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Search of human proteins with 156104908
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|156104908 myosin heavy chain 6 [Homo sapiens]
(1939 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|156104908 myosin heavy chain 6 [Homo sapiens] 3753 0.0
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s... 3494 0.0
gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo... 3122 0.0
gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo... 3108 0.0
gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo... 3108 0.0
gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo ... 3107 0.0
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [... 3104 0.0
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H... 3054 0.0
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo... 2992 0.0
gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta ... 2655 0.0
gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens] 2409 0.0
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 1432 0.0
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 1432 0.0
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 1430 0.0
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 1430 0.0
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 1406 0.0
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 1403 0.0
gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens] 1295 0.0
gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens] 1295 0.0
gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens] 1285 0.0
gi|215982791 myosin VA isoform 1 [Homo sapiens] 617 e-176
gi|215982794 myosin VA isoform 2 [Homo sapiens] 616 e-176
gi|153945715 myosin VC [Homo sapiens] 608 e-173
gi|122937345 myosin VB [Homo sapiens] 583 e-166
gi|28416946 myosin 18A isoform a [Homo sapiens] 515 e-145
gi|42794779 myosin 18A isoform b [Homo sapiens] 513 e-145
gi|154354979 myosin X [Homo sapiens] 483 e-136
gi|189083802 myosin VIIA isoform 2 [Homo sapiens] 471 e-132
gi|189083800 myosin VIIA isoform 3 [Homo sapiens] 471 e-132
gi|189083798 myosin VIIA isoform 1 [Homo sapiens] 471 e-132
>gi|156104908 myosin heavy chain 6 [Homo sapiens]
Length = 1939
Score = 3753 bits (9732), Expect = 0.0
Identities = 1939/1939 (100%), Positives = 1939/1939 (100%)
Query: 1 MTDAQMADFGAAAQYLRKSEKERLEAQTRPFDIRTECFVPDDKEEFVKAKILSREGGKVI 60
MTDAQMADFGAAAQYLRKSEKERLEAQTRPFDIRTECFVPDDKEEFVKAKILSREGGKVI
Sbjct: 1 MTDAQMADFGAAAQYLRKSEKERLEAQTRPFDIRTECFVPDDKEEFVKAKILSREGGKVI 60
Query: 61 AETENGKTVTVKEDQVLQQNPPKFDKIEDMAMLTFLHEPAVLFNLKERYAAWMIYTYSGL 120
AETENGKTVTVKEDQVLQQNPPKFDKIEDMAMLTFLHEPAVLFNLKERYAAWMIYTYSGL
Sbjct: 61 AETENGKTVTVKEDQVLQQNPPKFDKIEDMAMLTFLHEPAVLFNLKERYAAWMIYTYSGL 120
Query: 121 FCVTVNPYKWLPVYNAEVVAAYRGKKRSEAPPHIFSISDNAYQYMLTDRENQSILITGES 180
FCVTVNPYKWLPVYNAEVVAAYRGKKRSEAPPHIFSISDNAYQYMLTDRENQSILITGES
Sbjct: 121 FCVTVNPYKWLPVYNAEVVAAYRGKKRSEAPPHIFSISDNAYQYMLTDRENQSILITGES 180
Query: 181 GAGKTVNTKRVIQYFASIAAIGDRGKKDNANANKGTLEDQIIQANPALEAFGNAKTVRND 240
GAGKTVNTKRVIQYFASIAAIGDRGKKDNANANKGTLEDQIIQANPALEAFGNAKTVRND
Sbjct: 181 GAGKTVNTKRVIQYFASIAAIGDRGKKDNANANKGTLEDQIIQANPALEAFGNAKTVRND 240
Query: 241 NSSRFGKFIRIHFGATGKLASADIETYLLEKSRVIFQLKAERNYHIFYQILSNKKPELLD 300
NSSRFGKFIRIHFGATGKLASADIETYLLEKSRVIFQLKAERNYHIFYQILSNKKPELLD
Sbjct: 241 NSSRFGKFIRIHFGATGKLASADIETYLLEKSRVIFQLKAERNYHIFYQILSNKKPELLD 300
Query: 301 MLLVTNNPYDYAFVSQGEVSVASIDDSEELMATDSAFDVLGFTSEEKAGVYKLTGAIMHY 360
MLLVTNNPYDYAFVSQGEVSVASIDDSEELMATDSAFDVLGFTSEEKAGVYKLTGAIMHY
Sbjct: 301 MLLVTNNPYDYAFVSQGEVSVASIDDSEELMATDSAFDVLGFTSEEKAGVYKLTGAIMHY 360
Query: 361 GNMKFKQKQREEQAEPDGTEDADKSAYLMGLNSADLLKGLCHPRVKVGNEYVTKGQSVQQ 420
GNMKFKQKQREEQAEPDGTEDADKSAYLMGLNSADLLKGLCHPRVKVGNEYVTKGQSVQQ
Sbjct: 361 GNMKFKQKQREEQAEPDGTEDADKSAYLMGLNSADLLKGLCHPRVKVGNEYVTKGQSVQQ 420
Query: 421 VYYSIGALAKAVYEKMFNWMVTRINATLETKQPRQYFIGVLDIAGFEIFDFNSFEQLCIN 480
VYYSIGALAKAVYEKMFNWMVTRINATLETKQPRQYFIGVLDIAGFEIFDFNSFEQLCIN
Sbjct: 421 VYYSIGALAKAVYEKMFNWMVTRINATLETKQPRQYFIGVLDIAGFEIFDFNSFEQLCIN 480
Query: 481 FTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLQACIDLIEKPMGIMSILEEECM 540
FTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLQACIDLIEKPMGIMSILEEECM
Sbjct: 481 FTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLQACIDLIEKPMGIMSILEEECM 540
Query: 541 FPKATDMTFKAKLYDNHLGKSNNFQKPRNIKGKQEAHFSLIHYAGTVDYNILGWLEKNKD 600
FPKATDMTFKAKLYDNHLGKSNNFQKPRNIKGKQEAHFSLIHYAGTVDYNILGWLEKNKD
Sbjct: 541 FPKATDMTFKAKLYDNHLGKSNNFQKPRNIKGKQEAHFSLIHYAGTVDYNILGWLEKNKD 600
Query: 601 PLNETVVALYQKSSLKLMATLFSSYATADTGDSGKSKGGKKKGSSFQTVSALHRENLNKL 660
PLNETVVALYQKSSLKLMATLFSSYATADTGDSGKSKGGKKKGSSFQTVSALHRENLNKL
Sbjct: 601 PLNETVVALYQKSSLKLMATLFSSYATADTGDSGKSKGGKKKGSSFQTVSALHRENLNKL 660
Query: 661 MTNLRTTHPHFVRCIIPNERKAPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDF 720
MTNLRTTHPHFVRCIIPNERKAPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDF
Sbjct: 661 MTNLRTTHPHFVRCIIPNERKAPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDF 720
Query: 721 RQRYRILNPVAIPEGQFIDSRKGTEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRD 780
RQRYRILNPVAIPEGQFIDSRKGTEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRD
Sbjct: 721 RQRYRILNPVAIPEGQFIDSRKGTEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRD 780
Query: 781 ERLSRIITRMQAQARGQLMRIEFKKIVERRDALLVIQWNIRAFMGVKNWPWMKLYFKIKP 840
ERLSRIITRMQAQARGQLMRIEFKKIVERRDALLVIQWNIRAFMGVKNWPWMKLYFKIKP
Sbjct: 781 ERLSRIITRMQAQARGQLMRIEFKKIVERRDALLVIQWNIRAFMGVKNWPWMKLYFKIKP 840
Query: 841 LLKSAETEKEMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNL 900
LLKSAETEKEMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNL
Sbjct: 841 LLKSAETEKEMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNL 900
Query: 901 NDAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLE 960
NDAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLE
Sbjct: 901 NDAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLE 960
Query: 961 LTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQVEEDKVN 1020
LTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQVEEDKVN
Sbjct: 961 LTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQVEEDKVN 1020
Query: 1021 SLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEE 1080
SLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEE
Sbjct: 1021 SLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEE 1080
Query: 1081 KLKKKEFDINQQNSKIEDEQVLALQLQKKLKENQARIEELEEELEAERTARAKVEKLRSD 1140
KLKKKEFDINQQNSKIEDEQVLALQLQKKLKENQARIEELEEELEAERTARAKVEKLRSD
Sbjct: 1081 KLKKKEFDINQQNSKIEDEQVLALQLQKKLKENQARIEELEEELEAERTARAKVEKLRSD 1140
Query: 1141 LSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHAD 1200
LSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHAD
Sbjct: 1141 LSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHAD 1200
Query: 1201 SVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANE 1260
SVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANE
Sbjct: 1201 SVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANE 1260
Query: 1261 YRVKLEEAQRSLNDFTTQRAKLQTENGELARQLEEKEALISQLTRGKLSYTQQMEDLKRQ 1320
YRVKLEEAQRSLNDFTTQRAKLQTENGELARQLEEKEALISQLTRGKLSYTQQMEDLKRQ
Sbjct: 1261 YRVKLEEAQRSLNDFTTQRAKLQTENGELARQLEEKEALISQLTRGKLSYTQQMEDLKRQ 1320
Query: 1321 LEEEGKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETD 1380
LEEEGKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETD
Sbjct: 1321 LEEEGKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETD 1380
Query: 1381 AIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAA 1440
AIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAA
Sbjct: 1381 AIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAA 1440
Query: 1441 AAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETF 1500
AAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETF
Sbjct: 1441 AAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETF 1500
Query: 1501 KRENKNLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQSALEEAEASLEHEEGKI 1560
KRENKNLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQSALEEAEASLEHEEGKI
Sbjct: 1501 KRENKNLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQSALEEAEASLEHEEGKI 1560
Query: 1561 LRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKM 1620
LRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKM
Sbjct: 1561 LRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKM 1620
Query: 1621 EGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRN 1680
EGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRN
Sbjct: 1621 EGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRN 1680
Query: 1681 NLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMESDLTQLQ 1740
NLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMESDLTQLQ
Sbjct: 1681 NLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMESDLTQLQ 1740
Query: 1741 SEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLD 1800
SEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLD
Sbjct: 1741 SEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLD 1800
Query: 1801 EAEQIALKGGKKQLQKLEARVRELEGELEAEQKRNAESVKGMRKSERRIKELTYQTEEDK 1860
EAEQIALKGGKKQLQKLEARVRELEGELEAEQKRNAESVKGMRKSERRIKELTYQTEEDK
Sbjct: 1801 EAEQIALKGGKKQLQKLEARVRELEGELEAEQKRNAESVKGMRKSERRIKELTYQTEEDK 1860
Query: 1861 KNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVN 1920
KNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVN
Sbjct: 1861 KNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVN 1920
Query: 1921 KLRAKSRDIGAKQKMHDEE 1939
KLRAKSRDIGAKQKMHDEE
Sbjct: 1921 KLRAKSRDIGAKQKMHDEE 1939
>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
sapiens]
Length = 1935
Score = 3494 bits (9060), Expect = 0.0
Identities = 1796/1932 (92%), Positives = 1865/1932 (96%), Gaps = 2/1932 (0%)
Query: 1 MTDAQMADFGAAAQYLRKSEKERLEAQTRPFDIRTECFVPDDKEEFVKAKILSREGGKVI 60
M D++MA FGAAA YLRKSEKERLEAQTRPFD++ + FVPDDK+EFVKAKI+SREGGKV
Sbjct: 1 MGDSEMAVFGAAAPYLRKSEKERLEAQTRPFDLKKDVFVPDDKQEFVKAKIVSREGGKVT 60
Query: 61 AETENGKTVTVKEDQVLQQNPPKFDKIEDMAMLTFLHEPAVLFNLKERYAAWMIYTYSGL 120
AETE GKTVTVKEDQV+QQNPPKFDKIEDMAMLTFLHEPAVL+NLK+RY +WMIYTYSGL
Sbjct: 61 AETEYGKTVTVKEDQVMQQNPPKFDKIEDMAMLTFLHEPAVLYNLKDRYGSWMIYTYSGL 120
Query: 121 FCVTVNPYKWLPVYNAEVVAAYRGKKRSEAPPHIFSISDNAYQYMLTDRENQSILITGES 180
FCVTVNPYKWLPVY EVVAAYRGKKRSEAPPHIFSISDNAYQYMLTDRENQSILITGES
Sbjct: 121 FCVTVNPYKWLPVYTPEVVAAYRGKKRSEAPPHIFSISDNAYQYMLTDRENQSILITGES 180
Query: 181 GAGKTVNTKRVIQYFASIAAIGDRGKKDNANANKGTLEDQIIQANPALEAFGNAKTVRND 240
GAGKTVNTKRVIQYFA IAAIGDR KKD + KGTLEDQIIQANPALEAFGNAKTVRND
Sbjct: 181 GAGKTVNTKRVIQYFAVIAAIGDRSKKDQS-PGKGTLEDQIIQANPALEAFGNAKTVRND 239
Query: 241 NSSRFGKFIRIHFGATGKLASADIETYLLEKSRVIFQLKAERNYHIFYQILSNKKPELLD 300
NSSRFGKFIRIHFGATGKLASADIETYLLEKSRVIFQLKAER+YHIFYQILSNKKPELLD
Sbjct: 240 NSSRFGKFIRIHFGATGKLASADIETYLLEKSRVIFQLKAERDYHIFYQILSNKKPELLD 299
Query: 301 MLLVTNNPYDYAFVSQGEVSVASIDDSEELMATDSAFDVLGFTSEEKAGVYKLTGAIMHY 360
MLL+TNNPYDYAF+SQGE +VASIDD+EELMATD+AFDVLGFTSEEK +YKLTGAIMH+
Sbjct: 300 MLLITNNPYDYAFISQGETTVASIDDAEELMATDNAFDVLGFTSEEKNSMYKLTGAIMHF 359
Query: 361 GNMKFKQKQREEQAEPDGTEDADKSAYLMGLNSADLLKGLCHPRVKVGNEYVTKGQSVQQ 420
GNMKFK KQREEQAEPDGTE+ADKSAYLMGLNSADLLKGLCHPRVKVGNEYVTKGQ+VQQ
Sbjct: 360 GNMKFKLKQREEQAEPDGTEEADKSAYLMGLNSADLLKGLCHPRVKVGNEYVTKGQNVQQ 419
Query: 421 VYYSIGALAKAVYEKMFNWMVTRINATLETKQPRQYFIGVLDIAGFEIFDFNSFEQLCIN 480
V Y+ GALAKAVYE+MFNWMVTRINATLETKQPRQYFIGVLDIAGFEIFDFNSFEQLCIN
Sbjct: 420 VIYATGALAKAVYERMFNWMVTRINATLETKQPRQYFIGVLDIAGFEIFDFNSFEQLCIN 479
Query: 481 FTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLQACIDLIEKPMGIMSILEEECM 540
FTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLQACIDLIEKPMGIMSILEEECM
Sbjct: 480 FTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLQACIDLIEKPMGIMSILEEECM 539
Query: 541 FPKATDMTFKAKLYDNHLGKSNNFQKPRNIKGKQEAHFSLIHYAGTVDYNILGWLEKNKD 600
FPKATDMTFKAKL+DNHLGKS NFQKPRNIKGK EAHFSLIHYAG VDYNI+GWL+KNKD
Sbjct: 540 FPKATDMTFKAKLFDNHLGKSANFQKPRNIKGKPEAHFSLIHYAGIVDYNIIGWLQKNKD 599
Query: 601 PLNETVVALYQKSSLKLMATLFSSYATADTGDSGKSKGGKKKGSSFQTVSALHRENLNKL 660
PLNETVV LYQKSSLKL++TLF++YA AD K KG KKGSSFQTVSALHRENLNKL
Sbjct: 600 PLNETVVGLYQKSSLKLLSTLFANYAGADAPIE-KGKGKAKKGSSFQTVSALHRENLNKL 658
Query: 661 MTNLRTTHPHFVRCIIPNERKAPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDF 720
MTNLR+THPHFVRCIIPNE K+PGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDF
Sbjct: 659 MTNLRSTHPHFVRCIIPNETKSPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDF 718
Query: 721 RQRYRILNPVAIPEGQFIDSRKGTEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRD 780
RQRYRILNP AIPEGQFIDSRKG EKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRD
Sbjct: 719 RQRYRILNPAAIPEGQFIDSRKGAEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRD 778
Query: 781 ERLSRIITRMQAQARGQLMRIEFKKIVERRDALLVIQWNIRAFMGVKNWPWMKLYFKIKP 840
ERLSRIITR+QAQ+RG L R+E+KK++ERRD+LLVIQWNIRAFMGVKNWPWMKLYFKIKP
Sbjct: 779 ERLSRIITRIQAQSRGVLARMEYKKLLERRDSLLVIQWNIRAFMGVKNWPWMKLYFKIKP 838
Query: 841 LLKSAETEKEMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNL 900
LLKSAE EKEMA+MKEEF R+KE LEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNL
Sbjct: 839 LLKSAEREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNL 898
Query: 901 NDAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLE 960
DAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELK+DIDDLE
Sbjct: 899 ADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLE 958
Query: 961 LTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQVEEDKVN 1020
LTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQ EEDKVN
Sbjct: 959 LTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVN 1018
Query: 1021 SLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEE 1080
+L+K+KVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDK QL+E
Sbjct: 1019 TLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDE 1078
Query: 1081 KLKKKEFDINQQNSKIEDEQVLALQLQKKLKENQARIEELEEELEAERTARAKVEKLRSD 1140
+LKKK+F++N N++IEDEQ L QLQKKLKE QARIEELEEELEAERTARAKVEKLRSD
Sbjct: 1079 RLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSD 1138
Query: 1141 LSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHAD 1200
LSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHAD
Sbjct: 1139 LSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHAD 1198
Query: 1201 SVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANE 1260
SVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEK+ RTLEDQ NE
Sbjct: 1199 SVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNE 1258
Query: 1261 YRVKLEEAQRSLNDFTTQRAKLQTENGELARQLEEKEALISQLTRGKLSYTQQMEDLKRQ 1320
+R K EE QRS+ND T+QRAKLQTENGEL+RQL+EKEALISQLTRGKL+YTQQ+EDLKRQ
Sbjct: 1259 HRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQ 1318
Query: 1321 LEEEGKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETD 1380
LEEE KAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETD
Sbjct: 1319 LEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETD 1378
Query: 1381 AIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAA 1440
AIQRTEELEEAKKKLAQRLQ+AEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAA
Sbjct: 1379 AIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAA 1438
Query: 1441 AAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETF 1500
AAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETF
Sbjct: 1439 AAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETF 1498
Query: 1501 KRENKNLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQSALEEAEASLEHEEGKI 1560
KRENKNLQEEISDLTEQLG GK +HELEKVRKQLE EK+ELQSALEEAEASLEHEEGKI
Sbjct: 1499 KRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKI 1558
Query: 1561 LRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKM 1620
LRAQLEFNQIKAEIERKLAEKDEEMEQAKRNH RVVDSLQTSLDAETRSRNE LRVKKKM
Sbjct: 1559 LRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKM 1618
Query: 1621 EGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRN 1680
EGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRN
Sbjct: 1619 EGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRN 1678
Query: 1681 NLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMESDLTQLQ 1740
NLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKM++DL+QLQ
Sbjct: 1679 NLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQ 1738
Query: 1741 SEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLD 1800
+EVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLD
Sbjct: 1739 TEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLD 1798
Query: 1801 EAEQIALKGGKKQLQKLEARVRELEGELEAEQKRNAESVKGMRKSERRIKELTYQTEEDK 1860
EAEQIALKGGKKQLQKLEARVRELE ELEAEQKRNAESVKGMRKSERRIKELTYQTEED+
Sbjct: 1799 EAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDR 1858
Query: 1861 KNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVN 1920
KNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVN
Sbjct: 1859 KNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVN 1918
Query: 1921 KLRAKSRDIGAK 1932
KLRAKSRDIG K
Sbjct: 1919 KLRAKSRDIGTK 1930
Score = 66.2 bits (160), Expect = 3e-10
Identities = 85/385 (22%), Positives = 169/385 (43%), Gaps = 27/385 (7%)
Query: 1564 QLEFNQIKAEIERKLAEKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGD 1623
Q +F K + L EEM + + R++ T + A++R + KK +E
Sbjct: 755 QYKFGHTKVFFKAGLLGLLEEMRDERLS--RII----TRIQAQSRGVLARMEYKKLLERR 808
Query: 1624 LNEMEIQLSHANRMAAEAQKQVK---SLQSLLKDTQIQLDDAVRAND--DLKENIAIVER 1678
+ + IQ + M + +K ++ LLK + + + A + LKE + E
Sbjct: 809 DSLLVIQWNIRAFMGVKNWPWMKLYFKIKPLLKSAEREKEMASMKEEFTRLKEALEKSEA 868
Query: 1679 RNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMESDLTQ 1738
R L+ ++ L + + + L + ER LI K ++E+ + +
Sbjct: 869 RRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCD-------QLIKNKIQLEAKVKE 921
Query: 1739 LQSEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQD----TSAHLERMKKNMEQTIKD 1794
+ +E+ +E NAE AKK + ELK++ D T A +E+ K E +K+
Sbjct: 922 MNERLED--EEEMNAELTAKKRKLEDE--CSELKRDIDDLELTLAKVEKEKHATENKVKN 977
Query: 1795 LQHRLDEAEQIALKGGKKQLQKLEARVRELEGELEAEQKRNAESVKGMRKSERRIKELTY 1854
L + ++I K K++ EA + L+ +L+AE+ + K K E+++ +L
Sbjct: 978 LTEEMAGLDEIIAKLTKEKKALQEAHQQALD-DLQAEEDKVNTLTKAKVKLEQQVDDLEG 1036
Query: 1855 QTEEDKKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADI 1914
E++KK + L+ KL+ +K + + E + +K EL+ R +
Sbjct: 1037 SLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIED 1096
Query: 1915 AESQVNKLRAKSRDIGAKQKMHDEE 1939
++ ++L+ K +++ A+ + +EE
Sbjct: 1097 EQALGSQLQKKLKELQARIEELEEE 1121
Score = 36.2 bits (82), Expect = 0.32
Identities = 38/134 (28%), Positives = 63/134 (47%), Gaps = 19/134 (14%)
Query: 862 KETLEKSEARRKELEEKMVSLLQ------------EKNDLQLQVQAEQDNLNDAEERCDQ 909
K+ L+K EAR +ELE ++ + + E+ +L Q E+D N R
Sbjct: 1809 KKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLL--RLQD 1866
Query: 910 LIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKE 969
L+ +K+QL KVK + E+ EE +K RK++ E E ++ D E + K+ +
Sbjct: 1867 LV-DKLQL--KVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAK 1923
Query: 970 KHATENKVKNLTEE 983
+ + K L EE
Sbjct: 1924 --SRDIGTKGLNEE 1935
>gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo
sapiens]
Length = 1939
Score = 3122 bits (8093), Expect = 0.0
Identities = 1557/1932 (80%), Positives = 1756/1932 (90%), Gaps = 1/1932 (0%)
Query: 2 TDAQMADFGAAAQYLRKSEKERLEAQTRPFDIRTECFVPDDKEEFVKAKILSREGGKVIA 61
+D++MA FG AA +LRKSE+ER+EAQ +PFD +T FV D KE FVKA + SREGGKV A
Sbjct: 3 SDSEMAIFGEAAPFLRKSERERIEAQNKPFDAKTSVFVVDPKESFVKATVQSREGGKVTA 62
Query: 62 ETENGKTVTVKEDQVLQQNPPKFDKIEDMAMLTFLHEPAVLFNLKERYAAWMIYTYSGLF 121
+TE G TVTVK+DQV NPPK+DKIEDMAM+T LHEPAVL+NLKERYAAWMIYTYSGLF
Sbjct: 63 KTEAGATVTVKDDQVFPMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLF 122
Query: 122 CVTVNPYKWLPVYNAEVVAAYRGKKRSEAPPHIFSISDNAYQYMLTDRENQSILITGESG 181
CVTVNPYKWLPVYNAEVV AYRGKKR EAPPHIFSISDNAYQ+MLTDRENQSILITGESG
Sbjct: 123 CVTVNPYKWLPVYNAEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESG 182
Query: 182 AGKTVNTKRVIQYFASIAAIGDRGKKDNANAN-KGTLEDQIIQANPALEAFGNAKTVRND 240
AGKTVNTKRVIQYFA+IA G++ K++ + +GTLEDQII ANP LEAFGNAKTVRND
Sbjct: 183 AGKTVNTKRVIQYFATIAVTGEKKKEEVTSGKMQGTLEDQIISANPLLEAFGNAKTVRND 242
Query: 241 NSSRFGKFIRIHFGATGKLASADIETYLLEKSRVIFQLKAERNYHIFYQILSNKKPELLD 300
NSSRFGKFIRIHFG TGKLASADIETYLLEKSRV FQLKAER+YHIFYQI+SNKKP+L++
Sbjct: 243 NSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQIMSNKKPDLIE 302
Query: 301 MLLVTNNPYDYAFVSQGEVSVASIDDSEELMATDSAFDVLGFTSEEKAGVYKLTGAIMHY 360
MLL+T NPYDYAFVSQGE++V SIDD EELMATDSA ++LGFTS+E+ +YKLTGA+MHY
Sbjct: 303 MLLITTNPYDYAFVSQGEITVPSIDDQEELMATDSAIEILGFTSDERVSIYKLTGAVMHY 362
Query: 361 GNMKFKQKQREEQAEPDGTEDADKSAYLMGLNSADLLKGLCHPRVKVGNEYVTKGQSVQQ 420
GNMKFKQKQREEQAEPDGTE ADK+AYL LNSADLLK LC+PRVKVGNEYVTKGQ+VQQ
Sbjct: 363 GNMKFKQKQREEQAEPDGTEVADKAAYLQNLNSADLLKALCYPRVKVGNEYVTKGQTVQQ 422
Query: 421 VYYSIGALAKAVYEKMFNWMVTRINATLETKQPRQYFIGVLDIAGFEIFDFNSFEQLCIN 480
VY ++GALAKAVY+KMF WMVTRIN L+TKQPRQYFIGVLDIAGFEIFDFNS EQLCIN
Sbjct: 423 VYNAVGALAKAVYDKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCIN 482
Query: 481 FTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLQACIDLIEKPMGIMSILEEECM 540
FTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDL ACI+LIEKPMGI SILEEECM
Sbjct: 483 FTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEECM 542
Query: 541 FPKATDMTFKAKLYDNHLGKSNNFQKPRNIKGKQEAHFSLIHYAGTVDYNILGWLEKNKD 600
FPKATD +FK KLY+ HLGKSNNFQKP+ KGK EAHFSLIHYAGTVDYNI GWL+KNKD
Sbjct: 543 FPKATDTSFKNKLYEQHLGKSNNFQKPKPAKGKPEAHFSLIHYAGTVDYNIAGWLDKNKD 602
Query: 601 PLNETVVALYQKSSLKLMATLFSSYATADTGDSGKSKGGKKKGSSFQTVSALHRENLNKL 660
PLNETVV LYQKS++K +A LF A+ G KGGKKKGSSFQTVSAL RENLNKL
Sbjct: 603 PLNETVVGLYQKSAMKTLALLFVGATGAEAEAGGGKKGGKKKGSSFQTVSALFRENLNKL 662
Query: 661 MTNLRTTHPHFVRCIIPNERKAPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDF 720
MTNLR+THPHFVRCIIPNE K PG M++ LV+HQLRCNGVLEGIRICRKGFP+RILY DF
Sbjct: 663 MTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADF 722
Query: 721 RQRYRILNPVAIPEGQFIDSRKGTEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRD 780
+QRY++LN AIPEGQFIDS+K +EKLL S+DIDH QYKFGHTKVFFKAGLLGLLEEMRD
Sbjct: 723 KQRYKVLNASAIPEGQFIDSKKASEKLLGSIDIDHTQYKFGHTKVFFKAGLLGLLEEMRD 782
Query: 781 ERLSRIITRMQAQARGQLMRIEFKKIVERRDALLVIQWNIRAFMGVKNWPWMKLYFKIKP 840
E+L+++ITR QA RG L R+E++K+VERR+++ IQ+N+RAFM VK+WPWMKLYFKIKP
Sbjct: 783 EKLAQLITRTQAMCRGFLARVEYQKMVERRESIFCIQYNVRAFMNVKHWPWMKLYFKIKP 842
Query: 841 LLKSAETEKEMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNL 900
LLKSAETEKEMA MKEEF + KE L K+EA+RKELEEKMV+L+QEKNDLQLQVQAE D+L
Sbjct: 843 LLKSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADSL 902
Query: 901 NDAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLE 960
DAEERCDQLIK KIQLEAK+KE+ ER EDEEE+NAELTAKKRKLEDECSELKKDIDDLE
Sbjct: 903 ADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLE 962
Query: 961 LTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQVEEDKVN 1020
LTLAKVEKEKHATENKVKNLTEEMAGLDE IAKLTKEKKALQEAHQQ LDDLQ EEDKVN
Sbjct: 963 LTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVN 1022
Query: 1021 SLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEE 1080
+L+K+K+KLEQQVDDLEGSLEQEKK+RMDLERAKRKLEGDLKL QES MD+ENDK QL+E
Sbjct: 1023 TLTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDLKLAQESTMDIENDKQQLDE 1082
Query: 1081 KLKKKEFDINQQNSKIEDEQVLALQLQKKLKENQARIEELEEELEAERTARAKVEKLRSD 1140
KLKKKEF+++ SKIEDEQ L +QLQKK+KE QARIEELEEE+EAER +RAK EK RSD
Sbjct: 1083 KLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSD 1142
Query: 1141 LSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHAD 1200
LSRELEEISERLEEAGGATS QIEMNKKREAEFQKMRRDLEEATLQHEATAA LRKKHAD
Sbjct: 1143 LSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHAD 1202
Query: 1201 SVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANE 1260
SVAELGEQIDNLQRVKQKLEKEKSE K+E+DD+ SNME + KAK NLEK+ R LEDQ +E
Sbjct: 1203 SVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQLSE 1262
Query: 1261 YRVKLEEAQRSLNDFTTQRAKLQTENGELARQLEEKEALISQLTRGKLSYTQQMEDLKRQ 1320
+ K EE QR +ND T QRA+LQTE+GE +RQL+EK+ L+SQL+RGK ++TQQ+E+LKRQ
Sbjct: 1263 IKTKEEEQQRLINDLTAQRARLQTESGEYSRQLDEKDTLVSQLSRGKQAFTQQIEELKRQ 1322
Query: 1321 LEEEGKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETD 1380
LEEE KAK+ALAHALQS+RHDCDLLREQYEEE EAKAELQR +SKANSEVAQWRTKYETD
Sbjct: 1323 LEEEIKAKSALAHALQSSRHDCDLLREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETD 1382
Query: 1381 AIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAA 1440
AIQRTEELEEAKKKLAQRLQDAEE VEAVNAKC+SLEKTK RLQNE+EDLM+DVER+NAA
Sbjct: 1383 AIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAA 1442
Query: 1441 AAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETF 1500
AALDKKQRNFDKILAEWKQK EE+ +ELE+SQKE+RSLSTELFK+KNAYEESL+ LET
Sbjct: 1443 CAALDKKQRNFDKILAEWKQKCEETHAELEASQKESRSLSTELFKIKNAYEESLDQLETL 1502
Query: 1501 KRENKNLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQSALEEAEASLEHEEGKI 1560
KRENKNLQ+EISDLTEQ+ EGGK +HELEK++KQ+E EK ELQ+ALEEAEASLEHEEGKI
Sbjct: 1503 KRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKSELQAALEEAEASLEHEEGKI 1562
Query: 1561 LRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKM 1620
LR QLE NQ+K+E++RK+AEKDEE++Q KRNH R+V+S+Q++LDAE RSRN+ +R+KKKM
Sbjct: 1563 LRIQLELNQVKSEVDRKIAEKDEEIDQMKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKM 1622
Query: 1621 EGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRN 1680
EGDLNEMEIQL+HANRMAAEA + ++ Q++LKDTQ+ LDDA+R+ +DLKE +A+VERR
Sbjct: 1623 EGDLNEMEIQLNHANRMAAEALRNYRNTQAILKDTQLHLDDALRSQEDLKEQLAMVERRA 1682
Query: 1681 NLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMESDLTQLQ 1740
NLLQAE+EELRA +EQTERSRK+AEQEL++ SERVQLLH+QNTSLIN KKK+E+D++Q+Q
Sbjct: 1683 NLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQ 1742
Query: 1741 SEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLD 1800
E+E+ +QE RNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKN+EQT+KDLQHRLD
Sbjct: 1743 GEMEDIIQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLD 1802
Query: 1801 EAEQIALKGGKKQLQKLEARVRELEGELEAEQKRNAESVKGMRKSERRIKELTYQTEEDK 1860
EAEQ+ALKGGKKQ+QKLEARVRELEGE+E+EQKRN E+VKG+RK ER++KELTYQTEED+
Sbjct: 1803 EAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNVEAVKGLRKHERKVKELTYQTEEDR 1862
Query: 1861 KNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVN 1920
KN+LRLQDLVDKLQ KVK+YKRQAEEAEEQ+N NLSKFR++QHEL+EAEERADIAESQVN
Sbjct: 1863 KNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNVNLSKFRRIQHELEEAEERADIAESQVN 1922
Query: 1921 KLRAKSRDIGAK 1932
KLR KSR++ K
Sbjct: 1923 KLRVKSREVHTK 1934
Score = 188 bits (477), Expect = 5e-47
Identities = 193/848 (22%), Positives = 372/848 (43%), Gaps = 100/848 (11%)
Query: 832 MKLYFKIKPLLKSAETEKEMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQL 891
M+L KIK L E E E E R K ++S+ R ELEE L +
Sbjct: 1106 MQLQKKIKELQARIE-ELEEEIEAERASRAKAEKQRSDLSR-ELEEISERLEEAGGATSA 1163
Query: 892 QVQAEQDNLNDAEERCDQLIKNKIQLEAKVKEMNERLEDEE----EMNAELTAKKRKLED 947
Q++ + + ++ L + +Q EA + ++ D E L K+KLE
Sbjct: 1164 QIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEK 1223
Query: 948 ECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGL-------DEIIAKLTKEKKA 1000
E SE+K +IDDL + V K K E + L ++++ + +I LT ++
Sbjct: 1224 EKSEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQRLINDLTAQRAR 1283
Query: 1001 LQEAHQQALDDLQVEEDKVNSLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGD 1060
LQ + L ++ V+ LS+ K QQ+++L+ LE+E K + L A + D
Sbjct: 1284 LQTESGEYSRQLDEKDTLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSSRHD 1343
Query: 1061 LKLTQESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQVLALQ-LQKKLKENQARIEE 1119
L +E + + K +L+ + K ++ Q +K E + + + L++ K+ R+++
Sbjct: 1344 CDLLREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQD 1403
Query: 1120 LEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRD 1179
EE +EA A +EK + L E+E++ +E A + K++ F K+ +
Sbjct: 1404 AEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAAL----DKKQRNFDKILAE 1459
Query: 1180 LEEATLQHEATAAALRKKHADSVAEL-------GEQIDNLQRVKQKLEKEKSEFKLELDD 1232
++ + A A +K+ EL E +D L+ +K +E + E+ D
Sbjct: 1460 WKQKCEETHAELEASQKESRSLSTELFKIKNAYEESLDQLETLK----RENKNLQQEISD 1515
Query: 1233 VTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQTE----NGE 1288
+T + + K LEK+ + +E + +E + LEEA+ SL + ++Q E E
Sbjct: 1516 LTEQIAEGGKRIHELEKIKKQVEQEKSELQAALEEAEASLEHEEGKILRIQLELNQVKSE 1575
Query: 1289 LARQLEEKEALISQLTRGKLSYTQQMED--------------LKRQLEEE--------GK 1326
+ R++ EK+ I Q+ R + + M+ LK+++E +
Sbjct: 1576 VDRKIAEKDEEIDQMKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNH 1635
Query: 1327 AKNALAHALQSARHDCDLLREQY-------EEETEAKAELQRVLSKANSEVAQWRTKYET 1379
A A AL++ R+ +L++ + + K +L V +AN A E
Sbjct: 1636 ANRMAAEALRNYRNTQAILKDTQLHLDDALRSQEDLKEQLAMVERRANLLQA------EI 1689
Query: 1380 DAIQRTEELEEAKKKLA-QRLQDAEEAVEAVNAKCSSLEKTKHRL-------QNEIEDLM 1431
+ ++ T E E +K+A Q L DA E V+ ++ + +SL TK +L Q E+ED++
Sbjct: 1690 EELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDII 1749
Query: 1432 VDVERSNAAA---------------------AALDKKQRNFDKILAEWKQKYEES-QSEL 1469
+ + A A L++ ++N ++ + + + + +E+ Q L
Sbjct: 1750 QEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLAL 1809
Query: 1470 ESSQKEARSLSTELFKLKNAYE-ESLEHLETFKRENKNLQEEISDLTEQLGEGGKNVHEL 1528
+ +K+ + L + +L+ E E ++E K K+ + ++ +LT Q E KN+ L
Sbjct: 1810 KGGKKQIQKLEARVRELEGEVESEQKRNVEAVKGLRKH-ERKVKELTYQTEEDRKNILRL 1868
Query: 1529 EKVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQA 1588
+ + +L+ + + EEAE K R Q E + + + ++ ++ ++
Sbjct: 1869 QDLVDKLQAKVKSYKRQAEEAEEQSNVNLSKFRRIQHELEEAEERADIAESQVNKLRVKS 1928
Query: 1589 KRNHQRVV 1596
+ H +++
Sbjct: 1929 REVHTKII 1936
Score = 66.2 bits (160), Expect = 3e-10
Identities = 64/313 (20%), Positives = 139/313 (44%), Gaps = 44/313 (14%)
Query: 1638 AAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKEN-IAIVERRNNL---LQAELEELRAV 1693
+AE +K++ +++ + T+ +L +L+E + +++ +N+L +QAE + L
Sbjct: 846 SAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADSLADA 905
Query: 1694 VEQTERSRKLA---EQELIETSERVQLLHSQNTSLINQKKKMESDLTQLQSEVEEAVQEC 1750
E+ ++ K E ++ E +ER + N L +K+K+E + ++L+ ++++
Sbjct: 906 EERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTL 965
Query: 1751 RNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNME----QTIKDLQHRLDEAEQIA 1806
E++ + EE+ +T A L + KK ++ QT+ DLQ D+ +
Sbjct: 966 AKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLT 1025
Query: 1807 LKGGKKQLQKLEARVRELEGELEAEQKRNAESVKGMRKSERRIKELTYQTEEDKKNLLRL 1866
K KLE +V +LEG L E++KK + L
Sbjct: 1026 -----KAKIKLEQQVDDLEGSL----------------------------EQEKKIRMDL 1052
Query: 1867 QDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKS 1926
+ KL+ +K + + E K +K + E+ + + + ++ +L+ K
Sbjct: 1053 ERAKRKLEGDLKLAQESTMDIENDKQQLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKI 1112
Query: 1927 RDIGAKQKMHDEE 1939
+++ A+ + +EE
Sbjct: 1113 KELQARIEELEEE 1125
Score = 33.1 bits (74), Expect = 2.7
Identities = 24/99 (24%), Positives = 46/99 (46%), Gaps = 4/99 (4%)
Query: 838 IKPLLKSAETEKEMATMKEE----FGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQV 893
+K L K KE+ EE R+++ ++K +A+ K + + ++ N +
Sbjct: 1841 VKGLRKHERKVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNVNLSKF 1900
Query: 894 QAEQDNLNDAEERCDQLIKNKIQLEAKVKEMNERLEDEE 932
+ Q L +AEER D +L K +E++ ++ EE
Sbjct: 1901 RRIQHELEEAEERADIAESQVNKLRVKSREVHTKIISEE 1939
>gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 3108 bits (8058), Expect = 0.0
Identities = 1558/1934 (80%), Positives = 1754/1934 (90%), Gaps = 3/1934 (0%)
Query: 2 TDAQMADFGAAAQYLRKSEKERLEAQTRPFDIRTECFVPDDKEEFVKAKILSREGGKVIA 61
+D+++A FG AA +LRKSE+ER+EAQ RPFD +T FV + KE FVK I SREGGKV
Sbjct: 3 SDSELAVFGEAAPFLRKSERERIEAQNRPFDAKTSVFVAEPKESFVKGTIQSREGGKVTV 62
Query: 62 ETENGKTVTVKEDQVLQQNPPKFDKIEDMAMLTFLHEPAVLFNLKERYAAWMIYTYSGLF 121
+TE G T+TVK+DQV NPPK+DKIEDMAM+T LHEPAVL+NLKERYAAWMIYTYSGLF
Sbjct: 63 KTEGGATLTVKDDQVFPMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLF 122
Query: 122 CVTVNPYKWLPVYNAEVVAAYRGKKRSEAPPHIFSISDNAYQYMLTDRENQSILITGESG 181
CVTVNPYKWLPVY EVV AYRGKKR EAPPHIFSISDNAYQ+MLTDRENQSILITGESG
Sbjct: 123 CVTVNPYKWLPVYKPEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESG 182
Query: 182 AGKTVNTKRVIQYFASIAAIGDRGKKDNANAN-KGTLEDQIIQANPALEAFGNAKTVRND 240
AGKTVNTKRVIQYFA+IA G++ K++ + +GTLEDQII ANP LEAFGNAKTVRND
Sbjct: 183 AGKTVNTKRVIQYFATIAVTGEKKKEEITSGKIQGTLEDQIISANPLLEAFGNAKTVRND 242
Query: 241 NSSRFGKFIRIHFGATGKLASADIETYLLEKSRVIFQLKAERNYHIFYQILSNKKPELLD 300
NSSRFGKFIRIHFG TGKLASADIETYLLEKSRV+FQLKAER+YHIFYQI SNKKPEL++
Sbjct: 243 NSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVVFQLKAERSYHIFYQITSNKKPELIE 302
Query: 301 MLLVTNNPYDYAFVSQGEVSVASIDDSEELMATDSAFDVLGFTSEEKAGVYKLTGAIMHY 360
MLL+T NPYDY FVSQGE+SVASIDD EELMATDSA D+LGFT+EEK +YKLTGA+MHY
