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Search of human proteins with 162951877
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|162951877 scinderin isoform 1 [Homo sapiens]
(715 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|162951877 scinderin isoform 1 [Homo sapiens] 1457 0.0
gi|14916473 scinderin isoform 2 [Homo sapiens] 954 0.0
gi|4504165 gelsolin isoform a precursor [Homo sapiens] 915 0.0
gi|38044288 gelsolin isoform b [Homo sapiens] 915 0.0
gi|189083782 gelsolin isoform c [Homo sapiens] 915 0.0
gi|189083780 gelsolin isoform c [Homo sapiens] 915 0.0
gi|189083778 gelsolin isoform b [Homo sapiens] 915 0.0
gi|189083776 gelsolin isoform b [Homo sapiens] 915 0.0
gi|189083774 gelsolin isoform b [Homo sapiens] 915 0.0
gi|189083772 gelsolin isoform b [Homo sapiens] 915 0.0
gi|17572824 advillin [Homo sapiens] 685 0.0
gi|194394237 villin 1 [Homo sapiens] 668 0.0
gi|94721268 villin-like protein [Homo sapiens] 505 e-143
gi|63252913 gelsolin-like capping protein [Homo sapiens] 352 9e-97
gi|4503743 flightless I homolog [Homo sapiens] 280 4e-75
gi|150417973 supervillin isoform 2 [Homo sapiens] 135 2e-31
gi|150417971 supervillin isoform 1 [Homo sapiens] 135 2e-31
gi|41872646 cullin 7 [Homo sapiens] 31 3.5
gi|112382214 SEC24 (S. cerevisiae) homolog B isoform b [Homo sap... 31 3.5
gi|112382212 SEC24 (S. cerevisiae) homolog B isoform a [Homo sap... 31 3.5
gi|115583667 sodium channel, voltage-gated, type XI, alpha [Homo... 30 6.0
gi|52317263 olfactory receptor, family 4, subfamily N, member 2 ... 30 6.0
>gi|162951877 scinderin isoform 1 [Homo sapiens]
Length = 715
Score = 1457 bits (3772), Expect = 0.0
Identities = 715/715 (100%), Positives = 715/715 (100%)
Query: 1 MARELYHEEFARAGKQAGLQVWRIEKLELVPVPQSAHGDFYVGDAYLVLHTAKTSRGFTY 60
MARELYHEEFARAGKQAGLQVWRIEKLELVPVPQSAHGDFYVGDAYLVLHTAKTSRGFTY
Sbjct: 1 MARELYHEEFARAGKQAGLQVWRIEKLELVPVPQSAHGDFYVGDAYLVLHTAKTSRGFTY 60
Query: 61 HLHFWLGKECSQDESTAAAIFTVQMDDYLGGKPVQNRELQGYESNDFVSYFKGGLKYKAG 120
HLHFWLGKECSQDESTAAAIFTVQMDDYLGGKPVQNRELQGYESNDFVSYFKGGLKYKAG
Sbjct: 61 HLHFWLGKECSQDESTAAAIFTVQMDDYLGGKPVQNRELQGYESNDFVSYFKGGLKYKAG 120
Query: 121 GVASGLNHVLTNDLTAKRLLHVKGRRVVRATEVPLSWDSFNKGDCFIIDLGTEIYQWCGS 180
GVASGLNHVLTNDLTAKRLLHVKGRRVVRATEVPLSWDSFNKGDCFIIDLGTEIYQWCGS
Sbjct: 121 GVASGLNHVLTNDLTAKRLLHVKGRRVVRATEVPLSWDSFNKGDCFIIDLGTEIYQWCGS 180
Query: 181 SCNKYERLKANQVATGIRYNERKGRSELIVVEEGSEPSELIKVLGEKPELPDGGDDDDII 240
SCNKYERLKANQVATGIRYNERKGRSELIVVEEGSEPSELIKVLGEKPELPDGGDDDDII
Sbjct: 181 SCNKYERLKANQVATGIRYNERKGRSELIVVEEGSEPSELIKVLGEKPELPDGGDDDDII 240
Query: 241 ADISNRKMAKLYMVSDASGSMRVTVVAEENPFSMAMLLSEECFILDHGAAKQIFVWKGKD 300
ADISNRKMAKLYMVSDASGSMRVTVVAEENPFSMAMLLSEECFILDHGAAKQIFVWKGKD
Sbjct: 241 ADISNRKMAKLYMVSDASGSMRVTVVAEENPFSMAMLLSEECFILDHGAAKQIFVWKGKD 300
Query: 301 ANPQERKAAMKTAEEFLQQMNYSKNTQIQVLPEGGETPIFKQFFKDWRDKDQSDGFGKVY 360
ANPQERKAAMKTAEEFLQQMNYSKNTQIQVLPEGGETPIFKQFFKDWRDKDQSDGFGKVY
Sbjct: 301 ANPQERKAAMKTAEEFLQQMNYSKNTQIQVLPEGGETPIFKQFFKDWRDKDQSDGFGKVY 360
Query: 361 VTEKVAQIKQIPFDASKLHSSPQMAAQHNMVDDGSGKVEIWRVENNGRIQVDQNSYGEFY 420
VTEKVAQIKQIPFDASKLHSSPQMAAQHNMVDDGSGKVEIWRVENNGRIQVDQNSYGEFY
Sbjct: 361 VTEKVAQIKQIPFDASKLHSSPQMAAQHNMVDDGSGKVEIWRVENNGRIQVDQNSYGEFY 420
Query: 421 GGDCYIILYTYPRGQIIYTWQGANATRDELTTSAFLTVQLDRSLGGQAVQIRVSQGKEPV 480
GGDCYIILYTYPRGQIIYTWQGANATRDELTTSAFLTVQLDRSLGGQAVQIRVSQGKEPV
Sbjct: 421 GGDCYIILYTYPRGQIIYTWQGANATRDELTTSAFLTVQLDRSLGGQAVQIRVSQGKEPV 480
Query: 481 HLLSLFKDKPLIIYKNGTSKKGGQAPAPPTRLFQVRRNLASITRIVEVDVDANSLNSNDV 540
HLLSLFKDKPLIIYKNGTSKKGGQAPAPPTRLFQVRRNLASITRIVEVDVDANSLNSNDV
Sbjct: 481 HLLSLFKDKPLIIYKNGTSKKGGQAPAPPTRLFQVRRNLASITRIVEVDVDANSLNSNDV 540
Query: 541 FVLKLPQNSGYIWVGKGASQEEEKGAEYVASVLKCKTLRIQEGEEPEEFWNSLGGKKDYQ 600
FVLKLPQNSGYIWVGKGASQEEEKGAEYVASVLKCKTLRIQEGEEPEEFWNSLGGKKDYQ
Sbjct: 541 FVLKLPQNSGYIWVGKGASQEEEKGAEYVASVLKCKTLRIQEGEEPEEFWNSLGGKKDYQ 600
Query: 601 TSPLLETQAEDHPPRLYGCSNKTGRFVIEEIPGEFTQDDLAEDDVMLLDAWEQIFIWIGK 660
TSPLLETQAEDHPPRLYGCSNKTGRFVIEEIPGEFTQDDLAEDDVMLLDAWEQIFIWIGK
Sbjct: 601 TSPLLETQAEDHPPRLYGCSNKTGRFVIEEIPGEFTQDDLAEDDVMLLDAWEQIFIWIGK 660
Query: 661 DANEVEKKESLKSAKMYLETDPSGRDKRTPIVIIKQGHEPPTFTGWFLGWDSSKW 715
DANEVEKKESLKSAKMYLETDPSGRDKRTPIVIIKQGHEPPTFTGWFLGWDSSKW
Sbjct: 661 DANEVEKKESLKSAKMYLETDPSGRDKRTPIVIIKQGHEPPTFTGWFLGWDSSKW 715
>gi|14916473 scinderin isoform 2 [Homo sapiens]
Length = 468
Score = 954 bits (2466), Expect = 0.0
Identities = 468/468 (100%), Positives = 468/468 (100%)
Query: 248 MAKLYMVSDASGSMRVTVVAEENPFSMAMLLSEECFILDHGAAKQIFVWKGKDANPQERK 307
MAKLYMVSDASGSMRVTVVAEENPFSMAMLLSEECFILDHGAAKQIFVWKGKDANPQERK
Sbjct: 1 MAKLYMVSDASGSMRVTVVAEENPFSMAMLLSEECFILDHGAAKQIFVWKGKDANPQERK 60
Query: 308 AAMKTAEEFLQQMNYSKNTQIQVLPEGGETPIFKQFFKDWRDKDQSDGFGKVYVTEKVAQ 367
AAMKTAEEFLQQMNYSKNTQIQVLPEGGETPIFKQFFKDWRDKDQSDGFGKVYVTEKVAQ
Sbjct: 61 AAMKTAEEFLQQMNYSKNTQIQVLPEGGETPIFKQFFKDWRDKDQSDGFGKVYVTEKVAQ 120
Query: 368 IKQIPFDASKLHSSPQMAAQHNMVDDGSGKVEIWRVENNGRIQVDQNSYGEFYGGDCYII 427
IKQIPFDASKLHSSPQMAAQHNMVDDGSGKVEIWRVENNGRIQVDQNSYGEFYGGDCYII
Sbjct: 121 IKQIPFDASKLHSSPQMAAQHNMVDDGSGKVEIWRVENNGRIQVDQNSYGEFYGGDCYII 180
Query: 428 LYTYPRGQIIYTWQGANATRDELTTSAFLTVQLDRSLGGQAVQIRVSQGKEPVHLLSLFK 487
LYTYPRGQIIYTWQGANATRDELTTSAFLTVQLDRSLGGQAVQIRVSQGKEPVHLLSLFK
Sbjct: 181 LYTYPRGQIIYTWQGANATRDELTTSAFLTVQLDRSLGGQAVQIRVSQGKEPVHLLSLFK 240
Query: 488 DKPLIIYKNGTSKKGGQAPAPPTRLFQVRRNLASITRIVEVDVDANSLNSNDVFVLKLPQ 547
DKPLIIYKNGTSKKGGQAPAPPTRLFQVRRNLASITRIVEVDVDANSLNSNDVFVLKLPQ
Sbjct: 241 DKPLIIYKNGTSKKGGQAPAPPTRLFQVRRNLASITRIVEVDVDANSLNSNDVFVLKLPQ 300
Query: 548 NSGYIWVGKGASQEEEKGAEYVASVLKCKTLRIQEGEEPEEFWNSLGGKKDYQTSPLLET 607
NSGYIWVGKGASQEEEKGAEYVASVLKCKTLRIQEGEEPEEFWNSLGGKKDYQTSPLLET
Sbjct: 301 NSGYIWVGKGASQEEEKGAEYVASVLKCKTLRIQEGEEPEEFWNSLGGKKDYQTSPLLET 360
Query: 608 QAEDHPPRLYGCSNKTGRFVIEEIPGEFTQDDLAEDDVMLLDAWEQIFIWIGKDANEVEK 667
QAEDHPPRLYGCSNKTGRFVIEEIPGEFTQDDLAEDDVMLLDAWEQIFIWIGKDANEVEK
Sbjct: 361 QAEDHPPRLYGCSNKTGRFVIEEIPGEFTQDDLAEDDVMLLDAWEQIFIWIGKDANEVEK 420
Query: 668 KESLKSAKMYLETDPSGRDKRTPIVIIKQGHEPPTFTGWFLGWDSSKW 715
KESLKSAKMYLETDPSGRDKRTPIVIIKQGHEPPTFTGWFLGWDSSKW
Sbjct: 421 KESLKSAKMYLETDPSGRDKRTPIVIIKQGHEPPTFTGWFLGWDSSKW 468
Score = 132 bits (333), Expect = 9e-31
Identities = 98/336 (29%), Positives = 161/336 (47%), Gaps = 30/336 (8%)
Query: 19 LQVWRIEKLELVPVPQSAHGDFYVGDAYLVLHTAKTSRGFTYHLHFWLGKECSQDESTAA 78
+++WR+E + V Q+++G+FY GD Y++L+T + ++ W G ++DE T +
Sbjct: 151 VEIWRVENNGRIQVDQNSYGEFYGGDCYIILYTYPRGQ----IIYTWQGANATRDELTTS 206
Query: 79 AIFTVQMDDYLGGKPVQNRELQGYESNDFVSYFKGG--LKYKAGGVASGLNHVLTNDLTA 136
A TVQ+D LGG+ VQ R QG E +S FK + YK G G
Sbjct: 207 AFLTVQLDRSLGGQAVQIRVSQGKEPVHLLSLFKDKPLIIYKNGTSKKGGQ----APAPP 262
Query: 137 KRLLHVKGR--RVVRATEVPLSWDSFNKGDCFIIDLGTEI-YQWCGSSCNKYERLKANQV 193
RL V+ + R EV + +S N D F++ L Y W G ++ E A V
Sbjct: 263 TRLFQVRRNLASITRIVEVDVDANSLNSNDVFVLKLPQNSGYIWVGKGASQEEEKGAEYV 322
