Search of human proteins with 166706915

Search of human proteins with 166706915

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|166706915 GLIS family zinc finger 1 [Homo sapiens]
         (620 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|166706915 GLIS family zinc finger 1 [Homo sapiens]                1310   0.0  
gi|109637784 GLIS family zinc finger 3 isoform a [Homo sapiens]       397   e-110
gi|109637782 GLIS family zinc finger 3 isoform b [Homo sapiens]       397   e-110
gi|86991432 GLI-Kruppel family member GLI2 [Homo sapiens]             230   3e-60
gi|4885279 GLI family zinc finger 1 isoform 1 [Homo sapiens]          227   2e-59
gi|119393899 GLI-Kruppel family member GLI3 [Homo sapiens]            225   8e-59
gi|229892345 GLI family zinc finger 1 isoform 2 [Homo sapiens]        224   2e-58
gi|110431364 GLIS family zinc finger 2 [Homo sapiens]                 209   8e-54
gi|118766337 zinc finger protein of the cerebellum 5 [Homo sapiens]   183   5e-46
gi|22547201 zinc finger protein of the cerebellum 4 [Homo sapiens]    180   3e-45
gi|22547197 zinc finger protein of the cerebellum 2 [Homo sapiens]    176   7e-44
gi|22547182 zinc finger protein of the cerebellum 1 [Homo sapiens]    174   3e-43
gi|4507973 zinc finger protein of the cerebellum 3 [Homo sapiens]     171   2e-42
gi|133922582 zinc finger protein 358 [Homo sapiens]                   127   2e-29
gi|116014328 zinc finger protein 143 [Homo sapiens]                   125   1e-28
gi|112790163 metal-regulatory transcription factor 1 [Homo sapiens]   119   6e-27
gi|21361146 zinc finger protein 76 (expressed in testis) [Homo s...   116   5e-26
gi|38570115 zinc finger protein 362 [Homo sapiens]                    112   1e-24
gi|117956407 zinc finger protein 568 [Homo sapiens]                   109   7e-24
gi|64368880 zinc finger and SCAN domain containing 25 [Homo sapi...   109   7e-24
gi|90193619 nuclear matrix transcription factor 4 isoform c [Hom...   107   3e-23
gi|90193617 nuclear matrix transcription factor 4 isoform b [Hom...   107   3e-23
gi|90193615 nuclear matrix transcription factor 4 isoform b [Hom...   107   3e-23
gi|90193613 nuclear matrix transcription factor 4 isoform a [Hom...   107   3e-23
gi|90193611 nuclear matrix transcription factor 4 isoform a [Hom...   107   3e-23
gi|36054194 nuclear matrix transcription factor 4 isoform a [Hom...   107   3e-23
gi|13129116 zinc finger protein 426 [Homo sapiens]                    107   4e-23
gi|209180475 nuclear matrix transcription factor 4 isoform d [Ho...   106   7e-23
gi|239751768 PREDICTED: hypothetical protein XP_002347973 isofor...   106   7e-23
gi|239751766 PREDICTED: hypothetical protein XP_002347974 isofor...   106   7e-23

>gi|166706915 GLIS family zinc finger 1 [Homo sapiens]
          Length = 620

 Score = 1310 bits (3391), Expect = 0.0
 Identities = 620/620 (100%), Positives = 620/620 (100%)

Query: 1   MAEARTSLSAHCRGPLATGLHPDLDLPGRSLATPAPSCYLLGSEPSSGLGLQPETHLPEG 60
           MAEARTSLSAHCRGPLATGLHPDLDLPGRSLATPAPSCYLLGSEPSSGLGLQPETHLPEG
Sbjct: 1   MAEARTSLSAHCRGPLATGLHPDLDLPGRSLATPAPSCYLLGSEPSSGLGLQPETHLPEG 60

Query: 61  SLKRCCVLGLPPTSPASSSPCASSDVTSIIRSSQTSLVTCVNGLRSPPLTGDLGGPSKRA 120
           SLKRCCVLGLPPTSPASSSPCASSDVTSIIRSSQTSLVTCVNGLRSPPLTGDLGGPSKRA
Sbjct: 61  SLKRCCVLGLPPTSPASSSPCASSDVTSIIRSSQTSLVTCVNGLRSPPLTGDLGGPSKRA 120

Query: 121 RPGPASTDSHEGSLQLEACRKASFLKQEPADEFSELFGPHQQGLPPPYPLSQLPPGPSLG 180
           RPGPASTDSHEGSLQLEACRKASFLKQEPADEFSELFGPHQQGLPPPYPLSQLPPGPSLG
Sbjct: 121 RPGPASTDSHEGSLQLEACRKASFLKQEPADEFSELFGPHQQGLPPPYPLSQLPPGPSLG 180

Query: 181 GLGLGLAGRVVAGRQACRWVDCCAAYEQQEELVRHIEKSHIDQRKGEDFTCFWAGCVRRY 240
           GLGLGLAGRVVAGRQACRWVDCCAAYEQQEELVRHIEKSHIDQRKGEDFTCFWAGCVRRY
Sbjct: 181 GLGLGLAGRVVAGRQACRWVDCCAAYEQQEELVRHIEKSHIDQRKGEDFTCFWAGCVRRY 240

Query: 241 KPFNARYKLLIHMRVHSGEKPNKCMFEGCSKAFSRLENLKIHLRSHTGEKPYLCQHPGCQ 300
           KPFNARYKLLIHMRVHSGEKPNKCMFEGCSKAFSRLENLKIHLRSHTGEKPYLCQHPGCQ
Sbjct: 241 KPFNARYKLLIHMRVHSGEKPNKCMFEGCSKAFSRLENLKIHLRSHTGEKPYLCQHPGCQ 300

Query: 301 KAFSNSSDRAKHQRTHLDTKPYACQIPGCSKRYTDPSSLRKHVKAHSAKEQQVRKKLHAG 360
           KAFSNSSDRAKHQRTHLDTKPYACQIPGCSKRYTDPSSLRKHVKAHSAKEQQVRKKLHAG
Sbjct: 301 KAFSNSSDRAKHQRTHLDTKPYACQIPGCSKRYTDPSSLRKHVKAHSAKEQQVRKKLHAG 360

Query: 361 PDTEADVLTECLVLQQLHTSTQLAASDGKGGCGLGQELLPGVYPGSITPHNGLASGLLPP 420
           PDTEADVLTECLVLQQLHTSTQLAASDGKGGCGLGQELLPGVYPGSITPHNGLASGLLPP
Sbjct: 361 PDTEADVLTECLVLQQLHTSTQLAASDGKGGCGLGQELLPGVYPGSITPHNGLASGLLPP 420

Query: 421 AHDVPSRHHPLDATTSSHHHLSPLPMAESTRDGLGPGLLSPIVSPLKGLGPPPLPPSSQS 480
           AHDVPSRHHPLDATTSSHHHLSPLPMAESTRDGLGPGLLSPIVSPLKGLGPPPLPPSSQS
Sbjct: 421 AHDVPSRHHPLDATTSSHHHLSPLPMAESTRDGLGPGLLSPIVSPLKGLGPPPLPPSSQS 480

Query: 481 HSPGGQPFPTLPSKPSYPPFQSPPPPPLPSPQGYQGSFHSIQSCFPYGDCYRMAEPAAGG 540
           HSPGGQPFPTLPSKPSYPPFQSPPPPPLPSPQGYQGSFHSIQSCFPYGDCYRMAEPAAGG
Sbjct: 481 HSPGGQPFPTLPSKPSYPPFQSPPPPPLPSPQGYQGSFHSIQSCFPYGDCYRMAEPAAGG 540

Query: 541 DGLVGETHGFNPLRPNGYHSLSTPLPATGYEALAEASCPTALPQQPSEDVVSSGPEDCGF 600
           DGLVGETHGFNPLRPNGYHSLSTPLPATGYEALAEASCPTALPQQPSEDVVSSGPEDCGF
Sbjct: 541 DGLVGETHGFNPLRPNGYHSLSTPLPATGYEALAEASCPTALPQQPSEDVVSSGPEDCGF 600

Query: 601 FPNGAFDHCLGHIPSIYTDT 620
           FPNGAFDHCLGHIPSIYTDT
Sbjct: 601 FPNGAFDHCLGHIPSIYTDT 620


>gi|109637784 GLIS family zinc finger 3 isoform a [Homo sapiens]
          Length = 930

 Score =  397 bits (1020), Expect = e-110
 Identities = 282/703 (40%), Positives = 336/703 (47%), Gaps = 130/703 (18%)

Query: 20  LHPDLDLPGRSLATPAPSCYLLGSEPSSGLGLQPETHLPEGSLKRCCVLGLPPTSPASSS 79
           L P   +   S++   PS YL G+E S      P          R     L   SP S  
Sbjct: 254 LPPGTSMSSNSVSNSLPS-YLFGTESSHSPYPSPRHSSTRSHSARSKKRALS-LSPLSDG 311

Query: 80  PCASSDVTSIIRSSQTSLVTCVNGLRSPPLT------------GDLGGPSKRARPGPAST 127
                D  +IIR+S TSLV  +NG R+ P              G  G    + RP P S 
Sbjct: 312 --IGIDFNTIIRTSPTSLVAYINGSRASPANLSPQPEVYGHFLGVRGSCIPQPRPVPGSQ 369

Query: 128 DS---HEGSLQLEACRKASFLKQEPADEFSE----------------LFGPHQQG----- 163
                  G L L A  +   L+ E   +                   L GP  Q      
Sbjct: 370 KGVLVAPGGLALPAYGEDGALEHERMQQLEHGGLQPGLVNHMVVQHGLPGPDSQSAGLFK 429

Query: 164 -------------LPPPYPLSQLPP-------------------GPSLGGLGLGLA---- 187
                        LPP  PL  LPP                   GP    L L  A    
Sbjct: 430 TERLEEFPGSTVDLPPAPPLPPLPPPPGPPPPYHAHAHLHHPELGPHAQQLALPQATLDD 489

Query: 188 -GRV--VAGRQACRWVDCCAAYEQQEELVRHIEKSHIDQRKGEDFTCFWAGCVRRYKPFN 244
            G +  + G+  CRW+DC A Y+QQEELVRHIEK HIDQRKGEDFTCFWAGC RRYKPFN
Sbjct: 490 DGEMDGIGGKHCCRWIDCSALYDQQEELVRHIEKVHIDQRKGEDFTCFWAGCPRRYKPFN 549

Query: 245 ARYKLLIHMRVHSGEKPNKCMFEGCSKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFS 304
           ARYKLLIHMRVHSGEKPNKC FEGC KAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFS
Sbjct: 550 ARYKLLIHMRVHSGEKPNKCTFEGCEKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFS 609

Query: 305 NSSDRAKHQRTHLDTKPYACQIPGCSKRYTDPSSLRKHVKAHSAKEQQVRKKLHAGPDTE 364
           NSSDRAKHQRTHLDTKPYACQIPGC+KRYTDPSSLRKHVKAHS+KEQQ RKKL +  +  
Sbjct: 610 NSSDRAKHQRTHLDTKPYACQIPGCTKRYTDPSSLRKHVKAHSSKEQQARKKLRSSTELH 669

Query: 365 ADVLTECLVLQQLH--TSTQLAASDGKGG--CGLGQELLPG-VYPGSITPHNGLASGLLP 419
            D+LT+CL +Q L   TS + AA++G  G   G G +L    ++  + +  +G A+G +P
Sbjct: 670 PDLLTDCLTVQSLQPATSPRDAAAEGTVGRSPGPGPDLYSAPIFSSNYSSRSGTAAGAVP 729

Query: 420 PAHDV--PSRHHPLDATT-SSHHHLSPLPMAESTRDGLGPGLLSP-IVSP---------L 466
           P H V  PS  H +  +  +    L PL   ++  +   P   SP  +SP         L
Sbjct: 730 PPHPVSHPSPGHNVQGSPHNPSSQLPPLTAVDAGAERFAPSAPSPHHISPRRVPAPSSIL 789

Query: 467 KGLGPPPLPPSSQSHSPGGQPFPTLPSKPS-------YPPFQSPPPPPLPSPQGYQGSFH 519
           +   PP     S SH    QP      +P+       Y   Q   PP  P  Q       
Sbjct: 790 QRTQPPYTQQPSGSHLKSYQPETNSSFQPNGIHVHGFYGQLQKFCPPHYPDSQRIVPPVS 849

Query: 520 SIQSCFPYGDCYRMAEPAAGGDGLVGETHGFNPLRPNGYHSLSTPLPATGYEALAEASCP 579
           S      + DC     P + G       H           + ST    T Y+        
Sbjct: 850 SCSVVPSFEDC---LVPTSMGQASFDVFH----------RAFSTHSGITVYD-------- 888

