Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 157168329
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|157168329 formin 1 [Homo sapiens]
(1196 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|157168329 formin 1 [Homo sapiens] 2399 0.0
gi|160707881 formin 2 [Homo sapiens] 558 e-158
gi|119395760 diaphanous 1 isoform 2 [Homo sapiens] 229 9e-60
gi|119395758 diaphanous 1 isoform 1 [Homo sapiens] 229 9e-60
gi|32880208 diaphanous homolog 3 isoform b [Homo sapiens] 200 6e-51
gi|110225351 diaphanous homolog 3 isoform a [Homo sapiens] 200 6e-51
gi|21071077 dishevelled-associated activator of morphogenesis 1 ... 192 2e-48
gi|33356148 formin-like 1 [Homo sapiens] 189 2e-47
gi|6382071 diaphanous 2 isoform 12C [Homo sapiens] 187 4e-47
gi|5803003 diaphanous 2 isoform 156 [Homo sapiens] 187 4e-47
gi|40548415 dishevelled associated activator of morphogenesis 2 ... 184 6e-46
gi|52485606 formin-like 2 [Homo sapiens] 179 2e-44
gi|149999378 inverted formin 2 isoform 2 [Homo sapiens] 168 2e-41
gi|149999380 inverted formin 2 isoform 1 [Homo sapiens] 168 2e-41
gi|145309324 FH2 domain containing 1 [Homo sapiens] 152 2e-36
gi|119120861 formin-like 3 isoform 2 [Homo sapiens] 138 3e-32
gi|119120874 formin-like 3 isoform 1 [Homo sapiens] 138 3e-32
gi|223278403 glutamate receptor, ionotropic, delta 2 (Grid2) int... 127 6e-29
gi|58331242 formin homology 2 domain containing 3 [Homo sapiens] 120 6e-27
gi|118572599 formin homology 2 domain containing 1 [Homo sapiens] 112 2e-24
gi|11386183 WAS protein family, member 2 [Homo sapiens] 105 3e-22
gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sap... 100 1e-20
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ... 96 2e-19
gi|153792074 proline rich 12 [Homo sapiens] 94 8e-19
gi|4507909 Wiskott-Aldrich syndrome protein [Homo sapiens] 92 3e-18
gi|210032580 SET domain containing 1B [Homo sapiens] 89 3e-17
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 88 4e-17
gi|23592228 extraembryonic, spermatogenesis, homeobox 1-like [Ho... 87 7e-17
gi|7706501 WW domain binding protein 11 [Homo sapiens] 87 7e-17
gi|150417989 cyclin K isoform 1 [Homo sapiens] 87 9e-17
>gi|157168329 formin 1 [Homo sapiens]
Length = 1196
Score = 2399 bits (6216), Expect = 0.0
Identities = 1196/1196 (100%), Positives = 1196/1196 (100%)
Query: 1 MENVDNSLDGSDVSEPAKPEAGLEVAQSILSKFSMKSLFGFTSKLESVNPEEEDAVLKAF 60
MENVDNSLDGSDVSEPAKPEAGLEVAQSILSKFSMKSLFGFTSKLESVNPEEEDAVLKAF
Sbjct: 1 MENVDNSLDGSDVSEPAKPEAGLEVAQSILSKFSMKSLFGFTSKLESVNPEEEDAVLKAF 60
Query: 61 HSLDVNPTSQQDDSSNGLDPQEAGSRVSPDLGNDEKIASVETESEGSQRKEAGTSLLAQE 120
HSLDVNPTSQQDDSSNGLDPQEAGSRVSPDLGNDEKIASVETESEGSQRKEAGTSLLAQE
Sbjct: 61 HSLDVNPTSQQDDSSNGLDPQEAGSRVSPDLGNDEKIASVETESEGSQRKEAGTSLLAQE 120
Query: 121 LLPLSTLKGTKDDVICVRGTLVHTTSDSDSDDGGQEPEEGSSTNGPKSPSGVLSEPSQES 180
LLPLSTLKGTKDDVICVRGTLVHTTSDSDSDDGGQEPEEGSSTNGPKSPSGVLSEPSQES
Sbjct: 121 LLPLSTLKGTKDDVICVRGTLVHTTSDSDSDDGGQEPEEGSSTNGPKSPSGVLSEPSQES 180
Query: 181 KENPGGFRENTVTGEMNGAELCAEDPQRIPPEMSSKLEAGNGGLQTERRPSQDQVGEEGS 240
KENPGGFRENTVTGEMNGAELCAEDPQRIPPEMSSKLEAGNGGLQTERRPSQDQVGEEGS
Sbjct: 181 KENPGGFRENTVTGEMNGAELCAEDPQRIPPEMSSKLEAGNGGLQTERRPSQDQVGEEGS 240
Query: 241 QDLPAVTNQNSSVGITESASSKKEVSGEKSFQLPAFFSGLRVLKKGATAEGGETITEIKP 300
QDLPAVTNQNSSVGITESASSKKEVSGEKSFQLPAFFSGLRVLKKGATAEGGETITEIKP
Sbjct: 241 QDLPAVTNQNSSVGITESASSKKEVSGEKSFQLPAFFSGLRVLKKGATAEGGETITEIKP 300
Query: 301 KDGDLALLKLTQPVQKSLVQAGLQTVKSEKKATDPKATPTLLEQLSLLLNIDMPKTEPKG 360
KDGDLALLKLTQPVQKSLVQAGLQTVKSEKKATDPKATPTLLEQLSLLLNIDMPKTEPKG
Sbjct: 301 KDGDLALLKLTQPVQKSLVQAGLQTVKSEKKATDPKATPTLLEQLSLLLNIDMPKTEPKG 360
Query: 361 ADPESPRREEMGCNADQESQSGPGVPQTQGGEVKPKSPETALEAFKALFIRPPRKGTTAD 420
ADPESPRREEMGCNADQESQSGPGVPQTQGGEVKPKSPETALEAFKALFIRPPRKGTTAD
Sbjct: 361 ADPESPRREEMGCNADQESQSGPGVPQTQGGEVKPKSPETALEAFKALFIRPPRKGTTAD 420
Query: 421 TSELEALKRKMRHEKESLRAVFERSNSKPADGPSDSKSPDHSLTEQDDRTPGRLQAVWPP 480
TSELEALKRKMRHEKESLRAVFERSNSKPADGPSDSKSPDHSLTEQDDRTPGRLQAVWPP
Sbjct: 421 TSELEALKRKMRHEKESLRAVFERSNSKPADGPSDSKSPDHSLTEQDDRTPGRLQAVWPP 480
Query: 481 PKTKDTEEKVGLKYTEAEYQAAILHLKREHKEEIENLQAQFELRAFHIRGEHAMITARLE 540
PKTKDTEEKVGLKYTEAEYQAAILHLKREHKEEIENLQAQFELRAFHIRGEHAMITARLE
Sbjct: 481 PKTKDTEEKVGLKYTEAEYQAAILHLKREHKEEIENLQAQFELRAFHIRGEHAMITARLE 540
Query: 541 ETIENLKHELEHRWRGGCEERKDVCISTDDDCPPKTFRNVCVQTDRETFLKPCESESKTT 600
ETIENLKHELEHRWRGGCEERKDVCISTDDDCPPKTFRNVCVQTDRETFLKPCESESKTT
Sbjct: 541 ETIENLKHELEHRWRGGCEERKDVCISTDDDCPPKTFRNVCVQTDRETFLKPCESESKTT 600
Query: 601 RSNQLVPKKLNISSLSQLSPPNDHKDIHAALQPMEGMASNQQKALPPPPASIPPPPPLPS 660
RSNQLVPKKLNISSLSQLSPPNDHKDIHAALQPMEGMASNQQKALPPPPASIPPPPPLPS
Sbjct: 601 RSNQLVPKKLNISSLSQLSPPNDHKDIHAALQPMEGMASNQQKALPPPPASIPPPPPLPS 660
Query: 661 GLGSLSPAPPMPPVSAGPPLPPPPPPPPPLPPPSSAGPPPPPPPPPLPNSPAPPNPGGPP 720
GLGSLSPAPPMPPVSAGPPLPPPPPPPPPLPPPSSAGPPPPPPPPPLPNSPAPPNPGGPP
Sbjct: 661 GLGSLSPAPPMPPVSAGPPLPPPPPPPPPLPPPSSAGPPPPPPPPPLPNSPAPPNPGGPP 720
Query: 721 PAPPPPGLAPPPPPGLFFGLGSSSSQCPRKPAIEPSCPMKPLYWTRIQISDRSQNATPTL 780
PAPPPPGLAPPPPPGLFFGLGSSSSQCPRKPAIEPSCPMKPLYWTRIQISDRSQNATPTL
Sbjct: 721 PAPPPPGLAPPPPPGLFFGLGSSSSQCPRKPAIEPSCPMKPLYWTRIQISDRSQNATPTL 780
Query: 781 WDSLEEPDIRDPSEFEYLFSKDTTQQKKKPLSETYEKKNKVKKIIKLLDGKRSQTVGILI 840
WDSLEEPDIRDPSEFEYLFSKDTTQQKKKPLSETYEKKNKVKKIIKLLDGKRSQTVGILI
Sbjct: 781 WDSLEEPDIRDPSEFEYLFSKDTTQQKKKPLSETYEKKNKVKKIIKLLDGKRSQTVGILI 840
Query: 841 SSLHLEMKDIQQAIFNVDDSVVDLETLAALYENRAQEDELVKIRKYYETSKEEELKLLDK 900
SSLHLEMKDIQQAIFNVDDSVVDLETLAALYENRAQEDELVKIRKYYETSKEEELKLLDK
Sbjct: 841 SSLHLEMKDIQQAIFNVDDSVVDLETLAALYENRAQEDELVKIRKYYETSKEEELKLLDK 900
Query: 901 PEQFLHELAQIPNFAERAQCIIFRSVFSEGITSLHRKVEIITRASKDLLHVKSVKDILAL 960
PEQFLHELAQIPNFAERAQCIIFRSVFSEGITSLHRKVEIITRASKDLLHVKSVKDILAL
Sbjct: 901 PEQFLHELAQIPNFAERAQCIIFRSVFSEGITSLHRKVEIITRASKDLLHVKSVKDILAL 960
Query: 961 ILAFGNYMNGGNRTRGQADGYSLEILPKLKDVKSRDNGINLVDYVVKYYLRYYDQEAGTE 1020
ILAFGNYMNGGNRTRGQADGYSLEILPKLKDVKSRDNGINLVDYVVKYYLRYYDQEAGTE
Sbjct: 961 ILAFGNYMNGGNRTRGQADGYSLEILPKLKDVKSRDNGINLVDYVVKYYLRYYDQEAGTE 1020
Query: 1021 KSVFPLPEPQDFFLASQVKFEDLIKDLRKLKRQLEASEKQMVVVCKESPKEYLQPFKDKL 1080
KSVFPLPEPQDFFLASQVKFEDLIKDLRKLKRQLEASEKQMVVVCKESPKEYLQPFKDKL
Sbjct: 1021 KSVFPLPEPQDFFLASQVKFEDLIKDLRKLKRQLEASEKQMVVVCKESPKEYLQPFKDKL 1080
Query: 1081 EEFFQKAKKEHKMEESHLENAQKSFETTVRYFGMKPKSGEKEITPSYVFMVWYEFCSDFK 1140
EEFFQKAKKEHKMEESHLENAQKSFETTVRYFGMKPKSGEKEITPSYVFMVWYEFCSDFK
Sbjct: 1081 EEFFQKAKKEHKMEESHLENAQKSFETTVRYFGMKPKSGEKEITPSYVFMVWYEFCSDFK 1140
Query: 1141 TIWKRESKNISKERLKMAQESVSKLTSEKKVETKKINPTASLKERLRQKEASVTTN 1196
TIWKRESKNISKERLKMAQESVSKLTSEKKVETKKINPTASLKERLRQKEASVTTN
Sbjct: 1141 TIWKRESKNISKERLKMAQESVSKLTSEKKVETKKINPTASLKERLRQKEASVTTN 1196
>gi|160707881 formin 2 [Homo sapiens]
Length = 1722
Score = 558 bits (1437), Expect = e-158
Identities = 304/609 (49%), Positives = 390/609 (64%), Gaps = 69/609 (11%)
Query: 645 LPPPP----ASIPPPPPLPSGLGSLSPAPPMPPVSAGPPLP------PPPPP------PP 688
+PPPP A IPPPPPLP + P PP+P V PP P PPPPP PP
Sbjct: 1118 IPPPPPLPGAGIPPPPPLPGA--GIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPP 1175
Query: 689 PLPPPSSAGPPPPP-------PPPPLPNS---PAPPNPG-GPPPAP----PPPGLAPPPP 733
P P P PPPPP PPPPLP + P PP PG G PPAP PPPG PPP
Sbjct: 1176 PPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGTGIPPP 1235
Query: 734 PGL--------------------------------FFGLGSSSSQCPRKPAIEPSCPMKP 761
P L FGLG + + RK IEP PMKP
Sbjct: 1236 PLLPVSGPPLLPQVGSSTLPTPQVCGFLPPPLPSGLFGLGMNQDKGSRKQPIEPCRPMKP 1295
Query: 762 LYWTRIQISDRSQNATPTLWDSLEEPDIRDPSEFEYLFSKDTTQQKKKPLSETYEKKNKV 821
LYWTRIQ+ + ++T +W+ +EEP I D EFE LFSK +++KKP+S+T K K
Sbjct: 1296 LYWTRIQLHSKRDSSTSLIWEKIEEPSI-DCHEFEELFSKTAVKERKKPISDTISK-TKA 1353
Query: 822 KKIIKLLDGKRSQTVGILISSLHLEMKDIQQAIFNVDDSVVDLETLAALYENRAQEDELV 881
K+++KLL KRSQ VGIL+SSLHL+MKDIQ A+ N+D+SVVDLETL ALYENRAQ DEL
Sbjct: 1354 KQVVKLLSNKRSQAVGILMSSLHLDMKDIQHAVVNLDNSVVDLETLQALYENRAQSDELE 1413
Query: 882 KIRKYYETSKEEE-LKLLDKPEQFLHELAQIPNFAERAQCIIFRSVFSEGITSLHRKVEI 940
KI K+ +SK++E K LDKPEQFL+EL+ IPNF+ER CI+F+S FSE I S+ RK+E+
Sbjct: 1414 KIEKHGRSSKDKENAKSLDKPEQFLYELSLIPNFSERVFCILFQSTFSESICSIRRKLEL 1473
Query: 941 ITRASKDLLHVKSVKDILALILAFGNYMNGGNRTRGQADGYSLEILPKLKDVKSRDNGIN 1000
+ + + L + V +L L+LAFGNYMNGGN+TRGQADG+ L+ILPKLKDVKS DN +
Sbjct: 1474 LQKLCETLKNGPGVMQVLGLVLAFGNYMNGGNKTRGQADGFGLDILPKLKDVKSSDNSRS 1533
Query: 1001 LVDYVVKYYLRYYDQEAGTEKSVFPLPEPQDFFLASQVKFEDLIKDLRKLKRQLEASEKQ 1060
L+ Y+V YYLR +D++AG E+ +FPLPEPQD F ASQ+KFED KDLRKLK+ L+A E +
Sbjct: 1534 LLSYIVSYYLRNFDEDAGKEQCLFPLPEPQDLFQASQMKFEDFQKDLRKLKKDLKACEVE 1593
Query: 1061 MVVVCKESPKEYLQPFKDKLEEFFQKAKKEHKMEESHLENAQKSFETTVRYFGMKPKSGE 1120
V + S KE++QPFK+ +E+F +AK + + EE+ L K F T YF MKPK GE
Sbjct: 1594 AGKVYQVSSKEHMQPFKENMEQFIIQAKIDQEAEENSLTETHKCFLETTAYFFMKPKLGE 1653
Query: 1121 KEITPSYVFMVWYEFCSDFKTIWKRESKNISKERLKMAQESVSKLTSEKKVETKKINPTA 1180
KE++P+ F +W+EF SDFK WK+E+K + +ER+K A+E V + K + K +
Sbjct: 1654 KEVSPNAFFSIWHEFSSDFKDFWKKENKLLLQERVKEAEE-VCRQKKGKSLYKIKPRHDS 1712
Query: 1181 SLKERLRQK 1189
+K ++ K
Sbjct: 1713 GIKAKISMK 1721
Score = 104 bits (259), Expect = 6e-22
Identities = 59/119 (49%), Positives = 65/119 (54%), Gaps = 29/119 (24%)
Query: 645 LPPPP----ASIPPPPPLPSGLGSLSPAPPMPPVSAGPPLP------PPPPP------PP 688
+PPPP A IPPPPPLP + P PP+P V PP P PPPPP PP
Sbjct: 1074 IPPPPPLPGAGIPPPPPLPG--AGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPP 1131
Query: 689 PLPPPSSAGPPPP-------PPPPPLPNS---PAPPNPG-GPPPAPPPPGLAPPPPPGL 736
P P P + PPPP PPPPPLP + P PP PG G PP PP PG+ PPPP L
Sbjct: 1132 PPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPL 1190
Score = 102 bits (253), Expect = 3e-21
Identities = 64/120 (53%), Positives = 66/120 (55%), Gaps = 30/120 (25%)
Query: 645 LPPPP-----ASIPPPPPLPSGLGSLSPAPPMPPVSAGPPLPPP----PPPPP------P 689
LPPPP A IPPPPPLP G G L P PP+P PP P P PPPPP P
Sbjct: 908 LPPPPPPLPGAGIPPPPPLP-GAGIL-PLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIP 965
Query: 690 LPPP-SSAGPPPP--------PPPPPLPNS---PAPPNPG-GPPPAPPPPGLAPPPPPGL 736
LPPP AG PPP PPPPPLP + P PP PG G PP PP PG PPPP L
Sbjct: 966 LPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1025
Score = 102 bits (253), Expect = 3e-21
Identities = 58/119 (48%), Positives = 63/119 (52%), Gaps = 29/119 (24%)
Query: 645 LPPPP----ASIPPPPPLPSGLGSLSPAPPMPPVSAGPPLP------PPPPP------PP 688
+PPPP A IPPPPPLP + P PP+P PP P PPPPP PP
Sbjct: 975 IPPPPPLPGAGIPPPPPLPG--AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP 1032
Query: 689 PLPPPSSAGPPPP-------PPPPPLPNS---PAPPNPG-GPPPAPPPPGLAPPPPPGL 736
P P P + PPPP PPPPPLP + P PP PG G PP PP PG PPPP L
Sbjct: 1033 PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1091
Score = 102 bits (253), Expect = 3e-21
Identities = 58/119 (48%), Positives = 63/119 (52%), Gaps = 29/119 (24%)
Query: 645 LPPPP----ASIPPPPPLPSGLGSLSPAPPMPPVSAGPPLP------PPPPP------PP 688
+PPPP A IPPPPPLP + P PP+P PP P PPPPP PP
Sbjct: 1008 IPPPPPLPGAGIPPPPPLPG--AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP 1065
Query: 689 PLPPPSSAGPPPP-------PPPPPLPNS---PAPPNPG-GPPPAPPPPGLAPPPPPGL 736
P P P + PPPP PPPPPLP + P PP PG G PP PP PG PPPP L
Sbjct: 1066 PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPL 1124
Score = 101 bits (252), Expect = 4e-21
Identities = 66/160 (41%), Positives = 78/160 (48%), Gaps = 20/160 (12%)
Query: 592 PCESESKTTRSNQLVPKKLNISSLSQLSPPNDHKDIHAALQPMEGMASNQQKALPP-PPA 650
P + T + +P+ + L PP A + P + LPP P A
Sbjct: 882 PLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLP-GAGIPPPPPLPGAGILPLPPLPGA 940
Query: 651 SIPPPPPLPSGLGSLSPAPPMPPVSAGPPLPPPPP----PPPPLPPPSSAGPPPP----- 701
IPPPPPLP ++ P PP+P AG PLPPP P PPPP P + PPPP
Sbjct: 941 GIPPPPPLPG--AAIPPPPPLP--GAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG 996
Query: 702 -PPPPPLPNS---PAPPNPG-GPPPAPPPPGLAPPPPPGL 736
PPPPPLP + P PP PG G PP PP PG PPPP L
Sbjct: 997 IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1036
Score = 101 bits (252), Expect = 4e-21
Identities = 58/119 (48%), Positives = 64/119 (53%), Gaps = 29/119 (24%)
Query: 645 LPPPP----ASIPPPPPLPSGLGSLSPAPPMPPVSAGPP-------LPPPPPPP----PP 689
+PPPP A IPPPPPLP + P PP+P PP +PPPPP P PP
Sbjct: 997 IPPPPPLPGAGIPPPPPLPGA--GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP 1054
Query: 690 LPPPSSAGPPPP--------PPPPPLPNS---PAPPNPG-GPPPAPPPPGLAPPPPPGL 736
PP AG PPP PPPPPLP + P PP PG G PP PP PG+ PPPP L
Sbjct: 1055 PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPL 1113
Score = 101 bits (251), Expect = 5e-21
Identities = 58/119 (48%), Positives = 62/119 (52%), Gaps = 29/119 (24%)
Query: 645 LPPPP----ASIPPPPPLPSGLGSLSPAPPMPPVSAGPPLP------PPPPP------PP 688
+PPPP A IPPPPPLP + P PP+P PP P PPPPP PP
Sbjct: 1063 IPPPPPLPGAGIPPPPPLPG--AGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPP 1120
Query: 689 PLPPPSSAGPPPP-------PPPPPLPN---SPAPPNPG-GPPPAPPPPGLAPPPPPGL 736
P P P + PPPP PPPPPLP P PP PG G PP PP PG PPPP L