Query: 194 ATGIRYNERKGRSELIVVEEGSEPSELIKVLGEKPELPDGGDDDDIIADISNRKMAKLYM 253
A+ + + + + ++EG EP E LG K + ++ + +LY
Sbjct: 323 ASVL-------KCKTLRIQEGEEPEEFWNSLGGKKDY----QTSPLLETQAEDHPPRLYG 371
Query: 254 VSDASGSMRVTVVAEENPFSMAMLLSEECFILDHGAAKQIFVWKGKDANPQERKAAMKTA 313
S+ +G + + E F+ L ++ +LD A +QIF+W GKDAN E+K ++K+A
Sbjct: 372 CSNKTGRFVIEEIPGE--FTQDDLAEDDVMLLD--AWEQIFIWIGKDANEVEKKESLKSA 427
Query: 314 EEFLQ--QMNYSKNTQIQVLPEGGETPIFKQFFKDW 347
+ +L+ K T I ++ +G E P F +F W
Sbjct: 428 KMYLETDPSGRDKRTPIVIIKQGHEPPTFTGWFLGW 463
Score = 45.1 bits (105), Expect = 2e-04
Identities = 99/490 (20%), Positives = 179/490 (36%), Gaps = 93/490 (18%)
Query: 145 RRVVRATEVPLSWDSFNKGDCFIIDLGT--EIYQWCGSSCNKYERLKANQVATGI--RYN 200
R V A E P S +CFI+D G +I+ W G N ER A + A + N
Sbjct: 15 RVTVVAEENPFSMAMLLSEECFILDHGAAKQIFVWKGKDANPQERKAAMKTAEEFLQQMN 74
Query: 201 ERKGRSELIVVEEGSEP--SELIKVLGEKPELPDGGD--DDDIIADI------------S 244
K ++ E G P + K +K + G + +A I S
Sbjct: 75 YSKNTQIQVLPEGGETPIFKQFFKDWRDKDQSDGFGKVYVTEKVAQIKQIPFDASKLHSS 134
Query: 245 NRKMAKLYMVSDASGSMRVTVVAEENPF-----SMAMLLSEECFIL--DHGAAKQIFVWK 297
+ A+ MV D SG + + V S +C+I+ + + I+ W+
Sbjct: 135 PQMAAQHNMVDDGSGKVEIWRVENNGRIQVDQNSYGEFYGGDCYIILYTYPRGQIIYTWQ 194
Query: 298 GKDANPQERKAAMKTAEEFLQQMNYSKNTQ-IQVLPEGGETPIFKQFFKDWRDKDQSDGF 356
G +A E + T+ Q++ S Q +Q+ G+ P+ ++DK
Sbjct: 195 GANATRDE----LTTSAFLTVQLDRSLGGQAVQIRVSQGKEPV--HLLSLFKDKPLI--- 245
Query: 357 GKVYVTEKVAQIKQIPFDASKLHSSPQMAAQHNMVDDGSGKVEIWRVENNGRIQVDQNSY 416
+Y + Q P ++L + A + + + VD NS
Sbjct: 246 --IYKNGTSKKGGQAPAPPTRLFQVRRNLASITRIVE---------------VDVDANSL 288
Query: 417 GEFYGGDCYIILYTYPRGQIIYTWQGANATRDELTTSAFLTVQLDRSLGGQAVQIRVSQG 476
D +++ G Y W G A+++E + ++ L + +R+ +G
Sbjct: 289 N---SNDVFVLKLPQNSG---YIWVGKGASQEEEKGAEYVASVL------KCKTLRIQEG 336
Query: 477 KEPVHLLSL------FKDKPLIIYKNGTSKKGGQAPAPPTRLFQVRRNLAS-ITRIVEVD 529
+EP + ++ PL+ QA P RL+ + + +
Sbjct: 337 EEPEEFWNSLGGKKDYQTSPLL---------ETQAEDHPPRLYGCSNKTGRFVIEEIPGE 387
Query: 530 VDANSLNSNDVFVLKLPQNSGYIWVGKGASQEEEKGAEYVASVL----------KCKTLR 579
+ L +DV +L + +IW+GK A++ E+K + A + + +
Sbjct: 388 FTQDDLAEDDVMLLDAWEQI-FIWIGKDANEVEKKESLKSAKMYLETDPSGRDKRTPIVI 446
Query: 580 IQEGEEPEEF 589
I++G EP F
Sbjct: 447 IKQGHEPPTF 456
>gi|4504165 gelsolin isoform a precursor [Homo sapiens]
Length = 782
Score = 915 bits (2366), Expect = 0.0
Identities = 431/715 (60%), Positives = 547/715 (76%), Gaps = 8/715 (1%)
Query: 7 HEEFARAGKQAGLQVWRIEKLELVPVPQSAHGDFYVGDAYLVLHTAKTSRG-FTYHLHFW 65
H EF +AGK+ GLQ+WR+EK +LVPVP + +GDF+ GDAY++L T + G Y LH+W
Sbjct: 56 HPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYDLHYW 115
Query: 66 LGKECSQDESTAAAIFTVQMDDYLGGKPVQNRELQGYESNDFVSYFKGGLKYKAGGVASG 125
LG ECSQDES AAAIFTVQ+DDYL G+ VQ+RE+QG+ES F+ YFK GLKYK GGVASG
Sbjct: 116 LGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGVASG 175
Query: 126 LNHVLTNDLTAKRLLHVKGRRVVRATEVPLSWDSFNKGDCFIIDLGTEIYQWCGSSCNKY 185
HV+ N++ +RL VKGRRVVRATEVP+SW+SFN GDCFI+DLG I+QWCGS+ N+Y
Sbjct: 176 FKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNRY 235
Query: 186 ERLKANQVATGIRYNERKGRSELIVVEEGSEPSELIKVLGEKPELPDGGDDDDIIADISN 245
ERLKA QV+ GIR NER GR+ + V EEG+EP +++VLG KP LP G +D D +N
Sbjct: 236 ERLKATQVSKGIRDNERSGRARVHVSEEGTEPEAMLQVLGPKPALP-AGTEDTAKEDAAN 294
Query: 246 RKMAKLYMVSDASGSMRVTVVAEENPFSMAMLLSEECFILDHGAAKQIFVWKGKDANPQE 305
RK+AKLY VS+ +G+M V++VA+ENPF+ L SE+CFILDHG +IFVWKGK AN +E
Sbjct: 295 RKLAKLYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDGKIFVWKGKQANTEE 354
Query: 306 RKAAMKTAEEFLQQMNYSKNTQIQVLPEGGETPIFKQFFKDWRDKDQSDGFGKVYVTEKV 365
RKAA+KTA +F+ +M+Y K TQ+ VLPEGGETP+FKQFFK+WRD DQ+DG G Y++ +
Sbjct: 355 RKAALKTASDFITKMDYPKQTQVSVLPEGGETPLFKQFFKNWRDPDQTDGLGLSYLSSHI 414
Query: 366 AQIKQIPFDASKLHSSPQMAAQHNMVDDGSGKVEIWRVENNGRIQVDQNSYGEFYGGDCY 425
A ++++PFDA+ LH+S MAAQH M DDG+G+ +IWR+E + ++ VD +YG+FYGGD Y
Sbjct: 415 ANVERVPFDAATLHTSTAMAAQHGMDDDGTGQKQIWRIEGSNKVPVDPATYGQFYGGDSY 474
Query: 426 IILYTY----PRGQIIYTWQGANATRDELTTSAFLTVQLDRSLGGQAVQIRVSQGKEPVH 481
IILY Y +GQIIY WQGA +T+DE+ SA LT QLD LGG VQ RV QGKEP H
Sbjct: 475 IILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKEPAH 534
Query: 482 LLSLFKDKPLIIYKNGTSKKGGQAPAPPTRLFQVRRNLASITRIVEVDVDANSLNSNDVF 541
L+SLF KP+IIYK GTS++GGQ TRLFQVR N A TR VEV A +LNSND F
Sbjct: 535 LMSLFGGKPMIIYKGGTSREGGQTAPASTRLFQVRANSAGATRAVEVLPKAGALNSNDAF 594
Query: 542 VLKLPQNSGYIWVGKGASQEEEKGAEYVASVLKCKTLRIQEGEEPEEFWNSLGGKKDYQT 601
VLK P ++ Y+WVG GAS+ E+ GA+ + VL+ + +++ EG EP+ FW +LGGK Y+T
Sbjct: 595 VLKTP-SAAYLWVGTGASEAEKTGAQELLRVLRAQPVQVAEGSEPDGFWEALGGKAAYRT 653
Query: 602 SPLLETQAED-HPPRLYGCSNKTGRFVIEEIPGEFTQDDLAEDDVMLLDAWEQIFIWIGK 660
SP L+ + D HPPRL+ CSNK GRFVIEE+PGE Q+DLA DDVMLLD W+Q+F+W+GK
Sbjct: 654 SPRLKDKKMDAHPPRLFACSNKIGRFVIEEVPGELMQEDLATDDVMLLDTWDQVFVWVGK 713
Query: 661 DANEVEKKESLKSAKMYLETDPSGRDKRTPIVIIKQGHEPPTFTGWFLGWDSSKW 715
D+ E EK E+L SAK Y+ETDP+ RD+RTPI ++KQG EPP+F GWFLGWD W
Sbjct: 714 DSQEEEKTEALTSAKRYIETDPANRDRRTPITVVKQGFEPPSFVGWFLGWDDDYW 768
>gi|38044288 gelsolin isoform b [Homo sapiens]
Length = 731
Score = 915 bits (2366), Expect = 0.0
Identities = 431/715 (60%), Positives = 547/715 (76%), Gaps = 8/715 (1%)
Query: 7 HEEFARAGKQAGLQVWRIEKLELVPVPQSAHGDFYVGDAYLVLHTAKTSRG-FTYHLHFW 65
H EF +AGK+ GLQ+WR+EK +LVPVP + +GDF+ GDAY++L T + G Y LH+W
Sbjct: 5 HPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYDLHYW 64
Query: 66 LGKECSQDESTAAAIFTVQMDDYLGGKPVQNRELQGYESNDFVSYFKGGLKYKAGGVASG 125
LG ECSQDES AAAIFTVQ+DDYL G+ VQ+RE+QG+ES F+ YFK GLKYK GGVASG
Sbjct: 65 LGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGVASG 124
Query: 126 LNHVLTNDLTAKRLLHVKGRRVVRATEVPLSWDSFNKGDCFIIDLGTEIYQWCGSSCNKY 185
HV+ N++ +RL VKGRRVVRATEVP+SW+SFN GDCFI+DLG I+QWCGS+ N+Y
Sbjct: 125 FKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNRY 184
Query: 186 ERLKANQVATGIRYNERKGRSELIVVEEGSEPSELIKVLGEKPELPDGGDDDDIIADISN 245
ERLKA QV+ GIR NER GR+ + V EEG+EP +++VLG KP LP G +D D +N
Sbjct: 185 ERLKATQVSKGIRDNERSGRARVHVSEEGTEPEAMLQVLGPKPALP-AGTEDTAKEDAAN 243
Query: 246 RKMAKLYMVSDASGSMRVTVVAEENPFSMAMLLSEECFILDHGAAKQIFVWKGKDANPQE 305
RK+AKLY VS+ +G+M V++VA+ENPF+ L SE+CFILDHG +IFVWKGK AN +E
Sbjct: 244 RKLAKLYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDGKIFVWKGKQANTEE 303
Query: 306 RKAAMKTAEEFLQQMNYSKNTQIQVLPEGGETPIFKQFFKDWRDKDQSDGFGKVYVTEKV 365
RKAA+KTA +F+ +M+Y K TQ+ VLPEGGETP+FKQFFK+WRD DQ+DG G Y++ +
Sbjct: 304 RKAALKTASDFITKMDYPKQTQVSVLPEGGETPLFKQFFKNWRDPDQTDGLGLSYLSSHI 363
Query: 366 AQIKQIPFDASKLHSSPQMAAQHNMVDDGSGKVEIWRVENNGRIQVDQNSYGEFYGGDCY 425
A ++++PFDA+ LH+S MAAQH M DDG+G+ +IWR+E + ++ VD +YG+FYGGD Y
Sbjct: 364 ANVERVPFDAATLHTSTAMAAQHGMDDDGTGQKQIWRIEGSNKVPVDPATYGQFYGGDSY 423
Query: 426 IILYTY----PRGQIIYTWQGANATRDELTTSAFLTVQLDRSLGGQAVQIRVSQGKEPVH 481
IILY Y +GQIIY WQGA +T+DE+ SA LT QLD LGG VQ RV QGKEP H
Sbjct: 424 IILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKEPAH 483