Query: 580 TALPQQPSE---DVVSSGPEDCGFFPNGAFDHCLGHIPSIYTD 619
             LP   S    + + SG ED  F      D C   + S+YT+
Sbjct: 889 --LPSSSSSLFGESLRSGAEDATFLQISTVDRCPSQLSSVYTE 929


>gi|109637782 GLIS family zinc finger 3 isoform b [Homo sapiens]
          Length = 775

 Score =  397 bits (1020), Expect = e-110
 Identities = 282/703 (40%), Positives = 336/703 (47%), Gaps = 130/703 (18%)

Query: 20  LHPDLDLPGRSLATPAPSCYLLGSEPSSGLGLQPETHLPEGSLKRCCVLGLPPTSPASSS 79
           L P   +   S++   PS YL G+E S      P          R     L   SP S  
Sbjct: 99  LPPGTSMSSNSVSNSLPS-YLFGTESSHSPYPSPRHSSTRSHSARSKKRALS-LSPLSDG 156

Query: 80  PCASSDVTSIIRSSQTSLVTCVNGLRSPPLT------------GDLGGPSKRARPGPAST 127
                D  +IIR+S TSLV  +NG R+ P              G  G    + RP P S 
Sbjct: 157 --IGIDFNTIIRTSPTSLVAYINGSRASPANLSPQPEVYGHFLGVRGSCIPQPRPVPGSQ 214

Query: 128 DS---HEGSLQLEACRKASFLKQEPADEFSE----------------LFGPHQQG----- 163
                  G L L A  +   L+ E   +                   L GP  Q      
Sbjct: 215 KGVLVAPGGLALPAYGEDGALEHERMQQLEHGGLQPGLVNHMVVQHGLPGPDSQSAGLFK 274

Query: 164 -------------LPPPYPLSQLPP-------------------GPSLGGLGLGLA---- 187
                        LPP  PL  LPP                   GP    L L  A    
Sbjct: 275 TERLEEFPGSTVDLPPAPPLPPLPPPPGPPPPYHAHAHLHHPELGPHAQQLALPQATLDD 334

Query: 188 -GRV--VAGRQACRWVDCCAAYEQQEELVRHIEKSHIDQRKGEDFTCFWAGCVRRYKPFN 244
            G +  + G+  CRW+DC A Y+QQEELVRHIEK HIDQRKGEDFTCFWAGC RRYKPFN
Sbjct: 335 DGEMDGIGGKHCCRWIDCSALYDQQEELVRHIEKVHIDQRKGEDFTCFWAGCPRRYKPFN 394

Query: 245 ARYKLLIHMRVHSGEKPNKCMFEGCSKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFS 304
           ARYKLLIHMRVHSGEKPNKC FEGC KAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFS
Sbjct: 395 ARYKLLIHMRVHSGEKPNKCTFEGCEKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFS 454

Query: 305 NSSDRAKHQRTHLDTKPYACQIPGCSKRYTDPSSLRKHVKAHSAKEQQVRKKLHAGPDTE 364
           NSSDRAKHQRTHLDTKPYACQIPGC+KRYTDPSSLRKHVKAHS+KEQQ RKKL +  +  
Sbjct: 455 NSSDRAKHQRTHLDTKPYACQIPGCTKRYTDPSSLRKHVKAHSSKEQQARKKLRSSTELH 514

Query: 365 ADVLTECLVLQQLH--TSTQLAASDGKGG--CGLGQELLPG-VYPGSITPHNGLASGLLP 419
            D+LT+CL +Q L   TS + AA++G  G   G G +L    ++  + +  +G A+G +P
Sbjct: 515 PDLLTDCLTVQSLQPATSPRDAAAEGTVGRSPGPGPDLYSAPIFSSNYSSRSGTAAGAVP 574

Query: 420 PAHDV--PSRHHPLDATT-SSHHHLSPLPMAESTRDGLGPGLLSP-IVSP---------L 466
           P H V  PS  H +  +  +    L PL   ++  +   P   SP  +SP         L
Sbjct: 575 PPHPVSHPSPGHNVQGSPHNPSSQLPPLTAVDAGAERFAPSAPSPHHISPRRVPAPSSIL 634

Query: 467 KGLGPPPLPPSSQSHSPGGQPFPTLPSKPS-------YPPFQSPPPPPLPSPQGYQGSFH 519
           +   PP     S SH    QP      +P+       Y   Q   PP  P  Q       
Sbjct: 635 QRTQPPYTQQPSGSHLKSYQPETNSSFQPNGIHVHGFYGQLQKFCPPHYPDSQRIVPPVS 694

Query: 520 SIQSCFPYGDCYRMAEPAAGGDGLVGETHGFNPLRPNGYHSLSTPLPATGYEALAEASCP 579
           S      + DC     P + G       H           + ST    T Y+        
Sbjct: 695 SCSVVPSFEDC---LVPTSMGQASFDVFH----------RAFSTHSGITVYD-------- 733

Query: 580 TALPQQPSE---DVVSSGPEDCGFFPNGAFDHCLGHIPSIYTD 619
             LP   S    + + SG ED  F      D C   + S+YT+
Sbjct: 734 --LPSSSSSLFGESLRSGAEDATFLQISTVDRCPSQLSSVYTE 774


>gi|86991432 GLI-Kruppel family member GLI2 [Homo sapiens]
          Length = 1586

 Score =  230 bits (587), Expect = 3e-60
 Identities = 150/363 (41%), Positives = 181/363 (49%), Gaps = 68/363 (18%)

Query: 190 VVAGRQACRWVDCCAAYEQQEELVRHIEKSHIDQRKGEDFTCFWAGCVRRYKPFNARYKL 249
           VV     C W DC   Y+ QE+LV HI   HI   K E F C W  C R  KPF A+Y L
Sbjct: 432 VVIYETNCHWEDCTKEYDTQEQLVHHINNEHIHGEKKE-FVCRWQACTREQKPFKAQYML 490

Query: 250 LIHMRVHSGEKPNKCMFEGCSKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDR 309
           ++HMR H+GEKP+KC FEGCSKA+SRLENLK HLRSHTGEKPY+C+H GC KAFSN+SDR
Sbjct: 491 VVHMRRHTGEKPHKCTFEGCSKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDR 550

Query: 310 AKHQ-RTHLDTKPYACQIPGCSKRYTDPSSLRKHVK------AHSAKEQQVRKKLH---- 358
           AKHQ RTH + KPY C+IPGC+KRYTDPSSLRKHVK      AH  K+Q  R  +H    
Sbjct: 551 AKHQNRTHSNEKPYICKIPGCTKRYTDPSSLRKHVKTVHGPDAHVTKKQ--RNDVHLRTP 608

Query: 359 --------------AGPD-TEA----DVLTECLVLQQLHTSTQLAASDGKG---GCG--- 393
                          GP+ TEA      + +CL ++ + T +        G    C    
Sbjct: 609 LLKENGDSEAGTEPGGPESTEASSTSQAVEDCLHVRAIKTESSGLCQSSPGAQSSCSSEP 668

Query: 394 --LGQE-------LLPGVYPGSITPHNGLASGLLPPAHDVPSRHHPLDATTSSHHHLSPL 444
             LG          +PG  PGS+     L     PP  D  +   P         H++ +
Sbjct: 669 SPLGSAPNNDSGVEMPGTGPGSLGDLTALDD--TPPGADTSALAAPSAGGLQLRKHMTTM 726

Query: 445 PMAESTRDGLGPGLLSPIVSPLKGLGP---------PPLPPSSQ-----SHSPGGQPFPT 490
              E     L    L  +       GP         PPLP S       S S GG P   
Sbjct: 727 HRFEQ----LKKEKLKSLKDSCSWAGPTPHTRNTKLPPLPGSGSILENFSGSGGGGPAGL 782

Query: 491 LPS 493
           LP+
Sbjct: 783 LPN 785



 Score = 30.8 bits (68), Expect = 3.9
 Identities = 30/121 (24%), Positives = 46/121 (38%), Gaps = 22/121 (18%)

Query: 380  STQLAASDGKGGCGLGQELLPGVYPGSITPHNG------LASGLL---PPAHDVPSRHH- 429
            S  LAAS  + G      LLP   PG + P  G         GL+   PP    P+  H 
Sbjct: 1325 SHHLAASMSQEGYHQVPSLLPARQPGFMEPQTGPMGVATAGFGLVQPRPPLEPSPTGRHR 1384

Query: 430  -------PLDATTSSHHHLSPLPMAESTRDGLGPGLLSPIVSPLKGLGPPPLPPSSQSHS 482
                    L    ++ H ++ +P ++ T + +  G +  +     G  PP  PP     +
Sbjct: 1385 GVRAVQQQLAYARATGHAMAAMPSSQETAEAVPKGAMGNM-----GSVPPQPPPQDAGGA 1439

Query: 483  P 483
            P
Sbjct: 1440 P 1440



 Score = 30.4 bits (67), Expect = 5.1
 Identities = 36/141 (25%), Positives = 49/141 (34%), Gaps = 13/141 (9%)

Query: 108 PLTGDLGGPSKRARPG-PASTDSHEGSLQLEACRKASFLKQEPADEFSELFGPHQQGLPP 166
           PL  + G       PG P ST++   S  +E C     +K E +       G        
Sbjct: 608 PLLKENGDSEAGTEPGGPESTEASSTSQAVEDCLHVRAIKTESSGLCQSSPGAQSSCSSE 667

Query: 167 PYPLSQLP---PGPSLGGLGLGLAGRVVAGRQACRWVDCCAAYEQQE---ELVRHIEKSH 220
           P PL   P    G  + G G G  G + A        D  A         +L +H+   H
Sbjct: 668 PSPLGSAPNNDSGVEMPGTGPGSLGDLTALDDTPPGADTSALAAPSAGGLQLRKHMTTMH 727

Query: 221 -IDQRKGEDF-----TCFWAG 235
             +Q K E       +C WAG
Sbjct: 728 RFEQLKKEKLKSLKDSCSWAG 748


>gi|4885279 GLI family zinc finger 1 isoform 1 [Homo sapiens]
          Length = 1106

 Score =  227 bits (579), Expect = 2e-59
 Identities = 132/317 (41%), Positives = 177/317 (55%), Gaps = 46/317 (14%)

Query: 82  ASSDVTSIIRSSQTSLVTCVNGLRSPP-----------LTGDLGGPSK-RARPGPAST-- 127
           AS D+ ++IR+S +SLV  +N   + P           ++  LG P++   + GP+ +  
Sbjct: 91  ASLDLQTVIRTSPSSLVAFINSRCTSPGGSYGHLSIGTMSPSLGFPAQMNHQKGPSPSFG 150

Query: 128 -------DSHEGSLQLEACRKASFLKQEPADEFSELFGPHQQGLPPPYPLSQLPPGPSLG 180
                  DS  G +      +  F   +   E   L G  ++      PL      P+  
Sbjct: 151 VQPCGPHDSARGGMIPHPQSRGPFPTCQLKSELDMLVGKCREE-----PLEGDMSSPNST 205

Query: 181 GLGLGLAGRVVAGRQA----------------CRWVDCCAAYEQQEELVRHIEKSHIDQR 224
           G+   L G ++ GR+                 CRW  C   ++ QE+LV HI   HI   
Sbjct: 206 GIQDPLLG-MLDGREDLEREEKREPESVYETDCRWDGCSQEFDSQEQLVHHINSEHIHGE 264

Query: 225 KGEDFTCFWAGCVRRYKPFNARYKLLIHMRVHSGEKPNKCMFEGCSKAFSRLENLKIHLR 284
           + E F C W GC R  +PF A+Y L++HMR H+GEKP+KC FEGC K++SRLENLK HLR
Sbjct: 265 RKE-FVCHWGGCSRELRPFKAQYMLVVHMRRHTGEKPHKCTFEGCRKSYSRLENLKTHLR 323

Query: 285 SHTGEKPYLCQHPGCQKAFSNSSDRAKHQ-RTHLDTKPYACQIPGCSKRYTDPSSLRKHV 343
           SHTGEKPY+C+H GC KAFSN+SDRAKHQ RTH + KPY C++PGC+KRYTDPSSLRKHV
Sbjct: 324 SHTGEKPYMCEHEGCSKAFSNASDRAKHQNRTHSNEKPYVCKLPGCTKRYTDPSSLRKHV 383

Query: 344 KAHSAKEQQVRKKLHAG 360
           K     +  V K+ H G
Sbjct: 384 KTVHGPDAHVTKR-HRG 399


>gi|119393899 GLI-Kruppel family member GLI3 [Homo sapiens]
          Length = 1580