Sbjct: 1121 PPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1179
Score = 100 bits (250), Expect = 6e-21
Identities = 58/119 (48%), Positives = 63/119 (52%), Gaps = 29/119 (24%)
Query: 645 LPPPP----ASIPPPPPLPSGLGSLSPAPPMPPVSAGPP-------LPPPPPPP----PP 689
+PPPP A IPPPPPLP + P PP+P PP +PPPPP P PP
Sbjct: 986 IPPPPPLPGAGIPPPPPLPGA--GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP 1043
Query: 690 LPPPSSAGPPPP--------PPPPPLPNS---PAPPNPG-GPPPAPPPPGLAPPPPPGL 736
PP AG PPP PPPPPLP + P PP PG G PP PP PG PPPP L
Sbjct: 1044 PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1102
Score = 100 bits (250), Expect = 6e-21
Identities = 58/119 (48%), Positives = 63/119 (52%), Gaps = 29/119 (24%)
Query: 645 LPPPP----ASIPPPPPLPSGLGSLSPAPPMPPVSAGPP-------LPPPPPPP----PP 689
+PPPP A IPPPPPLP + P PP+P PP +PPPPP P PP
Sbjct: 1030 IPPPPPLPGAGIPPPPPLPGA--GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP 1087
Query: 690 LPPPSSAGPPPP--------PPPPPLPNS---PAPPNPG-GPPPAPPPPGLAPPPPPGL 736
PP AG PPP PPPPPLP + P PP PG G PP PP PG PPPP L
Sbjct: 1088 PPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1146
Score = 100 bits (248), Expect = 1e-20
Identities = 60/118 (50%), Positives = 64/118 (54%), Gaps = 27/118 (22%)
Query: 645 LPPPP----ASIPPPPPLPSGLGSLSPAP------PMPPVSAGPPLPPPPPPP----PPL 690
+PPPP A+IPPPPPLP G G P P P PP G +PPPPP P PP
Sbjct: 942 IPPPPPLPGAAIPPPPPLP-GAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPP 1000
Query: 691 PPPSSAGPPPP--------PPPPPLPNS---PAPPNPG-GPPPAPPPPGLAPPPPPGL 736
PP AG PPP PPPPPLP + P PP PG G PP PP PG PPPP L
Sbjct: 1001 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1058
Score = 100 bits (248), Expect = 1e-20
Identities = 58/119 (48%), Positives = 62/119 (52%), Gaps = 29/119 (24%)
Query: 645 LPPPP----ASIPPPPPLPSGLGSLSPAPPMPPVSAGPP-------LPPPPPPP----PP 689
+PPPP A IPPPPPLP + P PP+P PP +PPPPP P PP
Sbjct: 1019 IPPPPPLPGAGIPPPPPLPGA--GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP 1076
Query: 690 LPPPSSAGPPPP--------PPPPPLPN---SPAPPNPG-GPPPAPPPPGLAPPPPPGL 736
PP AG PPP PPPPPLP P PP PG G PP PP PG PPPP L
Sbjct: 1077 PPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1135
Score = 99.0 bits (245), Expect = 2e-20
Identities = 56/119 (47%), Positives = 61/119 (51%), Gaps = 29/119 (24%)
Query: 645 LPPPP----ASIPPPPPLPSGLGSLSPAPPMPPVSAGPP-------LPPPPPPP----PP 689
+PPPP A IPPPPPLP + P PP+P PP +PPPPP P PP
Sbjct: 1052 IPPPPPLPGAGIPPPPPLPGA--GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPP 1109
Query: 690 LPPPSSAGPPPP--------PPPPPLPNSPAPPNPG----GPPPAPPPPGLAPPPPPGL 736
PP AG PPP PPPPPLP + PP P G PP PP PG PPPP L
Sbjct: 1110 PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPL 1168
Score = 98.6 bits (244), Expect = 3e-20
Identities = 58/120 (48%), Positives = 63/120 (52%), Gaps = 29/120 (24%)
Query: 644 ALPPPP----ASIPPPPPLPSGLGSLSPAPPMPPVSAGPP-------LPPPPPPP----P 688
A+PPPP A IP PPPLP + P PP+P PP +PPPPP P P
Sbjct: 952 AIPPPPPLPGAGIPLPPPLPGA--GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIP 1009
Query: 689 PLPPPSSAGPPPP--------PPPPPLPNS---PAPPNPG-GPPPAPPPPGLAPPPPPGL 736
P PP AG PPP PPPPPLP + P PP PG G PP PP PG PPPP L
Sbjct: 1010 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1069
Score = 96.3 bits (238), Expect = 2e-19
Identities = 100/368 (27%), Positives = 141/368 (38%), Gaps = 105/368 (28%)
Query: 459 PDHSLTEQDDRTPGRLQAVWPPPKTKDTEEKVGLKYTEAEYQAAILHLKREHKEEIENLQ 518
P HSL + + P R+ ++ PP K D E + L+ E E Q+A+ ++ + +
Sbjct: 607 PTHSLDYSEGQFPRRVPSMGPPSKPPDEEHR--LEDAETESQSAVSETPQKRSDAV---- 660
Query: 519 AQFELRAFHIRGEHAMITARLEETIENLKHELEHRWRGGCEERKDVCISTDDDCPPKTFR 578
Q E+ G+ A + +LE+TIE+L+ ++ ER+ + T+ +
Sbjct: 661 -QKEVVDMKSEGQ-ATVIQQLEQTIEDLRTKIAEL------ERQYPALDTEVASGHQGLE 712
Query: 579 NVCVQTDRETFLKPCESESKTTRSNQLVPKKLNISSLSQ-----LSPPNDH--------- 624
N V + L+ E K R ++++ K +S ++ PP D
Sbjct: 713 N-GVTASGDVCLEALRLEEKEVRHHRILEAKSIQTSPTEEGGVLTLPPVDGLPGRPPCPP 771
Query: 625 -----------KDIHAALQP------MEGMASNQQKALPPPPAS---------------- 651
+I + P ++ Q + PPPP S
Sbjct: 772 GAESGPQTKFCSEISLIVSPRRISVQLDSHQPTQSISQPPPPPSLLWSAGQGQPGSQPPH 831
Query: 652 -----------------------IPPPPPLP--------SGLGSLSPAPPMPPVSAGPPL 680
IP PPPLP GLG + P PP P P L
Sbjct: 832 SISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTESSSSMPGLGMVPPPPPPLPGMTVPTL 891
Query: 681 P----PPPPP-------PPPLPPPSSAGPPPPPPPPPLPNSPAPPNPG-GPPPAPPPPGL 728
P P PPP PPP PP AG PPPPP P P PP PG G PP PP PG
Sbjct: 892 PSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGA 951
Query: 729 APPPPPGL 736
A PPPP L
Sbjct: 952 AIPPPPPL 959
>gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]
Length = 1263
Score = 229 bits (585), Expect = 9e-60
Identities = 169/577 (29%), Positives = 276/577 (47%), Gaps = 77/577 (13%)
Query: 646 PPPP----ASIPPPPPLPSGLGSLSPA--------PPMPPVSAGPPLPPPPPP------- 686
PPPP A+IPPPPPLP G+G SP+ PP PP+ +PPPPPP
Sbjct: 632 PPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGI 691
Query: 687 -PPPLPPPSSAGPPPPPPP----PPLPNSPAPPNPGGPPPAPPPPGLAPPPPPGLFFGLG 741
PPP P P AG PPPPPP P +P P PP PGGP PPPPG+ PPPP FG+
Sbjct: 692 PPPPPPLPGEAGMPPPPPPLPGGPGIP--PPPPFPGGPGIPPPPPGMGMPPPPPFGFGVP 749
Query: 742 SSS----SQCPRKPAIEPSCPMKPLYWTRIQISDRSQNATPTLWDSLEEPDIRDPSEFEY 797
++ P+K +P ++ W+++ D SQ+ W ++E + F
Sbjct: 750 AAPVLPFGLTPKK-LYKPEVQLRRPNWSKLVAEDLSQDC---FWTKVKEDRFENNELFAK 805
Query: 798 L---FSKDTTQQKKKPLSETYEKKNKVK----KIIKLLDGKRSQTVGILISSLHLEMKDI 850
L FS T K K E E+K V+ K +K+LD K +Q + I + S + ++I
Sbjct: 806 LTLTFSAQTKTSKAKKDQEGGEEKKSVQKKKVKELKVLDSKTAQNLSIFLGSFRMPYQEI 865
Query: 851 QQAIFNVDDSVVDLETLAALYENRAQEDELVKIRKYYETSKEEELKLLDKPEQFLHELAQ 910
+ I V+++V+ + L + + ++L + + ++E L + EQF +
Sbjct: 866 KNVILEVNEAVLTESMIQNLIKQMPEPEQLKML-----SELKDEYDDLAESEQFGVVMGT 920
Query: 911 IPNFAERAQCIIFRSVFSEGITSLHRKVEIITRASKDLLHVKSVKDILALILAFGNYMNG 970
+P R I+F+ FSE + ++ ++ +T A ++L +S ++L + L GNYMN
Sbjct: 921 VPRLRPRLNAILFKLQFSEQVENIKPEIVSVTAACEELRKSESFSNLLEITLLVGNYMNA 980
Query: 971 GNRTRGQADGYSLEILPKLKDVKSRDNGINLVDYVVKY-------YLRYYDQEAGTEKSV 1023
G+R G A G+++ L KL+D KS D + L+ ++ + L++ D+ A EK
Sbjct: 981 GSRNAG-AFGFNISFLCKLRDTKSTDQKMTLLHFLAELCENDYPDVLKFPDELAHVEK-- 1037
Query: 1024 FPLPEPQDFFLASQVKFEDLIKDLRKLKRQLEASEKQMVVVCKESPKEYLQPFKDKLEEF 1083
AS+V E+L K+L ++K+Q+ E+ V + + F +K+ F
Sbjct: 1038 -----------ASRVSAENLQKNLDQMKKQISDVERD--VQNFPAATDEKDKFVEKMTSF 1084
Query: 1084 FQKAKKEHKMEESHLENAQKSFETTVRYFGMKPKSGEKEITPSYVFMVWYEFCSDF---- 1139
+ A++++ N + ++ YF P K+++ FM + F + F
Sbjct: 1085 VKDAQEQYNKLRMMHSNMETLYKELGEYFLFDP----KKLSVEEFFMDLHNFRNMFLQAV 1140
Query: 1140 KTIWKRESKNISKERLKMAQESVSKLTSEKKVETKKI 1176
K KR R K+A+E K EK+ + +++
Sbjct: 1141 KENQKRRETEEKMRRAKLAKEKAEKERLEKQQKREQL 1177
Score = 50.1 bits (118), Expect = 1e-05
Identities = 32/76 (42%), Positives = 33/76 (43%), Gaps = 11/76 (14%)
Query: 692 PPSSAGPPPPPPPPPLPNS-----PAPPNPGGPPPAPPPPGLAPPPPPGLFFGLG---SS 743
PPS P PP PPLP P PP PG PPPP PPPPP G SS
Sbjct: 564 PPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPP---PPPPPPPPLPGGVCISS 620
Query: 744 SSQCPRKPAIEPSCPM 759
P AI P P+
Sbjct: 621 PPSLPGGTAISPPPPL 636
>gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]
Length = 1272
Score = 229 bits (585), Expect = 9e-60
Identities = 169/577 (29%), Positives = 276/577 (47%), Gaps = 77/577 (13%)
Query: 646 PPPP----ASIPPPPPLPSGLGSLSPA--------PPMPPVSAGPPLPPPPPP------- 686
PPPP A+IPPPPPLP G+G SP+ PP PP+ +PPPPPP
Sbjct: 641 PPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGI 700
Query: 687 -PPPLPPPSSAGPPPPPPP----PPLPNSPAPPNPGGPPPAPPPPGLAPPPPPGLFFGLG 741
PPP P P AG PPPPPP P +P P PP PGGP PPPPG+ PPPP FG+
Sbjct: 701 PPPPPPLPGEAGMPPPPPPLPGGPGIP--PPPPFPGGPGIPPPPPGMGMPPPPPFGFGVP 758
Query: 742 SSS----SQCPRKPAIEPSCPMKPLYWTRIQISDRSQNATPTLWDSLEEPDIRDPSEFEY 797
++ P+K +P ++ W+++ D SQ+ W ++E + F
Sbjct: 759 AAPVLPFGLTPKK-LYKPEVQLRRPNWSKLVAEDLSQDC---FWTKVKEDRFENNELFAK 814
Query: 798 L---FSKDTTQQKKKPLSETYEKKNKVK----KIIKLLDGKRSQTVGILISSLHLEMKDI 850
L FS T K K E E+K V+ K +K+LD K +Q + I + S + ++I
Sbjct: 815 LTLTFSAQTKTSKAKKDQEGGEEKKSVQKKKVKELKVLDSKTAQNLSIFLGSFRMPYQEI 874
Query: 851 QQAIFNVDDSVVDLETLAALYENRAQEDELVKIRKYYETSKEEELKLLDKPEQFLHELAQ 910
+ I V+++V+ + L + + ++L + + ++E L + EQF +
Sbjct: 875 KNVILEVNEAVLTESMIQNLIKQMPEPEQLKML-----SELKDEYDDLAESEQFGVVMGT 929
Query: 911 IPNFAERAQCIIFRSVFSEGITSLHRKVEIITRASKDLLHVKSVKDILALILAFGNYMNG 970
+P R I+F+ FSE + ++ ++ +T A ++L +S ++L + L GNYMN
Sbjct: 930 VPRLRPRLNAILFKLQFSEQVENIKPEIVSVTAACEELRKSESFSNLLEITLLVGNYMNA 989
Query: 971 GNRTRGQADGYSLEILPKLKDVKSRDNGINLVDYVVKY-------YLRYYDQEAGTEKSV 1023
G+R G A G+++ L KL+D KS D + L+ ++ + L++ D+ A EK
Sbjct: 990 GSRNAG-AFGFNISFLCKLRDTKSTDQKMTLLHFLAELCENDYPDVLKFPDELAHVEK-- 1046
Query: 1024 FPLPEPQDFFLASQVKFEDLIKDLRKLKRQLEASEKQMVVVCKESPKEYLQPFKDKLEEF 1083
AS+V E+L K+L ++K+Q+ E+ V + + F +K+ F
Sbjct: 1047 -----------ASRVSAENLQKNLDQMKKQISDVERD--VQNFPAATDEKDKFVEKMTSF 1093
Query: 1084 FQKAKKEHKMEESHLENAQKSFETTVRYFGMKPKSGEKEITPSYVFMVWYEFCSDF---- 1139
+ A++++ N + ++ YF P K+++ FM + F + F
Sbjct: 1094 VKDAQEQYNKLRMMHSNMETLYKELGEYFLFDP----KKLSVEEFFMDLHNFRNMFLQAV 1149
Query: 1140 KTIWKRESKNISKERLKMAQESVSKLTSEKKVETKKI 1176
K KR R K+A+E K EK+ + +++
Sbjct: 1150 KENQKRRETEEKMRRAKLAKEKAEKERLEKQQKREQL 1186
Score = 50.1 bits (118), Expect = 1e-05
Identities = 32/76 (42%), Positives = 33/76 (43%), Gaps = 11/76 (14%)
Query: 692 PPSSAGPPPPPPPPPLPNS-----PAPPNPGGPPPAPPPPGLAPPPPPGLFFGLG---SS 743
PPS P PP PPLP P PP PG PPPP PPPPP G SS
Sbjct: 573 PPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPP---PPPPPPPPLPGGVCISS 629
Query: 744 SSQCPRKPAIEPSCPM 759
P AI P P+
Sbjct: 630 PPSLPGGTAISPPPPL 645
>gi|32880208 diaphanous homolog 3 isoform b [Homo sapiens]
Length = 849
Score = 200 bits (509), Expect = 6e-51
Identities = 159/584 (27%), Positives = 264/584 (45%), Gaps = 77/584 (13%)
Query: 623 DHKDIHAALQPMEGMASNQQKALP---------PPPASIPPPPPLPSGLGSLSPAPPMPP 673
DH++ A LQ E + Q L P +IP PP G G S PP PP
Sbjct: 259 DHQETQAELQKKEAKINELQAELQAFKSQFGALPADCNIPLPPSKEGGTGH-SALPPPPP 317
Query: 674 VSAGPPLPPPPPPPPPLPPPSSAGPPPPPPPPPLPNSPAPPNPGGPPPAPPPPGLA---- 729
+ +G +PPPPPP PPPPPLP P + GP P PPP G
Sbjct: 318 LPSGGGVPPPPPP---------------PPPPPLPGMRMPFS--GPVPPPPPLGFLGGQN 360
Query: 730 PPPPPGLFFGLGSSSSQCPRKPAIEPSCPMKPLYWTRIQISDRSQNATPTLWDSLEEPDI 789
PP P L FGL K +P M+ L W +I+ + ++N W + E
Sbjct: 361 SPPLPILPFGL-------KPKKEFKPEISMRRLNWLKIRPHEMTENC---FWIKVNENKY 410
Query: 790 RDPSEFEYLFSKDTTQQKKKPLSETYEKKNKVKKII---KLLDGKRSQTVGILISSLHLE 846
+ L + QQK++ E E+K +KK I K LD K +Q + I +SS +
Sbjct: 411 ENVDLLCKLENTFCCQQKERREEEDIEEKKSIKKKIKELKFLDSKIAQNLSIFLSSFRVP 470
Query: 847 MKDIQQAIFNVDDSVVDLETLAALYENRAQEDELVKIRKYYETSKEEELKLLDKPEQFLH 906
++I+ I VD++ + + L ++ +++L + ++ + E L +PEQF+
Sbjct: 471 YEEIRMMILEVDETRLAESMIQNLIKHLPDQEQLNSLSQF-----KSEYSNLCEPEQFVV 525
Query: 907 ELAQIPNFAERAQCIIFRSVFSEGITSLHRKVEIITRASKDLLHVKSVKDILALILAFGN 966
++ + R I+F+ F E + ++ + ++ A +++ KS +L L+L GN
Sbjct: 526 VMSNVKRLRPRLSAILFKLQFEEQVNNIKPDIMAVSTACEEIKKSKSFSKLLELVLLMGN 585
Query: 967 YMNGGNRTRGQADGYSLEILPKLKDVKSRDNGINLVDYVVKYYLRYYDQEAGTEKSVFPL 1026
YMN G+R Q G++L L KLKD KS D L+ ++V+ Y + PL
Sbjct: 586 YMNAGSR-NAQTFGFNLSSLCKLKDTKSADQKTTLLHFLVEICEEKYPDILNFVDDLEPL 644
Query: 1027 PEPQDFFLASQVKFEDLIKDLRKLKRQLEASEKQMVVVCKESPKEYLQPFKDKLEEFFQK 1086
+ AS+V E L K+LR++ RQL+ EK++ P++ F K+ F
Sbjct: 645 DK------ASKVSVETLEKNLRQMGRQLQQLEKELETF--PPPEDLHDKFVTKMSRFVIS 696
Query: 1087 AKKEHKMEESHLENAQKSFETTVRYFGMKPKSGEKEITPSYVFMVWYEFCSDFKTIWKRE 1146
AK++++ EN +K +++ + Y+ + K E DF T +
Sbjct: 697 AKEQYETLSKLHENMEKLYQSIIGYYAIDVKKVSVE---------------DFLT----D 737
Query: 1147 SKNISKERLKMAQESVSKLTSEKKVETKKINPTASLKERLRQKE 1190
N ++ +E++ K +E+K + +I + +ERL +++
Sbjct: 738 LNNFRTTFMQAIKENIKKREAEEKEKRVRIAKELAERERLERQQ 781
>gi|110225351 diaphanous homolog 3 isoform a [Homo sapiens]
Length = 1193
Score = 200 bits (509), Expect = 6e-51
Identities = 159/584 (27%), Positives = 264/584 (45%), Gaps = 77/584 (13%)
Query: 623 DHKDIHAALQPMEGMASNQQKALP---------PPPASIPPPPPLPSGLGSLSPAPPMPP 673
DH++ A LQ E + Q L P +IP PP G G S PP PP
Sbjct: 522 DHQETQAELQKKEAKINELQAELQAFKSQFGALPADCNIPLPPSKEGGTGH-SALPPPPP 580
Query: 674 VSAGPPLPPPPPPPPPLPPPSSAGPPPPPPPPPLPNSPAPPNPGGPPPAPPPPGLA---- 729
+ +G +PPPPPP PPPPPLP P + GP P PPP G
Sbjct: 581 LPSGGGVPPPPPP---------------PPPPPLPGMRMPFS--GPVPPPPPLGFLGGQN 623
Query: 730 PPPPPGLFFGLGSSSSQCPRKPAIEPSCPMKPLYWTRIQISDRSQNATPTLWDSLEEPDI 789
PP P L FGL K +P M+ L W +I+ + ++N W + E
Sbjct: 624 SPPLPILPFGL-------KPKKEFKPEISMRRLNWLKIRPHEMTENC---FWIKVNENKY 673
Query: 790 RDPSEFEYLFSKDTTQQKKKPLSETYEKKNKVKKII---KLLDGKRSQTVGILISSLHLE 846
+ L + QQK++ E E+K +KK I K LD K +Q + I +SS +
Sbjct: 674 ENVDLLCKLENTFCCQQKERREEEDIEEKKSIKKKIKELKFLDSKIAQNLSIFLSSFRVP 733
Query: 847 MKDIQQAIFNVDDSVVDLETLAALYENRAQEDELVKIRKYYETSKEEELKLLDKPEQFLH 906
++I+ I VD++ + + L ++ +++L + ++ + E L +PEQF+
Sbjct: 734 YEEIRMMILEVDETRLAESMIQNLIKHLPDQEQLNSLSQF-----KSEYSNLCEPEQFVV 788
