Search of human proteins with 164607133

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|164607133 fer-1-like 5 isoform 2 [Homo sapiens]
         (2093 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|164607133 fer-1-like 5 isoform 2 [Homo sapiens]                   4380   0.0  
gi|116642865 fer-1-like 5 isoform 1 [Homo sapiens]                   1686   0.0  
gi|7305053 myoferlin isoform a [Homo sapiens]                        1528   0.0  
gi|19718759 myoferlin isoform b [Homo sapiens]                       1526   0.0  
gi|195976821 dysferlin isoform 2 [Homo sapiens]                      1441   0.0  
gi|195976777 dysferlin isoform 3 [Homo sapiens]                      1439   0.0  
gi|195976769 dysferlin isoform 6 [Homo sapiens]                      1438   0.0  
gi|195976773 dysferlin isoform 5 [Homo sapiens]                      1437   0.0  
gi|4503431 dysferlin isoform 8 [Homo sapiens]                        1436   0.0  
gi|195976754 dysferlin isoform 9 [Homo sapiens]                      1435   0.0  
gi|195976758 dysferlin isoform 11 [Homo sapiens]                     1434   0.0  
gi|195976756 dysferlin isoform 10 [Homo sapiens]                     1432   0.0  
gi|195976766 dysferlin isoform 7 [Homo sapiens]                      1401   0.0  
gi|195976760 dysferlin isoform 12 [Homo sapiens]                     1401   0.0  
gi|195976775 dysferlin isoform 4 [Homo sapiens]                      1400   0.0  
gi|195976762 dysferlin isoform 13 [Homo sapiens]                     1400   0.0  
gi|195976779 dysferlin isoform 1 [Homo sapiens]                      1398   0.0  
gi|195976764 dysferlin isoform 14 [Homo sapiens]                     1398   0.0  
gi|35493853 otoferlin isoform c [Homo sapiens]                        421   e-117
gi|35493868 otoferlin isoform b [Homo sapiens]                        421   e-117
gi|34740331 otoferlin isoform a [Homo sapiens]                        421   e-117
gi|119120884 fer-1-like 6 [Homo sapiens]                              418   e-116
gi|35493860 otoferlin isoform d [Homo sapiens]                        414   e-115
gi|28376627 synaptotagmin IX [Homo sapiens]                            49   5e-05
gi|238550198 synaptotagmin III [Homo sapiens]                          49   7e-05
gi|238550196 synaptotagmin III [Homo sapiens]                          49   7e-05
gi|14150054 synaptotagmin III [Homo sapiens]                           49   7e-05
gi|103472031 family with sequence similarity 62 (C2 domain conta...    45   0.001
gi|209447073 synaptotagmin I [Homo sapiens]                            44   0.001
gi|5032139 synaptotagmin I [Homo sapiens]                              44   0.001

>gi|164607133 fer-1-like 5 isoform 2 [Homo sapiens]
          Length = 2093

 Score = 4380 bits (11359), Expect = 0.0
 Identities = 2093/2093 (100%), Positives = 2093/2093 (100%)

Query: 1    MLRLVVQSAKIDPPLAPLPRPCMSIDFRDIKKRTRVVEGNDPVWNETLIWHLWNRPLEND 60
            MLRLVVQSAKIDPPLAPLPRPCMSIDFRDIKKRTRVVEGNDPVWNETLIWHLWNRPLEND
Sbjct: 1    MLRLVVQSAKIDPPLAPLPRPCMSIDFRDIKKRTRVVEGNDPVWNETLIWHLWNRPLEND 60

Query: 61   SFLQVTLQDMGSQKKERFIGLATVLLKPLLKQPSEVLFVKDLTLLNHSMKPTDCTVTLQV 120
            SFLQVTLQDMGSQKKERFIGLATVLLKPLLKQPSEVLFVKDLTLLNHSMKPTDCTVTLQV
Sbjct: 61   SFLQVTLQDMGSQKKERFIGLATVLLKPLLKQPSEVLFVKDLTLLNHSMKPTDCTVTLQV 120

Query: 121  AHMSNQDIEKTGAEDHLGITAREAASQKLMVPGSTAHRALSSKPQHFQVRVKVFEARQLM 180
            AHMSNQDIEKTGAEDHLGITAREAASQKLMVPGSTAHRALSSKPQHFQVRVKVFEARQLM
Sbjct: 121  AHMSNQDIEKTGAEDHLGITAREAASQKLMVPGSTAHRALSSKPQHFQVRVKVFEARQLM 180

Query: 181  GNNIKPVVKVSIAGQQHQTRIKMGNNPFFNEIFFQNFHEVPAKFFDETILIQTDIGFIYH 240
            GNNIKPVVKVSIAGQQHQTRIKMGNNPFFNEIFFQNFHEVPAKFFDETILIQTDIGFIYH
Sbjct: 181  GNNIKPVVKVSIAGQQHQTRIKMGNNPFFNEIFFQNFHEVPAKFFDETILIQTDIGFIYH 240

Query: 241  SPGHTLLRKWLGLCQPNNPGSGVTGYLKVTIYALGVGDQALIDQKLLYGTDDTDIQIFKS 300
            SPGHTLLRKWLGLCQPNNPGSGVTGYLKVTIYALGVGDQALIDQKLLYGTDDTDIQIFKS
Sbjct: 241  SPGHTLLRKWLGLCQPNNPGSGVTGYLKVTIYALGVGDQALIDQKLLYGTDDTDIQIFKS 300

Query: 301  AVVPINMAYLQLFIYCAEDLHLKKHQSVNPQLEVELIGEKLRTHMQTQTDNPIWNQILTF 360
            AVVPINMAYLQLFIYCAEDLHLKKHQSVNPQLEVELIGEKLRTHMQTQTDNPIWNQILTF
Sbjct: 301  AVVPINMAYLQLFIYCAEDLHLKKHQSVNPQLEVELIGEKLRTHMQTQTDNPIWNQILTF 360

Query: 361  RIQLPCLSSYIKFRVLDCRKKDCPDEIGTASLSLNQISSTGEEIEGKQSLEPTSYTPRVY 420
            RIQLPCLSSYIKFRVLDCRKKDCPDEIGTASLSLNQISSTGEEIEGKQSLEPTSYTPRVY
Sbjct: 361  RIQLPCLSSYIKFRVLDCRKKDCPDEIGTASLSLNQISSTGEEIEGKQSLEPTSYTPRVY 420

Query: 421  SGFLPCFGPSFLTLHGGKKAPFRIQEEGACIPDSVRDGLAYRGRVFLELITQIKSYQDST 480
            SGFLPCFGPSFLTLHGGKKAPFRIQEEGACIPDSVRDGLAYRGRVFLELITQIKSYQDST
Sbjct: 421  SGFLPCFGPSFLTLHGGKKAPFRIQEEGACIPDSVRDGLAYRGRVFLELITQIKSYQDST 480

Query: 481  IKDLSHEVTRIEKHQNRQKYGLCVIFLSCTMMPNFKELIHFEVSIGHYGNKMDLNYKPLV 540
            IKDLSHEVTRIEKHQNRQKYGLCVIFLSCTMMPNFKELIHFEVSIGHYGNKMDLNYKPLV
Sbjct: 481  IKDLSHEVTRIEKHQNRQKYGLCVIFLSCTMMPNFKELIHFEVSIGHYGNKMDLNYKPLV 540

Query: 541  SSTPYSPVIYDGNIYHYVPWYNTKPVVAVTSNWEDVSFRMNCLNLLHFTRDRLKANLDTL 600
            SSTPYSPVIYDGNIYHYVPWYNTKPVVAVTSNWEDVSFRMNCLNLLHFTRDRLKANLDTL
Sbjct: 541  SSTPYSPVIYDGNIYHYVPWYNTKPVVAVTSNWEDVSFRMNCLNLLHFTRDRLKANLDTL 600

Query: 601  KSTRNPKDPALLYQWEKLLRELAEDCKRPLPCMTYQPKATSLDRKRWQLRSLLLQELAQK 660
            KSTRNPKDPALLYQWEKLLRELAEDCKRPLPCMTYQPKATSLDRKRWQLRSLLLQELAQK
Sbjct: 601  KSTRNPKDPALLYQWEKLLRELAEDCKRPLPCMTYQPKATSLDRKRWQLRSLLLQELAQK 660

Query: 661  AKQAKPKDMVATAEDWLYRLNTVLPEPQMGLPDVMIWLVAKEQRVAYAQVPAHSVLFSPA 720
            AKQAKPKDMVATAEDWLYRLNTVLPEPQMGLPDVMIWLVAKEQRVAYAQVPAHSVLFSPA
Sbjct: 661  AKQAKPKDMVATAEDWLYRLNTVLPEPQMGLPDVMIWLVAKEQRVAYAQVPAHSVLFSPA 720

Query: 721  GALHSGRLCGKIQTLFLQYPEGEGQKDVLPAHLRVCMWLGNVTDSKDLQLLRQGDTAVYA 780
            GALHSGRLCGKIQTLFLQYPEGEGQKDVLPAHLRVCMWLGNVTDSKDLQLLRQGDTAVYA
Sbjct: 721  GALHSGRLCGKIQTLFLQYPEGEGQKDVLPAHLRVCMWLGNVTDSKDLQLLRQGDTAVYA 780

Query: 781  EMYENQAKYKDQWGQQGLYHCPNFSDVMGNKTLPMTDFQPPLGWHWQDSWTVEPQRRLLL 840
            EMYENQAKYKDQWGQQGLYHCPNFSDVMGNKTLPMTDFQPPLGWHWQDSWTVEPQRRLLL
Sbjct: 781  EMYENQAKYKDQWGQQGLYHCPNFSDVMGNKTLPMTDFQPPLGWHWQDSWTVEPQRRLLL 840

Query: 841  DIDINKSQVLEEVYENQGRDTRGAWGPAAIPNTDVNGQPMEARENVKCPQGWHFKKDWVV 900
            DIDINKSQVLEEVYENQGRDTRGAWGPAAIPNTDVNGQPMEARENVKCPQGWHFKKDWVV
Sbjct: 841  DIDINKSQVLEEVYENQGRDTRGAWGPAAIPNTDVNGQPMEARENVKCPQGWHFKKDWVV 900

Query: 901  ELNHAVDSWEYGVGIPPSGLPQVWSPVEKTYHSCRRRRWARVRFRNHGELSHEQETLSFL 960
            ELNHAVDSWEYGVGIPPSGLPQVWSPVEKTYHSCRRRRWARVRFRNHGELSHEQETLSFL
Sbjct: 901  ELNHAVDSWEYGVGIPPSGLPQVWSPVEKTYHSCRRRRWARVRFRNHGELSHEQETLSFL 960

Query: 961  QLGLAKGEEEGWEYDTFGSKFHLNPQPQSRFRRRCWRRRLAPNKDKGIAPIFLLEGSLAC 1020
            QLGLAKGEEEGWEYDTFGSKFHLNPQPQSRFRRRCWRRRLAPNKDKGIAPIFLLEGSLAC
Sbjct: 961  QLGLAKGEEEGWEYDTFGSKFHLNPQPQSRFRRRCWRRRLAPNKDKGIAPIFLLEGSLAC 1020

Query: 1021 EGGSVREEGDWAWARGNRSSTQEPQGRLSWVQAMDLKYHAGKEEDSKTWPWGLDRQFRDP 1080
            EGGSVREEGDWAWARGNRSSTQEPQGRLSWVQAMDLKYHAGKEEDSKTWPWGLDRQFRDP
Sbjct: 1021 EGGSVREEGDWAWARGNRSSTQEPQGRLSWVQAMDLKYHAGKEEDSKTWPWGLDRQFRDP 1080

Query: 1081 QRQDTRPPNLPFIYCTFNKPHYYQLFCYIYQARNLVSNQILTFQGPFIRVVFLNHSQCTQ 1140
            QRQDTRPPNLPFIYCTFNKPHYYQLFCYIYQARNLVSNQILTFQGPFIRVVFLNHSQCTQ
Sbjct: 1081 QRQDTRPPNLPFIYCTFNKPHYYQLFCYIYQARNLVSNQILTFQGPFIRVVFLNHSQCTQ 1140

Query: 1141 TLRSSAGPTWAQTLIFQHLLLYENPQDTKESPPLVVLELWQRDFWGKESLWGRSVWPPMV 1200
            TLRSSAGPTWAQTLIFQHLLLYENPQDTKESPPLVVLELWQRDFWGKESLWGRSVWPPMV
Sbjct: 1141 TLRSSAGPTWAQTLIFQHLLLYENPQDTKESPPLVVLELWQRDFWGKESLWGRSVWPPMV 1200

Query: 1201 WLDLQDRILPPMRWHPLVKELGKEEGEILASCELILQTEKLGEKQLPILSVPWKNGAYTL 1260
            WLDLQDRILPPMRWHPLVKELGKEEGEILASCELILQTEKLGEKQLPILSVPWKNGAYTL
Sbjct: 1201 WLDLQDRILPPMRWHPLVKELGKEEGEILASCELILQTEKLGEKQLPILSVPWKNGAYTL 1260

Query: 1261 PKSIQPTIKRMAIEILAWGLRNMKKASSPQLLVEFGEESLRTEPIRDFQTNPNFPESESV 1320
            PKSIQPTIKRMAIEILAWGLRNMKKASSPQLLVEFGEESLRTEPIRDFQTNPNFPESESV
Sbjct: 1261 PKSIQPTIKRMAIEILAWGLRNMKKASSPQLLVEFGEESLRTEPIRDFQTNPNFPESESV 1320

Query: 1321 LVLTVLMPTEEAYALPLVVKVVDNWAFGQQTVTGQANIDFLQPYFCDPWAQDYMHPKLPT 1380
            LVLTVLMPTEEAYALPLVVKVVDNWAFGQQTVTGQANIDFLQPYFCDPWAQDYMHPKLPT
Sbjct: 1321 LVLTVLMPTEEAYALPLVVKVVDNWAFGQQTVTGQANIDFLQPYFCDPWAQDYMHPKLPT 1380

Query: 1381 LSEKKHQDFLGYLYRKFWFKSSKAEDEYEHEVDWWSKLFWATDEHKSLKYKYKDYHTLKV 1440
            LSEKKHQDFLGYLYRKFWFKSSKAEDEYEHEVDWWSKLFWATDEHKSLKYKYKDYHTLKV
Sbjct: 1381 LSEKKHQDFLGYLYRKFWFKSSKAEDEYEHEVDWWSKLFWATDEHKSLKYKYKDYHTLKV 1440

Query: 1441 YECELEAVPAFQGLQDFCQTFKLYQEQPKLDSPVVGEFKGLFRIYPFPENPEAPKPPLQF 1500
            YECELEAVPAFQGLQDFCQTFKLYQEQPKLDSPVVGEFKGLFRIYPFPENPEAPKPPLQF
Sbjct: 1441 YECELEAVPAFQGLQDFCQTFKLYQEQPKLDSPVVGEFKGLFRIYPFPENPEAPKPPLQF 1500

Query: 1501 LVWPEREDFPQPCLVRVYMVRAINLQPQDYNGLCDPYVILKLGKTELGNRDMYQPNTLDP 1560
            LVWPEREDFPQPCLVRVYMVRAINLQPQDYNGLCDPYVILKLGKTELGNRDMYQPNTLDP
Sbjct: 1501 LVWPEREDFPQPCLVRVYMVRAINLQPQDYNGLCDPYVILKLGKTELGNRDMYQPNTLDP 1560

Query: 1561 IFGMMFELTCNIPLEKDLEIQLYDFDLFSPDDKIGTTVIDLENRLLSGFGAHCGLSKSYC 1620
            IFGMMFELTCNIPLEKDLEIQLYDFDLFSPDDKIGTTVIDLENRLLSGFGAHCGLSKSYC
Sbjct: 1561 IFGMMFELTCNIPLEKDLEIQLYDFDLFSPDDKIGTTVIDLENRLLSGFGAHCGLSKSYC 1620

Query: 1621 QSGPFRWRDQMPPSYLLERYAKRKGLPPPLFSPEEDAVFYNGKKFKLQSFEPKTPTVHGL 1680
            QSGPFRWRDQMPPSYLLERYAKRKGLPPPLFSPEEDAVFYNGKKFKLQSFEPKTPTVHGL
Sbjct: 1621 QSGPFRWRDQMPPSYLLERYAKRKGLPPPLFSPEEDAVFYNGKKFKLQSFEPKTPTVHGL 1680

Query: 1681 GPKKERLALYLLHTQGLVPEHVETRTLYSHSQPGIDQGKVQMWVDIFPKKLGPPGPQVNI 1740
            GPKKERLALYLLHTQGLVPEHVETRTLYSHSQPGIDQGKVQMWVDIFPKKLGPPGPQVNI
Sbjct: 1681 GPKKERLALYLLHTQGLVPEHVETRTLYSHSQPGIDQGKVQMWVDIFPKKLGPPGPQVNI 1740

Query: 1741 NPRKPKRKASEHSGHRYELRCIIWKTANVDLVDDNLSREKTSDIYIKGWLYGLEKDMQKT 1800
            NPRKPKRKASEHSGHRYELRCIIWKTANVDLVDDNLSREKTSDIYIKGWLYGLEKDMQKT
Sbjct: 1741 NPRKPKRKASEHSGHRYELRCIIWKTANVDLVDDNLSREKTSDIYIKGWLYGLEKDMQKT 1800

Query: 1801 DIHYHSLTGEADFNWRFIFTMDYLAAERTCVQSQKDYIWSLDATSMKFPARLIIQVWDND 1860
            DIHYHSLTGEADFNWRFIFTMDYLAAERTCVQSQKDYIWSLDATSMKFPARLIIQVWDND
Sbjct: 1801 DIHYHSLTGEADFNWRFIFTMDYLAAERTCVQSQKDYIWSLDATSMKFPARLIIQVWDND 1860

Query: 1861 IFSPDDFLGVLELDLSDMPLPARHAKQCSIRMMDADPKWPYFIQYKHFSLFKKKTVTGWW 1920
            IFSPDDFLGVLELDLSDMPLPARHAKQCSIRMMDADPKWPYFIQYKHFSLFKKKTVTGWW
Sbjct: 1861 IFSPDDFLGVLELDLSDMPLPARHAKQCSIRMMDADPKWPYFIQYKHFSLFKKKTVTGWW 1920

Query: 1921 PCQVLDGGKWRLSGKVKMSLEILSEKEALIKPAGRGQSEPNQYPTLHPPLRTNTSFTWLR 1980
            PCQVLDGGKWRLSGKVKMSLEILSEKEALIKPAGRGQSEPNQYPTLHPPLRTNTSFTWLR
Sbjct: 1921 PCQVLDGGKWRLSGKVKMSLEILSEKEALIKPAGRGQSEPNQYPTLHPPLRTNTSFTWLR 1980

Query: 1981 SPVQNFCYIFWKRYRFKLIAFMVISIIALMLFNFIYSAPHYLAMSWIKPQLQLYPPIKIF 2040
            SPVQNFCYIFWKRYRFKLIAFMVISIIALMLFNFIYSAPHYLAMSWIKPQLQLYPPIKIF
Sbjct: 1981 SPVQNFCYIFWKRYRFKLIAFMVISIIALMLFNFIYSAPHYLAMSWIKPQLQLYPPIKIF 2040

Query: 2041 NIINSLNTSNASSSILPTQDPNLKPTIDHEWKLHPGPTNHLSDIFPELPAPGD 2093
            NIINSLNTSNASSSILPTQDPNLKPTIDHEWKLHPGPTNHLSDIFPELPAPGD
Sbjct: 2041 NIINSLNTSNASSSILPTQDPNLKPTIDHEWKLHPGPTNHLSDIFPELPAPGD 2093


>gi|116642865 fer-1-like 5 isoform 1 [Homo sapiens]
          Length = 802

 Score = 1686 bits (4365), Expect = 0.0
 Identities = 802/811 (98%), Positives = 802/811 (98%), Gaps = 9/811 (1%)

Query: 1283 MKKASSPQLLVEFGEESLRTEPIRDFQTNPNFPESESVLVLTVLMPTEEAYALPLVVKVV 1342
            MKKASSPQLLVEFGEESLRTEPIRDFQTNPNFPESESVLVLTVLMPTEEAYALPLVVKVV
Sbjct: 1    MKKASSPQLLVEFGEESLRTEPIRDFQTNPNFPESESVLVLTVLMPTEEAYALPLVVKVV 60

Query: 1343 DNWAFGQQTVTGQANIDFLQPYFCDPWAQDYMHPKLPTLSEKKHQDFLGYLYRKFWFKSS 1402
            DNWAFGQQTVTGQANIDFLQPYFCDPWAQDYMHPKLPTLSEKKHQDFLGYLYRKFWFKSS
Sbjct: 61   DNWAFGQQTVTGQANIDFLQPYFCDPWAQDYMHPKLPTLSEKKHQDFLGYLYRKFWFKSS 120

Query: 1403 KAEDEYEHEVDWWSKLFWATDEHKSLKYKYKDYHTLKVYECELEAVPAFQGLQDFCQTFK 1462
            KAEDEYEHEVDWWSKLFWATDEHKSLKYKYKDYHTLKVYECELEAVPAFQGLQDFCQTFK
Sbjct: 121  KAEDEYEHEVDWWSKLFWATDEHKSLKYKYKDYHTLKVYECELEAVPAFQGLQDFCQTFK 180

Query: 1463 LYQEQPKLDSPVVGEFKGLFRIYPFPENPEAPKPPLQFLVWPEREDFPQPCLVRVYMVRA 1522
            LYQEQPKLDSPVVGEFKGLFRIYPFPENPEAPKPPLQFLVWPEREDFPQPCLVRVYMVRA
Sbjct: 181  LYQEQPKLDSPVVGEFKGLFRIYPFPENPEAPKPPLQFLVWPEREDFPQPCLVRVYMVRA 240

Query: 1523 INLQPQDYNGLCDPYVILKLGKTELGNRDMYQPNTLDPIFGMMFELTCNIPLEKDLEIQL 1582
            INLQPQDYNGLCDPYVILKLGKTELGNRDMYQPNTLDPIFGMMFELTCNIPLEKDLEIQL
Sbjct: 241  INLQPQDYNGLCDPYVILKLGKTELGNRDMYQPNTLDPIFGMMFELTCNIPLEKDLEIQL 300

Query: 1583 YDFDLFSPDDKIGTTVIDLENRLLSGFGAHCGLSKSYCQSGPFRWRDQMPPSYLLERYAK 1642
            YDFDLFSPDDKIGTTVIDLENRLLSGFGAHCGLSKSYCQSGPFRWRDQMPPSYLLERYAK
Sbjct: 301  YDFDLFSPDDKIGTTVIDLENRLLSGFGAHCGLSKSYCQSGPFRWRDQMPPSYLLERYAK 360

Query: 1643 RKGLPPPLFSPEEDAVFYNGKKFKLQSFEPKTPTVHGLGPKKERLALYLLHTQGLVPEHV 1702
            RKGLPPPLFSPEEDAVFYNGKKFKLQSFEPKTPTVHGLGPKKERLALYLLHTQGLVPEHV
Sbjct: 361  RKGLPPPLFSPEEDAVFYNGKKFKLQSFEPKTPTVHGLGPKKERLALYLLHTQGLVPEHV 420

Query: 1703 ETRTLYSHSQPGIDQGKVQMWVDIFPKKLGPPGPQVNINPRKPKRKASEHSGHRYELRCI 1762
            ETRTLYSHSQPGIDQGKVQMWVDIFPKKLGPPGPQVNINPRKPK         RYELRCI
Sbjct: 421  ETRTLYSHSQPGIDQGKVQMWVDIFPKKLGPPGPQVNINPRKPK---------RYELRCI 471

Query: 1763 IWKTANVDLVDDNLSREKTSDIYIKGWLYGLEKDMQKTDIHYHSLTGEADFNWRFIFTMD 1822
            IWKTANVDLVDDNLSREKTSDIYIKGWLYGLEKDMQKTDIHYHSLTGEADFNWRFIFTMD
Sbjct: 472  IWKTANVDLVDDNLSREKTSDIYIKGWLYGLEKDMQKTDIHYHSLTGEADFNWRFIFTMD 531

Query: 1823 YLAAERTCVQSQKDYIWSLDATSMKFPARLIIQVWDNDIFSPDDFLGVLELDLSDMPLPA 1882
            YLAAERTCVQSQKDYIWSLDATSMKFPARLIIQVWDNDIFSPDDFLGVLELDLSDMPLPA
Sbjct: 532  YLAAERTCVQSQKDYIWSLDATSMKFPARLIIQVWDNDIFSPDDFLGVLELDLSDMPLPA 591

Query: 1883 RHAKQCSIRMMDADPKWPYFIQYKHFSLFKKKTVTGWWPCQVLDGGKWRLSGKVKMSLEI 1942
            RHAKQCSIRMMDADPKWPYFIQYKHFSLFKKKTVTGWWPCQVLDGGKWRLSGKVKMSLEI
Sbjct: 592  RHAKQCSIRMMDADPKWPYFIQYKHFSLFKKKTVTGWWPCQVLDGGKWRLSGKVKMSLEI 651

Query: 1943 LSEKEALIKPAGRGQSEPNQYPTLHPPLRTNTSFTWLRSPVQNFCYIFWKRYRFKLIAFM 2002
            LSEKEALIKPAGRGQSEPNQYPTLHPPLRTNTSFTWLRSPVQNFCYIFWKRYRFKLIAFM
Sbjct: 652  LSEKEALIKPAGRGQSEPNQYPTLHPPLRTNTSFTWLRSPVQNFCYIFWKRYRFKLIAFM 711

Query: 2003 VISIIALMLFNFIYSAPHYLAMSWIKPQLQLYPPIKIFNIINSLNTSNASSSILPTQDPN 2062
            VISIIALMLFNFIYSAPHYLAMSWIKPQLQLYPPIKIFNIINSLNTSNASSSILPTQDPN
Sbjct: 712  VISIIALMLFNFIYSAPHYLAMSWIKPQLQLYPPIKIFNIINSLNTSNASSSILPTQDPN 771

Query: 2063 LKPTIDHEWKLHPGPTNHLSDIFPELPAPGD 2093
            LKPTIDHEWKLHPGPTNHLSDIFPELPAPGD
Sbjct: 772  LKPTIDHEWKLHPGPTNHLSDIFPELPAPGD 802


>gi|7305053 myoferlin isoform a [Homo sapiens]
          Length = 2061

 Score = 1528 bits (3957), Expect = 0.0
 Identities = 852/2128 (40%), Positives = 1222/2128 (57%), Gaps = 164/2128 (7%)

Query: 1    MLRLVVQSAKIDPPLA-PLPRPCMSIDFRDIKKRTRVVEGN-DPVWNETLIWHLWNRPLE 58
            MLR++V+SA   P      P P +S+ F+D KK+T+ V+   +PVWNE L + L   PL+
Sbjct: 1    MLRVIVESASNIPKTKFGKPDPIVSVIFKDEKKKTKKVDNELNPVWNEILEFDLRGIPLD 60

Query: 59   NDSFLQVTLQDMGSQKKERFIGLATVLLKPLLKQPSEVLFVKDLTLLNHSMKPTDCTVTL 118
              S L + ++D  +  + + IG ATV LK L    S  L  K ++LLN   + T  T+ L
Sbjct: 61   FSSSLGIIVKDFETIGQNKLIGTATVALKDLTGDQSRSLPYKLISLLNEKGQDTGATIDL 120

Query: 119  QVAH------------------MSNQDIEKTGAEDHLGITAR------------EAASQK 148
             + +                  M     E  G ED L    R            EA   +
Sbjct: 121  VIGYDPPSAPHPNDLSGPSVPGMGGDGEEDEGDEDRLDNAVRGPGPKGPVGTVSEAQLAR 180

Query: 149  LMVPGSTAHRALSSKPQHFQVRVKVFEARQLMGNNIKPVVKVSIAGQQHQTRIKMGNNPF 208
             +     + R LS+KPQ FQ+RV+V E RQL GNNI+PVVKV + GQ H+TRIK GNNPF
Sbjct: 181  RLTKVKNSRRMLSNKPQDFQIRVRVIEGRQLSGNNIRPVVKVHVCGQTHRTRIKRGNNPF 240

Query: 209  FNEIFFQNFHEVPAKFFDETILIQT-----------------DIGFIYHSPGHTLLRKWL 251
            F+E+FF N +  P++  DE I I+                  D+GF+Y  PGH ++RKWL
Sbjct: 241  FDELFFYNVNMTPSELMDEIISIRVYNSHSLRADCLMGEFKIDVGFVYDEPGHAVMRKWL 300

Query: 252  GLCQPNNPGSGVTGYLKVTIYALGVGDQALIDQKLLYG-TDDTDIQIFKSAVVPINMAYL 310
             L  P +  SG  GY+KV+++ LG GD+   +++     +DD +  +   A + +     
Sbjct: 301  LLNDPEDTSSGSKGYMKVSMFVLGTGDEPPPERRDRDNDSDDVESNLLLPAGIALRWVTF 360

Query: 311  QLFIYCAEDL-----------------HLKKHQSVNPQLEVELIGEKLRTHMQTQTDNPI 353
             L IY AED+                 +  K   V+P +EV   G+K+ T++  +  NP 
Sbjct: 361  LLKIYRAEDIPQMDDAFSQTVKEIFGGNADKKNLVDPFVEVSFAGKKVCTNIIEKNANPE 420

Query: 354  WNQILTFRIQLPCLSSYIKFRVLDCRKKDCPDEIGTASLSLNQISSTGEEIE-----GKQ 408
            WNQ++  +I+ P +   IK  + D  +    D +GT  L L++I+++G E+E     G  
Sbjct: 421  WNQVVNLQIKFPSVCEKIKLTIYDWDRLTKNDVVGTTYLHLSKIAASGGEVEDFSSSGTG 480

Query: 409  SLEPTSYTPRVYSGFLPCFGPSFLTLHGGKKAPFRIQEEGACIPDSVRDGLAYRGRVFLE 468
            +   T  T     GF+P FGP +L L+G  +      +    +     +G+AYRGR+ +E
Sbjct: 481  AASYTVNTGETEVGFVPTFGPCYLNLYGSPREYTGFPDPYDELNTGKGEGVAYRGRILVE 540

Query: 469  LITQI-KSYQDSTIKDLSHE-VTRIEKHQNRQKYGLCVIFLSCTMMPNFKELIHFEVSIG 526
            L T + K+  D  ++ +S++ +  +EK+Q R+KY L  +F S TM+ +  E I FEVSIG
Sbjct: 541  LATFLEKTPPDKKLEPISNDDLLVVEKYQRRRKYSLSAVFHSATMLQDVGEAIQFEVSIG 600

Query: 527  HYGNKMDLNYKPLVSSTPYSPVIYDGNIYHYVPWYNTKPVVAVTSNWEDVSFRMNCLNLL 586
            +YGNK D   KPL S+T YS  ++DGN Y+Y+PW +TKPVV +TS WED+S R++ +N L
Sbjct: 601  NYGNKFDTTCKPLASTTQYSRAVFDGNYYYYLPWAHTKPVVTLTSYWEDISHRLDAVNTL 660

Query: 587  HFTRDRLKANLDTLKSTRNPKDPA--LLYQWEKLLRELAEDCKRPLPCMTYQPKATSLDR 644
                +RL+ N++ LKS    K PA  L   W KL+ E+ ED +  LP    +   T LD 
Sbjct: 661  LAMAERLQTNIEALKSGIQGKIPANQLAELWLKLIDEVIEDTRYTLPLTEGKANVTVLDT 720

Query: 645  KRWQLRSLLLQELAQKAKQAKP-----KDMVATAEDWLYRLNTVLPEPQMGLPDVMIWLV 699
            +  +LRS  L ++ + A + +      K  +A  EDWL +L  +  EPQ  +PD++IW++
Sbjct: 721  QIRKLRSRSLSQIHEAAVRMRSEATDVKSTLAEIEDWLDKLMQLTEEPQNSMPDIIIWMI 780

Query: 700  AKEQRVAYAQVPAHSVLFSPAGALHSGRLCGKIQTLFLQYPEGEGQKDVLPAHLRVCMWL 759
              E+R+AYA++PAH VL+S +G   SG+ CGK QT+FL+YP+ +     +P  LRV +WL
Sbjct: 781  RGEKRLAYARIPAHQVLYSTSGENASGKYCGKTQTIFLKYPQEKNNGPKVPVELRVNIWL 840

Query: 760  GNVTDSKDLQLLRQGDTAVYAEMYENQAKYKDQWGQQGLYHCPNFSDVMGNKTLPMTDFQ 819
            G     K      +G   V+AEMYENQA    +WG  GL     FSDV G   L    F 
Sbjct: 841  GLSAVEKKFNSFAEGTFTVFAEMYENQALMFGKWGTSGLVGRHKFSDVTGKIKLKREFFL 900

Query: 820  PPLGWHWQDSWTVEPQRRLLLDIDINKSQVLEEVYENQGRDTRGAWGPAAIPNTDVNGQP 879
            PP GW W+  W V+P+R LL + D   ++  +EVY+N+ R   G W PA    TD NG  
Sbjct: 901  PPKGWEWEGEWIVDPERSLLTEADAGHTEFTDEVYQNESRYPGGDWKPAEDTYTDANGDK 960

Query: 880  MEARENVKCPQGWHFKKD-WVVELNHAVDS--WEYGVGIPPSGLPQVWSPVEKTYHSCRR 936
              +   + CP GW ++ D W  ++N AVD   WEYG+ IPP   P+ W   EK YH+ RR
Sbjct: 961  AASPSELTCPPGWEWEDDAWSYDINRAVDEKGWEYGITIPPDHKPKSWVAAEKMYHTHRR 1020

Query: 937  RRWARVRFRNHGEL-SHEQETLSFLQLGLAKGEEEGWEYDTF-GSKFHLNPQPQSRFRRR 994
            RR  R R ++  +  S     +  LQ      ++EGWEY +  G KFH   +    FRRR
Sbjct: 1021 RRLVRKRKKDLTQTASSTARAMEELQ------DQEGWEYASLIGWKFHWKQRSSDTFRRR 1074

Query: 995  CWRRRLAPNKDKGIAPIFLLEGSLACEGGSVREEGDWAWARGNRSSTQEPQGRLSWVQAM 1054
             WRR++AP++  G A IF LEG+L   G    E+GD                        
Sbjct: 1075 RWRRKMAPSETHGAAAIFKLEGAL---GADTTEDGD------------------------ 1107

Query: 1055 DLKYHAGKEEDSKTWPWGLDRQFRDPQRQDTRPPNLPFIYCTFNKPHYYQLFCYIYQARN 1114
              +    K++ S T  +G                N P + C F++ + Y L CY+YQARN
Sbjct: 1108 --EKSLEKQKHSATTVFGA---------------NTPIVSCNFDRVYIYHLRCYVYQARN 1150

Query: 1115 LVSNQILTFQGPFIRVVFLNHSQCTQTLRSSAGPTWAQTLIFQHLLLYENPQDTKESPPL 1174
            L++    +F  P+  + FL+ S+ T+ + S+  PTW QT+IF  + +Y  PQ   ++PP 
Sbjct: 1151 LLALDKDSFSDPYAHICFLHRSKTTEIIHSTLNPTWDQTIIFDEVEIYGEPQTVLQNPPK 1210

Query: 1175 VVLELWQRDFWGKESLWGRSVWPPMVWLDLQDRILPPMRWHPLVKELGKEEGEILASCEL 1234
            V++EL+  D  GK+   GRS++ P+V L+ +  I P + WHP++    K  G++L + EL
Sbjct: 1211 VIMELFDNDQVGKDEFLGRSIFSPVVKLNSEMDITPKLLWHPVMNG-DKACGDVLVTAEL 1269

Query: 1235 ILQTEKLGEKQLPILSVPWKNGAYTLPKSIQPTIKRMAIEILAWGLRNMKK-----ASSP 1289
            IL+ +      LPIL        Y +P+ I+P ++  AIEILAWGLRNMK       +SP
Sbjct: 1270 ILRGKD--GSNLPILPPQRAPNLYMVPQGIRPVVQLTAIEILAWGLRNMKNFQMASITSP 1327

Query: 1290 QLLVEFGEESLRTEPIRDFQTNPNFPESESVLVLTVLMPTEEAYALPLVVKVVDNWAFGQ 1349
             L+VE G E + +  I++ +  PNFP S  VL + V +P EE Y  PLV+KV+D+  FG+
Sbjct: 1328 SLVVECGGERVESVVIKNLKKTPNFPSS--VLFMKVFLPKEELYMPPLVIKVIDHRQFGR 1385

Query: 1350 QTVTGQANIDFLQPYFCDPWA-QDYMHPKLPT--LSEKKHQDFLGYLYRKFWFKSSKAED 1406
            + V GQ  I+ L  + CDP+A ++ + P+L    LS    +D +  +       +SK  +
Sbjct: 1386 KPVVGQCTIERLDRFRCDPYAGKEDIVPQLKASLLSAPPCRDIVIEMEDTKPLLASKLTE 1445

