Guide to the Human Genome
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Search of human proteins with 16306595

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|16306595 S-phase kinase-associated protein 2 isoform 1 [Homo
sapiens]
         (424 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|16306595 S-phase kinase-associated protein 2 isoform 1 [Homo ...   859   0.0  
gi|14249170 S-phase kinase-associated protein 2 isoform 2 [Homo ...   716   0.0  
gi|27734755 F-box and leucine-rich repeat protein 20 [Homo sapiens]    81   2e-15
gi|16306582 F-box and leucine-rich repeat protein 2 [Homo sapiens]     80   3e-15
gi|6912466 F-box and leucine-rich repeat protein 7 [Homo sapiens]      75   1e-13
gi|54112382 F-box and leucine-rich repeat protein 10 isoform a [...    58   1e-08
gi|54112380 F-box and leucine-rich repeat protein 10 isoform b [...    57   2e-08
gi|16306588 F-box and leucine-rich repeat protein 4 [Homo sapiens]     57   3e-08
gi|161333854 F-box and leucine-rich repeat protein 13 isoform 2 ...    55   1e-07
gi|161333852 F-box and leucine-rich repeat protein 13 isoform 1 ...    55   1e-07
gi|16306580 F-box and leucine-rich repeat protein 11 [Homo sapiens]    53   5e-07
gi|8923179 F-box and leucine-rich repeat protein 12 [Homo sapiens]     52   8e-07
gi|16306576 F-box and leucine-rich repeat protein 6 isoform 1 [H...    51   2e-06
gi|190194416 F-box and leucine-rich repeat protein 15 [Homo sapi...    50   5e-06
gi|148922963 F-box and leucine-rich repeat protein 21 [Homo sapi...    49   7e-06
gi|157168349 F-box and leucine-rich repeat protein 19 [Homo sapi...    48   2e-05
gi|61742136 F-box and leucine-rich repeat protein 6 isoform 2 [H...    47   4e-05
gi|24025682 F-box and leucine-rich repeat protein 16 [Homo sapiens]    45   1e-04
gi|22748931 F-box and leucine-rich repeat protein 14 [Homo sapiens]    45   1e-04
gi|51873034 F-box and leucine-rich repeat protein 9 [Homo sapiens]     45   2e-04
gi|16306591 F-box and leucine-rich repeat protein 9 [Homo sapiens]     45   2e-04
gi|30089926 F-box only protein 11 isoform 1 [Homo sapiens]             44   4e-04
gi|30089924 F-box only protein 11 isoform 2 [Homo sapiens]             44   4e-04
gi|30089922 F-box only protein 11 isoform 3 [Homo sapiens]             44   4e-04
gi|164663798 antagonist of mitotic exit network 1 homolog [Homo ...    41   0.002
gi|229576894 F-box and WD repeat domain containing 12 isoform 2 ...    39   0.007
gi|229576873 F-box and WD repeat domain containing 12 isoform 1 ...    39   0.007
gi|219281831 F-box protein 15 isoform 2 [Homo sapiens]                 37   0.034
gi|16306574 F-box and leucine-rich repeat protein 5 isoform 2 [H...    37   0.034
gi|16306572 F-box and leucine-rich repeat protein 5 isoform 1 [H...    37   0.034

>gi|16306595 S-phase kinase-associated protein 2 isoform 1 [Homo
           sapiens]
          Length = 424

 Score =  859 bits (2220), Expect = 0.0
 Identities = 424/424 (100%), Positives = 424/424 (100%)

Query: 1   MHRKHLQEIPDLSSNVATSFTWGWDSSKTSELLSGMGVSALEKEEPDSENIPQELLSNLG 60
           MHRKHLQEIPDLSSNVATSFTWGWDSSKTSELLSGMGVSALEKEEPDSENIPQELLSNLG
Sbjct: 1   MHRKHLQEIPDLSSNVATSFTWGWDSSKTSELLSGMGVSALEKEEPDSENIPQELLSNLG 60

Query: 61  HPESPPRKRLKSKGSDKDFVIVRRPKLNRENFPGVSWDSLPDELLLGIFSCLCLPELLKV 120
           HPESPPRKRLKSKGSDKDFVIVRRPKLNRENFPGVSWDSLPDELLLGIFSCLCLPELLKV
Sbjct: 61  HPESPPRKRLKSKGSDKDFVIVRRPKLNRENFPGVSWDSLPDELLLGIFSCLCLPELLKV 120

Query: 121 SGVCKRWYRLASDESLWQTLDLTGKNLHPDVTGRLLSQGVIAFRCPRSFMDQPLAEHFSP 180
           SGVCKRWYRLASDESLWQTLDLTGKNLHPDVTGRLLSQGVIAFRCPRSFMDQPLAEHFSP
Sbjct: 121 SGVCKRWYRLASDESLWQTLDLTGKNLHPDVTGRLLSQGVIAFRCPRSFMDQPLAEHFSP 180

Query: 181 FRVQHMDLSNSVIEVSTLHGILSQCSKLQNLSLEGLRLSDPIVNTLAKNSNLVRLNLSGC 240
           FRVQHMDLSNSVIEVSTLHGILSQCSKLQNLSLEGLRLSDPIVNTLAKNSNLVRLNLSGC
Sbjct: 181 FRVQHMDLSNSVIEVSTLHGILSQCSKLQNLSLEGLRLSDPIVNTLAKNSNLVRLNLSGC 240

Query: 241 SGFSEFALQTLLSSCSRLDELNLSWCFDFTEKHVQVAVAHVSETITQLNLSGYRKNLQKS 300
           SGFSEFALQTLLSSCSRLDELNLSWCFDFTEKHVQVAVAHVSETITQLNLSGYRKNLQKS
Sbjct: 241 SGFSEFALQTLLSSCSRLDELNLSWCFDFTEKHVQVAVAHVSETITQLNLSGYRKNLQKS 300

Query: 301 DLSTLVRRCPNLVHLDLSDSVMLKNDCFQEFFQLNYLQHLSLSRCYDIIPETLLELGEIP 360
           DLSTLVRRCPNLVHLDLSDSVMLKNDCFQEFFQLNYLQHLSLSRCYDIIPETLLELGEIP
Sbjct: 301 DLSTLVRRCPNLVHLDLSDSVMLKNDCFQEFFQLNYLQHLSLSRCYDIIPETLLELGEIP 360

Query: 361 TLKTLQVFGIVPDGTLQLLKEALPHLQINCSHFTTIARPTIGNKKNQEIWGIKCRLTLQK 420
           TLKTLQVFGIVPDGTLQLLKEALPHLQINCSHFTTIARPTIGNKKNQEIWGIKCRLTLQK
Sbjct: 361 TLKTLQVFGIVPDGTLQLLKEALPHLQINCSHFTTIARPTIGNKKNQEIWGIKCRLTLQK 420

Query: 421 PSCL 424
           PSCL
Sbjct: 421 PSCL 424


>gi|14249170 S-phase kinase-associated protein 2 isoform 2 [Homo
           sapiens]
          Length = 410

 Score =  716 bits (1849), Expect = 0.0
 Identities = 354/354 (100%), Positives = 354/354 (100%)

Query: 1   MHRKHLQEIPDLSSNVATSFTWGWDSSKTSELLSGMGVSALEKEEPDSENIPQELLSNLG 60
           MHRKHLQEIPDLSSNVATSFTWGWDSSKTSELLSGMGVSALEKEEPDSENIPQELLSNLG
Sbjct: 1   MHRKHLQEIPDLSSNVATSFTWGWDSSKTSELLSGMGVSALEKEEPDSENIPQELLSNLG 60

Query: 61  HPESPPRKRLKSKGSDKDFVIVRRPKLNRENFPGVSWDSLPDELLLGIFSCLCLPELLKV 120
           HPESPPRKRLKSKGSDKDFVIVRRPKLNRENFPGVSWDSLPDELLLGIFSCLCLPELLKV
Sbjct: 61  HPESPPRKRLKSKGSDKDFVIVRRPKLNRENFPGVSWDSLPDELLLGIFSCLCLPELLKV 120

Query: 121 SGVCKRWYRLASDESLWQTLDLTGKNLHPDVTGRLLSQGVIAFRCPRSFMDQPLAEHFSP 180
           SGVCKRWYRLASDESLWQTLDLTGKNLHPDVTGRLLSQGVIAFRCPRSFMDQPLAEHFSP
Sbjct: 121 SGVCKRWYRLASDESLWQTLDLTGKNLHPDVTGRLLSQGVIAFRCPRSFMDQPLAEHFSP 180

Query: 181 FRVQHMDLSNSVIEVSTLHGILSQCSKLQNLSLEGLRLSDPIVNTLAKNSNLVRLNLSGC 240
           FRVQHMDLSNSVIEVSTLHGILSQCSKLQNLSLEGLRLSDPIVNTLAKNSNLVRLNLSGC
Sbjct: 181 FRVQHMDLSNSVIEVSTLHGILSQCSKLQNLSLEGLRLSDPIVNTLAKNSNLVRLNLSGC 240

Query: 241 SGFSEFALQTLLSSCSRLDELNLSWCFDFTEKHVQVAVAHVSETITQLNLSGYRKNLQKS 300
           SGFSEFALQTLLSSCSRLDELNLSWCFDFTEKHVQVAVAHVSETITQLNLSGYRKNLQKS
Sbjct: 241 SGFSEFALQTLLSSCSRLDELNLSWCFDFTEKHVQVAVAHVSETITQLNLSGYRKNLQKS 300

Query: 301 DLSTLVRRCPNLVHLDLSDSVMLKNDCFQEFFQLNYLQHLSLSRCYDIIPETLL 354
           DLSTLVRRCPNLVHLDLSDSVMLKNDCFQEFFQLNYLQHLSLSRCYDIIPETLL
Sbjct: 301 DLSTLVRRCPNLVHLDLSDSVMLKNDCFQEFFQLNYLQHLSLSRCYDIIPETLL 354