Query: 907 ELAQIPNFAERAQCIIFRSVFSEGITSLHRKVEIITRASKDLLHVKSVKDILALILAFGN 966
++ + R I+F+ F E + ++ + ++ A +++ KS +L L+L GN
Sbjct: 789 VMSNVKRLRPRLSAILFKLQFEEQVNNIKPDIMAVSTACEEIKKSKSFSKLLELVLLMGN 848
Query: 967 YMNGGNRTRGQADGYSLEILPKLKDVKSRDNGINLVDYVVKYYLRYYDQEAGTEKSVFPL 1026
YMN G+R Q G++L L KLKD KS D L+ ++V+ Y + PL
Sbjct: 849 YMNAGSR-NAQTFGFNLSSLCKLKDTKSADQKTTLLHFLVEICEEKYPDILNFVDDLEPL 907
Query: 1027 PEPQDFFLASQVKFEDLIKDLRKLKRQLEASEKQMVVVCKESPKEYLQPFKDKLEEFFQK 1086
+ AS+V E L K+LR++ RQL+ EK++ P++ F K+ F
Sbjct: 908 DK------ASKVSVETLEKNLRQMGRQLQQLEKELETF--PPPEDLHDKFVTKMSRFVIS 959
Query: 1087 AKKEHKMEESHLENAQKSFETTVRYFGMKPKSGEKEITPSYVFMVWYEFCSDFKTIWKRE 1146
AK++++ EN +K +++ + Y+ + K E DF T +
Sbjct: 960 AKEQYETLSKLHENMEKLYQSIIGYYAIDVKKVSVE---------------DFLT----D 1000
Query: 1147 SKNISKERLKMAQESVSKLTSEKKVETKKINPTASLKERLRQKE 1190
N ++ +E++ K +E+K + +I + +ERL +++
Sbjct: 1001 LNNFRTTFMQAIKENIKKREAEEKEKRVRIAKELAERERLERQQ 1044
>gi|21071077 dishevelled-associated activator of morphogenesis 1 [Homo
sapiens]
Length = 1078
Score = 192 bits (487), Expect = 2e-48
Identities = 151/547 (27%), Positives = 255/547 (46%), Gaps = 66/547 (12%)
Query: 658 LPSGLGSLSPAPPMPPVSAGPPLPPPPPPPPPLPPPSSAGPPPPPPPPPLPNSPAPPNPG 717
+P G +P P P G LPPPPPPP P G PPPPPPLP PG
Sbjct: 527 IPGGPSPGAPGGPFPSSVPGSLLPPPPPPPLP-------GGMLPPPPPPLP-------PG 572
Query: 718 GPPPAPPPPGL-APPPPPGLFFGLGSSSSQCPRKPAIEPSCPMKPLYWTRIQISDRSQNA 776
GPPP P PP L A PPPG GL P +P+ +K W+++
Sbjct: 573 GPPPPPGPPPLGAIMPPPGAPMGLALKKKSIP-----QPTNALKSFNWSKLP----ENKL 623
Query: 777 TPTLWDSLEEPD---IRDPSEFEYLFS-----------KDTTQQKKKPLSETYEKKNKVK 822
T+W +++ I D + E FS ++ Q++ + +T K KVK
Sbjct: 624 EGTVWTEIDDTKVFKILDLEDLERTFSAYQRQQDFFVNSNSKQKEADAIDDTLSSKLKVK 683
Query: 823 KIIKLLDGKRSQTVGILISSLHLEMKDIQQAIFNVDDSV-VDLETLAALYENRAQEDELV 881
++ ++DG+R+Q IL+S L L +I++AI +D+ + + L L + ++ ++
Sbjct: 684 EL-SVIDGRRAQNCNILLSRLKLSNDEIKRAILTMDEQEDLPKDMLEQLLKFVPEKSDID 742
Query: 882 KIRKYYETSKEEELKLLDKPEQFLHELAQIPNFAERAQCIIFRSVFSEGITSLHRKVEII 941
+ ++ + EL + K ++FL E+++I ++ +R Q + F+ F+E + + KVE I
Sbjct: 743 LLEEH-----KHELDRMAKADRFLFEMSRINHYQQRLQSLYFKKKFAERVAEVKPKVEAI 797
Query: 942 TRASKDLLHVKSVKDILALILAFGNYMNGGNRTRGQADGYSLEILPKLKDVKSR-DNGIN 1000
S+++ ++K +L ++LAFGNYMN G RG A G+ + L K+ D KS D I
Sbjct: 798 RSGSEEVFRSGALKQLLEVVLAFGNYMNKGQ--RGNAYGFKISSLNKIADTKSSIDKNIT 855
Query: 1001 LVDYVVKYYLRYYDQEAGTEKSVFPLPEPQDFFLASQVKFEDLIKDLRKLKRQLEASEKQ 1060
L+ Y++ Y + + +P+ A++V +L K++ L+ L+A E +
Sbjct: 856 LLHYLITIVENKYPSVLNLNEELRDIPQ------AAKVNMTELDKEISTLRSGLKAVETE 909
Query: 1061 MVVVCKESPKEYLQPFKDKLEEFFQKAKKEHKMEESHLENAQKSFETTVRYFGMKPKSGE 1120
+ K P + F + +F A E L A+ F V++FG +
Sbjct: 910 LEYQ-KSQPPQPGDKFVSVVSQFITVASFSFSDVEDLLAEAKDLFTKAVKHFGEE----A 964
Query: 1121 KEITPSYVFMVWYEFCSDFKTIWKRESKNISKE------RLKMAQESVSKLTSEKKVETK 1174
+I P F ++ +F K+E++N+ K+ R +M + + E+K+
Sbjct: 965 GKIQPDEFFGIFDQFLQAVSEA-KQENENMRKKKEEEERRARMEAQLKEQRERERKMRKA 1023
Query: 1175 KINPTAS 1181
K N S
Sbjct: 1024 KENSEES 1030
>gi|33356148 formin-like 1 [Homo sapiens]
Length = 1100
Score = 189 bits (479), Expect = 2e-47
Identities = 162/521 (31%), Positives = 237/521 (45%), Gaps = 60/521 (11%)
Query: 644 ALPPPPASIPPPPPLPSGLGSLSPAPPMPPVSAGPPLP--PPPPPPPPLP---PPSSAGP 698
A P P A+ PPPPPLP GL S APP P A PPLP P PPP PPLP PP P
Sbjct: 534 AEPAPGAAPPPPPPLP-GLPSPQEAPPSAPPQA-PPLPGSPEPPPAPPLPGDLPP----P 587
Query: 699 PPPPPPPPLPNSPAPPNPGGPPPAPPPPGLAPPPPPGLFFGLGSSSSQCPRKPAIEPSCP 758
PPPPPPPP + P PP PPP PPPPG PP L K I+
Sbjct: 588 PPPPPPPPGTDGPVPP---PPPPPPPPPG---GPPDALGRRDSELGPGVKAKKPIQTKFR 641
Query: 759 MKPLYWTRIQISDRSQNATPTLWDSLEEPDI---RDPSEFEYLFSKDTTQQKKKPLSETY 815
M L W ++ S T T++ L + + D S+FE F K +Q LS
Sbjct: 642 MPLLNWVALKPS----QITGTVFTELNDEKVLQELDMSDFEEQF-KTKSQGPSLDLSALK 696
Query: 816 EK-KNKVKKIIKLLDGKRSQTVGILISSLHLEMKDIQQAIFNVDDSVVDLETLAALYENR 874
K K L++ R++ + I + +L + I QAI D + L+ L L
Sbjct: 697 SKAAQKAPSKATLIEANRAKNLAITLRKGNLGAERICQAIEAYDLQALGLDFLELLMRFL 756
Query: 875 AQEDELVKIRKYYETSKEEELKLLDKPEQFLHELAQIPNFAERAQCIIFRSVFSEGITSL 934
E E I ++ ++ ++ L + ++F+ ++IP ER + F F + L
Sbjct: 757 PTEYERSLITRF--EREQRPMEELSEEDRFMLCFSRIPRLPERMTTLTFLGNFPDTAQLL 814
Query: 935 HRKVEIITRASKDLLHVKSVKDILALILAFGNYMNGGNRTRGQADGYSLEILPKLKDVKS 994
++ I AS + ++ IL ++LAFGNYMN RG A G+ L+ L L ++KS
Sbjct: 815 MPQLNAIIAASMSIKSSDKLRQILEIVLAFGNYMNSSK--RGAAYGFRLQSLDALLEMKS 872
Query: 995 RDNGINLVDYVVKYYLRYYDQEAGTEKSVFPLPEPQDFFLASQVKFEDLIKDLRKLKRQL 1054
D L+ Y+VK Y Q G + L + A V + ++ D+R L+R L
Sbjct: 873 TDRKQTLLHYLVKVIAEKYPQLTGFHSDLHFLDK------AGSVSLDSVLADVRSLQRGL 926
Query: 1055 EASEKQMVVV--CKESPKEYLQPFKDKLEEFFQKAKKEHKMEESHLENAQKSFETTVRYF 1112
E ++++ V C KE+L+ +++ +K AQ++FE+ V YF
Sbjct: 927 ELTQREFVRQDDCMVL-KEFLRANSPTMDKLLADSK-----------TAQEAFESVVEYF 974
Query: 1113 GMKPKSGEKEITPSYVFMVWYEFCSDFKTI------WKRES 1147
G PK+ +P F ++ F +K WK+E+
Sbjct: 975 GENPKT----TSPGLFFSLFSRFIKAYKKAEQEVEQWKKEA 1011
>gi|6382071 diaphanous 2 isoform 12C [Homo sapiens]
Length = 1096
Score = 187 bits (476), Expect = 4e-47
Identities = 154/570 (27%), Positives = 261/570 (45%), Gaps = 82/570 (14%)
Query: 625 KDIHAALQPMEGMAS--NQQKALPPPPASIPPPPPLPSGLGSLSPAPPMPPVSAGPPLPP 682
K++ A +Q + A + +P PPA APP+P V GPP PP
Sbjct: 526 KELEAEIQQLRTQAQVLSSSSGIPGPPA-----------------APPLPGV--GPP-PP 565
Query: 683 PPPPPPPLPPPSSAGPPPPPPPPPLPNS---PAPPNP----GGPPPAPPPPGLAPPPPPG 735
PP PP P G P PPPPPPLP P PP P GGPPP PP G+ PPPPG
Sbjct: 566 PPAPPLP------GGAPLPPPPPPLPGMMGIPPPPPPPLLFGGPPPPPPLGGV--PPPPG 617
Query: 736 LFFGLGSSSSQCPRKPAIEPSCPMKPLYWTRIQISDRSQNATPTLWDSLEEPDIRDPSEF 795
+ L Q K +P MK + W++I+ ++ S+N W ++E +P F
Sbjct: 618 ISLNLPYGMKQ---KKMYKPEVSMKRINWSKIEPTELSENC---FWLRVKEDKFENPDLF 671
Query: 796 EYLFSKDTTQQKKKPLSETYEKK-----NKVKKIIKLLDGKRSQTVGILISSLHLEMKDI 850
L TQ K + +E E+K K K +++LD K +Q + I + S + +DI
Sbjct: 672 AKLALNFATQIKVQKNAEALEEKKTGPTKKKVKELRILDPKTAQNLSIFLGSYRMPYEDI 731
Query: 851 QQAIFNVDDSVVDLETLAALYENRAQE---DELVKIRKYYETSKEEELKLLDKPEQFLHE 907
+ I V++ ++ + L ++ ++ +EL +++ Y+ L +PEQF
Sbjct: 732 RNVILEVNEDMLSEALIQNLVKHLPEQKILNELAELKNEYDD--------LCEPEQFGVV 783
Query: 908 LAQIPNFAERAQCIIFRSVFSEGITSLHRKVEIITRASKDLLHVKSVKDILALILAFGNY 967
++ + R I+F+ F E I ++ + +T A ++L +S +L L+L GNY
Sbjct: 784 MSSVKMLQPRLSSILFKLTFEEHINNIKPSIIAVTLACEELKKSESFNRLLELVLLVGNY 843
Query: 968 MNGGNRTRGQADGYSLEILPKLKDVKSRDNGINLVDYVVKYYLRYYDQEAGTEKSVFPLP 1027
MN G+R Q+ G+ + L K++D KS D L+ ++ Y + + P
Sbjct: 844 MNSGSR-NAQSLGFKINFLCKIRDTKSADQKTTLLHFIADICEEKY-------RDILKFP 895
Query: 1028 EPQDFF-LASQVKFEDLIKDLRKLKRQLEASEKQMVVVCKESPKEYLQ--PFKDKLEEFF 1084
E + AS+V + L +L +++Q+ E+ + K+ P+ Q F +K+ F
Sbjct: 896 EELEHVESASKVSAQILKSNLASMEQQIVHLERDI----KKFPQAENQHDKFVEKMTSFT 951
Query: 1085 QKAKKEHKMEESHLENAQKSFETTVRYFGMKPKSGEKEITPSYVFMVWYEFCSDFKTIWK 1144
+ A+++++ + N K +E YF K+ E ++ ++F+T++
Sbjct: 952 KTAREQYEKLSTMHNNMMKLYENLGEYFIFDSKTVSIE--------EFFGDLNNFRTLFL 1003
Query: 1145 RESKNISKERLKMAQESVSKLTSEKKVETK 1174
+ +K R + +KL EK + K
Sbjct: 1004 EAVRENNKRREMEEKTRRAKLAKEKAEQEK 1033
>gi|5803003 diaphanous 2 isoform 156 [Homo sapiens]
Length = 1101
Score = 187 bits (476), Expect = 4e-47
Identities = 154/570 (27%), Positives = 261/570 (45%), Gaps = 82/570 (14%)
Query: 625 KDIHAALQPMEGMAS--NQQKALPPPPASIPPPPPLPSGLGSLSPAPPMPPVSAGPPLPP 682
K++ A +Q + A + +P PPA APP+P V GPP PP
Sbjct: 526 KELEAEIQQLRTQAQVLSSSSGIPGPPA-----------------APPLPGV--GPP-PP 565
Query: 683 PPPPPPPLPPPSSAGPPPPPPPPPLPNS---PAPPNP----GGPPPAPPPPGLAPPPPPG 735
PP PP P G P PPPPPPLP P PP P GGPPP PP G+ PPPPG
Sbjct: 566 PPAPPLP------GGAPLPPPPPPLPGMMGIPPPPPPPLLFGGPPPPPPLGGV--PPPPG 617
Query: 736 LFFGLGSSSSQCPRKPAIEPSCPMKPLYWTRIQISDRSQNATPTLWDSLEEPDIRDPSEF 795
+ L Q K +P MK + W++I+ ++ S+N W ++E +P F
Sbjct: 618 ISLNLPYGMKQ---KKMYKPEVSMKRINWSKIEPTELSENC---FWLRVKEDKFENPDLF 671
Query: 796 EYLFSKDTTQQKKKPLSETYEKK-----NKVKKIIKLLDGKRSQTVGILISSLHLEMKDI 850
L TQ K + +E E+K K K +++LD K +Q + I + S + +DI
Sbjct: 672 AKLALNFATQIKVQKNAEALEEKKTGPTKKKVKELRILDPKTAQNLSIFLGSYRMPYEDI 731
Query: 851 QQAIFNVDDSVVDLETLAALYENRAQE---DELVKIRKYYETSKEEELKLLDKPEQFLHE 907
+ I V++ ++ + L ++ ++ +EL +++ Y+ L +PEQF
Sbjct: 732 RNVILEVNEDMLSEALIQNLVKHLPEQKILNELAELKNEYDD--------LCEPEQFGVV 783
Query: 908 LAQIPNFAERAQCIIFRSVFSEGITSLHRKVEIITRASKDLLHVKSVKDILALILAFGNY 967
++ + R I+F+ F E I ++ + +T A ++L +S +L L+L GNY
Sbjct: 784 MSSVKMLQPRLSSILFKLTFEEHINNIKPSIIAVTLACEELKKSESFNRLLELVLLVGNY 843
Query: 968 MNGGNRTRGQADGYSLEILPKLKDVKSRDNGINLVDYVVKYYLRYYDQEAGTEKSVFPLP 1027
MN G+R Q+ G+ + L K++D KS D L+ ++ Y + + P
Sbjct: 844 MNSGSR-NAQSLGFKINFLCKIRDTKSADQKTTLLHFIADICEEKY-------RDILKFP 895
Query: 1028 EPQDFF-LASQVKFEDLIKDLRKLKRQLEASEKQMVVVCKESPKEYLQ--PFKDKLEEFF 1084
E + AS+V + L +L +++Q+ E+ + K+ P+ Q F +K+ F
Sbjct: 896 EELEHVESASKVSAQILKSNLASMEQQIVHLERDI----KKFPQAENQHDKFVEKMTSFT 951
Query: 1085 QKAKKEHKMEESHLENAQKSFETTVRYFGMKPKSGEKEITPSYVFMVWYEFCSDFKTIWK 1144
+ A+++++ + N K +E YF K+ E ++ ++F+T++
Sbjct: 952 KTAREQYEKLSTMHNNMMKLYENLGEYFIFDSKTVSIE--------EFFGDLNNFRTLFL 1003
Query: 1145 RESKNISKERLKMAQESVSKLTSEKKVETK 1174
+ +K R + +KL EK + K
Sbjct: 1004 EAVRENNKRREMEEKTRRAKLAKEKAEQEK 1033
>gi|40548415 dishevelled associated activator of morphogenesis 2 [Homo
sapiens]
Length = 1067
Score = 184 bits (466), Expect = 6e-46
Identities = 150/556 (26%), Positives = 257/556 (46%), Gaps = 70/556 (12%)
Query: 641 QQKALPPPPASIPPPPPLPSGLGSLSPAPPMPPVSAGPPLPPPPPPPPPLPPPSSAGPPP 700
Q L P S PPPP P L S +PP PPPPLP P
Sbjct: 510 QLSELSTGPVSSPPPPGGPLTLSSSMTTNDLPP------------PPPPLPFACC----P 553
Query: 701 PPPPPPLPNSPAPPNPGGPPPAPPPPGLAPPPPPGLFFGLGSSSSQCPRKPAIEPSCPMK 760
PPPPPPLP P P PP APP G+ P P + SS +K +PS P+K
Sbjct: 554 PPPPPPLP----PGGPPTPPGAPPCLGMGLPLPQDPY---PSSDVPLRKKRVPQPSHPLK 606
Query: 761 PLYWTRIQISDRSQNATPTLWDSLEEPD---IRDPSEFEYLFSKDTTQQKKKPLSETYEK 817
W ++ + T+W+ +++ I D +FE +FS QK+ +E
Sbjct: 607 SFNWVKLN----EERVPGTVWNEIDDMQVFRILDLEDFEKMFSAYQRHQKELGSTEDIYL 662
Query: 818 KNKVKKIIKLLDGKRSQTVGILISSLHLEMKDIQQAIFNVDDSVVDL--ETLAALYENRA 875
++ K + ++DG+R+Q IL+S L L ++I+QAI +D+ DL + L L +
Sbjct: 663 ASRKVKELSVIDGRRAQNCIILLSKLKLSNEEIRQAILKMDEQE-DLAKDMLEQLLKFIP 721
Query: 876 QEDELVKIRKYYETSKEEELKLLDKPEQFLHELAQIPNFAERAQCIIFRSVFSEGITSLH 935
++ ++ + ++ + E++ + + ++FL+E+++I ++ +R Q + F+ F E +
Sbjct: 722 EKSDIDLLEEH-----KHEIERMARADRFLYEMSRIDHYQQRLQALFFKKKFQERLAEAK 776
Query: 936 RKVEIITRASKDLLHVKSVKDILALILAFGNYMNGGNRTRGQADGYSLEILPKLKDVKSR 995
KVE I AS++L+ K ++ +L +ILA GN+MN G RG A G+ + L K+ D KS
Sbjct: 777 PKVEAILLASRELVRSKRLRQMLEVILAIGNFMNKGQ--RGGAYGFRVASLNKIADTKSS 834
Query: 996 -DNGINLVDYVVKYYLRYYDQEAGTEKSVFPLPEPQDFFLASQVKFEDLIKDLRKLKRQL 1054
D I+L+ Y++ +++ + LPE A++V +L K++ L+R L
Sbjct: 835 IDRNISLLHYLIMILEKHFPDILNMPSELQHLPE------AAKVNLAELEKEVGNLRRGL 888
Query: 1055 EASEKQMVVVCKESPKEYLQPFKDKLEEFFQKAKKEHKMEESHLENAQKSFETTVRYFGM 1114
A E ++ + +E F + +F + E L A+ F + +FG
Sbjct: 889 RAVE--VLEYQRRQVREPSDKFVPVMSDFITVSSFSFSELEDQLNEARDKFAKALMHFG- 945
Query: 1115 KPKSGEKEITPSYVFMVWYEFCSDFKTIWKRESKNISKERLKMAQESVSKLTSEKKVETK 1174
+ ++ P F ++ F F A++ + + K+ E +
Sbjct: 946 ---EHDSKMQPDEFFGIFDTFLQAFSE----------------ARQDLEAMRRRKEEEER 986
Query: 1175 KINPTASLKERLRQKE 1190
+ A LKE+ R++E
Sbjct: 987 RARMEAMLKEQ-RERE 1001
>gi|52485606 formin-like 2 [Homo sapiens]
Length = 1092
Score = 179 bits (453), Expect = 2e-44
Identities = 155/566 (27%), Positives = 261/566 (46%), Gaps = 62/566 (10%)
Query: 633 PMEGMASNQQKALPPPPASIPPPPPLPSGLGSLSPAPPMPPVSAGPPLPPPPPPPPPLPP 692
P G AS+ LPPPP +PP P + + PV+ PP+PPPPPPPPP PP
Sbjct: 516 PTMGAASSGP--LPPPPPPLPPSSDTPETVQN-------GPVT--PPMPPPPPPPPPPPP 564
Query: 693 PSSAGPPPPPPPPPLPNSPAPPNPGGPPPAPPPPGLAPPPP----PGLFFGLGSSSSQCP 748
PPPPPPPPPLP PA PP APP P APP P P + F G ++ +
Sbjct: 565 -----PPPPPPPPPLP-GPAAETVPAPPLAPPLPS-APPLPGTSSPTVVFNSGLAAVKI- 616
Query: 749 RKPAIEPSCPMKPLYWTRIQISDRSQNATPTLWDSLEEPDIRDP---SEFEYLFSKDTTQ 805
K I+ M W + + T+++ +++ I + EFE +F K Q
Sbjct: 617 -KKPIKTKFRMPVFNWVAL----KPNQINGTVFNEIDDERILEDLNVDEFEEIF-KTKAQ 670
Query: 806 QKKKPLSETYEK-KNKVKKIIKLLDGKRSQTVGILISSLHLEMKDIQQAIFNVDDSVVDL 864
LS + +K K + LL+ R++ + I + +I +AI D + +
Sbjct: 671 GPAIDLSSSKQKIPQKGSNKVTLLEANRAKNLAITLRKAGKTADEICKAIHVFDLKTLPV 730
Query: 865 ETLAALYENRAQEDELVKIRKYYETSKEEELKLLDKPEQFLHELAQIPNFAERAQCIIFR 924
+ + L E+E VK+ + YE + + L+ L ++F+ + ++I ++ + F
Sbjct: 731 DFVECLMRFLPTENE-VKVLRLYERER-KPLENLSDEDRFMMQFSKIERLMQKMTIMAFI 788
Query: 925 SVFSEGITSLHRKVEIITRASKDLLHVKSVKDILALILAFGNYMNGGNRTRGQADGYSLE 984
F+E I L ++ I AS + + +K IL +ILA GNYMN RG G+ L+
Sbjct: 789 GNFAESIQMLTPQLHAIIAASVSIKSSQKLKKILEIILALGNYMNSSK--RGAVYGFKLQ 846
Query: 985 ILPKLKDVKSRDNGINLVDYVVKYYLRYYDQEAGTEKSVFPLPEPQDFFLASQVKFEDLI 1044
L L D KS D L+ Y+ Y Q + + + + A+ V E+++
Sbjct: 847 SLDLLLDTKSTDRKQTLLHYISNVVKEKYHQVSLFYNELHYVEK------AAAVSLENVL 900
Query: 1045 KDLRKLKRQLEASEKQMVVVCKESPKEYLQPFKDKLEEFFQKAKKEHKMEESHLENAQKS 1104
D+++L+R ++ ++++ + L+EF + + K + + AQ +