Query: 1407 EYEHEVDWWSKLFWATDEHKSL-KYKYKDYHTLKVYECELEAVPAFQGLQDFCQTFKLYQ 1465
            + E  VDWWSK + ++ EH+   +Y  K Y  LK+Y CELE V  F+GL DF  TFKLY+
Sbjct: 1446 KEEEIVDWWSKFYASSGEHEKCGQYIQKGYSKLKIYNCELENVAEFEGLTDFSDTFKLYR 1505

Query: 1466 --EQPKLDSPVVGEFKGLFRIYPFPENPEAPKPPLQFLVWPEREDFPQPCLVRVYMVRAI 1523
                   D  VVGEFKG FRIYP P++P  P PP QF   P+    PQ C VR+Y+VR +
Sbjct: 1506 GKSDENEDPSVVGEFKGSFRIYPLPDDPSVPAPPRQFRELPD--SVPQECTVRIYIVRGL 1563

Query: 1524 NLQPQDYNGLCDPYVILKLGKTELGNRDMYQPNTLDPIFGMMFELTCNIPLEKDLEIQLY 1583
             LQPQD NGLCDPY+ + LGK  + +RD Y PNTL+P+FG M+EL+C +P EKDL+I +Y
Sbjct: 1564 ELQPQDNNGLCDPYIKITLGKKVIEDRDHYIPNTLNPVFGRMYELSCYLPQEKDLKISVY 1623

Query: 1584 DFDLFSPDDKIGTTVIDLENRLLSGFGAHCGLSKSYCQSGPFRWRDQMPPSYLLERYAKR 1643
            D+D F+ D+K+G T+IDLENR LS FG+HCG+ + YC SG   WRDQ+ P+ LL+  A+ 
Sbjct: 1624 DYDTFTRDEKVGETIIDLENRFLSRFGSHCGIPEEYCVSGVNTWRDQLRPTQLLQNVARF 1683

Query: 1644 KGLPPPLFSPEEDAVFYNGKKFKLQSFEPKTPTVHGLGPKKERLALYLLHTQGLVPEHVE 1703
            KG P P+ S +   + Y G+ + L  FE        LG  +ERLAL++L TQGLVPEHVE
Sbjct: 1684 KGFPQPILSEDGSRIRYGGRDYSLDEFEANKILHQHLGAPEERLALHILRTQGLVPEHVE 1743

Query: 1704 TRTLYSHSQPGIDQGKVQMWVDIFPKKLGPPGPQVNINPRKPKRKASEHSGHRYELRCII 1763
            TRTL+S  QP I QGK+QMWVD+FPK LGPPGP  NI PRK K         +Y LR II
Sbjct: 1744 TRTLHSTFQPNISQGKLQMWVDVFPKSLGPPGPPFNITPRKAK---------KYYLRVII 1794

Query: 1764 WKTANVDLVDDNLSREKTSDIYIKGWLYGLEKDMQKTDIHYHSLTGEADFNWRFIFTMDY 1823
            W T +V L + +++ E+ SDIY+KGW+ G E++ QKTD+HY SL GE +FNWRF+F  DY
Sbjct: 1795 WNTKDVILDEKSITGEEMSDIYVKGWIPGNEENKQKTDVHYRSLDGEGNFNWRFVFPFDY 1854

Query: 1824 LAAERTCVQSQKDYIWSLDATSMKFPARLIIQVWDNDIFSPDDFLGVLELDLSDMPLPAR 1883
            L AE+ C+ ++K++ WS+D T  + P RLIIQ+WDND FS DD+LG LELDL    +PA+
Sbjct: 1855 LPAEQLCIVAKKEHFWSIDQTEFRIPPRLIIQIWDNDKFSLDDYLGFLELDLRHTIIPAK 1914

Query: 1884 HAKQCSIRMMDADPKWPYFIQYKHFSLFKKKTVTGWWPCQVLDGGKWRLSGKVKMSLEIL 1943
              ++C + M+  D K    ++ K  SLF++K++ GWWPC     G   ++GKV+M+LEIL
Sbjct: 1915 SPEKCRLDMI-PDLKAMNPLKAKTASLFEQKSMKGWWPCYAEKDGARVMAGKVEMTLEIL 1973

Query: 1944 SEKEALIKPAGRGQSEPNQYPTLHPPLRTNTSFTWLRSPVQNFCYIFWKRYRFKLIAFMV 2003
            +EKEA  +PAG+G+ EPN  P L  P R  TSF W  +P +   +I W+R+++ +I  + 
Sbjct: 1974 NEKEADERPAGKGRDEPNMNPKLDLPNRPETSFLWFTNPCKTMKFIVWRRFKWVIIGLLF 2033

Query: 2004 ISIIALMLFNFIYSAPHYLAMSWIKPQL 2031
            + I+ L +   +YS P+YL+M  +KP +
Sbjct: 2034 LLILLLFVAVLLYSLPNYLSMKIVKPNV 2061


>gi|19718759 myoferlin isoform b [Homo sapiens]
          Length = 2048

 Score = 1526 bits (3950), Expect = 0.0
 Identities = 850/2123 (40%), Positives = 1219/2123 (57%), Gaps = 167/2123 (7%)

Query: 1    MLRLVVQSAKIDPPLA-PLPRPCMSIDFRDIKKRTRVVEGN-DPVWNETLIWHLWNRPLE 58
            MLR++V+SA   P      P P +S+ F+D KK+T+ V+   +PVWNE L + L   PL+
Sbjct: 1    MLRVIVESASNIPKTKFGKPDPIVSVIFKDEKKKTKKVDNELNPVWNEILEFDLRGIPLD 60

Query: 59   NDSFLQVTLQDMGSQKKERFIGLATVLLKPLLKQPSEVLFVKDLTLLNHSMKPTDCTVTL 118
              S L + ++D  +  + + IG ATV LK L    S  L  K ++LLN   + T  T+ L
Sbjct: 61   FSSSLGIIVKDFETIGQNKLIGTATVALKDLTGDQSRSLPYKLISLLNEKGQDTGATIDL 120

Query: 119  QVAH------------------MSNQDIEKTGAEDHLGITAR------------EAASQK 148
             + +                  M     E  G ED L    R            EA   +
Sbjct: 121  VIGYDPPSAPHPNDLSGPSVPGMGGDGEEDEGDEDRLDNAVRGPGPKGPVGTVSEAQLAR 180

Query: 149  LMVPGSTAHRALSSKPQHFQVRVKVFEARQLMGNNIKPVVKVSIAGQQHQTRIKMGNNPF 208
             +     + R LS+KPQ FQ+RV+V E RQL GNNI+PVVKV + GQ H+TRIK GNNPF
Sbjct: 181  RLTKVKNSRRMLSNKPQDFQIRVRVIEGRQLSGNNIRPVVKVHVCGQTHRTRIKRGNNPF 240

Query: 209  FNEIFFQNFHEVPAKFFDETILIQT-----------------DIGFIYHSPGHTLLRKWL 251
            F+E+FF N +  P++  DE I I+                  D+GF+Y  PGH ++RKWL
Sbjct: 241  FDELFFYNVNMTPSELMDEIISIRVYNSHSLRADCLMGEFKIDVGFVYDEPGHAVMRKWL 300

Query: 252  GLCQPNNPGSGVTGYLKVTIYALGVGDQALIDQKLLYG-TDDTDIQIFKSAVVPINMAYL 310
             L  P +  SG  GY+KV+++ LG GD+   +++     +DD +  +   A + +     
Sbjct: 301  LLNDPEDTSSGSKGYMKVSMFVLGTGDEPPPERRDRDNDSDDVESNLLLPAGIALRWVTF 360

Query: 311  QLFIYCAEDL-----------------HLKKHQSVNPQLEVELIGEKLRTHMQTQTDNPI 353
             L IY AED+                 +  K   V+P +EV   G+K+ T++  +  NP 
Sbjct: 361  LLKIYRAEDIPQMDDAFSQTVKEIFGGNADKKNLVDPFVEVSFAGKKVCTNIIEKNANPE 420

Query: 354  WNQILTFRIQLPCLSSYIKFRVLDCRKKDCPDEIGTASLSLNQISSTGEEIEGKQSLEPT 413
            WNQ++  +I+ P +   IK  + D  +    D +GT  L L++I+++G E+E        
Sbjct: 421  WNQVVNLQIKFPSVCEKIKLTIYDWDRLTKNDVVGTTYLHLSKIAASGGEVEVN------ 474

Query: 414  SYTPRVYSGFLPCFGPSFLTLHGGKKAPFRIQEEGACIPDSVRDGLAYRGRVFLELITQI 473
              T     GF+P FGP +L L+G  +      +    +     +G+AYRGR+ +EL T +
Sbjct: 475  --TGETEVGFVPTFGPCYLNLYGSPREYTGFPDPYDELNTGKGEGVAYRGRILVELATFL 532

Query: 474  -KSYQDSTIKDLSHE-VTRIEKHQNRQKYGLCVIFLSCTMMPNFKELIHFEVSIGHYGNK 531
             K+  D  ++ +S++ +  +EK+Q R+KY L  +F S TM+ +  E I FEVSIG+YGNK
Sbjct: 533  EKTPPDKKLEPISNDDLLVVEKYQRRRKYSLSAVFHSATMLQDVGEAIQFEVSIGNYGNK 592

Query: 532  MDLNYKPLVSSTPYSPVIYDGNIYHYVPWYNTKPVVAVTSNWEDVSFRMNCLNLLHFTRD 591
             D   KPL S+T YS  ++DGN Y+Y+PW +TKPVV +TS WED+S R++ +N L    +
Sbjct: 593  FDTTCKPLASTTQYSRAVFDGNYYYYLPWAHTKPVVTLTSYWEDISHRLDAVNTLLAMAE 652

Query: 592  RLKANLDTLKSTRNPKDPA--LLYQWEKLLRELAEDCKRPLPCMTYQPKATSLDRKRWQL 649
            RL+ N++ LKS    K PA  L   W KL+ E+ ED +  LP    +   T LD +  +L
Sbjct: 653  RLQTNIEALKSGIQGKIPANQLAELWLKLIDEVIEDTRYTLPLTEGKANVTVLDTQIRKL 712

Query: 650  RSLLLQELAQKAKQAKP-----KDMVATAEDWLYRLNTVLPEPQMGLPDVMIWLVAKEQR 704
            RS  L ++ + A + +      K  +A  EDWL +L  +  EPQ  +PD++IW++  E+R
Sbjct: 713  RSRSLSQIHEAAVRMRSEATDVKSTLAEIEDWLDKLMQLTEEPQNSMPDIIIWMIRGEKR 772

Query: 705  VAYAQVPAHSVLFSPAGALHSGRLCGKIQTLFLQYPEGEGQKDVLPAHLRVCMWLGNVTD 764
            +AYA++PAH VL+S +G   SG+ CGK QT+FL+YP+ +     +P  LRV +WLG    
Sbjct: 773  LAYARIPAHQVLYSTSGENASGKYCGKTQTIFLKYPQEKNNGPKVPVELRVNIWLGLSAV 832

Query: 765  SKDLQLLRQGDTAVYAEMYENQAKYKDQWGQQGLYHCPNFSDVMGNKTLPMTDFQPPLGW 824
             K      +G   V+AEMYENQA    +WG  GL     FSDV G   L    F PP GW
Sbjct: 833  EKKFNSFAEGTFTVFAEMYENQALMFGKWGTSGLVGRHKFSDVTGKIKLKREFFLPPKGW 892

Query: 825  HWQDSWTVEPQRRLLLDIDINKSQVLEEVYENQGRDTRGAWGPAAIPNTDVNGQPMEARE 884
             W+  W V+P+R LL + D   ++  +EVY+N+ R   G W PA    TD NG    +  
Sbjct: 893  EWEGEWIVDPERSLLTEADAGHTEFTDEVYQNESRYPGGDWKPAEDTYTDANGDKAASPS 952

Query: 885  NVKCPQGWHFKKD-WVVELNHAVDS--WEYGVGIPPSGLPQVWSPVEKTYHSCRRRRWAR 941
             + CP GW ++ D W  ++N AVD   WEYG+ IPP   P+ W   EK YH+ RRRR  R
Sbjct: 953  ELTCPPGWEWEDDAWSYDINRAVDEKGWEYGITIPPDHKPKSWVAAEKMYHTHRRRRLVR 1012

Query: 942  VRFRNHGEL-SHEQETLSFLQLGLAKGEEEGWEYDTF-GSKFHLNPQPQSRFRRRCWRRR 999
             R ++  +  S     +  LQ      ++EGWEY +  G KFH   +    FRRR WRR+
Sbjct: 1013 KRKKDLTQTASSTARAMEELQ------DQEGWEYASLIGWKFHWKQRSSDTFRRRRWRRK 1066

Query: 1000 LAPNKDKGIAPIFLLEGSLACEGGSVREEGDWAWARGNRSSTQEPQGRLSWVQAMDLKYH 1059
            +AP++  G A IF LEG+L   G    E+GD                          +  
Sbjct: 1067 MAPSETHGAAAIFKLEGAL---GADTTEDGD--------------------------EKS 1097

Query: 1060 AGKEEDSKTWPWGLDRQFRDPQRQDTRPPNLPFIYCTFNKPHYYQLFCYIYQARNLVSNQ 1119
              K++ S T  +G                N P + C F++ + Y L CY+YQARNL++  
Sbjct: 1098 LEKQKHSATTVFGA---------------NTPIVSCNFDRVYIYHLRCYVYQARNLLALD 1142

Query: 1120 ILTFQGPFIRVVFLNHSQCTQTLRSSAGPTWAQTLIFQHLLLYENPQDTKESPPLVVLEL 1179
              +F  P+  + FL+ S+ T+ + S+  PTW QT+IF  + +Y  PQ   ++PP V++EL
Sbjct: 1143 KDSFSDPYAHICFLHRSKTTEIIHSTLNPTWDQTIIFDEVEIYGEPQTVLQNPPKVIMEL 1202

Query: 1180 WQRDFWGKESLWGRSVWPPMVWLDLQDRILPPMRWHPLVKELGKEEGEILASCELILQTE 1239
            +  D  GK+   GRS++ P+V L+ +  I P + WHP++    K  G++L + ELIL+ +
Sbjct: 1203 FDNDQVGKDEFLGRSIFSPVVKLNSEMDITPKLLWHPVMNG-DKACGDVLVTAELILRGK 1261

Query: 1240 KLGEKQLPILSVPWKNGAYTLPKSIQPTIKRMAIEILAWGLRNMKK-----ASSPQLLVE 1294
                  LPIL        Y +P+ I+P ++  AIEILAWGLRNMK       +SP L+VE
Sbjct: 1262 D--GSNLPILPPQRAPNLYMVPQGIRPVVQLTAIEILAWGLRNMKNFQMASITSPSLVVE 1319

Query: 1295 FGEESLRTEPIRDFQTNPNFPESESVLVLTVLMPTEEAYALPLVVKVVDNWAFGQQTVTG 1354
             G E + +  I++ +  PNFP S  VL + V +P EE Y  PLV+KV+D+  FG++ V G
Sbjct: 1320 CGGERVESVVIKNLKKTPNFPSS--VLFMKVFLPKEELYMPPLVIKVIDHRQFGRKPVVG 1377

Query: 1355 QANIDFLQPYFCDPWA-QDYMHPKLPT--LSEKKHQDFLGYLYRKFWFKSSKAEDEYEHE 1411
            Q  I+ L  + CDP+A ++ + P+L    LS    +D +  +       +SK  ++ E  
Sbjct: 1378 QCTIERLDRFRCDPYAGKEDIVPQLKASLLSAPPCRDIVIEMEDTKPLLASKLTEKEEEI 1437

Query: 1412 VDWWSKLFWATDEHKSL-KYKYKDYHTLKVYECELEAVPAFQGLQDFCQTFKLYQ--EQP 1468
            VDWWSK + ++ EH+   +Y  K Y  LK+Y CELE V  F+GL DF  TFKLY+     
Sbjct: 1438 VDWWSKFYASSGEHEKCGQYIQKGYSKLKIYNCELENVAEFEGLTDFSDTFKLYRGKSDE 1497

Query: 1469 KLDSPVVGEFKGLFRIYPFPENPEAPKPPLQFLVWPEREDFPQPCLVRVYMVRAINLQPQ 1528
              D  VVGEFKG FRIYP P++P  P PP QF   P+    PQ C VR+Y+VR + LQPQ
Sbjct: 1498 NEDPSVVGEFKGSFRIYPLPDDPSVPAPPRQFRELPD--SVPQECTVRIYIVRGLELQPQ 1555

Query: 1529 DYNGLCDPYVILKLGKTELGNRDMYQPNTLDPIFGMMFELTCNIPLEKDLEIQLYDFDLF 1588
            D NGLCDPY+ + LGK  + +RD Y PNTL+P+FG M+EL+C +P EKDL+I +YD+D F
Sbjct: 1556 DNNGLCDPYIKITLGKKVIEDRDHYIPNTLNPVFGRMYELSCYLPQEKDLKISVYDYDTF 1615

Query: 1589 SPDDKIGTTVIDLENRLLSGFGAHCGLSKSYCQSGPFRWRDQMPPSYLLERYAKRKGLPP 1648
            + D+K+G T+IDLENR LS FG+HCG+ + YC SG   WRDQ+ P+ LL+  A+ KG P 
Sbjct: 1616 TRDEKVGETIIDLENRFLSRFGSHCGIPEEYCVSGVNTWRDQLRPTQLLQNVARFKGFPQ 1675

Query: 1649 PLFSPEEDAVFYNGKKFKLQSFEPKTPTVHGLGPKKERLALYLLHTQGLVPEHVETRTLY 1708
            P+ S +   + Y G+ + L  FE        LG  +ERLAL++L TQGLVPEHVETRTL+
Sbjct: 1676 PILSEDGSRIRYGGRDYSLDEFEANKILHQHLGAPEERLALHILRTQGLVPEHVETRTLH 1735

Query: 1709 SHSQPGIDQGKVQMWVDIFPKKLGPPGPQVNINPRKPKRKASEHSGHRYELRCIIWKTAN 1768
            S  QP I QGK+QMWVD+FPK LGPPGP  NI PRK K         +Y LR IIW T +
Sbjct: 1736 STFQPNISQGKLQMWVDVFPKSLGPPGPPFNITPRKAK---------KYYLRVIIWNTKD 1786

Query: 1769 VDLVDDNLSREKTSDIYIKGWLYGLEKDMQKTDIHYHSLTGEADFNWRFIFTMDYLAAER 1828
            V L + +++ E+ SDIY+KGW+ G E++ QKTD+HY SL GE +FNWRF+F  DYL AE+
Sbjct: 1787 VILDEKSITGEEMSDIYVKGWIPGNEENKQKTDVHYRSLDGEGNFNWRFVFPFDYLPAEQ 1846

Query: 1829 TCVQSQKDYIWSLDATSMKFPARLIIQVWDNDIFSPDDFLGVLELDLSDMPLPARHAKQC 1888
             C+ ++K++ WS+D T  + P RLIIQ+WDND FS DD+LG LELDL    +PA+  ++C
Sbjct: 1847 LCIVAKKEHFWSIDQTEFRIPPRLIIQIWDNDKFSLDDYLGFLELDLRHTIIPAKSPEKC 1906

Query: 1889 SIRMMDADPKWPYFIQYKHFSLFKKKTVTGWWPCQVLDGGKWRLSGKVKMSLEILSEKEA 1948
             + M+  D K    ++ K  SLF++K++ GWWPC     G   ++GKV+M+LEIL+EKEA
Sbjct: 1907 RLDMI-PDLKAMNPLKAKTASLFEQKSMKGWWPCYAEKDGARVMAGKVEMTLEILNEKEA 1965

Query: 1949 LIKPAGRGQSEPNQYPTLHPPLRTNTSFTWLRSPVQNFCYIFWKRYRFKLIAFMVISIIA 2008
              +PAG+G+ EPN  P L  P R  TSF W  +P +   +I W+R+++ +I  + + I+ 
Sbjct: 1966 DERPAGKGRDEPNMNPKLDLPNRPETSFLWFTNPCKTMKFIVWRRFKWVIIGLLFLLILL 2025

Query: 2009 LMLFNFIYSAPHYLAMSWIKPQL 2031
            L +   +YS P+YL+M  +KP +
Sbjct: 2026 LFVAVLLYSLPNYLSMKIVKPNV 2048


>gi|195976821 dysferlin isoform 2 [Homo sapiens]
          Length = 2081

 Score = 1441 bits (3729), Expect = 0.0
 Identities = 855/2160 (39%), Positives = 1212/2160 (56%), Gaps = 254/2160 (11%)

Query: 21   PCMSIDFRDIKKRTRVVEGN-DPVWNETLIWHLWNRPLENDSFLQVTLQDMGSQKKERFI 79
            P  S+ FR +KKRT+V++ + +PVWNE   W L   PL+  S L V ++D  +  + RF+
Sbjct: 23   PVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLDQGSELHVVVKDHETMGRNRFL 82

Query: 80   GLATVLLKPLLKQPSEVLFVKDLTLLNHSMKPTDCTVTLQVAH----------------- 122
            G A V L+ +L  PS +    +  LL+   +PT  ++ LQV++                 
Sbjct: 83   GEAKVPLREVLATPS-LSASFNAPLLDTKKQPTGASLVLQVSYTPLPGAVPLFPPPTPLE 141

Query: 123  ----MSNQDI-EKTGAEDHL---GITAREA--------------ASQKLM------VPG- 153
                + + D+   TG E+     G+T  EA                +KL        PG 
Sbjct: 142  PSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGI 201

Query: 154  ------STAHRALSSKPQHFQVRVKVFEARQLMGNNIKPVVKVSIAGQQHQTRIKMGNNP 207
                   T+ + LS KPQ FQ+RV+V E RQL G NIKPVVKV+ AGQ  +TRI  GN+P
Sbjct: 202  KRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSP 261

Query: 208  FFNEIFFQNFHEVPAKFFDETILI-----------------QTDIGFIYHSPGHTLLRKW 250
             FNE  F N  + P + FDE I I                 + D+G IY  P H  LRKW
Sbjct: 262  LFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKW 321

Query: 251  LGLCQPNNPGSGVTGYLKVTIYALGVGDQALIDQK-LLYGTDDTDIQIFKSAVVPINMAY 309
            L L  P++  +G  GYLK ++  LG GD+A +++K      +D +  + +   V +  A+
Sbjct: 322  LLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAH 381

Query: 310  LQLFIYCAEDL-----------------HLKKHQSVNPQLEVELIGEKLRTHMQTQTDNP 352
              L ++ AEDL                    K   V+P +EV   G+ L + +  +T NP
Sbjct: 382  FCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANP 441

Query: 353  IWNQILTFRIQLPCLSSYIKFRVLDCRKKDCPDEIGTASLSLNQISSTGEEIEGKQS--L 410
             WNQ +T     P +   ++ R++D  +    D + T  LS+++IS+ G EIE + +  +
Sbjct: 442  QWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEEEPAGAV 501

Query: 411  EPTSYTPRV-YSGFLPCFGPSFLTLHGGKKAPFRIQEEGACIPDSVRDGLAYRGRVFLEL 469
            +P+  +    Y GFLP FGP ++ L+G  +      +    +     +G+AYRGR+ L L
Sbjct: 502  KPSKASDLDDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSL 561

Query: 470  ITQIKSYQDSTIKDL-SHEVTRIEKHQNRQKYGLCVIFLSCTMMPNFKELIHFEVSIGHY 528
             T++  + +  ++DL + ++ R+EK+  R+KY L   F S TM+ +  + I FEVSIG+Y
Sbjct: 562  ETKLVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNY 621

Query: 529  GNKMDLNYKPLVSSTPYSPVIYDGNIYHYVPWYNTKPVVAVTSNWEDVSFRMNCLNLLHF 588
            GNK D+   PL S+T YS  ++DG  Y+Y+PW N KPVV ++S WED+S R+   N L  
Sbjct: 622  GNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLG 681

Query: 589  TRDRLKANLD----TLKSTRNPKDPALLYQWEKLLRELAEDCKRPLPCMTYQPKATSLDR 644
              DRL+A L+     LK+  + +D   L    +L  EL   C +PL  +   P AT LD+
Sbjct: 682  IADRLEAGLEQVHLALKAQCSTEDVDSLVA--QLTDELIAGCSQPLGDIHETPSATHLDQ 739

Query: 645  KRWQLRSLLLQE-----LAQKAKQAKPKDMVATAEDWLYRLNTVLPEPQMGLPDVMIWLV 699
              +QLR+  L +     LA K   ++    +  AEDWL RL  +  EPQ  LPD++IW++
Sbjct: 740  YLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWML 799

Query: 700  AKEQRVAYAQVPAHSVLFSPAGALHSGRLCGKIQTLFLQYPEGEGQKDVLPAHLRVCMWL 759
              ++RVAY +VPAH VLFS  GA + G+ CGK+QT+FL+YP  +     +P  +RV +W 
Sbjct: 800  QGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWF 859

Query: 760  GNVTDSKDLQLLRQGDTAVYAEMYENQAKYK--DQWGQQGLYHCPNFSDVMGNKTLPMTD 817
            G   D K+     +G  +V+AE YEN+ K      WG  GL + P FSDV G   LP   
Sbjct: 860  GLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTTGLTY-PKFSDVTGKIKLPKDS 918

Query: 818  FQPPLGWHWQDSWTVEPQRRLLLDIDINKSQVLEEVYENQGRDTRGAWGPAAIPNTDVNG 877
            F+P  GW W   W V P++ LL D+D      +EEV+ENQ R   G W   +   TDVNG
Sbjct: 919  FRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNG 978

Query: 878  QPMEARENVKCPQGWHFK-KDWVVELNHAVDS--WEYGVGIPPSGLPQVWSPVEKTYHSC 934
            + +  +++++CP GW ++ ++W  +LN AVD   WEY + IPP   P+ W P EK Y++ 
Sbjct: 979  EKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTH 1038

Query: 935  RRRRWARVRFRNHGELS----HEQETLSFLQLGLAKGEEEGWEYDT-FGSKFHLNPQPQS 989
            RRRRW R+R R+  ++     H Q          A+ E EGWEY + FG KFHL  +   
Sbjct: 1039 RRRRWVRLRRRDLSQMEALKRHRQ----------AEAEGEGWEYASLFGWKFHLEYRKTD 1088

Query: 990  RFRRRCWRRRLAPNKDKGIAPIFLLEGSLACEGGSVREEGDWAWARGNRSSTQEPQGRLS 1049
             FRRR WRRR+ P +  G A +F LEG+L    G V ++                     
Sbjct: 1089 AFRRRRWRRRMEPLEKTGPAAVFALEGAL----GGVMDD--------------------- 1123

Query: 1050 WVQAMDLKYHAGKEEDS---KTWPWGLDRQFRDPQRQDTRPPNLPFIYCTFNKPHYYQLF 1106
                        K EDS    T  +G++R               P I C F+  + Y L 
Sbjct: 1124 ------------KSEDSMSVSTLSFGVNR---------------PTISCIFDYGNRYHLR 1156

Query: 1107 CYIYQARNLVSNQILTFQGPFIRVVFLNHSQCTQTLRSSAGPTWAQTLIFQHLLLYENPQ 1166
            CY+YQAR+L +    +F  P+  V FL+ SQ T  ++++  PTW QTLIF  + ++  P 
Sbjct: 1157 CYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPA 1216

Query: 1167 DTKESPPLVVLELWQRDFWGKESLWGRSVWPPMVWLDLQDRILPPMRWHPLVKELGKEEG 1226
               E PP +V+EL+  D +G +   GR +  P +        +P + W PL +   +  G
Sbjct: 1217 TVAEQPPSIVVELYDHDTYGADEFMGRCICQPSL------ERMPRLAWFPLTRG-SQPSG 1269

Query: 1227 EILASCELILQTEKLGEKQLPILSV---------------PW-----KNGAYTLPKSIQP 1266
            E+LAS ELI Q EK     +P   V               P+     +   Y +P++I+P
Sbjct: 1270 ELLASFELI-QREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKP 1328

Query: 1267 TIKRMAIEILAWGLRNMKK-----ASSPQLLVEFGEESLRTEPIRDFQTNPNFPESESVL 1321
             ++R AIEILAWGLRNMK       SSP L+VE G +++++  IR+ + NPNF      L
Sbjct: 1329 ALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPNF--DICTL 1386

Query: 1322 VLTVLMPTEEAYALPLVVKVVDNWAFGQQTVTGQANIDFLQPYFCDPWAQDYMHPK---- 1377
             + V++P EE Y  P+ VKV+DN  FG++ V GQ  I  L+ + CDP++ +   P+    
Sbjct: 1387 FMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPD 1446

Query: 1378 -LPTLSEKKHQDFLGYLYRKFWFKSSKAEDEYEHEVDWWSKLFWATDEHKSL-KYKYKDY 1435
             +  LS    +D L  +  K          + E  +DWWSK F +  E +    Y  KD+
Sbjct: 1447 DVSLLSPG--EDVLIDIDDK----EPLIPIQEEEFIDWWSKFFASIGEREKCGSYLEKDF 1500

Query: 1436 HTLKVYECELEAVPAFQGLQDFCQTFKLYQ---EQPKLDSPVVGEFKGLFRIYPFPENPE 1492
             TLKVY+ +LE V AF+GL DFC TFKLY+   ++   D  V+GEFKGLF+IYP PE+P 
Sbjct: 1501 DTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPA 1560

Query: 1493 APKPPLQFLVWPEREDFPQPCLVRVYMVRAINLQPQDYNGLCDPYVILKLGKTELGNRDM 1552
             P PP QF     +   PQ CLVR+Y+VRA  LQP+D NG CDPY+ + +GK  + ++D 
Sbjct: 1561 IPMPPRQFHQLAAQG--PQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDN 1618

Query: 1553 YQPNTLDPIFGMMFELTCNIPLEKDLEIQLYDFDLFSPDDKIGTTVIDLENRLLSGFGAH 1612
            Y P TL+P+FG MFELTC +PLEKDL+I LYD+DL S D+KIG TV+DLENRLLS FGA 
Sbjct: 1619 YIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGAR 1678

Query: 1613 CGLSKSYCQSGPFRWRDQMPPSYLLERYAKRKGLPPPLFSPEEDAVFYNGKKFKLQSFEP 1672
            CGL ++YC SGP +WRDQ+ PS LL  + ++  +  P++    D V +  K++ ++  E 
Sbjct: 1679 CGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVY--RTDRVMFQDKEYSIEEIEA 1736

Query: 1673 -KTPTVHGLGPKKERLALYLLHTQGLVPEHVETRTLYSHSQPGIDQGKVQMWVDIFPKKL 1731
             + P  H LGP +ERLAL++L  QGLVPEHVE+R LYS  QP I+QGK+QMWVD+FPK L
Sbjct: 1737 GRIPNPH-LGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKAL 1795

Query: 1732 GPPGPQVNINPRKPKRKASEHSGHRYELRCIIWKTANVDLVDDNLSREKTSDIYIKGWLY 1791
            G PGP  NI PR+ +         R+ LRCIIW T +V L D +L+ EK SDIY+KGW+ 
Sbjct: 1796 GRPGPPFNITPRRAR---------RFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMI 1846

Query: 1792 GLEKDMQKTDIHYHSLTGEADFNWRFIFTMDYLAAERTCVQSQKDYIWSLDATSMKFPAR 1851
            G E+  QKTD+HY SL GE +FNWRFIF  DYL AE+ C  ++KD  W LD T  K PAR
Sbjct: 1847 GFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPAR 1906

Query: 1852 LIIQVWDNDIFSPDDFLGVLELDLSDMPLPARHAKQCSIRMMD--ADPKWPYFIQYKHFS 1909
            ++ Q+WDND FS DDFLG L+LDL+ MP PA+ AK+CS+  +D    P+W         S
Sbjct: 1907 VVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEW-------FVS 1959

Query: 1910 LFKKKTVTGWWPCQVLDGGKWRLSGKVKMSLEILSEKEALIKPAGRGQSEPNQYPTLHPP 1969
            LF++KTV GWWPC   +G K  L+GK++M+LEI++E E   +PAG+G+ EPN  P L  P
Sbjct: 1960 LFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDP 2019

Query: 1970 LRTNTSFTWLRSPVQNFCYIFWKRYRFKLIAFMVISIIALMLFNFIYSAPHYLAMSWIKP 2029
             R +TSF W  SP +   +I W+R+R+ +I F+++ I+ L L  FIY+ P+Y AM  +KP
Sbjct: 2020 RRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKP 2079



 Score = 40.0 bits (92), Expect = 0.024
 Identities = 24/86 (27%), Positives = 46/86 (53%), Gaps = 1/86 (1%)

Query: 20  RPCMSIDFRDIKKRTRVVEGNDPVWNETLIWHLWNRPLE-NDSFLQVTLQDMGSQKKERF 78
           +P + +      KRTR+ +GN P++NETL ++L++ P E  D  + +T+ D  S + +  
Sbjct: 239 KPVVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDAL 298

Query: 79  IGLATVLLKPLLKQPSEVLFVKDLTL 104
           +G   + +  + ++P      K L L
Sbjct: 299 LGEFRMDVGTIYREPRHAYLRKWLLL 324


>gi|195976777 dysferlin isoform 3 [Homo sapiens]
          Length = 2067

 Score = 1439 bits (3726), Expect = 0.0
 Identities = 854/2157 (39%), Positives = 1205/2157 (55%), Gaps = 262/2157 (12%)

Query: 21   PCMSIDFRDIKKRTRVVEGN-DPVWNETLIWHLWNRPLENDSFLQVTLQDMGSQKKERFI 79
            P  S+ FR +KKRT+V++ + +PVWNE   W L   PL+  S L V ++D  +  + RF+
Sbjct: 23   PVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLDQGSELHVVVKDHETMGRNRFL 82

Query: 80   GLATVLLKPLLKQPSEVLFVKDLTLLNHSMKPTDCTVTLQVAH----------------- 122
            G A V L+ +L  PS +    +  LL+   +PT  ++ LQV++                 
Sbjct: 83   GEAKVPLREVLATPS-LSASFNAPLLDTKKQPTGASLVLQVSYTPLPGAVPLFPPPTPLE 141

Query: 123  ----MSNQDI-EKTGAEDHL---GITAREA--------------ASQKLM------VPG- 153
                + + D+   TG E+     G+T  EA                +KL        PG 
Sbjct: 142  PSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGI 201

Query: 154  ------STAHRALSSKPQHFQVRVKVFEARQLMGNNIKPVVKVSIAGQQHQTRIKMGNNP 207
                   T+ + LS KPQ FQ+RV+V E RQL G NIKPVVKV+ AGQ  +TRI  GN+P
Sbjct: 202  KRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSP 261

Query: 208  FFNEIFFQNFHEVPAKFFDETILI-----------------QTDIGFIYHSPGHTLLRKW 250
             FNE  F N  + P + FDE I I                 + D+G IY  P H  LRKW
Sbjct: 262  LFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKW 321

Query: 251  LGLCQPNNPGSGVTGYLKVTIYALGVGDQALIDQK-LLYGTDDTDIQIFKSAVVPINMAY 309
            L L  P++  +G  GYLK ++  LG GD+A +++K      +D +  + +   V +  A+
Sbjct: 322  LLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAH 381

Query: 310  LQLFIYCAEDL-----------------HLKKHQSVNPQLEVELIGEKLRTHMQTQTDNP 352
              L ++ AEDL                    K   V+P +EV   G+ L + +  +T NP
Sbjct: 382  FCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANP 441

Query: 353  IWNQILTFRIQLPCLSSYIKFRVLDCRKKDCPDEIGTASLSLNQISSTGEEIEGKQSLEP 412
             WNQ +T     P +   ++ R++D  +    D + T  LS+++IS+ G EIE       
Sbjct: 442  QWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEVDD---- 497

Query: 413  TSYTPRVYSGFLPCFGPSFLTLHGGKKAPFRIQEEGACIPDSVRDGLAYRGRVFLELITQ 472
                   Y GFLP FGP ++ L+G  +      +    +     +G+AYRGR+ L L T+
Sbjct: 498  -------YLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETK 550

Query: 473  IKSYQDSTIKDL-SHEVTRIEKHQNRQKYGLCVIFLSCTMMPNFKELIHFEVSIGHYGNK 531
            +  + +  ++DL + ++ R+EK+  R+KY L   F S TM+ +  + I FEVSIG+YGNK
Sbjct: 551  LVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNK 610

Query: 532  MDLNYKPLVSSTPYSPVIYDGNIYHYVPWYNTKPVVAVTSNWEDVSFRMNCLNLLHFTRD 591
             D+   PL S+T YS  ++DG  Y+Y+PW N KPVV ++S WED+S R+   N L    D
Sbjct: 611  FDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIAD 670

Query: 592  RLKANLD----TLKSTRNPKDPALLYQWEKLLRELAEDCKRPLPCMTYQPKATSLDRKRW 647
            RL+A L+     LK+  + +D   L    +L  EL   C +PL  +   P AT LD+  +
Sbjct: 671  RLEAGLEQVHLALKAQCSTEDVDSLVA--QLTDELIAGCSQPLGDIHETPSATHLDQYLY 728

Query: 648  QLRSLLLQE-----LAQKAKQAKPKDMVATAEDWLYRLNTVLPEPQMGLPDVMIWLVAKE 702
            QLR+  L +     LA K   ++    +  AEDWL RL  +  EPQ  LPD++IW++  +
Sbjct: 729  QLRTHHLSQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGD 788