>gi|27734755 F-box and leucine-rich repeat protein 20 [Homo sapiens]
          Length = 436

 Score = 80.9 bits (198), Expect = 2e-15
 Identities = 77/272 (28%), Positives = 123/272 (45%), Gaps = 23/272 (8%)

Query: 100 LPDELLLGIFSCLCLPELLKVSGVCKRWYRLASDESLWQTLDLTGKNLHPDVTGRLLSQG 159
           LP ELLL IFS L +  L + + V + W  LA D S WQ +DL   +   D+ GR++   
Sbjct: 28  LPKELLLRIFSFLDVVTLCRCAQVSRAWNVLALDGSNWQRIDLF--DFQRDIEGRVVEN- 84

Query: 160 VIAFRCPRSFMDQPLAEHFSPFRVQHMDLSNSVIEVSTLHGILSQCSKLQNLSLEG-LRL 218
            I+ RC        L                  +  + L      C  ++ L+L G  + 
Sbjct: 85  -ISKRCGGFLRKLSLRGCLG-------------VGDNALRTFAQNCRNIEVLNLNGCTKT 130

Query: 219 SDPIVNTLAK-NSNLVRLNLSGCSGFSEFALQTLLSSCSRLDELNLSWCFDFTEKHVQVA 277
           +D    +L+K  S L  L+L+ C+  +  +L+ L   C  L++LN+SWC   T+  +Q A
Sbjct: 131 TDATCTSLSKFCSKLRHLDLASCTSITNMSLKALSEGCPLLEQLNISWCDQVTKDGIQ-A 189

Query: 278 VAHVSETITQLNLSGYRKNLQKSDLSTLVRRCPNLVHLDLSDSVMLKNDCFQEFFQ-LNY 336
           +      +  L L G  + L+   L  +   CP LV L+L   + + ++      +  + 
Sbjct: 190 LVRGCGGLKALFLKGCTQ-LEDEALKYIGAHCPELVTLNLQTCLQITDEGLITICRGCHK 248

Query: 337 LQHLSLSRCYDIIPETLLELGE-IPTLKTLQV 367
           LQ L  S C +I    L  LG+  P L+ L+V
Sbjct: 249 LQSLCASGCSNITDAILNALGQNCPRLRILEV 280



 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 50/226 (22%), Positives = 103/226 (45%), Gaps = 16/226 (7%)

Query: 193 IEVSTLHGILSQCSKLQNLSLEG-LRLSDPIVNTLAKNSN-LVRLNLSGCSGFSEFALQT 250
           +E   L  I + C +L  L+L+  L+++D  + T+ +  + L  L  SGCS  ++  L  
Sbjct: 208 LEDEALKYIGAHCPELVTLNLQTCLQITDEGLITICRGCHKLQSLCASGCSNITDAILNA 267

Query: 251 LLSSCSRLDELNLSWCFDFTEKHVQVAVAHVSETITQLNLSGYRKNLQKSDLSTLVR--- 307
           L  +C RL  L ++ C   T+    V    ++    +L      + +Q +D STL++   
Sbjct: 268 LGQNCPRLRILEVARCSQLTD----VGFTTLARNCHELEKMDLEECVQITD-STLIQLSI 322

Query: 308 RCPNLVHLDLSDSVMLKNDCFQEF----FQLNYLQHLSLSRCYDIIPETLLELGEIPTLK 363
            CP L  L LS   ++ +D  +         + L+ + L  C  I   +L  L    +L+
Sbjct: 323 HCPRLQVLSLSHCELITDDGIRHLGNGACAHDQLEVIELDNCPLITDASLEHLKSCHSLE 382

Query: 364 TLQVFGI--VPDGTLQLLKEALPHLQINCSHFTTIARPTIGNKKNQ 407
            ++++    +    ++ L+  LP+++++         P++G  + +
Sbjct: 383 RIELYDCQQITRAGIKRLRTHLPNIKVHAYFAPVTPPPSVGGSRQR 428


>gi|16306582 F-box and leucine-rich repeat protein 2 [Homo sapiens]
          Length = 423

 Score = 80.5 bits (197), Expect = 3e-15
 Identities = 78/281 (27%), Positives = 130/281 (46%), Gaps = 25/281 (8%)

Query: 91  NFPGVSWDSLPDELLLGIFSCLCLPELLKVSGVCKRWYRLASDESLWQTLDLTGKNLHPD 150
           N  G+    LP ELLL IFS L +  L + + + K W  LA D S WQ +DL   N   D
Sbjct: 6   NDEGLINKKLPKELLLRIFSFLDIVTLCRCAQISKAWNILALDGSNWQRIDLF--NFQID 63

Query: 151 VTGRLLSQGVIAFRCPRSFMDQPLAEHFSPFRVQHMDLSNSV-IEVSTLHGILSQCSKLQ 209
           V GR++    I+ RC                 ++ + L   + +  S+L      C  ++
Sbjct: 64  VEGRVVEN--ISKRCGGF--------------LRKLSLRGCIGVGDSSLKTFAQNCRNIE 107

Query: 210 NLSLEG-LRLSDPIVNTLAK-NSNLVRLNLSGCSGFSEFALQTLLSSCSRLDELNLSWCF 267
           +L+L G  +++D    +L++  S L  L+L+ C   +  +L+ +   C  L+ LNLSWC 
Sbjct: 108 HLNLNGCTKITDSTCYSLSRFCSKLKHLDLTSCVSITNSSLKGISEGCRNLEYLNLSWCD 167

Query: 268 DFTEKHVQVAVAHVSETITQLNLSGYRKNLQKSDLSTLVRRCPNLVHLDLSDSVMLKNDC 327
             T+  ++ A+      +  L L G  + L+   L  +   C  LV L+L     + ++ 
Sbjct: 168 QITKDGIE-ALVRGCRGLKALLLRGCTQ-LEDEALKHIQNYCHELVSLNLQSCSRITDEG 225

Query: 328 FQEFFQ-LNYLQHLSLSRCYDIIPETLLELG-EIPTLKTLQ 366
             +  +  + LQ L LS C ++   +L  LG   P L+ L+
Sbjct: 226 VVQICRGCHRLQALCLSGCSNLTDASLTALGLNCPRLQILE 266



 Score = 48.9 bits (115), Expect = 9e-06
 Identities = 44/178 (24%), Positives = 75/178 (42%), Gaps = 35/178 (19%)

Query: 222 IVNTLAKNSN--LVRLNLSGCSGFSEFALQTLLSSCSRLDELNLSWCFDFTEKHVQVAVA 279
           +V  ++K     L +L+L GC G  + +L+T   +C  ++ LNL+ C   T+        
Sbjct: 68  VVENISKRCGGFLRKLSLRGCIGVGDSSLKTFAQNCRNIEHLNLNGCTKITD-------- 119

Query: 280 HVSETITQLNLSGYRKNLQKSDLSTLVRRCPNLVHLDLSDSVMLKNDCFQEFFQ-LNYLQ 338
                               S   +L R C  L HLDL+  V + N   +   +    L+
Sbjct: 120 --------------------STCYSLSRFCSKLKHLDLTSCVSITNSSLKGISEGCRNLE 159

Query: 339 HLSLSRCYDIIPETLLELGEIPTLKTLQVFGIVPDGTLQLLKEALPHLQINCSHFTTI 396
           +L+LS C  I  + +  L  +   + L+   ++  G  QL  EAL H+Q  C    ++
Sbjct: 160 YLNLSWCDQITKDGIEAL--VRGCRGLKA--LLLRGCTQLEDEALKHIQNYCHELVSL 213



 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 56/227 (24%), Positives = 97/227 (42%), Gaps = 33/227 (14%)

Query: 193 IEVSTLHGILSQCSKLQNLSLEGL-RLSDPIVNTLAKNSN-LVRLNLSGCSGFSEFALQT 250
           +E   L  I + C +L +L+L+   R++D  V  + +  + L  L LSGCS  ++ +L  
Sbjct: 195 LEDEALKHIQNYCHELVSLNLQSCSRITDEGVVQICRGCHRLQALCLSGCSNLTDASLTA 254

Query: 251 LLSSCSRLDELNLSWCFDFTEKHVQVAVAHVSETITQLNLSGYRKNLQKSDL-------- 302
           L  +C RL  L  + C   T+    +   +  E             L+K DL        
Sbjct: 255 LGLNCPRLQILEAARCSHLTDAGFTLLARNCHE-------------LEKMDLEECILITD 301

Query: 303 STLVR---RCPNLVHLDLSDSVMLKNDCFQEFFQL----NYLQHLSLSRCYDIIPETLLE 355
           STL++    CP L  L LS   ++ +D              L+ L L  C  I    L  
Sbjct: 302 STLIQLSIHCPKLQALSLSHCELITDDGILHLSNSTCGHERLRVLELDNCLLITDVALEH 361

Query: 356 LGEIPTLKTLQVFGI--VPDGTLQLLKEALPHLQINCSHFTTIARPT 400
           L     L+ L+++    V    ++ ++  LPH++++ ++F  +  PT
Sbjct: 362 LENCRGLERLELYDCQQVTRAGIKRMRAQLPHVKVH-AYFAPVTPPT 407


>gi|6912466 F-box and leucine-rich repeat protein 7 [Homo sapiens]
          Length = 491

 Score = 75.1 bits (183), Expect = 1e-13
 Identities = 72/274 (26%), Positives = 124/274 (45%), Gaps = 48/274 (17%)

Query: 96  SWDSLPDELLLGIFSCLCLPELLKVSGVCKRWYRLASDESLWQTLDLTGKNLHPDVTGRL 155
           S D LPD  ++ IFS L   +L + + VC+RWY LA D  LW+T+ LTG+ ++ D   ++
Sbjct: 113 SIDRLPDHSMVQIFSFLPTNQLCRCARVCRRWYNLAWDPRLWRTIRLTGETINVDRALKV 172