 Score =  225 bits (574), Expect = 8e-59
 Identities = 106/175 (60%), Positives = 123/175 (70%), Gaps = 6/175 (3%)

Query: 197 CRWVDCCAAYEQQEELVRHIEKSHIDQRKGEDFTCFWAGCVRRYKPFNARYKLLIHMRVH 256
           C W  C   ++ QE+LV HI   HI   K E F C W  C R  KPF A+Y L++HMR H
Sbjct: 482 CHWEGCAREFDTQEQLVHHINNDHIHGEKKE-FVCRWLDCSREQKPFKAQYMLVVHMRRH 540

Query: 257 SGEKPNKCMFEGCSKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDRAKHQ-RT 315
           +GEKP+KC FEGC+KA+SRLENLK HLRSHTGEKPY+C+H GC KAFSN+SDRAKHQ RT
Sbjct: 541 TGEKPHKCTFEGCTKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRT 600

Query: 316 HLDTKPYACQIPGCSKRYTDPSSLRKHVKAHSAKEQQVRKK----LHAGPDTEAD 366
           H + KPY C+IPGC+KRYTDPSSLRKHVK     E  V KK    +H  P    D
Sbjct: 601 HSNEKPYVCKIPGCTKRYTDPSSLRKHVKTVHGPEAHVTKKQRGDIHPRPPPPRD 655


>gi|229892345 GLI family zinc finger 1 isoform 2 [Homo sapiens]
          Length = 978

 Score =  224 bits (570), Expect = 2e-58
 Identities = 101/165 (61%), Positives = 122/165 (73%), Gaps = 3/165 (1%)

Query: 197 CRWVDCCAAYEQQEELVRHIEKSHIDQRKGEDFTCFWAGCVRRYKPFNARYKLLIHMRVH 256
           CRW  C   ++ QE+LV HI   HI   + E F C W GC R  +PF A+Y L++HMR H
Sbjct: 109 CRWDGCSQEFDSQEQLVHHINSEHIHGERKE-FVCHWGGCSRELRPFKAQYMLVVHMRRH 167

Query: 257 SGEKPNKCMFEGCSKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDRAKHQ-RT 315
           +GEKP+KC FEGC K++SRLENLK HLRSHTGEKPY+C+H GC KAFSN+SDRAKHQ RT
Sbjct: 168 TGEKPHKCTFEGCRKSYSRLENLKTHLRSHTGEKPYMCEHEGCSKAFSNASDRAKHQNRT 227

Query: 316 HLDTKPYACQIPGCSKRYTDPSSLRKHVKAHSAKEQQVRKKLHAG 360
           H + KPY C++PGC+KRYTDPSSLRKHVK     +  V K+ H G
Sbjct: 228 HSNEKPYVCKLPGCTKRYTDPSSLRKHVKTVHGPDAHVTKR-HRG 271


>gi|110431364 GLIS family zinc finger 2 [Homo sapiens]
          Length = 524

 Score =  209 bits (531), Expect = 8e-54
 Identities = 146/393 (37%), Positives = 178/393 (45%), Gaps = 81/393 (20%)

Query: 197 CRWVDCCAAYEQQEELVRHIEKSHIDQRKGEDFTCFWAGCVRRYKPFNARYKLLIHMRVH 256
           CRW  C   +E  ++LV H+   H+   K   + C W GC R  + FNARYK+LIH+R H
Sbjct: 170 CRWAKCNQLFELLQDLVDHVNDYHVKPEKDAGYCCHWEGCARHGRGFNARYKMLIHIRTH 229

Query: 257 SGEKPNKCMFEGCSKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDRAKHQRTH 316
           + EKP++C    CSK+FSRLENLKIH RSHTGEKPY+C + GC K +SNSSDR KH RTH
Sbjct: 230 TNEKPHRC--PTCSKSFSRLENLKIHNRSHTGEKPYVCPYEGCNKRYSNSSDRFKHTRTH 287

Query: 317 LDTKPYACQIPGCSKRYTDPSSLRKHVKAHS---AKEQQVRKKLHAGPDTEADVLTECLV 373
              KPY C++PGC KRYTDPSSLRKH+KAH    + EQQ   +L   P            
Sbjct: 288 YVDKPYYCKMPGCHKRYTDPSSLRKHIKAHGHFVSHEQQELLQLRPPP------------ 335

Query: 374 LQQLHTSTQLAASDGKGGCGLGQELLPGVYPGSITPHNGLASGLLPPAHDVPSRHHPLDA 433
                    L A DG       Q ++P   P ++    GL      P   +P    PLD 
Sbjct: 336 ------KPPLPAPDGGPYVSGAQIIIPN--PAALFGGPGL------PGLPLPLAPGPLD- 380

Query: 434 TTSSHHHLSPLPMAESTRDGLGPGLLSPIVSPLKGLGPPPLPPSSQSHSPGGQPFPTLPS 493
                  LS L        G G            G+GP             G P P LP 
Sbjct: 381 -------LSALACGNGGGSGGG-----------GGMGP-------------GLPGPVLPL 409

Query: 494 KPSYPPFQSPPPPPLPSPQGYQGSFHSIQSCFPYGDCYRMAEPAAGGDGLVGETHGFNPL 553
             +  P        LPSP G  G    + S         +   AAGG     +  G  P 
Sbjct: 410 NLAKNPL-------LPSPFGAGGLGLPVVS---------LLAGAAGGKAEGEKGRGSVPT 453

Query: 554 RPNGYHSLSTPLPATGYEALAEASCPTALPQQP 586
           R  G     TPL  T  E+      P  LP  P
Sbjct: 454 RALGMEGHKTPLERT--ESSCSRPSPDGLPLLP 484


>gi|118766337 zinc finger protein of the cerebellum 5 [Homo sapiens]
          Length = 663

 Score =  183 bits (464), Expect = 5e-46
 Identities = 88/184 (47%), Positives = 105/184 (57%), Gaps = 16/184 (8%)

Query: 163 GLPPPYPLSQLPPGPSLGGLGLGLAGRVVAGRQACRWVDCCAAYEQQEELVRHIEKSHID 222
           GLPPP P    PP P   G           G + C        +    ELV H+   H+ 
Sbjct: 408 GLPPPPPPPPPPPPPPPAG-----------GAKPCS-----KTFGTMHELVNHVTVEHVG 451

Query: 223 QRKGEDFTCFWAGCVRRYKPFNARYKLLIHMRVHSGEKPNKCMFEGCSKAFSRLENLKIH 282
             +     CFW  C R  KPF A+YKL+ H+RVH+GEKP  C F GC K F+R ENLKIH
Sbjct: 452 GPEQSSHVCFWEDCPREGKPFKAKYKLINHIRVHTGEKPFPCPFPGCGKVFARSENLKIH 511

Query: 283 LRSHTGEKPYLCQHPGCQKAFSNSSDRAKHQRTHLDTKPYACQIPGCSKRYTDPSSLRKH 342
            R+HTGEKP+ C+  GC + F+NSSDR KH   H   KPY C+I GC K YT PSSLRKH
Sbjct: 512 KRTHTGEKPFKCEFDGCDRKFANSSDRKKHSHVHTSDKPYYCKIRGCDKSYTHPSSLRKH 571

Query: 343 VKAH 346
           +K H
Sbjct: 572 MKIH 575



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 25/89 (28%), Positives = 38/89 (42%), Gaps = 7/89 (7%)

Query: 269 CSKAFSRLENLKIHLR-SHTG---EKPYLCQHPGCQ---KAFSNSSDRAKHQRTHLDTKP 321
           CSK F  +  L  H+   H G   +  ++C    C    K F        H R H   KP
Sbjct: 431 CSKTFGTMHELVNHVTVEHVGGPEQSSHVCFWEDCPREGKPFKAKYKLINHIRVHTGEKP 490

Query: 322 YACQIPGCSKRYTDPSSLRKHVKAHSAKE 350
           + C  PGC K +    +L+ H + H+ ++
Sbjct: 491 FPCPFPGCGKVFARSENLKIHKRTHTGEK 519



 Score = 38.9 bits (89), Expect = 0.014
 Identities = 30/113 (26%), Positives = 39/113 (34%), Gaps = 15/113 (13%)

Query: 482 SPGGQPFPTLPSKPSYPPFQSPPPPPLPSPQGYQGSFHSIQSCFPYGDCYRMAEPAAGGD 541
           S G QP    P  P  PP  SPPPPP P P      + +  S               GG 
Sbjct: 142 SSGAQPSAPPPPAPPLPPTPSPPPPPPPPPPPALSGYTTTNS---------------GGG 186

Query: 542 GLVGETHGFNPLRPNGYHSLSTPLPATGYEALAEASCPTALPQQPSEDVVSSG 594
           G  G+ H  + +      + +      G     E    T  PQ P+    S+G
Sbjct: 187 GSSGKGHSRDFVLRRDLSATAPAAAMHGAPLGGEQRSGTGSPQHPAPPPHSAG 239



 Score = 38.5 bits (88), Expect = 0.019
 Identities = 40/118 (33%), Positives = 45/118 (38%), Gaps = 26/118 (22%)

Query: 400 PGVYPGSITP-HNGLAS--GLLPPAHDVPSRHHPLDATTSSHHHLSPLPMAESTRDGLGP 456
           PGV    + P H   AS  GL PP+   P+ H    A  +    L   P A S   G G 
Sbjct: 84  PGVATTPLGPEHMAQASTLGLSPPSQAFPA-HPEAPAAAARAAALVAHPGAGSYPCGGGS 142

Query: 457 GLLSPIVSPLKGLGPPPLPPSSQSHSPGGQPFPTLPSKPSYPPFQSPPPPPLPSPQGY 514
               P   P      PP PP              LP  PS PP   PPPPP P+  GY
Sbjct: 143 SGAQPSAPP------PPAPP--------------LPPTPSPPP--PPPPPPPPALSGY 178



 Score = 32.0 bits (71), Expect = 1.7
 Identities = 40/151 (26%), Positives = 53/151 (35%), Gaps = 24/151 (15%)

Query: 377 LHTSTQLAASDGKGGCGLGQEL--LPGVYPGSITPHNG-----LASGLLPPAHDVPSRHH 429
           +  S   A  DG GG  L   L   PG   G   P NG     LA+     A ++  R  
Sbjct: 242 ISASGTYAGPDGSGGPALFPALHDTPGAPGGHPHPLNGQMRLGLAAAAAAAAAELYGRAE 301

Query: 430 PLDATTSSHHHLSPLPMAESTR-DGLGPGLLSPIVSPLKGLGPPPLPPSSQSHSPGGQPF 488
           P  A  S   H   +  A +    G G   L+  ++           P  Q H+P     
Sbjct: 302 PPFAPRSGDAHYGAVAAAAAAALHGYGAVNLNLNLAAAAAAAAAGPGPHLQHHAP----- 356

Query: 489 PTLPSKPSYPPFQSPPPPPLPSPQGYQGSFH 519
                    PP  +PPPPP P+   +Q   H
Sbjct: 357 ---------PP--APPPPPAPAQHPHQHHPH 376


>gi|22547201 zinc finger protein of the cerebellum 4 [Homo sapiens]
          Length = 334

 Score =  180 bits (457), Expect = 3e-45
 Identities = 85/198 (42%), Positives = 112/198 (56%), Gaps = 9/198 (4%)

Query: 197 CRWVD---------CCAAYEQQEELVRHIEKSHIDQRKGEDFTCFWAGCVRRYKPFNARY 247
           C+W+          C   +    ELV H+   H+   +  +  CFW  C R+ KPF A+Y
Sbjct: 130 CKWLAADGTATPSLCSKTFSTMHELVTHVTVEHVGGPEQANHICFWEECPRQGKPFKAKY 189

Query: 248 KLLIHMRVHSGEKPNKCMFEGCSKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSS 307
           KL+ H+RVH+GEKP  C F GC K F+R ENLKIH R+HTGEKP+ C+  GC++ F+NSS
Sbjct: 190 KLVNHIRVHTGEKPFPCPFPGCGKVFARSENLKIHKRTHTGEKPFRCEFEGCERRFANSS 249

Query: 308 DRAKHQRTHLDTKPYACQIPGCSKRYTDPSSLRKHVKAHSAKEQQVRKKLHAGPDTEADV 367
           DR KH   H   KPY C++ GC K YT PSSLRKH+K H            A P      
Sbjct: 250 DRKKHSHVHTSDKPYTCKVRGCDKCYTHPSSLRKHMKVHGRSPPPSSGYDSATPSALVSP 309

Query: 368 LTECLVLQQLHTSTQLAA 385
            ++C    Q+ +S  +AA
Sbjct: 310 SSDCGHKSQVASSAAVAA 327


>gi|22547197 zinc finger protein of the cerebellum 2 [Homo sapiens]
          Length = 532

