Guide to the Human Genome
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Search of human proteins with 164420681

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|164420681 methionyl aminopeptidase 1 [Homo sapiens]
         (386 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|164420681 methionyl aminopeptidase 1 [Homo sapiens]                814   0.0  
gi|40385867 methionine aminopeptidase 1D [Homo sapiens]               254   9e-68
gi|124494254 ErbB3-binding protein 1 [Homo sapiens]                    41   0.002
gi|28461129 ankyrin repeat and MYND domain containing 2 [Homo sa...    34   0.25 
gi|254028267 myosin 1H [Homo sapiens]                                  33   0.57 
gi|11559925 X-prolyl aminopeptidase (aminopeptidase P) 3, putati...    33   0.57 
gi|38505161 tudor domain containing 1 [Homo sapiens]                   32   1.3  
gi|134142345 ATP-binding cassette, sub-family C, member 1 isofor...    30   3.7  
gi|134142342 ATP-binding cassette, sub-family C, member 1 isofor...    30   3.7  
gi|134142340 ATP-binding cassette, sub-family C, member 1 isofor...    30   3.7  
gi|134142335 ATP-binding cassette, sub-family C, member 1 isofor...    30   3.7  
gi|134142337 ATP-binding cassette, sub-family C, member 1 isofor...    30   3.7  
gi|37594444 zinc finger, MYND domain-containing 10 [Homo sapiens]      30   3.7  
gi|4557733 latent transforming growth factor beta binding protei...    30   4.8  
gi|20149698 l(3)mbt-like 2 [Homo sapiens]                              29   6.3  
gi|13377002 crystallin, gamma D [Homo sapiens]                         29   8.2  
gi|191252814 RIMS binding protein 3B [Homo sapiens]                    29   8.2  
gi|191252806 RIMS binding protein 3C [Homo sapiens]                    29   8.2  
gi|20149643 zinc finger, HIT type 6 [Homo sapiens]                     29   8.2  

>gi|164420681 methionyl aminopeptidase 1 [Homo sapiens]
          Length = 386

 Score =  814 bits (2103), Expect = 0.0
 Identities = 386/386 (100%), Positives = 386/386 (100%)

Query: 1   MAAVETRVCETDGCSSEAKLQCPTCIKLGIQGSYFCSQECFKGSWATHKLLHKKAKDEKA 60
           MAAVETRVCETDGCSSEAKLQCPTCIKLGIQGSYFCSQECFKGSWATHKLLHKKAKDEKA
Sbjct: 1   MAAVETRVCETDGCSSEAKLQCPTCIKLGIQGSYFCSQECFKGSWATHKLLHKKAKDEKA 60

Query: 61  KREVSSWTVEGDINTDPWAGYRYTGKLRPHYPLMPTRPVPSYIQRPDYADHPLGMSESEQ 120
           KREVSSWTVEGDINTDPWAGYRYTGKLRPHYPLMPTRPVPSYIQRPDYADHPLGMSESEQ
Sbjct: 61  KREVSSWTVEGDINTDPWAGYRYTGKLRPHYPLMPTRPVPSYIQRPDYADHPLGMSESEQ 120

Query: 121 ALKGTSQIKLLSSEDIEGMRLVCRLAREVLDVAAGMIKPGVTTEEIDHAVHLACIARNCY 180
           ALKGTSQIKLLSSEDIEGMRLVCRLAREVLDVAAGMIKPGVTTEEIDHAVHLACIARNCY
Sbjct: 121 ALKGTSQIKLLSSEDIEGMRLVCRLAREVLDVAAGMIKPGVTTEEIDHAVHLACIARNCY 180

Query: 181 PSPLNYYNFPKSCCTSVNEVICHGIPDRRPLQEGDIVNVDITLYRNGYHGDLNETFFVGE 240
           PSPLNYYNFPKSCCTSVNEVICHGIPDRRPLQEGDIVNVDITLYRNGYHGDLNETFFVGE
Sbjct: 181 PSPLNYYNFPKSCCTSVNEVICHGIPDRRPLQEGDIVNVDITLYRNGYHGDLNETFFVGE 240

Query: 241 VDDGARKLVQTTYECLMQAIDAVKPGVRYRELGNIIQKHAQANGFSVVRSYCGHGIHKLF 300
           VDDGARKLVQTTYECLMQAIDAVKPGVRYRELGNIIQKHAQANGFSVVRSYCGHGIHKLF
Sbjct: 241 VDDGARKLVQTTYECLMQAIDAVKPGVRYRELGNIIQKHAQANGFSVVRSYCGHGIHKLF 300

