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Search of human proteins with 157388921
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|157388921 transmembrane and coiled-coil domains 3 [Homo
sapiens]
(677 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|157388921 transmembrane and coiled-coil domains 3 [Homo sapiens] 1301 0.0
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 44 5e-04
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 44 5e-04
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 44 5e-04
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 44 5e-04
gi|224586773 hypothetical protein LOC643854 [Homo sapiens] 42 0.001
gi|92859701 myosin VI [Homo sapiens] 42 0.001
gi|21735548 centrosomal protein 2 [Homo sapiens] 42 0.002
gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens] 42 0.002
gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens] 42 0.002
gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens] 42 0.002
gi|51972208 leucine, glutamate and lysine rich 1 [Homo sapiens] 42 0.002
gi|146262005 CTAGE family, member 6 [Homo sapiens] 42 0.002
gi|110815815 centlein isoform 1 [Homo sapiens] 42 0.002
gi|70166430 GRINL1A combined protein isoform 2 [Homo sapiens] 41 0.003
gi|70166414 GRINL1A combined protein isoform 1 [Homo sapiens] 41 0.003
gi|111494235 GRINL1A combined protein isoform 8 [Homo sapiens] 41 0.003
gi|70166580 GRINL1A upstream protein isoform 7 [Homo sapiens] 41 0.003
gi|56847634 hypothetical protein LOC441294 [Homo sapiens] 41 0.003
gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo ... 41 0.004
gi|221219020 NYD-SP11 protein [Homo sapiens] 40 0.005
gi|239735588 TRAF2 and NCK interacting kinase isoform 6 [Homo sa... 40 0.005
gi|239735586 TRAF2 and NCK interacting kinase isoform 5 [Homo sa... 40 0.005
gi|239735580 TRAF2 and NCK interacting kinase isoform 2 [Homo sa... 40 0.005
gi|55741807 TRAF2 and NCK interacting kinase isoform 1 [Homo sap... 40 0.005
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo... 40 0.005
gi|193290160 CTAGE family, member 4 [Homo sapiens] 40 0.007
gi|27734883 tripartite motif family-like 2 [Homo sapiens] 40 0.007
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 40 0.007
gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta ... 40 0.007
>gi|157388921 transmembrane and coiled-coil domains 3 [Homo sapiens]
Length = 677
Score = 1301 bits (3368), Expect = 0.0
Identities = 677/677 (100%), Positives = 677/677 (100%)
Query: 1 MKVLGRSFFWVLFPVLPWAVQAVEHEEVAQRVIKLHRGRGVAAMQSRQWVRDSCRKLSGL 60
MKVLGRSFFWVLFPVLPWAVQAVEHEEVAQRVIKLHRGRGVAAMQSRQWVRDSCRKLSGL
Sbjct: 1 MKVLGRSFFWVLFPVLPWAVQAVEHEEVAQRVIKLHRGRGVAAMQSRQWVRDSCRKLSGL 60
Query: 61 LRQKNAVLNKLKTAIGAVEKDVGLSDEEKLFQVHTFEIFQKELNESENSVFQAVYGLQRA 120
LRQKNAVLNKLKTAIGAVEKDVGLSDEEKLFQVHTFEIFQKELNESENSVFQAVYGLQRA
Sbjct: 61 LRQKNAVLNKLKTAIGAVEKDVGLSDEEKLFQVHTFEIFQKELNESENSVFQAVYGLQRA 120
Query: 121 LQGDYKDVVNMKESSRQRLEALREAAIKEETEYMELLAAEKHQVEALKNMQHQNQSLSML 180
LQGDYKDVVNMKESSRQRLEALREAAIKEETEYMELLAAEKHQVEALKNMQHQNQSLSML
Sbjct: 121 LQGDYKDVVNMKESSRQRLEALREAAIKEETEYMELLAAEKHQVEALKNMQHQNQSLSML 180
Query: 181 DEILEDVRKAADRLEEEIEEHAFDDNKSVKGVNFEAVLRVEEEEANSKQNITKREVEDDL 240
DEILEDVRKAADRLEEEIEEHAFDDNKSVKGVNFEAVLRVEEEEANSKQNITKREVEDDL
Sbjct: 181 DEILEDVRKAADRLEEEIEEHAFDDNKSVKGVNFEAVLRVEEEEANSKQNITKREVEDDL 240
Query: 241 GLSMLIDSQNNQYILTKPRDSTIPRADHHFIKDIVTIGMLSLPCGWLCTAIGLPTMFGYI 300
GLSMLIDSQNNQYILTKPRDSTIPRADHHFIKDIVTIGMLSLPCGWLCTAIGLPTMFGYI
Sbjct: 241 GLSMLIDSQNNQYILTKPRDSTIPRADHHFIKDIVTIGMLSLPCGWLCTAIGLPTMFGYI 300
Query: 301 ICGVLLGPSGLNSIKSIVQVETLGEFGVFFTLFLVGLEFSPEKLRKVWKISLQGPCYMTL 360
ICGVLLGPSGLNSIKSIVQVETLGEFGVFFTLFLVGLEFSPEKLRKVWKISLQGPCYMTL
Sbjct: 301 ICGVLLGPSGLNSIKSIVQVETLGEFGVFFTLFLVGLEFSPEKLRKVWKISLQGPCYMTL 360
Query: 361 LMIAFGLLWGHLLRIKPTQSVFISTCLSLSSTPLVSRFLMGSARGDKEGDIDYSTVLLGM 420
LMIAFGLLWGHLLRIKPTQSVFISTCLSLSSTPLVSRFLMGSARGDKEGDIDYSTVLLGM
Sbjct: 361 LMIAFGLLWGHLLRIKPTQSVFISTCLSLSSTPLVSRFLMGSARGDKEGDIDYSTVLLGM 420
Query: 421 LVTQDVQLGLFMAVMPTLIQAGASASSSIVVEVLRILVLIGQILFSLAAVFLLCLVIKKY 480
LVTQDVQLGLFMAVMPTLIQAGASASSSIVVEVLRILVLIGQILFSLAAVFLLCLVIKKY
Sbjct: 421 LVTQDVQLGLFMAVMPTLIQAGASASSSIVVEVLRILVLIGQILFSLAAVFLLCLVIKKY 480
Query: 481 LIGPYYRKLHMESKGNKEILILGISAFIFLMLTVTELLDVSMELGCFLAGALVSSQGPVV 540
LIGPYYRKLHMESKGNKEILILGISAFIFLMLTVTELLDVSMELGCFLAGALVSSQGPVV
Sbjct: 481 LIGPYYRKLHMESKGNKEILILGISAFIFLMLTVTELLDVSMELGCFLAGALVSSQGPVV 540
Query: 541 TEEIATSIEPIRDFLAIVFFASIGLHVFPTFVAYELTVLVFLTLSVVVMKFLLAALVLSL 600
TEEIATSIEPIRDFLAIVFFASIGLHVFPTFVAYELTVLVFLTLSVVVMKFLLAALVLSL
Sbjct: 541 TEEIATSIEPIRDFLAIVFFASIGLHVFPTFVAYELTVLVFLTLSVVVMKFLLAALVLSL 600
Query: 601 ILPRSSQYIKWIVSAGLAQVSEFSFVLGSRARRAGVISREVYLLILSVTTLSLLLAPVLW 660
ILPRSSQYIKWIVSAGLAQVSEFSFVLGSRARRAGVISREVYLLILSVTTLSLLLAPVLW
Sbjct: 601 ILPRSSQYIKWIVSAGLAQVSEFSFVLGSRARRAGVISREVYLLILSVTTLSLLLAPVLW 660
Query: 661 RAAITRCVPRPERRSSL 677
RAAITRCVPRPERRSSL
Sbjct: 661 RAAITRCVPRPERRSSL 677
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 43.9 bits (102), Expect = 5e-04
Identities = 51/235 (21%), Positives = 110/235 (46%), Gaps = 18/235 (7%)
Query: 21 QAVEHEEVAQRVIKLHRGRGVAAMQSRQWVRDSCRKLSGLLRQKNAVLNKLKTAIGAVEK 80
+A+E +E +R K+ + + S+ V + +L R + ++KT + +E
Sbjct: 1494 EALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELED 1553
Query: 81 DVGLSDEEKL-FQVHTFEI---FQKELNESENSVFQAVYGLQRALQGDYKDVVNMKESSR 136
++ +++ KL +V+ + F+++L + + LQR L +Y+ +++ +
Sbjct: 1554 ELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLH-EYE--TELEDERK 1610
Query: 137 QR-LEALREAAIKEETEYMELLA--AEKHQVEALKNMQHQNQSLSMLDEILEDVRKAADR 193
QR L A + ++ + + +EL A A K + EA+K ++ + LED R + D
Sbjct: 1611 QRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRD- 1669
Query: 194 LEEEIEEHAFDDNKSVKGVNFEAVLRVEE----EEANSKQNITKREVEDDLGLSM 244
EI A ++ K K + + + E+ E A + ++ K E+ ++L S+
Sbjct: 1670 ---EIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSL 1721
Score = 36.2 bits (82), Expect = 0.10