Sbjct: 303 MLLITTNPYDYPFVSQGEISVASIDDQEELMATDSAIDILGFTNEEKVSIYKLTGAVMHY 362
Query: 361 GNMKFKQKQREEQAEPDGTEDADKSAYLMGLNSADLLKGLCHPRVKVGNEYVTKGQSVQQ 420
GN+KFKQKQREEQAEPDGTE ADK+AYL LNSADLLK LC+PRVKVGNEYVTKGQ+V+Q
Sbjct: 363 GNLKFKQKQREEQAEPDGTEVADKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTVEQ 422
Query: 421 VYYSIGALAKAVYEKMFNWMVTRINATLETKQPRQYFIGVLDIAGFEIFDFNSFEQLCIN 480
V ++GALAKAVYEKMF WMV RIN L+TKQPRQYFIGVLDIAGFEIFDFNS EQLCIN
Sbjct: 423 VSNAVGALAKAVYEKMFLWMVARINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCIN 482
Query: 481 FTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLQACIDLIEKPMGIMSILEEECM 540
FTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDL ACI+LIEKPMGI SILEEECM
Sbjct: 483 FTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEECM 542
Query: 541 FPKATDMTFKAKLYDNHLGKSNNFQKPRNIKGKQEAHFSLIHYAGTVDYNILGWLEKNKD 600
FPKATD +FK KLYD HLGKS NFQKP+ +KGK EAHF+LIHYAG VDYNI GWLEKNKD
Sbjct: 543 FPKATDTSFKNKLYDQHLGKSANFQKPKVVKGKAEAHFALIHYAGVVDYNITGWLEKNKD 602
Query: 601 PLNETVVALYQKSSLKLMATLFSSYATADT--GDSGKSKGGKKKGSSFQTVSALHRENLN 658
PLNETVV LYQKS++K +A LFS TA+ G KGGKKKGSSFQTVSAL RENLN
Sbjct: 603 PLNETVVGLYQKSAMKTLAQLFSGAQTAEGEGAGGGAKKGGKKKGSSFQTVSALFRENLN 662
Query: 659 KLMTNLRTTHPHFVRCIIPNERKAPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYG 718
KLMTNLR+THPHFVRCIIPNE K PG M++ LV+HQLRCNGVLEGIRICRKGFP+RILY
Sbjct: 663 KLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYA 722
Query: 719 DFRQRYRILNPVAIPEGQFIDSRKGTEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEM 778
DF+QRY++LN AIPEGQFIDS+K +EKLL+S+DIDH QYKFGHTKVFFKAGLLGLLEEM
Sbjct: 723 DFKQRYKVLNASAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEM 782
Query: 779 RDERLSRIITRMQAQARGQLMRIEFKKIVERRDALLVIQWNIRAFMGVKNWPWMKLYFKI 838
RD++L+++ITR QA+ RG L R+E++++VERR+A+ IQ+NIR+FM VK+WPWMKL+FKI
Sbjct: 783 RDDKLAQLITRTQARCRGFLARVEYQRMVERREAIFCIQYNIRSFMNVKHWPWMKLFFKI 842
Query: 839 KPLLKSAETEKEMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQD 898
KPLLKSAETEKEMATMKEEF +IK+ L KSEA+RKELEEKMV+LL+EKNDLQLQVQAE +
Sbjct: 843 KPLLKSAETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAE 902
Query: 899 NLNDAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDIDD 958
L DAEERCDQLIK KIQLEAK+KE+ ER EDEEE+NAELTAKKRKLEDECSELKKDIDD
Sbjct: 903 GLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDD 962
Query: 959 LELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQVEEDK 1018
LELTLAKVEKEKHATENKVKNLTEEMAGLDE IAKLTKEKKALQEAHQQ LDDLQ EEDK
Sbjct: 963 LELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDK 1022
Query: 1019 VNSLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQL 1078
VN+L+K+K+KLEQQVDDLEGSLEQEKK+RMDLERAKRKLEGDLKL QESIMD+EN+K QL
Sbjct: 1023 VNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQL 1082
Query: 1079 EEKLKKKEFDINQQNSKIEDEQVLALQLQKKLKENQARIEELEEELEAERTARAKVEKLR 1138
+EKLKKKEF+I+ SKIEDEQ L +QLQKK+KE QARIEELEEE+EAER +RAK EK R
Sbjct: 1083 DEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQR 1142
Query: 1139 SDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKH 1198
SDLSRELEEISERLEEAGGATS QIEMNKKREAEFQKMRRDLEEATLQHEATAA LRKKH
Sbjct: 1143 SDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKH 1202
Query: 1199 ADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQA 1258
ADSVAELGEQIDNLQRVKQKLEKEKSE K+E+DD+ SN+E + KAK NLEK+ RTLEDQ
Sbjct: 1203 ADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQL 1262
Query: 1259 NEYRVKLEEAQRSLNDFTTQRAKLQTENGELARQLEEKEALISQLTRGKLSYTQQMEDLK 1318
+E + K EE QR +ND T QR +LQTE+GE +RQL+EKEAL+SQL+RGK ++TQQ+E+LK
Sbjct: 1263 SELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELK 1322
Query: 1319 RQLEEEGKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYE 1378
RQLEEE KAKNALAHALQS+RHDCDLLREQYEEE E+KAELQR LSKAN+EVAQWRTKYE
Sbjct: 1323 RQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYE 1382
Query: 1379 TDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSN 1438
TDAIQRTEELEEAKKKLAQRLQ AEE VEAVNAKC+SLEKTK RLQNE+EDLM+DVER+N
Sbjct: 1383 TDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTN 1442
Query: 1439 AAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLE 1498
AA AALDKKQRNFDKILAEWKQK EE+ +ELE+SQKEARSL TELFK+KNAYEESL+ LE
Sbjct: 1443 AACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLE 1502
Query: 1499 TFKRENKNLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQSALEEAEASLEHEEG 1558
T KRENKNLQ+EISDLTEQ+ EGGK +HELEK++KQ+E EK ELQ+ALEEAEASLEHEEG
Sbjct: 1503 TLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEG 1562
Query: 1559 KILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKK 1618
KILR QLE NQ+K+E++RK+AEKDEE++Q KRNH R+V+S+Q++LDAE RSRN+ +R+KK
Sbjct: 1563 KILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKK 1622
Query: 1619 KMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVER 1678
KMEGDLNEMEIQL+HANRMAAEA + ++ Q +LKDTQI LDDA+R+ +DLKE +A+VER
Sbjct: 1623 KMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVER 1682
Query: 1679 RNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMESDLTQ 1738
R NLLQAE+EELRA +EQTERSRK+AEQEL++ SERVQLLH+QNTSLIN KKK+E+D++Q
Sbjct: 1683 RANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQ 1742
Query: 1739 LQSEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHR 1798
+Q E+E+ +QE RNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQT+KDLQ R
Sbjct: 1743 MQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLR 1802
Query: 1799 LDEAEQIALKGGKKQLQKLEARVRELEGELEAEQKRNAESVKGMRKSERRIKELTYQTEE 1858
LDEAEQ+ALKGGKKQ+QKLEARVRELEGE+E+EQKRNAE+VKG+RK ERR+KELTYQTEE
Sbjct: 1803 LDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEE 1862
Query: 1859 DKKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQ 1918
D+KN+LRLQDLVDKLQ KVK+YKRQAEEAEEQ+NTNL+KFRK+QHEL+EAEERADIAESQ
Sbjct: 1863 DRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAESQ 1922
Query: 1919 VNKLRAKSRDIGAK 1932
VNKLR KSR++ K
Sbjct: 1923 VNKLRVKSREVHTK 1936
Score = 187 bits (475), Expect = 9e-47
Identities = 197/868 (22%), Positives = 377/868 (43%), Gaps = 121/868 (13%)
Query: 833 KLYFKIKPLLKSAETEKEMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQ---EKNDL 889
K F+I L E E+ + ++ +IKE + E +E+E + S + +++DL
Sbjct: 1088 KKEFEISNLQSKIEDEQALGIQLQK--KIKELQARIEELEEEIEAERASRAKAEKQRSDL 1145
Query: 890 QLQVQAEQDNLNDAEERCDQLIKNKIQLEAKVKEMNERLED----EEEMNAELTAK---- 941
+++ + L +A I+ + EA+ ++M LE+ E A L K
Sbjct: 1146 SRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADS 1205
Query: 942 --------------KRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGL 987
K+KLE E SE+K +IDDL + V K K E + L ++++ L
Sbjct: 1206 VAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSEL 1265
Query: 988 -------DEIIAKLTKEKKALQEAHQQALDDLQVEEDKVNSLSKSKVKLEQQVDDLEGSL 1040
+I LT ++ LQ + L +E V+ LS+ K QQ+++L+ L
Sbjct: 1266 KSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQL 1325
Query: 1041 EQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQ 1100
E+E K + L A + D L +E + + K +L+ L K ++ Q +K E +
Sbjct: 1326 EEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDA 1385
Query: 1101 VLALQ-LQKKLKENQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGAT 1159
+ + L++ K+ R++ EE +EA A +EK + L E+E++ +E A
Sbjct: 1386 IQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAAC 1445
Query: 1160 SVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAEL-------GEQIDNL 1212
+ K++ F K+ + ++ + A A +K+ EL E +D L
Sbjct: 1446 AAL----DKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQL 1501
Query: 1213 QRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRSL 1272
+ +K +E + E+ D+T + + K LEK+ + +E + E + LEEA+ SL
Sbjct: 1502 ETLK----RENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASL 1557
Query: 1273 NDFTTQRAKLQTE----NGELARQLEEKEALISQLTRGKLSYTQQMED------------ 1316
+ ++Q E E+ R++ EK+ I QL R + + M+
Sbjct: 1558 EHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDA 1617
Query: 1317 --LKRQLEEE--------GKAKNALAHALQSARHDCDLLREQY-------EEETEAKAEL 1359
LK+++E + A A AL++ R+ +L++ + + K +L
Sbjct: 1618 IRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQL 1677
Query: 1360 QRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLA-QRLQDAEEAVEAVNAKCSSLEK 1418
V +AN A E + ++ T E E +K+A Q L DA E V+ ++ + +SL
Sbjct: 1678 AMVERRANLLQA------EIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLIN 1731
Query: 1419 TKHRL-------QNEIEDLMVDVERSNAAA---------------------AALDKKQRN 1450
TK +L Q E+ED++ + + A A L++ ++N
Sbjct: 1732 TKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKN 1791
Query: 1451 FDKILAEWKQKYEES-QSELESSQKEARSLSTELFKLKNAYE-ESLEHLETFKRENKNLQ 1508
++ + + + + +E+ Q L+ +K+ + L + +L+ E E + E K K+ +
Sbjct: 1792 MEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKH-E 1850
Query: 1509 EEISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFN 1568
+ +LT Q E KN+ L+ + +L+ + + EEAE K + Q E
Sbjct: 1851 RRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELE 1910
Query: 1569 QIKAEIERKLAEKDEEMEQAKRNHQRVV 1596
+ + + ++ ++ +++ H +V+
Sbjct: 1911 EAEERADIAESQVNKLRVKSREVHTKVI 1938
Score = 65.1 bits (157), Expect = 6e-10
Identities = 62/313 (19%), Positives = 137/313 (43%), Gaps = 44/313 (14%)
Query: 1638 AAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELE-ELRAVVEQ 1696
+AE +K++ +++ + + +L + +L+E + + + N LQ +++ E + +
Sbjct: 848 SAETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADA 907
Query: 1697 TERSRKLA------EQELIETSERVQLLHSQNTSLINQKKKMESDLTQLQSEVEEAVQEC 1750
ER +L E ++ E +ER + N L +K+K+E + ++L+ ++++
Sbjct: 908 EERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTL 967
Query: 1751 RNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNME----QTIKDLQHRLDEAEQIA 1806
E++ + EE+ +T A L + KK ++ QT+ DLQ D+ +
Sbjct: 968 AKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLT 1027
Query: 1807 LKGGKKQLQKLEARVRELEGELEAEQKRNAESVKGMRKSERRIKELTYQTEEDKKNLLRL 1866
K KLE +V +LEG L E++KK + L
Sbjct: 1028 -----KAKIKLEQQVDDLEGSL----------------------------EQEKKLRMDL 1054
Query: 1867 QDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKS 1926
+ KL+ +K + + E + K +K + E+ + + + ++ +L+ K
Sbjct: 1055 ERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKI 1114
Query: 1927 RDIGAKQKMHDEE 1939
+++ A+ + +EE
Sbjct: 1115 KELQARIEELEEE 1127
Score = 33.9 bits (76), Expect = 1.6
Identities = 24/99 (24%), Positives = 46/99 (46%), Gaps = 4/99 (4%)
Query: 838 IKPLLKSAETEKEMATMKEE----FGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQV 893
+K L K KE+ EE R+++ ++K +A+ K + + ++ N +
Sbjct: 1843 VKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKF 1902
Query: 894 QAEQDNLNDAEERCDQLIKNKIQLEAKVKEMNERLEDEE 932
+ Q L +AEER D +L K +E++ ++ EE
Sbjct: 1903 RKLQHELEEAEERADIAESQVNKLRVKSREVHTKVISEE 1941
>gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 3108 bits (8058), Expect = 0.0
Identities = 1558/1934 (80%), Positives = 1754/1934 (90%), Gaps = 3/1934 (0%)
Query: 2 TDAQMADFGAAAQYLRKSEKERLEAQTRPFDIRTECFVPDDKEEFVKAKILSREGGKVIA 61
+D+++A FG AA +LRKSE+ER+EAQ RPFD +T FV + KE FVK I SREGGKV
Sbjct: 3 SDSELAVFGEAAPFLRKSERERIEAQNRPFDAKTSVFVAEPKESFVKGTIQSREGGKVTV 62
Query: 62 ETENGKTVTVKEDQVLQQNPPKFDKIEDMAMLTFLHEPAVLFNLKERYAAWMIYTYSGLF 121
+TE G T+TVK+DQV NPPK+DKIEDMAM+T LHEPAVL+NLKERYAAWMIYTYSGLF
Sbjct: 63 KTEGGATLTVKDDQVFPMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLF 122
Query: 122 CVTVNPYKWLPVYNAEVVAAYRGKKRSEAPPHIFSISDNAYQYMLTDRENQSILITGESG 181
CVTVNPYKWLPVY EVV AYRGKKR EAPPHIFSISDNAYQ+MLTDRENQSILITGESG
Sbjct: 123 CVTVNPYKWLPVYKPEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESG 182
Query: 182 AGKTVNTKRVIQYFASIAAIGDRGKKDNANAN-KGTLEDQIIQANPALEAFGNAKTVRND 240
AGKTVNTKRVIQYFA+IA G++ K++ + +GTLEDQII ANP LEAFGNAKTVRND
Sbjct: 183 AGKTVNTKRVIQYFATIAVTGEKKKEEITSGKIQGTLEDQIISANPLLEAFGNAKTVRND 242
Query: 241 NSSRFGKFIRIHFGATGKLASADIETYLLEKSRVIFQLKAERNYHIFYQILSNKKPELLD 300
NSSRFGKFIRIHFG TGKLASADIETYLLEKSRV+FQLKAER+YHIFYQI SNKKPEL++
Sbjct: 243 NSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVVFQLKAERSYHIFYQITSNKKPELIE 302
Query: 301 MLLVTNNPYDYAFVSQGEVSVASIDDSEELMATDSAFDVLGFTSEEKAGVYKLTGAIMHY 360
MLL+T NPYDY FVSQGE+SVASIDD EELMATDSA D+LGFT+EEK +YKLTGA+MHY
Sbjct: 303 MLLITTNPYDYPFVSQGEISVASIDDQEELMATDSAIDILGFTNEEKVSIYKLTGAVMHY 362
Query: 361 GNMKFKQKQREEQAEPDGTEDADKSAYLMGLNSADLLKGLCHPRVKVGNEYVTKGQSVQQ 420
GN+KFKQKQREEQAEPDGTE ADK+AYL LNSADLLK LC+PRVKVGNEYVTKGQ+V+Q
Sbjct: 363 GNLKFKQKQREEQAEPDGTEVADKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTVEQ 422
Query: 421 VYYSIGALAKAVYEKMFNWMVTRINATLETKQPRQYFIGVLDIAGFEIFDFNSFEQLCIN 480
V ++GALAKAVYEKMF WMV RIN L+TKQPRQYFIGVLDIAGFEIFDFNS EQLCIN
Sbjct: 423 VSNAVGALAKAVYEKMFLWMVARINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCIN 482
Query: 481 FTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLQACIDLIEKPMGIMSILEEECM 540
FTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDL ACI+LIEKPMGI SILEEECM
Sbjct: 483 FTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEECM 542
Query: 541 FPKATDMTFKAKLYDNHLGKSNNFQKPRNIKGKQEAHFSLIHYAGTVDYNILGWLEKNKD 600
FPKATD +FK KLYD HLGKS NFQKP+ +KGK EAHF+LIHYAG VDYNI GWLEKNKD
Sbjct: 543 FPKATDTSFKNKLYDQHLGKSANFQKPKVVKGKAEAHFALIHYAGVVDYNITGWLEKNKD 602
Query: 601 PLNETVVALYQKSSLKLMATLFSSYATADT--GDSGKSKGGKKKGSSFQTVSALHRENLN 658
PLNETVV LYQKS++K +A LFS TA+ G KGGKKKGSSFQTVSAL RENLN
Sbjct: 603 PLNETVVGLYQKSAMKTLAQLFSGAQTAEGEGAGGGAKKGGKKKGSSFQTVSALFRENLN 662
Query: 659 KLMTNLRTTHPHFVRCIIPNERKAPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYG 718
KLMTNLR+THPHFVRCIIPNE K PG M++ LV+HQLRCNGVLEGIRICRKGFP+RILY
Sbjct: 663 KLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYA 722
Query: 719 DFRQRYRILNPVAIPEGQFIDSRKGTEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEM 778
DF+QRY++LN AIPEGQFIDS+K +EKLL+S+DIDH QYKFGHTKVFFKAGLLGLLEEM
Sbjct: 723 DFKQRYKVLNASAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEM 782
Query: 779 RDERLSRIITRMQAQARGQLMRIEFKKIVERRDALLVIQWNIRAFMGVKNWPWMKLYFKI 838
RD++L+++ITR QA+ RG L R+E++++VERR+A+ IQ+NIR+FM VK+WPWMKL+FKI
Sbjct: 783 RDDKLAQLITRTQARCRGFLARVEYQRMVERREAIFCIQYNIRSFMNVKHWPWMKLFFKI 842
Query: 839 KPLLKSAETEKEMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQD 898
KPLLKSAETEKEMATMKEEF +IK+ L KSEA+RKELEEKMV+LL+EKNDLQLQVQAE +
Sbjct: 843 KPLLKSAETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAE 902
Query: 899 NLNDAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDIDD 958
L DAEERCDQLIK KIQLEAK+KE+ ER EDEEE+NAELTAKKRKLEDECSELKKDIDD
Sbjct: 903 GLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDD 962
Query: 959 LELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQVEEDK 1018
LELTLAKVEKEKHATENKVKNLTEEMAGLDE IAKLTKEKKALQEAHQQ LDDLQ EEDK
Sbjct: 963 LELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDK 1022
Query: 1019 VNSLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQL 1078
VN+L+K+K+KLEQQVDDLEGSLEQEKK+RMDLERAKRKLEGDLKL QESIMD+EN+K QL
Sbjct: 1023 VNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQL 1082
Query: 1079 EEKLKKKEFDINQQNSKIEDEQVLALQLQKKLKENQARIEELEEELEAERTARAKVEKLR 1138
+EKLKKKEF+I+ SKIEDEQ L +QLQKK+KE QARIEELEEE+EAER +RAK EK R
Sbjct: 1083 DEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQR 1142
Query: 1139 SDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKH 1198
SDLSRELEEISERLEEAGGATS QIEMNKKREAEFQKMRRDLEEATLQHEATAA LRKKH
Sbjct: 1143 SDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKH 1202
Query: 1199 ADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQA 1258
ADSVAELGEQIDNLQRVKQKLEKEKSE K+E+DD+ SN+E + KAK NLEK+ RTLEDQ
Sbjct: 1203 ADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQL 1262
Query: 1259 NEYRVKLEEAQRSLNDFTTQRAKLQTENGELARQLEEKEALISQLTRGKLSYTQQMEDLK 1318
+E + K EE QR +ND T QR +LQTE+GE +RQL+EKEAL+SQL+RGK ++TQQ+E+LK
Sbjct: 1263 SELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELK 1322
Query: 1319 RQLEEEGKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYE 1378
RQLEEE KAKNALAHALQS+RHDCDLLREQYEEE E+KAELQR LSKAN+EVAQWRTKYE
Sbjct: 1323 RQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYE 1382
Query: 1379 TDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSN 1438
TDAIQRTEELEEAKKKLAQRLQ AEE VEAVNAKC+SLEKTK RLQNE+EDLM+DVER+N
Sbjct: 1383 TDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTN 1442
Query: 1439 AAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLE 1498
AA AALDKKQRNFDKILAEWKQK EE+ +ELE+SQKEARSL TELFK+KNAYEESL+ LE
Sbjct: 1443 AACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLE 1502
Query: 1499 TFKRENKNLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQSALEEAEASLEHEEG 1558
T KRENKNLQ+EISDLTEQ+ EGGK +HELEK++KQ+E EK ELQ+ALEEAEASLEHEEG
Sbjct: 1503 TLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEG 1562
Query: 1559 KILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKK 1618
KILR QLE NQ+K+E++RK+AEKDEE++Q KRNH R+V+S+Q++LDAE RSRN+ +R+KK
Sbjct: 1563 KILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKK 1622
Query: 1619 KMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVER 1678
KMEGDLNEMEIQL+HANRMAAEA + ++ Q +LKDTQI LDDA+R+ +DLKE +A+VER
Sbjct: 1623 KMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVER 1682
Query: 1679 RNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMESDLTQ 1738
R NLLQAE+EELRA +EQTERSRK+AEQEL++ SERVQLLH+QNTSLIN KKK+E+D++Q
Sbjct: 1683 RANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQ 1742
Query: 1739 LQSEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHR 1798
+Q E+E+ +QE RNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQT+KDLQ R
Sbjct: 1743 MQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLR 1802
Query: 1799 LDEAEQIALKGGKKQLQKLEARVRELEGELEAEQKRNAESVKGMRKSERRIKELTYQTEE 1858
LDEAEQ+ALKGGKKQ+QKLEARVRELEGE+E+EQKRNAE+VKG+RK ERR+KELTYQTEE
Sbjct: 1803 LDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEE 1862
Query: 1859 DKKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQ 1918
D+KN+LRLQDLVDKLQ KVK+YKRQAEEAEEQ+NTNL+KFRK+QHEL+EAEERADIAESQ
Sbjct: 1863 DRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAESQ 1922
Query: 1919 VNKLRAKSRDIGAK 1932
VNKLR KSR++ K
Sbjct: 1923 VNKLRVKSREVHTK 1936
Score = 187 bits (475), Expect = 9e-47
Identities = 197/868 (22%), Positives = 377/868 (43%), Gaps = 121/868 (13%)
Query: 833 KLYFKIKPLLKSAETEKEMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQ---EKNDL 889
K F+I L E E+ + ++ +IKE + E +E+E + S + +++DL
Sbjct: 1088 KKEFEISNLQSKIEDEQALGIQLQK--KIKELQARIEELEEEIEAERASRAKAEKQRSDL 1145
Query: 890 QLQVQAEQDNLNDAEERCDQLIKNKIQLEAKVKEMNERLED----EEEMNAELTAK---- 941
+++ + L +A I+ + EA+ ++M LE+ E A L K
Sbjct: 1146 SRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADS 1205
Query: 942 --------------KRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGL 987
K+KLE E SE+K +IDDL + V K K E + L ++++ L
Sbjct: 1206 VAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSEL 1265
Query: 988 -------DEIIAKLTKEKKALQEAHQQALDDLQVEEDKVNSLSKSKVKLEQQVDDLEGSL 1040
+I LT ++ LQ + L +E V+ LS+ K QQ+++L+ L
Sbjct: 1266 KSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQL 1325
Query: 1041 EQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQ 1100
E+E K + L A + D L +E + + K +L+ L K ++ Q +K E +
Sbjct: 1326 EEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDA 1385
Query: 1101 VLALQ-LQKKLKENQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGAT 1159
+ + L++ K+ R++ EE +EA A +EK + L E+E++ +E A
Sbjct: 1386 IQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAAC 1445
Query: 1160 SVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAEL-------GEQIDNL 1212
+ K++ F K+ + ++ + A A +K+ EL E +D L
Sbjct: 1446 AAL----DKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQL 1501
Query: 1213 QRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRSL 1272
+ +K +E + E+ D+T + + K LEK+ + +E + E + LEEA+ SL
Sbjct: 1502 ETLK----RENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASL 1557
Query: 1273 NDFTTQRAKLQTE----NGELARQLEEKEALISQLTRGKLSYTQQMED------------ 1316
+ ++Q E E+ R++ EK+ I QL R + + M+
Sbjct: 1558 EHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDA 1617
Query: 1317 --LKRQLEEE--------GKAKNALAHALQSARHDCDLLREQY-------EEETEAKAEL 1359
LK+++E + A A AL++ R+ +L++ + + K +L
Sbjct: 1618 IRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQL 1677
Query: 1360 QRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLA-QRLQDAEEAVEAVNAKCSSLEK 1418
V +AN A E + ++ T E E +K+A Q L DA E V+ ++ + +SL
Sbjct: 1678 AMVERRANLLQA------EIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLIN 1731
Query: 1419 TKHRL-------QNEIEDLMVDVERSNAAA---------------------AALDKKQRN 1450
TK +L Q E+ED++ + + A A L++ ++N
Sbjct: 1732 TKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKN 1791
Query: 1451 FDKILAEWKQKYEES-QSELESSQKEARSLSTELFKLKNAYE-ESLEHLETFKRENKNLQ 1508
++ + + + + +E+ Q L+ +K+ + L + +L+ E E + E K K+ +
Sbjct: 1792 MEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKH-E 1850
Query: 1509 EEISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFN 1568
+ +LT Q E KN+ L+ + +L+ + + EEAE K + Q E
Sbjct: 1851 RRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELE 1910
Query: 1569 QIKAEIERKLAEKDEEMEQAKRNHQRVV 1596
+ + + ++ ++ +++ H +V+
Sbjct: 1911 EAEERADIAESQVNKLRVKSREVHTKVI 1938
Score = 65.1 bits (157), Expect = 6e-10
Identities = 62/313 (19%), Positives = 137/313 (43%), Gaps = 44/313 (14%)
Query: 1638 AAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELE-ELRAVVEQ 1696
+AE +K++ +++ + + +L + +L+E + + + N LQ +++ E + +
Sbjct: 848 SAETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADA 907
Query: 1697 TERSRKLA------EQELIETSERVQLLHSQNTSLINQKKKMESDLTQLQSEVEEAVQEC 1750
ER +L E ++ E +ER + N L +K+K+E + ++L+ ++++
Sbjct: 908 EERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTL 967
Query: 1751 RNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNME----QTIKDLQHRLDEAEQIA 1806
E++ + EE+ +T A L + KK ++ QT+ DLQ D+ +
Sbjct: 968 AKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLT 1027
Query: 1807 LKGGKKQLQKLEARVRELEGELEAEQKRNAESVKGMRKSERRIKELTYQTEEDKKNLLRL 1866
K KLE +V +LEG L E++KK + L
Sbjct: 1028 -----KAKIKLEQQVDDLEGSL----------------------------EQEKKLRMDL 1054
Query: 1867 QDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKS 1926
+ KL+ +K + + E + K +K + E+ + + + ++ +L+ K
Sbjct: 1055 ERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKI 1114
Query: 1927 RDIGAKQKMHDEE 1939
+++ A+ + +EE
Sbjct: 1115 KELQARIEELEEE 1127
Score = 33.9 bits (76), Expect = 1.6
Identities = 24/99 (24%), Positives = 46/99 (46%), Gaps = 4/99 (4%)
Query: 838 IKPLLKSAETEKEMATMKEE----FGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQV 893
+K L K KE+ EE R+++ ++K +A+ K + + ++ N +
Sbjct: 1843 VKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKF 1902
Query: 894 QAEQDNLNDAEERCDQLIKNKIQLEAKVKEMNERLEDEE 932
+ Q L +AEER D +L K +E++ ++ EE
Sbjct: 1903 RKLQHELEEAEERADIAESQVNKLRVKSREVHTKVISEE 1941
>gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo
sapiens]
Length = 1939
Score = 3107 bits (8055), Expect = 0.0
Identities = 1555/1932 (80%), Positives = 1752/1932 (90%), Gaps = 1/1932 (0%)
Query: 2 TDAQMADFGAAAQYLRKSEKERLEAQTRPFDIRTECFVPDDKEEFVKAKILSREGGKVIA 61
+D++MA FG AA +LRKSEKER+EAQ +PFD +T FV D KE +VKA + SREGGKV A
Sbjct: 3 SDSEMAIFGEAAPFLRKSEKERIEAQNKPFDAKTSVFVVDPKESYVKAIVQSREGGKVTA 62
Query: 62 ETENGKTVTVKEDQVLQQNPPKFDKIEDMAMLTFLHEPAVLFNLKERYAAWMIYTYSGLF 121
+TE G TVTVKEDQV NPPK+DKIEDMAM+T LHEPAVL+NLKERYAAWMIYTYSGLF
Sbjct: 63 KTEAGATVTVKEDQVFSMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLF 122
Query: 122 CVTVNPYKWLPVYNAEVVAAYRGKKRSEAPPHIFSISDNAYQYMLTDRENQSILITGESG 181
CVTVNPYKWLPVYN EVV AYRGKKR EAPPHIFSISDNAYQ+MLTDRENQSILITGESG
Sbjct: 123 CVTVNPYKWLPVYNPEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESG 182
Query: 182 AGKTVNTKRVIQYFASIAAIGDRGKKDNANAN-KGTLEDQIIQANPALEAFGNAKTVRND 240
AGKTVNTKRVIQYFA+IA G++ K++ A+ +GTLEDQII ANP LEAFGNAKTVRND
Sbjct: 183 AGKTVNTKRVIQYFATIAVTGEKKKEEPASGKMQGTLEDQIISANPLLEAFGNAKTVRND 242
Query: 241 NSSRFGKFIRIHFGATGKLASADIETYLLEKSRVIFQLKAERNYHIFYQILSNKKPELLD 300
NSSRFGKFIRIHFGATGKLASADIETYLLEKSRV FQLKAER+YHIFYQILSNKKPEL++
Sbjct: 243 NSSRFGKFIRIHFGATGKLASADIETYLLEKSRVTFQLKAERSYHIFYQILSNKKPELIE 302
Query: 301 MLLVTNNPYDYAFVSQGEVSVASIDDSEELMATDSAFDVLGFTSEEKAGVYKLTGAIMHY 360
MLL+T NPYD+AFVSQGE++V SIDD EELMATDSA D+LGFT++EK +YKLTGA+MHY
Sbjct: 303 MLLITTNPYDFAFVSQGEITVPSIDDQEELMATDSAVDILGFTADEKVAIYKLTGAVMHY 362
Query: 361 GNMKFKQKQREEQAEPDGTEDADKSAYLMGLNSADLLKGLCHPRVKVGNEYVTKGQSVQQ 420
GNMKFKQKQREEQAEPDGTE ADK+AYL LNSADLLK LC+PRVKVGNE+VTKGQ+VQQ
Sbjct: 363 GNMKFKQKQREEQAEPDGTEVADKAAYLTSLNSADLLKSLCYPRVKVGNEFVTKGQTVQQ 422
Query: 421 VYYSIGALAKAVYEKMFNWMVTRINATLETKQPRQYFIGVLDIAGFEIFDFNSFEQLCIN 480
VY ++GALAKA+YEKMF WMVTRIN L+TKQPRQYFIGVLDIAGFEIFDFNS EQLCIN
Sbjct: 423 VYNAVGALAKAIYEKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCIN 482
Query: 481 FTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLQACIDLIEKPMGIMSILEEECM 540
FTNEKLQQFFNHHMFVLEQEEYKKEGIEW FIDFGMDL ACI+LIEKPMGI SILEEECM
Sbjct: 483 FTNEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLAACIELIEKPMGIFSILEEECM 542
Query: 541 FPKATDMTFKAKLYDNHLGKSNNFQKPRNIKGKQEAHFSLIHYAGTVDYNILGWLEKNKD 600
FPKATD +FK KLY+ HLGKSNNFQKP+ KGK EAHFSL+HYAGTVDYNI GWL+KNKD
Sbjct: 543 FPKATDTSFKNKLYEQHLGKSNNFQKPKPAKGKPEAHFSLVHYAGTVDYNIAGWLDKNKD 602
Query: 601 PLNETVVALYQKSSLKLMATLFSSYATADTGDSGKSKGGKKKGSSFQTVSALHRENLNKL 660
PLNETVV LYQKS++K +A LFS TA+ G KGGKKKGSSFQTVSAL RENLNKL
Sbjct: 603 PLNETVVGLYQKSAMKTLAFLFSGAQTAEAEGGGGKKGGKKKGSSFQTVSALFRENLNKL 662
Query: 661 MTNLRTTHPHFVRCIIPNERKAPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDF 720
MTNLR+THPHFVRCIIPNE K PG M++ LV+HQLRCNGVLEGIRICRKGFP+RILY DF
Sbjct: 663 MTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADF 722
Query: 721 RQRYRILNPVAIPEGQFIDSRKGTEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRD 780
+QRY++LN AIPEGQFIDS+K +EKLL S++IDH QYKFGHTKVFFKAGLLG LEEMRD
Sbjct: 723 KQRYKVLNASAIPEGQFIDSKKASEKLLGSIEIDHTQYKFGHTKVFFKAGLLGTLEEMRD 782
Query: 781 ERLSRIITRMQAQARGQLMRIEFKKIVERRDALLVIQWNIRAFMGVKNWPWMKLYFKIKP 840
E+L+++ITR QA RG LMR+EF+K++ERR+++ IQ+NIRAFM VK+WPWMKLYFKIKP
Sbjct: 783 EKLAQLITRTQAICRGFLMRVEFRKMMERRESIFCIQYNIRAFMNVKHWPWMKLYFKIKP 842
Query: 841 LLKSAETEKEMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNL 900
LLKSAETEKEMA MKEEF + KE L K+EA+RKELEEKMV+L+QEKNDLQLQVQAE D L
Sbjct: 843 LLKSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADAL 902
Query: 901 NDAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLE 960
DAEERCDQLIK KIQLEAK+KE+ ER EDEEE+NAELTAKKRKLEDECSELKKDIDDLE
Sbjct: 903 ADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLE 962
Query: 961 LTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQVEEDKVN 1020
LTLAKVEKEKHATENKVKNLTEEMAGLDE IAKLTKEKKALQEAHQQ LDDLQ+EEDKVN
Sbjct: 963 LTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQMEEDKVN 1022
Query: 1021 SLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEE 1080
+L+K+K KLEQQVDDLEGSLEQEKK+ MDLERAKRKLEGDLKL QES MD ENDK QL E
Sbjct: 1023 TLTKAKTKLEQQVDDLEGSLEQEKKLCMDLERAKRKLEGDLKLAQESTMDTENDKQQLNE 1082
Query: 1081 KLKKKEFDINQQNSKIEDEQVLALQLQKKLKENQARIEELEEELEAERTARAKVEKLRSD 1140
KLKKKEF+++ KIEDEQ LA+QLQKK+KE QARIEELEEE+EAER +RAK EK RSD
Sbjct: 1083 KLKKKEFEMSNLQGKIEDEQALAIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSD 1142
Query: 1141 LSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHAD 1200
LSRELEEISERLEEAGGATS QIEMNKKREAEFQKMRRDLEE+TLQHEATAAALRKKHAD
Sbjct: 1143 LSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEESTLQHEATAAALRKKHAD 1202
Query: 1201 SVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANE 1260
SVAELGEQID+LQRVKQKLEKEKSE K+E++D+ SNME + KAKAN EK+ RTLEDQ +E
Sbjct: 1203 SVAELGEQIDSLQRVKQKLEKEKSELKMEINDLASNMETVSKAKANFEKMCRTLEDQLSE 1262
Query: 1261 YRVKLEEAQRSLNDFTTQRAKLQTENGELARQLEEKEALISQLTRGKLSYTQQMEDLKRQ 1320
+ K EE QR +N+ + Q+A+L TE+GE +RQL+EK+A++SQL+RGK ++TQQ+E+LKRQ
Sbjct: 1263 IKTKEEEQQRLINELSAQKARLHTESGEFSRQLDEKDAMVSQLSRGKQAFTQQIEELKRQ 1322
Query: 1321 LEEEGKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETD 1380
LEEE KAK+ LAHALQSARHDCDLLREQYEEE EAKAELQR +SKANSEVAQWRTKYETD
Sbjct: 1323 LEEETKAKSTLAHALQSARHDCDLLREQYEEEQEAKAELQRGMSKANSEVAQWRTKYETD 1382
Query: 1381 AIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAA 1440
AIQRTEELEEAKKKLAQRLQDAEE VEAVN+KC+SLEKTK RLQNE+EDLM+DVERSNAA
Sbjct: 1383 AIQRTEELEEAKKKLAQRLQDAEEHVEAVNSKCASLEKTKQRLQNEVEDLMIDVERSNAA 1442
Query: 1441 AAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETF 1500
ALDKKQRNFDK+LAEWKQKYEE+Q+ELE+SQKE+RSLSTELFK+KNAYEESL+HLET
Sbjct: 1443 CIALDKKQRNFDKVLAEWKQKYEETQAELEASQKESRSLSTELFKVKNAYEESLDHLETL 1502
Query: 1501 KRENKNLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQSALEEAEASLEHEEGKI 1560
KRENKNLQ+EISDLTEQ+ EGGK++HELEKV+KQL+ EK ELQ++LEEAEASLEHEEGKI
Sbjct: 1503 KRENKNLQQEISDLTEQIAEGGKHIHELEKVKKQLDHEKSELQTSLEEAEASLEHEEGKI 1562
Query: 1561 LRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKM 1620
LR QLE NQ+K+EI+RK+AEKDEE++Q KRNH RVV+S+Q++LDAE RSRN+ LR+KKKM
Sbjct: 1563 LRIQLELNQVKSEIDRKIAEKDEELDQLKRNHLRVVESMQSTLDAEIRSRNDALRIKKKM 1622
Query: 1621 EGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRN 1680
EGDLNEMEIQL+HANR AAEA + +++ Q +LKDTQ+ LDDA+R DDLKE +A+VERR
Sbjct: 1623 EGDLNEMEIQLNHANRQAAEALRNLRNTQGILKDTQLHLDDAIRGQDDLKEQLAMVERRA 1682
Query: 1681 NLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMESDLTQLQ 1740
NL+QAE+EELRA +E+TER RK+AEQEL++ SERVQLLH+QNTSLIN KKK+E+D++Q+Q
Sbjct: 1683 NLMQAEVEELRASLERTERGRKMAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQ 1742
Query: 1741 SEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLD 1800
E+E+ VQE RNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQT+KDLQ RLD
Sbjct: 1743 GEMEDIVQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLD 1802
Query: 1801 EAEQIALKGGKKQLQKLEARVRELEGELEAEQKRNAESVKGMRKSERRIKELTYQTEEDK 1860
EAEQ+ALKGGKKQ+QKLEARVRELE E+E+EQK N E+VKG+RK ERR+KELTYQTEED+
Sbjct: 1803 EAEQLALKGGKKQIQKLEARVRELESEVESEQKHNVEAVKGLRKHERRVKELTYQTEEDR 1862
Query: 1861 KNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVN 1920
KN+LRLQDLVDKLQ KVKAYKRQAEEAEEQ+N NL+KFRK+QHEL+EA+ERADIAESQVN
Sbjct: 1863 KNILRLQDLVDKLQTKVKAYKRQAEEAEEQSNVNLAKFRKLQHELEEAKERADIAESQVN 1922
Query: 1921 KLRAKSRDIGAK 1932
KLR KSR++ K
Sbjct: 1923 KLRVKSREVHTK 1934
Score = 209 bits (533), Expect = 2e-53
Identities = 208/938 (22%), Positives = 425/938 (45%), Gaps = 87/938 (9%)
Query: 1027 VKLEQQVDDLEGSLEQEKKV---RMDLERAKRKL---EGDLKLTQESIMDLENDKLQLEE 1080
+KL ++ L S E EK++ + + E+ K +L E K +E ++ L +K L+
Sbjct: 834 MKLYFKIKPLLKSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQL 893
Query: 1081 KLKKKEFDINQQNSKIEDEQVLALQLQKKLKENQARIEELEEELEAERTARA-KVEKLRS 1139
+++ + + + + +QL+ K+KE R E+ EEE+ AE TA+ K+E S
Sbjct: 894 QVQAEADALADAEERCDQLIKTKIQLEAKIKEVTERAED-EEEINAELTAKKRKLEDECS 952
Query: 1140 DLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHA 1199
+L ++++++ L + + K++ A K++ EE E A ++K A
Sbjct: 953 ELKKDIDDLELTLAK----------VEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKA 1002
Query: 1200 DSVAELGEQIDNLQRVKQK---LEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLED 1256
A + +D+LQ + K L K K++ + ++DD+ ++EQ K +LE+ R LE
Sbjct: 1003 LQEAHQ-QTLDDLQMEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLCMDLERAKRKLEG 1061
Query: 1257 Q---ANEYRVKLEEAQRSLNDFTTQRAKLQTENGELARQLEEKEALISQLTRGKLSYTQQ 1313
A E + E ++ LN+ + K + E L ++E+++AL QL + +
Sbjct: 1062 DLKLAQESTMDTENDKQQLNE---KLKKKEFEMSNLQGKIEDEQALAIQLQKKIKELQAR 1118
Query: 1314 MEDLKRQLEEEGKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQW 1373
+E+L+ ++E E ++ + + + E+ EE A + + K +E +
Sbjct: 1119 IEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKM 1178
Query: 1374 RTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVD 1433
R E +Q +KK A + + E ++++ LEK K L+ EI DL +
Sbjct: 1179 RRDLEESTLQHEATAAALRKKHADSVAELGEQIDSLQRVKQKLEKEKSELKMEINDLASN 1238
Query: 1434 VERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEES 1493
+E + A A +K R + L+E K K EE Q + + L TE + +E
Sbjct: 1239 METVSKAKANFEKMCRTLEDQLSEIKTKEEEQQRLINELSAQKARLHTESGEFSRQLDEK 1298
Query: 1494 LEHLETFKRENKNLQEEISDLTEQLGEGGKN----VHELEKVRKQLEVEKLELQSALEEA 1549
+ R + ++I +L QL E K H L+ R ++ + + + EE
Sbjct: 1299 DAMVSQLSRGKQAFTQQIEELKRQLEEETKAKSTLAHALQSARHDCDLLREQYE---EEQ 1355
Query: 1550 EASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHQRVVDSLQTSLDAETRS 1609
EA E + G + +A E Q + + E ++ EE+E+AK+ + + + ++A
Sbjct: 1356 EAKAELQRG-MSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNSK 1414
Query: 1610 RNEVLRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLL-------KDTQIQLDDA 1662
+ + K++++ ++ ++ I + +N K+ ++ +L ++TQ +L+ +
Sbjct: 1415 CASLEKTKQRLQNEVEDLMIDVERSNAACIALDKKQRNFDKVLAEWKQKYEETQAELEAS 1474
Query: 1663 VRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQN 1722
+ + L + V+ N + L+ L E +R K +QE+ + +E++
