Guide to the Human Genome
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Search of human proteins with 156416007

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|156416007 COMM domain containing 9 isoform 2 [Homo sapiens]
         (156 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|156416007 COMM domain containing 9 isoform 2 [Homo sapiens]        300   3e-82
gi|156416005 COMM domain containing 9 isoform 1 [Homo sapiens]        280   5e-76
gi|8923458 COMM domain containing 8 [Homo sapiens]                     38   0.003
gi|6912278 COMM domain containing 3 [Homo sapiens]                     38   0.004
gi|124487382 COMM domain containing 5 [Homo sapiens]                   37   0.007
gi|154800418 COMM domain containing 5 [Homo sapiens]                   37   0.007
gi|19923430 COMM domain containing 5 [Homo sapiens]                    37   0.007
gi|45545435 COMM domain containing 2 [Homo sapiens]                    37   0.007
gi|169166962 PREDICTED: similar to COMM domain containing 5 [Hom...    34   0.044
gi|169166771 PREDICTED: similar to COMM domain containing 5 [Hom...    34   0.044
gi|169166418 PREDICTED: similar to COMM domain containing 5 [Hom...    34   0.044
gi|221307473 ArfGAP with SH3 domain, ankyrin repeat and PH domai...    33   0.098
gi|19923540 ArfGAP with SH3 domain, ankyrin repeat and PH domain...    33   0.098
gi|194306650 SET domain and mariner transposase fusion [Homo sap...    30   0.83 
gi|7706663 COMM domain containing 10 [Homo sapiens]                    30   1.1  
gi|27436978 potassium voltage-gated channel, Isk-related family,...    29   1.8  
gi|63047871 hypothetical protein LOC122525 [Homo sapiens]              29   1.8  
gi|22749079 MURR1 [Homo sapiens]                                       28   3.2  
gi|223671858 hypothetical protein LOC389761 [Homo sapiens]             27   5.4  
gi|112293287 tudor domain containing 7 [Homo sapiens]                  27   5.4  
gi|223972636 tRNA-intron nuclease 2 isoform 3 [Homo sapiens]           27   7.0  
gi|223972632 tRNA-intron nuclease 2 isoform 1 [Homo sapiens]           27   7.0  
gi|13376882 tRNA-intron nuclease 2 isoform 1 [Homo sapiens]            27   7.0  
gi|229892328 IQ motif containing C isoform 1 [Homo sapiens]            27   7.0  
gi|229892326 IQ motif containing C isoform 2 [Homo sapiens]            27   7.0  
gi|223972634 tRNA-intron nuclease 2 isoform 2 [Homo sapiens]           27   7.0  
gi|150170725 zinc and ring finger 4 [Homo sapiens]                     27   7.0  

>gi|156416007 COMM domain containing 9 isoform 2 [Homo sapiens]
          Length = 156

 Score =  300 bits (768), Expect = 3e-82
 Identities = 156/156 (100%), Positives = 156/156 (100%)

Query: 1   MAALTAEHFAALQSLLKLLQALHRLTRLVAFRDLSSAEAILALFPENFHQNLKNLLTKII 60
           MAALTAEHFAALQSLLKLLQALHRLTRLVAFRDLSSAEAILALFPENFHQNLKNLLTKII
Sbjct: 1   MAALTAEHFAALQSLLKLLQALHRLTRLVAFRDLSSAEAILALFPENFHQNLKNLLTKII 60

Query: 61  LEHVSTWRTEAQANQISLPRLVDLDWRVDIKTSSDSISRMAVPTCLLQMKIQEDPSLCGD 120
           LEHVSTWRTEAQANQISLPRLVDLDWRVDIKTSSDSISRMAVPTCLLQMKIQEDPSLCGD
Sbjct: 61  LEHVSTWRTEAQANQISLPRLVDLDWRVDIKTSSDSISRMAVPTCLLQMKIQEDPSLCGD 120