 Score =  176 bits (445), Expect = 7e-44
 Identities = 79/165 (47%), Positives = 100/165 (60%), Gaps = 12/165 (7%)

Query: 197 CRWVD----------CCAAYEQQEELVRHIEKSHIDQRKGEDFTCFWAGCVRRYKPFNAR 246
           C+W+D          C   +    ELV H+   H+   +  +  CFW  C R  KPF A+
Sbjct: 258 CKWIDPEQLSNPKKSCNKTFSTMHELVTHVSVEHVGGPEQSNHVCFWEECPREGKPFKAK 317

Query: 247 YKLLIHMRVHSGEKPNKCMFEGCSKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNS 306
           YKL+ H+RVH+GEKP  C F GC K F+R ENLKIH R+HTGEKP+ C+  GC + F+NS
Sbjct: 318 YKLVNHIRVHTGEKPFPCPFPGCGKVFARSENLKIHKRTHTGEKPFQCEFEGCDRRFANS 377

Query: 307 SDRAKHQRTHLDTKPYACQIPGCSKRYTDPSSLRKHVKAHSAKEQ 351
           SDR KH   H   KPY C++  C K YT PSSLRKH+K H +  Q
Sbjct: 378 SDRKKHMHVHTSDKPYLCKM--CDKSYTHPSSLRKHMKVHESSPQ 420


>gi|22547182 zinc finger protein of the cerebellum 1 [Homo sapiens]
          Length = 447

 Score =  174 bits (440), Expect = 3e-43
 Identities = 78/165 (47%), Positives = 100/165 (60%), Gaps = 12/165 (7%)

Query: 197 CRWVD----------CCAAYEQQEELVRHIEKSHIDQRKGEDFTCFWAGCVRRYKPFNAR 246
           C+W++          C   +    ELV H+   H+   +  +  CFW  C R  KPF A+
Sbjct: 227 CKWIEPEQLANPKKSCNKTFSTMHELVTHVTVEHVGGPEQSNHICFWEECPREGKPFKAK 286

Query: 247 YKLLIHMRVHSGEKPNKCMFEGCSKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNS 306
           YKL+ H+RVH+GEKP  C F GC K F+R ENLKIH R+HTGEKP+ C+  GC + F+NS
Sbjct: 287 YKLVNHIRVHTGEKPFPCPFPGCGKVFARSENLKIHKRTHTGEKPFKCEFEGCDRRFANS 346

Query: 307 SDRAKHQRTHLDTKPYACQIPGCSKRYTDPSSLRKHVKAHSAKEQ 351
           SDR KH   H   KPY C++  C K YT PSSLRKH+K H +  Q
Sbjct: 347 SDRKKHMHVHTSDKPYLCKM--CDKSYTHPSSLRKHMKVHESSSQ 389


>gi|4507973 zinc finger protein of the cerebellum 3 [Homo sapiens]
          Length = 467

 Score =  171 bits (433), Expect = 2e-42
 Identities = 76/164 (46%), Positives = 100/164 (60%), Gaps = 12/164 (7%)

Query: 196 ACRWVD----------CCAAYEQQEELVRHIEKSHIDQRKGEDFTCFWAGCVRRYKPFNA 245
           +C+W+D          C   +    ELV H+   H+   +  +  C+W  C R  K F A
Sbjct: 252 SCKWIDEAQLSRPKKSCDRTFSTMHELVTHVTMEHVGGPEQNNHVCYWEECPREGKSFKA 311

Query: 246 RYKLLIHMRVHSGEKPNKCMFEGCSKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSN 305
           +YKL+ H+RVH+GEKP  C F GC K F+R ENLKIH R+HTGEKP+ C+  GC + F+N
Sbjct: 312 KYKLVNHIRVHTGEKPFPCPFPGCGKIFARSENLKIHKRTHTGEKPFKCEFEGCDRRFAN 371

Query: 306 SSDRAKHQRTHLDTKPYACQIPGCSKRYTDPSSLRKHVKAHSAK 349
           SSDR KH   H   KPY C++  C K YT PSSLRKH+K H ++
Sbjct: 372 SSDRKKHMHVHTSDKPYICKV--CDKSYTHPSSLRKHMKVHESQ 413


>gi|133922582 zinc finger protein 358 [Homo sapiens]
          Length = 568

 Score =  127 bits (320), Expect = 2e-29
 Identities = 104/313 (33%), Positives = 130/313 (41%), Gaps = 57/313 (18%)

Query: 202 CCAAYEQQEELVRHIEKSHIDQRKGEDFTCFWAGCVRRYKPFNARYKLLIHMRVHSGEKP 261
           C   + Q   L++H+ ++H  +R    + C   G     K F     LL H R H+ E+P
Sbjct: 268 CAKGFGQGSALLKHL-RTHTGERP---YPCPQCG-----KAFGQSSALLQHQRTHTAERP 318

Query: 262 NKCMFEGCSKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDRAKHQRTHLDTKP 321
            +C    C KAF +  NL+ HLR HTGE+PY C H  C KAF  SS   +H   H   +P
Sbjct: 319 YRCPH--CGKAFGQSSNLQHHLRIHTGERPYACPH--CSKAFGQSSALLQHLHVHSGERP 374

Query: 322 YACQIPGCSKRYTDPSSLRKHVKAHSAKEQQVRKKLHAGPDTEADVLTECLVLQQLHTST 381
           Y CQ+  C K +   SSL KH            K++H G    A              + 
Sbjct: 375 YRCQL--CGKAFGQASSLTKH------------KRVHEGAAAAA-------------AAA 407

Query: 382 QLAASDGKGGCGLGQELLPGVYPGSITPHNGLASGLLPPAHDVPSRHHPLDATTSSHHHL 441
             AA+    G GLG    PG+ P S+    G  S L P A  V      L   TSS  + 
Sbjct: 408 AAAAAAAAAGLGLG----PGLSPASMM-RPGQVSLLGPDAVSVLGSGLGLSPGTSSGRNP 462

Query: 442 SPLPMAESTRDGLGPGLL-SPIVSPLKG--LGPPPLPPSSQSHSPGGQPFPTLPSKPSYP 498
            P         G GPG L  P   PL G    P P P  S     G    P L   P   
Sbjct: 463 DP---------GSGPGTLPDPSSKPLPGSRSTPSPTPVESSDPKAGHDAGPDLVPSPDLD 513

Query: 499 PFQSPPPPPLPSP 511
           P  SP P P+PSP
Sbjct: 514 PVPSPDPDPVPSP 526



 Score = 68.2 bits (165), Expect = 2e-11
 Identities = 36/94 (38%), Positives = 51/94 (54%), Gaps = 6/94 (6%)

Query: 257 SGEKPNKCMFEGCSKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDRAKHQRTH 316
           S  +P  C    C +AF R   L  H R+H+GEKPY C  P C K+FS+ +  A+H+  H
Sbjct: 146 SPPRPFSC--PDCGRAFRRSSGLSQHRRTHSGEKPYRC--PDCGKSFSHGATLAQHRGIH 201

Query: 317 LDTKPYACQIPGCSKRYTDPSSLRKHVKAHSAKE 350
              +PY C    C K +   S+L KH  +HS ++
Sbjct: 202 TGARPYQC--AACGKAFGWRSTLLKHRSSHSGEK 233


>gi|116014328 zinc finger protein 143 [Homo sapiens]
          Length = 638

 Score =  125 bits (314), Expect = 1e-28
 Identities = 56/131 (42%), Positives = 80/131 (61%), Gaps = 4/131 (3%)

Query: 218 KSHIDQRKGED-FTCFWAGCVRRYKPFNARYKLLIHMRVHSGEKPNKCMFEGCSKAFSRL 276
           KSH+    GE  + C    C + +K      K   H+R H+GE+P KC FEGC ++F+  
Sbjct: 285 KSHVRTHTGEKPYRCSEDNCTKSFKTSGDLQK---HIRTHTGERPFKCPFEGCGRSFTTS 341

Query: 277 ENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDRAKHQRTHLDTKPYACQIPGCSKRYTDP 336
              K+H+R+HTGE+PY C  PGC +AF+++++   H R H   KPY C +PGC KR+T+ 
Sbjct: 342 NIRKVHVRTHTGERPYYCTEPGCGRAFASATNYKNHVRIHTGEKPYVCTVPGCDKRFTEY 401

Query: 337 SSLRKHVKAHS 347
           SSL KH   H+
Sbjct: 402 SSLYKHHVVHT 412



 Score =  115 bits (287), Expect = 2e-25
 Identities = 62/176 (35%), Positives = 91/176 (51%), Gaps = 14/176 (7%)

Query: 185 GLAGRVVAGRQA-------CRWVDCCAAYEQQEELVRHIEKSHIDQRKGEDFTCFWAGCV 237
           G A RV A  Q        C +  C   Y     L  H E+SH   R    + C  AGC 
Sbjct: 220 GHATRVTAKSQQSGEKAFRCEYDGCGKLYTTAHHLKVH-ERSHTGDRP---YQCEHAGCG 275

Query: 238 RRYKPFNARYKLLIHMRVHSGEKPNKCMFEGCSKAFSRLENLKIHLRSHTGEKPYLCQHP 297
              K F   Y L  H+R H+GEKP +C  + C+K+F    +L+ H+R+HTGE+P+ C   
Sbjct: 276 ---KAFATGYGLKSHVRTHTGEKPYRCSEDNCTKSFKTSGDLQKHIRTHTGERPFKCPFE 332

Query: 298 GCQKAFSNSSDRAKHQRTHLDTKPYACQIPGCSKRYTDPSSLRKHVKAHSAKEQQV 353
           GC ++F+ S+ R  H RTH   +PY C  PGC + +   ++ + HV+ H+ ++  V
Sbjct: 333 GCGRSFTTSNIRKVHVRTHTGERPYYCTEPGCGRAFASATNYKNHVRIHTGEKPYV 388



 Score =  108 bits (271), Expect = 1e-23
 Identities = 64/173 (36%), Positives = 89/173 (51%), Gaps = 12/173 (6%)

Query: 181 GLGLGLAGRVVAGRQA--CRWVDCCAAYEQQEELVRHIEKSHIDQRKGEDFTCFWAGCVR 238
           G GL    R   G +   C   +C  +++   +L +HI ++H  +R    F C + GC R
Sbjct: 281 GYGLKSHVRTHTGEKPYRCSEDNCTKSFKTSGDLQKHI-RTHTGERP---FKCPFEGCGR 336

Query: 239 RYKPFNARYKLLIHMRVHSGEKPNKCMFEGCSKAFSRLENLKIHLRSHTGEKPYLCQHPG 298
            +   N R    +H+R H+GE+P  C   GC +AF+   N K H+R HTGEKPY+C  PG
Sbjct: 337 SFTTSNIRK---VHVRTHTGERPYYCTEPGCGRAFASATNYKNHVRIHTGEKPYVCTVPG 393

Query: 299 CQKAFSNSSDRAKHQRTHLDTKPYACQIPGCSKRYTDPSSLRKHVK-AHSAKE 350
           C K F+  S   KH   H  +KPY C    C K Y   S+L  H + AH+  E
Sbjct: 394 CDKRFTEYSSLYKHHVVHTHSKPYNCN--HCGKTYKQISTLAMHKRTAHNDTE 444


>gi|112790163 metal-regulatory transcription factor 1 [Homo sapiens]
          Length = 753

 Score =  119 bits (299), Expect = 6e-27
 Identities = 101/330 (30%), Positives = 138/330 (41%), Gaps = 35/330 (10%)

Query: 197 CRWVDCCAAYEQQEELVRHIEKSHIDQRKGEDFTCFWAGCVRRYKPFNARYKLLIHMRVH 256
           C    C  A+     L  H+        K + F C   GC    K FN  Y+L  H R+H
Sbjct: 172 CNQEGCGKAFLTSYSLRIHVRV----HTKEKPFECDVQGCE---KAFNTLYRLKAHQRLH 224

Query: 257 SGEKPNKCMFEGCSKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDRAKHQRTH 316
           +G+  N C  EGCSK F+ L +L+ H+R+HTGEKP+ C H GC KAF+ S     H RTH
Sbjct: 225 TGKTFN-CESEGCSKYFTTLSDLRKHIRTHTGEKPFRCDHDGCGKAFAASHHLKTHVRTH 283

Query: 317 LDTKPYACQIPGCSKRYTDPSSLRKHVKAHSAKEQQVRK-KLHAGPDTEADVLTECLV-L 374
              +P+ C   GC K ++   SL+ H+K H  K         H G +     L  CL  L
Sbjct: 284 TGERPFFCPSNGCEKTFSTQYSLKSHMKGHDNKGHSYNALPQHNGSEDTNHSL--CLSDL 341