Sbjct: 1475 QKESRSLSTELFKVK---NAYEESLDHL----ETLKRENKNLQQEISDLTEQIAEGGKHI 1527
Query: 1723 TSLINQKKKMESDLTQLQSEVEEAVQECRNAEEKAKKAITDAAMMAEEL-KKEQDTSAHL 1781
L KK+++ + ++LQ+ +EEA + E K + + + E+ +K + L
Sbjct: 1528 HELEKVKKQLDHEKSELQTSLEEAEASLEHEEGKILRIQLELNQVKSEIDRKIAEKDEEL 1587
Query: 1782 ERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELEGELEAEQKRNAESVKG 1841
+++K+N + ++ +Q LD AE + + +K+E + E+E +L ++ AE+++
Sbjct: 1588 DQLKRNHLRVVESMQSTLD-AEIRSRNDALRIKKKMEGDLNEMEIQLNHANRQAAEALRN 1646
Query: 1842 MRKSERRIKELTYQTEEDKKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKV 1901
+R ++ +K+ L L D + R ++ +EQ
Sbjct: 1647 LRNTQGILKDTQ----------LHLDDAI-----------RGQDDLKEQ----------- 1674
Query: 1902 QHELDEAEERADIAESQVNKLRAKSRDIGAKQKMHDEE 1939
L E RA++ +++V +LRA +KM ++E
Sbjct: 1675 ---LAMVERRANLMQAEVEELRASLERTERGRKMAEQE 1709
Score = 191 bits (484), Expect = 8e-48
Identities = 193/870 (22%), Positives = 390/870 (44%), Gaps = 125/870 (14%)
Query: 833 KLYFKIKPLLKSAETEKEMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQ---EKNDL 889
K F++ L E E+ +A ++ +IKE + E +E+E + S + +++DL
Sbjct: 1086 KKEFEMSNLQGKIEDEQALAIQLQK--KIKELQARIEELEEEIEAERASRAKAEKQRSDL 1143
Query: 890 QLQVQAEQDNLNDAEERCDQLIKNKIQLEAKVKEMNERLEDEE-EMNAELTAKKRKLEDE 948
+++ + L +A I+ + EA+ ++M LE+ + A A ++K D
Sbjct: 1144 SRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEESTLQHEATAAALRKKHADS 1203
Query: 949 CSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTK----------EK 998
+EL + ID L+ K+EKEK + ++ +L M + + A K E
Sbjct: 1204 VAELGEQIDSLQRVKQKLEKEKSELKMEINDLASNMETVSKAKANFEKMCRTLEDQLSEI 1263
Query: 999 KALQEAHQQALDDLQVEEDK------------------VNSLSKSKVKLEQQVDDLEGSL 1040
K +E Q+ +++L ++ + V+ LS+ K QQ+++L+ L
Sbjct: 1264 KTKEEEQQRLINELSAQKARLHTESGEFSRQLDEKDAMVSQLSRGKQAFTQQIEELKRQL 1323
Query: 1041 EQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQ 1100
E+E K + L A + D L +E + + K +L+ + K ++ Q +K E +
Sbjct: 1324 EEETKAKSTLAHALQSARHDCDLLREQYEEEQEAKAELQRGMSKANSEVAQWRTKYETDA 1383
Query: 1101 VLALQ-LQKKLKENQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGAT 1159
+ + L++ K+ R+++ EE +EA + A +EK + L E+E++ +E + A
Sbjct: 1384 IQRTEELEEAKKKLAQRLQDAEEHVEAVNSKCASLEKTKQRLQNEVEDLMIDVERSNAAC 1443
Query: 1160 SVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAEL-------GEQIDNL 1212
I ++KK+ F K+ + ++ + +A A +K+ EL E +D+L
Sbjct: 1444 ---IALDKKQR-NFDKVLAEWKQKYEETQAELEASQKESRSLSTELFKVKNAYEESLDHL 1499
Query: 1213 QRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRSL 1272
+ +K +E + E+ D+T + + K LEKV + L+ + +E + LEEA+ SL
Sbjct: 1500 ETLK----RENKNLQQEISDLTEQIAEGGKHIHELEKVKKQLDHEKSELQTSLEEAEASL 1555
Query: 1273 NDFTTQRAKLQTE----NGELARQLEEKEALISQLTRGKLSYTQQMED------------ 1316
+ ++Q E E+ R++ EK+ + QL R L + M+
Sbjct: 1556 EHEEGKILRIQLELNQVKSEIDRKIAEKDEELDQLKRNHLRVVESMQSTLDAEIRSRNDA 1615
Query: 1317 --LKRQLEEE--------GKAKNALAHALQSARHDCDLLREQY-------EEETEAKAEL 1359
+K+++E + A A AL++ R+ +L++ + + K +L
Sbjct: 1616 LRIKKKMEGDLNEMEIQLNHANRQAAEALRNLRNTQGILKDTQLHLDDAIRGQDDLKEQL 1675
Query: 1360 QRVLSKAN---SEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSL 1416
V +AN +EV + R +++RTE +K Q L DA E V+ ++ + +SL
Sbjct: 1676 AMVERRANLMQAEVEELRA-----SLERTER---GRKMAEQELLDASERVQLLHTQNTSL 1727
Query: 1417 EKTKHRL-------QNEIEDLMVDVERSNAAA---------------------AALDKKQ 1448
TK +L Q E+ED++ + + A A L++ +
Sbjct: 1728 INTKKKLETDISQIQGEMEDIVQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMK 1787
Query: 1449 RNFDKILAEWKQKYEES-QSELESSQKEARSLSTELFKLKNAYEESLEH-LETFKRENKN 1506
+N ++ + + + + +E+ Q L+ +K+ + L + +L++ E +H +E K K+
Sbjct: 1788 KNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELESEVESEQKHNVEAVKGLRKH 1847
Query: 1507 LQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLE 1566
+ + +LT Q E KN+ L+ + +L+ + + EEAE K + Q E
Sbjct: 1848 -ERRVKELTYQTEEDRKNILRLQDLVDKLQTKVKAYKRQAEEAEEQSNVNLAKFRKLQHE 1906
Query: 1567 FNQIKAEIERKLAEKDEEMEQAKRNHQRVV 1596
+ K + ++ ++ +++ H +V+
Sbjct: 1907 LEEAKERADIAESQVNKLRVKSREVHTKVI 1936
>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo
sapiens]
Length = 1937
Score = 3104 bits (8047), Expect = 0.0
Identities = 1554/1931 (80%), Positives = 1752/1931 (90%), Gaps = 2/1931 (0%)
Query: 2 TDAQMADFGAAAQYLRKSEKERLEAQTRPFDIRTECFVPDDKEEFVKAKILSREGGKVIA 61
+DA+MA FG AA YLRKSEKER+EAQ +PFD +T FV + KE +VK+ I S+EGGKV
Sbjct: 5 SDAEMAVFGEAAPYLRKSEKERIEAQNKPFDAKTSVFVAEPKESYVKSTIQSKEGGKVTV 64
Query: 62 ETENGKTVTVKEDQVLQQNPPKFDKIEDMAMLTFLHEPAVLFNLKERYAAWMIYTYSGLF 121
+TE G T+TV+EDQV NPPK+DKIEDMAM+T LHEP VL+NLKERYAAWMIYTYSGLF
Sbjct: 65 KTEGGATLTVREDQVFPMNPPKYDKIEDMAMMTHLHEPGVLYNLKERYAAWMIYTYSGLF 124
Query: 122 CVTVNPYKWLPVYNAEVVAAYRGKKRSEAPPHIFSISDNAYQYMLTDRENQSILITGESG 181
CVTVNPYKWLPVY EVVAAYRGKKR EAPPHIFSISDNAYQ+MLTDRENQSILITGESG
Sbjct: 125 CVTVNPYKWLPVYKPEVVAAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESG 184
Query: 182 AGKTVNTKRVIQYFASIAAIGDRGKKDNANANKGTLEDQIIQANPALEAFGNAKTVRNDN 241
AGKTVNTKRVIQYFA+IA G++ KKD + +GTLEDQII ANP LEAFGNAKTVRNDN
Sbjct: 185 AGKTVNTKRVIQYFATIAVTGEK-KKDESGKMQGTLEDQIISANPLLEAFGNAKTVRNDN 243
Query: 242 SSRFGKFIRIHFGATGKLASADIETYLLEKSRVIFQLKAERNYHIFYQILSNKKPELLDM 301
SSRFGKFIRIHFG TGKLASADIETYLLEKSRV FQLKAER+YHIFYQI SNKKP+L++M
Sbjct: 244 SSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQITSNKKPDLIEM 303
Query: 302 LLVTNNPYDYAFVSQGEVSVASIDDSEELMATDSAFDVLGFTSEEKAGVYKLTGAIMHYG 361
LL+T NPYDYAFVSQGE++V SIDD EELMATDSA D+LGFT EEK +YKLTGA+MHYG
Sbjct: 304 LLITTNPYDYAFVSQGEITVPSIDDQEELMATDSAIDILGFTPEEKVSIYKLTGAVMHYG 363
Query: 362 NMKFKQKQREEQAEPDGTEDADKSAYLMGLNSADLLKGLCHPRVKVGNEYVTKGQSVQQV 421
NMKFKQKQREEQAEPDGTE ADK+AYL LNSADLLK LC+PRVKVGNEYVTKGQ+VQQV
Sbjct: 364 NMKFKQKQREEQAEPDGTEVADKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTVQQV 423
Query: 422 YYSIGALAKAVYEKMFNWMVTRINATLETKQPRQYFIGVLDIAGFEIFDFNSFEQLCINF 481
Y ++GALAKAVYEKMF WMVTRIN L+TKQPRQYFIGVLDIAGFEIFDFNS EQLCINF
Sbjct: 424 YNAVGALAKAVYEKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINF 483
Query: 482 TNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLQACIDLIEKPMGIMSILEEECMF 541
TNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDL ACI+LIEKP+GI SILEEECMF
Sbjct: 484 TNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPLGIFSILEEECMF 543
Query: 542 PKATDMTFKAKLYDNHLGKSNNFQKPRNIKGKQEAHFSLIHYAGTVDYNILGWLEKNKDP 601
PKATD +FK KLYD HLGKS NFQKP+ +KGK EAHFSLIHYAGTVDYNI GWL+KNKDP
Sbjct: 544 PKATDTSFKNKLYDQHLGKSANFQKPKVVKGKAEAHFSLIHYAGTVDYNITGWLDKNKDP 603
Query: 602 LNETVVALYQKSSLKLMATLFSSYATADTGDSGKSKGGKKKGSSFQTVSALHRENLNKLM 661
LN+TVV LYQKS++K +A+LFS+YA+A+ DS KG KKKGSSFQTVSAL RENLNKLM
Sbjct: 604 LNDTVVGLYQKSAMKTLASLFSTYASAEA-DSSAKKGAKKKGSSFQTVSALFRENLNKLM 662
Query: 662 TNLRTTHPHFVRCIIPNERKAPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFR 721
TNLR+THPHFVRCIIPNE K PG M++ LV+HQLRCNGVLEGIRICRKGFP+RILYGDF+
Sbjct: 663 TNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYGDFK 722
Query: 722 QRYRILNPVAIPEGQFIDSRKGTEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDE 781
QRY++LN AIPEGQFIDS+K +EKLL+S+DIDH QYKFGHTKVFFKAGLLGLLEEMRDE
Sbjct: 723 QRYKVLNASAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDE 782
Query: 782 RLSRIITRMQAQARGQLMRIEFKKIVERRDALLVIQWNIRAFMGVKNWPWMKLYFKIKPL 841
+L++IITR QA RG LMR+E++K+++RR+AL IQ+N+RAFM VK+WPWMKL+FKIKPL
Sbjct: 783 KLAQIITRTQAVCRGFLMRVEYQKMLQRREALFCIQYNVRAFMNVKHWPWMKLFFKIKPL 842
Query: 842 LKSAETEKEMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLN 901
LKSAETEKEMATMKEEF + K+ L KSEA+RKELEEKMV+LL+EKNDLQLQVQ+E D+L
Sbjct: 843 LKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLA 902
Query: 902 DAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLEL 961
DAEERC+QLIKNKIQLEAK+KE+ ER E+EEE+NAELTAKKRKLEDECSELKKDIDDLEL
Sbjct: 903 DAEERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLEL 962
Query: 962 TLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQVEEDKVNS 1021
TLAKVEKEKHATENKVKNLTEEMAGLDE IAKL+KEKKALQE HQQ LDDLQ EEDKVN
Sbjct: 963 TLAKVEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDKVNI 1022
Query: 1022 LSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEEK 1081
L+K+K KLEQQVDDLEGSLEQEKK+RMDLERAKRKLEGDLKL QES MD+ENDK QL+EK
Sbjct: 1023 LTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQLDEK 1082
Query: 1082 LKKKEFDINQQNSKIEDEQVLALQLQKKLKENQARIEELEEELEAERTARAKVEKLRSDL 1141
L+KKEF+I+ SKIEDEQ + +QLQKK+KE QARIEEL EE+EAER +RAK EK RSDL
Sbjct: 1083 LEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQRSDL 1142
Query: 1142 SRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADS 1201
SRELEEISERLEEAGGATS Q+E+NKKREAEFQK+RRDLEEATLQHEA AALRKKHADS
Sbjct: 1143 SRELEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRKKHADS 1202
Query: 1202 VAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANEY 1261
+AELGEQIDNLQRVKQKLEKEKSE K+E DD++SN E I KAK NLEK+ R+LEDQ +E
Sbjct: 1203 MAELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGNLEKMCRSLEDQVSEL 1262
Query: 1262 RVKLEEAQRSLNDFTTQRAKLQTENGELARQLEEKEALISQLTRGKLSYTQQMEDLKRQL 1321
+ K EE QR +ND T QRA+LQTE GE +RQL+EK+AL+SQL+R K + TQQ+E+LK QL
Sbjct: 1263 KTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKHQL 1322
Query: 1322 EEEGKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDA 1381
EEE KAKNALAHALQS+RHDCDLLREQYEEE E KAELQR LSKANSEVAQWRTKYETDA
Sbjct: 1323 EEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDA 1382
Query: 1382 IQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAA 1441
IQRTEELEEAKKKLAQRLQ+AEE VEAVNAKC+SLEKTK RLQNE+EDLM+DVERSNAA
Sbjct: 1383 IQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAAC 1442
Query: 1442 AALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFK 1501
AALDKKQRNFDK+L+EWKQKYEE+Q+ELE+SQKE+RSLSTELFK+KN YEESL+ LET +
Sbjct: 1443 AALDKKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELFKVKNVYEESLDQLETLR 1502
Query: 1502 RENKNLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQSALEEAEASLEHEEGKIL 1561
RENKNLQ+EISDLTEQ+ EGGK +HELEK++KQ+E EK E+Q+ALEEAEASLEHEEGKIL
Sbjct: 1503 RENKNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKIL 1562
Query: 1562 RAQLEFNQIKAEIERKLAEKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKME 1621
R QLE NQ+K+E++RK+AEKDEE++Q KRNH RVV+++Q++LDAE RSRN+ LRVKKKME
Sbjct: 1563 RIQLELNQVKSEVDRKIAEKDEEIDQLKRNHTRVVETMQSTLDAEIRSRNDALRVKKKME 1622
Query: 1622 GDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNN 1681
GDLNEMEIQL+HANR+AAE+ + ++ Q +LK+TQ+ LDDA+R +DLKE +AIVERR N
Sbjct: 1623 GDLNEMEIQLNHANRLAAESLRNYRNTQGILKETQLHLDDALRGQEDLKEQLAIVERRAN 1682
Query: 1682 LLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMESDLTQLQS 1741
LLQAE+EEL A +EQTERSRK+AEQEL++ SERVQLLH+QNTSLIN KKK+E+D++QLQS
Sbjct: 1683 LLQAEIEELWATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQLQS 1742
Query: 1742 EVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDE 1801
EVEE +QE RNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKN+EQT+KDLQHRLDE
Sbjct: 1743 EVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDE 1802
Query: 1802 AEQIALKGGKKQLQKLEARVRELEGELEAEQKRNAESVKGMRKSERRIKELTYQTEEDKK 1861
AEQ+ALKGGKKQ+QKLEARVRELEGE+E EQKRNAE+VKG+RK ERR+KELTYQTEED+K
Sbjct: 1803 AEQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHERRVKELTYQTEEDRK 1862
Query: 1862 NLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNK 1921
N+LRLQDLVDKLQ KVK+YKRQAEEAEEQ+N NLSKFRK+QHEL+EAEERADIAESQVNK
Sbjct: 1863 NVLRLQDLVDKLQAKVKSYKRQAEEAEEQSNANLSKFRKLQHELEEAEERADIAESQVNK 1922
Query: 1922 LRAKSRDIGAK 1932
LR KSR++ K
Sbjct: 1923 LRVKSREVHTK 1933
Score = 189 bits (479), Expect = 3e-47
Identities = 196/874 (22%), Positives = 385/874 (44%), Gaps = 121/874 (13%)
Query: 833 KLYFKIKPLLKSAETEKEMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQ---EKNDL 889
K F+I L+ E E+ + ++ +IKE + E +E+E + S + +++DL
Sbjct: 1085 KKEFEISNLISKIEDEQAVEIQLQK--KIKELQARIEELGEEIEAERASRAKAEKQRSDL 1142
Query: 890 QLQVQAEQDNLNDAEERCDQLIKNKIQLEAKVKEMNERLED----EEEMNAELTAK---- 941
+++ + L +A ++ + EA+ +++ LE+ E M A L K
Sbjct: 1143 SRELEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRKKHADS 1202
Query: 942 --------------KRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGL 987
K+KLE E SELK + DDL + K K E ++L ++++ L
Sbjct: 1203 MAELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGNLEKMCRSLEDQVSEL 1262
Query: 988 -------DEIIAKLTKEKKALQEAHQQALDDLQVEEDKVNSLSKSKVKLEQQVDDLEGSL 1040
+I LT ++ LQ + L ++ V+ LS+SK QQ+++L+ L
Sbjct: 1263 KTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKHQL 1322
Query: 1041 EQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQ 1100
E+E K + L A + D L +E + + K +L+ L K ++ Q +K E +
Sbjct: 1323 EEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDA 1382
Query: 1101 VLALQ-LQKKLKENQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGAT 1159
+ + L++ K+ R++E EE +EA A +EK + L E+E++ +E + A
Sbjct: 1383 IQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAAC 1442
Query: 1160 SVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKL 1219
+ + + + + ++ EE + EA+ R + ++L ++ + L
Sbjct: 1443 AALDKKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELFKVKNVYEESLDQL-ETL 1501
Query: 1220 EKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQR 1279
+E + E+ D+T + + K LEK+ + +E + E + LEEA+ SL +
Sbjct: 1502 RRENKNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKI 1561
Query: 1280 AKLQTE----NGELARQLEEKEALISQLTRGKLSYTQQMEDLKRQLEEEGKAKN------ 1329
++Q E E+ R++ EK+ I QL R ++T+ +E ++ L+ E +++N
Sbjct: 1562 LRIQLELNQVKSEVDRKIAEKDEEIDQLKR---NHTRVVETMQSTLDAEIRSRNDALRVK 1618
Query: 1330 -------------------ALAHALQSARHDCDLLREQY-------EEETEAKAELQRVL 1363
A +L++ R+ +L+E + + K +L V
Sbjct: 1619 KKMEGDLNEMEIQLNHANRLAAESLRNYRNTQGILKETQLHLDDALRGQEDLKEQLAIVE 1678
Query: 1364 SKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRL 1423
+AN A+ + T E+ E ++K Q L DA E V+ ++ + +SL TK +L
Sbjct: 1679 RRANLLQAEIEELWAT-----LEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKL 1733
Query: 1424 QNEIEDLMVDVE----------------------------RSNAAAAALDKKQRNFDKIL 1455
+N++ L +VE + +A L++ ++N ++ +
Sbjct: 1734 ENDVSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTV 1793
Query: 1456 AEWKQKYEES-QSELESSQKEARSLSTELFKLKNAYE-ESLEHLETFKRENKNLQEEISD 1513
+ + + +E+ Q L+ +K+ + L + +L+ E E + E K K+ + + +
Sbjct: 1794 KDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKH-ERRVKE 1852
Query: 1514 LTEQLGEGGKNVHELEKVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAE 1573
LT Q E KNV L+ + +L+ + + EEAE K F +++ E
Sbjct: 1853 LTYQTEEDRKNVLRLQDLVDKLQAKVKSYKRQAEEAEEQSNANLSK-------FRKLQHE 1905
Query: 1574 IERKLAEKDEEMEQAKRNHQRVVD-SLQTSLDAE 1606
+E AE+ ++ +++ N RV + T + AE
Sbjct: 1906 LEE--AEERADIAESQVNKLRVKSREVHTKISAE 1937
Score = 36.2 bits (82), Expect = 0.32
Identities = 38/169 (22%), Positives = 68/169 (40%), Gaps = 26/169 (15%)
Query: 1771 LKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELEGELEA 1830
L K +T + MK+ ++T K +L K EA+ +ELE ++
Sbjct: 842 LLKSAETEKEMATMKEEFQKT-------------------KDELAKSEAKRKELEEKMVT 882
Query: 1831 EQKRNAESVKGMRKSERRIKELTYQTEEDKKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQ 1890
K + ++ + + + E+ KN ++L+ K+K +AEE EE
Sbjct: 883 LLKEKNDLQLQVQSEADSLADAEERCEQLIKNKIQLE-------AKIKEVTERAEEEEEI 935
Query: 1891 ANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSRDIGAKQKMHDEE 1939
+K RK++ E E ++ D E + K+ + K K EE
Sbjct: 936 NAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEE 984
>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
sapiens]
Length = 1940
Score = 3054 bits (7917), Expect = 0.0
Identities = 1530/1939 (78%), Positives = 1745/1939 (89%), Gaps = 3/1939 (0%)
Query: 2 TDAQMADFGAAAQYLRKSEKERLEAQTRPFDIRTECFVPDDKEEFVKAKILSREGGKVIA 61
+D +M FG AA +LRKSEKER+EAQ +PFD +T CFV D KEE+ K KI S + GKV
Sbjct: 3 SDTEMEVFGIAAPFLRKSEKERIEAQNQPFDAKTYCFVVDSKEEYAKGKIKSSQDGKVTV 62
Query: 62 ETENGKTVTVKEDQVLQQNPPKFDKIEDMAMLTFLHEPAVLFNLKERYAAWMIYTYSGLF 121
ETE+ +T+ VK + V NPPKFD+IEDMAMLT L+EPAVL+NLK+RY +WMIYTYSGLF
Sbjct: 63 ETEDNRTLVVKPEDVYAMNPPKFDRIEDMAMLTHLNEPAVLYNLKDRYTSWMIYTYSGLF 122
Query: 122 CVTVNPYKWLPVYNAEVVAAYRGKKRSEAPPHIFSISDNAYQYMLTDRENQSILITGESG 181
CVTVNPYKWLPVYN EVV YRGKKR EAPPHIFSISDNAYQ+MLTDRENQSILITGESG
Sbjct: 123 CVTVNPYKWLPVYNPEVVEGYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESG 182
Query: 182 AGKTVNTKRVIQYFASIAAIGDRGKKDNANANKGTLEDQIIQANPALEAFGNAKTVRNDN 241
AGKTVNTKRVIQYFA+IAA GD KK ++ KGTLEDQII ANP LEAFGNAKTVRNDN
Sbjct: 183 AGKTVNTKRVIQYFATIAATGDLAKKKDSKM-KGTLEDQIISANPLLEAFGNAKTVRNDN 241
Query: 242 SSRFGKFIRIHFGATGKLASADIETYLLEKSRVIFQLKAERNYHIFYQILSNKKPELLDM 301
SSRFGKFIRIHFG TGKLASADIETYLLEKSRV FQLKAER+YHIFYQILSNKKPEL+++
Sbjct: 242 SSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQILSNKKPELIEL 301
Query: 302 LLVTNNPYDYAFVSQGEVSVASIDDSEELMATDSAFDVLGFTSEEKAGVYKLTGAIMHYG 361
LL+T NPYDY F+SQGE+ VASIDD+EEL+ATDSA D+LGFT EEK+G+YKLTGA+MHYG
Sbjct: 302 LLITTNPYDYPFISQGEILVASIDDAEELLATDSAIDILGFTPEEKSGLYKLTGAVMHYG 361
Query: 362 NMKFKQKQREEQAEPDGTEDADKSAYLMGLNSADLLKGLCHPRVKVGNEYVTKGQSVQQV 421
NMKFKQKQREEQAEPDGTE ADK+AYLMGLNS+DLLK LC PRVKVGNEYVTKGQ+V QV
Sbjct: 362 NMKFKQKQREEQAEPDGTEVADKTAYLMGLNSSDLLKALCFPRVKVGNEYVTKGQTVDQV 421
Query: 422 YYSIGALAKAVYEKMFNWMVTRINATLETKQPRQYFIGVLDIAGFEIFDFNSFEQLCINF 481
++++ AL+K+VYEK+F WMVTRIN L+TK PRQ+FIGVLDIAGFEIF++NS EQLCINF
Sbjct: 422 HHAVNALSKSVYEKLFLWMVTRINQQLDTKLPRQHFIGVLDIAGFEIFEYNSLEQLCINF 481
Query: 482 TNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLQACIDLIEKPMGIMSILEEECMF 541
TNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDL ACI+LIEKPMGI SILEEECMF
Sbjct: 482 TNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEECMF 541
Query: 542 PKATDMTFKAKLYDNHLGKSNNFQKPRNIKGKQEAHFSLIHYAGTVDYNILGWLEKNKDP 601
PKATD +FK KLYD HLGKSNNFQKP+ +KG+ EAHFSLIHYAGTVDY++ GWLEKNKDP
Sbjct: 542 PKATDTSFKNKLYDQHLGKSNNFQKPKVVKGRAEAHFSLIHYAGTVDYSVSGWLEKNKDP 601
Query: 602 LNETVVALYQKSSLKLMATLFSSYATADTGDSGKSKGGKKKGSSFQTVSALHRENLNKLM 661
LNETVV LYQKSS +L+A L++++ATAD DSGK K KKKGSSFQTVSAL RENLNKLM
Sbjct: 602 LNETVVGLYQKSSNRLLAHLYATFATADA-DSGKKKVAKKKGSSFQTVSALFRENLNKLM 660
Query: 662 TNLRTTHPHFVRCIIPNERKAPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFR 721
+NLRTTHPHFVRCIIPNE K PG M++ LV+HQLRCNGVLEGIRICRKGFPNRILYGDF+
Sbjct: 661 SNLRTTHPHFVRCIIPNETKTPGAMEHSLVLHQLRCNGVLEGIRICRKGFPNRILYGDFK 720
Query: 722 QRYRILNPVAIPEGQFIDSRKGTEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDE 781
QRYR+LN AIPEGQFIDS+K EKLL+S+DIDH QYKFGHTKVFFKAGLLG LEEMRD+
Sbjct: 721 QRYRVLNASAIPEGQFIDSKKACEKLLASIDIDHTQYKFGHTKVFFKAGLLGTLEEMRDD 780
Query: 782 RLSRIITRMQAQARGQLMRIEFKKIVERRDALLVIQWNIRAFMGVKNWPWMKLYFKIKPL 841
RL+++ITR QA RG LMR+EF+K+V+RR+++ IQ+NIR+FM VK+WPWMKL+FKIKPL
Sbjct: 781 RLAKLITRTQAVCRGFLMRVEFQKMVQRRESIFCIQYNIRSFMNVKHWPWMKLFFKIKPL 840
Query: 842 LKSAETEKEMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLN 901
LKSAETEKEMATMKEEF + K+ L KSEA+RKELEEK+V+L+QEKNDLQLQVQAE +NL
Sbjct: 841 LKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLL 900
Query: 902 DAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLEL 961
DAEERCDQLIK K QLEAK+KE+ ER EDEEE+NAELTAKKRKLEDECSELKKDIDDLEL
Sbjct: 901 DAEERCDQLIKAKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLEL 960
Query: 962 TLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQVEEDKVNS 1021
TLAKVEKEKHATENKVKNLTEE++GLDE IAKLT+EKKALQEAHQQALDDLQ EEDKVNS
Sbjct: 961 TLAKVEKEKHATENKVKNLTEELSGLDETIAKLTREKKALQEAHQQALDDLQAEEDKVNS 1020
Query: 1022 LSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEEK 1081
L+K+K KLEQQV+DLE SLEQEKK+R+DLER KRKLEGDLKL QESI+DLENDK QL+E+
Sbjct: 1021 LNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDER 1080
Query: 1082 LKKKEFDINQQNSKIEDEQVLALQLQKKLKENQARIEELEEELEAERTARAKVEKLRSDL 1141
LKKK+F+ Q SK+EDEQ L LQ QKK+KE QARIEELEEE+EAER RAK EK RSD
Sbjct: 1081 LKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDY 1140
Query: 1142 SRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADS 1201
+RELEE+SERLEEAGG TS QIE+NKKREAEF K+RRDLEEATLQHEA AALRKKHADS
Sbjct: 1141 ARELEELSERLEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEAMVAALRKKHADS 1200
Query: 1202 VAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANEY 1261
VAELGEQIDNLQRVKQKLEKEKSEFKLE+DD++S+ME + K+KANLEK+ RTLEDQ +E
Sbjct: 1201 VAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEA 1260
Query: 1262 RVKLEEAQRSLNDFTTQRAKLQTENGELARQLEEKEALISQLTRGKLSYTQQMEDLKRQL 1321
R K EE QRSL++ TTQ+++LQTE GEL+RQLEEKE+++SQL+R K ++TQQ E+LKRQL
Sbjct: 1261 RGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQL 1320
Query: 1322 EEEGKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDA 1381
EEE KAKNALAHALQS+RHDCDLLREQYEEE E KAELQR LSKANSEVAQWRTKYETDA
Sbjct: 1321 EEENKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDA 1380
Query: 1382 IQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAA 1441
IQRTEELEEAKKKLAQRLQD+EE VEAVNAKC+SLEKTK RLQ E+EDLMVDVER+N+ A
Sbjct: 1381 IQRTEELEEAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANSLA 1440
Query: 1442 AALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFK 1501
AALDKKQRNFDK+LAEWK K EESQ+ELE+S KE+RSLSTELFKLKNAYEE+L+ LET K
Sbjct: 1441 AALDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQLETVK 1500
Query: 1502 RENKNLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQSALEEAEASLEHEEGKIL 1561
RENKNL++EI+DLTEQ+ E GK +HELEK RKQ+E+EK ++Q ALEEAEA+LEHEE KIL
Sbjct: 1501 RENKNLEQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQLALEEAEAALEHEEAKIL 1560
Query: 1562 RAQLEFNQIKAEIERKLAEKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKME 1621
R QLE Q+K+EI+RK+AEKDEE+EQ KRN+QR V+++Q++LDAE RSRNE +R+KKKME
Sbjct: 1561 RIQLELTQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSALDAEVRSRNEAIRLKKKME 1620
Query: 1622 GDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNN 1681
GDLNE+EIQLSHANR AAE K ++S+Q LKDTQ+ LDDA+R +DLKE +AIVERR N
Sbjct: 1621 GDLNEIEIQLSHANRQAAETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRAN 1680
Query: 1682 LLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMESDLTQLQS 1741
LLQAE+EELRA +EQTER+RKLAEQEL++++ERVQLLH+QNTSLI+ KKK+E+DL QLQS
Sbjct: 1681 LLQAEVEELRATLEQTERARKLAEQELLDSNERVQLLHTQNTSLIHTKKKLETDLMQLQS 1740
Query: 1742 EVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDE 1801
EVE+A ++ RNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKN+EQT+KDLQHRLDE
Sbjct: 1741 EVEDASRDARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDE 1800
Query: 1802 AEQIALKGGKKQLQKLEARVRELEGELEAEQKRNAESVKGMRKSERRIKELTYQTEEDKK 1861
AEQ+ALKGGKKQ+QKLE R+RELE ELE EQK+N ESVKG+RK ERR+KELTYQ+EED+K
Sbjct: 1801 AEQLALKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLRKYERRVKELTYQSEEDRK 1860
Query: 1862 NLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNK 1921
N+LRLQDLVDKLQ+KVK+YKRQAEEA+EQAN +L+KFRK QHEL+EAEERADIAESQVNK
Sbjct: 1861 NVLRLQDLVDKLQVKVKSYKRQAEEADEQANAHLTKFRKAQHELEEAEERADIAESQVNK 1920
Query: 1922 LRAKSRDI-GAKQKMHDEE 1939
LRAK+RD ++ +H+ E
Sbjct: 1921 LRAKTRDFTSSRMVVHESE 1939
>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
sapiens]
Length = 1938
Score = 2992 bits (7757), Expect = 0.0
Identities = 1501/1937 (77%), Positives = 1715/1937 (88%), Gaps = 2/1937 (0%)
Query: 2 TDAQMADFGAAAQYLRKSEKERLEAQTRPFDIRTECFVPDDKEEFVKAKILSREGGKVIA 61
+DA+MA FG AA YLRK EKER+EAQ RPFD + CFV D+KE +VK I +RE KVI
Sbjct: 3 SDAEMAIFGEAAPYLRKPEKERIEAQNRPFDSKKACFVADNKEMYVKGMIQTRENDKVIV 62
Query: 62 ETENGKTVTVKEDQVLQQNPPKFDKIEDMAMLTFLHEPAVLFNLKERYAAWMIYTYSGLF 121
+T + + +T+ DQV NPPKFDKIEDMAM+T LHEPAVL+NLKERYAAWMIYTYSGLF
Sbjct: 63 KTLDDRMLTLNNDQVFPMNPPKFDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLF 122
Query: 122 CVTVNPYKWLPVYNAEVVAAYRGKKRSEAPPHIFSISDNAYQYMLTDRENQSILITGESG 181
CVTVNPYKWLPVY EVVAAYRGKKR EAPPHIFSISDNAYQ+MLTDR+NQSILITGESG
Sbjct: 123 CVTVNPYKWLPVYKPEVVAAYRGKKRQEAPPHIFSISDNAYQFMLTDRDNQSILITGESG 182
Query: 182 AGKTVNTKRVIQYFASIAAIGDRGKKDNANANKGTLEDQIIQANPALEAFGNAKTVRNDN 241
AGKTVNTKRVIQYFA+IA GD+ K+ +GTLEDQIIQANP LEAFGNAKTVRNDN
Sbjct: 183 AGKTVNTKRVIQYFATIAVTGDKKKETQPGKMQGTLEDQIIQANPLLEAFGNAKTVRNDN 242
Query: 242 SSRFGKFIRIHFGATGKLASADIETYLLEKSRVIFQLKAERNYHIFYQILSNKKPELLDM 301
SSRFGKFIRIHFGATGKLASADIETYLLEKSRV FQL +ER+YHIFYQI+SNKKPEL+D+
Sbjct: 243 SSRFGKFIRIHFGATGKLASADIETYLLEKSRVTFQLSSERSYHIFYQIMSNKKPELIDL 302
Query: 302 LLVTNNPYDYAFVSQGEVSVASIDDSEELMATDSAFDVLGFTSEEKAGVYKLTGAIMHYG 361
LL++ NP+D+ FVSQGEV+VASIDDSEEL+ATD+A D+LGF+SEEK G+YKLTGA+MHYG
Sbjct: 303 LLISTNPFDFPFVSQGEVTVASIDDSEELLATDNAIDILGFSSEEKVGIYKLTGAVMHYG 362
Query: 362 NMKFKQKQREEQAEPDGTEDADKSAYLMGLNSADLLKGLCHPRVKVGNEYVTKGQSVQQV 421
NMKFKQKQREEQAEPDGTE ADK+ YLMGLNSA++LKGLC PRVKVGNEYVTKGQ+VQQV
Sbjct: 363 NMKFKQKQREEQAEPDGTEVADKAGYLMGLNSAEMLKGLCCPRVKVGNEYVTKGQNVQQV 422
Query: 422 YYSIGALAKAVYEKMFNWMVTRINATLETKQPRQYFIGVLDIAGFEIFDFNSFEQLCINF 481
S+GALAKAVYEKMF WMVTRIN L+TKQPRQYFIGVLDIAGFEIFDFNS EQLCINF
Sbjct: 423 TNSVGALAKAVYEKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINF 482
Query: 482 TNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLQACIDLIEKPMGIMSILEEECMF 541
TNEKLQQFFNHHMFVLEQEEYKKEGIEW FIDFGMDL ACI+LIEKPMGI SILEEECMF
Sbjct: 483 TNEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLAACIELIEKPMGIFSILEEECMF 542
Query: 542 PKATDMTFKAKLYDNHLGKSNNFQKPRNIKGKQEAHFSLIHYAGTVDYNILGWLEKNKDP 601
PKATD +FK KLYD HLGKSNNFQKP+ KGK EAHFSL+HYAGTVDYNI GWL+KNKDP
Sbjct: 543 PKATDTSFKNKLYDQHLGKSNNFQKPKPAKGKAEAHFSLVHYAGTVDYNIAGWLDKNKDP 602
Query: 602 LNETVVALYQKSSLKLMATLFSSYATADTGDSGKSK-GGKKKGSSFQTVSALHRENLNKL 660
LNETVV LYQKSSLKL++ LFS+YA A+TGDSG SK GGKKKGSSFQTVSA+ RENLNKL
Sbjct: 603 LNETVVGLYQKSSLKLLSFLFSNYAGAETGDSGGSKKGGKKKGSSFQTVSAVFRENLNKL 662
Query: 661 MTNLRTTHPHFVRCIIPNERKAPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDF 720
MTNLR+THPHFVRC+IPNE K PGVMD+ LVMHQLRCNGVLEGIRICRKGFP+RILY DF
Sbjct: 663 MTNLRSTHPHFVRCLIPNETKTPGVMDHYLVMHQLRCNGVLEGIRICRKGFPSRILYADF 722
Query: 721 RQRYRILNPVAIPEGQFIDSRKGTEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRD 780
+QRYRILN AIPEGQFIDS+ +EKLL+S+D+D Q++FG+TKVFFKAGLLGLLEEMRD
Sbjct: 723 KQRYRILNASAIPEGQFIDSKNASEKLLNSIDVDREQFRFGNTKVFFKAGLLGLLEEMRD 782
Query: 781 ERLSRIITRMQAQARGQLMRIEFKKIVERRDALLVIQWNIRAFMGVKNWPWMKLYFKIKP 840
E+L ++T QA RG LMR+EFKK++ERRD++ IQ+NIR+FM VK+WPWM L+FKIKP
Sbjct: 783 EKLVTLMTSTQAVCRGYLMRVEFKKMMERRDSIFCIQYNIRSFMNVKHWPWMNLFFKIKP 842
Query: 841 LLKSAETEKEMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNL 900
LLKSAE EKEMATMKE+F R KE L +SEARRKELEEKMVSLLQEKNDLQLQVQ+E +NL
Sbjct: 843 LLKSAEAEKEMATMKEDFERTKEELARSEARRKELEEKMVSLLQEKNDLQLQVQSETENL 902
Query: 901 NDAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLE 960
DAEERC+ LIK+KI LEAKVKE+ ERLE+EEEMN+EL AKKR LED+CS LK+DIDDLE
Sbjct: 903 MDAEERCEGLIKSKILLEAKVKELTERLEEEEEMNSELVAKKRNLEDKCSSLKRDIDDLE 962
Query: 961 LTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQVEEDKVN 1020
LTL KVEKEKHATENKVKNL+EEM L+E I+KLTKEKK+LQEAHQQ LDDLQVEEDKVN
Sbjct: 963 LTLTKVEKEKHATENKVKNLSEEMTALEENISKLTKEKKSLQEAHQQTLDDLQVEEDKVN 1022
Query: 1021 SLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEE 1080
L K KLEQQ DDLEGSLEQEKK+R DLERAKRKLEGDLK++QESIMDLENDK Q+EE
Sbjct: 1023 GLIKINAKLEQQTDDLEGSLEQEKKLRADLERAKRKLEGDLKMSQESIMDLENDKQQIEE 1082
Query: 1081 KLKKKEFDINQQNSKIEDEQVLALQLQKKLKENQARIEELEEELEAERTARAKVEKLRSD 1140
KLKKKEF+++Q +KI+DEQV +LQ QKK+KE QARIEELEEE+EAE T RAK+EK RSD
Sbjct: 1083 KLKKKEFELSQLQAKIDDEQVHSLQFQKKIKELQARIEELEEEIEAEHTLRAKIEKQRSD 1142
Query: 1141 LSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHAD 1200
L+RELEEISERLEEA GATS QIEMNKKREAEFQKMRRDLEEATLQHEATAA LRKK AD
Sbjct: 1143 LARELEEISERLEEASGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKQAD 1202
Query: 1201 SVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANE 1260
SVAELGEQIDNLQRVKQKLEKEKSE K+E+DD+ SN+E + K+K+N+E+ RT+EDQ +E
Sbjct: 1203 SVAELGEQIDNLQRVKQKLEKEKSELKMEIDDMASNIEALSKSKSNIERTCRTVEDQFSE 1262
Query: 1261 YRVKLEEAQRSLNDFTTQRAKLQTENGELARQLEEKEALISQLTRGKLSYTQQMEDLKRQ 1320
+ K E+ + ++D Q+A+LQT+NGEL+ ++EEKE+LISQLT+ K + TQQ+E+LKRQ
Sbjct: 1263 IKAKDEQQTQLIHDLNMQKARLQTQNGELSHRVEEKESLISQLTKSKQALTQQLEELKRQ 1322
Query: 1321 LEEEGKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETD 1380
+EEE KAKNA+AHALQS+RHDCDLLREQYEEE EAKAELQR LSKANSEVAQWRTKYETD
Sbjct: 1323 MEEETKAKNAMAHALQSSRHDCDLLREQYEEEQEAKAELQRALSKANSEVAQWRTKYETD 1382
Query: 1381 AIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAA 1440
AIQRTEELEEAKKKLAQRLQ+AEE E N+KC+SLEKTK RLQ E+EDLM D+ERS+ A
Sbjct: 1383 AIQRTEELEEAKKKLAQRLQEAEENTETANSKCASLEKTKQRLQGEVEDLMRDLERSHTA 1442
Query: 1441 AAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETF 1500
A LDKKQRNFDK+LAEWKQK +ESQ+ELE++QKE+RSLSTELFK++NAYEE ++ LET
Sbjct: 1443 CATLDKKQRNFDKVLAEWKQKLDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQLETL 1502
Query: 1501 KRENKNLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQSALEEAEASLEHEEGKI 1560
+RENKNLQEEISDLTEQ+ E GKN+ E EK +K +E EK +LQ ALEE E SLEHEE KI
Sbjct: 1503 RRENKNLQEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEESKI 1562
Query: 1561 LRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKM 1620
LR QLE +Q+K+E++RK+ EKDEE+EQ KRN QR ++LQ+ LDAE RSRN+ LR+KKKM
Sbjct: 1563 LRVQLELSQVKSELDRKVIEKDEEIEQLKRNSQRAAEALQSVLDAEIRSRNDALRLKKKM 1622
Query: 1621 EGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRN 1680
EGDLNEMEIQL H+NR AE QK ++++Q LKD+Q+ LDDA+R+N+DLKE +AIVERRN
Sbjct: 1623 EGDLNEMEIQLGHSNRQMAETQKHLRTVQGQLKDSQLHLDDALRSNEDLKEQLAIVERRN 1682
Query: 1681 NLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMESDLTQLQ 1740
LL ELEE++ +EQTER+R+L+EQEL++ S+RVQLLHSQNTSLIN KKK+E+D+ Q Q
Sbjct: 1683 GLLLEELEEMKVALEQTERTRRLSEQELLDASDRVQLLHSQNTSLINTKKKLEADIAQCQ 1742
Query: 1741 SEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLD 1800
+EVE ++QE RNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKN+EQT+KDLQHRLD
Sbjct: 1743 AEVENSIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLD 1802
Query: 1801 EAEQIALKGGKKQLQKLEARVRELEGELEAEQKRNAESVKGMRKSERRIKELTYQTEEDK 1860
EAEQ+ALKGGKKQ+QKLE RVRELE EL+ EQKR AE++KG K ER++KE+TYQ EED
Sbjct: 1803 EAEQLALKGGKKQIQKLENRVRELENELDVEQKRGAEALKGAHKYERKVKEMTYQAEEDH 1862
Query: 1861 KNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVN 1920
KN+LRLQDLVDKLQ KVK+YKRQAEEAEEQANT LS+ R+VQHEL+EA ERADIAESQVN
Sbjct: 1863 KNILRLQDLVDKLQAKVKSYKRQAEEAEEQANTQLSRCRRVQHELEEAAERADIAESQVN 1922
Query: 1921 KLRAKSRDIGAKQKMHD 1937
KLRAKSRD+G+ QKM +
Sbjct: 1923 KLRAKSRDVGS-QKMEE 1938
Score = 78.2 bits (191), Expect = 7e-14
Identities = 92/408 (22%), Positives = 181/408 (44%), Gaps = 69/408 (16%)
Query: 1562 RAQLEFNQIKAEIERKLAEKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKME 1621
R Q F K + L EEM K + +L TS A R + KK ME
Sbjct: 757 REQFRFGNTKVFFKAGLLGLLEEMRDEK------LVTLMTSTQAVCRGYLMRVEFKKMME 810
Query: 1622 GDLNEMEIQLSHANRM-------------------AAEAQKQVKSLQSLLKDTQIQLDDA 1662
+ IQ + + M +AEA+K++ +++ + T+ +L +
Sbjct: 811 RRDSIFCIQYNIRSFMNVKHWPWMNLFFKIKPLLKSAEAEKEMATMKEDFERTKEELARS 870
Query: 1663 VRANDDLKEN-IAIVERRNNL---LQAELEELRAVVEQTE---RSRKLAEQELIETSERV 1715
+L+E +++++ +N+L +Q+E E L E+ E +S+ L E ++ E +ER+
Sbjct: 871 EARRKELEEKMVSLLQEKNDLQLQVQSETENLMDAEERCEGLIKSKILLEAKVKELTERL 930
Query: 1716 QLLHSQNTSLINQKKKMESDLTQLQSEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQ 1775
+ N+ L+ +K+ +E + L+ ++++ E++ ++EE+ +
Sbjct: 931 EEEEEMNSELVAKKRNLEDKCSSLKRDIDDLELTLTKVEKEKHATENKVKNLSEEMTALE 990
Query: 1776 DTSAHLERMKKNME----QTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELEGELEAE 1831
+ + L + KK+++ QT+ DLQ E+ + G K KLE + +LEG LE E
Sbjct: 991 ENISKLTKEKKSLQEAHQQTLDDLQ-----VEEDKVNGLIKINAKLEQQTDDLEGSLEQE 1045
Query: 1832 QKRNAESVKGMRKSERRIKELTYQTEEDKKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQA 1891
+K A+ + RK E +K ++ ++ D +N K+Q EE
Sbjct: 1046 KKLRADLERAKRKLEGDLK-MSQESIMDLEN-----------------DKQQIEE----- 1082
Query: 1892 NTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSRDIGAKQKMHDEE 1939
K +K + EL + + + D + + + K +++ A+ + +EE
Sbjct: 1083 -----KLKKKEFELSQLQAKIDDEQVHSLQFQKKIKELQARIEELEEE 1125
>gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta [Homo
sapiens]
Length = 1983
Score = 2655 bits (6881), Expect = 0.0
Identities = 1326/1937 (68%), Positives = 1643/1937 (84%), Gaps = 8/1937 (0%)
Query: 6 MADFGAAAQYLRKSEKERLEAQTRPFDIRTECFVPDDKEEFVKAKILSRE-GGKVIAETE 64
+++ G +A+YLR+ +E + T P+D + +VPD+++ +V+A++ S GG+V ET+
Sbjct: 46 VSELGESARYLRQGYQEMTKVHTIPWDGKKRVWVPDEQDAYVEAEVKSEATGGRVTVETK 105
Query: 65 NGKTVTVKEDQVLQQNPPKFDKIEDMAMLTFLHEPAVLFNLKERYAAWMIYTYSGLFCVT 124
+ K + V+E ++ NPP+FD +EDMAM+T L+E +VL NL++RYA WMIYTYSGLFCVT
Sbjct: 106 DQKVLMVREAELQPMNPPRFDLLEDMAMMTHLNEASVLHNLRQRYARWMIYTYSGLFCVT 165
Query: 125 VNPYKWLPVYNAEVVAAYRGKKRSEAPPHIFSISDNAYQYMLTDRENQSILITGESGAGK 184
+NPYKWLPVY A VVAAY+GK+RS++PPHI++++DNAY ML +R+NQS+LITGESGAGK
Sbjct: 166 INPYKWLPVYTASVVAAYKGKRRSDSPPHIYAVADNAYNDMLRNRDNQSMLITGESGAGK 225
Query: 185 TVNTKRVIQYFASIAAIGDR-GKKDNANANK--GTLEDQIIQANPALEAFGNAKTVRNDN 241
TVNTKRVIQYFA +AA+GD GKK A K GTLEDQII+ANPA+EAFGNAKT+RNDN
Sbjct: 226 TVNTKRVIQYFAIVAALGDGPGKKAQFLATKTGGTLEDQIIEANPAMEAFGNAKTLRNDN 285
