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Search of human proteins with 11034841
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|11034841 growth hormone releasing hormone preproprotein
[Homo sapiens]
(108 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|11034841 growth hormone releasing hormone preproprotein [Homo... 216 3e-57
gi|4507897 vasoactive intestinal peptide isoform 1 preproprotein... 44 4e-05
gi|37588853 vasoactive intestinal peptide isoform 2 preproprotei... 43 5e-05
gi|153266792 adenylate cyclase activating polypeptide precursor ... 37 0.003
gi|153266795 adenylate cyclase activating polypeptide precursor ... 37 0.003
gi|11345450 secretin preproprotein [Homo sapiens] 31 0.25
gi|192807300 calcium channel, voltage-dependent, L type, alpha 1... 27 2.7
gi|192807298 calcium channel, voltage-dependent, L type, alpha 1... 27 2.7
gi|4502527 calcium channel, voltage-dependent, L type, alpha 1D ... 27 2.7
gi|169234663 tumor protein p63 isoform 5 [Homo sapiens] 27 3.5
gi|169234661 tumor protein p63 isoform 4 [Homo sapiens] 27 3.5
gi|169234657 tumor protein p63 isoform 2 [Homo sapiens] 27 3.5
gi|31543818 tumor protein p63 isoform 1 [Homo sapiens] 27 3.5
gi|90652851 zinc finger transcription factor TRPS1 [Homo sapiens] 27 4.6
gi|21389505 janus kinase and microtubule interacting protein 1 i... 26 6.0
gi|150456473 janus kinase and microtubule interacting protein 1 ... 26 6.0
gi|154354983 regulating synaptic membrane exocytosis 2 isoform a... 26 6.0
gi|134288890 DIS3 mitotic control homolog (S. cerevisiae)-like 2... 26 6.0
gi|52487176 tripartite motif-containing 37 protein [Homo sapiens] 26 7.9
gi|15147333 tripartite motif-containing 37 protein [Homo sapiens] 26 7.9
gi|156104862 ankyrin repeat domain 38 [Homo sapiens] 26 7.9
>gi|11034841 growth hormone releasing hormone preproprotein [Homo
sapiens]
Length = 108
Score = 216 bits (550), Expect = 3e-57
Identities = 108/108 (100%), Positives = 108/108 (100%)
Query: 1 MPLWVFFFVILTLSNSSHCSPPPPLTLRMRRYADAIFTNSYRKVLGQLSARKLLQDIMSR 60
MPLWVFFFVILTLSNSSHCSPPPPLTLRMRRYADAIFTNSYRKVLGQLSARKLLQDIMSR
Sbjct: 1 MPLWVFFFVILTLSNSSHCSPPPPLTLRMRRYADAIFTNSYRKVLGQLSARKLLQDIMSR 60
Query: 61 QQGESNQERGARARLGRQVDSMWAEQKQMELESILVALLQKHSRNSQG 108
QQGESNQERGARARLGRQVDSMWAEQKQMELESILVALLQKHSRNSQG
Sbjct: 61 QQGESNQERGARARLGRQVDSMWAEQKQMELESILVALLQKHSRNSQG 108
>gi|4507897 vasoactive intestinal peptide isoform 1 preproprotein
[Homo sapiens]
Length = 170
Score = 43.5 bits (101), Expect = 4e-05
Identities = 27/86 (31%), Positives = 50/86 (58%), Gaps = 8/86 (9%)
Query: 28 RMRRYADAIFTNSYRKVLGQLSARKLLQDIMSRQQGESNQERGARARLGRQVDSMWAE-- 85
R R+AD +FT+ + K+LGQLSA+K L+ +M ++ + E + R D+++ +
Sbjct: 77 RNARHADGVFTSDFSKLLGQLSAKKYLESLMGKRVSSNISEDPVPVK--RHSDAVFTDNY 134
Query: 86 ---QKQMELESILVALLQKHSRNSQG 108
+KQM ++ L ++L R+S+G
Sbjct: 135 TRLRKQMAVKKYLNSIL-NGKRSSEG 159
Score = 32.0 bits (71), Expect = 0.11
