BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|15991827 hexokinase 1 isoform HKI-R [Homo sapiens] (916 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|15991827 hexokinase 1 isoform HKI-R [Homo sapiens] 1832 0.0 gi|15991829 hexokinase 1 isoform HKI-ta/tb [Homo sapiens] 1788 0.0 gi|15991831 hexokinase 1 isoform HKI-ta/tb [Homo sapiens] 1788 0.0 gi|188497750 hexokinase 1 isoform HKI-td [Homo sapiens] 1788 0.0 gi|188497754 hexokinase 1 isoform HKI [Homo sapiens] 1788 0.0 gi|15553127 hexokinase 2 [Homo sapiens] 1368 0.0 gi|156151420 hexokinase domain containing 1 [Homo sapiens] 1323 0.0 gi|194097330 hexokinase 3 [Homo sapiens] 944 0.0 gi|15967161 glucokinase isoform 3 [Homo sapiens] 506 e-143 gi|4503951 glucokinase isoform 1 [Homo sapiens] 504 e-142 gi|15967159 glucokinase isoform 2 [Homo sapiens] 503 e-142 gi|164663810 ribosomal modification protein rimK-like family mem... 35 0.42 gi|134254462 ribosomal modification protein rimK-like family mem... 33 0.93 gi|21389509 KPL2 protein isoform 2 [Homo sapiens] 32 2.7 gi|145699133 KPL2 protein isoform 1 [Homo sapiens] 32 2.7 gi|42415492 chromosome 14 open reading frame 106 [Homo sapiens] 30 7.9 >gi|15991827 hexokinase 1 isoform HKI-R [Homo sapiens] Length = 916 Score = 1832 bits (4746), Expect = 0.0 Identities = 916/916 (100%), Positives = 916/916 (100%) Query: 1 MDCEHSLSLPCRGAEAWEIGIDKYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTATV 60 MDCEHSLSLPCRGAEAWEIGIDKYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTATV Sbjct: 1 MDCEHSLSLPCRGAEAWEIGIDKYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTATV 60 Query: 61 KMLPTFVRSIPDGSEKGDFIALDLGGSSFRILRVQVNHEKNQNVHMESEVYDTPENIVHG 120 KMLPTFVRSIPDGSEKGDFIALDLGGSSFRILRVQVNHEKNQNVHMESEVYDTPENIVHG Sbjct: 61 KMLPTFVRSIPDGSEKGDFIALDLGGSSFRILRVQVNHEKNQNVHMESEVYDTPENIVHG 120 Query: 121 SGSQLFDHVAECLGDFMEKRKIKDKKLPVGFTFSFPCQQSKIDEAILITWTKRFKASGVE 180 SGSQLFDHVAECLGDFMEKRKIKDKKLPVGFTFSFPCQQSKIDEAILITWTKRFKASGVE Sbjct: 121 SGSQLFDHVAECLGDFMEKRKIKDKKLPVGFTFSFPCQQSKIDEAILITWTKRFKASGVE 180 Query: 181 GADVVKLLNKAIKKRGDYDANIVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYMEE 240 GADVVKLLNKAIKKRGDYDANIVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYMEE Sbjct: 181 GADVVKLLNKAIKKRGDYDANIVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYMEE 240 Query: 241 LRHIDLVEGDEGRMCINTEWGAFGDDGSLEDIRTEFDREIDRGSLNPGKQLFEKMVSGMY 300 LRHIDLVEGDEGRMCINTEWGAFGDDGSLEDIRTEFDREIDRGSLNPGKQLFEKMVSGMY Sbjct: 241 LRHIDLVEGDEGRMCINTEWGAFGDDGSLEDIRTEFDREIDRGSLNPGKQLFEKMVSGMY 300 Query: 301 LGELVRLILVKMAKEGLLFEGRITPELLTRGKFNTSDVSAIEKNKEGLHNAKEILTRLGV 360 LGELVRLILVKMAKEGLLFEGRITPELLTRGKFNTSDVSAIEKNKEGLHNAKEILTRLGV Sbjct: 301 LGELVRLILVKMAKEGLLFEGRITPELLTRGKFNTSDVSAIEKNKEGLHNAKEILTRLGV 360 Query: 361 EPSDDDCVSVQHVCTIVSFRSANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKTHP 420 EPSDDDCVSVQHVCTIVSFRSANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKTHP Sbjct: 361 EPSDDDCVSVQHVCTIVSFRSANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKTHP 420 Query: 421 QYSRRFHKTLRRLVPDSDVRFLLSESGSGKGAAMVTAVAYRLAEQHRQIEETLAHFHLTK 480 QYSRRFHKTLRRLVPDSDVRFLLSESGSGKGAAMVTAVAYRLAEQHRQIEETLAHFHLTK Sbjct: 421 QYSRRFHKTLRRLVPDSDVRFLLSESGSGKGAAMVTAVAYRLAEQHRQIEETLAHFHLTK 480 Query: 481 DMLLEVKKRMRAEMELGLRKQTHNNAVVKMLPSFVRRTPDGTENGDFLALDLGGTNFRVL 540 DMLLEVKKRMRAEMELGLRKQTHNNAVVKMLPSFVRRTPDGTENGDFLALDLGGTNFRVL Sbjct: 481 DMLLEVKKRMRAEMELGLRKQTHNNAVVKMLPSFVRRTPDGTENGDFLALDLGGTNFRVL 540 Query: 541 LVKIRSGKKRTVEMHNKIYAIPIEIMQGTGEELFDHIVSCISDFLDYMGIKGPRMPLGFT 600 LVKIRSGKKRTVEMHNKIYAIPIEIMQGTGEELFDHIVSCISDFLDYMGIKGPRMPLGFT Sbjct: 541 LVKIRSGKKRTVEMHNKIYAIPIEIMQGTGEELFDHIVSCISDFLDYMGIKGPRMPLGFT 600 Query: 601 FSFPCQQTSLDAGILITWTKGFKATDCVGHDVVTLLRDAIKRREEFDLDVVAVVNDTVGT 660 FSFPCQQTSLDAGILITWTKGFKATDCVGHDVVTLLRDAIKRREEFDLDVVAVVNDTVGT Sbjct: 601 FSFPCQQTSLDAGILITWTKGFKATDCVGHDVVTLLRDAIKRREEFDLDVVAVVNDTVGT 660 Query: 661 MMTCAYEEPTCEVGLIVGTGSNACYMEEMKNVEMVEGDQGQMCINMEWGAFGDNGCLDDI 720 MMTCAYEEPTCEVGLIVGTGSNACYMEEMKNVEMVEGDQGQMCINMEWGAFGDNGCLDDI Sbjct: 661 MMTCAYEEPTCEVGLIVGTGSNACYMEEMKNVEMVEGDQGQMCINMEWGAFGDNGCLDDI 720 Query: 721 RTHYDRLVDEYSLNAGKQRYEKMISGMYLGEIVRNILIDFTKKGFLFRGQISETLKTRGI 780 RTHYDRLVDEYSLNAGKQRYEKMISGMYLGEIVRNILIDFTKKGFLFRGQISETLKTRGI Sbjct: 721 RTHYDRLVDEYSLNAGKQRYEKMISGMYLGEIVRNILIDFTKKGFLFRGQISETLKTRGI 780 Query: 781 FETKFLSQIESDRLALLQVRAILQQLGLNSTCDDSILVKTVCGVVSRRAAQLCGAGMAAV 840 FETKFLSQIESDRLALLQVRAILQQLGLNSTCDDSILVKTVCGVVSRRAAQLCGAGMAAV Sbjct: 781 FETKFLSQIESDRLALLQVRAILQQLGLNSTCDDSILVKTVCGVVSRRAAQLCGAGMAAV 840 Query: 841 VDKIRENRGLDRLNVTVGVDGTLYKLHPHFSRIMHQTVKELSPKCNVSFLLSEDGSGKGA 900 VDKIRENRGLDRLNVTVGVDGTLYKLHPHFSRIMHQTVKELSPKCNVSFLLSEDGSGKGA Sbjct: 841 VDKIRENRGLDRLNVTVGVDGTLYKLHPHFSRIMHQTVKELSPKCNVSFLLSEDGSGKGA 900 Query: 901 ALITAVGVRLRTEASS 916 ALITAVGVRLRTEASS Sbjct: 901 ALITAVGVRLRTEASS 916 >gi|15991829 hexokinase 1 isoform HKI-ta/tb [Homo sapiens] Length = 921 Score = 1788 bits (4632), Expect = 0.0 Identities = 897/899 (99%), Positives = 897/899 (99%) Query: 18 EIGIDKYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEKG 77 E IDKYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEKG Sbjct: 23 ESEIDKYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEKG 82 Query: 78 DFIALDLGGSSFRILRVQVNHEKNQNVHMESEVYDTPENIVHGSGSQLFDHVAECLGDFM 137 DFIALDLGGSSFRILRVQVNHEKNQNVHMESEVYDTPENIVHGSGSQLFDHVAECLGDFM Sbjct: 83 DFIALDLGGSSFRILRVQVNHEKNQNVHMESEVYDTPENIVHGSGSQLFDHVAECLGDFM 142 Query: 138 EKRKIKDKKLPVGFTFSFPCQQSKIDEAILITWTKRFKASGVEGADVVKLLNKAIKKRGD 197 EKRKIKDKKLPVGFTFSFPCQQSKIDEAILITWTKRFKASGVEGADVVKLLNKAIKKRGD Sbjct: 143 EKRKIKDKKLPVGFTFSFPCQQSKIDEAILITWTKRFKASGVEGADVVKLLNKAIKKRGD 202 Query: 198 YDANIVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYMEELRHIDLVEGDEGRMCIN 257 YDANIVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYMEELRHIDLVEGDEGRMCIN Sbjct: 203 YDANIVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYMEELRHIDLVEGDEGRMCIN 262 Query: 258 TEWGAFGDDGSLEDIRTEFDREIDRGSLNPGKQLFEKMVSGMYLGELVRLILVKMAKEGL 317 TEWGAFGDDGSLEDIRTEFDREIDRGSLNPGKQLFEKMVSGMYLGELVRLILVKMAKEGL Sbjct: 263 TEWGAFGDDGSLEDIRTEFDREIDRGSLNPGKQLFEKMVSGMYLGELVRLILVKMAKEGL 322 Query: 318 LFEGRITPELLTRGKFNTSDVSAIEKNKEGLHNAKEILTRLGVEPSDDDCVSVQHVCTIV 377 LFEGRITPELLTRGKFNTSDVSAIEKNKEGLHNAKEILTRLGVEPSDDDCVSVQHVCTIV Sbjct: 323 LFEGRITPELLTRGKFNTSDVSAIEKNKEGLHNAKEILTRLGVEPSDDDCVSVQHVCTIV 382 Query: 378 SFRSANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKTHPQYSRRFHKTLRRLVPDS 437 SFRSANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKTHPQYSRRFHKTLRRLVPDS Sbjct: 383 SFRSANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKTHPQYSRRFHKTLRRLVPDS 442 Query: 438 DVRFLLSESGSGKGAAMVTAVAYRLAEQHRQIEETLAHFHLTKDMLLEVKKRMRAEMELG 497 DVRFLLSESGSGKGAAMVTAVAYRLAEQHRQIEETLAHFHLTKDMLLEVKKRMRAEMELG Sbjct: 443 DVRFLLSESGSGKGAAMVTAVAYRLAEQHRQIEETLAHFHLTKDMLLEVKKRMRAEMELG 502 Query: 498 LRKQTHNNAVVKMLPSFVRRTPDGTENGDFLALDLGGTNFRVLLVKIRSGKKRTVEMHNK 