Query: 482 LLSLFKDKPLIIYKNGTSKKGGQAPAPPTRLFQVRRNLASITRIVEVDVDANSLNSNDVF 541
L+SLF KP+IIYK GTS++GGQ TRLFQVR N A TR VEV A +LNSND F
Sbjct: 484 LMSLFGGKPMIIYKGGTSREGGQTAPASTRLFQVRANSAGATRAVEVLPKAGALNSNDAF 543
Query: 542 VLKLPQNSGYIWVGKGASQEEEKGAEYVASVLKCKTLRIQEGEEPEEFWNSLGGKKDYQT 601
VLK P ++ Y+WVG GAS+ E+ GA+ + VL+ + +++ EG EP+ FW +LGGK Y+T
Sbjct: 544 VLKTP-SAAYLWVGTGASEAEKTGAQELLRVLRAQPVQVAEGSEPDGFWEALGGKAAYRT 602
Query: 602 SPLLETQAED-HPPRLYGCSNKTGRFVIEEIPGEFTQDDLAEDDVMLLDAWEQIFIWIGK 660
SP L+ + D HPPRL+ CSNK GRFVIEE+PGE Q+DLA DDVMLLD W+Q+F+W+GK
Sbjct: 603 SPRLKDKKMDAHPPRLFACSNKIGRFVIEEVPGELMQEDLATDDVMLLDTWDQVFVWVGK 662
Query: 661 DANEVEKKESLKSAKMYLETDPSGRDKRTPIVIIKQGHEPPTFTGWFLGWDSSKW 715
D+ E EK E+L SAK Y+ETDP+ RD+RTPI ++KQG EPP+F GWFLGWD W
Sbjct: 663 DSQEEEKTEALTSAKRYIETDPANRDRRTPITVVKQGFEPPSFVGWFLGWDDDYW 717
>gi|189083782 gelsolin isoform c [Homo sapiens]
Length = 742
Score = 915 bits (2366), Expect = 0.0
Identities = 431/715 (60%), Positives = 547/715 (76%), Gaps = 8/715 (1%)
Query: 7 HEEFARAGKQAGLQVWRIEKLELVPVPQSAHGDFYVGDAYLVLHTAKTSRG-FTYHLHFW 65
H EF +AGK+ GLQ+WR+EK +LVPVP + +GDF+ GDAY++L T + G Y LH+W
Sbjct: 16 HPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYDLHYW 75
Query: 66 LGKECSQDESTAAAIFTVQMDDYLGGKPVQNRELQGYESNDFVSYFKGGLKYKAGGVASG 125
LG ECSQDES AAAIFTVQ+DDYL G+ VQ+RE+QG+ES F+ YFK GLKYK GGVASG
Sbjct: 76 LGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGVASG 135
Query: 126 LNHVLTNDLTAKRLLHVKGRRVVRATEVPLSWDSFNKGDCFIIDLGTEIYQWCGSSCNKY 185
HV+ N++ +RL VKGRRVVRATEVP+SW+SFN GDCFI+DLG I+QWCGS+ N+Y
Sbjct: 136 FKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNRY 195
Query: 186 ERLKANQVATGIRYNERKGRSELIVVEEGSEPSELIKVLGEKPELPDGGDDDDIIADISN 245
ERLKA QV+ GIR NER GR+ + V EEG+EP +++VLG KP LP G +D D +N
Sbjct: 196 ERLKATQVSKGIRDNERSGRARVHVSEEGTEPEAMLQVLGPKPALP-AGTEDTAKEDAAN 254
Query: 246 RKMAKLYMVSDASGSMRVTVVAEENPFSMAMLLSEECFILDHGAAKQIFVWKGKDANPQE 305
RK+AKLY VS+ +G+M V++VA+ENPF+ L SE+CFILDHG +IFVWKGK AN +E
Sbjct: 255 RKLAKLYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDGKIFVWKGKQANTEE 314
Query: 306 RKAAMKTAEEFLQQMNYSKNTQIQVLPEGGETPIFKQFFKDWRDKDQSDGFGKVYVTEKV 365
RKAA+KTA +F+ +M+Y K TQ+ VLPEGGETP+FKQFFK+WRD DQ+DG G Y++ +
Sbjct: 315 RKAALKTASDFITKMDYPKQTQVSVLPEGGETPLFKQFFKNWRDPDQTDGLGLSYLSSHI 374
Query: 366 AQIKQIPFDASKLHSSPQMAAQHNMVDDGSGKVEIWRVENNGRIQVDQNSYGEFYGGDCY 425
A ++++PFDA+ LH+S MAAQH M DDG+G+ +IWR+E + ++ VD +YG+FYGGD Y
Sbjct: 375 ANVERVPFDAATLHTSTAMAAQHGMDDDGTGQKQIWRIEGSNKVPVDPATYGQFYGGDSY 434
Query: 426 IILYTY----PRGQIIYTWQGANATRDELTTSAFLTVQLDRSLGGQAVQIRVSQGKEPVH 481
IILY Y +GQIIY WQGA +T+DE+ SA LT QLD LGG VQ RV QGKEP H
Sbjct: 435 IILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKEPAH 494
Query: 482 LLSLFKDKPLIIYKNGTSKKGGQAPAPPTRLFQVRRNLASITRIVEVDVDANSLNSNDVF 541
L+SLF KP+IIYK GTS++GGQ TRLFQVR N A TR VEV A +LNSND F
Sbjct: 495 LMSLFGGKPMIIYKGGTSREGGQTAPASTRLFQVRANSAGATRAVEVLPKAGALNSNDAF 554
Query: 542 VLKLPQNSGYIWVGKGASQEEEKGAEYVASVLKCKTLRIQEGEEPEEFWNSLGGKKDYQT 601
VLK P ++ Y+WVG GAS+ E+ GA+ + VL+ + +++ EG EP+ FW +LGGK Y+T
Sbjct: 555 VLKTP-SAAYLWVGTGASEAEKTGAQELLRVLRAQPVQVAEGSEPDGFWEALGGKAAYRT 613
Query: 602 SPLLETQAED-HPPRLYGCSNKTGRFVIEEIPGEFTQDDLAEDDVMLLDAWEQIFIWIGK 660
SP L+ + D HPPRL+ CSNK GRFVIEE+PGE Q+DLA DDVMLLD W+Q+F+W+GK
Sbjct: 614 SPRLKDKKMDAHPPRLFACSNKIGRFVIEEVPGELMQEDLATDDVMLLDTWDQVFVWVGK 673
Query: 661 DANEVEKKESLKSAKMYLETDPSGRDKRTPIVIIKQGHEPPTFTGWFLGWDSSKW 715
D+ E EK E+L SAK Y+ETDP+ RD+RTPI ++KQG EPP+F GWFLGWD W
Sbjct: 674 DSQEEEKTEALTSAKRYIETDPANRDRRTPITVVKQGFEPPSFVGWFLGWDDDYW 728
>gi|189083780 gelsolin isoform c [Homo sapiens]
Length = 742
Score = 915 bits (2366), Expect = 0.0
Identities = 431/715 (60%), Positives = 547/715 (76%), Gaps = 8/715 (1%)
Query: 7 HEEFARAGKQAGLQVWRIEKLELVPVPQSAHGDFYVGDAYLVLHTAKTSRG-FTYHLHFW 65
H EF +AGK+ GLQ+WR+EK +LVPVP + +GDF+ GDAY++L T + G Y LH+W
Sbjct: 16 HPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYDLHYW 75
Query: 66 LGKECSQDESTAAAIFTVQMDDYLGGKPVQNRELQGYESNDFVSYFKGGLKYKAGGVASG 125
LG ECSQDES AAAIFTVQ+DDYL G+ VQ+RE+QG+ES F+ YFK GLKYK GGVASG
Sbjct: 76 LGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGVASG 135
Query: 126 LNHVLTNDLTAKRLLHVKGRRVVRATEVPLSWDSFNKGDCFIIDLGTEIYQWCGSSCNKY 185
HV+ N++ +RL VKGRRVVRATEVP+SW+SFN GDCFI+DLG I+QWCGS+ N+Y
Sbjct: 136 FKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNRY 195
Query: 186 ERLKANQVATGIRYNERKGRSELIVVEEGSEPSELIKVLGEKPELPDGGDDDDIIADISN 245
ERLKA QV+ GIR NER GR+ + V EEG+EP +++VLG KP LP G +D D +N
Sbjct: 196 ERLKATQVSKGIRDNERSGRARVHVSEEGTEPEAMLQVLGPKPALP-AGTEDTAKEDAAN 254
Query: 246 RKMAKLYMVSDASGSMRVTVVAEENPFSMAMLLSEECFILDHGAAKQIFVWKGKDANPQE 305
RK+AKLY VS+ +G+M V++VA+ENPF+ L SE+CFILDHG +IFVWKGK AN +E
Sbjct: 255 RKLAKLYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDGKIFVWKGKQANTEE 314
Query: 306 RKAAMKTAEEFLQQMNYSKNTQIQVLPEGGETPIFKQFFKDWRDKDQSDGFGKVYVTEKV 365
RKAA+KTA +F+ +M+Y K TQ+ VLPEGGETP+FKQFFK+WRD DQ+DG G Y++ +
Sbjct: 315 RKAALKTASDFITKMDYPKQTQVSVLPEGGETPLFKQFFKNWRDPDQTDGLGLSYLSSHI 374
Query: 366 AQIKQIPFDASKLHSSPQMAAQHNMVDDGSGKVEIWRVENNGRIQVDQNSYGEFYGGDCY 425
A ++++PFDA+ LH+S MAAQH M DDG+G+ +IWR+E + ++ VD +YG+FYGGD Y
Sbjct: 375 ANVERVPFDAATLHTSTAMAAQHGMDDDGTGQKQIWRIEGSNKVPVDPATYGQFYGGDSY 434
Query: 426 IILYTY----PRGQIIYTWQGANATRDELTTSAFLTVQLDRSLGGQAVQIRVSQGKEPVH 481
IILY Y +GQIIY WQGA +T+DE+ SA LT QLD LGG VQ RV QGKEP H
Sbjct: 435 IILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKEPAH 494
Query: 482 LLSLFKDKPLIIYKNGTSKKGGQAPAPPTRLFQVRRNLASITRIVEVDVDANSLNSNDVF 541
L+SLF KP+IIYK GTS++GGQ TRLFQVR N A TR VEV A +LNSND F
Sbjct: 495 LMSLFGGKPMIIYKGGTSREGGQTAPASTRLFQVRANSAGATRAVEVLPKAGALNSNDAF 554
Query: 542 VLKLPQNSGYIWVGKGASQEEEKGAEYVASVLKCKTLRIQEGEEPEEFWNSLGGKKDYQT 601
VLK P ++ Y+WVG GAS+ E+ GA+ + VL+ + +++ EG EP+ FW +LGGK Y+T
Sbjct: 555 VLKTP-SAAYLWVGTGASEAEKTGAQELLRVLRAQPVQVAEGSEPDGFWEALGGKAAYRT 613
Query: 602 SPLLETQAED-HPPRLYGCSNKTGRFVIEEIPGEFTQDDLAEDDVMLLDAWEQIFIWIGK 660
SP L+ + D HPPRL+ CSNK GRFVIEE+PGE Q+DLA DDVMLLD W+Q+F+W+GK
Sbjct: 614 SPRLKDKKMDAHPPRLFACSNKIGRFVIEEVPGELMQEDLATDDVMLLDTWDQVFVWVGK 673
Query: 661 DANEVEKKESLKSAKMYLETDPSGRDKRTPIVIIKQGHEPPTFTGWFLGWDSSKW 715
D+ E EK E+L SAK Y+ETDP+ RD+RTPI ++KQG EPP+F GWFLGWD W
Sbjct: 674 DSQEEEKTEALTSAKRYIETDPANRDRRTPITVVKQGFEPPSFVGWFLGWDDDYW 728
>gi|189083778 gelsolin isoform b [Homo sapiens]
Length = 731
Score = 915 bits (2366), Expect = 0.0
Identities = 431/715 (60%), Positives = 547/715 (76%), Gaps = 8/715 (1%)
Query: 7 HEEFARAGKQAGLQVWRIEKLELVPVPQSAHGDFYVGDAYLVLHTAKTSRG-FTYHLHFW 65
H EF +AGK+ GLQ+WR+EK +LVPVP + +GDF+ GDAY++L T + G Y LH+W
Sbjct: 5 HPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYDLHYW 64
Query: 66 LGKECSQDESTAAAIFTVQMDDYLGGKPVQNRELQGYESNDFVSYFKGGLKYKAGGVASG 125
LG ECSQDES AAAIFTVQ+DDYL G+ VQ+RE+QG+ES F+ YFK GLKYK GGVASG
Sbjct: 65 LGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGVASG 124