Query: 242 SSRFGKFIRIHFGATGKLASADIETYLLEKSRVIFQLKAERNYHIFYQILSNKKPELLDM 301
SSRFGKFIRIHFG +GKLASADI++YLLEKSRVIFQL ER+YH++YQILS +KPEL DM
Sbjct: 286 SSRFGKFIRIHFGPSGKLASADIDSYLLEKSRVIFQLPGERSYHVYYQILSGRKPELQDM 345
Query: 302 LLVTNNPYDYAFVSQGEVSVASIDDSEELMATDSAFDVLGFTSEEKAGVYKLTGAIMHYG 361
LL++ NPYDY F SQG ++V +++D EEL+ATD A D+LGF+ +EK YK+ GA++H+G
Sbjct: 346 LLLSMNPYDYHFCSQGVITVDNMNDGEELIATDHAMDILGFSVDEKCACYKIVGALLHFG 405
Query: 362 NMKFKQKQREEQAEPDGTEDADKSAYLMGLNSADLLKGLCHPRVKVGNEYVTKGQSVQQV 421
NMKFKQKQREEQAE DGTE ADK+AYLMG++S DLLKGL HPRV+VGNEYVTKGQSV+QV
Sbjct: 406 NMKFKQKQREEQAEADGTESADKAAYLMGVSSGDLLKGLLHPRVRVGNEYVTKGQSVEQV 465
Query: 422 YYSIGALAKAVYEKMFNWMVTRINATLETKQPRQYFIGVLDIAGFEIFDFNSFEQLCINF 481
+++GALAKA Y+++F W+V+RIN TL+TK PRQ+FIGVLDIAGFEIF+FNSFEQLCINF
Sbjct: 466 VFAVGALAKATYDRLFRWLVSRINQTLDTKLPRQFFIGVLDIAGFEIFEFNSFEQLCINF 525
Query: 482 TNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLQACIDLIEKPMGIMSILEEECMF 541
TNEKLQQFFN HMFVLEQEEYK+EGI+W FIDFG+DLQ CIDLIEKP+GI+SILEEECMF
Sbjct: 526 TNEKLQQFFNQHMFVLEQEEYKREGIDWVFIDFGLDLQPCIDLIEKPLGILSILEEECMF 585
Query: 542 PKATDMTFKAKLYDNHLGKSNNFQKPR-NIKGKQEAHFSLIHYAGTVDYNILGWLEKNKD 600
PKA+D +F+AKLYDNH GKS NFQ+PR + K K +AHF ++HYAG V Y+I+GWLEKNKD
Sbjct: 586 PKASDASFRAKLYDNHAGKSPNFQQPRPDKKRKYQAHFEVVHYAGVVPYSIVGWLEKNKD 645
Query: 601 PLNETVVALYQKSSLKLMATLFSSYATADTGDSGKS--KGGKKKGSSFQTVSALHRENLN 658
PLNETVV ++QKS +L+ATL+ +YA + + + KS K +KK +SFQTVS LH+ENLN
Sbjct: 646 PLNETVVPIFQKSQNRLLATLYENYAGSCSTEPPKSGVKEKRKKAASFQTVSQLHKENLN 705
Query: 659 KLMTNLRTTHPHFVRCIIPNERKAPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYG 718
KLMTNLR T PHFVRCI+PNE K PGVMD LV+HQLRCNGVLEGIRICR+GFPNR+LY
Sbjct: 706 KLMTNLRATQPHFVRCIVPNENKTPGVMDAFLVLHQLRCNGVLEGIRICRQGFPNRLLYT 765
Query: 719 DFRQRYRILNPVAIPEGQFIDSRKGTEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEM 778
DFRQRYRILNP AIP+ F+DSRK TEKLL SLD+DH QY+FGHTKVFFKAGLLG+LEE+
Sbjct: 766 DFRQRYRILNPSAIPDDTFMDSRKATEKLLGSLDLDHTQYQFGHTKVFFKAGLLGVLEEL 825
Query: 779 RDERLSRIITRMQAQARGQLMRIEFKKIVERRDALLVIQWNIRAFMGVKNWPWMKLYFKI 838
RD+RL++++T +QA++RG+LMR+E+++++ RDAL IQWNIRAF VKNW WMKL+FK+
Sbjct: 826 RDQRLAKVLTLLQARSRGRLMRLEYQRLLGGRDALFTIQWNIRAFNAVKNWSWMKLFFKM 885
Query: 839 KPLLKSAETEKEMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQD 898
KPLL+SA+ E+E+A ++ E ++ L +EA+R+ELEE VS+ QEKNDL LQ+QAEQD
Sbjct: 886 KPLLRSAQAEEELAALRAELRGLRGALAAAEAKRQELEETHVSITQEKNDLALQLQAEQD 945
Query: 899 NLNDAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDIDD 958
NL DAEERC LIK+K+QLE KVKE++ERLEDEEE+NA+L A++RKLEDEC+ELKKDIDD
Sbjct: 946 NLADAEERCHLLIKSKVQLEGKVKELSERLEDEEEVNADLAARRRKLEDECTELKKDIDD 1005
Query: 959 LELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQVEEDK 1018
L+LTLAK EKEK ATENKVKNLTEEMA LDE +A+LTKEKKALQEAHQQAL DLQ EED+
Sbjct: 1006 LKLTLAKAEKEKQATENKVKNLTEEMAALDESVARLTKEKKALQEAHQQALGDLQAEEDR 1065
Query: 1019 VNSLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQL 1078
V++L+K+K++LEQQV+DLE SLEQEKK+RMD ERAKRKLEGDLKLTQES+ D DK QL
Sbjct: 1066 VSALTKAKLRLEQQVEDLECSLEQEKKLRMDTERAKRKLEGDLKLTQESVADAAQDKQQL 1125
Query: 1079 EEKLKKKEFDINQQNSKIEDEQVLALQLQKKLKENQARIEELEEELEAERTARAKVEKLR 1138
EEKLKKK+ +++Q + ++EDEQ+L Q+QKK+KE QAR EELEEELEAER ARA+VEK R
Sbjct: 1126 EEKLKKKDSELSQLSLRVEDEQLLGAQMQKKIKELQARAEELEEELEAERAARARVEKQR 1185
Query: 1139 SDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKH 1198
++ +RELEE+SERLEEAGGA++ Q E +KREAE ++RR+LEEA L+HEAT AALR+K
Sbjct: 1186 AEAARELEELSERLEEAGGASAGQREGCRKREAELGRLRRELEEAALRHEATVAALRRKQ 1245
Query: 1199 ADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQA 1258
A+ AELGEQ+D+LQRV+QKLEKEKSE ++E+DD+ +N+E + +AKA+ EK+ RT EDQ
Sbjct: 1246 AEGAAELGEQVDSLQRVRQKLEKEKSELRMEVDDLAANVETLTRAKASAEKLCRTYEDQL 1305
Query: 1259 NEYRVKLEEAQRSLNDFTTQRAKLQTENGELARQLEEKEALISQLTRGKLSYTQQMEDLK 1318
+E ++K+EE QR L D +TQR +LQTE+GEL+R LEEKE LISQL+RGK Q +E+L+
Sbjct: 1306 SEAKIKVEELQRQLADASTQRGRLQTESGELSRLLEEKECLISQLSRGKALAAQSLEELR 1365
Query: 1319 RQLEEEGKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYE 1378
RQLEEE KAK+ALAHA+Q+ RHDCDLLREQ+EEE EA+AELQR+LSKAN+EVAQWR+KYE
Sbjct: 1366 RQLEEESKAKSALAHAVQALRHDCDLLREQHEEEAEAQAELQRLLSKANAEVAQWRSKYE 1425
Query: 1379 TDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSN 1438
DAIQRTEELEEAKKKLA RLQ+AEE VEA NAKCSSLEK K RLQ E ED+ +++ER+
Sbjct: 1426 ADAIQRTEELEEAKKKLALRLQEAEEGVEAANAKCSSLEKAKLRLQTESEDVTLELERAT 1485
Query: 1439 AAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLE 1498
+AAAALDKKQR+ ++ L E +++ EE Q ELE++Q+E+R L TELF+L++ +EE+LE LE
Sbjct: 1486 SAAAALDKKQRHLERALEERRRQEEEMQRELEAAQRESRGLGTELFRLRHGHEEALEALE 1545
Query: 1499 TFKRENKNLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQSALEEAEASLEHEEG 1558
T KRENKNLQEEISDLT+Q+ GK++ ELEK +K LE EK E+Q+ALEEAE +LE EE
Sbjct: 1546 TLKRENKNLQEEISDLTDQVSLSGKSIQELEKTKKALEGEKSEIQAALEEAEGALELEET 1605
Query: 1559 KILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKK 1618
K LR QLE +Q+KAE++RKLAEKDEE +RNHQR V+SLQ SLDAETR+RNE LR+KK
Sbjct: 1606 KTLRIQLELSQVKAEVDRKLAEKDEECANLRRNHQRAVESLQASLDAETRARNEALRLKK 1665
Query: 1619 KMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVER 1678
KMEGDLN++E+QL HA R A EAQ + +Q+ LK+ Q D+ R +L E +ER
Sbjct: 1666 KMEGDLNDLELQLGHATRQATEAQAATRLMQAQLKEEQAGRDEEQRLAAELHEQAQALER 1725
Query: 1679 RNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMESDLTQ 1738
R +LL AELEELRA +EQ ERSR+LAEQEL+E +ER+ LLHSQNT L+NQKKK+E+DL Q
Sbjct: 1726 RASLLAAELEELRAALEQGERSRRLAEQELLEATERLNLLHSQNTGLLNQKKKLEADLAQ 1785
Query: 1739 LQSEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHR 1798
L EVEEA QE R AEEKAKKAITDAAMMAEELKKEQDTSAHLERMKK +EQT+++LQ R
Sbjct: 1786 LSGEVEEAAQERREAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKTLEQTVRELQAR 1845
Query: 1799 LDEAEQIALKGGKKQLQKLEARVRELEGELEAEQKRNAESVKGMRKSERRIKELTYQTEE 1858
L+EAEQ AL+GGKKQ+QKLEA+VRELE EL+AEQK++AE++KG+RK ERR+KEL YQ EE
Sbjct: 1846 LEEAEQAALRGGKKQVQKLEAKVRELEAELDAEQKKHAEALKGVRKHERRVKELAYQAEE 1905
Query: 1859 DKKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQ 1918
D+KNL R+QDLVDKLQ KVK+YKRQ EEAE+QANTNL+K+RK QHELD+AEERAD+AE+Q
Sbjct: 1906 DRKNLARMQDLVDKLQSKVKSYKRQFEEAEQQANTNLAKYRKAQHELDDAEERADMAETQ 1965
Query: 1919 VNKLRAKSRD-IGAKQK 1934
NKLRA++RD +G K K
Sbjct: 1966 ANKLRARTRDALGPKHK 1982
Score = 75.5 bits (184), Expect = 5e-13
Identities = 67/309 (21%), Positives = 145/309 (46%), Gaps = 36/309 (11%)
Query: 1638 AAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKE-NIAIVERRNNL---LQAELEELRAV 1693
+A+A++++ +L++ L+ + L A +L+E +++I + +N+L LQAE + L
Sbjct: 891 SAQAEEELAALRAELRGLRGALAAAEAKRQELEETHVSITQEKNDLALQLQAEQDNLADA 950
Query: 1694 VEQTE---RSRKLAEQELIETSERVQLLHSQNTSLINQKKKMESDLTQLQSEVEEAVQEC 1750
E+ +S+ E ++ E SER++ N L +++K+E + T+L+ ++++
Sbjct: 951 EERCHLLIKSKVQLEGKVKELSERLEDEEEVNADLAARRRKLEDECTELKKDIDDLKLTL 1010
Query: 1751 RNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGG 1810
AE++ + + EE+ ++ A L + KK L EA Q AL
Sbjct: 1011 AKAEKEKQATENKVKNLTEEMAALDESVARLTKEKK-----------ALQEAHQQAL--- 1056
Query: 1811 KKQLQKLEARVRELEGELEAEQKRNAESVKGMRKSERRIKELTYQTEEDKKNLLRLQDLV 1870
G+L+AE+ R + K + E+++++L E++KK + +
Sbjct: 1057 ---------------GDLQAEEDRVSALTKAKLRLEQQVEDLECSLEQEKKLRMDTERAK 1101
Query: 1871 DKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSRDIG 1930
KL+ +K + +A + K +K EL + R + + +++ K +++
Sbjct: 1102 RKLEGDLKLTQESVADAAQDKQQLEEKLKKKDSELSQLSLRVEDEQLLGAQMQKKIKELQ 1161
Query: 1931 AKQKMHDEE 1939
A+ + +EE
Sbjct: 1162 ARAEELEEE 1170
>gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens]
Length = 1946
Score = 2409 bits (6242), Expect = 0.0
Identities = 1206/1929 (62%), Positives = 1562/1929 (80%), Gaps = 11/1929 (0%)
Query: 6 MADFGAAAQYLRKSEKERLEAQTRPFDIRTECFVPDDKEEFVKAKIL-SREGGKVIAETE 64
++D G AA +LR+SE E L Q D + +C++PD + +++A++ S + G VI ET
Sbjct: 23 LSDLGEAAAFLRRSEAELLLLQATALDGKKKCWIPDGENAYIEAEVKGSEDDGTVIVETA 82
Query: 65 NGKTVTVKEDQVLQQNPPKFDKIEDMAMLTFLHEPAVLFNLKERYAAWMIYTYSGLFCVT 124
+G+++++KED++ Q NPP+F+ IEDMAMLT L+E +VL LK RY WMIYTYSGLFCVT
Sbjct: 83 DGESLSIKEDKIQQMNPPEFEMIEDMAMLTHLNEASVLHTLKRRYGQWMIYTYSGLFCVT 142
Query: 125 VNPYKWLPVYNAEVVAAYRGKKRSEAPPHIFSISDNAYQYMLTDRENQSILITGESGAGK 184
+NPYKWLPVY EV+AAY+GK+RSEAPPHIF++++NA+Q ML +RENQSIL TGESGAGK
Sbjct: 143 INPYKWLPVYQKEVMAAYKGKRRSEAPPHIFAVANNAFQDMLHNRENQSILFTGESGAGK 202
Query: 185 TVNTKRVIQYFASIAAIGDRGKKDNANANKGTLEDQIIQANPALEAFGNAKTVRNDNSSR 244
TVN+K +IQYFA+IAA+ + KK +G LEDQI+QAN LEAFGNAKT+RNDNSSR
Sbjct: 203 TVNSKHIIQYFATIAAMIESRKK------QGALEDQIMQANTILEAFGNAKTLRNDNSSR 256
Query: 245 FGKFIRIHFGATGKLASADIETYLLEKSRVIFQLKAERNYHIFYQILSNKKPELLDMLLV 304
FGKFIR+HFGA G L+S DI+ YLLEKSRVIFQ ERNYHIFYQILS +K EL D+LLV
Sbjct: 257 FGKFIRMHFGARGMLSSVDIDIYLLEKSRVIFQQAGERNYHIFYQILSGQK-ELHDLLLV 315
Query: 305 TNNPYDYAFVSQGEVSVASIDDSEELMATDSAFDVLGFTSEEKAGVYKLTGAIMHYGNMK 364
+ NP D+ F S G V+V S+DD+EEL+AT+ A D+LGF +EK G YKLTGAIMH+GNMK
Sbjct: 316 SANPSDFHFCSCGAVTVESLDDAEELLATEQAMDILGFLPDEKYGCYKLTGAIMHFGNMK 375
Query: 365 FKQKQREEQAEPDGTEDADKSAYLMGLNSADLLKGLCHPRVKVGNEYVTKGQSVQQVYYS 424
FKQK REEQ E DGTE+ADK+A+LMG+NS++L+K L HPR+KVGNEYVT+GQ+++QV +
Sbjct: 376 FKQKPREEQLEADGTENADKAAFLMGINSSELVKCLIHPRIKVGNEYVTRGQTIEQVTCA 435
Query: 425 IGALAKAVYEKMFNWMVTRINATLETKQPRQYFIGVLDIAGFEIFDFNSFEQLCINFTNE 484
+GAL+K++YE+MF W+V RIN L+ K RQ+FIG+LDI GFEI ++NS EQLCINFTNE
Sbjct: 436 VGALSKSMYERMFKWLVARINRALDAKLSRQFFIGILDITGFEILEYNSLEQLCINFTNE 495
Query: 485 KLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLQACIDLIEKPMGIMSILEEECMFPKA 544
KLQQFFN HMFVLEQEEYKKE IEW I FG+DLQACIDLIEKPMGI+SILEEECMFPKA
Sbjct: 496 KLQQFFNWHMFVLEQEEYKKESIEWVSIGFGLDLQACIDLIEKPMGILSILEEECMFPKA 555
Query: 545 TDMTFKAKLYDNHLGKSNNFQKPRNIKGKQEAHFSLIHYAGTVDYNILGWLEKNKDPLNE 604
TD+TFK KL+DNH GKS + QKP+ K K EAHF L+HYAG V YNI GWLEKNKD LNE
Sbjct: 556 TDLTFKTKLFDNHFGKSVHLQKPKPDKKKFEAHFELVHYAGVVPYNISGWLEKNKDLLNE 615
Query: 605 TVVALYQKSSLKLMATLFSSYATADTG-DSGKSKGGKKKGSSFQTVSALHRENLNKLMTN 663
TVVA++QKSS +L+A+LF +Y + D+ G+ K +KKG+SFQTV++LH+ENLNKLMTN
Sbjct: 616 TVVAVFQKSSNRLLASLFENYMSTDSAIPFGEKK--RKKGASFQTVASLHKENLNKLMTN 673
Query: 664 LRTTHPHFVRCIIPNERKAPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQR 723
L++T PHFVRCI PN K PG++D LV+ QLRCNGVLEG RICR+GFPNR+ Y DF+QR
Sbjct: 674 LKSTAPHFVRCINPNVNKIPGILDPYLVLQQLRCNGVLEGTRICREGFPNRLQYADFKQR 733
Query: 724 YRILNPVAIPEGQFIDSRKGTEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERL 783
Y ILNP P+ +F+ SRK E+LL SL+IDH QY+FG TKVFFKAG LG LE +RDERL
Sbjct: 734 YCILNPRTFPKSKFVSSRKAAEELLGSLEIDHTQYRFGITKVFFKAGFLGQLEAIRDERL 793
Query: 784 SRIITRMQAQARGQLMRIEFKKIVERRDALLVIQWNIRAFMGVKNWPWMKLYFKIKPLLK 843
S++ T QA+A+G+LMRI+F+KI+E RDAL++IQWNIRAFM VKNWPWM+L+FKIKPL+K
Sbjct: 794 SKVFTLFQARAQGKLMRIKFQKILEERDALILIQWNIRAFMAVKNWPWMRLFFKIKPLVK 853
Query: 844 SAETEKEMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLNDA 903
S+E +E+A +KEE ++++ LEKSE +R+EL+ K VSL QEKNDL LQ+QAEQ+ L +
Sbjct: 854 SSEVGEEVAGLKEECAQLQKALEKSEFQREELKAKQVSLTQEKNDLILQLQAEQETLANV 913
Query: 904 EERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTL 963
EE+C+ LIK+KIQLEA+VKE++ER+E+EEE+N+ELTA+ RKLEDEC ELKK+IDDLE L
Sbjct: 914 EEQCEWLIKSKIQLEARVKELSERVEEEEEINSELTARGRKLEDECFELKKEIDDLETML 973
Query: 964 AKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQVEEDKVNSLS 1023
K EKEK TE+KVKNLTEE+ L+E I+KL + K +QEAHQQ LDDL +EE+K++SLS
Sbjct: 974 VKSEKEKRTTEHKVKNLTEEVEFLNEDISKLNRAAKVVQEAHQQTLDDLHMEEEKLSSLS 1033
Query: 1024 KSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEEKLK 1083
K+ +KLEQQVD+LEG+LEQE+K RM+ ER KLEG+LKL +ES+ +LE+ + L E+L+
Sbjct: 1034 KANLKLEQQVDELEGALEQERKARMNCERELHKLEGNLKLNRESMENLESSQRHLAEELR 1093
Query: 1084 KKEFDINQQNSKIEDEQVLALQLQKKLKENQARIEELEEELEAERTARAKVEKLRSDLSR 1143
KKE +++Q NSK+E+E+ L QLQK +KE Q +I++L+E+LEAERT RAK+E+ R+DL++
Sbjct: 1094 KKELELSQMNSKVENEKGLVAQLQKTVKELQTQIKDLKEKLEAERTTRAKMERERADLTQ 1153
Query: 1144 ELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVA 1203
+L +++ERLEE GG++ Q+E+ KK+E +FQK+ RD+EEATL E T+A+L+K+HADS+A
Sbjct: 1154 DLADLNERLEEVGGSSLAQLEITKKQETKFQKLHRDMEEATLHFETTSASLKKRHADSLA 1213
Query: 1204 ELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANEYRV 1263
EL Q++NLQ+VKQKLEK+KS+ +LE+DD+ + +EQ+ +AKAN EK+ E++ +E
Sbjct: 1214 ELEGQVENLQQVKQKLEKDKSDLQLEVDDLLTRVEQMTRAKANAEKLCTLYEERLHEATA 1273
Query: 1264 KLEEAQRSLNDFTTQRAKLQTENGELARQLEEKEALISQLTRGKLSYTQQMEDLKRQLEE 1323
KL++ + ND Q+ KL +E+GE R+LEEKEALI+QL+R K ++T+Q+EDL+ QLE+
Sbjct: 1274 KLDKVTQLANDLAAQKTKLWSESGEFLRRLEEKEALINQLSREKSNFTRQIEDLRGQLEK 1333
Query: 1324 EGKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQ 1383
E K+++ALAHALQ A+ DCDLLREQYEEE E KAEL R LSK N+E+ QWR KYE + IQ
Sbjct: 1334 ETKSQSALAHALQKAQRDCDLLREQYEEEQEVKAELHRTLSKVNAEMVQWRMKYENNVIQ 1393
Query: 1384 RTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAA 1443
RTE+LE+AKK+LA RLQ+A EA+ NA+ +SLE+ +H+LQ E+ D + D+ + +AAA
Sbjct: 1394 RTEDLEDAKKELAIRLQEAAEAMGVANARNASLERARHQLQLELGDALSDLGKVRSAAAR 1453
Query: 1444 LDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRE 1503
LD+KQ K LA+WKQK+EESQ+ L++SQKE ++LSTEL KLKN YEES+ ET +RE
Sbjct: 1454 LDQKQLQSGKALADWKQKHEESQALLDASQKEVQALSTELLKLKNTYEESIVGQETLRRE 1513
Query: 1504 NKNLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQSALEEAEASLEHEEGKILRA 1563
NKNLQEEIS+LT Q+ EG KN+ E+EKV+K +E EK E+Q LEE E +LE E KIL
Sbjct: 1514 NKNLQEEISNLTNQVREGTKNLTEMEKVKKLIEEEKTEVQVTLEETEGALERNESKILHF 1573
Query: 1564 QLEFNQIKAEIERKLAEKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGD 1623
QLE + KAE+ERKL+EKDEE+E +R Q +DSLQ+SLD+E +SR EV R+KKKME D
Sbjct: 1574 QLELLEAKAELERKLSEKDEEIENFRRKQQCTIDSLQSSLDSEAKSRIEVTRLKKKMEED 1633
Query: 1624 LNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLL 1683
LNEME+QLS ANR +EA K + LQ +KD Q+QLDD+ + N DLKE +A+ ERRN+LL
Sbjct: 1634 LNEMELQLSCANRQVSEATKSLGQLQIQIKDLQMQLDDSTQLNSDLKEQVAVAERRNSLL 1693
Query: 1684 QAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMESDLTQLQSEV 1743
Q+ELE+LR++ EQTER R+L+E+EL+E +ER+ L ++QNTSL++QKKK+E+D+ ++Q E
Sbjct: 1694 QSELEDLRSLQEQTERGRRLSEEELLEATERINLFYTQNTSLLSQKKKLEADVARMQKEA 1753
Query: 1744 EEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAE 1803
EE VQEC+NAEEKAKKA +AA ++EELKK+QDT AHLER ++NMEQTI DLQ RL EAE
Sbjct: 1754 EEVVQECQNAEEKAKKAAIEAANLSEELKKKQDTIAHLERTRENMEQTITDLQKRLAEAE 1813
Query: 1804 QIALKGGKKQLQKLEARVRELEGELEAEQKRNAESVKGMRKSERRIKELTYQTEEDKKNL 1863
Q+AL G +KQ+QKLE+RVRELEGELE E +R+AE+ +G R+ ER IKELTYQ EEDKKNL
Sbjct: 1814 QMALMGSRKQIQKLESRVRELEGELEGEIRRSAEAQRGARRLERCIKELTYQAEEDKKNL 1873
Query: 1864 LRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLR 1923
R+Q +DKLQLKV+ YK+Q E AE QAN LSK++K QHEL+E +ERA++AESQVNKL+
Sbjct: 1874 SRMQTQMDKLQLKVQNYKQQVEVAETQANQYLSKYKKQQHELNEVKERAEVAESQVNKLK 1933
Query: 1924 AKSRDIGAK 1932
K+R+ G K
Sbjct: 1934 IKAREFGKK 1942
Score = 35.4 bits (80), Expect = 0.55
Identities = 38/149 (25%), Positives = 66/149 (44%), Gaps = 4/149 (2%)
Query: 1792 IKDLQHRLDEAEQIA-LKGGKKQLQKLEARVRELEGELEAEQKRNAESVKGMRKSERRIK 1850
IK L + E++A LK QLQK + EL+A+Q + + + +
Sbjct: 848 IKPLVKSSEVGEEVAGLKEECAQLQKALEKSEFQREELKAKQVSLTQEKNDLILQLQAEQ 907
Query: 1851 ELTYQTEEDKKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEE 1910
E EE + L++ + +L+ +VK + EE EE + ++ RK++ E E ++
Sbjct: 908 ETLANVEEQCEWLIKSKI---QLEARVKELSERVEEEEEINSELTARGRKLEDECFELKK 964
Query: 1911 RADIAESQVNKLRAKSRDIGAKQKMHDEE 1939
D E+ + K + R K K EE
Sbjct: 965 EIDDLETMLVKSEKEKRTTEHKVKNLTEE 993
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 1432 bits (3706), Expect = 0.0
Identities = 783/1903 (41%), Positives = 1173/1903 (61%), Gaps = 23/1903 (1%)
Query: 38 FVPDDKEEFVKAKILSREGGKVIAE-TENGKTVTVKEDQVLQQNPPKFDKIEDMAMLTFL 96
+VP +K+ F A I +G +V+ E ENGK VTV +D + + NPPKF K+EDMA LT L
Sbjct: 37 WVPSEKQGFEAASIKEEKGDEVVVELVENGKKVTVGKDDIQKMNPPKFSKVEDMAELTCL 96
Query: 97 HEPAVLFNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNAEVVAAYRGKKRSEAPPHIFS 156
+E +VL NL+ERY + +IYTYSGLFCV VNPYK LP+Y+ ++V Y+GKKR E PPHI++
Sbjct: 97 NEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKRHEMPPHIYA 156
Query: 157 ISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFASIAAIGDRGKKDNANANKGT 216
I+D AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY A +A+ +GKKD + G
Sbjct: 157 IADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVAS-SHKGKKDTSIT--GE 213
Query: 217 LEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLEKSRVIF 276
LE Q++QANP LEAFGNAKTV+NDNSSRFGKFIRI+F TG + A+IETYLLEKSR I
Sbjct: 214 LEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAIR 273
Query: 277 QLKAERNYHIFYQILSNKKPELL-DMLLVTNNPYDYAFVSQGEVSVASIDDSEELMATDS 335
Q + ER +HIFY +++ K ++ D+LL N +Y F+S G V + + D E T
Sbjct: 274 QARDERTFHIFYYMIAGAKEKMRSDLLLEGFN--NYTFLSNGFVPIPAAQDDEMFQETVE 331
Query: 336 AFDVLGFTSEEKAGVYKLTGAIMHYGNMKFKQKQREEQAEPDGTEDADKSAYLMGLNSAD 395
A ++GF+ EE+ + K+ +++ GN+ FK+++ +QA A K +LMG+N D
Sbjct: 332 AMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKVCHLMGINVTD 391
Query: 396 LLKGLCHPRVKVGNEYVTKGQSVQQVYYSIGALAKAVYEKMFNWMVTRINATLE-TKQPR 454
+ + PR+KVG + V K Q+ +Q +++ ALAKA YE++F W++TR+N L+ T +
Sbjct: 392 FTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRVNKALDKTHRQG 451
Query: 455 QYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDF 514
F+G+LDIAGFEIF+ NSFEQLCIN+TNEKLQQ FNH MF+LEQEEY++EGIEW FIDF
Sbjct: 452 ASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDF 511
Query: 515 GMDLQACIDLIEKPM---GIMSILEEECMFPKATDMTFKAKLYDNHLGKSNNFQKPRNIK 571
G+DLQ CI+LIE+P G++++L+EEC FPKATD +F KL G FQKP+ +K
Sbjct: 512 GLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQ-GSHPKFQKPKQLK 570
Query: 572 GKQEAHFSLIHYAGTVDYNILGWLEKNKDPLNETVVALYQKSSLKLMATLFSSY------ 625
K E FS+IHYAG VDYN WL KN DPLN+ V +L SS K +A L+
Sbjct: 571 DKTE--FSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLWKDVDRIVGL 628
Query: 626 -ATADTGDSGKSKGGKKKGSSFQTVSALHRENLNKLMTNLRTTHPHFVRCIIPNERKAPG 684
A +S K K F+TV L++E L KLMT LR T P+FVRCIIPN K G
Sbjct: 629 DQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCIIPNHEKRSG 688
Query: 685 VMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRILNPVAIPEGQFIDSRKGT 744
+D LV+ QLRCNGVLEGIRICR+GFPNRI++ +FRQRY IL AIP+G F+D ++
Sbjct: 689 KLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKG-FMDGKQAC 747
Query: 745 EKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLSRIITRMQAQARGQLMRIEFK 804
++ +L++D N Y+ G +K+FF+ G+L LEE RD +++ +I QA RG L R F
Sbjct: 748 ILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRGYLARKAFA 807
Query: 805 KIVERRDALLVIQWNIRAFMGVKNWPWMKLYFKIKPLLKSAETEKEMATMKEEFGRIKET 864
K ++ A+ VIQ N A++ ++NW W +L+ K+KPLL+ E+EM ++E + KE
Sbjct: 808 KRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKEDELQKTKER 867
Query: 865 LEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLNDAEERCDQLIKNKIQLEAKVKEM 924
+K+E KELE+K L +EKN LQ Q+QAE + +AEE +L K +LE + EM
Sbjct: 868 QQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEM 927
Query: 925 NERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEM 984
RLE+EE+ +L A+++K+ + +L++ +++ E K++ EK E K+K L +E+
Sbjct: 928 EARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEI 987
Query: 985 AGLDEIIAKLTKEKKALQEAHQQALDDLQVEEDKVNSLSKSKVKLEQQVDDLEGSLEQEK 1044
+D+ KL+KE+K L+E +L EE+K +L+K K K E + +LE L++E+
Sbjct: 988 LVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEE 1047
Query: 1045 KVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQVLAL 1104
K R +LE+ KRKLEGD E I DL+ +L+ +L KKE ++ ++++DE
Sbjct: 1048 KSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKN 1107
Query: 1105 QLQKKLKENQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIE 1164
KK++E + I +L+E+L++ER AR K EK + DL ELE + LE+ +T+ Q E
Sbjct: 1108 NALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQE 1167
Query: 1165 MNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKS 1224
+ KRE E +++ L+E T HEA +R+KHA +V EL EQ++ +R K L+K K
Sbjct: 1168 LRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQ 1227
Query: 1225 EFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQT 1284
+ E D+ + + +AK +E + LE Q E + K + +R+ + + KLQ
Sbjct: 1228 TLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQN 1287
Query: 1285 ENGELARQLEEKEALISQLTRGKLSYTQQMEDLKRQLEEEGKAKNALAHALQSARHDCDL 1344
E + L E E +L + S + Q++D + L+EE + K ++ L+ + +
Sbjct: 1288 EVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNS 1347
Query: 1345 LREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEE 1404
L++Q +EE EAK L+R +S N +++ + K + D E LEE KK+ + +++ +
Sbjct: 1348 LQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQ-DFASTVEALEEGKKRFQKEIENLTQ 1406
Query: 1405 AVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEE 1464
E A LEKTK+RLQ E++DL+VD++ + L+KKQR FD++LAE K +
Sbjct: 1407 QYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSK 1466
Query: 1465 SQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGKN 1524
E + ++ EAR T+ L A EE+LE E +R NK L+ E+ DL + GKN
Sbjct: 1467 YADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKN 1526
Query: 1525 VHELEKVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEE 1584
VHELEK ++ LE + E+++ LEE E L+ E LR ++ +K + ER L +DE+
Sbjct: 1527 VHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQ 1586
Query: 1585 MEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLNEMEIQLSHANRMAAEAQKQ 1644
E+ +R QR + +T L+ E + R KKK+EGDL ++E+Q A + EA KQ
Sbjct: 1587 NEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQ 1646
Query: 1645 VKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLA 1704
++ LQ+ +KD Q +L+DA + D++ E++ L+A+L +L+ + ER+RK A
Sbjct: 1647 LRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQA 1706
Query: 1705 EQELIETSERVQLLHSQNTSLINQKKKMESDLTQLQSEVEEAVQECRNAEEKAKKAITDA 1764
+ E E +E + S +L ++K+++E+ + QL+ E+EE ++ +KA A
Sbjct: 1707 DLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQA 1766
Query: 1765 AMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVREL 1824
++ EL E+ T+ E ++ +E+ K+L+ +L E E K + LEA++ +L
Sbjct: 1767 EQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQL 1826
Query: 1825 EGELEAEQKRNAESVKGMRKSERRIKELTYQTEEDKKNLLRLQDLVDKLQLKVKAYKRQA 1884
E ++E E + + K +++ ++++KE+ Q E+++K + ++ +K +VK KRQ
Sbjct: 1827 EEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQL 1886
Query: 1885 EEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSR 1927
EEAEE++ + RK+Q ELDEA E + +VN L++K R
Sbjct: 1887 EEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLR 1929
Score = 221 bits (563), Expect = 5e-57
Identities = 195/960 (20%), Positives = 445/960 (46%), Gaps = 69/960 (7%)
Query: 995 TKEKKALQEAHQQALDDLQVEEDKVNSLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAK 1054
TK K LQ Q+ +++Q +ED++ + + K E ++ +LE Q L K
Sbjct: 839 TKVKPLLQVTRQE--EEMQAKEDELQKTKERQQKAENELKELEQKHSQ-------LTEEK 889
Query: 1055 RKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQVLALQLQKKLKENQ 1114
L+ L+ E + E +++L K ++ E +++ +++E+E+ QLQ + K+
Sbjct: 890 NLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMA 949
Query: 1115 ARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQ 1174
++ +LEE+LE E AR K++ + +++++ + + V + N K E +
Sbjct: 950 QQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEI-------LVMDDQNNKLSKERK 1002
Query: 1175 KMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVT 1234
+ + + T ++AE E+ NL ++K K E SE ++ L
Sbjct: 1003 LLEERISDLTT---------------NLAEEEEKAKNLTKLKNKHESMISELEVRL---- 1043
Query: 1235 SNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQTENGELARQLE 1294
++ K++ LEK+ R LE A+++ ++ + Q + + Q AK + E +L+
Sbjct: 1044 ---KKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLD 1100
Query: 1295 EKEALISQLTRGKLSYTQQMEDLKRQLEEEGKAKNALAHALQSARHDCDLLREQYEEETE 1354
++ A + + + DL+ L+ E A+N + + + L+ + E+ +
Sbjct: 1101 DEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLD 1160
Query: 1355 AKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCS 1414
+ A Q + +K EV + + + +++E ++K AQ +++ E +E +
Sbjct: 1161 STATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKA 1220
Query: 1415 SLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQK 1474
+L+K K L+ E DL ++ A ++ K++ + + +E QS+ ++
Sbjct: 1221 NLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEA-------QVQELQSKCSDGER 1273
Query: 1475 EARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGKNVHELEKVR-- 1532
L+ ++ KL+N E L + + L ++++ L+ QL + + + E + +
Sbjct: 1274 ARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLN 1333
Query: 1533 -----KQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQ 1587
+QLE E+ LQ L+E + ++ E I ++ + K +++ A E +E+
Sbjct: 1334 VSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQ-DFASTVEALEE 1392
Query: 1588 AKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKS 1647
K+ Q+ +++L + + + +++ + K +++ +L+++ + L + ++ + +K+ +
Sbjct: 1393 GKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRK 1452
Query: 1648 LQSLLKD----TQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKL 1703
LL + + D+ RA + +E E + L LEE E+ ER+ K+
Sbjct: 1453 FDQLLAEEKNISSKYADERDRAEAEAREK----ETKALSLARALEEALEAKEELERTNKM 1508
Query: 1704 AEQELIETSERVQLLHSQNTSLINQKKKMESDLTQLQSEVEEAVQECRNAEE-KAKKAIT 1762
+ E+ + + L K+ +E+ + ++++++EE E + E+ K + +
Sbjct: 1509 LKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVN 1568
Query: 1763 DAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRL-DEAEQIALKGGKKQLQKLEARV 1821
A+ + + Q E ++ +++ + + + L DE +Q AL K+ KLE +
Sbjct: 1569 MQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKK--KLEGDL 1626
Query: 1822 RELEGELEAEQKRNAESVKGMRKSERRIKELTYQTEEDKKNLLRLQDLVDKLQLKVKAYK 1881
++LE + ++ K E++K +RK + ++K+ +Q E + R + + + KA
Sbjct: 1627 KDLELQADSAIKGREEAIKQLRKLQAQMKD--FQRELEDARASRDEIFATAKENEKKAKS 1684
Query: 1882 RQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQV--NKLRAKSRDIGAKQKMHDEE 1939
+A+ + Q + ++ + Q +L++ E ++A S N L+ + R + A+ +EE
Sbjct: 1685 LEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEE 1744
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 1432 bits (3706), Expect = 0.0
Identities = 783/1903 (41%), Positives = 1173/1903 (61%), Gaps = 23/1903 (1%)
Query: 38 FVPDDKEEFVKAKILSREGGKVIAE-TENGKTVTVKEDQVLQQNPPKFDKIEDMAMLTFL 96
+VP +K+ F A I +G +V+ E ENGK VTV +D + + NPPKF K+EDMA LT L
Sbjct: 37 WVPSEKQGFEAASIKEEKGDEVVVELVENGKKVTVGKDDIQKMNPPKFSKVEDMAELTCL 96
Query: 97 HEPAVLFNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNAEVVAAYRGKKRSEAPPHIFS 156
+E +VL NL+ERY + +IYTYSGLFCV VNPYK LP+Y+ ++V Y+GKKR E PPHI++
Sbjct: 97 NEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKRHEMPPHIYA 156
Query: 157 ISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFASIAAIGDRGKKDNANANKGT 216
I+D AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY A +A+ +GKKD + G
Sbjct: 157 IADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVAS-SHKGKKDTSIT--GE 213
Query: 217 LEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLEKSRVIF 276
LE Q++QANP LEAFGNAKTV+NDNSSRFGKFIRI+F TG + A+IETYLLEKSR I
Sbjct: 214 LEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAIR 273
Query: 277 QLKAERNYHIFYQILSNKKPELL-DMLLVTNNPYDYAFVSQGEVSVASIDDSEELMATDS 335
Q + ER +HIFY +++ K ++ D+LL N +Y F+S G V + + D E T
Sbjct: 274 QARDERTFHIFYYMIAGAKEKMRSDLLLEGFN--NYTFLSNGFVPIPAAQDDEMFQETVE 331
Query: 336 AFDVLGFTSEEKAGVYKLTGAIMHYGNMKFKQKQREEQAEPDGTEDADKSAYLMGLNSAD 395
A ++GF+ EE+ + K+ +++ GN+ FK+++ +QA A K +LMG+N D
Sbjct: 332 AMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKVCHLMGINVTD 391
Query: 396 LLKGLCHPRVKVGNEYVTKGQSVQQVYYSIGALAKAVYEKMFNWMVTRINATLE-TKQPR 454
+ + PR+KVG + V K Q+ +Q +++ ALAKA YE++F W++TR+N L+ T +
Sbjct: 392 FTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRVNKALDKTHRQG 451
Query: 455 QYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDF 514
F+G+LDIAGFEIF+ NSFEQLCIN+TNEKLQQ FNH MF+LEQEEY++EGIEW FIDF
Sbjct: 452 ASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDF 511
Query: 515 GMDLQACIDLIEKPM---GIMSILEEECMFPKATDMTFKAKLYDNHLGKSNNFQKPRNIK 571
G+DLQ CI+LIE+P G++++L+EEC FPKATD +F KL G FQKP+ +K
Sbjct: 512 GLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQ-GSHPKFQKPKQLK 570
Query: 572 GKQEAHFSLIHYAGTVDYNILGWLEKNKDPLNETVVALYQKSSLKLMATLFSSY------ 625
K E FS+IHYAG VDYN WL KN DPLN+ V +L SS K +A L+
Sbjct: 571 DKTE--FSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLWKDVDRIVGL 628
Query: 626 -ATADTGDSGKSKGGKKKGSSFQTVSALHRENLNKLMTNLRTTHPHFVRCIIPNERKAPG 684
A +S K K F+TV L++E L KLMT LR T P+FVRCIIPN K G
Sbjct: 629 DQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCIIPNHEKRSG 688
Query: 685 VMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRILNPVAIPEGQFIDSRKGT 744
+D LV+ QLRCNGVLEGIRICR+GFPNRI++ +FRQRY IL AIP+G F+D ++
Sbjct: 689 KLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKG-FMDGKQAC 747
Query: 745 EKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLSRIITRMQAQARGQLMRIEFK 804
++ +L++D N Y+ G +K+FF+ G+L LEE RD +++ +I QA RG L R F
Sbjct: 748 ILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRGYLARKAFA 807
Query: 805 KIVERRDALLVIQWNIRAFMGVKNWPWMKLYFKIKPLLKSAETEKEMATMKEEFGRIKET 864
K ++ A+ VIQ N A++ ++NW W +L+ K+KPLL+ E+EM ++E + KE
Sbjct: 808 KRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKEDELQKTKER 867
Query: 865 LEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLNDAEERCDQLIKNKIQLEAKVKEM 924
+K+E KELE+K L +EKN LQ Q+QAE + +AEE +L K +LE + EM
Sbjct: 868 QQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEM 927
Query: 925 NERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEM 984
RLE+EE+ +L A+++K+ + +L++ +++ E K++ EK E K+K L +E+
Sbjct: 928 EARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEI 987
Query: 985 AGLDEIIAKLTKEKKALQEAHQQALDDLQVEEDKVNSLSKSKVKLEQQVDDLEGSLEQEK 1044
+D+ KL+KE+K L+E +L EE+K +L+K K K E + +LE L++E+
Sbjct: 988 LVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEE 1047
Query: 1045 KVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQVLAL 1104
K R +LE+ KRKLEGD E I DL+ +L+ +L KKE ++ ++++DE
Sbjct: 1048 KSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKN 1107
Query: 1105 QLQKKLKENQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIE 1164
KK++E + I +L+E+L++ER AR K EK + DL ELE + LE+ +T+ Q E
Sbjct: 1108 NALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQE 1167
Query: 1165 MNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKS 1224
+ KRE E +++ L+E T HEA +R+KHA +V EL EQ++ +R K L+K K
Sbjct: 1168 LRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQ 1227
Query: 1225 EFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQT 1284
+ E D+ + + +AK +E + LE Q E + K + +R+ + + KLQ
Sbjct: 1228 TLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQN 1287
Query: 1285 ENGELARQLEEKEALISQLTRGKLSYTQQMEDLKRQLEEEGKAKNALAHALQSARHDCDL 1344
E + L E E +L + S + Q++D + L+EE + K ++ L+ + +
Sbjct: 1288 EVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNS 1347
Query: 1345 LREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEE 1404
L++Q +EE EAK L+R +S N +++ + K + D E LEE KK+ + +++ +
Sbjct: 1348 LQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQ-DFASTVEALEEGKKRFQKEIENLTQ 1406
Query: 1405 AVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEE 1464
E A LEKTK+RLQ E++DL+VD++ + L+KKQR FD++LAE K +
Sbjct: 1407 QYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSK 1466
Query: 1465 SQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGKN 1524
E + ++ EAR T+ L A EE+LE E +R NK L+ E+ DL + GKN
Sbjct: 1467 YADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKN 1526
Query: 1525 VHELEKVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEE 1584
VHELEK ++ LE + E+++ LEE E L+ E LR ++ +K + ER L +DE+
Sbjct: 1527 VHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQ 1586
Query: 1585 MEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLNEMEIQLSHANRMAAEAQKQ 1644
E+ +R QR + +T L+ E + R KKK+EGDL ++E+Q A + EA KQ
Sbjct: 1587 NEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQ 1646
Query: 1645 VKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLA 1704
++ LQ+ +KD Q +L+DA + D++ E++ L+A+L +L+ + ER+RK A
Sbjct: 1647 LRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQA 1706
Query: 1705 EQELIETSERVQLLHSQNTSLINQKKKMESDLTQLQSEVEEAVQECRNAEEKAKKAITDA 1764
+ E E +E + S +L ++K+++E+ + QL+ E+EE ++ +KA A
Sbjct: 1707 DLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQA 1766
Query: 1765 AMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVREL 1824
++ EL E+ T+ E ++ +E+ K+L+ +L E E K + LEA++ +L
Sbjct: 1767 EQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQL 1826
Query: 1825 EGELEAEQKRNAESVKGMRKSERRIKELTYQTEEDKKNLLRLQDLVDKLQLKVKAYKRQA 1884
E ++E E + + K +++ ++++KE+ Q E+++K + ++ +K +VK KRQ
Sbjct: 1827 EEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQL 1886
Query: 1885 EEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSR 1927
EEAEE++ + RK+Q ELDEA E + +VN L++K R
Sbjct: 1887 EEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLR 1929
Score = 221 bits (563), Expect = 5e-57
Identities = 195/960 (20%), Positives = 445/960 (46%), Gaps = 69/960 (7%)