557 LRKQTHNNAVVKMLPSFVRRTPDGTENGDFLALDLGGTNFRVLLVKIRSGKKRTVEMHNK Sbjct: 503 LRKQTHNNAVVKMLPSFVRRTPDGTENGDFLALDLGGTNFRVLLVKIRSGKKRTVEMHNK 562 Query: 558 IYAIPIEIMQGTGEELFDHIVSCISDFLDYMGIKGPRMPLGFTFSFPCQQTSLDAGILIT 617 IYAIPIEIMQGTGEELFDHIVSCISDFLDYMGIKGPRMPLGFTFSFPCQQTSLDAGILIT Sbjct: 563 IYAIPIEIMQGTGEELFDHIVSCISDFLDYMGIKGPRMPLGFTFSFPCQQTSLDAGILIT 622 Query: 618 WTKGFKATDCVGHDVVTLLRDAIKRREEFDLDVVAVVNDTVGTMMTCAYEEPTCEVGLIV 677 WTKGFKATDCVGHDVVTLLRDAIKRREEFDLDVVAVVNDTVGTMMTCAYEEPTCEVGLIV Sbjct: 623 WTKGFKATDCVGHDVVTLLRDAIKRREEFDLDVVAVVNDTVGTMMTCAYEEPTCEVGLIV 682 Query: 678 GTGSNACYMEEMKNVEMVEGDQGQMCINMEWGAFGDNGCLDDIRTHYDRLVDEYSLNAGK 737 GTGSNACYMEEMKNVEMVEGDQGQMCINMEWGAFGDNGCLDDIRTHYDRLVDEYSLNAGK Sbjct: 683 GTGSNACYMEEMKNVEMVEGDQGQMCINMEWGAFGDNGCLDDIRTHYDRLVDEYSLNAGK 742 Query: 738 QRYEKMISGMYLGEIVRNILIDFTKKGFLFRGQISETLKTRGIFETKFLSQIESDRLALL 797 QRYEKMISGMYLGEIVRNILIDFTKKGFLFRGQISETLKTRGIFETKFLSQIESDRLALL Sbjct: 743 QRYEKMISGMYLGEIVRNILIDFTKKGFLFRGQISETLKTRGIFETKFLSQIESDRLALL 802 Query: 798 QVRAILQQLGLNSTCDDSILVKTVCGVVSRRAAQLCGAGMAAVVDKIRENRGLDRLNVTV 857 QVRAILQQLGLNSTCDDSILVKTVCGVVSRRAAQLCGAGMAAVVDKIRENRGLDRLNVTV Sbjct: 803 QVRAILQQLGLNSTCDDSILVKTVCGVVSRRAAQLCGAGMAAVVDKIRENRGLDRLNVTV 862 Query: 858 GVDGTLYKLHPHFSRIMHQTVKELSPKCNVSFLLSEDGSGKGAALITAVGVRLRTEASS 916 GVDGTLYKLHPHFSRIMHQTVKELSPKCNVSFLLSEDGSGKGAALITAVGVRLRTEASS Sbjct: 863 GVDGTLYKLHPHFSRIMHQTVKELSPKCNVSFLLSEDGSGKGAALITAVGVRLRTEASS 921 >gi|15991831 hexokinase 1 isoform HKI-ta/tb [Homo sapiens] Length = 921 Score = 1788 bits (4632), Expect = 0.0 Identities = 897/899 (99%), Positives = 897/899 (99%) Query: 18 EIGIDKYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEKG 77 E IDKYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEKG Sbjct: 23 ESEIDKYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEKG 82 Query: 78 DFIALDLGGSSFRILRVQVNHEKNQNVHMESEVYDTPENIVHGSGSQLFDHVAECLGDFM 137 DFIALDLGGSSFRILRVQVNHEKNQNVHMESEVYDTPENIVHGSGSQLFDHVAECLGDFM Sbjct: 83 DFIALDLGGSSFRILRVQVNHEKNQNVHMESEVYDTPENIVHGSGSQLFDHVAECLGDFM 142 Query: 138 EKRKIKDKKLPVGFTFSFPCQQSKIDEAILITWTKRFKASGVEGADVVKLLNKAIKKRGD 197 EKRKIKDKKLPVGFTFSFPCQQSKIDEAILITWTKRFKASGVEGADVVKLLNKAIKKRGD Sbjct: 143 EKRKIKDKKLPVGFTFSFPCQQSKIDEAILITWTKRFKASGVEGADVVKLLNKAIKKRGD 202 Query: 198 YDANIVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYMEELRHIDLVEGDEGRMCIN 257 YDANIVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYMEELRHIDLVEGDEGRMCIN Sbjct: 203 YDANIVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYMEELRHIDLVEGDEGRMCIN 262 Query: 258 TEWGAFGDDGSLEDIRTEFDREIDRGSLNPGKQLFEKMVSGMYLGELVRLILVKMAKEGL 317 TEWGAFGDDGSLEDIRTEFDREIDRGSLNPGKQLFEKMVSGMYLGELVRLILVKMAKEGL Sbjct: 263 TEWGAFGDDGSLEDIRTEFDREIDRGSLNPGKQLFEKMVSGMYLGELVRLILVKMAKEGL 322 Query: 318 LFEGRITPELLTRGKFNTSDVSAIEKNKEGLHNAKEILTRLGVEPSDDDCVSVQHVCTIV 377 LFEGRITPELLTRGKFNTSDVSAIEKNKEGLHNAKEILTRLGVEPSDDDCVSVQHVCTIV Sbjct: 323 LFEGRITPELLTRGKFNTSDVSAIEKNKEGLHNAKEILTRLGVEPSDDDCVSVQHVCTIV 382 Query: 378 SFRSANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKTHPQYSRRFHKTLRRLVPDS 437 SFRSANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKTHPQYSRRFHKTLRRLVPDS Sbjct: 383 SFRSANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKTHPQYSRRFHKTLRRLVPDS 442 Query: 438 DVRFLLSESGSGKGAAMVTAVAYRLAEQHRQIEETLAHFHLTKDMLLEVKKRMRAEMELG 497 DVRFLLSESGSGKGAAMVTAVAYRLAEQHRQIEETLAHFHLTKDMLLEVKKRMRAEMELG Sbjct: 443 DVRFLLSESGSGKGAAMVTAVAYRLAEQHRQIEETLAHFHLTKDMLLEVKKRMRAEMELG 502 Query: 498 LRKQTHNNAVVKMLPSFVRRTPDGTENGDFLALDLGGTNFRVLLVKIRSGKKRTVEMHNK 557 LRKQTHNNAVVKMLPSFVRRTPDGTENGDFLALDLGGTNFRVLLVKIRSGKKRTVEMHNK Sbjct: 503 LRKQTHNNAVVKMLPSFVRRTPDGTENGDFLALDLGGTNFRVLLVKIRSGKKRTVEMHNK 562 Query: 558 IYAIPIEIMQGTGEELFDHIVSCISDFLDYMGIKGPRMPLGFTFSFPCQQTSLDAGILIT 617 IYAIPIEIMQGTGEELFDHIVSCISDFLDYMGIKGPRMPLGFTFSFPCQQTSLDAGILIT Sbjct: 563 IYAIPIEIMQGTGEELFDHIVSCISDFLDYMGIKGPRMPLGFTFSFPCQQTSLDAGILIT 622 Query: 618 WTKGFKATDCVGHDVVTLLRDAIKRREEFDLDVVAVVNDTVGTMMTCAYEEPTCEVGLIV 677 WTKGFKATDCVGHDVVTLLRDAIKRREEFDLDVVAVVNDTVGTMMTCAYEEPTCEVGLIV Sbjct: 623 WTKGFKATDCVGHDVVTLLRDAIKRREEFDLDVVAVVNDTVGTMMTCAYEEPTCEVGLIV 682 Query: 678 GTGSNACYMEEMKNVEMVEGDQGQMCINMEWGAFGDNGCLDDIRTHYDRLVDEYSLNAGK 737 GTGSNACYMEEMKNVEMVEGDQGQMCINMEWGAFGDNGCLDDIRTHYDRLVDEYSLNAGK Sbjct: 683 GTGSNACYMEEMKNVEMVEGDQGQMCINMEWGAFGDNGCLDDIRTHYDRLVDEYSLNAGK 742 Query: 738 QRYEKMISGMYLGEIVRNILIDFTKKGFLFRGQISETLKTRGIFETKFLSQIESDRLALL 797 QRYEKMISGMYLGEIVRNILIDFTKKGFLFRGQISETLKTRGIFETKFLSQIESDRLALL Sbjct: 743 QRYEKMISGMYLGEIVRNILIDFTKKGFLFRGQISETLKTRGIFETKFLSQIESDRLALL 802 Query: 798 QVRAILQQLGLNSTCDDSILVKTVCGVVSRRAAQLCGAGMAAVVDKIRENRGLDRLNVTV 857 QVRAILQQLGLNSTCDDSILVKTVCGVVSRRAAQLCGAGMAAVVDKIRENRGLDRLNVTV Sbjct: 803 QVRAILQQLGLNSTCDDSILVKTVCGVVSRRAAQLCGAGMAAVVDKIRENRGLDRLNVTV 862 Query: 858 GVDGTLYKLHPHFSRIMHQTVKELSPKCNVSFLLSEDGSGKGAALITAVGVRLRTEASS 916 GVDGTLYKLHPHFSRIMHQTVKELSPKCNVSFLLSEDGSGKGAALITAVGVRLRTEASS Sbjct: 863 GVDGTLYKLHPHFSRIMHQTVKELSPKCNVSFLLSEDGSGKGAALITAVGVRLRTEASS 921 >gi|188497750 hexokinase 1 isoform HKI-td [Homo sapiens] Length = 905 Score = 1788 bits (4631), Expect = 0.0 Identities = 896/896 (100%), Positives = 896/896 (100%) Query: 21 IDKYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEKGDFI 80 IDKYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEKGDFI Sbjct: 10 IDKYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEKGDFI 69 Query: 81 ALDLGGSSFRILRVQVNHEKNQNVHMESEVYDTPENIVHGSGSQLFDHVAECLGDFMEKR 140 ALDLGGSSFRILRVQVNHEKNQNVHMESEVYDTPENIVHGSGSQLFDHVAECLGDFMEKR Sbjct: 70 ALDLGGSSFRILRVQVNHEKNQNVHMESEVYDTPENIVHGSGSQLFDHVAECLGDFMEKR 129 Query: 141 KIKDKKLPVGFTFSFPCQQSKIDEAILITWTKRFKASGVEGADVVKLLNKAIKKRGDYDA 200 KIKDKKLPVGFTFSFPCQQSKIDEAILITWTKRFKASGVEGADVVKLLNKAIKKRGDYDA Sbjct: 130 KIKDKKLPVGFTFSFPCQQSKIDEAILITWTKRFKASGVEGADVVKLLNKAIKKRGDYDA 189 Query: 201 NIVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYMEELRHIDLVEGDEGRMCINTEW 260 NIVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYMEELRHIDLVEGDEGRMCINTEW Sbjct: 190 NIVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYMEELRHIDLVEGDEGRMCINTEW 249 Query: 261 GAFGDDGSLEDIRTEFDREIDRGSLNPGKQLFEKMVSGMYLGELVRLILVKMAKEGLLFE 320 GAFGDDGSLEDIRTEFDREIDRGSLNPGKQLFEKMVSGMYLGELVRLILVKMAKEGLLFE Sbjct: 250 GAFGDDGSLEDIRTEFDREIDRGSLNPGKQLFEKMVSGMYLGELVRLILVKMAKEGLLFE 309 Query: 321 GRITPELLTRGKFNTSDVSAIEKNKEGLHNAKEILTRLGVEPSDDDCVSVQHVCTIVSFR 380 GRITPELLTRGKFNTSDVSAIEKNKEGLHNAKEILTRLGVEPSDDDCVSVQHVCTIVSFR Sbjct: 310 GRITPELLTRGKFNTSDVSAIEKNKEGLHNAKEILTRLGVEPSDDDCVSVQHVCTIVSFR 369 Query: 381 SANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKTHPQYSRRFHKTLRRLVPDSDVR 440 SANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKTHPQYSRRFHKTLRRLVPDSDVR Sbjct: 370 SANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKTHPQYSRRFHKTLRRLVPDSDVR 429 Query: 441 FLLSESGSGKGAAMVTAVAYRLAEQHRQIEETLAHFHLTKDMLLEVKKRMRAEMELGLRK 500 FLLSESGSGKGAAMVTAVAYRLAEQHRQIEETLAHFHLTKDMLLEVKKRMRAEMELGLRK