Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 15967161
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|15967161 glucokinase isoform 3 [Homo sapiens]
(464 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|15967161 glucokinase isoform 3 [Homo sapiens] 932 0.0
gi|15967159 glucokinase isoform 2 [Homo sapiens] 905 0.0
gi|4503951 glucokinase isoform 1 [Homo sapiens] 903 0.0
gi|15553127 hexokinase 2 [Homo sapiens] 518 e-147
gi|188497750 hexokinase 1 isoform HKI-td [Homo sapiens] 506 e-143
gi|188497754 hexokinase 1 isoform HKI [Homo sapiens] 506 e-143
gi|15991829 hexokinase 1 isoform HKI-ta/tb [Homo sapiens] 506 e-143
gi|15991831 hexokinase 1 isoform HKI-ta/tb [Homo sapiens] 506 e-143
gi|15991827 hexokinase 1 isoform HKI-R [Homo sapiens] 506 e-143
gi|156151420 hexokinase domain containing 1 [Homo sapiens] 494 e-140
gi|194097330 hexokinase 3 [Homo sapiens] 473 e-133
gi|22027525 Rac/Cdc42 guanine nucleotide exchange factor 6 [Homo... 34 0.32
gi|241982780 programmed cell death 6 interacting protein isoform... 30 4.6
gi|22027538 programmed cell death 6 interacting protein isoform ... 30 4.6
gi|153791497 ciliary rootlet coiled-coil [Homo sapiens] 30 4.6
gi|81295816 nasopharyngeal epithelium specific protein 1 [Homo s... 30 4.6
gi|53832011 calcium channel, voltage-dependent, T type, alpha 1H... 30 6.1
gi|53832009 calcium channel, voltage-dependent, T type, alpha 1H... 30 6.1
gi|4502443 dystonin isoform 1e precursor [Homo sapiens] 30 6.1
gi|160948610 E3 ubiquitin-protein ligase UBR3 [Homo sapiens] 30 6.1
gi|63055059 SH3 and PX domains 2B [Homo sapiens] 29 7.9
gi|117414143 hypothetical protein LOC55603 [Homo sapiens] 29 7.9
>gi|15967161 glucokinase isoform 3 [Homo sapiens]
Length = 464
Score = 932 bits (2408), Expect = 0.0
Identities = 464/464 (100%), Positives = 464/464 (100%)
Query: 1 MPRPRSQLPQPNSQVEQILAEFQLQEEDLKKVMRRMQKEMDRGLRLETHEEASVKMLPTY 60
MPRPRSQLPQPNSQVEQILAEFQLQEEDLKKVMRRMQKEMDRGLRLETHEEASVKMLPTY
Sbjct: 1 MPRPRSQLPQPNSQVEQILAEFQLQEEDLKKVMRRMQKEMDRGLRLETHEEASVKMLPTY 60
Query: 61 VRSTPEGSEVGDFLSLDLGGTNFRVMLVKVGEGEEGQWSVKTKHQMYSIPEDAMTGTAEM 120
VRSTPEGSEVGDFLSLDLGGTNFRVMLVKVGEGEEGQWSVKTKHQMYSIPEDAMTGTAEM
Sbjct: 61 VRSTPEGSEVGDFLSLDLGGTNFRVMLVKVGEGEEGQWSVKTKHQMYSIPEDAMTGTAEM 120
Query: 121 LFDYISECISDFLDKHQMKHKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGNNV 180
LFDYISECISDFLDKHQMKHKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGNNV
Sbjct: 121 LFDYISECISDFLDKHQMKHKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGNNV 180
Query: 181 VGLLRDAIKRRGDFEMDVVAMVNDTVATMISCYYEDHQCEVGMIVGTGCNACYMEEMQNV 240
VGLLRDAIKRRGDFEMDVVAMVNDTVATMISCYYEDHQCEVGMIVGTGCNACYMEEMQNV
Sbjct: 181 VGLLRDAIKRRGDFEMDVVAMVNDTVATMISCYYEDHQCEVGMIVGTGCNACYMEEMQNV 240
Query: 241 ELVEGDEGRMCVNTEWGAFGDSGELDEFLLEYDRLVDESSANPGQQLYEKLIGGKYMGEL 300
ELVEGDEGRMCVNTEWGAFGDSGELDEFLLEYDRLVDESSANPGQQLYEKLIGGKYMGEL
Sbjct: 241 ELVEGDEGRMCVNTEWGAFGDSGELDEFLLEYDRLVDESSANPGQQLYEKLIGGKYMGEL 300
Query: 301 VRLVLLRLVDENLLFHGEASEQLRTRGAFETRFVSQVESDTGDRKQIYNILSTLGLRPST 360
VRLVLLRLVDENLLFHGEASEQLRTRGAFETRFVSQVESDTGDRKQIYNILSTLGLRPST
Sbjct: 301 VRLVLLRLVDENLLFHGEASEQLRTRGAFETRFVSQVESDTGDRKQIYNILSTLGLRPST 360
Query: 361 TDCDIVRRACESVSTRAAHMCSAGLAGVINRMRESRSEDVMRITVGVDGSVYKLHPSFKE 420
TDCDIVRRACESVSTRAAHMCSAGLAGVINRMRESRSEDVMRITVGVDGSVYKLHPSFKE
Sbjct: 361 TDCDIVRRACESVSTRAAHMCSAGLAGVINRMRESRSEDVMRITVGVDGSVYKLHPSFKE 420
Query: 421 RFHASVRRLTPSCEITFIESEEGSGRGAALVSAVACKKACMLGQ 464
RFHASVRRLTPSCEITFIESEEGSGRGAALVSAVACKKACMLGQ
Sbjct: 421 RFHASVRRLTPSCEITFIESEEGSGRGAALVSAVACKKACMLGQ 464
>gi|15967159 glucokinase isoform 2 [Homo sapiens]
Length = 466
Score = 905 bits (2338), Expect = 0.0
Identities = 453/460 (98%), Positives = 454/460 (98%)
Query: 5 RSQLPQPNSQVEQILAEFQLQEEDLKKVMRRMQKEMDRGLRLETHEEASVKMLPTYVRST 64
RSQ + VEQILAEFQLQEEDLKKVMRRMQKEMDRGLRLETHEEASVKMLPTYVRST
Sbjct: 7 RSQAQTALTLVEQILAEFQLQEEDLKKVMRRMQKEMDRGLRLETHEEASVKMLPTYVRST 66
Query: 65 PEGSEVGDFLSLDLGGTNFRVMLVKVGEGEEGQWSVKTKHQMYSIPEDAMTGTAEMLFDY 124
PEGSEVGDFLSLDLGGTNFRVMLVKVGEGEEGQWSVKTKHQMYSIPEDAMTGTAEMLFDY
Sbjct: 67 PEGSEVGDFLSLDLGGTNFRVMLVKVGEGEEGQWSVKTKHQMYSIPEDAMTGTAEMLFDY 126
Query: 125 ISECISDFLDKHQMKHKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGNNVVGLL 184
ISECISDFLDKHQMKHKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGNNVVGLL
Sbjct: 127 ISECISDFLDKHQMKHKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGNNVVGLL 186
Query: 185 RDAIKRRGDFEMDVVAMVNDTVATMISCYYEDHQCEVGMIVGTGCNACYMEEMQNVELVE 244
RDAIKRRGDFEMDVVAMVNDTVATMISCYYEDHQCEVGMIVGTGCNACYMEEMQNVELVE
Sbjct: 187 RDAIKRRGDFEMDVVAMVNDTVATMISCYYEDHQCEVGMIVGTGCNACYMEEMQNVELVE 246
Query: 245 GDEGRMCVNTEWGAFGDSGELDEFLLEYDRLVDESSANPGQQLYEKLIGGKYMGELVRLV 304
GDEGRMCVNTEWGAFGDSGELDEFLLEYDRLVDESSANPGQQLYEKLIGGKYMGELVRLV
Sbjct: 247 GDEGRMCVNTEWGAFGDSGELDEFLLEYDRLVDESSANPGQQLYEKLIGGKYMGELVRLV 306
Query: 305 LLRLVDENLLFHGEASEQLRTRGAFETRFVSQVESDTGDRKQIYNILSTLGLRPSTTDCD 364
LLRLVDENLLFHGEASEQLRTRGAFETRFVSQVESDTGDRKQIYNILSTLGLRPSTTDCD
Sbjct: 307 LLRLVDENLLFHGEASEQLRTRGAFETRFVSQVESDTGDRKQIYNILSTLGLRPSTTDCD 366
Query: 365 IVRRACESVSTRAAHMCSAGLAGVINRMRESRSEDVMRITVGVDGSVYKLHPSFKERFHA 424