Query: 126 LNHVLTNDLTAKRLLHVKGRRVVRATEVPLSWDSFNKGDCFIIDLGTEIYQWCGSSCNKY 185
HV+ N++ +RL VKGRRVVRATEVP+SW+SFN GDCFI+DLG I+QWCGS+ N+Y
Sbjct: 125 FKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNRY 184
Query: 186 ERLKANQVATGIRYNERKGRSELIVVEEGSEPSELIKVLGEKPELPDGGDDDDIIADISN 245
ERLKA QV+ GIR NER GR+ + V EEG+EP +++VLG KP LP G +D D +N
Sbjct: 185 ERLKATQVSKGIRDNERSGRARVHVSEEGTEPEAMLQVLGPKPALP-AGTEDTAKEDAAN 243
Query: 246 RKMAKLYMVSDASGSMRVTVVAEENPFSMAMLLSEECFILDHGAAKQIFVWKGKDANPQE 305
RK+AKLY VS+ +G+M V++VA+ENPF+ L SE+CFILDHG +IFVWKGK AN +E
Sbjct: 244 RKLAKLYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDGKIFVWKGKQANTEE 303
Query: 306 RKAAMKTAEEFLQQMNYSKNTQIQVLPEGGETPIFKQFFKDWRDKDQSDGFGKVYVTEKV 365
RKAA+KTA +F+ +M+Y K TQ+ VLPEGGETP+FKQFFK+WRD DQ+DG G Y++ +
Sbjct: 304 RKAALKTASDFITKMDYPKQTQVSVLPEGGETPLFKQFFKNWRDPDQTDGLGLSYLSSHI 363
Query: 366 AQIKQIPFDASKLHSSPQMAAQHNMVDDGSGKVEIWRVENNGRIQVDQNSYGEFYGGDCY 425
A ++++PFDA+ LH+S MAAQH M DDG+G+ +IWR+E + ++ VD +YG+FYGGD Y
Sbjct: 364 ANVERVPFDAATLHTSTAMAAQHGMDDDGTGQKQIWRIEGSNKVPVDPATYGQFYGGDSY 423
Query: 426 IILYTY----PRGQIIYTWQGANATRDELTTSAFLTVQLDRSLGGQAVQIRVSQGKEPVH 481
IILY Y +GQIIY WQGA +T+DE+ SA LT QLD LGG VQ RV QGKEP H
Sbjct: 424 IILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKEPAH 483
Query: 482 LLSLFKDKPLIIYKNGTSKKGGQAPAPPTRLFQVRRNLASITRIVEVDVDANSLNSNDVF 541
L+SLF KP+IIYK GTS++GGQ TRLFQVR N A TR VEV A +LNSND F
Sbjct: 484 LMSLFGGKPMIIYKGGTSREGGQTAPASTRLFQVRANSAGATRAVEVLPKAGALNSNDAF 543
Query: 542 VLKLPQNSGYIWVGKGASQEEEKGAEYVASVLKCKTLRIQEGEEPEEFWNSLGGKKDYQT 601
VLK P ++ Y+WVG GAS+ E+ GA+ + VL+ + +++ EG EP+ FW +LGGK Y+T
Sbjct: 544 VLKTP-SAAYLWVGTGASEAEKTGAQELLRVLRAQPVQVAEGSEPDGFWEALGGKAAYRT 602
Query: 602 SPLLETQAED-HPPRLYGCSNKTGRFVIEEIPGEFTQDDLAEDDVMLLDAWEQIFIWIGK 660
SP L+ + D HPPRL+ CSNK GRFVIEE+PGE Q+DLA DDVMLLD W+Q+F+W+GK
Sbjct: 603 SPRLKDKKMDAHPPRLFACSNKIGRFVIEEVPGELMQEDLATDDVMLLDTWDQVFVWVGK 662
Query: 661 DANEVEKKESLKSAKMYLETDPSGRDKRTPIVIIKQGHEPPTFTGWFLGWDSSKW 715
D+ E EK E+L SAK Y+ETDP+ RD+RTPI ++KQG EPP+F GWFLGWD W
Sbjct: 663 DSQEEEKTEALTSAKRYIETDPANRDRRTPITVVKQGFEPPSFVGWFLGWDDDYW 717
>gi|189083776 gelsolin isoform b [Homo sapiens]
Length = 731
Score = 915 bits (2366), Expect = 0.0
Identities = 431/715 (60%), Positives = 547/715 (76%), Gaps = 8/715 (1%)
Query: 7 HEEFARAGKQAGLQVWRIEKLELVPVPQSAHGDFYVGDAYLVLHTAKTSRG-FTYHLHFW 65
H EF +AGK+ GLQ+WR+EK +LVPVP + +GDF+ GDAY++L T + G Y LH+W
Sbjct: 5 HPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYDLHYW 64
Query: 66 LGKECSQDESTAAAIFTVQMDDYLGGKPVQNRELQGYESNDFVSYFKGGLKYKAGGVASG 125
LG ECSQDES AAAIFTVQ+DDYL G+ VQ+RE+QG+ES F+ YFK GLKYK GGVASG
Sbjct: 65 LGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGVASG 124
Query: 126 LNHVLTNDLTAKRLLHVKGRRVVRATEVPLSWDSFNKGDCFIIDLGTEIYQWCGSSCNKY 185
HV+ N++ +RL VKGRRVVRATEVP+SW+SFN GDCFI+DLG I+QWCGS+ N+Y
Sbjct: 125 FKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNRY 184
Query: 186 ERLKANQVATGIRYNERKGRSELIVVEEGSEPSELIKVLGEKPELPDGGDDDDIIADISN 245
ERLKA QV+ GIR NER GR+ + V EEG+EP +++VLG KP LP G +D D +N
Sbjct: 185 ERLKATQVSKGIRDNERSGRARVHVSEEGTEPEAMLQVLGPKPALP-AGTEDTAKEDAAN 243
Query: 246 RKMAKLYMVSDASGSMRVTVVAEENPFSMAMLLSEECFILDHGAAKQIFVWKGKDANPQE 305
RK+AKLY VS+ +G+M V++VA+ENPF+ L SE+CFILDHG +IFVWKGK AN +E
Sbjct: 244 RKLAKLYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDGKIFVWKGKQANTEE 303
Query: 306 RKAAMKTAEEFLQQMNYSKNTQIQVLPEGGETPIFKQFFKDWRDKDQSDGFGKVYVTEKV 365
RKAA+KTA +F+ +M+Y K TQ+ VLPEGGETP+FKQFFK+WRD DQ+DG G Y++ +
Sbjct: 304 RKAALKTASDFITKMDYPKQTQVSVLPEGGETPLFKQFFKNWRDPDQTDGLGLSYLSSHI 363
Query: 366 AQIKQIPFDASKLHSSPQMAAQHNMVDDGSGKVEIWRVENNGRIQVDQNSYGEFYGGDCY 425
A ++++PFDA+ LH+S MAAQH M DDG+G+ +IWR+E + ++ VD +YG+FYGGD Y
Sbjct: 364 ANVERVPFDAATLHTSTAMAAQHGMDDDGTGQKQIWRIEGSNKVPVDPATYGQFYGGDSY 423
Query: 426 IILYTY----PRGQIIYTWQGANATRDELTTSAFLTVQLDRSLGGQAVQIRVSQGKEPVH 481
IILY Y +GQIIY WQGA +T+DE+ SA LT QLD LGG VQ RV QGKEP H
Sbjct: 424 IILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKEPAH 483
Query: 482 LLSLFKDKPLIIYKNGTSKKGGQAPAPPTRLFQVRRNLASITRIVEVDVDANSLNSNDVF 541
L+SLF KP+IIYK GTS++GGQ TRLFQVR N A TR VEV A +LNSND F
Sbjct: 484 LMSLFGGKPMIIYKGGTSREGGQTAPASTRLFQVRANSAGATRAVEVLPKAGALNSNDAF 543
Query: 542 VLKLPQNSGYIWVGKGASQEEEKGAEYVASVLKCKTLRIQEGEEPEEFWNSLGGKKDYQT 601
VLK P ++ Y+WVG GAS+ E+ GA+ + VL+ + +++ EG EP+ FW +LGGK Y+T
Sbjct: 544 VLKTP-SAAYLWVGTGASEAEKTGAQELLRVLRAQPVQVAEGSEPDGFWEALGGKAAYRT 602
Query: 602 SPLLETQAED-HPPRLYGCSNKTGRFVIEEIPGEFTQDDLAEDDVMLLDAWEQIFIWIGK 660
SP L+ + D HPPRL+ CSNK GRFVIEE+PGE Q+DLA DDVMLLD W+Q+F+W+GK
Sbjct: 603 SPRLKDKKMDAHPPRLFACSNKIGRFVIEEVPGELMQEDLATDDVMLLDTWDQVFVWVGK 662
Query: 661 DANEVEKKESLKSAKMYLETDPSGRDKRTPIVIIKQGHEPPTFTGWFLGWDSSKW 715
D+ E EK E+L SAK Y+ETDP+ RD+RTPI ++KQG EPP+F GWFLGWD W
Sbjct: 663 DSQEEEKTEALTSAKRYIETDPANRDRRTPITVVKQGFEPPSFVGWFLGWDDDYW 717
>gi|189083774 gelsolin isoform b [Homo sapiens]
Length = 731
Score = 915 bits (2366), Expect = 0.0
Identities = 431/715 (60%), Positives = 547/715 (76%), Gaps = 8/715 (1%)
Query: 7 HEEFARAGKQAGLQVWRIEKLELVPVPQSAHGDFYVGDAYLVLHTAKTSRG-FTYHLHFW 65
H EF +AGK+ GLQ+WR+EK +LVPVP + +GDF+ GDAY++L T + G Y LH+W
Sbjct: 5 HPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYDLHYW 64
Query: 66 LGKECSQDESTAAAIFTVQMDDYLGGKPVQNRELQGYESNDFVSYFKGGLKYKAGGVASG 125
LG ECSQDES AAAIFTVQ+DDYL G+ VQ+RE+QG+ES F+ YFK GLKYK GGVASG
Sbjct: 65 LGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGVASG 124
Query: 126 LNHVLTNDLTAKRLLHVKGRRVVRATEVPLSWDSFNKGDCFIIDLGTEIYQWCGSSCNKY 185
HV+ N++ +RL VKGRRVVRATEVP+SW+SFN GDCFI+DLG I+QWCGS+ N+Y
Sbjct: 125 FKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNRY 184
Query: 186 ERLKANQVATGIRYNERKGRSELIVVEEGSEPSELIKVLGEKPELPDGGDDDDIIADISN 245
ERLKA QV+ GIR NER GR+ + V EEG+EP +++VLG KP LP G +D D +N
Sbjct: 185 ERLKATQVSKGIRDNERSGRARVHVSEEGTEPEAMLQVLGPKPALP-AGTEDTAKEDAAN 243
Query: 246 RKMAKLYMVSDASGSMRVTVVAEENPFSMAMLLSEECFILDHGAAKQIFVWKGKDANPQE 305
RK+AKLY VS+ +G+M V++VA+ENPF+ L SE+CFILDHG +IFVWKGK AN +E
Sbjct: 244 RKLAKLYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDGKIFVWKGKQANTEE 303
Query: 306 RKAAMKTAEEFLQQMNYSKNTQIQVLPEGGETPIFKQFFKDWRDKDQSDGFGKVYVTEKV 365
RKAA+KTA +F+ +M+Y K TQ+ VLPEGGETP+FKQFFK+WRD DQ+DG G Y++ +
Sbjct: 304 RKAALKTASDFITKMDYPKQTQVSVLPEGGETPLFKQFFKNWRDPDQTDGLGLSYLSSHI 363
Query: 366 AQIKQIPFDASKLHSSPQMAAQHNMVDDGSGKVEIWRVENNGRIQVDQNSYGEFYGGDCY 425
A ++++PFDA+ LH+S MAAQH M DDG+G+ +IWR+E + ++ VD +YG+FYGGD Y
Sbjct: 364 ANVERVPFDAATLHTSTAMAAQHGMDDDGTGQKQIWRIEGSNKVPVDPATYGQFYGGDSY 423
Query: 426 IILYTY----PRGQIIYTWQGANATRDELTTSAFLTVQLDRSLGGQAVQIRVSQGKEPVH 481
IILY Y +GQIIY WQGA +T+DE+ SA LT QLD LGG VQ RV QGKEP H
Sbjct: 424 IILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKEPAH 483
Query: 482 LLSLFKDKPLIIYKNGTSKKGGQAPAPPTRLFQVRRNLASITRIVEVDVDANSLNSNDVF 541
L+SLF KP+IIYK GTS++GGQ TRLFQVR N A TR VEV A +LNSND F