Query: 995 TKEKKALQEAHQQALDDLQVEEDKVNSLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAK 1054
TK K LQ Q+ +++Q +ED++ + + K E ++ +LE Q L K
Sbjct: 839 TKVKPLLQVTRQE--EEMQAKEDELQKTKERQQKAENELKELEQKHSQ-------LTEEK 889
Query: 1055 RKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQVLALQLQKKLKENQ 1114
L+ L+ E + E +++L K ++ E +++ +++E+E+ QLQ + K+
Sbjct: 890 NLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMA 949
Query: 1115 ARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQ 1174
++ +LEE+LE E AR K++ + +++++ + + V + N K E +
Sbjct: 950 QQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEI-------LVMDDQNNKLSKERK 1002
Query: 1175 KMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVT 1234
+ + + T ++AE E+ NL ++K K E SE ++ L
Sbjct: 1003 LLEERISDLTT---------------NLAEEEEKAKNLTKLKNKHESMISELEVRL---- 1043
Query: 1235 SNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQTENGELARQLE 1294
++ K++ LEK+ R LE A+++ ++ + Q + + Q AK + E +L+
Sbjct: 1044 ---KKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLD 1100
Query: 1295 EKEALISQLTRGKLSYTQQMEDLKRQLEEEGKAKNALAHALQSARHDCDLLREQYEEETE 1354
++ A + + + DL+ L+ E A+N + + + L+ + E+ +
Sbjct: 1101 DEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLD 1160
Query: 1355 AKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCS 1414
+ A Q + +K EV + + + +++E ++K AQ +++ E +E +
Sbjct: 1161 STATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKA 1220
Query: 1415 SLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQK 1474
+L+K K L+ E DL ++ A ++ K++ + + +E QS+ ++
Sbjct: 1221 NLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEA-------QVQELQSKCSDGER 1273
Query: 1475 EARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGKNVHELEKVR-- 1532
L+ ++ KL+N E L + + L ++++ L+ QL + + + E + +
Sbjct: 1274 ARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLN 1333
Query: 1533 -----KQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQ 1587
+QLE E+ LQ L+E + ++ E I ++ + K +++ A E +E+
Sbjct: 1334 VSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQ-DFASTVEALEE 1392
Query: 1588 AKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKS 1647
K+ Q+ +++L + + + +++ + K +++ +L+++ + L + ++ + +K+ +
Sbjct: 1393 GKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRK 1452
Query: 1648 LQSLLKD----TQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKL 1703
LL + + D+ RA + +E E + L LEE E+ ER+ K+
Sbjct: 1453 FDQLLAEEKNISSKYADERDRAEAEAREK----ETKALSLARALEEALEAKEELERTNKM 1508
Query: 1704 AEQELIETSERVQLLHSQNTSLINQKKKMESDLTQLQSEVEEAVQECRNAEE-KAKKAIT 1762
+ E+ + + L K+ +E+ + ++++++EE E + E+ K + +
Sbjct: 1509 LKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVN 1568
Query: 1763 DAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRL-DEAEQIALKGGKKQLQKLEARV 1821
A+ + + Q E ++ +++ + + + L DE +Q AL K+ KLE +
Sbjct: 1569 MQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKK--KLEGDL 1626
Query: 1822 RELEGELEAEQKRNAESVKGMRKSERRIKELTYQTEEDKKNLLRLQDLVDKLQLKVKAYK 1881
++LE + ++ K E++K +RK + ++K+ +Q E + R + + + KA
Sbjct: 1627 KDLELQADSAIKGREEAIKQLRKLQAQMKD--FQRELEDARASRDEIFATAKENEKKAKS 1684
Query: 1882 RQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQV--NKLRAKSRDIGAKQKMHDEE 1939
+A+ + Q + ++ + Q +L++ E ++A S N L+ + R + A+ +EE
Sbjct: 1685 LEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEE 1744
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 1430 bits (3701), Expect = 0.0
Identities = 783/1908 (41%), Positives = 1173/1908 (61%), Gaps = 26/1908 (1%)
Query: 38 FVPDDKEEFVKAKILSREGGKVIAE-TENGKTVTVKEDQVLQQNPPKFDKIEDMAMLTFL 96
+VP +K+ F A I +G +V+ E ENGK VTV +D + + NPPKF K+EDMA LT L
Sbjct: 37 WVPSEKQGFEAASIKEEKGDEVVVELVENGKKVTVGKDDIQKMNPPKFSKVEDMAELTCL 96
Query: 97 HEPAVLFNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNAEVVAAYRGKKRSEAPPHIFS 156
+E +VL NL+ERY + +IYTYSGLFCV VNPYK LP+Y+ ++V Y+GKKR E PPHI++
Sbjct: 97 NEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKRHEMPPHIYA 156
Query: 157 ISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFASIAAIGDRGKKDNANANK-- 214
I+D AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY A +A+ +GKKD +
Sbjct: 157 IADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVAS-SHKGKKDTSITQGPS 215
Query: 215 ---GTLEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLEK 271
G LE Q++QANP LEAFGNAKTV+NDNSSRFGKFIRI+F TG + A+IETYLLEK
Sbjct: 216 FAYGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEK 275
Query: 272 SRVIFQLKAERNYHIFYQILSNKKPELL-DMLLVTNNPYDYAFVSQGEVSVASIDDSEEL 330
SR I Q + ER +HIFY +++ K ++ D+LL N +Y F+S G V + + D E
Sbjct: 276 SRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFN--NYTFLSNGFVPIPAAQDDEMF 333
Query: 331 MATDSAFDVLGFTSEEKAGVYKLTGAIMHYGNMKFKQKQREEQAEPDGTEDADKSAYLMG 390
T A ++GF+ EE+ + K+ +++ GN+ FK+++ +QA A K +LMG
Sbjct: 334 QETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKVCHLMG 393
Query: 391 LNSADLLKGLCHPRVKVGNEYVTKGQSVQQVYYSIGALAKAVYEKMFNWMVTRINATLE- 449
+N D + + PR+KVG + V K Q+ +Q +++ ALAKA YE++F W++TR+N L+
Sbjct: 394 INVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRVNKALDK 453
Query: 450 TKQPRQYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEW 509
T + F+G+LDIAGFEIF+ NSFEQLCIN+TNEKLQQ FNH MF+LEQEEY++EGIEW
Sbjct: 454 THRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEW 513
Query: 510 TFIDFGMDLQACIDLIEKPM---GIMSILEEECMFPKATDMTFKAKLYDNHLGKSNNFQK 566
FIDFG+DLQ CI+LIE+P G++++L+EEC FPKATD +F KL G FQK
Sbjct: 514 NFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQ-GSHPKFQK 572
Query: 567 PRNIKGKQEAHFSLIHYAGTVDYNILGWLEKNKDPLNETVVALYQKSSLKLMATLFSSY- 625
P+ +K K E FS+IHYAG VDYN WL KN DPLN+ V +L SS K +A L+
Sbjct: 573 PKQLKDKTE--FSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLWKDVD 630
Query: 626 ------ATADTGDSGKSKGGKKKGSSFQTVSALHRENLNKLMTNLRTTHPHFVRCIIPNE 679
A +S K K F+TV L++E L KLMT LR T P+FVRCIIPN
Sbjct: 631 RIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCIIPNH 690
Query: 680 RKAPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRILNPVAIPEGQFID 739
K G +D LV+ QLRCNGVLEGIRICR+GFPNRI++ +FRQRY IL AIP+G F+D
Sbjct: 691 EKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKG-FMD 749
Query: 740 SRKGTEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLSRIITRMQAQARGQLM 799
++ ++ +L++D N Y+ G +K+FF+ G+L LEE RD +++ +I QA RG L
Sbjct: 750 GKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRGYLA 809
Query: 800 RIEFKKIVERRDALLVIQWNIRAFMGVKNWPWMKLYFKIKPLLKSAETEKEMATMKEEFG 859
R F K ++ A+ VIQ N A++ ++NW W +L+ K+KPLL+ E+EM ++E
Sbjct: 810 RKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKEDELQ 869
Query: 860 RIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLNDAEERCDQLIKNKIQLEA 919
+ KE +K+E KELE+K L +EKN LQ Q+QAE + +AEE +L K +LE
Sbjct: 870 KTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEE 929
Query: 920 KVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKN 979
+ EM RLE+EE+ +L A+++K+ + +L++ +++ E K++ EK E K+K
Sbjct: 930 ILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKK 989
Query: 980 LTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQVEEDKVNSLSKSKVKLEQQVDDLEGS 1039
L +E+ +D+ KL+KE+K L+E +L EE+K +L+K K K E + +LE
Sbjct: 990 LEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVR 1049
Query: 1040 LEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDE 1099
L++E+K R +LE+ KRKLEGD E I DL+ +L+ +L KKE ++ ++++DE
Sbjct: 1050 LKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDE 1109
Query: 1100 QVLALQLQKKLKENQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGAT 1159
KK++E + I +L+E+L++ER AR K EK + DL ELE + LE+ +T
Sbjct: 1110 IAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDST 1169
Query: 1160 SVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKL 1219
+ Q E+ KRE E +++ L+E T HEA +R+KHA +V EL EQ++ +R K L
Sbjct: 1170 ATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANL 1229
Query: 1220 EKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQR 1279
+K K + E D+ + + +AK +E + LE Q E + K + +R+ + +
Sbjct: 1230 DKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKV 1289
Query: 1280 AKLQTENGELARQLEEKEALISQLTRGKLSYTQQMEDLKRQLEEEGKAKNALAHALQSAR 1339
KLQ E + L E E +L + S + Q++D + L+EE + K ++ L+
Sbjct: 1290 HKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLE 1349
Query: 1340 HDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRL 1399
+ + L++Q +EE EAK L+R +S N +++ + K + D E LEE KK+ + +
Sbjct: 1350 EERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQ-DFASTVEALEEGKKRFQKEI 1408
Query: 1400 QDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWK 1459
++ + E A LEKTK+RLQ E++DL+VD++ + L+KKQR FD++LAE K
Sbjct: 1409 ENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEK 1468
Query: 1460 QKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLG 1519
+ E + ++ EAR T+ L A EE+LE E +R NK L+ E+ DL
Sbjct: 1469 NISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKD 1528
Query: 1520 EGGKNVHELEKVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLA 1579
+ GKNVHELEK ++ LE + E+++ LEE E L+ E LR ++ +K + ER L
Sbjct: 1529 DVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQ 1588
Query: 1580 EKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLNEMEIQLSHANRMAA 1639
+DE+ E+ +R QR + +T L+ E + R KKK+EGDL ++E+Q A +
Sbjct: 1589 ARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGRE 1648
Query: 1640 EAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTER 1699
EA KQ++ LQ+ +KD Q +L+DA + D++ E++ L+A+L +L+ + ER
Sbjct: 1649 EAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAER 1708
Query: 1700 SRKLAEQELIETSERVQLLHSQNTSLINQKKKMESDLTQLQSEVEEAVQECRNAEEKAKK 1759
+RK A+ E E +E + S +L ++K+++E+ + QL+ E+EE ++ +K
Sbjct: 1709 ARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRK 1768
Query: 1760 AITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEA 1819
A A ++ EL E+ T+ E ++ +E+ K+L+ +L E E K + LEA
Sbjct: 1769 ATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEA 1828
Query: 1820 RVRELEGELEAEQKRNAESVKGMRKSERRIKELTYQTEEDKKNLLRLQDLVDKLQLKVKA 1879
++ +LE ++E E + + K +++ ++++KE+ Q E+++K + ++ +K +VK
Sbjct: 1829 KIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQ 1888
Query: 1880 YKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSR 1927
KRQ EEAEE++ + RK+Q ELDEA E + +VN L++K R
Sbjct: 1889 LKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLR 1936
Score = 221 bits (563), Expect = 5e-57
Identities = 195/960 (20%), Positives = 445/960 (46%), Gaps = 69/960 (7%)
Query: 995 TKEKKALQEAHQQALDDLQVEEDKVNSLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAK 1054
TK K LQ Q+ +++Q +ED++ + + K E ++ +LE Q L K
Sbjct: 846 TKVKPLLQVTRQE--EEMQAKEDELQKTKERQQKAENELKELEQKHSQ-------LTEEK 896
Query: 1055 RKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQVLALQLQKKLKENQ 1114
L+ L+ E + E +++L K ++ E +++ +++E+E+ QLQ + K+
Sbjct: 897 NLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMA 956
Query: 1115 ARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQ 1174
++ +LEE+LE E AR K++ + +++++ + + V + N K E +
Sbjct: 957 QQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEI-------LVMDDQNNKLSKERK 1009
Query: 1175 KMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVT 1234
+ + + T ++AE E+ NL ++K K E SE ++ L
Sbjct: 1010 LLEERISDLTT---------------NLAEEEEKAKNLTKLKNKHESMISELEVRL---- 1050
Query: 1235 SNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQTENGELARQLE 1294
++ K++ LEK+ R LE A+++ ++ + Q + + Q AK + E +L+
Sbjct: 1051 ---KKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLD 1107
Query: 1295 EKEALISQLTRGKLSYTQQMEDLKRQLEEEGKAKNALAHALQSARHDCDLLREQYEEETE 1354
++ A + + + DL+ L+ E A+N + + + L+ + E+ +
Sbjct: 1108 DEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLD 1167
Query: 1355 AKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCS 1414
+ A Q + +K EV + + + +++E ++K AQ +++ E +E +
Sbjct: 1168 STATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKA 1227
Query: 1415 SLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQK 1474
+L+K K L+ E DL ++ A ++ K++ + + +E QS+ ++
Sbjct: 1228 NLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEA-------QVQELQSKCSDGER 1280
Query: 1475 EARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGKNVHELEKVR-- 1532
L+ ++ KL+N E L + + L ++++ L+ QL + + + E + +
Sbjct: 1281 ARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLN 1340
Query: 1533 -----KQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQ 1587
+QLE E+ LQ L+E + ++ E I ++ + K +++ A E +E+
Sbjct: 1341 VSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQ-DFASTVEALEE 1399
Query: 1588 AKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKS 1647
K+ Q+ +++L + + + +++ + K +++ +L+++ + L + ++ + +K+ +
Sbjct: 1400 GKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRK 1459
Query: 1648 LQSLLKD----TQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKL 1703
LL + + D+ RA + +E E + L LEE E+ ER+ K+
Sbjct: 1460 FDQLLAEEKNISSKYADERDRAEAEAREK----ETKALSLARALEEALEAKEELERTNKM 1515
Query: 1704 AEQELIETSERVQLLHSQNTSLINQKKKMESDLTQLQSEVEEAVQECRNAEE-KAKKAIT 1762
+ E+ + + L K+ +E+ + ++++++EE E + E+ K + +
Sbjct: 1516 LKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVN 1575
Query: 1763 DAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRL-DEAEQIALKGGKKQLQKLEARV 1821
A+ + + Q E ++ +++ + + + L DE +Q AL K+ KLE +
Sbjct: 1576 MQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKK--KLEGDL 1633
Query: 1822 RELEGELEAEQKRNAESVKGMRKSERRIKELTYQTEEDKKNLLRLQDLVDKLQLKVKAYK 1881
++LE + ++ K E++K +RK + ++K+ +Q E + R + + + KA
Sbjct: 1634 KDLELQADSAIKGREEAIKQLRKLQAQMKD--FQRELEDARASRDEIFATAKENEKKAKS 1691
Query: 1882 RQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQV--NKLRAKSRDIGAKQKMHDEE 1939
+A+ + Q + ++ + Q +L++ E ++A S N L+ + R + A+ +EE
Sbjct: 1692 LEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEE 1751
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 1430 bits (3701), Expect = 0.0
Identities = 783/1908 (41%), Positives = 1173/1908 (61%), Gaps = 26/1908 (1%)
Query: 38 FVPDDKEEFVKAKILSREGGKVIAE-TENGKTVTVKEDQVLQQNPPKFDKIEDMAMLTFL 96
+VP +K+ F A I +G +V+ E ENGK VTV +D + + NPPKF K+EDMA LT L
Sbjct: 37 WVPSEKQGFEAASIKEEKGDEVVVELVENGKKVTVGKDDIQKMNPPKFSKVEDMAELTCL 96
Query: 97 HEPAVLFNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNAEVVAAYRGKKRSEAPPHIFS 156
+E +VL NL+ERY + +IYTYSGLFCV VNPYK LP+Y+ ++V Y+GKKR E PPHI++
Sbjct: 97 NEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKRHEMPPHIYA 156
Query: 157 ISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFASIAAIGDRGKKDNANANK-- 214
I+D AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY A +A+ +GKKD +
Sbjct: 157 IADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVAS-SHKGKKDTSITQGPS 215
Query: 215 ---GTLEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLEK 271
G LE Q++QANP LEAFGNAKTV+NDNSSRFGKFIRI+F TG + A+IETYLLEK
Sbjct: 216 FAYGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEK 275
Query: 272 SRVIFQLKAERNYHIFYQILSNKKPELL-DMLLVTNNPYDYAFVSQGEVSVASIDDSEEL 330
SR I Q + ER +HIFY +++ K ++ D+LL N +Y F+S G V + + D E
Sbjct: 276 SRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFN--NYTFLSNGFVPIPAAQDDEMF 333
Query: 331 MATDSAFDVLGFTSEEKAGVYKLTGAIMHYGNMKFKQKQREEQAEPDGTEDADKSAYLMG 390
T A ++GF+ EE+ + K+ +++ GN+ FK+++ +QA A K +LMG
Sbjct: 334 QETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKVCHLMG 393
Query: 391 LNSADLLKGLCHPRVKVGNEYVTKGQSVQQVYYSIGALAKAVYEKMFNWMVTRINATLE- 449
+N D + + PR+KVG + V K Q+ +Q +++ ALAKA YE++F W++TR+N L+
Sbjct: 394 INVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRVNKALDK 453
Query: 450 TKQPRQYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEW 509
T + F+G+LDIAGFEIF+ NSFEQLCIN+TNEKLQQ FNH MF+LEQEEY++EGIEW
Sbjct: 454 THRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEW 513
Query: 510 TFIDFGMDLQACIDLIEKPM---GIMSILEEECMFPKATDMTFKAKLYDNHLGKSNNFQK 566
FIDFG+DLQ CI+LIE+P G++++L+EEC FPKATD +F KL G FQK
Sbjct: 514 NFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQ-GSHPKFQK 572
Query: 567 PRNIKGKQEAHFSLIHYAGTVDYNILGWLEKNKDPLNETVVALYQKSSLKLMATLFSSY- 625
P+ +K K E FS+IHYAG VDYN WL KN DPLN+ V +L SS K +A L+
Sbjct: 573 PKQLKDKTE--FSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLWKDVD 630
Query: 626 ------ATADTGDSGKSKGGKKKGSSFQTVSALHRENLNKLMTNLRTTHPHFVRCIIPNE 679
A +S K K F+TV L++E L KLMT LR T P+FVRCIIPN
Sbjct: 631 RIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCIIPNH 690
Query: 680 RKAPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRILNPVAIPEGQFID 739
K G +D LV+ QLRCNGVLEGIRICR+GFPNRI++ +FRQRY IL AIP+G F+D
Sbjct: 691 EKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKG-FMD 749
Query: 740 SRKGTEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLSRIITRMQAQARGQLM 799
++ ++ +L++D N Y+ G +K+FF+ G+L LEE RD +++ +I QA RG L
Sbjct: 750 GKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRGYLA 809
Query: 800 RIEFKKIVERRDALLVIQWNIRAFMGVKNWPWMKLYFKIKPLLKSAETEKEMATMKEEFG 859
R F K ++ A+ VIQ N A++ ++NW W +L+ K+KPLL+ E+EM ++E
Sbjct: 810 RKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKEDELQ 869
Query: 860 RIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLNDAEERCDQLIKNKIQLEA 919
+ KE +K+E KELE+K L +EKN LQ Q+QAE + +AEE +L K +LE
Sbjct: 870 KTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEE 929
Query: 920 KVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKN 979
+ EM RLE+EE+ +L A+++K+ + +L++ +++ E K++ EK E K+K
Sbjct: 930 ILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKK 989
Query: 980 LTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQVEEDKVNSLSKSKVKLEQQVDDLEGS 1039
L +E+ +D+ KL+KE+K L+E +L EE+K +L+K K K E + +LE
Sbjct: 990 LEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVR 1049
Query: 1040 LEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDE 1099
L++E+K R +LE+ KRKLEGD E I DL+ +L+ +L KKE ++ ++++DE
Sbjct: 1050 LKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDE 1109
Query: 1100 QVLALQLQKKLKENQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGAT 1159
KK++E + I +L+E+L++ER AR K EK + DL ELE + LE+ +T
Sbjct: 1110 IAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDST 1169
Query: 1160 SVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKL 1219
+ Q E+ KRE E +++ L+E T HEA +R+KHA +V EL EQ++ +R K L
Sbjct: 1170 ATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANL 1229
Query: 1220 EKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQR 1279
+K K + E D+ + + +AK +E + LE Q E + K + +R+ + +
Sbjct: 1230 DKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKV 1289
Query: 1280 AKLQTENGELARQLEEKEALISQLTRGKLSYTQQMEDLKRQLEEEGKAKNALAHALQSAR 1339
KLQ E + L E E +L + S + Q++D + L+EE + K ++ L+
Sbjct: 1290 HKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLE 1349
Query: 1340 HDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRL 1399
+ + L++Q +EE EAK L+R +S N +++ + K + D E LEE KK+ + +
Sbjct: 1350 EERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQ-DFASTVEALEEGKKRFQKEI 1408
Query: 1400 QDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWK 1459
++ + E A LEKTK+RLQ E++DL+VD++ + L+KKQR FD++LAE K
Sbjct: 1409 ENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEK 1468
Query: 1460 QKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLG 1519
+ E + ++ EAR T+ L A EE+LE E +R NK L+ E+ DL
Sbjct: 1469 NISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKD 1528
Query: 1520 EGGKNVHELEKVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLA 1579
+ GKNVHELEK ++ LE + E+++ LEE E L+ E LR ++ +K + ER L
Sbjct: 1529 DVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQ 1588
Query: 1580 EKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLNEMEIQLSHANRMAA 1639
+DE+ E+ +R QR + +T L+ E + R KKK+EGDL ++E+Q A +
Sbjct: 1589 ARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGRE 1648
Query: 1640 EAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTER 1699
EA KQ++ LQ+ +KD Q +L+DA + D++ E++ L+A+L +L+ + ER
Sbjct: 1649 EAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAER 1708
Query: 1700 SRKLAEQELIETSERVQLLHSQNTSLINQKKKMESDLTQLQSEVEEAVQECRNAEEKAKK 1759
+RK A+ E E +E + S +L ++K+++E+ + QL+ E+EE ++ +K
Sbjct: 1709 ARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRK 1768
Query: 1760 AITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEA 1819
A A ++ EL E+ T+ E ++ +E+ K+L+ +L E E K + LEA
Sbjct: 1769 ATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEA 1828
Query: 1820 RVRELEGELEAEQKRNAESVKGMRKSERRIKELTYQTEEDKKNLLRLQDLVDKLQLKVKA 1879
++ +LE ++E E + + K +++ ++++KE+ Q E+++K + ++ +K +VK
Sbjct: 1829 KIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQ 1888
Query: 1880 YKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSR 1927
KRQ EEAEE++ + RK+Q ELDEA E + +VN L++K R
Sbjct: 1889 LKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLR 1936
Score = 221 bits (563), Expect = 5e-57
Identities = 195/960 (20%), Positives = 445/960 (46%), Gaps = 69/960 (7%)
Query: 995 TKEKKALQEAHQQALDDLQVEEDKVNSLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAK 1054
TK K LQ Q+ +++Q +ED++ + + K E ++ +LE Q L K
Sbjct: 846 TKVKPLLQVTRQE--EEMQAKEDELQKTKERQQKAENELKELEQKHSQ-------LTEEK 896
Query: 1055 RKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQVLALQLQKKLKENQ 1114
L+ L+ E + E +++L K ++ E +++ +++E+E+ QLQ + K+
Sbjct: 897 NLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMA 956
Query: 1115 ARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQ 1174
++ +LEE+LE E AR K++ + +++++ + + V + N K E +
Sbjct: 957 QQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEI-------LVMDDQNNKLSKERK 1009
Query: 1175 KMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVT 1234
+ + + T ++AE E+ NL ++K K E SE ++ L
Sbjct: 1010 LLEERISDLTT---------------NLAEEEEKAKNLTKLKNKHESMISELEVRL---- 1050
Query: 1235 SNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQTENGELARQLE 1294
++ K++ LEK+ R LE A+++ ++ + Q + + Q AK + E +L+
Sbjct: 1051 ---KKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLD 1107
Query: 1295 EKEALISQLTRGKLSYTQQMEDLKRQLEEEGKAKNALAHALQSARHDCDLLREQYEEETE 1354
++ A + + + DL+ L+ E A+N + + + L+ + E+ +
Sbjct: 1108 DEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLD 1167
Query: 1355 AKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCS 1414
+ A Q + +K EV + + + +++E ++K AQ +++ E +E +
Sbjct: 1168 STATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKA 1227
Query: 1415 SLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQK 1474
+L+K K L+ E DL ++ A ++ K++ + + +E QS+ ++
Sbjct: 1228 NLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEA-------QVQELQSKCSDGER 1280
Query: 1475 EARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGKNVHELEKVR-- 1532
L+ ++ KL+N E L + + L ++++ L+ QL + + + E + +
Sbjct: 1281 ARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLN 1340
Query: 1533 -----KQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQ 1587
+QLE E+ LQ L+E + ++ E I ++ + K +++ A E +E+
Sbjct: 1341 VSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQ-DFASTVEALEE 1399
Query: 1588 AKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKS 1647
K+ Q+ +++L + + + +++ + K +++ +L+++ + L + ++ + +K+ +
Sbjct: 1400 GKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRK 1459
Query: 1648 LQSLLKD----TQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKL 1703
LL + + D+ RA + +E E + L LEE E+ ER+ K+
Sbjct: 1460 FDQLLAEEKNISSKYADERDRAEAEAREK----ETKALSLARALEEALEAKEELERTNKM 1515
Query: 1704 AEQELIETSERVQLLHSQNTSLINQKKKMESDLTQLQSEVEEAVQECRNAEE-KAKKAIT 1762
+ E+ + + L K+ +E+ + ++++++EE E + E+ K + +
Sbjct: 1516 LKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVN 1575
Query: 1763 DAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRL-DEAEQIALKGGKKQLQKLEARV 1821
A+ + + Q E ++ +++ + + + L DE +Q AL K+ KLE +
Sbjct: 1576 MQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKK--KLEGDL 1633
Query: 1822 RELEGELEAEQKRNAESVKGMRKSERRIKELTYQTEEDKKNLLRLQDLVDKLQLKVKAYK 1881
++LE + ++ K E++K +RK + ++K+ +Q E + R + + + KA
Sbjct: 1634 KDLELQADSAIKGREEAIKQLRKLQAQMKD--FQRELEDARASRDEIFATAKENEKKAKS 1691
Query: 1882 RQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQV--NKLRAKSRDIGAKQKMHDEE 1939
+A+ + Q + ++ + Q +L++ E ++A S N L+ + R + A+ +EE
Sbjct: 1692 LEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEE 1751
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 1406 bits (3640), Expect = 0.0
Identities = 771/1903 (40%), Positives = 1163/1903 (61%), Gaps = 26/1903 (1%)
Query: 38 FVPDDKEEFVKAKILSREGGKVIAE-TENGKTVTVKEDQVLQQNPPKFDKIEDMAMLTFL 96
+VP DK F A + G + I E ENGK V V +D + + NPPKF K+EDMA LT L
Sbjct: 33 WVPSDKSGFEPASLKEEVGEEAIVELVENGKKVKVNKDDIQKMNPPKFSKVEDMAELTCL 92
Query: 97 HEPAVLFNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNAEVVAAYRGKKRSEAPPHIFS 156
+E +VL NLKERY + +IYTYSGLFCV +NPYK LP+Y+ E+V Y+GKKR E PPHI++
Sbjct: 93 NEASVLHNLKERYYSGLIYTYSGLFCVVINPYKNLPIYSEEIVEMYKGKKRHEMPPHIYA 152
Query: 157 ISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFASIAAIGDRGKKDNANANKGT 216
I+D AY+ M+ DRE+QSIL TGESGAGKT NTK+VIQY A +A+ + KKD +G
Sbjct: 153 ITDTAYRSMMQDREDQSILCTGESGAGKTENTKKVIQYLAYVAS-SHKSKKD-----QGE 206
Query: 217 LEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLEKSRVIF 276
LE Q++QANP LEAFGNAKTV+NDNSSRFGKFIRI+F G + A+IETYLLEKSR I
Sbjct: 207 LERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVNGYIVGANIETYLLEKSRAIR 266
Query: 277 QLKAERNYHIFYQILSNKKPELLDMLLVTNNPYD-YAFVSQGEVSVASIDDSEELMATDS 335
Q K ER +HIFY +LS L LL+ PY+ Y F+S G V++ D + T
Sbjct: 267 QAKEERTFHIFYYLLSGAGEHLKTDLLL--EPYNKYRFLSNGHVTIPGQQDKDMFQETME 324
Query: 336 AFDVLGFTSEEKAGVYKLTGAIMHYGNMKFKQKQREEQAEPDGTEDADKSAYLMGLNSAD 395
A ++G EE+ G+ ++ ++ GN+ FK+++ +QA A K ++L+G+N D
Sbjct: 325 AMRIMGIPEEEQMGLLRVISGVLQLGNIVFKKERNTDQASMPDNTAAQKVSHLLGINVTD 384
Query: 396 LLKGLCHPRVKVGNEYVTKGQSVQQVYYSIGALAKAVYEKMFNWMVTRINATLE-TKQPR 454
+G+ PR+KVG +YV K Q+ +Q ++I ALAKA YE+MF W+V RIN L+ TK+
Sbjct: 385 FTRGILTPRIKVGRDYVQKAQTKEQADFAIEALAKATYERMFRWLVLRINKALDKTKRQG 444
Query: 455 QYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDF 514
FIG+LDIAGFEIFD NSFEQLCIN+TNEKLQQ FNH MF+LEQEEY++EGIEW FIDF
Sbjct: 445 ASFIGILDIAGFEIFDLNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDF 504
Query: 515 GMDLQACIDLIEKPMG---IMSILEEECMFPKATDMTFKAKLYDNHLGKSNNFQKPRNIK 571
G+DLQ CIDLIEKP G I+++L+EEC FPKATD +F K+ G FQKP+ +K
Sbjct: 505 GLDLQPCIDLIEKPAGPPGILALLDEECWFPKATDKSFVEKVMQEQ-GTHPKFQKPKQLK 563
Query: 572 GKQEAHFSLIHYAGTVDYNILGWLEKNKDPLNETVVALYQKSSLKLMATLFSSY------ 625
K A F +IHYAG VDY WL KN DPLN+ + L +SS K ++ L+
Sbjct: 564 DK--ADFCIIHYAGKVDYKADEWLMKNMDPLNDNIATLLHQSSDKFVSELWKDVDRIIGL 621
Query: 626 -ATADTGDSGKSKGGKKKGSSFQTVSALHRENLNKLMTNLRTTHPHFVRCIIPNERKAPG 684
A ++ K + F+TV L++E L KLM LR T+P+FVRCIIPN K G
Sbjct: 622 DQVAGMSETALPGAFKTRKGMFRTVGQLYKEQLAKLMATLRNTNPNFVRCIIPNHEKKAG 681
Query: 685 VMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRILNPVAIPEGQFIDSRKGT 744
+D LV+ QLRCNGVLEGIRICR+GFPNR+++ +FRQRY IL P +IP+G F+D ++
Sbjct: 682 KLDPHLVLDQLRCNGVLEGIRICRQGFPNRVVFQEFRQRYEILTPNSIPKG-FMDGKQAC 740
Query: 745 EKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLSRIITRMQAQARGQLMRIEFK 804
++ +L++D N Y+ G +KVFF+AG+L LEE RD +++ +I QA RG L R F
Sbjct: 741 VLMIKALELDSNLYRIGQSKVFFRAGVLAHLEEERDLKITDVIIGFQACCRGYLARKAFA 800
Query: 805 KIVERRDALLVIQWNIRAFMGVKNWPWMKLYFKIKPLLKSAETEKEMATMKEEFGRIKET 864
K ++ A+ V+Q N A++ ++NW W +L+ K+KPLL+ + E+EM +EE +++E
Sbjct: 801 KRQQQLTAMKVLQRNCAAYLKLRNWQWWRLFTKVKPLLQVSRQEEEMMAKEEELVKVREK 860
Query: 865 LEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLNDAEERCDQLIKNKIQLEAKVKEM 924
+E R E+E L+ EK LQ Q+QAE + +AEE +L K +LE ++
Sbjct: 861 QLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEELRARLTAKKQELEEICHDL 920
Query: 925 NERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEM 984
R+E+EEE L A+K+K++ EL++ +++ E K++ EK TE K+K L EE
Sbjct: 921 EARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQ 980
Query: 985 AGLDEIIAKLTKEKKALQEAHQQALDDLQVEEDKVNSLSKSKVKLEQQVDDLEGSLEQEK 1044
L++ KL KEKK L++ + +L EE+K SL+K K K E + DLE L +E+
Sbjct: 981 IILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREE 1040
Query: 1045 KVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQVLAL 1104
K R +LE+ +RKLEGD + I +L+ +L+ +L KKE ++ +++E+E
Sbjct: 1041 KQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKN 1100
Query: 1105 QLQKKLKENQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIE 1164
KK++E +++I EL+E+LE+ER +R K EK + DL ELE + LE+ +T+ Q E
Sbjct: 1101 MALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQE 1160
Query: 1165 MNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKS 1224
+ KRE E +++ LEE HEA +R+KH+ +V EL EQ++ +RVK LEK K
Sbjct: 1161 LRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQ 1220
Query: 1225 EFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQT 1284
+ E ++ + ++ +++ K + E + +E Q E +VK E +R + + KLQ
Sbjct: 1221 TLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQV 1280
Query: 1285 ENGELARQLEEKEALISQLTRGKLSYTQQMEDLKRQLEEEGKAKNALAHALQSARHDCDL 1344
E + L + ++ S+LT+ + Q++D + L+EE + K +L+ L+ + +
Sbjct: 1281 ELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNS 1340
Query: 1345 LREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEE 1404
REQ EEE EAK L++ ++ +++VA + K E D++ E EE K+KL + L+ +
Sbjct: 1341 FREQLEEEEEAKHNLEKQIATLHAQVADMKKKME-DSVGCLETAEEVKRKLQKDLEGLSQ 1399
Query: 1405 AVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEE 1464
E A LEKTK RLQ E++DL+VD++ +A L+KKQ+ FD++LAE K +
Sbjct: 1400 RHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAK 1459
Query: 1465 SQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGKN 1524
E + ++ EAR T+ L A EE++E +R NK + E+ DL + GK+
Sbjct: 1460 YAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKS 1519
Query: 1525 VHELEKVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEE 1584
VHELEK ++ LE + E+++ LEE E L+ E LR ++ +KA+ ER L +DE+
Sbjct: 1520 VHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQ 1579
Query: 1585 MEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLNEMEIQLSHANRMAAEAQKQ 1644
E+ K+ R V ++ L+ E + R+ + +KK+E DL ++E + AN+ EA KQ
Sbjct: 1580 SEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQ 1639
Query: 1645 VKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLA 1704
++ LQ+ +KD +LDD + +++ E++ ++AE+ +L+ + ER+++ A
Sbjct: 1640 LRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQA 1699
Query: 1705 EQELIETSERVQLLHSQNTSLINQKKKMESDLTQLQSEVEEAVQECRNAEEKAKKAITDA 1764
+QE E ++ + + + +K+++E+ + QL+ E+EE ++ KKA
Sbjct: 1700 QQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQI 1759
Query: 1765 AMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVREL 1824
+ +L E+ + E ++ +E+ K+L+ +L E E K + LEA++ +L
Sbjct: 1760 DQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQL 1819
Query: 1825 EGELEAEQKRNAESVKGMRKSERRIKELTYQTEEDKKNLLRLQDLVDKLQLKVKAYKRQA 1884
E +L+ E K + K +R++E+++K++ Q +++++N + +D DK ++K KRQ
Sbjct: 1820 EEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQL 1879
Query: 1885 EEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSR 1927
EEAEE+A + RK+Q EL++A E AD +V+ L+ K R
Sbjct: 1880 EEAEEEAQRANASRRKLQRELEDATETADAMNREVSSLKNKLR 1922
Score = 254 bits (648), Expect = 7e-67
Identities = 240/987 (24%), Positives = 449/987 (45%), Gaps = 113/987 (11%)
Query: 848 EKEMATMKEEFGRIKETLEK--SEARRKELEEKMV-------SLLQEKNDLQLQVQAEQD 898
E E +EE R K LEK +EA+ K+LEE+ + L +EK L+ ++
Sbjct: 947 ELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTT 1006
Query: 899 NLNDAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLE-------DECSE 951
NL + EE+ L K K + EA + ++ ERL EE+ EL +RKLE D+ +E
Sbjct: 1007 NLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAE 1066
Query: 952 LKKDIDDLELTLAKVEKE--------------KHATENKVKNLTEEMAGLDEIIAK---- 993
L+ I +L++ LAK E+E K+ K++ L +++ L E +
Sbjct: 1067 LQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERAS 1126
Query: 994 ----------LTKEKKALQEAHQQALDDLQVE-------EDKVNSLSKS----------- 1025
L +E +AL+ + LD + E +VN L K+
Sbjct: 1127 RNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQ 1186
Query: 1026 ----KVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEEK 1081
+ K Q V++L LEQ K+V+ +LE+AK+ LE + + L K E K
Sbjct: 1187 IQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHK 1246
Query: 1082 LKKKEFDINQQNSKIEDEQVLALQLQKKLKENQARIEELEEELEAERTARAKVEKLRSDL 1141
KK E + + K + + + +L K+ + Q ++ + L + +K+ K S L
Sbjct: 1247 RKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSAL 1306
Query: 1142 SRELEEISERLEEAGGAT--------SVQIEMNKKREA--EFQKMRRDLEEATLQHEATA 1191
+L++ E L+E V+ E N RE E ++ + +LE+ A
Sbjct: 1307 ESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQV 1366
Query: 1192 AALRKKHADSVA--ELGEQID-----NLQRVKQ----------KLEKEKSEFKLELDDVT 1234
A ++KK DSV E E++ +L+ + Q KLEK K+ + ELDD+
Sbjct: 1367 ADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLL 1426
Query: 1235 SNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQTENGELARQLE 1294