Query: 301 HTAPNVPHYAKNKAVGVMKSGHVFTIEPMICEGGWQDETWPDGWTAVTRDGKRSAQFEHT 360
           HTAPNVPHYAKNKAVGVMKSGHVFTIEPMICEGGWQDETWPDGWTAVTRDGKRSAQFEHT
Sbjct: 301 HTAPNVPHYAKNKAVGVMKSGHVFTIEPMICEGGWQDETWPDGWTAVTRDGKRSAQFEHT 360

Query: 361 LLVTDTGCEILTRRLDSARPHFMSQF 386
           LLVTDTGCEILTRRLDSARPHFMSQF
Sbjct: 361 LLVTDTGCEILTRRLDSARPHFMSQF 386


>gi|40385867 methionine aminopeptidase 1D [Homo sapiens]
          Length = 335

 Score =  254 bits (649), Expect = 9e-68
 Identities = 127/276 (46%), Positives = 172/276 (62%), Gaps = 8/276 (2%)

Query: 98  PVPSYIQRPDYADHPLGMSESEQALKGTSQIKLLSSEDIEGMRLVCRLAREVLDVAAGMI 157
           PVP +I++PDY    +     +        I++ + + I+G+   C+LAR VL +A   +
Sbjct: 63  PVPKHIKKPDYVTTGIVPDWGDS-------IEVKNEDQIQGLHQACQLARHVLLLAGKSL 115

Query: 158 KPGVTTEEIDHAVHLACIARNCYPSPLNYYNFPKSCCTSVNEVICHGIPDRRPLQEGDIV 217
           K  +TTEEID  VH   I+ N YPSPL Y  FPKS CTSVN V+CHGIPD RPLQ+GDI+
Sbjct: 116 KVDMTTEEIDALVHREIISHNAYPSPLGYGGFPKSVCTSVNNVLCHGIPDSRPLQDGDII 175

Query: 218 NVDITLYRNGYHGDLNETFFVGEVDDGARKLVQTTYECLMQAIDAVKPGVRYRELGNIIQ 277
           N+D+T+Y NGYHGD +ETF VG VD+  +KLV+    C  +AI A + G  +  +GN I 
Sbjct: 176 NIDVTVYYNGYHGDTSETFLVGNVDECGKKLVEVARRCRDEAIAACRAGAPFSVIGNTIS 235

Query: 278 KHAQANGFSVVRSYCGHGIHKLFHTAPNVPHYAKNKAVGVMKSGHVFTIEPMICEGGWQD 337
                NGF V   + GHGI   FH  P + H+A +  +  M+ G  FTIEP+I EG  + 
Sbjct: 236 HITHQNGFQVCPHFVGHGIGSYFHGHPEIWHHANDSDL-PMEEGMAFTIEPIITEGSPEF 294

Query: 338 ETWPDGWTAVTRDGKRSAQFEHTLLVTDTGCEILTR 373
           +   D WT V+ D +RSAQFEHT+L+T  G +ILT+
Sbjct: 295 KVLEDAWTVVSLDNQRSAQFEHTVLITSRGAQILTK 330


>gi|124494254 ErbB3-binding protein 1 [Homo sapiens]
          Length = 394

 Score = 40.8 bits (94), Expect = 0.002
 Identities = 29/115 (25%), Positives = 53/115 (46%), Gaps = 11/115 (9%)

Query: 189 FPKSCCTSVNEVICHGIPDRRP----LQEGDIVNVDITLYRNGYHGDLNETFFVG----- 239
           FP S   SVN  +CH  P +      L+EGD+V +D+ ++ +G+  ++  TF V      
Sbjct: 76  FPTSI--SVNNCVCHFSPLKSDQDYILKEGDLVKIDLGVHVDGFIANVAHTFVVDVAQGT 133

Query: 240 EVDDGARKLVQTTYECLMQAIDAVKPGVRYRELGNIIQKHAQANGFSVVRSYCGH 294
           +V      +++  + C   A+  VKPG +  ++     K A +   + +     H
Sbjct: 134 QVTGRKADVIKAAHLCAEAALRLVKPGNQNTQVTEAWNKVAHSFNCTPIEGMLSH 188