Query: 703  QRVAYAQVPAHSVLFSPAGALHSGRLCGKIQTLFLQYPEGEGQKDVLPAHLRVCMWLGNV 762
            +RVAY +VPAH VLFS  GA + G+ CGK+QT+FL+YP  +     +P  +RV +W G  
Sbjct: 789  KRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLS 848

Query: 763  TDSKDLQLLRQGDTAVYAEMYENQAKYK--DQWGQQGLYHCPNFSDVMGNKTLPMTDFQP 820
             D K+     +G  +V+AE YEN+ K      WG  GL + P FSDV G   LP   F+P
Sbjct: 849  VDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTTGLTY-PKFSDVTGKIKLPKDSFRP 907

Query: 821  PLGWHWQDSWTVEPQRRLLLDIDINKSQVLEEVYENQGRDTRGAWGPAAIPNTDVNGQPM 880
              GW W   W V P++ LL D+D      +EEV+ENQ R   G W   +   TDVNG+ +
Sbjct: 908  SAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKV 967

Query: 881  EARENVKCPQGWHFK-KDWVVELNHAVDS--WEYGVGIPPSGLPQVWSPVEKTYHSCRRR 937
              +++++CP GW ++ ++W  +LN AVD   WEY + IPP   P+ W P EK Y++ RRR
Sbjct: 968  LPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRR 1027

Query: 938  RWARVRFRNHGELS----HEQETLSFLQLGLAKGEEEGWEYDT-FGSKFHLNPQPQSRFR 992
            RW R+R R+  ++     H Q          A+ E EGWEY + FG KFHL  +    FR
Sbjct: 1028 RWVRLRRRDLSQMEALKRHRQ----------AEAEGEGWEYASLFGWKFHLEYRKTDAFR 1077

Query: 993  RRCWRRRLAPNKDKGIAPIFLLEGSLACEGGSVREEGDWAWARGNRSSTQEPQGRLSWVQ 1052
            RR WRRR+ P +  G A +F LEG+L    G V ++                        
Sbjct: 1078 RRRWRRRMEPLEKTGPAAVFALEGAL----GGVMDD------------------------ 1109

Query: 1053 AMDLKYHAGKEEDS---KTWPWGLDRQFRDPQRQDTRPPNLPFIYCTFNKPHYYQLFCYI 1109
                     K EDS    T  +G++R               P I C F+  + Y L CY+
Sbjct: 1110 ---------KSEDSMSVSTLSFGVNR---------------PTISCIFDYGNRYHLRCYM 1145

Query: 1110 YQARNLVSNQILTFQGPFIRVVFLNHSQCTQTLRSSAGPTWAQTLIFQHLLLYENPQDTK 1169
            YQAR+L +    +F  P+  V FL+ SQ T  ++++  PTW QTLIF  + ++  P    
Sbjct: 1146 YQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVA 1205

Query: 1170 ESPPLVVLELWQRDFWGKESLWGRSVWPPMVWLDLQDRILPPMRWHPLVKELGKEEGEIL 1229
            E PP +V+EL+  D +G +   GR +  P +        +P + W PL +   +  GE+L
Sbjct: 1206 EQPPSIVVELYDHDTYGADEFMGRCICQPSL------ERMPRLAWFPLTRG-SQPSGELL 1258

Query: 1230 ASCELILQTEKLGEKQLPILSV---------------PW-----KNGAYTLPKSIQPTIK 1269
            AS ELI Q EK     +P   V               P+     +   Y +P++I+P ++
Sbjct: 1259 ASFELI-QREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQ 1317

Query: 1270 RMAIEILAWGLRNMKK-----ASSPQLLVEFGEESLRTEPIRDFQTNPNFPESESVLVLT 1324
            R AIEILAWGLRNMK       SSP L+VE G +++++  IR+ + NPNF      L + 
Sbjct: 1318 RTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPNF--DICTLFME 1375

Query: 1325 VLMPTEEAYALPLVVKVVDNWAFGQQTVTGQANIDFLQPYFCDPWAQDYMHPK-----LP 1379
            V++P EE Y  P+ VKV+DN  FG++ V GQ  I  L+ + CDP++ +   P+     + 
Sbjct: 1376 VMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVS 1435

Query: 1380 TLSEKKHQDFLGYLYRKFWFKSSKAEDEYEHEVDWWSKLFWATDEHKSL-KYKYKDYHTL 1438
             LS    +D L  +  K          + E  +DWWSK F +  E +    Y  KD+ TL
Sbjct: 1436 LLSPG--EDVLIDIDDK----EPLIPIQEEEFIDWWSKFFASIGEREKCGSYLEKDFDTL 1489

Query: 1439 KVYECELEAVPAFQGLQDFCQTFKLYQ---EQPKLDSPVVGEFKGLFRIYPFPENPEAPK 1495
            KVY+ +LE V AF+GL DFC TFKLY+   ++   D  V+GEFKGLF+IYP PE+P  P 
Sbjct: 1490 KVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPM 1549

Query: 1496 PPLQFLVWPEREDFPQPCLVRVYMVRAINLQPQDYNGLCDPYVILKLGKTELGNRDMYQP 1555
            PP QF     +   PQ CLVR+Y+VRA  LQP+D NG CDPY+ + +GK  + ++D Y P
Sbjct: 1550 PPRQFHQLAAQG--PQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIP 1607

Query: 1556 NTLDPIFGMMFELTCNIPLEKDLEIQLYDFDLFSPDDKIGTTVIDLENRLLSGFGAHCGL 1615
             TL+P+FG MFELTC +PLEKDL+I LYD+DL S D+KIG TV+DLENRLLS FGA CGL
Sbjct: 1608 CTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGL 1667

Query: 1616 SKSYCQSGPFRWRDQMPPSYLLERYAKRKGLPPPLFSPEEDAVFYNGKKFKLQSFEP-KT 1674
             ++YC SGP +WRDQ+ PS LL  + ++  +  P++    D V +  K++ ++  E  + 
Sbjct: 1668 PQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVY--RTDRVMFQDKEYSIEEIEAGRI 1725

Query: 1675 PTVHGLGPKKERLALYLLHTQGLVPEHVETRTLYSHSQPGIDQGKVQMWVDIFPKKLGPP 1734
            P  H LGP +ERLAL++L  QGLVPEHVE+R LYS  QP I+QGK+QMWVD+FPK LG P
Sbjct: 1726 PNPH-LGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRP 1784

Query: 1735 GPQVNINPRKPKRKASEHSGHRYELRCIIWKTANVDLVDDNLSREKTSDIYIKGWLYGLE 1794
            GP  NI PR+ +         R+ LRCIIW T +V L D +L+ EK SDIY+KGW+ G E
Sbjct: 1785 GPPFNITPRRAR---------RFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFE 1835

Query: 1795 KDMQKTDIHYHSLTGEADFNWRFIFTMDYLAAERTCVQSQKDYIWSLDATSMKFPARLII 1854
            +  QKTD+HY SL GE +FNWRFIF  DYL AE+ C  ++KD  W LD T  K PAR++ 
Sbjct: 1836 EHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVF 1895

Query: 1855 QVWDNDIFSPDDFLGVLELDLSDMPLPARHAKQCSIRMMD--ADPKWPYFIQYKHFSLFK 1912
            Q+WDND FS DDFLG L+LDL+ MP PA+ AK+CS+  +D    P+W         SLF+
Sbjct: 1896 QIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEW-------FVSLFE 1948

Query: 1913 KKTVTGWWPCQVLDGGKWRLSGKVKMSLEILSEKEALIKPAGRGQSEPNQYPTLHPPLRT 1972
            +KTV GWWPC   +G K  L+GK++M+LEI++E E   +PAG+G+ EPN  P L  P R 
Sbjct: 1949 QKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRP 2008

Query: 1973 NTSFTWLRSPVQNFCYIFWKRYRFKLIAFMVISIIALMLFNFIYSAPHYLAMSWIKP 2029
            +TSF W  SP +   +I W+R+R+ +I F+++ I+ L L  FIY+ P+Y AM  +KP
Sbjct: 2009 DTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKP 2065



 Score = 40.0 bits (92), Expect = 0.024
 Identities = 24/86 (27%), Positives = 46/86 (53%), Gaps = 1/86 (1%)

Query: 20  RPCMSIDFRDIKKRTRVVEGNDPVWNETLIWHLWNRPLE-NDSFLQVTLQDMGSQKKERF 78
           +P + +      KRTR+ +GN P++NETL ++L++ P E  D  + +T+ D  S + +  
Sbjct: 239 KPVVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDAL 298

Query: 79  IGLATVLLKPLLKQPSEVLFVKDLTL 104
           +G   + +  + ++P      K L L
Sbjct: 299 LGEFRMDVGTIYREPRHAYLRKWLLL 324


>gi|195976769 dysferlin isoform 6 [Homo sapiens]
          Length = 2102

 Score = 1438 bits (3723), Expect = 0.0
 Identities = 858/2178 (39%), Positives = 1216/2178 (55%), Gaps = 269/2178 (12%)

Query: 21   PCMSIDFRDIKKRTRVVEGN-DPVWNETLIWHLWNRPLENDSFLQVTLQDMGSQKKERFI 79
            P  S+ FR +KKRT+V++ + +PVWNE   W L   PL+  S L V ++D  +  + RF+
Sbjct: 23   PVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLDQGSELHVVVKDHETMGRNRFL 82

Query: 80   GLATVLLKPLLKQPSEVLFVKDLTLLNHSMKPTDCTVTLQVAH----------------- 122
            G A V L+ +L  PS +    +  LL+   +PT  ++ LQV++                 
Sbjct: 83   GEAKVPLREVLATPS-LSASFNAPLLDTKKQPTGASLVLQVSYTPLPGAVPLFPPPTPLE 141

Query: 123  ----MSNQDI-EKTGAEDHL---GITAREA--------------ASQKLM------VPG- 153
                + + D+   TG E+     G+T  EA                +KL        PG 
Sbjct: 142  PSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGI 201

Query: 154  ------STAHRALSSKPQHFQVRVKVFEARQLMGNNIKPVVKVSIAGQQHQTRIKMGNNP 207
                   T+ + LS KPQ FQ+RV+V E RQL G NIKPVVKV+ AGQ  +TRI  GN+P
Sbjct: 202  KRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSP 261

Query: 208  FFNEIFFQNFHEVPAKFFDETILI-----------------QTDIGFIYHSPGHTLLRKW 250
             FNE  F N  + P + FDE I I                 + D+G IY  P H  LRKW
Sbjct: 262  LFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKW 321

Query: 251  LGLCQPNNPGSGVTGYLKVTIYALGVGDQALIDQK-LLYGTDDTDIQIFKSAVVPINMAY 309
            L L  P++  +G  GYLK ++  LG GD+A +++K      +D +  + +   V +  A+
Sbjct: 322  LLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAH 381

Query: 310  LQLFIYCAEDL-----------------HLKKHQSVNPQLEVELIGEKLRTHMQTQTDNP 352
              L ++ AEDL                    K   V+P +EV   G+ L + +  +T NP
Sbjct: 382  FCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANP 441

Query: 353  IWNQILTFRIQLPCLSSYIKFRVLDCRKKDCPDEIGTASLSLNQISSTGEEIEGKQS--L 410
             WNQ +T     P +   ++ R++D  +    D + T  LS+++IS+ G EIE + +  +
Sbjct: 442  QWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEEEPAGAV 501

Query: 411  EPTSYTPRV-YSGFLPCFGPSFLTLHGGKKAPFRIQEEGACIPDSVRDGLAYRGRVFLEL 469
            +P+  +    Y GFLP FGP ++ L+G  +      +    +     +G+AYRGR+ L L
Sbjct: 502  KPSKASDLDDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSL 561

Query: 470  ITQIKSYQDSTIKDL-SHEVTRIEKHQNRQKYGLCVIFLSCTMMPNFKELIHFEVSIGHY 528
             T++  + +  ++DL + ++ R+EK+  R+KY L   F S TM+ +  + I FEVSIG+Y
Sbjct: 562  ETKLVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNY 621

Query: 529  GNKMDLNYKPLVSSTPYSPVIYDGNIYHYVPWYNTKPVVAVTSNWEDVSFRMNCLNLLHF 588
            GNK D+   PL S+T YS  ++DG  Y+Y+PW N KPVV ++S WED+S R+   N L  
Sbjct: 622  GNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLG 681

Query: 589  TRDRLKANLD----TLKSTRNPKDPALLYQWEKLLRELAEDCKRPLPCMTYQPKATSLDR 644
              DRL+A L+     LK+  + +D   L    +L  EL   C +PL  +   P AT LD+
Sbjct: 682  IADRLEAGLEQVHLALKAQCSTEDVDSLVA--QLTDELIAGCSQPLGDIHETPSATHLDQ 739

Query: 645  KRWQLRSLLLQE-----LAQKAKQAKPKDMVATAEDWLYRLNTVLPEPQMGLPDVMIWLV 699
              +QLR+  L +     LA K   ++    +  AEDWL RL  +  EPQ  LPD++IW++
Sbjct: 740  YLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWML 799

Query: 700  AKEQRVAYAQVPAHSVLFSPAGALHSGRLCGKIQTLFLQYPEGEGQKDVLPAHLRVCMWL 759
              ++RVAY +VPAH VLFS  GA + G+ CGK+QT+FL+YP  +     +P  +RV +W 
Sbjct: 800  QGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWF 859

Query: 760  GNVTDSKDLQLLRQGDTAVYAEMYENQAKYK--DQWGQQGLYHCPNFSDVMGNKTLPMTD 817
            G   D K+     +G  +V+AE YEN+ K      WG  GL + P FSDV G   LP   
Sbjct: 860  GLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTTGLTY-PKFSDVTGKIKLPKDS 918

Query: 818  FQPPLGWHWQDSWTVEPQRRLLLDIDINKSQVLEEVYENQGRDTRGAWGPAAIPNTDVNG 877
            F+P  GW W   W V P++ LL D+D      +EEV+ENQ R   G W   +   TDVNG
Sbjct: 919  FRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNG 978

Query: 878  QPMEARENVKCPQGWHFK-KDWVVELNHAVDS--WEYGVGIPPSGLPQVWSPVEKTYHSC 934
            + +  +++++CP GW ++ ++W  +LN AVD   WEY + IPP   P+ W P EK Y++ 
Sbjct: 979  EKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTH 1038

Query: 935  RRRRWARVRFRNHGELS----HEQETLSFLQLGLAKGEEEGWEYDT-FGSKFHLNPQPQS 989
            RRRRW R+R R+  ++     H Q          A+ E EGWEY + FG KFHL  +   
Sbjct: 1039 RRRRWVRLRRRDLSQMEALKRHRQ----------AEAEGEGWEYASLFGWKFHLEYRKTD 1088

Query: 990  RFRRRCWRRRLAPNKDKGIAPIFLLEGSLACEGGSVREEGDWAWARGNRSSTQEPQGRLS 1049
             FRRR WRRR+ P +  G A +F LEG+L    G V ++                     
Sbjct: 1089 AFRRRRWRRRMEPLEKTGPAAVFALEGAL----GGVMDD--------------------- 1123

Query: 1050 WVQAMDLKYHAGKEEDS---KTWPWGLDRQFRDPQRQDTRPPNLPFIYCTFNKPHYYQLF 1106
                        K EDS    T  +G++R               P I C F+  + Y L 
Sbjct: 1124 ------------KSEDSMSVSTLSFGVNR---------------PTISCIFDYGNRYHLR 1156

Query: 1107 CYIYQARNLVSNQILTFQGPFIRVVFLNHSQCTQTLRSSAGPTWAQTLIFQHLLLYENPQ 1166
            CY+YQAR+L +    +F  P+  V FL+ SQ T  ++++  PTW QTLIF  + ++  P 
Sbjct: 1157 CYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPA 1216

Query: 1167 DTKESPPLVVLELWQRDFWGKESLWGRSVWPPMVWLDLQDRILPPMRWHPLVKELGKEEG 1226
               E PP +V+EL+  D +G +   GR +  P +        +P + W PL +   +  G
Sbjct: 1217 TVAEQPPSIVVELYDHDTYGADEFMGRCICQPSL------ERMPRLAWFPLTRG-SQPSG 1269

Query: 1227 EILASCELILQTEKLGEKQLPILSV---------------PW-----KNGAYTLPKSIQP 1266
            E+LAS ELI Q EK     +P   V               P+     +   Y +P++I+P
Sbjct: 1270 ELLASFELI-QREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKP 1328

Query: 1267 TIKRMAIEILAWGLRNMKK-----ASSPQLLVEFGEESLRTEPIRDFQTNPNFPESESVL 1321
             ++R AIEILAWGLRNMK       SSP L+VE G +++++  IR+ + NPNF      L
Sbjct: 1329 ALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPNF--DICTL 1386

Query: 1322 VLTVLMPTEEAYALPLVVKVVDNWAFGQQTVTGQANIDFLQPYFCDPWAQDYMHPK---- 1377
             + V++P EE Y  P+ VKV+DN  FG++ V GQ  I  L+ + CDP++ +   P+    
Sbjct: 1387 FMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPD 1446

Query: 1378 -----------LPTLSEKKH------QDFLGYLYRKFWFK--SSKAEDEYEHEVDWWSKL 1418
                       L  + +K+        D L  L         SS  E+E+   +DWWSK 
Sbjct: 1447 DVSLLSPGEDVLIDIDDKEPLIPIQLADGLSSLAPTNTASPPSSPHEEEF---IDWWSKF 1503

Query: 1419 FWATDEHKSL-KYKYKDYHTLKVYECELEAVPAFQGLQDFCQTFKLYQ---EQPKLDSPV 1474
            F +  E +    Y  KD+ TLKVY+ +LE V AF+GL DFC TFKLY+   ++   D  V
Sbjct: 1504 FASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSV 1563

Query: 1475 VGEFKGLFRIYPFPENPEAPKPPLQFLVWPEREDFPQPCLVRVYMVRAINLQPQDYNGLC 1534
            +GEFKGLF+IYP PE+P  P PP QF     +   PQ CLVR+Y+VRA  LQP+D NG C
Sbjct: 1564 IGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQG--PQECLVRIYIVRAFGLQPKDPNGKC 1621

Query: 1535 DPYVILKLGKTELGNRDMYQPNTLDPIFGMMFELTCNIPLEKDLEIQLYDFDLFSPDDKI 1594
            DPY+ + +GK  + ++D Y P TL+P+FG MFELTC +PLEKDL+I LYD+DL S D+KI
Sbjct: 1622 DPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKI 1681

Query: 1595 GTTVIDLENRLLSGFGAHCGLSKSYCQSGPFRWRDQMPPSYLLERYAKRKGLPPPLFSPE 1654
            G TV+DLENRLLS FGA CGL ++YC SGP +WRDQ+ PS LL  + ++  +  P++   
Sbjct: 1682 GETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVY--R 1739

Query: 1655 EDAVFYNGKKFKLQSFEP-KTPTVHGLGPKKERLALYLLHTQGLVPEHVETRTLYSHSQP 1713
             D V +  K++ ++  E  + P  H LGP +ERLAL++L  QGLVPEHVE+R LYS  QP
Sbjct: 1740 TDRVMFQDKEYSIEEIEAGRIPNPH-LGPVEERLALHVLQQQGLVPEHVESRPLYSPLQP 1798

Query: 1714 GIDQGKVQMWVDIFPKKLGPPGPQVNINPRKPKRKASEHSGHRYELRCIIWKTANVDLVD 1773
             I+QGK+QMWVD+FPK LG PGP  NI PR+ +         R+ LRCIIW T +V L D
Sbjct: 1799 DIEQGKLQMWVDLFPKALGRPGPPFNITPRRAR---------RFFLRCIIWNTRDVILDD 1849

Query: 1774 DNLSREKTSDIYIKGWLYGLEKDMQKTDIHYHSLTGEADFNWRFIFTMDYLAAERTCVQS 1833
             +L+ EK SDIY+KGW+ G E+  QKTD+HY SL GE +FNWRFIF  DYL AE+ C  +
Sbjct: 1850 LSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIA 1909

Query: 1834 QKDYIWSLDATSMKFPARLIIQVWDNDIFSPDDFLGVLELDLSDMPLPARHAKQCSIRMM 1893
            +KD  W LD T  K PAR++ Q+WDND FS DDFLG L+LDL+ MP PA+ AK+CS+  +
Sbjct: 1910 KKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQL 1969

Query: 1894 D--ADPKWPYFIQYKHFSLFKKKTVTGWWPCQVLDGGKWRLSGKVKMSLEILSEKEALIK 1951
            D    P+W         SLF++KTV GWWPC   +G K  L+GK++M+LEI++E E   +
Sbjct: 1970 DDAFHPEW-------FVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEER 2022

Query: 1952 PAGRGQSEPNQYPTLHPPLRTNTSFTWLRSPVQNFCYIFWKRYRFKLIAFMVISIIALML 2011
            PAG+G+ EPN  P L  P R +TSF W  SP +   +I W+R+R+ +I F+++ I+ L L
Sbjct: 2023 PAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFL 2082

Query: 2012 FNFIYSAPHYLAMSWIKP 2029
              FIY+ P+Y AM  +KP
Sbjct: 2083 AIFIYAFPNYAAMKLVKP 2100



 Score = 40.0 bits (92), Expect = 0.024
 Identities = 24/86 (27%), Positives = 46/86 (53%), Gaps = 1/86 (1%)

Query: 20  RPCMSIDFRDIKKRTRVVEGNDPVWNETLIWHLWNRPLE-NDSFLQVTLQDMGSQKKERF 78
           +P + +      KRTR+ +GN P++NETL ++L++ P E  D  + +T+ D  S + +  
Sbjct: 239 KPVVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDAL 298

Query: 79  IGLATVLLKPLLKQPSEVLFVKDLTL 104
           +G   + +  + ++P      K L L
Sbjct: 299 LGEFRMDVGTIYREPRHAYLRKWLLL 324


>gi|195976773 dysferlin isoform 5 [Homo sapiens]
          Length = 2088

 Score = 1437 bits (3720), Expect = 0.0
 Identities = 857/2175 (39%), Positives = 1209/2175 (55%), Gaps = 277/2175 (12%)

Query: 21   PCMSIDFRDIKKRTRVVEGN-DPVWNETLIWHLWNRPLENDSFLQVTLQDMGSQKKERFI 79
            P  S+ FR +KKRT+V++ + +PVWNE   W L   PL+  S L V ++D  +  + RF+
Sbjct: 23   PVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLDQGSELHVVVKDHETMGRNRFL 82

Query: 80   GLATVLLKPLLKQPSEVLFVKDLTLLNHSMKPTDCTVTLQVAH----------------- 122
            G A V L+ +L  PS +    +  LL+   +PT  ++ LQV++                 
Sbjct: 83   GEAKVPLREVLATPS-LSASFNAPLLDTKKQPTGASLVLQVSYTPLPGAVPLFPPPTPLE 141

Query: 123  ----MSNQDI-EKTGAEDHL---GITAREA--------------ASQKLM------VPG- 153
                + + D+   TG E+     G+T  EA                +KL        PG 
Sbjct: 142  PSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGI 201

Query: 154  ------STAHRALSSKPQHFQVRVKVFEARQLMGNNIKPVVKVSIAGQQHQTRIKMGNNP 207
                   T+ + LS KPQ FQ+RV+V E RQL G NIKPVVKV+ AGQ  +TRI  GN+P
Sbjct: 202  KRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSP 261

Query: 208  FFNEIFFQNFHEVPAKFFDETILI-----------------QTDIGFIYHSPGHTLLRKW 250
             FNE  F N  + P + FDE I I                 + D+G IY  P H  LRKW
Sbjct: 262  LFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKW 321

Query: 251  LGLCQPNNPGSGVTGYLKVTIYALGVGDQALIDQK-LLYGTDDTDIQIFKSAVVPINMAY 309
            L L  P++  +G  GYLK ++  LG GD+A +++K      +D +  + +   V +  A+
Sbjct: 322  LLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAH 381

Query: 310  LQLFIYCAEDL-----------------HLKKHQSVNPQLEVELIGEKLRTHMQTQTDNP 352
              L ++ AEDL                    K   V+P +EV   G+ L + +  +T NP
Sbjct: 382  FCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANP 441

Query: 353  IWNQILTFRIQLPCLSSYIKFRVLDCRKKDCPDEIGTASLSLNQISSTGEEIEGKQSLEP 412
             WNQ +T     P +   ++ R++D  +    D + T  LS+++IS+ G EIE       
Sbjct: 442  QWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEVDD---- 497

Query: 413  TSYTPRVYSGFLPCFGPSFLTLHGGKKAPFRIQEEGACIPDSVRDGLAYRGRVFLELITQ 472
                   Y GFLP FGP ++ L+G  +      +    +     +G+AYRGR+ L L T+
Sbjct: 498  -------YLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETK 550

Query: 473  IKSYQDSTIKDL-SHEVTRIEKHQNRQKYGLCVIFLSCTMMPNFKELIHFEVSIGHYGNK 531
            +  + +  ++DL + ++ R+EK+  R+KY L   F S TM+ +  + I FEVSIG+YGNK
Sbjct: 551  LVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNK 610

Query: 532  MDLNYKPLVSSTPYSPVIYDGNIYHYVPWYNTKPVVAVTSNWEDVSFRMNCLNLLHFTRD 591
             D+   PL S+T YS  ++DG  Y+Y+PW N KPVV ++S WED+S R+   N L    D
Sbjct: 611  FDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIAD 670

Query: 592  RLKANLD----TLKSTRNPKDPALLYQWEKLLRELAEDCKRPLPCMTYQPKATSLDRKRW 647
            RL+A L+     LK+  + +D   L    +L  EL   C +PL  +   P AT LD+  +
Sbjct: 671  RLEAGLEQVHLALKAQCSTEDVDSLVA--QLTDELIAGCSQPLGDIHETPSATHLDQYLY 728

Query: 648  QLRSLLLQE-----LAQKAKQAKPKDMVATAEDWLYRLNTVLPEPQMGLPDVMIWLVAKE 702
            QLR+  L +     LA K   ++    +  AEDWL RL  +  EPQ  LPD++IW++  +
Sbjct: 729  QLRTHHLSQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGD 788

Query: 703  QRVAYAQVPAHSVLFSPAGALHSGRLCGKIQTLFLQYPEGEGQKDVLPAHLRVCMWLGNV 762
            +RVAY +VPAH VLFS  GA + G+ CGK+QT+FL+YP  +     +P  +RV +W G  
Sbjct: 789  KRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLS 848

Query: 763  TDSKDLQLLRQGDTAVYAEMYENQAKYK--DQWGQQGLYHCPNFSDVMGNKTLPMTDFQP 820
             D K+     +G  +V+AE YEN+ K      WG  GL + P FSDV G   LP   F+P
Sbjct: 849  VDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTTGLTY-PKFSDVTGKIKLPKDSFRP 907

Query: 821  PLGWHWQDSWTVEPQRRLLLDIDINKSQVLEEVYENQGRDTRGAWGPAAIPNTDVNGQPM 880
              GW W   W V P++ LL D+D      +EEV+ENQ R   G W   +   TDVNG+ +
Sbjct: 908  SAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKV 967

Query: 881  EARENVKCPQGWHFK-KDWVVELNHAVDS--WEYGVGIPPSGLPQVWSPVEKTYHSCRRR 937
              +++++CP GW ++ ++W  +LN AVD   WEY + IPP   P+ W P EK Y++ RRR
Sbjct: 968  LPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRR 1027

Query: 938  RWARVRFRNHGELS----HEQETLSFLQLGLAKGEEEGWEYDT-FGSKFHLNPQPQSRFR 992
            RW R+R R+  ++     H Q          A+ E EGWEY + FG KFHL  +    FR
Sbjct: 1028 RWVRLRRRDLSQMEALKRHRQ----------AEAEGEGWEYASLFGWKFHLEYRKTDAFR 1077

Query: 993  RRCWRRRLAPNKDKGIAPIFLLEGSLACEGGSVREEGDWAWARGNRSSTQEPQGRLSWVQ 1052
            RR WRRR+ P +  G A +F LEG+L    G V ++                        
Sbjct: 1078 RRRWRRRMEPLEKTGPAAVFALEGAL----GGVMDD------------------------ 1109

Query: 1053 AMDLKYHAGKEEDS---KTWPWGLDRQFRDPQRQDTRPPNLPFIYCTFNKPHYYQLFCYI 1109
                     K EDS    T  +G++R               P I C F+  + Y L CY+
Sbjct: 1110 ---------KSEDSMSVSTLSFGVNR---------------PTISCIFDYGNRYHLRCYM 1145

Query: 1110 YQARNLVSNQILTFQGPFIRVVFLNHSQCTQTLRSSAGPTWAQTLIFQHLLLYENPQDTK 1169
            YQAR+L +    +F  P+  V FL+ SQ T  ++++  PTW QTLIF  + ++  P    
Sbjct: 1146 YQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVA 1205

Query: 1170 ESPPLVVLELWQRDFWGKESLWGRSVWPPMVWLDLQDRILPPMRWHPLVKELGKEEGEIL 1229
            E PP +V+EL+  D +G +   GR +  P +        +P + W PL +   +  GE+L
Sbjct: 1206 EQPPSIVVELYDHDTYGADEFMGRCICQPSL------ERMPRLAWFPLTRG-SQPSGELL 1258

Query: 1230 ASCELILQTEKLGEKQLPILSV---------------PW-----KNGAYTLPKSIQPTIK 1269
            AS ELI Q EK     +P   V               P+     +   Y +P++I+P ++
Sbjct: 1259 ASFELI-QREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQ 1317

Query: 1270 RMAIEILAWGLRNMKK-----ASSPQLLVEFGEESLRTEPIRDFQTNPNFPESESVLVLT 1324
            R AIEILAWGLRNMK       SSP L+VE G +++++  IR+ + NPNF      L + 
Sbjct: 1318 RTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPNF--DICTLFME 1375

Query: 1325 VLMPTEEAYALPLVVKVVDNWAFGQQTVTGQANIDFLQPYFCDPWAQDYMHPK------- 1377
            V++P EE Y  P+ VKV+DN  FG++ V GQ  I  L+ + CDP++ +   P+       
Sbjct: 1376 VMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVS 1435

Query: 1378 --------LPTLSEKKH------QDFLGYLYRKFWFK--SSKAEDEYEHEVDWWSKLFWA 1421
                    L  + +K+        D L  L         SS  E+E+   +DWWSK F +
Sbjct: 1436 LLSPGEDVLIDIDDKEPLIPIQLADGLSSLAPTNTASPPSSPHEEEF---IDWWSKFFAS 1492

Query: 1422 TDEHKSL-KYKYKDYHTLKVYECELEAVPAFQGLQDFCQTFKLYQ---EQPKLDSPVVGE 1477
              E +    Y  KD+ TLKVY+ +LE V AF+GL DFC TFKLY+   ++   D  V+GE
Sbjct: 1493 IGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGE 1552

Query: 1478 FKGLFRIYPFPENPEAPKPPLQFLVWPEREDFPQPCLVRVYMVRAINLQPQDYNGLCDPY 1537
            FKGLF+IYP PE+P  P PP QF     +   PQ CLVR+Y+VRA  LQP+D NG CDPY
Sbjct: 1553 FKGLFKIYPLPEDPAIPMPPRQFHQLAAQG--PQECLVRIYIVRAFGLQPKDPNGKCDPY 1610

Query: 1538 VILKLGKTELGNRDMYQPNTLDPIFGMMFELTCNIPLEKDLEIQLYDFDLFSPDDKIGTT 1597
            + + +GK  + ++D Y P TL+P+FG MFELTC +PLEKDL+I LYD+DL S D+KIG T
Sbjct: 1611 IKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGET 1670

Query: 1598 VIDLENRLLSGFGAHCGLSKSYCQSGPFRWRDQMPPSYLLERYAKRKGLPPPLFSPEEDA 1657
            V+DLENRLLS FGA CGL ++YC SGP +WRDQ+ PS LL  + ++  +  P++    D 
Sbjct: 1671 VVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVY--RTDR 1728

Query: 1658 VFYNGKKFKLQSFEP-KTPTVHGLGPKKERLALYLLHTQGLVPEHVETRTLYSHSQPGID 1716
            V +  K++ ++  E  + P  H LGP +ERLAL++L  QGLVPEHVE+R LYS  QP I+
Sbjct: 1729 VMFQDKEYSIEEIEAGRIPNPH-LGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDIE 1787

Query: 1717 QGKVQMWVDIFPKKLGPPGPQVNINPRKPKRKASEHSGHRYELRCIIWKTANVDLVDDNL 1776
            QGK+QMWVD+FPK LG PGP  NI PR+ +         R+ LRCIIW T +V L D +L
Sbjct: 1788 QGKLQMWVDLFPKALGRPGPPFNITPRRAR---------RFFLRCIIWNTRDVILDDLSL 1838

Query: 1777 SREKTSDIYIKGWLYGLEKDMQKTDIHYHSLTGEADFNWRFIFTMDYLAAERTCVQSQKD 1836
            + EK SDIY+KGW+ G E+  QKTD+HY SL GE +FNWRFIF  DYL AE+ C  ++KD
Sbjct: 1839 TGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKD 1898

Query: 1837 YIWSLDATSMKFPARLIIQVWDNDIFSPDDFLGVLELDLSDMPLPARHAKQCSIRMMD-- 1894
              W LD T  K PAR++ Q+WDND FS DDFLG L+LDL+ MP PA+ AK+CS+  +D  
Sbjct: 1899 AFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDA 1958

Query: 1895 ADPKWPYFIQYKHFSLFKKKTVTGWWPCQVLDGGKWRLSGKVKMSLEILSEKEALIKPAG 1954
              P+W         SLF++KTV GWWPC   +G K  L+GK++M+LEI++E E   +PAG
Sbjct: 1959 FHPEW-------FVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAG 2011

Query: 1955 RGQSEPNQYPTLHPPLRTNTSFTWLRSPVQNFCYIFWKRYRFKLIAFMVISIIALMLFNF 2014
            +G+ EPN  P L  P R +TSF W  SP +   +I W+R+R+ +I F+++ I+ L L  F
Sbjct: 2012 QGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIF 2071

Query: 2015 IYSAPHYLAMSWIKP 2029
            IY+ P+Y AM  +KP
Sbjct: 2072 IYAFPNYAAMKLVKP 2086



 Score = 40.0 bits (92), Expect = 0.024
 Identities = 24/86 (27%), Positives = 46/86 (53%), Gaps = 1/86 (1%)

Query: 20  RPCMSIDFRDIKKRTRVVEGNDPVWNETLIWHLWNRPLE-NDSFLQVTLQDMGSQKKERF 78
           +P + +      KRTR+ +GN P++NETL ++L++ P E  D  + +T+ D  S + +  
Sbjct: 239 KPVVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDAL 298

Query: 79  IGLATVLLKPLLKQPSEVLFVKDLTL 104
           +G   + +  + ++P      K L L
Sbjct: 299 LGEFRMDVGTIYREPRHAYLRKWLLL 324


>gi|4503431 dysferlin isoform 8 [Homo sapiens]
          Length = 2080

 Score = 1436 bits (3717), Expect = 0.0
 Identities = 858/2181 (39%), Positives = 1219/2181 (55%), Gaps = 255/2181 (11%)

Query: 1    MLRLVVQSAK-IDPPLAPLPRPCMSIDFRDIKKRTRVVEGN-DPVWNETLIWHLWNRPLE 58
            MLR+ +  A+ +  P   +     S  F  +KKRT+V++ + +PVWNE   W L   PL+
Sbjct: 1    MLRVFILYAENVHTPDTDISDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLD 60

Query: 59   NDSFLQVTLQDMGSQKKERFIGLATVLLKPLLKQPSEVLFVKDLTLLNHSMKPTDCTVTL 118
              S L V ++D  +  + RF+G A V L+ +L  PS +    +  LL+   +PT  ++ L
Sbjct: 61   QGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPS-LSASFNAPLLDTKKQPTGASLVL 119

Query: 119  QVAH---------------------MSNQDI-EKTGAEDHL---GITAREA--------- 144
            QV++                     + + D+   TG E+     G+T  EA         
Sbjct: 120  QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGG 179

Query: 145  -----ASQKLM------VPG-------STAHRALSSKPQHFQVRVKVFEARQLMGNNIKP 186
                   +KL        PG        T+ + LS KPQ FQ+RV+V E RQL G NIKP
Sbjct: 180  PGAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKP 239

Query: 187  VVKVSIAGQQHQTRIKMGNNPFFNEIFFQNFHEVPAKFFDETILI--------------- 231
            VVKV+ AGQ  +TRI  GN+P FNE  F N  + P + FDE I I               
Sbjct: 240  VVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLG 299

Query: 232  --QTDIGFIYHSPGHTLLRKWLGLCQPNNPGSGVTGYLKVTIYALGVGDQALIDQK-LLY 288
              + D+G IY  P H  LRKWL L  P++  +G  GYLK ++  LG GD+A +++K    
Sbjct: 300  EFRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSE 359

Query: 289  GTDDTDIQIFKSAVVPINMAYLQLFIYCAEDL-----------------HLKKHQSVNPQ 331
              +D +  + +   V +  A+  L ++ AEDL                    K   V+P 
Sbjct: 360  DKEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPF 419