Identities = 42/186 (22%), Positives = 81/186 (43%), Gaps = 11/186 (5%)
Query: 21 QAVEHEEVAQRVIKLHRGRGVAAMQSRQ----WVRDSCRKLSGLLRQKNAVLNKLKTAIG 76
+ +E EE A++ ++L + A ++ + + D KLS + ++ L T +
Sbjct: 957 EQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLA 1016
Query: 77 AVEKDVGLSDEEKLFQVHTFEIFQKELN-ESENSVFQAVYGLQRALQGDYKDVVNMKESS 135
E++ + KL H I + E+ + E Q + L+R L+GD D
Sbjct: 1017 --EEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADL 1074
Query: 136 RQRLEALREAAIKEETEYMELLAAEKHQV----EALKNMQHQNQSLSMLDEILEDVRKAA 191
+ ++ L+ K+E E LA ++ ALK ++ +S L E L+ R A
Sbjct: 1075 QAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAAR 1134
Query: 192 DRLEEE 197
++ E++
Sbjct: 1135 NKAEKQ 1140
Score = 33.5 bits (75), Expect = 0.66
Identities = 44/206 (21%), Positives = 79/206 (38%), Gaps = 20/206 (9%)
Query: 21 QAVEHEEVAQRVIKLHRGRGVAAMQSRQWVRDSCRKLSGLLRQ-KNAVLNKLKTAIGAVE 79
+A + E + R +RQ + ++L L + + AV +K K+ I A+E
Sbjct: 1761 KATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALE 1820
Query: 80 KDVGLSDEEKLFQVHTFEIFQKELNESENSVFQAVYGLQ--RALQGDYKD--------VV 129
+ +E+ + + K L + + + + + ++ R + YK+ V
Sbjct: 1821 AKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVK 1880
Query: 130 NMK------ESSRQRLEALREAAIKEETEYMELLAAEKHQVEALKNMQHQNQSLSMLDEI 183
+K E QR+ A R +E E E A +V ALK+ + S +
Sbjct: 1881 QLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLRRGNETSFVPSR 1940
Query: 184 LEDVRKA---ADRLEEEIEEHAFDDN 206
R+ AD EEE + D N
Sbjct: 1941 RSGGRRVIENADGSEEETDTRDADFN 1966
Score = 30.8 bits (68), Expect = 4.3
Identities = 39/149 (26%), Positives = 64/149 (42%), Gaps = 23/149 (15%)
Query: 105 ESENSVFQAVYGLQRALQGDYKDVVNMKESSRQRLE--------ALREAA-IKEETEY-- 153
E + F + ++ + Y D + E+ + E AL EA KEE E
Sbjct: 1447 EKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTN 1506
Query: 154 ------MELLAAEKHQVEALKNMQHQNQSLSMLDEILEDVRKAADRLEEEIEEHAFDDNK 207
ME L + K V KN+ +S L+ +E+++ + LE+E++ A +D K
Sbjct: 1507 KMLKAEMEDLVSSKDDVG--KNVHELEKSKRALETQMEEMKTQLEELEDELQ--ATEDAK 1562
Query: 208 SVKGVNFEAVLRVEEE--EANSKQNITKR 234
VN +A+ E +A +QN KR
Sbjct: 1563 LRLEVNMQALKGQFERDLQARDEQNEEKR 1591
Score = 30.4 bits (67), Expect = 5.6
Identities = 51/239 (21%), Positives = 95/239 (39%), Gaps = 17/239 (7%)
Query: 9 FWVLFPVLPWAVQAVEHEEVAQRVIKLHRGRGVAAMQSRQWVRDSCRKLSGLLRQKNAVL 68
+W LF + +Q EE Q + ++ +++ +K S L +KN +
Sbjct: 834 WWRLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQ 893
Query: 69 NKLKTAIG----AVEKDVGLSDEEKLFQVHTFEIFQKELNESENSVFQAVYGLQRALQGD 124
+L+ A E V L+ +++ + E+ + L E E+ Q LQ +
Sbjct: 894 EQLQAETELYAEAEEMRVRLAAKKQELEEILHEM-EARLEEEEDRGQQ--------LQAE 944
Query: 125 YKDVVNMKESSRQRLEALREAAIKEETEYMELLAAEKHQVEALKNMQHQNQSLS----ML 180
K + ++LE A K + E + A K + + M QN LS +L
Sbjct: 945 RKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLL 1004
Query: 181 DEILEDVRKAADRLEEEIEEHAFDDNKSVKGVNFEAVLRVEEEEANSKQNITKREVEDD 239
+E + D+ EE+ + NK ++ V +EE++ + KR++E D
Sbjct: 1005 EERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGD 1063
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 43.9 bits (102), Expect = 5e-04
Identities = 51/235 (21%), Positives = 110/235 (46%), Gaps = 18/235 (7%)
Query: 21 QAVEHEEVAQRVIKLHRGRGVAAMQSRQWVRDSCRKLSGLLRQKNAVLNKLKTAIGAVEK 80
+A+E +E +R K+ + + S+ V + +L R + ++KT + +E
Sbjct: 1501 EALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELED 1560
Query: 81 DVGLSDEEKL-FQVHTFEI---FQKELNESENSVFQAVYGLQRALQGDYKDVVNMKESSR 136
++ +++ KL +V+ + F+++L + + LQR L +Y+ +++ +
Sbjct: 1561 ELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLH-EYE--TELEDERK 1617
Query: 137 QR-LEALREAAIKEETEYMELLA--AEKHQVEALKNMQHQNQSLSMLDEILEDVRKAADR 193
QR L A + ++ + + +EL A A K + EA+K ++ + LED R + D
Sbjct: 1618 QRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRD- 1676
Query: 194 LEEEIEEHAFDDNKSVKGVNFEAVLRVEE----EEANSKQNITKREVEDDLGLSM 244
EI A ++ K K + + + E+ E A + ++ K E+ ++L S+
Sbjct: 1677 ---EIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSL 1728
Score = 36.2 bits (82), Expect = 0.10
Identities = 42/186 (22%), Positives = 81/186 (43%), Gaps = 11/186 (5%)
Query: 21 QAVEHEEVAQRVIKLHRGRGVAAMQSRQ----WVRDSCRKLSGLLRQKNAVLNKLKTAIG 76
+ +E EE A++ ++L + A ++ + + D KLS + ++ L T +
Sbjct: 964 EQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLA 1023
Query: 77 AVEKDVGLSDEEKLFQVHTFEIFQKELN-ESENSVFQAVYGLQRALQGDYKDVVNMKESS 135
E++ + KL H I + E+ + E Q + L+R L+GD D
Sbjct: 1024 --EEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADL 1081
Query: 136 RQRLEALREAAIKEETEYMELLAAEKHQV----EALKNMQHQNQSLSMLDEILEDVRKAA 191
+ ++ L+ K+E E LA ++ ALK ++ +S L E L+ R A
Sbjct: 1082 QAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAAR 1141
Query: 192 DRLEEE 197
++ E++
Sbjct: 1142 NKAEKQ 1147
Score = 33.5 bits (75), Expect = 0.66
Identities = 44/206 (21%), Positives = 79/206 (38%), Gaps = 20/206 (9%)
Query: 21 QAVEHEEVAQRVIKLHRGRGVAAMQSRQWVRDSCRKLSGLLRQ-KNAVLNKLKTAIGAVE 79
+A + E + R +RQ + ++L L + + AV +K K+ I A+E
Sbjct: 1768 KATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALE 1827
Query: 80 KDVGLSDEEKLFQVHTFEIFQKELNESENSVFQAVYGLQ--RALQGDYKD--------VV 129
+ +E+ + + K L + + + + + ++ R + YK+ V
Sbjct: 1828 AKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVK 1887
Query: 130 NMK------ESSRQRLEALREAAIKEETEYMELLAAEKHQVEALKNMQHQNQSLSMLDEI 183
+K E QR+ A R +E E E A +V ALK+ + S +
Sbjct: 1888 QLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLRRGNETSFVPSR 1947
Query: 184 LEDVRKA---ADRLEEEIEEHAFDDN 206
R+ AD EEE + D N
Sbjct: 1948 RSGGRRVIENADGSEEETDTRDADFN 1973
Score = 30.8 bits (68), Expect = 4.3
Identities = 39/149 (26%), Positives = 64/149 (42%), Gaps = 23/149 (15%)
Query: 105 ESENSVFQAVYGLQRALQGDYKDVVNMKESSRQRLE--------ALREAA-IKEETEY-- 153
E + F + ++ + Y D + E+ + E AL EA KEE E
Sbjct: 1454 EKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTN 1513
Query: 154 ------MELLAAEKHQVEALKNMQHQNQSLSMLDEILEDVRKAADRLEEEIEEHAFDDNK 207
ME L + K V KN+ +S L+ +E+++ + LE+E++ A +D K
Sbjct: 1514 KMLKAEMEDLVSSKDDVG--KNVHELEKSKRALETQMEEMKTQLEELEDELQ--ATEDAK 1569