Identities = 17/53 (32%), Positives = 34/53 (64%), Gaps = 6/53 (11%)
Query: 16 SSHCSPPPPLTLRMRRYADAIFTNSYRKVLGQLSARKLLQDIMS---RQQGES 65
SS+ S P + ++R++DA+FT++Y ++ Q++ +K L I++ +GES
Sbjct: 112 SSNISEDP---VPVKRHSDAVFTDNYTRLRKQMAVKKYLNSILNGKRSSEGES 161
>gi|37588853 vasoactive intestinal peptide isoform 2 preproprotein
[Homo sapiens]
Length = 169
Score = 43.1 bits (100), Expect = 5e-05
Identities = 27/83 (32%), Positives = 48/83 (57%), Gaps = 3/83 (3%)
Query: 28 RMRRYADAIFTNSYRKVLGQLSARKLLQDIMSRQQGESNQERGARARLGRQV--DSMWAE 85
R R+AD +FT+ + K+LGQLSA+K L+ +M ++ +++ R V D+
Sbjct: 77 RNARHADGVFTSDFSKLLGQLSAKKYLESLMGKRVSNISEDPVPVKRHSDAVFTDNYTRL 136
Query: 86 QKQMELESILVALLQKHSRNSQG 108
+KQM ++ L ++L R+S+G
Sbjct: 137 RKQMAVKKYLNSIL-NGKRSSEG 158
Score = 31.2 bits (69), Expect = 0.19
Identities = 13/40 (32%), Positives = 28/40 (70%), Gaps = 3/40 (7%)
Query: 29 MRRYADAIFTNSYRKVLGQLSARKLLQDIMS---RQQGES 65
++R++DA+FT++Y ++ Q++ +K L I++ +GES
Sbjct: 121 VKRHSDAVFTDNYTRLRKQMAVKKYLNSILNGKRSSEGES 160
>gi|153266792 adenylate cyclase activating polypeptide precursor
[Homo sapiens]
Length = 176
Score = 37.0 bits (84), Expect = 0.003
Identities = 28/80 (35%), Positives = 38/80 (47%), Gaps = 8/80 (10%)
Query: 30 RRYADAIFTNSYRKVLGQLSARKLLQDIMSR--------QQGESNQERGARARLGRQVDS 81
R A I +YRKVL QLSA K LQ +++R G+ + R G DS
Sbjct: 81 RDVAHGILNEAYRKVLDQLSAGKHLQSLVARGVGGSLGGGAGDDAEPLSKRHSDGIFTDS 140
Query: 82 MWAEQKQMELESILVALLQK 101
+KQM ++ L A+L K
Sbjct: 141 YSRYRKQMAVKKYLAAVLGK 160
Score = 31.6 bits (70), Expect = 0.14
Identities = 12/43 (27%), Positives = 27/43 (62%)
Query: 30 RRYADAIFTNSYRKVLGQLSARKLLQDIMSRQQGESNQERGAR 72
+R++D IFT+SY + Q++ +K L ++ ++ + + +G R
Sbjct: 130 KRHSDGIFTDSYSRYRKQMAVKKYLAAVLGKRYKQRVKNKGRR 172
>gi|153266795 adenylate cyclase activating polypeptide precursor
[Homo sapiens]
Length = 176
Score = 37.0 bits (84), Expect = 0.003
Identities = 28/80 (35%), Positives = 38/80 (47%), Gaps = 8/80 (10%)
Query: 30 RRYADAIFTNSYRKVLGQLSARKLLQDIMSR--------QQGESNQERGARARLGRQVDS 81
R A I +YRKVL QLSA K LQ +++R G+ + R G DS
Sbjct: 81 RDVAHGILNEAYRKVLDQLSAGKHLQSLVARGVGGSLGGGAGDDAEPLSKRHSDGIFTDS 140
Query: 82 MWAEQKQMELESILVALLQK 101
+KQM ++ L A+L K
Sbjct: 141 YSRYRKQMAVKKYLAAVLGK 160
Score = 31.6 bits (70), Expect = 0.14
Identities = 12/43 (27%), Positives = 27/43 (62%)
Query: 30 RRYADAIFTNSYRKVLGQLSARKLLQDIMSRQQGESNQERGAR 72
+R++D IFT+SY + Q++ +K L ++ ++ + + +G R
Sbjct: 130 KRHSDGIFTDSYSRYRKQMAVKKYLAAVLGKRYKQRVKNKGRR 172
>gi|11345450 secretin preproprotein [Homo sapiens]
Length = 121
Score = 30.8 bits (68), Expect = 0.25
Identities = 18/67 (26%), Positives = 33/67 (49%), Gaps = 3/67 (4%)
Query: 9 VILTLSNSSHCSPPPPLTLRMRRYADAIFTNSYRKVLGQLSARKLLQDIMSRQQGESNQE 68
++L L S P PP R RR++D FT+ ++ ++LLQ ++ ++ + +
Sbjct: 8 LLLLLLGGSAARPAPP---RARRHSDGTFTSELSRLREGARLQRLLQGLVGKRSEQDAEN 64
Query: 69 RGARARL 75
A RL
Sbjct: 65 SMAWTRL 71
>gi|192807300 calcium channel, voltage-dependent, L type, alpha 1D