Query: 156 LSQGVIAFRCPRSFMDQPLAEHFSPFRVQHMDLSNSVIEVSTLHGILSQCSKLQNLSLEG 215
           L++        R   D P                             + C  L+ +++ G
Sbjct: 173 LTR--------RLCQDTP-----------------------------NVCLMLETVTVSG 195

Query: 216 L-RLSDPIVNTLAK-NSNLVRLNLSGCSGFSEFALQTLLSSCSRLDELNLSWCFDFT--- 270
             RL+D  + T+A+    L RL +SGC   S  A+  ++S C  L+ L++S C   T   
Sbjct: 196 CRRLTDRGLYTIAQCCPELRRLEVSGCYNISNEAVFDVVSLCPNLEHLDVSGCSKVTCIS 255

Query: 271 ---EKHVQVAVAHVSE-TITQLNLSGYRKNLQKSDLSTLVRRCPNLVHLDLSDSVMLKND 326
              E  ++++  H  + +I  L+++     L+   L T+   C  L HL L   V L ++
Sbjct: 256 LTREASIKLSPLHGKQISIRYLDMTDCFV-LEDEGLHTIAAHCTQLTHLYLRRCVRLTDE 314

Query: 327 CFQEF-FQLNYLQHLSLSRCYDIIPETLLELGEI 359
             +        ++ LS+S C  +    L E+ ++
Sbjct: 315 GLRYLVIYCASIKELSVSDCRFVSDFGLREIAKL 348



 Score = 55.5 bits (132), Expect = 9e-08
 Identities = 68/248 (27%), Positives = 117/248 (47%), Gaps = 18/248 (7%)

Query: 113 CLPEL--LKVSGVCKRWYRLASDESLWQTLDLTGKNLHPDVTGRLLSQGVIAFRCPRSFM 170
           C PEL  L+VSG     Y + S+E+++  + L     H DV+G       I+     S  
Sbjct: 210 CCPELRRLEVSGC----YNI-SNEAVFDVVSLCPNLEHLDVSG-CSKVTCISLTREASIK 263

Query: 171 DQPLAEHFSPFRVQHMDLSNS-VIEVSTLHGILSQCSKLQNLSLEG-LRLSDPIVNTLAK 228
             PL  H     ++++D+++  V+E   LH I + C++L +L L   +RL+D  +  L  
Sbjct: 264 LSPL--HGKQISIRYLDMTDCFVLEDEGLHTIAAHCTQLTHLYLRRCVRLTDEGLRYLVI 321

Query: 229 N-SNLVRLNLSGCSGFSEFALQTLLSSCSRLDELNLSWCFDFTEKHVQVAVAHVSETITQ 287
             +++  L++S C   S+F L+ +    SRL  L+++ C   T+  ++    + S+ +  
Sbjct: 322 YCASIKELSVSDCRFVSDFGLREIAKLESRLRYLSIAHCGRVTDVGIRYVAKYCSK-LRY 380

Query: 288 LNLSGYRKNLQKSDLSTLVRRCPNLVHLDLSDSVMLKNDCFQEFFQLN--YLQHLSLSRC 345
           LN  G  + +    +  L + C  L  LD+     L +D   E   LN   L+ LSL  C
Sbjct: 381 LNARGC-EGITDHGVEYLAKNCTKLKSLDIG-KCPLVSDTGLECLALNCFNLKRLSLKSC 438

Query: 346 YDIIPETL 353
             I  + L
Sbjct: 439 ESITGQGL 446



 Score = 35.4 bits (80), Expect = 0.099
 Identities = 26/75 (34%), Positives = 38/75 (50%), Gaps = 5/75 (6%)

Query: 197 TLHGI---LSQCSKLQNLSLEGLRL-SDPIVNTLAKNS-NLVRLNLSGCSGFSEFALQTL 251
           T HG+      C+KL++L +    L SD  +  LA N  NL RL+L  C   +   LQ +
Sbjct: 390 TDHGVEYLAKNCTKLKSLDIGKCPLVSDTGLECLALNCFNLKRLSLKSCESITGQGLQIV 449

Query: 252 LSSCSRLDELNLSWC 266
            ++C  L  LN+  C
Sbjct: 450 AANCFDLQTLNVQDC 464


>gi|54112382 F-box and leucine-rich repeat protein 10 isoform a [Homo
            sapiens]
          Length = 1336

 Score = 58.2 bits (139), Expect = 1e-08
 Identities = 67/287 (23%), Positives = 123/287 (42%), Gaps = 55/287 (19%)

Query: 103  ELLLGIFSCLCLPELLKVSGVCKRWYRLASDESLWQTLDLTG-KNLHPDVTGRLLSQGVI 161
            E+ + +FS L   +L     VC+ W R   D+ LW  +DL   K++ P     L+  G+I
Sbjct: 1068 EVWMAVFSYLSHQDLCVCMRVCRTWNRWCCDKRLWTRIDLNHCKSITP-----LMLSGII 1122

Query: 162  AFRCPRSFMDQPLAEHFSPFRVQHMDLSNSVIEVSTLHGIL--------------SQCSK 207
                      QP++   S   +    LS  +  +  L  ++              S C  
Sbjct: 1123 --------RRQPVSLDLSWTNISKKQLSWLINRLPGLRDLVLSGCSWIAVSALCSSSCPL 1174

Query: 208  LQNLS---LEGLR-------LSDPIVN------TLAKNSNLVRLNLSGCSGFSEFALQTL 251
            L+ L    +EGL+       LS P  N        +K  N+V L L+G    ++ +L+ +
Sbjct: 1175 LRTLDVQWVEGLKDAQMRDLLSPPTDNRPGQMDNRSKLRNIVELRLAGLD-ITDASLRLI 1233

Query: 252  LSSCSRLDELNLSWCFDFTEKHVQVAVA---HVSETITQLNLSGYRKNLQKSDLSTLVRR 308
            +     L +L+LS+C   T++ + +  A      +++T++NLS   K        +  +R
Sbjct: 1234 IRHMPLLSKLHLSYCNHVTDQSINLLTAVGTTTRDSLTEINLSDCNK--VTDQCLSFFKR 1291

Query: 309  CPNLVHLDLSDSVMLKNDCFQEFFQLNYLQHLSLSRCYDIIPETLLE 355
            C N+ H+DL     +  +  ++F     +  +S+S  +  + E LL+
Sbjct: 1292 CGNICHIDLRYCKQVTKEGCEQF-----IAEMSVSVQFGQVEEKLLQ 1333


>gi|54112380 F-box and leucine-rich repeat protein 10 isoform b [Homo
            sapiens]
          Length = 1265

 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 67/276 (24%), Positives = 117/276 (42%), Gaps = 51/276 (18%)

Query: 103  ELLLGIFSCLCLPELLKVSGVCKRWYRLASDESLWQTLDLTG-KNLHPDVTGRLLSQGVI 161
            E+ + +FS L   +L     VC+ W R   D+ LW  +DL   K++ P     L+  G+I
Sbjct: 999  EVWMAVFSYLSHQDLCVCMRVCRTWNRWCCDKRLWTRIDLNHCKSITP-----LMLSGII 1053

Query: 162  AFRCPRSFMDQPLAEHFSPFRVQHMDLSNSVIEVSTLHGIL--------------SQCSK 207
                      QP++   S   +    LS  +  +  L  ++              S C  
Sbjct: 1054 --------RRQPVSLDLSWTNISKKQLSWLINRLPGLRDLVLSGCSWIAVSALCSSSCPL 1105

Query: 208  LQNLS---LEGLR-------LSDPIVN------TLAKNSNLVRLNLSGCSGFSEFALQTL 251
            L+ L    +EGL+       LS P  N        +K  N+V L L+G    ++ +L+ +
Sbjct: 1106 LRTLDVQWVEGLKDAQMRDLLSPPTDNRPGQMDNRSKLRNIVELRLAGLD-ITDASLRLI 1164

Query: 252  LSSCSRLDELNLSWCFDFTEKHVQVAVA---HVSETITQLNLSGYRKNLQKSDLSTLVRR 308
            +     L +L+LS+C   T++ + +  A      +++T++NLS   K        +  +R
Sbjct: 1165 IRHMPLLSKLHLSYCNHVTDQSINLLTAVGTTTRDSLTEINLSDCNK--VTDQCLSFFKR 1222

Query: 309  CPNLVHLDLS-DSVMLKNDCFQEFFQLNYLQHLSLS 343
            C N+ H+DL     + K  C Q   +++  Q  S S
Sbjct: 1223 CGNICHIDLRYCKQVTKEGCEQFIAEMSSFQGRSCS 1258


>gi|16306588 F-box and leucine-rich repeat protein 4 [Homo sapiens]
          Length = 621

 Score = 57.0 bits (136), Expect = 3e-08
 Identities = 83/309 (26%), Positives = 129/309 (41%), Gaps = 70/309 (22%)

Query: 97  WDSLPDELLLGIFSCLCLPELLKVSGVCKRWYRLASDESLWQTLDLTGKNLHPDVTGRLL 156
           +D LP EL+  I + L LP+L +++  CK                             LL
Sbjct: 280 FDKLPYELIQLILNHLTLPDLCRLAQTCK-----------------------------LL 310

Query: 157 SQGVIAFRCPRSFMDQPLAEHFSPFRVQHMDLSN--SVIEVSTLHGILSQCSKLQ--NLS 212
           SQ                     P +  H++L    + ++ ++L  + S+C+ +Q  NLS
Sbjct: 311 SQHCC-----------------DPLQYIHLNLQPYWAKLDDTSLEFLQSRCTLVQWLNLS 353

Query: 213 LEGLR--LSDPIVNTLAK--NSNLVRLNLSGCSGF-SEFALQTLLSSCSRLDELNLSWCF 267
             G R  +S    +   K   S LVRL LS CS F +E  L+ +   C  L  LNLS C 
Sbjct: 354 WTGNRGFISVAGFSRFLKVCGSELVRLELS-CSHFLNETCLEVISEMCPNLQALNLSSC- 411