Query: 208 SVKGVNFEAVLRVEEE--EANSKQNITKR 234
VN +A+ E +A +QN KR
Sbjct: 1570 LRLEVNMQALKGQFERDLQARDEQNEEKR 1598
Score = 30.4 bits (67), Expect = 5.6
Identities = 51/239 (21%), Positives = 95/239 (39%), Gaps = 17/239 (7%)
Query: 9 FWVLFPVLPWAVQAVEHEEVAQRVIKLHRGRGVAAMQSRQWVRDSCRKLSGLLRQKNAVL 68
+W LF + +Q EE Q + ++ +++ +K S L +KN +
Sbjct: 841 WWRLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQ 900
Query: 69 NKLKTAIG----AVEKDVGLSDEEKLFQVHTFEIFQKELNESENSVFQAVYGLQRALQGD 124
+L+ A E V L+ +++ + E+ + L E E+ Q LQ +
Sbjct: 901 EQLQAETELYAEAEEMRVRLAAKKQELEEILHEM-EARLEEEEDRGQQ--------LQAE 951
Query: 125 YKDVVNMKESSRQRLEALREAAIKEETEYMELLAAEKHQVEALKNMQHQNQSLS----ML 180
K + ++LE A K + E + A K + + M QN LS +L
Sbjct: 952 RKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLL 1011
Query: 181 DEILEDVRKAADRLEEEIEEHAFDDNKSVKGVNFEAVLRVEEEEANSKQNITKREVEDD 239
+E + D+ EE+ + NK ++ V +EE++ + KR++E D
Sbjct: 1012 EERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGD 1070
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 43.9 bits (102), Expect = 5e-04
Identities = 51/235 (21%), Positives = 110/235 (46%), Gaps = 18/235 (7%)
Query: 21 QAVEHEEVAQRVIKLHRGRGVAAMQSRQWVRDSCRKLSGLLRQKNAVLNKLKTAIGAVEK 80
+A+E +E +R K+ + + S+ V + +L R + ++KT + +E
Sbjct: 1501 EALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELED 1560
Query: 81 DVGLSDEEKL-FQVHTFEI---FQKELNESENSVFQAVYGLQRALQGDYKDVVNMKESSR 136
++ +++ KL +V+ + F+++L + + LQR L +Y+ +++ +
Sbjct: 1561 ELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLH-EYE--TELEDERK 1617
Query: 137 QR-LEALREAAIKEETEYMELLA--AEKHQVEALKNMQHQNQSLSMLDEILEDVRKAADR 193
QR L A + ++ + + +EL A A K + EA+K ++ + LED R + D
Sbjct: 1618 QRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRD- 1676
Query: 194 LEEEIEEHAFDDNKSVKGVNFEAVLRVEE----EEANSKQNITKREVEDDLGLSM 244
EI A ++ K K + + + E+ E A + ++ K E+ ++L S+
Sbjct: 1677 ---EIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSL 1728
Score = 36.2 bits (82), Expect = 0.10
Identities = 42/186 (22%), Positives = 81/186 (43%), Gaps = 11/186 (5%)
Query: 21 QAVEHEEVAQRVIKLHRGRGVAAMQSRQ----WVRDSCRKLSGLLRQKNAVLNKLKTAIG 76
+ +E EE A++ ++L + A ++ + + D KLS + ++ L T +
Sbjct: 964 EQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLA 1023
Query: 77 AVEKDVGLSDEEKLFQVHTFEIFQKELN-ESENSVFQAVYGLQRALQGDYKDVVNMKESS 135
E++ + KL H I + E+ + E Q + L+R L+GD D
Sbjct: 1024 --EEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADL 1081
Query: 136 RQRLEALREAAIKEETEYMELLAAEKHQV----EALKNMQHQNQSLSMLDEILEDVRKAA 191
+ ++ L+ K+E E LA ++ ALK ++ +S L E L+ R A
Sbjct: 1082 QAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAAR 1141
Query: 192 DRLEEE 197
++ E++
Sbjct: 1142 NKAEKQ 1147
Score = 30.8 bits (68), Expect = 4.3
Identities = 39/149 (26%), Positives = 64/149 (42%), Gaps = 23/149 (15%)
Query: 105 ESENSVFQAVYGLQRALQGDYKDVVNMKESSRQRLE--------ALREAA-IKEETEY-- 153
E + F + ++ + Y D + E+ + E AL EA KEE E
Sbjct: 1454 EKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTN 1513
Query: 154 ------MELLAAEKHQVEALKNMQHQNQSLSMLDEILEDVRKAADRLEEEIEEHAFDDNK 207
ME L + K V KN+ +S L+ +E+++ + LE+E++ A +D K
Sbjct: 1514 KMLKAEMEDLVSSKDDVG--KNVHELEKSKRALETQMEEMKTQLEELEDELQ--ATEDAK 1569
Query: 208 SVKGVNFEAVLRVEEE--EANSKQNITKR 234
VN +A+ E +A +QN KR
Sbjct: 1570 LRLEVNMQALKGQFERDLQARDEQNEEKR 1598
Score = 30.4 bits (67), Expect = 5.6
Identities = 51/239 (21%), Positives = 95/239 (39%), Gaps = 17/239 (7%)
Query: 9 FWVLFPVLPWAVQAVEHEEVAQRVIKLHRGRGVAAMQSRQWVRDSCRKLSGLLRQKNAVL 68
+W LF + +Q EE Q + ++ +++ +K S L +KN +
Sbjct: 841 WWRLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQ 900
Query: 69 NKLKTAIG----AVEKDVGLSDEEKLFQVHTFEIFQKELNESENSVFQAVYGLQRALQGD 124
+L+ A E V L+ +++ + E+ + L E E+ Q LQ +
Sbjct: 901 EQLQAETELYAEAEEMRVRLAAKKQELEEILHEM-EARLEEEEDRGQQ--------LQAE 951
Query: 125 YKDVVNMKESSRQRLEALREAAIKEETEYMELLAAEKHQVEALKNMQHQNQSLS----ML 180
K + ++LE A K + E + A K + + M QN LS +L
Sbjct: 952 RKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLL 1011
Query: 181 DEILEDVRKAADRLEEEIEEHAFDDNKSVKGVNFEAVLRVEEEEANSKQNITKREVEDD 239
+E + D+ EE+ + NK ++ V +EE++ + KR++E D
Sbjct: 1012 EERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGD 1070
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 43.9 bits (102), Expect = 5e-04
Identities = 51/235 (21%), Positives = 110/235 (46%), Gaps = 18/235 (7%)
Query: 21 QAVEHEEVAQRVIKLHRGRGVAAMQSRQWVRDSCRKLSGLLRQKNAVLNKLKTAIGAVEK 80
+A+E +E +R K+ + + S+ V + +L R + ++KT + +E
Sbjct: 1494 EALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELED 1553
Query: 81 DVGLSDEEKL-FQVHTFEI---FQKELNESENSVFQAVYGLQRALQGDYKDVVNMKESSR 136
++ +++ KL +V+ + F+++L + + LQR L +Y+ +++ +
Sbjct: 1554 ELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLH-EYE--TELEDERK 1610
Query: 137 QR-LEALREAAIKEETEYMELLA--AEKHQVEALKNMQHQNQSLSMLDEILEDVRKAADR 193
QR L A + ++ + + +EL A A K + EA+K ++ + LED R + D
Sbjct: 1611 QRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRD- 1669
Query: 194 LEEEIEEHAFDDNKSVKGVNFEAVLRVEE----EEANSKQNITKREVEDDLGLSM 244
EI A ++ K K + + + E+ E A + ++ K E+ ++L S+
Sbjct: 1670 ---EIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSL 1721
Score = 36.2 bits (82), Expect = 0.10
Identities = 42/186 (22%), Positives = 81/186 (43%), Gaps = 11/186 (5%)
Query: 21 QAVEHEEVAQRVIKLHRGRGVAAMQSRQ----WVRDSCRKLSGLLRQKNAVLNKLKTAIG 76
+ +E EE A++ ++L + A ++ + + D KLS + ++ L T +
Sbjct: 957 EQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLA 1016
Query: 77 AVEKDVGLSDEEKLFQVHTFEIFQKELN-ESENSVFQAVYGLQRALQGDYKDVVNMKESS 135
E++ + KL H I + E+ + E Q + L+R L+GD D
Sbjct: 1017 --EEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADL 1074
Query: 136 RQRLEALREAAIKEETEYMELLAAEKHQV----EALKNMQHQNQSLSMLDEILEDVRKAA 191
+ ++ L+ K+E E LA ++ ALK ++ +S L E L+ R A
Sbjct: 1075 QAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAAR 1134
Query: 192 DRLEEE 197
++ E++
Sbjct: 1135 NKAEKQ 1140
Score = 30.8 bits (68), Expect = 4.3