Sbjct: 901 LDVKELQRGMDLTKREYT----------MHDHNTLLKEFILNNEGKLKKLQDDAKIAQDA 950
Query: 1105 FETTVRYFGMKPKSGEKEITPSYVFMVWYEFCSDFKTIWKRESKNISKERLKMAQESVSK 1164
F+ V+YFG PK+ PS F V+ F +K +++ ++ R K Q + K
Sbjct: 951 FDDVVKYFGENPKT----TPPSVFFPVFVRFVKAYK-----QAEEENELRKKQEQALMEK 1001
Query: 1165 LTSEKKVETKKINPTASLKERLRQKE 1190
L ++ + ++ + S K + +Q+E
Sbjct: 1002 LLEQEALMEQQDPKSPSHKSKRQQQE 1027
Score = 32.3 bits (72), Expect = 2.8
Identities = 34/145 (23%), Positives = 61/145 (42%), Gaps = 17/145 (11%)
Query: 1025 PLPEPQDFF--LASQVKFEDLIKDLRKLKRQLEASEKQMVVVC-------KESPKEYLQP 1075
P+PEP + A + +L D +L RQ + +EK+ ++C K P Y+Q
Sbjct: 24 PMPEPGELEERFAIVLNAMNLPPDKARLLRQYD-NEKKWELICDQERFQVKNPPHTYIQK 82
Query: 1076 FKDKLEEFFQKAKKEHKMEESH--LENAQKSFETT----VRYFGMKPKSGEKEITPSYVF 1129
K L+ + K +++ES L + S T VR F + G ++ Y+
Sbjct: 83 LKGYLDPAVTRKKFRRRVQESTQVLRELEISLRTNHIGWVREFLNEENKG-LDVLVEYLS 141
Query: 1130 MVWYEFCSDFKTIWKRESKNISKER 1154
Y DF+++ ++ K +
Sbjct: 142 FAQYAVTFDFESVESTVESSVDKSK 166
>gi|149999378 inverted formin 2 isoform 2 [Homo sapiens]
Length = 1240
Score = 168 bits (426), Expect = 2e-41
Identities = 156/535 (29%), Positives = 238/535 (44%), Gaps = 68/535 (12%)
Query: 621 PNDHKDIHAALQPMEGMASNQQKALPPPPASIP-------------PPPPLPS-GLGSLS 666
P DH + L+ + A QQ + PPPP P PPPPLPS G +L
Sbjct: 396 PVDHAQSESILKVSQPRALEQQASTPPPPPPPPLLPGSSAEPPPPPPPPPLPSVGAKALP 455
Query: 667 PAPPMPPVSAGPPLPPPPPPPPPLPPPSSAGPPPPPPPPPLPNSPAPPNP------GGPP 720
APP PP+ + PP PP PP P S PPPPPP P P PP P GPP
Sbjct: 456 TAPPPPPLPGLGAMAPPAPPLPPPLPGSCEFLPPPPPPLPGLGCPPPPPPLLPGMGWGPP 515
Query: 721 PAPPP--PGLAPPPPPG---------LFFGLGSSSSQCPRKPAIEPSCPMKPLYWTRIQI 769
P PPP P PP G + GLGS+ R+ P+ MK L W ++
Sbjct: 516 PPPPPLLPCTCSPPVAGGMEEVIVAQVDHGLGSAWVPSHRR-VNPPTLRMKKLNWQKLPS 574
Query: 770 SDRSQNATPTLWDSLEEPDIR----DPSEFEYLFSKDTTQQKKKPLSETYEKKNKVKKII 825
+ ++ ++W SL PD D S E LFS + K+ + + K K I
Sbjct: 575 NVAREH--NSMWASLSSPDAEAVEPDFSSIERLFSFPAAKPKEPTM--VAPRARKEPKEI 630
Query: 826 KLLDGKRSQTVGILISSLHLEMKDIQQAIFNVDDSVVDLETLAALYENRAQEDELVKIRK 885
LD K+S + I + +++ I D + D+E L L + ++ E+ +R
Sbjct: 631 TFLDAKKSLNLNIFLKQFKCSNEEVAAMIRAGDTTKFDVEVLKQLLKLLPEKHEIENLRA 690
Query: 886 YYETSKEEELKLLDKPEQFLHELAQIPNFAERAQCIIFRSVFSEGITSLHRKVEIITRAS 945
+ EE KL +L LA IP + R +C++ + + + K +++ A
Sbjct: 691 F----TEERAKLASADHFYLLLLA-IPCYQLRIECMLLCEGAAAVLDMVRPKAQLVLAAC 745
Query: 946 KDLLHVKSVKDILALILAFGNYMNGGNRTRGQADGYSLEILPKLKDVKSRDNGINLVDYV 1005
+ LL + + LIL GN++N G+ T G ADG+ + L KL + KS+ N + L+ +V
Sbjct: 746 ESLLTSRQLPIFCQLILRIGNFLNYGSHT-GDADGFKISTLLKLTETKSQQNRVTLLHHV 804
Query: 1006 VKYYLRYYDQEAGTEKSVFPLPE-PQDFFLASQVKFEDL----------IKDLRKLKRQL 1054
+ +EA EKS L + P+D SQ +L +K L + +R++
Sbjct: 805 L--------EEA--EKSHPDLLQLPRDLEQPSQAAGINLEIIRSEASSNLKKLLETERKV 854
Query: 1055 EASEKQMVVVCKESPKEYLQPFKDKLEEFFQKAKKEHKMEESHLENAQK-SFETT 1108
AS ++ E + + F+ E F +K+ ++ + E+AQ+ S E T
Sbjct: 855 SASVAEVQEQYTERLQASISAFRALDELFEAIEQKQRELADYLCEDAQQLSLEDT 909
>gi|149999380 inverted formin 2 isoform 1 [Homo sapiens]
Length = 1249
Score = 168 bits (426), Expect = 2e-41
Identities = 156/535 (29%), Positives = 238/535 (44%), Gaps = 68/535 (12%)
Query: 621 PNDHKDIHAALQPMEGMASNQQKALPPPPASIP-------------PPPPLPS-GLGSLS 666
P DH + L+ + A QQ + PPPP P PPPPLPS G +L
Sbjct: 396 PVDHAQSESILKVSQPRALEQQASTPPPPPPPPLLPGSSAEPPPPPPPPPLPSVGAKALP 455
Query: 667 PAPPMPPVSAGPPLPPPPPPPPPLPPPSSAGPPPPPPPPPLPNSPAPPNP------GGPP 720
APP PP+ + PP PP PP P S PPPPPP P P PP P GPP
Sbjct: 456 TAPPPPPLPGLGAMAPPAPPLPPPLPGSCEFLPPPPPPLPGLGCPPPPPPLLPGMGWGPP 515
Query: 721 PAPPP--PGLAPPPPPG---------LFFGLGSSSSQCPRKPAIEPSCPMKPLYWTRIQI 769
P PPP P PP G + GLGS+ R+ P+ MK L W ++
Sbjct: 516 PPPPPLLPCTCSPPVAGGMEEVIVAQVDHGLGSAWVPSHRR-VNPPTLRMKKLNWQKLPS 574
Query: 770 SDRSQNATPTLWDSLEEPDIR----DPSEFEYLFSKDTTQQKKKPLSETYEKKNKVKKII 825
+ ++ ++W SL PD D S E LFS + K+ + + K K I
Sbjct: 575 NVAREH--NSMWASLSSPDAEAVEPDFSSIERLFSFPAAKPKEPTM--VAPRARKEPKEI 630
Query: 826 KLLDGKRSQTVGILISSLHLEMKDIQQAIFNVDDSVVDLETLAALYENRAQEDELVKIRK 885
LD K+S + I + +++ I D + D+E L L + ++ E+ +R
Sbjct: 631 TFLDAKKSLNLNIFLKQFKCSNEEVAAMIRAGDTTKFDVEVLKQLLKLLPEKHEIENLRA 690
Query: 886 YYETSKEEELKLLDKPEQFLHELAQIPNFAERAQCIIFRSVFSEGITSLHRKVEIITRAS 945
+ EE KL +L LA IP + R +C++ + + + K +++ A
Sbjct: 691 F----TEERAKLASADHFYLLLLA-IPCYQLRIECMLLCEGAAAVLDMVRPKAQLVLAAC 745
Query: 946 KDLLHVKSVKDILALILAFGNYMNGGNRTRGQADGYSLEILPKLKDVKSRDNGINLVDYV 1005
+ LL + + LIL GN++N G+ T G ADG+ + L KL + KS+ N + L+ +V
Sbjct: 746 ESLLTSRQLPIFCQLILRIGNFLNYGSHT-GDADGFKISTLLKLTETKSQQNRVTLLHHV 804
Query: 1006 VKYYLRYYDQEAGTEKSVFPLPE-PQDFFLASQVKFEDL----------IKDLRKLKRQL 1054
+ +EA EKS L + P+D SQ +L +K L + +R++
Sbjct: 805 L--------EEA--EKSHPDLLQLPRDLEQPSQAAGINLEIIRSEASSNLKKLLETERKV 854
Query: 1055 EASEKQMVVVCKESPKEYLQPFKDKLEEFFQKAKKEHKMEESHLENAQK-SFETT 1108
AS ++ E + + F+ E F +K+ ++ + E+AQ+ S E T
Sbjct: 855 SASVAEVQEQYTERLQASISAFRALDELFEAIEQKQRELADYLCEDAQQLSLEDT 909
>gi|145309324 FH2 domain containing 1 [Homo sapiens]
Length = 1143
Score = 152 bits (384), Expect = 2e-36
Identities = 136/517 (26%), Positives = 223/517 (43%), Gaps = 69/517 (13%)
Query: 663 GSLSPAPPM----PPVSAGPPLPPPPPPPPPLPPPSSAGPPPPPPPPPLPNSPAPPNPGG 718
G+++ AP P A PP PPPPPP PP P PPPPPP PP PG
Sbjct: 16 GNIATAPGFMIGQTPPPAPPPPPPPPPPSPPCSCSREECPSSPPPPPP------PPLPGE 69
Query: 719 PPPAPPPPGLAPPPPPGLFFGLGSSSSQCPRKPAIEPSCPMKPLYWTRI-QISDRSQNAT 777
PP PPPPGL P + LG M+ +W I + R +
Sbjct: 70 PPIPPPPPGLPPTTHMNGYSHLGKKKR-------------MRSFFWKTIPEEQVRGKTNI 116
Query: 778 PTLWDSLEEPDIRDPSEFEYLF--SKDTTQQKKKPLSETYEKK-NKVKKIIKLLDGKRSQ 834
TL E D E LF +DTT+ T + ++ I +LD KRS
Sbjct: 117 WTLAARQEHHYQIDTKTIEELFGQQEDTTKSSLPRRGRTLNSSFREAREEITILDAKRSM 176
Query: 835 TVGILISSLHLEMKDIQQAIFNVDDSVVDLETLAALYENRAQEDELVKIRKYYETSKEEE 894
+GI + + I + I ETL + + +E+ K++ + +
Sbjct: 177 NIGIFLKQFKKSPRSIVEDIHQGKSEHYGSETLREFLKFLPESEEVKKLKAF-----SGD 231
Query: 895 LKLLDKPEQFLHELAQIPNFAERAQCIIFRSVFSEGITSLHRKVEIITRASKDLLHVKSV 954
+ L + FL+ L Q+PN++ R + ++ + F +SL+ + ++ A K+L+ + +
Sbjct: 232 VSKLSLADSFLYGLIQVPNYSLRIEAMVLKKEFLPSCSSLYTDITVLRTAIKELMSCEEL 291
Query: 955 KDILALILAFGNYMNGGNRTRGQADGYSLEILPKLKDVKSRDNGINLVDYVVKYYLRYYD 1014
IL L+L GN MN G G A G+ L L KL D K+ G+NL+ +V
Sbjct: 292 HSILHLVLQAGNIMNAGGYA-GNAVGFKLSSLLKLADTKANKPGMNLLHFVA-------- 342
Query: 1015 QEAGTEKSVFPLPEPQDFFLASQVKFEDLIKDLRKLKR-QLEASEKQ--MVVVCKESPKE 1071
QEA + ++ + F + + ++K R LE +E + ++ V +S KE
Sbjct: 343 QEAQKKDTIL-------------LNFSEKLHHVQKTARLSLENTEAELHLLFVRTKSLKE 389
Query: 1072 YLQ---PFKDKLEEFFQKAKKEHKMEESHLENAQKSFETTVRYFGMKPKSGEKEITPSYV 1128
+Q ++E+F Q A ++ + E + Q T + +F +K +
Sbjct: 390 NIQRDGELCQQMEDFLQFAIEKLRELECWKQELQDEAYTLIDFF----CEDKKTMKLDEC 445
Query: 1129 FMVWYEFCSDFKTIWK----RESKNISK-ERLKMAQE 1160
F ++ +FC+ F K RE++ + + +RLK ++
Sbjct: 446 FQIFRDFCTKFNKAVKDNHDREAQELRQLQRLKEQEQ 482
>gi|119120861 formin-like 3 isoform 2 [Homo sapiens]
Length = 976
Score = 138 bits (348), Expect = 3e-32
Identities = 139/562 (24%), Positives = 240/562 (42%), Gaps = 65/562 (11%)
Query: 631 LQP-MEGMASNQQKALPPP-PASIPPPPPLPSGLGSLSPAPPMPPVSAGPPLPPPPPPPP 688
L+P + G+ S +AL PA + P PS L L+PAPP V PP P PP PPP
Sbjct: 420 LEPNVRGLESVDSEALARVGPAELSEGMP-PSDLDLLAPAPPPEEVLPLPPPPAPPLPPP 478
Query: 689 PLPPPSSAGPPPPPPPPPLPNSPAPPNPGGPPPAPPPPGLAPPPPPGLFFGLGSSSSQCP 748
PPPLP+ PPAPP PG A P + +G S+ +
Sbjct: 479 ---------------PPPLPDK--------CPPAPPLPGAA----PSVVLTVGLSAIRI- 510
Query: 749 RKPAIEPSCPMKPLYWTRIQISDRSQNATPTLWDSLEEPDIRDPSEFEYLFSKDTTQQKK 808
K I+ + WT ++ + S L D D+ D +FE LF
Sbjct: 511 -KKPIKTKFRLPVFNWTALKPNQISGTVFSELDDEKILEDL-DLDKFEELFKTKAQGPAL 568
Query: 809 KPLSETYEKKNKVKKIIKLLDGKRSQTVGILISSLHLEMKDIQQAIFNVDDSVVDLETLA 868
+ + K + LL+ R++ + I + ++I +AI D + ++ +
Sbjct: 569 DLICSKNKTAQKAASKVTLLEANRAKNLAITLRKAGRSAEEICRAIHTFDLQTLPVDFVE 628
Query: 869 ALYENRAQEDELVKIRKYYETSKEEELKLLDKPEQFLHELAQIPNFAERAQCIIFRSVFS 928
L E E VK+ + YE + + L+ L ++F+ +++ +R + F F
Sbjct: 629 CLMRFLPTEAE-VKLLRQYERER-QPLEELAAEDRFMLLFSKVERLTQRMAGMAFLGNFQ 686
Query: 929 EGITSLHRKVEIITRASKDLLHVKSVKDILALILAFGNYMNGGNRTRGQADGYSLEILPK 988
+ + L ++ I AS + + +K +L +ILA GNYMN RG G+ L+ L
Sbjct: 687 DNLQMLTPQLNAIIAASASVKSSQKLKQMLEIILALGNYMNSSK--RGAVYGFKLQSLDL 744
Query: 989 LKDVKSRDNGINLVDYVVKYYLRYYDQEAGTEKSVFPLPEPQDFFLASQVKFEDLIKDLR 1048
L D KS D + L+ ++ Y A + + + A+ V E+++ D++
Sbjct: 745 LLDTKSTDRKMTLLHFIALTVKEKYPDLANFWHELHFVEK------AAAVSLENVLLDVK 798
Query: 1049 KLKRQLEASEKQMVVVCKESPKEYLQPFKDKLEEFFQKAKKEHKMEESHLENAQKSFETT 1108
+L R +E ++ + + +L + KL++ + AK A++++
Sbjct: 799 ELGRGMELIRRECSIHDNSVLRNFLSTNEGKLDKLQRDAK-----------TAEEAYNAV 847
Query: 1109 VRYFGMKPKSGEKEITPSYVFMVWYEFCSDFKTIWKRESKNISKERLKMAQESVSKLTSE 1168
VRYFG PK+ PS F V+ F +K + E +N ++++ +
Sbjct: 848 VRYFGESPKT----TPPSVFFPVFVRFIRSYK---EAEQENEARKKQEEVMREKQLAQEA 900
Query: 1169 KKVETKKINPTASLKERLRQKE 1190
KK++ K T S + + +Q+E
Sbjct: 901 KKLDAK----TPSQRNKWQQQE 918
>gi|119120874 formin-like 3 isoform 1 [Homo sapiens]
Length = 1027
Score = 138 bits (348), Expect = 3e-32
Identities = 139/562 (24%), Positives = 240/562 (42%), Gaps = 65/562 (11%)
Query: 631 LQP-MEGMASNQQKALPPP-PASIPPPPPLPSGLGSLSPAPPMPPVSAGPPLPPPPPPPP 688
L+P + G+ S +AL PA + P PS L L+PAPP V PP P PP PPP
Sbjct: 471 LEPNVRGLESVDSEALARVGPAELSEGMP-PSDLDLLAPAPPPEEVLPLPPPPAPPLPPP 529
Query: 689 PLPPPSSAGPPPPPPPPPLPNSPAPPNPGGPPPAPPPPGLAPPPPPGLFFGLGSSSSQCP 748
PPPLP+ PPAPP PG A P + +G S+ +
Sbjct: 530 ---------------PPPLPDK--------CPPAPPLPGAA----PSVVLTVGLSAIRI- 561
Query: 749 RKPAIEPSCPMKPLYWTRIQISDRSQNATPTLWDSLEEPDIRDPSEFEYLFSKDTTQQKK 808
K I+ + WT ++ + S L D D+ D +FE LF
Sbjct: 562 -KKPIKTKFRLPVFNWTALKPNQISGTVFSELDDEKILEDL-DLDKFEELFKTKAQGPAL 619
Query: 809 KPLSETYEKKNKVKKIIKLLDGKRSQTVGILISSLHLEMKDIQQAIFNVDDSVVDLETLA 868
+ + K + LL+ R++ + I + ++I +AI D + ++ +
Sbjct: 620 DLICSKNKTAQKAASKVTLLEANRAKNLAITLRKAGRSAEEICRAIHTFDLQTLPVDFVE 679
Query: 869 ALYENRAQEDELVKIRKYYETSKEEELKLLDKPEQFLHELAQIPNFAERAQCIIFRSVFS 928
L E E VK+ + YE + + L+ L ++F+ +++ +R + F F
Sbjct: 680 CLMRFLPTEAE-VKLLRQYERER-QPLEELAAEDRFMLLFSKVERLTQRMAGMAFLGNFQ 737
Query: 929 EGITSLHRKVEIITRASKDLLHVKSVKDILALILAFGNYMNGGNRTRGQADGYSLEILPK 988
+ + L ++ I AS + + +K +L +ILA GNYMN RG G+ L+ L
Sbjct: 738 DNLQMLTPQLNAIIAASASVKSSQKLKQMLEIILALGNYMNSSK--RGAVYGFKLQSLDL 795
Query: 989 LKDVKSRDNGINLVDYVVKYYLRYYDQEAGTEKSVFPLPEPQDFFLASQVKFEDLIKDLR 1048
L D KS D + L+ ++ Y A + + + A+ V E+++ D++
Sbjct: 796 LLDTKSTDRKMTLLHFIALTVKEKYPDLANFWHELHFVEK------AAAVSLENVLLDVK 849
Query: 1049 KLKRQLEASEKQMVVVCKESPKEYLQPFKDKLEEFFQKAKKEHKMEESHLENAQKSFETT 1108
+L R +E ++ + + +L + KL++ + AK A++++
Sbjct: 850 ELGRGMELIRRECSIHDNSVLRNFLSTNEGKLDKLQRDAK-----------TAEEAYNAV 898
Query: 1109 VRYFGMKPKSGEKEITPSYVFMVWYEFCSDFKTIWKRESKNISKERLKMAQESVSKLTSE 1168
VRYFG PK+ PS F V+ F +K + E +N ++++ +
Sbjct: 899 VRYFGESPKT----TPPSVFFPVFVRFIRSYK---EAEQENEARKKQEEVMREKQLAQEA 951
Query: 1169 KKVETKKINPTASLKERLRQKE 1190
KK++ K T S + + +Q+E
Sbjct: 952 KKLDAK----TPSQRNKWQQQE 969
>gi|223278403 glutamate receptor, ionotropic, delta 2 (Grid2)
interacting protein [Homo sapiens]
Length = 1211
Score = 127 bits (319), Expect = 6e-29
Identities = 117/511 (22%), Positives = 205/511 (40%), Gaps = 86/511 (16%)
Query: 645 LPPPPASIPPPPPLP---------SGLGSLSPAPPMPPVSAGPPLPPPPPPPPPLPPPSS 695
+PPPP S PPPPPLP S GS PA + P PPPPPPPL
Sbjct: 749 IPPPPLSPPPPPPLPFHDAKPSSRSSDGSRGPAQALAKPLTQLSHPVPPPPPPPL----- 803
Query: 696 AGPPPPPPPPPLPNSPAPPNPGGPPPAPPPPGLAPPPPPGLFFGLGSSSSQCPRKPAIEP 755
PPP P PP L GLG S+
Sbjct: 804 ------PPP------------------------VPCAPPMLSRGLGHRRSETSH------ 827
Query: 756 SCPMKPLYWTRIQISDRSQNATPTLWDSLEEPD----IRDPSEFEYLFSKDTTQQKKKPL 811
+K L W ++ +N+ T+W L E + D ++ L TQ+ KP+
Sbjct: 828 -MSVKRLRWEQV------ENSEGTIWGQLGEDSDYDKLSDMVKYLDLELHFGTQKPAKPV 880
Query: 812 --SETYEKKNKVKKIIKLLDGKRSQTVGILISSLHLEMKDIQQAIFNVDDSVVDLETLAA 869
E + K K+++++L K++ IL++ L L +++Q + +++ ++ LA
Sbjct: 881 PGPEPFRK----KEVVEILSHKKAYNTSILLAHLKLSPAELRQVLMSMEPRRLEPAHLAQ 936
Query: 870 LYENRAQEDELVKIRKYYETSKEEELKLLDKPEQFLHELAQIPNFAERAQCIIFRSVFSE 929
L DE + + + E L +P+QF+ ++ +P + R + + F++ E
Sbjct: 937 LLLFAPDADEEQRYQAFREAPGR-----LSEPDQFVLQMLSVPEYKTRLRSLHFQATLQE 991
Query: 930 GITSLHRKVEIITRASKDLLHVKSVKDILALILAFGNYMNGGNRTRGQADGYSLEILPKL 989
+ +E + +AS +L + + + IL +LA GNY+N G + G+ + L +L
Sbjct: 992 KTEEIRGSLECLRQASLELKNSRKLAKILEFVLAMGNYLNDGQPKTNKTTGFKINFLTEL 1051
Query: 990 KDVKSRDNGINLVDYVVKYYLRYYDQEAGTEKSVFPLPEPQDFFLASQVKFEDLIKDLRK 1049
K+ D + + K +++ + G + + +P LA++V L DL
Sbjct: 1052 NSTKTVDGKSTFLHILAKSLSQHFPELLGFAQDLPTVP------LAAKVNQRALTSDL-- 1103
Query: 1050 LKRQLEASEKQMVVVCKESPKEYLQPFKDKLEEFFQKAKKEHKMEESHLENAQKSFETTV 1109
L + ++ C+ F + F + A+ + + A + +
Sbjct: 1104 --ADLHGTISEIQDACQSISPSSEDKFAMVMSSFLETAQPALRALDGLQREAMEELGKAL 1161
Query: 1110 RYFGMKPKSGEKEITPSYVFMVWYEFCSDFK 1140
+FG K T F ++ EF S F+
Sbjct: 1162 AFFG----EDSKATTSEAFFGIFAEFMSKFE 1188
Score = 39.7 bits (91), Expect = 0.017