IVRRACESVSTRAAHMCSAGLAGVINRMRESRSEDVMRITVGVDGSVYKLHPSFKERFHA
Sbjct: 367 IVRRACESVSTRAAHMCSAGLAGVINRMRESRSEDVMRITVGVDGSVYKLHPSFKERFHA 426
Query: 425 SVRRLTPSCEITFIESEEGSGRGAALVSAVACKKACMLGQ 464
SVRRLTPSCEITFIESEEGSGRGAALVSAVACKKACMLGQ
Sbjct: 427 SVRRLTPSCEITFIESEEGSGRGAALVSAVACKKACMLGQ 466
>gi|4503951 glucokinase isoform 1 [Homo sapiens]
Length = 465
Score = 903 bits (2333), Expect = 0.0
Identities = 450/451 (99%), Positives = 451/451 (100%)
Query: 14 QVEQILAEFQLQEEDLKKVMRRMQKEMDRGLRLETHEEASVKMLPTYVRSTPEGSEVGDF 73
+VEQILAEFQLQEEDLKKVMRRMQKEMDRGLRLETHEEASVKMLPTYVRSTPEGSEVGDF
Sbjct: 15 KVEQILAEFQLQEEDLKKVMRRMQKEMDRGLRLETHEEASVKMLPTYVRSTPEGSEVGDF 74
Query: 74 LSLDLGGTNFRVMLVKVGEGEEGQWSVKTKHQMYSIPEDAMTGTAEMLFDYISECISDFL 133
LSLDLGGTNFRVMLVKVGEGEEGQWSVKTKHQMYSIPEDAMTGTAEMLFDYISECISDFL
Sbjct: 75 LSLDLGGTNFRVMLVKVGEGEEGQWSVKTKHQMYSIPEDAMTGTAEMLFDYISECISDFL 134
Query: 134 DKHQMKHKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGNNVVGLLRDAIKRRGD 193
DKHQMKHKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGNNVVGLLRDAIKRRGD
Sbjct: 135 DKHQMKHKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGNNVVGLLRDAIKRRGD 194
Query: 194 FEMDVVAMVNDTVATMISCYYEDHQCEVGMIVGTGCNACYMEEMQNVELVEGDEGRMCVN 253
FEMDVVAMVNDTVATMISCYYEDHQCEVGMIVGTGCNACYMEEMQNVELVEGDEGRMCVN
Sbjct: 195 FEMDVVAMVNDTVATMISCYYEDHQCEVGMIVGTGCNACYMEEMQNVELVEGDEGRMCVN 254
Query: 254 TEWGAFGDSGELDEFLLEYDRLVDESSANPGQQLYEKLIGGKYMGELVRLVLLRLVDENL 313
TEWGAFGDSGELDEFLLEYDRLVDESSANPGQQLYEKLIGGKYMGELVRLVLLRLVDENL
Sbjct: 255 TEWGAFGDSGELDEFLLEYDRLVDESSANPGQQLYEKLIGGKYMGELVRLVLLRLVDENL 314
Query: 314 LFHGEASEQLRTRGAFETRFVSQVESDTGDRKQIYNILSTLGLRPSTTDCDIVRRACESV 373
LFHGEASEQLRTRGAFETRFVSQVESDTGDRKQIYNILSTLGLRPSTTDCDIVRRACESV
Sbjct: 315 LFHGEASEQLRTRGAFETRFVSQVESDTGDRKQIYNILSTLGLRPSTTDCDIVRRACESV 374
Query: 374 STRAAHMCSAGLAGVINRMRESRSEDVMRITVGVDGSVYKLHPSFKERFHASVRRLTPSC 433
STRAAHMCSAGLAGVINRMRESRSEDVMRITVGVDGSVYKLHPSFKERFHASVRRLTPSC
Sbjct: 375 STRAAHMCSAGLAGVINRMRESRSEDVMRITVGVDGSVYKLHPSFKERFHASVRRLTPSC 434
Query: 434 EITFIESEEGSGRGAALVSAVACKKACMLGQ 464
EITFIESEEGSGRGAALVSAVACKKACMLGQ
Sbjct: 435 EITFIESEEGSGRGAALVSAVACKKACMLGQ 465
>gi|15553127 hexokinase 2 [Homo sapiens]
Length = 917
Score = 518 bits (1334), Expect = e-147
Identities = 241/446 (54%), Positives = 339/446 (76%), Gaps = 2/446 (0%)
Query: 14 QVEQILAEFQLQEEDLKKVMRRMQKEMDRGLRLETHEEASVKMLPTYVRSTPEGSEVGDF 73
+V+Q L +L +E L ++ +R +KEM++GL TH A+VKMLPT+VRSTP+G+E G+F
Sbjct: 21 KVDQYLYHMRLSDETLLEISKRFRKEMEKGLGATTHPTAAVKMLPTFVRSTPDGTEHGEF 80
Query: 74 LSLDLGGTNFRVMLVKVGEGEEGQWSVKTKHQMYSIPEDAMTGTAEMLFDYISECISDFL 133
L+LDLGGTNFRV+ VKV + G V+ ++Q+Y+IPED M G+ LFD+I+EC+++F+
Sbjct: 81 LALDLGGTNFRVLWVKVTDN--GLQKVEMENQIYAIPEDIMRGSGTQLFDHIAECLANFM 138
Query: 134 DKHQMKHKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGNNVVGLLRDAIKRRGD 193
DK Q+K KKLPLGFTFSFP +D+ L++WTKGFK+SG EG +VV L+R AI+RRGD
Sbjct: 139 DKLQIKDKKLPLGFTFSFPCHQTKLDESFLVSWTKGFKSSGVEGRDVVALIRKAIQRRGD 198
Query: 194 FEMDVVAMVNDTVATMISCYYEDHQCEVGMIVGTGCNACYMEEMQNVELVEGDEGRMCVN 253
F++D+VA+VNDTV TM++C Y+DH CE+G+IVGTG NACYMEEM+++++VEGDEGRMC+N
Sbjct: 199 FDIDIVAVVNDTVGTMMTCGYDDHNCEIGLIVGTGSNACYMEEMRHIDMVEGDEGRMCIN 258
Query: 254 TEWGAFGDSGELDEFLLEYDRLVDESSANPGQQLYEKLIGGKYMGELVRLVLLRLVDENL 313
EWGAFGD G L++ E+D+ +D S NPG+QL+EK+I G YMGELVRL+L+++ E L
Sbjct: 259 MEWGAFGDDGSLNDIRTEFDQEIDMGSLNPGKQLFEKMISGMYMGELVRLILVKMAKEEL 318
Query: 314 LFHGEASEQLRTRGAFETRFVSQVESDTGDRKQIYNILSTLGLRPSTTDCDIVRRACESV 373
LF G+ S +L G FET+ +S +E + ++ +L LGL P+ DC R C+ V
Sbjct: 319 LFGGKLSPELLNTGRFETKDISDIEGEKDGIRKAREVLMRLGLDPTQEDCVATHRICQIV 378
Query: 374 STRAAHMCSAGLAGVINRMRESRSEDVMRITVGVDGSVYKLHPSFKERFHASVRRLTPSC 433
STR+A +C+A LA V+ R++E++ E+ +R T+GVDGSVYK HP F +R H +VRRL P C
Sbjct: 379 STRSASLCAATLAAVLQRIKENKGEERLRSTIGVDGSVYKKHPHFAKRLHKTVRRLVPGC 438
Query: 434 EITFIESEEGSGRGAALVSAVACKKA 459
++ F+ SE+GSG+GAA+V+AVA + A
Sbjct: 439 DVRFLRSEDGSGKGAAMVTAVAYRLA 464
Score = 516 bits (1329), Expect = e-146
Identities = 250/442 (56%), Positives = 334/442 (75%), Gaps = 2/442 (0%)
Query: 16 EQILAEFQLQEEDLKKVMRRMQKEMDRGLRLETHEEASVKMLPTYVRSTPEGSEVGDFLS 75
++ L QL + L +V RRM+ EM+RGL ETH A VKMLPTYV +TP+G+E GDFL+
Sbjct: 471 QKTLEHLQLSHDQLLEVKRRMKVEMERGLSKETHASAPVKMLPTYVCATPDGTEKGDFLA 530
Query: 76 LDLGGTNFRVMLVKVGEGEEGQWSVKTKHQMYSIPEDAMTGTAEMLFDYISECISDFLDK 135
LDLGGTNFRV+LV+V G+ G V+ +++Y+IP++ M GT + LFD+I +CI+DFL+
Sbjct: 531 LDLGGTNFRVLLVRVRNGKWG--GVEMHNKIYAIPQEVMHGTGDELFDHIVQCIADFLEY 588
Query: 136 HQMKHKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGNNVVGLLRDAIKRRGDFE 195
MK LPLGFTFSFP + +D+ ILL WTKGFKASG EG +VV LL++AI RR +F+
Sbjct: 589 MGMKGVSLPLGFTFSFPCQQNSLDESILLKWTKGFKASGCEGEDVVTLLKEAIHRREEFD 648
Query: 196 MDVVAMVNDTVATMISCYYEDHQCEVGMIVGTGCNACYMEEMQNVELVEGDEGRMCVNTE 255
+DVVA+VNDTV TM++C +ED CEVG+IVGTG NACYMEEM+NVELVEG+EGRMCVN E
Sbjct: 649 LDVVAVVNDTVGTMMTCGFEDPHCEVGLIVGTGSNACYMEEMRNVELVEGEEGRMCVNME 708
Query: 256 WGAFGDSGELDEFLLEYDRLVDESSANPGQQLYEKLIGGKYMGELVRLVLLRLVDENLLF 315
WGAFGD+G LD+F E+D VDE S NPG+Q +EK+I G Y+GE+VR +L+ LLF
Sbjct: 709 WGAFGDNGCLDDFRTEFDVAVDELSLNPGKQRFEKMISGMYLGEIVRNILIDFTKRGLLF 768