Identities = 39/149 (26%), Positives = 64/149 (42%), Gaps = 23/149 (15%)
Query: 105 ESENSVFQAVYGLQRALQGDYKDVVNMKESSRQRLE--------ALREAA-IKEETEY-- 153
E + F + ++ + Y D + E+ + E AL EA KEE E
Sbjct: 1447 EKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTN 1506
Query: 154 ------MELLAAEKHQVEALKNMQHQNQSLSMLDEILEDVRKAADRLEEEIEEHAFDDNK 207
ME L + K V KN+ +S L+ +E+++ + LE+E++ A +D K
Sbjct: 1507 KMLKAEMEDLVSSKDDVG--KNVHELEKSKRALETQMEEMKTQLEELEDELQ--ATEDAK 1562
Query: 208 SVKGVNFEAVLRVEEE--EANSKQNITKR 234
VN +A+ E +A +QN KR
Sbjct: 1563 LRLEVNMQALKGQFERDLQARDEQNEEKR 1591
Score = 30.4 bits (67), Expect = 5.6
Identities = 51/239 (21%), Positives = 95/239 (39%), Gaps = 17/239 (7%)
Query: 9 FWVLFPVLPWAVQAVEHEEVAQRVIKLHRGRGVAAMQSRQWVRDSCRKLSGLLRQKNAVL 68
+W LF + +Q EE Q + ++ +++ +K S L +KN +
Sbjct: 834 WWRLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQ 893
Query: 69 NKLKTAIG----AVEKDVGLSDEEKLFQVHTFEIFQKELNESENSVFQAVYGLQRALQGD 124
+L+ A E V L+ +++ + E+ + L E E+ Q LQ +
Sbjct: 894 EQLQAETELYAEAEEMRVRLAAKKQELEEILHEM-EARLEEEEDRGQQ--------LQAE 944
Query: 125 YKDVVNMKESSRQRLEALREAAIKEETEYMELLAAEKHQVEALKNMQHQNQSLS----ML 180
K + ++LE A K + E + A K + + M QN LS +L
Sbjct: 945 RKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLL 1004
Query: 181 DEILEDVRKAADRLEEEIEEHAFDDNKSVKGVNFEAVLRVEEEEANSKQNITKREVEDD 239
+E + D+ EE+ + NK ++ V +EE++ + KR++E D
Sbjct: 1005 EERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGD 1063
>gi|224586773 hypothetical protein LOC643854 [Homo sapiens]
Length = 777
Score = 42.4 bits (98), Expect = 0.001
Identities = 46/187 (24%), Positives = 86/187 (45%), Gaps = 19/187 (10%)
Query: 71 LKTAIGAVEKDVGLSDEEKLFQVHTFEIFQKELNESENSVFQAVYGLQR---ALQGDYKD 127
LK I A + +V L E + + I E+++++ + + + LQ +LQ +
Sbjct: 315 LKKLIHAAKLNVSLKSLEG--ERNHIIIQLSEVDKTKEELTEHIKNLQTQQASLQSENIY 372
Query: 128 VVNMKESSRQRLEALREAAIKEETE-YMELLAAEKHQVEALKNMQHQNQSLSMLDEILED 186
+ + +Q+L+ + E + E + Y +L E +++E + + + +S E LE
Sbjct: 373 FESENQKLQQKLKIMTEFYQENEMKLYRKLTVEENYRIEEEEKLSRVEEKISHATEELET 432
Query: 187 VRKAADRLEEEIEEHAFDDNKSVKGV------NFEAVLRVE-------EEEANSKQNITK 233
RK A LEEE+E K V N+ A E +E A++KQ +T+
Sbjct: 433 YRKLAKDLEEELERTVHFYQKQVISYEKRGHDNWLAARTAERNLSDLRKENAHNKQKLTE 492
Query: 234 REVEDDL 240
RE++ +L
Sbjct: 493 RELKFEL 499
>gi|92859701 myosin VI [Homo sapiens]
Length = 1285
Score = 42.4 bits (98), Expect = 0.001
Identities = 33/141 (23%), Positives = 63/141 (44%), Gaps = 6/141 (4%)
Query: 126 KDVVNMKESSRQRLEALREAAIKEET---EYMELLAAEKHQVEALKNMQHQNQSLSMLDE 182
K + N++ S + ++ + +E EY L+ + + + AL+ + Q + L
Sbjct: 869 KQIKNLEISIDTLMAKIKSTMMTQEQIQKEYDALVKSSEELLSALQKKKQQEEEAERLRR 928
Query: 183 ILEDVRKAADRLEEEIEEHAFDDNKSVKGVNFEAVLRVEEEEANSKQNITKR---EVEDD 239
I E++ K R EE+ + ++ + + EA + EEEE +++ KR EVE
Sbjct: 929 IQEEMEKERKRREEDEKRRRKEEEERRMKLEMEAKRKQEEEERKKREDDEKRIQAEVEAQ 988
Query: 240 LGLSMLIDSQNNQYILTKPRD 260
L +SQ + + RD
Sbjct: 989 LARQKEEESQQQAVLEQERRD 1009
Score = 33.9 bits (76), Expect = 0.51
Identities = 37/158 (23%), Positives = 75/158 (47%), Gaps = 16/158 (10%)
Query: 118 QRALQGDYKDVVNMKESSRQRLEALREAAIKEETEYMELLAAEKHQVEALKNMQHQNQSL 177
Q +Q +Y +V +SS + L AL++ K++ E E L + ++E + + +++
Sbjct: 892 QEQIQKEYDALV---KSSEELLSALQKK--KQQEEEAERLRRIQEEMEKERKRREEDEKR 946
Query: 178 SMLDEILEDVR---KAADRLEEEIEEHAFDDNKSVKGVNFEAVLRVEEEEANSKQNITKR 234
+E ++ +A + EEE + DD K ++ EA L ++EE + +Q + ++
Sbjct: 947 RRKEEEERRMKLEMEAKRKQEEEERKKREDDEKRIQ-AEVEAQLARQKEEESQQQAVLEQ 1005
Query: 235 EVED-DLGLSM------LIDSQNNQYILTKPRDSTIPR 265
E D +L L + LI + + + D T P+
Sbjct: 1006 ERRDRELALRIAQSEAELISDEAQADLALRRNDGTRPK 1043
>gi|21735548 centrosomal protein 2 [Homo sapiens]
Length = 2442
Score = 42.0 bits (97), Expect = 0.002
Identities = 52/221 (23%), Positives = 91/221 (41%), Gaps = 24/221 (10%)
Query: 22 AVEHEEVAQRVIKLHRGRGVAAMQSRQWVRDSCRKLSGLLRQKNAVLNKLKTAIGAVEKD 81
A+ E VA + KLH+ Q+R +RD +KL L A +++ T + +++
Sbjct: 1235 ALSAEAVASALHKLHQDLW-KTQQTRDVLRDQVQKLEERLTDTEAEKSQVHTELQDLQRQ 1293
Query: 82 VGLSDEEKLFQVHTFEIFQKELNESENSVFQAVYGLQRALQGDYKDVVNMKESSRQRLEA 141
+ + EEK +E Q L + + + LQ L + + QR+EA
Sbjct: 1294 LSQNQEEK----SKWEGKQNSLESELMELHETMASLQSRL----------RRAELQRMEA 1339
Query: 142 LREAAIKEETEYMELLAAEKHQVEALKNMQHQNQSLSMLDEILEDVRKAADRLEEEIEE- 200
E + + + L A +H A+ + Q + +L+E L R A EE+E
Sbjct: 1340 QGERELLQAAK-ENLTAQVEHLQAAVVEARAQASAAGILEEDLRTARSALKLKNEEVESE 1398
Query: 201 ----HAFDDNKSVKGVNFEAVLRVEEEEANSKQNITKREVE 237
A + +K +A ++E A Q + +RE E
Sbjct: 1399 RERAQALQEQGELKVAQGKA---LQENLALLTQTLAEREEE 1436
Score = 32.7 bits (73), Expect = 1.1
Identities = 30/117 (25%), Positives = 52/117 (44%), Gaps = 3/117 (2%)
Query: 121 LQGDYKDVVNMKESSRQRLEALREAAIKEETEYMELLAAEKHQVEALKNMQHQNQSLSML 180
LQ D +D+ KE +++L R T+ +L K Q E L + ++L
Sbjct: 678 LQADLRDIQEEKEEIQKKLSESRHQQEAATTQLEQLHQEAKRQEEVLARAVQEKEALVRE 737
Query: 181 DEILEDVRKAADRLEEEIEEHAFDDNKSVKGVNFEAVLRVEEEEANSKQNITKREVE 237
LE +A +R +++ E S K + E+ L E ++ NS +TK ++E
Sbjct: 738 KAALEVRLQAVERDRQDLAEQ-LQGLSSAKEL-LESSL-FEAQQQNSVIEVTKGQLE 791
>gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens]
Length = 2003
Score = 42.0 bits (97), Expect = 0.002
Identities = 51/220 (23%), Positives = 92/220 (41%), Gaps = 11/220 (5%)
Query: 24 EHEEVAQRVIKLHRGRGVAAMQSRQWVRDSCRKLSGLLRQKNAVLNKLKTAIGAVEKDVG 83
E E +R + R A + S+ V S +L R N L+ + +E ++
Sbjct: 1522 EAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELT 1581
Query: 84 LSDEEKLFQVHTFEIFQKELNESENSVFQAVYGLQRALQGDYKDVVNMKESSRQRLEALR 143
+++ KL T + + + +A +R L +D ++ R++
Sbjct: 1582 AAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAV 1641
Query: 144 EAAIKEETEYMELLA----AEKHQVEALKNMQHQNQSLSMLDEILEDVRKAADRLEEEIE 199
A K E E EL A A + + EA+K ++ + L +E+ R + EEI
Sbjct: 1642 AARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTS----REEIF 1697
Query: 200 EHAFDDNKSVKGVNFEAVLRVEEEEANSKQNITKREVEDD 239
+ K +KG+ E VLR++EE A S + +R+ + D
Sbjct: 1698 SQNRESEKRLKGLEAE-VLRLQEELAASDR--ARRQAQQD 1734
>gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens]
Length = 1995
Score = 42.0 bits (97), Expect = 0.002