Identities = 28/100 (28%), Positives = 44/100 (44%), Gaps = 6/100 (6%)
Query: 627 IHAALQPMEGMASNQQKALPPPPASIPPPPPLPSGLG----SLSPAPPMPPVSAGPPLPP 682
++++ + G S + + P P ++ P SG+ L P+P P+ +G P
Sbjct: 563 LNSSFKGKMGTVSKSRASPPGPSPAVTTGPRTLSGVSWPSERLLPSPCYHPLCSGGLASP 622
Query: 683 PPPPPPPLPP-PSSAGPPPPPPPPPL-PNSPAPPNPGGPP 720
P SS P P P P P+ P+SP P+P PP
Sbjct: 623 SSSESHPYASLDSSRAPSPQPGPGPICPDSPPSPDPTRPP 662
Score = 38.1 bits (87), Expect = 0.050
Identities = 31/109 (28%), Positives = 42/109 (38%), Gaps = 20/109 (18%)
Query: 600 TRSNQLVPKKLNISSLSQLSPPNDHKDIHAALQPMEGMASNQQKALPPPPASIPPPPPLP 659
+R N K+ S S+ SPP + + + G++ ++ LP P PL
Sbjct: 561 SRLNSSFKGKMGTVSKSRASPPGPSPAVTTGPRTLSGVSWPSERLLPSPCYH-----PLC 615
Query: 660 SGLGSLSPAP--------------PMPPVSAGPPLPPPPPPPPPLPPPS 694
SG G SP+ P P GP P PP P P PPS
Sbjct: 616 SG-GLASPSSSESHPYASLDSSRAPSPQPGPGPICPDSPPSPDPTRPPS 663
>gi|58331242 formin homology 2 domain containing 3 [Homo sapiens]
Length = 1439
Score = 120 bits (302), Expect = 6e-27
Identities = 116/466 (24%), Positives = 203/466 (43%), Gaps = 38/466 (8%)
Query: 685 PPPPPLPPPSSAGPPPPPPPPPLPNSPAPPNPGGPPPAPPPPGLAPPPPPGLFFGLGSSS 744
P PPP PPP+ G PPPPPPP L + P PP PG L PPPP G
Sbjct: 844 PGPPPPPPPTFLGLPPPPPPPLLDSIPPPPVPG---------NLLVPPPPVFNAPQGLGW 894
Query: 745 SQCPR-KPAIEPSCPMKPLYWTRIQISD----RSQNATPTLWDSLEEPDIRDPSEFEYLF 799
SQ PR +P L+W ++ D ++ LW L EP D S E+LF
Sbjct: 895 SQVPRGQPTFTKKKKTIRLFWNEVRPFDWPCKNNRRCREFLWSKL-EPIKVDTSRLEHLF 953
Query: 800 SKDTTQQKKKPLSETYEKKNKVKKIIKLLDGKRSQTVGILISSLHLEMKDIQQAIFNVDD 859
++ K+ +S+ K ++II +LD KRS + I ++ L + I+ AI N D+
Sbjct: 954 E---SKSKELSVSKKTAADGKRQEII-VLDSKRSNAINIGLTVLP-PPRTIKIAILNFDE 1008
Query: 860 SVVDLETLAALYENRAQEDELVKIRKYYETSKEEELKLLDKPEQFLHELAQIPNFAERAQ 919
++ E + + ++E KI++ + E L EQFL L+ I + R
Sbjct: 1009 YALNKEGIEKILTMIPTDEEKQKIQEAQLANPEIP---LGSAEQFLLTLSSISELSARLH 1065
Query: 920 CIIFRSVFSEGITSLHRKVEIITRASKDLLHVKSVKDILALILAFGNYMNGGNRTRGQAD 979
F+ + + + + L + K++ IL+ +LA GN++NG N A
Sbjct: 1066 LWAFKMDYETTEKEVAEPLLDLKEGIDQLENNKTLGFILSTLLAIGNFLNGTN-----AK 1120
Query: 980 GYSLEILPKLKDVKSRDNGINLVDYVVKYYLRYYDQEAGTEKSVFPLPEPQDFFLASQVK 1039
+ L L K+ +VK + +L+ +V + + + + + +++V
Sbjct: 1121 AFELSYLEKVPEVKDTVHKQSLLHHVCTMVVENFPDSSDLYSEIGAITR------SAKVD 1174
Query: 1040 FEDLIKDLRKLKRQLEASEKQMVVVCKESPKEYLQPFKDKLEEFFQKAKKEHKMEESHLE 1099
F+ L +L +++R+ +AS + + K K L K ++ EF + + + +
Sbjct: 1175 FDQLQDNLCQMERRCKASWDHLKAIAKHEMKPVL---KQRMSEFLKDCAERIIILKIVHR 1231
Query: 1100 NAQKSFETTVRYFGMKPKSGEKEITPSYVFMVWYEFCSDFKTIWKR 1145
F + + + G P +E+ + + EF +++T +R
Sbjct: 1232 RIINRFHSFLLFMG-HPPYAIREVNINKFCRIISEFALEYRTTRER 1276
>gi|118572599 formin homology 2 domain containing 1 [Homo sapiens]
Length = 1164
Score = 112 bits (280), Expect = 2e-24
Identities = 120/508 (23%), Positives = 208/508 (40%), Gaps = 63/508 (12%)
Query: 684 PPPPPPLPPPSSAGPPPP-PPPPPLPNSPAPPNPGGPPPAPPPPGLAPPPPPGLFFGLGS 742
P P PPLP S PPPP PPPPP+ GP P PPP LA P P +
Sbjct: 570 PAPSPPLPLLSGVPPPPPLPPPPPIK---------GPFPPPPPLPLAAPLPHSV------ 614
Query: 743 SSSQCPRKPAIEPSCPMKPLYWTRIQ------ISDRSQNATPTLWDSLEEPDIRDPSEFE 796
P A+ L+W ++ +S TLW SL+ + D + E
Sbjct: 615 -----PDSSALPTKRKTVKLFWRELKLAGGHGVSASRFGPCATLWASLDPVSV-DTARLE 668
Query: 797 YLFSKDTTQQKKKPLSETYEKKNKVKKIIKLLDGKRSQTVGILISSLHLEMKDIQQAIFN 856
+LF + + K + + + + + +LD KRS + I +++L + I+ A+ N
Sbjct: 669 HLF-----ESRAKEVLPSKKAGEGRRTMTTVLDPKRSNAINIGLTTLP-PVHVIKAALLN 722
Query: 857 VDDSVVDLETLAALYENRAQEDELVKIRKYYETSKEEELKLLDKP----EQFLHELAQIP 912
D+ V + + L E+E KI +E +L D P E FL LA I
Sbjct: 723 FDEFAVSKDGIEKLLTMMPTEEERQKI-------EEAQLANPDIPLGPAENFLMTLASIG 775
Query: 913 NFAERAQCIIFRSVFSEGITSLHRKVEIITRASKDLLHVKSVKDILALILAFGNYMNGGN 972
A R Q F+ + + + + + L+ + + ILA +LA GN++NG
Sbjct: 776 GLAARLQLWAFKLDYDSMEREIAEPLFDLKVGMEQLVQNATFRCILATLLAVGNFLNG-- 833
Query: 973 RTRGQADGYSLEILPKLKDVKSRDNGINLVDYVVKYYLRYYDQEAGTEKSVFPLPEPQDF 1032
Q+ G+ L L K+ +VK +L+ ++ L+ + + + L
Sbjct: 834 ---SQSSGFELSYLEKVSEVKDTVRRQSLLHHLCSLVLQTRPESSDLYSEIPALTR---- 886
Query: 1033 FLASQVKFEDLIKDLRKLKRQLEASEKQMVVVCKESPKEYLQPFKDKLEEFFQKAKKEHK 1092
++V FE L ++L +L+R+ A+E+ + + K E + +L F + +
Sbjct: 887 --CAKVDFEQLTENLGQLERRSRAAEESLRSLAKH---ELAPALRARLTHFLDQCARRVA 941
Query: 1093 MEESHLENAQKSFETTVRYFGMKPKSGEKEITPSYVFMVWYEFCSDFKTIWKRESKNISK 1152
M F + Y G P++ +E+ EF +++T +R + +
Sbjct: 942 MLRIVHRRVCNRFHAFLLYLGYTPQAA-REVRIMQFCHTLREFALEYRTCRERV---LQQ 997
Query: 1153 ERLKMAQESVSKLTSEKKVETKKINPTA 1180
++ + +K ET+K + A
Sbjct: 998 QQKQATYRERNKTRGRMITETEKFSGVA 1025
>gi|11386183 WAS protein family, member 2 [Homo sapiens]
Length = 498
Score = 105 bits (262), Expect = 3e-22
Identities = 51/114 (44%), Positives = 55/114 (48%), Gaps = 13/114 (11%)
Query: 628 HAALQPMEGMASNQQKALPPPPASIPPPPPLPSGLGSLSPAPPMPPVSAGPPLPPPPPPP 687
H P G + PPPA PPPPP+ + PP PPV G P PPPP P
Sbjct: 299 HPPPAPPLGSPPGPKPGFAPPPAPPPPPPPM------IGIPPPPPPVGFGSPGTPPPPSP 352
Query: 688 PPLPPPSSAGPPPPPPPPPLPNSPAPPNP-------GGPPPAPPPPGLAPPPPP 734
P PP PPPPPPPP + P P P G PPP PPPP PPPPP
Sbjct: 353 PSFPPHPDFAAPPPPPPPPAADYPTLPPPPLSQPTGGAPPPPPPPPPPGPPPPP 406
Score = 93.2 bits (230), Expect = 1e-18
Identities = 57/129 (44%), Positives = 62/129 (48%), Gaps = 17/129 (13%)
Query: 613 SSLSQLSPPNDHKDIHAALQPMEGMASNQQKALPPPPASIPPPPPLPSGLGSL-SPAPPM 671
SS+ S P + + P G A PPPP PPPP P G GS +P PP
Sbjct: 292 SSVVSPSHPPPAPPLGSPPGPKPGFAPPPAPPPPPPPMIGIPPPPPPVGFGSPGTPPPPS 351
Query: 672 PPVS------AGPPLPPPPP-------PPPPLPPPSSAGPPPPPPPPPLPNSPAPPNPG- 717
PP A PP PPPPP PPPPL P+ G PPPPPPPP P P PP G
Sbjct: 352 PPSFPPHPDFAAPPPPPPPPAADYPTLPPPPLSQPTG-GAPPPPPPPPPPGPPPPPFTGA 410
Query: 718 -GPPPAPPP 725
G P PPP
Sbjct: 411 DGQPAIPPP 419
Score = 91.3 bits (225), Expect = 5e-18
Identities = 60/164 (36%), Positives = 67/164 (40%), Gaps = 30/164 (18%)
Query: 620 PPNDHKDIHAALQPMEGMASNQQKALPPPPASIPPPPPLPSGLGSLSPA----------P 669
PP D ++ P S + LPPPPA P G G P P
Sbjct: 247 PPPPQSDSASSPSP-----SFSEDNLPPPPAEFSYPVDNQRGSGLAGPKRSSVVSPSHPP 301
Query: 670 PMPPVS---------AGPPLPPPPPPP----PPLPPPSSAGPPPPPPPPPLPNSPAPPNP 716
P PP+ A PP PPPPPPP PP PPP G P PPPP P+ P P+
Sbjct: 302 PAPPLGSPPGPKPGFAPPPAPPPPPPPMIGIPPPPPPVGFGSPGTPPPPSPPSFPPHPDF 361
Query: 717 GGPPPAPPPPGLAPP--PPPGLFFGLGSSSSQCPRKPAIEPSCP 758
PPP PPPP P PPP L G + P P P P
Sbjct: 362 AAPPPPPPPPAADYPTLPPPPLSQPTGGAPPPPPPPPPPGPPPP 405
Score = 68.6 bits (166), Expect = 3e-11
Identities = 33/73 (45%), Positives = 40/73 (54%), Gaps = 3/73 (4%)
Query: 644 ALPPPP--ASIPPPPPLPSGLGSLSPAPPMP-PVSAGPPLPPPPPPPPPLPPPSSAGPPP 700
+ PP P A+ PPPPP P+ P PP+ P PP PPPPPPP P PPP +
Sbjct: 354 SFPPHPDFAAPPPPPPPPAADYPTLPPPPLSQPTGGAPPPPPPPPPPGPPPPPFTGADGQ 413
Query: 701 PPPPPPLPNSPAP 713
P PPPL ++ P
Sbjct: 414 PAIPPPLSDTTKP 426
Score = 53.9 bits (128), Expect = 9e-07
Identities = 48/144 (33%), Positives = 53/144 (36%), Gaps = 46/144 (31%)
Query: 655 PPPLPSGLGSLSPAPPMPPVSAGPPLPPPPPPPPPLPPPSSAGPPPPPP----------- 703
PP L GS+ + V A PPP P PS + PPP
Sbjct: 225 PPTLVYQNGSIGC---VENVDASSYPPPPQSDSASSPSPSFSEDNLPPPPAEFSYPVDNQ 281
Query: 704 ------------------PPPLP--NSPAPPNPG-GPPPAPPPP-----GLAPPPPPGLF 737
PPP P SP P PG PPPAPPPP G+ PPPPP
Sbjct: 282 RGSGLAGPKRSSVVSPSHPPPAPPLGSPPGPKPGFAPPPAPPPPPPPMIGIPPPPPP--- 338
Query: 738 FGLGSSSSQCPRKPAIEPSCPMKP 761
G GS + P P PS P P
Sbjct: 339 VGFGSPGTPPPPSP---PSFPPHP 359
>gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo
sapiens]
Length = 505
Score = 100 bits (248), Expect = 1e-20
Identities = 55/104 (52%), Positives = 58/104 (55%), Gaps = 16/104 (15%)
Query: 646 PPPPASIPPPPPLPSGLGSLSPAPPMPPVSAGPPLPP-------PPPPP----PPLPP-- 692
PPPP + PPPP G G+ P P P +A PP PP PPPPP PP PP
Sbjct: 291 PPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPPPPPNRMYPPPPPAL 350
Query: 693 PSSAGPPPPPPPPPLPNSPAPPNPGGPPPAPPPPGLAPPPPPGL 736
PSSA P PPPPPP P P PPP PPPPG PPPPPGL
Sbjct: 351 PSSA-PSGPPPPPPSVLGVGPVAPPPPPPPPPPPG--PPPPPGL 391
Score = 87.0 bits (214), Expect = 9e-17
Identities = 50/114 (43%), Positives = 54/114 (47%), Gaps = 20/114 (17%)
Query: 668 APPMPPVSAGPPLPPPPPP----PPPLPPPSSAGPPPPP-------PPPPLPNSPA---- 712
APP PP S G P PPPPPP PPP P PPPPP PPPP P+ P+
Sbjct: 276 APPPPPPSRGGPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVP 335
Query: 713 --PPNPGGPPPAPPPPGLA---PPPPPGLFFGLGSSSSQCPRKPAIEPSCPMKP 761
PPN PPP P P A PPPPP G+G + P P P P P
Sbjct: 336 PPPPNRMYPPPPPALPSSAPSGPPPPPPSVLGVGPVAPPPPPPPPPPPGPPPPP 389
Score = 79.3 bits (194), Expect = 2e-14
Identities = 48/104 (46%), Positives = 50/104 (48%), Gaps = 30/104 (28%)
Query: 646 PPPPA---SIPPPPPLPSGLGSLSPAPPMPPVSAGPPLPP----PPPPP---------PP 689
PPPPA PPPPP + + P PP P A PP PP PPPPP PP
Sbjct: 300 PPPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPPPPPNRMYPPPPPALPSSAPSGPP 359
Query: 690 LPPPSSAG------PPPPPPPPPLPNSPAPPNPGGPPPAPPPPG 727
PPPS G PPPPPPPPP P PP PPP P G
Sbjct: 360 PPPPSVLGVGPVAPPPPPPPPPP----PGPP----PPPGLPSDG 395
Score = 73.2 bits (178), Expect = 1e-12
Identities = 38/82 (46%), Positives = 42/82 (51%), Gaps = 8/82 (9%)
Query: 639 SNQQKALPPPPASI---PPPPPLPSGLGSLSPAPPMPPVSAGPPLPPPPPPPPPLPPPSS 695
S A+PPPP + PPPP LPS S P PP + GP PPPPPPPPP P
Sbjct: 328 SRPSVAVPPPPPNRMYPPPPPALPSSAPSGPPPPPPSVLGVGPVAPPPPPPPPPPP---- 383
Query: 696 AGPPPPPPPPPLPNSPAPPNPG 717
GPPPPP P + P G
Sbjct: 384 -GPPPPPGLPSDGDHQVPTTAG 404
Score = 65.9 bits (159), Expect = 2e-10
Identities = 37/80 (46%), Positives = 41/80 (51%), Gaps = 21/80 (26%)
Query: 644 ALPPPPAS-----IPPPPPLPSGLGSLSPAPPMPPVSAGPPLPPPPPP---------PPP 689
A PPPP S +PPPPP + P PP S+ P PPPPPP PPP
Sbjct: 321 APPPPPPSRPSVAVPPPPP-----NRMYPPPPPALPSSAPSGPPPPPPSVLGVGPVAPPP 375
Query: 690 LPPPSSAGPPPPPPPPPLPN 709
PPP PP PPPPP LP+
Sbjct: 376 PPPPPP--PPGPPPPPGLPS 393
Score = 35.8 bits (81), Expect = 0.25
Identities = 26/78 (33%), Positives = 31/78 (39%), Gaps = 32/78 (41%)
Query: 633 PMEGMASNQQKALPPPPASI-------PPPPPLPSGLGSLSPAPPMPPVSAGPPLPPPPP 685
P + S+ PPPP S+ PPPPP P P PP P P
Sbjct: 346 PPPALPSSAPSGPPPPPPSVLGVGPVAPPPPPPP-------PPPPGP------------P 386
Query: 686 PPPPLPP------PSSAG 697
PPP LP P++AG
Sbjct: 387 PPPGLPSDGDHQVPTTAG 404
>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
subunit [Homo sapiens]
Length = 551
Score = 96.3 bits (238), Expect = 2e-19
Identities = 74/189 (39%), Positives = 84/189 (44%), Gaps = 46/189 (24%)
Query: 578 RNVCVQTDRETFLKPCESES-KTTRSNQLVPKKLNISSLSQLSPPNDHKDIHAALQPMEG 636
+N V + FL E +S KTT+S Q+ S + PP A P G
Sbjct: 152 QNPVVTPCNKQFLSQFEMQSRKTTQSGQM-------SGEGKAGPPGGSS---RAAFPQGG 201
Query: 637 MASNQQKALPPPPASIP-------PPPPLPSGLGSLSPAPPMPPVSA-GPPLPPPPPPPP 688
+ P P PPPP P+G PP PP+ GPP PP PPPP
Sbjct: 202 RGRGRFPGAVPGGDRFPGPAGPGGPPPPFPAG-----QTPPRPPLGPPGPPGPPGPPPPG 256
Query: 689 PLPPPSSAGPP-----PPPP----------PP--PLPNSPAPPNPG-GPPPAPPPP--GL 728
+ PP AGPP PPPP PP PLP P PP PG GPPP PPPP G
Sbjct: 257 QVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGPPPPVPGYGPPPGPPPPQQG- 315
Query: 729 APPPPPGLF 737
PPPPPG F
Sbjct: 316 -PPPPPGPF 323
Score = 89.0 bits (219), Expect = 2e-17
Identities = 48/102 (47%), Positives = 51/102 (50%), Gaps = 16/102 (15%)
Query: 646 PPPPASIPPPPPL-PSGLGSLSPAPPM--------PPVSAGPPLPPPPPP---PPPLPPP 693
PPPP + PPP P G P P + PP+ PP PPPP P PPP PPP
Sbjct: 252 PPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGPPPPVPGYGPPPGPPP 311
Query: 694 SSAGPPPPPPPPPLPNSPAPPNPGGPPPAPPPPGLAPPPPPG 735
GPPPPP P P P PP P GPP PP P PPPG
Sbjct: 312 PQQGPPPPPGPFP----PRPPGPLGPPLTLAPPPHLPGPPPG 349
Score = 86.3 bits (212), Expect = 2e-16
Identities = 53/119 (44%), Positives = 58/119 (48%), Gaps = 17/119 (14%)
Query: 646 PPPPASIPPPPPLPSGLGSLSPAPPMPPVSAGPPLPPPPPPPPPLPPPSSAGPPPPPPP- 704
PPPP P P LG L P PP P GPP PPPP P PPP GP PP PP
Sbjct: 273 PPPPVLFPGQPFGQPPLGPLPPGPPPPVPGYGPPPGPPPPQQGPPPPP---GPFPPRPPG 329
Query: 705 ---PPLPNSPAPPNPGGPPPAPPP-----PGLAPPPPPGLFFGLGSSSSQCPRKPAIEP 755
PPL +P P PG PP APPP P PPP G+ +S S+ P P +P
Sbjct: 330 PLGPPLTLAPPPHLPGPPPGAPPPAPHVNPAFFPPPTNS---GMPTSDSRGP--PPTDP 383
Score = 72.8 bits (177), Expect = 2e-12
Identities = 43/102 (42%), Positives = 45/102 (44%), Gaps = 23/102 (22%)
Query: 646 PPPPASIPPPPPLPSGLGSLSPAPPMPPVSAGPPLPPPPPPPPPLPPPSSAGPPPPPP-- 703
PPPP PPPPP P PP PP GPPL PPP P PPP G PPP P
Sbjct: 309 PPPPQQGPPPPP--------GPFPPRPPGPLGPPLTLAPPPHLPGPPP---GAPPPAPHV 357
Query: 704 -----PPPLPNSPAPPNPGGPPPA-----PPPPGLAPPPPPG 735
PPP + + GPPP PPP PPG
Sbjct: 358 NPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPPYDRGDYGPPG 399
>gi|153792074 proline rich 12 [Homo sapiens]
Length = 2036
Score = 94.0 bits (232), Expect = 8e-19
Identities = 54/126 (42%), Positives = 62/126 (49%), Gaps = 15/126 (11%)
Query: 633 PMEGMASNQQKALPP--PPASIPPPPPLPSGLGSLSPAPPMPPVSAGPPLPPPPPPPPPL 690
P+ G PP P A++P PPPLP + S P PP+ PPP PPP P
Sbjct: 1409 PLAGPKDTSTPDGPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLL--EEKPPPTPPPAPT 1466
Query: 691 PPPSSAGPPPPPPPPPLPNSPAPPNPGGP-PPAPPPPGLAPPPPPGLFFGLGSSSSQCPR 749
P P PPPPPPPP P P+PP P P +PPPP L PPPPP + S P