+++ ++ NLEK + + E + + + + + +T+ LAR LE
Sbjct: 1427 VDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALE 1486
Query: 1295 EKEALISQLTRGKLSYTQQMEDLKRQLEEEGKAKNALAHALQSARHDCDLLREQYEEETE 1354
E ++L R + +MEDL ++ GK+ + L + ++ + ++ Q EE +
Sbjct: 1487 EAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELED 1546
Query: 1355 AKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCS 1414
+ + + + ++E D R E+ EE KK+L +++++ E +E + S
Sbjct: 1547 ELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRS 1606
Query: 1415 SLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFD-------KILAEWKQKYEESQS 1467
+ +L+ +++DL ++ +N K+ R + L + + EE +
Sbjct: 1607 MAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILA 1666
Query: 1468 ELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGKNVHE 1527
+ + ++K+ +S+ E+ +L +E L E KR+ + ++E++D E GK
Sbjct: 1667 QAKENEKKLKSMEAEMIQL----QEELAAAERAKRQAQQERDELAD--EIANSSGKGALA 1720
Query: 1528 LEKVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEI--ERKLAEKDEEM 1585
LE+ R+ LE +L+ LEE + + E ++ +A L+ +QI ++ ER A+K+E
Sbjct: 1721 LEEKRR-LEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKNENA 1779
Query: 1586 -EQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLNEMEIQLSHANRMAAEAQKQ 1644
+Q +R ++ + LQ + E +++ +E + ++E QL + + A KQ
Sbjct: 1780 RQQLERQNKELKVKLQ---EMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAACKQ 1836
Query: 1645 VKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLA 1704
V+ + LKD +Q+DD R + K+ R L+ +LEE ++ SR+
Sbjct: 1837 VRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKL 1896
Query: 1705 EQELIETSERVQLLHSQNTSLINQKKK 1731
++EL + +E ++ + +SL N+ ++
Sbjct: 1897 QRELEDATETADAMNREVSSLKNKLRR 1923
Score = 195 bits (496), Expect = 3e-49
Identities = 206/904 (22%), Positives = 392/904 (43%), Gaps = 117/904 (12%)
Query: 1079 EEKLKKKEFDINQQNSKIEDEQVLALQLQKKLKENQARIEELEEELEAERTARAKVEKLR 1138
EE +K +E + +N E E + + + +KL +L+E+L+AE A+ E+LR
Sbjct: 852 EELVKVREKQLAAENRLTEMETLQSQLMAEKL--------QLQEQLQAETELCAEAEELR 903
Query: 1139 SDLS---RELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALR 1195
+ L+ +ELEEI LE R + EE QH A +
Sbjct: 904 ARLTAKKQELEEICHDLEA----------------------RVEEEEERCQH---LQAEK 938
Query: 1196 KKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKAN--LEKVSRT 1253
KK ++ EL EQ++ + +QKL+ EK + +L + EQII N L K +
Sbjct: 939 KKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEE--EQIILEDQNCKLAKEKKL 996
Query: 1254 LEDQANEYRVKLEEAQRSLNDFTTQRAKLQTENGELARQLEEKEALISQLTRGKLSYTQQ 1313
LED+ E FTT + + ++ LA+ + EA+I+
Sbjct: 997 LEDRIAE--------------FTTNLTEEEEKSKSLAKLKNKHEAMIT------------ 1030
Query: 1314 MEDLKRQLEEEGKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQW 1373
DL+ +L E K + L + D L +Q E AEL+ L+K E+
Sbjct: 1031 --DLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAA 1088
Query: 1374 RTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVD 1433
+ E +A Q+ L++ ++ L ++ + +E +E+ A + EK K L E+E L +
Sbjct: 1089 LARVEEEAAQKNMALKKIRE-LESQISELQEDLESERASRNKAEKQKRDLGEELEALKTE 1147
Query: 1434 VERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEES 1493
+E + + AA + + ++ + K+ EE E+ +E R K A EE
Sbjct: 1148 LEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQ------KHSQAVEEL 1201
Query: 1494 LEHLETFKRENKNLQEEISDLTEQLGEGGKNVHEL-------EKVRKQLEVEKLELQSAL 1546
E LE KR NL++ L + GE V L E RK++E + ELQ
Sbjct: 1202 AEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKF 1261
Query: 1547 EEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHQRVVDSLQTS---L 1603
E E K+ + Q+E + + L++ D + + ++ + LQ + L
Sbjct: 1262 NEGERVRTELADKVTKLQVELDNVTG----LLSQSDSKSSKLTKDFSALESQLQDTQELL 1317
Query: 1604 DAETRSRNEVLRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAV 1663
E R + + K++E + N QL +KQ+ +L + + D + +++D+V
Sbjct: 1318 QEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSV 1377
Query: 1664 RANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNT 1723
+ +E +++ L EE A ++ E+++ +QEL + +
Sbjct: 1378 GCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSAC 1437
Query: 1724 SLINQKKKMESDLTQLQSEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLER 1783
+L ++KK + L + ++ + +E AE +A++ T A +A L++ + A LER
Sbjct: 1438 NLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELER 1497
Query: 1784 MKKNMEQTIKDLQHRLDEAEQIA--LKGGKK----QLQKLEARVRELEGELEAE------ 1831
+ K ++DL D+ + L+ K+ Q+++++ ++ ELE EL+A
Sbjct: 1498 LNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLR 1557
Query: 1832 ----------------QKRNAESVKGMRKSERRIKELTYQTEEDKKNLLRLQDLVDKLQL 1875
Q R+ +S + ++ R+++E+ + E+++K KL++
Sbjct: 1558 LEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEM 1617
Query: 1876 KVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSRDIGAKQKM 1935
+K + + A + + + + RK+Q ++ + D + ++ A++++ K K
Sbjct: 1618 DLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKS 1677
Query: 1936 HDEE 1939
+ E
Sbjct: 1678 MEAE 1681
Score = 151 bits (381), Expect = 7e-36
Identities = 150/650 (23%), Positives = 298/650 (45%), Gaps = 59/650 (9%)
Query: 843 KSAETEKEMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLND 902
KS++ K+ + ++ + +E L++ ++ L K+ + EKN + Q++ E++ ++
Sbjct: 1295 KSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHN 1354
Query: 903 AEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAEL--------------TAKKRKLEDE 948
E++ L ++ K+++ LE EE+ +L A KLE
Sbjct: 1355 LEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKT 1414
Query: 949 CSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEK-KALQEAHQQ 1007
+ L++++DDL + L + E K K + +A I AK +E+ +A EA ++
Sbjct: 1415 KTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREK 1474
Query: 1008 ---------ALDDLQVEEDKVNSLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLE 1058
AL++ ++ ++ L+K + +++DL S + K +LE++KR LE
Sbjct: 1475 ETKALSLARALEEAMEQKAELERLNK---QFRTEMEDLMSSKDDVGKSVHELEKSKRALE 1531
Query: 1059 GDLKLTQESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQVLA---LQLQKKLKENQA 1115
++ + + +LE D+LQ E K + ++N Q K + E+ L Q ++K K+
Sbjct: 1532 QQVEEMKTQLEELE-DELQATEDAKLR-LEVNLQAMKAQFERDLQGRDEQSEEKKKQLVR 1589
Query: 1116 RIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQK 1175
++ E+E ELE ER R+ R L +L+++ ++ A I+ +K +A+ +
Sbjct: 1590 QVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKD 1649
Query: 1176 MRRDLEEATLQHEATAAALR------KKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLE 1229
R+L++ E A + K + +L E++ +R K++ ++E+ E E
Sbjct: 1650 CMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADE 1709
Query: 1230 LDDVTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQTENGEL 1289
+ + + ++ K LE LE++ E E+ L + ++A LQ +
Sbjct: 1710 IANSSGKGALALEEKRRLEARIAQLEEELEE-----EQGNTELINDRLKKANLQIDQINT 1764
Query: 1290 ARQLEEKEALISQLTRGKLSYTQQMEDLKRQLEE-EGKAKNALAHALQSARHDCDLLREQ 1348
LE A ++ R +L +Q ++LK +L+E EG K+ ++ + L EQ
Sbjct: 1765 DLNLERSHAQKNENARQQLE--RQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQ 1822
Query: 1349 YEEET---EAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAK---KKLAQRLQDA 1402
+ ET +A + R K +V +A Q ++ ++A K+L ++L++A
Sbjct: 1823 LDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEA 1882
Query: 1403 EEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFD 1452
EE + NA ++ +LQ E+ED + N ++L K R D
Sbjct: 1883 EEEAQRANA-------SRRKLQRELEDATETADAMNREVSSLKNKLRRGD 1925
Score = 93.2 bits (230), Expect = 2e-18
Identities = 88/327 (26%), Positives = 161/327 (49%), Gaps = 35/327 (10%)
Query: 1612 EVLRVKKKMEGDLNEM----EIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRAND 1667
+V R +++M E+ E QL+ NR+ ++++LQS L ++QL + ++A
Sbjct: 839 QVSRQEEEMMAKEEELVKVREKQLAAENRLT-----EMETLQSQLMAEKLQLQEQLQAET 893
Query: 1668 DLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLIN 1727
+L A E L A+ +EL + E ++ E+E ER Q L ++
Sbjct: 894 EL---CAEAEELRARLTAKKQELEEICHDLEA--RVEEEE-----ERCQHLQAE------ 937
Query: 1728 QKKKMESDLTQLQSEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQ----DTSAHLER 1783
KKKM+ ++ +L+ ++EE +E + + +K T+A + ++L++EQ D + L +
Sbjct: 938 -KKKMQQNIQELEEQLEE--EESARQKLQLEKVTTEAKL--KKLEEEQIILEDQNCKLAK 992
Query: 1784 MKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELEGELEAEQKRNAESVKGMR 1843
KK +E I + L E E+ + K K K EA + +LE L E+K+ E K R
Sbjct: 993 EKKLLEDRIAEFTTNLTEEEEKS-KSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRR 1051
Query: 1844 KSERRIKELTYQTEEDKKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQH 1903
K E +L+ Q E + + L+ + K + +++A + EE Q N L K R+++
Sbjct: 1052 KLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELES 1111
Query: 1904 ELDEAEERADIAESQVNKLRAKSRDIG 1930
++ E +E + + NK + RD+G
Sbjct: 1112 QISELQEDLESERASRNKAEKQKRDLG 1138
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 1403 bits (3632), Expect = 0.0
Identities = 774/1904 (40%), Positives = 1175/1904 (61%), Gaps = 25/1904 (1%)
Query: 38 FVPDDKEEFVKAKILSREGGKVIAE-TENGKTVTVKEDQVLQQNPPKFDKIEDMAMLTFL 96
++P ++ F A I G +V+ E ENGK V +D + + NPPKF K+EDMA LT L
Sbjct: 37 WIPSERHGFEAASIKEERGDEVMVELAENGKKAMVNKDDIQKMNPPKFSKVEDMAELTCL 96
Query: 97 HEPAVLFNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNAEVVAAYRGKKRSEAPPHIFS 156
+E +VL NLK+RY + +IYTYSGLFCV +NPYK LP+Y+ ++ YRGKKR E PPHI++
Sbjct: 97 NEASVLHNLKDRYYSGLIYTYSGLFCVVINPYKNLPIYSENIIEMYRGKKRHEMPPHIYA 156
Query: 157 ISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFASIAAIGDRGKKDNANANKGT 216
IS++AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY A +A+ +G+KD+ G
Sbjct: 157 ISESAYRCMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVAS-SHKGRKDHNIP--GE 213
Query: 217 LEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLEKSRVIF 276
LE Q++QANP LE+FGNAKTV+NDNSSRFGKFIRI+F TG + A+IETYLLEKSR +
Sbjct: 214 LERQLLQANPILESFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAVR 273
Query: 277 QLKAERNYHIFYQILSNKKPELL-DMLLVTNNPYDYAFVSQGEVSVASIDDSEELMATDS 335
Q K ER +HIFYQ+LS L D+LL N +Y F+S G + + D + T
Sbjct: 274 QAKDERTFHIFYQLLSGAGEHLKSDLLLEGFN--NYRFLSNGYIPIPGQQDKDNFQETME 331
Query: 336 AFDVLGFTSEEKAGVYKLTGAIMHYGNMKFKQKQREEQAEPDGTEDADKSAYLMGLNSAD 395
A ++GF+ EE + K+ +++ +GN+ FK+++ +QA A K +L+G+N +
Sbjct: 332 AMHIMGFSHEEILSMLKVVSSVLQFGNISFKKERNTDQASMPENTVAQKLCHLLGMNVME 391
Query: 396 LLKGLCHPRVKVGNEYVTKGQSVQQVYYSIGALAKAVYEKMFNWMVTRINATLE-TKQPR 454
+ + PR+KVG +YV K Q+ +Q +++ ALAKA YE++F W+V RIN L+ TK+
Sbjct: 392 FTRAILTPRIKVGRDYVQKAQTKEQADFAVEALAKATYERLFRWLVHRINKALDRTKRQG 451
Query: 455 QYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDF 514
FIG+LDIAGFEIF+ NSFEQLCIN+TNEKLQQ FNH MF+LEQEEY++EGIEW FIDF
Sbjct: 452 ASFIGILDIAGFEIFELNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDF 511
Query: 515 GMDLQACIDLIEKPM---GIMSILEEECMFPKATDMTFKAKLYDNHLGKSNNFQKPRNIK 571
G+DLQ CIDLIE+P G++++L+EEC FPKATD TF KL G + FQKPR +K
Sbjct: 512 GLDLQPCIDLIERPANPPGVLALLDEECWFPKATDKTFVEKLVQEQ-GSHSKFQKPRQLK 570
Query: 572 GKQEAHFSLIHYAGTVDYNILGWLEKNKDPLNETVVALYQKSSLKLMATLFSSY------ 625
K A F +IHYAG VDY WL KN DPLN+ V L +SS + +A L+
Sbjct: 571 DK--ADFCIIHYAGKVDYKADEWLMKNMDPLNDNVATLLHQSSDRFVAELWKDVDRIVGL 628
Query: 626 --ATADTGDSGKSKGGKKKGSSFQTVSALHRENLNKLMTNLRTTHPHFVRCIIPNERKAP 683
T T + S KKG F+TV L++E+L KLM LR T+P+FVRCIIPN K
Sbjct: 629 DQVTGMTETAFGSAYKTKKGM-FRTVGQLYKESLTKLMATLRNTNPNFVRCIIPNHEKRA 687
Query: 684 GVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRILNPVAIPEGQFIDSRKG 743
G +D LV+ QLRCNGVLEGIRICR+GFPNRI++ +FRQRY IL P AIP+G F+D ++
Sbjct: 688 GKLDPHLVLDQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILTPNAIPKG-FMDGKQA 746
Query: 744 TEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLSRIITRMQAQARGQLMRIEF 803
E+++ +L++D N Y+ G +K+FF+AG+L LEE RD +++ II QA RG L R F
Sbjct: 747 CERMIRALELDPNLYRIGQSKIFFRAGVLAHLEEERDLKITDIIIFFQAVCRGYLARKAF 806
Query: 804 KKIVERRDALLVIQWNIRAFMGVKNWPWMKLYFKIKPLLKSAETEKEMATMKEEFGRIKE 863
K ++ AL V+Q N A++ +++W W +++ K+KPLL+ E+E+ EE ++KE
Sbjct: 807 AKKQQQLSALKVLQRNCAAYLKLRHWQWWRVFTKVKPLLQVTRQEEELQAKDEELLKVKE 866
Query: 864 TLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLNDAEERCDQLIKNKIQLEAKVKE 923
K E +E+E K LL+EKN L Q+QAE + +AEE +L K +LE + +
Sbjct: 867 KQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMRARLAAKKQELEEILHD 926
Query: 924 MNERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEE 983
+ R+E+EEE N L +K+K++ +L++ +D+ E K++ EK E K+K + EE
Sbjct: 927 LESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEE 986
Query: 984 MAGLDEIIAKLTKEKKALQEAHQQALDDLQVEEDKVNSLSKSKVKLEQQVDDLEGSLEQE 1043
+ L++ +K KEKK +++ + L EE+K +L+K + K E + DLE L++E
Sbjct: 987 ILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKE 1046
Query: 1044 KKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQVLA 1103
+K R +LE+AKRKL+G+ Q+ I +L+ +L+ +L KKE ++ ++ +DE +
Sbjct: 1047 EKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGALARGDDETLHK 1106
Query: 1104 LQLQKKLKENQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQI 1163
K ++E QA+I EL+E+ E+E+ +R K EK + DLS ELE + LE+ T+ Q
Sbjct: 1107 NNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQ 1166
Query: 1164 EMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEK 1223
E+ KRE E ++++ LEE T HEA +R++HA ++ EL EQ++ +R K LEK K
Sbjct: 1167 ELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNK 1226
Query: 1224 SEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQ 1283
+ + ++ ++ + + KA E + L+ Q E K+ E R + + +KLQ
Sbjct: 1227 QGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQ 1286
Query: 1284 TENGELARQLEEKEALISQLTRGKLSYTQQMEDLKRQLEEEGKAKNALAHALQSARHDCD 1343
E ++ LEE E + + S Q++D + L+EE + K L+ ++ + +
Sbjct: 1287 NELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKN 1346
Query: 1344 LLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAE 1403
L+EQ EEE EA+ L++ + S++A + K + D + E LEEAKKKL + +
Sbjct: 1347 SLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDD-LGTIESLEEAKKKLLKDAEALS 1405
Query: 1404 EAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYE 1463
+ +E LEKTK+RLQ E++DL VD++ A+ L+KKQ+ FD++LAE K
Sbjct: 1406 QRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISA 1465
Query: 1464 ESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGK 1523
E + ++ EAR T+ L A EE+LE E F+R+NK L+ ++ DL + GK
Sbjct: 1466 RYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGK 1525
Query: 1524 NVHELEKVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDE 1583
NVHELEK ++ LE + E+++ LEE E L+ E LR ++ +KA+ ER L +DE
Sbjct: 1526 NVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDE 1585
Query: 1584 EMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLNEMEIQLSHANRMAAEAQK 1643
+ E+ KR + V L+ L+ E + R + KKKME DL ++E Q+ AN+ E K
Sbjct: 1586 QNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIK 1645
Query: 1644 QVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKL 1703
Q++ LQ+ +KD Q +L++A + D++ E++ L+AE+ +L+ + +ER+R+
Sbjct: 1646 QLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRH 1705
Query: 1704 AEQELIETSERVQLLHSQNTSLINQKKKMESDLTQLQSEVEEAVQECRNAEEKAKKAITD 1763
AEQE E ++ + S ++L+++K+++E+ + QL+ E+EE ++ +K
Sbjct: 1706 AEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQ 1765
Query: 1764 AAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRE 1823
+ EL E+ + + ++ +E+ K+L+ +L E E K + LEA++ +
Sbjct: 1766 VDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQ 1825
Query: 1824 LEGELEAEQKRNAESVKGMRKSERRIKELTYQTEEDKKNLLRLQDLVDKLQLKVKAYKRQ 1883
LE +LE E K A + K +R++E+++KE+ Q E+++++ + ++ ++K ++K KRQ
Sbjct: 1826 LEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQ 1885
Query: 1884 AEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSR 1927
EEAEE+A + RK+Q ELD+A E + +V+ L+ + R
Sbjct: 1886 LEEAEEEATRANASRRKLQRELDDATEANEGLSREVSTLKNRLR 1929
Score = 246 bits (628), Expect = 2e-64
Identities = 223/981 (22%), Positives = 446/981 (45%), Gaps = 115/981 (11%)
Query: 855 KEEFGRIKETLEK--SEARRKELEEKMVSL-------LQEKNDLQLQVQAEQDNLNDAEE 905
+EE R K LEK +EA+ K++EE+++ L ++EK ++ ++ L + EE
Sbjct: 961 EEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEE 1020
Query: 906 RCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLE-------DECSELKKDIDD 958
+ L K + + E + ++ ERL+ EE+ EL KRKL+ D+ +EL+ ID+
Sbjct: 1021 KAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDE 1080
Query: 959 LELTLAKVEKE--------------KHATENKVKNLTEEMAGLDEIIA-------KLTKE 997
L+L LAK E+E K+ V+ L ++A L E K K+
Sbjct: 1081 LKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQ 1140
Query: 998 KKALQEAHQQALDDLQVEEDKVNSLSKSKVKLEQQVDDLEGSLEQE-------------- 1043
K+ L E + +L+ D + + + K EQ+V +L+ +LE+E
Sbjct: 1141 KRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQR 1200
Query: 1044 ---------------KKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFD 1088
K+ + +LE+ K+ LE D K + L+ K + E K KK +
Sbjct: 1201 HATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQ 1260
Query: 1089 INQQNSKIEDEQVLALQLQKKLKENQARIEELEEELEAERTARAKVEKLRSDLSRELEEI 1148
+ + ++K+ + L ++L +K + Q ++ + LE K K + L +L++
Sbjct: 1261 VQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDT 1320
Query: 1149 SERLEEAGGAT---SVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAEL 1205
E L+E S +I ++ + Q+ + + EEA E AL+ + AD+ ++
Sbjct: 1321 QELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKV 1380
Query: 1206 GEQIDNLQRVKQ------------------------KLEKEKSEFKLELDDVTSNMEQII 1241
+ + ++ +++ KLEK K+ + ELDD+T +++
Sbjct: 1381 DDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQR 1440
Query: 1242 KAKANLEKVSRTLEDQ-ANEYRVKLEEAQRSLNDFTTQRAKLQTENGELARQLEEKEALI 1300
+ +NLEK + + A E + A+ R K +T+ LAR LEE
Sbjct: 1441 QVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREK-ETKALSLARALEEALEAK 1499
Query: 1301 SQLTRGKLSYTQQMEDLKRQLEEEGKAKNALAHALQSARHDCDLLREQYEEETEAKAELQ 1360
+ R MEDL ++ GK + L + ++ + +R Q EE + +
Sbjct: 1500 EEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATE 1559
Query: 1361 RVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTK 1420
+ + + ++E D R E+ EE K+ L +++++ E +E + + +K
Sbjct: 1560 DAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASK 1619
Query: 1421 HRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQS-------ELESSQ 1473
+++ +++DL +E +N A + K+ R + +++++ EE+++ + + S+
Sbjct: 1620 KKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESE 1679
Query: 1474 KEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGKNVHELEKVRK 1533
K+ +SL E+ +L+ E L + +R ++ ++E +L +++ L ++
Sbjct: 1680 KKLKSLEAEILQLQ-------EELASSERARRHAEQERDELADEITNSASGKSALLDEKR 1732
Query: 1534 QLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEI--ERKLAEK-DEEMEQAKR 1590
+LE +L+ LEE ++++E + + L+ + + AE+ ER A+K D +Q +R
Sbjct: 1733 RLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLER 1792
Query: 1591 NHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQS 1650
++ + LQ + E +++ +E + ++E QL + A A K V+ +
Sbjct: 1793 QNKELKAKLQ---ELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEK 1849
Query: 1651 LLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIE 1710
LK+ +Q++D R D KE + R L+ +LEE + SR+ ++EL +
Sbjct: 1850 KLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQRELDD 1909
Query: 1711 TSERVQLLHSQNTSLINQKKK 1731
+E + L + ++L N+ ++
Sbjct: 1910 ATEANEGLSREVSTLKNRLRR 1930
Score = 241 bits (616), Expect = 4e-63
Identities = 207/950 (21%), Positives = 437/950 (46%), Gaps = 49/950 (5%)
Query: 995 TKEKKALQEAHQQALDDLQVEEDKVNSLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAK 1054
TK K LQ Q+ ++LQ +++++ +K++++ +EG LE+ ++ L K
Sbjct: 839 TKVKPLLQVTRQE--EELQAKDEEL-------LKVKEKQTKVEGELEEMERKHQQLLEEK 889
Query: 1055 RKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQVLALQLQKKLKENQ 1114
L L+ E + E + +L K ++ E ++ S++E+E+ LQ + K+ Q
Sbjct: 890 NILAEQLQAETELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQ 949
Query: 1115 ARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQ 1174
A I++LEE+L+ E AR K++ LE+++ EA+ +
Sbjct: 950 AHIQDLEEQLDEEEGARQKLQ---------LEKVTA-------------------EAKIK 981
Query: 1175 KMRRDLEEATLQHEATAAALRKKHA--DSVAELGEQIDNLQRVKQKLEKEKSEFKLELDD 1232
KM EE L + + +++K D +AE Q+ + + L K +++ ++ + D
Sbjct: 982 KME---EEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISD 1038
Query: 1233 VTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQTE-NGELAR 1291
+ +++ K + LEK R L+ + + + ++ E Q +++ Q AK + E G LAR
Sbjct: 1039 LEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGALAR 1098
Query: 1292 QLEEKEALISQLTRGKLSYTQQMEDLKRQLEEEGKAKNALAHALQSARHDCDLLREQYEE 1351
+E + L + Q+ +L+ E E ++N + + + L+ + E+
Sbjct: 1099 GDDETLHKNNALKVVR-ELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELED 1157
Query: 1352 ETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNA 1411
+ A Q + +K EVA+ + E + ++++ +++ A L++ E +E
Sbjct: 1158 TLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKR 1217
Query: 1412 KCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELES 1471
++LEK K L+ + ++L +V+ A + K++ D + E K E
Sbjct: 1218 FKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVE 1277
Query: 1472 SQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGKNVHELEKV 1531
++A L EL + EE+ + F ++ +L+ ++ D E L E + L
Sbjct: 1278 LAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSR 1337
Query: 1532 RKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRN 1591
+QLE EK LQ EE E + ++ E ++L Q + K +++ L E +E+AK+
Sbjct: 1338 IRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTI-ESLEEAKKK 1396
Query: 1592 HQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSL 1651
+ ++L L+ + + +++ + K +++ +L+++ + L H ++A+ +K+ K L
Sbjct: 1397 LLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQL 1456
Query: 1652 LKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIET 1711
L + + D + E + L LEE E+ ER K ++ +
Sbjct: 1457 LAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDL 1516
Query: 1712 SERVQLLHSQNTSLINQKKKMESDLTQLQSEVEEAVQECRNAEE-KAKKAITDAAMMAEE 1770
+ L K+ +E + ++++++EE E + E+ K + + AM A+
Sbjct: 1517 MSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQF 1576
Query: 1771 LKKEQDTSAHLERMKKNMEQTIKDLQHRL-DEAEQIALKGGKKQLQKLEARVRELEGELE 1829
+ Q E K+ + + +++L+ L DE +Q AL K+ K+E +++LE ++E
Sbjct: 1577 ERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKK--KMEIDLKDLEAQIE 1634
Query: 1830 AEQKRNAESVKGMRKSERRIKELTYQTEEDKKNLLRLQDLVDKLQLKVKAYKRQAEEAEE 1889
A K E +K +RK + ++K+ + EE + + + + + K+K+ + + + +E
Sbjct: 1635 AANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQE 1694
Query: 1890 QANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSRDIGAKQKMHDEE 1939
+ ++ R + E DE + + S + L + R + A+ +EE
Sbjct: 1695 ELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEE 1744
>gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens]
Length = 2003
Score = 1295 bits (3351), Expect = 0.0
Identities = 726/1911 (37%), Positives = 1147/1911 (60%), Gaps = 34/1911 (1%)
Query: 38 FVPDDKEEFVKAKILSREGGKVIAETE---NGKTVTVKEDQVLQQNPPKFDKIEDMAMLT 94
+VP + F A + R+ G+ AE E +G+ + + DQ+ + NPPKF K EDMA LT
Sbjct: 57 WVPSELHGFEAAAL--RDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMAELT 114
Query: 95 FLHEPAVLFNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNAEVVAAYRGKKRSEAPPHI 154
L+E +VL NL+ERY + +IYTYSGLFCV +NPYK LP+Y +V YRGKKR E PPH+
Sbjct: 115 CLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVPPHV 174
Query: 155 FSISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFASIAAIGDRGKKDN----- 209
+++++ AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY A +A+ +G+K+
Sbjct: 175 YAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVAS-SPKGRKEPGVPAS 233
Query: 210 -ANANKGTLEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYL 268
+ + G LE Q++QANP LEAFGNAKTV+NDNSSRFGKFIRI+F G + A+IETYL
Sbjct: 234 VSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYL 293
Query: 269 LEKSRVIFQLKAERNYHIFYQILSNKKPELLDMLLVTNNPYDYAFVSQGEVSVASIDDSE 328
LEKSR I Q K E ++HIFYQ+L +L LL+ + Y F++ G S + E
Sbjct: 294 LEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSH-YRFLTNGPSSSPG-QERE 351
Query: 329 ELMATDSAFDVLGFTSEEKAGVYKLTGAIMHYGNMKFKQKQREEQAEPDGTEDADKSAYL 388
T + VLGF+ EE + ++ A++ +GN+ K+++ +QA A K L
Sbjct: 352 LFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRL 411
Query: 389 MGLNSADLLKGLCHPRVKVGNEYVTKGQSVQQVYYSIGALAKAVYEKMFNWMVTRINATL 448
+GL D + L PR+KVG +YV K Q+ +Q +++ ALAKA YE++F W+V R+N L
Sbjct: 412 LGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRAL 471
Query: 449 ETKQPRQ--YFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEG 506
+ + PRQ F+G+LDIAGFEIF NSFEQLCIN+TNEKLQQ FNH MFVLEQEEY++EG
Sbjct: 472 D-RSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREG 530
Query: 507 IEWTFIDFGMDLQACIDLIEKPM---GIMSILEEECMFPKATDMTFKAKLYDNHLGKSNN 563
I WTF+DFG+DLQ CIDLIE+P G++++L+EEC FPKATD +F K+ G
Sbjct: 531 IPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQ-GGHPK 589
Query: 564 FQKPRNIKGKQEAHFSLIHYAGTVDYNILGWLEKNKDPLNETVVALYQKSSLKLMATLFS 623
FQ+PR+++ +A FS++HYAG VDY WL KN DPLN+ V AL +S+ +L A ++
Sbjct: 590 FQRPRHLR--DQADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWK 647
Query: 624 SYA-------TADTGDSGKSKGGKKKGSSFQTVSALHRENLNKLMTNLRTTHPHFVRCII 676
+ GD GG+ + F+TV L++E+L++LM L T+P FVRCI+
Sbjct: 648 DVEGIVGLEQVSSLGDG--PPGGRPRRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCIV 705
Query: 677 PNERKAPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRILNPVAIPEGQ 736
PN K G ++ LV+ QLRCNGVLEGIRICR+GFPNRIL+ +FRQRY IL P AIP+G
Sbjct: 706 PNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPKG- 764
Query: 737 FIDSRKGTEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLSRIITRMQAQARG 796
F+D ++ EK++ +L++D N Y+ G +K+FF+AG+L LEE RD +++ II QA ARG
Sbjct: 765 FMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARG 824
Query: 797 QLMRIEFKKIVERRDALLVIQWNIRAFMGVKNWPWMKLYFKIKPLLKSAETEKEMATMKE 856
L R F+K +++ AL V+Q N A++ +++W W +L+ K+KPLL+ ++ + +
Sbjct: 825 YLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQ 884
Query: 857 EFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLNDAEERCDQLIKNKIQ 916
E +++E ++S EL+ ++ L +E+ L Q++AE + +AEE +L K +
Sbjct: 885 ELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQE 944
Query: 917 LEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENK 976
LE V E+ R+ +EEE + ++ +K++L+ EL+ ++ E K++ EK TE K
Sbjct: 945 LELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAK 1004
Query: 977 VKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQVEEDKVNSLSKSKVKLEQQVDDL 1036
+K E++ L++ +KL+KE+K L++ + EE+KV SL+K ++K E + D+
Sbjct: 1005 MKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADM 1064
Query: 1037 EGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDINQQNSKI 1096
E L +E+K R +LE+ KR+L+G+ QE +++ + +L +L +KE ++ ++
Sbjct: 1065 EDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARA 1124
Query: 1097 EDEQVLALQLQKKLKENQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAG 1156
EDE QL K L+E QA + E +E+LE+ER AR K EK R DL ELE + LE+
Sbjct: 1125 EDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTL 1184
Query: 1157 GATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVK 1216
+T+ Q E+ KRE E ++++ LEE T HEA LR++H ++ EL EQ++ +R K
Sbjct: 1185 DSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGK 1244
Query: 1217 QKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRSLNDFT 1276
EK + + E+ ++ + + + A+ E+ R LE Q E + + + +R+ +
Sbjct: 1245 GAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAA 1304
Query: 1277 TQRAKLQTENGELARQLEEKEALISQLTRGKLSYTQQMEDLKRQLEEEGKAKNALAHALQ 1336
+ + Q E ++ L E E+ +L++ S Q+ D + L+EE +AK AL ++
Sbjct: 1305 EKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVR 1364
Query: 1337 SARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLA 1396
+ + LREQ EEE A+ R L A +++++WR + E +A E EEA+++ A
Sbjct: 1365 AMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEA-GALEAGEEARRRAA 1423
Query: 1397 QRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILA 1456
+ + + + LE+ + RLQ E++D +D+E+ + L+KKQR FD++LA
Sbjct: 1424 REAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLA 1483
Query: 1457 EWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTE 1516
E K + E E ++ E R L A EE E E +R+N+ L+ E+ L
Sbjct: 1484 EEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLS 1543
Query: 1517 QLGEGGKNVHELEKVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIER 1576
+ GK+VHELE+ + E +L++ + E E L E LR ++ +K + ER
Sbjct: 1544 SKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHER 1603
Query: 1577 KLAEKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLNEMEIQLSHANR 1636
L +DE E+ +R + + + D E + R + +KK+EG+L E++ Q++ A +
Sbjct: 1604 DLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQ 1663
Query: 1637 MAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQ 1696
EA KQ++ +Q+ +K+ ++++ + +++ E+R L+AE+ L+ +
Sbjct: 1664 GKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAA 1723
Query: 1697 TERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMESDLTQLQSEVEEAVQECRNAEEK 1756
++R+R+ A+Q+ E ++ V + +++ +K+++E L QL+ E+EE ++
Sbjct: 1724 SDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDR 1783
Query: 1757 AKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQK 1816
+K + + EL E+ SA E ++ +E+ I++L+ RL E + A K +
Sbjct: 1784 YRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAA 1843
Query: 1817 LEARVRELEGELEAEQKRNAESVKGMRKSERRIKELTYQTEEDKKNLLRLQDLVDKLQLK 1876
LE+++ + E +LE E + S K +R++E+R+KE+ Q EE+++ +L+D ++K L+
Sbjct: 1844 LESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLR 1903
Query: 1877 VKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSR 1927
VK KRQ EEAEE+A+ + R++Q EL++ E A+ +V LR + R
Sbjct: 1904 VKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLR 1954
Score = 236 bits (601), Expect = 2e-61
Identities = 217/956 (22%), Positives = 432/956 (45%), Gaps = 61/956 (6%)
Query: 837 KIKPLLKSAETEKEMATMKEEFGRIKETLEKSEAR----RKELEEKMVSLLQEKNDLQLQ 892
K++ ++ + E KEE GR + LEK + R EL+E+MV Q +L+ Q
Sbjct: 1052 KLRLKYEATIADMEDRLRKEEKGR--QELEKLKRRLDGESSELQEQMVEQQQRAEELRAQ 1109
Query: 893 VQAEQDNLNDAEERCD-------QLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKL 945
+ +++ L A R + QL+K+ + +A + E E LE E + ++R L
Sbjct: 1110 LGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDL 1169
Query: 946 EDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAH 1005
+E L+ +++D TL ++ + + +TE L+E + L++ H
Sbjct: 1170 GEELEALRGELED---TLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRH 1226
Query: 1006 QQALDDL--QVEEDK--VNSLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDL 1061
QAL +L Q+E+ + + K+++ LE +V +L L + R + E+ +R+LE L
Sbjct: 1227 GQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQL 1286
Query: 1062 KLTQESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQVLALQLQKKLKENQARIEELE 1121
+ Q D E + + EKL++ + ++ + + + + ++L K+L +A++ + +
Sbjct: 1287 QEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQ 1346
Query: 1122 EELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLE 1181
E L+ E A+ + + E + E+LEE A + +A+ + RR E
Sbjct: 1347 ELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQE 1406
Query: 1182 EATLQHEATAAALRKKHADS------VAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTS 1235
E EA A R+ ++ +AE E +D L+R +++L++E LDD T
Sbjct: 1407 EEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQE-------LDDATM 1459
Query: 1236 NMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQTENGELARQLEE 1295
++EQ + + LEK R + E + + A + + + L R LEE
Sbjct: 1460 DLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEE 1519
Query: 1296 KEALISQLTRGKLSYTQQMEDLKRQLEEEGKAKNALAHALQSARHDCDLLREQYEEETEA 1355
++ +L R + ++E L ++ GK+ + L A + A + LR Q E +
Sbjct: 1520 EQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDE 1579
Query: 1356 KAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSS 1415
+ + V +T++E D R E EE +++LA++L+DAE + + +
Sbjct: 1580 LTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTL 1639
Query: 1416 LEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELES---- 1471
+ +L+ E+E+L + + K+ R + E ++ EE+++ E
Sbjct: 1640 AVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQ 1699
Query: 1472 ---SQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGKNVHEL 1528
S+K + L E+ +L+ E L R + Q++ ++ +++ G + +
Sbjct: 1700 NRESEKRLKGLEAEVLRLQ-------EELAASDRARRQAQQDRDEMADEVANGNLSKAAI 1752
Query: 1529 EKVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEI--ERKLAEKDEEME 1586
+ ++QLE +L+ LEE +++ E + + L+ + E+ ER + K E
Sbjct: 1753 LEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAK---AE 1809
Query: 1587 QAKRNHQRVVDSLQTSL---DAETRSRNEVLRVKKKMEGDLNEMEIQLSHANRMAAEAQK 1643
++ +R + L+ L DA R+R+++ +E L + E QL R + K
Sbjct: 1810 SGRQQLERQIQELRGRLGEEDAGARARHKMTIAA--LESKLAQAEEQLEQETRERILSGK 1867
Query: 1644 QVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKL 1703
V+ + LK+ +Q+++ R D L++ + R L+ +LEE + + R+
Sbjct: 1868 LVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRR 1927
Query: 1704 AEQELIETSERVQLLHSQNTSLINQKKKMESDLT----QLQSEVEEAVQECRNAEE 1755
++EL + +E + ++ + T+L N+ ++ T + +EE V AEE