Query: 268 DFTEKHVQVAVAHVSETITQLNLSGYRKNLQKSDLSTLVRRCPNLVHLDLSDSVMLKN-D 326
              +K    A  H+++  +   L  YR  ++++ L +++  C  L HL L   VM+++ D
Sbjct: 412 ---DKLPPQAFNHIAKLCSLKRLVLYRTKVEQTALLSILNFCSELQHLSLGSCVMIEDYD 468

Query: 327 CFQEFF--QLNYLQHLSLSRCYDIIPETLLELGE-IPTLKTLQVFGIVP-----DGTLQL 378
                   +   L+ L L RC +I    + EL    P L+ L + G  P      G    
Sbjct: 469 VIASMIGAKCKKLRTLDLWRCKNITENGIAELASGCPLLEELDL-GWCPTLQSSTGCFTR 527

Query: 379 LKEALPHLQ 387
           L   LP+LQ
Sbjct: 528 LAHQLPNLQ 536



 Score = 53.9 bits (128), Expect = 3e-07
 Identities = 50/180 (27%), Positives = 84/180 (46%), Gaps = 7/180 (3%)

Query: 183 VQHMDLSNSVIEVSTLHGILSQCSKLQNLSLEGLRLS---DPIVNTL-AKNSNLVRLNLS 238
           ++ + L  + +E + L  IL+ CS+LQ+LSL    +    D I + + AK   L  L+L 
Sbjct: 428 LKRLVLYRTKVEQTALLSILNFCSELQHLSLGSCVMIEDYDVIASMIGAKCKKLRTLDLW 487

Query: 239 GCSGFSEFALQTLLSSCSRLDELNLSWCFDF-TEKHVQVAVAHVSETITQLNLSGYRKNL 297
            C   +E  +  L S C  L+EL+L WC    +       +AH    + +L L+  R ++
Sbjct: 488 RCKNITENGIAELASGCPLLEELDLGWCPTLQSSTGCFTRLAHQLPNLQKLFLTANR-SV 546

Query: 298 QKSDLSTLVRRCPNLVHLDLSDSVMLKNDCFQEFFQ-LNYLQHLSLSRCYDIIPETLLEL 356
             +D+  L   C  L  LD+  + M+     ++  +    L  L +S C  I    +LEL
Sbjct: 547 CDTDIDELACNCTRLQQLDILGTRMVSPASLRKLLESCKDLSLLDVSFCSQIDNRAVLEL 606


>gi|161333854 F-box and leucine-rich repeat protein 13 isoform 2
           [Homo sapiens]
          Length = 690

 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 94/401 (23%), Positives = 156/401 (38%), Gaps = 85/401 (21%)

Query: 77  KDFVIVRRPKLNRENFPGVSWDS--------------LPDELLLGIFSCLCLPELLKVSG 122
           K+ +I++R      NFP  S                 LP+  +L IF  L L +++    
Sbjct: 121 KNRLILKRAAAEESNFPERSSSEVFLVDETLKCDISLLPERAILQIFFYLSLKDVIICGQ 180

Query: 123 VCKRWYRLASDESLWQTLDLTG-KNLHPDV------------TGRLLSQGVI----AFR- 164
           V   W  +    SLW  +D +  KN+ PD               RL  +G +     FR 
Sbjct: 181 VNHAWMLMTQLNSLWNAIDFSSVKNVIPDKYIVSTLQRWRLNVLRLNFRGCLLRPKTFRS 240

Query: 165 --------------CPRSFMDQPLAEHFSPF--RVQHMDLSNSVIEVSTLHGILSQCSKL 208
                         CP +F D+ +  H S     V  ++LSN+ I   T+  +      L
Sbjct: 241 VSHCRNLQELNVSDCP-TFTDESM-RHISEGCPGVLCLNLSNTTITNRTMRLLPRHFHNL 298

Query: 209 QNLSLEGLR-LSDPIVNTLAKNSN---LVRLNLSGCSGFSEFALQTLLSSCSRLDELNLS 264
           QNLSL   R  +D  +  L   +    L+ L+LSGC+  S    + + +SC+ +  L ++
Sbjct: 299 QNLSLAYCRRFTDKGLQYLNLGNGCHKLIYLDLSGCTQISVQGFRYIANSCTGIMHLTIN 358

Query: 265 WCFDFTEKHVQVAV--------------AHVSE-TITQLNLSGYRK-----NLQKSDLS- 303
                T+  V+  V               H+S+ T   L+    RK     N + +D S 
Sbjct: 359 DMPTLTDNCVKALVEKCSRITSLVFTGAPHISDCTFRALSACKLRKIRFEGNKRVTDASF 418

Query: 304 -TLVRRCPNLVHLDLSDSVMLKNDCFQEFFQLNYLQHLSLSRCYDIIPETLLELGEIPTL 362
             + +  PNL H+ ++D   + +   +    L  L  L+L+ C  I    L +  + P  
Sbjct: 419 KFIDKNYPNLSHIYMADCKGITDSSLRSLSPLKQLTVLNLANCVRIGDMGLKQFLDGPAS 478

Query: 363 KTLQVFGI-----VPDGTLQLLKEALPHLQI----NCSHFT 394
             ++   +     + D ++  L E  P+L      NC H T
Sbjct: 479 MRIRELNLSNCVRLSDASVMKLSERCPNLNYLSLRNCEHLT 519



 Score = 38.5 bits (88), Expect = 0.012
 Identities = 35/131 (26%), Positives = 64/131 (48%), Gaps = 20/131 (15%)

Query: 164 RCPR-SFMDQPLAEHFSP---------FRVQHMDLSNSVIEVSTLHGILSQCSKLQNLSL 213
           RCP  +++     EH +          F +  +DLS + I    L+ +LS+  KL+ LS+
Sbjct: 503 RCPNLNYLSLRNCEHLTAQGIGYIVNIFSLVSIDLSGTDISNEGLN-VLSRHKKLKELSV 561

Query: 214 --------EGLRLSDPIVNTL-AKNSNLVRLNLSGCSGFSEFALQTLLSSCSRLDELNLS 264
                   +G++++D  +  L AK   L  L++SGC   ++  L+ L   C +L  L + 
Sbjct: 562 SECYRITDDGIQITDSAMEMLSAKCHYLHILDISGCVLLTDQILEDLQIGCKQLRILKMQ 621

Query: 265 WCFDFTEKHVQ 275
           +C + ++K  Q
Sbjct: 622 YCTNISKKAAQ 632



 Score = 31.6 bits (70), Expect = 1.4
 Identities = 34/130 (26%), Positives = 57/130 (43%), Gaps = 13/130 (10%)

Query: 235 LNLSGCSGFSEFALQTLLSSCSRLDELNLSWCFDFTEKHVQVAVAHVSETITQLNLSGYR 294
           LNLS C   S+ ++  L   C  L+ L+L  C   T + +   V   S  +  ++LSG  
Sbjct: 484 LNLSNCVRLSDASVMKLSERCPNLNYLSLRNCEHLTAQGIGYIVNIFS--LVSIDLSG-- 539

Query: 295 KNLQKSDLSTLVRRCPNLVHLDLSDSVMLKNDCFQ------EFF--QLNYLQHLSLSRCY 346
            ++    L+ L R    L  L +S+   + +D  Q      E    + +YL  L +S C 
Sbjct: 540 TDISNEGLNVLSRH-KKLKELSVSECYRITDDGIQITDSAMEMLSAKCHYLHILDISGCV 598

Query: 347 DIIPETLLEL 356
            +  + L +L
Sbjct: 599 LLTDQILEDL 608


>gi|161333852 F-box and leucine-rich repeat protein 13 isoform 1
           [Homo sapiens]
          Length = 735

 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 94/401 (23%), Positives = 156/401 (38%), Gaps = 85/401 (21%)

Query: 77  KDFVIVRRPKLNRENFPGVSWDS--------------LPDELLLGIFSCLCLPELLKVSG 122
           K+ +I++R      NFP  S                 LP+  +L IF  L L +++    
Sbjct: 121 KNRLILKRAAAEESNFPERSSSEVFLVDETLKCDISLLPERAILQIFFYLSLKDVIICGQ 180

Query: 123 VCKRWYRLASDESLWQTLDLTG-KNLHPDV------------TGRLLSQGVI----AFR- 164
           V   W  +    SLW  +D +  KN+ PD               RL  +G +     FR 
Sbjct: 181 VNHAWMLMTQLNSLWNAIDFSSVKNVIPDKYIVSTLQRWRLNVLRLNFRGCLLRPKTFRS 240

Query: 165 --------------CPRSFMDQPLAEHFSPF--RVQHMDLSNSVIEVSTLHGILSQCSKL 208
                         CP +F D+ +  H S     V  ++LSN+ I   T+  +      L
Sbjct: 241 VSHCRNLQELNVSDCP-TFTDESM-RHISEGCPGVLCLNLSNTTITNRTMRLLPRHFHNL 298

Query: 209 QNLSLEGLR-LSDPIVNTLAKNSN---LVRLNLSGCSGFSEFALQTLLSSCSRLDELNLS 264
           QNLSL   R  +D  +  L   +    L+ L+LSGC+  S    + + +SC+ +  L ++
Sbjct: 299 QNLSLAYCRRFTDKGLQYLNLGNGCHKLIYLDLSGCTQISVQGFRYIANSCTGIMHLTIN 358

Query: 265 WCFDFTEKHVQVAV--------------AHVSE-TITQLNLSGYRK-----NLQKSDLS- 303
                T+  V+  V               H+S+ T   L+    RK     N + +D S 
Sbjct: 359 DMPTLTDNCVKALVEKCSRITSLVFTGAPHISDCTFRALSACKLRKIRFEGNKRVTDASF 418