Sbjct: 1467 PQPQ----PPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPPPPPPAM------PSPPPPP 1516
Query: 750 KPAIEP 755
PA P
Sbjct: 1517 PPAAAP 1522
Score = 89.7 bits (221), Expect = 1e-17
Identities = 45/104 (43%), Positives = 50/104 (48%), Gaps = 6/104 (5%)
Query: 633 PMEGMASNQQKALPPPPASIPPPPPLPSGLGSLSPAPPMPPVSAGPPLPPPPP---PPPP 689
P+ G+ S P PP PPP P + P PP PP P LP PPP P P
Sbjct: 1435 PLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSPPPLVAPTPS 1494
Query: 690 LPPPSSAGPPPPPPPPPLPNSPAPPNPGGPPPAPPPPGLAPPPP 733
PPP P PPPPPP +P+ P PP P P A PP A P P
Sbjct: 1495 SPPPP---PLPPPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPSP 1535
Score = 80.5 bits (197), Expect = 9e-15
Identities = 57/157 (36%), Positives = 70/157 (44%), Gaps = 18/157 (11%)
Query: 609 KLNISSLSQLSPPNDHKDIHAALQPMEGMASNQQKALPPPPASIPPPPPLPSGLGSLSPA 668
K N+ +L S +D +D A + ++ S+ AL PP + P P G
Sbjct: 1371 KRNLETLPSFS--SDEEDSVAKNRDLQESISSAISALDDPPLAGPKDTSTPDG------- 1421
Query: 669 PPMPPVSAGPPLPPPPPPPPPLPPPSSAGPPPPP----PPPPLPNSPAPPNPGGPPPAPP 724
PP+ P +A P PPP P LP +S G P PP PPP P PAP PPP PP
Sbjct: 1422 PPLAPAAA----VPGPPPLPGLPSANSNGTPEPPLLEEKPPPTP-PPAPTPQPQPPPPPP 1476
Query: 725 PPGLAPPPPPGLFFGLGSSSSQCPRKPAIEPSCPMKP 761
PP A P PP L SS P P P+ P P
Sbjct: 1477 PPQPALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPP 1513
Score = 63.2 bits (152), Expect = 1e-09
Identities = 48/139 (34%), Positives = 54/139 (38%), Gaps = 34/139 (24%)
Query: 642 QKALPPPPASIPPPPPLPSGLGSLSPAPPMPPVSAGPPLPPPPP---------PPPPLPP 692
QK+ PPPP + P P GL + P +P V LPPPPP P P P
Sbjct: 761 QKSPPPPPPTAQSTQPTPHGLLLEAGGPDLPLV-----LPPPPPQLLPSVLSHAPSPSPS 815
Query: 693 PSSAG----------------PPPPPPPPPLP-NSPAPPNPGGPPPAPPPPGLAPP---P 732
S G PPPPPPPPP+P A G PA P P L P
Sbjct: 816 ASKVGVHLLEPATRDGAPQPPPPPPPPPPPMPLQLEAHLRSHGLEPAAPSPRLRPEESLD 875
Query: 733 PPGLFFGLGSSSSQCPRKP 751
PPG L + P P
Sbjct: 876 PPGAMQELLGALEPLPPAP 894
Score = 53.1 bits (126), Expect = 2e-06
Identities = 42/133 (31%), Positives = 52/133 (39%), Gaps = 13/133 (9%)
Query: 604 QLVPKKLNISSLSQLSPPNDHKDIHAALQPMEGMASNQQKALPPPPASIPPPPPLPSGLG 663
QL+P L S SP +H L+P + + A PPP PPPPP+P L
Sbjct: 800 QLLPSVL--SHAPSPSPSASKVGVHL-LEP-----ATRDGAPQPPPPPPPPPPPMPLQLE 851
Query: 664 SLSPAPPMPPVSAGPPLPPPPPPPPPLPPPSSAGPPPPPPPPPLPNSPAPPNPGGPPPA- 722
+ + + P + P L P PP G P PP P PPN G PA
Sbjct: 852 AHLRSHGLEPAAPSPRLRPEESLDPPGAMQELLGALEPLPPAPGDTGVGPPNSEGKDPAG 911
Query: 723 ----PPPPGLAPP 731
P P G P
Sbjct: 912 AYRSPSPQGTKAP 924
Score = 49.7 bits (117), Expect = 2e-05
Identities = 42/123 (34%), Positives = 46/123 (37%), Gaps = 17/123 (13%)
Query: 636 GMASNQQKALPPPPASIPP----PPPLPSGLGSLSPAPPMPPVSAGPPLPP---PPPPPP 688
G A + KA PP P PPP P P P AGP P P PP
Sbjct: 957 GAADDYGKAGPPEDEGDPKAGAGPPPGPPAYDPYGPYCPGRASGAGPETPGLGLDPNKPP 1016
Query: 689 PLPPPSSAGPPPPPPPPPLPNSPAPPNPGGPPPAPPPPGLAPPPPPGLFFGLGSSSSQCP 748
LP +A P P +P PP PP PPPP A P GL +S C
Sbjct: 1017 ELPSTVNAEPLGLIQSGPHQAAPPPP-----PPPPPPPAPASEPKGGL-----TSPIFCS 1066
Query: 749 RKP 751
KP
Sbjct: 1067 TKP 1069
Score = 49.3 bits (116), Expect = 2e-05
Identities = 31/99 (31%), Positives = 37/99 (37%), Gaps = 24/99 (24%)
Query: 617 QLSPPNDHKDIHAALQPMEGMASNQQKALPPPPASIPPPPPLPSGLGSLSPAPPMPPVSA 676
Q PP AL + + + PPPP PPPP +PS
Sbjct: 1468 QPQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPPPPPPAMPS---------------- 1511
Query: 677 GPPLPPPPPPPPPLPPPSSAGPPPPPPPPPLPNSPAPPN 715
PPPPPPP P +A PP P P P P P+
Sbjct: 1512 ------PPPPPPPAAAPLAA--PPEEPAAPSPEDPELPD 1542
Score = 47.0 bits (110), Expect = 1e-04
Identities = 31/103 (30%), Positives = 39/103 (37%), Gaps = 9/103 (8%)
Query: 620 PPNDHKDIHAALQPMEGMAS---------NQQKALPPPPASIPPPPPLPSGLGSLSPAPP 670
PP D D A P G + + P + P P L S A P
Sbjct: 967 PPEDEGDPKAGAGPPPGPPAYDPYGPYCPGRASGAGPETPGLGLDPNKPPELPSTVNAEP 1026
Query: 671 MPPVSAGPPLPPPPPPPPPLPPPSSAGPPPPPPPPPLPNSPAP 713
+ + +GP PPPPPPP PPP+ A P P+ S P
Sbjct: 1027 LGLIQSGPHQAAPPPPPPPPPPPAPASEPKGGLTSPIFCSTKP 1069
Score = 46.2 bits (108), Expect = 2e-04
Identities = 35/98 (35%), Positives = 37/98 (37%), Gaps = 29/98 (29%)
Query: 659 PSGLGSLSPAPPMPPVSAGPPLPPPPP----------------------PPPPLPPPSSA 696
P+GLG PA PP GPP PPPPP P L S A
Sbjct: 216 PAGLG---PAQT-PPYRPGPPDPPPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGA 271
Query: 697 GPPPPPPPPPLPNSPAPPNPGGPPPAPPPPGLAPPPPP 734
P PPPP LP P + PP PPPPP
Sbjct: 272 APGPPPPERALPRQDTVIKHYQRPASAQPP---PPPPP 306
Score = 46.2 bits (108), Expect = 2e-04
Identities = 35/92 (38%), Positives = 37/92 (40%), Gaps = 37/92 (40%)
Query: 677 GPPLPPPPPPPPPL-----PPPS----SAGPP------PPPPPPPLPN------SPAP-- 713
G L PPPPPP P P AG P PPPPP LP+ SP+P
Sbjct: 757 GAFLQKSPPPPPPTAQSTQPTPHGLLLEAGGPDLPLVLPPPPPQLLPSVLSHAPSPSPSA 816
Query: 714 -----------PNPGGPPPAPPPPGLAPPPPP 734
G P P PPPP PPPPP
Sbjct: 817 SKVGVHLLEPATRDGAPQPPPPPP---PPPPP 845
Score = 43.9 bits (102), Expect = 0.001
Identities = 30/78 (38%), Positives = 33/78 (42%), Gaps = 19/78 (24%)
Query: 646 PPPPASIPPPPPLPSGLGSL--SPAPPMPPVSAGPPL-------PPPPPPPPPLPP---- 692
P PP PPP LP+ L S A + P L P PPPP LP
Sbjct: 229 PGPPDPPPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGAAPGPPPPERALPRQDTV 288
Query: 693 ------PSSAGPPPPPPP 704
P+SA PPPPPPP
Sbjct: 289 IKHYQRPASAQPPPPPPP 306
Score = 41.2 bits (95), Expect = 0.006
Identities = 22/63 (34%), Positives = 27/63 (42%), Gaps = 2/63 (3%)
Query: 656 PPLPSGLGSLSPAPPMPPVSAGPPLPPPPPPPPPLPP--PSSAGPPPPPPPPPLPNSPAP 713
PP+P + P S+ PP P PPP P P +S PP P +P PAP
Sbjct: 1670 PPVPVRRSGQAKNPVSAGGSSAPPPKAPAPPPKPETPEKTTSEKPPEQTPETAMPEPPAP 1729
Query: 714 PNP 716
P
Sbjct: 1730 EKP 1732
Score = 40.8 bits (94), Expect = 0.008
Identities = 23/68 (33%), Positives = 26/68 (38%), Gaps = 5/68 (7%)
Query: 669 PPMPPVSAGPPLPPPPPPPPPLPPPSSAGPPPPPPPPPLPNSPAPPNPG-----GPPPAP 723
PP+P +G P PPP + PPP P P S PP PPAP
Sbjct: 1670 PPVPVRRSGQAKNPVSAGGSSAPPPKAPAPPPKPETPEKTTSEKPPEQTPETAMPEPPAP 1729
Query: 724 PPPGLAPP 731
P L P
Sbjct: 1730 EKPSLLRP 1737
Score = 39.7 bits (91), Expect = 0.017
Identities = 24/69 (34%), Positives = 26/69 (37%), Gaps = 8/69 (11%)
Query: 674 VSAGPPLPPPPPPP--------PPLPPPSSAGPPPPPPPPPLPNSPAPPNPGGPPPAPPP 725
V A P PP P P SSA PP P PPP P +P PP P
Sbjct: 1661 VCARKPWHRPPVPVRRSGQAKNPVSAGGSSAPPPKAPAPPPKPETPEKTTSEKPPEQTPE 1720
Query: 726 PGLAPPPPP 734
+ PP P
Sbjct: 1721 TAMPEPPAP 1729
Score = 37.0 bits (84), Expect = 0.11
Identities = 23/54 (42%), Positives = 27/54 (50%), Gaps = 4/54 (7%)
Query: 691 PPPSSAGPPPP-PPPPPLPNSPAPPNPGGPPPAPPPPGLAPPPPPGLFFGLGSS 743
PP AG PP PP +P P+ P G P P P + PPP G FGLG +
Sbjct: 1296 PPLYQAGLTPPLSPPKSVP--PSVPARGLQPQPPATPAVPHPPPSGA-FGLGGA 1346
Score = 35.8 bits (81), Expect = 0.25
Identities = 29/83 (34%), Positives = 30/83 (36%), Gaps = 6/83 (7%)
Query: 661 GLGSLSPAPPMPPVSAGPPLPPPPPPPPPLPPPSSAGPPPPPPPPPLPNSPAPPNPGGPP 720
G G P S GPP PP PPPP L S P L P PG
Sbjct: 462 GGGQAQDLSKAPSYSGGPPQPPSGPPPPGLATCQSYS--PDQLQGQLYGVQGEPYPG--- 516
Query: 721 PAPPPPGLAPPPPPGLFFGLGSS 743
PA GL P P L + G S
Sbjct: 517 PAAHSQGL-PTASPSLSYSTGHS 538
Score = 35.4 bits (80), Expect = 0.33
Identities = 20/60 (33%), Positives = 22/60 (36%)
Query: 669 PPMPPVSAGPPLPPPPPPPPPLPPPSSAGPPPPPPPPPLPNSPAPPNPGGPPPAPPPPGL 728
PP+ PPL PP PP +P PP P P P GG A GL
Sbjct: 1296 PPLYQAGLTPPLSPPKSVPPSVPARGLQPQPPATPAVPHPPPSGAFGLGGALEAAESEGL 1355
Score = 33.5 bits (75), Expect = 1.2
Identities = 38/117 (32%), Positives = 42/117 (35%), Gaps = 24/117 (20%)
Query: 659 PSGLGSLSPAPPMP-PVSAGPPLPPPPPPPPPLPPPSSAGPPPPPPPPPLPNS------- 710
P+ GS P P P S PP PP L P P P +P+S
Sbjct: 154 PASFGSR----PFPVPSSLSLQDPPFSPPANGLLSPHDVLHLKPSQAPTVPSSLGFERLA 209
Query: 711 ------PAPPNPGGPPPAPPPPGLAPPPP---PGLFFGLGSSSSQCPRKPAIEPSCP 758
PA P PP P P PPPP P F L SSS+ A E S P
Sbjct: 210 GGGVLGPAGLGPAQTPPYRPGPPDPPPPPRHLPTQFNLLASSSAAA---AAAEQSSP 263
Score = 32.7 bits (73), Expect = 2.1
Identities = 22/61 (36%), Positives = 24/61 (39%), Gaps = 5/61 (8%)
Query: 636 GMASNQQKA----LPPPPASIPPPPPLPSGLGSLSPAPPMPPVSAGPPLPPPPPPPPPLP 691
G A N A PPP A PPP P + + S PP P PP P P L
Sbjct: 1678 GQAKNPVSAGGSSAPPPKAPAPPPKP-ETPEKTTSEKPPEQTPETAMPEPPAPEKPSLLR 1736
Query: 692 P 692
P
Sbjct: 1737 P 1737
Score = 32.3 bits (72), Expect = 2.8
Identities = 44/164 (26%), Positives = 61/164 (37%), Gaps = 16/164 (9%)
Query: 607 PKKLNISS----LSQLSPP-NDHKDIHAALQPMEGMASNQQKALPPPPASIPPP--PPLP 659
PKKL +S L + PP K ++A E +++ KA P + P P L
Sbjct: 1069 PKKLLKTSSFHLLRRRDPPFQTPKKLYAQEYEFE---ADEDKADVPADIRLNPRRLPDLV 1125
Query: 660 SGLGSLSPAPPMPPVSAGPPLPPPPPPPPPLPPPSSA---GPPPPPPPPPLPNSPAPPNP 716
S S P+ + PP P P P P+ A GPP P P + P
Sbjct: 1126 SSCRSRPALSPLGDIDFCPPNPGPDGPRRRGRKPTKAKRDGPPRPRGRPRIRPLEVPTTA 1185
Query: 717 GGPPPAPPPPGLAPPPPPGLFFGLGSSSSQCPRKPAIEPSCPMK 760
G + P G P G G + + R +EP P+K
Sbjct: 1186 GPASASTPTDGAKKPRGRGRGRGRKAEEAGGTR---LEPLKPLK 1226
Score = 32.3 bits (72), Expect = 2.8
Identities = 22/67 (32%), Positives = 24/67 (35%), Gaps = 7/67 (10%)
Query: 646 PPPPASIPPPPPLPSGLGSLSPAPPMPPVSAGPPLPPPPPP-----PPPLPPPSSAGPPP 700
PP P P G S PP P A PP P P PP P ++ PP
Sbjct: 1670 PPVPVRRSGQAKNPVSAGGSSAPPPKAP--APPPKPETPEKTTSEKPPEQTPETAMPEPP 1727
Query: 701 PPPPPPL 707
P P L
Sbjct: 1728 APEKPSL 1734
Score = 32.0 bits (71), Expect = 3.6
Identities = 20/45 (44%), Positives = 22/45 (48%), Gaps = 3/45 (6%)
Query: 655 PPPLPSGLGS-LSPAPPMPPVSAGPPLPPPPPPPP--PLPPPSSA 696
PP +GL LSP +PP L P PP P P PPPS A
Sbjct: 1296 PPLYQAGLTPPLSPPKSVPPSVPARGLQPQPPATPAVPHPPPSGA 1340
Score = 30.8 bits (68), Expect = 8.1
Identities = 32/112 (28%), Positives = 38/112 (33%), Gaps = 21/112 (18%)
Query: 646 PPPPASIPPPPPLPSGLGSLSPAPPMPPVSA--GPPLPPPPPPPPPLPPPSSAGPPPPPP 703
PP P S PPPP L + S SP + G P P P LP S +
Sbjct: 479 PPQPPSGPPPPGLAT-CQSYSPDQLQGQLYGVQGEPYPGPAAHSQGLPTASPSLSYSTGH 537
Query: 704 PPPLPN-----SPAPPNPGG-------------PPPAPPPPGLAPPPPPGLF 737
P L P+ GG PP PPG+ P PG +
Sbjct: 538 SPALSGHGGGWGPSSLGGGGEASPSHIIRPLQSPPATGRPPGVGSPGAPGKY 589
>gi|4507909 Wiskott-Aldrich syndrome protein [Homo sapiens]
Length = 502
Score = 92.0 bits (227), Expect = 3e-18
Identities = 48/103 (46%), Positives = 50/103 (48%), Gaps = 17/103 (16%)
Query: 646 PPPPASIPPPPPLPSGLGSLSPAPPMPPVSAGPPLPPPPPPPPPLPPPSSAGPPPPPPPP 705
PPPP PPPP P G P PP PP + GPP+PPPPPPPPP PP S GP PPP PP
Sbjct: 359 PPPPGRGGPPPPPPPATGRSGPLPPPPPGAGGPPMPPPPPPPPP-PPSSGNGPAPPPLPP 417
Query: 706 PL-PNSPAPPNPG---------------GPPPAPPPPGLAPPP 732
L P P G P AP L PPP
Sbjct: 418 ALVPAGGLAPGGGRGALLDQIRQGIQLNKTPGAPESSALQPPP 460
Score = 89.0 bits (219), Expect = 2e-17
Identities = 54/150 (36%), Positives = 61/150 (40%), Gaps = 16/150 (10%)
Query: 620 PPNDHKDIHAALQPMEGMASNQQKALPPPPASIPPPPPLPSGLGSLSPAPPMPPVSAGPP 679
PP P+ G + LPP P I PPPP P G P PP GPP
Sbjct: 317 PPPSRGGNQLPRPPIVGGNKGRSGPLPPVPLGIAPPPPTPRG--------PPPPGRGGPP 368
Query: 680 LPPPPPP----PPPLPPPSSAGPP----PPPPPPPLPNSPAPPNPGGPPPAPPPPGLAPP 731
PPPP P P PPP + GPP PPPPPPP + P P PP P GLAP
Sbjct: 369 PPPPPATGRSGPLPPPPPGAGGPPMPPPPPPPPPPPSSGNGPAPPPLPPALVPAGGLAPG 428
Query: 732 PPPGLFFGLGSSSSQCPRKPAIEPSCPMKP 761
G Q + P S ++P
Sbjct: 429 GGRGALLDQIRQGIQLNKTPGAPESSALQP 458
Score = 83.6 bits (205), Expect = 1e-15
Identities = 60/164 (36%), Positives = 79/164 (48%), Gaps = 29/164 (17%)
Query: 614 SLSQLSPPNDHKDIHAALQPMEGMASNQQKALPPPPASIPPPPPLPSGLGSLSPAPPMPP 673
S +QL+ K I+ ++ G+ + +Q+ P +PPPPP PS G+ P PP+
Sbjct: 277 SEAQLTDAETSKLIYDFIEDQGGLEAVRQEMRRQEP--LPPPPP-PSRGGNQLPRPPIVG 333
Query: 674 VSAGPPLPPPPPPPPPLPPPSSAGP----------PPPPPPP------PLPNSPAPPNPG 717
+ G P PP P PPP + P PPPPPPP PLP P PP G
Sbjct: 334 GNKGRSGPLPPVPLGIAPPPPT--PRGPPPPGRGGPPPPPPPATGRSGPLP--PPPPGAG 389
Query: 718 GPPPAPPPPGLAPPPPPGLFFGLGSSSSQCPRKPAIEPSCPMKP 761
GPP PPPP PPPPP G+ + P PA+ P+ + P
Sbjct: 390 GPPMPPPPP--PPPPPP----SSGNGPAPPPLPPALVPAGGLAP 427
Score = 33.1 bits (74), Expect = 1.6
Identities = 24/84 (28%), Positives = 31/84 (36%), Gaps = 7/84 (8%)
Query: 627 IHAALQPMEGMASNQQKALPPPPASIPPP-----PPLPSGLGSLSPAPPMPPVSAGPPLP 681
+ +Q S ++ LPPPP PPLP G PP+ P+S G L
Sbjct: 141 VQEKIQKRNQRQSGDRRQLPPPPTPANEERRGGLPPLPLHPGGDQGGPPVGPLSLG--LA 198
Query: 682 PPPPPPPPLPPPSSAGPPPPPPPP 705
P + G P P P P
Sbjct: 199 TVDIQNPDITSSRYRGLPAPGPSP 222
>gi|210032580 SET domain containing 1B [Homo sapiens]
Length = 1923
Score = 88.6 bits (218), Expect = 3e-17
Identities = 46/93 (49%), Positives = 48/93 (51%), Gaps = 20/93 (21%)
Query: 645 LPPPPASIPPPPPLPSGLGSLSPAPPMPPVSAGPPLPPPPPPPPPLPPPSSAGPPPPPPP 704
LPPPP P PPP P P PP P PPLPPPPPPPPP P + PPP P P
Sbjct: 681 LPPPPGFPPLPPPPP-------PPPPQPGFPMPPPLPPPPPPPPPAHPAVTVPPPPLPAP 733
Query: 705 PPLPNSPAPPNPGGPPPAPPPPGLAPPPPPGLF 737
P +P PPP PP PP PPGLF
Sbjct: 734 PGVP----------PPPILPP---LPPFPPGLF 753
Score = 79.3 bits (194), Expect = 2e-14
Identities = 97/375 (25%), Positives = 135/375 (36%), Gaps = 55/375 (14%)
Query: 411 RPPRKGTTADTSELEALKRKMRHEKESLRAVFERSNSKPADGPSDSKSPDHSLTEQDDRT 470
R P + D+ E K + E+ES E + + D S D +E DD
Sbjct: 1021 RRPARPLELDSGGEEDEKESLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDESENDDED 1080