>gi|28461129 ankyrin repeat and MYND domain containing 2 [Homo
           sapiens]
          Length = 441

 Score = 33.9 bits (76), Expect = 0.25
 Identities = 21/63 (33%), Positives = 31/63 (49%), Gaps = 6/63 (9%)

Query: 4   VETRVCETDGCSSEAKLQCPTCIKLGIQGSYFCSQECFKGSWATHKLLHKKAKDEKAKRE 63
           V+   C T G    +K +C  C K+ I    +C Q C K  W THK + K  KD   K++
Sbjct: 315 VDVEFCTTCGEKGASK-RCSVC-KMVI----YCDQTCQKTHWFTHKKICKNLKDIYEKQQ 368

Query: 64  VSS 66
           + +
Sbjct: 369 LEA 371


>gi|254028267 myosin 1H [Homo sapiens]
          Length = 1022

 Score = 32.7 bits (73), Expect = 0.57
 Identities = 39/156 (25%), Positives = 65/156 (41%), Gaps = 26/156 (16%)

Query: 191 KSCCTSVNEVICHGIP-DRRPLQEGDIVNVDITLYR-NGYHGDLNETFFVGEVDDG---A 245
           K C  ++ +  C GI  +R+ + +  +V  +I   R +GY   LN+ F    +D+G    
Sbjct: 809 KMCVRNLVQKYCRGITAERKAMMQQKVVTSEIFRGRKDGYTESLNQPFVNSRIDEGDINP 868

Query: 246 RKLVQTTYECLMQAIDAVK---PGVRYR--------------ELGNIIQKHAQANGFSVV 288
           + L   ++E +   +  +K    G + R              EL  I QK   +    V 
Sbjct: 869 KVLQLISHEKIQYGVPVIKYDRKGFKARQRQLILTQKAAYVVELAKIKQKIEYSALKGVS 928

Query: 289 RSYCGHGIHKLFHTAPNVPHYAKNKAVGVMKSGHVF 324
            S    GI  + H +   P  +K K   V++ GHVF
Sbjct: 929 TSNLSDGI-LVIHVS---PEDSKQKGDAVLQCGHVF 960


>gi|11559925 X-prolyl aminopeptidase (aminopeptidase P) 3, putative
           [Homo sapiens]
          Length = 507

 Score = 32.7 bits (73), Expect = 0.57
 Identities = 52/258 (20%), Positives = 94/258 (36%), Gaps = 39/258 (15%)

Query: 100 PSYIQRPDYADHPL--GMSESEQALKGTSQI-----KLLSSEDIEGMRLVCRLAREVLDV 152
           PS+ Q       PL    ++S+  ++G  Q+      + S  +IE M++  +L  +    
Sbjct: 209 PSHAQLHSDYMQPLTEAKAKSKNKVRGVQQLIQRLRLIKSPAEIERMQIAGKLTSQAFIE 268

Query: 153 AAGMIKPGVTTEEIDHAVHLACIARNCYPSPLNYYNFPKSCCTSVNEVICHGIPDRRPLQ 212
                K  V    +       C AR       +   +P            H + + + ++
Sbjct: 269 TMFTSKAPVEEAFLYAKFEFECRARGA-----DILAYPPVVAGGNRSNTLHYVKNNQLIK 323

Query: 213 EGDIVNVDITLYRNGYHGDLNETFFV-GEVDDGARKLVQTTYECLMQAIDAVKPGV---- 267
           +G++V +D     + Y  D+  T+ V G       +L +   E     +    PG     
Sbjct: 324 DGEMVLLDGGCESSCYVSDITRTWPVNGRFTAPQAELYEAVLEIQRDCLALCFPGTSLEN 383

Query: 268 -----------RYRELGNIIQKHAQANGFSVVRSYC----GHGIHKLFHTAPNVPHYAKN 312
                      + ++LG I++   + N F   R YC    GH +    H  P++P     
Sbjct: 384 IYSMMLTLIGQKLKDLG-IMKNIKENNAFKAARKYCPHHVGHYLGMDVHDTPDMPRSLP- 441

Query: 313 KAVGVMKSGHVFTIEPMI 330
                ++ G V TIEP I
Sbjct: 442 -----LQPGMVITIEPGI 454


>gi|38505161 tudor domain containing 1 [Homo sapiens]
          Length = 1189

 Score = 31.6 bits (70), Expect = 1.3
 Identities = 31/147 (21%), Positives = 57/147 (38%), Gaps = 28/147 (19%)