Identities = 51/220 (23%), Positives = 92/220 (41%), Gaps = 11/220 (5%)
Query: 24 EHEEVAQRVIKLHRGRGVAAMQSRQWVRDSCRKLSGLLRQKNAVLNKLKTAIGAVEKDVG 83
E E +R + R A + S+ V S +L R N L+ + +E ++
Sbjct: 1514 EAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELT 1573
Query: 84 LSDEEKLFQVHTFEIFQKELNESENSVFQAVYGLQRALQGDYKDVVNMKESSRQRLEALR 143
+++ KL T + + + +A +R L +D ++ R++
Sbjct: 1574 AAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAV 1633
Query: 144 EAAIKEETEYMELLA----AEKHQVEALKNMQHQNQSLSMLDEILEDVRKAADRLEEEIE 199
A K E E EL A A + + EA+K ++ + L +E+ R + EEI
Sbjct: 1634 AARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTS----REEIF 1689
Query: 200 EHAFDDNKSVKGVNFEAVLRVEEEEANSKQNITKREVEDD 239
+ K +KG+ E VLR++EE A S + +R+ + D
Sbjct: 1690 SQNRESEKRLKGLEAE-VLRLQEELAASDR--ARRQAQQD 1726
>gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens]
Length = 2036
Score = 42.0 bits (97), Expect = 0.002
Identities = 51/220 (23%), Positives = 92/220 (41%), Gaps = 11/220 (5%)
Query: 24 EHEEVAQRVIKLHRGRGVAAMQSRQWVRDSCRKLSGLLRQKNAVLNKLKTAIGAVEKDVG 83
E E +R + R A + S+ V S +L R N L+ + +E ++
Sbjct: 1555 EAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELT 1614
Query: 84 LSDEEKLFQVHTFEIFQKELNESENSVFQAVYGLQRALQGDYKDVVNMKESSRQRLEALR 143
+++ KL T + + + +A +R L +D ++ R++
Sbjct: 1615 AAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAV 1674
Query: 144 EAAIKEETEYMELLA----AEKHQVEALKNMQHQNQSLSMLDEILEDVRKAADRLEEEIE 199
A K E E EL A A + + EA+K ++ + L +E+ R + EEI
Sbjct: 1675 AARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTS----REEIF 1730
Query: 200 EHAFDDNKSVKGVNFEAVLRVEEEEANSKQNITKREVEDD 239
+ K +KG+ E VLR++EE A S + +R+ + D
Sbjct: 1731 SQNRESEKRLKGLEAE-VLRLQEELAASDR--ARRQAQQD 1767
>gi|51972208 leucine, glutamate and lysine rich 1 [Homo sapiens]
Length = 388
Score = 42.0 bits (97), Expect = 0.002
Identities = 38/164 (23%), Positives = 69/164 (42%), Gaps = 13/164 (7%)
Query: 105 ESENSVFQAVYGLQRALQGDYKDVVN-MKESSRQRLEALREAAIKEETEYMELLAAEKHQ 163
E V Q Q LQ D++ RQ + L+E K T Y E +++ +
Sbjct: 133 EKHQDVIQKYKKEQEELQMKISDLITGATRDLRQEVTTLKEKLHKSHTRYTEESNSKEKE 192
Query: 164 VEALKNMQHQNQS-----LSMLDEILEDVRKAADRLEEEIEEHAFDDNKSVKGVNFEAVL 218
+E LKN+ + +S + D + E++RK ++ +E++ + ++ N
Sbjct: 193 IENLKNLVAEFESRLKKEIDSNDSVSENLRKEMEQKSDELKRVMLAQTQLIEQFN----- 247
Query: 219 RVEEEEANSKQNITKREVEDDLGLSMLIDSQNNQYI-LTKPRDS 261
+EE Q +RE E+ L+ + Q + L+K R S
Sbjct: 248 -QSQEENTFLQETVRRECEERFELTEALSQAREQLLELSKLRGS 290
>gi|146262005 CTAGE family, member 6 [Homo sapiens]
Length = 777
Score = 42.0 bits (97), Expect = 0.002
Identities = 46/187 (24%), Positives = 86/187 (45%), Gaps = 19/187 (10%)
Query: 71 LKTAIGAVEKDVGLSDEEKLFQVHTFEIFQKELNESENSVFQAVYGLQ---RALQGDYKD 127
LK I A + +V L E + + I E+++++ + + + LQ +LQ +
Sbjct: 315 LKKLIHAAKLNVSLKSLEG--ERNHIIIQLSEVDKTKEELTEHIKNLQTQQESLQSENIY 372
Query: 128 VVNMKESSRQRLEALREAAIKEETE-YMELLAAEKHQVEALKNMQHQNQSLSMLDEILED 186
+ + +Q+L+ + E ++E + Y +L E +++E + + + LS E LE
Sbjct: 373 FESENQKLQQKLKIMTEFYQEDEMKLYRKLTVEENYRIEEEEKLSKVEEKLSRATEQLET 432
Query: 187 VRKAADRLEEEIEEHAFDDNKSVKGV------NFEAVLRVE-------EEEANSKQNITK 233
RK A LEEE+E K V N+ A E +E A++KQ +T+
Sbjct: 433 YRKLAKDLEEELERTVHFYQKQVISYEKRGHDNWLAARTAERNLSDLRKENAHNKQKLTE 492
Query: 234 REVEDDL 240
E++ +L
Sbjct: 493 TELKFEL 499
>gi|110815815 centlein isoform 1 [Homo sapiens]
Length = 1406
Score = 41.6 bits (96), Expect = 0.002
Identities = 51/235 (21%), Positives = 107/235 (45%), Gaps = 14/235 (5%)
Query: 24 EHEEVAQRVIKLHRGRGVAAMQSRQWVRDSCRKLSGLLRQKNAVLNKLKTAIGAVEKDVG 83
E++EV ++++ + SRQ ++ L+GL ++K +L KL+++ +
Sbjct: 1011 EYKEVNEKLLHQQQVSDQRFQTSRQTIKKLNLDLAGLRKEKEDLLKKLESS----SEITS 1066
Query: 84 LSDEEKLFQVHTFEIFQKELNES-ENSVFQAVYGLQRALQGDYKDVVNMKESSRQRLEAL 142
L++E ++ + S + + Q Y L+ A K N+K + L
Sbjct: 1067 LAEENSQVTFPRIQVTSLSPSRSMDLEMKQLQYKLKNATNELTKQSSNVKTLKFELL--A 1124
Query: 143 REAAIKEETEYMEL----LAAEKHQVEALKNMQHQN-QSLSMLDEILEDVRKAADRLEEE 197
+E IKE E + + ++H +E LK Q N +S E+L+++ K L EE
Sbjct: 1125 KEEHIKEMHEKISRMERDITMKRHLIEDLKFRQKVNLESNKSFSEMLQNLDKKVKTLTEE 1184
Query: 198 I--EEHAFDDNKSVKGVNFEAVLRVEEEEANSKQNITKREVEDDLGLSMLIDSQN 250
++ + D K V + + E+ SK+ + K++++ L +S + ++++
Sbjct: 1185 CSNKKVSIDSLKQRLNVAVKEKSQYEQMYQKSKEELEKKDLKLTLLVSRISETES 1239
>gi|70166430 GRINL1A combined protein isoform 2 [Homo sapiens]
Length = 445
Score = 41.2 bits (95), Expect = 0.003
Identities = 32/178 (17%), Positives = 93/178 (52%), Gaps = 11/178 (6%)
Query: 64 KNAVLNKLKTAIGAVEKDVGLSDEEKLFQVHTFE--IFQKELNESENSVFQAVYGLQRAL 121
K+ + N +T +++K L ++++ +V E + + ++ S+ + + + + + L
Sbjct: 189 KDQIRNLQQTYEASMDK---LREKQRQLEVAQVENQLLKMKVESSQEANAEVMREMTKKL 245
Query: 122 QGDYKDVVNMKESSRQRLEALREAAIKEETEYMELLAAEKHQVEALK-NMQHQNQSLSML 180
Y++ ++E R+ A +EA ++E +++ + +++A + +++ ++Q + L
Sbjct: 246 YSQYEE--KLQEEQRKH-SAEKEALLEETNSFLKAIEEANKKMQAAEISLEEKDQRIGEL 302
Query: 181 DEILEDVRKAADRLEEEIEEHAFDDNKSVKGVNFEAVLRVEEEEANSKQNITKREVED 238
D ++E + K +L+ ++ EH + + + + E ++EE A+ ++ I R ++D
Sbjct: 303 DRLIERMEKERHQLQLQLLEHETEMSGELTDSDKERYQQLEEASASLRERI--RHLDD 358
>gi|70166414 GRINL1A combined protein isoform 1 [Homo sapiens]
Length = 550
Score = 41.2 bits (95), Expect = 0.003
Identities = 32/178 (17%), Positives = 93/178 (52%), Gaps = 11/178 (6%)
Query: 64 KNAVLNKLKTAIGAVEKDVGLSDEEKLFQVHTFE--IFQKELNESENSVFQAVYGLQRAL 121
K+ + N +T +++K L ++++ +V E + + ++ S+ + + + + + L
Sbjct: 189 KDQIRNLQQTYEASMDK---LREKQRQLEVAQVENQLLKMKVESSQEANAEVMREMTKKL 245
Query: 122 QGDYKDVVNMKESSRQRLEALREAAIKEETEYMELLAAEKHQVEALK-NMQHQNQSLSML 180
Y++ ++E R+ A +EA ++E +++ + +++A + +++ ++Q + L
Sbjct: 246 YSQYEE--KLQEEQRKH-SAEKEALLEETNSFLKAIEEANKKMQAAEISLEEKDQRIGEL 302
Query: 181 DEILEDVRKAADRLEEEIEEHAFDDNKSVKGVNFEAVLRVEEEEANSKQNITKREVED 238
D ++E + K +L+ ++ EH + + + + E ++EE A+ ++ I R ++D
Sbjct: 303 DRLIERMEKERHQLQLQLLEHETEMSGELTDSDKERYQQLEEASASLRERI--RHLDD 358
>gi|111494235 GRINL1A combined protein isoform 8 [Homo sapiens]
Length = 438
Score = 41.2 bits (95), Expect = 0.003