Query: 332  LEVELIGEKLRTHMQTQTDNPIWNQILTFRIQLPCLSSYIKFRVLDCRKKDCPDEIGTAS 391
            +EV   G+ L + +  +T NP WNQ +T     P +   ++ R++D  +    D + T  
Sbjct: 420  VEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTY 479

Query: 392  LSLNQISSTGEEIEGKQS--LEPTSYTPRV-YSGFLPCFGPSFLTLHGGKKAPFRIQEEG 448
            LS+++IS+ G EIE + +  ++P+  +    Y GFLP FGP ++ L+G  +      +  
Sbjct: 480  LSMSKISAPGGEIEEEPAGAVKPSKASDLDDYLGFLPTFGPCYINLYGSPREFTGFPDPY 539

Query: 449  ACIPDSVRDGLAYRGRVFLELITQIKSYQDSTIKDL-SHEVTRIEKHQNRQKYGLCVIFL 507
              +     +G+AYRGR+ L L T++  + +  ++DL + ++ R+EK+  R+KY L   F 
Sbjct: 540  TELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFY 599

Query: 508  SCTMMPNFKELIHFEVSIGHYGNKMDLNYKPLVSSTPYSPVIYDGNIYHYVPWYNTKPVV 567
            S TM+ +  + I FEVSIG+YGNK D+   PL S+T YS  ++DG  Y+Y+PW N KPVV
Sbjct: 600  SATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVV 659

Query: 568  AVTSNWEDVSFRMNCLNLLHFTRDRLKANLD----TLKSTRNPKDPALLYQWEKLLRELA 623
             ++S WED+S R+   N L    DRL+A L+     LK+  + +D   L    +L  EL 
Sbjct: 660  VLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVA--QLTDELI 717

Query: 624  EDCKRPLPCMTYQPKATSLDRKRWQLRSLLLQE-----LAQKAKQAKPKDMVATAEDWLY 678
              C +PL  +   P AT LD+  +QLR+  L +     LA K   ++    +  AEDWL 
Sbjct: 718  AGCSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWLL 777

Query: 679  RLNTVLPEPQMGLPDVMIWLVAKEQRVAYAQVPAHSVLFSPAGALHSGRLCGKIQTLFLQ 738
            RL  +  EPQ  LPD++IW++  ++RVAY +VPAH VLFS  GA + G+ CGK+QT+FL+
Sbjct: 778  RLRALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLK 837

Query: 739  YPEGEGQKDVLPAHLRVCMWLGNVTDSKDLQLLRQGDTAVYAEMYENQAKYK--DQWGQQ 796
            YP  +     +P  +RV +W G   D K+     +G  +V+AE YEN+ K      WG  
Sbjct: 838  YPMEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTT 897

Query: 797  GLYHCPNFSDVMGNKTLPMTDFQPPLGWHWQDSWTVEPQRRLLLDIDINKSQVLEEVYEN 856
            GL + P FSDV G   LP   F+P  GW W   W V P++ LL D+D      +EEV+EN
Sbjct: 898  GLTY-PKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFEN 956

Query: 857  QGRDTRGAWGPAAIPNTDVNGQPMEARENVKCPQGWHFK-KDWVVELNHAVDS--WEYGV 913
            Q R   G W   +   TDVNG+ +  +++++CP GW ++ ++W  +LN AVD   WEY +
Sbjct: 957  QTRLPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSI 1016

Query: 914  GIPPSGLPQVWSPVEKTYHSCRRRRWARVRFRNHGELS----HEQETLSFLQLGLAKGEE 969
             IPP   P+ W P EK Y++ RRRRW R+R R+  ++     H Q          A+ E 
Sbjct: 1017 TIPPERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQ----------AEAEG 1066

Query: 970  EGWEYDT-FGSKFHLNPQPQSRFRRRCWRRRLAPNKDKGIAPIFLLEGSLACEGGSVREE 1028
            EGWEY + FG KFHL  +    FRRR WRRR+ P +  G A +F LEG+L    G V ++
Sbjct: 1067 EGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGAL----GGVMDD 1122

Query: 1029 GDWAWARGNRSSTQEPQGRLSWVQAMDLKYHAGKEEDS---KTWPWGLDRQFRDPQRQDT 1085
                                             K EDS    T  +G++R          
Sbjct: 1123 ---------------------------------KSEDSMSVSTLSFGVNR---------- 1139

Query: 1086 RPPNLPFIYCTFNKPHYYQLFCYIYQARNLVSNQILTFQGPFIRVVFLNHSQCTQTLRSS 1145
                 P I C F+  + Y L CY+YQAR+L +    +F  P+  V FL+ SQ T  ++++
Sbjct: 1140 -----PTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNT 1194

Query: 1146 AGPTWAQTLIFQHLLLYENPQDTKESPPLVVLELWQRDFWGKESLWGRSVWPPMVWLDLQ 1205
              PTW QTLIF  + ++  P    E PP +V+EL+  D +G +   GR +  P +     
Sbjct: 1195 LNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSL----- 1249

Query: 1206 DRILPPMRWHPLVKELGKEEGEILASCELILQTEKLGEKQLPILSV-------------- 1251
               +P + W PL +   +  GE+LAS ELI Q EK     +P   V              
Sbjct: 1250 -ERMPRLAWFPLTRG-SQPSGELLASFELI-QREKPAIHHIPGFEVQETSRILDESEDTD 1306

Query: 1252 -PW-----KNGAYTLPKSIQPTIKRMAIEILAWGLRNMKK-----ASSPQLLVEFGEESL 1300
             P+     +   Y +P++I+P ++R AIEILAWGLRNMK       SSP L+VE G +++
Sbjct: 1307 LPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTV 1366

Query: 1301 RTEPIRDFQTNPNFPESESVLVLTVLMPTEEAYALPLVVKVVDNWAFGQQTVTGQANIDF 1360
            ++  IR+ + NPNF      L + V++P EE Y  P+ VKV+DN  FG++ V GQ  I  
Sbjct: 1367 QSCVIRNLRKNPNF--DICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRS 1424

Query: 1361 LQPYFCDPWAQDYMHPK-----LPTLSEKKHQDFLGYLYRKFWFKSSKAEDEYEHEVDWW 1415
            L+ + CDP++ +   P+     +  LS    +D L  +  K          + E  +DWW
Sbjct: 1425 LESFLCDPYSAESPSPQGGPDDVSLLSPG--EDVLIDIDDK----EPLIPIQEEEFIDWW 1478

Query: 1416 SKLFWATDEHKSL-KYKYKDYHTLKVYECELEAVPAFQGLQDFCQTFKLYQ---EQPKLD 1471
            SK F +  E +    Y  KD+ TLKVY+ +LE V AF+GL DFC TFKLY+   ++   D
Sbjct: 1479 SKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETED 1538

Query: 1472 SPVVGEFKGLFRIYPFPENPEAPKPPLQFLVWPEREDFPQPCLVRVYMVRAINLQPQDYN 1531
              V+GEFKGLF+IYP PE+P  P PP QF     +   PQ CLVR+Y+VRA  LQP+D N
Sbjct: 1539 PSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQG--PQECLVRIYIVRAFGLQPKDPN 1596

Query: 1532 GLCDPYVILKLGKTELGNRDMYQPNTLDPIFGMMFELTCNIPLEKDLEIQLYDFDLFSPD 1591
            G CDPY+ + +GK  + ++D Y P TL+P+FG MFELTC +PLEKDL+I LYD+DL S D
Sbjct: 1597 GKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKD 1656

Query: 1592 DKIGTTVIDLENRLLSGFGAHCGLSKSYCQSGPFRWRDQMPPSYLLERYAKRKGLPPPLF 1651
            +KIG TV+DLENRLLS FGA CGL ++YC SGP +WRDQ+ PS LL  + ++  +  P++
Sbjct: 1657 EKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVY 1716

Query: 1652 SPEEDAVFYNGKKFKLQSFEP-KTPTVHGLGPKKERLALYLLHTQGLVPEHVETRTLYSH 1710
                D V +  K++ ++  E  + P  H LGP +ERLAL++L  QGLVPEHVE+R LYS 
Sbjct: 1717 --RTDRVMFQDKEYSIEEIEAGRIPNPH-LGPVEERLALHVLQQQGLVPEHVESRPLYSP 1773

Query: 1711 SQPGIDQGKVQMWVDIFPKKLGPPGPQVNINPRKPKRKASEHSGHRYELRCIIWKTANVD 1770
             QP I+QGK+QMWVD+FPK LG PGP  NI PR+ +         R+ LRCIIW T +V 
Sbjct: 1774 LQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRAR---------RFFLRCIIWNTRDVI 1824

Query: 1771 LVDDNLSREKTSDIYIKGWLYGLEKDMQKTDIHYHSLTGEADFNWRFIFTMDYLAAERTC 1830
            L D +L+ EK SDIY+KGW+ G E+  QKTD+HY SL GE +FNWRFIF  DYL AE+ C
Sbjct: 1825 LDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVC 1884

Query: 1831 VQSQKDYIWSLDATSMKFPARLIIQVWDNDIFSPDDFLGVLELDLSDMPLPARHAKQCSI 1890
              ++KD  W LD T  K PAR++ Q+WDND FS DDFLG L+LDL+ MP PA+ AK+CS+
Sbjct: 1885 TIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSL 1944

Query: 1891 RMMD--ADPKWPYFIQYKHFSLFKKKTVTGWWPCQVLDGGKWRLSGKVKMSLEILSEKEA 1948
              +D    P+W         SLF++KTV GWWPC   +G K  L+GK++M+LEI++E E 
Sbjct: 1945 DQLDDAFHPEW-------FVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEH 1997

Query: 1949 LIKPAGRGQSEPNQYPTLHPPLRTNTSFTWLRSPVQNFCYIFWKRYRFKLIAFMVISIIA 2008
              +PAG+G+ EPN  P L  P R +TSF W  SP +   +I W+R+R+ +I F+++ I+ 
Sbjct: 1998 EERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILL 2057

Query: 2009 LMLFNFIYSAPHYLAMSWIKP 2029
            L L  FIY+ P+Y AM  +KP
Sbjct: 2058 LFLAIFIYAFPNYAAMKLVKP 2078


>gi|195976754 dysferlin isoform 9 [Homo sapiens]
          Length = 2066

 Score = 1435 bits (3714), Expect = 0.0
 Identities = 857/2178 (39%), Positives = 1212/2178 (55%), Gaps = 263/2178 (12%)

Query: 1    MLRLVVQSAK-IDPPLAPLPRPCMSIDFRDIKKRTRVVEGN-DPVWNETLIWHLWNRPLE 58
            MLR+ +  A+ +  P   +     S  F  +KKRT+V++ + +PVWNE   W L   PL+
Sbjct: 1    MLRVFILYAENVHTPDTDISDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLD 60

Query: 59   NDSFLQVTLQDMGSQKKERFIGLATVLLKPLLKQPSEVLFVKDLTLLNHSMKPTDCTVTL 118
              S L V ++D  +  + RF+G A V L+ +L  PS +    +  LL+   +PT  ++ L
Sbjct: 61   QGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPS-LSASFNAPLLDTKKQPTGASLVL 119

Query: 119  QVAH---------------------MSNQDI-EKTGAEDHL---GITAREA--------- 144
            QV++                     + + D+   TG E+     G+T  EA         
Sbjct: 120  QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGG 179

Query: 145  -----ASQKLM------VPG-------STAHRALSSKPQHFQVRVKVFEARQLMGNNIKP 186
                   +KL        PG        T+ + LS KPQ FQ+RV+V E RQL G NIKP
Sbjct: 180  PGAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKP 239

Query: 187  VVKVSIAGQQHQTRIKMGNNPFFNEIFFQNFHEVPAKFFDETILI--------------- 231
            VVKV+ AGQ  +TRI  GN+P FNE  F N  + P + FDE I I               
Sbjct: 240  VVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLG 299

Query: 232  --QTDIGFIYHSPGHTLLRKWLGLCQPNNPGSGVTGYLKVTIYALGVGDQALIDQK-LLY 288
              + D+G IY  P H  LRKWL L  P++  +G  GYLK ++  LG GD+A +++K    
Sbjct: 300  EFRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSE 359

Query: 289  GTDDTDIQIFKSAVVPINMAYLQLFIYCAEDL-----------------HLKKHQSVNPQ 331
              +D +  + +   V +  A+  L ++ AEDL                    K   V+P 
Sbjct: 360  DKEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPF 419

Query: 332  LEVELIGEKLRTHMQTQTDNPIWNQILTFRIQLPCLSSYIKFRVLDCRKKDCPDEIGTAS 391
            +EV   G+ L + +  +T NP WNQ +T     P +   ++ R++D  +    D + T  
Sbjct: 420  VEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTY 479

Query: 392  LSLNQISSTGEEIEGKQSLEPTSYTPRVYSGFLPCFGPSFLTLHGGKKAPFRIQEEGACI 451
            LS+++IS+ G EIE              Y GFLP FGP ++ L+G  +      +    +
Sbjct: 480  LSMSKISAPGGEIEVDD-----------YLGFLPTFGPCYINLYGSPREFTGFPDPYTEL 528

Query: 452  PDSVRDGLAYRGRVFLELITQIKSYQDSTIKDL-SHEVTRIEKHQNRQKYGLCVIFLSCT 510
                 +G+AYRGR+ L L T++  + +  ++DL + ++ R+EK+  R+KY L   F S T
Sbjct: 529  NTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFYSAT 588

Query: 511  MMPNFKELIHFEVSIGHYGNKMDLNYKPLVSSTPYSPVIYDGNIYHYVPWYNTKPVVAVT 570
            M+ +  + I FEVSIG+YGNK D+   PL S+T YS  ++DG  Y+Y+PW N KPVV ++
Sbjct: 589  MLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLS 648

Query: 571  SNWEDVSFRMNCLNLLHFTRDRLKANLD----TLKSTRNPKDPALLYQWEKLLRELAEDC 626
            S WED+S R+   N L    DRL+A L+     LK+  + +D   L    +L  EL   C
Sbjct: 649  SYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVA--QLTDELIAGC 706

Query: 627  KRPLPCMTYQPKATSLDRKRWQLRSLLLQE-----LAQKAKQAKPKDMVATAEDWLYRLN 681
             +PL  +   P AT LD+  +QLR+  L +     LA K   ++    +  AEDWL RL 
Sbjct: 707  SQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWLLRLR 766

Query: 682  TVLPEPQMGLPDVMIWLVAKEQRVAYAQVPAHSVLFSPAGALHSGRLCGKIQTLFLQYPE 741
             +  EPQ  LPD++IW++  ++RVAY +VPAH VLFS  GA + G+ CGK+QT+FL+YP 
Sbjct: 767  ALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYPM 826

Query: 742  GEGQKDVLPAHLRVCMWLGNVTDSKDLQLLRQGDTAVYAEMYENQAKYK--DQWGQQGLY 799
             +     +P  +RV +W G   D K+     +G  +V+AE YEN+ K      WG  GL 
Sbjct: 827  EKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTTGLT 886

Query: 800  HCPNFSDVMGNKTLPMTDFQPPLGWHWQDSWTVEPQRRLLLDIDINKSQVLEEVYENQGR 859
            + P FSDV G   LP   F+P  GW W   W V P++ LL D+D      +EEV+ENQ R
Sbjct: 887  Y-PKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTR 945

Query: 860  DTRGAWGPAAIPNTDVNGQPMEARENVKCPQGWHFK-KDWVVELNHAVDS--WEYGVGIP 916
               G W   +   TDVNG+ +  +++++CP GW ++ ++W  +LN AVD   WEY + IP
Sbjct: 946  LPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIP 1005

Query: 917  PSGLPQVWSPVEKTYHSCRRRRWARVRFRNHGELS----HEQETLSFLQLGLAKGEEEGW 972
            P   P+ W P EK Y++ RRRRW R+R R+  ++     H Q          A+ E EGW
Sbjct: 1006 PERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQ----------AEAEGEGW 1055

Query: 973  EYDT-FGSKFHLNPQPQSRFRRRCWRRRLAPNKDKGIAPIFLLEGSLACEGGSVREEGDW 1031
            EY + FG KFHL  +    FRRR WRRR+ P +  G A +F LEG+L    G V ++   
Sbjct: 1056 EYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGAL----GGVMDD--- 1108

Query: 1032 AWARGNRSSTQEPQGRLSWVQAMDLKYHAGKEEDS---KTWPWGLDRQFRDPQRQDTRPP 1088
                                          K EDS    T  +G++R             
Sbjct: 1109 ------------------------------KSEDSMSVSTLSFGVNR------------- 1125

Query: 1089 NLPFIYCTFNKPHYYQLFCYIYQARNLVSNQILTFQGPFIRVVFLNHSQCTQTLRSSAGP 1148
              P I C F+  + Y L CY+YQAR+L +    +F  P+  V FL+ SQ T  ++++  P
Sbjct: 1126 --PTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNP 1183

Query: 1149 TWAQTLIFQHLLLYENPQDTKESPPLVVLELWQRDFWGKESLWGRSVWPPMVWLDLQDRI 1208
            TW QTLIF  + ++  P    E PP +V+EL+  D +G +   GR +  P +        
Sbjct: 1184 TWDQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSL------ER 1237

Query: 1209 LPPMRWHPLVKELGKEEGEILASCELILQTEKLGEKQLPILSV---------------PW 1253
            +P + W PL +   +  GE+LAS ELI Q EK     +P   V               P+
Sbjct: 1238 MPRLAWFPLTRG-SQPSGELLASFELI-QREKPAIHHIPGFEVQETSRILDESEDTDLPY 1295

Query: 1254 -----KNGAYTLPKSIQPTIKRMAIEILAWGLRNMKK-----ASSPQLLVEFGEESLRTE 1303
                 +   Y +P++I+P ++R AIEILAWGLRNMK       SSP L+VE G +++++ 
Sbjct: 1296 PPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTVQSC 1355

Query: 1304 PIRDFQTNPNFPESESVLVLTVLMPTEEAYALPLVVKVVDNWAFGQQTVTGQANIDFLQP 1363
             IR+ + NPNF      L + V++P EE Y  P+ VKV+DN  FG++ V GQ  I  L+ 
Sbjct: 1356 VIRNLRKNPNF--DICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLES 1413

Query: 1364 YFCDPWAQDYMHPK-----LPTLSEKKHQDFLGYLYRKFWFKSSKAEDEYEHEVDWWSKL 1418
            + CDP++ +   P+     +  LS    +D L  +  K          + E  +DWWSK 
Sbjct: 1414 FLCDPYSAESPSPQGGPDDVSLLSPG--EDVLIDIDDK----EPLIPIQEEEFIDWWSKF 1467

Query: 1419 FWATDEHKSL-KYKYKDYHTLKVYECELEAVPAFQGLQDFCQTFKLYQ---EQPKLDSPV 1474
            F +  E +    Y  KD+ TLKVY+ +LE V AF+GL DFC TFKLY+   ++   D  V
Sbjct: 1468 FASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSV 1527

Query: 1475 VGEFKGLFRIYPFPENPEAPKPPLQFLVWPEREDFPQPCLVRVYMVRAINLQPQDYNGLC 1534
            +GEFKGLF+IYP PE+P  P PP QF     +   PQ CLVR+Y+VRA  LQP+D NG C
Sbjct: 1528 IGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQG--PQECLVRIYIVRAFGLQPKDPNGKC 1585

Query: 1535 DPYVILKLGKTELGNRDMYQPNTLDPIFGMMFELTCNIPLEKDLEIQLYDFDLFSPDDKI 1594
            DPY+ + +GK  + ++D Y P TL+P+FG MFELTC +PLEKDL+I LYD+DL S D+KI
Sbjct: 1586 DPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKI 1645

Query: 1595 GTTVIDLENRLLSGFGAHCGLSKSYCQSGPFRWRDQMPPSYLLERYAKRKGLPPPLFSPE 1654
            G TV+DLENRLLS FGA CGL ++YC SGP +WRDQ+ PS LL  + ++  +  P++   
Sbjct: 1646 GETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVY--R 1703

Query: 1655 EDAVFYNGKKFKLQSFEP-KTPTVHGLGPKKERLALYLLHTQGLVPEHVETRTLYSHSQP 1713
             D V +  K++ ++  E  + P  H LGP +ERLAL++L  QGLVPEHVE+R LYS  QP
Sbjct: 1704 TDRVMFQDKEYSIEEIEAGRIPNPH-LGPVEERLALHVLQQQGLVPEHVESRPLYSPLQP 1762

Query: 1714 GIDQGKVQMWVDIFPKKLGPPGPQVNINPRKPKRKASEHSGHRYELRCIIWKTANVDLVD 1773
             I+QGK+QMWVD+FPK LG PGP  NI PR+ +         R+ LRCIIW T +V L D
Sbjct: 1763 DIEQGKLQMWVDLFPKALGRPGPPFNITPRRAR---------RFFLRCIIWNTRDVILDD 1813

Query: 1774 DNLSREKTSDIYIKGWLYGLEKDMQKTDIHYHSLTGEADFNWRFIFTMDYLAAERTCVQS 1833
             +L+ EK SDIY+KGW+ G E+  QKTD+HY SL GE +FNWRFIF  DYL AE+ C  +
Sbjct: 1814 LSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIA 1873

Query: 1834 QKDYIWSLDATSMKFPARLIIQVWDNDIFSPDDFLGVLELDLSDMPLPARHAKQCSIRMM 1893
            +KD  W LD T  K PAR++ Q+WDND FS DDFLG L+LDL+ MP PA+ AK+CS+  +
Sbjct: 1874 KKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQL 1933

Query: 1894 D--ADPKWPYFIQYKHFSLFKKKTVTGWWPCQVLDGGKWRLSGKVKMSLEILSEKEALIK 1951
            D    P+W         SLF++KTV GWWPC   +G K  L+GK++M+LEI++E E   +
Sbjct: 1934 DDAFHPEW-------FVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEER 1986

Query: 1952 PAGRGQSEPNQYPTLHPPLRTNTSFTWLRSPVQNFCYIFWKRYRFKLIAFMVISIIALML 2011
            PAG+G+ EPN  P L  P R +TSF W  SP +   +I W+R+R+ +I F+++ I+ L L
Sbjct: 1987 PAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFL 2046

Query: 2012 FNFIYSAPHYLAMSWIKP 2029
              FIY+ P+Y AM  +KP
Sbjct: 2047 AIFIYAFPNYAAMKLVKP 2064


>gi|195976758 dysferlin isoform 11 [Homo sapiens]
          Length = 2101

 Score = 1434 bits (3711), Expect = 0.0
 Identities = 861/2199 (39%), Positives = 1223/2199 (55%), Gaps = 270/2199 (12%)

Query: 1    MLRLVVQSAK-IDPPLAPLPRPCMSIDFRDIKKRTRVVEGN-DPVWNETLIWHLWNRPLE 58
            MLR+ +  A+ +  P   +     S  F  +KKRT+V++ + +PVWNE   W L   PL+
Sbjct: 1    MLRVFILYAENVHTPDTDISDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLD 60

Query: 59   NDSFLQVTLQDMGSQKKERFIGLATVLLKPLLKQPSEVLFVKDLTLLNHSMKPTDCTVTL 118
              S L V ++D  +  + RF+G A V L+ +L  PS +    +  LL+   +PT  ++ L
Sbjct: 61   QGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPS-LSASFNAPLLDTKKQPTGASLVL 119

Query: 119  QVAH---------------------MSNQDI-EKTGAEDHL---GITAREA--------- 144
            QV++                     + + D+   TG E+     G+T  EA         
Sbjct: 120  QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGG 179

Query: 145  -----ASQKLM------VPG-------STAHRALSSKPQHFQVRVKVFEARQLMGNNIKP 186
                   +KL        PG        T+ + LS KPQ FQ+RV+V E RQL G NIKP
Sbjct: 180  PGAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKP 239

Query: 187  VVKVSIAGQQHQTRIKMGNNPFFNEIFFQNFHEVPAKFFDETILI--------------- 231
            VVKV+ AGQ  +TRI  GN+P FNE  F N  + P + FDE I I               
Sbjct: 240  VVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLG 299

Query: 232  --QTDIGFIYHSPGHTLLRKWLGLCQPNNPGSGVTGYLKVTIYALGVGDQALIDQK-LLY 288
              + D+G IY  P H  LRKWL L  P++  +G  GYLK ++  LG GD+A +++K    
Sbjct: 300  EFRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSE 359

Query: 289  GTDDTDIQIFKSAVVPINMAYLQLFIYCAEDL-----------------HLKKHQSVNPQ 331
              +D +  + +   V +  A+  L ++ AEDL                    K   V+P 
Sbjct: 360  DKEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPF 419

Query: 332  LEVELIGEKLRTHMQTQTDNPIWNQILTFRIQLPCLSSYIKFRVLDCRKKDCPDEIGTAS 391
            +EV   G+ L + +  +T NP WNQ +T     P +   ++ R++D  +    D + T  
Sbjct: 420  VEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTY 479

Query: 392  LSLNQISSTGEEIEGKQS--LEPTSYTPRV-YSGFLPCFGPSFLTLHGGKKAPFRIQEEG 448
            LS+++IS+ G EIE + +  ++P+  +    Y GFLP FGP ++ L+G  +      +  
Sbjct: 480  LSMSKISAPGGEIEEEPAGAVKPSKASDLDDYLGFLPTFGPCYINLYGSPREFTGFPDPY 539

Query: 449  ACIPDSVRDGLAYRGRVFLELITQIKSYQDSTIKDL-SHEVTRIEKHQNRQKYGLCVIFL 507
              +     +G+AYRGR+ L L T++  + +  ++DL + ++ R+EK+  R+KY L   F 
Sbjct: 540  TELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFY 599

Query: 508  SCTMMPNFKELIHFEVSIGHYGNKMDLNYKPLVSSTPYSPVIYDGNIYHYVPWYNTKPVV 567
            S TM+ +  + I FEVSIG+YGNK D+   PL S+T YS  ++DG  Y+Y+PW N KPVV
Sbjct: 600  SATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVV 659

Query: 568  AVTSNWEDVSFRMNCLNLLHFTRDRLKANLD----TLKSTRNPKDPALLYQWEKLLRELA 623
             ++S WED+S R+   N L    DRL+A L+     LK+  + +D   L    +L  EL 
Sbjct: 660  VLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVA--QLTDELI 717

Query: 624  EDCKRPLPCMTYQPKATSLDRKRWQLRSLLLQE-----LAQKAKQAKPKDMVATAEDWLY 678
              C +PL  +   P AT LD+  +QLR+  L +     LA K   ++    +  AEDWL 
Sbjct: 718  AGCSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWLL 777

Query: 679  RLNTVLPEPQMGLPDVMIWLVAKEQRVAYAQVPAHSVLFSPAGALHSGRLCGKIQTLFLQ 738
            RL  +  EPQ  LPD++IW++  ++RVAY +VPAH VLFS  GA + G+ CGK+QT+FL+
Sbjct: 778  RLRALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLK 837

Query: 739  YPEGEGQKDVLPAHLRVCMWLGNVTDSKDLQLLRQGDTAVYAEMYENQAKYK--DQWGQQ 796
            YP  +     +P  +RV +W G   D K+     +G  +V+AE YEN+ K      WG  
Sbjct: 838  YPMEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTT 897

Query: 797  GLYHCPNFSDVMGNKTLPMTDFQPPLGWHWQDSWTVEPQRRLLLDIDINKSQVLEEVYEN 856
            GL + P FSDV G   LP   F+P  GW W   W V P++ LL D+D      +EEV+EN
Sbjct: 898  GLTY-PKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFEN 956

Query: 857  QGRDTRGAWGPAAIPNTDVNGQPMEARENVKCPQGWHFK-KDWVVELNHAVDS--WEYGV 913
            Q R   G W   +   TDVNG+ +  +++++CP GW ++ ++W  +LN AVD   WEY +
Sbjct: 957  QTRLPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSI 1016

Query: 914  GIPPSGLPQVWSPVEKTYHSCRRRRWARVRFRNHGELS----HEQETLSFLQLGLAKGEE 969
             IPP   P+ W P EK Y++ RRRRW R+R R+  ++     H Q          A+ E 
Sbjct: 1017 TIPPERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQ----------AEAEG 1066

Query: 970  EGWEYDT-FGSKFHLNPQPQSRFRRRCWRRRLAPNKDKGIAPIFLLEGSLACEGGSVREE 1028
            EGWEY + FG KFHL  +    FRRR WRRR+ P +  G A +F LEG+L    G V ++
Sbjct: 1067 EGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGAL----GGVMDD 1122

Query: 1029 GDWAWARGNRSSTQEPQGRLSWVQAMDLKYHAGKEEDS---KTWPWGLDRQFRDPQRQDT 1085
                                             K EDS    T  +G++R          
Sbjct: 1123 ---------------------------------KSEDSMSVSTLSFGVNR---------- 1139

Query: 1086 RPPNLPFIYCTFNKPHYYQLFCYIYQARNLVSNQILTFQGPFIRVVFLNHSQCTQTLRSS 1145
                 P I C F+  + Y L CY+YQAR+L +    +F  P+  V FL+ SQ T  ++++
Sbjct: 1140 -----PTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNT 1194

Query: 1146 AGPTWAQTLIFQHLLLYENPQDTKESPPLVVLELWQRDFWGKESLWGRSVWPPMVWLDLQ 1205
              PTW QTLIF  + ++  P    E PP +V+EL+  D +G +   GR +  P +     
Sbjct: 1195 LNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSL----- 1249

Query: 1206 DRILPPMRWHPLVKELGKEEGEILASCELILQTEKLGEKQLPILSV-------------- 1251
               +P + W PL +   +  GE+LAS ELI Q EK     +P   V              
Sbjct: 1250 -ERMPRLAWFPLTRG-SQPSGELLASFELI-QREKPAIHHIPGFEVQETSRILDESEDTD 1306

Query: 1252 -PW-----KNGAYTLPKSIQPTIKRMAIEILAWGLRNMKK-----ASSPQLLVEFGEESL 1300
             P+     +   Y +P++I+P ++R AIEILAWGLRNMK       SSP L+VE G +++
Sbjct: 1307 LPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTV 1366

Query: 1301 RTEPIRDFQTNPNFPESESVLVLTVLMPTEEAYALPLVVKVVDNWAFGQQTVTGQANIDF 1360
            ++  IR+ + NPNF      L + V++P EE Y  P+ VKV+DN  FG++ V GQ  I  
Sbjct: 1367 QSCVIRNLRKNPNF--DICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRS 1424

Query: 1361 LQPYFCDPWAQDYMHPK---------------LPTLSEKKH------QDFLGYLYRKFWF 1399
            L+ + CDP++ +   P+               L  + +K+        D L  L      
Sbjct: 1425 LESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQLADGLSSLAPTNTA 1484

Query: 1400 K--SSKAEDEYEHEVDWWSKLFWATDEHKSL-KYKYKDYHTLKVYECELEAVPAFQGLQD 1456
               SS  E+E+   +DWWSK F +  E +    Y  KD+ TLKVY+ +LE V AF+GL D
Sbjct: 1485 SPPSSPHEEEF---IDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSD 1541

Query: 1457 FCQTFKLYQ---EQPKLDSPVVGEFKGLFRIYPFPENPEAPKPPLQFLVWPEREDFPQPC 1513
            FC TFKLY+   ++   D  V+GEFKGLF+IYP PE+P  P PP QF     +   PQ C
Sbjct: 1542 FCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQG--PQEC 1599

Query: 1514 LVRVYMVRAINLQPQDYNGLCDPYVILKLGKTELGNRDMYQPNTLDPIFGMMFELTCNIP 1573
            LVR+Y+VRA  LQP+D NG CDPY+ + +GK  + ++D Y P TL+P+FG MFELTC +P
Sbjct: 1600 LVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLP 1659

Query: 1574 LEKDLEIQLYDFDLFSPDDKIGTTVIDLENRLLSGFGAHCGLSKSYCQSGPFRWRDQMPP 1633
            LEKDL+I LYD+DL S D+KIG TV+DLENRLLS FGA CGL ++YC SGP +WRDQ+ P
Sbjct: 1660 LEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRP 1719

Query: 1634 SYLLERYAKRKGLPPPLFSPEEDAVFYNGKKFKLQSFEP-KTPTVHGLGPKKERLALYLL 1692
            S LL  + ++  +  P++    D V +  K++ ++  E  + P  H LGP +ERLAL++L
Sbjct: 1720 SQLLHLFCQQHRVKAPVY--RTDRVMFQDKEYSIEEIEAGRIPNPH-LGPVEERLALHVL 1776

Query: 1693 HTQGLVPEHVETRTLYSHSQPGIDQGKVQMWVDIFPKKLGPPGPQVNINPRKPKRKASEH 1752
              QGLVPEHVE+R LYS  QP I+QGK+QMWVD+FPK LG PGP  NI PR+ +      
Sbjct: 1777 QQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRAR------ 1830

Query: 1753 SGHRYELRCIIWKTANVDLVDDNLSREKTSDIYIKGWLYGLEKDMQKTDIHYHSLTGEAD 1812
               R+ LRCIIW T +V L D +L+ EK SDIY+KGW+ G E+  QKTD+HY SL GE +
Sbjct: 1831 ---RFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGN 1887

Query: 1813 FNWRFIFTMDYLAAERTCVQSQKDYIWSLDATSMKFPARLIIQVWDNDIFSPDDFLGVLE 1872
            FNWRFIF  DYL AE+ C  ++KD  W LD T  K PAR++ Q+WDND FS DDFLG L+
Sbjct: 1888 FNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQ 1947

Query: 1873 LDLSDMPLPARHAKQCSIRMMD--ADPKWPYFIQYKHFSLFKKKTVTGWWPCQVLDGGKW 1930
            LDL+ MP PA+ AK+CS+  +D    P+W         SLF++KTV GWWPC   +G K 
Sbjct: 1948 LDLNRMPKPAKTAKKCSLDQLDDAFHPEW-------FVSLFEQKTVKGWWPCVAEEGEKK 2000

Query: 1931 RLSGKVKMSLEILSEKEALIKPAGRGQSEPNQYPTLHPPLRTNTSFTWLRSPVQNFCYIF 1990
             L+GK++M+LEI++E E   +PAG+G+ EPN  P L  P R +TSF W  SP +   +I 
Sbjct: 2001 ILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFIL 2060

Query: 1991 WKRYRFKLIAFMVISIIALMLFNFIYSAPHYLAMSWIKP 2029
            W+R+R+ +I F+++ I+ L L  FIY+ P+Y AM  +KP
Sbjct: 2061 WRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKP 2099


>gi|195976756 dysferlin isoform 10 [Homo sapiens]
          Length = 2087

 Score = 1432 bits (3708), Expect = 0.0
 Identities = 860/2196 (39%), Positives = 1216/2196 (55%), Gaps = 278/2196 (12%)

Query: 1    MLRLVVQSAK-IDPPLAPLPRPCMSIDFRDIKKRTRVVEGN-DPVWNETLIWHLWNRPLE 58
            MLR+ +  A+ +  P   +     S  F  +KKRT+V++ + +PVWNE   W L   PL+
Sbjct: 1    MLRVFILYAENVHTPDTDISDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLD 60

Query: 59   NDSFLQVTLQDMGSQKKERFIGLATVLLKPLLKQPSEVLFVKDLTLLNHSMKPTDCTVTL 118
              S L V ++D  +  + RF+G A V L+ +L  PS +    +  LL+   +PT  ++ L
Sbjct: 61   QGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPS-LSASFNAPLLDTKKQPTGASLVL 119

Query: 119  QVAH---------------------MSNQDI-EKTGAEDHL---GITAREA--------- 144
            QV++                     + + D+   TG E+     G+T  EA         
Sbjct: 120  QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGG 179

Query: 145  -----ASQKLM------VPG-------STAHRALSSKPQHFQVRVKVFEARQLMGNNIKP 186
                   +KL        PG        T+ + LS KPQ FQ+RV+V E RQL G NIKP
Sbjct: 180  PGAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKP 239

Query: 187  VVKVSIAGQQHQTRIKMGNNPFFNEIFFQNFHEVPAKFFDETILI--------------- 231
            VVKV+ AGQ  +TRI  GN+P FNE  F N  + P + FDE I I               
Sbjct: 240  VVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLG 299

Query: 232  --QTDIGFIYHSPGHTLLRKWLGLCQPNNPGSGVTGYLKVTIYALGVGDQALIDQK-LLY 288
              + D+G IY  P H  LRKWL L  P++  +G  GYLK ++  LG GD+A +++K    
Sbjct: 300  EFRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSE 359

Query: 289  GTDDTDIQIFKSAVVPINMAYLQLFIYCAEDL-----------------HLKKHQSVNPQ 331
              +D +  + +   V +  A+  L ++ AEDL                    K   V+P 
Sbjct: 360  DKEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPF 419

Query: 332  LEVELIGEKLRTHMQTQTDNPIWNQILTFRIQLPCLSSYIKFRVLDCRKKDCPDEIGTAS 391
            +EV   G+ L + +  +T NP WNQ +T     P +   ++ R++D  +    D + T  
Sbjct: 420  VEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTY 479