Query: 471 PGRLQAVWPPPKTKDTEEKVGLKYTEAEYQAAILHLKREHKEEIENLQAQFELRAFHIRG 530
+A D EE V + ++AE ++ E E E F
Sbjct: 1081 TALSEASEKDEGDSDEEETVSIVTSKAEATSS-----SESSESSE----------FESSS 1125
Query: 531 EHAMITARLEETIENLKHELEHRWRGGCEERKDVCISTDDDCPPKTFRNVCVQTDRETFL 590
E + ++ EE + + E E EE + V + P+ F Q E L
Sbjct: 1126 ESSPSSSEDEEEVVAREEEEEE------EEEEMVAEESMASAGPEDFE----QDGEEAAL 1175
Query: 591 KP-------CESESKTTRSNQLVPKKLNISSLSQLSPPNDHKDIHAALQPMEGMASNQQK 643
P E + + V + S L + P ++ + +P E +Q+
Sbjct: 1176 APGAPAVDSLGMEEEVDIETEAVAPEERPSMLDEPPLPVGVEEPADSREPPEEPGLSQEG 1235
Query: 644 AL---PPPPA-SIPPPPPL-----PSGLGSLSPAPPMP-PVSAGPPLPPPPPPPPPLPPP 693
A+ P PPA + PPL P + P PPM P+ PPLPPP PP PP PPP
Sbjct: 1236 AMLLSPEPPAKEVEARPPLSPERAPEHDLEVEPEPPMMLPLPLQPPLPPPRPPRPPSPPP 1295
Query: 694 ---SSAGPPPPPPPPPLPNSPAPPNPG---------GPPPAPPPPGLAPPPPPGLFFGLG 741
++ P PP PL P PG P PG PP G GL
Sbjct: 1296 EPETTDASHPSVPPEPLAEDHPPHTPGLCGSLAKSQSTETVPATPG-GEPPLSGGSSGLS 1354
Query: 742 SSSSQCPRKPAIEPS 756
SS Q P P P+
Sbjct: 1355 LSSPQVPGSPFSYPA 1369
Score = 50.4 bits (119), Expect = 1e-05
Identities = 39/124 (31%), Positives = 49/124 (39%), Gaps = 36/124 (29%)
Query: 647 PPPASIPPPPPLPSGLGSLSPAP-PMPPVSAGPPLPPPPP-----------PP------- 687
P P +P P LP+ L + + AP P+PP+ P PPP PP
Sbjct: 1432 PLPLPLPLPLALPAVLRAQARAPTPLPPLLPAPLASCPPPMKRKPGRPRRSPPSMLSLDG 1491
Query: 688 PPLPPPSSAG-------PPPPPPPPPLPNSPAPPN----------PGGPPPAPPPPGLAP 730
P + PP+ A P P P P++ P P PPP PP P P
Sbjct: 1492 PLVRPPAGAALGRELLLLPGQPQTPVFPSTHDPRTVTLDFRNAGIPAPPPPLPPQPPPPP 1551
Query: 731 PPPP 734
PPPP
Sbjct: 1552 PPPP 1555
Score = 50.1 bits (118), Expect = 1e-05
Identities = 40/125 (32%), Positives = 43/125 (34%), Gaps = 55/125 (44%)
Query: 645 LPPPPASIPPP------------------------PPLPSGLGS---LSPAPPMPPVSAG 677
LP P AS PPP PP + LG L P P PV
Sbjct: 1461 LPAPLASCPPPMKRKPGRPRRSPPSMLSLDGPLVRPPAGAALGRELLLLPGQPQTPVFPS 1520
Query: 678 PPLPPP----------PPPPPPLPPPSSAGPPPPPPPPPL--------------PNSPAP 713
P P PPPPLPP PPPPPPPPP+ P+ P
Sbjct: 1521 THDPRTVTLDFRNAGIPAPPPPLPPQ----PPPPPPPPPVEPTKLPFKELDNQWPSEAIP 1576
Query: 714 PNPGG 718
P P G
Sbjct: 1577 PGPRG 1581
Score = 47.0 bits (110), Expect = 1e-04
Identities = 33/96 (34%), Positives = 37/96 (38%), Gaps = 36/96 (37%)
Query: 667 PAPPMPPVSAGPPLPPPPPPPPPLPP------------PSSAGPPPPPP----------- 703
PAPP PP+ PP PPPPPPPPP+ P PS A PP P
Sbjct: 1537 PAPP-PPL---PPQPPPPPPPPPVEPTKLPFKELDNQWPSEAIPPGPRGRDEVTEEYMEL 1592
Query: 704 ---------PPPLPNSPAPPNPGGPPPAPPPPGLAP 730
PP + P G P +PP P P
Sbjct: 1593 AKSRGPWRRPPKKRHEDLVPPAGSPELSPPQPLFRP 1628
Score = 46.2 bits (108), Expect = 2e-04
Identities = 39/124 (31%), Positives = 45/124 (36%), Gaps = 29/124 (23%)
Query: 647 PPPASIPPPPPLPSGLGSLSPAPPMPPVSAGPPLPPPP-----------------PPPPP 689
PPPA P P S +P PV+ PP P P P PPP
Sbjct: 382 PPPAQATPAPGFKSAF-----SPYQTPVAHFPPPPEEPTATAAFGARDSGEFRRAPAPPP 436
Query: 690 LPP--PSSAGPPPPPPPPPLPNSPAPPNPGGPPPAPPPPGLAPPPPPGLFFGLGSSSSQC 747
LPP P + P PP PP P++ + G P P P P L SS
Sbjct: 437 LPPAEPLAKEKPGTPPGPPPPDTNSMELGGRPTFGWSPEPCDSPGTPTL-----ESSPAG 491
Query: 748 PRKP 751
P KP
Sbjct: 492 PEKP 495
Score = 46.2 bits (108), Expect = 2e-04
Identities = 45/146 (30%), Positives = 49/146 (33%), Gaps = 60/146 (41%)
Query: 647 PPPASIPPPPPLPSGLGSLSPAPPMPPVSAGPPLPPPP--PPPPPLPP------------ 692
PPP PPPPP P+ P PP+P A P +PPPP PP PP PP
Sbjct: 706 PPPLPPPPPPPPPAHPAVTVPPPPLP---APPGVPPPPILPPLPPFPPGLFPVMQVDMSH 762
Query: 693 ---------PSS----------------AGPPPP-----------------PPPPPLPNS 710
P S A P PP PP P S
Sbjct: 763 VLGGQWGGMPMSFQMQTQVLSRLMTGQGACPYPPFMAAAAAAASAGLQFVNLPPYRGPFS 822
Query: 711 PAPPNPGGPPPAPPPPGLAPP-PPPG 735
+ PG PP P P PPPG
Sbjct: 823 LSNSGPGRGQHWPPLPKFDPSVPPPG 848
Score = 42.4 bits (98), Expect = 0.003
Identities = 41/125 (32%), Positives = 49/125 (39%), Gaps = 24/125 (19%)
Query: 654 PPPPLPSGLGSLSPAPPMPPV--SAGPPLPPPPPPPPPLPPPS--SAGPPPPPPPPPL-- 707
P PLP+G P PV G PLP P P P PL P+ A P P PPL
Sbjct: 1403 PVCPLPTGRRDERSGPLASPVLLETGLPLPLPLPLPLPLALPAVLRAQARAPTPLPPLLP 1462
Query: 708 -PNSPAPP----NPGGPPPAPPP----PGLAPPPPPGLFFGLGSSSSQCPRKPAIEPSCP 758
P + PP PG P +PP G PP G G R+ + P P
Sbjct: 1463 APLASCPPPMKRKPGRPRRSPPSMLSLDGPLVRPPAGAALG---------RELLLLPGQP 1513
Query: 759 MKPLY 763
P++
Sbjct: 1514 QTPVF 1518
Score = 40.8 bits (94), Expect = 0.008
Identities = 40/136 (29%), Positives = 45/136 (33%), Gaps = 34/136 (25%)
Query: 660 SGLGSLSPAPPMPPVSAGPPLPPPPPPPPPLP----------PPSSAGPPPP-------- 701
+G S P P SA PPP P P P + PPPP
Sbjct: 360 TGGSSGPPFKAQPQDSATFAHTPPPAQATPAPGFKSAFSPYQTPVAHFPPPPEEPTATAA 419
Query: 702 ------------PPPPPLPNS-PAPPNPGGPPPAPPPPGLAPPPPPGL-FFGLGSSSSQC 747
P PPPLP + P G PP PPPP G FG
Sbjct: 420 FGARDSGEFRRAPAPPPLPPAEPLAKEKPGTPPGPPPPDTNSMELGGRPTFGWSPEPCDS 479
Query: 748 PRKPAIE--PSCPMKP 761
P P +E P+ P KP
Sbjct: 480 PGTPTLESSPAGPEKP 495
Score = 35.4 bits (80), Expect = 0.33
Identities = 31/82 (37%), Positives = 34/82 (41%), Gaps = 9/82 (10%)
Query: 657 PLPSGLGSLSPAPPMPPVSAGPPLPPPPPPPPPLPPPSSAGPPPPPPPPPLPNSPAPP-- 714
P+ S LSP P S P P PP PSS G P P LP+S
Sbjct: 532 PISSSSSQLSPLAPFGTNSQ----PGFRGPTPPSSRPSSTGLEDISPTP-LPDSDEDEEL 586
Query: 715 NPGGPPPAPPPPGLAPPPPPGL 736
+ G P PP PG PP P GL
Sbjct: 587 DLGLGPRPPPEPG--PPDPAGL 606
Score = 32.7 bits (73), Expect = 2.1
Identities = 29/90 (32%), Positives = 32/90 (35%), Gaps = 28/90 (31%)
Query: 644 ALPPPPASIPPPPPLP----------SGLGSLSPAPPMPP----------------VSAG 677
A PPP PPPPP P L + P+ +PP S G
Sbjct: 1538 APPPPLPPQPPPPPPPPPVEPTKLPFKELDNQWPSEAIPPGPRGRDEVTEEYMELAKSRG 1597
Query: 678 PPLPPPPPPPPPLPPPSSAGPPPPPPPPPL 707
P PP L PP AG P PP PL
Sbjct: 1598 PWRRPPKKRHEDLVPP--AGSPELSPPQPL 1625
Score = 32.7 bits (73), Expect = 2.1
Identities = 26/88 (29%), Positives = 32/88 (36%), Gaps = 22/88 (25%)
Query: 645 LPPPPASIPPPPPLP------SGLGSLSPAPPMPP----------------VSAGPPLPP 682
LPP P PPPPP+ L + P+ +PP S GP P
Sbjct: 1543 LPPQPPPPPPPPPVEPTKLPFKELDNQWPSEAIPPGPRGRDEVTEEYMELAKSRGPWRRP 1602
Query: 683 PPPPPPPLPPPSSAGPPPPPPPPPLPNS 710
P L PP+ + PP P P S
Sbjct: 1603 PKKRHEDLVPPAGSPELSPPQPLFRPRS 1630
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 88.2 bits (217), Expect = 4e-17
Identities = 67/183 (36%), Positives = 76/183 (41%), Gaps = 21/183 (11%)
Query: 619 SPPNDHKDIHAALQPMEGMASNQQKALPP---PPASIPPPPPL-PSGLGSLSPAPPMPPV 674
SPP A P+ A+ +A P PP +PP PP P S +P P PP
Sbjct: 670 SPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPP 729
Query: 675 SAGPPLPPPPPP-----------PPPLPPPSSAGPP---PPPPPPPLPNSP-APPNPGGP 719
A PPL PP P PPP PP A PP PP PP LP SP A P P P
Sbjct: 730 LAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAP 789
Query: 720 PPAPPPPGLAPPPPPGLFFGLG--SSSSQCPRKPAIEPSCPMKPLYWTRIQISDRSQNAT 777
P PP A P PP F G S S+ P P P P+ + S A+
Sbjct: 790 PALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPAS 849
Query: 778 PTL 780
PTL
Sbjct: 850 PTL 852
Score = 77.0 bits (188), Expect = 1e-13
Identities = 74/210 (35%), Positives = 92/210 (43%), Gaps = 31/210 (14%)
Query: 612 ISSLSQLSPPNDHKDIHAALQPMEGMASNQQKALPPPPASI--PP--------PPPLPSG 661
+SSL+ SP + + P+E +S +L PPAS+ PP PPPL +
Sbjct: 492 LSSLASHSPQAPLSSL--IMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTA 549
Query: 662 LGSLS-PAPPMPPVSAGPPLPPPPPP---PPPLPPPSSAGPPPPPPP----PPLPNSPAP 713
L+ P PP A PL PP P PPP P S A PPP PP PPL P+P
Sbjct: 550 SAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSP 609
Query: 714 P-NPGGPPP--APP----PPGLAPPPPPGL--FFGLGSSSSQCPRKPAIE-PSCPMKPLY 763
P +P PP APP PP APP PP L + S Q P A+ P P
Sbjct: 610 PLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPP 669
Query: 764 WTRIQISDRSQNATPTLWDSLEEPDIRDPS 793
+Q + S A+P + S P PS
Sbjct: 670 SPPVQ-APFSPPASPPVSPSATPPSQAPPS 698
Score = 75.1 bits (183), Expect = 4e-13
Identities = 48/118 (40%), Positives = 54/118 (45%), Gaps = 6/118 (5%)
Query: 646 PPPPASIP-PPPPLPSGLGSLSPAPPMPPVSAGPPLPPPPPPPPPLPPPSSAGPPPPPPP 704
P PP P PP P S +P PP A PPL PP PP PP S + PPP P
Sbjct: 669 PSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPAS-PPMSPSATPPPQAP 727
Query: 705 PPLPNSPAPPNPGGPPPAPPPPGLAPPPPPGLFFGLGSSSSQCPRKPAIEPSCPMKPL 762
PPL P P PPA PP + PPP + L + Q P P+ S PM PL
Sbjct: 728 PPLAAPPLQVPPS--PPASPPMSPSATPPPRVPPLLAAPPLQVP--PSPPASLPMSPL 781
Score = 68.9 bits (167), Expect = 3e-11
Identities = 51/165 (30%), Positives = 62/165 (37%), Gaps = 45/165 (27%)
Query: 616 SQLSPPNDHKDIHAALQPMEGMASNQQKALPP---PPASIPPPPPL-PSGLGSLSPAPPM 671
S +PP A PM A+ +A PP PP +PP PP P S +P P +
Sbjct: 698 SLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRV 757
Query: 672 PPVSAGPPLPPPPPPP-----------PPLPPPSSAGPP--------------------- 699
PP+ A PPL PP PP PP PP+ A PP
Sbjct: 758 PPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSA 817
Query: 700 ---------PPPPPPPLPNSPAPPNPGGPPPAPPPPGLAPPPPPG 735
PPP PP+ +P P PP +P PP PG
Sbjct: 818 SLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPG 862
Score = 68.6 bits (166), Expect = 3e-11
Identities = 52/167 (31%), Positives = 65/167 (38%), Gaps = 40/167 (23%)
Query: 625 KDIHAALQPMEGMASNQQKALPPPPASIPPPPPLPSGLGSLSP----------APPMPPV 674
+ + ++ P+ A + A P A P P P GL +L P AP + P+
Sbjct: 240 RSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPL 299
Query: 675 SAGP------------PLPPPP----------PPPPPLPPPSSAGPPPPPPPP---PLPN 709
S+ P P+PPP PP PPL P PP P PP LP+
Sbjct: 300 SSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPS 359
Query: 710 SPAPPNPGGPPPAPPPPGLAPP-----PPPGLFFGLGSSSSQCPRKP 751
PA P PP PP APP PP + L S S Q P P
Sbjct: 360 PPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSP 406
Score = 65.1 bits (157), Expect = 4e-10
Identities = 47/141 (33%), Positives = 63/141 (44%), Gaps = 31/141 (21%)
Query: 603 NQLVPKKLNISSLSQLSPPNDHKDIHAALQPMEGM-------ASNQQKALPPP------- 648
+Q PK L Q++PP KD AL P+ + + + +PPP
Sbjct: 270 SQPKPKGLQALRPPQVTPPR--KDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPL 327
Query: 649 PASIPPPPPLPSGLGSLSPAPPMPPVSAGPPLPPPPPPPPPLPPPSSAGPPPPPPP---- 704
PA++PP PPL + L P+P PP + LP PP PP PPS PP PP
Sbjct: 328 PATLPPSPPLATPLPLAPPSPSAPP--SLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQT 385
Query: 705 -PPL--------PNSPAPPNP 716
PP+ P+ APP+P
Sbjct: 386 IPPIQVPHSLTSPSLQAPPSP 406
Score = 63.9 bits (154), Expect = 9e-10
Identities = 46/122 (37%), Positives = 54/122 (44%), Gaps = 20/122 (16%)
Query: 644 ALPPPPASIPPPPPLPSGLGS----LSPAP----PMPPVSAGPPLPPPPPPPPPL----- 690
A PP S PPP +P L + + P+P PM P++ PP PP PPL
Sbjct: 743 ASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPS 802
Query: 691 PPPSSAGPPPPPPPPPLPNSP-APPNPGGPPPAPPPPGLAPPPPPGLFFGLGSSSSQCPR 749
PP S G P P LP SP A P P PP P PP PP S + Q PR
Sbjct: 803 PPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPP------ASPTLQAPR 856
Query: 750 KP 751
+P
Sbjct: 857 RP 858
Score = 55.8 bits (133), Expect = 2e-07
Identities = 53/174 (30%), Positives = 64/174 (36%), Gaps = 41/174 (23%)
Query: 632 QPMEGMASNQQKALPPPPASIPPPPPL-PSGLGSLSPA----PPMPPVSAGPPLPPPPPP 686
Q +A+ +ALP PPAS P P PS +SP P PPV A P L PP P
Sbjct: 787 QAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSP 846
Query: 687 P----------PPLPPPSSAGPPP-------PPPPPPLPNSPA-----PPNPGGPPPAPP 724
P PP P P ++ P P PPPP SP+ P G A
Sbjct: 847 PASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATS 906
Query: 725 PP--------------GLAPPPPPGLFFGLGSSSSQCPRKPAIEPSCPMKPLYW 764
P +PPP L ++ S+ P P P PL W
Sbjct: 907 TPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPW 960
Score = 49.7 bits (117), Expect = 2e-05
Identities = 63/223 (28%), Positives = 81/223 (36%), Gaps = 59/223 (26%)
Query: 597 SKTTRSNQLVPKKLNISSLSQL----SPPNDHKDIHAALQPMEGMASNQQKALP------ 646
S T+ S Q P L +SSL SP + P + AS + P
Sbjct: 394 SLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPD 453
Query: 647 -PP---PASIPPPPPLPSGLG-------------------SLSPAPPMPPVSAGPPLPPP 683
PP P S+P PPL + L SL+ P P+S+ + PP
Sbjct: 454 SPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSS--LIMPP 511
Query: 684 PPPPPPLPPPSSAGPP-----------PPPPPPPLPNSPAP---PNPGGPPPAPPPPGLA 729
L PPS PP P PPPL + AP P+ PP P P A
Sbjct: 512 LETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQA 571
Query: 730 PP-----PPPGLFFGLGSSSSQCP---RKPAIE--PSCPMKPL 762
PP PPP + + Q P P ++ PS P+ PL
Sbjct: 572 PPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPL 614
Score = 41.6 bits (96), Expect = 0.005
Identities = 39/127 (30%), Positives = 45/127 (35%), Gaps = 23/127 (18%)
Query: 653 PPPPPLPSGLGSLSPAPPMPPVSAGPPLPPPPPPPPPLPPPSSAGPPPPPPP-------- 704
P L S LS P + G P P P P + PP PP
Sbjct: 237 PASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPAL 296
Query: 705 PPLPNSP-APPNPGG------PPP---APPPPGLAPPPPPGLFFGLGSSSSQCPRKPAIE 754
PL +SP A P+P G PPP A P P PP PP L + P P+
Sbjct: 297 GPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPP-----LATPLPLAPPSPSAP 351
Query: 755 PSCPMKP 761
PS P
Sbjct: 352 PSLQTLP 358
Score = 40.8 bits (94), Expect = 0.008
Identities = 56/238 (23%), Positives = 75/238 (31%), Gaps = 58/238 (24%)