Identities = 32/178 (17%), Positives = 93/178 (52%), Gaps = 11/178 (6%)
Query: 64 KNAVLNKLKTAIGAVEKDVGLSDEEKLFQVHTFE--IFQKELNESENSVFQAVYGLQRAL 121
K+ + N +T +++K L ++++ +V E + + ++ S+ + + + + + L
Sbjct: 189 KDQIRNLQQTYEASMDK---LREKQRQLEVAQVENQLLKMKVESSQEANAEVMREMTKKL 245
Query: 122 QGDYKDVVNMKESSRQRLEALREAAIKEETEYMELLAAEKHQVEALK-NMQHQNQSLSML 180
Y++ ++E R+ A +EA ++E +++ + +++A + +++ ++Q + L
Sbjct: 246 YSQYEE--KLQEEQRKH-SAEKEALLEETNSFLKAIEEANKKMQAAEISLEEKDQRIGEL 302
Query: 181 DEILEDVRKAADRLEEEIEEHAFDDNKSVKGVNFEAVLRVEEEEANSKQNITKREVED 238
D ++E + K +L+ ++ EH + + + + E ++EE A+ ++ I R ++D
Sbjct: 303 DRLIERMEKERHQLQLQLLEHETEMSGELTDSDKERYQQLEEASASLRERI--RHLDD 358
>gi|70166580 GRINL1A upstream protein isoform 7 [Homo sapiens]
Length = 466
Score = 41.2 bits (95), Expect = 0.003
Identities = 32/178 (17%), Positives = 93/178 (52%), Gaps = 11/178 (6%)
Query: 64 KNAVLNKLKTAIGAVEKDVGLSDEEKLFQVHTFE--IFQKELNESENSVFQAVYGLQRAL 121
K+ + N +T +++K L ++++ +V E + + ++ S+ + + + + + L
Sbjct: 189 KDQIRNLQQTYEASMDK---LREKQRQLEVAQVENQLLKMKVESSQEANAEVMREMTKKL 245
Query: 122 QGDYKDVVNMKESSRQRLEALREAAIKEETEYMELLAAEKHQVEALK-NMQHQNQSLSML 180
Y++ ++E R+ A +EA ++E +++ + +++A + +++ ++Q + L
Sbjct: 246 YSQYEE--KLQEEQRKH-SAEKEALLEETNSFLKAIEEANKKMQAAEISLEEKDQRIGEL 302
Query: 181 DEILEDVRKAADRLEEEIEEHAFDDNKSVKGVNFEAVLRVEEEEANSKQNITKREVED 238
D ++E + K +L+ ++ EH + + + + E ++EE A+ ++ I R ++D
Sbjct: 303 DRLIERMEKERHQLQLQLLEHETEMSGELTDSDKERYQQLEEASASLRERI--RHLDD 358
>gi|56847634 hypothetical protein LOC441294 [Homo sapiens]
Length = 777
Score = 41.2 bits (95), Expect = 0.003
Identities = 46/187 (24%), Positives = 85/187 (45%), Gaps = 19/187 (10%)
Query: 71 LKTAIGAVEKDVGLSDEEKLFQVHTFEIFQKELNESENSVFQAVYGLQR---ALQGDYKD 127
LK I A + +V L E + + I E+++++ + + + LQ +LQ +
Sbjct: 315 LKKLIHAAKLNVSLKSLEG--ERNHIIIQLSEVDKTKEELTEHIKNLQTQQASLQSENIY 372
Query: 128 VVNMKESSRQRLEALREAAIKEETE-YMELLAAEKHQVEALKNMQHQNQSLSMLDEILED 186
+ + +Q+L+ + E + E + Y +L E +++E + + + LS E LE
Sbjct: 373 FESENQKLQQKLKIMTEFYQENEMKLYRKLTVEENYRIEEEEKLSRVEEKLSRATEQLET 432
Query: 187 VRKAADRLEEEIEEHAFDDNKSVKGV------NFEAVLRVE-------EEEANSKQNITK 233
RK A LEEE+E K V N+ A E +E A++KQ +T+
Sbjct: 433 YRKLAKDLEEELERTVHFYQKQVISYEKRGHDNWLAARTAERNLSDLRKENAHNKQKLTE 492
Query: 234 REVEDDL 240
E++ +L
Sbjct: 493 TELKFEL 499
>gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo
sapiens]
Length = 1939
Score = 40.8 bits (94), Expect = 0.004
Identities = 56/248 (22%), Positives = 110/248 (44%), Gaps = 31/248 (12%)
Query: 24 EHEEVAQRVIKLHRGRGVAAMQSRQWVRDSCRKLSGLLRQKNAVLN---KLKTAIGAVEK 80
E EE+ + + RGR +A Q + D+ ++ L Q +++N KL+T I ++
Sbjct: 1688 EVEELRASLERTERGRKMA----EQELLDASERVQLLHTQNTSLINTKKKLETDISQIQG 1743
Query: 81 DV------GLSDEEKLFQVHTFEIFQKELNESENSVFQAVYGLQRALQGDYKDV-VNMKE 133
++ + EEK + T E + E + +++ ++ KD+ + + E
Sbjct: 1744 EMEDIVQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDE 1803
Query: 134 SSRQRLEALREAAIKEETEYMELLAA----EKHQVEALKNMQHQNQSLSMLDEILEDVRK 189
+ + L+ ++ K E EL + +KH VEA+K ++ + + L E+ RK
Sbjct: 1804 AEQLALKGGKKQIQKLEARVRELESEVESEQKHNVEAVKGLRKHERRVKELTYQTEEDRK 1863
Query: 190 AADRLEEEIEEHAFDDNKSVKGVNFEAVLRVEEEEANSKQNITK-----REVEDDLGLSM 244
RL++ +++ VK +A EE E S N+ K E+E+ +
Sbjct: 1864 NILRLQDLVDKL----QTKVKAYKRQA----EEAEEQSNVNLAKFRKLQHELEEAKERAD 1915
Query: 245 LIDSQNNQ 252
+ +SQ N+
Sbjct: 1916 IAESQVNK 1923
Score = 35.0 bits (79), Expect = 0.23
Identities = 34/117 (29%), Positives = 55/117 (47%), Gaps = 20/117 (17%)
Query: 126 KDVVNMKESSRQRLEALR--EAAIKEETEYMELLAAEKHQVEALKNMQHQNQSLSMLDEI 183
K++ NMKE + E L EA KE E M L EK+ ++ +Q + +L+ +E
Sbjct: 851 KEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQL--QVQAEADALADAEER 908
Query: 184 LEDVRKAADRLEEEIEEHAFDDNKSVKGVNFEAVLRVE-EEEANSKQNITKREVEDD 239
+ + K +LE +I+E R E EEE N++ KR++ED+
Sbjct: 909 CDQLIKTKIQLEAKIKE---------------VTERAEDEEEINAELTAKKRKLEDE 950
Score = 32.0 bits (71), Expect = 1.9
Identities = 50/214 (23%), Positives = 94/214 (43%), Gaps = 31/214 (14%)
Query: 63 QKNAVLNKLKTAIGAVEKDVG--LSDEEKLFQVHTFEIFQK------ELNESENSVFQAV 114
+K+ + L+ A ++E + G L + +L QV + EI +K EL++ + + + V
Sbjct: 1540 EKSELQTSLEEAEASLEHEEGKILRIQLELNQVKS-EIDRKIAEKDEELDQLKRNHLRVV 1598
Query: 115 YGLQRALQGDYKDVVNMKESSRQRLEALREAAIKEETE------YMELLAAEKHQVEALK 168
+Q L + R R +ALR IK++ E ++L A + EAL+
Sbjct: 1599 ESMQSTLDAEI----------RSRNDALR---IKKKMEGDLNEMEIQLNHANRQAAEALR 1645
Query: 169 NMQHQNQSLSMLDEILEDVRKAADRLEEEIEEHAFDDNKSVKGVNFEAVLRVEEEEANSK 228
N+++ L L+D + D L+E++ + ++ E LR E
Sbjct: 1646 NLRNTQGILKDTQLHLDDAIRGQDDLKEQLA--MVERRANLMQAEVEE-LRASLERTERG 1702
Query: 229 QNITKREVEDDLGLSMLIDSQNNQYILTKPRDST 262
+ + ++E+ D L+ +QN I TK + T
Sbjct: 1703 RKMAEQELLDASERVQLLHTQNTSLINTKKKLET 1736
Score = 30.8 bits (68), Expect = 4.3
Identities = 46/221 (20%), Positives = 86/221 (38%), Gaps = 29/221 (13%)
Query: 79 EKDVGLSDEEKLFQVHTFEIFQKELNESENSVFQAVYGLQRALQGDYKDVVNMKESSRQR 138
EKD +S + Q T +I +EL +A L ALQ D ++E +
Sbjct: 1297 EKDAMVSQLSRGKQAFTQQI--EELKRQLEEETKAKSTLAHALQSARHDCDLLREQYEEE 1354
Query: 139 LEA---LREAAIKEETEYMELLAAEKHQVEALKNMQHQNQSLSMLDEILED--------- 186
EA L+ K +E + K++ +A++ + ++ L + L+D
Sbjct: 1355 QEAKAELQRGMSKANSEVAQWRT--KYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVN 1412
Query: 187 -----VRKAADRLEEEIEEHAFDDNKS--------VKGVNFEAVLRVEEEEANSKQNITK 233
+ K RL+ E+E+ D +S K NF+ VL +++ Q +
Sbjct: 1413 SKCASLEKTKQRLQNEVEDLMIDVERSNAACIALDKKQRNFDKVLAEWKQKYEETQAELE 1472
Query: 234 REVEDDLGLSMLIDSQNNQYILTKPRDSTIPRADHHFIKDI 274
++ LS + N Y + T+ R + + ++I
Sbjct: 1473 ASQKESRSLSTELFKVKNAYEESLDHLETLKRENKNLQQEI 1513
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 40.4 bits (93), Expect = 0.005
Identities = 46/184 (25%), Positives = 89/184 (48%), Gaps = 26/184 (14%)
Query: 60 LLRQKNAVLNKLKTAIGAVEKDVGLSDEEKLFQVHTFEIFQKELNESENSVFQAVYGLQR 119
L R++ + NK++ I EK +E KL + H+ I +E E +
Sbjct: 2139 LARKQRKLANKMRRMINKEEKMT--EEESKLARKHSEVILD---DEEEGGI--------- 2184
Query: 120 ALQGDYKDVVN-MKESSRQRLEALREAAIKEE-TEYMELLAAEKH---QVEALKNMQHQN 174