Sbjct: 484 LMSLFGGKPMIIYKGGTSREGGQTAPASTRLFQVRANSAGATRAVEVLPKAGALNSNDAF 543
Query: 542 VLKLPQNSGYIWVGKGASQEEEKGAEYVASVLKCKTLRIQEGEEPEEFWNSLGGKKDYQT 601
VLK P ++ Y+WVG GAS+ E+ GA+ + VL+ + +++ EG EP+ FW +LGGK Y+T
Sbjct: 544 VLKTP-SAAYLWVGTGASEAEKTGAQELLRVLRAQPVQVAEGSEPDGFWEALGGKAAYRT 602
Query: 602 SPLLETQAED-HPPRLYGCSNKTGRFVIEEIPGEFTQDDLAEDDVMLLDAWEQIFIWIGK 660
SP L+ + D HPPRL+ CSNK GRFVIEE+PGE Q+DLA DDVMLLD W+Q+F+W+GK
Sbjct: 603 SPRLKDKKMDAHPPRLFACSNKIGRFVIEEVPGELMQEDLATDDVMLLDTWDQVFVWVGK 662
Query: 661 DANEVEKKESLKSAKMYLETDPSGRDKRTPIVIIKQGHEPPTFTGWFLGWDSSKW 715
D+ E EK E+L SAK Y+ETDP+ RD+RTPI ++KQG EPP+F GWFLGWD W
Sbjct: 663 DSQEEEKTEALTSAKRYIETDPANRDRRTPITVVKQGFEPPSFVGWFLGWDDDYW 717
>gi|189083772 gelsolin isoform b [Homo sapiens]
Length = 731
Score = 915 bits (2366), Expect = 0.0
Identities = 431/715 (60%), Positives = 547/715 (76%), Gaps = 8/715 (1%)
Query: 7 HEEFARAGKQAGLQVWRIEKLELVPVPQSAHGDFYVGDAYLVLHTAKTSRG-FTYHLHFW 65
H EF +AGK+ GLQ+WR+EK +LVPVP + +GDF+ GDAY++L T + G Y LH+W
Sbjct: 5 HPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYDLHYW 64
Query: 66 LGKECSQDESTAAAIFTVQMDDYLGGKPVQNRELQGYESNDFVSYFKGGLKYKAGGVASG 125
LG ECSQDES AAAIFTVQ+DDYL G+ VQ+RE+QG+ES F+ YFK GLKYK GGVASG
Sbjct: 65 LGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGVASG 124
Query: 126 LNHVLTNDLTAKRLLHVKGRRVVRATEVPLSWDSFNKGDCFIIDLGTEIYQWCGSSCNKY 185
HV+ N++ +RL VKGRRVVRATEVP+SW+SFN GDCFI+DLG I+QWCGS+ N+Y
Sbjct: 125 FKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNRY 184
Query: 186 ERLKANQVATGIRYNERKGRSELIVVEEGSEPSELIKVLGEKPELPDGGDDDDIIADISN 245
ERLKA QV+ GIR NER GR+ + V EEG+EP +++VLG KP LP G +D D +N
Sbjct: 185 ERLKATQVSKGIRDNERSGRARVHVSEEGTEPEAMLQVLGPKPALP-AGTEDTAKEDAAN 243
Query: 246 RKMAKLYMVSDASGSMRVTVVAEENPFSMAMLLSEECFILDHGAAKQIFVWKGKDANPQE 305
RK+AKLY VS+ +G+M V++VA+ENPF+ L SE+CFILDHG +IFVWKGK AN +E
Sbjct: 244 RKLAKLYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDGKIFVWKGKQANTEE 303
Query: 306 RKAAMKTAEEFLQQMNYSKNTQIQVLPEGGETPIFKQFFKDWRDKDQSDGFGKVYVTEKV 365
RKAA+KTA +F+ +M+Y K TQ+ VLPEGGETP+FKQFFK+WRD DQ+DG G Y++ +
Sbjct: 304 RKAALKTASDFITKMDYPKQTQVSVLPEGGETPLFKQFFKNWRDPDQTDGLGLSYLSSHI 363
Query: 366 AQIKQIPFDASKLHSSPQMAAQHNMVDDGSGKVEIWRVENNGRIQVDQNSYGEFYGGDCY 425
A ++++PFDA+ LH+S MAAQH M DDG+G+ +IWR+E + ++ VD +YG+FYGGD Y
Sbjct: 364 ANVERVPFDAATLHTSTAMAAQHGMDDDGTGQKQIWRIEGSNKVPVDPATYGQFYGGDSY 423
Query: 426 IILYTY----PRGQIIYTWQGANATRDELTTSAFLTVQLDRSLGGQAVQIRVSQGKEPVH 481
IILY Y +GQIIY WQGA +T+DE+ SA LT QLD LGG VQ RV QGKEP H
Sbjct: 424 IILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKEPAH 483
Query: 482 LLSLFKDKPLIIYKNGTSKKGGQAPAPPTRLFQVRRNLASITRIVEVDVDANSLNSNDVF 541
L+SLF KP+IIYK GTS++GGQ TRLFQVR N A TR VEV A +LNSND F
Sbjct: 484 LMSLFGGKPMIIYKGGTSREGGQTAPASTRLFQVRANSAGATRAVEVLPKAGALNSNDAF 543
Query: 542 VLKLPQNSGYIWVGKGASQEEEKGAEYVASVLKCKTLRIQEGEEPEEFWNSLGGKKDYQT 601
VLK P ++ Y+WVG GAS+ E+ GA+ + VL+ + +++ EG EP+ FW +LGGK Y+T
Sbjct: 544 VLKTP-SAAYLWVGTGASEAEKTGAQELLRVLRAQPVQVAEGSEPDGFWEALGGKAAYRT 602
Query: 602 SPLLETQAED-HPPRLYGCSNKTGRFVIEEIPGEFTQDDLAEDDVMLLDAWEQIFIWIGK 660
SP L+ + D HPPRL+ CSNK GRFVIEE+PGE Q+DLA DDVMLLD W+Q+F+W+GK
Sbjct: 603 SPRLKDKKMDAHPPRLFACSNKIGRFVIEEVPGELMQEDLATDDVMLLDTWDQVFVWVGK 662
Query: 661 DANEVEKKESLKSAKMYLETDPSGRDKRTPIVIIKQGHEPPTFTGWFLGWDSSKW 715
D+ E EK E+L SAK Y+ETDP+ RD+RTPI ++KQG EPP+F GWFLGWD W
Sbjct: 663 DSQEEEKTEALTSAKRYIETDPANRDRRTPITVVKQGFEPPSFVGWFLGWDDDYW 717
>gi|17572824 advillin [Homo sapiens]
Length = 819
Score = 685 bits (1768), Expect = 0.0
Identities = 355/721 (49%), Positives = 473/721 (65%), Gaps = 26/721 (3%)
Query: 10 FARAGKQAGLQVWRIEKLELVPVPQSAHGDFYVGDAYLVLHTAKTSRGFTYHLHFWLGKE 69
F G+ VWRIEK+EL VP SAHG+FY GD Y++L T + + + +HFW+GK+
Sbjct: 7 FRAVDNDPGIIVWRIEKMELALVPVSAHGNFYEGDCYVILSTRRVASLLSQDIHFWIGKD 66
Query: 70 CSQDESTAAAIFTVQMDDYLGGKPVQNRELQGYESNDFVSYFKGGLKYKAGGVASGLNHV 129
SQDE + AAI+T Q+DDYLGG PVQ+RE+Q +ES+ F YFK G+ YK GGVASG+ HV
Sbjct: 67 SSQDEQSCAAIYTTQLDDYLGGSPVQHREVQYHESDTFRGYFKQGIIYKQGGVASGMKHV 126
Query: 130 LTNDLTAKRLLHVKGRRVVRATEVPLSWDSFNKGDCFIIDLGTEIYQWCGSSCNKYERLK 189
TN KRLLHVKG+R +RATEV +SWDSFN+GD F++DLG I QW G N ERLK
Sbjct: 127 ETNTYDVKRLLHVKGKRNIRATEVEMSWDSFNRGDVFLLDLGKVIIQWNGPESNSGERLK 186
Query: 190 ANQVATGIRYNERKGRSELIVVEEGSEPS--ELIKVLGE--------KPELPDGGDDDDI 239
A +A IR ER GR+E+ V+E E + EL+KVL + KP +PD
Sbjct: 187 AMLLAKDIRDRERGGRAEIGVIEGDKEAASPELMKVLQDTLGRRSIIKPTVPDE------ 240
Query: 240 IADISNRKMAKLYMVSDASGSMRVTVVAEENPFSMAMLLSEECFILDHGAAKQIFVWKGK 299
I D + LY +SD++G + VT VA P +L ++C+ILD K I+VWKGK
Sbjct: 241 IIDQKQKSTIMLYHISDSAGQLAVTEVA-TRPLVQDLLNHDDCYILDQSGTK-IYVWKGK 298
Query: 300 DANPQERKAAMKTAEEFLQQMNYSKNTQIQVLPEGGETPIFKQFFKDWRDKDQSDGFGKV 359
A E++AAM A F++ +Y +T ++ + +G E+ +FKQ F+ W KDQ+ G GK
Sbjct: 299 GATKAEKQAAMSKALGFIKMKSYPSSTNVETVNDGAESAMFKQLFQKWSVKDQTMGLGKT 358
Query: 360 YVTEKVAQIKQIPFDASKLHSSPQMAAQHNMVDDGSGKVEIWRVENNGRIQVDQNSYGEF 419
+ K+A++ Q FD + LH+ P++AAQ MVDDG+GKVE+WR+EN + V+ YG F
Sbjct: 359 FSIGKIAKVFQDKFDVTLLHTKPEVAAQERMVDDGNGKVEVWRIENLELVPVEYQWYGFF 418
Query: 420 YGGDCYIILYTYPRG----QIIYTWQGANATRDELTTSAFLTVQLDRSLGGQAVQIRVSQ 475
YGGDCY++LYTY I+Y WQG +A++DEL SA+ V++DR G AVQ+RV
Sbjct: 419 YGGDCYLVLYTYEVNGKPHHILYIWQGRHASQDELAASAYQAVEVDRQFDGAAVQVRVRM 478
Query: 476 GKEPVHLLSLFKDKPLIIYKNGTSKKGGQAPAPPTRLFQVRRNLASITRIVEVDVDANSL 535
G EP H +++FK K L+I++ GTS+KG P PP RLFQ+ N S T+ VEV A+SL
Sbjct: 479 GTEPRHFMAIFKGK-LVIFEGGTSRKGNAEPDPPVRLFQIHGNDKSNTKAVEVPAFASSL 537
Query: 536 NSNDVFVLKLPQNSGYIWVGKGASQEEEKGAEYVASVL-KCKTLRIQEGEEPEEFWNSLG 594
NSNDVF+L+ Q Y+W GKG+S +E A+ +AS+L + EG+EP EFW+ LG
Sbjct: 538 NSNDVFLLR-TQAEHYLWYGKGSSGDERAMAKELASLLCDGSENTVAEGQEPAEFWDLLG 596
Query: 595 GKKDYQTSPLLETQAEDHPPRLYGCSNKTGRFVIEEIPGEFTQDDLAEDDVMLLDAWEQI 654
GK Y L+ + D RL+ CSNKTG+FV+ EI +FTQDDL DVMLLD W+Q+
Sbjct: 597 GKTPYANDKRLQQEILDVQSRLFECSNKTGQFVVTEIT-DFTQDDLNPTDVMLLDTWDQV 655
Query: 655 FIWIGKDANEVEKKESLKSAKMYLETDPSGRDKRTPIVIIKQGHEPPTFTGWFLGWDSSK 714
F+WIG +AN EK+ +L +A+ YL T PSGRD TPI+IIKQG EPP FTGWFL WD +
Sbjct: 656 FLWIGAEANATEKESALATAQQYLHTHPSGRDPDTPILIIKQGFEPPIFTGWFLAWDPNI 715
Query: 715 W 715
W
Sbjct: 716 W 716
>gi|194394237 villin 1 [Homo sapiens]
Length = 827
Score = 668 bits (1724), Expect = 0.0
Identities = 341/709 (48%), Positives = 468/709 (66%), Gaps = 18/709 (2%)
Query: 18 GLQVWRIEKLELVPVPQSAHGDFYVGDAYLVLHTAKTSRGFTYHLHFWLGKECSQDESTA 77
GLQ+WRIE +++VPVP S G F+ GD Y++L KT+ +Y +H+W+G++ S DE A
Sbjct: 18 GLQIWRIEAMQMVPVPSSTFGSFFDGDCYIILAIHKTASSLSYDIHYWIGQDSSLDEQGA 77
Query: 78 AAIFTVQMDDYLGGKPVQNRELQGYESNDFVSYFKGGLKYKAGGVASGLNHVLTNDLTAK 137
AAI+T QMDD+L G+ VQ+RE+QG ES F YFK GL + GGVASG+ HV TN +
Sbjct: 78 AAIYTTQMDDFLKGRAVQHREVQGNESEAFRGYFKQGLVIRKGGVASGMKHVETNSYDVQ 137
Query: 138 RLLHVKGRRVVRATEVPLSWDSFNKGDCFIIDLGTEIYQWCGSSCNKYERLKANQVATGI 197
RLLHVKG+R V A EV +SW SFN+GD F++DLG I QW G + ERL+ +A I