Query: 121 KPSISAVTVELSKETLDTMLDGLGRIRDQLSAVASK 156
           KPSISAVTVELSKETLDTMLDGLGRIRDQLSAVASK
Sbjct: 121 KPSISAVTVELSKETLDTMLDGLGRIRDQLSAVASK 156


>gi|156416005 COMM domain containing 9 isoform 1 [Homo sapiens]
          Length = 198

 Score =  280 bits (715), Expect = 5e-76
 Identities = 156/198 (78%), Positives = 156/198 (78%), Gaps = 42/198 (21%)

Query: 1   MAALTAEHFAALQSLLK------------------------------------------L 18
           MAALTAEHFAALQSLLK                                          L
Sbjct: 1   MAALTAEHFAALQSLLKASSKDVVRQLCQESFSSSALGLKKLLDVTCSSLSVTQEEAEEL 60

Query: 19  LQALHRLTRLVAFRDLSSAEAILALFPENFHQNLKNLLTKIILEHVSTWRTEAQANQISL 78
           LQALHRLTRLVAFRDLSSAEAILALFPENFHQNLKNLLTKIILEHVSTWRTEAQANQISL
Sbjct: 61  LQALHRLTRLVAFRDLSSAEAILALFPENFHQNLKNLLTKIILEHVSTWRTEAQANQISL 120

Query: 79  PRLVDLDWRVDIKTSSDSISRMAVPTCLLQMKIQEDPSLCGDKPSISAVTVELSKETLDT 138
           PRLVDLDWRVDIKTSSDSISRMAVPTCLLQMKIQEDPSLCGDKPSISAVTVELSKETLDT
Sbjct: 121 PRLVDLDWRVDIKTSSDSISRMAVPTCLLQMKIQEDPSLCGDKPSISAVTVELSKETLDT 180

Query: 139 MLDGLGRIRDQLSAVASK 156
           MLDGLGRIRDQLSAVASK
Sbjct: 181 MLDGLGRIRDQLSAVASK 198


>gi|8923458 COMM domain containing 8 [Homo sapiens]
          Length = 183

 Score = 38.1 bits (87), Expect = 0.003
 Identities = 19/68 (27%), Positives = 36/68 (52%), Gaps = 7/68 (10%)

Query: 76  ISLPRLVDLDWRVDIKTSSDSISRMAVPTCLLQMKIQEDPSLCGDKPSISAVTVELSKET 135
           IS  +L D DW+V +  SSD I+ + +P   L + ++E+         +   ++E+S+E 
Sbjct: 112 ISSAQLQDFDWQVKLALSSDKIAALRMPLLSLHLDVKEN-------GEVKPYSIEMSREE 164

Query: 136 LDTMLDGL 143
           L  ++  L
Sbjct: 165 LQNLIQSL 172


>gi|6912278 COMM domain containing 3 [Homo sapiens]
          Length = 195

 Score = 37.7 bits (86), Expect = 0.004
 Identities = 20/72 (27%), Positives = 37/72 (51%), Gaps = 8/72 (11%)

Query: 77  SLPRLVDLDWRVDIKTSSDSISRMAVPTCLLQMKIQEDPSLCGDKPSISAVTVELSKETL 136
           SLP + D+ WR++ +  ++ + RM  P  L+ + +Q       D PS   ++   S E L
Sbjct: 121 SLPHITDVSWRLEYQIKTNQLHRMYRPAYLVTLSVQNT-----DSPSYPEISFSCSMEQL 175

Query: 137 DTMLDGLGRIRD 148
               D +G+++D
Sbjct: 176 Q---DLVGKLKD 184


>gi|124487382 COMM domain containing 5 [Homo sapiens]
          Length = 224

 Score = 37.0 bits (84), Expect = 0.007
 Identities = 15/43 (34%), Positives = 26/43 (60%)

Query: 71  AQANQISLPRLVDLDWRVDIKTSSDSISRMAVPTCLLQMKIQE 113
           AQ     LP + D  WRVD+  S+ +++R   P+ L+Q+K+ +
Sbjct: 142 AQQQGAWLPHVADFRWRVDVAISTSALARSLQPSVLMQLKLSD 184