Query: 316 HGEASEQLRTRGAFETRFVSQVESDTGDRKQIYNILSTLGLRPSTTDCDIVRRACESVST 375
G SE+L+TRG FET+F+SQ+ESD Q+ IL LGL + D IV+ C V+
Sbjct: 769 RGRISERLKTRGIFETKFLSQIESDCLALLQVRAILQHLGLESTCDDSIIVKEVCTVVAR 828
Query: 376 RAAHMCSAGLAGVINRMRESRSEDVMRITVGVDGSVYKLHPSFKERFHASVRRLTPSCEI 435
RAA +C AG+A V++R+RE+R D +++TVGVDG++YKLHP F + H +V+ L P C++
Sbjct: 829 RAAQLCGAGMAAVVDRIRENRGLDALKVTVGVDGTLYKLHPHFAKVMHETVKDLAPKCDV 888
Query: 436 TFIESEEGSGRGAALVSAVACK 457
+F++SE+GSG+GAAL++AVAC+
Sbjct: 889 SFLQSEDGSGKGAALITAVACR 910
>gi|188497750 hexokinase 1 isoform HKI-td [Homo sapiens]
Length = 905
Score = 506 bits (1304), Expect = e-143
Identities = 245/451 (54%), Positives = 336/451 (74%), Gaps = 2/451 (0%)
Query: 7 QLPQPNSQVEQILAEFQLQEEDLKKVMRRMQKEMDRGLRLETHEEASVKMLPTYVRSTPE 66
+L + + Q+E+ LA F L ++ L +V +RM+ EM+ GLR +TH A VKMLP++VR TP+
Sbjct: 450 RLAEQHRQIEETLAHFHLTKDMLLEVKKRMRAEMELGLRKQTHNNAVVKMLPSFVRRTPD 509
Query: 67 GSEVGDFLSLDLGGTNFRVMLVKVGEGEEGQWSVKTKHQMYSIPEDAMTGTAEMLFDYIS 126
G+E GDFL+LDLGGTNFRV+LVK+ G++ +V+ +++Y+IP + M GT E LFD+I
Sbjct: 510 GTENGDFLALDLGGTNFRVLLVKIRSGKKR--TVEMHNKIYAIPIEIMQGTGEELFDHIV 567
Query: 127 ECISDFLDKHQMKHKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGNNVVGLLRD 186
CISDFLD +K ++PLGFTFSFP + +D GIL+ WTKGFKA+ G++VV LLRD
Sbjct: 568 SCISDFLDYMGIKGPRMPLGFTFSFPCQQTSLDAGILITWTKGFKATDCVGHDVVTLLRD 627
Query: 187 AIKRRGDFEMDVVAMVNDTVATMISCYYEDHQCEVGMIVGTGCNACYMEEMQNVELVEGD 246
AIKRR +F++DVVA+VNDTV TM++C YE+ CEVG+IVGTG NACYMEEM+NVE+VEGD
Sbjct: 628 AIKRREEFDLDVVAVVNDTVGTMMTCAYEEPTCEVGLIVGTGSNACYMEEMKNVEMVEGD 687
Query: 247 EGRMCVNTEWGAFGDSGELDEFLLEYDRLVDESSANPGQQLYEKLIGGKYMGELVRLVLL 306
+G+MC+N EWGAFGD+G LD+ YDRLVDE S N G+Q YEK+I G Y+GE+VR +L+
Sbjct: 688 QGQMCINMEWGAFGDNGCLDDIRTHYDRLVDEYSLNAGKQRYEKMISGMYLGEIVRNILI 747
Query: 307 RLVDENLLFHGEASEQLRTRGAFETRFVSQVESDTGDRKQIYNILSTLGLRPSTTDCDIV 366
+ LF G+ SE L+TRG FET+F+SQ+ESD Q+ IL LGL + D +V
Sbjct: 748 DFTKKGFLFRGQISETLKTRGIFETKFLSQIESDRLALLQVRAILQQLGLNSTCDDSILV 807
Query: 367 RRACESVSTRAAHMCSAGLAGVINRMRESRSEDVMRITVGVDGSVYKLHPSFKERFHASV 426
+ C VS RAA +C AG+A V++++RE+R D + +TVGVDG++YKLHP F H +V
Sbjct: 808 KTVCGVVSRRAAQLCGAGMAAVVDKIRENRGLDRLNVTVGVDGTLYKLHPHFSRIMHQTV 867
Query: 427 RRLTPSCEITFIESEEGSGRGAALVSAVACK 457
+ L+P C ++F+ SE+GSG+GAAL++AV +
Sbjct: 868 KELSPKCNVSFLLSEDGSGKGAALITAVGVR 898
Score = 474 bits (1219), Expect = e-134
Identities = 222/445 (49%), Positives = 320/445 (71%), Gaps = 2/445 (0%)
Query: 15 VEQILAEFQLQEEDLKKVMRRMQKEMDRGLRLETHEEASVKMLPTYVRSTPEGSEVGDFL 74
+++ L +L +E L +M R +KEM GL + + A+VKMLPT+VRS P+GSE GDF+
Sbjct: 10 IDKYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEKGDFI 69
Query: 75 SLDLGGTNFRVMLVKVGEGEEGQWSVKTKHQMYSIPEDAMTGTAEMLFDYISECISDFLD 134
+LDLGG++FR++ V+V E +V + ++Y PE+ + G+ LFD+++EC+ DF++
Sbjct: 70 ALDLGGSSFRILRVQVNH--EKNQNVHMESEVYDTPENIVHGSGSQLFDHVAECLGDFME 127
Query: 135 KHQMKHKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGNNVVGLLRDAIKRRGDF 194
K ++K KKLP+GFTFSFP + ID+ IL+ WTK FKASG EG +VV LL AIK+RGD+
Sbjct: 128 KRKIKDKKLPVGFTFSFPCQQSKIDEAILITWTKRFKASGVEGADVVKLLNKAIKKRGDY 187
Query: 195 EMDVVAMVNDTVATMISCYYEDHQCEVGMIVGTGCNACYMEEMQNVELVEGDEGRMCVNT 254
+ ++VA+VNDTV TM++C Y+D CEVG+I+GTG NACYMEE+++++LVEGDEGRMC+NT
Sbjct: 188 DANIVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYMEELRHIDLVEGDEGRMCINT 247
Query: 255 EWGAFGDSGELDEFLLEYDRLVDESSANPGQQLYEKLIGGKYMGELVRLVLLRLVDENLL 314
EWGAFGD G L++ E+DR +D S NPG+QL+EK++ G Y+GELVRL+L+++ E LL
Sbjct: 248 EWGAFGDDGSLEDIRTEFDREIDRGSLNPGKQLFEKMVSGMYLGELVRLILVKMAKEGLL 307
Query: 315 FHGEASEQLRTRGAFETRFVSQVESDTGDRKQIYNILSTLGLRPSTTDCDIVRRACESVS 374
F G + +L TRG F T VS +E + IL+ LG+ PS DC V+ C VS
Sbjct: 308 FEGRITPELLTRGKFNTSDVSAIEKNKEGLHNAKEILTRLGVEPSDDDCVSVQHVCTIVS 367
Query: 375 TRAAHMCSAGLAGVINRMRESRSEDVMRITVGVDGSVYKLHPSFKERFHASVRRLTPSCE 434
R+A++ +A L ++NR+R+++ +R TVGVDGS+YK HP + RFH ++RRL P +
Sbjct: 368 FRSANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKTHPQYSRRFHKTLRRLVPDSD 427
Query: 435 ITFIESEEGSGRGAALVSAVACKKA 459
+ F+ SE GSG+GAA+V+AVA + A
Sbjct: 428 VRFLLSESGSGKGAAMVTAVAYRLA 452
>gi|188497754 hexokinase 1 isoform HKI [Homo sapiens]
Length = 917
Score = 506 bits (1304), Expect = e-143
Identities = 245/451 (54%), Positives = 336/451 (74%), Gaps = 2/451 (0%)
Query: 7 QLPQPNSQVEQILAEFQLQEEDLKKVMRRMQKEMDRGLRLETHEEASVKMLPTYVRSTPE 66
+L + + Q+E+ LA F L ++ L +V +RM+ EM+ GLR +TH A VKMLP++VR TP+
Sbjct: 462 RLAEQHRQIEETLAHFHLTKDMLLEVKKRMRAEMELGLRKQTHNNAVVKMLPSFVRRTPD 521
Query: 67 GSEVGDFLSLDLGGTNFRVMLVKVGEGEEGQWSVKTKHQMYSIPEDAMTGTAEMLFDYIS 126
G+E GDFL+LDLGGTNFRV+LVK+ G++ +V+ +++Y+IP + M GT E LFD+I
Sbjct: 522 GTENGDFLALDLGGTNFRVLLVKIRSGKKR--TVEMHNKIYAIPIEIMQGTGEELFDHIV 579
Query: 127 ECISDFLDKHQMKHKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGNNVVGLLRD 186
CISDFLD +K ++PLGFTFSFP + +D GIL+ WTKGFKA+ G++VV LLRD
Sbjct: 580 SCISDFLDYMGIKGPRMPLGFTFSFPCQQTSLDAGILITWTKGFKATDCVGHDVVTLLRD 639
Query: 187 AIKRRGDFEMDVVAMVNDTVATMISCYYEDHQCEVGMIVGTGCNACYMEEMQNVELVEGD 246
AIKRR +F++DVVA+VNDTV TM++C YE+ CEVG+IVGTG NACYMEEM+NVE+VEGD
Sbjct: 640 AIKRREEFDLDVVAVVNDTVGTMMTCAYEEPTCEVGLIVGTGSNACYMEEMKNVEMVEGD 699