Query: 392  LSLNQISSTGEEIEGKQSLEPTSYTPRVYSGFLPCFGPSFLTLHGGKKAPFRIQEEGACI 451
            LS+++IS+ G EIE              Y GFLP FGP ++ L+G  +      +    +
Sbjct: 480  LSMSKISAPGGEIEVDD-----------YLGFLPTFGPCYINLYGSPREFTGFPDPYTEL 528

Query: 452  PDSVRDGLAYRGRVFLELITQIKSYQDSTIKDL-SHEVTRIEKHQNRQKYGLCVIFLSCT 510
                 +G+AYRGR+ L L T++  + +  ++DL + ++ R+EK+  R+KY L   F S T
Sbjct: 529  NTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFYSAT 588

Query: 511  MMPNFKELIHFEVSIGHYGNKMDLNYKPLVSSTPYSPVIYDGNIYHYVPWYNTKPVVAVT 570
            M+ +  + I FEVSIG+YGNK D+   PL S+T YS  ++DG  Y+Y+PW N KPVV ++
Sbjct: 589  MLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLS 648

Query: 571  SNWEDVSFRMNCLNLLHFTRDRLKANLD----TLKSTRNPKDPALLYQWEKLLRELAEDC 626
            S WED+S R+   N L    DRL+A L+     LK+  + +D   L    +L  EL   C
Sbjct: 649  SYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVA--QLTDELIAGC 706

Query: 627  KRPLPCMTYQPKATSLDRKRWQLRSLLLQE-----LAQKAKQAKPKDMVATAEDWLYRLN 681
             +PL  +   P AT LD+  +QLR+  L +     LA K   ++    +  AEDWL RL 
Sbjct: 707  SQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWLLRLR 766

Query: 682  TVLPEPQMGLPDVMIWLVAKEQRVAYAQVPAHSVLFSPAGALHSGRLCGKIQTLFLQYPE 741
             +  EPQ  LPD++IW++  ++RVAY +VPAH VLFS  GA + G+ CGK+QT+FL+YP 
Sbjct: 767  ALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYPM 826

Query: 742  GEGQKDVLPAHLRVCMWLGNVTDSKDLQLLRQGDTAVYAEMYENQAKYK--DQWGQQGLY 799
             +     +P  +RV +W G   D K+     +G  +V+AE YEN+ K      WG  GL 
Sbjct: 827  EKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTTGLT 886

Query: 800  HCPNFSDVMGNKTLPMTDFQPPLGWHWQDSWTVEPQRRLLLDIDINKSQVLEEVYENQGR 859
            + P FSDV G   LP   F+P  GW W   W V P++ LL D+D      +EEV+ENQ R
Sbjct: 887  Y-PKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTR 945

Query: 860  DTRGAWGPAAIPNTDVNGQPMEARENVKCPQGWHFK-KDWVVELNHAVDS--WEYGVGIP 916
               G W   +   TDVNG+ +  +++++CP GW ++ ++W  +LN AVD   WEY + IP
Sbjct: 946  LPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIP 1005

Query: 917  PSGLPQVWSPVEKTYHSCRRRRWARVRFRNHGELS----HEQETLSFLQLGLAKGEEEGW 972
            P   P+ W P EK Y++ RRRRW R+R R+  ++     H Q          A+ E EGW
Sbjct: 1006 PERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQ----------AEAEGEGW 1055

Query: 973  EYDT-FGSKFHLNPQPQSRFRRRCWRRRLAPNKDKGIAPIFLLEGSLACEGGSVREEGDW 1031
            EY + FG KFHL  +    FRRR WRRR+ P +  G A +F LEG+L    G V ++   
Sbjct: 1056 EYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGAL----GGVMDD--- 1108

Query: 1032 AWARGNRSSTQEPQGRLSWVQAMDLKYHAGKEEDS---KTWPWGLDRQFRDPQRQDTRPP 1088
                                          K EDS    T  +G++R             
Sbjct: 1109 ------------------------------KSEDSMSVSTLSFGVNR------------- 1125

Query: 1089 NLPFIYCTFNKPHYYQLFCYIYQARNLVSNQILTFQGPFIRVVFLNHSQCTQTLRSSAGP 1148
              P I C F+  + Y L CY+YQAR+L +    +F  P+  V FL+ SQ T  ++++  P
Sbjct: 1126 --PTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNP 1183

Query: 1149 TWAQTLIFQHLLLYENPQDTKESPPLVVLELWQRDFWGKESLWGRSVWPPMVWLDLQDRI 1208
            TW QTLIF  + ++  P    E PP +V+EL+  D +G +   GR +  P +        
Sbjct: 1184 TWDQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSL------ER 1237

Query: 1209 LPPMRWHPLVKELGKEEGEILASCELILQTEKLGEKQLPILSV---------------PW 1253
            +P + W PL +   +  GE+LAS ELI Q EK     +P   V               P+
Sbjct: 1238 MPRLAWFPLTRG-SQPSGELLASFELI-QREKPAIHHIPGFEVQETSRILDESEDTDLPY 1295

Query: 1254 -----KNGAYTLPKSIQPTIKRMAIEILAWGLRNMKK-----ASSPQLLVEFGEESLRTE 1303
                 +   Y +P++I+P ++R AIEILAWGLRNMK       SSP L+VE G +++++ 
Sbjct: 1296 PPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTVQSC 1355

Query: 1304 PIRDFQTNPNFPESESVLVLTVLMPTEEAYALPLVVKVVDNWAFGQQTVTGQANIDFLQP 1363
             IR+ + NPNF      L + V++P EE Y  P+ VKV+DN  FG++ V GQ  I  L+ 
Sbjct: 1356 VIRNLRKNPNF--DICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLES 1413

Query: 1364 YFCDPWAQDYMHPK---------------LPTLSEKKH------QDFLGYLYRKFWFK-- 1400
            + CDP++ +   P+               L  + +K+        D L  L         
Sbjct: 1414 FLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQLADGLSSLAPTNTASPP 1473

Query: 1401 SSKAEDEYEHEVDWWSKLFWATDEHKSL-KYKYKDYHTLKVYECELEAVPAFQGLQDFCQ 1459
            SS  E+E+   +DWWSK F +  E +    Y  KD+ TLKVY+ +LE V AF+GL DFC 
Sbjct: 1474 SSPHEEEF---IDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCN 1530

Query: 1460 TFKLYQ---EQPKLDSPVVGEFKGLFRIYPFPENPEAPKPPLQFLVWPEREDFPQPCLVR 1516
            TFKLY+   ++   D  V+GEFKGLF+IYP PE+P  P PP QF     +   PQ CLVR
Sbjct: 1531 TFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQG--PQECLVR 1588

Query: 1517 VYMVRAINLQPQDYNGLCDPYVILKLGKTELGNRDMYQPNTLDPIFGMMFELTCNIPLEK 1576
            +Y+VRA  LQP+D NG CDPY+ + +GK  + ++D Y P TL+P+FG MFELTC +PLEK
Sbjct: 1589 IYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEK 1648

Query: 1577 DLEIQLYDFDLFSPDDKIGTTVIDLENRLLSGFGAHCGLSKSYCQSGPFRWRDQMPPSYL 1636
            DL+I LYD+DL S D+KIG TV+DLENRLLS FGA CGL ++YC SGP +WRDQ+ PS L
Sbjct: 1649 DLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQL 1708

Query: 1637 LERYAKRKGLPPPLFSPEEDAVFYNGKKFKLQSFEP-KTPTVHGLGPKKERLALYLLHTQ 1695
            L  + ++  +  P++    D V +  K++ ++  E  + P  H LGP +ERLAL++L  Q
Sbjct: 1709 LHLFCQQHRVKAPVY--RTDRVMFQDKEYSIEEIEAGRIPNPH-LGPVEERLALHVLQQQ 1765

Query: 1696 GLVPEHVETRTLYSHSQPGIDQGKVQMWVDIFPKKLGPPGPQVNINPRKPKRKASEHSGH 1755
            GLVPEHVE+R LYS  QP I+QGK+QMWVD+FPK LG PGP  NI PR+ +         
Sbjct: 1766 GLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRAR--------- 1816

Query: 1756 RYELRCIIWKTANVDLVDDNLSREKTSDIYIKGWLYGLEKDMQKTDIHYHSLTGEADFNW 1815
            R+ LRCIIW T +V L D +L+ EK SDIY+KGW+ G E+  QKTD+HY SL GE +FNW
Sbjct: 1817 RFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNW 1876

Query: 1816 RFIFTMDYLAAERTCVQSQKDYIWSLDATSMKFPARLIIQVWDNDIFSPDDFLGVLELDL 1875
            RFIF  DYL AE+ C  ++KD  W LD T  K PAR++ Q+WDND FS DDFLG L+LDL
Sbjct: 1877 RFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDL 1936

Query: 1876 SDMPLPARHAKQCSIRMMD--ADPKWPYFIQYKHFSLFKKKTVTGWWPCQVLDGGKWRLS 1933
            + MP PA+ AK+CS+  +D    P+W         SLF++KTV GWWPC   +G K  L+
Sbjct: 1937 NRMPKPAKTAKKCSLDQLDDAFHPEW-------FVSLFEQKTVKGWWPCVAEEGEKKILA 1989

Query: 1934 GKVKMSLEILSEKEALIKPAGRGQSEPNQYPTLHPPLRTNTSFTWLRSPVQNFCYIFWKR 1993
            GK++M+LEI++E E   +PAG+G+ EPN  P L  P R +TSF W  SP +   +I W+R
Sbjct: 1990 GKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRR 2049

Query: 1994 YRFKLIAFMVISIIALMLFNFIYSAPHYLAMSWIKP 2029
            +R+ +I F+++ I+ L L  FIY+ P+Y AM  +KP
Sbjct: 2050 FRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKP 2085


>gi|195976766 dysferlin isoform 7 [Homo sapiens]
          Length = 2112

 Score = 1401 bits (3627), Expect = 0.0
 Identities = 805/1973 (40%), Positives = 1133/1973 (57%), Gaps = 200/1973 (10%)

Query: 155  TAHRALSSKPQHFQVRVKVFEARQLMGNNIKPVVKVSIAGQQHQTRIKMGNNPFFNEIFF 214
            T+ + LS KPQ FQ+RV+V E RQL G NIKPVVKV+ AGQ  +TRI  GN+P FNE  F
Sbjct: 240  TSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLF 299

Query: 215  QNFHEVPAKFFDETILI-----------------QTDIGFIYHSPGHTLLRKWLGLCQPN 257
             N  + P + FDE I I                 + D+G IY  P H  LRKWL L  P+
Sbjct: 300  FNLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPD 359

Query: 258  NPGSGVTGYLKVTIYALGVGDQALIDQK-LLYGTDDTDIQIFKSAVVPINMAYLQLFIYC 316
            +  +G  GYLK ++  LG GD+A +++K      +D +  + +   V +  A+  L ++ 
Sbjct: 360  DFSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFR 419

Query: 317  AEDL-----------------HLKKHQSVNPQLEVELIGEKLRTHMQTQTDNPIWNQILT 359
            AEDL                    K   V+P +EV   G+ L + +  +T NP WNQ +T
Sbjct: 420  AEDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNIT 479

Query: 360  FRIQLPCLSSYIKFRVLDCRKKDCPDEIGTASLSLNQISSTGEEIEGKQS--LEPTSYTP 417
                 P +   ++ R++D  +    D + T  LS+++IS+ G EIE + +  ++P+  + 
Sbjct: 480  LPAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEEEPAGAVKPSKASD 539

Query: 418  RV-YSGFLPCFGPSFLTLHGGKKAPFRIQEEGACIPDSVRDGLAYRGRVFLELITQIKSY 476
               Y GFLP FGP ++ L+G  +      +    +     +G+AYRGR+ L L T++  +
Sbjct: 540  LDDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEH 599

Query: 477  QDSTIKDL-SHEVTRIEKHQNRQKYGLCVIFLSCTMMPNFKELIHFEVSIGHYGNKMDLN 535
             +  ++DL + ++ R+EK+  R+KY L   F S TM+ +  + I FEVSIG+YGNK D+ 
Sbjct: 600  SEQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMT 659

Query: 536  YKPLVSSTPYSPVIYDGNIYHYVPWYNTKPVVAVTSNWEDVSFRMNCLNLLHFTRDRLKA 595
              PL S+T YS  ++DG  Y+Y+PW N KPVV ++S WED+S R+   N L    DRL+A
Sbjct: 660  CLPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEA 719

Query: 596  NLD----TLKSTRNPKDPALLYQWEKLLRELAEDCKRPLPCMTYQPKATSLDRKRWQLRS 651
             L+     LK+  + +D   L    +L  EL   C +PL  +   P AT LD+  +QLR+
Sbjct: 720  GLEQVHLALKAQCSTEDVDSLVA--QLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRT 777

Query: 652  LLLQE-----LAQKAKQAKPKDMVATAEDWLYRLNTVLPEPQMGLPDVMIWLVAKEQRVA 706
              L +     LA K   ++    +  AEDWL RL  +  EPQ  LPD++IW++  ++RVA
Sbjct: 778  HHLSQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVA 837

Query: 707  YAQVPAHSVLFSPAGALHSGRLCGKIQTLFLQYPEGEGQKDVLPAHLRVCMWLGNVTDSK 766
            Y +VPAH VLFS  GA + G+ CGK+QT+FL+YP  +     +P  +RV +W G   D K
Sbjct: 838  YQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEK 897

Query: 767  DLQLLRQGDTAVYAEMYENQAKYK--DQWGQQGLYHCPNFSDVMGNKTLPMTDFQPPLGW 824
            +     +G  +V+AE YEN+ K      WG  GL + P FSDV G   LP   F+P  GW
Sbjct: 898  EFNQFAEGKLSVFAETYENETKLALVGNWGTTGLTY-PKFSDVTGKIKLPKDSFRPSAGW 956

Query: 825  HWQDSWTVEPQRRLLLDIDINKSQVLEEVYENQGRDTRGAWGPAAIPNTDVNGQPMEARE 884
             W   W V P++ LL D+D      +EEV+ENQ R   G W   +   TDVNG+ +  ++
Sbjct: 957  TWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKD 1016

Query: 885  NVKCPQGWHFK-KDWVVELNHAVDS--WEYGVGIPPSGLPQVWSPVEKTYHSCRRRRWAR 941
            +++CP GW ++ ++W  +LN AVD   WEY + IPP   P+ W P EK Y++ RRRRW R
Sbjct: 1017 DIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVR 1076

Query: 942  VRFRNHGELS----HEQETLSFLQLGLAKGEEEGWEYDT-FGSKFHLNPQPQSRFRRRCW 996
            +R R+  ++     H Q          A+ E EGWEY + FG KFHL  +    FRRR W
Sbjct: 1077 LRRRDLSQMEALKRHRQ----------AEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRW 1126

Query: 997  RRRLAPNKDKGIAPIFLLEGSLACEGGSVREEGDWAWARGNRSSTQEPQGRLSWVQAMDL 1056
            RRR+ P +  G A +F LEG+L    G V ++                            
Sbjct: 1127 RRRMEPLEKTGPAAVFALEGAL----GGVMDD---------------------------- 1154

Query: 1057 KYHAGKEEDS---KTWPWGLDRQFRDPQRQDTRPPNLPFIYCTFNKPHYYQLFCYIYQAR 1113
                 K EDS    T  +G++R               P I C F+  + Y L CY+YQAR
Sbjct: 1155 -----KSEDSMSVSTLSFGVNR---------------PTISCIFDYGNRYHLRCYMYQAR 1194

Query: 1114 NLVSNQILTFQGPFIRVVFLNHSQCTQTLRSSAGPTWAQTLIFQHLLLYENPQDTKESPP 1173
            +L +    +F  P+  V FL+ SQ T  ++++  PTW QTLIF  + ++  P    E PP
Sbjct: 1195 DLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPP 1254

Query: 1174 LVVLELWQRDFWGKESLWGRSVWPPMVWLDLQDRILPPMRWHPLVKELGKEEGEILASCE 1233
             +V+EL+  D +G +   GR +  P +        +P + W PL +   +  GE+LAS E
Sbjct: 1255 SIVVELYDHDTYGADEFMGRCICQPSL------ERMPRLAWFPLTRG-SQPSGELLASFE 1307

Query: 1234 LILQTEKLGEKQLPILSV---------------PW-----KNGAYTLPKSIQPTIKRMAI 1273
            LI Q EK     +P   V               P+     +   Y +P++I+P ++R AI
Sbjct: 1308 LI-QREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAI 1366

Query: 1274 EILAWGLRNMKK-----ASSPQLLVEFGEESLRTEPIRDFQTNPNFPESESVLVLTVLMP 1328
            EILAWGLRNMK       SSP L+VE G +++++  IR+ + NPNF      L + V++P
Sbjct: 1367 EILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPNF--DICTLFMEVMLP 1424

Query: 1329 TEEAYALPLVVKVVDNWAFGQQTVTGQANIDFLQPYFCDPWAQDYMHPK-----LPTLSE 1383
             EE Y  P+ VKV+DN  FG++ V GQ  I  L+ + CDP++ +   P+     +  LS 
Sbjct: 1425 REELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSP 1484

Query: 1384 KKHQDFLGYLYRKFWFKSSKAEDEYEHEVDWWSKLFWATDEHKSL-KYKYKDYHTLKVYE 1442
               +D L  +  K          + E  +DWWSK F +  E +    Y  KD+ TLKVY+
Sbjct: 1485 G--EDVLIDIDDK----EPLIPIQEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYD 1538

Query: 1443 CELEAVPAFQGLQDFCQTFKLYQ---EQPKLDSPVVGEFKGLFRIYPFPENPEAPKPPLQ 1499
             +LE V AF+GL DFC TFKLY+   ++   D  V+GEFKGLF+IYP PE+P  P PP Q
Sbjct: 1539 TQLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQ 1598

Query: 1500 FLVWPEREDFPQPCLVRVYMVRAINLQPQDYNGLCDPYVILKLGKTELGNRDMYQPNTLD 1559
            F     +   PQ CLVR+Y+VRA  LQP+D NG CDPY+ + +GK  + ++D Y P TL+
Sbjct: 1599 FHQLAAQG--PQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLE 1656

Query: 1560 PIFGMMFELTCNIPLEKDLEIQLYDFDLFSPDDKIGTTVIDLENRLLSGFGAHCGLSKSY 1619
            P+FG MFELTC +PLEKDL+I LYD+DL S D+KIG TV+DLENRLLS FGA CGL ++Y
Sbjct: 1657 PVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTY 1716

Query: 1620 CQSGPFRWRDQMPPSYLLERYAKRKGLPPPLFSPEEDAVFYNGKKFKLQSFEP-KTPTVH 1678
            C SGP +WRDQ+ PS LL  + ++  +  P++    D V +  K++ ++  E  + P  H
Sbjct: 1717 CVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVY--RTDRVMFQDKEYSIEEIEAGRIPNPH 1774

Query: 1679 GLGPKKERLALYLLHTQGLVPEHVETRTLYSHSQPGIDQGKVQMWVDIFPKKLGPPGPQV 1738
             LGP +ERLAL++L  QGLVPEHVE+R LYS  QP I+QGK+QMWVD+FPK LG PGP  
Sbjct: 1775 -LGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPF 1833

Query: 1739 NINPRKPKRKASEHSGHRYELRCIIWKTANVDLVDDNLSREKTSDIYIKGWLYGLEKDMQ 1798
            NI PR+ +         R+ LRCIIW T +V L D +L+ EK SDIY+KGW+ G E+  Q
Sbjct: 1834 NITPRRAR---------RFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQ 1884

Query: 1799 KTDIHYHSLTGEADFNWRFIFTMDYLAAERTCVQSQKDYIWSLDATSMKFPARLIIQVWD 1858
            KTD+HY SL GE +FNWRFIF  DYL AE+ C  ++KD  W LD T  K PAR++ Q+WD
Sbjct: 1885 KTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWD 1944

Query: 1859 NDIFSPDDFLGVLELDLSDMPLPARHAKQCSIRMMD--ADPKWPYFIQYKHFSLFKKKTV 1916
            ND FS DDFLG L+LDL+ MP PA+ AK+CS+  +D    P+W         SLF++KTV
Sbjct: 1945 NDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEW-------FVSLFEQKTV 1997

Query: 1917 TGWWPCQVLDGGKWRLSGKVKMSLEILSEKEALIKPAGRGQSEPNQYPTLHPPLRTNTSF 1976
             GWWPC   +G K  L+GK++M+LEI++E E   +PAG+G+ EPN  P L  P R +TSF
Sbjct: 1998 KGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSF 2057

Query: 1977 TWLRSPVQNFCYIFWKRYRFKLIAFMVISIIALMLFNFIYSAPHYLAMSWIKP 2029
             W  SP +   +I W+R+R+ +I F+++ I+ L L  FIY+ P+Y AM  +KP
Sbjct: 2058 LWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKP 2110



 Score = 65.9 bits (159), Expect = 4e-10
 Identities = 38/103 (36%), Positives = 61/103 (59%), Gaps = 2/103 (1%)

Query: 21  PCMSIDFRDIKKRTRVVEGN-DPVWNETLIWHLWNRPLENDSFLQVTLQDMGSQKKERFI 79
           P  S+ FR +KKRT+V++ + +PVWNE   W L   PL+  S L V ++D  +  + RF+
Sbjct: 23  PVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLDQGSELHVVVKDHETMGRNRFL 82

Query: 80  GLATVLLKPLLKQPSEVLFVKDLTLLNHSMKPTDCTVTLQVAH 122
           G A V L+ +L  PS +    +  LL+   +PT  ++ LQV++
Sbjct: 83  GEAKVPLREVLATPS-LSASFNAPLLDTKKQPTGASLVLQVSY 124



 Score = 40.0 bits (92), Expect = 0.024
 Identities = 24/86 (27%), Positives = 46/86 (53%), Gaps = 1/86 (1%)

Query: 20  RPCMSIDFRDIKKRTRVVEGNDPVWNETLIWHLWNRPLE-NDSFLQVTLQDMGSQKKERF 78
           +P + +      KRTR+ +GN P++NETL ++L++ P E  D  + +T+ D  S + +  
Sbjct: 270 KPVVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDAL 329

Query: 79  IGLATVLLKPLLKQPSEVLFVKDLTL 104
           +G   + +  + ++P      K L L
Sbjct: 330 LGEFRMDVGTIYREPRHAYLRKWLLL 355


>gi|195976760 dysferlin isoform 12 [Homo sapiens]
          Length = 2111

 Score = 1401 bits (3627), Expect = 0.0
 Identities = 805/1973 (40%), Positives = 1133/1973 (57%), Gaps = 200/1973 (10%)

Query: 155  TAHRALSSKPQHFQVRVKVFEARQLMGNNIKPVVKVSIAGQQHQTRIKMGNNPFFNEIFF 214
            T+ + LS KPQ FQ+RV+V E RQL G NIKPVVKV+ AGQ  +TRI  GN+P FNE  F
Sbjct: 239  TSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLF 298

Query: 215  QNFHEVPAKFFDETILI-----------------QTDIGFIYHSPGHTLLRKWLGLCQPN 257
             N  + P + FDE I I                 + D+G IY  P H  LRKWL L  P+
Sbjct: 299  FNLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPD 358

Query: 258  NPGSGVTGYLKVTIYALGVGDQALIDQK-LLYGTDDTDIQIFKSAVVPINMAYLQLFIYC 316
            +  +G  GYLK ++  LG GD+A +++K      +D +  + +   V +  A+  L ++ 
Sbjct: 359  DFSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFR 418

Query: 317  AEDL-----------------HLKKHQSVNPQLEVELIGEKLRTHMQTQTDNPIWNQILT 359
            AEDL                    K   V+P +EV   G+ L + +  +T NP WNQ +T
Sbjct: 419  AEDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNIT 478

Query: 360  FRIQLPCLSSYIKFRVLDCRKKDCPDEIGTASLSLNQISSTGEEIEGKQS--LEPTSYTP 417
                 P +   ++ R++D  +    D + T  LS+++IS+ G EIE + +  ++P+  + 
Sbjct: 479  LPAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEEEPAGAVKPSKASD 538

Query: 418  RV-YSGFLPCFGPSFLTLHGGKKAPFRIQEEGACIPDSVRDGLAYRGRVFLELITQIKSY 476
               Y GFLP FGP ++ L+G  +      +    +     +G+AYRGR+ L L T++  +
Sbjct: 539  LDDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEH 598

Query: 477  QDSTIKDL-SHEVTRIEKHQNRQKYGLCVIFLSCTMMPNFKELIHFEVSIGHYGNKMDLN 535
             +  ++DL + ++ R+EK+  R+KY L   F S TM+ +  + I FEVSIG+YGNK D+ 
Sbjct: 599  SEQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMT 658

Query: 536  YKPLVSSTPYSPVIYDGNIYHYVPWYNTKPVVAVTSNWEDVSFRMNCLNLLHFTRDRLKA 595
              PL S+T YS  ++DG  Y+Y+PW N KPVV ++S WED+S R+   N L    DRL+A
Sbjct: 659  CLPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEA 718

Query: 596  NLD----TLKSTRNPKDPALLYQWEKLLRELAEDCKRPLPCMTYQPKATSLDRKRWQLRS 651
             L+     LK+  + +D   L    +L  EL   C +PL  +   P AT LD+  +QLR+
Sbjct: 719  GLEQVHLALKAQCSTEDVDSLVA--QLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRT 776

Query: 652  LLLQE-----LAQKAKQAKPKDMVATAEDWLYRLNTVLPEPQMGLPDVMIWLVAKEQRVA 706
              L +     LA K   ++    +  AEDWL RL  +  EPQ  LPD++IW++  ++RVA
Sbjct: 777  HHLSQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVA 836

Query: 707  YAQVPAHSVLFSPAGALHSGRLCGKIQTLFLQYPEGEGQKDVLPAHLRVCMWLGNVTDSK 766
            Y +VPAH VLFS  GA + G+ CGK+QT+FL+YP  +     +P  +RV +W G   D K
Sbjct: 837  YQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEK 896

Query: 767  DLQLLRQGDTAVYAEMYENQAKYK--DQWGQQGLYHCPNFSDVMGNKTLPMTDFQPPLGW 824
            +     +G  +V+AE YEN+ K      WG  GL + P FSDV G   LP   F+P  GW
Sbjct: 897  EFNQFAEGKLSVFAETYENETKLALVGNWGTTGLTY-PKFSDVTGKIKLPKDSFRPSAGW 955

Query: 825  HWQDSWTVEPQRRLLLDIDINKSQVLEEVYENQGRDTRGAWGPAAIPNTDVNGQPMEARE 884
             W   W V P++ LL D+D      +EEV+ENQ R   G W   +   TDVNG+ +  ++
Sbjct: 956  TWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKD 1015

Query: 885  NVKCPQGWHFK-KDWVVELNHAVDS--WEYGVGIPPSGLPQVWSPVEKTYHSCRRRRWAR 941
            +++CP GW ++ ++W  +LN AVD   WEY + IPP   P+ W P EK Y++ RRRRW R
Sbjct: 1016 DIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVR 1075

Query: 942  VRFRNHGELS----HEQETLSFLQLGLAKGEEEGWEYDT-FGSKFHLNPQPQSRFRRRCW 996
            +R R+  ++     H Q          A+ E EGWEY + FG KFHL  +    FRRR W
Sbjct: 1076 LRRRDLSQMEALKRHRQ----------AEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRW 1125

Query: 997  RRRLAPNKDKGIAPIFLLEGSLACEGGSVREEGDWAWARGNRSSTQEPQGRLSWVQAMDL 1056
            RRR+ P +  G A +F LEG+L    G V ++                            
Sbjct: 1126 RRRMEPLEKTGPAAVFALEGAL----GGVMDD---------------------------- 1153

Query: 1057 KYHAGKEEDS---KTWPWGLDRQFRDPQRQDTRPPNLPFIYCTFNKPHYYQLFCYIYQAR 1113
                 K EDS    T  +G++R               P I C F+  + Y L CY+YQAR
Sbjct: 1154 -----KSEDSMSVSTLSFGVNR---------------PTISCIFDYGNRYHLRCYMYQAR 1193

Query: 1114 NLVSNQILTFQGPFIRVVFLNHSQCTQTLRSSAGPTWAQTLIFQHLLLYENPQDTKESPP 1173
            +L +    +F  P+  V FL+ SQ T  ++++  PTW QTLIF  + ++  P    E PP
Sbjct: 1194 DLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPP 1253

Query: 1174 LVVLELWQRDFWGKESLWGRSVWPPMVWLDLQDRILPPMRWHPLVKELGKEEGEILASCE 1233
             +V+EL+  D +G +   GR +  P +        +P + W PL +   +  GE+LAS E
Sbjct: 1254 SIVVELYDHDTYGADEFMGRCICQPSL------ERMPRLAWFPLTRG-SQPSGELLASFE 1306

Query: 1234 LILQTEKLGEKQLPILSV---------------PW-----KNGAYTLPKSIQPTIKRMAI 1273
            LI Q EK     +P   V               P+     +   Y +P++I+P ++R AI
Sbjct: 1307 LI-QREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAI 1365

Query: 1274 EILAWGLRNMKK-----ASSPQLLVEFGEESLRTEPIRDFQTNPNFPESESVLVLTVLMP 1328
            EILAWGLRNMK       SSP L+VE G +++++  IR+ + NPNF      L + V++P
Sbjct: 1366 EILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPNF--DICTLFMEVMLP 1423

Query: 1329 TEEAYALPLVVKVVDNWAFGQQTVTGQANIDFLQPYFCDPWAQDYMHPK-----LPTLSE 1383
             EE Y  P+ VKV+DN  FG++ V GQ  I  L+ + CDP++ +   P+     +  LS 
Sbjct: 1424 REELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSP 1483

Query: 1384 KKHQDFLGYLYRKFWFKSSKAEDEYEHEVDWWSKLFWATDEHKSL-KYKYKDYHTLKVYE 1442
               +D L  +  K          + E  +DWWSK F +  E +    Y  KD+ TLKVY+
Sbjct: 1484 G--EDVLIDIDDK----EPLIPIQEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYD 1537

Query: 1443 CELEAVPAFQGLQDFCQTFKLYQ---EQPKLDSPVVGEFKGLFRIYPFPENPEAPKPPLQ 1499
             +LE V AF+GL DFC TFKLY+   ++   D  V+GEFKGLF+IYP PE+P  P PP Q
Sbjct: 1538 TQLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQ 1597

Query: 1500 FLVWPEREDFPQPCLVRVYMVRAINLQPQDYNGLCDPYVILKLGKTELGNRDMYQPNTLD 1559
            F     +   PQ CLVR+Y+VRA  LQP+D NG CDPY+ + +GK  + ++D Y P TL+
Sbjct: 1598 FHQLAAQG--PQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLE 1655

Query: 1560 PIFGMMFELTCNIPLEKDLEIQLYDFDLFSPDDKIGTTVIDLENRLLSGFGAHCGLSKSY 1619
            P+FG MFELTC +PLEKDL+I LYD+DL S D+KIG TV+DLENRLLS FGA CGL ++Y
Sbjct: 1656 PVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTY 1715

Query: 1620 CQSGPFRWRDQMPPSYLLERYAKRKGLPPPLFSPEEDAVFYNGKKFKLQSFEP-KTPTVH 1678
            C SGP +WRDQ+ PS LL  + ++  +  P++    D V +  K++ ++  E  + P  H
Sbjct: 1716 CVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVY--RTDRVMFQDKEYSIEEIEAGRIPNPH 1773

Query: 1679 GLGPKKERLALYLLHTQGLVPEHVETRTLYSHSQPGIDQGKVQMWVDIFPKKLGPPGPQV 1738
             LGP +ERLAL++L  QGLVPEHVE+R LYS  QP I+QGK+QMWVD+FPK LG PGP  
Sbjct: 1774 -LGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPF 1832

Query: 1739 NINPRKPKRKASEHSGHRYELRCIIWKTANVDLVDDNLSREKTSDIYIKGWLYGLEKDMQ 1798
            NI PR+ +         R+ LRCIIW T +V L D +L+ EK SDIY+KGW+ G E+  Q
Sbjct: 1833 NITPRRAR---------RFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQ 1883

Query: 1799 KTDIHYHSLTGEADFNWRFIFTMDYLAAERTCVQSQKDYIWSLDATSMKFPARLIIQVWD 1858
            KTD+HY SL GE +FNWRFIF  DYL AE+ C  ++KD  W LD T  K PAR++ Q+WD
Sbjct: 1884 KTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWD 1943

Query: 1859 NDIFSPDDFLGVLELDLSDMPLPARHAKQCSIRMMD--ADPKWPYFIQYKHFSLFKKKTV 1916
            ND FS DDFLG L+LDL+ MP PA+ AK+CS+  +D    P+W         SLF++KTV
Sbjct: 1944 NDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEW-------FVSLFEQKTV 1996

Query: 1917 TGWWPCQVLDGGKWRLSGKVKMSLEILSEKEALIKPAGRGQSEPNQYPTLHPPLRTNTSF 1976
             GWWPC   +G K  L+GK++M+LEI++E E   +PAG+G+ EPN  P L  P R +TSF
Sbjct: 1997 KGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSF 2056

Query: 1977 TWLRSPVQNFCYIFWKRYRFKLIAFMVISIIALMLFNFIYSAPHYLAMSWIKP 2029
             W  SP +   +I W+R+R+ +I F+++ I+ L L  FIY+ P+Y AM  +KP
Sbjct: 2057 LWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKP 2109



 Score = 61.2 bits (147), Expect = 1e-08
 Identities = 41/124 (33%), Positives = 68/124 (54%), Gaps = 3/124 (2%)

Query: 1   MLRLVVQSAK-IDPPLAPLPRPCMSIDFRDIKKRTRVVEGN-DPVWNETLIWHLWNRPLE 58
           MLR+ +  A+ +  P   +     S  F  +KKRT+V++ + +PVWNE   W L   PL+
Sbjct: 1   MLRVFILYAENVHTPDTDISDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLD 60

Query: 59  NDSFLQVTLQDMGSQKKERFIGLATVLLKPLLKQPSEVLFVKDLTLLNHSMKPTDCTVTL 118
             S L V ++D  +  + RF+G A V L+ +L  PS +    +  LL+   +PT  ++ L
Sbjct: 61  QGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPS-LSASFNAPLLDTKKQPTGASLVL 119

Query: 119 QVAH 122
           QV++
Sbjct: 120 QVSY 123



 Score = 40.0 bits (92), Expect = 0.024
 Identities = 24/86 (27%), Positives = 46/86 (53%), Gaps = 1/86 (1%)

Query: 20  RPCMSIDFRDIKKRTRVVEGNDPVWNETLIWHLWNRPLE-NDSFLQVTLQDMGSQKKERF 78
           +P + +      KRTR+ +GN P++NETL ++L++ P E  D  + +T+ D  S + +  
Sbjct: 269 KPVVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDAL 328

Query: 79  IGLATVLLKPLLKQPSEVLFVKDLTL 104
           +G   + +  + ++P      K L L
Sbjct: 329 LGEFRMDVGTIYREPRHAYLRKWLLL 354


>gi|195976775 dysferlin isoform 4 [Homo sapiens]
          Length = 2098

 Score = 1400 bits (3624), Expect = 0.0
 Identities = 804/1970 (40%), Positives = 1126/1970 (57%), Gaps = 208/1970 (10%)

Query: 155  TAHRALSSKPQHFQVRVKVFEARQLMGNNIKPVVKVSIAGQQHQTRIKMGNNPFFNEIFF 214
            T+ + LS KPQ FQ+RV+V E RQL G NIKPVVKV+ AGQ  +TRI  GN+P FNE  F
Sbjct: 240  TSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLF 299

Query: 215  QNFHEVPAKFFDETILI-----------------QTDIGFIYHSPGHTLLRKWLGLCQPN 257
             N  + P + FDE I I                 + D+G IY  P H  LRKWL L  P+
Sbjct: 300  FNLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPD 359

Query: 258  NPGSGVTGYLKVTIYALGVGDQALIDQK-LLYGTDDTDIQIFKSAVVPINMAYLQLFIYC 316
            +  +G  GYLK ++  LG GD+A +++K      +D +  + +   V +  A+  L ++ 
Sbjct: 360  DFSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFR 419

Query: 317  AEDL-----------------HLKKHQSVNPQLEVELIGEKLRTHMQTQTDNPIWNQILT 359
            AEDL                    K   V+P +EV   G+ L + +  +T NP WNQ +T
Sbjct: 420  AEDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNIT 479

Query: 360  FRIQLPCLSSYIKFRVLDCRKKDCPDEIGTASLSLNQISSTGEEIEGKQSLEPTSYTPRV 419
                 P +   ++ R++D  +    D + T  LS+++IS+ G EIE              
Sbjct: 480  LPAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEVDD----------- 528

Query: 420  YSGFLPCFGPSFLTLHGGKKAPFRIQEEGACIPDSVRDGLAYRGRVFLELITQIKSYQDS 479
            Y GFLP FGP ++ L+G  +      +    +     +G+AYRGR+ L L T++  + + 
Sbjct: 529  YLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSEQ 588

Query: 480  TIKDL-SHEVTRIEKHQNRQKYGLCVIFLSCTMMPNFKELIHFEVSIGHYGNKMDLNYKP 538
             ++DL + ++ R+EK+  R+KY L   F S TM+ +  + I FEVSIG+YGNK D+   P
Sbjct: 589  KVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTCLP 648