Sbjct: 430 FLLSESGSGKGAAMVTAVAYRLAEQHRQIEETLAHFHLTKDMLLEVKKRMRAEMELGLRK 489 Query: 501 QTHNNAVVKMLPSFVRRTPDGTENGDFLALDLGGTNFRVLLVKIRSGKKRTVEMHNKIYA 560 QTHNNAVVKMLPSFVRRTPDGTENGDFLALDLGGTNFRVLLVKIRSGKKRTVEMHNKIYA Sbjct: 490 QTHNNAVVKMLPSFVRRTPDGTENGDFLALDLGGTNFRVLLVKIRSGKKRTVEMHNKIYA 549 Query: 561 IPIEIMQGTGEELFDHIVSCISDFLDYMGIKGPRMPLGFTFSFPCQQTSLDAGILITWTK 620 IPIEIMQGTGEELFDHIVSCISDFLDYMGIKGPRMPLGFTFSFPCQQTSLDAGILITWTK Sbjct: 550 IPIEIMQGTGEELFDHIVSCISDFLDYMGIKGPRMPLGFTFSFPCQQTSLDAGILITWTK 609 Query: 621 GFKATDCVGHDVVTLLRDAIKRREEFDLDVVAVVNDTVGTMMTCAYEEPTCEVGLIVGTG 680 GFKATDCVGHDVVTLLRDAIKRREEFDLDVVAVVNDTVGTMMTCAYEEPTCEVGLIVGTG Sbjct: 610 GFKATDCVGHDVVTLLRDAIKRREEFDLDVVAVVNDTVGTMMTCAYEEPTCEVGLIVGTG 669 Query: 681 SNACYMEEMKNVEMVEGDQGQMCINMEWGAFGDNGCLDDIRTHYDRLVDEYSLNAGKQRY 740 SNACYMEEMKNVEMVEGDQGQMCINMEWGAFGDNGCLDDIRTHYDRLVDEYSLNAGKQRY Sbjct: 670 SNACYMEEMKNVEMVEGDQGQMCINMEWGAFGDNGCLDDIRTHYDRLVDEYSLNAGKQRY 729 Query: 741 EKMISGMYLGEIVRNILIDFTKKGFLFRGQISETLKTRGIFETKFLSQIESDRLALLQVR 800 EKMISGMYLGEIVRNILIDFTKKGFLFRGQISETLKTRGIFETKFLSQIESDRLALLQVR Sbjct: 730 EKMISGMYLGEIVRNILIDFTKKGFLFRGQISETLKTRGIFETKFLSQIESDRLALLQVR 789 Query: 801 AILQQLGLNSTCDDSILVKTVCGVVSRRAAQLCGAGMAAVVDKIRENRGLDRLNVTVGVD 860 AILQQLGLNSTCDDSILVKTVCGVVSRRAAQLCGAGMAAVVDKIRENRGLDRLNVTVGVD Sbjct: 790 AILQQLGLNSTCDDSILVKTVCGVVSRRAAQLCGAGMAAVVDKIRENRGLDRLNVTVGVD 849 Query: 861 GTLYKLHPHFSRIMHQTVKELSPKCNVSFLLSEDGSGKGAALITAVGVRLRTEASS 916 GTLYKLHPHFSRIMHQTVKELSPKCNVSFLLSEDGSGKGAALITAVGVRLRTEASS Sbjct: 850 GTLYKLHPHFSRIMHQTVKELSPKCNVSFLLSEDGSGKGAALITAVGVRLRTEASS 905 Score = 494 bits (1271), Expect = e-139 Identities = 235/445 (52%), Positives = 325/445 (73%) Query: 466 HRQIEETLAHFHLTKDMLLEVKKRMRAEMELGLRKQTHNNAVVKMLPSFVRRTPDGTENG 525 H I++ L L+ + L+++ R R EM+ GL + + A VKMLP+FVR PDG+E G Sbjct: 7 HDFIDKYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEKG 66 Query: 526 DFLALDLGGTNFRVLLVKIRSGKKRTVEMHNKIYAIPIEIMQGTGEELFDHIVSCISDFL 585 DF+ALDLGG++FR+L V++ K + V M +++Y P I+ G+G +LFDH+ C+ DF+ Sbjct: 67 DFIALDLGGSSFRILRVQVNHEKNQNVHMESEVYDTPENIVHGSGSQLFDHVAECLGDFM 126 Query: 586 DYMGIKGPRMPLGFTFSFPCQQTSLDAGILITWTKGFKATDCVGHDVVTLLRDAIKRREE 645 + IK ++P+GFTFSFPCQQ+ +D ILITWTK FKA+ G DVV LL AIK+R + Sbjct: 127 EKRKIKDKKLPVGFTFSFPCQQSKIDEAILITWTKRFKASGVEGADVVKLLNKAIKKRGD 186 Query: 646 FDLDVVAVVNDTVGTMMTCAYEEPTCEVGLIVGTGSNACYMEEMKNVEMVEGDQGQMCIN 705 +D ++VAVVNDTVGTMMTC Y++ CEVGLI+GTG+NACYMEE++++++VEGD+G+MCIN Sbjct: 187 YDANIVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYMEELRHIDLVEGDEGRMCIN 246 Query: 706 MEWGAFGDNGCLDDIRTHYDRLVDEYSLNAGKQRYEKMISGMYLGEIVRNILIDFTKKGF 765 EWGAFGD+G L+DIRT +DR +D SLN GKQ +EKM+SGMYLGE+VR IL+ K+G Sbjct: 247 TEWGAFGDDGSLEDIRTEFDREIDRGSLNPGKQLFEKMVSGMYLGELVRLILVKMAKEGL 306 Query: 766 LFRGQISETLKTRGIFETKFLSQIESDRLALLQVRAILQQLGLNSTCDDSILVKTVCGVV 825 LF G+I+ L TRG F T +S IE ++ L + IL +LG+ + DD + V+ VC +V Sbjct: 307 LFEGRITPELLTRGKFNTSDVSAIEKNKEGLHNAKEILTRLGVEPSDDDCVSVQHVCTIV 366 Query: 826 SRRAAQLCGAGMAAVVDKIRENRGLDRLNVTVGVDGTLYKLHPHFSRIMHQTVKELSPKC 885 S R+A L A + A+++++R+N+G RL TVGVDG+LYK HP +SR H+T++ L P Sbjct: 367 SFRSANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKTHPQYSRRFHKTLRRLVPDS 426 Query: 886 NVSFLLSEDGSGKGAALITAVGVRL 910 +V FLLSE GSGKGAA++TAV RL Sbjct: 427 DVRFLLSESGSGKGAAMVTAVAYRL 451 >gi|188497754 hexokinase 1 isoform HKI [Homo sapiens] Length = 917 Score = 1788 bits (4631), Expect = 0.0 Identities = 896/896 (100%), Positives = 896/896 (100%) Query: 21 IDKYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEKGDFI 80 IDKYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEKGDFI Sbjct: 22 IDKYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEKGDFI 81 Query: 81 ALDLGGSSFRILRVQVNHEKNQNVHMESEVYDTPENIVHGSGSQLFDHVAECLGDFMEKR 140 ALDLGGSSFRILRVQVNHEKNQNVHMESEVYDTPENIVHGSGSQLFDHVAECLGDFMEKR Sbjct: 82 ALDLGGSSFRILRVQVNHEKNQNVHMESEVYDTPENIVHGSGSQLFDHVAECLGDFMEKR 141 Query: 141 KIKDKKLPVGFTFSFPCQQSKIDEAILITWTKRFKASGVEGADVVKLLNKAIKKRGDYDA 200 KIKDKKLPVGFTFSFPCQQSKIDEAILITWTKRFKASGVEGADVVKLLNKAIKKRGDYDA Sbjct: 142 KIKDKKLPVGFTFSFPCQQSKIDEAILITWTKRFKASGVEGADVVKLLNKAIKKRGDYDA 201 Query: 201 NIVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYMEELRHIDLVEGDEGRMCINTEW 260 NIVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYMEELRHIDLVEGDEGRMCINTEW Sbjct: 202 NIVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYMEELRHIDLVEGDEGRMCINTEW 261 Query: 261 GAFGDDGSLEDIRTEFDREIDRGSLNPGKQLFEKMVSGMYLGELVRLILVKMAKEGLLFE 320 GAFGDDGSLEDIRTEFDREIDRGSLNPGKQLFEKMVSGMYLGELVRLILVKMAKEGLLFE Sbjct: 262 GAFGDDGSLEDIRTEFDREIDRGSLNPGKQLFEKMVSGMYLGELVRLILVKMAKEGLLFE 321 Query: 321 GRITPELLTRGKFNTSDVSAIEKNKEGLHNAKEILTRLGVEPSDDDCVSVQHVCTIVSFR 380 GRITPELLTRGKFNTSDVSAIEKNKEGLHNAKEILTRLGVEPSDDDCVSVQHVCTIVSFR Sbjct: 322 GRITPELLTRGKFNTSDVSAIEKNKEGLHNAKEILTRLGVEPSDDDCVSVQHVCTIVSFR 381 Query: 381 SANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKTHPQYSRRFHKTLRRLVPDSDVR 440 SANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKTHPQYSRRFHKTLRRLVPDSDVR Sbjct: 382 SANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKTHPQYSRRFHKTLRRLVPDSDVR 441 Query: 441 FLLSESGSGKGAAMVTAVAYRLAEQHRQIEETLAHFHLTKDMLLEVKKRMRAEMELGLRK 500 FLLSESGSGKGAAMVTAVAYRLAEQHRQIEETLAHFHLTKDMLLEVKKRMRAEMELGLRK Sbjct: 442 FLLSESGSGKGAAMVTAVAYRLAEQHRQIEETLAHFHLTKDMLLEVKKRMRAEMELGLRK 501 Query: 501 QTHNNAVVKMLPSFVRRTPDGTENGDFLALDLGGTNFRVLLVKIRSGKKRTVEMHNKIYA 560 QTHNNAVVKMLPSFVRRTPDGTENGDFLALDLGGTNFRVLLVKIRSGKKRTVEMHNKIYA Sbjct: 502 QTHNNAVVKMLPSFVRRTPDGTENGDFLALDLGGTNFRVLLVKIRSGKKRTVEMHNKIYA 561 Query: 561 IPIEIMQGTGEELFDHIVSCISDFLDYMGIKGPRMPLGFTFSFPCQQTSLDAGILITWTK 620 IPIEIMQGTGEELFDHIVSCISDFLDYMGIKGPRMPLGFTFSFPCQQTSLDAGILITWTK Sbjct: 562 IPIEIMQGTGEELFDHIVSCISDFLDYMGIKGPRMPLGFTFSFPCQQTSLDAGILITWTK 621 Query: 621 GFKATDCVGHDVVTLLRDAIKRREEFDLDVVAVVNDTVGTMMTCAYEEPTCEVGLIVGTG 680 GFKATDCVGHDVVTLLRDAIKRREEFDLDVVAVVNDTVGTMMTCAYEEPTCEVGLIVGTG Sbjct: 622 GFKATDCVGHDVVTLLRDAIKRREEFDLDVVAVVNDTVGTMMTCAYEEPTCEVGLIVGTG 681 Query: 681 SNACYMEEMKNVEMVEGDQGQMCINMEWGAFGDNGCLDDIRTHYDRLVDEYSLNAGKQRY 740 SNACYMEEMKNVEMVEGDQGQMCINMEWGAFGDNGCLDDIRTHYDRLVDEYSLNAGKQRY Sbjct: 682 SNACYMEEMKNVEMVEGDQGQMCINMEWGAFGDNGCLDDIRTHYDRLVDEYSLNAGKQRY 741 Query: 741 EKMISGMYLGEIVRNILIDFTKKGFLFRGQISETLKTRGIFETKFLSQIESDRLALLQVR 800 EKMISGMYLGEIVRNILIDFTKKGFLFRGQISETLKTRGIFETKFLSQIESDRLALLQVR Sbjct: 742 EKMISGMYLGEIVRNILIDFTKKGFLFRGQISETLKTRGIFETKFLSQIESDRLALLQVR 801 Query: 801 AILQQLGLNSTCDDSILVKTVCGVVSRRAAQLCGAGMAAVVDKIRENRGLDRLNVTVGVD 860 AILQQLGLNSTCDDSILVKTVCGVVSRRAAQLCGAGMAAVVDKIRENRGLDRLNVTVGVD Sbjct: 802 AILQQLGLNSTCDDSILVKTVCGVVSRRAAQLCGAGMAAVVDKIRENRGLDRLNVTVGVD 861 Query: 861 GTLYKLHPHFSRIMHQTVKELSPKCNVSFLLSEDGSGKGAALITAVGVRLRTEASS 916 GTLYKLHPHFSRIMHQTVKELSPKCNVSFLLSEDGSGKGAALITAVGVRLRTEASS Sbjct: 862 GTLYKLHPHFSRIMHQTVKELSPKCNVSFLLSEDGSGKGAALITAVGVRLRTEASS 917 Score = 495 bits (1275), Expect = e-140 Identities = 235/447 (52%), Positives = 328/447 (73%) Query: 464 EQHRQIEETLAHFHLTKDMLLEVKKRMRAEMELGLRKQTHNNAVVKMLPSFVRRTPDGTE 523 +Q ++I++ L L+ + L+++ R R EM+ GL + + A VKMLP+FVR PDG+E Sbjct: 17 DQVKKIDKYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSE 76 Query: 524 NGDFLALDLGGTNFRVLLVKIRSGKKRTVEMHNKIYAIPIEIMQGTGEELFDHIVSCISD 583 GDF+ALDLGG++FR+L V++ K + V M +++Y P I+ G+G +LFDH+ C+ D Sbjct: 77 KGDFIALDLGGSSFRILRVQVNHEKNQNVHMESEVYDTPENIVHGSGSQLFDHVAECLGD 136 Query: 584 FLDYMGIKGPRMPLGFTFSFPCQQTSLDAGILITWTKGFKATDCVGHDVVTLLRDAIKRR 643 F++ IK ++P+GFTFSFPCQQ+ +D ILITWTK FKA+ G DVV LL AIK+R Sbjct: 137 FMEKRKIKDKKLPVGFTFSFPCQQSKIDEAILITWTKRFKASGVEGADVVKLLNKAIKKR 196 Query: 644 EEFDLDVVAVVNDTVGTMMTCAYEEPTCEVGLIVGTGSNACYMEEMKNVEMVEGDQGQMC 703 ++D ++VAVVNDTVGTMMTC Y++ CEVGLI+GTG+NACYMEE++++++VEGD+G+MC Sbjct: 197 GDYDANIVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYMEELRHIDLVEGDEGRMC 256 Query: 704 INMEWGAFGDNGCLDDIRTHYDRLVDEYSLNAGKQRYEKMISGMYLGEIVRNILIDFTKK 763 IN EWGAFGD+G L+DIRT +DR +D SLN GKQ +EKM+SGMYLGE+VR IL+ K+ Sbjct: 257 INTEWGAFGDDGSLEDIRTEFDREIDRGSLNPGKQLFEKMVSGMYLGELVRLILVKMAKE 316 Query: 764 GFLFRGQISETLKTRGIFETKFLSQIESDRLALLQVRAILQQLGLNSTCDDSILVKTVCG 823 G LF G+I+ L TRG F T +S IE ++ L + IL +LG+ + DD + V+ VC Sbjct: 317 GLLFEGRITPELLTRGKFNTSDVSAIEKNKEGLHNAKEILTRLGVEPSDDDCVSVQHVCT 376 Query: 824 VVSRRAAQLCGAGMAAVVDKIRENRGLDRLNVTVGVDGTLYKLHPHFSRIMHQTVKELSP 883 +VS R+A L A + A+++++R+N+G RL TVGVDG+LYK HP +SR H+T++ L P Sbjct: 377 IVSFRSANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKTHPQYSRRFHKTLRRLVP 436 Query: 884 KCNVSFLLSEDGSGKGAALITAVGVRL 910 +V FLLSE GSGKGAA++TAV RL Sbjct: 437 DSDVRFLLSESGSGKGAAMVTAVAYRL 463 >gi|15553127 hexokinase 2 [Homo sapiens] Length = 917 Score = 1368 bits (3542), Expect = 0.0 Identities = 658/891 (73%), Positives = 775/891 (86%) Query: 21 IDKYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEKGDFI 80 +D+YLY MRLSDETL++I RFRKEM+ GL +PTA VKMLPTFVRS PDG+E G+F+ Sbjct: 22 VDQYLYHMRLSDETLLEISKRFRKEMEKGLGATTHPTAAVKMLPTFVRSTPDGTEHGEFL 81 Query: 81 ALDLGGSSFRILRVQVNHEKNQNVHMESEVYDTPENIVHGSGSQLFDHVAECLGDFMEKR 140 ALDLGG++FR+L V+V Q V ME+++Y PE+I+ GSG+QLFDH+AECL +FM+K Sbjct: 82 ALDLGGTNFRVLWVKVTDNGLQKVEMENQIYAIPEDIMRGSGTQLFDHIAECLANFMDKL 141 Query: 141 KIKDKKLPVGFTFSFPCQQSKIDEAILITWTKRFKASGVEGADVVKLLNKAIKKRGDYDA 200 +IKDKKLP+GFTFSFPC Q+K+DE+ L++WTK FK+SGVEG DVV L+ KAI++RGD+D Sbjct: 142 QIKDKKLPLGFTFSFPCHQTKLDESFLVSWTKGFKSSGVEGRDVVALIRKAIQRRGDFDI 201 Query: 201 NIVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYMEELRHIDLVEGDEGRMCINTEW 260 +IVAVVNDTVGTMMTCGYDD +CE+GLI+GTG+NACYMEE+RHID+VEGDEGRMCIN EW Sbjct: 202 DIVAVVNDTVGTMMTCGYDDHNCEIGLIVGTGSNACYMEEMRHIDMVEGDEGRMCINMEW 261 Query: 261 GAFGDDGSLEDIRTEFDREIDRGSLNPGKQLFEKMVSGMYLGELVRLILVKMAKEGLLFE 320 GAFGDDGSL DIRTEFD+EID GSLNPGKQLFEKM+SGMY+GELVRLILVKMAKE LLF Sbjct: 262 GAFGDDGSLNDIRTEFDQEIDMGSLNPGKQLFEKMISGMYMGELVRLILVKMAKEELLFG 321 Query: 321 GRITPELLTRGKFNTSDVSAIEKNKEGLHNAKEILTRLGVEPSDDDCVSVQHVCTIVSFR 380 G+++PELL G+F T D+S IE K+G+ A+E+L RLG++P+ +DCV+ +C IVS R Sbjct: 322 GKLSPELLNTGRFETKDISDIEGEKDGIRKAREVLMRLGLDPTQEDCVATHRICQIVSTR 381 Query: 381 SANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKTHPQYSRRFHKTLRRLVPDSDVR 440 SA+L AATL A+L R+++NKG RLR+T+GVDGS+YK HP +++R HKT+RRLVP DVR Sbjct: 382 SASLCAATLAAVLQRIKENKGEERLRSTIGVDGSVYKKHPHFAKRLHKTVRRLVPGCDVR 441 Query: 441 FLLSESGSGKGAAMVTAVAYRLAEQHRQIEETLAHFHLTKDMLLEVKKRMRAEMELGLRK 500 FL SE GSGKGAAMVTAVAYRLA+QHR ++TL H L+ D LLEVK+RM+ EME GL K Sbjct: 442 FLRSEDGSGKGAAMVTAVAYRLADQHRARQKTLEHLQLSHDQLLEVKRRMKVEMERGLSK 501 Query: 501 QTHNNAVVKMLPSFVRRTPDGTENGDFLALDLGGTNFRVLLVKIRSGKKRTVEMHNKIYA 560 +TH +A VKMLP++V TPDGTE GDFLALDLGGTNFRVLLV++R+GK VEMHNKIYA Sbjct: 502 ETHASAPVKMLPTYVCATPDGTEKGDFLALDLGGTNFRVLLVRVRNGKWGGVEMHNKIYA 561 Query: 561 IPIEIMQGTGEELFDHIVSCISDFLDYMGIKGPRMPLGFTFSFPCQQTSLDAGILITWTK 620 IP E+M GTG+ELFDHIV CI+DFL+YMG+KG +PLGFTFSFPCQQ SLD IL+ WTK Sbjct: 562 IPQEVMHGTGDELFDHIVQCIADFLEYMGMKGVSLPLGFTFSFPCQQNSLDESILLKWTK 621 Query: 621 GFKATDCVGHDVVTLLRDAIKRREEFDLDVVAVVNDTVGTMMTCAYEEPTCEVGLIVGTG 680 GFKA+ C G DVVTLL++AI RREEFDLDVVAVVNDTVGTMMTC +E+P CEVGLIVGTG Sbjct: 622 GFKASGCEGEDVVTLLKEAIHRREEFDLDVVAVVNDTVGTMMTCGFEDPHCEVGLIVGTG 681 Query: 681 SNACYMEEMKNVEMVEGDQGQMCINMEWGAFGDNGCLDDIRTHYDRLVDEYSLNAGKQRY 740 SNACYMEEM+NVE+VEG++G+MC+NMEWGAFGDNGCLDD RT +D VDE SLN GKQR+ Sbjct: 682 SNACYMEEMRNVELVEGEEGRMCVNMEWGAFGDNGCLDDFRTEFDVAVDELSLNPGKQRF 741 Query: 741 EKMISGMYLGEIVRNILIDFTKKGFLFRGQISETLKTRGIFETKFLSQIESDRLALLQVR 800 EKMISGMYLGEIVRNILIDFTK+G LFRG+ISE LKTRGIFETKFLSQIESD LALLQVR Sbjct: 742 EKMISGMYLGEIVRNILIDFTKRGLLFRGRISERLKTRGIFETKFLSQIESDCLALLQVR 801 Query: 801 AILQQLGLNSTCDDSILVKTVCGVVSRRAAQLCGAGMAAVVDKIRENRGLDRLNVTVGVD 860 AILQ LGL STCDDSI+VK VC VV+RRAAQLCGAGMAAVVD+IRENRGLD L VTVGVD Sbjct: 802 AILQHLGLESTCDDSIIVKEVCTVVARRAAQLCGAGMAAVVDRIRENRGLDALKVTVGVD 861 Query: 861 GTLYKLHPHFSRIMHQTVKELSPKCNVSFLLSEDGSGKGAALITAVGVRLR 911 GTLYKLHPHF+++MH+TVK+L+PKC+VSFL SEDGSGKGAALITAV R+R Sbjct: 862 GTLYKLHPHFAKVMHETVKDLAPKCDVSFLQSEDGSGKGAALITAVACRIR 912 Score = 546 bits (1406), Expect = e-155 Identities = 258/447 (57%), Positives = 344/447 (76%) Query: 464 EQHRQIEETLAHFHLTKDMLLEVKKRMRAEMELGLRKQTHNNAVVKMLPSFVRRTPDGTE 523 +Q +++++ L H L+ + LLE+ KR R EME GL TH A VKMLP+FVR TPDGTE Sbjct: 17 DQVQKVDQYLYHMRLSDETLLEISKRFRKEMEKGLGATTHPTAAVKMLPTFVRSTPDGTE 76 Query: 524 NGDFLALDLGGTNFRVLLVKIRSGKKRTVEMHNKIYAIPIEIMQGTGEELFDHIVSCISD 583 +G+FLALDLGGTNFRVL VK+ + VEM N+IYAIP +IM+G+G +LFDHI C+++ Sbjct: 77 HGEFLALDLGGTNFRVLWVKVTDNGLQKVEMENQIYAIPEDIMRGSGTQLFDHIAECLAN 136 Query: 584 FLDYMGIKGPRMPLGFTFSFPCQQTSLDAGILITWTKGFKATDCVGHDVVTLLRDAIKRR 643 F+D + IK ++PLGFTFSFPC QT LD L++WTKGFK++ G DVV L+R AI+RR Sbjct: 137 FMDKLQIKDKKLPLGFTFSFPCHQTKLDESFLVSWTKGFKSSGVEGRDVVALIRKAIQRR 196 Query: 644 EEFDLDVVAVVNDTVGTMMTCAYEEPTCEVGLIVGTGSNACYMEEMKNVEMVEGDQGQMC 703 +FD+D+VAVVNDTVGTMMTC Y++ CE+GLIVGTGSNACYMEEM++++MVEGD+G+MC Sbjct: 197 GDFDIDIVAVVNDTVGTMMTCGYDDHNCEIGLIVGTGSNACYMEEMRHIDMVEGDEGRMC 256 Query: 704 INMEWGAFGDNGCLDDIRTHYDRLVDEYSLNAGKQRYEKMISGMYLGEIVRNILIDFTKK 763 INMEWGAFGD+G L+DIRT +D+ +D SLN GKQ +EKMISGMY+GE+VR IL+ K+ Sbjct: 257 INMEWGAFGDDGSLNDIRTEFDQEIDMGSLNPGKQLFEKMISGMYMGELVRLILVKMAKE 316 Query: 764 GFLFRGQISETLKTRGIFETKFLSQIESDRLALLQVRAILQQLGLNSTCDDSILVKTVCG 823 LF G++S L G FETK +S IE ++ + + R +L +LGL+ T +D + +C Sbjct: 317 ELLFGGKLSPELLNTGRFETKDISDIEGEKDGIRKAREVLMRLGLDPTQEDCVATHRICQ 376 Query: 824 VVSRRAAQLCGAGMAAVVDKIRENRGLDRLNVTVGVDGTLYKLHPHFSRIMHQTVKELSP 883 +VS R+A LC A +AAV+ +I+EN+G +RL T+GVDG++YK HPHF++ +H+TV+ L P Sbjct: 377 IVSTRSASLCAATLAAVLQRIKENKGEERLRSTIGVDGSVYKKHPHFAKRLHKTVRRLVP 436 Query: 884 KCNVSFLLSEDGSGKGAALITAVGVRL 910 C+V FL SEDGSGKGAA++TAV RL Sbjct: 437 GCDVRFLRSEDGSGKGAAMVTAVAYRL 463 Score = 521 bits (1342), Expect = e-147 Identities = 246/442 (55%), Positives = 336/442 (76%) Query: 23 KYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEKGDFIAL 82 K L ++LS + L+++ R + EM+ GLS++ + +A VKMLPT+V + PDG+EKGDF+AL Sbjct: 472 KTLEHLQLSHDQLLEVKRRMKVEMERGLSKETHASAPVKMLPTYVCATPDGTEKGDFLAL 531 Query: 83 DLGGSSFRILRVQVNHEKNQNVHMESEVYDTPENIVHGSGSQLFDHVAECLGDFMEKRKI 142 DLGG++FR+L V+V + K V M +++Y P+ ++HG+G +LFDH+ +C+ DF+E + Sbjct: 532 DLGGTNFRVLLVRVRNGKWGGVEMHNKIYAIPQEVMHGTGDELFDHIVQCIADFLEYMGM 591 Query: 143 KDKKLPVGFTFSFPCQQSKIDEAILITWTKRFKASGVEGADVVKLLNKAIKKRGDYDANI 202 K LP+GFTFSFPCQQ+ +DE+IL+ WTK FKASG EG DVV LL +AI +R ++D ++ Sbjct: 592 KGVSLPLGFTFSFPCQQNSLDESILLKWTKGFKASGCEGEDVVTLLKEAIHRREEFDLDV 651 Query: 203 VAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYMEELRHIDLVEGDEGRMCINTEWGA 262 VAVVNDTVGTMMTCG++D HCEVGLI+GTG+NACYMEE+R+++LVEG+EGRMC+N EWGA Sbjct: 652 VAVVNDTVGTMMTCGFEDPHCEVGLIVGTGSNACYMEEMRNVELVEGEEGRMCVNMEWGA 711 Query: 263 FGDDGSLEDIRTEFDREIDRGSLNPGKQLFEKMVSGMYLGELVRLILVKMAKEGLLFEGR 322 FGD+G L+D RTEFD +D SLNPGKQ FEKM+SGMYLGE+VR IL+ K GLLF GR Sbjct: 712 FGDNGCLDDFRTEFDVAVDELSLNPGKQRFEKMISGMYLGEIVRNILIDFTKRGLLFRGR 771 Query: 323 ITPELLTRGKFNTSDVSAIEKNKEGLHNAKEILTRLGVEPSDDDCVSVQHVCTIVSFRSA 382 I+ L TRG F T +S IE + L + IL LG+E + DD + V+ VCT+V+ R+A Sbjct: 772 ISERLKTRGIFETKFLSQIESDCLALLQVRAILQHLGLESTCDDSIIVKEVCTVVARRAA 831 Query: 383 NLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKTHPQYSRRFHKTLRRLVPDSDVRFL 442 L A + A+++R+R+N+G L+ TVGVDG+LYK HP +++ H+T++ L P DV FL Sbjct: 832 QLCGAGMAAVVDRIRENRGLDALKVTVGVDGTLYKLHPHFAKVMHETVKDLAPKCDVSFL 891 Query: 443 LSESGSGKGAAMVTAVAYRLAE 464 SE GSGKGAA++TAVA R+ E Sbjct: 892 QSEDGSGKGAALITAVACRIRE 913 >gi|156151420 hexokinase domain containing 1 [Homo sapiens] Length = 917 Score = 1323 bits (3424), Expect = 0.0 Identities = 639/891 (71%), Positives = 764/891 (85%), Gaps = 1/891 (0%) Query: 21 IDKYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEKGDFI 80 +D++LY MRLSD+TL+DIM RFR EM+ GL++D NPTA VKMLPTFVR+IPDGSE G+F+ Sbjct: 22 VDRFLYHMRLSDDTLLDIMRRFRAEMEKGLAKDTNPTAAVKMLPTFVRAIPDGSENGEFL 81 Query: 81 ALDLGGSSFRILRVQVNHEKNQNVHMESEVYDTPENIVHGSGSQLFDHVAECLGDFMEKR 140 +LDLGGS FR+L+VQV E ++V MES+ Y TP I+ G+G++LF++VA+CL DFM+ + Sbjct: 82 SLDLGGSKFRVLKVQVAEEGKRHVQMESQFYPTPNEIIRGNGTELFEYVADCLADFMKTK 141 Query: 141 KIKDKKLPVGFTFSFPCQQSKIDEAILITWTKRFKASGVEGADVVKLLNKAIKKRGDYDA 200 +K KKLP+G TFSFPC+Q+K++E +L++WTK+FKA GV+ DVV L KA+++ D D Sbjct: 142 DLKHKKLPLGLTFSFPCRQTKLEEGVLLSWTKKFKARGVQDTDVVSRLTKAMRRHKDMDV 201 Query: 201 NIVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYMEELRHIDLVEGDEGRMCINTEW 260 +I+A+VNDTVGTMMTC YDD +CEVG+IIGTGTNACYME++ +IDLVEGDEGRMCINTEW Sbjct: 202 DILALVNDTVGTMMTCAYDDPYCEVGVIIGTGTNACYMEDMSNIDLVEGDEGRMCINTEW 261 Query: 261 GAFGDDGSLEDIRTEFDREIDRGSLNPGKQLFEKMVSGMYLGELVRLILVKMAKEGLLFE 320 GAFGDDG+LEDIRTEFDRE+D GSLNPGKQLFEKM+SG+YLGELVRLIL+KMAK GLLF Sbjct: 262 GAFGDDGALEDIRTEFDRELDLGSLNPGKQLFEKMISGLYLGELVRLILLKMAKAGLLFG 321 Query: 321 GRITPELLTRGKFNTSDVSAIEKNKEGLHNAKEILTRLGVEPSDDDCVSVQHVCTIVSFR 380 G + L T+GK T V+A+EK KEGL N +EIL LG+EPS+ DC++VQHVCTIVSFR Sbjct: 322 GEKSSALHTKGKIETRHVAAMEKYKEGLANTREILVDLGLEPSEADCIAVQHVCTIVSFR 381 Query: 381 SANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKTHPQYSRRFHKTLRRLVPDSDVR 440 SANL AA L AIL RLR+NK RLRTTVG+DG+LYK HPQY +R HK +R+LVP DVR Sbjct: 382 SANLCAAALAAILTRLRENKKVERLRTTVGMDGTLYKIHPQYPKRLHKVVRKLVPSCDVR 441 Query: 441 FLLSESGSGKGAAMVTAVAYRLAEQHRQIEETLAHFHLTKDMLLEVKKRMRAEMELGLRK 500 FLLSESGS KGAAMVTAVA R+ Q +QI+ LA F LT++ L++V+ +MRAE+E GL+K Sbjct: 442 FLLSESGSTKGAAMVTAVASRVQAQRKQIDRVLALFQLTREQLVDVQAKMRAELEYGLKK 501 Query: 501 QTHNNAVVKMLPSFVRRTPDGTENGDFLALDLGGTNFRVLLVKIRSGKKRTVEMHNKIYA 560 ++H A V+MLP++V PDGTE G FLALDLGGTNFRVLLVKIRSG +R+V M+NKI+A Sbjct: 502 KSHGLATVRMLPTYVCGLPDGTEKGKFLALDLGGTNFRVLLVKIRSG-RRSVRMYNKIFA 560 Query: 561 IPIEIMQGTGEELFDHIVSCISDFLDYMGIKGPRMPLGFTFSFPCQQTSLDAGILITWTK 620 IP+EIMQGTGEELFDHIV CI+DFLDYMG+KG +PLGFTFSFPC+Q S+D G LI WTK Sbjct: 561 IPLEIMQGTGEELFDHIVQCIADFLDYMGLKGASLPLGFTFSFPCRQMSIDKGTLIGWTK 620 Query: 621 GFKATDCVGHDVVTLLRDAIKRREEFDLDVVAVVNDTVGTMMTCAYEEPTCEVGLIVGTG 680 GFKATDC G DVV +LR+AIKRR EFDLD+VAVVNDTVGTMMTC YE+P CE+GLI GTG Sbjct: 621 GFKATDCEGEDVVDMLREAIKRRNEFDLDIVAVVNDTVGTMMTCGYEDPNCEIGLIAGTG 680 Query: 681 SNACYMEEMKNVEMVEGDQGQMCINMEWGAFGDNGCLDDIRTHYDRLVDEYSLNAGKQRY 740 SN CYME+M+N+EMVEG +G+MCIN EWG FGDNGC+DDIRT YD VDE SLN GKQRY Sbjct: 681 SNMCYMEDMRNIEMVEGGEGKMCINTEWGGFGDNGCIDDIRTRYDTEVDEGSLNPGKQRY 740 Query: 741 EKMISGMYLGEIVRNILIDFTKKGFLFRGQISETLKTRGIFETKFLSQIESDRLALLQVR 800 EKM SGMYLGEIVR ILID TK+G LFRGQISE L+TRGIFETKFLSQIESDRLALLQVR Sbjct: 741 EKMTSGMYLGEIVRQILIDLTKQGLLFRGQISERLRTRGIFETKFLSQIESDRLALLQVR 800 Query: 801 AILQQLGLNSTCDDSILVKTVCGVVSRRAAQLCGAGMAAVVDKIRENRGLDRLNVTVGVD 860 ILQQLGL+STC+DSI+VK VCG VSRRAAQLCGAG+AA+V+K RE++GL+ L +TVGVD Sbjct: 801 RILQQLGLDSTCEDSIVVKEVCGAVSRRAAQLCGAGLAAIVEKRREDQGLEHLRITVGVD 860 Query: 861 GTLYKLHPHFSRIMHQTVKELSPKCNVSFLLSEDGSGKGAALITAVGVRLR 911 GTLYKLHPHFSRI+ +TVKEL+P+C+V+F+LSEDGSGKGAALITAV RL+ Sbjct: 861 GTLYKLHPHFSRILQETVKELAPRCDVTFMLSEDGSGKGAALITAVAKRLQ 911 Score = 498 bits (1282), Expect = e-140 Identities = 235/450 (52%), Positives = 332/450 (73%) Query: 464 EQHRQIEETLAHFHLTKDMLLEVKKRMRAEMELGLRKQTHNNAVVKMLPSFVRRTPDGTE 523 +Q ++++ L H L+ D LL++ +R RAEME GL K T+ A VKMLP+FVR PDG+E Sbjct: 17 DQIKKVDRFLYHMRLSDDTLLDIMRRFRAEMEKGLAKDTNPTAAVKMLPTFVRAIPDGSE 76 Query: 524 NGDFLALDLGGTNFRVLLVKIRSGKKRTVEMHNKIYAIPIEIMQGTGEELFDHIVSCISD 583 NG+FL+LDLGG+ FRVL V++ KR V+M ++ Y P EI++G G ELF+++ C++D Sbjct: 77 NGEFLSLDLGGSKFRVLKVQVAEEGKRHVQMESQFYPTPNEIIRGNGTELFEYVADCLAD 136 Query: 584 FLDYMGIKGPRMPLGFTFSFPCQQTSLDAGILITWTKGFKATDCVGHDVVTLLRDAIKRR 643 F+ +K ++PLG TFSFPC+QT L+ G+L++WTK FKA DVV+ L A++R Sbjct: 137 FMKTKDLKHKKLPLGLTFSFPCRQTKLEEGVLLSWTKKFKARGVQDTDVVSRLTKAMRRH 196 Query: 644 EEFDLDVVAVVNDTVGTMMTCAYEEPTCEVGLIVGTGSNACYMEEMKNVEMVEGDQGQMC 703 ++ D+D++A+VNDTVGTMMTCAY++P CEVG+I+GTG+NACYME+M N+++VEGD+G+MC Sbjct: 197 KDMDVDILALVNDTVGTMMTCAYDDPYCEVGVIIGTGTNACYMEDMSNIDLVEGDEGRMC 256 Query: 704 INMEWGAFGDNGCLDDIRTHYDRLVDEYSLNAGKQRYEKMISGMYLGEIVRNILIDFTKK 763 IN EWGAFGD+G L+DIRT +DR +D SLN GKQ +EKMISG+YLGE+VR IL+ K Sbjct: 257 INTEWGAFGDDGALEDIRTEFDRELDLGSLNPGKQLFEKMISGLYLGELVRLILLKMAKA 316 Query: 764 GFLFRGQISETLKTRGIFETKFLSQIESDRLALLQVRAILQQLGLNSTCDDSILVKTVCG 823 G LF G+ S L T+G ET+ ++ +E + L R IL LGL + D I V+ VC Sbjct: 317 GLLFGGEKSSALHTKGKIETRHVAAMEKYKEGLANTREILVDLGLEPSEADCIAVQHVCT 376 Query: 824 VVSRRAAQLCGAGMAAVVDKIRENRGLDRLNVTVGVDGTLYKLHPHFSRIMHQTVKELSP 883 +VS R+A LC A +AA++ ++REN+ ++RL TVG+DGTLYK+HP + + +H+ V++L P Sbjct: 377 IVSFRSANLCAAALAAILTRLRENKKVERLRTTVGMDGTLYKIHPQYPKRLHKVVRKLVP 436 Query: 884 KCNVSFLLSEDGSGKGAALITAVGVRLRTE 913 C+V FLLSE GS KGAA++TAV R++ + Sbjct: 437 SCDVRFLLSESGSTKGAAMVTAVASRVQAQ 466 Score = 493 bits (1270), Expect = e-139 Identities = 234/448 (52%), Positives = 330/448 (73%), Gaps = 1/448 (0%) Query: 21 IDKYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEKGDFI 80 ID+ L +L+ E L+D+ + R E++ GL + + ATV+MLPT+V +PDG+EKG F+ Sbjct: 470 IDRVLALFQLTREQLVDVQAKMRAELEYGLKKKSHGLATVRMLPTYVCGLPDGTEKGKFL 