Query: 247 EGRMCVNTEWGAFGDSGELDEFLLEYDRLVDESSANPGQQLYEKLIGGKYMGELVRLVLL 306
+G+MC+N EWGAFGD+G LD+ YDRLVDE S N G+Q YEK+I G Y+GE+VR +L+
Sbjct: 700 QGQMCINMEWGAFGDNGCLDDIRTHYDRLVDEYSLNAGKQRYEKMISGMYLGEIVRNILI 759
Query: 307 RLVDENLLFHGEASEQLRTRGAFETRFVSQVESDTGDRKQIYNILSTLGLRPSTTDCDIV 366
+ LF G+ SE L+TRG FET+F+SQ+ESD Q+ IL LGL + D +V
Sbjct: 760 DFTKKGFLFRGQISETLKTRGIFETKFLSQIESDRLALLQVRAILQQLGLNSTCDDSILV 819
Query: 367 RRACESVSTRAAHMCSAGLAGVINRMRESRSEDVMRITVGVDGSVYKLHPSFKERFHASV 426
+ C VS RAA +C AG+A V++++RE+R D + +TVGVDG++YKLHP F H +V
Sbjct: 820 KTVCGVVSRRAAQLCGAGMAAVVDKIRENRGLDRLNVTVGVDGTLYKLHPHFSRIMHQTV 879
Query: 427 RRLTPSCEITFIESEEGSGRGAALVSAVACK 457
+ L+P C ++F+ SE+GSG+GAAL++AV +
Sbjct: 880 KELSPKCNVSFLLSEDGSGKGAALITAVGVR 910
Score = 474 bits (1220), Expect = e-134
Identities = 222/446 (49%), Positives = 321/446 (71%), Gaps = 2/446 (0%)
Query: 14 QVEQILAEFQLQEEDLKKVMRRMQKEMDRGLRLETHEEASVKMLPTYVRSTPEGSEVGDF 73
++++ L +L +E L +M R +KEM GL + + A+VKMLPT+VRS P+GSE GDF
Sbjct: 21 KIDKYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEKGDF 80
Query: 74 LSLDLGGTNFRVMLVKVGEGEEGQWSVKTKHQMYSIPEDAMTGTAEMLFDYISECISDFL 133
++LDLGG++FR++ V+V E +V + ++Y PE+ + G+ LFD+++EC+ DF+
Sbjct: 81 IALDLGGSSFRILRVQVNH--EKNQNVHMESEVYDTPENIVHGSGSQLFDHVAECLGDFM 138
Query: 134 DKHQMKHKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGNNVVGLLRDAIKRRGD 193
+K ++K KKLP+GFTFSFP + ID+ IL+ WTK FKASG EG +VV LL AIK+RGD
Sbjct: 139 EKRKIKDKKLPVGFTFSFPCQQSKIDEAILITWTKRFKASGVEGADVVKLLNKAIKKRGD 198
Query: 194 FEMDVVAMVNDTVATMISCYYEDHQCEVGMIVGTGCNACYMEEMQNVELVEGDEGRMCVN 253
++ ++VA+VNDTV TM++C Y+D CEVG+I+GTG NACYMEE+++++LVEGDEGRMC+N
Sbjct: 199 YDANIVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYMEELRHIDLVEGDEGRMCIN 258
Query: 254 TEWGAFGDSGELDEFLLEYDRLVDESSANPGQQLYEKLIGGKYMGELVRLVLLRLVDENL 313
TEWGAFGD G L++ E+DR +D S NPG+QL+EK++ G Y+GELVRL+L+++ E L
Sbjct: 259 TEWGAFGDDGSLEDIRTEFDREIDRGSLNPGKQLFEKMVSGMYLGELVRLILVKMAKEGL 318
Query: 314 LFHGEASEQLRTRGAFETRFVSQVESDTGDRKQIYNILSTLGLRPSTTDCDIVRRACESV 373
LF G + +L TRG F T VS +E + IL+ LG+ PS DC V+ C V
Sbjct: 319 LFEGRITPELLTRGKFNTSDVSAIEKNKEGLHNAKEILTRLGVEPSDDDCVSVQHVCTIV 378
Query: 374 STRAAHMCSAGLAGVINRMRESRSEDVMRITVGVDGSVYKLHPSFKERFHASVRRLTPSC 433
S R+A++ +A L ++NR+R+++ +R TVGVDGS+YK HP + RFH ++RRL P
Sbjct: 379 SFRSANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKTHPQYSRRFHKTLRRLVPDS 438
Query: 434 EITFIESEEGSGRGAALVSAVACKKA 459
++ F+ SE GSG+GAA+V+AVA + A
Sbjct: 439 DVRFLLSESGSGKGAAMVTAVAYRLA 464
>gi|15991829 hexokinase 1 isoform HKI-ta/tb [Homo sapiens]
Length = 921
Score = 506 bits (1304), Expect = e-143
Identities = 245/451 (54%), Positives = 336/451 (74%), Gaps = 2/451 (0%)
Query: 7 QLPQPNSQVEQILAEFQLQEEDLKKVMRRMQKEMDRGLRLETHEEASVKMLPTYVRSTPE 66
+L + + Q+E+ LA F L ++ L +V +RM+ EM+ GLR +TH A VKMLP++VR TP+
Sbjct: 466 RLAEQHRQIEETLAHFHLTKDMLLEVKKRMRAEMELGLRKQTHNNAVVKMLPSFVRRTPD 525
Query: 67 GSEVGDFLSLDLGGTNFRVMLVKVGEGEEGQWSVKTKHQMYSIPEDAMTGTAEMLFDYIS 126
G+E GDFL+LDLGGTNFRV+LVK+ G++ +V+ +++Y+IP + M GT E LFD+I
Sbjct: 526 GTENGDFLALDLGGTNFRVLLVKIRSGKKR--TVEMHNKIYAIPIEIMQGTGEELFDHIV 583
Query: 127 ECISDFLDKHQMKHKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGNNVVGLLRD 186
CISDFLD +K ++PLGFTFSFP + +D GIL+ WTKGFKA+ G++VV LLRD
Sbjct: 584 SCISDFLDYMGIKGPRMPLGFTFSFPCQQTSLDAGILITWTKGFKATDCVGHDVVTLLRD 643
Query: 187 AIKRRGDFEMDVVAMVNDTVATMISCYYEDHQCEVGMIVGTGCNACYMEEMQNVELVEGD 246
AIKRR +F++DVVA+VNDTV TM++C YE+ CEVG+IVGTG NACYMEEM+NVE+VEGD
Sbjct: 644 AIKRREEFDLDVVAVVNDTVGTMMTCAYEEPTCEVGLIVGTGSNACYMEEMKNVEMVEGD 703
Query: 247 EGRMCVNTEWGAFGDSGELDEFLLEYDRLVDESSANPGQQLYEKLIGGKYMGELVRLVLL 306
+G+MC+N EWGAFGD+G LD+ YDRLVDE S N G+Q YEK+I G Y+GE+VR +L+
Sbjct: 704 QGQMCINMEWGAFGDNGCLDDIRTHYDRLVDEYSLNAGKQRYEKMISGMYLGEIVRNILI 763
Query: 307 RLVDENLLFHGEASEQLRTRGAFETRFVSQVESDTGDRKQIYNILSTLGLRPSTTDCDIV 366
+ LF G+ SE L+TRG FET+F+SQ+ESD Q+ IL LGL + D +V
Sbjct: 764 DFTKKGFLFRGQISETLKTRGIFETKFLSQIESDRLALLQVRAILQQLGLNSTCDDSILV 823
Query: 367 RRACESVSTRAAHMCSAGLAGVINRMRESRSEDVMRITVGVDGSVYKLHPSFKERFHASV 426
+ C VS RAA +C AG+A V++++RE+R D + +TVGVDG++YKLHP F H +V
Sbjct: 824 KTVCGVVSRRAAQLCGAGMAAVVDKIRENRGLDRLNVTVGVDGTLYKLHPHFSRIMHQTV 883
Query: 427 RRLTPSCEITFIESEEGSGRGAALVSAVACK 457
+ L+P C ++F+ SE+GSG+GAAL++AV +
Sbjct: 884 KELSPKCNVSFLLSEDGSGKGAALITAVGVR 914
Score = 476 bits (1225), Expect = e-134
Identities = 223/447 (49%), Positives = 322/447 (72%), Gaps = 2/447 (0%)
Query: 13 SQVEQILAEFQLQEEDLKKVMRRMQKEMDRGLRLETHEEASVKMLPTYVRSTPEGSEVGD 72
S++++ L +L +E L +M R +KEM GL + + A+VKMLPT+VRS P+GSE GD
Sbjct: 24 SEIDKYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEKGD 83
Query: 73 FLSLDLGGTNFRVMLVKVGEGEEGQWSVKTKHQMYSIPEDAMTGTAEMLFDYISECISDF 132
F++LDLGG++FR++ V+V E +V + ++Y PE+ + G+ LFD+++EC+ DF
Sbjct: 84 FIALDLGGSSFRILRVQVNH--EKNQNVHMESEVYDTPENIVHGSGSQLFDHVAECLGDF 141
Query: 133 LDKHQMKHKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGNNVVGLLRDAIKRRG 192
++K ++K KKLP+GFTFSFP + ID+ IL+ WTK FKASG EG +VV LL AIK+RG
Sbjct: 142 MEKRKIKDKKLPVGFTFSFPCQQSKIDEAILITWTKRFKASGVEGADVVKLLNKAIKKRG 201
Query: 193 DFEMDVVAMVNDTVATMISCYYEDHQCEVGMIVGTGCNACYMEEMQNVELVEGDEGRMCV 252