Sbjct: 1928 LQRELEDVTESAESMNREVTTLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEEAEE 1983
Score = 71.2 bits (173), Expect = 9e-12
Identities = 71/306 (23%), Positives = 140/306 (45%), Gaps = 25/306 (8%)
Query: 1630 QLSHANRMAAEAQKQVKSLQ---SLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAE 1686
+L + ++ ++V LQ + L++ + +L + +RA +L A E L A
Sbjct: 885 ELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAEL---CAEAEETRGRLAAR 941
Query: 1687 LEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMESDLTQLQSEVEEA 1746
+EL VV + E ++ E+E E S ++Q +KK+++ + +L++ +E
Sbjct: 942 KQELELVVSELEA--RVGEEE--ECSRQMQ----------TEKKRLQQHIQELEAHLE-- 985
Query: 1747 VQECRNAEEKAKKAITDAAM--MAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQ 1804
+E + + +K T+A M E+L +D ++ L + +K +E + + + E E+
Sbjct: 986 AEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEE 1045
Query: 1805 IALKGGKKQLQKLEARVRELEGELEAEQKRNAESVKGMRKSERRIKELTYQTEEDKKNLL 1864
+K K K EA + ++E L E+K E K R+ + EL Q E ++
Sbjct: 1046 -KVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAE 1104
Query: 1865 RLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRA 1924
L+ + + + +++A +AE+ L R+ Q L EA+E + K
Sbjct: 1105 ELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEK 1164
Query: 1925 KSRDIG 1930
+ RD+G
Sbjct: 1165 QRRDLG 1170
>gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens]
Length = 1995
Score = 1295 bits (3351), Expect = 0.0
Identities = 726/1905 (38%), Positives = 1145/1905 (60%), Gaps = 30/1905 (1%)
Query: 38 FVPDDKEEFVKAKILSREGGKVIAETE---NGKTVTVKEDQVLQQNPPKFDKIEDMAMLT 94
+VP + F A + R+ G+ AE E +G+ + + DQ+ + NPPKF K EDMA LT
Sbjct: 57 WVPSELHGFEAAAL--RDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMAELT 114
Query: 95 FLHEPAVLFNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNAEVVAAYRGKKRSEAPPHI 154
L+E +VL NL+ERY + +IYTYSGLFCV +NPYK LP+Y +V YRGKKR E PPH+
Sbjct: 115 CLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVPPHV 174
Query: 155 FSISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFASIAAIGDRGKKDNANANK 214
+++++ AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY A +A+ +G+K+
Sbjct: 175 YAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVAS-SPKGRKEPGVP-- 231
Query: 215 GTLEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLEKSRV 274
G LE Q++QANP LEAFGNAKTV+NDNSSRFGKFIRI+F G + A+IETYLLEKSR
Sbjct: 232 GELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLLEKSRA 291
Query: 275 IFQLKAERNYHIFYQILSNKKPELLDMLLVTNNPYDYAFVSQGEVSVASIDDSEELMATD 334
I Q K E ++HIFYQ+L +L LL+ + Y F++ G S + E T
Sbjct: 292 IRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSH-YRFLTNGPSSSPG-QERELFQETL 349
Query: 335 SAFDVLGFTSEEKAGVYKLTGAIMHYGNMKFKQKQREEQAEPDGTEDADKSAYLMGLNSA 394
+ VLGF+ EE + ++ A++ +GN+ K+++ +QA A K L+GL
Sbjct: 350 ESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRLLGLGVT 409
Query: 395 DLLKGLCHPRVKVGNEYVTKGQSVQQVYYSIGALAKAVYEKMFNWMVTRINATLETKQPR 454
D + L PR+KVG +YV K Q+ +Q +++ ALAKA YE++F W+V R+N L+ + PR
Sbjct: 410 DFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALD-RSPR 468
Query: 455 Q--YFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFI 512
Q F+G+LDIAGFEIF NSFEQLCIN+TNEKLQQ FNH MFVLEQEEY++EGI WTF+
Sbjct: 469 QGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFL 528
Query: 513 DFGMDLQACIDLIEKPM---GIMSILEEECMFPKATDMTFKAKLYDNHLGKSNNFQKPRN 569
DFG+DLQ CIDLIE+P G++++L+EEC FPKATD +F K+ G FQ+PR+
Sbjct: 529 DFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQ-GGHPKFQRPRH 587
Query: 570 IKGKQEAHFSLIHYAGTVDYNILGWLEKNKDPLNETVVALYQKSSLKLMATLFSSYA--- 626
++ +A FS++HYAG VDY WL KN DPLN+ V AL +S+ +L A ++
Sbjct: 588 LR--DQADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKDVEGIV 645
Query: 627 ----TADTGDSGKSKGGKKKGSSFQTVSALHRENLNKLMTNLRTTHPHFVRCIIPNERKA 682
+ GD GG+ + F+TV L++E+L++LM L T+P FVRCI+PN K
Sbjct: 646 GLEQVSSLGDG--PPGGRPRRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKR 703
Query: 683 PGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRILNPVAIPEGQFIDSRK 742
G ++ LV+ QLRCNGVLEGIRICR+GFPNRIL+ +FRQRY IL P AIP+G F+D ++
Sbjct: 704 AGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPKG-FMDGKQ 762
Query: 743 GTEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLSRIITRMQAQARGQLMRIE 802
EK++ +L++D N Y+ G +K+FF+AG+L LEE RD +++ II QA ARG L R
Sbjct: 763 ACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRA 822
Query: 803 FKKIVERRDALLVIQWNIRAFMGVKNWPWMKLYFKIKPLLKSAETEKEMATMKEEFGRIK 862
F+K +++ AL V+Q N A++ +++W W +L+ K+KPLL+ ++ + +E +++
Sbjct: 823 FQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQELQKVQ 882
Query: 863 ETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLNDAEERCDQLIKNKIQLEAKVK 922
E ++S EL+ ++ L +E+ L Q++AE + +AEE +L K +LE V
Sbjct: 883 ELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVS 942
Query: 923 EMNERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTE 982
E+ R+ +EEE + ++ +K++L+ EL+ ++ E K++ EK TE K+K E
Sbjct: 943 ELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEE 1002
Query: 983 EMAGLDEIIAKLTKEKKALQEAHQQALDDLQVEEDKVNSLSKSKVKLEQQVDDLEGSLEQ 1042
++ L++ +KL+KE+K L++ + EE+KV SL+K ++K E + D+E L +
Sbjct: 1003 DLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRK 1062
Query: 1043 EKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQVL 1102
E+K R +LE+ KR+L+G+ QE +++ + +L +L +KE ++ ++ EDE
Sbjct: 1063 EEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGA 1122
Query: 1103 ALQLQKKLKENQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQ 1162
QL K L+E QA + E +E+LE+ER AR K EK R DL ELE + LE+ +T+ Q
Sbjct: 1123 RAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQ 1182
Query: 1163 IEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKE 1222
E+ KRE E ++++ LEE T HEA LR++H ++ EL EQ++ +R K EK
Sbjct: 1183 QELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKT 1242
Query: 1223 KSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKL 1282
+ + E+ ++ + + + A+ E+ R LE Q E + + + +R+ + + +
Sbjct: 1243 RLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRA 1302
Query: 1283 QTENGELARQLEEKEALISQLTRGKLSYTQQMEDLKRQLEEEGKAKNALAHALQSARHDC 1342
Q E ++ L E E+ +L++ S Q+ D + L+EE +AK AL +++ +
Sbjct: 1303 QAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEA 1362
Query: 1343 DLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDA 1402
LREQ EEE A+ R L A +++++WR + E +A E EEA+++ A+ +
Sbjct: 1363 AGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEA-GALEAGEEARRRAAREAEAL 1421
Query: 1403 EEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKY 1462
+ + LE+ + RLQ E++D +D+E+ + L+KKQR FD++LAE K
Sbjct: 1422 TQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAV 1481
Query: 1463 EESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGG 1522
+ E E ++ E R L A EE E E +R+N+ L+ E+ L + G
Sbjct: 1482 LRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVG 1541
Query: 1523 KNVHELEKVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKD 1582
K+VHELE+ + E +L++ + E E L E LR ++ +K + ER L +D
Sbjct: 1542 KSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRD 1601
Query: 1583 EEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLNEMEIQLSHANRMAAEAQ 1642
E E+ +R + + + D E + R + +KK+EG+L E++ Q++ A + EA
Sbjct: 1602 EAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAV 1661
Query: 1643 KQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRK 1702
KQ++ +Q+ +K+ ++++ + +++ E+R L+AE+ L+ + ++R+R+
Sbjct: 1662 KQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARR 1721
Query: 1703 LAEQELIETSERVQLLHSQNTSLINQKKKMESDLTQLQSEVEEAVQECRNAEEKAKKAIT 1762
A+Q+ E ++ V + +++ +K+++E L QL+ E+EE ++ +K +
Sbjct: 1722 QAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLL 1781
Query: 1763 DAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVR 1822
+ EL E+ SA E ++ +E+ I++L+ RL E + A K + LE+++
Sbjct: 1782 QVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLA 1841
Query: 1823 ELEGELEAEQKRNAESVKGMRKSERRIKELTYQTEEDKKNLLRLQDLVDKLQLKVKAYKR 1882
+ E +LE E + S K +R++E+R+KE+ Q EE+++ +L+D ++K L+VK KR
Sbjct: 1842 QAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKR 1901
Query: 1883 QAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSR 1927
Q EEAEE+A+ + R++Q EL++ E A+ +V LR + R
Sbjct: 1902 QLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLR 1946
Score = 236 bits (601), Expect = 2e-61
Identities = 217/956 (22%), Positives = 432/956 (45%), Gaps = 61/956 (6%)
Query: 837 KIKPLLKSAETEKEMATMKEEFGRIKETLEKSEAR----RKELEEKMVSLLQEKNDLQLQ 892
K++ ++ + E KEE GR + LEK + R EL+E+MV Q +L+ Q
Sbjct: 1044 KLRLKYEATIADMEDRLRKEEKGR--QELEKLKRRLDGESSELQEQMVEQQQRAEELRAQ 1101
Query: 893 VQAEQDNLNDAEERCD-------QLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKL 945
+ +++ L A R + QL+K+ + +A + E E LE E + ++R L
Sbjct: 1102 LGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDL 1161
Query: 946 EDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAH 1005
+E L+ +++D TL ++ + + +TE L+E + L++ H
Sbjct: 1162 GEELEALRGELED---TLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRH 1218
Query: 1006 QQALDDL--QVEEDK--VNSLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDL 1061
QAL +L Q+E+ + + K+++ LE +V +L L + R + E+ +R+LE L
Sbjct: 1219 GQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQL 1278
Query: 1062 KLTQESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQVLALQLQKKLKENQARIEELE 1121
+ Q D E + + EKL++ + ++ + + + + ++L K+L +A++ + +
Sbjct: 1279 QEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQ 1338
Query: 1122 EELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLE 1181
E L+ E A+ + + E + E+LEE A + +A+ + RR E
Sbjct: 1339 ELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQE 1398
Query: 1182 EATLQHEATAAALRKKHADS------VAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTS 1235
E EA A R+ ++ +AE E +D L+R +++L++E LDD T
Sbjct: 1399 EEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQE-------LDDATM 1451
Query: 1236 NMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQTENGELARQLEE 1295
++EQ + + LEK R + E + + A + + + L R LEE
Sbjct: 1452 DLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEE 1511
Query: 1296 KEALISQLTRGKLSYTQQMEDLKRQLEEEGKAKNALAHALQSARHDCDLLREQYEEETEA 1355
++ +L R + ++E L ++ GK+ + L A + A + LR Q E +
Sbjct: 1512 EQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDE 1571
Query: 1356 KAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSS 1415
+ + V +T++E D R E EE +++LA++L+DAE + + +
Sbjct: 1572 LTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTL 1631
Query: 1416 LEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELES---- 1471
+ +L+ E+E+L + + K+ R + E ++ EE+++ E
Sbjct: 1632 AVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQ 1691
Query: 1472 ---SQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGKNVHEL 1528
S+K + L E+ +L+ E L R + Q++ ++ +++ G + +
Sbjct: 1692 NRESEKRLKGLEAEVLRLQ-------EELAASDRARRQAQQDRDEMADEVANGNLSKAAI 1744
Query: 1529 EKVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEI--ERKLAEKDEEME 1586
+ ++QLE +L+ LEE +++ E + + L+ + E+ ER + K E
Sbjct: 1745 LEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAK---AE 1801
Query: 1587 QAKRNHQRVVDSLQTSL---DAETRSRNEVLRVKKKMEGDLNEMEIQLSHANRMAAEAQK 1643
++ +R + L+ L DA R+R+++ +E L + E QL R + K
Sbjct: 1802 SGRQQLERQIQELRGRLGEEDAGARARHKMTIAA--LESKLAQAEEQLEQETRERILSGK 1859
Query: 1644 QVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKL 1703
V+ + LK+ +Q+++ R D L++ + R L+ +LEE + + R+
Sbjct: 1860 LVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRR 1919
Query: 1704 AEQELIETSERVQLLHSQNTSLINQKKKMESDLT----QLQSEVEEAVQECRNAEE 1755
++EL + +E + ++ + T+L N+ ++ T + +EE V AEE
Sbjct: 1920 LQRELEDVTESAESMNREVTTLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEEAEE 1975
Score = 71.2 bits (173), Expect = 9e-12
Identities = 71/306 (23%), Positives = 140/306 (45%), Gaps = 25/306 (8%)
Query: 1630 QLSHANRMAAEAQKQVKSLQ---SLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAE 1686
+L + ++ ++V LQ + L++ + +L + +RA +L A E L A
Sbjct: 877 ELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAEL---CAEAEETRGRLAAR 933
Query: 1687 LEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMESDLTQLQSEVEEA 1746
+EL VV + E ++ E+E E S ++Q +KK+++ + +L++ +E
Sbjct: 934 KQELELVVSELEA--RVGEEE--ECSRQMQ----------TEKKRLQQHIQELEAHLE-- 977
Query: 1747 VQECRNAEEKAKKAITDAAM--MAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQ 1804
+E + + +K T+A M E+L +D ++ L + +K +E + + + E E+
Sbjct: 978 AEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEE 1037
Query: 1805 IALKGGKKQLQKLEARVRELEGELEAEQKRNAESVKGMRKSERRIKELTYQTEEDKKNLL 1864
+K K K EA + ++E L E+K E K R+ + EL Q E ++
Sbjct: 1038 -KVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAE 1096
Query: 1865 RLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRA 1924
L+ + + + +++A +AE+ L R+ Q L EA+E + K
Sbjct: 1097 ELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEK 1156
Query: 1925 KSRDIG 1930
+ RD+G
Sbjct: 1157 QRRDLG 1162
>gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens]
Length = 2036
Score = 1285 bits (3324), Expect = 0.0
Identities = 726/1942 (37%), Positives = 1150/1942 (59%), Gaps = 63/1942 (3%)
Query: 38 FVPDDKEEFVKAKILSREGGKVIAETE---NGKTVTVKEDQVLQQNPPKFDKIEDMAMLT 94
+VP + F A + R+ G+ AE E +G+ + + DQ+ + NPPKF K EDMA LT
Sbjct: 57 WVPSELHGFEAAAL--RDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMAELT 114
Query: 95 FLHEPAVLFNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNAEVVAAYRGKKRSEAPPHI 154
L+E +VL NL+ERY + +IYTYSGLFCV +NPYK LP+Y +V YRGKKR E PPH+
Sbjct: 115 CLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVPPHV 174
Query: 155 FSISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFASIAAIGDRGKKDN----- 209
+++++ AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY A +A+ +G+K+
Sbjct: 175 YAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVAS-SPKGRKEPGVPAS 233
Query: 210 -ANANKGTLEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYL 268
+ + G LE Q++QANP LEAFGNAKTV+NDNSSRFGKFIRI+F G + A+IETYL
Sbjct: 234 VSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYL 293
Query: 269 LEKSRVIFQLKAERNYHIFYQILSNKKPELLDMLLVTNNPYDYAFVSQGEVSVASIDDSE 328
LEKSR I Q K E ++HIFYQ+L +L LL+ + Y F++ G S + E
Sbjct: 294 LEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSH-YRFLTNGPSSSPG-QERE 351
Query: 329 ELMATDSAFDVLGFTSEEKAGVYKLTGAIMHYGNMKFKQKQREEQAEPDGTEDADKSAYL 388
T + VLGF+ EE + ++ A++ +GN+ K+++ +QA A K L
Sbjct: 352 LFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRL 411
Query: 389 MGLNSADLLKGLCHPRVKVGNEYVTKGQSVQQVYYSIGALAKAVYEKMFNWMVTRINATL 448
+GL D + L PR+KVG +YV K Q+ +Q +++ ALAKA YE++F W+V R+N L
Sbjct: 412 LGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRAL 471
Query: 449 ETKQPRQ--YFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEG 506
+ + PRQ F+G+LDIAGFEIF NSFEQLCIN+TNEKLQQ FNH MFVLEQEEY++EG
Sbjct: 472 D-RSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREG 530
Query: 507 IEWTFIDFGMDLQACIDLIEKPM---GIMSILEEECMFPKATDMTFKAKLYDNHLGKSNN 563
I WTF+DFG+DLQ CIDLIE+P G++++L+EEC FPKATD +F K+ G
Sbjct: 531 IPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQ-GGHPK 589
Query: 564 FQKPRNIKGKQEAHFSLIHYAGTVDYNILGWLEKNKDPLNETVVALYQKSSLKLMATLFS 623
FQ+PR+++ +A FS++HYAG VDY WL KN DPLN+ V AL +S+ +L A ++
Sbjct: 590 FQRPRHLR--DQADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWK 647
Query: 624 -------------SYATADTGDSGKSK-------------------------GGKKKGSS 645
S+ + G + + GG+ +
Sbjct: 648 DEHGGFQQFSFLGSFPPSPPGSAERCSSAISPPGVEGIVGLEQVSSLGDGPPGGRPRRGM 707
Query: 646 FQTVSALHRENLNKLMTNLRTTHPHFVRCIIPNERKAPGVMDNPLVMHQLRCNGVLEGIR 705
F+TV L++E+L++LM L T+P FVRCI+PN K G ++ LV+ QLRCNGVLEGIR
Sbjct: 708 FRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIR 767
Query: 706 ICRKGFPNRILYGDFRQRYRILNPVAIPEGQFIDSRKGTEKLLSSLDIDHNQYKFGHTKV 765
ICR+GFPNRIL+ +FRQRY IL P AIP+G F+D ++ EK++ +L++D N Y+ G +K+
Sbjct: 768 ICRQGFPNRILFQEFRQRYEILTPNAIPKG-FMDGKQACEKMIQALELDPNLYRVGQSKI 826
Query: 766 FFKAGLLGLLEEMRDERLSRIITRMQAQARGQLMRIEFKKIVERRDALLVIQWNIRAFMG 825
FF+AG+L LEE RD +++ II QA ARG L R F+K +++ AL V+Q N A++
Sbjct: 827 FFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAAYLK 886
Query: 826 VKNWPWMKLYFKIKPLLKSAETEKEMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQE 885
+++W W +L+ K+KPLL+ ++ + +E +++E ++S EL+ ++ L +E
Sbjct: 887 LRHWQWWRLFTKVKPLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEE 946
Query: 886 KNDLQLQVQAEQDNLNDAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKL 945
+ L Q++AE + +AEE +L K +LE V E+ R+ +EEE + ++ +K++L
Sbjct: 947 RARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRL 1006
Query: 946 EDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAH 1005
+ EL+ ++ E K++ EK TE K+K E++ L++ +KL+KE+K L++
Sbjct: 1007 QQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRL 1066
Query: 1006 QQALDDLQVEEDKVNSLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQ 1065
+ EE+KV SL+K ++K E + D+E L +E+K R +LE+ KR+L+G+ Q
Sbjct: 1067 AEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQ 1126
Query: 1066 ESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQVLALQLQKKLKENQARIEELEEELE 1125
E +++ + +L +L +KE ++ ++ EDE QL K L+E QA + E +E+LE
Sbjct: 1127 EQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLE 1186
Query: 1126 AERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATL 1185
+ER AR K EK R DL ELE + LE+ +T+ Q E+ KRE E ++++ LEE T
Sbjct: 1187 SERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETR 1246
Query: 1186 QHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKA 1245
HEA LR++H ++ EL EQ++ +R K EK + + E+ ++ + + + A+
Sbjct: 1247 IHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQ 1306
Query: 1246 NLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQTENGELARQLEEKEALISQLTR 1305
E+ R LE Q E + + + +R+ + + + Q E ++ L E E+ +L++
Sbjct: 1307 EGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSK 1366
Query: 1306 GKLSYTQQMEDLKRQLEEEGKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSK 1365
S Q+ D + L+EE +AK AL +++ + LREQ EEE A+ R L
Sbjct: 1367 ELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQT 1426
Query: 1366 ANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQN 1425
A +++++WR + E +A E EEA+++ A+ + + + LE+ + RLQ
Sbjct: 1427 AQAQLSEWRRRQEEEA-GALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQ 1485
Query: 1426 EIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFK 1485
E++D +D+E+ + L+KKQR FD++LAE K + E E ++ E R
Sbjct: 1486 ELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALS 1545
Query: 1486 LKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQSA 1545
L A EE E E +R+N+ L+ E+ L + GK+VHELE+ + E +L++
Sbjct: 1546 LTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQ 1605
Query: 1546 LEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHQRVVDSLQTSLDA 1605
+ E E L E LR ++ +K + ER L +DE E+ +R + + + D
Sbjct: 1606 VTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDE 1665
Query: 1606 ETRSRNEVLRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRA 1665
E + R + +KK+EG+L E++ Q++ A + EA KQ++ +Q+ +K+ ++++ +
Sbjct: 1666 ERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTS 1725
Query: 1666 NDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSL 1725
+++ E+R L+AE+ L+ + ++R+R+ A+Q+ E ++ V + ++
Sbjct: 1726 REEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAI 1785
Query: 1726 INQKKKMESDLTQLQSEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMK 1785
+ +K+++E L QL+ E+EE ++ +K + + EL E+ SA E +
Sbjct: 1786 LEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGR 1845
Query: 1786 KNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELEGELEAEQKRNAESVKGMRKS 1845
+ +E+ I++L+ RL E + A K + LE+++ + E +LE E + S K +R++
Sbjct: 1846 QQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVRRA 1905
Query: 1846 ERRIKELTYQTEEDKKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHEL 1905
E+R+KE+ Q EE+++ +L+D ++K L+VK KRQ EEAEE+A+ + R++Q EL
Sbjct: 1906 EKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQREL 1965
Query: 1906 DEAEERADIAESQVNKLRAKSR 1927
++ E A+ +V LR + R
Sbjct: 1966 EDVTESAESMNREVTTLRNRLR 1987
Score = 236 bits (601), Expect = 2e-61
Identities = 217/956 (22%), Positives = 432/956 (45%), Gaps = 61/956 (6%)
Query: 837 KIKPLLKSAETEKEMATMKEEFGRIKETLEKSEAR----RKELEEKMVSLLQEKNDLQLQ 892
K++ ++ + E KEE GR + LEK + R EL+E+MV Q +L+ Q
Sbjct: 1085 KLRLKYEATIADMEDRLRKEEKGR--QELEKLKRRLDGESSELQEQMVEQQQRAEELRAQ 1142
Query: 893 VQAEQDNLNDAEERCD-------QLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKL 945
+ +++ L A R + QL+K+ + +A + E E LE E + ++R L
Sbjct: 1143 LGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDL 1202
Query: 946 EDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAH 1005
+E L+ +++D TL ++ + + +TE L+E + L++ H
Sbjct: 1203 GEELEALRGELED---TLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRH 1259
Query: 1006 QQALDDL--QVEEDK--VNSLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDL 1061
QAL +L Q+E+ + + K+++ LE +V +L L + R + E+ +R+LE L
Sbjct: 1260 GQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQL 1319
Query: 1062 KLTQESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQVLALQLQKKLKENQARIEELE 1121
+ Q D E + + EKL++ + ++ + + + + ++L K+L +A++ + +
Sbjct: 1320 QEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQ 1379
Query: 1122 EELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLE 1181
E L+ E A+ + + E + E+LEE A + +A+ + RR E
Sbjct: 1380 ELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQE 1439
Query: 1182 EATLQHEATAAALRKKHADS------VAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTS 1235
E EA A R+ ++ +AE E +D L+R +++L++E LDD T
Sbjct: 1440 EEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQE-------LDDATM 1492
Query: 1236 NMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQTENGELARQLEE 1295
++EQ + + LEK R + E + + A + + + L R LEE
Sbjct: 1493 DLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEE 1552
Query: 1296 KEALISQLTRGKLSYTQQMEDLKRQLEEEGKAKNALAHALQSARHDCDLLREQYEEETEA 1355
++ +L R + ++E L ++ GK+ + L A + A + LR Q E +
Sbjct: 1553 EQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDE 1612
Query: 1356 KAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSS 1415
+ + V +T++E D R E EE +++LA++L+DAE + + +
Sbjct: 1613 LTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTL 1672
Query: 1416 LEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELES---- 1471
+ +L+ E+E+L + + K+ R + E ++ EE+++ E
Sbjct: 1673 AVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQ 1732
Query: 1472 ---SQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGKNVHEL 1528
S+K + L E+ +L+ E L R + Q++ ++ +++ G + +
Sbjct: 1733 NRESEKRLKGLEAEVLRLQ-------EELAASDRARRQAQQDRDEMADEVANGNLSKAAI 1785
Query: 1529 EKVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEI--ERKLAEKDEEME 1586
+ ++QLE +L+ LEE +++ E + + L+ + E+ ER + K E
Sbjct: 1786 LEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAK---AE 1842
Query: 1587 QAKRNHQRVVDSLQTSL---DAETRSRNEVLRVKKKMEGDLNEMEIQLSHANRMAAEAQK 1643
++ +R + L+ L DA R+R+++ +E L + E QL R + K
Sbjct: 1843 SGRQQLERQIQELRGRLGEEDAGARARHKMTIAA--LESKLAQAEEQLEQETRERILSGK 1900
Query: 1644 QVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKL 1703
V+ + LK+ +Q+++ R D L++ + R L+ +LEE + + R+
Sbjct: 1901 LVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRR 1960
Query: 1704 AEQELIETSERVQLLHSQNTSLINQKKKMESDLT----QLQSEVEEAVQECRNAEE 1755
++EL + +E + ++ + T+L N+ ++ T + +EE V AEE
Sbjct: 1961 LQRELEDVTESAESMNREVTTLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEEAEE 2016
Score = 71.2 bits (173), Expect = 9e-12
Identities = 71/306 (23%), Positives = 140/306 (45%), Gaps = 25/306 (8%)
Query: 1630 QLSHANRMAAEAQKQVKSLQ---SLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAE 1686
+L + ++ ++V LQ + L++ + +L + +RA +L A E L A
Sbjct: 918 ELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAEL---CAEAEETRGRLAAR 974
Query: 1687 LEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMESDLTQLQSEVEEA 1746
+EL VV + E ++ E+E E S ++Q +KK+++ + +L++ +E
Sbjct: 975 KQELELVVSELEA--RVGEEE--ECSRQMQ----------TEKKRLQQHIQELEAHLE-- 1018
Query: 1747 VQECRNAEEKAKKAITDAAM--MAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQ 1804
+E + + +K T+A M E+L +D ++ L + +K +E + + + E E+
Sbjct: 1019 AEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEE 1078
Query: 1805 IALKGGKKQLQKLEARVRELEGELEAEQKRNAESVKGMRKSERRIKELTYQTEEDKKNLL 1864
+K K K EA + ++E L E+K E K R+ + EL Q E ++
Sbjct: 1079 -KVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAE 1137
Query: 1865 RLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRA 1924
L+ + + + +++A +AE+ L R+ Q L EA+E + K
Sbjct: 1138 ELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEK 1197
Query: 1925 KSRDIG 1930
+ RD+G
Sbjct: 1198 QRRDLG 1203
>gi|215982791 myosin VA isoform 1 [Homo sapiens]
Length = 1855
Score = 617 bits (1592), Expect = e-176
Identities = 452/1500 (30%), Positives = 752/1500 (50%), Gaps = 151/1500 (10%)
Query: 38 FVPDDKEEFVKAKILS--REGGKVIA-ETENGKTVTVKEDQVLQQ-----NPPKFDKIED 89
++PD +E + A++L + G KV+ E GK + D ++ NP D
Sbjct: 14 WIPDPEEVWKSAELLKDYKPGDKVLLLHLEEGKDLEYHLDPKTKELPHLRNPDILVGEND 73
Query: 90 MAMLTFLHEPAVLFNLKERYA-AWMIYTYSGLFCVTVNPYKWLPVYNAEVVAAYRGKKRS 148
+ L++LHEPAVL NL+ R+ + +IYTY G+ V +NPY+ LP+Y +++ AY G+
Sbjct: 74 LTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAYSGQNMG 133
Query: 149 EAPPHIFSISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFASIAAIGDRGKKD 208
+ PHIF++++ AY+ M D NQSI+++GESGAGKTV+ K ++YFA+++
Sbjct: 134 DMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSG-------- 185
Query: 209 NANANKGTLEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYL 268
+A++ +E++++ +NP +E+ GNAKT RNDNSSRFGK+I I F ++ A++ TYL
Sbjct: 186 --SASEANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMRTYL 243
Query: 269 LEKSRVIFQLKAERNYHIFYQILSNKKPELLDMLLVTNNPYDYAFVSQGEVSVAS-IDDS 327
LEKSRV+FQ + ERNYHIFYQ+ ++ K ML + N ++ + QG V +DD+
Sbjct: 244 LEKSRVVFQAEEERNYHIFYQLCASAKLPEFKMLRL-GNADNFNYTKQGGSPVIEGVDDA 302
Query: 328 EELMATDSAFDVLGFTSEEKAGVYKLTGAIMHYGNMKFKQKQREEQAEPDGTEDADKSAY 387
+E+ T A +LG + + G++++ I+H GN+ F + + P E
Sbjct: 303 KEMAHTRQACTLLGISESHQMGIFRILAGILHLGNVGFTSRDADSCTIPPKHEPLCIFCD 362
Query: 388 LMGLNSADLLKGLCHPRVKVGNEYVTKGQSVQQVYYSIGALAKAVYEKMFNWMVTRINAT 447
LMG++ ++ LCH ++ E K S Q + ALAK +Y K+FNW+V +N
Sbjct: 363 LMGVDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVDNVNQA 422
Query: 448 LETKQPRQYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGI 507
L + + FIGVLDI GFE F+ NSFEQ CIN+ NEKLQQ FN H+F LEQEEY KE I
Sbjct: 423 LHSAVKQHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEQI 482
Query: 508 EWTFIDFGMDLQACIDLIEKPMGIMSILEEECMFPKATDMTFKAKLYDNHLGKSNNFQKP 567
WT IDF D Q CI+LIE +GI+ +L+EEC PK TD T+ KLY+ HL K F+KP
Sbjct: 483 PWTLIDF-YDNQPCINLIESKLGILDLLDEECKMPKGTDDTWAQKLYNTHLNKCALFEKP 541
Query: 568 RNIKGKQEAHFSLIHYAGTVDYNILGWLEKNKDPLNETVVALYQKSSLKLMATLFSSYAT 627
R F + H+A V+Y G+LEKNKD + E + + + S K++ LF
Sbjct: 542 R----LSNKAFIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLPELFQDDEK 597
Query: 628 ADTGDSGKSKG----------------GKKKGSSFQTVSALHRENLNKLMTNLRTTHPHF 671
A + S S G G+ +TV R +L+ LM L T PH+
Sbjct: 598 AISPTSATSSGRTPLTRTPAKPTKGRPGQMAKEHKKTVGHQFRNSLHLLMETLNATTPHY 657
Query: 672 VRCIIPNERKAPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRILNPVA 731
VRCI PN+ K P D + QLR GVLE IRI GFP+R Y +F RYR+L
Sbjct: 658 VRCIKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRVL---- 713
Query: 732 IPEGQFIDSRKGT-EKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLSRIITRM 790
+ + + RK T + +L L +D ++Y+FG TK+FF+AG + LE++R ++L R+
Sbjct: 714 MKQKDVLSDRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKLRADKLRAACIRI 773
Query: 791 QAQARGQLMRIEFKKIVERRDALLVIQWNIRAFMG---------VKNWPWMKLYFKIKPL 841
Q RG L+R KK + R A + +Q +R + K ++ Y+++ +
Sbjct: 774 QKTIRGWLLR---KKYLRMRKAAITMQRYVRGYQARCYAKFLRRTKAATIIQKYWRMYVV 830
Query: 842 LKSAETEKEMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQE----------KNDL-- 889
+ + + + + + ++ L ++ R+ E K V + + K +
Sbjct: 831 RRRYKIRRAATIVLQSY--LRGFLARNRYRKILREHKAVIIQKRVRGWLARTHYKRSMHA 888
Query: 890 ---------QLQVQAEQDNLNDAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTA 940
++ + E L ++ K I +E K+ ++ +++++ + L
Sbjct: 889 IIYLQCCFRRMMAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVE 948
Query: 941 KKRKLE----DECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTK 996
K LE E +L+ D++ L+L+ E+E +V +L EE+A L + + +
Sbjct: 949 KLTNLEGIYNSETEKLRSDLERLQLS----EEEAKVATGRVLSLQEEIAKLRKDLEQTRS 1004
Query: 997 EKKALQEAHQQALDDLQVEEDKVNSLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRK 1056
EKK ++E A Q E V++L + L+Q+ + L + Q+ K E ++K
Sbjct: 1005 EKKCIEE---HADRYKQETEQLVSNLKEENTLLKQEKEALNHRIVQQAKEM--TETMEKK 1059
Query: 1057 LEGDLKLTQESIMDLENDKLQLEEKLKKKEFD-INQQNSKIEDEQVLALQLQKKLKENQA 1115
L ++ T++ +DL +++L+ + L EF + ++ +++E L + + K
Sbjct: 1060 L---VEETKQLELDLNDERLRYQNLL--NEFSRLEERYDDLKEEMTLMVHVP---KPGHK 1111
Query: 1116 RIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMN-----KKRE 1170
R + E+E +++ E+E+I R EE V ++M+ +KR
Sbjct: 1112 RTDSTHSSNESEYIFSSEI--------AEMEDIPSRTEEP-SEKKVPLDMSLFLKLQKRV 1162
Query: 1171 AEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEL 1230
E ++ ++ +++ + E + K + G +++ +Q+LE E + K EL
Sbjct: 1163 TELEQEKQVMQDELDRKEEQVLRSKAKEEERPQIRGAELEYESLKRQELESENKKLKNEL 1222
Query: 1231 DDVTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQTENGELA 1290
+++ + + + A YRV +E+ + ++ ++ +L
Sbjct: 1223 NELRKALSE--------KSAPEVTAPGAPAYRVLMEQLTSVSEELDVRKEEVLILRSQLV 1274
Query: 1291 RQLEEKEALISQLTRGKLS-YTQQMEDLKRQLE--EEGKAKNALAHALQSARHDCDLLRE 1347
Q KEA+ + + ++ T +ED+++ + E +A L +S+ D L E
Sbjct: 1275 SQ---KEAIQPKDDKNTMTDSTILLEDVQKMKDKGEIAQAYIGLKETNRSSALDYHELNE 1331
Query: 1348 QYE--EETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKK-------LAQR 1398
E E + R+L S++ + +E +A E++ K++ LAQ
Sbjct: 1332 DGELWLVYEGLKQANRLL---ESQLQSQKRSHENEAEALRGEIQSLKEENNRQQQLLAQN 1388
Query: 1399 LQDAEEA-VEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAE 1457
LQ EA +EA SL+ RL NE DLM +E+ + L K+ + F K + E
Sbjct: 1389 LQLPPEARIEA------SLQHEITRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKIGE 1442
Score = 74.3 bits (181), Expect = 1e-12
Identities = 121/585 (20%), Positives = 244/585 (41%), Gaps = 87/585 (14%)
Query: 1291 RQLEEKEALISQLTRGKLSYTQQMEDLKRQLEEEGKAKNALAHALQSARHDCDLLREQYE 1350
++L+ + + + + + ++ L+R+++E+ K L L + L Y
Sbjct: 906 KKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTN-------LEGIYN 958
Query: 1351 EETEA-KAELQRV-LSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEA 1408
ETE +++L+R+ LS+ ++VA R + EE+ + +K L Q +
Sbjct: 959 SETEKLRSDLERLQLSEEEAKVATGRV------LSLQEEIAKLRKDLEQTRSEK------ 1006
Query: 1409 VNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSE 1468
KC +E+ R + E E L+ +++ N +K+ +I+ + K+ E + +
Sbjct: 1007 ---KC--IEEHADRYKQETEQLVSNLKEENTLLK--QEKEALNHRIVQQAKEMTETMEKK 1059
Query: 1469 LESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGKNV--- 1525
L +E + L +L + Y+ L + +L+EE++ + G K
Sbjct: 1060 LV---EETKQLELDLNDERLRYQNLLNEFSRLEERYDDLKEEMTLMVHVPKPGHKRTDST 1116
Query: 1526 ---HELEKVRKQLEVEKLELQSALEE-AEASLEHEEGKILRAQ---LEFNQIKAEIERKL 1578
+E E + E ++ S EE +E + + L+ Q E Q K ++ +L
Sbjct: 1117 HSSNESEYIFSSEIAEMEDIPSRTEEPSEKKVPLDMSLFLKLQKRVTELEQEKQVMQDEL 1176
Query: 1579 AEKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLNEMEIQLSH--ANR 1636
K+E++ ++K + L+ E+ R E+ KK++ +LNE+ LS A
Sbjct: 1177 DRKEEQVLRSKAKEEERPQIRGAELEYESLKRQELESENKKLKNELNELRKALSEKSAPE 1236
Query: 1637 MAAEAQKQVKSLQSLLKDTQIQLD-----------------DAVRANDD---LKENIAIV 1676
+ A + L L +LD +A++ DD + ++ ++
Sbjct: 1237 VTAPGAPAYRVLMEQLTSVSEELDVRKEEVLILRSQLVSQKEAIQPKDDKNTMTDSTILL 1296
Query: 1677 ERRNNLL-QAELEELRAVVEQTERSRKLAEQELIETSE----------RVQLLHSQNTSL 1725
E + + E+ + +++T RS L EL E E +LL SQ L
Sbjct: 1297 EDVQKMKDKGEIAQAYIGLKETNRSSALDYHELNEDGELWLVYEGLKQANRLLESQ---L 1353
Query: 1726 INQKKKMESDLTQLQSEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMK 1785
+QK+ E++ L+ E++ +E ++ + + +L E A L+
Sbjct: 1354 QSQKRSHENEAEALRGEIQSLKEENNRQQQLLAQNL--------QLPPEARIEASLQHEI 1405
Query: 1786 KNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELE-GELE 1829
+ DL +L++ ++ K KKQL+ ++ ELE G++E
Sbjct: 1406 TRLTNENLDLMEQLEKQDKTVRK-LKKQLKVFAKKIGELEVGQME 1449
Score = 64.3 bits (155), Expect = 1e-09
Identities = 76/350 (21%), Positives = 157/350 (44%), Gaps = 41/350 (11%)
Query: 1542 LQSALEEAEASLEHEEGKILRAQLE-FNQIKAEIERKLAEKDEEMEQAKRNHQRVVDSLQ 1600
LQ A E ++ KI +E + ++ +E K+ + ++++ ++++ +V+ L
Sbjct: 892 LQCCFRRMMAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKL- 950
Query: 1601 TSLDAETRSRNEVLRVK-KKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQL 1659
T+L+ S E LR ++++ E ++ + E K K L+ + +
Sbjct: 951 TNLEGIYNSETEKLRSDLERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKCIE 1010
