sbjct: 221 LG--LDAGKIKQVGIICGQESTRRIGDYKVKYGYTDIDLLSAAKSKPIIAEPEIHGAQPL 278
Query: 287 HADDSFLVLTTDGI 300
FLVL ++G+
Sbjct: 279 DGVTGFLVLMSEGL 292
>gi|41281798 mitogen-activated protein kinase kinase kinase 7
interacting protein 1 isoform beta [Homo sapiens]
Length = 462
Score = 48.9 bits (115), Expect = 7e-06
Identities = 42/134 (31%), Positives = 67/134 (50%), Gaps = 20/134 (14%)
Query: 184 LTSGTTATVALLRDGIELVVASVGDSRAILCRKG----KPMKLTIDHTPERKDEKERIKK 239
++ G A VA+L + +L VA+VG +RA+LC+ + +L +DHT E +DE R+ +
Sbjct: 162 ISGGAMAVVAVLLNN-KLYVANVGTNRALLCKSTVDGLQVTQLNVDHTTENEDELFRLSQ 220
Query: 240 CGGFVAWNSLGQPHVNGRLAMTRSIG---------DLDL----KTSGVIAEPETKRIKLH 286
G + + Q + TR IG D+DL K+ +IAEPE +
Sbjct: 221 LG--LDAGKIKQVGIICGQESTRRIGDYKVKYGYTDIDLLSAAKSKPIIAEPEIHGAQPL 278
Query: 287 HADDSFLVLTTDGI 300
FLVL ++G+
Sbjct: 279 DGVTGFLVLMSEGL 292
>gi|45439339 pyruvate dehyrogenase phosphatase catalytic subunit 1
isoform 3 precursor [Homo sapiens]
Length = 537
Score = 44.7 bits (104), Expect = 1e-04
Identities = 55/207 (26%), Positives = 88/207 (42%), Gaps = 48/207 (23%)
Query: 155 NLETLLTLAFLEIDKAFSSHARLSADATLLT--------SGTTATVALLRDGIELVVASV 206
+++ L AF +D S A++ + L SG TA VA + DG++L VA+
Sbjct: 231 DVKEALINAFKRLDNDISLEAQVGDPNSFLNYLVLRVAFSGATACVAHV-DGVDLHVANT 289
Query: 207 GDSRAILCRKGK-----PMKLTIDHTPERKDEKERIK-KCGGFVAWNSLGQPHVNGRLAM 260
GDSRA+L + + + L+ DH + + E ER+K + A + + Q + G L
Sbjct: 290 GDSRAMLGVQEEDGSWSAVTLSNDHNAQNERELERLKLEHPKSEAKSVVKQDRLLGLLMP 349
Query: 261 TRSIGDLDLKTS--------------------------------GVIAEPETKRIKLHHA 288
R+ GD+ K S + AEPE +L
Sbjct: 350 FRAFGDVKFKWSIDLQKRVIESGPDQLNDNEYTKFIPPNYHTPPYLTAEPEVTYHRL-RP 408
Query: 289 DDSFLVLTTDGINFMVNSQEICDFVNQ 315
D FLVL TDG+ ++ Q++ V +
Sbjct: 409 QDKFLVLATDGLWETMHRQDVVRIVGE 435
>gi|239985428 pyruvate dehyrogenase phosphatase catalytic subunit 1
isoform 3 precursor [Homo sapiens]
Length = 537
Score = 44.7 bits (104), Expect = 1e-04
Identities = 55/207 (26%), Positives = 88/207 (42%), Gaps = 48/207 (23%)
Query: 155 NLETLLTLAFLEIDKAFSSHARLSADATLLT--------SGTTATVALLRDGIELVVASV 206
+++ L AF +D S A++ + L SG TA VA + DG++L VA+
Sbjct: 231 DVKEALINAFKRLDNDISLEAQVGDPNSFLNYLVLRVAFSGATACVAHV-DGVDLHVANT 289
Query: 207 GDSRAILCRKGK-----PMKLTIDHTPERKDEKERIK-KCGGFVAWNSLGQPHVNGRLAM 260
GDSRA+L + + + L+ DH + + E ER+K + A + + Q + G L
Sbjct: 290 GDSRAMLGVQEEDGSWSAVTLSNDHNAQNERELERLKLEHPKSEAKSVVKQDRLLGLLMP 349
Query: 261 TRSIGDLDLKTS--------------------------------GVIAEPETKRIKLHHA 288