D++ ++VA+VNDTV TM++C Y+D CEVG+I+GTG NACYMEE+++++LVEGDEGRMC+
Sbjct: 202 DYDANIVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYMEELRHIDLVEGDEGRMCI 261
Query: 253 NTEWGAFGDSGELDEFLLEYDRLVDESSANPGQQLYEKLIGGKYMGELVRLVLLRLVDEN 312
NTEWGAFGD G L++ E+DR +D S NPG+QL+EK++ G Y+GELVRL+L+++ E
Sbjct: 262 NTEWGAFGDDGSLEDIRTEFDREIDRGSLNPGKQLFEKMVSGMYLGELVRLILVKMAKEG 321
Query: 313 LLFHGEASEQLRTRGAFETRFVSQVESDTGDRKQIYNILSTLGLRPSTTDCDIVRRACES 372
LLF G + +L TRG F T VS +E + IL+ LG+ PS DC V+ C
Sbjct: 322 LLFEGRITPELLTRGKFNTSDVSAIEKNKEGLHNAKEILTRLGVEPSDDDCVSVQHVCTI 381
Query: 373 VSTRAAHMCSAGLAGVINRMRESRSEDVMRITVGVDGSVYKLHPSFKERFHASVRRLTPS 432
VS R+A++ +A L ++NR+R+++ +R TVGVDGS+YK HP + RFH ++RRL P
Sbjct: 382 VSFRSANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKTHPQYSRRFHKTLRRLVPD 441
Query: 433 CEITFIESEEGSGRGAALVSAVACKKA 459
++ F+ SE GSG+GAA+V+AVA + A
Sbjct: 442 SDVRFLLSESGSGKGAAMVTAVAYRLA 468
>gi|15991831 hexokinase 1 isoform HKI-ta/tb [Homo sapiens]
Length = 921
Score = 506 bits (1304), Expect = e-143
Identities = 245/451 (54%), Positives = 336/451 (74%), Gaps = 2/451 (0%)
Query: 7 QLPQPNSQVEQILAEFQLQEEDLKKVMRRMQKEMDRGLRLETHEEASVKMLPTYVRSTPE 66
+L + + Q+E+ LA F L ++ L +V +RM+ EM+ GLR +TH A VKMLP++VR TP+
Sbjct: 466 RLAEQHRQIEETLAHFHLTKDMLLEVKKRMRAEMELGLRKQTHNNAVVKMLPSFVRRTPD 525
Query: 67 GSEVGDFLSLDLGGTNFRVMLVKVGEGEEGQWSVKTKHQMYSIPEDAMTGTAEMLFDYIS 126
G+E GDFL+LDLGGTNFRV+LVK+ G++ +V+ +++Y+IP + M GT E LFD+I
Sbjct: 526 GTENGDFLALDLGGTNFRVLLVKIRSGKKR--TVEMHNKIYAIPIEIMQGTGEELFDHIV 583
Query: 127 ECISDFLDKHQMKHKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGNNVVGLLRD 186
CISDFLD +K ++PLGFTFSFP + +D GIL+ WTKGFKA+ G++VV LLRD
Sbjct: 584 SCISDFLDYMGIKGPRMPLGFTFSFPCQQTSLDAGILITWTKGFKATDCVGHDVVTLLRD 643
Query: 187 AIKRRGDFEMDVVAMVNDTVATMISCYYEDHQCEVGMIVGTGCNACYMEEMQNVELVEGD 246
AIKRR +F++DVVA+VNDTV TM++C YE+ CEVG+IVGTG NACYMEEM+NVE+VEGD
Sbjct: 644 AIKRREEFDLDVVAVVNDTVGTMMTCAYEEPTCEVGLIVGTGSNACYMEEMKNVEMVEGD 703
Query: 247 EGRMCVNTEWGAFGDSGELDEFLLEYDRLVDESSANPGQQLYEKLIGGKYMGELVRLVLL 306
+G+MC+N EWGAFGD+G LD+ YDRLVDE S N G+Q YEK+I G Y+GE+VR +L+
Sbjct: 704 QGQMCINMEWGAFGDNGCLDDIRTHYDRLVDEYSLNAGKQRYEKMISGMYLGEIVRNILI 763
Query: 307 RLVDENLLFHGEASEQLRTRGAFETRFVSQVESDTGDRKQIYNILSTLGLRPSTTDCDIV 366
+ LF G+ SE L+TRG FET+F+SQ+ESD Q+ IL LGL + D +V
Sbjct: 764 DFTKKGFLFRGQISETLKTRGIFETKFLSQIESDRLALLQVRAILQQLGLNSTCDDSILV 823
Query: 367 RRACESVSTRAAHMCSAGLAGVINRMRESRSEDVMRITVGVDGSVYKLHPSFKERFHASV 426
+ C VS RAA +C AG+A V++++RE+R D + +TVGVDG++YKLHP F H +V
Sbjct: 824 KTVCGVVSRRAAQLCGAGMAAVVDKIRENRGLDRLNVTVGVDGTLYKLHPHFSRIMHQTV 883
Query: 427 RRLTPSCEITFIESEEGSGRGAALVSAVACK 457
+ L+P C ++F+ SE+GSG+GAAL++AV +
Sbjct: 884 KELSPKCNVSFLLSEDGSGKGAALITAVGVR 914
Score = 476 bits (1225), Expect = e-134
Identities = 223/447 (49%), Positives = 322/447 (72%), Gaps = 2/447 (0%)
Query: 13 SQVEQILAEFQLQEEDLKKVMRRMQKEMDRGLRLETHEEASVKMLPTYVRSTPEGSEVGD 72
S++++ L +L +E L +M R +KEM GL + + A+VKMLPT+VRS P+GSE GD
Sbjct: 24 SEIDKYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEKGD 83
Query: 73 FLSLDLGGTNFRVMLVKVGEGEEGQWSVKTKHQMYSIPEDAMTGTAEMLFDYISECISDF 132
F++LDLGG++FR++ V+V E +V + ++Y PE+ + G+ LFD+++EC+ DF
Sbjct: 84 FIALDLGGSSFRILRVQVNH--EKNQNVHMESEVYDTPENIVHGSGSQLFDHVAECLGDF 141
Query: 133 LDKHQMKHKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGNNVVGLLRDAIKRRG 192
++K ++K KKLP+GFTFSFP + ID+ IL+ WTK FKASG EG +VV LL AIK+RG
Sbjct: 142 MEKRKIKDKKLPVGFTFSFPCQQSKIDEAILITWTKRFKASGVEGADVVKLLNKAIKKRG 201
Query: 193 DFEMDVVAMVNDTVATMISCYYEDHQCEVGMIVGTGCNACYMEEMQNVELVEGDEGRMCV 252
D++ ++VA+VNDTV TM++C Y+D CEVG+I+GTG NACYMEE+++++LVEGDEGRMC+
Sbjct: 202 DYDANIVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYMEELRHIDLVEGDEGRMCI 261
Query: 253 NTEWGAFGDSGELDEFLLEYDRLVDESSANPGQQLYEKLIGGKYMGELVRLVLLRLVDEN 312
NTEWGAFGD G L++ E+DR +D S NPG+QL+EK++ G Y+GELVRL+L+++ E
Sbjct: 262 NTEWGAFGDDGSLEDIRTEFDREIDRGSLNPGKQLFEKMVSGMYLGELVRLILVKMAKEG 321
Query: 313 LLFHGEASEQLRTRGAFETRFVSQVESDTGDRKQIYNILSTLGLRPSTTDCDIVRRACES 372
LLF G + +L TRG F T VS +E + IL+ LG+ PS DC V+ C
Sbjct: 322 LLFEGRITPELLTRGKFNTSDVSAIEKNKEGLHNAKEILTRLGVEPSDDDCVSVQHVCTI 381
Query: 373 VSTRAAHMCSAGLAGVINRMRESRSEDVMRITVGVDGSVYKLHPSFKERFHASVRRLTPS 432
VS R+A++ +A L ++NR+R+++ +R TVGVDGS+YK HP + RFH ++RRL P
Sbjct: 382 VSFRSANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKTHPQYSRRFHKTLRRLVPD 441
Query: 433 CEITFIESEEGSGRGAALVSAVACKKA 459
++ F+ SE GSG+GAA+V+AVA + A
Sbjct: 442 SDVRFLLSESGSGKGAAMVTAVAYRLA 468
>gi|15991827 hexokinase 1 isoform HKI-R [Homo sapiens]
Length = 916
Score = 506 bits (1304), Expect = e-143
Identities = 245/451 (54%), Positives = 336/451 (74%), Gaps = 2/451 (0%)
Query: 7 QLPQPNSQVEQILAEFQLQEEDLKKVMRRMQKEMDRGLRLETHEEASVKMLPTYVRSTPE 66
+L + + Q+E+ LA F L ++ L +V +RM+ EM+ GLR +TH A VKMLP++VR TP+
Sbjct: 461 RLAEQHRQIEETLAHFHLTKDMLLEVKKRMRAEMELGLRKQTHNNAVVKMLPSFVRRTPD 520
Query: 67 GSEVGDFLSLDLGGTNFRVMLVKVGEGEEGQWSVKTKHQMYSIPEDAMTGTAEMLFDYIS 126
G+E GDFL+LDLGGTNFRV+LVK+ G++ +V+ +++Y+IP + M GT E LFD+I
Sbjct: 521 GTENGDFLALDLGGTNFRVLLVKIRSGKKR--TVEMHNKIYAIPIEIMQGTGEELFDHIV 578
Query: 127 ECISDFLDKHQMKHKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGNNVVGLLRD 186
CISDFLD +K ++PLGFTFSFP + +D GIL+ WTKGFKA+ G++VV LLRD
Sbjct: 579 SCISDFLDYMGIKGPRMPLGFTFSFPCQQTSLDAGILITWTKGFKATDCVGHDVVTLLRD 638
Query: 187 AIKRRGDFEMDVVAMVNDTVATMISCYYEDHQCEVGMIVGTGCNACYMEEMQNVELVEGD 246
AIKRR +F++DVVA+VNDTV TM++C YE+ CEVG+IVGTG NACYMEEM+NVE+VEGD
Sbjct: 639 AIKRREEFDLDVVAVVNDTVGTMMTCAYEEPTCEVGLIVGTGSNACYMEEMKNVEMVEGD 698
Query: 247 EGRMCVNTEWGAFGDSGELDEFLLEYDRLVDESSANPGQQLYEKLIGGKYMGELVRLVLL 306
+G+MC+N EWGAFGD+G LD+ YDRLVDE S N G+Q YEK+I G Y+GE+VR +L+
Sbjct: 699 QGQMCINMEWGAFGDNGCLDDIRTHYDRLVDEYSLNAGKQRYEKMISGMYLGEIVRNILI 758
Query: 307 RLVDENLLFHGEASEQLRTRGAFETRFVSQVESDTGDRKQIYNILSTLGLRPSTTDCDIV 366
+ LF G+ SE L+TRG FET+F+SQ+ESD Q+ IL LGL + D +V
Sbjct: 759 DFTKKGFLFRGQISETLKTRGIFETKFLSQIESDRLALLQVRAILQQLGLNSTCDDSILV 818
Query: 367 RRACESVSTRAAHMCSAGLAGVINRMRESRSEDVMRITVGVDGSVYKLHPSFKERFHASV 426
+ C VS RAA +C AG+A V++++RE+R D + +TVGVDG++YKLHP F H +V
Sbjct: 819 KTVCGVVSRRAAQLCGAGMAAVVDKIRENRGLDRLNVTVGVDGTLYKLHPHFSRIMHQTV 878
Query: 427 RRLTPSCEITFIESEEGSGRGAALVSAVACK 457
+ L+P C ++F+ SE+GSG+GAAL++AV +
Sbjct: 879 KELSPKCNVSFLLSEDGSGKGAALITAVGVR 909
Score = 474 bits (1219), Expect = e-134
Identities = 222/445 (49%), Positives = 320/445 (71%), Gaps = 2/445 (0%)
Query: 15 VEQILAEFQLQEEDLKKVMRRMQKEMDRGLRLETHEEASVKMLPTYVRSTPEGSEVGDFL 74
+++ L +L +E L +M R +KEM GL + + A+VKMLPT+VRS P+GSE GDF+
Sbjct: 21 IDKYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEKGDFI 80
Query: 75 SLDLGGTNFRVMLVKVGEGEEGQWSVKTKHQMYSIPEDAMTGTAEMLFDYISECISDFLD 134
+LDLGG++FR++ V+V E +V + ++Y PE+ + G+ LFD+++EC+ DF++
Sbjct: 81 ALDLGGSSFRILRVQVNH--EKNQNVHMESEVYDTPENIVHGSGSQLFDHVAECLGDFME 138
Query: 135 KHQMKHKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGNNVVGLLRDAIKRRGDF 194
K ++K KKLP+GFTFSFP + ID+ IL+ WTK FKASG EG +VV LL AIK+RGD+
Sbjct: 139 KRKIKDKKLPVGFTFSFPCQQSKIDEAILITWTKRFKASGVEGADVVKLLNKAIKKRGDY 198
Query: 195 EMDVVAMVNDTVATMISCYYEDHQCEVGMIVGTGCNACYMEEMQNVELVEGDEGRMCVNT 254
+ ++VA+VNDTV TM++C Y+D CEVG+I+GTG NACYMEE+++++LVEGDEGRMC+NT
Sbjct: 199 DANIVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYMEELRHIDLVEGDEGRMCINT 258
Query: 255 EWGAFGDSGELDEFLLEYDRLVDESSANPGQQLYEKLIGGKYMGELVRLVLLRLVDENLL 314
EWGAFGD G L++ E+DR +D S NPG+QL+EK++ G Y+GELVRL+L+++ E LL
Sbjct: 259 EWGAFGDDGSLEDIRTEFDREIDRGSLNPGKQLFEKMVSGMYLGELVRLILVKMAKEGLL 318
Query: 315 FHGEASEQLRTRGAFETRFVSQVESDTGDRKQIYNILSTLGLRPSTTDCDIVRRACESVS 374
F G + +L TRG F T VS +E + IL+ LG+ PS DC V+ C VS
Sbjct: 319 FEGRITPELLTRGKFNTSDVSAIEKNKEGLHNAKEILTRLGVEPSDDDCVSVQHVCTIVS 378
Query: 375 TRAAHMCSAGLAGVINRMRESRSEDVMRITVGVDGSVYKLHPSFKERFHASVRRLTPSCE 434
R+A++ +A L ++NR+R+++ +R TVGVDGS+YK HP + RFH ++RRL P +
Sbjct: 379 FRSANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKTHPQYSRRFHKTLRRLVPDSD 438
Query: 435 ITFIESEEGSGRGAALVSAVACKKA 459
+ F+ SE GSG+GAA+V+AVA + A
Sbjct: 439 VRFLLSESGSGKGAAMVTAVAYRLA 463
>gi|156151420 hexokinase domain containing 1 [Homo sapiens]
Length = 917
Score = 494 bits (1273), Expect = e-140
Identities = 237/450 (52%), Positives = 326/450 (72%), Gaps = 3/450 (0%)
Query: 6 SQLPQPNSQVEQILAEFQLQEEDLKKVMRRMQKEMDRGLRLETHEEASVKMLPTYVRSTP 65
S++ Q++++LA FQL E L V +M+ E++ GL+ ++H A+V+MLPTYV P
Sbjct: 461 SRVQAQRKQIDRVLALFQLTREQLVDVQAKMRAELEYGLKKKSHGLATVRMLPTYVCGLP 520
Query: 66 EGSEVGDFLSLDLGGTNFRVMLVKVGEGEEGQWSVKTKHQMYSIPEDAMTGTAEMLFDYI 125
+G+E G FL+LDLGGTNFRV+LVK+ G SV+ +++++IP + M GT E LFD+I
Sbjct: 521 DGTEKGKFLALDLGGTNFRVLLVKIRSGRR---SVRMYNKIFAIPLEIMQGTGEELFDHI 577
Query: 126 SECISDFLDKHQMKHKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGNNVVGLLR 185
+CI+DFLD +K LPLGFTFSFP R IDKG L+ WTKGFKA+ EG +VV +LR
Sbjct: 578 VQCIADFLDYMGLKGASLPLGFTFSFPCRQMSIDKGTLIGWTKGFKATDCEGEDVVDMLR 637
Query: 186 DAIKRRGDFEMDVVAMVNDTVATMISCYYEDHQCEVGMIVGTGCNACYMEEMQNVELVEG 245
+AIKRR +F++D+VA+VNDTV TM++C YED CE+G+I GTG N CYME+M+N+E+VEG
Sbjct: 638 EAIKRRNEFDLDIVAVVNDTVGTMMTCGYEDPNCEIGLIAGTGSNMCYMEDMRNIEMVEG 697
Query: 246 DEGRMCVNTEWGAFGDSGELDEFLLEYDRLVDESSANPGQQLYEKLIGGKYMGELVRLVL 305
EG+MC+NTEWG FGD+G +D+ YD VDE S NPG+Q YEK+ G Y+GE+VR +L
Sbjct: 698 GEGKMCINTEWGGFGDNGCIDDIRTRYDTEVDEGSLNPGKQRYEKMTSGMYLGEIVRQIL 757
Query: 306 LRLVDENLLFHGEASEQLRTRGAFETRFVSQVESDTGDRKQIYNILSTLGLRPSTTDCDI 365
+ L + LLF G+ SE+LRTRG FET+F+SQ+ESD Q+ IL LGL + D +
Sbjct: 758 IDLTKQGLLFRGQISERLRTRGIFETKFLSQIESDRLALLQVRRILQQLGLDSTCEDSIV 817
Query: 366 VRRACESVSTRAAHMCSAGLAGVINRMRESRSEDVMRITVGVDGSVYKLHPSFKERFHAS 425
V+ C +VS RAA +C AGLA ++ + RE + + +RITVGVDG++YKLHP F +
Sbjct: 818 VKEVCGAVSRRAAQLCGAGLAAIVEKRREDQGLEHLRITVGVDGTLYKLHPHFSRILQET 877
Query: 426 VRRLTPSCEITFIESEEGSGRGAALVSAVA 455
V+ L P C++TF+ SE+GSG+GAAL++AVA
Sbjct: 878 VKELAPRCDVTFMLSEDGSGKGAALITAVA 907
Score = 469 bits (1208), Expect = e-132
Identities = 221/444 (49%), Positives = 317/444 (71%), Gaps = 2/444 (0%)
Query: 14 QVEQILAEFQLQEEDLKKVMRRMQKEMDRGLRLETHEEASVKMLPTYVRSTPEGSEVGDF 73
+V++ L +L ++ L +MRR + EM++GL +T+ A+VKMLPT+VR+ P+GSE G+F
Sbjct: 21 KVDRFLYHMRLSDDTLLDIMRRFRAEMEKGLAKDTNPTAAVKMLPTFVRAIPDGSENGEF 80
Query: 74 LSLDLGGTNFRVMLVKVGEGEEGQWSVKTKHQMYSIPEDAMTGTAEMLFDYISECISDFL 133