>gi|154800418 COMM domain containing 5 [Homo sapiens]
          Length = 224

 Score = 37.0 bits (84), Expect = 0.007
 Identities = 15/43 (34%), Positives = 26/43 (60%)

Query: 71  AQANQISLPRLVDLDWRVDIKTSSDSISRMAVPTCLLQMKIQE 113
           AQ     LP + D  WRVD+  S+ +++R   P+ L+Q+K+ +
Sbjct: 142 AQQQGAWLPHVADFRWRVDVAISTSALARSLQPSVLMQLKLSD 184


>gi|19923430 COMM domain containing 5 [Homo sapiens]
          Length = 224

 Score = 37.0 bits (84), Expect = 0.007
 Identities = 15/43 (34%), Positives = 26/43 (60%)

Query: 71  AQANQISLPRLVDLDWRVDIKTSSDSISRMAVPTCLLQMKIQE 113
           AQ     LP + D  WRVD+  S+ +++R   P+ L+Q+K+ +
Sbjct: 142 AQQQGAWLPHVADFRWRVDVAISTSALARSLQPSVLMQLKLSD 184


>gi|45545435 COMM domain containing 2 [Homo sapiens]
          Length = 199

 Score = 37.0 bits (84), Expect = 0.007
 Identities = 18/73 (24%), Positives = 39/73 (53%)

Query: 42  ALFPENFHQNLKNLLTKIILEHVSTWRTEAQANQISLPRLVDLDWRVDIKTSSDSISRMA 101
           ++F   F + L  LL ++ L++    RT       SLP   +L+WR+D++ +S S+ +  
Sbjct: 85  SVFVLGFSEELNKLLLQLYLDNRKEIRTILSELAPSLPSYHNLEWRLDVQLASRSLRQQI 144

Query: 102 VPTCLLQMKIQED 114
            P   +++ + ++
Sbjct: 145 KPAVTIKLHLNQN 157


>gi|169166962 PREDICTED: similar to COMM domain containing 5 [Homo
           sapiens]
          Length = 273

 Score = 34.3 bits (77), Expect = 0.044
 Identities = 14/43 (32%), Positives = 24/43 (55%)

Query: 71  AQANQISLPRLVDLDWRVDIKTSSDSISRMAVPTCLLQMKIQE 113
           AQ     LP + D  W VD+  S+ +++R   P  L+Q+K+ +
Sbjct: 191 AQQQGAWLPHVADFQWWVDVTISTSALARFLQPRVLMQLKLSD 233


>gi|169166771 PREDICTED: similar to COMM domain containing 5 [Homo
           sapiens]
          Length = 273

 Score = 34.3 bits (77), Expect = 0.044
 Identities = 14/43 (32%), Positives = 24/43 (55%)

Query: 71  AQANQISLPRLVDLDWRVDIKTSSDSISRMAVPTCLLQMKIQE 113
           AQ     LP + D  W VD+  S+ +++R   P  L+Q+K+ +
Sbjct: 191 AQQQGAWLPHVADFQWWVDVTISTSALARFLQPRVLMQLKLSD 233


>gi|169166418 PREDICTED: similar to COMM domain containing 5 [Homo
           sapiens]
          Length = 273

 Score = 34.3 bits (77), Expect = 0.044
 Identities = 14/43 (32%), Positives = 24/43 (55%)

Query: 71  AQANQISLPRLVDLDWRVDIKTSSDSISRMAVPTCLLQMKIQE 113
           AQ     LP + D  W VD+  S+ +++R   P  L+Q+K+ +
Sbjct: 191 AQQQGAWLPHVADFQWWVDVTISTSALARFLQPRVLMQLKLSD 233


>gi|221307473 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
           isoform b [Homo sapiens]
          Length = 894

 Score = 33.1 bits (74), Expect = 0.098
 Identities = 29/108 (26%), Positives = 45/108 (41%), Gaps = 13/108 (12%)