+ ++V+ +K R+R EA R KE+ + ++ + +E+H ++E+L + +
Sbjct: 2185 ----EEEEVIPFLKRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQ 2240
Query: 175 QSLSMLDEILEDVRKAADRLEEEIEEHAFDDNKSVKGVNFEAVLRVEEEEANSKQNITKR 234
+SLS +E E+ + +R EEE+ E + + +G + V + EEE+ K+ K
Sbjct: 2241 ESLSSEEE--EEREEEEEREEEEVREEEEERKEEEEGEE-KQVEKEEEEKKKKKKEKKKE 2297
Query: 235 EVED 238
EV++
Sbjct: 2298 EVQE 2301
Score = 33.1 bits (74), Expect = 0.86
Identities = 21/114 (18%), Positives = 56/114 (49%), Gaps = 5/114 (4%)
Query: 70 KLKTAIGAVEKDVGLSDEEKLFQVHTFEIFQKELNESENSVFQAVYGLQRALQGDYKDVV 129
++++ + +EK LS EE+ + E ++E+ E E + G ++ ++ + ++
Sbjct: 2229 EMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKK 2288
Query: 130 NMKESSRQRLEALREAAIKEETEYMELLAAEKHQVEALKNMQHQNQSLSMLDEI 183
K+ ++ +E +E+ E M + + E+L + + + +S S+ +E+
Sbjct: 2289 KKKKEKKKEEVQEKEEVFEEKEEIM-----SEEETESLSDEEEEEESCSLEEEV 2337
>gi|239735588 TRAF2 and NCK interacting kinase isoform 6 [Homo
sapiens]
Length = 1297
Score = 40.4 bits (93), Expect = 0.005
Identities = 44/175 (25%), Positives = 78/175 (44%), Gaps = 26/175 (14%)
Query: 70 KLKTAIGAVEKDVGLSDEEKLFQVHTFEIFQKELNESENSVFQAVYGLQRALQGDYKDVV 129
+LK I +K G DE + +E E E EN G+ ++
Sbjct: 301 QLKDHIDRTKKKRGEKDETE------YEYSGSEEEEEEND------------SGEPSSIL 342
Query: 130 NMKESSRQRLEALR-EAAIKEETEYMELLAAEKHQVEALKNMQHQNQSLSMLDEILEDVR 188
N+ S R + LR + A KE +E + E+ Q E N +H+ Q L+ + +E+ +
Sbjct: 343 NLPGESTLRRDFLRLQLANKERSEALRRQQLEQQQRE---NEEHKRQLLAERQKRIEEQK 399
Query: 189 KAADRLEEE--IEEHAFDDNKSVKGVNFEAVLRVEEE--EANSKQNITKREVEDD 239
+ RLEE+ E+ + + ++E +R EEE A +Q +R++E++
Sbjct: 400 EQRRRLEEQQRREKELRKQQEREQRRHYEEQMRREEERRRAEHEQEYIRRQLEEE 454
>gi|239735586 TRAF2 and NCK interacting kinase isoform 5 [Homo
sapiens]
Length = 1305
Score = 40.4 bits (93), Expect = 0.005
Identities = 44/175 (25%), Positives = 78/175 (44%), Gaps = 26/175 (14%)
Query: 70 KLKTAIGAVEKDVGLSDEEKLFQVHTFEIFQKELNESENSVFQAVYGLQRALQGDYKDVV 129
+LK I +K G DE + +E E E EN G+ ++
Sbjct: 301 QLKDHIDRTKKKRGEKDETE------YEYSGSEEEEEEND------------SGEPSSIL 342
Query: 130 NMKESSRQRLEALR-EAAIKEETEYMELLAAEKHQVEALKNMQHQNQSLSMLDEILEDVR 188
N+ S R + LR + A KE +E + E+ Q E N +H+ Q L+ + +E+ +
Sbjct: 343 NLPGESTLRRDFLRLQLANKERSEALRRQQLEQQQRE---NEEHKRQLLAERQKRIEEQK 399
Query: 189 KAADRLEEE--IEEHAFDDNKSVKGVNFEAVLRVEEE--EANSKQNITKREVEDD 239
+ RLEE+ E+ + + ++E +R EEE A +Q +R++E++
Sbjct: 400 EQRRRLEEQQRREKELRKQQEREQRRHYEEQMRREEERRRAEHEQEYIRRQLEEE 454
>gi|239735580 TRAF2 and NCK interacting kinase isoform 2 [Homo
sapiens]
Length = 1352
Score = 40.4 bits (93), Expect = 0.005
Identities = 44/175 (25%), Positives = 78/175 (44%), Gaps = 26/175 (14%)
Query: 70 KLKTAIGAVEKDVGLSDEEKLFQVHTFEIFQKELNESENSVFQAVYGLQRALQGDYKDVV 129
+LK I +K G DE + +E E E EN G+ ++
Sbjct: 301 QLKDHIDRTKKKRGEKDETE------YEYSGSEEEEEEND------------SGEPSSIL 342
Query: 130 NMKESSRQRLEALR-EAAIKEETEYMELLAAEKHQVEALKNMQHQNQSLSMLDEILEDVR 188
N+ S R + LR + A KE +E + E+ Q E N +H+ Q L+ + +E+ +
Sbjct: 343 NLPGESTLRRDFLRLQLANKERSEALRRQQLEQQQRE---NEEHKRQLLAERQKRIEEQK 399
Query: 189 KAADRLEEE--IEEHAFDDNKSVKGVNFEAVLRVEEE--EANSKQNITKREVEDD 239
+ RLEE+ E+ + + ++E +R EEE A +Q +R++E++
Sbjct: 400 EQRRRLEEQQRREKELRKQQEREQRRHYEEQMRREEERRRAEHEQEYIRRQLEEE 454
>gi|55741807 TRAF2 and NCK interacting kinase isoform 1 [Homo
sapiens]
Length = 1360
Score = 40.4 bits (93), Expect = 0.005
Identities = 44/175 (25%), Positives = 78/175 (44%), Gaps = 26/175 (14%)
Query: 70 KLKTAIGAVEKDVGLSDEEKLFQVHTFEIFQKELNESENSVFQAVYGLQRALQGDYKDVV 129
+LK I +K G DE + +E E E EN G+ ++
Sbjct: 301 QLKDHIDRTKKKRGEKDETE------YEYSGSEEEEEEND------------SGEPSSIL 342
Query: 130 NMKESSRQRLEALR-EAAIKEETEYMELLAAEKHQVEALKNMQHQNQSLSMLDEILEDVR 188
N+ S R + LR + A KE +E + E+ Q E N +H+ Q L+ + +E+ +
Sbjct: 343 NLPGESTLRRDFLRLQLANKERSEALRRQQLEQQQRE---NEEHKRQLLAERQKRIEEQK 399
Query: 189 KAADRLEEE--IEEHAFDDNKSVKGVNFEAVLRVEEE--EANSKQNITKREVEDD 239
+ RLEE+ E+ + + ++E +R EEE A +Q +R++E++
Sbjct: 400 EQRRRLEEQQRREKELRKQQEREQRRHYEEQMRREEERRRAEHEQEYIRRQLEEE 454
>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
sapiens]
Length = 1938
Score = 40.4 bits (93), Expect = 0.005
Identities = 57/224 (25%), Positives = 93/224 (41%), Gaps = 37/224 (16%)
Query: 53 SCRKLSGLLRQKNAVLNKLKTAIGAVEKDVGLSDEEKLFQVHTFEIFQKELNESENSV-- 110
S + L K + KLK + + D+E QVH+ + FQK++ E + +
Sbjct: 1066 SQESIMDLENDKQQIEEKLKKKEFELSQLQAKIDDE---QVHSLQ-FQKKIKELQARIEE 1121
Query: 111 ----FQAVYGLQRALQGDYKDVVNMKESSRQRLE-------ALREAAIKEETEYMELL-- 157
+A + L+ ++ D+ E +RLE A E K E E+ ++
Sbjct: 1122 LEEEIEAEHTLRAKIEKQRSDLARELEEISERLEEASGATSAQIEMNKKREAEFQKMRRD 1181
Query: 158 ---AAEKHQVEALKNMQHQNQSLSMLDEILEDVRKAADRLEEEIEE--HAFDDNKSVKGV 212
A +H+ A + Q S++ L E ++++++ +LE+E E DD S
Sbjct: 1182 LEEATLQHEATAATLRKKQADSVAELGEQIDNLQRVKQKLEKEKSELKMEIDDMAS---- 1237
Query: 213 NFEAVLRVEEEEANSKQNI--TKREVEDDLGLSMLIDSQNNQYI 254
N EA+ + SK NI T R VED D Q Q I
Sbjct: 1238 NIEAL-------SKSKSNIERTCRTVEDQFSEIKAKDEQQTQLI 1274
Score = 34.3 bits (77), Expect = 0.39
Identities = 35/134 (26%), Positives = 60/134 (44%), Gaps = 19/134 (14%)
Query: 126 KDVVNMKESSRQRLEALR--EAAIKEETEYMELLAAEKHQVEALKNMQHQNQSLSMLDEI 183
K++ MKE + E L EA KE E M L EK+ ++ +Q + ++L +E
Sbjct: 851 KEMATMKEDFERTKEELARSEARRKELEEKMVSLLQEKNDLQL--QVQSETENLMDAEER 908
Query: 184 LEDVRKAADRLEEEIEEHAFDDNKSVKGVNFEAVLRVEEEEANSKQNITKREVEDDLGLS 243
E + K+ LE +++E R+EEEE + + + K+ +D S
Sbjct: 909 CEGLIKSKILLEAKVKE---------------LTERLEEEEEMNSELVAKKRNLEDKCSS 953
Query: 244 MLIDSQNNQYILTK 257
+ D + + LTK
Sbjct: 954 LKRDIDDLELTLTK 967
Score = 30.0 bits (66), Expect = 7.3
Identities = 36/157 (22%), Positives = 72/157 (45%), Gaps = 23/157 (14%)
Query: 101 KELNESENSVFQAVYGLQRALQGDYKDVVNMKESSRQRLEALREAAIKEETEYMELLAAE 160
+E E+ NS ++ ++ LQG+ +D++ E S L K++ + ++LA
Sbjct: 1405 EENTETANSKCASLEKTKQRLQGEVEDLMRDLERSHTACATLD----KKQRNFDKVLAEW 1460
Query: 161 KHQVEA----LKNMQHQNQSLSM--------LDEI---LEDVRKAADRLEEEIEEHAFDD 205
K +++ L+ Q +++SLS +E+ LE +R+ L+EEI + +
Sbjct: 1461 KQKLDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQLETLRRENKNLQEEISD--LTE 1518