LSLDLGG+ FRV+ V+V E EG+ V+ + Q Y P + + G LF+Y+++C++DF+
Sbjct: 81 LSLDLGGSKFRVLKVQVAE--EGKRHVQMESQFYPTPNEIIRGNGTELFEYVADCLADFM 138
Query: 134 DKHQMKHKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGNNVVGLLRDAIKRRGD 193
+KHKKLPLG TFSFP R +++G+LL+WTK FKA G + +VV L A++R D
Sbjct: 139 KTKDLKHKKLPLGLTFSFPCRQTKLEEGVLLSWTKKFKARGVQDTDVVSRLTKAMRRHKD 198
Query: 194 FEMDVVAMVNDTVATMISCYYEDHQCEVGMIVGTGCNACYMEEMQNVELVEGDEGRMCVN 253
++D++A+VNDTV TM++C Y+D CEVG+I+GTG NACYME+M N++LVEGDEGRMC+N
Sbjct: 199 MDVDILALVNDTVGTMMTCAYDDPYCEVGVIIGTGTNACYMEDMSNIDLVEGDEGRMCIN 258
Query: 254 TEWGAFGDSGELDEFLLEYDRLVDESSANPGQQLYEKLIGGKYMGELVRLVLLRLVDENL 313
TEWGAFGD G L++ E+DR +D S NPG+QL+EK+I G Y+GELVRL+LL++ L
Sbjct: 259 TEWGAFGDDGALEDIRTEFDRELDLGSLNPGKQLFEKMISGLYLGELVRLILLKMAKAGL 318
Query: 314 LFHGEASEQLRTRGAFETRFVSQVESDTGDRKQIYNILSTLGLRPSTTDCDIVRRACESV 373
LF GE S L T+G ETR V+ +E IL LGL PS DC V+ C V
Sbjct: 319 LFGGEKSSALHTKGKIETRHVAAMEKYKEGLANTREILVDLGLEPSEADCIAVQHVCTIV 378
Query: 374 STRAAHMCSAGLAGVINRMRESRSEDVMRITVGVDGSVYKLHPSFKERFHASVRRLTPSC 433
S R+A++C+A LA ++ R+RE++ + +R TVG+DG++YK+HP + +R H VR+L PSC
Sbjct: 379 SFRSANLCAAALAAILTRLRENKKVERLRTTVGMDGTLYKIHPQYPKRLHKVVRKLVPSC 438
Query: 434 EITFIESEEGSGRGAALVSAVACK 457
++ F+ SE GS +GAA+V+AVA +
Sbjct: 439 DVRFLLSESGSTKGAAMVTAVASR 462
>gi|194097330 hexokinase 3 [Homo sapiens]
Length = 923
Score = 473 bits (1216), Expect = e-133
Identities = 235/445 (52%), Positives = 321/445 (72%), Gaps = 9/445 (2%)
Query: 15 VEQILAEFQLQEEDLKKVMRRMQKEMDRGLRLETHEEASVKMLPTYVRSTPEGSEVGDFL 74
+E+ LA F+L + L V +M+K M +GLR E +S++MLPT+VR+TP+GSE GDFL
Sbjct: 483 LEETLAPFRLNHDQLAAVQAQMRKAMAKGLR---GEASSLRMLPTFVRATPDGSERGDFL 539
Query: 75 SLDLGGTNFRVMLVKVGEGEEGQWSVKTKHQMYSIPEDAMTGTAEMLFDYISECISDFLD 134
+LDLGGTNFRV+LV+V G V+ ++YSIPE G+ + LFD+I +CI DF
Sbjct: 540 ALDLGGTNFRVLLVRVTTG------VQITSEIYSIPETVAQGSGQQLFDHIVDCIVDFQQ 593
Query: 135 KHQMKHKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGNNVVGLLRDAIKRRGDF 194
K + + LPLGFTFSFP R +D+GILLNWTKGFKAS EG +VV LLR+AI RR
Sbjct: 594 KQGLSGQSLPLGFTFSFPCRQLGLDQGILLNWTKGFKASDCEGQDVVSLLREAITRRQAV 653
Query: 195 EMDVVAMVNDTVATMISCYYEDHQCEVGMIVGTGCNACYMEEMQNVELVEGDEGRMCVNT 254
E++VVA+VNDTV TM+SC YED +CE+G+IVGTG NACYMEE++NV V GD GRMC+N
Sbjct: 654 ELNVVAIVNDTVGTMMSCGYEDPRCEIGLIVGTGTNACYMEELRNVAGVPGDSGRMCINM 713
Query: 255 EWGAFGDSGELDEFLLEYDRLVDESSANPGQQLYEKLIGGKYMGELVRLVLLRLVDENLL 314
EWGAFGD G L +D VD++S NPG+Q +EK+I G Y+GE+VR +LL L +L
Sbjct: 714 EWGAFGDDGSLAMLSTRFDASVDQASINPGKQRFEKMISGMYLGEIVRHILLHLTSLGVL 773
Query: 315 FHGEASEQLRTRGAFETRFVSQVESDTGDRKQIYNILSTLGLRPSTTDCDIVRRACESVS 374
F G+ ++L+TR F+T+F+S++ESD+ +Q+ IL LGL ++ D +V C++VS
Sbjct: 774 FRGQQIQRLQTRDIFKTKFLSEIESDSLALRQVRAILEDLGLPLTSDDALMVLEVCQAVS 833
Query: 375 TRAAHMCSAGLAGVINRMRESRSEDVMRITVGVDGSVYKLHPSFKERFHASVRRLTPSCE 434
RAA +C AG+A V+ ++RE+R + + ++VGVDG++YKLHP F A+VR L P C
Sbjct: 834 QRAAQLCGAGVAAVVEKIRENRGLEELAVSVGVDGTLYKLHPRFSSLVAATVRELAPRCV 893
Query: 435 ITFIESEEGSGRGAALVSAVACKKA 459
+TF++SE+GSG+GAALV+AVAC+ A
Sbjct: 894 VTFLQSEDGSGKGAALVTAVACRLA 918
Score = 374 bits (961), Expect = e-104
Identities = 191/457 (41%), Positives = 287/457 (62%), Gaps = 7/457 (1%)
Query: 8 LPQPNSQ---VEQILAEFQLQEEDLKKVMRRMQKEMDRGLRLETHEEASVKMLPTYVRST 64
LP P+ V++ L +F++ L+++ + M++ LR + +V+MLPTYV ST
Sbjct: 23 LPGPSDSSELVQECLQQFKVTRAQLQQIQASLLGSMEQALRGQASPAPAVRMLPTYVGST 82
Query: 65 PEGSEVGDFLSLDLG--GTNFRVMLVKVGEGEEGQWSVKTKHQMYSIPEDAMTGTAEMLF 122
P G+E GDF+ L+LG G + RV+ V + G EG V+ + Q + IP++ M G + LF
Sbjct: 83 PHGTEQGDFVVLELGATGASLRVLWVTL-TGIEGH-RVEPRSQEFVIPQEVMLGAGQQLF 140
Query: 123 DYISECISDFLDKHQMKHKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGNNVVG 182
D+ + C+S+FLD + + L LGF+FSFP +D+ L++WTKGF+ SG EG +VV
Sbjct: 141 DFAAHCLSEFLDAQPVNKQGLQLGFSFSFPCHQTGLDRSTLISWTKGFRCSGVEGQDVVQ 200
Query: 183 LLRDAIKRRGDFEMDVVAMVNDTVATMISCYYEDHQCEVGMIVGTGCNACYMEEMQNVEL 242
LLRDAI+R+G + +DVVA+VNDTV TM+ C CEVG++V TG NACYMEE ++V +
Sbjct: 201 LLRDAIRRQGAYNIDVVAVVNDTVGTMMGCEPGVRPCEVGLVVDTGTNACYMEEARHVAV 260
Query: 243 VEGDEGRMCVNTEWGAFGDSGELDEFLLEYDRLVDESSANPGQQLYEKLIGGKYMGELVR 302
++ D GR+CV+ EWG+F D G L L +D +D S NPG Q +EK+IGG Y+GELVR
Sbjct: 261 LDEDRGRVCVSVEWGSFSDDGALGPVLTTFDHTLDHESLNPGAQRFEKMIGGLYLGELVR 320
Query: 303 LVLLRLVDENLLFHGEASEQLRTRGAFETRFVSQVESDTGDRKQIYNILSTLGLRPSTTD 362
LVL L +LF G S L ++G+ V+++E + +++ IL LGL P +D
Sbjct: 321 LVLAHLARCGVLFGGCTSPALLSQGSILLEHVAEMEDPSTGAARVHAILQDLGLSPGASD 380
Query: 363 CDIVRRACESVSTRAAHMCSAGLAGVINRMRESRSEDVMRITVGVDGSVYKLHPSFKERF 422
++V+ C +V TRAA +C+A LA V++ ++ SR + +++ V G V + HP F
Sbjct: 381 VELVQHVCAAVCTRAAQLCAAALAAVLSCLQHSREQQTLQVAVATGGRVCERHPRFCSVL 440
Query: 423 HASVRRLTPSCEITFIESEEGSGRGAALVSAVACKKA 459
+V L P C+++ I S +G GRG A+V+AVA + A
Sbjct: 441 QGTVMLLAPECDVSLIPSVDGGGRGVAMVTAVAARLA 477
>gi|22027525 Rac/Cdc42 guanine nucleotide exchange factor 6 [Homo
sapiens]
Length = 776
Score = 33.9 bits (76), Expect = 0.32
Identities = 16/48 (33%), Positives = 29/48 (60%)
Query: 7 QLPQPNSQVEQILAEFQLQEEDLKKVMRRMQKEMDRGLRLETHEEASV 54
+L Q N +++Q L E DL+K++RR+ K+ D +R E+ + S+
Sbjct: 727 ELKQENKRMKQCLEEELKSRRDLEKLVRRLLKQTDECIRGESSSKTSI 774