Query: 375 QQLHTSTQLAASDGKGGCGLGQELLPGVYPGSITPHNGLASGLLPPAHDVPSRHHPLDAT 434
             L T ++L  +        GQ+L       +I+P   +   +   + D   +  P    
Sbjct: 342 SLLSTDSELREN---SSTTQGQDL------STISPAI-IFESMFQNSDDTAIQEDPQQTA 391

Query: 435 TSSHHHLSPLPMAESTRD-----GLGPGLLSPIVSPLKGLGPPPLPPSSQSHSPGGQPFP 489
           + +         AES  D     G    L  P+V    GL  PP P    S      P P
Sbjct: 392 SLTESFNGD---AESVSDVPPSTGNSASLSLPLVLQ-PGLSEPPQPLLPASAPSAPPPAP 447

Query: 490 TLPSKPSYPPFQSPP----PPPLPSPQGYQ 515
           +L        F +PP    PP +P P   Q
Sbjct: 448 SLGPGSQQAAFGNPPALLQPPEVPVPHSTQ 477



 Score = 97.1 bits (240), Expect = 4e-20
 Identities = 49/122 (40%), Positives = 66/122 (54%), Gaps = 4/122 (3%)

Query: 229 FTCFWAGCVRRYKPFNARYKLLIHMRVHSGEKPNKCMFEGCSKAFSRLENLKIHLRSHTG 288
           + C + GC R Y        L  H + H GE    C  EGC KAF    +L+IH+R HT 
Sbjct: 140 YQCTFEGCPRTYSTAG---NLRTHQKTHRGEYTFVCNQEGCGKAFLTSYSLRIHVRVHTK 196

Query: 289 EKPYLCQHPGCQKAFSNSSDRAKHQRTHLDTKPYACQIPGCSKRYTDPSSLRKHVKAHSA 348
           EKP+ C   GC+KAF+       HQR H   K + C+  GCSK +T  S LRKH++ H+ 
Sbjct: 197 EKPFECDVQGCEKAFNTLYRLKAHQRLHTG-KTFNCESEGCSKYFTTLSDLRKHIRTHTG 255

Query: 349 KE 350
           ++
Sbjct: 256 EK 257



 Score = 78.2 bits (191), Expect = 2e-14
 Identities = 33/90 (36%), Positives = 47/90 (52%)

Query: 260 KPNKCMFEGCSKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDRAKHQRTHLDT 319
           K  +C FEGC + +S   NL+ H ++H GE  ++C   GC KAF  S     H R H   
Sbjct: 138 KRYQCTFEGCPRTYSTAGNLRTHQKTHRGEYTFVCNQEGCGKAFLTSYSLRIHVRVHTKE 197

Query: 320 KPYACQIPGCSKRYTDPSSLRKHVKAHSAK 349
           KP+ C + GC K +     L+ H + H+ K
Sbjct: 198 KPFECDVQGCEKAFNTLYRLKAHQRLHTGK 227



 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 37/135 (27%), Positives = 57/135 (42%), Gaps = 18/135 (13%)

Query: 251 IHMRVHSGEKPNKCMFEGCSKAFSRLENLKIHLRSHTGE------KPYLCQHPGCQKAFS 304
           IH+ ++ G  P     EG +          + L+S   E      K Y C   GC + +S
Sbjct: 103 IHLTINPGSTPMPRNIEGAT----------LTLQSECPETKRKEVKRYQCTFEGCPRTYS 152

Query: 305 NSSDRAKHQRTHLDTKPYACQIPGCSKRYTDPSSLRKHVKAHSAKEQQVRKKLHAGPDTE 364
            + +   HQ+TH     + C   GC K +    SLR HV+ H+ KE+     +  G +  
Sbjct: 153 TAGNLRTHQKTHRGEYTFVCNQEGCGKAFLTSYSLRIHVRVHT-KEKPFECDVQ-GCEKA 210

Query: 365 ADVLTECLVLQQLHT 379
            + L      Q+LHT
Sbjct: 211 FNTLYRLKAHQRLHT 225


>gi|21361146 zinc finger protein 76 (expressed in testis) [Homo
           sapiens]
          Length = 570

 Score =  116 bits (291), Expect = 5e-26
 Identities = 53/131 (40%), Positives = 78/131 (59%), Gaps = 4/131 (3%)

Query: 218 KSHIDQRKGED-FTCFWAGCVRRYKPFNARYKLLIHMRVHSGEKPNKCMFEGCSKAFSRL 276
           KSH+    GE  + C    C + +K      K   H+R H+GE+P +C FEGC ++F+  
Sbjct: 213 KSHVRTHTGEKPYKCPEELCSKAFKTSGDLQK---HVRTHTGERPFQCPFEGCGRSFTTS 269

Query: 277 ENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDRAKHQRTHLDTKPYACQIPGCSKRYTDP 336
              K+H+R+HTGE+PY C  P C + F+++++   H R H   KPY C +PGC KR+T+ 
Sbjct: 270 NIRKVHVRTHTGERPYTCPEPHCGRGFTSATNYKNHVRIHTGEKPYVCTVPGCGKRFTEY 329

Query: 337 SSLRKHVKAHS 347
           SSL KH   H+
Sbjct: 330 SSLYKHHVVHT 340



 Score =  115 bits (289), Expect = 9e-26
 Identities = 60/164 (36%), Positives = 84/164 (51%), Gaps = 7/164 (4%)

Query: 201 DCCAAYEQQEELVRH---IEKSHIDQRKGED-FTCFWAGCVRRYKPFNARYKLLIHMRVH 256
           D   A EQ    V H   I ++   Q+ G+  F C + GC R Y      + L +H R H
Sbjct: 133 DAVVALEQYASKVLHDSQIPRNGKGQQVGDRAFRCGYKGCGRLY---TTAHHLKVHERAH 189

Query: 257 SGEKPNKCMFEGCSKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDRAKHQRTH 316
           +G++P +C F  C KAF+    LK H+R+HTGEKPY C    C KAF  S D  KH RTH
Sbjct: 190 TGDRPYRCDFPSCGKAFATGYGLKSHVRTHTGEKPYKCPEELCSKAFKTSGDLQKHVRTH 249

Query: 317 LDTKPYACQIPGCSKRYTDPSSLRKHVKAHSAKEQQVRKKLHAG 360
              +P+ C   GC + +T  +  + HV+ H+ +      + H G
Sbjct: 250 TGERPFQCPFEGCGRSFTTSNIRKVHVRTHTGERPYTCPEPHCG 293



 Score =  111 bits (278), Expect = 2e-24
 Identities = 57/157 (36%), Positives = 84/157 (53%), Gaps = 7/157 (4%)

Query: 197 CRWVDCCAAYEQQEELVRHIEKSHIDQRKGEDFTCFWAGCVRRYKPFNARYKLLIHMRVH 256
           C +  C   Y     L  H E++H   R    + C +  C    K F   Y L  H+R H
Sbjct: 167 CGYKGCGRLYTTAHHLKVH-ERAHTGDRP---YRCDFPSCG---KAFATGYGLKSHVRTH 219

Query: 257 SGEKPNKCMFEGCSKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDRAKHQRTH 316
           +GEKP KC  E CSKAF    +L+ H+R+HTGE+P+ C   GC ++F+ S+ R  H RTH
Sbjct: 220 TGEKPYKCPEELCSKAFKTSGDLQKHVRTHTGERPFQCPFEGCGRSFTTSNIRKVHVRTH 279

Query: 317 LDTKPYACQIPGCSKRYTDPSSLRKHVKAHSAKEQQV 353
              +PY C  P C + +T  ++ + HV+ H+ ++  V
Sbjct: 280 TGERPYTCPEPHCGRGFTSATNYKNHVRIHTGEKPYV 316



 Score =  103 bits (257), Expect = 5e-22
 Identities = 56/150 (37%), Positives = 77/150 (51%), Gaps = 10/150 (6%)

Query: 202 CCAAYEQQEELVRHIEKSHIDQRKGEDFTCFWAGCVRRYKPFNARYKLLIHMRVHSGEKP 261
           C  A++   +L +H+ ++H  +R    F C + GC R +   N R    +H+R H+GE+P
Sbjct: 232 CSKAFKTSGDLQKHV-RTHTGERP---FQCPFEGCGRSFTTSNIRK---VHVRTHTGERP 284

Query: 262 NKCMFEGCSKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDRAKHQRTHLDTKP 321
             C    C + F+   N K H+R HTGEKPY+C  PGC K F+  S   KH   H   KP
Sbjct: 285 YTCPEPHCGRGFTSATNYKNHVRIHTGEKPYVCTVPGCGKRFTEYSSLYKHHVVHTHCKP 344

Query: 322 YACQIPGCSKRYTDPSSLRKHVK-AHSAKE 350
           Y C    C K Y   S+L  H + AH   E
Sbjct: 345 YTCST--CGKTYRQTSTLAMHKRSAHGELE 372


>gi|38570115 zinc finger protein 362 [Homo sapiens]
          Length = 420

 Score =  112 bits (280), Expect = 1e-24
 Identities = 97/339 (28%), Positives = 139/339 (41%), Gaps = 73/339 (21%)

Query: 19  GLHPDLDLPGRSLATPAPSCYLLGSEPSS---GLGLQPETHLPEGSLKRCCVLGLPPTSP 75
           GLHP         A P P   L     +S   GLGL   T  P  S           T  
Sbjct: 93  GLHPQ--------AVPQPDVALHARPATSTVTGLGLSTRT--PSVSTSESSAGAGTGTGT 142

Query: 76  ASSSPCASSDVTSIIRSSQTSLVTCVNGLRSPPLTGDLGGPSKRARPGPASTDSHEGSLQ 135
           ++ S   ++  + +I SS T     ++G+ SPPL   +         GP  ++     ++
Sbjct: 143 STPSTPTTTSQSRLIASSPT----LISGITSPPLLDSIKTIQGHGLLGPPKSERGRKKIK 198

Query: 136 LEACRKASFLKQEPADEFSELFGPHQQGLPP----PYPLSQLPPGPSLGGLGLGLAGRVV 191
            E                         G PP    PYP+                +G   
Sbjct: 199 AE-----------------------NPGGPPVLVVPYPILA--------------SGETA 221

Query: 192 AGRQACRWVDCCAAYEQQEELVRHIEKSHIDQRKGEDFTCFWAGCVRRYKPF-NARYKLL 250
              +  R   C   +  + E+  H  KSH + +  +        C    K F NA Y L 
Sbjct: 222 KEGKTYRCKVCPLTFFTKSEMQIH-SKSHTEAKPHK--------CPHCSKSFANASY-LA 271

Query: 251 IHMRVHSGEKPNKCMFEGCSKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDRA 310
            H+R+H G KP  C +  C K+F +L +L+ H R HTG++PY C HPGC+KAF+  S+  
Sbjct: 272 QHLRIHLGVKPYHCSY--CDKSFRQLSHLQQHTRIHTGDRPYKCPHPGCEKAFTQLSNLQ 329

Query: 311 KHQRTHLDTKPYACQIPGCSKRYTDPSSLRKHVKAHSAK 349
            HQR H   KPY C  P C + Y+D +SL+ H+ AH+ K
Sbjct: 330 SHQRQHNKDKPYKC--PNCYRAYSDSASLQIHLSAHAIK 366


>gi|117956407 zinc finger protein 568 [Homo sapiens]
          Length = 644

 Score =  109 bits (273), Expect = 7e-24
 Identities = 64/191 (33%), Positives = 99/191 (51%), Gaps = 19/191 (9%)

Query: 189 RVVAGRQACRWVDCCAAYEQQEELVRHIEKSHIDQRKGEDFTCFWAGCVRRYKPFNARYK 248
           R+  G +     DC  A+ Q+  L+ H E+ H  ++  E        C    K F+ +  
Sbjct: 298 RIHTGEKPYACKDCWKAFSQKSNLIEH-ERIHTGEKPYE--------CKECGKSFSQKQN 348

Query: 249 LLIHMRVHSGEKPNKCMFEGCSKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSD 308
           L+ H ++H+GEKP  C    C +AFSR+ ++ +H+RSHTGEKPY C    C KAFS  S 
Sbjct: 349 LIEHEKIHTGEKPYAC--NECGRAFSRMSSVTLHMRSHTGEKPYKCNK--CGKAFSQCSV 404

Query: 309 RAKHQRTHLDTKPYACQIPGCSKRYTDPSSLRKHVKAHSAKEQQVRKKLHAGPDTEADVL 368
              H R+H   KPY C    C K ++  SSL  H++ H+A++    K+       + +++
Sbjct: 405 FIIHMRSHTGEKPYVCS--ECGKAFSQSSSLTVHMRNHTAEKPYECKECGKAFSRKENLI 462