Sbjct: 138 RLLHVKGKRNVVAGEVEMSWKSFNRGDVFLLDLGKLIIQWNGPESTRMERLRGMTLAKEI 197
Query: 198 RYNERKGRSELIVVEEGSEPSE------LIKVLGEKPELPDGGDDDDIIADISNRKMAKL 251
R ER GR+ + VV+ +E + + VLG++ EL D + + + + KL
Sbjct: 198 RDQERGGRTYVGVVDGENELASPKLMEVMNHVLGKRRELK--AAVPDTVVEPALKAALKL 255
Query: 252 YMVSDASGSMRVTVVAEENPFSMAMLLSEECFILDHGAAKQIFVWKGKDANPQERKAAMK 311
Y VSD+ G++ V VA P + +L E+C+ILD G K I+VWKGK AN QE+K AM
Sbjct: 256 YHVSDSEGNLVVREVA-TRPLTQDLLSHEDCYILDQGGLK-IYVWKGKKANEQEKKGAMS 313
Query: 312 TAEEFLQQMNYSKNTQIQVLPEGGETPIFKQFFKDWRDKDQSDGFGKVYVTEKVAQIKQI 371
A F++ Y +TQ++V +G E+ +F+Q F+ W +++ G GK + VA+++Q+
Sbjct: 314 HALNFIKAKQYPPSTQVEVQNDGAESAVFQQLFQKWTASNRTSGLGKTHTVGSVAKVEQV 373
Query: 372 PFDASKLHSSPQMAAQHNMVDDGSGKVEIWRVENNGRIQVDQNSYGEFYGGDCYIILYTY 431
FDA+ +H PQ+AAQ MVDDGSG+V++WR+EN + VD G FYGGDCY++LYTY
Sbjct: 374 KFDATSMHVKPQVAAQQKMVDDGSGEVQVWRIENLELVPVDSKWLGHFYGGDCYLLLYTY 433
Query: 432 PRGQ----IIYTWQGANATRDELTTSAFLTVQLDRSLGGQAVQIRVSQGKEPVHLLSLFK 487
G+ ++Y WQG+ A++DE+T SA+ V LD+ G+ VQIRV GKEP HL+S+FK
Sbjct: 434 LIGEKQHYLLYVWQGSQASQDEITASAYQAVILDQKYNGEPVQIRVPMGKEPPHLMSIFK 493
Query: 488 DKPLIIYKNGTSKKGGQAPAPPTRLFQVRRNLASITRIVEVDVDANSLNSNDVFVLKLPQ 547
+ +++Y+ GTS+ P TRLFQV+ A+ T+ EV AN LNSNDVFVLK Q
Sbjct: 494 GR-MVVYQGGTSRTNNLETGPSTRLFQVQGTGANNTKAFEVPARANFLNSNDVFVLK-TQ 551
Query: 548 NSGYIWVGKGASQEEEKGAEYVA-SVLKCKTLRIQEGEEPEEFWNSLGGKKDYQTSPLLE 606
+ Y+W GKG S +E + A+ VA ++ + + + EG+EP FW +LGGK Y + L+
Sbjct: 552 SCCYLWCGKGCSGDEREMAKMVADTISRTEKQVVVEGQEPANFWMALGGKAPYANTKRLQ 611
Query: 607 TQAEDHPPRLYGCSNKTGRFVIEEIPGEFTQDDLAEDDVMLLDAWEQIFIWIGKDANEVE 666
+ PRL+ CSNKTGRF+ EIP +F QDDL EDDV LLD W+Q+F WIGK ANE E
Sbjct: 612 EENLVITPRLFECSNKTGRFLATEIP-DFNQDDLEEDDVFLLDVWDQVFFWIGKHANEEE 670
Query: 667 KKESLKSAKMYLETDPSGRDKRTPIVIIKQGHEPPTFTGWFLGWDSSKW 715
KK + +A+ YL+T PSGRD TPI+++KQGHEPPTFTGWFL WD KW
Sbjct: 671 KKAAATTAQEYLKTHPSGRDPETPIIVVKQGHEPPTFTGWFLAWDPFKW 719
>gi|94721268 villin-like protein [Homo sapiens]
Length = 856
Score = 505 bits (1300), Expect = e-143
Identities = 281/715 (39%), Positives = 426/715 (59%), Gaps = 26/715 (3%)
Query: 14 GKQAGLQVWRIEKLELVPVPQSAHGDFYVGDAYLVLH---TAKTSRGFTYHLHFWLGKEC 70
G Q GL +W E ++VPVP+ A+G+F+ Y++LH + K ++G + LH+W+GK+
Sbjct: 9 GMQGGLHIWISENRKMVPVPEGAYGNFFEEHCYVILHVPQSPKATQGASSDLHYWVGKQA 68
Query: 71 SQDESTAAAIFTVQMDDYLGGKPVQNRELQGYESNDFVSYFKGGLKYKAGGVASGLNHVL 130
+ AA F ++ D LGG+ V +RE QG+ES+ F SYF+ G+ Y+ GG+AS L HV
Sbjct: 69 GAEAQGAAEAFQQRLQDELGGQTVLHREAQGHESDCFCSYFRPGIIYRKGGLASDLKHVE 128
Query: 131 TNDLTAKRLLHVKGRRVVRATEVPLSWDSFNKGDCFIIDLGTEIYQWCGSSCNKYERLKA 190
TN +RLLH+KGR+ V ATEV LSW+SFNKGD F++DLG + QW G + E+ +
Sbjct: 129 TNLFNIQRLLHIKGRKHVSATEVELSWNSFNKGDIFLLDLGKMMIQWNGPKTSISEKARG 188
Query: 191 NQVATGIRYNER-KGRSELIVVEEGSEPSELIK----VLGEKPELPDGGDDDDIIADISN 245
+ +R ER GR+++ VV++ ++ +L++ VLG + I +
Sbjct: 189 LALTYSLRDRERGGGRAQIGVVDDEAKAPDLMQIMEAVLGRRVGSLRAATPSKDINQLQK 248
Query: 246 RKMAKLYMVSDASGSMRVTVVAEENPFSMAMLLSEECFILDHGAAKQIFVWKGKDANPQE 305
+ +LY V + + V +A P + +L E+ +ILD G K I+VW+G+ ++ QE
Sbjct: 249 ANV-RLYHVYEKGKDLVVLELATP-PLTQDLLQEEDFYILDQGGFK-IYVWQGRMSSLQE 305
Query: 306 RKAAMKTAEEFLQQMNYSKNTQIQVLPEGGETPIFKQFFKDWRDKDQSDGFGKVYVTEKV 365
RKAA A F+Q Y T ++V+ +G E+ FKQ F+ W +K + + K+ +K
Sbjct: 306 RKAAFSRAVGFIQAKGYPTYTNVEVVNDGAESAAFKQLFRTWSEKRRRN--QKLGGRDKS 363
Query: 366 AQIKQIPFDASKLHSSPQMAAQHNMVDDGSGKVEIWRVENNGRIQVDQNSYGEFYGGDCY 425
+K D KLH+ P++AAQ MVDDGSGKVE+W +++ R VD +G+ G+CY
Sbjct: 364 IHVK---LDVGKLHTQPKLAAQLRMVDDGSGKVEVWCIQDLHRQPVDPKRHGQLCAGNCY 420
Query: 426 IILYTYPR----GQIIYTWQGANATRDELTTSAFLTVQLDRSLGGQAVQIRVSQGKEPVH 481
++LYTY R I+Y WQG AT DE+ +LD GG VQ V+ G EP H
Sbjct: 421 LVLYTYQRLGRVQYILYLWQGHQATADEIEALNSNAEELDVMYGGVLVQEHVTMGSEPPH 480
Query: 482 LLSLFKDKPLIIYKNGTSKKGGQAPAPPTRLFQVRRNLASITRIVEVDVDANSLNSNDVF 541
L++F+ + L+I++ G A TRLFQV+ + TR +EV A+SLNS+D+F
Sbjct: 481 FLAIFQGQ-LVIFQERAGHHGKGQSASTTRLFQVQGTDSHNTRTMEVPARASSLNSSDIF 539
Query: 542 VLKLPQNSGYIWVGKGASQEEEKGAEYVASVLKCKTLR-IQEGEEPEEFWNSLGGKKDYQ 600
+L + + Y+W GKG + ++ + A V +V+ K + EG+EP FW +LGG+ Y
Sbjct: 540 LL-VTASVCYLWFGKGCNGDQREMARVVVTVISRKNEETVLEGQEPPHFWEALGGRAPYP 598
Query: 601 TSPLLETQAEDHPPRLYGCSNKTGRFVIEEIPGEFTQDDLAEDDVMLLDAWEQIFIWIGK 660
++ L + PRL+ CS+ G V+ E+ G F+Q+DL + D+MLLD W++IF+W+G+
Sbjct: 599 SNKRLPEEVPSFQPRLFECSSHMGCLVLAEV-GFFSQEDLDKYDIMLLDTWQEIFLWLGE 657
Query: 661 DANEVEKKESLKSAKMYLETDPSGRDKRTPIVIIKQGHEPPTFTGWFLGWDSSKW 715
A+ E KE++ + YL+T P+GR TPIV++KQGHEPPTF GWF WD KW
Sbjct: 658 AAS--EWKEAVAWGQEYLKTHPAGRSPATPIVLVKQGHEPPTFIGWFFTWDPYKW 710
>gi|63252913 gelsolin-like capping protein [Homo sapiens]
Length = 348
Score = 352 bits (902), Expect = 9e-97
Identities = 166/340 (48%), Positives = 240/340 (70%), Gaps = 4/340 (1%)
Query: 10 FARAGKQAGLQVWRIEKLELVPVPQSAHGDFYVGDAYLVLHTAKTSRGFTYHLHFWLGKE 69
F + + GL VWR+EKL+ VPV Q G F+ GD+YLVLH HLH W+G++
Sbjct: 12 FPGSVQDPGLHVWRVEKLKPVPVAQENQGVFFSGDSYLVLHNGPEE---VSHLHLWIGQQ 68
Query: 70 CSQDESTAAAIFTVQMDDYLGGKPVQNRELQGYESNDFVSYFKGGLKYKAGGVASGLNHV 129
S+DE A A+ V ++ LG +PVQ+RE+QG ES+ F+SYF GLKY+ GGV S +
Sbjct: 69 SSRDEQGACAVLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGGVESAFHKT 128
Query: 130 LTNDLTA-KRLLHVKGRRVVRATEVPLSWDSFNKGDCFIIDLGTEIYQWCGSSCNKYERL 188
T A K+L VKG++ +RATE L+WDSFN GDCFI+DLG I+ WCG N ER
Sbjct: 129 STGAPAAIKKLYQVKGKKNIRATERALNWDSFNTGDCFILDLGQNIFAWCGGKSNILERN 188
Query: 189 KANQVATGIRYNERKGRSELIVVEEGSEPSELIKVLGEKPELPDGGDDDDIIADISNRKM 248
KA +A IR +ER+G++++ +V +G EP+E+I+VLG KP L +G ++D+ AD +N +
Sbjct: 189 KARDLALAIRDSERQGKAQVEIVTDGEEPAEMIQVLGPKPALKEGNPEEDLTADKANAQA 248
Query: 249 AKLYMVSDASGSMRVTVVAEENPFSMAMLLSEECFILDHGAAKQIFVWKGKDANPQERKA 308
A LY VSDA+G M +T VA+ +PF++ +L+S++CF+LD+G +I++WKG+ AN +ER+A
Sbjct: 249 AALYKVSDATGQMNLTKVADSSPFALELLISDDCFVLDNGLCGKIYIWKGRKANEKERQA 308
Query: 309 AMKTAEEFLQQMNYSKNTQIQVLPEGGETPIFKQFFKDWR 348
A++ AE F+ +M Y+ NTQ+++LP+G E+PIFKQFFKDW+
Sbjct: 309 ALQVAEGFISRMQYAPNTQVEILPQGHESPIFKQFFKDWK 348
Score = 118 bits (295), Expect = 2e-26
Identities = 99/335 (29%), Positives = 155/335 (46%), Gaps = 30/335 (8%)
Query: 398 VEIWRVENNGRIQVDQNSYGEFYGGDCYIILYTYPRG-QIIYTWQGANATRDELTTSAFL 456
+ +WRVE + V Q + G F+ GD Y++L+ P ++ W G ++RDE A L
Sbjct: 21 LHVWRVEKLKPVPVAQENQGVFFSGDSYLVLHNGPEEVSHLHLWIGQQSSRDEQGACAVL 80
Query: 457 TVQLDRSLGGQAVQIRVSQGKEPVHLLSLFKDKPLIIYKNGTS----KKGGQAPAPPTRL 512
V L+ LG + VQ R QG E +S F + L + G K APA +L
Sbjct: 81 AVHLNTLLGERPVQHREVQGNESDLFMSYF-PRGLKYQEGGVESAFHKTSTGAPAAIKKL 139
Query: 513 FQV--RRNLASITRIVEVDVDANSLNSNDVFVLKLPQNSGYIWVGKGASQEEEKGAEYVA 570
+QV ++N+ + R + D S N+ D F+L L QN + W G ++ E A +A
Sbjct: 140 YQVKGKKNIRATERALNWD----SFNTGDCFILDLGQNI-FAWCGGKSNILERNKARDLA 194
Query: 571 SVL-------KCKTLRIQEGEEPEEFWNSLGG----KKDYQTSPLLETQAEDHPPRLYGC 619
+ K + + +GEEP E LG K+ L +A LY
Sbjct: 195 LAIRDSERQGKAQVEIVTDGEEPAEMIQVLGPKPALKEGNPEEDLTADKANAQAAALYKV 254
Query: 620 SNKTGRFVIEEI--PGEFTQDDLAEDDVMLLD--AWEQIFIWIGKDANEVEKKESLKSAK 675