>gi|241982780 programmed cell death 6 interacting protein isoform 2
[Homo sapiens]
Length = 873
Score = 30.0 bits (66), Expect = 4.6
Identities = 28/94 (29%), Positives = 48/94 (51%), Gaps = 4/94 (4%)
Query: 4 PRSQLPQPNSQVEQ--ILAEFQLQEEDLKKVMRRMQKEMDRGLRLETHEEASVKMLPTYV 61
P+S L + S +EQ I QL +E L ++++R ++ +D LRL EEA+ L
Sbjct: 419 PQSILTKSRSVIEQGGIQTVDQLIKE-LPELLQRNREILDESLRLLDEEEATDNDLRAKF 477
Query: 62 RSTPEGSEVGD-FLSLDLGGTNFRVMLVKVGEGE 94
+ + + + + L GTNFR +L K + +
Sbjct: 478 KERWQRTPSNELYKPLRAEGTNFRTVLDKAVQAD 511
>gi|22027538 programmed cell death 6 interacting protein isoform 1
[Homo sapiens]
Length = 868
Score = 30.0 bits (66), Expect = 4.6
Identities = 28/94 (29%), Positives = 48/94 (51%), Gaps = 4/94 (4%)
Query: 4 PRSQLPQPNSQVEQ--ILAEFQLQEEDLKKVMRRMQKEMDRGLRLETHEEASVKMLPTYV 61
P+S L + S +EQ I QL +E L ++++R ++ +D LRL EEA+ L
Sbjct: 414 PQSILTKSRSVIEQGGIQTVDQLIKE-LPELLQRNREILDESLRLLDEEEATDNDLRAKF 472
Query: 62 RSTPEGSEVGD-FLSLDLGGTNFRVMLVKVGEGE 94
+ + + + + L GTNFR +L K + +
Sbjct: 473 KERWQRTPSNELYKPLRAEGTNFRTVLDKAVQAD 506
>gi|153791497 ciliary rootlet coiled-coil [Homo sapiens]
Length = 2017
Score = 30.0 bits (66), Expect = 4.6
Identities = 16/48 (33%), Positives = 29/48 (60%), Gaps = 1/48 (2%)
Query: 5 RSQLP-QPNSQVEQILAEFQLQEEDLKKVMRRMQKEMDRGLRLETHEE 51
R+QL Q + E++LA + ++E+L + + +Q+E D GL L E+
Sbjct: 1013 RAQLQSQLQREQEELLARLEAEKEELSEEIAALQQERDEGLLLAESEK 1060
>gi|81295816 nasopharyngeal epithelium specific protein 1 [Homo
sapiens]
Length = 551
Score = 30.0 bits (66), Expect = 4.6
Identities = 16/38 (42%), Positives = 25/38 (65%), Gaps = 2/38 (5%)
Query: 5 RSQLPQPNSQVEQILAEF--QLQEEDLKKVMRRMQKEM 40
RS L + Q ++ + E+ QLQEEDLK + RR Q+++
Sbjct: 272 RSLLAEQREQEKEQMLEYMEQLQEEDLKDMERRQQQKL 309
>gi|53832011 calcium channel, voltage-dependent, T type, alpha 1H
subunit isoform b [Homo sapiens]
Length = 2347
Score = 29.6 bits (65), Expect = 6.1
Identities = 17/36 (47%), Positives = 20/36 (55%), Gaps = 4/36 (11%)
Query: 416 PSFKERFHASVRRLTPSCEIT----FIESEEGSGRG 447
PS E ++RR TPSCE T +E EGSG G
Sbjct: 2200 PSAAEGGSTTLRRRTPSCEATPHRDSLEPTEGSGAG 2235
>gi|53832009 calcium channel, voltage-dependent, T type, alpha 1H
subunit isoform a [Homo sapiens]
Length = 2353
Score = 29.6 bits (65), Expect = 6.1
Identities = 17/36 (47%), Positives = 20/36 (55%), Gaps = 4/36 (11%)
Query: 416 PSFKERFHASVRRLTPSCEIT----FIESEEGSGRG 447
PS E ++RR TPSCE T +E EGSG G
Sbjct: 2206 PSAAEGGSTTLRRRTPSCEATPHRDSLEPTEGSGAG 2241
>gi|4502443 dystonin isoform 1e precursor [Homo sapiens]
Length = 2649
Score = 29.6 bits (65), Expect = 6.1
Identities = 16/61 (26%), Positives = 32/61 (52%)
Query: 10 QPNSQVEQILAEFQLQEEDLKKVMRRMQKEMDRGLRLETHEEASVKMLPTYVRSTPEGSE 69
Q S +++I +QL+ E L ++Q+E+DR R E +++ L + + S + E
Sbjct: 1457 QEASDLKKIKRNYQLELESLNHEKGKLQREVDRITRAHAVAEKNIQHLNSQIHSFRDEKE 1516
Query: 70 V 70
+
Sbjct: 1517 L 1517
>gi|160948610 E3 ubiquitin-protein ligase UBR3 [Homo sapiens]
Length = 1888
Score = 29.6 bits (65), Expect = 6.1
Identities = 18/93 (19%), Positives = 42/93 (45%), Gaps = 23/93 (24%)
Query: 176 EGNNVVGLLRDAIKRRG--------DFEMDVVAMVNDTVATMISCYYEDHQCEVGMIVG- 226
+ ++V+G RD ++ + + D A V+D +++ Y++D C + + +G
Sbjct: 1258 QASSVLGQCRDNVEPKKLPISEEEQIYPWDTCAAVHDVRLSLLQRYFKDSSCLLAVSIGW 1317
Query: 227 --------------TGCNACYMEEMQNVELVEG 245
C+ YME ++N ++++G
Sbjct: 1318 EGGVYVQTCGHTLHIDCHKSYMESLRNDQVLQG 1350
>gi|63055059 SH3 and PX domains 2B [Homo sapiens]
Length = 911
Score = 29.3 bits (64), Expect = 7.9
Identities = 28/112 (25%), Positives = 47/112 (41%), Gaps = 12/112 (10%)
Query: 7 QLPQPNSQVEQILAEFQLQEEDLKKVMRRMQKEMDRGLRLETHEEASV--KMLPTYVRST 64
QLP SQ +++L F+ + EDL KE G + ++ SV +L YV
Sbjct: 107 QLPPYISQCDEVLQFFETRPEDLNP-----PKEEHIGKKKSGGDQTSVDPMVLEQYVVVA 161
Query: 65 PEGSEVGDFLSLDLGGTNFRVMLVKVGEGEEGQWSVKTKHQMYSIPEDAMTG 116
+ +SL +G ++ + + E G W V T + +P + G
Sbjct: 162 NYQKQESSEISLSVG-----QVVDIIEKNESGWWFVSTAEEQGWVPATCLEG 208
>gi|117414143 hypothetical protein LOC55603 [Homo sapiens]
Length = 442
Score = 29.3 bits (64), Expect = 7.9
Identities = 23/101 (22%), Positives = 44/101 (43%), Gaps = 10/101 (9%)
Query: 116 GTAEMLFDYISECISDFLDKHQMKHKKLPLGFTFSFPVRH----EDIDKGILLNWTKGFK 171
G + + D + +C+ DFL + K K PL ++ + D D+ L++
Sbjct: 152 GEFQTVKDVVLDCLLDFLPEGVNKEKITPLTLKEAYVQKMVKVCNDSDRWSLIS------ 205
Query: 172 ASGAEGNNVVGLLRDAIKRRGDFEMDVVAMVNDTVATMISC 212
S G NV D+++R+ +F +D + D++ C
Sbjct: 206 LSNNSGKNVELKFVDSLRRQFEFSVDSFQIKLDSLLLFYEC 246
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.135 0.393
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,126,693
Number of Sequences: 37866
Number of extensions: 744893
Number of successful extensions: 2082
Number of sequences better than 10.0: 22
Number of HSP's better than 10.0 without gapping: 14
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 2037
Number of HSP's gapped (non-prelim): 36
length of query: 464
length of database: 18,247,518
effective HSP length: 106
effective length of query: 358
effective length of database: 14,233,722
effective search space: 5095672476
effective search space used: 5095672476
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.