Query: 304 -TLVRRCPNLVHLDLSDSVMLKNDCFQEFFQLNYLQHLSLSRCYDIIPETLLELGEIPTL 362
             + +  PNL H+ ++D   + +   +    L  L  L+L+ C  I    L +  + P  
Sbjct: 419 KFIDKNYPNLSHIYMADCKGITDSSLRSLSPLKQLTVLNLANCVRIGDMGLKQFLDGPAS 478

Query: 363 KTLQVFGI-----VPDGTLQLLKEALPHLQI----NCSHFT 394
             ++   +     + D ++  L E  P+L      NC H T
Sbjct: 479 MRIRELNLSNCVRLSDASVMKLSERCPNLNYLSLRNCEHLT 519



 Score = 48.9 bits (115), Expect = 9e-06
 Identities = 36/150 (24%), Positives = 74/150 (49%), Gaps = 3/150 (2%)

Query: 200 GILSQCSKLQNLSLEGLRLSDPIVNTLAKNSNLVRLNLSGCSGFSEFALQTLLSSCSRLD 259
           G +     L ++ L G  +S+  +N L+++  L  L++S C   ++  +Q    S   L+
Sbjct: 524 GYIVNIFSLVSIDLSGTDISNEGLNVLSRHKKLKELSVSECYRITDDGIQAFCKSSLILE 583

Query: 260 ELNLSWCFDFTEKHVQVAVAHVSETITQLNLSGYRKNLQKSDLSTLVRRCPNLVHLDLSD 319
            L++S+C   ++  ++ A+A     +T L+++G  K +  S +  L  +C  L  LD+S 
Sbjct: 584 HLDVSYCSQLSDMIIK-ALAIYCINLTSLSIAGCPK-ITDSAMEMLSAKCHYLHILDISG 641

Query: 320 SVMLKNDCFQEF-FQLNYLQHLSLSRCYDI 348
            V+L +   ++       L+ L +  C +I
Sbjct: 642 CVLLTDQILEDLQIGCKQLRILKMQYCTNI 671



 Score = 38.9 bits (89), Expect = 0.009
 Identities = 40/158 (25%), Positives = 70/158 (44%), Gaps = 9/158 (5%)

Query: 235 LNLSGCSGFSEFALQTLLSSCSRLDELNLSWCFDFTEKHVQVAVAHVSETITQLNLSGYR 294
           LNLS C   S+ ++  L   C  L+ L+L  C   T + +   V   S  +  ++LSG  
Sbjct: 484 LNLSNCVRLSDASVMKLSERCPNLNYLSLRNCEHLTAQGIGYIVNIFS--LVSIDLSG-- 539

Query: 295 KNLQKSDLSTLVRRCPNLVHLDLSDSVMLKNDCFQEFFQLN-YLQHLSLSRCYDIIPETL 353
            ++    L+ L R    L  L +S+   + +D  Q F + +  L+HL +S C  +    +
Sbjct: 540 TDISNEGLNVLSRH-KKLKELSVSECYRITDDGIQAFCKSSLILEHLDVSYCSQLSDMII 598

Query: 354 LELG-EIPTLKTLQVFGI--VPDGTLQLLKEALPHLQI 388
             L      L +L + G   + D  +++L     +L I
Sbjct: 599 KALAIYCINLTSLSIAGCPKITDSAMEMLSAKCHYLHI 636



 Score = 36.2 bits (82), Expect = 0.058
 Identities = 26/96 (27%), Positives = 50/96 (52%), Gaps = 3/96 (3%)

Query: 183 VQHMDLSN-SVIEVSTLHGILSQCSKLQNLSLEGL-RLSDPIVNTL-AKNSNLVRLNLSG 239
           ++H+D+S  S +    +  +   C  L +LS+ G  +++D  +  L AK   L  L++SG
Sbjct: 582 LEHLDVSYCSQLSDMIIKALAIYCINLTSLSIAGCPKITDSAMEMLSAKCHYLHILDISG 641

Query: 240 CSGFSEFALQTLLSSCSRLDELNLSWCFDFTEKHVQ 275
           C   ++  L+ L   C +L  L + +C + ++K  Q
Sbjct: 642 CVLLTDQILEDLQIGCKQLRILKMQYCTNISKKAAQ 677


>gi|16306580 F-box and leucine-rich repeat protein 11 [Homo sapiens]
          Length = 1162

 Score = 53.1 bits (126), Expect = 5e-07
 Identities = 64/292 (21%), Positives = 117/292 (40%), Gaps = 55/292 (18%)

Query: 96   SWDSLPDELLLGIFSCLCLPELLKVSGVCKRWYRLASDESLWQTLDLTG-KNLHPDVTGR 154
            SW  +  E+ + +F  L   EL +   VCK WY+   D+ LW  +DL+  K + P     
Sbjct: 891  SW--MQREVWMSVFRYLSRRELCECMRVCKTWYKWCCDKRLWTKIDLSRCKAIVPQALSG 948

Query: 155  LLSQGVIAFRCPRSFMDQPLAEHFSPFRVQHMDLSNSVIEVSTLHGIL------------ 202
            ++ +             QP++   S   +    L+  V  +  L  +L            
Sbjct: 949  IIKR-------------QPVSLDLSWTNISKKQLTWLVNRLPGLKDLLLAGCSWSAVSAL 995

Query: 203  --SQCSKLQNLSLE-GLRLSDPIVNTL-------------AKNSNLVRLNLSGCSGFSEF 246
              S C  L+ L L   + + DP +  L             +K  N+    L+G    ++ 
Sbjct: 996  STSSCPLLRTLDLRWAVGIKDPQIRDLLTPPADKPGQDNRSKLRNMTDFRLAGLD-ITDA 1054

Query: 247  ALQTLLSSCSRLDELNLSWCFDFTEKHVQVAVAHVSET---ITQLNLSGYRKNLQKSDLS 303
             L+ ++     L  L+LS C   T++   +  A  S T   +T+LN++G  K   ++ + 
Sbjct: 1055 TLRLIIRHMPLLSRLDLSHCSHLTDQSSNLLTAVGSSTRYSLTELNMAGCNKLTDQTLI- 1113

Query: 304  TLVRRCPNLVHLDLSDSVMLKNDCFQEFFQLNYLQHLSLSRCYDIIPETLLE 355
              +RR  N+  +DL     +     + F     +  LS++  Y +  E L++
Sbjct: 1114 -YLRRIANVTLIDLRGCKQITRKACEHF-----ISDLSINSLYCLSDEKLIQ 1159


>gi|8923179 F-box and leucine-rich repeat protein 12 [Homo sapiens]
          Length = 326

 Score = 52.4 bits (124), Expect = 8e-07
 Identities = 26/57 (45%), Positives = 35/57 (61%)

Query: 100 LPDELLLGIFSCLCLPELLKVSGVCKRWYRLASDESLWQTLDLTGKNLHPDVTGRLL 156
           LPD +LL IFS L + + +++S VC RW RL  D  LW+ +DLT   + P V   LL
Sbjct: 7   LPDSVLLEIFSYLPVRDRIRISRVCHRWKRLVDDRWLWRHVDLTLYTMRPKVMWHLL 63


>gi|16306576 F-box and leucine-rich repeat protein 6 isoform 1 [Homo
           sapiens]
          Length = 539

 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 48/185 (25%), Positives = 77/185 (41%), Gaps = 36/185 (19%)

Query: 85  PKLNRENFPGVSW-DSLPDELLLGIFSCLC-----LPELLKVSGVCKRWYRLASDESLWQ 138
           P    E  P   W D +P E+L+ IF  L      +P L + + VC+RW   AS  +LW 
Sbjct: 99  PTPTPEEGPDAGWGDRIPLEILVQIFGLLVAADGPMPFLGRAARVCRRWQEAASQPALWH 158

Query: 139 TLDLTGKNLHPDVTGRLLSQGVIAFRCPRSFMDQPLAEHFSPFRVQHMDLSNSVIEVSTL 198
           T+ L+       + GR    GV A +   + ++  +   FS  ++Q + L +   +V  +
Sbjct: 159 TVTLSS-----PLVGRPAKGGVKAEKKLLASLEWLMPNRFS--QLQRLTLIHWKSQVHPV 211

Query: 199 HGILSQCSKLQNLSLEGLRLSDPIVNTLAKNSNLVRLNLSGCSGFSEFALQTLLSSCSRL 258
             ++ +C                          L  L LSGC G +  AL  L  +C +L
Sbjct: 212 LKLVGECC-----------------------PRLTFLKLSGCHGVTADALVMLAKACCQL 248

Query: 259 DELNL 263
             L+L
Sbjct: 249 HSLDL 253


>gi|190194416 F-box and leucine-rich repeat protein 15 [Homo
           sapiens]
          Length = 300

 Score = 49.7 bits (117), Expect = 5e-06
 Identities = 50/177 (28%), Positives = 81/177 (45%), Gaps = 6/177 (3%)

Query: 196 STLHGILSQCSKLQNLSLEGLR--LSDP-IVNTLAKNSNLVRLNLSGCSGFSEFALQTLL 252
           + L  +L     LQ L+L      LSD  +V  LA+N  L  + L GC   S  AL  L 
Sbjct: 77  AALARLLRDAEGLQELALAPCHEWLSDEDLVPVLARNPQLRSVALGGCGQLSRRALGALA 136

Query: 253 SSCSRLDELNLSWCFDFTEKHVQVAVAHVSETITQLNLSGYRKNLQKSDLSTLVRRCPNL 312
             C RL  L+L+ C D+ +      +A     + +L+L+  R+   ++ +    RR   L
Sbjct: 137 EGCPRLQRLSLAHC-DWVDGLALRGLADRCPALEELDLTACRQLKDEAIVYLAQRRGAGL 195