Query: 600 TRSNQLVPKKLNISSLSQLSPPNDHKDIHAALQPMEGMASNQQKALPPPPASIPPPPPLP 659
T++ + P + L PP+ L P A + LP PPA+ P P
Sbjct: 312 TKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAP-- 369
Query: 660 SGLGSLSPAPPMPPVSAGPPLP--PPPPPPPPLPPPSSAGPPPPPPPPPL---------- 707
P+ PP+ A P L PP P L PS PP P L
Sbjct: 370 -------PSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPT 422
Query: 708 ---------------------PNSPAPPNPGGPP-------PAPPP------PGLAPPPP 733
P+ PA P PP PA PP P ++P
Sbjct: 423 LQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSS 482
Query: 734 PGLFFGLGSSSSQCPRKPAIEPSCPMKPLYWTRIQISDRSQNATPTLWDSLEEPDIRD 791
P L + SS P S + P T+ ++ S P SL P + +
Sbjct: 483 PLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPA---SLTTPPLEN 537
Score = 37.7 bits (86), Expect = 0.066
Identities = 34/101 (33%), Positives = 40/101 (39%), Gaps = 9/101 (8%)
Query: 659 PSGLGSLSPAPPMPPVSAGPPLPPPPPPPPPLPPPSSAGPPPPPPPPPLPNSP----APP 714
P G + SP PP ++A P P PPL + G P P PP P S
Sbjct: 918 PEGGAAASP-PPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIY 976
Query: 715 NPGGPPPAPPPPG-LAPPPPPGLFFG---LGSSSSQCPRKP 751
GP A P PG L P P PG G G+ + R P
Sbjct: 977 ETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSP 1017
Score = 33.5 bits (75), Expect = 1.2
Identities = 29/93 (31%), Positives = 35/93 (37%), Gaps = 12/93 (12%)
Query: 646 PPPPASIPPPPPL-PSGLGSLSPA-----PPMPPVSAGPPLPPPPPPPPPLPPPSSAGPP 699
P PP S PPPP+ P+ L L A P+ + G P P P SAG
Sbjct: 27 PRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAGTS 86
Query: 700 PPPPPPPLPNSPAPPNPGGPPPAPPPPGLAPPP 732
P + PP G APP +P P
Sbjct: 87 SRNP------ASRPPASGRGERAPPAKNTSPGP 113
Score = 31.2 bits (69), Expect = 6.2
Identities = 29/106 (27%), Positives = 32/106 (30%), Gaps = 23/106 (21%)
Query: 657 PLPSGLGSLSPAPPMPPVSAGPPLPPPPPPPPPLPPPSSAGPP----------------- 699
P G L+P PP G P PPPP P L +AG
Sbjct: 17 PAARAPGLLTPRPP------GSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATI 70
Query: 700 PPPPPPPLPNSPAPPNPGGPPPAPPPPGLAPPPPPGLFFGLGSSSS 745
P P P A + P PP G PP G SS
Sbjct: 71 PESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSS 116
>gi|23592228 extraembryonic, spermatogenesis, homeobox 1-like [Homo
sapiens]
Length = 406
Score = 87.4 bits (215), Expect = 7e-17
Identities = 48/111 (43%), Positives = 57/111 (51%), Gaps = 7/111 (6%)
Query: 629 AALQPMEGMASNQQKALPPPPASIPPPPPLPSGLGSLSPAPPMPPVSAGPPLPPPPPPPP 688
A + PM + + A PP + P PP P + + P PPM PV GPP+ P PP PP
Sbjct: 268 APMPPMAPVPPGSRMAPVPPGPRMAPVPPWPP-MAPVPPWPPMAPVPTGPPMAPVPPGPP 326
Query: 689 ----PLPPPSSAGPPPPPPPPPLPNSPAPPNPGGPPPAPPPPG--LAPPPP 733
P PP + PP PP P P P P P GPP AP PPG +AP PP
Sbjct: 327 MARVPPGPPMARVPPGPPMAPLPPGPPMAPLPPGPPMAPLPPGPPMAPLPP 377
Score = 80.5 bits (197), Expect = 9e-15
Identities = 49/126 (38%), Positives = 58/126 (46%), Gaps = 16/126 (12%)
Query: 647 PPPASIPPPPPLPSGLGSLSPAPPMPPVSAGPPLPPPPPPP--PPLPPPSSAGPPPPPPP 704
PP +PP PP P + P PP PP++ PP+ P PP P+PP P PP PP
Sbjct: 244 PPVLPVPPMPPRPP----MVPMPPRPPIAPMPPMAPVPPGSRMAPVPPGPRMAPVPPWPP 299
Query: 705 ----PPLPNSPAPPNPGGPPPAPPPPG----LAPPPPPGLFFGLGSSSSQCPRKPAIEPS 756
PP P P P P GPP AP PPG PP PP G + P P + P
Sbjct: 300 MAPVPPWP--PMAPVPTGPPMAPVPPGPPMARVPPGPPMARVPPGPPMAPLPPGPPMAPL 357
Query: 757 CPMKPL 762
P P+
Sbjct: 358 PPGPPM 363
Score = 79.7 bits (195), Expect = 2e-14
Identities = 50/126 (39%), Positives = 59/126 (46%), Gaps = 25/126 (19%)
Query: 647 PPPASIPPPPPLPSG--LGSLSPAPPMPPVSAGPPLPPPPPPPPPLPPPSSAGPPPPPPP 704
PP A +PP P+P G + + P P M PV PP+ P PP PP P P+ GPP P P
Sbjct: 265 PPIAPMPPMAPVPPGSRMAPVPPGPRMAPVPPWPPMAPVPPWPPMAPVPT--GPPMAPVP 322
Query: 705 PPLPNSPAPPN------PGGPPPAPPPPG--LAPPPPPGLFFGLGSSSSQCPRKPAIEPS 756
P P + PP P GPP AP PPG +AP PP P + P
Sbjct: 323 PGPPMARVPPGPPMARVPPGPPMAPLPPGPPMAPLPPG-------------PPMAPLPPG 369
Query: 757 CPMKPL 762
PM PL
Sbjct: 370 PPMAPL 375
Score = 77.4 bits (189), Expect = 8e-14
Identities = 49/126 (38%), Positives = 59/126 (46%), Gaps = 13/126 (10%)
Query: 645 LPPPPASIPPPPPLPSGLGSLSPAPPMPPVSAGPPLPPPPPPP--PPLPP-PSSAGPPPP 701
+PP P +P PP P ++P PPM PV G + P PP P P+PP P A PP
Sbjct: 252 MPPRPPMVPMPPRPP-----IAPMPPMAPVPPGSRMAPVPPGPRMAPVPPWPPMAPVPPW 306
Query: 702 PPPPPLPNS-PAPPNPGGPPPAPPPPG----LAPPPPPGLFFGLGSSSSQCPRKPAIEPS 756
PP P+P P P P GPP A PPG PP PP G + P P + P
Sbjct: 307 PPMAPVPTGPPMAPVPPGPPMARVPPGPPMARVPPGPPMAPLPPGPPMAPLPPGPPMAPL 366
Query: 757 CPMKPL 762
P P+
Sbjct: 367 PPGPPM 372
Score = 75.1 bits (183), Expect = 4e-13
Identities = 46/98 (46%), Positives = 53/98 (54%), Gaps = 21/98 (21%)
Query: 647 PPPASIPPPPPL---PSG--LGSLSPAPPMPPVSAGPPLP--PPPPPPPPLPPPSSAGPP 699
PP A +PP PP+ P+G + + P PPM V GPP+ PP PP PLPP GPP
Sbjct: 298 PPMAPVPPWPPMAPVPTGPPMAPVPPGPPMARVPPGPPMARVPPGPPMAPLPP----GPP 353
Query: 700 PPPPPPPLPNSPAPPNPGGPPPAPPPP-------GLAP 730
P PP P +P PP GPP AP PP GLAP
Sbjct: 354 MAPLPPGPPMAPLPP---GPPMAPLPPRSHVPHTGLAP 388
Score = 53.5 bits (127), Expect = 1e-06
Identities = 34/80 (42%), Positives = 39/80 (48%), Gaps = 13/80 (16%)
Query: 663 GSLSPAPPMPP---VSAGPPLPPPPP-PPPPLPPPSSAGPPPPPPPPPLPNSPAPPNPGG 718
G+ AP + P V P LP PP P PP+PP PP P PP P +P PP
Sbjct: 221 GAYYAAPALDPALCVHLVPQLPRPPVLPVPPMPPR----PPMVPMPPRPPIAPMPPMAPV 276
Query: 719 PP-----PAPPPPGLAPPPP 733
PP P PP P +AP PP
Sbjct: 277 PPGSRMAPVPPGPRMAPVPP 296
Score = 44.7 bits (104), Expect = 5e-04
Identities = 27/67 (40%), Positives = 34/67 (50%), Gaps = 4/67 (5%)
Query: 647 PPPASIPPPPP---LPSGLGSLSPAPPMPPVSAGPPLPPPPPPPPPLPPPSSAGPPPPPP 703
PP A +PP PP LP G ++P PP PP++ PP PP P PP P + P
Sbjct: 334 PPMARVPPGPPMAPLPPG-PPMAPLPPGPPMAPLPPGPPMAPLPPRSHVPHTGLAPVHIT 392
Query: 704 PPPLPNS 710
P+ NS
Sbjct: 393 WAPVINS 399
>gi|7706501 WW domain binding protein 11 [Homo sapiens]
Length = 641
Score = 87.4 bits (215), Expect = 7e-17
Identities = 58/117 (49%), Positives = 63/117 (53%), Gaps = 21/117 (17%)
Query: 638 ASNQQKALPP--PPASIPPPP-PLPSGLGSLSPAPPMPPVSAGPP--LPPPPPP--PPPL 690
AS+QQ+A P PP+ I PP P P LG PAPP+ P GPP LPP PPP PP L
Sbjct: 386 ASSQQQAPPQSVPPSQIQAPPMPGPPPLGP-PPAPPLRP--PGPPTGLPPGPPPGAPPFL 442
Query: 691 PPPSSAG----------PPPPPPPPPLPNSPAPPN-PGGPPPAPPPPGLAPPPPPGL 736
PP G P PPP PP P PP P GPPP PPP L PP PPG+
Sbjct: 443 RPPGMPGLRGPLPRLLPPGPPPGRPPGPPPGPPPGLPPGPPPRGPPPRLPPPAPPGI 499
Score = 82.8 bits (203), Expect = 2e-15
Identities = 58/164 (35%), Positives = 66/164 (40%), Gaps = 27/164 (16%)
Query: 594 ESESKTTRSNQLVPKKLNISSLSQLSPPNDHKDIHAALQPMEGMASNQQKALPP-----P 648
E +S+ + + +S Q +PP PM G PP P
Sbjct: 367 EKQSQKQHKEESHSDGTSTASSQQQAPPQSVPPSQIQAPPMPGPPPLGPPPAPPLRPPGP 426
Query: 649 PASIPPPPP-----------LPSGLGSLSPAPPMPPVSAGPPLPPPPPPP--PPLPPPSS 695
P +PP PP +P G L P P PP PPP PPP PP PPP
Sbjct: 427 PTGLPPGPPPGAPPFLRPPGMPGLRGPLPRLLPPGPPPGRPPGPPPGPPPGLPPGPPP-- 484
Query: 696 AGPPPPPPPPPLPNSPAPPNPG------GPPPAPPPPGLAPPPP 733
GPPP PPP P P PP PG PP P PPGL PP P
Sbjct: 485 RGPPPRLPPPAPPGIP-PPRPGMMRPPLVPPLGPAPPGLFPPAP 527
Score = 67.8 bits (164), Expect = 6e-11
Identities = 49/122 (40%), Positives = 54/122 (44%), Gaps = 23/122 (18%)
Query: 620 PPNDHKDIHAALQP--MEGMASNQQKALPP--PPASIPPPPPLPSGLGSLSPAPPMPPVS 675
PP L+P M G+ + LPP PP P PPP P P +PP
Sbjct: 431 PPGPPPGAPPFLRPPGMPGLRGPLPRLLPPGPPPGRPPGPPP--------GPPPGLPP-- 480
Query: 676 AGPPLPPPPPPPPPLPPPSSAGPPPPPP---PPPL--PNSPAPPNPGGPPPAPPPPGLAP 730
PP PPP PPP PP G PPP P PPL P PAPP P P P P L+
Sbjct: 481 GPPPRGPPPRLPPPAPP----GIPPPRPGMMRPPLVPPLGPAPPGLFPPAPLPNPGVLSA 536
Query: 731 PP 732
PP
Sbjct: 537 PP 538
Score = 44.3 bits (103), Expect = 7e-04
Identities = 28/69 (40%), Positives = 29/69 (42%), Gaps = 10/69 (14%)
Query: 647 PPPASIPP--PPPLPSGLGSLSPAPPMPPVSAGPPLPPPPPPPPP--LPPPSSAGPPPPP 702
PPP PP PPP P G+ PP P PPL PP P PP PP P
Sbjct: 482 PPPRGPPPRLPPPAPPGI------PPPRPGMMRPPLVPPLGPAPPGLFPPAPLPNPGVLS 535
Query: 703 PPPPLPNSP 711
PP L P
Sbjct: 536 APPNLIQRP 544
Score = 38.5 bits (88), Expect = 0.039
Identities = 24/70 (34%), Positives = 29/70 (41%), Gaps = 10/70 (14%)
Query: 667 PAPPMPPVSAG---PPLPPPPPPPPPLPPPSSAGPPP-------PPPPPPLPNSPAPPNP 716
P P MP + +P P PP + +SA PP P +P P P
Sbjct: 140 PLPDMPHAPSNILIQDIPLPGAQPPSILKKTSAYGPPTRAVSILPLLGHGVPRLPPGRKP 199
Query: 717 GGPPPAPPPP 726
GPPP PPPP
Sbjct: 200 PGPPPGPPPP 209
Score = 38.5 bits (88), Expect = 0.039
Identities = 24/54 (44%), Positives = 24/54 (44%), Gaps = 16/54 (29%)
Query: 687 PPPLPPPSSAGPPPPPPPPPLPNSPAPPNPGGPPPAPPPPGLAPPPPPGLFFGL 740
PP PPS PP P PPPL GPPPAPP PPG GL
Sbjct: 393 PPQSVPPSQIQAPPMPGPPPL----------GPPPAPP------LRPPGPPTGL 430
Score = 31.6 bits (70), Expect = 4.7
Identities = 16/35 (45%), Positives = 16/35 (45%)
Query: 654 PPPPLPSGLGSLSPAPPMPPVSAGPPLPPPPPPPP 688
PP S L L P P PP PPP PPPP
Sbjct: 175 PPTRAVSILPLLGHGVPRLPPGRKPPGPPPGPPPP 209
>gi|150417989 cyclin K isoform 1 [Homo sapiens]
Length = 580
Score = 87.0 bits (214), Expect = 9e-17
Identities = 55/130 (42%), Positives = 64/130 (49%), Gaps = 27/130 (20%)
Query: 628 HAALQPMEGMASNQQKALPP---PPASIP----------PPPPLPSGLGSLSPAPPMPPV 674
+ +LQ M ALPP PPA +P PPPP+P S P P +PP
Sbjct: 444 YQSLQSMMKTEGPSYGALPPAYGPPAHLPYHPHVYPPNPPPPPVPPPPASFPP-PAIPPP 502
Query: 675 SAGPPLPPPP-----PPPPPLPPPSSAGPPPPPPPPPLPNSPAPP---NPGGPPPAPPPP 726
+ G P PPP PPPPP PP+ A PP PPP LP + PP PGG PP PP
Sbjct: 503 TPGYPPPPPTYNPNFPPPPPRLPPTHAVPPHPPPGLGLPPASYPPPAVPPGGQPPVPP-- 560
Query: 727 GLAPPPPPGL 736
P PPPG+
Sbjct: 561 ---PIPPPGM 567
Score = 78.6 bits (192), Expect = 3e-14
Identities = 56/143 (39%), Positives = 62/143 (43%), Gaps = 41/143 (28%)
Query: 646 PPPPASIPPPPPLPSGLGSLS----------------------PAPPMPPVSAGPPL--- 680
PPP PPPPP S + +S P+ P + GPP
Sbjct: 413 PPPLPHRPPPPPPSSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSYGALPPAYGPPAHLP 472
Query: 681 ------PPPPPPPPPLPPPSSAGPPPPPPPPPLPNSPAPP---NPGGPPPAP--PPPGLA 729
PP PPPPP PPP+S PPP PPP P P PP NP PPP P PP
Sbjct: 473 YHPHVYPPNPPPPPVPPPPASF--PPPAIPPPTPGYPPPPPTYNPNFPPPPPRLPPTHAV 530
Query: 730 PP-PPPGLFFGLGSSSSQCPRKP 751
PP PPPGL GL +S P P
Sbjct: 531 PPHPPPGL--GLPPASYPPPAVP 551
Score = 58.5 bits (140), Expect = 4e-08
Identities = 47/152 (30%), Positives = 61/152 (40%), Gaps = 24/152 (15%)
Query: 613 SSLSQLSPPNDHKDIHAALQPMEGMASNQQKALPPPPASIPPPP----------PLPSGL 662
S SQ S P+ + P + Q P P+ P P P
Sbjct: 291 SQPSQSSEPSQPQQ----KDPQQPAQQQQPAQQPKKPSPQPSSPRQVKRAVVVSPKEENK 346
Query: 663 GSLSPAPPMPPV-SAGPPLPPPPPPPPPLPPPSS----AGPPPPPPPPPLPNSPAPPNPG 717
+ P P +P + + PPLPP PPP PP ++ A PP P LP PP P
Sbjct: 347 AAEPPPPKIPKIETTHPPLPPAHPPPDRKPPLAAALGEAEPPGPVDATDLPKVQIPP-PA 405
Query: 718 GPPPA---PPPPGLAPPPPPGLFF-GLGSSSS 745
P P PP P PPPPP + G+ ++SS
Sbjct: 406 HPAPVHQPPPLPHRPPPPPPSSYMTGMSTTSS 437
Score = 58.2 bits (139), Expect = 5e-08
Identities = 52/179 (29%), Positives = 61/179 (34%), Gaps = 55/179 (30%)
Query: 625 KDIHAALQPMEGMASNQQKALPPPPASIPPP---PPLPSGLGSLSPAPPMPPVSAGPPLP 681
K+ + A +P + PP P + PPP PPL + LG P P+
Sbjct: 342 KEENKAAEPPPPKIPKIETTHPPLPPAHPPPDRKPPLAAALGEAEPPGPVDATDLPKVQI 401
Query: 682 PPPPPPPPL--PPPSSAGPPPPPPP----------------------------------- 704
PPP P P+ PPP PPPPPP
Sbjct: 402 PPPAHPAPVHQPPPLPHRPPPPPPSSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSYGAL 461
Query: 705 PPLPNSPA--PPNPGGPPPAPPPPGLAPPPPPGLFFGLGSSSSQCPRKPAIEPSCPMKP 761
PP PA P +P PP PPP P PPP F PAI P P P
Sbjct: 462 PPAYGPPAHLPYHPHVYPPNPPP---PPVPPPPASF----------PPPAIPPPTPGYP 507
Score = 50.4 bits (119), Expect = 1e-05
Identities = 29/59 (49%), Positives = 32/59 (54%), Gaps = 9/59 (15%)
Query: 646 PPPPASIPP----PPPLPSGLGSLSPA---PPMPPVSAGPPLPPPPPPPPPLPPPSSAG 697
PPPP +PP PP P GLG L PA PP P PP+PPP PP P +PP G
Sbjct: 518 PPPPPRLPPTHAVPPHPPPGLG-LPPASYPPPAVPPGGQPPVPPPIPP-PGMPPVGGLG 574
Score = 44.7 bits (104), Expect = 5e-04
Identities = 39/139 (28%), Positives = 47/139 (33%), Gaps = 28/139 (20%)
Query: 624 HKDIHAALQPMEGMASNQQKALPPPPASIPPP--PPLPSGLGSLSPAPPMP----PVSAG 677
H+ + Q + M + L PP+ P P P + S S P P P
Sbjct: 252 HQILDLYSQGKQQMPHHTPHQLQQPPSLQPTPQVPQVQQSQPSQSSEPSQPQQKDPQQPA 311
Query: 678 PPLPPPPPPPPPLPPPSS-----------------AGPPPPPPPPPLPNSPAPPNPGGPP 720
P P P P PSS A PPPP P + + P P PP
Sbjct: 312 QQQQPAQQPKKPSPQPSSPRQVKRAVVVSPKEENKAAEPPPPKIPKIETTHPPLPPAHPP 371
Query: 721 PAPPPP-----GLAPPPPP 734
P PP G A PP P
Sbjct: 372 PDRKPPLAAALGEAEPPGP 390
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.129 0.369
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 59,172,550
Number of Sequences: 37866
Number of extensions: 4312940
Number of successful extensions: 175936
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1962
Number of HSP's successfully gapped in prelim test: 1531
Number of HSP's that attempted gapping in prelim test: 32809
Number of HSP's gapped (non-prelim): 43101
length of query: 1196
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1082
effective length of database: 13,930,794
effective search space: 15073119108
effective search space used: 15073119108
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.