R+ GD+ K S + AEPE +L
Sbjct: 350 FRAFGDVKFKWSIDLQKRVIESGPDQLNDNEYTKFIPPNYHTPPYLTAEPEVTYHRL-RP 408
Query: 289 DDSFLVLTTDGINFMVNSQEICDFVNQ 315
D FLVL TDG+ ++ Q++ V +
Sbjct: 409 QDKFLVLATDGLWETMHRQDVVRIVGE 435
>gi|239985426 pyruvate dehyrogenase phosphatase catalytic subunit 1
isoform 2 [Homo sapiens]
Length = 562
Score = 44.7 bits (104), Expect = 1e-04
Identities = 55/207 (26%), Positives = 88/207 (42%), Gaps = 48/207 (23%)
Query: 155 NLETLLTLAFLEIDKAFSSHARLSADATLLT--------SGTTATVALLRDGIELVVASV 206
+++ L AF +D S A++ + L SG TA VA + DG++L VA+
Sbjct: 256 DVKEALINAFKRLDNDISLEAQVGDPNSFLNYLVLRVAFSGATACVAHV-DGVDLHVANT 314
Query: 207 GDSRAILCRKGK-----PMKLTIDHTPERKDEKERIK-KCGGFVAWNSLGQPHVNGRLAM 260
GDSRA+L + + + L+ DH + + E ER+K + A + + Q + G L
Sbjct: 315 GDSRAMLGVQEEDGSWSAVTLSNDHNAQNERELERLKLEHPKSEAKSVVKQDRLLGLLMP 374
Query: 261 TRSIGDLDLKTS--------------------------------GVIAEPETKRIKLHHA 288
R+ GD+ K S + AEPE +L
Sbjct: 375 FRAFGDVKFKWSIDLQKRVIESGPDQLNDNEYTKFIPPNYHTPPYLTAEPEVTYHRL-RP 433
Query: 289 DDSFLVLTTDGINFMVNSQEICDFVNQ 315
D FLVL TDG+ ++ Q++ V +
Sbjct: 434 QDKFLVLATDGLWETMHRQDVVRIVGE 460
>gi|239985422 pyruvate dehyrogenase phosphatase catalytic subunit 1
isoform 2 [Homo sapiens]
Length = 562
Score = 44.7 bits (104), Expect = 1e-04
Identities = 55/207 (26%), Positives = 88/207 (42%), Gaps = 48/207 (23%)
Query: 155 NLETLLTLAFLEIDKAFSSHARLSADATLLT--------SGTTATVALLRDGIELVVASV 206
+++ L AF +D S A++ + L SG TA VA + DG++L VA+
Sbjct: 256 DVKEALINAFKRLDNDISLEAQVGDPNSFLNYLVLRVAFSGATACVAHV-DGVDLHVANT 314
Query: 207 GDSRAILCRKGK-----PMKLTIDHTPERKDEKERIK-KCGGFVAWNSLGQPHVNGRLAM 260
GDSRA+L + + + L+ DH + + E ER+K + A + + Q + G L
Sbjct: 315 GDSRAMLGVQEEDGSWSAVTLSNDHNAQNERELERLKLEHPKSEAKSVVKQDRLLGLLMP 374
Query: 261 TRSIGDLDLKTS--------------------------------GVIAEPETKRIKLHHA 288
R+ GD+ K S + AEPE +L
Sbjct: 375 FRAFGDVKFKWSIDLQKRVIESGPDQLNDNEYTKFIPPNYHTPPYLTAEPEVTYHRL-RP 433
Query: 289 DDSFLVLTTDGINFMVNSQEICDFVNQ 315
D FLVL TDG+ ++ Q++ V +
Sbjct: 434 QDKFLVLATDGLWETMHRQDVVRIVGE 460
>gi|239985420 pyruvate dehyrogenase phosphatase catalytic subunit 1
isoform 1 [Homo sapiens]
Length = 596
Score = 44.7 bits (104), Expect = 1e-04
Identities = 55/207 (26%), Positives = 88/207 (42%), Gaps = 48/207 (23%)
Query: 155 NLETLLTLAFLEIDKAFSSHARLSADATLLT--------SGTTATVALLRDGIELVVASV 206
+++ L AF +D S A++ + L SG TA VA + DG++L VA+
Sbjct: 290 DVKEALINAFKRLDNDISLEAQVGDPNSFLNYLVLRVAFSGATACVAHV-DGVDLHVANT 348
Query: 207 GDSRAILCRKGK-----PMKLTIDHTPERKDEKERIK-KCGGFVAWNSLGQPHVNGRLAM 260