Query: 539  LVSSTPYSPVIYDGNIYHYVPWYNTKPVVAVTSNWEDVSFRMNCLNLLHFTRDRLKANLD 598
            L S+T YS  ++DG  Y+Y+PW N KPVV ++S WED+S R+   N L    DRL+A L+
Sbjct: 649  LASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAGLE 708

Query: 599  ----TLKSTRNPKDPALLYQWEKLLRELAEDCKRPLPCMTYQPKATSLDRKRWQLRSLLL 654
                 LK+  + +D   L    +L  EL   C +PL  +   P AT LD+  +QLR+  L
Sbjct: 709  QVHLALKAQCSTEDVDSLVA--QLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL 766

Query: 655  QE-----LAQKAKQAKPKDMVATAEDWLYRLNTVLPEPQMGLPDVMIWLVAKEQRVAYAQ 709
             +     LA K   ++    +  AEDWL RL  +  EPQ  LPD++IW++  ++RVAY +
Sbjct: 767  SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR 826

Query: 710  VPAHSVLFSPAGALHSGRLCGKIQTLFLQYPEGEGQKDVLPAHLRVCMWLGNVTDSKDLQ 769
            VPAH VLFS  GA + G+ CGK+QT+FL+YP  +     +P  +RV +W G   D K+  
Sbjct: 827  VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN 886

Query: 770  LLRQGDTAVYAEMYENQAKYK--DQWGQQGLYHCPNFSDVMGNKTLPMTDFQPPLGWHWQ 827
               +G  +V+AE YEN+ K      WG  GL + P FSDV G   LP   F+P  GW W 
Sbjct: 887  QFAEGKLSVFAETYENETKLALVGNWGTTGLTY-PKFSDVTGKIKLPKDSFRPSAGWTWA 945

Query: 828  DSWTVEPQRRLLLDIDINKSQVLEEVYENQGRDTRGAWGPAAIPNTDVNGQPMEARENVK 887
              W V P++ LL D+D      +EEV+ENQ R   G W   +   TDVNG+ +  +++++
Sbjct: 946  GDWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIE 1005

Query: 888  CPQGWHFK-KDWVVELNHAVDS--WEYGVGIPPSGLPQVWSPVEKTYHSCRRRRWARVRF 944
            CP GW ++ ++W  +LN AVD   WEY + IPP   P+ W P EK Y++ RRRRW R+R 
Sbjct: 1006 CPLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRR 1065

Query: 945  RNHGELS----HEQETLSFLQLGLAKGEEEGWEYDT-FGSKFHLNPQPQSRFRRRCWRRR 999
            R+  ++     H Q          A+ E EGWEY + FG KFHL  +    FRRR WRRR
Sbjct: 1066 RDLSQMEALKRHRQ----------AEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRR 1115

Query: 1000 LAPNKDKGIAPIFLLEGSLACEGGSVREEGDWAWARGNRSSTQEPQGRLSWVQAMDLKYH 1059
            + P +  G A +F LEG+L    G V ++                               
Sbjct: 1116 MEPLEKTGPAAVFALEGAL----GGVMDD------------------------------- 1140

Query: 1060 AGKEEDS---KTWPWGLDRQFRDPQRQDTRPPNLPFIYCTFNKPHYYQLFCYIYQARNLV 1116
              K EDS    T  +G++R               P I C F+  + Y L CY+YQAR+L 
Sbjct: 1141 --KSEDSMSVSTLSFGVNR---------------PTISCIFDYGNRYHLRCYMYQARDLA 1183

Query: 1117 SNQILTFQGPFIRVVFLNHSQCTQTLRSSAGPTWAQTLIFQHLLLYENPQDTKESPPLVV 1176
            +    +F  P+  V FL+ SQ T  ++++  PTW QTLIF  + ++  P    E PP +V
Sbjct: 1184 AMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIV 1243

Query: 1177 LELWQRDFWGKESLWGRSVWPPMVWLDLQDRILPPMRWHPLVKELGKEEGEILASCELIL 1236
            +EL+  D +G +   GR +  P +        +P + W PL +   +  GE+LAS ELI 
Sbjct: 1244 VELYDHDTYGADEFMGRCICQPSL------ERMPRLAWFPLTRG-SQPSGELLASFELI- 1295

Query: 1237 QTEKLGEKQLPILSV---------------PW-----KNGAYTLPKSIQPTIKRMAIEIL 1276
            Q EK     +P   V               P+     +   Y +P++I+P ++R AIEIL
Sbjct: 1296 QREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEIL 1355

Query: 1277 AWGLRNMKK-----ASSPQLLVEFGEESLRTEPIRDFQTNPNFPESESVLVLTVLMPTEE 1331
            AWGLRNMK       SSP L+VE G +++++  IR+ + NPNF      L + V++P EE
Sbjct: 1356 AWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPNF--DICTLFMEVMLPREE 1413

Query: 1332 AYALPLVVKVVDNWAFGQQTVTGQANIDFLQPYFCDPWAQDYMHPK-----LPTLSEKKH 1386
             Y  P+ VKV+DN  FG++ V GQ  I  L+ + CDP++ +   P+     +  LS    
Sbjct: 1414 LYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPG-- 1471

Query: 1387 QDFLGYLYRKFWFKSSKAEDEYEHEVDWWSKLFWATDEHKSL-KYKYKDYHTLKVYECEL 1445
            +D L  +  K          + E  +DWWSK F +  E +    Y  KD+ TLKVY+ +L
Sbjct: 1472 EDVLIDIDDK----EPLIPIQEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQL 1527

Query: 1446 EAVPAFQGLQDFCQTFKLYQ---EQPKLDSPVVGEFKGLFRIYPFPENPEAPKPPLQFLV 1502
            E V AF+GL DFC TFKLY+   ++   D  V+GEFKGLF+IYP PE+P  P PP QF  
Sbjct: 1528 ENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQ 1587

Query: 1503 WPEREDFPQPCLVRVYMVRAINLQPQDYNGLCDPYVILKLGKTELGNRDMYQPNTLDPIF 1562
               +   PQ CLVR+Y+VRA  LQP+D NG CDPY+ + +GK  + ++D Y P TL+P+F
Sbjct: 1588 LAAQG--PQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVF 1645

Query: 1563 GMMFELTCNIPLEKDLEIQLYDFDLFSPDDKIGTTVIDLENRLLSGFGAHCGLSKSYCQS 1622
            G MFELTC +PLEKDL+I LYD+DL S D+KIG TV+DLENRLLS FGA CGL ++YC S
Sbjct: 1646 GKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVS 1705

Query: 1623 GPFRWRDQMPPSYLLERYAKRKGLPPPLFSPEEDAVFYNGKKFKLQSFEP-KTPTVHGLG 1681
            GP +WRDQ+ PS LL  + ++  +  P++    D V +  K++ ++  E  + P  H LG
Sbjct: 1706 GPNQWRDQLRPSQLLHLFCQQHRVKAPVY--RTDRVMFQDKEYSIEEIEAGRIPNPH-LG 1762

Query: 1682 PKKERLALYLLHTQGLVPEHVETRTLYSHSQPGIDQGKVQMWVDIFPKKLGPPGPQVNIN 1741
            P +ERLAL++L  QGLVPEHVE+R LYS  QP I+QGK+QMWVD+FPK LG PGP  NI 
Sbjct: 1763 PVEERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNIT 1822

Query: 1742 PRKPKRKASEHSGHRYELRCIIWKTANVDLVDDNLSREKTSDIYIKGWLYGLEKDMQKTD 1801
            PR+ +         R+ LRCIIW T +V L D +L+ EK SDIY+KGW+ G E+  QKTD
Sbjct: 1823 PRRAR---------RFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTD 1873

Query: 1802 IHYHSLTGEADFNWRFIFTMDYLAAERTCVQSQKDYIWSLDATSMKFPARLIIQVWDNDI 1861
            +HY SL GE +FNWRFIF  DYL AE+ C  ++KD  W LD T  K PAR++ Q+WDND 
Sbjct: 1874 VHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDK 1933

Query: 1862 FSPDDFLGVLELDLSDMPLPARHAKQCSIRMMD--ADPKWPYFIQYKHFSLFKKKTVTGW 1919
            FS DDFLG L+LDL+ MP PA+ AK+CS+  +D    P+W         SLF++KTV GW
Sbjct: 1934 FSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEW-------FVSLFEQKTVKGW 1986

Query: 1920 WPCQVLDGGKWRLSGKVKMSLEILSEKEALIKPAGRGQSEPNQYPTLHPPLRTNTSFTWL 1979
            WPC   +G K  L+GK++M+LEI++E E   +PAG+G+ EPN  P L  P R +TSF W 
Sbjct: 1987 WPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWF 2046

Query: 1980 RSPVQNFCYIFWKRYRFKLIAFMVISIIALMLFNFIYSAPHYLAMSWIKP 2029
             SP +   +I W+R+R+ +I F+++ I+ L L  FIY+ P+Y AM  +KP
Sbjct: 2047 TSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKP 2096



 Score = 65.9 bits (159), Expect = 4e-10
 Identities = 38/103 (36%), Positives = 61/103 (59%), Gaps = 2/103 (1%)

Query: 21  PCMSIDFRDIKKRTRVVEGN-DPVWNETLIWHLWNRPLENDSFLQVTLQDMGSQKKERFI 79
           P  S+ FR +KKRT+V++ + +PVWNE   W L   PL+  S L V ++D  +  + RF+
Sbjct: 23  PVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLDQGSELHVVVKDHETMGRNRFL 82

Query: 80  GLATVLLKPLLKQPSEVLFVKDLTLLNHSMKPTDCTVTLQVAH 122
           G A V L+ +L  PS +    +  LL+   +PT  ++ LQV++
Sbjct: 83  GEAKVPLREVLATPS-LSASFNAPLLDTKKQPTGASLVLQVSY 124



 Score = 40.0 bits (92), Expect = 0.024
 Identities = 24/86 (27%), Positives = 46/86 (53%), Gaps = 1/86 (1%)

Query: 20  RPCMSIDFRDIKKRTRVVEGNDPVWNETLIWHLWNRPLE-NDSFLQVTLQDMGSQKKERF 78
           +P + +      KRTR+ +GN P++NETL ++L++ P E  D  + +T+ D  S + +  
Sbjct: 270 KPVVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDAL 329

Query: 79  IGLATVLLKPLLKQPSEVLFVKDLTL 104
           +G   + +  + ++P      K L L
Sbjct: 330 LGEFRMDVGTIYREPRHAYLRKWLLL 355


>gi|195976762 dysferlin isoform 13 [Homo sapiens]
          Length = 2097

 Score = 1400 bits (3624), Expect = 0.0
 Identities = 804/1970 (40%), Positives = 1126/1970 (57%), Gaps = 208/1970 (10%)

Query: 155  TAHRALSSKPQHFQVRVKVFEARQLMGNNIKPVVKVSIAGQQHQTRIKMGNNPFFNEIFF 214
            T+ + LS KPQ FQ+RV+V E RQL G NIKPVVKV+ AGQ  +TRI  GN+P FNE  F
Sbjct: 239  TSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLF 298

Query: 215  QNFHEVPAKFFDETILI-----------------QTDIGFIYHSPGHTLLRKWLGLCQPN 257
             N  + P + FDE I I                 + D+G IY  P H  LRKWL L  P+
Sbjct: 299  FNLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPD 358

Query: 258  NPGSGVTGYLKVTIYALGVGDQALIDQK-LLYGTDDTDIQIFKSAVVPINMAYLQLFIYC 316
            +  +G  GYLK ++  LG GD+A +++K      +D +  + +   V +  A+  L ++ 
Sbjct: 359  DFSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFR 418

Query: 317  AEDL-----------------HLKKHQSVNPQLEVELIGEKLRTHMQTQTDNPIWNQILT 359
            AEDL                    K   V+P +EV   G+ L + +  +T NP WNQ +T
Sbjct: 419  AEDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNIT 478

Query: 360  FRIQLPCLSSYIKFRVLDCRKKDCPDEIGTASLSLNQISSTGEEIEGKQSLEPTSYTPRV 419
                 P +   ++ R++D  +    D + T  LS+++IS+ G EIE              
Sbjct: 479  LPAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEVDD----------- 527

Query: 420  YSGFLPCFGPSFLTLHGGKKAPFRIQEEGACIPDSVRDGLAYRGRVFLELITQIKSYQDS 479
            Y GFLP FGP ++ L+G  +      +    +     +G+AYRGR+ L L T++  + + 
Sbjct: 528  YLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSEQ 587

Query: 480  TIKDL-SHEVTRIEKHQNRQKYGLCVIFLSCTMMPNFKELIHFEVSIGHYGNKMDLNYKP 538
             ++DL + ++ R+EK+  R+KY L   F S TM+ +  + I FEVSIG+YGNK D+   P
Sbjct: 588  KVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTCLP 647

Query: 539  LVSSTPYSPVIYDGNIYHYVPWYNTKPVVAVTSNWEDVSFRMNCLNLLHFTRDRLKANLD 598
            L S+T YS  ++DG  Y+Y+PW N KPVV ++S WED+S R+   N L    DRL+A L+
Sbjct: 648  LASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAGLE 707

Query: 599  ----TLKSTRNPKDPALLYQWEKLLRELAEDCKRPLPCMTYQPKATSLDRKRWQLRSLLL 654
                 LK+  + +D   L    +L  EL   C +PL  +   P AT LD+  +QLR+  L
Sbjct: 708  QVHLALKAQCSTEDVDSLVA--QLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL 765

Query: 655  QE-----LAQKAKQAKPKDMVATAEDWLYRLNTVLPEPQMGLPDVMIWLVAKEQRVAYAQ 709
             +     LA K   ++    +  AEDWL RL  +  EPQ  LPD++IW++  ++RVAY +
Sbjct: 766  SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR 825

Query: 710  VPAHSVLFSPAGALHSGRLCGKIQTLFLQYPEGEGQKDVLPAHLRVCMWLGNVTDSKDLQ 769
            VPAH VLFS  GA + G+ CGK+QT+FL+YP  +     +P  +RV +W G   D K+  
Sbjct: 826  VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN 885

Query: 770  LLRQGDTAVYAEMYENQAKYK--DQWGQQGLYHCPNFSDVMGNKTLPMTDFQPPLGWHWQ 827
               +G  +V+AE YEN+ K      WG  GL + P FSDV G   LP   F+P  GW W 
Sbjct: 886  QFAEGKLSVFAETYENETKLALVGNWGTTGLTY-PKFSDVTGKIKLPKDSFRPSAGWTWA 944

Query: 828  DSWTVEPQRRLLLDIDINKSQVLEEVYENQGRDTRGAWGPAAIPNTDVNGQPMEARENVK 887
              W V P++ LL D+D      +EEV+ENQ R   G W   +   TDVNG+ +  +++++
Sbjct: 945  GDWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIE 1004

Query: 888  CPQGWHFK-KDWVVELNHAVDS--WEYGVGIPPSGLPQVWSPVEKTYHSCRRRRWARVRF 944
            CP GW ++ ++W  +LN AVD   WEY + IPP   P+ W P EK Y++ RRRRW R+R 
Sbjct: 1005 CPLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRR 1064

Query: 945  RNHGELS----HEQETLSFLQLGLAKGEEEGWEYDT-FGSKFHLNPQPQSRFRRRCWRRR 999
            R+  ++     H Q          A+ E EGWEY + FG KFHL  +    FRRR WRRR
Sbjct: 1065 RDLSQMEALKRHRQ----------AEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRR 1114

Query: 1000 LAPNKDKGIAPIFLLEGSLACEGGSVREEGDWAWARGNRSSTQEPQGRLSWVQAMDLKYH 1059
            + P +  G A +F LEG+L    G V ++                               
Sbjct: 1115 MEPLEKTGPAAVFALEGAL----GGVMDD------------------------------- 1139

Query: 1060 AGKEEDS---KTWPWGLDRQFRDPQRQDTRPPNLPFIYCTFNKPHYYQLFCYIYQARNLV 1116
              K EDS    T  +G++R               P I C F+  + Y L CY+YQAR+L 
Sbjct: 1140 --KSEDSMSVSTLSFGVNR---------------PTISCIFDYGNRYHLRCYMYQARDLA 1182

Query: 1117 SNQILTFQGPFIRVVFLNHSQCTQTLRSSAGPTWAQTLIFQHLLLYENPQDTKESPPLVV 1176
            +    +F  P+  V FL+ SQ T  ++++  PTW QTLIF  + ++  P    E PP +V
Sbjct: 1183 AMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIV 1242

Query: 1177 LELWQRDFWGKESLWGRSVWPPMVWLDLQDRILPPMRWHPLVKELGKEEGEILASCELIL 1236
            +EL+  D +G +   GR +  P +        +P + W PL +   +  GE+LAS ELI 
Sbjct: 1243 VELYDHDTYGADEFMGRCICQPSL------ERMPRLAWFPLTRG-SQPSGELLASFELI- 1294

Query: 1237 QTEKLGEKQLPILSV---------------PW-----KNGAYTLPKSIQPTIKRMAIEIL 1276
            Q EK     +P   V               P+     +   Y +P++I+P ++R AIEIL
Sbjct: 1295 QREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEIL 1354

Query: 1277 AWGLRNMKK-----ASSPQLLVEFGEESLRTEPIRDFQTNPNFPESESVLVLTVLMPTEE 1331
            AWGLRNMK       SSP L+VE G +++++  IR+ + NPNF      L + V++P EE
Sbjct: 1355 AWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPNF--DICTLFMEVMLPREE 1412

Query: 1332 AYALPLVVKVVDNWAFGQQTVTGQANIDFLQPYFCDPWAQDYMHPK-----LPTLSEKKH 1386
             Y  P+ VKV+DN  FG++ V GQ  I  L+ + CDP++ +   P+     +  LS    
Sbjct: 1413 LYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPG-- 1470

Query: 1387 QDFLGYLYRKFWFKSSKAEDEYEHEVDWWSKLFWATDEHKSL-KYKYKDYHTLKVYECEL 1445
            +D L  +  K          + E  +DWWSK F +  E +    Y  KD+ TLKVY+ +L
Sbjct: 1471 EDVLIDIDDK----EPLIPIQEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQL 1526

Query: 1446 EAVPAFQGLQDFCQTFKLYQ---EQPKLDSPVVGEFKGLFRIYPFPENPEAPKPPLQFLV 1502
            E V AF+GL DFC TFKLY+   ++   D  V+GEFKGLF+IYP PE+P  P PP QF  
Sbjct: 1527 ENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQ 1586

Query: 1503 WPEREDFPQPCLVRVYMVRAINLQPQDYNGLCDPYVILKLGKTELGNRDMYQPNTLDPIF 1562
               +   PQ CLVR+Y+VRA  LQP+D NG CDPY+ + +GK  + ++D Y P TL+P+F
Sbjct: 1587 LAAQG--PQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVF 1644

Query: 1563 GMMFELTCNIPLEKDLEIQLYDFDLFSPDDKIGTTVIDLENRLLSGFGAHCGLSKSYCQS 1622
            G MFELTC +PLEKDL+I LYD+DL S D+KIG TV+DLENRLLS FGA CGL ++YC S
Sbjct: 1645 GKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVS 1704

Query: 1623 GPFRWRDQMPPSYLLERYAKRKGLPPPLFSPEEDAVFYNGKKFKLQSFEP-KTPTVHGLG 1681
            GP +WRDQ+ PS LL  + ++  +  P++    D V +  K++ ++  E  + P  H LG
Sbjct: 1705 GPNQWRDQLRPSQLLHLFCQQHRVKAPVY--RTDRVMFQDKEYSIEEIEAGRIPNPH-LG 1761

Query: 1682 PKKERLALYLLHTQGLVPEHVETRTLYSHSQPGIDQGKVQMWVDIFPKKLGPPGPQVNIN 1741
            P +ERLAL++L  QGLVPEHVE+R LYS  QP I+QGK+QMWVD+FPK LG PGP  NI 
Sbjct: 1762 PVEERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNIT 1821

Query: 1742 PRKPKRKASEHSGHRYELRCIIWKTANVDLVDDNLSREKTSDIYIKGWLYGLEKDMQKTD 1801
            PR+ +         R+ LRCIIW T +V L D +L+ EK SDIY+KGW+ G E+  QKTD
Sbjct: 1822 PRRAR---------RFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTD 1872

Query: 1802 IHYHSLTGEADFNWRFIFTMDYLAAERTCVQSQKDYIWSLDATSMKFPARLIIQVWDNDI 1861
            +HY SL GE +FNWRFIF  DYL AE+ C  ++KD  W LD T  K PAR++ Q+WDND 
Sbjct: 1873 VHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDK 1932

Query: 1862 FSPDDFLGVLELDLSDMPLPARHAKQCSIRMMD--ADPKWPYFIQYKHFSLFKKKTVTGW 1919
            FS DDFLG L+LDL+ MP PA+ AK+CS+  +D    P+W         SLF++KTV GW
Sbjct: 1933 FSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEW-------FVSLFEQKTVKGW 1985

Query: 1920 WPCQVLDGGKWRLSGKVKMSLEILSEKEALIKPAGRGQSEPNQYPTLHPPLRTNTSFTWL 1979
            WPC   +G K  L+GK++M+LEI++E E   +PAG+G+ EPN  P L  P R +TSF W 
Sbjct: 1986 WPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWF 2045

Query: 1980 RSPVQNFCYIFWKRYRFKLIAFMVISIIALMLFNFIYSAPHYLAMSWIKP 2029
             SP +   +I W+R+R+ +I F+++ I+ L L  FIY+ P+Y AM  +KP
Sbjct: 2046 TSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKP 2095



 Score = 61.2 bits (147), Expect = 1e-08
 Identities = 41/124 (33%), Positives = 68/124 (54%), Gaps = 3/124 (2%)

Query: 1   MLRLVVQSAK-IDPPLAPLPRPCMSIDFRDIKKRTRVVEGN-DPVWNETLIWHLWNRPLE 58
           MLR+ +  A+ +  P   +     S  F  +KKRT+V++ + +PVWNE   W L   PL+
Sbjct: 1   MLRVFILYAENVHTPDTDISDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLD 60

Query: 59  NDSFLQVTLQDMGSQKKERFIGLATVLLKPLLKQPSEVLFVKDLTLLNHSMKPTDCTVTL 118
             S L V ++D  +  + RF+G A V L+ +L  PS +    +  LL+   +PT  ++ L
Sbjct: 61  QGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPS-LSASFNAPLLDTKKQPTGASLVL 119

Query: 119 QVAH 122
           QV++
Sbjct: 120 QVSY 123



 Score = 40.0 bits (92), Expect = 0.024
 Identities = 24/86 (27%), Positives = 46/86 (53%), Gaps = 1/86 (1%)

Query: 20  RPCMSIDFRDIKKRTRVVEGNDPVWNETLIWHLWNRPLE-NDSFLQVTLQDMGSQKKERF 78
           +P + +      KRTR+ +GN P++NETL ++L++ P E  D  + +T+ D  S + +  
Sbjct: 269 KPVVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDAL 328

Query: 79  IGLATVLLKPLLKQPSEVLFVKDLTL 104
           +G   + +  + ++P      K L L
Sbjct: 329 LGEFRMDVGTIYREPRHAYLRKWLLL 354


>gi|195976779 dysferlin isoform 1 [Homo sapiens]
          Length = 2119

 Score = 1398 bits (3618), Expect = 0.0
 Identities = 807/1988 (40%), Positives = 1130/1988 (56%), Gaps = 223/1988 (11%)

Query: 155  TAHRALSSKPQHFQVRVKVFEARQLMGNNIKPVVKVSIAGQQHQTRIKMGNNPFFNEIFF 214
            T+ + LS KPQ FQ+RV+V E RQL G NIKPVVKV+ AGQ  +TRI  GN+P FNE  F
Sbjct: 240  TSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLF 299

Query: 215  QNFHEVPAKFFDETILI-----------------QTDIGFIYHSPGHTLLRKWLGLCQPN 257
             N  + P + FDE I I                 + D+G IY  P H  LRKWL L  P+
Sbjct: 300  FNLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPD 359

Query: 258  NPGSGVTGYLKVTIYALGVGDQALIDQK-LLYGTDDTDIQIFKSAVVPINMAYLQLFIYC 316
            +  +G  GYLK ++  LG GD+A +++K      +D +  + +   V +  A+  L ++ 
Sbjct: 360  DFSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFR 419

Query: 317  AEDL-----------------HLKKHQSVNPQLEVELIGEKLRTHMQTQTDNPIWNQILT 359
            AEDL                    K   V+P +EV   G+ L + +  +T NP WNQ +T
Sbjct: 420  AEDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNIT 479

Query: 360  FRIQLPCLSSYIKFRVLDCRKKDCPDEIGTASLSLNQISSTGEEIEGKQSLEPTSYTPRV 419
                 P +   ++ R++D  +    D + T  LS+++IS+ G EIE              
Sbjct: 480  LPAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEVDD----------- 528

Query: 420  YSGFLPCFGPSFLTLHGGKKAPFRIQEEGACIPDSVRDGLAYRGRVFLELITQIKSYQDS 479
            Y GFLP FGP ++ L+G  +      +    +     +G+AYRGR+ L L T++  + + 
Sbjct: 529  YLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSEQ 588

Query: 480  TIKDL-SHEVTRIEKHQNRQKYGLCVIFLSCTMMPNFKELIHFEVSIGHYGNKMDLNYKP 538
             ++DL + ++ R+EK+  R+KY L   F S TM+ +  + I FEVSIG+YGNK D+   P
Sbjct: 589  KVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTCLP 648

Query: 539  LVSSTPYSPVIYDGNIYHYVPWYNTKPVVAVTSNWEDVSFRMNCLNLLHFTRDRLKANLD 598
            L S+T YS  ++DG  Y+Y+PW N KPVV ++S WED+S R+   N L    DRL+A L+
Sbjct: 649  LASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAGLE 708

Query: 599  ----TLKSTRNPKDPALLYQWEKLLRELAEDCKRPLPCMTYQPKATSLDRKRWQLRSLLL 654
                 LK+  + +D   L    +L  EL   C +PL  +   P AT LD+  +QLR+  L
Sbjct: 709  QVHLALKAQCSTEDVDSLVA--QLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL 766

Query: 655  QE-----LAQKAKQAKPKDMVATAEDWLYRLNTVLPEPQMGLPDVMIWLVAKEQRVAYAQ 709
             +     LA K   ++    +  AEDWL RL  +  EPQ  LPD++IW++  ++RVAY +
Sbjct: 767  SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR 826

Query: 710  VPAHSVLFSPAGALHSGRLCGKIQTLFLQYPEGEGQKDVLPAHLRVCMWLGNVTDSKDLQ 769
            VPAH VLFS  GA + G+ CGK+QT+FL+YP  +     +P  +RV +W G   D K+  
Sbjct: 827  VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN 886

Query: 770  LLRQGDTAVYAEMYENQAKYK--DQWGQQGLYHCPNFSDVMGNKTLPMTDFQPPLGWHWQ 827
               +G  +V+AE YEN+ K      WG  GL + P FSDV G   LP   F+P  GW W 
Sbjct: 887  QFAEGKLSVFAETYENETKLALVGNWGTTGLTY-PKFSDVTGKIKLPKDSFRPSAGWTWA 945

Query: 828  DSWTVEPQRRLLLDIDINKSQVLEEVYENQGRDTRGAWGPAAIPNTDVNGQPMEARENVK 887
              W V P++ LL D+D      +EEV+ENQ R   G W   +   TDVNG+ +  +++++
Sbjct: 946  GDWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIE 1005

Query: 888  CPQGWHFK-KDWVVELNHAVDS--WEYGVGIPPSGLPQVWSPVEKTYHSCRRRRWARVRF 944
            CP GW ++ ++W  +LN AVD   WEY + IPP   P+ W P EK Y++ RRRRW R+R 
Sbjct: 1006 CPLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRR 1065

Query: 945  RNHGELS----HEQETLSFLQLGLAKGEEEGWEYDT-FGSKFHLNPQPQSRFRRRCWRRR 999
            R+  ++     H Q          A+ E EGWEY + FG KFHL  +    FRRR WRRR
Sbjct: 1066 RDLSQMEALKRHRQ----------AEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRR 1115

Query: 1000 LAPNKDKGIAPIFLLEGSLACEGGSVREEGDWAWARGNRSSTQEPQGRLSWVQAMDLKYH 1059
            + P +  G A +F LEG+L    G V ++                               
Sbjct: 1116 MEPLEKTGPAAVFALEGAL----GGVMDD------------------------------- 1140

Query: 1060 AGKEEDS---KTWPWGLDRQFRDPQRQDTRPPNLPFIYCTFNKPHYYQLFCYIYQARNLV 1116
              K EDS    T  +G++R               P I C F+  + Y L CY+YQAR+L 
Sbjct: 1141 --KSEDSMSVSTLSFGVNR---------------PTISCIFDYGNRYHLRCYMYQARDLA 1183

Query: 1117 SNQILTFQGPFIRVVFLNHSQCTQTLRSSAGPTWAQTLIFQHLLLYENPQDTKESPPLVV 1176
            +    +F  P+  V FL+ SQ T  ++++  PTW QTLIF  + ++  P    E PP +V
Sbjct: 1184 AMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIV 1243

Query: 1177 LELWQRDFWGKESLWGRSVWPPMVWLDLQDRILPPMRWHPLVKELGKEEGEILASCELIL 1236
            +EL+  D +G +   GR +  P +        +P + W PL +   +  GE+LAS ELI 
Sbjct: 1244 VELYDHDTYGADEFMGRCICQPSL------ERMPRLAWFPLTRG-SQPSGELLASFELI- 1295

Query: 1237 QTEKLGEKQLPILSV---------------PW-----KNGAYTLPKSIQPTIKRMAIEIL 1276
            Q EK     +P   V               P+     +   Y +P++I+P ++R AIEIL
Sbjct: 1296 QREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEIL 1355

Query: 1277 AWGLRNMKK-----ASSPQLLVEFGEESLRTEPIRDFQTNPNFPESESVLVLTVLMPTEE 1331
            AWGLRNMK       SSP L+VE G +++++  IR+ + NPNF      L + V++P EE
Sbjct: 1356 AWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPNF--DICTLFMEVMLPREE 1413

Query: 1332 AYALPLVVKVVDNWAFGQQTVTGQANIDFLQPYFCDPWAQDYMHPK-------------- 1377
             Y  P+ VKV+DN  FG++ V GQ  I  L+ + CDP++ +   P+              
Sbjct: 1414 LYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGED 1473

Query: 1378 -LPTLSEKKH------QDFLGYLYRKFWFK--SSKAEDEYEHEVDWWSKLFWATDEHKSL 1428
             L  + +K+        D L  L         SS  E+E+   +DWWSK F +  E +  
Sbjct: 1474 VLIDIDDKEPLIPIQLADGLSSLAPTNTASPPSSPHEEEF---IDWWSKFFASIGEREKC 1530

Query: 1429 -KYKYKDYHTLKVYECELEAVPAFQGLQDFCQTFKLYQ---EQPKLDSPVVGEFKGLFRI 1484
              Y  KD+ TLKVY+ +LE V AF+GL DFC TFKLY+   ++   D  V+GEFKGLF+I
Sbjct: 1531 GSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKI 1590

Query: 1485 YPFPENPEAPKPPLQFLVWPEREDFPQPCLVRVYMVRAINLQPQDYNGLCDPYVILKLGK 1544
            YP PE+P  P PP QF     +   PQ CLVR+Y+VRA  LQP+D NG CDPY+ + +GK
Sbjct: 1591 YPLPEDPAIPMPPRQFHQLAAQG--PQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGK 1648

Query: 1545 TELGNRDMYQPNTLDPIFGMMFELTCNIPLEKDLEIQLYDFDLFSPDDKIGTTVIDLENR 1604
              + ++D Y P TL+P+FG MFELTC +PLEKDL+I LYD+DL S D+KIG TV+DLENR
Sbjct: 1649 KSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENR 1708

Query: 1605 LLSGFGAHCGLSKSYCQSGPFRWRDQMPPSYLLERYAKRKGLPPPLFSPEEDAVFYNGKK 1664
            LLS FGA CGL ++YC SGP +WRDQ+ PS LL  + ++  +  P++    D V +  K+
Sbjct: 1709 LLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVY--RTDRVMFQDKE 1766

Query: 1665 FKLQSFEP-KTPTVHGLGPKKERLALYLLHTQGLVPEHVETRTLYSHSQPGIDQGKVQMW 1723
            + ++  E  + P  H LGP +ERLAL++L  QGLVPEHVE+R LYS  QP I+QGK+QMW
Sbjct: 1767 YSIEEIEAGRIPNPH-LGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMW 1825

Query: 1724 VDIFPKKLGPPGPQVNINPRKPKRKASEHSGHRYELRCIIWKTANVDLVDDNLSREKTSD 1783
            VD+FPK LG PGP  NI PR+ +         R+ LRCIIW T +V L D +L+ EK SD
Sbjct: 1826 VDLFPKALGRPGPPFNITPRRAR---------RFFLRCIIWNTRDVILDDLSLTGEKMSD 1876

Query: 1784 IYIKGWLYGLEKDMQKTDIHYHSLTGEADFNWRFIFTMDYLAAERTCVQSQKDYIWSLDA 1843
            IY+KGW+ G E+  QKTD+HY SL GE +FNWRFIF  DYL AE+ C  ++KD  W LD 
Sbjct: 1877 IYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDK 1936

Query: 1844 TSMKFPARLIIQVWDNDIFSPDDFLGVLELDLSDMPLPARHAKQCSIRMMD--ADPKWPY 1901
            T  K PAR++ Q+WDND FS DDFLG L+LDL+ MP PA+ AK+CS+  +D    P+W  
Sbjct: 1937 TESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEW-- 1994

Query: 1902 FIQYKHFSLFKKKTVTGWWPCQVLDGGKWRLSGKVKMSLEILSEKEALIKPAGRGQSEPN 1961
                   SLF++KTV GWWPC   +G K  L+GK++M+LEI++E E   +PAG+G+ EPN
Sbjct: 1995 -----FVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPN 2049

Query: 1962 QYPTLHPPLRTNTSFTWLRSPVQNFCYIFWKRYRFKLIAFMVISIIALMLFNFIYSAPHY 2021
              P L  P R +TSF W  SP +   +I W+R+R+ +I F+++ I+ L L  FIY+ P+Y
Sbjct: 2050 MNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNY 2109

Query: 2022 LAMSWIKP 2029
             AM  +KP
Sbjct: 2110 AAMKLVKP 2117



 Score = 65.9 bits (159), Expect = 4e-10
 Identities = 38/103 (36%), Positives = 61/103 (59%), Gaps = 2/103 (1%)

Query: 21  PCMSIDFRDIKKRTRVVEGN-DPVWNETLIWHLWNRPLENDSFLQVTLQDMGSQKKERFI 79
           P  S+ FR +KKRT+V++ + +PVWNE   W L   PL+  S L V ++D  +  + RF+
Sbjct: 23  PVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLDQGSELHVVVKDHETMGRNRFL 82

Query: 80  GLATVLLKPLLKQPSEVLFVKDLTLLNHSMKPTDCTVTLQVAH 122
           G A V L+ +L  PS +    +  LL+   +PT  ++ LQV++
Sbjct: 83  GEAKVPLREVLATPS-LSASFNAPLLDTKKQPTGASLVLQVSY 124



 Score = 40.0 bits (92), Expect = 0.024
 Identities = 24/86 (27%), Positives = 46/86 (53%), Gaps = 1/86 (1%)

Query: 20  RPCMSIDFRDIKKRTRVVEGNDPVWNETLIWHLWNRPLE-NDSFLQVTLQDMGSQKKERF 78
           +P + +      KRTR+ +GN P++NETL ++L++ P E  D  + +T+ D  S + +  
Sbjct: 270 KPVVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDAL 329

Query: 79  IGLATVLLKPLLKQPSEVLFVKDLTL 104
           +G   + +  + ++P      K L L
Sbjct: 330 LGEFRMDVGTIYREPRHAYLRKWLLL 355


>gi|195976764 dysferlin isoform 14 [Homo sapiens]
          Length = 2118

 Score = 1398 bits (3618), Expect = 0.0
 Identities = 807/1988 (40%), Positives = 1130/1988 (56%), Gaps = 223/1988 (11%)

Query: 155  TAHRALSSKPQHFQVRVKVFEARQLMGNNIKPVVKVSIAGQQHQTRIKMGNNPFFNEIFF 214
            T+ + LS KPQ FQ+RV+V E RQL G NIKPVVKV+ AGQ  +TRI  GN+P FNE  F
Sbjct: 239  TSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLF 298

Query: 215  QNFHEVPAKFFDETILI-----------------QTDIGFIYHSPGHTLLRKWLGLCQPN 257
             N  + P + FDE I I                 + D+G IY  P H  LRKWL L  P+
Sbjct: 299  FNLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPD 358

Query: 258  NPGSGVTGYLKVTIYALGVGDQALIDQK-LLYGTDDTDIQIFKSAVVPINMAYLQLFIYC 316
            +  +G  GYLK ++  LG GD+A +++K      +D +  + +   V +  A+  L ++ 
Sbjct: 359  DFSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFR 418