Query: 313 VHLDLSDSVMLKNDCFQEFFQ-LNYLQHLSLSRCYDIIPETLLELGE-IPTLKTLQV 367
             L L+ +  + +   QE  +    L HL L+ C  +  + +  L E  P L++L+V
Sbjct: 196 RSLSLAVNANVGDAAVQELARNCPELHHLDLTGCLRVGSDGVRTLAEYCPVLRSLRV 252


>gi|148922963 F-box and leucine-rich repeat protein 21 [Homo
           sapiens]
          Length = 434

 Score = 49.3 bits (116), Expect = 7e-06
 Identities = 68/340 (20%), Positives = 133/340 (39%), Gaps = 47/340 (13%)

Query: 95  VSWDSLPDELLLGIFSCLCLPELLKVSGVCKRWYRLASDESLW--------QTLDLTGKN 146
           + W SLP  ++L IF  L L +    S VC+RW  +     LW        Q+   + K+
Sbjct: 40  LDWGSLPHHVVLQIFQYLPLLDRACASSVCRRWNEVFHISDLWRKFEFELNQSATSSFKS 99

Query: 147 LHPDVTGRLLSQ-----GVIAFRCPRSFMDQPLA---------------EHFSPFRVQHM 186
            HPD+  +++ +       ++F+   S      A                  S  +   M
Sbjct: 100 THPDLIQQIIKKHFAHLQYVSFKVDSSAESAEAACDILSQLVNCSIQTLGLISTAKPSFM 159

Query: 187 DLSNSVIEVSTLHGILSQCSKLQNLSLEGLRLSDPIVNTL-AKNSNLVRL-NLSGCSGFS 244
           ++S S   VS L  +      L ++ +E   + DP +  L A NS+ +RL  +S C   S
Sbjct: 160 NVSESHF-VSALTVVFINSKSLSSIKIEDTPVDDPSLKILVANNSDTLRLPKMSSCPHVS 218

Query: 245 EFALQTLLSSCSRLDELNLSWCFDFTEKHVQVAVAHVSETITQLNLSGYRKN-------- 296
              +  +   C  L EL L++ +  T++      +     +  L +    +N        
Sbjct: 219 SDGILCVADRCQGLRELALNY-YILTDELFLALSSETHVNLEHLRIDVVSENPGQIKFHA 277

Query: 297 LQKSDLSTLVRRCPNLVHLDLSDSVMLKNDCFQEFFQLNYLQHLSLSRCYDIIPETLLEL 356
           ++K     L++  P +       +V++    ++E F+  + +   ++  Y     + + L
Sbjct: 278 VKKHSWDALIKHSPRV-------NVVMHFFLYEEEFETFFKEETPVTHLYFGRSVSKVVL 330

Query: 357 GEIPTLKTLQVFGIVPDGTLQLLKEALPHLQINCSHFTTI 396
           G +       +  +V    LQ L   L  +  +C++ T +
Sbjct: 331 GRVGLNCPRLIELVVCANDLQPLDNELICIAEHCTNLTAL 370


>gi|157168349 F-box and leucine-rich repeat protein 19 [Homo
           sapiens]
          Length = 694

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 95/378 (25%), Positives = 137/378 (36%), Gaps = 101/378 (26%)

Query: 6   LQEIPDLSSNVATSFTWGWDSSKTSELLSGMGVSALEKEEP-DSENIPQELLSNLGHPES 64
           L+ +PD SS+ + S     DS   S      G S  E E P ++ N  +    + G  E+
Sbjct: 317 LERVPDTSSSSSDS-----DSDSDSS-----GTSLSEDEAPGEARNGRRPARGSSGEKEN 366

Query: 65  PPRKRLKSKGSDKDFV------------------IVRRPKLNREN----FPGVSWDSLPD 102
              +R    GS    +                  +VR P  + E         S   LP 
Sbjct: 367 RGGRRAVRPGSGGPLLSWPLGPAPPPRPPQLERHVVRPPPRSPEPDTLPLAAGSDHPLPR 426

Query: 103 ELLLGIFSCLCLPELLKVSGVCKRWYRLASDESLWQTLDLTGKNLHPDVTGRLLSQGVIA 162
              L +F  L   EL     VC+ W R   D+ LW  +DL+ +     +T  +LS GV+ 
Sbjct: 427 AAWLRVFQHLGPRELCICMRVCRTWSRWCYDKRLWPRMDLSRRK---SLTPPMLS-GVVR 482

Query: 163 FRCPRSFMDQPLAEHFSPFRVQHMDLSNSVIEVSTLHGILSQCSKLQNLSLEG------- 215
            R PR+                 +DLS + +    L  +L++   LQ L L G       
Sbjct: 483 -RQPRA-----------------LDLSWTGVSKKQLMWLLNRLQGLQELVLSGCSWLSVS 524

Query: 216 ---------LRLSDPIVNTLAKNSNL------------------------VRLNLSGCSG 242
                    LRL D       K+S L                          L L+G   
Sbjct: 525 ALGSAPLPALRLLDLRWIEDVKDSQLRELLLPPPDTKPGQTESRGRLQGVAELRLAGLE- 583

Query: 243 FSEFALQTLLSSCSRLDELNLSWCFDFTEKHVQVAVAHVS---ETITQLNLSGYRKNLQK 299
            ++ +L+ LL    +L  L+LS C    +  V +  A  S   ET+  LNL+G  +    
Sbjct: 584 LTDASLRLLLRHAPQLSALDLSHCAHVGDPSVHLLTAPTSPLRETLVHLNLAGCHR--LT 641

Query: 300 SDLSTLVRRCPNLVHLDL 317
                L RRCP L  LDL
Sbjct: 642 DHCLPLFRRCPRLRRLDL 659


>gi|61742136 F-box and leucine-rich repeat protein 6 isoform 2 [Homo
           sapiens]
          Length = 533

 Score = 46.6 bits (109), Expect = 4e-05
 Identities = 49/185 (26%), Positives = 73/185 (39%), Gaps = 42/185 (22%)

Query: 85  PKLNRENFPGVSW-DSLPDELLLGIFSCLC-----LPELLKVSGVCKRWYRLASDESLWQ 138
           P    E  P   W D +P E+L+ IF  L      +P L + + VC+RW   AS  +LW 
Sbjct: 99  PTPTPEEGPDAGWGDRIPLEILVQIFGLLVAADGPMPFLGRAARVCRRWQEAASQPALWH 158

Query: 139 TLDLTGKNLHPDVTGRLLSQGVIAFRCPRSFMDQPLAEHFSPFRVQHMDLSNSVIEVSTL 198
           T+ L+       + GR    GV A +   + ++  +   F                    
Sbjct: 159 TVTLSS-----PLVGRPAKGGVKAEKKLLASLEWLMPNRF-------------------- 193

Query: 199 HGILSQCSKLQNLSLEGLRLSDPIVNTLAKNSNLVRLNLSGCSGFSEFALQTLLSSCSRL 258
                  S+LQ L+L  +     +V        L  L LSGC G +  AL  L  +C +L
Sbjct: 194 -------SQLQRLTL--IHWKSQLVGECC--PRLTFLKLSGCHGVTADALVMLAKACCQL 242

Query: 259 DELNL 263
             L+L
Sbjct: 243 HSLDL 247


>gi|24025682 F-box and leucine-rich repeat protein 16 [Homo sapiens]
          Length = 479

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 46/193 (23%), Positives = 84/193 (43%), Gaps = 14/193 (7%)

Query: 102 DELLLGIFSCLCLPELLKVSGVCKRWYRLASDESLWQTLDLTGKNLHPDVTGRLLSQGVI 161
           +++L G+F      E   ++ VCK W R+      W  L      LH      +L  G  
Sbjct: 99  EKILNGLFWYFSACEKCVLAQVCKAWRRVLYQPKFWAGLTPV---LHAKELYNVLPGGEK 155

Query: 162 AFRCPRSFMDQPLAEHFSPFRVQHMDLSNSVIEVS-TLHGILSQCSKLQNLSLEGLRLSD 220
            F   + F  +   E F    V  +D+   +   + +  G+ +   K   ++  GL +  
Sbjct: 156 EFVNLQGFAARGF-EGFCLVGVSDLDICEFIDNYALSKKGVKAMSLKRSTITDAGLEVM- 213

Query: 221 PIVNTLAKNSNLVRLNLSGCSGFSEFALQTLLSSCSRLDELNLSWCFDFTEKHVQVAVAH 280
                L +   +VRL LSGC+ F+E  L + LS  +R+  L++S C +  +  +  A++ 
Sbjct: 214 -----LEQMQGVVRLELSGCNDFTEAGLWSSLS--ARITSLSVSDCINVADDAI-AAISQ 265

Query: 281 VSETITQLNLSGY 293
           +   + +L+L  Y
Sbjct: 266 LLPNLAELSLQAY 278



 Score = 37.7 bits (86), Expect = 0.020
 Identities = 39/166 (23%), Positives = 77/166 (46%), Gaps = 6/166 (3%)

Query: 222 IVNTLAKNSNLVRLNLSGCSGFSEFALQTLLSSCSRLDELNLSWCFDFTEKHVQVAVAHV 281
           +VN +    NL  L+LSGCS  ++  ++ +  +  +L  L+LSWC   T+    +A+ +V
Sbjct: 312 VVNVVHSLPNLTALSLSGCSKVTDDGVELVAENLRKLRSLDLSWCPRITD----MALEYV 367

Query: 282 SETITQLNLSGYRKNLQKSDLS-TLVRRCPNLVHLDLSDSVMLKNDCFQEFFQLNYLQHL 340
           +  + +L      + ++ +D   + +    +L  L L     +++   +    L  L+ L
Sbjct: 368 ACDLHRLEELVLDRCVRITDTGLSYLSTMSSLRSLYLRWCCQVQDFGLKHLLALGSLRLL 427

Query: 341 SLSRCYDIIPETLLELGEIPTLKTLQVFGIVPDGTLQLLKEALPHL 386
           S + C  +    L  L ++  L+ L++    P  T +L K    HL
Sbjct: 428 SPAGCPLLTTTGLSGLVQLQELEELELTN-CPGATPELFKYFSQHL 472