529 Query: 81 ALDLGGSSFRILRVQVNHEKNQNVHMESEVYDTPENIVHGSGSQLFDHVAECLGDFMEKR 140 ALDLGG++FR+L V++ + ++V M ++++ P I+ G+G +LFDH+ +C+ DF++ Sbjct: 530 ALDLGGTNFRVLLVKIRSGR-RSVRMYNKIFAIPLEIMQGTGEELFDHIVQCIADFLDYM 588 Query: 141 KIKDKKLPVGFTFSFPCQQSKIDEAILITWTKRFKASGVEGADVVKLLNKAIKKRGDYDA 200 +K LP+GFTFSFPC+Q ID+ LI WTK FKA+ EG DVV +L +AIK+R ++D Sbjct: 589 GLKGASLPLGFTFSFPCRQMSIDKGTLIGWTKGFKATDCEGEDVVDMLREAIKRRNEFDL 648 Query: 201 NIVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYMEELRHIDLVEGDEGRMCINTEW 260 +IVAVVNDTVGTMMTCGY+D +CE+GLI GTG+N CYME++R+I++VEG EG+MCINTEW Sbjct: 649 DIVAVVNDTVGTMMTCGYEDPNCEIGLIAGTGSNMCYMEDMRNIEMVEGGEGKMCINTEW 708 Query: 261 GAFGDDGSLEDIRTEFDREIDRGSLNPGKQLFEKMVSGMYLGELVRLILVKMAKEGLLFE 320 G FGD+G ++DIRT +D E+D GSLNPGKQ +EKM SGMYLGE+VR IL+ + K+GLLF Sbjct: 709 GGFGDNGCIDDIRTRYDTEVDEGSLNPGKQRYEKMTSGMYLGEIVRQILIDLTKQGLLFR 768 Query: 321 GRITPELLTRGKFNTSDVSAIEKNKEGLHNAKEILTRLGVEPSDDDCVSVQHVCTIVSFR 380 G+I+ L TRG F T +S IE ++ L + IL +LG++ + +D + V+ VC VS R Sbjct: 769 GQISERLRTRGIFETKFLSQIESDRLALLQVRRILQQLGLDSTCEDSIVVKEVCGAVSRR 828 Query: 381 SANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKTHPQYSRRFHKTLRRLVPDSDVR 440 +A L A L AI+ + R+++G LR TVGVDG+LYK HP +SR +T++ L P DV Sbjct: 829 AAQLCGAGLAAIVEKRREDQGLEHLRITVGVDGTLYKLHPHFSRILQETVKELAPRCDVT 888 Query: 441 FLLSESGSGKGAAMVTAVAYRLAEQHRQ 468 F+LSE GSGKGAA++TAVA RL + ++ Sbjct: 889 FMLSEDGSGKGAALITAVAKRLQQAQKE 916 >gi|194097330 hexokinase 3 [Homo sapiens] Length = 923 Score = 944 bits (2440), Expect = 0.0 Identities = 478/892 (53%), Positives = 629/892 (70%), Gaps = 9/892 (1%) Query: 21 IDKYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEKGDFI 80 + + L +++ L I M+ L +P V+MLPT+V S P G+E+GDF+ Sbjct: 33 VQECLQQFKVTRAQLQQIQASLLGSMEQALRGQASPAPAVRMLPTYVGSTPHGTEQGDFV 92 Query: 81 ALDLG--GSSFRILRVQVNHEKNQNVHMESEVYDTPENIVHGSGSQLFDHVAECLGDFME 138 L+LG G+S R+L V + + V S+ + P+ ++ G+G QLFD A CL +F++ Sbjct: 93 VLELGATGASLRVLWVTLTGIEGHRVEPRSQEFVIPQEVMLGAGQQLFDFAAHCLSEFLD 152 Query: 139 KRKIKDKKLPVGFTFSFPCQQSKIDEAILITWTKRFKASGVEGADVVKLLNKAIKKRGDY 198 + + + L +GF+FSFPC Q+ +D + LI+WTK F+ SGVEG DVV+LL AI+++G Y Sbjct: 153 AQPVNKQGLQLGFSFSFPCHQTGLDRSTLISWTKGFRCSGVEGQDVVQLLRDAIRRQGAY 212 Query: 199 DANIVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYMEELRHIDLVEGDEGRMCINT 258 + ++VAVVNDTVGTMM C + CEVGL++ TGTNACYMEE RH+ +++ D GR+C++ Sbjct: 213 NIDVVAVVNDTVGTMMGCEPGVRPCEVGLVVDTGTNACYMEEARHVAVLDEDRGRVCVSV 272 Query: 259 EWGAFGDDGSLEDIRTEFDREIDRGSLNPGKQLFEKMVSGMYLGELVRLILVKMAKEGLL 318 EWG+F DDG+L + T FD +D SLNPG Q FEKM+ G+YLGELVRL+L +A+ G+L Sbjct: 273 EWGSFSDDGALGPVLTTFDHTLDHESLNPGAQRFEKMIGGLYLGELVRLVLAHLARCGVL 332 Query: 319 FEGRITPELLTRGKFNTSDVSAIEKNKEGLHNAKEILTRLGVEPSDDDCVSVQHVCTIVS 378 F G +P LL++G V+ +E G IL LG+ P D VQHVC V Sbjct: 333 FGGCTSPALLSQGSILLEHVAEMEDPSTGAARVHAILQDLGLSPGASDVELVQHVCAAVC 392 Query: 379 FRSANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKTHPQYSRRFHKTLRRLVPDSD 438 R+A L AA L A+L+ L+ ++ L+ V G + + HP++ T+ L P+ D Sbjct: 393 TRAAQLCAAALAAVLSCLQHSREQQTLQVAVATGGRVCERHPRFCSVLQGTVMLLAPECD 452 Query: 439 VRFLLSESGSGKGAAMVTAVAYRLAEQHRQIEETLAHFHLTKDMLLEVKKRMRAEMELGL 498 V + S G G+G AMVTAVA RLA R +EETLA F L D L V+ +MR M GL Sbjct: 453 VSLIPSVDGGGRGVAMVTAVAARLAAHRRLLEETLAPFRLNHDQLAAVQAQMRKAMAKGL 512 Query: 499 RKQTHNNAVVKMLPSFVRRTPDGTENGDFLALDLGGTNFRVLLVKIRSGKKRTVEMHNKI 558 R + + ++MLP+FVR TPDG+E GDFLALDLGGTNFRVLLV++ +G V++ ++I Sbjct: 513 RGEASS---LRMLPTFVRATPDGSERGDFLALDLGGTNFRVLLVRVTTG----VQITSEI 565 Query: 559 YAIPIEIMQGTGEELFDHIVSCISDFLDYMGIKGPRMPLGFTFSFPCQQTSLDAGILITW 618 Y+IP + QG+G++LFDHIV CI DF G+ G +PLGFTFSFPC+Q LD GIL+ W Sbjct: 566 YSIPETVAQGSGQQLFDHIVDCIVDFQQKQGLSGQSLPLGFTFSFPCRQLGLDQGILLNW 625 Query: 619 TKGFKATDCVGHDVVTLLRDAIKRREEFDLDVVAVVNDTVGTMMTCAYEEPTCEVGLIVG 678 TKGFKA+DC G DVV+LLR+AI RR+ +L+VVA+VNDTVGTMM+C YE+P CE+GLIVG Sbjct: 626 TKGFKASDCEGQDVVSLLREAITRRQAVELNVVAIVNDTVGTMMSCGYEDPRCEIGLIVG 685 Query: 679 TGSNACYMEEMKNVEMVEGDQGQMCINMEWGAFGDNGCLDDIRTHYDRLVDEYSLNAGKQ 738 TG+NACYMEE++NV V GD G+MCINMEWGAFGD+G L + T +D VD+ S+N GKQ Sbjct: 686 TGTNACYMEELRNVAGVPGDSGRMCINMEWGAFGDDGSLAMLSTRFDASVDQASINPGKQ 745 Query: 739 RYEKMISGMYLGEIVRNILIDFTKKGFLFRGQISETLKTRGIFETKFLSQIESDRLALLQ 798 R+EKMISGMYLGEIVR+IL+ T G LFRGQ + L+TR IF+TKFLS+IESD LAL Q Sbjct: 746 RFEKMISGMYLGEIVRHILLHLTSLGVLFRGQQIQRLQTRDIFKTKFLSEIESDSLALRQ 805 Query: 799 VRAILQQLGLNSTCDDSILVKTVCGVVSRRAAQLCGAGMAAVVDKIRENRGLDRLNVTVG 858 VRAIL+ LGL T DD+++V VC VS+RAAQLCGAG+AAVV+KIRENRGL+ L V+VG Sbjct: 806 VRAILEDLGLPLTSDDALMVLEVCQAVSQRAAQLCGAGVAAVVEKIRENRGLEELAVSVG 865 Query: 859 VDGTLYKLHPHFSRIMHQTVKELSPKCNVSFLLSEDGSGKGAALITAVGVRL 910 VDGTLYKLHP FS ++ TV+EL+P+C V+FL SEDGSGKGAAL+TAV RL Sbjct: 866 VDGTLYKLHPRFSSLVAATVRELAPRCVVTFLQSEDGSGKGAALVTAVACRL 917 Score = 463 bits (1192), Expect = e-130 Identities = 232/447 (51%), Positives = 308/447 (68%), Gaps = 7/447 (1%) Query: 21 IDKYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEKGDFI 80 +++ L RL+ + L + + RK M GL + ++++MLPTFVR+ PDGSE+GDF+ Sbjct: 483 LEETLAPFRLNHDQLAAVQAQMRKAMAKGLRGE---ASSLRMLPTFVRATPDGSERGDFL 539 Query: 81 ALDLGGSSFRILRVQVNHEKNQNVHMESEVYDTPENIVHGSGSQLFDHVAECLGDFMEKR 140 ALDLGG++FR+L V+V V + SE+Y PE + GSG QLFDH+ +C+ DF +K+ Sbjct: 540 ALDLGGTNFRVLLVRVT----TGVQITSEIYSIPETVAQGSGQQLFDHIVDCIVDFQQKQ 595 Query: 141 KIKDKKLPVGFTFSFPCQQSKIDEAILITWTKRFKASGVEGADVVKLLNKAIKKRGDYDA 200 + + LP+GFTFSFPC+Q +D+ IL+ WTK FKAS EG DVV LL +AI +R + Sbjct: 596 GLSGQSLPLGFTFSFPCRQLGLDQGILLNWTKGFKASDCEGQDVVSLLREAITRRQAVEL 655 Query: 201 NIVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYMEELRHIDLVEGDEGRMCINTEW 260 N+VA+VNDTVGTMM+CGY+D CE+GLI+GTGTNACYMEELR++ V GD GRMCIN EW Sbjct: 656 NVVAIVNDTVGTMMSCGYEDPRCEIGLIVGTGTNACYMEELRNVAGVPGDSGRMCINMEW 715 Query: 261 GAFGDDGSLEDIRTEFDREIDRGSLNPGKQLFEKMVSGMYLGELVRLILVKMAKEGLLFE 320 GAFGDDGSL + T FD +D+ S+NPGKQ FEKM+SGMYLGE+VR IL+ + G+LF Sbjct: 716 GAFGDDGSLAMLSTRFDASVDQASINPGKQRFEKMISGMYLGEIVRHILLHLTSLGVLFR 775 Query: 321 GRITPELLTRGKFNTSDVSAIEKNKEGLHNAKEILTRLGVEPSDDDCVSVQHVCTIVSFR 380 G+ L TR F T +S IE + L + IL LG+ + DD + V VC VS R Sbjct: 776 GQQIQRLQTRDIFKTKFLSEIESDSLALRQVRAILEDLGLPLTSDDALMVLEVCQAVSQR 835 Query: 381 SANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKTHPQYSRRFHKTLRRLVPDSDVR 440 +A L A + A++ ++R+N+G L +VGVDG+LYK HP++S T+R L P V Sbjct: 836 AAQLCGAGVAAVVEKIRENRGLEELAVSVGVDGTLYKLHPRFSSLVAATVRELAPRCVVT 895 Query: 441 FLLSESGSGKGAAMVTAVAYRLAEQHR 467 FL SE GSGKGAA+VTAVA RLA+ R Sbjct: 896 FLQSEDGSGKGAALVTAVACRLAQLTR 922 >gi|15967161 glucokinase isoform 3 [Homo sapiens] Length = 464 Score = 506 bits (1304), Expect = e-143 Identities = 245/451 (54%), Positives = 336/451 (74%), Gaps = 2/451 (0%) Query: 461 RLAEQHRQIEETLAHFHLTKDMLLEVKKRMRAEMELGLRKQTHNNAVVKMLPSFVRRTPD 520 +L + + Q+E+ LA F L ++ L +V +RM+ EM+ GLR +TH A VKMLP++VR TP+ Sbjct: 7 QLPQPNSQVEQILAEFQLQEEDLKKVMRRMQKEMDRGLRLETHEEASVKMLPTYVRSTPE 66 Query: 521 