Query: 369 TECLVLQQLHT 379
           T     Q++HT
Sbjct: 463 TH----QKIHT 469



 Score =  106 bits (264), Expect = 7e-23
 Identities = 63/165 (38%), Positives = 86/165 (52%), Gaps = 15/165 (9%)

Query: 189 RVVAGRQACRWVDCCAAYEQQEELVRHIEKSHIDQRKGEDFTCFWAGCVRRYKPFNARYK 248
           R+  G +      C  A+ Q+  L  H EK H  ++    + C   G     K F+ R  
Sbjct: 494 RIHTGEKPYACTVCGKAFSQKSNLTEH-EKIHTGEKP---YHCNQCG-----KAFSQRQN 544

Query: 249 LLIHMRVHSGEKPNKCMFEGCSKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSD 308
           LL H ++H+GEKP KC    C KAFSR+ +L +H+RSHTGEKPY C    C KAFS  S 
Sbjct: 545 LLEHEKIHTGEKPFKC--NECGKAFSRISSLTLHVRSHTGEKPYECNK--CGKAFSQCSL 600

Query: 309 RAKHQRTHLDTKPYACQIPGCSKRYTDPSSLRKHVKAHSAKEQQV 353
              H R+H   KP+ C    C K ++  +SL  H + H+ +  QV
Sbjct: 601 LIIHMRSHTGEKPFECN--ECGKAFSQRASLSIHKRGHTGERHQV 643



 Score =  101 bits (251), Expect = 2e-21
 Identities = 58/149 (38%), Positives = 81/149 (54%), Gaps = 15/149 (10%)

Query: 202 CCAAYEQQEELVRHIEKSHIDQRKGEDFTCFWAGCVRRYKPFNARYKLLIHMRVHSGEKP 261
           C  A+ Q    + H+ +SH  ++    + C   G     K F+    L +HMR H+ EKP
Sbjct: 395 CGKAFSQCSVFIIHM-RSHTGEKP---YVCSECG-----KAFSQSSSLTVHMRNHTAEKP 445

Query: 262 NKCMFEGCSKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDRAKHQRTHLDTKP 321
            +C  + C KAFSR ENL  H + HTGEKPY C    C KAF   S+  +HQR H   KP
Sbjct: 446 YEC--KECGKAFSRKENLITHQKIHTGEKPYECSE--CGKAFIQMSNLIRHQRIHTGEKP 501

Query: 322 YACQIPGCSKRYTDPSSLRKHVKAHSAKE 350
           YAC +  C K ++  S+L +H K H+ ++
Sbjct: 502 YACTV--CGKAFSQKSNLTEHEKIHTGEK 528



 Score = 96.3 bits (238), Expect = 8e-20
 Identities = 62/178 (34%), Positives = 97/178 (54%), Gaps = 22/178 (12%)

Query: 186 LAGRVVAGRQACRWVDCCA---AYEQQEELVRHIEKSHIDQRKGEDFTCFWAGC----VR 238
           L+  +V  RQ+  + DC +     E   +L+R+ EK  + +++  +F   +  C    V 
Sbjct: 164 LSSDIVTSRQS--FYDCDSLDKGLEHNLDLLRY-EKGCVREKQSNEFGKPFYHCASYVVT 220

Query: 239 RYK------PFNARYKLLIHMRVHSGEKPNKCMFEGCSKAFSRLENLKIHLRSHTGEKPY 292
            +K       F+ ++ L+ H R+H+GEKP +C  + C KAFSR ENL  H + HTGEKPY
Sbjct: 221 PFKCNQCGQDFSHKFDLIRHERIHAGEKPYEC--KECGKAFSRKENLITHQKIHTGEKPY 278

Query: 293 LCQHPGCQKAFSNSSDRAKHQRTHLDTKPYACQIPGCSKRYTDPSSLRKHVKAHSAKE 350
            C    C KAF   S+  +H R H   KPYAC+   C K ++  S+L +H + H+ ++
Sbjct: 279 KCNE--CGKAFIQMSNLIRHHRIHTGEKPYACK--DCWKAFSQKSNLIEHERIHTGEK 332


>gi|64368880 zinc finger and SCAN domain containing 25 [Homo
           sapiens]
          Length = 544

 Score =  109 bits (273), Expect = 7e-24
 Identities = 56/151 (37%), Positives = 91/151 (60%), Gaps = 16/151 (10%)

Query: 200 VDCCAAYEQQEELVRHIEKSHIDQRKGEDFTCFWAGCVRRYKPFNARYKLLIHMRVHSGE 259
           V+C   +  +E L++H +++H+ +R           C   +K F+ R+ L +H R H+GE
Sbjct: 378 VECGKGFTLREYLMKH-QRTHLGKRPYV--------CSECWKTFSQRHHLEVHQRSHTGE 428

Query: 260 KPNKCMFEGCSKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDRAKHQRTHLDT 319
           KP KC    C K+FSR ++L++H R+HTGEKPY C+   C K+FS +++ A H+R H   
Sbjct: 429 KPYKC--GDCWKSFSRRQHLQVHRRTHTGEKPYTCE---CGKSFSRNANLAVHRRAHTGE 483

Query: 320 KPYACQIPGCSKRYTDPSSLRKHVKAHSAKE 350
           KPY CQ+  C KR++    L +H + H+ ++
Sbjct: 484 KPYGCQV--CGKRFSKGERLVRHQRIHTGEK 512



 Score =  100 bits (248), Expect = 5e-21
 Identities = 57/154 (37%), Positives = 78/154 (50%), Gaps = 16/154 (10%)

Query: 201 DCCAAYEQQEELVRHIEKSHIDQRKGEDFTCFWAGCVRRYKPFNARYKLLIHMRVHSGEK 260
           +C   + Q+  L  H ++SH  ++  +   C        +K F+ R  L +H R H+GEK
Sbjct: 407 ECWKTFSQRHHLEVH-QRSHTGEKPYKCGDC--------WKSFSRRQHLQVHRRTHTGEK 457

Query: 261 PNKCMFEGCSKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDRAKHQRTHLDTK 320
           P  C    C K+FSR  NL +H R+HTGEKPY CQ   C K FS      +HQR H   K
Sbjct: 458 PYTCE---CGKSFSRNANLAVHRRAHTGEKPYGCQ--VCGKRFSKGERLVRHQRIHTGEK 512

Query: 321 PYACQIPGCSKRYTDPSSLRKHVKAHSAKEQQVR 354
           PY C  P C + +   S L +H K    +E  V+
Sbjct: 513 PYHC--PACGRSFNQRSILNRHQKTQHRQEPLVQ 544



 Score = 94.0 bits (232), Expect = 4e-19
 Identities = 55/150 (36%), Positives = 78/150 (52%), Gaps = 17/150 (11%)

Query: 201 DCCAAYEQQEELVRHIEKSHIDQRKGEDFTCFWAGCVRRYKPFNARYKLLIHMRVHSGEK 260
           +C   + +   LVRH       QR  E+ +    GCV   K F  R  L+ H R H G++
Sbjct: 352 ECGKGFSRSSNLVRH-------QRTHEEKSY---GCVECGKGFTLREYLMKHQRTHLGKR 401

Query: 261 PNKCMFEGCSKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDRAKHQRTHLDTK 320
           P  C    C K FS+  +L++H RSHTGEKPY C    C K+FS       H+RTH   K
Sbjct: 402 PYVC--SECWKTFSQRHHLEVHQRSHTGEKPYKC--GDCWKSFSRRQHLQVHRRTHTGEK 457

Query: 321 PYACQIPGCSKRYTDPSSLRKHVKAHSAKE 350
           PY C+   C K ++  ++L  H +AH+ ++
Sbjct: 458 PYTCE---CGKSFSRNANLAVHRRAHTGEK 484



 Score = 46.6 bits (109), Expect = 7e-05
 Identities = 27/64 (42%), Positives = 33/64 (51%), Gaps = 5/64 (7%)

Query: 290 KPYLCQHPGCQKAFSNSSDRAKHQRTHLDTKPYACQIPGCSKRYTDPSSLRKHVKAHSAK 349
           KP+ C  P C K FS SS+  +HQRTH + K Y C    C K +T    L KH + H  K
Sbjct: 346 KPFQC--PECGKGFSRSSNLVRHQRTH-EEKSYGC--VECGKGFTLREYLMKHQRTHLGK 400

Query: 350 EQQV 353
              V
Sbjct: 401 RPYV 404


>gi|90193619 nuclear matrix transcription factor 4 isoform c [Homo
           sapiens]
          Length = 461

 Score =  107 bits (267), Expect = 3e-23
 Identities = 56/152 (36%), Positives = 80/152 (52%), Gaps = 13/152 (8%)

Query: 202 CCAAYEQQEELVRHIEKSHIDQRKGEDFTCFWAGCVRRYKPFNARYKLLIHMRVHSGEKP 261
           C   +  + E+  H  KSH + +  +        C    K F     L  H+R+HSG KP
Sbjct: 178 CSLTFYSKSEMQIH-SKSHTETKPHK--------CPHCSKTFANSSYLAQHIRIHSGAKP 228

Query: 262 NKCMFEGCSKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDRAKHQRTHLDTKP 321
             C F  C K+F +L +L+ H R HTG++PY C HPGC+KAF+  S+   H+R H   KP
Sbjct: 229 YSCNF--CEKSFRQLSHLQQHTRIHTGDRPYKCAHPGCEKAFTQLSNLQSHRRQHNKDKP 286

Query: 322 YACQIPGCSKRYTDPSSLRKHVKAHSAKEQQV 353
           + C    C + YTD +SL  H+  H+ K  +V
Sbjct: 287 FKCH--NCHRAYTDAASLEVHLSTHTVKHAKV 316


>gi|90193617 nuclear matrix transcription factor 4 isoform b [Homo
           sapiens]
          Length = 500

 Score =  107 bits (267), Expect = 3e-23
 Identities = 56/152 (36%), Positives = 80/152 (52%), Gaps = 13/152 (8%)

Query: 202 CCAAYEQQEELVRHIEKSHIDQRKGEDFTCFWAGCVRRYKPFNARYKLLIHMRVHSGEKP 261
           C   +  + E+  H  KSH + +  +        C    K F     L  H+R+HSG KP
Sbjct: 217 CSLTFYSKSEMQIH-SKSHTETKPHK--------CPHCSKTFANSSYLAQHIRIHSGAKP 267

Query: 262 NKCMFEGCSKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDRAKHQRTHLDTKP 321
             C F  C K+F +L +L+ H R HTG++PY C HPGC+KAF+  S+   H+R H   KP
Sbjct: 268 YSCNF--CEKSFRQLSHLQQHTRIHTGDRPYKCAHPGCEKAFTQLSNLQSHRRQHNKDKP 325

Query: 322 YACQIPGCSKRYTDPSSLRKHVKAHSAKEQQV 353
           + C    C + YTD +SL  H+  H+ K  +V
Sbjct: 326 FKCH--NCHRAYTDAASLEVHLSTHTVKHAKV 355


>gi|90193615 nuclear matrix transcription factor 4 isoform b [Homo
           sapiens]
          Length = 500

 Score =  107 bits (267), Expect = 3e-23
 Identities = 56/152 (36%), Positives = 80/152 (52%), Gaps = 13/152 (8%)

Query: 202 CCAAYEQQEELVRHIEKSHIDQRKGEDFTCFWAGCVRRYKPFNARYKLLIHMRVHSGEKP 261
           C   +  + E+  H  KSH + +  +        C    K F     L  H+R+HSG KP
Sbjct: 217 CSLTFYSKSEMQIH-SKSHTETKPHK--------CPHCSKTFANSSYLAQHIRIHSGAKP 267

Query: 262 NKCMFEGCSKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDRAKHQRTHLDTKP 321
             C F  C K+F +L +L+ H R HTG++PY C HPGC+KAF+  S+   H+R H   KP
Sbjct: 268 YSCNF--CEKSFRQLSHLQQHTRIHTGDRPYKCAHPGCEKAFTQLSNLQSHRRQHNKDKP 325

Query: 322 YACQIPGCSKRYTDPSSLRKHVKAHSAKEQQV 353
           + C    C + YTD +SL  H+  H+ K  +V
Sbjct: 326 FKCH--NCHRAYTDAASLEVHLSTHTVKHAKV 355


>gi|90193613 nuclear matrix transcription factor 4 isoform a [Homo
           sapiens]
          Length = 516

 Score =  107 bits (267), Expect = 3e-23
 Identities = 56/152 (36%), Positives = 80/152 (52%), Gaps = 13/152 (8%)