>gi|22748931 F-box and leucine-rich repeat protein 14 [Homo sapiens]
          Length = 418

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 63/277 (22%), Positives = 119/277 (42%), Gaps = 39/277 (14%)

Query: 103 ELLLGIFSCLCLPELLKVSGVCKRWYRLASDESLWQTLD--LTGKNLHPDVTGRLLSQG- 159
           ELL  IF  L + +  + + VC  W   A  +S+W+ ++  L  +  +P +   L ++G 
Sbjct: 11  ELLAMIFGYLDVRDKGRAAQVCTAWRDAAYHKSVWRGVEAKLHLRRANPSLFPSLQARGI 70

Query: 160 ----VIAFRCPRSFMDQPLAEHFSPFRVQHMDLSN--SVIEVSTLHGILSQCSKLQNLSL 213
               +++ R   S++ Q +A       ++ ++LS   ++ +    H  + +   L+ L+L
Sbjct: 71  RRVQILSLRRSLSYVIQGMA------NIESLNLSGCYNLTDNGLGHAFVQEIGSLRALNL 124

Query: 214 EGLR-LSDPIVNTLAKN-SNLVRLNLSGCSGFSEFALQTLLSSCSRLDELNLSWCFDFTE 271
              + ++D  +  +A+    L  L L GCS  +   L  +     RL  LNL  C   ++
Sbjct: 125 SLCKQITDSSLGRIAQYLKGLEVLELGGCSNITNTGLLLIAWGLQRLKSLNLRSCRHLSD 184

Query: 272 KHVQVAVAHVSETITQLNLSGYRKNLQKSDLSTLVRRCPNLVHLDLSDSVMLKNDCFQEF 331
               V + H         L+G  ++  +         C  L  L L D   L +   +  
Sbjct: 185 ----VGIGH---------LAGMTRSAAEG--------CLGLEQLTLQDCQKLTDLSLKHI 223

Query: 332 FQ-LNYLQHLSLSRCYDIIPETLLELGEIPTLKTLQV 367
            + L  L+ L+LS C  I    LL L  + +L++L +
Sbjct: 224 SRGLTGLRLLNLSFCGGISDAGLLHLSHMGSLRSLNL 260



 Score = 43.1 bits (100), Expect = 5e-04
 Identities = 46/184 (25%), Positives = 83/184 (45%), Gaps = 22/184 (11%)

Query: 202 LSQCSKLQNLSLE-------GLRL---------SDPIVNTLAKNSNLVRLNLSGCSGFSE 245
           L  C KL +LSL+       GLRL         SD  +  L+   +L  LNL  C   S+
Sbjct: 209 LQDCQKLTDLSLKHISRGLTGLRLLNLSFCGGISDAGLLHLSHMGSLRSLNLRSCDNISD 268

Query: 246 FALQTLLSSCSRLDELNLSWCFDFTEKHVQVAVAHVSETITQL-NLSGYRKNLQKSDLST 304
             +  L     RL  L++S+C    +K    ++A++++ +  L +LS    ++    ++ 
Sbjct: 269 TGIMHLAMGSLRLSGLDVSFC----DKVGDQSLAYIAQGLDGLKSLSLCSCHISDDGINR 324

Query: 305 LVRRCPNLVHLDLSDSVMLKNDCFQEFFQ-LNYLQHLSLSRCYDIIPETLLELGEIPTLK 363
           +VR+   L  L++   V + +   +   + L+ L  + L  C  I    L  + ++P LK
Sbjct: 325 MVRQMHGLRTLNIGQCVRITDKGLELIAEHLSQLTGIDLYGCTRITKRGLERITQLPCLK 384

Query: 364 TLQV 367
            L +
Sbjct: 385 VLNL 388


>gi|51873034 F-box and leucine-rich repeat protein 9 [Homo sapiens]
          Length = 223

 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 48/163 (29%), Positives = 73/163 (44%), Gaps = 17/163 (10%)

Query: 198 LHGILSQCSKLQNLSLEGLRLSDPIVNTLAKNSNLVRLNLSGCSGFSEFALQTL-LSSCS 256
           +HG  SQ + L       L+ S P +   A  +        G S  +  ALQ L L++CS
Sbjct: 28  MHGAPSQLASLSLAHCSSLK-SRPELEHQASGTKDACPEPQGPSLLTLRALQELDLTACS 86

Query: 257 RLDELNLSWCFDFTEKHVQVAVAHVSETITQLNLSGYRKNLQKSDLSTLVRRCPNLVHLD 316
           +L + +L+    F +             + QL+LS     L  + L  + R CP+L HL 
Sbjct: 87  KLTDASLAKVLQFLQ-------------LRQLSLS-LLPELTDNGLVAVARGCPSLEHLA 132

Query: 317 LSDSVMLKNDCF-QEFFQLNYLQHLSLSRCYDIIPETLLELGE 358
           LS    L +  + Q       LQHL+LS C  +I +TL  +G+
Sbjct: 133 LSHCSRLSDKGWAQAASSWPRLQHLNLSSCSQLIEQTLDAIGQ 175



 Score = 31.6 bits (70), Expect = 1.4
 Identities = 28/89 (31%), Positives = 45/89 (50%), Gaps = 5/89 (5%)

Query: 183 VQHMDLSNSVIEVSTLHGILSQ---CSKLQNLSLEGL-RLSDPIVNTLAKN-SNLVRLNL 237
           +Q   LS S++   T +G+++    C  L++L+L    RLSD      A +   L  LNL
Sbjct: 100 LQLRQLSLSLLPELTDNGLVAVARGCPSLEHLALSHCSRLSDKGWAQAASSWPRLQHLNL 159

Query: 238 SGCSGFSEFALQTLLSSCSRLDELNLSWC 266
           S CS   E  L  +  +C +L  L+++ C
Sbjct: 160 SSCSQLIEQTLDAIGQACRQLRVLDVATC 188


>gi|16306591 F-box and leucine-rich repeat protein 9 [Homo sapiens]
          Length = 223

 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 48/163 (29%), Positives = 73/163 (44%), Gaps = 17/163 (10%)

Query: 198 LHGILSQCSKLQNLSLEGLRLSDPIVNTLAKNSNLVRLNLSGCSGFSEFALQTL-LSSCS 256
           +HG  SQ + L       L+ S P +   A  +        G S  +  ALQ L L++CS
Sbjct: 28  MHGAPSQLASLSLAHCSSLK-SRPELEHQASGTKDACPEPQGPSLLTLRALQELDLTACS 86

Query: 257 RLDELNLSWCFDFTEKHVQVAVAHVSETITQLNLSGYRKNLQKSDLSTLVRRCPNLVHLD 316
           +L + +L+    F +             + QL+LS     L  + L  + R CP+L HL 
Sbjct: 87  KLTDASLAKVLQFLQ-------------LRQLSLS-LLPELTDNGLVAVARGCPSLEHLA 132

Query: 317 LSDSVMLKNDCF-QEFFQLNYLQHLSLSRCYDIIPETLLELGE 358
           LS    L +  + Q       LQHL+LS C  +I +TL  +G+
Sbjct: 133 LSHCSRLSDKGWAQAASSWPRLQHLNLSSCSQLIEQTLDAIGQ 175



 Score = 31.6 bits (70), Expect = 1.4
 Identities = 28/89 (31%), Positives = 45/89 (50%), Gaps = 5/89 (5%)

Query: 183 VQHMDLSNSVIEVSTLHGILSQ---CSKLQNLSLEGL-RLSDPIVNTLAKN-SNLVRLNL 237
           +Q   LS S++   T +G+++    C  L++L+L    RLSD      A +   L  LNL
Sbjct: 100 LQLRQLSLSLLPELTDNGLVAVARGCPSLEHLALSHCSRLSDKGWAQAASSWPRLQHLNL 159

Query: 238 SGCSGFSEFALQTLLSSCSRLDELNLSWC 266
           S CS   E  L  +  +C +L  L+++ C
Sbjct: 160 SSCSQLIEQTLDAIGQACRQLRVLDVATC 188


>gi|30089926 F-box only protein 11 isoform 1 [Homo sapiens]
          Length = 843

 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 23/58 (39%), Positives = 35/58 (60%), Gaps = 5/58 (8%)

Query: 98  DSLPDELLLGIFSCLCLPELLKVSGVCKRWYRLASDESLWQTL-----DLTGKNLHPD 150
           + LPDE++L IFS L   +L + + VCKR+  LA+D  LW+ L     + T   +HP+
Sbjct: 73  EKLPDEVVLKIFSYLLEQDLCRAACVCKRFSELANDPILWKRLYMEVFEYTRPMMHPE 130


>gi|30089924 F-box only protein 11 isoform 2 [Homo sapiens]
          Length = 686

 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 23/58 (39%), Positives = 35/58 (60%), Gaps = 5/58 (8%)

Query: 98  DSLPDELLLGIFSCLCLPELLKVSGVCKRWYRLASDESLWQTL-----DLTGKNLHPD 150
           + LPDE++L IFS L   +L + + VCKR+  LA+D  LW+ L     + T   +HP+
Sbjct: 73  EKLPDEVVLKIFSYLLEQDLCRAACVCKRFSELANDPILWKRLYMEVFEYTRPMMHPE 130


>gi|30089922 F-box only protein 11 isoform 3 [Homo sapiens]
          Length = 585

 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 23/58 (39%), Positives = 35/58 (60%), Gaps = 5/58 (8%)

Query: 98  DSLPDELLLGIFSCLCLPELLKVSGVCKRWYRLASDESLWQTL-----DLTGKNLHPD 150
           + LPDE++L IFS L   +L + + VCKR+  LA+D  LW+ L     + T   +HP+
Sbjct: 73  EKLPDEVVLKIFSYLLEQDLCRAACVCKRFSELANDPILWKRLYMEVFEYTRPMMHPE 130