subunit isoform b [Homo sapiens]
Length = 2161
Score = 27.3 bits (59), Expect = 2.7
Identities = 14/29 (48%), Positives = 18/29 (62%)
Query: 45 LGQLSARKLLQDIMSRQQGESNQERGARA 73
+G LS RK Q S++QG S+ R ARA
Sbjct: 77 VGSLSQRKRQQYAKSKKQGNSSNSRPARA 105
>gi|192807298 calcium channel, voltage-dependent, L type, alpha 1D
subunit isoform c [Homo sapiens]
Length = 2137
Score = 27.3 bits (59), Expect = 2.7
Identities = 14/29 (48%), Positives = 18/29 (62%)
Query: 45 LGQLSARKLLQDIMSRQQGESNQERGARA 73
+G LS RK Q S++QG S+ R ARA
Sbjct: 77 VGSLSQRKRQQYAKSKKQGNSSNSRPARA 105
>gi|4502527 calcium channel, voltage-dependent, L type, alpha 1D
subunit isoform a [Homo sapiens]
Length = 2181
Score = 27.3 bits (59), Expect = 2.7
Identities = 14/29 (48%), Positives = 18/29 (62%)
Query: 45 LGQLSARKLLQDIMSRQQGESNQERGARA 73
+G LS RK Q S++QG S+ R ARA
Sbjct: 77 VGSLSQRKRQQYAKSKKQGNSSNSRPARA 105
>gi|169234663 tumor protein p63 isoform 5 [Homo sapiens]
Length = 461
Score = 26.9 bits (58), Expect = 3.5
Identities = 8/14 (57%), Positives = 13/14 (92%)
Query: 11 LTLSNSSHCSPPPP 24
L++ ++SHC+PPPP
Sbjct: 435 LSMPSTSHCTPPPP 448
>gi|169234661 tumor protein p63 isoform 4 [Homo sapiens]
Length = 586
Score = 26.9 bits (58), Expect = 3.5
Identities = 8/14 (57%), Positives = 13/14 (92%)
Query: 11 LTLSNSSHCSPPPP 24
L++ ++SHC+PPPP
Sbjct: 435 LSMPSTSHCTPPPP 448
>gi|169234657 tumor protein p63 isoform 2 [Homo sapiens]
Length = 555
Score = 26.9 bits (58), Expect = 3.5
Identities = 8/14 (57%), Positives = 13/14 (92%)
Query: 11 LTLSNSSHCSPPPP 24
L++ ++SHC+PPPP
Sbjct: 529 LSMPSTSHCTPPPP 542
>gi|31543818 tumor protein p63 isoform 1 [Homo sapiens]
Length = 680
Score = 26.9 bits (58), Expect = 3.5
Identities = 8/14 (57%), Positives = 13/14 (92%)
Query: 11 LTLSNSSHCSPPPP 24
L++ ++SHC+PPPP
Sbjct: 529 LSMPSTSHCTPPPP 542
>gi|90652851 zinc finger transcription factor TRPS1 [Homo sapiens]
Length = 1294
Score = 26.6 bits (57), Expect = 4.6
Identities = 19/72 (26%), Positives = 34/72 (47%), Gaps = 3/72 (4%)
Query: 20 SPPPPLTLRMRRYADAIFTNSYRKVLGQLSARKLLQDIMSRQQGESNQERGARARLGRQV 79
S P PL + + + I RK +L+ L + +++QQ SN+E+ + L R+
Sbjct: 941 STPRPLNIIKQNNGEQIIRRRTRK---RLNPEALQAEQLNKQQRGSNEEQVNGSPLERRS 997
Query: 80 DSMWAEQKQMEL 91
+ E Q E+
Sbjct: 998 EDHLTESHQREI 1009
>gi|21389505 janus kinase and microtubule interacting protein 1
isoform 2 [Homo sapiens]
Length = 626
Score = 26.2 bits (56), Expect = 6.0
Identities = 22/67 (32%), Positives = 30/67 (44%), Gaps = 3/67 (4%)
Query: 30 RRYADAIFTNSYRKVLGQLSARKLLQDIMSRQQGESNQERGARARLGRQVDSMWAEQKQM 89
R AD F R+ A LLQ+ + G + ER AR R Q D + + K
Sbjct: 481 REEADLRFCQLTREYQALQRAYALLQEQVG---GTLDAEREARTREQLQADLLRCQAKIE 537
Query: 90 ELESILV 96
+LE +LV
Sbjct: 538 DLEKLLV 544
>gi|150456473 janus kinase and microtubule interacting protein 1
isoform 1 [Homo sapiens]
Length = 831
Score = 26.2 bits (56), Expect = 6.0
Identities = 22/67 (32%), Positives = 30/67 (44%), Gaps = 3/67 (4%)