S+ TG+ + ++ F + L DD +LD +I+IW G+ ANE E++ +L+ A+
Sbjct: 255 SDATGQMNLTKVADSSPFALELLISDDCFVLDNGLCGKIYIWKGRKANEKERQAALQVAE 314
Query: 676 MYLETDPSGRDKRTPIVIIKQGHEPPTFTGWFLGW 710
++ T + I+ QGHE P F +F W
Sbjct: 315 GFISRMQYA--PNTQVEILPQGHESPIFKQFFKDW 347
>gi|4503743 flightless I homolog [Homo sapiens]
Length = 1269
Score = 280 bits (715), Expect = 4e-75
Identities = 229/797 (28%), Positives = 368/797 (46%), Gaps = 110/797 (13%)
Query: 6 YHEEFAR-AGKQAGLQVWRIEKLELVPVPQSAHGDFYVGDAYLVLHTAKTSRG-FTYHLH 63
Y E F G+ GL +W+IE V V ++ HG FY D Y+VL T G + ++
Sbjct: 487 YSEFFTEDVGQLPGLTIWQIENFVPVLVEEAFHGKFYEADCYIVLKTFLDDSGSLNWEIY 546
Query: 64 FWLGKECSQDESTAAAIFTVQMDDYLGGKPVQNRELQGYESNDFVSYFKGGLKYKAGGVA 123
+W+G E + D+ +AI V + +YLG + RE G ES +F+ F + Y GG A
Sbjct: 547 YWIGGEATLDKKACSAIHAVNLRNYLGAECRTVREEMGDESEEFLQVFDNDISYIEGGTA 606
Query: 124 SGLNHVLTNDLTAKRLLHVKGRRVVRATEVPLSWDSFNKGDCFIIDLGTEIYQWCGSSCN 183
SG + + + R+ V G++ ++ VPL S + F++D G +IY W G+
Sbjct: 607 SGF-YTVEDTHYVTRMYRVYGKKNIKLEPVPLKGTSLDPRFVFLLDRGLDIYVWRGAQAT 665
Query: 184 KYERLKANQVATGIRYNERKGRSELIVVEEGSEPSELIKVLGEKPELPDGGDDDDIIADI 243
KA A I NERKG++E+ ++ +G E E + LG +P +D
Sbjct: 666 LSSTTKARLFAEKINKNERKGKAEITLLVQGQELPEFWEALGGEPSEIKKHVPEDFWP-- 723
Query: 244 SNRKMAKLYMVSDASG-------SMRVTVVAEENPFSMAM--------LLSEEC-FILDH 287
KLY V G + +++V ++ P M LL C +ILD
Sbjct: 724 ---PQPKLYKVGLGLGYLELPQINYKLSVEHKQRPKVELMPRMRLLQSLLDTRCVYILD- 779
Query: 288 GAAKQIFVWKGKDANPQERKAAMKTAEEFLQQMNYSKNTQIQVLPEGGETPIFKQFFKDW 347
+F+W G+ + R AA+K +E ++ ++ + EG E +FK FK+W
Sbjct: 780 -CWSDVFIWLGRKSPRLVRAAALKLGQELCGMLHRPRHATVSRSLEGTEAQVFKAKFKNW 838
Query: 348 RD------------KDQSDGF-GKV-YVTEKVAQIKQ------IPFD-ASKLHSSPQMAA 386
D QS G GKV EK Q+K +P L + Q+
Sbjct: 839 DDVLTVDYTRNAEAVLQSPGLSGKVKRDAEKKDQMKADLTALFLPRQPPMSLAEAEQLME 898
Query: 387 QHNMVDDGSGKVEIWRVENNGRIQVDQNSYGEFYGGDCYIILYTY--------------- 431
+ N DG +E + +E ++ + +G FY DCY+ L Y
Sbjct: 899 EWNEDLDG---MEGFVLEGKKFARLPEEEFGHFYTQDCYVFLCRYWVPVEYEEEEKKEDK 955
Query: 432 ------PRGQ-----------------IIYTWQGANATRDELTTSAF-LTVQLDRSLGGQ 467
G+ I+Y WQG A+ T F L + + G+
Sbjct: 956 EEKAEGKEGEEATAEAEEKQPEEDFQCIVYFWQGREASNMGWLTFTFSLQKKFESLFPGK 1015
Query: 468 AVQIRVSQGKEPVHLLSLFKDKPLIIYKNGTSKKGGQAPAPPTRLFQVRRNLASI-TRIV 526
+R++Q +E LS FK K +I + +G Q P+ L+Q+R N +++ TR +
Sbjct: 1016 LEVVRMTQQQENPKFLSHFKRKFIIHRGKRKAVQGAQQPS----LYQIRTNGSALCTRCI 1071
Query: 527 EVDVDANSLNSNDVFVLKLP----QNSG--YIWVGKGASQEEEKGAEYVASVL---KCKT 577
+++ D++ LNS F+LK+P N G Y WVG+ + +E K AE + + +
Sbjct: 1072 QINTDSSLLNSEFCFILKVPFESEDNQGIVYAWVGRASDPDEAKLAEDILNTMFDTSYSK 1131
Query: 578 LRIQEGEEPEE-FWNSLGGKKDYQTSPLLETQAEDHPPRLYGCSNKTGRFVIEEIPGEFT 636
I EGEEPE FW +G +K Y + + H RL+ CSN+ G F + E +F
Sbjct: 1132 QVINEGEEPENFFWVGIGAQKPYDD----DAEYMKH-TRLFRCSNEKGYFAVTEKCSDFC 1186
Query: 637 QDDLAEDDVMLLDAWEQIFIWIGKDANEVEKKESLKSAKMYLETDPSGRDKR-TPIVIIK 695
QDDLA+DD+MLLD +++++W+G ++VE K SLK+ ++Y++ S +R + +++
Sbjct: 1187 QDDLADDDIMLLDNGQEVYMWVGTQTSQVEIKLSLKACQVYIQHMRSKEHERPRRLRLVR 1246
Query: 696 QGHEPPTFTGWFLGWDS 712
+G+E FT F W +
Sbjct: 1247 KGNEQHAFTRCFHAWSA 1263
>gi|150417973 supervillin isoform 2 [Homo sapiens]
Length = 2214
Score = 135 bits (339), Expect = 2e-31
Identities = 160/703 (22%), Positives = 293/703 (41%), Gaps = 154/703 (21%)
Query: 139 LLHVKGRRVVRATEVPLSWDSFNKGDCFIIDLGTEIYQWCGSSCNKYERLKANQVATGIR 198
LL +KGRR V+ V + N GDCF++ + W G N E+ KA+++AT I+
Sbjct: 1445 LLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQ 1504
Query: 199 YNERKG--RSELIVVEEG-----SEPSELIKVLGEKPELPDGGD-DDDIIADISNRKMAK 250
G + + +EEG + K+LG + GD +D + + + +
Sbjct: 1505 TKRELGCRATYIQTIEEGINTHTHAAKDFWKLLGGQTSYQSAGDPKEDELYEAAIIETNC 1564
Query: 251 LYMVSDASGSMRVTVVAEENPF----SMAMLLSEECFILDHGAAKQIFVWKGKDANPQER 306
+Y + D +V +++ + ++L +E + D G+ +++VW GK+ +R
Sbjct: 1565 IYRLMDDK------LVPDDDYWGKIPKCSLLQPKEVLVFDFGS--EVYVWHGKEVTLAQR 1616
Query: 307 KAAMKTAEEFLQQMNYSKNTQIQVLPEG-------------------------GETPIFK 341
K A + A+ +N I L G ET +FK
Sbjct: 1617 KIAFQLAKHLWNGTFDYENCDINPLDPGECNPLIPRKGQGRPDWAIFGRLTEHNETILFK 1676
Query: 342 QFFKDWRDKDQSDGFGKVYVTEKVAQIKQIP------FDASKLHSSPQMAA--------- 386
+ F DW + +S+ ++AQ K+ P +D +++ S PQ A
Sbjct: 1677 EKFLDWTELKRSNEKN----PGELAQHKEDPRTDVKAYDVTRMVSMPQTTAGTILDGVNV 1732
Query: 387 ----------QHNMVDDGSGKVEIWRVENNGRIQVDQNSYGEFYGGDCYIILYTY----- 431
+ S V++W + ++ + S G+F+ GD Y++ + +
Sbjct: 1733 GRGYGLVEGHDRRQFEITSVSVDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTA 1792
Query: 432 ----PRGQ-----------IIYTWQGANATRDELTTSAFLTVQLDRSLGGQAVQIRVSQG 476
+G+ + + WQG ++T E TSA +TV+LD G Q++V QG
Sbjct: 1793 VGSRQKGEHSVRAAGKEKCVYFFWQGRHSTVSEKGTSALMTVELDEERG---AQVQVLQG 1849
Query: 477 KEPVHLLSLFKDKPLIIYKNGTSKKGGQAPAPPTRLFQVRRNLASITRIVEVDVDANSLN 536
KEP L F+ ++ +G ++ + RL+ VR + ++EV +SL
Sbjct: 1850 KEPPCFLQCFQGG--MVVHSGRREEEEENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLR 1907
Query: 537 S-NDVFVLKLPQNSGYIW-----------VGKGASQEEEKGAEYVASVLKCKTLRI---Q 581
S + VL + + Y+W VG+ A+ + ++ A + + I
Sbjct: 1908 SRTSMVVLNVNKALIYLWHGCKAQAHTKEVGRTAANKIKEQCPLEAGLHSSSKVTIHECD 1967
Query: 582 EGEEPEEFWNSLG--GKKDYQTSPLLETQAEDHPPRLYGCSNKTGRF------------- 626
EG EP FW++LG +K Y L + + + PRL+ S+ +G F
Sbjct: 1968 EGSEPLGFWDALGRRDRKAYDCM-LQDPGSFNFAPRLFILSSSSGDFAATEFVYPARAPS 2026
Query: 627 VIEEIPGEFTQDDL---AEDDVMLLDAWEQIFIWIG--KDANEV----------EKKESL 671
V+ +P F Q+DL + + L+D ++++W G N++ ++K ++
Sbjct: 2027 VVSSMP--FLQEDLYSAPQPALFLVDNHHEVYLWQGWWPIENKITGSARIRWASDRKSAM 2084
Query: 672 KSAKMYLETDPSGRDKRTPI---VIIKQGHEPPTFTGWFLGWD 711
++ Y + G++ + P +I G EP TFT F W+
Sbjct: 2085 ETVLQYCK----GKNLKKPAPKSYLIHAGLEPLTFTNMFPSWE 2123
Score = 64.7 bits (156), Expect = 3e-10
Identities = 91/387 (23%), Positives = 150/387 (38%), Gaps = 68/387 (17%)
Query: 19 LQVWRIEKLELVPVPQSAHGDFYVGDAYLV-----LHTAKTSRGFTYH-----------L 62
+ VW I + + +P+ + G F+ GDAY+V + TA SR H
Sbjct: 1754 VDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGSRQKGEHSVRAAGKEKCVY 1813
Query: 63 HFWLGKECSQDESTAAAIFTVQMDDYLGGKPVQNRELQGYESNDFVSYFKGGLKYKAGGV 122
FW G+ + E +A+ TV++D+ G Q + LQG E F+ F+GG+ +G
Sbjct: 1814 FFWQGRHSTVSEKGTSALMTVELDEERG---AQVQVLQGKEPPCFLQCFQGGMVVHSGRR 1870
Query: 123 ASGLNHVLTNDLTAKRLLHVKGRRVVRAT--EVPLSWDSFNKGDCFIIDLGTE---IYQW 177
+V + RL V+G V EV S ++ L IY W
Sbjct: 1871 EEEEENVQSE----WRLYCVRGEVPVEGNLLEVACHCSSLRSRTSMVV-LNVNKALIYLW 1925
Query: 178 CGSSCNKYE----RLKANQVATGIRYNERKGRSELIVV---EEGSEPSELIKVLGEKPEL 230
G + R AN++ S + + +EGSEP LG +
Sbjct: 1926 HGCKAQAHTKEVGRTAANKIKEQCPLEAGLHSSSKVTIHECDEGSEPLGFWDALGRR--- 1982
Query: 231 PDGGDDDDIIADISNRKMA-KLYMVSDASGSM---------RVTVVAEENPFSMAMLLS- 279
D D ++ D + A +L+++S +SG R V PF L S
Sbjct: 1983 -DRKAYDCMLQDPGSFNFAPRLFILSSSSGDFAATEFVYPARAPSVVSSMPFLQEDLYSA 2041
Query: 280 --EECFILDHGAAKQIFVWKG------------KDANPQERKAAMKTAEEFLQQMNYSKN 325
F++D+ ++++W+G + +RK+AM+T ++ + N K