>gi|164663798 antagonist of mitotic exit network 1 homolog [Homo
           sapiens]
          Length = 258

 Score = 40.8 bits (94), Expect = 0.002
 Identities = 35/143 (24%), Positives = 70/143 (48%), Gaps = 13/143 (9%)

Query: 187 DLSNSVIEVSTLHGILSQCS-------KLQNLSLEGLRLSDPIVNTLAKNSNLVRLNLSG 239
           ++ + +I++ ++ G ++  +       ++Q L L    +SD  +  L+    L +LNL+ 
Sbjct: 35  NIKDRLIKIMSMQGQITDSNISEILHPEVQTLDLRSCDISDAALLHLSNCRKLKKLNLNA 94

Query: 240 CSG----FSEFALQTLLSSCSRLDELNLSWCFDFTEKHVQVAVAHVSETITQLNLSGYRK 295
             G     +   ++ + SSCS L E +L  C + T++ V VA+A   + +  ++L G   
Sbjct: 95  SKGNRVSVTSEGIKAVASSCSYLHEASLKRCCNLTDEGV-VALALNCQLLKIIDLGGC-L 152

Query: 296 NLQKSDLSTLVRRCPNLVHLDLS 318
           ++    L  L + CP L  +D S
Sbjct: 153 SITDVSLHALGKNCPFLQCVDFS 175


>gi|229576894 F-box and WD repeat domain containing 12 isoform 2
           [Homo sapiens]
          Length = 394

 Score = 39.3 bits (90), Expect = 0.007
 Identities = 22/43 (51%), Positives = 27/43 (62%)

Query: 100 LPDELLLGIFSCLCLPELLKVSGVCKRWYRLASDESLWQTLDL 142
           LPD  L  IFS L L  LL+VS V K W R+A  + LW++L L
Sbjct: 5   LPDLALKRIFSFLDLFGLLQVSQVNKHWNRIADSDYLWRSLSL 47


>gi|229576873 F-box and WD repeat domain containing 12 isoform 1
           [Homo sapiens]
          Length = 464

 Score = 39.3 bits (90), Expect = 0.007
 Identities = 22/43 (51%), Positives = 27/43 (62%)

Query: 100 LPDELLLGIFSCLCLPELLKVSGVCKRWYRLASDESLWQTLDL 142
           LPD  L  IFS L L  LL+VS V K W R+A  + LW++L L
Sbjct: 5   LPDLALKRIFSFLDLFGLLQVSQVNKHWNRIADSDYLWRSLSL 47


>gi|219281831 F-box protein 15 isoform 2 [Homo sapiens]
          Length = 510

 Score = 37.0 bits (84), Expect = 0.034
 Identities = 18/40 (45%), Positives = 24/40 (60%)

Query: 98  DSLPDELLLGIFSCLCLPELLKVSGVCKRWYRLASDESLW 137
           D +P E+LL IFS L    LL    V +R+Y LA+D  +W
Sbjct: 75  DGMPSEILLKIFSYLDAVSLLCTGCVSRRFYHLANDNFIW 114


>gi|16306574 F-box and leucine-rich repeat protein 5 isoform 2 [Homo
           sapiens]
          Length = 565

 Score = 37.0 bits (84), Expect = 0.034
 Identities = 56/232 (24%), Positives = 87/232 (37%), Gaps = 37/232 (15%)

Query: 100 LPDELLLGIFSCLCLPELLKVSGVCKRWYRLASDESLWQTL-------------DLTGKN 146
           LP E++L IFS L   EL + S V  +W +L    SLW+ L               T  +
Sbjct: 82  LPPEVMLSIFSYLNPQELCRCSQVSMKWSQLTKTGSLWKHLYPVHWARGDWYSGPATELD 141

Query: 147 LHPDVTGRLLSQGVIAFRCPRSFMDQPLAEHFSPFRVQHMDLSNSVIEVSTLHGILSQCS 206
             PD     +       R    + +    +       + + +S + +E   LHG++    
Sbjct: 142 TEPD--DEWVKNRKDESRAFHEWDEDADIDESEESAEESIAISIAQMEKRLLHGLIHNVL 199

Query: 207 KLQNLSLEGLRLSDPIVNTLAKNSNLVRLNLSGCSGF------------SEFALQTLLSS 254
                S++ L L+     + A +S +VR  L  C               S F   + L  
Sbjct: 200 PYVGTSVKTLVLA----YSSAVSSKMVRQILELCPNLEHLDLTQTDISDSAFDSWSWLGC 255

Query: 255 CSRLDELNLSWCFDFTEKHVQVAVAHVSETITQL--NLSGYRKNLQKSDLST 304
           C  L  L+LS C    EK   VA+  +S  +  L  + SG+ K       ST
Sbjct: 256 CQSLRHLDLSGC----EKITDVALEKISRALGILTSHQSGFLKTSTSKITST 303



 Score = 32.0 bits (71), Expect = 1.1
 Identities = 16/46 (34%), Positives = 23/46 (50%)

Query: 232 LVRLNLSGCSGFSEFALQTLLSSCSRLDELNLSWCFDFTEKHVQVA 277
           L  LNLSGC   +   LQ L+S+C  L++    +C +    H   A
Sbjct: 502 LEHLNLSGCLTITGAGLQDLVSACPSLNDEYFYYCDNINGPHADTA 547



 Score = 31.2 bits (69), Expect = 1.9
 Identities = 26/106 (24%), Positives = 46/106 (43%), Gaps = 5/106 (4%)

Query: 280 HVSETITQLNLSGYRKNLQKSDLSTLVRRCPNLVHLDLSDSVMLKNDCFQEFFQL---NY 336
           +V  ++  L L+ Y   +    +  ++  CPNL HLDL+ +  + +  F  +  L     
Sbjct: 201 YVGTSVKTLVLA-YSSAVSSKMVRQILELCPNLEHLDLTQT-DISDSAFDSWSWLGCCQS 258

Query: 337 LQHLSLSRCYDIIPETLLELGEIPTLKTLQVFGIVPDGTLQLLKEA 382
           L+HL LS C  I    L ++     + T    G +   T ++   A
Sbjct: 259 LRHLDLSGCEKITDVALEKISRALGILTSHQSGFLKTSTSKITSTA 304


>gi|16306572 F-box and leucine-rich repeat protein 5 isoform 1 [Homo
           sapiens]
          Length = 691

 Score = 37.0 bits (84), Expect = 0.034
 Identities = 56/232 (24%), Positives = 87/232 (37%), Gaps = 37/232 (15%)

Query: 100 LPDELLLGIFSCLCLPELLKVSGVCKRWYRLASDESLWQTL-------------DLTGKN 146
           LP E++L IFS L   EL + S V  +W +L    SLW+ L               T  +
Sbjct: 208 LPPEVMLSIFSYLNPQELCRCSQVSMKWSQLTKTGSLWKHLYPVHWARGDWYSGPATELD 267

Query: 147 LHPDVTGRLLSQGVIAFRCPRSFMDQPLAEHFSPFRVQHMDLSNSVIEVSTLHGILSQCS 206
             PD     +       R    + +    +       + + +S + +E   LHG++    
Sbjct: 268 TEPD--DEWVKNRKDESRAFHEWDEDADIDESEESAEESIAISIAQMEKRLLHGLIHNVL 325

Query: 207 KLQNLSLEGLRLSDPIVNTLAKNSNLVRLNLSGCSGF------------SEFALQTLLSS 254
                S++ L L+     + A +S +VR  L  C               S F   + L  
Sbjct: 326 PYVGTSVKTLVLA----YSSAVSSKMVRQILELCPNLEHLDLTQTDISDSAFDSWSWLGC 381

Query: 255 CSRLDELNLSWCFDFTEKHVQVAVAHVSETITQL--NLSGYRKNLQKSDLST 304
           C  L  L+LS C    EK   VA+  +S  +  L  + SG+ K       ST
Sbjct: 382 CQSLRHLDLSGC----EKITDVALEKISRALGILTSHQSGFLKTSTSKITST 429



 Score = 32.0 bits (71), Expect = 1.1
 Identities = 16/46 (34%), Positives = 23/46 (50%)

Query: 232 LVRLNLSGCSGFSEFALQTLLSSCSRLDELNLSWCFDFTEKHVQVA 277
           L  LNLSGC   +   LQ L+S+C  L++    +C +    H   A
Sbjct: 628 LEHLNLSGCLTITGAGLQDLVSACPSLNDEYFYYCDNINGPHADTA 673



 Score = 31.2 bits (69), Expect = 1.9
 Identities = 26/106 (24%), Positives = 46/106 (43%), Gaps = 5/106 (4%)

Query: 280 HVSETITQLNLSGYRKNLQKSDLSTLVRRCPNLVHLDLSDSVMLKNDCFQEFFQL---NY 336
           +V  ++  L L+ Y   +    +  ++  CPNL HLDL+ +  + +  F  +  L     
Sbjct: 327 YVGTSVKTLVLA-YSSAVSSKMVRQILELCPNLEHLDLTQT-DISDSAFDSWSWLGCCQS 384

Query: 337 LQHLSLSRCYDIIPETLLELGEIPTLKTLQVFGIVPDGTLQLLKEA 382
           L+HL LS C  I    L ++     + T    G +   T ++   A
Sbjct: 385 LRHLDLSGCEKITDVALEKISRALGILTSHQSGFLKTSTSKITSTA 430


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.135    0.410 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,486,502
Number of Sequences: 37866
Number of extensions: 727386
Number of successful extensions: 2171
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 57
Number of HSP's successfully gapped in prelim test: 45
Number of HSP's that attempted gapping in prelim test: 1997
Number of HSP's gapped (non-prelim): 159
length of query: 424
length of database: 18,247,518
effective HSP length: 105
effective length of query: 319
effective length of database: 14,271,588
effective search space: 4552636572
effective search space used: 4552636572
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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