Query: 206 NKSVKGVNFEAVLRVEE--EEANSKQNITKREVEDDL 240
+ G N + + ++ E+ S + EVE L
Sbjct: 1519 QIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSL 1555
>gi|193290160 CTAGE family, member 4 [Homo sapiens]
Length = 777
Score = 40.0 bits (92), Expect = 0.007
Identities = 45/187 (24%), Positives = 85/187 (45%), Gaps = 19/187 (10%)
Query: 71 LKTAIGAVEKDVGLSDEEKLFQVHTFEIFQKELNESENSVFQAVYGLQR---ALQGDYKD 127
LK I A + +V L E + + I E+++++ + + + LQ +LQ +
Sbjct: 315 LKKLIHAAKLNVSLKSLEG--ERNHIIIQLSEVDKTKEELTEHIKNLQTQQASLQSENIY 372
Query: 128 VVNMKESSRQRLEALREAAIKEETE-YMELLAAEKHQVEALKNMQHQNQSLSMLDEILED 186
+ + +Q+L+ + E + E + Y +L E +++E + + + +S E LE
Sbjct: 373 FESENQKLQQKLKIMTEFYQENEMKLYRKLTVEENYRIEEEEKLSRVEEKISRATEGLET 432
Query: 187 VRKAADRLEEEIEEHAFDDNKSVKGV------NFEAVLRVE-------EEEANSKQNITK 233
RK A LEEE+E K V N+ A E +E A++KQ +T+
Sbjct: 433 YRKLAKDLEEELERTVHFYQKQVISYEKRGHDNWLAARTAERNLSDLRKENAHNKQKLTE 492
Query: 234 REVEDDL 240
E++ +L
Sbjct: 493 TELKFEL 499
>gi|27734883 tripartite motif family-like 2 [Homo sapiens]
Length = 387
Score = 40.0 bits (92), Expect = 0.007
Identities = 49/216 (22%), Positives = 92/216 (42%), Gaps = 33/216 (15%)
Query: 114 VYGLQRALQGDYKDVVNMKESSRQRLEAL---------REAAIKEETEYMELLAAEKHQV 164
V G+Q A + K + +SR++LEA R A I+EE + + + ++ +
Sbjct: 2 VCGIQEAAENYRKLFQEILNTSREKLEAAKSILTDEQERMAMIQEEEQNFKKMIESEYSM 61
Query: 165 -------EALKNMQHQNQSLSMLDEILEDVRKAADRLEEEIEEHAFDDNKSVKGVNFEAV 217
E +N+Q Q + +S L+ + E + A +L E+EE + + + V E +
Sbjct: 62 RLRLLNEECEQNLQRQQECISDLN-LRETLLNQAIKLATELEEMFQEMLQRLGRVGRENM 120
Query: 218 LRVEEEEANSKQNITKR-----EVEDDLGLSMLIDSQNNQYILTKPRDSTIPRADHHFIK 272
+++E EA + + + E+E G L +N +Y L + + + + I
Sbjct: 121 EKLKESEARASEQVRSLLKLIVELEKKCGEGTLALLKNAKYSLERSKSLLLEHLEPAHIT 180
Query: 273 DIVTIGMLSLPCGWLCTAIGLPTMFGYIICGVLLGP 308
D+ LC GL +MF + + L P
Sbjct: 181 DLS-----------LCHIRGLSSMFRVLQRHLTLDP 205
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 40.0 bits (92), Expect = 0.007
Identities = 46/219 (21%), Positives = 96/219 (43%), Gaps = 25/219 (11%)
Query: 56 KLSGLLRQKNAVLNKLKTAIGAVEKDVGLSDEEKLFQVHTFEIFQKELNESENSVFQAVY 115
KL L +Q + KL+ EK+ L D+E +FQ H E+ +K L + + +
Sbjct: 630 KLQVLKQQYQTEMEKLREKCEQ-EKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTEL-- 686
Query: 116 GLQRALQGDYKDVVNMKESSRQRLEALREAAIKEETEYMELLAAEK--HQVEALKNMQHQ 173
+L + +V+ + + L L++ K + E + +K HQ + ++
Sbjct: 687 ---ESLSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEH 743
Query: 174 NQSLSMLDEILEDVRKAADRLEEEIEEHAFDDNKSVKGVNFEAVLRVEE---EEANSKQN 230
S+ ++ L+D + L +E ++H + V+ N EA ++ E ++A++K +
Sbjct: 744 EVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVE--NLEADIKRSEGELQQASAKLD 801
Query: 231 ITK----------REVEDDLG--LSMLIDSQNNQYILTK 257
+ + + E+ L L+D + + +LTK
Sbjct: 802 VFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTK 840
Score = 38.5 bits (88), Expect = 0.021
Identities = 46/194 (23%), Positives = 86/194 (44%), Gaps = 21/194 (10%)
Query: 56 KLSGLLRQKNAVLNKLKTAIGAVEKDVGLSDEEKLFQVHTFEIFQKELN-ESENSVFQAV 114
KL+G R+K KL I ++KD+ + +E ++ EI +KE + E E + Q
Sbjct: 1931 KLAGAEREKQ----KLGKEIVRLQKDLRMLRKEHQQEL---EILKKEYDQEREEKIKQEQ 1983
Query: 115 YGLQRALQGDYKDVVNMKESSRQRLEALREAAIKEETEYMELLAAEKHQVEALKNMQHQ- 173
L+ K ++ + + E E IKE A++ + E L++ Q +
Sbjct: 1984 EDLELKHNSTLKQLMREFNTQLAQKEQELEMTIKETIN-----KAQEVEAELLESHQEET 2038
Query: 174 NQSLSMLDEILEDVRKAADRLEEEIEEHAFDDNKSVKGVNFEAV-------LRVEEEEAN 226
NQ L + E +D+++ A R EE ++ + V+ + + ++E+EE
Sbjct: 2039 NQLLKKIAEKDDDLKRTAKRYEEILDAREEEMTAKVRDLQTQLEELQKKYQQKLEQEENP 2098
Query: 227 SKQNITKREVEDDL 240
N+T E++ L
Sbjct: 2099 GNDNVTIMELQTQL 2112
Score = 32.3 bits (72), Expect = 1.5
Identities = 37/153 (24%), Positives = 66/153 (43%), Gaps = 21/153 (13%)
Query: 101 KELNESENSVFQAVYGLQRALQGDYKDVVNMKESSRQRLEALREAAIKEETEYMELLAAE 160
KE E ++ VY ++ L+ K++ ++ S + + E L+ + E+E LA
Sbjct: 1581 KEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESESAAKLAEL 1640
Query: 161 KHQVEALKNMQHQNQSLSMLDEILEDVRKAADR---------LEEEIEEHAFDDN-KSVK 210
K + E K + Q LS ++E E +K + E E E H ++ KSV+
Sbjct: 1641 KRKAEQ-KIAAIKKQLLSQMEEKEEQYKKGTESHLSELNTKLQEREREVHILEEKLKSVE 1699
Query: 211 GVNFEAVL----------RVEEEEANSKQNITK 233
E ++ E+EEA+S+ + K
Sbjct: 1700 SSQSETLIVPRSAKNVAAYTEQEEADSQGCVQK 1732
>gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta [Homo
sapiens]
Length = 1983
Score = 40.0 bits (92), Expect = 0.007
Identities = 53/238 (22%), Positives = 101/238 (42%), Gaps = 25/238 (10%)
Query: 24 EHEEVAQRVIKLHRGRGVAAMQSRQW----VRDSCRKLSGLLRQKNAVLNKLKTAIGAVE 79
+HEE A+ +L R A + QW D+ ++ L K + +L+ A VE
Sbjct: 1395 QHEEEAEAQAELQRLLSKANAEVAQWRSKYEADAIQRTEELEEAKKKLALRLQEAEEGVE 1454
Query: 80 ----KDVGLSDEEKLFQVHTFEIFQKELNESENSVFQAVYGLQRALQGDYKDVVNMKESS 135
K L + Q + ++ EL E S A+ QR L+ ++ +E
Sbjct: 1455 AANAKCSSLEKAKLRLQTESEDV-TLEL-ERATSAAAALDKKQRHLERALEERRRQEEEM 1512
Query: 136 RQRLEALREAAIKEETEYMELLAAEKHQVEALKNMQHQNQSL-----SMLDEI------- 183
++ LEA + + TE L + +EAL+ ++ +N++L + D++
Sbjct: 1513 QRELEAAQRESRGLGTELFRLRHGHEEALEALETLKRENKNLQEEISDLTDQVSLSGKSI 1572
Query: 184 --LEDVRKAADRLEEEIEEHAFDDNKSVKGVNFEAVLRVEEEEANSKQNITKREVEDD 239
LE +KA + + EI+ A ++ + + LR++ E + K + ++ E D
Sbjct: 1573 QELEKTKKALEGEKSEIQA-ALEEAEGALELEETKTLRIQLELSQVKAEVDRKLAEKD 1629
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.324 0.138 0.393
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,588,356
Number of Sequences: 37866
Number of extensions: 866585
Number of successful extensions: 4066
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 24
Number of HSP's successfully gapped in prelim test: 341
Number of HSP's that attempted gapping in prelim test: 3549
Number of HSP's gapped (non-prelim): 831
length of query: 677
length of database: 18,247,518
effective HSP length: 109
effective length of query: 568
effective length of database: 14,120,124
effective search space: 8020230432
effective search space used: 8020230432
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.