Query: 5   TAEHFAALQSLLKLLQALHRLTRLVAFRDLSSAEAILALFPENFHQNLKNLLTKIILEHV 64
           TA H+AAL +    L+ L +   LV   +  + E  L +  +  H+  + LL        
Sbjct: 615 TALHYAALYNQPDCLKLLLKGRALVGTVN-EAGETALDIARKKHHKECEELLE------- 666

Query: 65  STWRTEAQANQISLPRLVDLDWRVDIKTSSDSISRMAVPTCLLQMKIQ 112
                +AQA   + P  VD  W +  +  SDS        CLL++  Q
Sbjct: 667 -----QAQAGTFAFPLHVDYSWVISTEPGSDSEEDEEEKRCLLKLPAQ 709


>gi|19923540 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
           isoform a [Homo sapiens]
          Length = 903

 Score = 33.1 bits (74), Expect = 0.098
 Identities = 29/108 (26%), Positives = 45/108 (41%), Gaps = 13/108 (12%)

Query: 5   TAEHFAALQSLLKLLQALHRLTRLVAFRDLSSAEAILALFPENFHQNLKNLLTKIILEHV 64
           TA H+AAL +    L+ L +   LV   +  + E  L +  +  H+  + LL        
Sbjct: 624 TALHYAALYNQPDCLKLLLKGRALVGTVN-EAGETALDIARKKHHKECEELLE------- 675

Query: 65  STWRTEAQANQISLPRLVDLDWRVDIKTSSDSISRMAVPTCLLQMKIQ 112
                +AQA   + P  VD  W +  +  SDS        CLL++  Q
Sbjct: 676 -----QAQAGTFAFPLHVDYSWVISTEPGSDSEEDEEEKRCLLKLPAQ 718


>gi|194306650 SET domain and mariner transposase fusion [Homo
           sapiens]
          Length = 684

 Score = 30.0 bits (66), Expect = 0.83
 Identities = 12/30 (40%), Positives = 19/30 (63%)

Query: 112 QEDPSLCGDKPSISAVTVELSKETLDTMLD 141
           +++PS+CG  PS+      L+ ET+  MLD
Sbjct: 318 EKEPSMCGSAPSVFPSCKRLTLETMKMMLD 347


>gi|7706663 COMM domain containing 10 [Homo sapiens]
          Length = 202

 Score = 29.6 bits (65), Expect = 1.1
 Identities = 22/97 (22%), Positives = 47/97 (48%), Gaps = 12/97 (12%)

Query: 64  VSTWRTEAQAN------QISLP-RLVDLDWRVDIKTSSDSISRMAVPTCLLQMKIQEDPS 116
           V+TW +  Q        +I  P +L  + W+++++ +  + +++  P  +LQ+ +  +  
Sbjct: 110 VNTWSSMGQETVEKFRQRILAPCKLETVGWQLNLQMAHSAQAKLKSPQAVLQLGVNNE-- 167

Query: 117 LCGDKPSISAVTVELSKETLDTMLDGLGRIRDQLSAV 153
              D  S+  V VE S + L    + L  I+ QL ++
Sbjct: 168 ---DSKSLEKVLVEFSHKELFDFYNKLETIQAQLDSL 201


>gi|27436978 potassium voltage-gated channel, Isk-related family,
          member 2 [Homo sapiens]
          Length = 123

 Score = 28.9 bits (63), Expect = 1.8
 Identities = 12/39 (30%), Positives = 21/39 (53%)

Query: 47 NFHQNLKNLLTKIILEHVSTWRTEAQANQISLPRLVDLD 85
          NF Q L+++  +I + ++  WR    A Q +L   VD +
Sbjct: 6  NFTQTLEDVFRRIFITYMDNWRQNTTAEQEALQAKVDAE 44


>gi|63047871 hypothetical protein LOC122525 [Homo sapiens]
          Length = 310

 Score = 28.9 bits (63), Expect = 1.8
 Identities = 20/65 (30%), Positives = 34/65 (52%), Gaps = 5/65 (7%)