GDSRA+L + + + L+ DH + + E ER+K + A + + Q + G L
Sbjct: 349 GDSRAMLGVQEEDGSWSAVTLSNDHNAQNERELERLKLEHPKSEAKSVVKQDRLLGLLMP 408
Query: 261 TRSIGDLDLKTS--------------------------------GVIAEPETKRIKLHHA 288
R+ GD+ K S + AEPE +L
Sbjct: 409 FRAFGDVKFKWSIDLQKRVIESGPDQLNDNEYTKFIPPNYHTPPYLTAEPEVTYHRL-RP 467
Query: 289 DDSFLVLTTDGINFMVNSQEICDFVNQ 315
D FLVL TDG+ ++ Q++ V +
Sbjct: 468 QDKFLVLATDGLWETMHRQDVVRIVGE 494
>gi|149944715 protein phosphatase 1H (PP2C domain containing) [Homo
sapiens]
Length = 514
Score = 42.0 bits (97), Expect = 9e-04
Identities = 42/191 (21%), Positives = 78/191 (40%), Gaps = 60/191 (31%)
Query: 184 LTSGTTATVALLRDGIELVVASVGDSRAILCRKGKPMKLTIDHTPE-------------- 229
++ G TA + + G +L VA+ GDSRAI+ R G+ + ++ + TPE
Sbjct: 265 ISGGCTALIVICLLG-KLYVANAGDSRAIIIRNGEIIPMSSEFTPETERQRLQYLAFMQP 323
Query: 230 -------------RKDEKERIKKCGGFVAWNSLG---------------------QPHVN 255
R+ +++ + K + +N G + V
Sbjct: 324 HLLGNEFTHLEFPRRVQRKELGKKMLYRDFNMTGWAYKTIEDEDLKFPLIYGEGKKARVM 383
Query: 256 GRLAMTRSIGDLDLKTSG--------VIAEPETK---RIKLHHADDSFLVLTTDGINFMV 304
+ +TR +GD DLK + + PE + K H D L+L TDG+ ++
Sbjct: 384 ATIGVTRGLGDHDLKVHDSNIYIKPFLSSAPEVRIYDLSKYDHGSDDVLILATDGLWDVL 443
Query: 305 NSQEICDFVNQ 315
+++E+ + + Q
Sbjct: 444 SNEEVAEAITQ 454
>gi|41349497 pyruvate dehydrogenase phosphatase isoenzyme 2 [Homo
sapiens]
Length = 529
Score = 40.0 bits (92), Expect = 0.003
Identities = 47/186 (25%), Positives = 72/186 (38%), Gaps = 39/186 (20%)
Query: 165 LEIDKAFSSHARLSADATLLTSGTTATVALLRDGIELVVASVGDSRAILCRKGKP----- 219
LEI + + SG TA +A + DGI L VA+ GD RAIL +
Sbjct: 244 LEIQAPLEDEVTRNLSLQVAFSGATACMAHV-DGIHLHVANAGDCRAILGVQEDNGMWSC 302
Query: 220 MKLTIDHTPERKDEKERIKK----------------CGGFVAWNSLGQPHVNGRLAMTRS 263
+ LT DH + E R+K+ G + + G + + RS
Sbjct: 303 LPLTRDHNAWNQAELSRLKREHPESEDRTIIMEDRLLGVLIPCRAFGDVQLKWSKELQRS 362
Query: 264 IGDLDLKTSGV----------------IAEPETKRIKLHHADDSFLVLTTDGINFMVNSQ 307
I + T + AEPE +L D FLVL +DG+ M++++
Sbjct: 363 ILERGFNTEALNIYQFTPPHYYTPPYLTAEPEVTYHRLR-PQDKFLVLASDGLWDMLSNE 421
Query: 308 EICDFV 313
++ V
Sbjct: 422 DVVRLV 427
>gi|171460932 protein phosphatase 1M isoform a [Homo sapiens]
Length = 298
Score = 39.3 bits (90), Expect = 0.006
Identities = 29/80 (36%), Positives = 42/80 (52%), Gaps = 7/80 (8%)
Query: 160 LTLAFLEIDKAFSSHARLSADATLLTSGTTATVALLRDGIELVVASVGDSRAILCRKGKP 219
L AF E D+ S G TA VA+ G +L +A+ GDSRAIL R+ +
Sbjct: 31 LESAFQECDEVIGRELEASGQM----GGCTALVAVSLQG-KLYMANAGDSRAILVRRDEI 85