Query: 317  AEDL-----------------HLKKHQSVNPQLEVELIGEKLRTHMQTQTDNPIWNQILT 359
            AEDL                    K   V+P +EV   G+ L + +  +T NP WNQ +T
Sbjct: 419  AEDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNIT 478

Query: 360  FRIQLPCLSSYIKFRVLDCRKKDCPDEIGTASLSLNQISSTGEEIEGKQSLEPTSYTPRV 419
                 P +   ++ R++D  +    D + T  LS+++IS+ G EIE              
Sbjct: 479  LPAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEVDD----------- 527

Query: 420  YSGFLPCFGPSFLTLHGGKKAPFRIQEEGACIPDSVRDGLAYRGRVFLELITQIKSYQDS 479
            Y GFLP FGP ++ L+G  +      +    +     +G+AYRGR+ L L T++  + + 
Sbjct: 528  YLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSEQ 587

Query: 480  TIKDL-SHEVTRIEKHQNRQKYGLCVIFLSCTMMPNFKELIHFEVSIGHYGNKMDLNYKP 538
             ++DL + ++ R+EK+  R+KY L   F S TM+ +  + I FEVSIG+YGNK D+   P
Sbjct: 588  KVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTCLP 647

Query: 539  LVSSTPYSPVIYDGNIYHYVPWYNTKPVVAVTSNWEDVSFRMNCLNLLHFTRDRLKANLD 598
            L S+T YS  ++DG  Y+Y+PW N KPVV ++S WED+S R+   N L    DRL+A L+
Sbjct: 648  LASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAGLE 707

Query: 599  ----TLKSTRNPKDPALLYQWEKLLRELAEDCKRPLPCMTYQPKATSLDRKRWQLRSLLL 654
                 LK+  + +D   L    +L  EL   C +PL  +   P AT LD+  +QLR+  L
Sbjct: 708  QVHLALKAQCSTEDVDSLVA--QLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL 765

Query: 655  QE-----LAQKAKQAKPKDMVATAEDWLYRLNTVLPEPQMGLPDVMIWLVAKEQRVAYAQ 709
             +     LA K   ++    +  AEDWL RL  +  EPQ  LPD++IW++  ++RVAY +
Sbjct: 766  SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR 825

Query: 710  VPAHSVLFSPAGALHSGRLCGKIQTLFLQYPEGEGQKDVLPAHLRVCMWLGNVTDSKDLQ 769
            VPAH VLFS  GA + G+ CGK+QT+FL+YP  +     +P  +RV +W G   D K+  
Sbjct: 826  VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN 885

Query: 770  LLRQGDTAVYAEMYENQAKYK--DQWGQQGLYHCPNFSDVMGNKTLPMTDFQPPLGWHWQ 827
               +G  +V+AE YEN+ K      WG  GL + P FSDV G   LP   F+P  GW W 
Sbjct: 886  QFAEGKLSVFAETYENETKLALVGNWGTTGLTY-PKFSDVTGKIKLPKDSFRPSAGWTWA 944

Query: 828  DSWTVEPQRRLLLDIDINKSQVLEEVYENQGRDTRGAWGPAAIPNTDVNGQPMEARENVK 887
              W V P++ LL D+D      +EEV+ENQ R   G W   +   TDVNG+ +  +++++
Sbjct: 945  GDWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIE 1004

Query: 888  CPQGWHFK-KDWVVELNHAVDS--WEYGVGIPPSGLPQVWSPVEKTYHSCRRRRWARVRF 944
            CP GW ++ ++W  +LN AVD   WEY + IPP   P+ W P EK Y++ RRRRW R+R 
Sbjct: 1005 CPLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRR 1064

Query: 945  RNHGELS----HEQETLSFLQLGLAKGEEEGWEYDT-FGSKFHLNPQPQSRFRRRCWRRR 999
            R+  ++     H Q          A+ E EGWEY + FG KFHL  +    FRRR WRRR
Sbjct: 1065 RDLSQMEALKRHRQ----------AEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRR 1114

Query: 1000 LAPNKDKGIAPIFLLEGSLACEGGSVREEGDWAWARGNRSSTQEPQGRLSWVQAMDLKYH 1059
            + P +  G A +F LEG+L    G V ++                               
Sbjct: 1115 MEPLEKTGPAAVFALEGAL----GGVMDD------------------------------- 1139

Query: 1060 AGKEEDS---KTWPWGLDRQFRDPQRQDTRPPNLPFIYCTFNKPHYYQLFCYIYQARNLV 1116
              K EDS    T  +G++R               P I C F+  + Y L CY+YQAR+L 
Sbjct: 1140 --KSEDSMSVSTLSFGVNR---------------PTISCIFDYGNRYHLRCYMYQARDLA 1182

Query: 1117 SNQILTFQGPFIRVVFLNHSQCTQTLRSSAGPTWAQTLIFQHLLLYENPQDTKESPPLVV 1176
            +    +F  P+  V FL+ SQ T  ++++  PTW QTLIF  + ++  P    E PP +V
Sbjct: 1183 AMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIV 1242

Query: 1177 LELWQRDFWGKESLWGRSVWPPMVWLDLQDRILPPMRWHPLVKELGKEEGEILASCELIL 1236
            +EL+  D +G +   GR +  P +        +P + W PL +   +  GE+LAS ELI 
Sbjct: 1243 VELYDHDTYGADEFMGRCICQPSL------ERMPRLAWFPLTRG-SQPSGELLASFELI- 1294

Query: 1237 QTEKLGEKQLPILSV---------------PW-----KNGAYTLPKSIQPTIKRMAIEIL 1276
            Q EK     +P   V               P+     +   Y +P++I+P ++R AIEIL
Sbjct: 1295 QREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEIL 1354

Query: 1277 AWGLRNMKK-----ASSPQLLVEFGEESLRTEPIRDFQTNPNFPESESVLVLTVLMPTEE 1331
            AWGLRNMK       SSP L+VE G +++++  IR+ + NPNF      L + V++P EE
Sbjct: 1355 AWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPNF--DICTLFMEVMLPREE 1412

Query: 1332 AYALPLVVKVVDNWAFGQQTVTGQANIDFLQPYFCDPWAQDYMHPK-------------- 1377
             Y  P+ VKV+DN  FG++ V GQ  I  L+ + CDP++ +   P+              
Sbjct: 1413 LYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGED 1472

Query: 1378 -LPTLSEKKH------QDFLGYLYRKFWFK--SSKAEDEYEHEVDWWSKLFWATDEHKSL 1428
             L  + +K+        D L  L         SS  E+E+   +DWWSK F +  E +  
Sbjct: 1473 VLIDIDDKEPLIPIQLADGLSSLAPTNTASPPSSPHEEEF---IDWWSKFFASIGEREKC 1529

Query: 1429 -KYKYKDYHTLKVYECELEAVPAFQGLQDFCQTFKLYQ---EQPKLDSPVVGEFKGLFRI 1484
              Y  KD+ TLKVY+ +LE V AF+GL DFC TFKLY+   ++   D  V+GEFKGLF+I
Sbjct: 1530 GSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKI 1589

Query: 1485 YPFPENPEAPKPPLQFLVWPEREDFPQPCLVRVYMVRAINLQPQDYNGLCDPYVILKLGK 1544
            YP PE+P  P PP QF     +   PQ CLVR+Y+VRA  LQP+D NG CDPY+ + +GK
Sbjct: 1590 YPLPEDPAIPMPPRQFHQLAAQG--PQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGK 1647

Query: 1545 TELGNRDMYQPNTLDPIFGMMFELTCNIPLEKDLEIQLYDFDLFSPDDKIGTTVIDLENR 1604
              + ++D Y P TL+P+FG MFELTC +PLEKDL+I LYD+DL S D+KIG TV+DLENR
Sbjct: 1648 KSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENR 1707

Query: 1605 LLSGFGAHCGLSKSYCQSGPFRWRDQMPPSYLLERYAKRKGLPPPLFSPEEDAVFYNGKK 1664
            LLS FGA CGL ++YC SGP +WRDQ+ PS LL  + ++  +  P++    D V +  K+
Sbjct: 1708 LLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVY--RTDRVMFQDKE 1765

Query: 1665 FKLQSFEP-KTPTVHGLGPKKERLALYLLHTQGLVPEHVETRTLYSHSQPGIDQGKVQMW 1723
            + ++  E  + P  H LGP +ERLAL++L  QGLVPEHVE+R LYS  QP I+QGK+QMW
Sbjct: 1766 YSIEEIEAGRIPNPH-LGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMW 1824

Query: 1724 VDIFPKKLGPPGPQVNINPRKPKRKASEHSGHRYELRCIIWKTANVDLVDDNLSREKTSD 1783
            VD+FPK LG PGP  NI PR+ +         R+ LRCIIW T +V L D +L+ EK SD
Sbjct: 1825 VDLFPKALGRPGPPFNITPRRAR---------RFFLRCIIWNTRDVILDDLSLTGEKMSD 1875

Query: 1784 IYIKGWLYGLEKDMQKTDIHYHSLTGEADFNWRFIFTMDYLAAERTCVQSQKDYIWSLDA 1843
            IY+KGW+ G E+  QKTD+HY SL GE +FNWRFIF  DYL AE+ C  ++KD  W LD 
Sbjct: 1876 IYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDK 1935

Query: 1844 TSMKFPARLIIQVWDNDIFSPDDFLGVLELDLSDMPLPARHAKQCSIRMMD--ADPKWPY 1901
            T  K PAR++ Q+WDND FS DDFLG L+LDL+ MP PA+ AK+CS+  +D    P+W  
Sbjct: 1936 TESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEW-- 1993

Query: 1902 FIQYKHFSLFKKKTVTGWWPCQVLDGGKWRLSGKVKMSLEILSEKEALIKPAGRGQSEPN 1961
                   SLF++KTV GWWPC   +G K  L+GK++M+LEI++E E   +PAG+G+ EPN
Sbjct: 1994 -----FVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPN 2048

Query: 1962 QYPTLHPPLRTNTSFTWLRSPVQNFCYIFWKRYRFKLIAFMVISIIALMLFNFIYSAPHY 2021
              P L  P R +TSF W  SP +   +I W+R+R+ +I F+++ I+ L L  FIY+ P+Y
Sbjct: 2049 MNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNY 2108

Query: 2022 LAMSWIKP 2029
             AM  +KP
Sbjct: 2109 AAMKLVKP 2116



 Score = 61.2 bits (147), Expect = 1e-08
 Identities = 41/124 (33%), Positives = 68/124 (54%), Gaps = 3/124 (2%)

Query: 1   MLRLVVQSAK-IDPPLAPLPRPCMSIDFRDIKKRTRVVEGN-DPVWNETLIWHLWNRPLE 58
           MLR+ +  A+ +  P   +     S  F  +KKRT+V++ + +PVWNE   W L   PL+
Sbjct: 1   MLRVFILYAENVHTPDTDISDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLD 60

Query: 59  NDSFLQVTLQDMGSQKKERFIGLATVLLKPLLKQPSEVLFVKDLTLLNHSMKPTDCTVTL 118
             S L V ++D  +  + RF+G A V L+ +L  PS +    +  LL+   +PT  ++ L
Sbjct: 61  QGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPS-LSASFNAPLLDTKKQPTGASLVL 119

Query: 119 QVAH 122
           QV++
Sbjct: 120 QVSY 123



 Score = 40.0 bits (92), Expect = 0.024
 Identities = 24/86 (27%), Positives = 46/86 (53%), Gaps = 1/86 (1%)

Query: 20  RPCMSIDFRDIKKRTRVVEGNDPVWNETLIWHLWNRPLE-NDSFLQVTLQDMGSQKKERF 78
           +P + +      KRTR+ +GN P++NETL ++L++ P E  D  + +T+ D  S + +  
Sbjct: 269 KPVVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDAL 328

Query: 79  IGLATVLLKPLLKQPSEVLFVKDLTL 104
           +G   + +  + ++P      K L L
Sbjct: 329 LGEFRMDVGTIYREPRHAYLRKWLLL 354


>gi|35493853 otoferlin isoform c [Homo sapiens]
          Length = 1307

 Score =  421 bits (1082), Expect = e-117
 Identities = 244/611 (39%), Positives = 351/611 (57%), Gaps = 54/611 (8%)

Query: 1438 LKVYECELEAVPAFQGLQDFCQTFKLYQEQPKLDSP-------VVGEFKGLFRIY--PFP 1488
            LKVY  ELE+   F   +D+  TF L + +   D         +VG FKG   +Y  P P
Sbjct: 718  LKVYPKELES--EFDNFEDWLHTFNLLRGKTGDDEDGSTEEERIVGRFKGSLCVYKVPLP 775

Query: 1489 ENP--EAPKPPLQFLVWPEREDFPQPCLVRVYMVRAINLQPQDYNGLCDPYVILKLGKTE 1546
            E+   EA       +      + P   LVRVY+VRA +L P D NG  DPY+ ++LGKT+
Sbjct: 776  EDVSREAGYDSTYGMFQGIPSNDPINVLVRVYVVRATDLHPADINGKADPYIAIRLGKTD 835

Query: 1547 LGNRDMYQPNTLDPIFGMMFELTCNIPLEKDLEIQLYDFDLFSPDDKIGTTVIDLENRLL 1606
            + +++ Y    L+P+FG  F++  + P+E  L + +YD+DL   DD IG T IDLENR  
Sbjct: 836  IRDKENYISKQLNPVFGKSFDIEASFPMESMLTVAVYDWDLVGTDDLIGETKIDLENRFY 895

Query: 1607 SGFGAHCGLSKSYCQSGPFRWRDQMPPSYLLERYAKRKGLPPPLFSPE-----EDAVFYN 1661
            S   A CG++++Y   G   WRD M PS +L R  K   +  P F P       + VF  
Sbjct: 896  SKHRATCGIAQTYSTHGYNIWRDPMKPSQILTRLCKDGKVDGPHFGPPGRVKVANRVFTG 955

Query: 1662 GKKFKLQSFEPKTPTVHGLGPKKERLALYLL-HTQG-------LVPEHVETRTLYSHSQP 1713
              + + ++ + K        P  E +AL  L H +        LVPEHVETR L +  +P
Sbjct: 956  PSEIEDENGQRK--------PTDEHVALLALRHWEDIPRAGCRLVPEHVETRPLLNPDKP 1007

Query: 1714 GIDQGKVQMWVDIFPKKLGPPGPQVNINPRKPKRKASEHSGHRYELRCIIWKTANVDLVD 1773
            GI+QG++++WVD+FP  +  PG  ++I+PRKPK+         YELR IIW T  V L D
Sbjct: 1008 GIEQGRLELWVDMFPMDMPAPGTPLDISPRKPKK---------YELRVIIWNTDEVVLED 1058

Query: 1774 DNL-SREKTSDIYIKGWLYGLEKDMQKTDIHYHSLTGEADFNWRFIFTMDYLAAERTCVQ 1832
            D+  + EK+SDI+++GWL G ++D Q TD+HYHSLTGE +FNWR++F  DYLAAE   V 
Sbjct: 1059 DDFFTGEKSSDIFVRGWLKGQQEDKQDTDVHYHSLTGEGNFNWRYLFPFDYLAAEEKIVI 1118

Query: 1833 SQKDYIWSLDATSMKFPARLIIQVWDNDIFSPDDFLGVLELDLSDMPLPARHAKQCSIRM 1892
            S+K+ ++S D T  K PARL +Q+WD D FS DDFLG +ELDL+  P  A+ AKQC++ M
Sbjct: 1119 SKKESMFSWDETEYKIPARLTLQIWDADHFSADDFLGAIELDLNRFPRGAKTAKQCTMEM 1178

Query: 1893 MDADPKWPYFIQYKHFSLFKKKTVTGWWPCQVL-DGGKWRLSGKVKMSLEILSEKEALIK 1951
               +   P        S+FK+K V GWWP     +  ++ L+GKV+  L +L+ +EA   
Sbjct: 1179 ATGEVDVPL------VSIFKQKRVKGWWPLLARNENDEFELTGKVEAELHLLTAEEAEKN 1232

Query: 1952 PAGRGQSEPNQYPTLHPPLRTNTSFTWLRSPVQNFCYIFWKRYRFKLIAFMVISIIALML 2011
            P G  ++EP+    L  P R +TSF W  +P+++  Y  W  YR+ L+  +++ ++ L+L
Sbjct: 1233 PVGLARNEPD---PLEKPNRPDTSFIWFLNPLKSARYFLWHTYRWLLLKLLLLLLLLLLL 1289

Query: 2012 FNFIYSAPHYL 2022
              F+YS P YL
Sbjct: 1290 ALFLYSVPGYL 1300



 Score =  143 bits (361), Expect = 2e-33
 Identities = 100/339 (29%), Positives = 170/339 (50%), Gaps = 21/339 (6%)

Query: 1046 GRLSW-VQA-MDLKYHAGKEEDSKTWPWGLDRQFRDPQR-QDTRPPNLPFIYCTFNKPHY 1102
            G   W VQA ++L    G  +  K +  GL   F++ +  Q       P +   + K   
Sbjct: 210  GSAGWTVQAKVELYLWLGLSKQRKEFLCGLPCGFQEVKAAQGLGLHAFPPVSLVYTKKQA 269

Query: 1103 YQLFCYIYQARNLVSNQILTFQGPFIRVVFLNHSQCTQTLRSSAGPTWAQTLIFQHLLLY 1162
            +QL  ++YQAR+L +        PF RV F+N SQCT+ L  +  PTW Q L+F +L LY
Sbjct: 270  FQLRAHMYQARSLFAADSSGLSDPFARVFFINQSQCTEVLNETLCPTWDQMLVFDNLELY 329

Query: 1163 ENPQDTKESPPLVVLELWQRDFWGKESLWGRSVWPPMVWLDLQDRILPPMRWHPLVKEL- 1221
                + ++ PP++V+E++ +D  GK    GR+   P+V   + D    P R+ P ++   
Sbjct: 330  GEAHELRDDPPIIVIEIYDQDSMGKADFMGRTFAKPLV--KMADEAYCPPRFPPQLEYYQ 387

Query: 1222 ----GKEEGEILASCELILQTEKLGEKQLPILSVPW---KNGAYTLPKSIQPTIKRMAIE 1274
                    G++LA+ EL LQ    G+  LP ++ P    +     +P  I+P + +  +E
Sbjct: 388  IYRGNATAGDLLAAFEL-LQIGPAGKADLPPINGPVDVDRGPIMPVPMGIRPVLSKYRVE 446

Query: 1275 ILAWGLRNMKKAS-----SPQLLVEFGEESLRTEPIRDFQTNPNFPESESVLVLTVLMPT 1329
            +L WGLR++K+ +      P++ +E   + +++  I +++ NPNF  +  V    V +P 
Sbjct: 447  VLFWGLRDLKRVNLAQVDRPRVDIECAGKGVQSSLIHNYKKNPNF--NTLVKWFEVDLPE 504

Query: 1330 EEAYALPLVVKVVDNWAFGQQTVTGQANIDFLQPYFCDP 1368
             E    PL ++VVD  AFG+ T+ G   +  L+ +   P
Sbjct: 505  NELLHPPLNIRVVDCRAFGRYTLVGSHAVSSLRRFIYRP 543



 Score = 72.0 bits (175), Expect = 6e-12
 Identities = 41/131 (31%), Positives = 73/131 (55%), Gaps = 11/131 (8%)

Query: 640 TSLDRKRWQLRSLLLQELAQKAKQAKP-------KDMVATAEDWLYRLNTVLPEPQMGLP 692
           T LDR+R +     L+ + Q+A+  +        +D +   +++L +L  +  EPQ  +P
Sbjct: 98  TRLDRERLKSCMRELENMGQQARMLRAQVKRHTVRDKLRLCQNFLQKLRFLADEPQHSIP 157

Query: 693 DVMIWLVAKEQRVAYAQVPAHSVLFSPAGALHSGRLCGKIQTLFLQYPEGEGQKD---VL 749
           D+ IW+++  +RVAYA+VP+  +LFS      +G+ C K++TLFL+ P   G       +
Sbjct: 158 DIFIWMMSNNKRVAYARVPSKDLLFSIVEE-ETGKDCAKVKTLFLKLPGKRGFGSAGWTV 216

Query: 750 PAHLRVCMWLG 760
            A + + +WLG
Sbjct: 217 QAKVELYLWLG 227


>gi|35493868 otoferlin isoform b [Homo sapiens]
          Length = 1230

 Score =  421 bits (1082), Expect = e-117
 Identities = 244/611 (39%), Positives = 351/611 (57%), Gaps = 54/611 (8%)

Query: 1438 LKVYECELEAVPAFQGLQDFCQTFKLYQEQPKLDSP-------VVGEFKGLFRIY--PFP 1488
            LKVY  ELE+   F   +D+  TF L + +   D         +VG FKG   +Y  P P
Sbjct: 641  LKVYPKELES--EFDNFEDWLHTFNLLRGKTGDDEDGSTEEERIVGRFKGSLCVYKVPLP 698

Query: 1489 ENP--EAPKPPLQFLVWPEREDFPQPCLVRVYMVRAINLQPQDYNGLCDPYVILKLGKTE 1546
            E+   EA       +      + P   LVRVY+VRA +L P D NG  DPY+ ++LGKT+
Sbjct: 699  EDVSREAGYDSTYGMFQGIPSNDPINVLVRVYVVRATDLHPADINGKADPYIAIRLGKTD 758

Query: 1547 LGNRDMYQPNTLDPIFGMMFELTCNIPLEKDLEIQLYDFDLFSPDDKIGTTVIDLENRLL 1606
            + +++ Y    L+P+FG  F++  + P+E  L + +YD+DL   DD IG T IDLENR  
Sbjct: 759  IRDKENYISKQLNPVFGKSFDIEASFPMESMLTVAVYDWDLVGTDDLIGETKIDLENRFY 818

Query: 1607 SGFGAHCGLSKSYCQSGPFRWRDQMPPSYLLERYAKRKGLPPPLFSPE-----EDAVFYN 1661
            S   A CG++++Y   G   WRD M PS +L R  K   +  P F P       + VF  
Sbjct: 819  SKHRATCGIAQTYSTHGYNIWRDPMKPSQILTRLCKDGKVDGPHFGPPGRVKVANRVFTG 878

Query: 1662 GKKFKLQSFEPKTPTVHGLGPKKERLALYLL-HTQG-------LVPEHVETRTLYSHSQP 1713
              + + ++ + K        P  E +AL  L H +        LVPEHVETR L +  +P
Sbjct: 879  PSEIEDENGQRK--------PTDEHVALLALRHWEDIPRAGCRLVPEHVETRPLLNPDKP 930

Query: 1714 GIDQGKVQMWVDIFPKKLGPPGPQVNINPRKPKRKASEHSGHRYELRCIIWKTANVDLVD 1773
            GI+QG++++WVD+FP  +  PG  ++I+PRKPK+         YELR IIW T  V L D
Sbjct: 931  GIEQGRLELWVDMFPMDMPAPGTPLDISPRKPKK---------YELRVIIWNTDEVVLED 981

Query: 1774 DNL-SREKTSDIYIKGWLYGLEKDMQKTDIHYHSLTGEADFNWRFIFTMDYLAAERTCVQ 1832
            D+  + EK+SDI+++GWL G ++D Q TD+HYHSLTGE +FNWR++F  DYLAAE   V 
Sbjct: 982  DDFFTGEKSSDIFVRGWLKGQQEDKQDTDVHYHSLTGEGNFNWRYLFPFDYLAAEEKIVI 1041

Query: 1833 SQKDYIWSLDATSMKFPARLIIQVWDNDIFSPDDFLGVLELDLSDMPLPARHAKQCSIRM 1892
            S+K+ ++S D T  K PARL +Q+WD D FS DDFLG +ELDL+  P  A+ AKQC++ M
Sbjct: 1042 SKKESMFSWDETEYKIPARLTLQIWDADHFSADDFLGAIELDLNRFPRGAKTAKQCTMEM 1101

Query: 1893 MDADPKWPYFIQYKHFSLFKKKTVTGWWPCQVL-DGGKWRLSGKVKMSLEILSEKEALIK 1951
               +   P        S+FK+K V GWWP     +  ++ L+GKV+  L +L+ +EA   
Sbjct: 1102 ATGEVDVPL------VSIFKQKRVKGWWPLLARNENDEFELTGKVEAELHLLTAEEAEKN 1155

Query: 1952 PAGRGQSEPNQYPTLHPPLRTNTSFTWLRSPVQNFCYIFWKRYRFKLIAFMVISIIALML 2011
            P G  ++EP+    L  P R +TSF W  +P+++  Y  W  YR+ L+  +++ ++ L+L
Sbjct: 1156 PVGLARNEPD---PLEKPNRPDTSFIWFLNPLKSARYFLWHTYRWLLLKLLLLLLLLLLL 1212

Query: 2012 FNFIYSAPHYL 2022
              F+YS P YL
Sbjct: 1213 ALFLYSVPGYL 1223



 Score =  148 bits (374), Expect = 5e-35
 Identities = 137/507 (27%), Positives = 227/507 (44%), Gaps = 60/507 (11%)

Query: 1046 GRLSW-VQA-MDLKYHAGKEEDSKTWPWGLDRQFRDPQR-QDTRPPNLPFIYCTFNKPHY 1102
            G   W VQA ++L    G  +  K +  GL   F++ +  Q       P +   + K   
Sbjct: 153  GSAGWTVQAKVELYLWLGLSKQRKEFLCGLPCGFQEVKAAQGLGLHAFPPVSLVYTKKQA 212

Query: 1103 YQLFCYIYQARNLVSNQILTFQGPFIRVVFLNHSQCTQTLRSSAGPTWAQTLIFQHLLLY 1162
            +QL  ++YQAR+L +        PF RV F+N SQCT+ L  +  PTW Q L+F +L LY
Sbjct: 213  FQLRAHMYQARSLFAADSSGLSDPFARVFFINQSQCTEVLNETLCPTWDQMLVFDNLELY 272

Query: 1163 ENPQDTKESPPLVVLELWQRDFWGKESLWGRSVWPPMVWLDLQDRILPPMRWHPLVKEL- 1221
                + ++ PP++V+E++ +D  GK    GR+   P+V   + D    P R+ P ++   
Sbjct: 273  GEAHELRDDPPIIVIEIYDQDSMGKADFMGRTFAKPLV--KMADEAYCPPRFPPQLEYYQ 330

Query: 1222 ----GKEEGEILASCELILQTEKLGEKQLPILSVPW---KNGAYTLPKSIQPTIKRMAIE 1274
                    G++LA+ EL LQ    G+  LP ++ P    +     +P  I+P + +  +E
Sbjct: 331  IYRGNATAGDLLAAFEL-LQIGPAGKADLPPINGPVDVDRGPIMPVPMGIRPVLSKYRVE 389

Query: 1275 ILAWGLRNMKKAS-----SPQLLVEFGEESLRTEPIRDFQTNPNFPESESVLVLTVLMPT 1329
            +L WGLR++K+ +      P++ +E   + +++  I +++ NPNF  +  V    V +P 
Sbjct: 390  VLFWGLRDLKRVNLAQVDRPRVDIECAGKGVQSSLIHNYKKNPNF--NTLVKWFEVDLPE 447

Query: 1330 EEAYALPLVVKVVDNWAFGQQTVTGQANIDFLQPYFCDP-------WAQD-----YMHPK 1377
             E    PL ++VVD  AFG+ T+ G   +  L+ +   P       W         M P+
Sbjct: 448  NELLHPPLNIRVVDCRAFGRYTLVGSHAVSSLRRFIYRPPDRSAPSWNTTGEVVVTMEPE 507

Query: 1378 LP------------TLSEKKHQDFLGYLYRKFWFKSSKAEDEYEHE-----VDWWSKLFW 1420
            +P            T       D       K   K   AE+  E E     +DWWSK F 
Sbjct: 508  VPIKKLETMVKLDATSEAVVKVDVAEEEKEKKKKKKGTAEEPEEEEPDESMLDWWSKYFA 567

Query: 1421 ATDEHK-SLKYKYKDYHTLKVYECELEAVPAFQGLQDFCQTFKLYQEQPKLDSPVVGEFK 1479
            + D  K  L+ +      L+  E E++     +G     +  +  +E+ K  +   G  +
Sbjct: 568  SIDTMKEQLRQQEPSGIDLEEKE-EVDNTEGLKGSMKGKEKARAAKEEKKKKTQSSGSGQ 626

Query: 1480 GLFRIYPFPENPEAPKPPLQFL-VWPE 1505
            G        E PE  KP +  L V+P+
Sbjct: 627  G-------SEAPEKKKPKIDELKVYPK 646



 Score = 72.0 bits (175), Expect = 6e-12
 Identities = 41/131 (31%), Positives = 73/131 (55%), Gaps = 11/131 (8%)

Query: 640 TSLDRKRWQLRSLLLQELAQKAKQAKP-------KDMVATAEDWLYRLNTVLPEPQMGLP 692
           T LDR+R +     L+ + Q+A+  +        +D +   +++L +L  +  EPQ  +P
Sbjct: 41  TRLDRERLKSCMRELENMGQQARMLRAQVKRHTVRDKLRLCQNFLQKLRFLADEPQHSIP 100

Query: 693 DVMIWLVAKEQRVAYAQVPAHSVLFSPAGALHSGRLCGKIQTLFLQYPEGEGQKD---VL 749
           D+ IW+++  +RVAYA+VP+  +LFS      +G+ C K++TLFL+ P   G       +
Sbjct: 101 DIFIWMMSNNKRVAYARVPSKDLLFSIVEE-ETGKDCAKVKTLFLKLPGKRGFGSAGWTV 159

Query: 750 PAHLRVCMWLG 760
            A + + +WLG
Sbjct: 160 QAKVELYLWLG 170


>gi|34740331 otoferlin isoform a [Homo sapiens]
          Length = 1997

 Score =  421 bits (1082), Expect = e-117
 Identities = 244/611 (39%), Positives = 351/611 (57%), Gaps = 54/611 (8%)

Query: 1438 LKVYECELEAVPAFQGLQDFCQTFKLYQEQPKLDSP-------VVGEFKGLFRIY--PFP 1488
            LKVY  ELE+   F   +D+  TF L + +   D         +VG FKG   +Y  P P
Sbjct: 1408 LKVYPKELES--EFDNFEDWLHTFNLLRGKTGDDEDGSTEEERIVGRFKGSLCVYKVPLP 1465

Query: 1489 ENP--EAPKPPLQFLVWPEREDFPQPCLVRVYMVRAINLQPQDYNGLCDPYVILKLGKTE 1546
            E+   EA       +      + P   LVRVY+VRA +L P D NG  DPY+ ++LGKT+
Sbjct: 1466 EDVSREAGYDSTYGMFQGIPSNDPINVLVRVYVVRATDLHPADINGKADPYIAIRLGKTD 1525

Query: 1547 LGNRDMYQPNTLDPIFGMMFELTCNIPLEKDLEIQLYDFDLFSPDDKIGTTVIDLENRLL 1606
            + +++ Y    L+P+FG  F++  + P+E  L + +YD+DL   DD IG T IDLENR  
Sbjct: 1526 IRDKENYISKQLNPVFGKSFDIEASFPMESMLTVAVYDWDLVGTDDLIGETKIDLENRFY 1585

Query: 1607 SGFGAHCGLSKSYCQSGPFRWRDQMPPSYLLERYAKRKGLPPPLFSPE-----EDAVFYN 1661
            S   A CG++++Y   G   WRD M PS +L R  K   +  P F P       + VF  
Sbjct: 1586 SKHRATCGIAQTYSTHGYNIWRDPMKPSQILTRLCKDGKVDGPHFGPPGRVKVANRVFTG 1645

Query: 1662 GKKFKLQSFEPKTPTVHGLGPKKERLALYLL-HTQG-------LVPEHVETRTLYSHSQP 1713
              + + ++ + K        P  E +AL  L H +        LVPEHVETR L +  +P
Sbjct: 1646 PSEIEDENGQRK--------PTDEHVALLALRHWEDIPRAGCRLVPEHVETRPLLNPDKP 1697

Query: 1714 GIDQGKVQMWVDIFPKKLGPPGPQVNINPRKPKRKASEHSGHRYELRCIIWKTANVDLVD 1773
            GI+QG++++WVD+FP  +  PG  ++I+PRKPK+         YELR IIW T  V L D
Sbjct: 1698 GIEQGRLELWVDMFPMDMPAPGTPLDISPRKPKK---------YELRVIIWNTDEVVLED 1748

Query: 1774 DNL-SREKTSDIYIKGWLYGLEKDMQKTDIHYHSLTGEADFNWRFIFTMDYLAAERTCVQ 1832
            D+  + EK+SDI+++GWL G ++D Q TD+HYHSLTGE +FNWR++F  DYLAAE   V 
Sbjct: 1749 DDFFTGEKSSDIFVRGWLKGQQEDKQDTDVHYHSLTGEGNFNWRYLFPFDYLAAEEKIVI 1808

Query: 1833 SQKDYIWSLDATSMKFPARLIIQVWDNDIFSPDDFLGVLELDLSDMPLPARHAKQCSIRM 1892
            S+K+ ++S D T  K PARL +Q+WD D FS DDFLG +ELDL+  P  A+ AKQC++ M
Sbjct: 1809 SKKESMFSWDETEYKIPARLTLQIWDADHFSADDFLGAIELDLNRFPRGAKTAKQCTMEM 1868

Query: 1893 MDADPKWPYFIQYKHFSLFKKKTVTGWWPCQVL-DGGKWRLSGKVKMSLEILSEKEALIK 1951
               +   P        S+FK+K V GWWP     +  ++ L+GKV+  L +L+ +EA   
Sbjct: 1869 ATGEVDVPL------VSIFKQKRVKGWWPLLARNENDEFELTGKVEAELHLLTAEEAEKN 1922

Query: 1952 PAGRGQSEPNQYPTLHPPLRTNTSFTWLRSPVQNFCYIFWKRYRFKLIAFMVISIIALML 2011
            P G  ++EP+    L  P R +TSF W  +P+++  Y  W  YR+ L+  +++ ++ L+L
Sbjct: 1923 PVGLARNEPD---PLEKPNRPDTSFIWFLNPLKSARYFLWHTYRWLLLKLLLLLLLLLLL 1979

Query: 2012 FNFIYSAPHYL 2022
              F+YS P YL
Sbjct: 1980 ALFLYSVPGYL 1990



 Score =  214 bits (545), Expect = 7e-55
 Identities = 184/693 (26%), Positives = 314/693 (45%), Gaps = 116/693 (16%)

Query: 161 SSKPQHFQVRVKVFEARQLMGNNIKPVVKVSIAGQQHQTRIKMGNN-PFFNEIFFQNFHE 219
           + +P  +QV + V EARQL+G N+ PVV V +   +  T +K   N P++NE F  +FH 
Sbjct: 248 AGRPMDYQVSITVIEARQLVGLNMDPVVCVEVGDDKKYTSMKESTNCPYYNEYFVFDFHV 307

Query: 220 VPAKFFDETILIQT------------------DIGFIYHSPGHTLLRKWLGLCQPNNPGS 261
            P   FD+ I I                    D+G +Y  P H    KW  L  P++  S
Sbjct: 308 SPDVMFDKIIKISVIHSKNLLRSGTLVGSFKMDVGTVYSQPEHQFHHKWAILSDPDDISS 367

Query: 262 GVTGYLKVTIYALGVGDQALIDQKLLYGTDDTDIQ---IFKSAVVPINM-AYLQLFIYCA 317
           G+ GY+K  +  +G GD      K    TD+ DI+   +    V P    A   + IY A
Sbjct: 368 GLKGYVKCDVAVVGKGDNIKTPHK-ANETDEDDIEGNLLLPEGVPPERQWARFYVKIYRA 426

Query: 318 EDL---------HLKK------HQSVNPQLEVELIGEKLRTHMQTQTDNPIWNQILTFRI 362
           E L         ++KK         V+P ++V   G+K +T +Q  +  P+WN+ + F  
Sbjct: 427 EGLPRMNTSLMANVKKAFIGENKDLVDPYVQVFFAGQKGKTSVQKSSYEPLWNEQVVFTD 486

Query: 363 QLPCLSSYIKFRVLDCRKKDCPDEIGTASLSLNQISSTGEEIEGKQSLEPTSYTPRVYSG 422
             P L   +K ++ D  K +    IGT  + L +IS+ G++                  G
Sbjct: 487 LFPPLCKRMKVQIRDSDKVN-DVAIGTHFIDLRKISNDGDK------------------G 527

Query: 423 FLPCFGPSFLTLHGGKKAPFRIQEEGACIPDSVRDGLAYRGRVFLELITQIKSYQD---- 478
           FLP  GP+++ ++G  +  + + +E   + + + +G+++R R+ L L  +I    +    
Sbjct: 528 FLPTLGPAWVNMYGSTR-NYTLLDEHQDLNEGLGEGVSFRARLLLGLAVEIVDTSNPELT 586

Query: 479 STIKDLSHEVTRIEKH--QNRQKYGLCVIFLSCTMMP--NFKELIHFEVSIGHYGNKMDL 534
           S+ +    + T I +      +++ L   FL  +M+   N  + I FEV+IG+YGN++D 
Sbjct: 587 SSTEVQVEQATPISESCAGKMEEFFLFGAFLEASMIDRRNGDKPITFEVTIGNYGNEVDG 646