Query: 202 CCAAYEQQEELVRHIEKSHIDQRKGEDFTCFWAGCVRRYKPFNARYKLLIHMRVHSGEKP 261
           C   +  + E+  H  KSH + +  +        C    K F     L  H+R+HSG KP
Sbjct: 233 CSLTFYSKSEMQIH-SKSHTETKPHK--------CPHCSKTFANSSYLAQHIRIHSGAKP 283

Query: 262 NKCMFEGCSKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDRAKHQRTHLDTKP 321
             C F  C K+F +L +L+ H R HTG++PY C HPGC+KAF+  S+   H+R H   KP
Sbjct: 284 YSCNF--CEKSFRQLSHLQQHTRIHTGDRPYKCAHPGCEKAFTQLSNLQSHRRQHNKDKP 341

Query: 322 YACQIPGCSKRYTDPSSLRKHVKAHSAKEQQV 353
           + C    C + YTD +SL  H+  H+ K  +V
Sbjct: 342 FKCH--NCHRAYTDAASLEVHLSTHTVKHAKV 371


>gi|90193611 nuclear matrix transcription factor 4 isoform a [Homo
           sapiens]
          Length = 516

 Score =  107 bits (267), Expect = 3e-23
 Identities = 56/152 (36%), Positives = 80/152 (52%), Gaps = 13/152 (8%)

Query: 202 CCAAYEQQEELVRHIEKSHIDQRKGEDFTCFWAGCVRRYKPFNARYKLLIHMRVHSGEKP 261
           C   +  + E+  H  KSH + +  +        C    K F     L  H+R+HSG KP
Sbjct: 233 CSLTFYSKSEMQIH-SKSHTETKPHK--------CPHCSKTFANSSYLAQHIRIHSGAKP 283

Query: 262 NKCMFEGCSKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDRAKHQRTHLDTKP 321
             C F  C K+F +L +L+ H R HTG++PY C HPGC+KAF+  S+   H+R H   KP
Sbjct: 284 YSCNF--CEKSFRQLSHLQQHTRIHTGDRPYKCAHPGCEKAFTQLSNLQSHRRQHNKDKP 341

Query: 322 YACQIPGCSKRYTDPSSLRKHVKAHSAKEQQV 353
           + C    C + YTD +SL  H+  H+ K  +V
Sbjct: 342 FKCH--NCHRAYTDAASLEVHLSTHTVKHAKV 371


>gi|36054194 nuclear matrix transcription factor 4 isoform a [Homo
           sapiens]
          Length = 516

 Score =  107 bits (267), Expect = 3e-23
 Identities = 56/152 (36%), Positives = 80/152 (52%), Gaps = 13/152 (8%)

Query: 202 CCAAYEQQEELVRHIEKSHIDQRKGEDFTCFWAGCVRRYKPFNARYKLLIHMRVHSGEKP 261
           C   +  + E+  H  KSH + +  +        C    K F     L  H+R+HSG KP
Sbjct: 233 CSLTFYSKSEMQIH-SKSHTETKPHK--------CPHCSKTFANSSYLAQHIRIHSGAKP 283

Query: 262 NKCMFEGCSKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDRAKHQRTHLDTKP 321
             C F  C K+F +L +L+ H R HTG++PY C HPGC+KAF+  S+   H+R H   KP
Sbjct: 284 YSCNF--CEKSFRQLSHLQQHTRIHTGDRPYKCAHPGCEKAFTQLSNLQSHRRQHNKDKP 341

Query: 322 YACQIPGCSKRYTDPSSLRKHVKAHSAKEQQV 353
           + C    C + YTD +SL  H+  H+ K  +V
Sbjct: 342 FKCH--NCHRAYTDAASLEVHLSTHTVKHAKV 371


>gi|13129116 zinc finger protein 426 [Homo sapiens]
          Length = 554

 Score =  107 bits (266), Expect = 4e-23
 Identities = 63/152 (41%), Positives = 85/152 (55%), Gaps = 15/152 (9%)

Query: 195 QACRWVDCCAAYEQQEELVRHIEKSHIDQRKGEDFTCFWAGCVRRYKPFNARYKLLIHMR 254
           +AC    C   +     L  H+ ++H  Q+    +TC   G     K FN    L IHMR
Sbjct: 418 KACECKICGKVFGYPSCLNNHM-RTHSAQKP---YTCKECG-----KAFNYSTHLKIHMR 468

Query: 255 VHSGEKPNKCMFEGCSKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDRAKHQR 314
           +H+GEKP +C  + C KAFS   + +IH R+HTGEKPY C+   C KAF+ SS    H++
Sbjct: 469 IHTGEKPYEC--KQCGKAFSHSSSFQIHERTHTGEKPYECKE--CGKAFTCSSSFRIHEK 524

Query: 315 THLDTKPYACQIPGCSKRYTDPSSLRKHVKAH 346
           TH + KPY CQ   C K Y+ P SLR+H + H
Sbjct: 525 THTEEKPYKCQ--QCGKAYSHPRSLRRHEQIH 554



 Score = 98.2 bits (243), Expect = 2e-20
 Identities = 62/162 (38%), Positives = 84/162 (51%), Gaps = 15/162 (9%)

Query: 189 RVVAGRQACRWVDCCAAYEQQEELVRHIEKSHIDQRKGEDFTCFWAGCVRRYKPFNARYK 248
           R   G +    V+C  A+     L  H+ ++H +++  E   C         K F     
Sbjct: 384 RTHTGEKPFVCVECGKAFAVSSNLSGHL-RTHTEEKACECKICG--------KVFGYPSC 434

Query: 249 LLIHMRVHSGEKPNKCMFEGCSKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSD 308
           L  HMR HS +KP  C  + C KAF+   +LKIH+R HTGEKPY C+   C KAFS+SS 
Sbjct: 435 LNNHMRTHSAQKPYTC--KECGKAFNYSTHLKIHMRIHTGEKPYECKQ--CGKAFSHSSS 490

Query: 309 RAKHQRTHLDTKPYACQIPGCSKRYTDPSSLRKHVKAHSAKE 350
              H+RTH   KPY C+   C K +T  SS R H K H+ ++
Sbjct: 491 FQIHERTHTGEKPYECK--ECGKAFTCSSSFRIHEKTHTEEK 530



 Score = 89.7 bits (221), Expect = 7e-18
 Identities = 44/102 (43%), Positives = 64/102 (62%), Gaps = 6/102 (5%)

Query: 249 LLIHMRVHSGEKPNKCMFEGCSKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSD 308
           L IHMR H+GEKP +C  + C KAF+   + +IH R+HTGEKPY+C+   C KAF+  S 
Sbjct: 295 LSIHMRTHTGEKPYEC--KECGKAFNYSNSFQIHGRTHTGEKPYVCKE--CGKAFTQYSG 350

Query: 309 RAKHQRTHLDTKPYACQIPGCSKRYTDPSSLRKHVKAHSAKE 350
            + H R+H   KPY C+   C K +   S L +H++ H+ ++
Sbjct: 351 LSMHVRSHSGDKPYECK--ECGKSFLTSSRLIQHIRTHTGEK 390



 Score = 87.0 bits (214), Expect = 5e-17
 Identities = 48/121 (39%), Positives = 69/121 (57%), Gaps = 6/121 (4%)

Query: 236 CVRRYKPFNARYKLLIHMRVHSGEKPNKCMFEGCSKAFSRLENLKIHLRSHTGEKPYLCQ 295
           C    K F     L +H+R HSG+KP +C  + C K+F     L  H+R+HTGEKP++C 
Sbjct: 338 CKECGKAFTQYSGLSMHVRSHSGDKPYEC--KECGKSFLTSSRLIQHIRTHTGEKPFVCV 395

Query: 296 HPGCQKAFSNSSDRAKHQRTHLDTKPYACQIPGCSKRYTDPSSLRKHVKAHSAKEQQVRK 355
              C KAF+ SS+ + H RTH + K   C+I  C K +  PS L  H++ HSA++    K
Sbjct: 396 E--CGKAFAVSSNLSGHLRTHTEEKACECKI--CGKVFGYPSCLNNHMRTHSAQKPYTCK 451

Query: 356 K 356
           +
Sbjct: 452 E 452



 Score = 78.6 bits (192), Expect = 2e-14
 Identities = 51/145 (35%), Positives = 71/145 (48%), Gaps = 13/145 (8%)

Query: 238 RRYKP-FNARYKLLIHMRVHSGEKPNKCMFEGCSKAFSRLENLKIHLRSHTGEKPYLCQH 296
           R Y P F     L + +   + +KP KC  + C K +     L IH+R+HTGEKPY C+ 
Sbjct: 255 RNYGPGFIDSTSLSVLIETLNAKKPYKC--KECGKGYRYPAYLSIHMRTHTGEKPYECKE 312

Query: 297 PGCQKAFSNSSDRAKHQRTHLDTKPYACQIPGCSKRYTDPSSLRKHVKAHSAKEQQVRKK 356
             C KAF+ S+    H RTH   KPY C+   C K +T  S L  HV++HS        K
Sbjct: 313 --CGKAFNYSNSFQIHGRTHTGEKPYVCK--ECGKAFTQYSGLSMHVRSHSG------DK 362

Query: 357 LHAGPDTEADVLTECLVLQQLHTST 381
            +   +     LT   ++Q + T T
Sbjct: 363 PYECKECGKSFLTSSRLIQHIRTHT 387


>gi|209180475 nuclear matrix transcription factor 4 isoform d [Homo
           sapiens]
          Length = 577

 Score =  106 bits (264), Expect = 7e-23
 Identities = 50/118 (42%), Positives = 68/118 (57%), Gaps = 4/118 (3%)

Query: 236 CVRRYKPFNARYKLLIHMRVHSGEKPNKCMFEGCSKAFSRLENLKIHLRSHTGEKPYLCQ 295
           C    K F     L  H+R+HSG KP  C +  C KAF +L +L+ H R HTG++PY C 
Sbjct: 319 CPHCSKTFANTSYLAQHLRIHSGAKPYNCSY--CQKAFRQLSHLQQHTRIHTGDRPYKCA 376

Query: 296 HPGCQKAFSNSSDRAKHQRTHLDTKPYACQIPGCSKRYTDPSSLRKHVKAHSAKEQQV 353
           HPGC+KAF+  S+   H+R H   KP+ C    C + YTD +SL  H+  H+ K  +V
Sbjct: 377 HPGCEKAFTQLSNLQSHRRQHNKDKPFKCH--NCHRAYTDAASLEVHLSTHTVKHAKV 432



 Score = 83.2 bits (204), Expect = 7e-16
 Identities = 54/177 (30%), Positives = 72/177 (40%), Gaps = 42/177 (23%)

Query: 202 CCAAYEQQEELVRHIEKSHIDQRKGEDFTCFWAGCVRRYKPFNARYKLLIHMRVHSGEKP 261
           C   +  + E+  H  KSH + +  +        C    K F     L  H+R+HSG KP
Sbjct: 233 CSLTFYSKSEMQIH-SKSHTETKPHK--------CPHCSKTFANSSYLAQHIRIHSGAKP 283

Query: 262 NKCMF-------------------------------EGCSKAFSRLENLKIHLRSHTGEK 290
             C F                                 CSK F+    L  HLR H+G K
Sbjct: 284 YSCNFCEKSFRQLSHLQQHTRIHSKMHTETIKPHKCPHCSKTFANTSYLAQHLRIHSGAK 343

Query: 291 PYLCQHPGCQKAFSNSSDRAKHQRTHLDTKPYACQIPGCSKRYTDPSSLRKHVKAHS 347
           PY C +  CQKAF   S   +H R H   +PY C  PGC K +T  S+L+ H + H+
Sbjct: 344 PYNCSY--CQKAFRQLSHLQQHTRIHTGDRPYKCAHPGCEKAFTQLSNLQSHRRQHN 398



 Score = 67.8 bits (164), Expect = 3e-11
 Identities = 34/87 (39%), Positives = 46/87 (52%), Gaps = 4/87 (4%)

Query: 269 CSKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDRAKHQRTHLDTKPYACQIPG 328
           CS  F     ++IH +SHT  KP+ C H  C K F+NSS  A+H R H   KPY+C    
Sbjct: 233 CSLTFYSKSEMQIHSKSHTETKPHKCPH--CSKTFANSSYLAQHIRIHSGAKPYSCNF-- 288

Query: 329 CSKRYTDPSSLRKHVKAHSAKEQQVRK 355
           C K +   S L++H + HS    +  K
Sbjct: 289 CEKSFRQLSHLQQHTRIHSKMHTETIK 315


>gi|239751768 PREDICTED: hypothetical protein XP_002347973 isoform 1
           [Homo sapiens]
          Length = 479