Query: 16  LKLLQALHRLTRLVAFRDLSSAEAILALFP---ENFHQNLKNLLTKIILEHVSTWR--TE 70
           +KLL    ++ +     ++  A  I+ LF    +NF +NL+NL++ I   + S WR  T 
Sbjct: 104 VKLLWIWDKMEKQQYKSEVHKASLIIDLFGNEHDNFTKNLENLMSTIQESYCSNWRCPTR 163

Query: 71  AQANQ 75
            Q +Q
Sbjct: 164 VQEDQ 168


>gi|22749079 MURR1 [Homo sapiens]
          Length = 190

 Score = 28.1 bits (61), Expect = 3.2
 Identities = 17/77 (22%), Positives = 37/77 (48%), Gaps = 14/77 (18%)

Query: 84  LDWRVDIKTSSDSISRMAVPTCLLQMKI----QEDPSLCGDKPSISAVTVELSKETLDTM 139
           L WRVD K+ S   +++  P  ++++++    QE   LC          +E  +  ++ +
Sbjct: 122 LSWRVDGKSQSRHSAQIHTPVAIIELELGKYGQESEFLC----------LEFDEVKVNQI 171

Query: 140 LDGLGRIRDQLSAVASK 156
           L  L  + + +S + S+
Sbjct: 172 LKTLSEVEESISTLISQ 188


>gi|223671858 hypothetical protein LOC389761 [Homo sapiens]
          Length = 917

 Score = 27.3 bits (59), Expect = 5.4
 Identities = 27/95 (28%), Positives = 47/95 (49%), Gaps = 13/95 (13%)

Query: 44  FPENFHQNLKNLLTKIILEHVSTWRTEAQANQISLPRLVDLDWRVDIKTSSD----SISR 99
           FP +FH+   N+L+   +E+V  ++     +Q + P+   L    D +TSSD    S S 
Sbjct: 749 FPRSFHERSSNMLS---MENVGNYQ---GCSQETAPKNHLLH---DPETSSDEDLRSNSE 799

Query: 100 MAVPTCLLQMKIQEDPSLCGDKPSISAVTVELSKE 134
             + T ++ +   +     G K   +A+TV LSK+
Sbjct: 800 RDLGTHMMHLSGNDSGVRLGQKQLENALTVHLSKK 834


>gi|112293287 tudor domain containing 7 [Homo sapiens]
          Length = 1098

 Score = 27.3 bits (59), Expect = 5.4
 Identities = 10/25 (40%), Positives = 18/25 (72%)

Query: 46  ENFHQNLKNLLTKIILEHVSTWRTE 70
           ENF +NL +++ K +++H S + TE
Sbjct: 875 ENFRKNLTDVIKKSMVDHTSAFSTE 899


>gi|223972636 tRNA-intron nuclease 2 isoform 3 [Homo sapiens]
          Length = 406

 Score = 26.9 bits (58), Expect = 7.0
 Identities = 19/79 (24%), Positives = 39/79 (49%), Gaps = 9/79 (11%)

Query: 35  SSAEAILALFPENFHQNLKNLLTKIILEHVSTWRTEAQANQISLPRLVDLDWRVDIKTSS 94
           +S   I+ L  ++F  +L+  L+         W++ A  +++S+    +L     IK S+
Sbjct: 319 ASYSVIIELVDDHFEGSLRRPLS---------WKSLAALSRVSVNVSKELMLCYLIKPST 369

Query: 95  DSISRMAVPTCLLQMKIQE 113
            +   M  P C+ ++K+QE
Sbjct: 370 MTDKEMESPECMKRIKVQE 388


>gi|223972632 tRNA-intron nuclease 2 isoform 1 [Homo sapiens]
          Length = 465

 Score = 26.9 bits (58), Expect = 7.0
 Identities = 19/79 (24%), Positives = 39/79 (49%), Gaps = 9/79 (11%)