Query: 30 RRYADAIFTNSYRKVLGQLSARKLLQDIMSRQQGESNQERGARARLGRQVDSMWAEQKQM 89
R AD F R+ A LLQ+ + G + ER AR R Q D + + K
Sbjct: 481 REEADLRFCQLTREYQALQRAYALLQEQVG---GTLDAEREARTREQLQADLLRCQAKIE 537
Query: 90 ELESILV 96
+LE +LV
Sbjct: 538 DLEKLLV 544
>gi|154354983 regulating synaptic membrane exocytosis 2 isoform a
[Homo sapiens]
Length = 1349
Score = 26.2 bits (56), Expect = 6.0
Identities = 13/43 (30%), Positives = 24/43 (55%)
Query: 51 RKLLQDIMSRQQGESNQERGARARLGRQVDSMWAEQKQMELES 93
RK++ +M RQ+ E +E+ +L +Q + + K+M ES
Sbjct: 37 RKIILAVMDRQKKEEEKEQSVLKKLHQQFEMYKEQVKKMGEES 79
>gi|134288890 DIS3 mitotic control homolog (S. cerevisiae)-like 2
[Homo sapiens]
Length = 885
Score = 26.2 bits (56), Expect = 6.0
Identities = 18/81 (22%), Positives = 35/81 (43%), Gaps = 5/81 (6%)
Query: 26 TLRMRRYADAIFTNSYRKVLGQLSARKLLQDIMSRQQGESNQERGARARLGRQVDSMW-- 83
T +RR+AD + LG + D + +Q N R A R+ S++
Sbjct: 700 TSPIRRFADVLVHRLLAAALGYRERLDMAPDTLQKQADHCNDRRMASKRVQELSTSLFFA 759
Query: 84 ---AEQKQMELESILVALLQK 101
E +E E++++ +L++
Sbjct: 760 VLVKESGPLESEAMVMGILKQ 780
>gi|52487176 tripartite motif-containing 37 protein [Homo sapiens]
Length = 964
Score = 25.8 bits (55), Expect = 7.9
Identities = 11/37 (29%), Positives = 20/37 (54%)
Query: 71 ARARLGRQVDSMWAEQKQMELESILVALLQKHSRNSQ 107
A +L V+ WAE+ +L+++ + L KH N +
Sbjct: 56 APLQLRELVNCRWAEEVTQQLDTLQLCSLTKHEENEK 92
>gi|15147333 tripartite motif-containing 37 protein [Homo sapiens]
Length = 964
Score = 25.8 bits (55), Expect = 7.9
Identities = 11/37 (29%), Positives = 20/37 (54%)
Query: 71 ARARLGRQVDSMWAEQKQMELESILVALLQKHSRNSQ 107
A +L V+ WAE+ +L+++ + L KH N +
Sbjct: 56 APLQLRELVNCRWAEEVTQQLDTLQLCSLTKHEENEK 92
>gi|156104862 ankyrin repeat domain 38 [Homo sapiens]
Length = 995
Score = 25.8 bits (55), Expect = 7.9
Identities = 26/103 (25%), Positives = 48/103 (46%), Gaps = 9/103 (8%)
Query: 15 NSSHCSPPPPLTLRMRRYADAIFTNSY---RKVLGQLSA-RKLLQDIMSRQQGESNQERG 70
N S PPPP+ + MR + S R G +S+ ++ + + G + +
Sbjct: 306 NISEIPPPPPVEVDMRSIGIRVTEESLGLARVDPGSISSLKQQVSALEGELSGRTEELAQ 365
Query: 71 ARARLGRQVDSMWA-EQKQMELESILVAL----LQKHSRNSQG 108
R L +Q + + A EQ+ ELE + L Q++++++QG
Sbjct: 366 VRTALQQQEEEIKAREQRIRELEFTVAQLEGQFHQENAKDTQG 408
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.132 0.384
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 3,969,842
Number of Sequences: 37866
Number of extensions: 131441
Number of successful extensions: 577
Number of sequences better than 10.0: 21
Number of HSP's better than 10.0 without gapping: 16
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 555
Number of HSP's gapped (non-prelim): 27
length of query: 108
length of database: 18,247,518
effective HSP length: 78
effective length of query: 30
effective length of database: 15,293,970
effective search space: 458819100
effective search space used: 458819100
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 55 (25.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.