 Score =  106 bits (264), Expect = 7e-23
 Identities = 58/163 (35%), Positives = 86/163 (52%), Gaps = 15/163 (9%)

Query: 190 VVAGRQACRWVDCCAAYEQQEELVRHIEKSHIDQRKGEDFTCFWAGCVRRYKPFNARYKL 249
           V  G + C+  +C  ++ +  EL RH +++H  ++  E        C    K F    +L
Sbjct: 332 VHTGEKPCKCKECGKSFRRGSELTRH-QRAHTGEKPYE--------CKECEKAFTCSTEL 382

Query: 250 LIHMRVHSGEKPNKCMFEGCSKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDR 309
           + H +VH+GE+P+KC  + C KAF R   L  H RSHTGEKPY C+   C K F   S+ 
Sbjct: 383 VRHQKVHTGERPHKC--KECGKAFIRRSELTHHERSHTGEKPYECKE--CGKPFGGGSEL 438

Query: 310 AKHQRTHLDTKPYACQIPGCSKRYTDPSSLRKHVKAHSAKEQQ 352
           ++HQ+ H   KPY CQ   C K +   S L +H + HS +  +
Sbjct: 439 SRHQKIHTGEKPYECQ--QCGKAFIRASHLSQHQRIHSGQRSE 479



 Score = 79.3 bits (194), Expect = 9e-15
 Identities = 60/217 (27%), Positives = 91/217 (41%), Gaps = 43/217 (19%)

Query: 189 RVVAGRQACRWVDCCAAYEQQEELVRHIEKSHIDQRKGEDFTCFWAGCVRRYKPFNARYK 248
           R+  G +  +  +C  A+    +L  H ++ H D++  E        C    K F     
Sbjct: 191 RMHLGEKPYKCRECGKAFPSTAQLNLH-QRIHTDEKYYE--------CKECGKAFTRPSH 241

Query: 249 LLIHMRVHSGEKPNKCMFEG--------------------------CSKAFSRLENLKIH 282
           L  H R+H+GEKP+KC   G                          C K +S    L +H
Sbjct: 242 LFRHQRIHTGEKPHKCKECGKAFRYDTQLSLHQIIHTGERRYECRECGKVYSCASQLSLH 301

Query: 283 LRSHTGEKPYLCQHPGCQKAFSNSSDRAKHQRTHLDTKPYACQIPGCSKRYTDPSSLRKH 342
            R HTGEKP+ C+   C KAF + S   +HQ  H   KP  C+   C K +   S L +H
Sbjct: 302 QRIHTGEKPHECKE--CGKAFISDSHLIRHQSVHTGEKP--CKCKECGKSFRRGSELTRH 357

Query: 343 VKAHSAKEQQVRKKLHAGPDTEADVLTECLVLQQLHT 379
            +AH+ ++    K+     +      TE +  Q++HT
Sbjct: 358 QRAHTGEKPYECKEC----EKAFTCSTELVRHQKVHT 390



 Score = 75.1 bits (183), Expect = 2e-13
 Identities = 47/158 (29%), Positives = 80/158 (50%), Gaps = 15/158 (9%)

Query: 193 GRQACRWVDCCAAYEQQEELVRHIEKSHIDQRKGEDFTCFWAGCVRRYKPFNARYKLLIH 252
           G +  +  +C  A+    ++ +H ++ H+ ++    + C   G     K F +  +L +H
Sbjct: 167 GEKPHKCKECGKAFRSSSQISQH-QRMHLGEKP---YKCRECG-----KAFPSTAQLNLH 217

Query: 253 MRVHSGEKPNKCMFEGCSKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDRAKH 312
            R+H+ EK  +C  + C KAF+R  +L  H R HTGEKP+ C+   C KAF   +  + H
Sbjct: 218 QRIHTDEKYYEC--KECGKAFTRPSHLFRHQRIHTGEKPHKCKE--CGKAFRYDTQLSLH 273

Query: 313 QRTHLDTKPYACQIPGCSKRYTDPSSLRKHVKAHSAKE 350
           Q  H   + Y C+   C K Y+  S L  H + H+ ++
Sbjct: 274 QIIHTGERRYECR--ECGKVYSCASQLSLHQRIHTGEK 309



 Score = 66.2 bits (160), Expect = 8e-11
 Identities = 48/158 (30%), Positives = 73/158 (46%), Gaps = 23/158 (14%)

Query: 193 GRQACRWVDCCAAYEQQEELVRHIEKSHIDQRKGEDFTCFWAGCVRRYKPFNARYKLLIH 252
           G ++C    C  A+  Q   ++H E  H  +++ E        C    K FN+   L+ H
Sbjct: 85  GEKSCECRKCKNAFRYQSCPIQH-EIIHNKEKEPE--------CGECRKIFNSGSDLIKH 135

Query: 253 MRVHSGEKP---NKCMFEGCSKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDR 309
             +H  +K    NKC       AF+    +      +TGEKP+ C+   C KAF +SS  
Sbjct: 136 QTLHESKKHSENNKC-------AFNHDSGITQPQSINTGEKPHKCKE--CGKAFRSSSQI 186

Query: 310 AKHQRTHLDTKPYACQIPGCSKRYTDPSSLRKHVKAHS 347
           ++HQR HL  KPY C+   C K +   + L  H + H+
Sbjct: 187 SQHQRMHLGEKPYKCR--ECGKAFPSTAQLNLHQRIHT 222



 Score = 35.0 bits (79), Expect = 0.21
 Identities = 23/71 (32%), Positives = 30/71 (42%), Gaps = 4/71 (5%)

Query: 286 HTGEKPYLCQHPGCQKAFSNSSDRAKHQRTHLDTKPYACQIPGCSKRYTDPSSLRKHVKA 345
           HTGEK   C+   C+ AF   S   +H+  H   K   C    C K +   S L KH   
Sbjct: 83  HTGEKSCECRK--CKNAFRYQSCPIQHEIIHNKEKEPECG--ECRKIFNSGSDLIKHQTL 138

Query: 346 HSAKEQQVRKK 356
           H +K+     K
Sbjct: 139 HESKKHSENNK 149


>gi|239751766 PREDICTED: hypothetical protein XP_002347974 isoform 2
           [Homo sapiens]
          Length = 479

 Score =  106 bits (264), Expect = 7e-23
 Identities = 58/163 (35%), Positives = 86/163 (52%), Gaps = 15/163 (9%)

Query: 190 VVAGRQACRWVDCCAAYEQQEELVRHIEKSHIDQRKGEDFTCFWAGCVRRYKPFNARYKL 249
           V  G + C+  +C  ++ +  EL RH +++H  ++  E        C    K F    +L
Sbjct: 332 VHTGEKPCKCKECGKSFRRGSELTRH-QRAHTGEKPYE--------CKECEKAFTCSTEL 382

Query: 250 LIHMRVHSGEKPNKCMFEGCSKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDR 309
           + H +VH+GE+P+KC  + C KAF R   L  H RSHTGEKPY C+   C K F   S+ 
Sbjct: 383 VRHQKVHTGERPHKC--KECGKAFIRRSELTHHERSHTGEKPYECKE--CGKPFGGGSEL 438

Query: 310 AKHQRTHLDTKPYACQIPGCSKRYTDPSSLRKHVKAHSAKEQQ 352
           ++HQ+ H   KPY CQ   C K +   S L +H + HS +  +
Sbjct: 439 SRHQKIHTGEKPYECQ--QCGKAFIRASHLSQHQRIHSGQRSE 479



 Score = 79.3 bits (194), Expect = 9e-15
 Identities = 60/217 (27%), Positives = 91/217 (41%), Gaps = 43/217 (19%)

Query: 189 RVVAGRQACRWVDCCAAYEQQEELVRHIEKSHIDQRKGEDFTCFWAGCVRRYKPFNARYK 248
           R+  G +  +  +C  A+    +L  H ++ H D++  E        C    K F     
Sbjct: 191 RMHLGEKPYKCRECGKAFPSTAQLNLH-QRIHTDEKYYE--------CKECGKAFTRPSH 241

Query: 249 LLIHMRVHSGEKPNKCMFEG--------------------------CSKAFSRLENLKIH 282
           L  H R+H+GEKP+KC   G                          C K +S    L +H
Sbjct: 242 LFRHQRIHTGEKPHKCKECGKAFRYDTQLSLHQIIHTGERRYECRECGKVYSCASQLSLH 301

Query: 283 LRSHTGEKPYLCQHPGCQKAFSNSSDRAKHQRTHLDTKPYACQIPGCSKRYTDPSSLRKH 342
            R HTGEKP+ C+   C KAF + S   +HQ  H   KP  C+   C K +   S L +H
Sbjct: 302 QRIHTGEKPHECKE--CGKAFISDSHLIRHQSVHTGEKP--CKCKECGKSFRRGSELTRH 357

Query: 343 VKAHSAKEQQVRKKLHAGPDTEADVLTECLVLQQLHT 379
            +AH+ ++    K+     +      TE +  Q++HT
Sbjct: 358 QRAHTGEKPYECKEC----EKAFTCSTELVRHQKVHT 390



 Score = 75.1 bits (183), Expect = 2e-13
 Identities = 47/158 (29%), Positives = 80/158 (50%), Gaps = 15/158 (9%)

Query: 193 GRQACRWVDCCAAYEQQEELVRHIEKSHIDQRKGEDFTCFWAGCVRRYKPFNARYKLLIH 252
           G +  +  +C  A+    ++ +H ++ H+ ++    + C   G     K F +  +L +H
Sbjct: 167 GEKPHKCKECGKAFRSSSQISQH-QRMHLGEKP---YKCRECG-----KAFPSTAQLNLH 217

Query: 253 MRVHSGEKPNKCMFEGCSKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDRAKH 312
            R+H+ EK  +C  + C KAF+R  +L  H R HTGEKP+ C+   C KAF   +  + H
Sbjct: 218 QRIHTDEKYYEC--KECGKAFTRPSHLFRHQRIHTGEKPHKCKE--CGKAFRYDTQLSLH 273

Query: 313 QRTHLDTKPYACQIPGCSKRYTDPSSLRKHVKAHSAKE 350
           Q  H   + Y C+   C K Y+  S L  H + H+ ++
Sbjct: 274 QIIHTGERRYECR--ECGKVYSCASQLSLHQRIHTGEK 309



 Score = 66.2 bits (160), Expect = 8e-11
 Identities = 48/158 (30%), Positives = 73/158 (46%), Gaps = 23/158 (14%)

Query: 193 GRQACRWVDCCAAYEQQEELVRHIEKSHIDQRKGEDFTCFWAGCVRRYKPFNARYKLLIH 252
           G ++C    C  A+  Q   ++H E  H  +++ E        C    K FN+   L+ H
Sbjct: 85  GEKSCECRKCKNAFRYQSCPIQH-EIIHNKEKEPE--------CGECRKIFNSGSDLIKH 135

Query: 253 MRVHSGEKP---NKCMFEGCSKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDR 309
             +H  +K    NKC       AF+    +      +TGEKP+ C+   C KAF +SS  
Sbjct: 136 QTLHESKKHSENNKC-------AFNHDSGITQPQSINTGEKPHKCKE--CGKAFRSSSQI 186

Query: 310 AKHQRTHLDTKPYACQIPGCSKRYTDPSSLRKHVKAHS 347
           ++HQR HL  KPY C+   C K +   + L  H + H+
Sbjct: 187 SQHQRMHLGEKPYKCR--ECGKAFPSTAQLNLHQRIHT 222



 Score = 35.0 bits (79), Expect = 0.21
 Identities = 23/71 (32%), Positives = 30/71 (42%), Gaps = 4/71 (5%)

Query: 286 HTGEKPYLCQHPGCQKAFSNSSDRAKHQRTHLDTKPYACQIPGCSKRYTDPSSLRKHVKA 345
           HTGEK   C+   C+ AF   S   +H+  H   K   C    C K +   S L KH   
Sbjct: 83  HTGEKSCECRK--CKNAFRYQSCPIQHEIIHNKEKEPECG--ECRKIFNSGSDLIKHQTL 138

Query: 346 HSAKEQQVRKK 356
           H +K+     K
Sbjct: 139 HESKKHSENNK 149


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.135    0.429 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,180,742
Number of Sequences: 37866
Number of extensions: 2259090
Number of successful extensions: 54424
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1272
Number of HSP's successfully gapped in prelim test: 950
Number of HSP's that attempted gapping in prelim test: 13110
Number of HSP's gapped (non-prelim): 14567
length of query: 620
length of database: 18,247,518
effective HSP length: 108
effective length of query: 512
effective length of database: 14,157,990
effective search space: 7248890880
effective search space used: 7248890880
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.