Query: 35  SSAEAILALFPENFHQNLKNLLTKIILEHVSTWRTEAQANQISLPRLVDLDWRVDIKTSS 94
           +S   I+ L  ++F  +L+  L+         W++ A  +++S+    +L     IK S+
Sbjct: 378 ASYSVIIELVDDHFEGSLRRPLS---------WKSLAALSRVSVNVSKELMLCYLIKPST 428

Query: 95  DSISRMAVPTCLLQMKIQE 113
            +   M  P C+ ++K+QE
Sbjct: 429 MTDKEMESPECMKRIKVQE 447


>gi|13376882 tRNA-intron nuclease 2 isoform 1 [Homo sapiens]
          Length = 465

 Score = 26.9 bits (58), Expect = 7.0
 Identities = 19/79 (24%), Positives = 39/79 (49%), Gaps = 9/79 (11%)

Query: 35  SSAEAILALFPENFHQNLKNLLTKIILEHVSTWRTEAQANQISLPRLVDLDWRVDIKTSS 94
           +S   I+ L  ++F  +L+  L+         W++ A  +++S+    +L     IK S+
Sbjct: 378 ASYSVIIELVDDHFEGSLRRPLS---------WKSLAALSRVSVNVSKELMLCYLIKPST 428

Query: 95  DSISRMAVPTCLLQMKIQE 113
            +   M  P C+ ++K+QE
Sbjct: 429 MTDKEMESPECMKRIKVQE 447


>gi|229892328 IQ motif containing C isoform 1 [Homo sapiens]
          Length = 546

 Score = 26.9 bits (58), Expect = 7.0
 Identities = 13/19 (68%), Positives = 14/19 (73%)

Query: 104 TCLLQMKIQEDPSLCGDKP 122
           TCLLQMKI ED +  G KP
Sbjct: 392 TCLLQMKILEDQTPRGLKP 410


>gi|229892326 IQ motif containing C isoform 2 [Homo sapiens]
          Length = 466

 Score = 26.9 bits (58), Expect = 7.0
 Identities = 13/19 (68%), Positives = 14/19 (73%)

Query: 104 TCLLQMKIQEDPSLCGDKP 122
           TCLLQMKI ED +  G KP
Sbjct: 312 TCLLQMKILEDQTPRGLKP 330


>gi|223972634 tRNA-intron nuclease 2 isoform 2 [Homo sapiens]
          Length = 439

 Score = 26.9 bits (58), Expect = 7.0
 Identities = 19/79 (24%), Positives = 39/79 (49%), Gaps = 9/79 (11%)

Query: 35  SSAEAILALFPENFHQNLKNLLTKIILEHVSTWRTEAQANQISLPRLVDLDWRVDIKTSS 94
           +S   I+ L  ++F  +L+  L+         W++ A  +++S+    +L     IK S+
Sbjct: 352 ASYSVIIELVDDHFEGSLRRPLS---------WKSLAALSRVSVNVSKELMLCYLIKPST 402

Query: 95  DSISRMAVPTCLLQMKIQE 113
            +   M  P C+ ++K+QE
Sbjct: 403 MTDKEMESPECMKRIKVQE 421


>gi|150170725 zinc and ring finger 4 [Homo sapiens]
          Length = 429

 Score = 26.9 bits (58), Expect = 7.0
 Identities = 12/27 (44%), Positives = 17/27 (62%)

Query: 113 EDPSLCGDKPSISAVTVELSKETLDTM 139
           EDPSL G +P I A+ V+L    L+ +
Sbjct: 372 EDPSLPGHRPPIWAIQVQLRSRRLELL 398


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.131    0.363 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 4,554,359
Number of Sequences: 37866
Number of extensions: 155934
Number of successful extensions: 418
Number of sequences better than 10.0: 27
Number of HSP's better than 10.0 without gapping: 19
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 395
Number of HSP's gapped (non-prelim): 31
length of query: 156
length of database: 18,247,518
effective HSP length: 94
effective length of query: 62
effective length of database: 14,688,114
effective search space: 910663068
effective search space used: 910663068
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 57 (26.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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