Query: 220 MKLTIDHTPERKDEKERIKK 239
L+ + TPE E++RI++
Sbjct: 86 RPLSFEFTPE--TERQRIQQ 103
>gi|171460934 protein phosphatase 1M isoform b [Homo sapiens]
Length = 247
Score = 37.4 bits (85), Expect = 0.022
Identities = 23/53 (43%), Positives = 35/53 (66%), Gaps = 3/53 (5%)
Query: 187 GTTATVALLRDGIELVVASVGDSRAILCRKGKPMKLTIDHTPERKDEKERIKK 239
G TA VA+ G +L +A+ GDSRAIL R+ + L+ + TPE E++RI++
Sbjct: 3 GCTALVAVSLQG-KLYMANAGDSRAILVRRDEIRPLSFEFTPE--TERQRIQQ 52
>gi|65506328 protein phosphatase 1J (PP2C domain containing) [Homo
sapiens]
Length = 505
Score = 37.0 bits (84), Expect = 0.029
Identities = 72/355 (20%), Positives = 118/355 (33%), Gaps = 127/355 (35%)
Query: 122 YFAVYDGHGGPAAADFC----HTHMEKCIMDLLP-------------------------- 151
Y+ ++DGH G AA+ H H+ + + DL+
Sbjct: 153 YWGLFDGHAGGGAAEMASRLLHRHIREQLKDLVEILQDPSPPPLCLPTTPGTPDSSDPSH 212
Query: 152 -----------KEKNLETLLTLAFLEIDKAFSSHARLSADATLLTSGTTATVALLRDGIE 200
KE + E+L+ A + + G A V + G +
Sbjct: 213 LLGPQSCWSSQKEVSHESLVVGAVENAFQLMDEQMARERRGHQVEGGCCALVVIYLLG-K 271
Query: 201 LVVASVGDSRAILCRKGKPMKLTIDHTPERKDEKERIKKCGGF----------------- 243
+ VA+ GDSRAI+ R G+ + ++ + TPE E++R++ G
Sbjct: 272 VYVANAGDSRAIIVRNGEIIPMSREFTPE--TERQRLQLLGFLKPELLGSEFTHLEFPRR 329
Query: 244 VAWNSLGQ---------------------------------PHVNGRLAMTRSIGDLDLK 270
V LGQ V + +TR +GD LK
Sbjct: 330 VLPKELGQRMLYRDQNMTGWAYKKIELEDLRFPLVCGEGKKARVMATIGVTRGLGDHSLK 389
Query: 271 TSG--------VIAEPETKRIKL---HHADDSFLVLTTDGINFMVNSQEIC---DFVNQC 316
+ PE + L H D LVL TDG+ + E+ D V
Sbjct: 390 VCSSTLPIKPFLSCFPEVRVYDLTQYEHCPDDVLVLGTDGLWDVTTDCEVAATVDRVLSA 449
Query: 317 HDPNE-AAHAVTEQAI------------------QYGTEDNSTAVVVPFGAWGKY 352
++PN+ + + QA+ + G+ D+ + V+P G G Y
Sbjct: 450 YEPNDHSRYTALAQALVLGARGTPRDRGWRLPNNKLGSGDDISVFVIPLGGPGSY 504
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.134 0.403
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,377,295
Number of Sequences: 37866
Number of extensions: 653432
Number of successful extensions: 1469
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 22
Number of HSP's successfully gapped in prelim test: 13
Number of HSP's that attempted gapping in prelim test: 1381
Number of HSP's gapped (non-prelim): 49
length of query: 372
length of database: 18,247,518
effective HSP length: 104
effective length of query: 268
effective length of database: 14,309,454
effective search space: 3834933672
effective search space used: 3834933672
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.