GTENGDFLALDLGGTNFRVLLVKIRSGKKR--TVEMHNKIYAIPIEIMQGTGEELFDHIV 578 G+E GDFL+LDLGGTNFRV+LVK+ G++ +V+ +++Y+IP + M GT E LFD+I Sbjct: 67 GSEVGDFLSLDLGGTNFRVMLVKVGEGEEGQWSVKTKHQMYSIPEDAMTGTAEMLFDYIS 126 Query: 579 SCISDFLDYMGIKGPRMPLGFTFSFPCQQTSLDAGILITWTKGFKATDCVGHDVVTLLRD 638 CISDFLD +K ++PLGFTFSFP + +D GIL+ WTKGFKA+ G++VV LLRD Sbjct: 127 ECISDFLDKHQMKHKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGNNVVGLLRD 186 Query: 639 AIKRREEFDLDVVAVVNDTVGTMMTCAYEEPTCEVGLIVGTGSNACYMEEMKNVEMVEGD 698 AIKRR +F++DVVA+VNDTV TM++C YE+ CEVG+IVGTG NACYMEEM+NVE+VEGD Sbjct: 187 AIKRRGDFEMDVVAMVNDTVATMISCYYEDHQCEVGMIVGTGCNACYMEEMQNVELVEGD 246 Query: 699 QGQMCINMEWGAFGDNGCLDDIRTHYDRLVDEYSLNAGKQRYEKMISGMYLGEIVRNILI 758 +G+MC+N EWGAFGD+G LD+ YDRLVDE S N G+Q YEK+I G Y+GE+VR +L+ Sbjct: 247 EGRMCVNTEWGAFGDSGELDEFLLEYDRLVDESSANPGQQLYEKLIGGKYMGELVRLVLL 306 Query: 759 DFTKKGFLFRGQISETLKTRGIFETKFLSQIESDRLALLQVRAILQQLGLNSTCDDSILV 818 + LF G+ SE L+TRG FET+F+SQ+ESD Q+ IL LGL + D +V Sbjct: 307 RLVDENLLFHGEASEQLRTRGAFETRFVSQVESDTGDRKQIYNILSTLGLRPSTTDCDIV 366 Query: 819 KTVCGVVSRRAAQLCGAGMAAVVDKIRENRGLDRLNVTVGVDGTLYKLHPHFSRIMHQTV 878 + C VS RAA +C AG+A V++++RE+R D + +TVGVDG++YKLHP F H +V Sbjct: 367 RRACESVSTRAAHMCSAGLAGVINRMRESRSEDVMRITVGVDGSVYKLHPSFKERFHASV 426 Query: 879 KELSPKCNVSFLLSEDGSGKGAALITAVGVR 909 + L+P C ++F+ SE+GSG+GAAL++AV + Sbjct: 427 RRLTPSCEITFIESEEGSGRGAALVSAVACK 457 Score = 474 bits (1219), Expect = e-133 Identities = 222/445 (49%), Positives = 320/445 (71%), Gaps = 2/445 (0%) Query: 21 IDKYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEKGDFI 80 +++ L +L +E L +M R +KEM GL + + A+VKMLPT+VRS P+GSE GDF+ Sbjct: 15 VEQILAEFQLQEEDLKKVMRRMQKEMDRGLRLETHEEASVKMLPTYVRSTPEGSEVGDFL 74 Query: 81 ALDLGGSSFRILRVQVNH--EKNQNVHMESEVYDTPENIVHGSGSQLFDHVAECLGDFME 138 +LDLGG++FR++ V+V E +V + ++Y PE+ + G+ LFD+++EC+ DF++ Sbjct: 75 SLDLGGTNFRVMLVKVGEGEEGQWSVKTKHQMYSIPEDAMTGTAEMLFDYISECISDFLD 134 Query: 139 KRKIKDKKLPVGFTFSFPCQQSKIDEAILITWTKRFKASGVEGADVVKLLNKAIKKRGDY 198 K ++K KKLP+GFTFSFP + ID+ IL+ WTK FKASG EG +VV LL AIK+RGD+ Sbjct: 135 KHQMKHKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGNNVVGLLRDAIKRRGDF 194 Query: 199 DANIVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYMEELRHIDLVEGDEGRMCINT 258 + ++VA+VNDTV TM++C Y+D CEVG+I+GTG NACYMEE+++++LVEGDEGRMC+NT Sbjct: 195 EMDVVAMVNDTVATMISCYYEDHQCEVGMIVGTGCNACYMEEMQNVELVEGDEGRMCVNT 254 Query: 259 EWGAFGDDGSLEDIRTEFDREIDRGSLNPGKQLFEKMVSGMYLGELVRLILVKMAKEGLL 318 EWGAFGD G L++ E+DR +D S NPG+QL+EK++ G Y+GELVRL+L+++ E LL Sbjct: 255 EWGAFGDSGELDEFLLEYDRLVDESSANPGQQLYEKLIGGKYMGELVRLVLLRLVDENLL 314 Query: 319 FEGRITPELLTRGKFNTSDVSAIEKNKEGLHNAKEILTRLGVEPSDDDCVSVQHVCTIVS 378 F G + +L TRG F T VS +E + IL+ LG+ PS DC V+ C VS Sbjct: 315 FHGEASEQLRTRGAFETRFVSQVESDTGDRKQIYNILSTLGLRPSTTDCDIVRRACESVS 374 Query: 379 FRSANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKTHPQYSRRFHKTLRRLVPDSD 438 R+A++ +A L ++NR+R+++ +R TVGVDGS+YK HP + RFH ++RRL P + Sbjct: 375 TRAAHMCSAGLAGVINRMRESRSEDVMRITVGVDGSVYKLHPSFKERFHASVRRLTPSCE 434 Query: 439 VRFLLSESGSGKGAAMVTAVAYRLA 463 + F+ SE GSG+GAA+V+AVA + A Sbjct: 435 ITFIESEEGSGRGAALVSAVACKKA 459 >gi|4503951 glucokinase isoform 1 [Homo sapiens] Length = 465 Score = 504 bits (1298), Expect = e-142 Identities = 244/449 (54%), Positives = 334/449 (74%), Gaps = 2/449 (0%) Query: 463 AEQHRQIEETLAHFHLTKDMLLEVKKRMRAEMELGLRKQTHNNAVVKMLPSFVRRTPDGT 522 A + ++E+ LA F L ++ L +V +RM+ EM+ GLR +TH A VKMLP++VR TP+G+ Sbjct: 10 AAKKEKVEQILAEFQLQEEDLKKVMRRMQKEMDRGLRLETHEEASVKMLPTYVRSTPEGS 69 Query: 523 ENGDFLALDLGGTNFRVLLVKIRSGKKR--TVEMHNKIYAIPIEIMQGTGEELFDHIVSC 580 E GDFL+LDLGGTNFRV+LVK+ G++ +V+ +++Y+IP + M GT E LFD+I C Sbjct: 70 EVGDFLSLDLGGTNFRVMLVKVGEGEEGQWSVKTKHQMYSIPEDAMTGTAEMLFDYISEC 129 Query: 581 ISDFLDYMGIKGPRMPLGFTFSFPCQQTSLDAGILITWTKGFKATDCVGHDVVTLLRDAI 640 ISDFLD +K ++PLGFTFSFP + +D GIL+ WTKGFKA+ G++VV LLRDAI Sbjct: 130 ISDFLDKHQMKHKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGNNVVGLLRDAI 189 Query: 641 KRREEFDLDVVAVVNDTVGTMMTCAYEEPTCEVGLIVGTGSNACYMEEMKNVEMVEGDQG 700 KRR +F++DVVA+VNDTV TM++C YE+ CEVG+IVGTG NACYMEEM+NVE+VEGD+G Sbjct: 190 KRRGDFEMDVVAMVNDTVATMISCYYEDHQCEVGMIVGTGCNACYMEEMQNVELVEGDEG 249 Query: 701 QMCINMEWGAFGDNGCLDDIRTHYDRLVDEYSLNAGKQRYEKMISGMYLGEIVRNILIDF 760 +MC+N EWGAFGD+G LD+ YDRLVDE S N G+Q YEK+I G Y+GE+VR +L+ Sbjct: 250 RMCVNTEWGAFGDSGELDEFLLEYDRLVDESSANPGQQLYEKLIGGKYMGELVRLVLLRL 309 Query: 761 TKKGFLFRGQISETLKTRGIFETKFLSQIESDRLALLQVRAILQQLGLNSTCDDSILVKT 820 + LF G+ SE L+TRG FET+F+SQ+ESD Q+ IL LGL + D +V+ Sbjct: 310 VDENLLFHGEASEQLRTRGAFETRFVSQVESDTGDRKQIYNILSTLGLRPSTTDCDIVRR 369 Query: 821 VCGVVSRRAAQLCGAGMAAVVDKIRENRGLDRLNVTVGVDGTLYKLHPHFSRIMHQTVKE 880 C VS RAA +C AG+A V++++RE+R D + +TVGVDG++YKLHP F H +V+ Sbjct: 370 ACESVSTRAAHMCSAGLAGVINRMRESRSEDVMRITVGVDGSVYKLHPSFKERFHASVRR 429 Query: 881 LSPKCNVSFLLSEDGSGKGAALITAVGVR 909 L+P C ++F+ SE+GSG+GAAL++AV + Sbjct: 430 LTPSCEITFIESEEGSGRGAALVSAVACK 458 Score = 474 bits (1219), Expect = e-133 Identities = 222/445 (49%), Positives = 320/445 (71%), Gaps = 2/445 (0%) Query: 21 IDKYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEKGDFI 80 +++ L +L +E L +M R +KEM GL + + A+VKMLPT+VRS P+GSE GDF+ Sbjct: 16 VEQILAEFQLQEEDLKKVMRRMQKEMDRGLRLETHEEASVKMLPTYVRSTPEGSEVGDFL 75 Query: 81 ALDLGGSSFRILRVQVNH--EKNQNVHMESEVYDTPENIVHGSGSQLFDHVAECLGDFME 138 +LDLGG++FR++ V+V E +V + ++Y PE+ + G+ LFD+++EC+ DF++ Sbjct: 76 SLDLGGTNFRVMLVKVGEGEEGQWSVKTKHQMYSIPEDAMTGTAEMLFDYISECISDFLD 135 Query: 139 KRKIKDKKLPVGFTFSFPCQQSKIDEAILITWTKRFKASGVEGADVVKLLNKAIKKRGDY 198 K ++K KKLP+GFTFSFP + ID+ IL+ WTK FKASG EG +VV LL AIK+RGD+ Sbjct: 136 KHQMKHKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGNNVVGLLRDAIKRRGDF 195 Query: 199 DANIVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYMEELRHIDLVEGDEGRMCINT 258 + ++VA+VNDTV TM++C Y+D CEVG+I+GTG NACYMEE+++++LVEGDEGRMC+NT Sbjct: 196 EMDVVAMVNDTVATMISCYYEDHQCEVGMIVGTGCNACYMEEMQNVELVEGDEGRMCVNT 255 Query: 259 EWGAFGDDGSLEDIRTEFDREIDRGSLNPGKQLFEKMVSGMYLGELVRLILVKMAKEGLL 318 EWGAFGD G L++ E+DR +D S NPG+QL+EK++ G Y+GELVRL+L+++ E LL Sbjct: 256 EWGAFGDSGELDEFLLEYDRLVDESSANPGQQLYEKLIGGKYMGELVRLVLLRLVDENLL 315 Query: 319 FEGRITPELLTRGKFNTSDVSAIEKNKEGLHNAKEILTRLGVEPSDDDCVSVQHVCTIVS 378 F G + +L TRG F T VS +E + IL+ LG+ PS DC V+ C VS Sbjct: 316 FHGEASEQLRTRGAFETRFVSQVESDTGDRKQIYNILSTLGLRPSTTDCDIVRRACESVS 375 Query: 379 FRSANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKTHPQYSRRFHKTLRRLVPDSD 438 R+A++ +A L ++NR+R+++ +R TVGVDGS+YK HP + RFH ++RRL P + Sbjct: 376 TRAAHMCSAGLAGVINRMRESRSEDVMRITVGVDGSVYKLHPSFKERFHASVRRLTPSCE 435 Query: 439 VRFLLSESGSGKGAAMVTAVAYRLA 463 + F+ SE GSG+GAA+V+AVA + A Sbjct: 436 ITFIESEEGSGRGAALVSAVACKKA 460 >gi|15967159 glucokinase isoform 2 [Homo sapiens] Length = 466 Score = 503 bits (1294), Expect = e-142 Identities = 243/443 (54%), Positives = 331/443 (74%), Gaps = 2/443 (0%) Query: 469 IEETLAHFHLTKDMLLEVKKRMRAEMELGLRKQTHNNAVVKMLPSFVRRTPDGTENGDFL 528 +E+ LA F L ++ L +V +RM+ EM+ GLR +TH A VKMLP++VR TP+G+E GDFL Sbjct: 17 VEQILAEFQLQEEDLKKVMRRMQKEMDRGLRLETHEEASVKMLPTYVRSTPEGSEVGDFL 76 Query: 529 ALDLGGTNFRVLLVKIRSGKKR--TVEMHNKIYAIPIEIMQGTGEELFDHIVSCISDFLD 586 +LDLGGTNFRV+LVK+ G++ +V+ +++Y+IP + M GT E LFD+I CISDFLD Sbjct: 77 SLDLGGTNFRVMLVKVGEGEEGQWSVKTKHQMYSIPEDAMTGTAEMLFDYISECISDFLD 136 Query: 587 YMGIKGPRMPLGFTFSFPCQQTSLDAGILITWTKGFKATDCVGHDVVTLLRDAIKRREEF 646 +K ++PLGFTFSFP + +D GIL+ WTKGFKA+ G++VV LLRDAIKRR +F Sbjct: 137 KHQMKHKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGNNVVGLLRDAIKRRGDF 196 Query: 647 DLDVVAVVNDTVGTMMTCAYEEPTCEVGLIVGTGSNACYMEEMKNVEMVEGDQGQMCINM 706 ++DVVA+VNDTV TM++C YE+ CEVG+IVGTG NACYMEEM+NVE+VEGD+G+MC+N Sbjct: 197 EMDVVAMVNDTVATMISCYYEDHQCEVGMIVGTGCNACYMEEMQNVELVEGDEGRMCVNT 256 Query: 707 EWGAFGDNGCLDDIRTHYDRLVDEYSLNAGKQRYEKMISGMYLGEIVRNILIDFTKKGFL 766 EWGAFGD+G LD+ YDRLVDE S N G+Q YEK+I G Y+GE+VR +L+ + L Sbjct: 257 EWGAFGDSGELDEFLLEYDRLVDESSANPGQQLYEKLIGGKYMGELVRLVLLRLVDENLL 316 Query: 767 FRGQISETLKTRGIFETKFLSQIESDRLALLQVRAILQQLGLNSTCDDSILVKTVCGVVS 826 F G+ SE L+TRG FET+F+SQ+ESD Q+ IL LGL + D +V+ C VS Sbjct: 317 FHGEASEQLRTRGAFETRFVSQVESDTGDRKQIYNILSTLGLRPSTTDCDIVRRACESVS 376 Query: 827 RRAAQLCGAGMAAVVDKIRENRGLDRLNVTVGVDGTLYKLHPHFSRIMHQTVKELSPKCN 886 RAA +C AG+A V++++RE+R D + +TVGVDG++YKLHP F H +V+ L+P C Sbjct: 377 TRAAHMCSAGLAGVINRMRESRSEDVMRITVGVDGSVYKLHPSFKERFHASVRRLTPSCE 436 Query: 887 VSFLLSEDGSGKGAALITAVGVR 909 ++F+ SE+GSG+GAAL++AV + Sbjct: 437 ITFIESEEGSGRGAALVSAVACK 459 Score = 474 bits (1219), Expect = e-133 Identities = 222/445 (49%), Positives = 320/445 (71%), Gaps = 2/445 (0%) Query: 21 IDKYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEKGDFI 80 +++ L +L +E L +M R +KEM GL + + A+VKMLPT+VRS P+GSE GDF+ Sbjct: 17 VEQILAEFQLQEEDLKKVMRRMQKEMDRGLRLETHEEASVKMLPTYVRSTPEGSEVGDFL 76 Query: 81 ALDLGGSSFRILRVQVNH--EKNQNVHMESEVYDTPENIVHGSGSQLFDHVAECLGDFME 138 +LDLGG++FR++ V+V E +V + ++Y PE+ + G+ LFD+++EC+ DF++ Sbjct: 77 SLDLGGTNFRVMLVKVGEGEEGQWSVKTKHQMYSIPEDAMTGTAEMLFDYISECISDFLD 136 Query: 139 KRKIKDKKLPVGFTFSFPCQQSKIDEAILITWTKRFKASGVEGADVVKLLNKAIKKRGDY 198 K ++K KKLP+GFTFSFP + ID+ IL+ WTK FKASG EG +VV LL AIK+RGD+ Sbjct: 137 KHQMKHKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGNNVVGLLRDAIKRRGDF 196 Query: 199 DANIVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYMEELRHIDLVEGDEGRMCINT 258 + ++VA+VNDTV TM++C Y+D CEVG+I+GTG NACYMEE+++++LVEGDEGRMC+NT Sbjct: 197 EMDVVAMVNDTVATMISCYYEDHQCEVGMIVGTGCNACYMEEMQNVELVEGDEGRMCVNT 256 Query: 259 EWGAFGDDGSLEDIRTEFDREIDRGSLNPGKQLFEKMVSGMYLGELVRLILVKMAKEGLL 318 EWGAFGD G L++ E+DR +D S NPG+QL+EK++ G Y+GELVRL+L+++ E LL Sbjct: 257 EWGAFGDSGELDEFLLEYDRLVDESSANPGQQLYEKLIGGKYMGELVRLVLLRLVDENLL 316 Query: 319 FEGRITPELLTRGKFNTSDVSAIEKNKEGLHNAKEILTRLGVEPSDDDCVSVQHVCTIVS 378 F G + +L TRG F T VS +E + IL+ LG+ PS DC V+ C VS Sbjct: 317 FHGEASEQLRTRGAFETRFVSQVESDTGDRKQIYNILSTLGLRPSTTDCDIVRRACESVS 376 Query: 379 FRSANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKTHPQYSRRFHKTLRRLVPDSD 438 R+A++ +A L ++NR+R+++ +R TVGVDGS+YK HP + RFH ++RRL P + Sbjct: 377 TRAAHMCSAGLAGVINRMRESRSEDVMRITVGVDGSVYKLHPSFKERFHASVRRLTPSCE 436 Query: 439 VRFLLSESGSGKGAAMVTAVAYRLA 463 + F+ SE GSG+GAA+V+AVA + A Sbjct: 437 ITFIESEEGSGRGAALVSAVACKKA 461 >gi|164663810 ribosomal modification protein rimK-like family member A [Homo sapiens] Length = 391 Score = 34.7 bits (78), Expect = 0.42 Identities = 33/143 (23%), Positives = 59/143 (41%), Gaps = 30/143 (20%) Query: 577 IVSCISDFLDYMGIKGPRMPLGFTFSFPCQQT---------SLDAGILITWTKG------ 621 I++CI+ F + + G +P+ TFS+ + L +++ T+G Sbjct: 105 ILNCINKFWTFQELAGHGVPMPDTFSYGGHEDFSKMIDEAEPLGYPVVVKSTRGHRGKAV 164 Query: 622 FKATD---------CVGHDVVTLLRDAIKRREEFDLDVVAVVNDTVGTMMTCAYE---EP 669 F A D + HDV L + +K D+ VV V +G+M+ C+ + + Sbjct: 165 FLARDKHHLSDICHLIRHDVPYLFQKYVKESHGKDIRVVVVGGQVIGSMLRCSTDGRMQS 224 Query: 670 TCEVGLIVGTGSNACYMEEMKNV 692 C +G G G E+ K + Sbjct: 225 NCSLG---GVGVKCPLTEQGKQL 244 >gi|134254462 ribosomal modification protein rimK-like family member B [Homo sapiens] Length = 386 Score = 33.5 bits (75), Expect = 0.93 Identities = 41/191 (21%), Positives = 75/191 (39%), Gaps = 51/191 (26%) Query: 577 IVSCISDFLDYMGIKGPRMPLGFTFSFPCQQT---------SLDAGILITWTKG------ 621 I++C++ F + + G +PL TFS+ + L+ +++ T+G Sbjct: 109 ILNCVNKFWTFQELAGHGVPLPDTFSYGGHENFAKMIDEAEVLEFPMVVKNTRGHRGKAV 168 Query: 622 FKATD---------CVGHDVVTLLRDAIKRREEFDLDVVAVVNDTVGTMMTCAYE---EP 669 F A D + H+ L + +K D+ V+ V VGTM+ C+ + + Sbjct: 169 FLARDKHHLADLSHLIRHEAPYLFQKYVKESHGRDVRVIVVGGRVVGTMLRCSTDGRMQS 228 Query: 670 TCEVGLIVGTGSNACYMEEMK---------------NVEMVEGDQGQMCI-----NMEWG 709 C +G G G E+ K ++++ D G C+ N+ + Sbjct: 229 NCSLG---GVGMMCSLSEQGKQLAIQVSNILGMDVCGIDLLMKDDGSFCVCEANANVGFI 285 Query: 710 AFGDNGCLDDI 720 AF D C D+ Sbjct: 286 AF-DKACNLDV 295 >gi|21389509 KPL2 protein isoform 2 [Homo sapiens] Length = 514 Score = 32.0 bits (71), Expect = 2.7 Identities = 17/76 (22%), Positives = 37/76 (48%), Gaps = 2/76 (2%) Query: 458 VAYRLAEQHRQIEETLAHFHLTK-DMLLEVKKRMRA-EMELGLRKQTHNNAVVKMLPSFV 515 + YR E+++ ++E LAH H K + ++K+ R ++E + N ++ + + + Sbjct: 155 ITYRFQEKYKHVKEDLAHLHFEKLERFQKLKEEQRCFDIEKQYLNRRRQNEIMAKIQAAI 214 Query: 516 RRTPDGTENGDFLALD 531 + P N AL+ Sbjct: 215 IQIPKPASNRTLKALE 230 >gi|145699133 KPL2 protein isoform 1 [Homo sapiens] Length = 1822 Score = 32.0 bits (71), Expect = 2.7 Identities = 17/76 (22%), Positives = 37/76 (48%), Gaps = 2/76 (2%) Query: 458 VAYRLAEQHRQIEETLAHFHLTK-DMLLEVKKRMRA-EMELGLRKQTHNNAVVKMLPSFV 515 + YR E+++ ++E LAH H K + ++K+ R ++E + N ++ + + + Sbjct: 155 ITYRFQEKYKHVKEDLAHLHFEKLERFQKLKEEQRCFDIEKQYLNRRRQNEIMAKIQAAI 214 Query: 516 RRTPDGTENGDFLALD 531 + P N AL+ Sbjct: 215 IQIPKPASNRTLKALE 230 >gi|42415492 chromosome 14 open reading frame 106 [Homo sapiens] Length = 1132 Score = 30.4 bits (67), Expect = 7.9 Identities = 23/77 (29%), Positives = 37/77 (48%), Gaps = 4/77 (5%) Query: 276 FDREIDRGSLNPGKQLFEKMVSGMYLGELVRLILVKMA--KEGLLFEGRITPELLTRGKF 333 F I G+L P K L + S + L + + +KM +F+ + E T Sbjct: 30 FFDSIPSGTLTPVKDLVKYQNSSLKLNDHKKNQFLKMTTFNNKNIFQSTMLTEATTSN-- 87 Query: 334 NTSDVSAIEKNKEGLHN 350 ++ D+SAI+ NK+GL N Sbjct: 88 SSLDISAIKPNKDGLKN 104 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.321 0.137 0.403 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 32,436,444 Number of Sequences: 37866 Number of extensions: 1408811 Number of successful extensions: 2748 Number of sequences better than 10.0: 16 Number of HSP's better than 10.0 without gapping: 11 Number of HSP's successfully gapped in prelim test: 5 Number of HSP's that attempted gapping in prelim test: 2703 Number of HSP's gapped (non-prelim): 28 length of query: 916 length of database: 18,247,518 effective HSP length: 111 effective length of query: 805 effective length of database: 14,044,392 effective search space: 11305735560 effective search space used: 11305735560 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.