Query: 535 NYKP---------------------------------LVSST-PYSPVIYDGNIYHYVPW 560
             +P                                  VSST P  P + D N +H +P+
Sbjct: 647 LSRPQRPRPRKEPGDEEEVDLIQNASDDEAGDAGDLASVSSTPPMRPQVTDRNYFH-LPY 705

Query: 561 YNTKPVVAVTSNWEDVSFRMNCLNLLHFTRDRLKANLDTLKSTRNPKDPALLYQWEKLLR 620
              KP + + S W D   R+   N++    D+L+  L+ ++     +      +   +L 
Sbjct: 706 LERKPCIYIKSWWPDQRRRLYNANIMDHIADKLEEGLNDIQEMIKTEKSYPERRLRGVLE 765

Query: 621 ELAEDCKRPLPCMTY---QPKATSLDRKRWQLRSLLLQELAQKAKQAKP-------KDMV 670
           EL+  C R L            T LDR+R +     L+ + Q+A+  +        +D +
Sbjct: 766 ELSCGCCRFLSLADKDQGHSSRTRLDRERLKSCMRELENMGQQARMLRAQVKRHTVRDKL 825

Query: 671 ATAEDWLYRLNTVLPEPQMGLPDVMIWLVAKEQRVAYAQVPAHSVLFSPAGALHSGRLCG 730
              +++L +L  +  EPQ  +PD+ IW+++  +RVAYA+VP+  +LFS      +G+ C 
Sbjct: 826 RLCQNFLQKLRFLADEPQHSIPDIFIWMMSNNKRVAYARVPSKDLLFSIVEE-ETGKDCA 884

Query: 731 KIQTLFLQYPEGEGQKD---VLPAHLRVCMWLG 760
           K++TLFL+ P   G       + A + + +WLG
Sbjct: 885 KVKTLFLKLPGKRGFGSAGWTVQAKVELYLWLG 917



 Score =  143 bits (361), Expect = 2e-33
 Identities = 100/339 (29%), Positives = 170/339 (50%), Gaps = 21/339 (6%)

Query: 1046 GRLSW-VQA-MDLKYHAGKEEDSKTWPWGLDRQFRDPQR-QDTRPPNLPFIYCTFNKPHY 1102
            G   W VQA ++L    G  +  K +  GL   F++ +  Q       P +   + K   
Sbjct: 900  GSAGWTVQAKVELYLWLGLSKQRKEFLCGLPCGFQEVKAAQGLGLHAFPPVSLVYTKKQA 959

Query: 1103 YQLFCYIYQARNLVSNQILTFQGPFIRVVFLNHSQCTQTLRSSAGPTWAQTLIFQHLLLY 1162
            +QL  ++YQAR+L +        PF RV F+N SQCT+ L  +  PTW Q L+F +L LY
Sbjct: 960  FQLRAHMYQARSLFAADSSGLSDPFARVFFINQSQCTEVLNETLCPTWDQMLVFDNLELY 1019

Query: 1163 ENPQDTKESPPLVVLELWQRDFWGKESLWGRSVWPPMVWLDLQDRILPPMRWHPLVKEL- 1221
                + ++ PP++V+E++ +D  GK    GR+   P+V   + D    P R+ P ++   
Sbjct: 1020 GEAHELRDDPPIIVIEIYDQDSMGKADFMGRTFAKPLV--KMADEAYCPPRFPPQLEYYQ 1077

Query: 1222 ----GKEEGEILASCELILQTEKLGEKQLPILSVPW---KNGAYTLPKSIQPTIKRMAIE 1274
                    G++LA+ EL LQ    G+  LP ++ P    +     +P  I+P + +  +E
Sbjct: 1078 IYRGNATAGDLLAAFEL-LQIGPAGKADLPPINGPVDVDRGPIMPVPMGIRPVLSKYRVE 1136

Query: 1275 ILAWGLRNMKKAS-----SPQLLVEFGEESLRTEPIRDFQTNPNFPESESVLVLTVLMPT 1329
            +L WGLR++K+ +      P++ +E   + +++  I +++ NPNF  +  V    V +P 
Sbjct: 1137 VLFWGLRDLKRVNLAQVDRPRVDIECAGKGVQSSLIHNYKKNPNF--NTLVKWFEVDLPE 1194

Query: 1330 EEAYALPLVVKVVDNWAFGQQTVTGQANIDFLQPYFCDP 1368
             E    PL ++VVD  AFG+ T+ G   +  L+ +   P
Sbjct: 1195 NELLHPPLNIRVVDCRAFGRYTLVGSHAVSSLRRFIYRP 1233


>gi|119120884 fer-1-like 6 [Homo sapiens]
          Length = 1857

 Score =  418 bits (1075), Expect = e-116
 Identities = 248/678 (36%), Positives = 362/678 (53%), Gaps = 88/678 (12%)

Query: 1400 KSSKAEDEYEHEVDWWSKLFWATDE----------------------------------- 1424
            K + A++  E+ +DWWSK + +  +                                   
Sbjct: 1199 KRTIADESAENVIDWWSKYYASLKKAQKAKERNPKGKKGNTEAKPDEVVVDIEDGPKKKK 1258

Query: 1425 HKSLKYKYKD-----YHTLKVYECELEAVPAFQGLQDFCQTFKLYQEQPKLDSP------ 1473
             K LK K KD        L++Y+ +LE+   F   +D+ +TF+L++ +   D        
Sbjct: 1259 DKMLKKKPKDDGIPNLAILQIYDGDLES--EFNNFEDWVKTFELFRGKSTEDDHGLDGDR 1316

Query: 1474 VVGEFKGLFRIYPFPENPEAPKPPLQFLVWPEREDFPQPCLVRVYMVRAINLQPQDYNGL 1533
            V+G+FKG F IY  P++  +       +      + P   L+RVY+V A NL P D +G 
Sbjct: 1317 VIGKFKGSFCIYKSPQDSSSEDSGQLRIQQGIPPNHPVTVLIRVYIVAAFNLSPADPDGK 1376

Query: 1534 CDPYVILKLGKTELGNRDMYQPNTLDPIFGMMFELTCNIPLEKDLEIQLYDFDLFSPDDK 1593
             DPY+++KLGKTE+ +RD Y P  L+P+FG  FE+    P E  L I +YD D+   DD 
Sbjct: 1377 SDPYIVIKLGKTEIKDRDKYIPKQLNPVFGRSFEIQATFPKESLLSILIYDHDMIGTDDL 1436

Query: 1594 IGTTVIDLENRLLSGFGAHCGLSKSYCQSGPFRWRDQMPPSYLLERYAKRKGLPPPLFSP 1653
            IG T IDLENR  S   A CGL   Y   G   WRD   P+ +L +  K   L  P F P
Sbjct: 1437 IGETKIDLENRFYSKHRAICGLQSQYEIEGYNAWRDTSKPTEILTKLCKDNKLDGPYFHP 1496

Query: 1654 EEDAV---FYNGKKFKLQSFEPKTPTVHGLGPKKERLALYLLHTQG--------LVPEHV 1702
             +  +    ++GK    +    +T   +      E LAL +LH+          LVPEH+
Sbjct: 1497 GKIQIGNQVFSGKTIFTEEDTDETVESY------EHLALKVLHSWEDIPEVGCRLVPEHI 1550

Query: 1703 ETRTLYSHSQPGIDQGKVQMWVDIFPKKLGPPGPQVNINPRKPKRKASEHSGHRYELRCI 1762
            ETR LY   +PG++QG++QMWVD+FPK +  PGP V+I+PR+PK          YELR  
Sbjct: 1551 ETRPLYHKDKPGMEQGRLQMWVDMFPKDMPQPGPPVDISPRRPKG---------YELRVT 1601

Query: 1763 IWKTANVDLVDDNL-SREKTSDIYIKGWLYGLEKDMQKTDIHYHSLTGEADFNWRFIFTM 1821
            IW T +V L D+N+ + +K+SDIY+KGWL GLE D Q+TD+HY+SLTGE +FNWRF+F  
Sbjct: 1602 IWNTEDVILEDENIFTGQKSSDIYVKGWLKGLEDDKQETDVHYNSLTGEGNFNWRFLFPF 1661

Query: 1822 DYLAAERTCVQSQKDYIWSLDATSMKFPARLIIQVWDNDIFSPDDFLGVLELDLSDMPLP 1881
             YL AE+  V ++++ I+SL+    K PA L++QVWD +  S DDFLG LE++L+  P  
Sbjct: 1662 QYLPAEKQMVITKRENIFSLEKMECKTPAVLVLQVWDFERLSSDDFLGTLEMNLNSFPRA 1721

Query: 1882 ARHAKQCSIRMMDADPKWPYFIQYKHFSLFKKKTVTGWWPCQVLDGGKWRLSGKVKMSLE 1941
            A+ AK C +       K+    +    S+F++K V GWWP          L+GKV+    
Sbjct: 1722 AKSAKACDL------AKFENASEETKISIFQQKRVRGWWPF----SKSKELTGKVEAEFH 1771

Query: 1942 ILSEKEALIKPAGRGQSEPNQYPTLHPPLRTNTSFTWLRSPVQNFCYIFWKRYRFKLIAF 2001
            +++ +EA   P G+ + EP     L  P R +TSF+W  SP +   Y+ WK Y+  +I  
Sbjct: 1772 LVTAEEAEKNPVGKARKEPE---PLAKPNRPDTSFSWFMSPFKCLYYLIWKNYKKYIIIA 1828

Query: 2002 MVISIIALMLFNFIYSAP 2019
             ++ I+ + L  FIY+ P
Sbjct: 1829 FILIILIIFLVLFIYTLP 1846



 Score =  211 bits (536), Expect = 8e-54
 Identities = 187/732 (25%), Positives = 327/732 (44%), Gaps = 156/732 (21%)

Query: 163 KPQHFQVRVKVFEARQLMGNNIKPVVKVSIAGQQHQTRIKMG-NNPFFNEIFFQNFHEVP 221
           + Q++Q+ + + EARQL+G NI PVV + I  ++ Q+ +K G N+PF+NE F  +F    
Sbjct: 79  RSQNYQIAITITEARQLVGENIDPVVTIEIGDEKKQSTVKEGTNSPFYNEYFVFDFIGPQ 138

Query: 222 AKFFDETILI----------------QTDIGFIYHSPGHTLLRKWLGLCQPNNPGSGVTG 265
              FD+ I I                + D+G +Y+ PGH    KW  L  P +  +G  G
Sbjct: 139 VHLFDKIIKISVFHHKLIGSVLIGSFKVDLGTVYNQPGHQFCNKWALLTDPGDIRTGTKG 198

Query: 266 YLKVTIYALGVGDQALIDQKLLYGTDDTDIQIFKSAVVPINM------AYLQLFIYCAED 319
           YLK  I  +G GD      K    T DT+  I K+ ++P         A   + +Y AE 
Sbjct: 199 YLKCDISVMGKGDVLKTSPK----TSDTEEPIEKNLLIPNGFPLERPWARFYVRLYKAEG 254

Query: 320 LHLKKHQS----------------VNPQLEVELIGEKLRTHMQTQTDNPIWNQILTFRIQ 363
           L  K + S                V+P +EV   G+  RT +Q    +P+W++ + F+  
Sbjct: 255 LP-KMNSSIMANVTKAFVGDSKDLVDPFVEVSFAGQMGRTTVQKNCADPVWHEQVIFKEM 313

Query: 364 LPCLSSYIKFRVLDCRKKDCPDEIGTASLSLNQISSTGEEIEGKQSLEPTSYTPRVYSGF 423
            P L   +K +V D    +    + T  + L +IS+   E +G +             GF
Sbjct: 314 FPPLCRRVKIQVWDEGSMN-DVALATHFIDLKKISN---EQDGDK-------------GF 356

Query: 424 LPCFGPSFLTLHGGKKAPFRIQEEGACIPDSVRDGLAYRGRVFLELITQI---------- 473
           LP FGP+++ L+G  +    + ++   + +   +G+++RGR+ +E+  +I          
Sbjct: 357 LPTFGPAWINLYGSPR-NHSLMDDYQEMNEGFGEGVSFRGRILVEIAVEILSGRAQESKF 415

Query: 474 -------------KSYQDSTIKDLSHEV--------------TRIEKH----------QN 496
                        K  + S  KD + +               T +E            + 
Sbjct: 416 SKALKELKLPSKDKDSKSSKGKDKADKTEDGKSQQASNKTNSTEVEVESFDVPPEIVPEK 475

Query: 497 RQKYGLCVIFLSCTMMPN--FKELIHFEVSIGHYGNKMDLNYK----------------- 537
            +++ L   F   TM+      + I FEVSIG++GN +D                     
Sbjct: 476 NEEFLLFGAFFEATMIDRKIGDKPISFEVSIGNFGNLIDGGSHHGSKKSAESAEEDLLPL 535

Query: 538 --------------PLVSST-PYSPVIYDGN-IYHYVPWYNTKPVVAVTSNWEDVSFRMN 581
                         P+ S+T P  P++ +GN  Y+Y+P+   KP V   S+W D +FR++
Sbjct: 536 LHEGQGDVAHDVPIPMASTTHPEKPLVTEGNRNYNYLPFEAKKPCVYFISSWGDQTFRLH 595

Query: 582 CLNLLHFTRDRLKANLDTLKSTRNPKDPALLYQWEKLLRELAEDCKRPLPCMTYQPK--- 638
             N+L    D L+ +++ ++        A   + + +L +        +     +PK   
Sbjct: 596 WSNMLEKMADFLEESIEEVRELIKISQEAPEEKMKTVLSDFISRSSAFISEAEKKPKMLN 655

Query: 639 ATSLDRKR----WQLRSLLLQE----LAQKAKQAKPKDMVATAEDWLYRLNTVLPEPQMG 690
            T+LD+KR    WQ    + +E    + Q+ K+    +M+  A++++ ++  ++ EPQ  
Sbjct: 656 QTTLDKKRLTLCWQELEAMCKEAKGIIQQQKKKLSVDEMIHEAQNFVEKIRFLVDEPQHT 715

Query: 691 LPDVMIWLVAKEQRVAYAQVPAHSVLFSPAGALHSGRLCGKIQTLFLQYPEGEGQKDVLP 750
           +PDV IW+++  +RVAYA++ +  +L+SP  A   G+ CGKI+T FL+ P        + 
Sbjct: 716 IPDVFIWMLSNNRRVAYARIASKDLLYSPV-AGQMGKHCGKIKTHFLKPPGKRPAGWSVQ 774

Query: 751 AHLRVCMWLGNV 762
           A + V +WLG++
Sbjct: 775 AKVDVYLWLGSI 786



 Score =  159 bits (402), Expect = 3e-38
 Identities = 96/275 (34%), Positives = 149/275 (54%), Gaps = 9/275 (3%)

Query: 1097 FNKPHYYQLFCYIYQARNLVSNQILTFQGPFIRVVFLNHSQCTQTLRSSAGPTWAQTLIF 1156
            + + H +QL  ++YQAR L++        PF +V FL+H Q T+ +  +  PTW Q L+F
Sbjct: 820  YQEQHVFQLRAHMYQARGLIAADSNGLSDPFAKVTFLSHCQTTKIISQTLSPTWNQMLLF 879

Query: 1157 QHLLLYENPQDTKESPPLVVLELWQRDFWGKESLWGRSVWPPMVWLDLQDRILPPMRWHP 1216
              L+L+ + ++  ESPPLVV+EL+  D  GK    G +V  P+V L  QD   P + +HP
Sbjct: 880  NDLVLHGDVKELAESPPLVVVELYDSDAVGKPEYLGATVAAPVVKLADQDYEPPRLCYHP 939

Query: 1217 LVKELGKEEGEILASCELILQTEKLGEKQLPILSVPWKNGAYTLPKSIQPTIKRMAIEIL 1276
            +        G++LA  EL LQ    G + LP +  P     Y +P +I+P + +  +E+L
Sbjct: 940  IFCG-NLSGGDLLAVFEL-LQVPPSGLQGLPPVEPPDITQIYPVPANIRPVLSKYRVEVL 997

Query: 1277 AWGLRNMKK-----ASSPQLLVEFGEESLRTEPIRDFQTNPNFPESESVLVLTVLMPTEE 1331
             WG+R MKK        PQ L+E G + +++  I+ ++ NPNF  S       V +P  E
Sbjct: 998  FWGVREMKKVQLLSVDRPQALIECGGQGVKSCVIQSYKNNPNF--SIQADAFEVELPENE 1055

Query: 1332 AYALPLVVKVVDNWAFGQQTVTGQANIDFLQPYFC 1366
                PL + VVD  AFG+ T+ G   I++L+ + C
Sbjct: 1056 LLHPPLSICVVDWRAFGRSTLVGTYTINYLKQFLC 1090


>gi|35493860 otoferlin isoform d [Homo sapiens]
          Length = 1230

 Score =  414 bits (1063), Expect = e-115
 Identities = 242/611 (39%), Positives = 350/611 (57%), Gaps = 54/611 (8%)

Query: 1438 LKVYECELEAVPAFQGLQDFCQTFKLYQEQPKLDSP-------VVGEFKGLFRIY--PFP 1488
            LKVY  ELE+   F   +D+  TF L + +   D         +VG FKG   +Y  P P
Sbjct: 641  LKVYPKELES--EFDNFEDWLHTFNLLRGKTGDDEDGSTEEERIVGRFKGSLCVYKVPLP 698

Query: 1489 ENP--EAPKPPLQFLVWPEREDFPQPCLVRVYMVRAINLQPQDYNGLCDPYVILKLGKTE 1546
            E+   EA       +      + P   LVRVY+VRA +L P D NG  DPY+ ++LGKT+
Sbjct: 699  EDVSREAGYDSTYGMFQGIPSNDPINVLVRVYVVRATDLHPADINGKADPYIAIRLGKTD 758

Query: 1547 LGNRDMYQPNTLDPIFGMMFELTCNIPLEKDLEIQLYDFDLFSPDDKIGTTVIDLENRLL 1606
            + +++ Y    L+P+FG  F++  + P+E  L + +YD+DL   DD IG T IDLENR  
Sbjct: 759  IRDKENYISKQLNPVFGKSFDIEASFPMESMLTVAVYDWDLVGTDDLIGETKIDLENRFY 818

Query: 1607 SGFGAHCGLSKSYCQSGPFRWRDQMPPSYLLERYAKRKGLPPPLFSPE-----EDAVFYN 1661
            S   A CG++++Y   G   WRD M PS +L R  K   +  P F P       + VF  
Sbjct: 819  SKHRATCGIAQTYSTHGYNIWRDPMKPSQILTRLCKDGKVDGPHFGPPGRVKVANRVFTG 878

Query: 1662 GKKFKLQSFEPKTPTVHGLGPKKERLALYLL-HTQG-------LVPEHVETRTLYSHSQP 1713
              + + ++ + K        P  E +AL  L H +        LVPEHVETR L +  +P
Sbjct: 879  PSEIEDENGQRK--------PTDEHVALLALRHWEDIPRAGCRLVPEHVETRPLLNPDKP 930

Query: 1714 GIDQGKVQMWVDIFPKKLGPPGPQVNINPRKPKRKASEHSGHRYELRCIIWKTANVDLVD 1773
            GI+QG++++WVD+FP  +  PG  ++I+PRKPK+         YELR IIW T  V L D
Sbjct: 931  GIEQGRLELWVDMFPMDMPAPGTPLDISPRKPKK---------YELRVIIWNTDEVVLED 981

Query: 1774 DNL-SREKTSDIYIKGWLYGLEKDMQKTDIHYHSLTGEADFNWRFIFTMDYLAAERTCVQ 1832
            D+  + EK+SDI+++GWL G ++D Q TD+HYHSLTGE +FNWR++F  DYLAAE   V 
Sbjct: 982  DDFFTGEKSSDIFVRGWLKGQQEDKQDTDVHYHSLTGEGNFNWRYLFPFDYLAAEEKIVI 1041

Query: 1833 SQKDYIWSLDATSMKFPARLIIQVWDNDIFSPDDFLGVLELDLSDMPLPARHAKQCSIRM 1892
            S+K+ ++S D T  K PARL +Q+WD D FS DDFLG +ELDL+  P  A+ AKQC++ M
Sbjct: 1042 SKKESMFSWDETEYKIPARLTLQIWDADHFSADDFLGAIELDLNRFPRGAKTAKQCTMEM 1101

Query: 1893 MDADPKWPYFIQYKHFSLFKKKTVTGWWPCQVL-DGGKWRLSGKVKMSLEILSEKEALIK 1951
               +   P        S+FK+K V GWWP     +  ++ L+GKV+  L +L+ +EA   
Sbjct: 1102 ATGEVDVPL------VSIFKQKRVKGWWPLLARNENDEFELTGKVEAELHLLTAEEAEKN 1155

Query: 1952 PAGRGQSEPNQYPTLHPPLRTNTSFTWLRSPVQNFCYIFWKRYRFKLIAFMVISIIALML 2011
            P G  ++EP+    L  P R +T+F W  +P+++  Y+   RY++ +I  ++  +  LML
Sbjct: 1156 PVGLARNEPD---PLEKPNRPDTAFVWFLNPLKSIKYLICTRYKWLIIKIVLALLGLLML 1212

Query: 2012 FNFIYSAPHYL 2022
              F+YS P Y+
Sbjct: 1213 GLFLYSLPGYM 1223



 Score =  148 bits (374), Expect = 5e-35
 Identities = 137/507 (27%), Positives = 227/507 (44%), Gaps = 60/507 (11%)

Query: 1046 GRLSW-VQA-MDLKYHAGKEEDSKTWPWGLDRQFRDPQR-QDTRPPNLPFIYCTFNKPHY 1102
            G   W VQA ++L    G  +  K +  GL   F++ +  Q       P +   + K   
Sbjct: 153  GSAGWTVQAKVELYLWLGLSKQRKEFLCGLPCGFQEVKAAQGLGLHAFPPVSLVYTKKQA 212

Query: 1103 YQLFCYIYQARNLVSNQILTFQGPFIRVVFLNHSQCTQTLRSSAGPTWAQTLIFQHLLLY 1162
            +QL  ++YQAR+L +        PF RV F+N SQCT+ L  +  PTW Q L+F +L LY
Sbjct: 213  FQLRAHMYQARSLFAADSSGLSDPFARVFFINQSQCTEVLNETLCPTWDQMLVFDNLELY 272

Query: 1163 ENPQDTKESPPLVVLELWQRDFWGKESLWGRSVWPPMVWLDLQDRILPPMRWHPLVKEL- 1221
                + ++ PP++V+E++ +D  GK    GR+   P+V   + D    P R+ P ++   
Sbjct: 273  GEAHELRDDPPIIVIEIYDQDSMGKADFMGRTFAKPLV--KMADEAYCPPRFPPQLEYYQ 330

Query: 1222 ----GKEEGEILASCELILQTEKLGEKQLPILSVPW---KNGAYTLPKSIQPTIKRMAIE 1274
                    G++LA+ EL LQ    G+  LP ++ P    +     +P  I+P + +  +E
Sbjct: 331  IYRGNATAGDLLAAFEL-LQIGPAGKADLPPINGPVDVDRGPIMPVPMGIRPVLSKYRVE 389

Query: 1275 ILAWGLRNMKKAS-----SPQLLVEFGEESLRTEPIRDFQTNPNFPESESVLVLTVLMPT 1329
            +L WGLR++K+ +      P++ +E   + +++  I +++ NPNF  +  V    V +P 
Sbjct: 390  VLFWGLRDLKRVNLAQVDRPRVDIECAGKGVQSSLIHNYKKNPNF--NTLVKWFEVDLPE 447

Query: 1330 EEAYALPLVVKVVDNWAFGQQTVTGQANIDFLQPYFCDP-------WAQD-----YMHPK 1377
             E    PL ++VVD  AFG+ T+ G   +  L+ +   P       W         M P+
Sbjct: 448  NELLHPPLNIRVVDCRAFGRYTLVGSHAVSSLRRFIYRPPDRSAPSWNTTGEVVVTMEPE 507

Query: 1378 LP------------TLSEKKHQDFLGYLYRKFWFKSSKAEDEYEHE-----VDWWSKLFW 1420
            +P            T       D       K   K   AE+  E E     +DWWSK F 
Sbjct: 508  VPIKKLETMVKLDATSEAVVKVDVAEEEKEKKKKKKGTAEEPEEEEPDESMLDWWSKYFA 567

Query: 1421 ATDEHK-SLKYKYKDYHTLKVYECELEAVPAFQGLQDFCQTFKLYQEQPKLDSPVVGEFK 1479
            + D  K  L+ +      L+  E E++     +G     +  +  +E+ K  +   G  +
Sbjct: 568  SIDTMKEQLRQQEPSGIDLEEKE-EVDNTEGLKGSMKGKEKARAAKEEKKKKTQSSGSGQ 626

Query: 1480 GLFRIYPFPENPEAPKPPLQFL-VWPE 1505
            G        E PE  KP +  L V+P+
Sbjct: 627  G-------SEAPEKKKPKIDELKVYPK 646



 Score = 72.0 bits (175), Expect = 6e-12
 Identities = 41/131 (31%), Positives = 73/131 (55%), Gaps = 11/131 (8%)

Query: 640 TSLDRKRWQLRSLLLQELAQKAKQAKP-------KDMVATAEDWLYRLNTVLPEPQMGLP 692
           T LDR+R +     L+ + Q+A+  +        +D +   +++L +L  +  EPQ  +P
Sbjct: 41  TRLDRERLKSCMRELENMGQQARMLRAQVKRHTVRDKLRLCQNFLQKLRFLADEPQHSIP 100

Query: 693 DVMIWLVAKEQRVAYAQVPAHSVLFSPAGALHSGRLCGKIQTLFLQYPEGEGQKD---VL 749
           D+ IW+++  +RVAYA+VP+  +LFS      +G+ C K++TLFL+ P   G       +
Sbjct: 101 DIFIWMMSNNKRVAYARVPSKDLLFSIVEE-ETGKDCAKVKTLFLKLPGKRGFGSAGWTV 159

Query: 750 PAHLRVCMWLG 760
            A + + +WLG
Sbjct: 160 QAKVELYLWLG 170


>gi|28376627 synaptotagmin IX [Homo sapiens]
          Length = 491

 Score = 48.9 bits (115), Expect = 5e-05
 Identities = 29/83 (34%), Positives = 44/83 (53%), Gaps = 3/83 (3%)

Query: 1521 RAINLQPQDYNGLCDPYV-ILKLGKTELGNRDMYQPNTLDPIFG--MMFELTCNIPLEKD 1577
            +A+NL  +D++G  DPYV I  L   +  ++      TL+P+F    +F +  N    + 
Sbjct: 243  KAVNLPAKDFSGTSDPYVKIYLLPDRKTKHQTKVHRKTLNPVFDEVFLFPVPYNDLEARK 302

Query: 1578 LEIQLYDFDLFSPDDKIGTTVID 1600
            L   +YDFD FS  D IG  V+D
Sbjct: 303  LHFSVYDFDRFSRHDLIGQVVVD 325



 Score = 33.5 bits (75), Expect = 2.2
 Identities = 23/91 (25%), Positives = 45/91 (49%), Gaps = 5/91 (5%)

Query: 1517 VYMVRAINLQPQDYNGLCDPYVILKL---GKTELGNRDMYQPNTLDPIF--GMMFELTCN 1571
            + +++A NL+  D  G  DPYV + L   G+     +   + NTL+P++   ++F++   
Sbjct: 371  ITIIKARNLKAMDITGASDPYVKVSLMCDGRRLKKRKTSTKRNTLNPVYNEAIVFDVPPE 430

Query: 1572 IPLEKDLEIQLYDFDLFSPDDKIGTTVIDLE 1602
               +  L I + D+D    ++ IG   +  E
Sbjct: 431  NIDQIHLSIAVMDYDRVGHNEIIGVCQVGNE 461


>gi|238550198 synaptotagmin III [Homo sapiens]
          Length = 590

 Score = 48.5 bits (114), Expect = 7e-05
 Identities = 31/89 (34%), Positives = 48/89 (53%), Gaps = 7/89 (7%)

Query: 1517 VYMVRAINLQPQDYNGLCDPYV-ILKLGKTELGNRDMYQPNTLDPIFGMMFELTCNIPL- 1574
            V +++A++L  +D NG  DPYV I  L   +   +      TL+P+F   F+ +  +PL 
Sbjct: 318  VRILQALDLPAKDSNGFSDPYVKIYLLPDRKKKFQTKVHRKTLNPVFNETFQFS--VPLA 375

Query: 1575 ---EKDLEIQLYDFDLFSPDDKIGTTVID 1600
               ++ L   +YDFD FS  D IG  V+D
Sbjct: 376  ELAQRKLHFSVYDFDRFSRHDLIGQVVLD 404



 Score = 35.8 bits (81), Expect = 0.45
 Identities = 22/84 (26%), Positives = 41/84 (48%), Gaps = 5/84 (5%)

Query: 1517 VYMVRAINLQPQDYNGLCDPYV---ILKLGKTELGNRDMYQPNTLDPIF--GMMFELTCN 1571
            V +++A NL+  D  G  DPYV   ++  G+     +   + NTL+P +   ++F++   
Sbjct: 450  VTIIKASNLKAMDLTGFSDPYVKASLISEGRRLKKRKTSIKKNTLNPTYNEALVFDVAPE 509

Query: 1572 IPLEKDLEIQLYDFDLFSPDDKIG 1595
                  L I + D+D    ++ IG
Sbjct: 510  SVENVGLSIAVVDYDCIGHNEVIG 533


>gi|238550196 synaptotagmin III [Homo sapiens]
          Length = 590

 Score = 48.5 bits (114), Expect = 7e-05
 Identities = 31/89 (34%), Positives = 48/89 (53%), Gaps = 7/89 (7%)

Query: 1517 VYMVRAINLQPQDYNGLCDPYV-ILKLGKTELGNRDMYQPNTLDPIFGMMFELTCNIPL- 1574
            V +++A++L  +D NG  DPYV I  L   +   +      TL+P+F   F+ +  +PL 
Sbjct: 318  VRILQALDLPAKDSNGFSDPYVKIYLLPDRKKKFQTKVHRKTLNPVFNETFQFS--VPLA 375

Query: 1575 ---EKDLEIQLYDFDLFSPDDKIGTTVID 1600
               ++ L   +YDFD FS  D IG  V+D
Sbjct: 376  ELAQRKLHFSVYDFDRFSRHDLIGQVVLD 404



 Score = 35.8 bits (81), Expect = 0.45
 Identities = 22/84 (26%), Positives = 41/84 (48%), Gaps = 5/84 (5%)

Query: 1517 VYMVRAINLQPQDYNGLCDPYV---ILKLGKTELGNRDMYQPNTLDPIF--GMMFELTCN 1571
            V +++A NL+  D  G  DPYV   ++  G+     +   + NTL+P +   ++F++   
Sbjct: 450  VTIIKASNLKAMDLTGFSDPYVKASLISEGRRLKKRKTSIKKNTLNPTYNEALVFDVAPE 509

Query: 1572 IPLEKDLEIQLYDFDLFSPDDKIG 1595
                  L I + D+D    ++ IG
Sbjct: 510  SVENVGLSIAVVDYDCIGHNEVIG 533


>gi|14150054 synaptotagmin III [Homo sapiens]
          Length = 590

 Score = 48.5 bits (114), Expect = 7e-05
 Identities = 31/89 (34%), Positives = 48/89 (53%), Gaps = 7/89 (7%)

Query: 1517 VYMVRAINLQPQDYNGLCDPYV-ILKLGKTELGNRDMYQPNTLDPIFGMMFELTCNIPL- 1574
            V +++A++L  +D NG  DPYV I  L   +   +      TL+P+F   F+ +  +PL 
Sbjct: 318  VRILQALDLPAKDSNGFSDPYVKIYLLPDRKKKFQTKVHRKTLNPVFNETFQFS--VPLA 375

Query: 1575 ---EKDLEIQLYDFDLFSPDDKIGTTVID 1600
               ++ L   +YDFD FS  D IG  V+D
Sbjct: 376  ELAQRKLHFSVYDFDRFSRHDLIGQVVLD 404



 Score = 35.8 bits (81), Expect = 0.45
 Identities = 22/84 (26%), Positives = 41/84 (48%), Gaps = 5/84 (5%)

Query: 1517 VYMVRAINLQPQDYNGLCDPYV---ILKLGKTELGNRDMYQPNTLDPIF--GMMFELTCN 1571
            V +++A NL+  D  G  DPYV   ++  G+     +   + NTL+P +   ++F++   
Sbjct: 450  VTIIKASNLKAMDLTGFSDPYVKASLISEGRRLKKRKTSIKKNTLNPTYNEALVFDVAPE 509

Query: 1572 IPLEKDLEIQLYDFDLFSPDDKIG 1595
                  L I + D+D    ++ IG
Sbjct: 510  SVENVGLSIAVVDYDCIGHNEVIG 533


>gi|103472031 family with sequence similarity 62 (C2 domain
            containing), member C [Homo sapiens]
          Length = 886

 Score = 44.7 bits (104), Expect = 0.001
 Identities = 32/98 (32%), Positives = 50/98 (51%), Gaps = 8/98 (8%)

Query: 1509 FPQPC-LVRVYMVRAINLQPQD----YNGLCDPYVILKLGKTELGNRDMYQPNTLDPIFG 1563
            FP PC ++RV+++ A  L  +D      G  DPY  + +G     +R +Y+   L+P + 
Sbjct: 301  FPLPCGVIRVHLLEAEQLAQKDNFLGLRGKSDPYAKVSIGLQHFRSRTIYR--NLNPTWN 358

Query: 1564 MMFELTCNIPLEKDLEIQLYDFDLFSPDDKIGTTVIDL 1601
             +FE        +DLE+ LYD D    DD +G+  I L
Sbjct: 359  EVFEFMVYEVPGQDLEVDLYDEDT-DRDDFLGSLQICL 395


>gi|209447073 synaptotagmin I [Homo sapiens]
          Length = 422

 Score = 44.3 bits (103), Expect = 0.001
 Identities = 49/200 (24%), Positives = 77/200 (38%), Gaps = 29/200 (14%)

Query: 1417 KLFWATDEHKSLKYKYKDYHTLKVYECELEAVPAFQGLQDFCQTFKLYQEQPKLDSPVVG 1476
            K F      K+L   + +  T KV   EL        + DF +  K           ++G
Sbjct: 192  KKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSK---------HDIIG 242

Query: 1477 EFKGLFRIYPFPENPEAPKPPLQFLVWPEREDFPQPCL----------VRVYMVRAINLQ 1526
            EFK       F    E  +  LQ     E+E     C           + V ++ A NL+
Sbjct: 243  EFKVPMNTVDFGHVTEEWRD-LQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLK 301

Query: 1527 PQDYNGLCDPYV---ILKLGKTELGNRDMYQPNTLDPIFGMMFELTCNIPLEKDLEIQ-- 1581
              D  GL DPYV   +++ GK     +   + NTL+P +   F     +P E+  ++Q  
Sbjct: 302  KMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSF--EVPFEQIQKVQVV 359

Query: 1582 --LYDFDLFSPDDKIGTTVI 1599
              + D+D    +D IG   +
Sbjct: 360  VTVLDYDKIGKNDAIGKVFV 379


>gi|5032139 synaptotagmin I [Homo sapiens]
          Length = 422

 Score = 44.3 bits (103), Expect = 0.001
 Identities = 49/200 (24%), Positives = 77/200 (38%), Gaps = 29/200 (14%)

Query: 1417 KLFWATDEHKSLKYKYKDYHTLKVYECELEAVPAFQGLQDFCQTFKLYQEQPKLDSPVVG 1476
            K F      K+L   + +  T KV   EL        + DF +  K           ++G
Sbjct: 192  KKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSK---------HDIIG 242

Query: 1477 EFKGLFRIYPFPENPEAPKPPLQFLVWPEREDFPQPCL----------VRVYMVRAINLQ 1526
            EFK       F    E  +  LQ     E+E     C           + V ++ A NL+
Sbjct: 243  EFKVPMNTVDFGHVTEEWRD-LQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLK 301

Query: 1527 PQDYNGLCDPYV---ILKLGKTELGNRDMYQPNTLDPIFGMMFELTCNIPLEKDLEIQ-- 1581
              D  GL DPYV   +++ GK     +   + NTL+P +   F     +P E+  ++Q  
Sbjct: 302  KMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSF--EVPFEQIQKVQVV 359

Query: 1582 --LYDFDLFSPDDKIGTTVI 1599
              + D+D    +D IG   +
Sbjct: 360  VTVLDYDKIGKNDAIGKVFV 379


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.137    0.439 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 89,341,052
Number of Sequences: 37866
Number of extensions: 4428443
Number of successful extensions: 10152
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 40
Number of HSP's successfully gapped in prelim test: 60
Number of HSP's that attempted gapping in prelim test: 9239
Number of HSP's gapped (non-prelim): 502
length of query: 2093
length of database: 18,247,518
effective HSP length: 118
effective length of query: 1975
effective length of database: 13,779,330
effective search space: 27214176750
effective search space used: 27214176750
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 70 (31.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.