Query: 20  LQCPTCIKLGIQGS---------YFCSQECFKGSWATHKLLHKKAKDEKAKREVSSWTVE 70
           L+  TC + G+ GS         Y+CS  C +  W+ H ++ +  +    K E  S    
Sbjct: 165 LRSTTCHRCGLFGSLRCSQCKQTYYCSTACQRRDWSAHSIVCRPVQPNFHKLENKSSIET 224

Query: 71  GDINTDPWAGYRYTGKLRPHYPLMPTRPVPSYIQRPDYADHPLGMSESEQALKGT----- 125
            D+  +           +   PL  T+ +  + +R  ++D      +    +KGT     
Sbjct: 225 KDVEVNN----------KSDCPLGVTKEIAIWAERIMFSDLRSLQLKKTMEIKGTVTEFK 274

Query: 126 ----SQIKLLSSEDIEGMRLVCRLARE 148
                 ++L SSE +E M  +    +E
Sbjct: 275 HPGDFYVQLYSSEVLEYMNQLSASLKE 301


>gi|134142345 ATP-binding cassette, sub-family C, member 1 isoform 3
           [Homo sapiens]
          Length = 1475

 Score = 30.0 bits (66), Expect = 3.7
 Identities = 15/37 (40%), Positives = 24/37 (64%)

Query: 342 DGWTAVTRDGKRSAQFEHTLLVTDTGCEILTRRLDSA 378
           +G T V+  GK + Q E+ +LVTD+  + L R+L S+
Sbjct: 825 NGVTGVSGPGKEAKQMENGMLVTDSAGKQLQRQLSSS 861


>gi|134142342 ATP-binding cassette, sub-family C, member 1 isoform 4
           [Homo sapiens]
          Length = 1416

 Score = 30.0 bits (66), Expect = 3.7
 Identities = 15/37 (40%), Positives = 24/37 (64%)

Query: 342 DGWTAVTRDGKRSAQFEHTLLVTDTGCEILTRRLDSA 378
           +G T V+  GK + Q E+ +LVTD+  + L R+L S+
Sbjct: 766 NGVTGVSGPGKEAKQMENGMLVTDSAGKQLQRQLSSS 802


>gi|134142340 ATP-binding cassette, sub-family C, member 1 isoform 2
           [Homo sapiens]
          Length = 1472

 Score = 30.0 bits (66), Expect = 3.7
 Identities = 15/37 (40%), Positives = 24/37 (64%)

Query: 342 DGWTAVTRDGKRSAQFEHTLLVTDTGCEILTRRLDSA 378
           +G T V+  GK + Q E+ +LVTD+  + L R+L S+
Sbjct: 822 NGVTGVSGPGKEAKQMENGMLVTDSAGKQLQRQLSSS 858


>gi|134142335 ATP-binding cassette, sub-family C, member 1 isoform 5
           [Homo sapiens]
          Length = 1466

 Score = 30.0 bits (66), Expect = 3.7
 Identities = 15/37 (40%), Positives = 24/37 (64%)

Query: 342 DGWTAVTRDGKRSAQFEHTLLVTDTGCEILTRRLDSA 378
           +G T V+  GK + Q E+ +LVTD+  + L R+L S+
Sbjct: 881 NGVTGVSGPGKEAKQMENGMLVTDSAGKQLQRQLSSS 917


>gi|134142337 ATP-binding cassette, sub-family C, member 1 isoform 1
           [Homo sapiens]
          Length = 1531

 Score = 30.0 bits (66), Expect = 3.7
 Identities = 15/37 (40%), Positives = 24/37 (64%)

Query: 342 DGWTAVTRDGKRSAQFEHTLLVTDTGCEILTRRLDSA 378
           +G T V+  GK + Q E+ +LVTD+  + L R+L S+
Sbjct: 881 NGVTGVSGPGKEAKQMENGMLVTDSAGKQLQRQLSSS 917


>gi|37594444 zinc finger, MYND domain-containing 10 [Homo sapiens]
          Length = 440

 Score = 30.0 bits (66), Expect = 3.7
 Identities = 16/49 (32%), Positives = 24/49 (48%), Gaps = 6/49 (12%)

Query: 14  CSSEAKLQCPTCIKLGIQGSYFCSQECFKGSWATH-KLLHKKAKDEKAK 61
           CS+EA  +C  C     Q  ++C +EC    W  H K     A+ ++AK
Sbjct: 397 CSAEASKRCSRC-----QNEWYCCRECQVKHWEKHGKTCVLAAQGDRAK 440