Sbjct: 2042 PQPALFLVDN--HHEVYLWQGWWPIENKITGSARIRWASDRKSAMETVLQYCKGKNLKKP 2099
Query: 326 TQIQVLPEGGETPI-FKQFFKDWRDKD 351
L G P+ F F W ++
Sbjct: 2100 APKSYLIHAGLEPLTFTNMFPSWEHRE 2126
>gi|150417971 supervillin isoform 1 [Homo sapiens]
Length = 1788
Score = 135 bits (339), Expect = 2e-31
Identities = 160/703 (22%), Positives = 293/703 (41%), Gaps = 154/703 (21%)
Query: 139 LLHVKGRRVVRATEVPLSWDSFNKGDCFIIDLGTEIYQWCGSSCNKYERLKANQVATGIR 198
LL +KGRR V+ V + N GDCF++ + W G N E+ KA+++AT I+
Sbjct: 1019 LLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQ 1078
Query: 199 YNERKG--RSELIVVEEG-----SEPSELIKVLGEKPELPDGGD-DDDIIADISNRKMAK 250
G + + +EEG + K+LG + GD +D + + + +
Sbjct: 1079 TKRELGCRATYIQTIEEGINTHTHAAKDFWKLLGGQTSYQSAGDPKEDELYEAAIIETNC 1138
Query: 251 LYMVSDASGSMRVTVVAEENPF----SMAMLLSEECFILDHGAAKQIFVWKGKDANPQER 306
+Y + D +V +++ + ++L +E + D G+ +++VW GK+ +R
Sbjct: 1139 IYRLMDDK------LVPDDDYWGKIPKCSLLQPKEVLVFDFGS--EVYVWHGKEVTLAQR 1190
Query: 307 KAAMKTAEEFLQQMNYSKNTQIQVLPEG-------------------------GETPIFK 341
K A + A+ +N I L G ET +FK
Sbjct: 1191 KIAFQLAKHLWNGTFDYENCDINPLDPGECNPLIPRKGQGRPDWAIFGRLTEHNETILFK 1250
Query: 342 QFFKDWRDKDQSDGFGKVYVTEKVAQIKQIP------FDASKLHSSPQMAA--------- 386
+ F DW + +S+ ++AQ K+ P +D +++ S PQ A
Sbjct: 1251 EKFLDWTELKRSNEKN----PGELAQHKEDPRTDVKAYDVTRMVSMPQTTAGTILDGVNV 1306
Query: 387 ----------QHNMVDDGSGKVEIWRVENNGRIQVDQNSYGEFYGGDCYIILYTY----- 431
+ S V++W + ++ + S G+F+ GD Y++ + +
Sbjct: 1307 GRGYGLVEGHDRRQFEITSVSVDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTA 1366
Query: 432 ----PRGQ-----------IIYTWQGANATRDELTTSAFLTVQLDRSLGGQAVQIRVSQG 476
+G+ + + WQG ++T E TSA +TV+LD G Q++V QG
Sbjct: 1367 VGSRQKGEHSVRAAGKEKCVYFFWQGRHSTVSEKGTSALMTVELDEERG---AQVQVLQG 1423
Query: 477 KEPVHLLSLFKDKPLIIYKNGTSKKGGQAPAPPTRLFQVRRNLASITRIVEVDVDANSLN 536
KEP L F+ ++ +G ++ + RL+ VR + ++EV +SL
Sbjct: 1424 KEPPCFLQCFQGG--MVVHSGRREEEEENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLR 1481
Query: 537 S-NDVFVLKLPQNSGYIW-----------VGKGASQEEEKGAEYVASVLKCKTLRI---Q 581
S + VL + + Y+W VG+ A+ + ++ A + + I
Sbjct: 1482 SRTSMVVLNVNKALIYLWHGCKAQAHTKEVGRTAANKIKEQCPLEAGLHSSSKVTIHECD 1541
Query: 582 EGEEPEEFWNSLG--GKKDYQTSPLLETQAEDHPPRLYGCSNKTGRF------------- 626
EG EP FW++LG +K Y L + + + PRL+ S+ +G F
Sbjct: 1542 EGSEPLGFWDALGRRDRKAYDCM-LQDPGSFNFAPRLFILSSSSGDFAATEFVYPARAPS 1600
Query: 627 VIEEIPGEFTQDDL---AEDDVMLLDAWEQIFIWIG--KDANEV----------EKKESL 671
V+ +P F Q+DL + + L+D ++++W G N++ ++K ++
Sbjct: 1601 VVSSMP--FLQEDLYSAPQPALFLVDNHHEVYLWQGWWPIENKITGSARIRWASDRKSAM 1658
Query: 672 KSAKMYLETDPSGRDKRTPI---VIIKQGHEPPTFTGWFLGWD 711
++ Y + G++ + P +I G EP TFT F W+
Sbjct: 1659 ETVLQYCK----GKNLKKPAPKSYLIHAGLEPLTFTNMFPSWE 1697
Score = 64.7 bits (156), Expect = 3e-10
Identities = 91/387 (23%), Positives = 150/387 (38%), Gaps = 68/387 (17%)
Query: 19 LQVWRIEKLELVPVPQSAHGDFYVGDAYLV-----LHTAKTSRGFTYH-----------L 62
+ VW I + + +P+ + G F+ GDAY+V + TA SR H
Sbjct: 1328 VDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGSRQKGEHSVRAAGKEKCVY 1387
Query: 63 HFWLGKECSQDESTAAAIFTVQMDDYLGGKPVQNRELQGYESNDFVSYFKGGLKYKAGGV 122
FW G+ + E +A+ TV++D+ G Q + LQG E F+ F+GG+ +G
Sbjct: 1388 FFWQGRHSTVSEKGTSALMTVELDEERG---AQVQVLQGKEPPCFLQCFQGGMVVHSGRR 1444
Query: 123 ASGLNHVLTNDLTAKRLLHVKGRRVVRAT--EVPLSWDSFNKGDCFIIDLGTE---IYQW 177
+V + RL V+G V EV S ++ L IY W
Sbjct: 1445 EEEEENVQSE----WRLYCVRGEVPVEGNLLEVACHCSSLRSRTSMVV-LNVNKALIYLW 1499
Query: 178 CGSSCNKYE----RLKANQVATGIRYNERKGRSELIVV---EEGSEPSELIKVLGEKPEL 230
G + R AN++ S + + +EGSEP LG +
Sbjct: 1500 HGCKAQAHTKEVGRTAANKIKEQCPLEAGLHSSSKVTIHECDEGSEPLGFWDALGRR--- 1556
Query: 231 PDGGDDDDIIADISNRKMA-KLYMVSDASGSM---------RVTVVAEENPFSMAMLLS- 279
D D ++ D + A +L+++S +SG R V PF L S
Sbjct: 1557 -DRKAYDCMLQDPGSFNFAPRLFILSSSSGDFAATEFVYPARAPSVVSSMPFLQEDLYSA 1615
Query: 280 --EECFILDHGAAKQIFVWKG------------KDANPQERKAAMKTAEEFLQQMNYSKN 325
F++D+ ++++W+G + +RK+AM+T ++ + N K
Sbjct: 1616 PQPALFLVDN--HHEVYLWQGWWPIENKITGSARIRWASDRKSAMETVLQYCKGKNLKKP 1673
Query: 326 TQIQVLPEGGETPI-FKQFFKDWRDKD 351
L G P+ F F W ++
Sbjct: 1674 APKSYLIHAGLEPLTFTNMFPSWEHRE 1700
>gi|41872646 cullin 7 [Homo sapiens]
Length = 1698
Score = 31.2 bits (69), Expect = 3.5
Identities = 26/83 (31%), Positives = 35/83 (42%), Gaps = 1/83 (1%)
Query: 506 PAPPTRLFQVRRNLASITRIVEVDVDANSLNSNDVFVLKLPQNSGYIWVGKGASQEEEKG 565
P P RL Q S ++ ++ L D +LKL I VG GAS +E K
Sbjct: 1294 PCFPNRLPQQMLQSLSTSKELQRQFHVYQLQQLDQELLKLEDTEKKIQVGLGASGKEHK- 1352
Query: 566 AEYVASVLKCKTLRIQEGEEPEE 588
+E + + EGEE EE
Sbjct: 1353 SEKEEEAGAAAVVDVAEGEEEEE 1375
>gi|112382214 SEC24 (S. cerevisiae) homolog B isoform b [Homo sapiens]
Length = 1233
Score = 31.2 bits (69), Expect = 3.5
Identities = 15/50 (30%), Positives = 24/50 (48%)
Query: 134 LTAKRLLHVKGRRVVRATEVPLSWDSFNKGDCFIIDLGTEIYQWCGSSCN 183
LT + +HV R V + LS + + F++D G+ Y W G C+
Sbjct: 1092 LTDEGAVHVNDRIVPQPPLQKLSAEKLTREGAFLMDCGSVFYIWVGKGCD 1141
>gi|112382212 SEC24 (S. cerevisiae) homolog B isoform a [Homo sapiens]
Length = 1268
Score = 31.2 bits (69), Expect = 3.5
Identities = 15/50 (30%), Positives = 24/50 (48%)
Query: 134 LTAKRLLHVKGRRVVRATEVPLSWDSFNKGDCFIIDLGTEIYQWCGSSCN 183
LT + +HV R V + LS + + F++D G+ Y W G C+
Sbjct: 1127 LTDEGAVHVNDRIVPQPPLQKLSAEKLTREGAFLMDCGSVFYIWVGKGCD 1176
>gi|115583667 sodium channel, voltage-gated, type XI, alpha [Homo
sapiens]
Length = 1791
Score = 30.4 bits (67), Expect = 6.0
Identities = 20/81 (24%), Positives = 36/81 (44%), Gaps = 3/81 (3%)
Query: 149 RATEVPLSWDSFNKGDCFIIDLGTEIYQWCGSSCNKYERLKANQVATGIRYNERKGRSEL 208
R T+V L+ D F + CF+ + +C C K + +VA G + +
Sbjct: 828 RKTKVQLALDRFRRAFCFV---RHTLEHFCHKWCRKQNLPQQKEVAGGCAAQSKDIIPLV 884
Query: 209 IVVEEGSEPSELIKVLGEKPE 229
+ ++ GSE E + +L P+
Sbjct: 885 MEMKRGSETQEELGILTSVPK 905
>gi|52317263 olfactory receptor, family 4, subfamily N, member 2
[Homo sapiens]
Length = 307
Score = 30.4 bits (67), Expect = 6.0
Identities = 19/69 (27%), Positives = 34/69 (49%), Gaps = 2/69 (2%)
Query: 46 YLVLHTAKTSRGFTYHLHFWLGKECSQDESTAAAIFTVQMDDYLGGKPVQNRELQGYESN 105
+L++ T K+ G T L+F+LG D S + + + D+L K + + +G +
Sbjct: 43 FLIIFTIKSDPGLTAPLYFFLGNLAFLDASYSFIVAPRMLVDFLSAKKIIS--YRGCITQ 100
Query: 106 DFVSYFKGG 114
F +F GG
Sbjct: 101 LFFLHFLGG 109
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.134 0.402
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,157,370
Number of Sequences: 37866
Number of extensions: 1270441
Number of successful extensions: 3013
Number of sequences better than 10.0: 22
Number of HSP's better than 10.0 without gapping: 19
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 2656
Number of HSP's gapped (non-prelim): 36
length of query: 715
length of database: 18,247,518
effective HSP length: 109
effective length of query: 606
effective length of database: 14,120,124
effective search space: 8556795144
effective search space used: 8556795144
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.