>gi|4557733 latent transforming growth factor beta binding protein 2
            [Homo sapiens]
          Length = 1821

 Score = 29.6 bits (65), Expect = 4.8
 Identities = 15/36 (41%), Positives = 20/36 (55%), Gaps = 3/36 (8%)

Query: 10   ETDGCSSEAKLQCPTCIKLGIQGSYFCSQECFKGSW 45
            + D C+S A   CPT + L  +GS+ CS  C  G W
Sbjct: 1051 DVDECASRAS--CPTGLCLNTEGSFACS-ACENGYW 1083


>gi|20149698 l(3)mbt-like 2 [Homo sapiens]
          Length = 705

 Score = 29.3 bits (64), Expect = 6.3
 Identities = 21/70 (30%), Positives = 30/70 (42%), Gaps = 13/70 (18%)

Query: 85  GKLRPHYPLMPTRPVPSYIQRPDYADHPLGMSESEQALKGTSQIKLLSSEDIEGMRLVCR 144
           GK R   P   TRP+    ++P   D P G              + +SSE + G  +  R
Sbjct: 627 GKKRKRIPPTKTRPLRQGSKKPLLEDDPQG-------------ARKISSEPVPGEIIAVR 673

Query: 145 LAREVLDVAA 154
           +  E LDVA+
Sbjct: 674 VKEEHLDVAS 683


>gi|13377002 crystallin, gamma D [Homo sapiens]
          Length = 174

 Score = 28.9 bits (63), Expect = 8.2
 Identities = 15/47 (31%), Positives = 28/47 (59%), Gaps = 7/47 (14%)

Query: 102 YIQRPDYADHP--LGMSESEQALK-----GTSQIKLLSSEDIEGMRL 141
           +++R DYADH   +G+S+S ++ +     G+ +I+L   ED  G  +
Sbjct: 57  FLRRGDYADHQQWMGLSDSVRSCRLIPHSGSHRIRLYEREDYRGQMI 103


>gi|191252814 RIMS binding protein 3B [Homo sapiens]
          Length = 1639

 Score = 28.9 bits (63), Expect = 8.2
 Identities = 20/58 (34%), Positives = 30/58 (51%), Gaps = 12/58 (20%)

Query: 210 PLQEGDIVNVDITLYRNGYHGDLNET-FFVGEVDDGARKLVQTTYECLMQAIDAVKPG 266
           PL  GD + +          GD++E  F+ GE+DDG R LV + +  + Q  D+  PG
Sbjct: 858 PLTAGDYIYI---------FGDMDEDGFYEGELDDGRRGLVPSNF--VEQIPDSYIPG 904


>gi|191252806 RIMS binding protein 3C [Homo sapiens]
          Length = 1639

 Score = 28.9 bits (63), Expect = 8.2
 Identities = 20/58 (34%), Positives = 30/58 (51%), Gaps = 12/58 (20%)

Query: 210 PLQEGDIVNVDITLYRNGYHGDLNET-FFVGEVDDGARKLVQTTYECLMQAIDAVKPG 266
           PL  GD + +          GD++E  F+ GE+DDG R LV + +  + Q  D+  PG
Sbjct: 858 PLTAGDYIYI---------FGDMDEDGFYEGELDDGRRGLVPSNF--VEQIPDSYIPG 904


>gi|20149643 zinc finger, HIT type 6 [Homo sapiens]
          Length = 470

 Score = 28.9 bits (63), Expect = 8.2
 Identities = 15/34 (44%), Positives = 19/34 (55%), Gaps = 7/34 (20%)

Query: 9   CETDGCSSEAKLQCPTCIKLGIQGSYFCSQECFK 42
           CET G + EAK +CP C++      Y CS  C K
Sbjct: 220 CETCG-TEEAKYRCPRCMR------YSCSLPCVK 246


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.136    0.432 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,900,968
Number of Sequences: 37866
Number of extensions: 745821
Number of successful extensions: 1609
Number of sequences better than 10.0: 19
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 1595
Number of HSP's gapped (non-prelim): 22
length of query: 386
length of database: 18,247,518
effective HSP length: 104
effective length of query: 282
effective length of database: 14,309,454
effective search space: 4035266028
effective search space used: 4035266028
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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