Query: 1660 DDAVRANDDLKENIAIVERRNNLLQAELEELR-AVVEQTERSRKLAEQELIETSERVQL- 1717
+ A R + ++ ++ ++ N LL+ E E L +V+Q + + E++L+E +++++L
Sbjct: 1011 EHADRYKQETEQLVSNLKEENTLLKQEKEALNHRIVQQAKEMTETMEKKLVEETKQLELD 1070
Query: 1718 -----LHSQNTSLINQKKKMESDLTQLQSEV----------EEAVQECRNAEEKAKKAIT 1762
L QN L+N+ ++E L+ E+ + ++ E +
Sbjct: 1071 LNDERLRYQN--LLNEFSRLEERYDDLKEEMTLMVHVPKPGHKRTDSTHSSNESEYIFSS 1128
Query: 1763 DAAMMAE---------ELKKEQDTSAHLERMKK--NMEQTIKDLQHRLDEAEQIALKGGK 1811
+ A M + E K D S L+ K+ +EQ + +Q LD E+ L+
Sbjct: 1129 EIAEMEDIPSRTEEPSEKKVPLDMSLFLKLQKRVTELEQEKQVMQDELDRKEEQVLRSKA 1188
Query: 1812 KQLQKLEARVRELE------GELEAEQKRNAESVKGMRK--SERRIKELT 1853
K+ ++ + R ELE ELE+E K+ + +RK SE+ E+T
Sbjct: 1189 KEEERPQIRGAELEYESLKRQELESENKKLKNELNELRKALSEKSAPEVT 1238
Score = 47.4 bits (111), Expect = 1e-04
Identities = 62/309 (20%), Positives = 131/309 (42%), Gaps = 74/309 (23%)
Query: 1679 RNNLLQAELEELRAVVEQTERSRKL---AEQELIETSERVQLLHSQNTSLINQKKKMESD 1735
R + + EL++L+ ER +KL E ++++ +V + L+ + +E
Sbjct: 897 RRMMAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGI 956
Query: 1736 LTQLQSEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDL 1795
++ ++ + +EE+AK A + EE+ K ++K++EQT +
Sbjct: 957 YNSETEKLRSDLERLQLSEEEAKVATGRVLSLQEEIAK----------LRKDLEQTRSEK 1006
Query: 1796 QHRLDEAEQIALKGGKKQLQKLEARVRE----LEGELEAEQKRNAESVKGMRKS-ERRIK 1850
+ + A++ K++ ++L + ++E L+ E EA R + K M ++ E+++
Sbjct: 1007 KCIEEHADRY-----KQETEQLVSNLKEENTLLKQEKEALNHRIVQQAKEMTETMEKKLV 1061
Query: 1851 ELTYQTEEDK-------KNLL--------RLQDLVDKLQLKVKAYK-------------- 1881
E T Q E D +NLL R DL +++ L V K
Sbjct: 1062 EETKQLELDLNDERLRYQNLLNEFSRLEERYDDLKEEMTLMVHVPKPGHKRTDSTHSSNE 1121
Query: 1882 -----------------RQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNK--- 1921
R E +E++ ++S F K+Q + E E+ + + ++++
Sbjct: 1122 SEYIFSSEIAEMEDIPSRTEEPSEKKVPLDMSLFLKLQKRVTELEQEKQVMQDELDRKEE 1181
Query: 1922 --LRAKSRD 1928
LR+K+++
Sbjct: 1182 QVLRSKAKE 1190
>gi|215982794 myosin VA isoform 2 [Homo sapiens]
Length = 1828
Score = 616 bits (1589), Expect = e-176
Identities = 448/1489 (30%), Positives = 744/1489 (49%), Gaps = 156/1489 (10%)
Query: 38 FVPDDKEEFVKAKILS--REGGKVIA-ETENGKTVTVKEDQVLQQ-----NPPKFDKIED 89
++PD +E + A++L + G KV+ E GK + D ++ NP D
Sbjct: 14 WIPDPEEVWKSAELLKDYKPGDKVLLLHLEEGKDLEYHLDPKTKELPHLRNPDILVGEND 73
Query: 90 MAMLTFLHEPAVLFNLKERYA-AWMIYTYSGLFCVTVNPYKWLPVYNAEVVAAYRGKKRS 148
+ L++LHEPAVL NL+ R+ + +IYTY G+ V +NPY+ LP+Y +++ AY G+
Sbjct: 74 LTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAYSGQNMG 133
Query: 149 EAPPHIFSISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFASIAAIGDRGKKD 208
+ PHIF++++ AY+ M D NQSI+++GESGAGKTV+ K ++YFA+++
Sbjct: 134 DMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSG-------- 185
Query: 209 NANANKGTLEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYL 268
+A++ +E++++ +NP +E+ GNAKT RNDNSSRFGK+I I F ++ A++ TYL
Sbjct: 186 --SASEANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMRTYL 243
Query: 269 LEKSRVIFQLKAERNYHIFYQILSNKKPELLDMLLVTNNPYDYAFVSQGEVSVAS-IDDS 327
LEKSRV+FQ + ERNYHIFYQ+ ++ K ML + N ++ + QG V +DD+
Sbjct: 244 LEKSRVVFQAEEERNYHIFYQLCASAKLPEFKMLRL-GNADNFNYTKQGGSPVIEGVDDA 302
Query: 328 EELMATDSAFDVLGFTSEEKAGVYKLTGAIMHYGNMKFKQKQREEQAEPDGTEDADKSAY 387
+E+ T A +LG + + G++++ I+H GN+ F + + P E
Sbjct: 303 KEMAHTRQACTLLGISESHQMGIFRILAGILHLGNVGFTSRDADSCTIPPKHEPLCIFCD 362
Query: 388 LMGLNSADLLKGLCHPRVKVGNEYVTKGQSVQQVYYSIGALAKAVYEKMFNWMVTRINAT 447
LMG++ ++ LCH ++ E K S Q + ALAK +Y K+FNW+V +N
Sbjct: 363 LMGVDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVDNVNQA 422
Query: 448 LETKQPRQYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGI 507
L + + FIGVLDI GFE F+ NSFEQ CIN+ NEKLQQ FN H+F LEQEEY KE I
Sbjct: 423 LHSAVKQHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEQI 482
Query: 508 EWTFIDFGMDLQACIDLIEKPMGIMSILEEECMFPKATDMTFKAKLYDNHLGKSNNFQKP 567
WT IDF D Q CI+LIE +GI+ +L+EEC PK TD T+ KLY+ HL K F+KP
Sbjct: 483 PWTLIDF-YDNQPCINLIESKLGILDLLDEECKMPKGTDDTWAQKLYNTHLNKCALFEKP 541
Query: 568 RNIKGKQEAHFSLIHYAGTVDYNILGWLEKNKDPLNETVVALYQKSSLKLMATLFSSYAT 627
R F + H+A V+Y G+LEKNKD + E + + + S K++ LF
Sbjct: 542 R----LSNKAFIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLPELFQDDEK 597
Query: 628 ADTGDSGKSKG----------------GKKKGSSFQTVSALHRENLNKLMTNLRTTHPHF 671
A + S S G G+ +TV R +L+ LM L T PH+
Sbjct: 598 AISPTSATSSGRTPLTRTPAKPTKGRPGQMAKEHKKTVGHQFRNSLHLLMETLNATTPHY 657
Query: 672 VRCIIPNERKAPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRILNPVA 731
VRCI PN+ K P D + QLR GVLE IRI GFP+R Y +F RYR+L
Sbjct: 658 VRCIKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRVL---- 713
Query: 732 IPEGQFIDSRKGT-EKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLSRIITRM 790
+ + + RK T + +L L +D ++Y+FG TK+FF+AG + LE++R ++L R+
Sbjct: 714 MKQKDVLSDRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKLRADKLRAACIRI 773
Query: 791 QAQARGQLMRIEFKKIVERRDALLVIQWNIRAFMG---------VKNWPWMKLYFKIKPL 841
Q RG L+R KK + R A + +Q +R + K ++ Y+++ +
Sbjct: 774 QKTIRGWLLR---KKYLRMRKAAITMQRYVRGYQARCYAKFLRRTKAATIIQKYWRMYVV 830
Query: 842 LKSAETEKEMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQE----------KNDL-- 889
+ + + + + + ++ L ++ R+ E K V + + K +
Sbjct: 831 RRRYKIRRAATIVLQSY--LRGFLARNRYRKILREHKAVIIQKRVRGWLARTHYKRSMHA 888
Query: 890 ---------QLQVQAEQDNLNDAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTA 940
++ + E L ++ K I +E K+ ++ +++++ + L
Sbjct: 889 IIYLQCCFRRMMAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVE 948
Query: 941 KKRKLE----DECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTK 996
K LE E +L+ D++ L+L+ E+E +V +L EE+A L + + +
Sbjct: 949 KLTNLEGIYNSETEKLRSDLERLQLS----EEEAKVATGRVLSLQEEIAKLRKDLEQTRS 1004
Query: 997 EKKALQEAHQQALDDLQVEEDKVNSLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRK 1056
EKK ++E A Q E V++L + L+Q+ + L + Q+ K E ++K
Sbjct: 1005 EKKCIEE---HADRYKQETEQLVSNLKEENTLLKQEKEALNHRIVQQAKEM--TETMEKK 1059
Query: 1057 LEGDLKLTQESIMDLENDKLQLEEKLKKKEFD-INQQNSKIEDEQVLALQLQKKLKENQA 1115
L ++ T++ +DL +++L+ + L EF + ++ +++E L + + K
Sbjct: 1060 L---VEETKQLELDLNDERLRYQNLL--NEFSRLEERYDDLKEEMTLMVHVP---KPGHK 1111
Query: 1116 RIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMN-----KKRE 1170
R + E+E +++ E+E+I R EE V ++M+ +KR
Sbjct: 1112 RTDSTHSSNESEYIFSSEI--------AEMEDIPSRTEEP-SEKKVPLDMSLFLKLQKRV 1162
Query: 1171 AEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEL 1230
E ++ ++ +++ + E + K + G +++ +Q+LE E + K EL
Sbjct: 1163 TELEQEKQVMQDELDRKEEQVLRSKAKEEERPQIRGAELEYESLKRQELESENKKLKNEL 1222
Query: 1231 DDVTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQTENGELA 1290
+++ + + + A YRV +E+ + ++ ++ +L
Sbjct: 1223 NELRKALSE--------KSAPEVTAPGAPAYRVLMEQLTSVSEELDVRKEEVLILRSQLV 1274
Query: 1291 RQLEEKEALISQLTRGKLS-YTQQMEDLKRQLEEEGKAKNALAHALQSARHDCDLLREQY 1349
Q KEA+ + + ++ T +ED+++ K K +A A + LL Q
Sbjct: 1275 SQ---KEAIQPKDDKNTMTDSTILLEDVQKM-----KDKGEIAQAYIGLKETNRLLESQL 1326
Query: 1350 EEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEA-VEA 1408
+ + K + E + E +++ EE ++ LAQ LQ EA +EA
Sbjct: 1327 QSQ------------KRSHENEAEALRGEIQSLK--EENNRQQQLLAQNLQLPPEARIEA 1372
Query: 1409 VNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAE 1457
SL+ RL NE DLM +E+ + L K+ + F K + E
Sbjct: 1373 ------SLQHEITRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKIGE 1415
Score = 76.6 bits (187), Expect = 2e-13
Identities = 117/560 (20%), Positives = 238/560 (42%), Gaps = 64/560 (11%)
Query: 1291 RQLEEKEALISQLTRGKLSYTQQMEDLKRQLEEEGKAKNALAHALQSARHDCDLLREQYE 1350
++L+ + + + + + ++ L+R+++E+ K L L + L Y
Sbjct: 906 KKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTN-------LEGIYN 958
Query: 1351 EETEA-KAELQRV-LSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEA 1408
ETE +++L+R+ LS+ ++VA R + EE+ + +K L Q +
Sbjct: 959 SETEKLRSDLERLQLSEEEAKVATGRV------LSLQEEIAKLRKDLEQTRSEK------ 1006
Query: 1409 VNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSE 1468
KC +E+ R + E E L+ +++ N +K+ +I+ + K+ E + +
Sbjct: 1007 ---KC--IEEHADRYKQETEQLVSNLKEENTLLK--QEKEALNHRIVQQAKEMTETMEKK 1059
Query: 1469 LESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGKNV--- 1525
L +E + L +L + Y+ L + +L+EE++ + G K
Sbjct: 1060 LV---EETKQLELDLNDERLRYQNLLNEFSRLEERYDDLKEEMTLMVHVPKPGHKRTDST 1116
Query: 1526 ---HELEKVRKQLEVEKLELQSALEE-AEASLEHEEGKILRAQ---LEFNQIKAEIERKL 1578
+E E + E ++ S EE +E + + L+ Q E Q K ++ +L
Sbjct: 1117 HSSNESEYIFSSEIAEMEDIPSRTEEPSEKKVPLDMSLFLKLQKRVTELEQEKQVMQDEL 1176
Query: 1579 AEKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLNEMEIQLSH--ANR 1636
K+E++ ++K + L+ E+ R E+ KK++ +LNE+ LS A
Sbjct: 1177 DRKEEQVLRSKAKEEERPQIRGAELEYESLKRQELESENKKLKNELNELRKALSEKSAPE 1236
Query: 1637 MAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAE----LEELRA 1692
+ A + L L +LD VR + L +V ++ + + + +
Sbjct: 1237 VTAPGAPAYRVLMEQLTSVSEELD--VRKEEVLILRSQLVSQKEAIQPKDDKNTMTDSTI 1294
Query: 1693 VVEQTERSRKLAE--QELIETSERVQLLHSQNTSLINQKKKMESDLTQLQSEVEEAVQEC 1750
++E ++ + E Q I E +LL SQ L +QK+ E++ L+ E++ +E
Sbjct: 1295 LLEDVQKMKDKGEIAQAYIGLKETNRLLESQ---LQSQKRSHENEAEALRGEIQSLKEEN 1351
Query: 1751 RNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGG 1810
++ + + +L E A L+ + DL +L++ ++ K
Sbjct: 1352 NRQQQLLAQNL--------QLPPEARIEASLQHEITRLTNENLDLMEQLEKQDKTVRK-L 1402
Query: 1811 KKQLQKLEARVRELE-GELE 1829
KKQL+ ++ ELE G++E
Sbjct: 1403 KKQLKVFAKKIGELEVGQME 1422
Score = 64.3 bits (155), Expect = 1e-09
Identities = 76/350 (21%), Positives = 157/350 (44%), Gaps = 41/350 (11%)
Query: 1542 LQSALEEAEASLEHEEGKILRAQLE-FNQIKAEIERKLAEKDEEMEQAKRNHQRVVDSLQ 1600
LQ A E ++ KI +E + ++ +E K+ + ++++ ++++ +V+ L
Sbjct: 892 LQCCFRRMMAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKL- 950
Query: 1601 TSLDAETRSRNEVLRVK-KKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQL 1659
T+L+ S E LR ++++ E ++ + E K K L+ + +
Sbjct: 951 TNLEGIYNSETEKLRSDLERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKCIE 1010
Query: 1660 DDAVRANDDLKENIAIVERRNNLLQAELEELR-AVVEQTERSRKLAEQELIETSERVQL- 1717
+ A R + ++ ++ ++ N LL+ E E L +V+Q + + E++L+E +++++L
Sbjct: 1011 EHADRYKQETEQLVSNLKEENTLLKQEKEALNHRIVQQAKEMTETMEKKLVEETKQLELD 1070
Query: 1718 -----LHSQNTSLINQKKKMESDLTQLQSEV----------EEAVQECRNAEEKAKKAIT 1762
L QN L+N+ ++E L+ E+ + ++ E +
Sbjct: 1071 LNDERLRYQN--LLNEFSRLEERYDDLKEEMTLMVHVPKPGHKRTDSTHSSNESEYIFSS 1128
Query: 1763 DAAMMAE---------ELKKEQDTSAHLERMKK--NMEQTIKDLQHRLDEAEQIALKGGK 1811
+ A M + E K D S L+ K+ +EQ + +Q LD E+ L+
Sbjct: 1129 EIAEMEDIPSRTEEPSEKKVPLDMSLFLKLQKRVTELEQEKQVMQDELDRKEEQVLRSKA 1188
Query: 1812 KQLQKLEARVRELE------GELEAEQKRNAESVKGMRK--SERRIKELT 1853
K+ ++ + R ELE ELE+E K+ + +RK SE+ E+T
Sbjct: 1189 KEEERPQIRGAELEYESLKRQELESENKKLKNELNELRKALSEKSAPEVT 1238
Score = 47.4 bits (111), Expect = 1e-04
Identities = 62/309 (20%), Positives = 131/309 (42%), Gaps = 74/309 (23%)
Query: 1679 RNNLLQAELEELRAVVEQTERSRKL---AEQELIETSERVQLLHSQNTSLINQKKKMESD 1735
R + + EL++L+ ER +KL E ++++ +V + L+ + +E
Sbjct: 897 RRMMAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGI 956
Query: 1736 LTQLQSEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDL 1795
++ ++ + +EE+AK A + EE+ K ++K++EQT +
Sbjct: 957 YNSETEKLRSDLERLQLSEEEAKVATGRVLSLQEEIAK----------LRKDLEQTRSEK 1006
Query: 1796 QHRLDEAEQIALKGGKKQLQKLEARVRE----LEGELEAEQKRNAESVKGMRKS-ERRIK 1850
+ + A++ K++ ++L + ++E L+ E EA R + K M ++ E+++
Sbjct: 1007 KCIEEHADRY-----KQETEQLVSNLKEENTLLKQEKEALNHRIVQQAKEMTETMEKKLV 1061
Query: 1851 ELTYQTEEDK-------KNLL--------RLQDLVDKLQLKVKAYK-------------- 1881
E T Q E D +NLL R DL +++ L V K
Sbjct: 1062 EETKQLELDLNDERLRYQNLLNEFSRLEERYDDLKEEMTLMVHVPKPGHKRTDSTHSSNE 1121
Query: 1882 -----------------RQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNK--- 1921
R E +E++ ++S F K+Q + E E+ + + ++++
Sbjct: 1122 SEYIFSSEIAEMEDIPSRTEEPSEKKVPLDMSLFLKLQKRVTELEQEKQVMQDELDRKEE 1181
Query: 1922 --LRAKSRD 1928
LR+K+++
Sbjct: 1182 QVLRSKAKE 1190
>gi|153945715 myosin VC [Homo sapiens]
Length = 1742
Score = 608 bits (1568), Expect = e-173
Identities = 444/1430 (31%), Positives = 730/1430 (51%), Gaps = 92/1430 (6%)
Query: 38 FVPDDKEEFVKAKILS--REGGKVIAET-ENGKTVTVK---EDQVLQQNPPKFDKIEDMA 91
++PD +E + A+I R G KV+ E+G + E +NP D+
Sbjct: 14 WIPDPEEVWKSAEIAKDYRVGDKVLRLLLEDGTELDYSVNPESLPPLRNPDILVGENDLT 73
Query: 92 MLTFLHEPAVLFNLKERYA-AWMIYTYSGLFCVTVNPYKWLPVYNAEVVAAYRGKKRSEA 150
L++LHEPAVL NL+ R+A + +IYTYSG+ V +NPYK LP+Y ++ AY G+ +
Sbjct: 74 ALSYLHEPAVLHNLRIRFAESKLIYTYSGIILVAMNPYKQLPIYGDAIIHAYSGQNMGDM 133
Query: 151 PPHIFSISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFASIAAIGDRGKKDNA 210
PHIF++++ AY+ M + NQSI+++GESGAGKTV+ + ++YFA+++ K +
Sbjct: 134 DPHIFAVAEEAYKQMARNNRNQSIIVSGESGAGKTVSARYAMRYFATVS-------KSGS 186
Query: 211 NANKGTLEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLE 270
NA+ +ED+++ +NP EA GNAKT RNDNSSRFGK+ I F ++ A++ TYLLE
Sbjct: 187 NAH---VEDKVLASNPITEAVGNAKTTRNDNSSRFGKYTEISFDEQNQIIGANMSTYLLE 243
Query: 271 KSRVIFQLKAERNYHIFYQILSN-KKPELLDMLLVTNNPYDYAFVSQGEVSVASIDDSEE 329
KSRV+FQ + ERNYHIFYQ+ ++ ++ E + L + ++Y + G + ++D E
Sbjct: 244 KSRVVFQSENERNYHIFYQLCASAQQSEFKHLKLGSAEEFNYTRMG-GNTVIEGVNDRAE 302
Query: 330 LMATDSAFDVLGFTSEEKAGVYKLTGAIMHYGNMKFKQKQREEQAEPDGTEDADKSAYLM 389
++ T F +LGF + + V+K+ AI+H GN++ E + + L+
Sbjct: 303 MVETQKTFTLLGFKEDFQMDVFKILAAILHLGNVQITAVGNERSSVSEDDSHLKVFCELL 362
Query: 390 GLNSADLLKGLCHPRVKVGNEYVTKGQSVQQVYYSIGALAKAVYEKMFNWMVTRINATLE 449
GL S + + LC+ ++ +E V K + Q + ALAK +Y +F+++V RIN L+
Sbjct: 363 GLESGRVAQWLCNRKIVTSSETVVKPMTRPQAVNARDALAKKIYAHLFDFIVERINQALQ 422
Query: 450 TKQPRQYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEW 509
+ FIGVLDI GFE FD NSFEQ CIN+ NEKLQQ FN H+F LEQEEY KE I W
Sbjct: 423 FSGKQHTFIGVLDIYGFETFDVNSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEDIPW 482
Query: 510 TFIDFGMDLQACIDLIEKPMGIMSILEEECMFPKATDMTFKAKLYDNHLGKSNNFQKPRN 569
T IDF D Q IDLIE MGI+ +L+EEC+ P TD + KLY+N + ++ F+KPR
Sbjct: 483 TLIDF-YDNQPVIDLIEAKMGILELLDEECLLPHGTDENWLQKLYNNFVNRNPLFEKPR- 540
Query: 570 IKGKQEAHFSLIHYAGTVDYNILGWLEKNKDPLNETVVALYQKSSLKLMATLF------- 622
F + H+A V+Y G+LEKN+D + + +V + + S L A F
Sbjct: 541 ---MSNTSFVIQHFADKVEYKCEGFLEKNRDTVYDMLVEILRASKFHLCANFFQENPTPP 597
Query: 623 SSYATADTGDSGKSKGGKKKGSSFQTVSALHRENLNKLMTNLRTTHPHFVRCIIPNERKA 682
S + + T S K TV + R +L LM L T PH+VRCI PN+ K
Sbjct: 598 SPFGSMITVKSAKQVIKPNSKHFRTTVGSKFRSSLYLLMETLNATTPHYVRCIKPNDEKL 657
Query: 683 PGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRILNPVAIPEGQFIDSRK 742
P D+ ++ QLR GVLE IRI + +P+R Y +F RY IL + E F D ++
Sbjct: 658 PFEFDSKRIVQQLRACGVLETIRISAQSYPSRWTYIEFYSRYGIL--MTKQELSFSDKKE 715
Query: 743 GTEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLSRIITRMQAQARGQLMRIE 802
+ +L L D NQY+FG TK+FF+AG + LE++R ++L + +Q RG L R
Sbjct: 716 VCKVVLHRLIQDSNQYQFGKTKIFFRAGQVAYLEKLRLDKLRQSCVMVQKHMRGWLQR-- 773
Query: 803 FKKIVERRDALLVIQWNIRAFMGV-KNWPWMKLYFKIKPLLKSAETEKEMATMKEEFGRI 861
KK + R A L+IQ R V K + L ++ + + R+
Sbjct: 774 -KKFLRERRAALIIQQYFRGQQTVRKAITAVALKEAWAAIIIQKHCRGYLVRSLYQLIRM 832
Query: 862 KETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLNDAEERCDQLIKNKIQLEAKV 921
++ +R + +L+E + LQ A + + + N IQL +V
Sbjct: 833 ATITMQAYSRGFLARRRYRKMLEEHKAVILQKYARAWLARRRFQSIRRFVLN-IQLTYRV 891
Query: 922 KEMNERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLT 981
+ + ++LED+ + N L K L + + I LE L K + E K K
Sbjct: 892 QRLQKKLEDQNKENHGLVEKLTSLAALRAGDVEKIQKLEAELEKAATHRRNYEEKGKRYR 951
Query: 982 EEMAGLDEIIAKLTKEKKALQEAHQQALDDLQVEEDKVNSLSKSKVKLEQQVDDLEGSLE 1041
+ ++E +AKL K L+ +Q LQ + +++ K K++ L ++
Sbjct: 952 D---AVEEKLAKLQKHNSELETQKEQIQLKLQEKTEEL------KEKMDNLTKQLFDDVQ 1002
Query: 1042 QEKKVRMDLERA----KRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDINQQNSKIE 1097
+E++ RM LE++ + E ++ +E I L+++K+QL+ ++ + + K E
Sbjct: 1003 KEERQRMLLEKSFELKTQDYEKQIQSLKEEIKALKDEKMQLQHLVEGEH--VTSDGLKAE 1060
Query: 1098 DEQVLALQLQKKLKENQARIEELEEELEAERTARAKVEK----LRSDLSRELEEISERLE 1153
+L K++K I E E+E+E + + VEK + ++ ++ EI+++L
Sbjct: 1061 -----VARLSKQVK----TISEFEKEIELLQAQKIDVEKHVQSQKREMREKMSEITKQLL 1111
Query: 1154 EAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQ 1213
E+ V+ ++ + DLE E A K A V E + Q
Sbjct: 1112 ESYDIEDVRSRLSVE----------DLEHLNEDGELWFAYEGLKKATRVLE-----SHFQ 1156
Query: 1214 RVKQKLEK--EKSEFK-LELDDVTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQR 1270
K EK E FK + L ++++++ + + ++ + R + + + + ++
Sbjct: 1157 SQKDCYEKEIEALNFKVVHLSQEINHLQKLFREENDINESIRHEVTRLTSENMMIPDFKQ 1216
Query: 1271 SLNDFTTQRAKLQTENGELARQLEEK-EALISQLTRGKLSYTQQMEDLKRQLEEEGKAKN 1329
+++ Q+ L+ E A +++ K E L +QL R + Q + L+ Q E K K
Sbjct: 1217 QISELEKQKQDLEIRLNEQAEKMKGKLEELSNQLHRSQEEEGTQRKALEAQNEIHTKEKE 1276
Query: 1330 ALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRT-EEL 1388
L +Q + D L++Q+E E+E K ++ S+ E + E D R ++L
Sbjct: 1277 KLIDKIQEMQEASDHLKKQFETESEVKCNFRQEASRLTLENRD--LEEELDMKDRVIKKL 1334
Query: 1389 EEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNE---IEDLMVDVE 1435
++ K L++ + A + V + + L +++ ++E I++L++D++
Sbjct: 1335 QDQVKTLSKTIGKAND-VHSSSGPKEYLGMLQYKREDEAKLIQNLILDLK 1383
Score = 89.0 bits (219), Expect = 4e-17
Identities = 115/550 (20%), Positives = 242/550 (44%), Gaps = 89/550 (16%)
Query: 1308 LSYTQQMEDLKRQLEEEGKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKAN 1367
+ T +++ L+++LE++ K + L L S L E+ + +AEL++
Sbjct: 885 IQLTYRVQRLQKKLEDQNKENHGLVEKLTSL---AALRAGDVEKIQKLEAELEKA----- 936
Query: 1368 SEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSS-LEKTKHRLQNE 1426
A R YE + + +EE KL + + E E + K E+ K ++ N
Sbjct: 937 ---ATHRRNYEEKGKRYRDAVEEKLAKLQKHNSELETQKEQIQLKLQEKTEELKEKMDNL 993
Query: 1427 IEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKL 1486
+ L DV++ L+K ++ K ++ + +++S ++E ++L E +L
Sbjct: 994 TKQLFDDVQKEERQRMLLEKS----------FELKTQDYEKQIQSLKEEIKALKDEKMQL 1043
Query: 1487 KNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQSAL 1546
++ E EH+ + L+ E++ L++Q+ K + E EK + L+ +K++++ +
Sbjct: 1044 QHLVEG--EHVTS-----DGLKAEVARLSKQV----KTISEFEKEIELLQAQKIDVEKHV 1092
Query: 1547 EEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKD--------------EEMEQAKRNH 1592
+ + + + +I + LE I+ ++ +L+ +D E +++A R
Sbjct: 1093 QSQKREMREKMSEITKQLLESYDIE-DVRSRLSVEDLEHLNEDGELWFAYEGLKKATRVL 1151
Query: 1593 QRVVDSLQTSLDAETRSRN--------EVLRVKK--KMEGDLNEM----EIQLSHANRMA 1638
+ S + + E + N E+ ++K + E D+NE +L+ N M
Sbjct: 1152 ESHFQSQKDCYEKEIEALNFKVVHLSQEINHLQKLFREENDINESIRHEVTRLTSENMMI 1211
Query: 1639 AEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTE 1698
+ ++Q+ L+ +D +I+L N+ ++ +E +N L EE E T+
Sbjct: 1212 PDFKQQISELEKQKQDLEIRL------NEQAEKMKGKLEELSNQLHRSQEE-----EGTQ 1260
Query: 1699 RSRKLAEQELIETSERVQLLHSQNTSLINQKKKMESDLTQLQSEVEEAVQECRNAEEKAK 1758
R A+ E I T E+ +L+ Q+ + SD + Q E E V+ C +E ++
Sbjct: 1261 RKALEAQNE-IHTKEKEKLIDKI------QEMQEASDHLKKQFETESEVK-CNFRQEASR 1312
Query: 1759 KAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLE 1818
+ + +L++E D +R+ K ++ +K L + +A + G K+ +
Sbjct: 1313 LTLEN-----RDLEEELDMK---DRVIKKLQDQVKTLSKTIGKANDVHSSSGPKEYLGML 1364
Query: 1819 ARVRELEGEL 1828
RE E +L
Sbjct: 1365 QYKREDEAKL 1374
Score = 71.2 bits (173), Expect = 9e-12
Identities = 107/526 (20%), Positives = 220/526 (41%), Gaps = 57/526 (10%)
Query: 1448 QRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAY--EESLEHLETFKRENK 1505
+R + K+L E K + + +++ +S+ + ++ Y + + LE +EN
Sbjct: 847 RRRYRKMLEEHKAVILQKYARAWLARRRFQSIRRFVLNIQLTYRVQRLQKKLEDQNKENH 906
Query: 1506 NLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQSALEEAEA---SLEHEEGKILR 1562
L E+++ L L G +V +++K+ +LE ++ E+ + ++E + K+ +
Sbjct: 907 GLVEKLTSLAA-LRAG--DVEKIQKLEAELEKAATHRRNYEEKGKRYRDAVEEKLAKLQK 963
Query: 1563 AQLEFNQIKAEIERKLAEKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEG 1622
E K +I+ KL EK EE+++ N + L + E R R + ++K E
Sbjct: 964 HNSELETQKEQIQLKLQEKTEELKEKMDN---LTKQLFDDVQKEERQR---MLLEKSFEL 1017
Query: 1623 DLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLD----DAVRANDDLKENIAIVER 1678
+ E Q+ + + LQ L++ + D + R + +K I+ E+
Sbjct: 1018 KTQDYEKQIQSLKEEIKALKDEKMQLQHLVEGEHVTSDGLKAEVARLSKQVK-TISEFEK 1076
Query: 1679 RNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMESDLTQ 1738
LLQA+ ++ V+ +R + E+ + QLL S + + + +E DL
Sbjct: 1077 EIELLQAQKIDVEKHVQSQKREMREKMSEITK-----QLLESYDIEDVRSRLSVE-DLEH 1130
Query: 1739 LQSE----------------VEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLE 1782
L + +E Q ++ EK +A+ L +E + L
Sbjct: 1131 LNEDGELWFAYEGLKKATRVLESHFQSQKDCYEKEIEALN---FKVVHLSQEINHLQKLF 1187
Query: 1783 RMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELEGELEAEQKRNAESVKGM 1842
R + ++ ++I+ RL +E + + K+Q+ +LE + ++LE L + ++ ++ +
Sbjct: 1188 REENDINESIRHEVTRL-TSENMMIPDFKQQISELEKQKQDLEIRLNEQAEKMKGKLEEL 1246
Query: 1843 RKSERRIKE--------LTYQTEEDKKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTN 1894
R +E L Q E K +L D + ++Q K+Q E E
Sbjct: 1247 SNQLHRSQEEEGTQRKALEAQNEIHTKEKEKLIDKIQEMQEASDHLKKQFETESEVKCNF 1306
Query: 1895 LSKFRKVQHELDEAEERADIAESQVNKL----RAKSRDIGAKQKMH 1936
+ ++ E + EE D+ + + KL + S+ IG +H
Sbjct: 1307 RQEASRLTLENRDLEEELDMKDRVIKKLQDQVKTLSKTIGKANDVH 1352
>gi|122937345 myosin VB [Homo sapiens]
Length = 1848
Score = 583 bits (1502), Expect = e-166
Identities = 449/1508 (29%), Positives = 751/1508 (49%), Gaps = 176/1508 (11%)
Query: 35 TECFVPDDKEEFVKAKILS--REGGKVIA-----ETENGKTVTVKEDQV-LQQNPPKFDK 86
T ++PD E + A++ +EG K + ET + V+ +Q+ +NP
Sbjct: 11 TRVWIPDPDEVWRSAELTKDYKEGDKSLQLRLEDETILEYPIDVQRNQLPFLRNPDILVG 70
Query: 87 IEDMAMLTFLHEPAVLFNLKERYA-AWMIYTYSGLFCVTVNPYKWLPVYNAEVVAAYRGK 145
D+ L++LHEPAVL NLK R+ + IYTY G+ V +NPY+ LP+Y +V+ Y G+
Sbjct: 71 ENDLTALSYLHEPAVLHNLKVRFLESNHIYTYCGIVLVAINPYEQLPIYGQDVIYTYSGQ 130
Query: 146 KRSEAPPHIFSISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFASIAAIGDRG 205
+ PHIF++++ AY+ M D +NQSI+++GESGAGKTV+ K ++YFA++
Sbjct: 131 NMGDMDPHIFAVAEEAYKQMARDEKNQSIIVSGESGAGKTVSAKYAMRYFATVGG----- 185
Query: 206 KKDNANANKGTLEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIE 265
+A++ +E++++ ++P +EA GNAKT RNDNSSRFGK+I+I F + A++
Sbjct: 186 -----SASETNIEEKVLASSPIMEAIGNAKTTRNDNSSRFGKYIQIGFDKRYHIIGANMR 240
Query: 266 TYLLEKSRVIFQLKAERNYHIFYQILSNKK-PELLDMLLVTNNPYDYAFVSQG-EVSVAS 323
TYLLEKSRV+FQ ERNYHIFYQ+ + PE ++ L + D+ + SQG + S+
Sbjct: 241 TYLLEKSRVVFQADDERNYHIFYQLCAAAGLPEFKELALTSAE--DFFYTSQGGDTSIEG 298
Query: 324 IDDSEELMATDSAFDVLGFTSEEKAGVYKLTGAIMHYGNMKFKQKQREEQAEPDGTEDAD 383
+DD+E+ T AF +LG + ++K+ +I+H G++ Q +R+ + +D
Sbjct: 299 VDDAEDFEKTRQAFTLLGVKESHQMSIFKIIASILHLGSVAI-QAERDGDSCSISPQDVY 357
Query: 384 KSAY--LMGLNSADLLKGLCHPRVKVGNEYVTKGQSVQQVYYSIGALAKAVYEKMFNWMV 441
S + L+G+ + + LCH ++ +E K S+QQV + ALAK +Y ++F W+V
Sbjct: 358 LSNFCRLLGVEHSQMEHWLCHRKLVTTSETYVKTMSLQQVINARNALAKHIYAQLFGWIV 417
Query: 442 TRINATLETKQPRQYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMFVLEQEE 501
IN L T + FIGVLDI GFE F+ NSFEQ CIN+ NEKLQQ FN H+F LEQEE
Sbjct: 418 EHINKALHTSLKQHSFIGVLDIYGFETFEVNSFEQFCINYANEKLQQQFNSHVFKLEQEE 477
Query: 502 YKKEGIEWTFIDFGMDLQACIDLIEKPMGIMSILEEECMFPKATDMTFKAKLYDNHLGKS 561
Y KE I WT IDF D Q CIDLIE +GI+ +L+EEC PK TD + KLYD H S
Sbjct: 478 YMKEQIPWTLIDF-YDNQPCIDLIEAKLGILDLLDEECKVPKGTDQNWAQKLYDRH-SSS 535
Query: 562 NNFQKPRNIKGKQEAHFSLIHYAGTVDYNILGWLEKNKDPLNETVVALYQKSSLKLMATL 621
+FQKPR F ++H+A V+Y G+LEKN+D + E + + + S L+A L
Sbjct: 536 QHFQKPR----MSNTAFIIVHFADKVEYLSDGFLEKNRDTVYEEQINILKASKFPLVADL 591
Query: 622 FSS------YATADTGDSGK----SKGGKKKGSSFQ---TVSALHRENLNKLMTNLRTTH 668
F T G S K S K S+ + TV R +L+ LM L T
Sbjct: 592 FHDDKDPVPATTPGKGSSSKISVRSARPPMKVSNKEHKKTVGHQFRTSLHLLMETLNATT 651
Query: 669 PHFVRCIIPNERKAPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRILN 728
PH+VRCI PN+ K P D + QLR GVLE IRI G+P+R Y DF RYR+L
Sbjct: 652 PHYVRCIKPNDEKLPFHFDPKRAVQQLRACGVLETIRISAAGYPSRWAYHDFFNRYRVL- 710
Query: 729 PVAIPEGQFIDSRKGTEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLSRIIT 788
V E D + +L +L D ++++FG TK+FF+AG + LE++R ++
Sbjct: 711 -VKKRELANTDKKAICRSVLENLIKDPDKFQFGRTKIFFRAGQVAYLEKLRADKFRTATI 769
Query: 789 RMQAQARGQLMRIEFKKIVERRDALLVIQWNIRAFMG---------VKNWPWMKLYFKIK 839
+Q RG L ++++ ++ + A L +Q R + ++ ++ +++++
Sbjct: 770 MIQKTVRGWLQKVKYHRL---KGATLTLQRYCRGHLARRLAEHLRRIRAAVVLQKHYRMQ 826
Query: 840 PLLKSAETEKEMATMKEEFGR-------------------IKETLEKSEARRKELEEKMV 880
++ + + A + + F R I++ + ARR +
Sbjct: 827 RARQAYQRVRRAAVVIQAFTRAMFVRRTYRQVLMEHKATTIQKHVRGWMARRHFQRLRDA 886
Query: 881 SLLQEKNDLQLQVQAEQDNLNDAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTA 940
+++ + L+ + E L + L + + +E KV ++ ++ +E N E
Sbjct: 887 AIVIQCAFRMLKARRELKALRIEARSAEHLKRLNVGMENKVVQLQRKI---DEQNKEFKT 943
Query: 941 KKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKA 1000
+L S +++ L+ L V ++ E+ L EE+ L + + E+K
Sbjct: 944 LSEQLSVTTSTYTMEVERLKKEL--VHYQQSPGEDTSLRLQEEVESLRTELQRAHSERKI 1001
Query: 1001 LQEAHQQALDDLQ---VEEDKVNSLSK-SKVKLEQQV-----DDLEGSLEQEKKVRMDLE 1051
L++AH + D+L+ + ++ N+L K K +L Q+ D+ + +E ++ +LE
Sbjct: 1002 LEDAHSREKDELRKRVADLEQENALLKDEKEQLNNQILCQSKDEFAQNSVKENLMKKELE 1061
Query: 1052 RAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKK--------------EFDINQ---QNS 1094
+ + + +K + S ++ D L+ E + K+ E D N S
Sbjct: 1062 EERSRYQNLVK--EYSQLEQRYDNLRDEMTIIKQTPGHRRNPSNQSSLESDSNYPSISTS 1119
Query: 1095 KIED-----EQVLALQLQKKLKENQA--RIEELEEELEAERTARAKVEKLRSDLSRELEE 1147
+I D +QV + L+K + ++++ ELE ER +KL+ L + ++
Sbjct: 1120 EIGDTEDALQQVEEIGLEKAAMDMTVFLKLQKRVRELEQER------KKLQVQLEKREQQ 1173
Query: 1148 ISERLEEAGGATSVQIEMN----------KKREAEFQKMRRDLEE--ATLQHEATAAALR 1195
S++++ T + ++ N ++ E+E +K++ DL E + +AT
Sbjct: 1174 DSKKVQAEPPQTDIDLDPNADLAYNSLKRQELESENKKLKNDLNELRKAVADQATQNNSS 1233
Query: 1196 KKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLE 1255
DS + L ++ L+ ++LE K E + + S ++ + + ++
Sbjct: 1234 HGSPDSYSLL---LNQLKLAHEELEVRKEEVLILRTQIVSADQRRLAGRNAEPNINARSS 1290
Query: 1256 DQANEYRVKLEEAQRSLNDFTTQRAKLQ-----TENGELA---RQLEEKEALI-SQLTRG 1306
+E V E+A + + +K + E+GEL + L++ L+ +QL
Sbjct: 1291 WPNSEKHVDQEDAIEAYHGVCQTNSKTEDWGYLNEDGELGLAYQGLKQVARLLEAQLQAQ 1350
Query: 1307 KLSYTQQMEDLKRQL----EEEGKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRV 1362
L + +++E LK QL EE K + L LL + + E + E+ R+
Sbjct: 1351 SLEHEEEVEHLKAQLEALKEEMDKQQQTFCQTL--------LLSPEAQVEFGVQQEISRL 1402
Query: 1363 LSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQ---DAEEAVEAVNAKCSSLEKT 1419
T D + E+LE+ ++KL ++L+ + +EA A S E+
Sbjct: 1403 ------------TNENLDLKELVEKLEKNERKLKKQLKIYMKKAQDLEAAQALAQS-ERK 1449
Query: 1420 KHRLQNEI 1427
+H L ++
Sbjct: 1450 RHELNRQV 1457
Score = 67.8 bits (164), Expect = 1e-10
Identities = 126/642 (19%), Positives = 259/642 (40%), Gaps = 112/642 (17%)
Query: 1293 LEEKEALISQLTRGKLS--YTQQMEDLK-------RQLEEEGKAKNALAHALQSARHDCD 1343
+E K I + RG ++ + Q++ D R L+ + K AL +SA H
Sbjct: 860 MEHKATTIQKHVRGWMARRHFQRLRDAAIVIQCAFRMLKARRELK-ALRIEARSAEH--- 915
Query: 1344 LLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAE 1403
L R E + +LQR + + N E + T E+E KK+L Q
Sbjct: 916 LKRLNVGMENKV-VQLQRKIDEQNKEFKTLSEQLSVTTSTYTMEVERLKKELVHYQQ--- 971
Query: 1404 EAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAAL------------------- 1444
S E T RLQ E+E L +++R+++ L
Sbjct: 972 ----------SPGEDTSLRLQEEVESLRTELQRAHSERKILEDAHSREKDELRKRVADLE 1021
Query: 1445 -------DKKQRNFDKILAEWKQKYEES-------QSELESSQKEARSLSTELFKLKNAY 1490
D+K++ ++IL + K ++ ++ + ELE + ++L E +L+ Y
Sbjct: 1022 QENALLKDEKEQLNNQILCQSKDEFAQNSVKENLMKKELEEERSRYQNLVKEYSQLEQRY 1081
Query: 1491 EESLEHLETFK-----RENKNLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQSA 1545
+ + + K R N + Q + + + + E +Q VE++ L+ A
Sbjct: 1082 DNLRDEMTIIKQTPGHRRNPSNQSSLESDSNYPSISTSEIGDTEDALQQ--VEEIGLEKA 1139
Query: 1546 LEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHQRVVDSLQTSLDA 1605
+ L+ ++ ++ + E +++ ++E++ ++D + QA+ + L
Sbjct: 1140 AMDMTVFLKLQK-RVRELEQERKKLQVQLEKR-EQQDSKKVQAEPPQTDIDLDPNADLAY 1197
Query: 1606 ETRSRNEVLRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRA 1665
+ R E+ KK++ DLNE+ + A+ Q S + L+ A
Sbjct: 1198 NSLKRQELESENKKLKNDLNEL-------RKAVADQATQNNSSHGSPDSYSLLLNQLKLA 1250
Query: 1666 NDDL---KENIAIVERRNNLLQAELEEL---RAVVEQTERSRKLAEQELIETSERVQLLH 1719
+++L KE + I+ R ++ A+ L A RS ++ ++ + ++ H
Sbjct: 1251 HEELEVRKEEVLIL--RTQIVSADQRRLAGRNAEPNINARSSWPNSEKHVDQEDAIEAYH 1308
Query: 1720 SQNTSLINQKKKMESDLTQLQSEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDT-- 1777
+ Q D L + E + + ++ A+ + +A + A+ L+ E++
Sbjct: 1309 G-----VCQTNSKTEDWGYLNEDGELGL-AYQGLKQVAR--LLEAQLQAQSLEHEEEVEH 1360
Query: 1778 -SAHLERMKKNMEQTIKDLQHRLDEAEQIALKGG---------------KKQLQKLEARV 1821
A LE +K+ M++ + L + + ++ G K+ ++KLE
Sbjct: 1361 LKAQLEALKEEMDKQQQTFCQTLLLSPEAQVEFGVQQEISRLTNENLDLKELVEKLEKNE 1420
Query: 1822 RELEGELEAEQKR--NAESVKGMRKSERRIKELTYQTEEDKK 1861
R+L+ +L+ K+ + E+ + + +SER+ EL Q +K
Sbjct: 1421 RKLKKQLKIYMKKAQDLEAAQALAQSERKRHELNRQVTVQRK 1462
Score = 56.6 bits (135), Expect = 2e-07
Identities = 85/379 (22%), Positives = 169/379 (44%), Gaps = 63/379 (16%)
Query: 1530 KVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAK 1589
K R++L+ ++E +SA E K L +E N++ +++RK+ E+++E +
Sbjct: 898 KARRELKALRIEARSA----------EHLKRLNVGME-NKV-VQLQRKIDEQNKEFKTL- 944
Query: 1590 RNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQ 1649
S Q S+ T + EV R+KK++ + Q S + Q++V+SL+
Sbjct: 945 --------SEQLSVTTSTYTM-EVERLKKEL------VHYQQSPGEDTSLRLQEEVESLR 989
Query: 1650 SLLKDTQIQ---LDDA-VRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAE 1705
+ L+ + L+DA R D+L++ +A +E+ N LL+ E E+L + ++
Sbjct: 990 TELQRAHSERKILEDAHSREKDELRKRVADLEQENALLKDEKEQL------NNQILCQSK 1043
Query: 1706 QELIETSERVQLLHSQNTSLINQKKKMESDLTQLQSEVEEAVQECRNAEEKAKKAITDAA 1765
E + S + L+ + + +++ +L + S++E+ R+ K+
Sbjct: 1044 DEFAQNSVKENLMKKE----LEEERSRYQNLVKEYSQLEQRYDNLRDEMTIIKQTPGHRR 1099
Query: 1766 MMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQ---KLEARVR 1822
+ + E D++ I D + L + E+I L+ + KL+ RVR
Sbjct: 1100 NPSNQSSLESDSN-----YPSISTSEIGDTEDALQQVEEIGLEKAAMDMTVFLKLQKRVR 1154
Query: 1823 ELEGELEAEQKRNAESVKGMRKSERRIKELTYQTEEDKKNLLRLQDLVDKLQLKVKAYKR 1882
ELE E +K + K ++ ++++ QT+ DL L + KR
Sbjct: 1155 ELEQE---RKKLQVQLEKREQQDSKKVQAEPPQTD---------IDLDPNADLAYNSLKR 1202
Query: 1883 QAEEAE-EQANTNLSKFRK 1900
Q E+E ++ +L++ RK
Sbjct: 1203 QELESENKKLKNDLNELRK 1221
>gi|28416946 myosin 18A isoform a [Homo sapiens]
Length = 2054
Score = 515 bits (1327), Expect = e-145
Identities = 437/1710 (25%), Positives = 824/1710 (48%), Gaps = 239/1710 (13%)
Query: 47 VKAKILSREGGKVIAETEN-GKTVTVKEDQVLQQNPPKFDKIEDMAMLTFLHEPAVLFNL 105
+K++ L+ GKV + ++ G + V ED V + N P D++ED+A L +L+E +VL L
Sbjct: 366 LKSEELNLPEGKVRVKLDHDGAILDVDEDDVEKANAPSCDRLEDLASLVYLNESSVLHTL 425
Query: 106 KERYAAWMIYTYSGLFCVTVNPYKWLPVYNAEVVAAYRGKKRSEAPPHIFSISDNAYQYM 165
++RY A +++TY+G + + P VY+ +V+ ++G +R + PHI++++ AY+ M
Sbjct: 426 RQRYGASLLHTYAGPSLLVLGPRGAPAVYSEKVMHMFKGCRREDMAPHIYAVAQTAYRAM 485
Query: 166 LTDRENQSILITGESGAGKTVNTKRVIQYFASIAAIGDRGKKDNANANKGTLEDQIIQAN 225
L R++QSI++ G SG+GKT + + ++QY A+IA I + NK ++
Sbjct: 486 LMSRQDQSIILLGSSGSGKTTSCQHLVQYLATIAGI---------SGNKVFSVEKWQALY 536
Query: 226 PALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLEKSRVIFQLKAERNYH 285
LEAFGN+ T+ N N++RF + + + F G++ASA I+T LLEK RV + +E ++
Sbjct: 537 TLLEAFGNSPTIINGNATRFSQILSLDFDQAGQVASASIQTMLLEKLRVARRPASEATFN 596
Query: 286 IFYQILS----NKKPELLDMLLVTNNPYDYAFVSQGEVSVASIDDSEELMATDSAFDVLG 341
+FY +L+ + EL L NN + +++ E + +L A A VLG
Sbjct: 597 VFYYLLACGDGTLRTELHLNHLAENNVFGIVPLAKPEEKQKAAQQFSKLQA---AMKVLG 653
Query: 342 FTSEEKAGVYKLTGAIMHYGNMKFKQKQREEQAEPDGTED-ADKSAYLMGLNSADLLKGL 400
+ +E+ + + AI H G ++ E + + A K+AYL+G + +L +
Sbjct: 654 ISPDEQKACWFILAAIYHLGAAGATKEAAEAGRKQFARHEWAQKAAYLLGCSLEELSSAI 713
Query: 401 CHPRVKVGNEYVTKGQSVQQVYYSIG----------------ALAKAVYEKMFNWMVTRI 444
+ K G + + S +Q G +A +Y ++F +V+ +
Sbjct: 714 FKHQHKGGT--LQRSTSFRQGPEESGLGDGTGPKLSALECLEGMAAGLYSELFTLLVSLV 771
Query: 445 NATLETKQPRQYFIGVLDIAGFEIFDFN------SFEQLCINFTNEKLQQFFNHHMFVLE 498
N L++ Q + ++D GF+ + SFE+LC N+T ++LQ+ F+ FV E
Sbjct: 772 NRALKSSQHSLCSMMIVDTPGFQNPEQGGSARGASFEELCHNYTQDRLQRLFHERTFVQE 831
Query: 499 QEEYKKEGIEWTFIDFGM---DLQACIDLI------------EKPMGIMSILEEECMFPK 543
E YK+E IE F D D A +D ++ G++ +LEEE + P
Sbjct: 832 LERYKEENIELAFDDLEPPTDDSVAAVDQASHQSLVRSLARTDEARGLLWLLEEEALVPG 891
Query: 544 ATDMTFKAKLYDNHLGKSNNFQKPRN--IKGKQEAHFSLIHYAGT--VDYNILGWLEKNK 599
A++ T +L+ ++ G +K ++ + + HF L H GT V+YN+ GWL K
Sbjct: 892 ASEDTLLERLF-SYYGPQEGDKKGQSPLLHSSKPHHFLLGHSHGTNWVEYNVTGWLNYTK 950
Query: 600 -DPLNETVVALYQKSSLKLMATLFSSYATADTGDSGKSKGGKKKGS------------SF 646
+P + L Q S K+++ LF A + T SG S G + GS +F
Sbjct: 951 QNPATQNAPRLLQDSQKKIISNLFLGRAGSATVLSG-SIAGLEGGSQLALRRATSMRKTF 1009
Query: 647 QT-VSALHRENL--------NKLMTNLRTTHPHFVRCIIP-------------------- 677
T ++A+ +++L + L+ ++ + HFV C +P
Sbjct: 1010 TTGMAAVKKKSLCIQMKLQVDALIDTIKKSKLHFVHCFLPVAEGWAGEPRSASSRRVSSS 1069
Query: 678 NERKAPG---------VMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRILN 728
+E P +D PL+ QLR + +L+ +R+ R+G+P+ +++ +FR+R+ +L
Sbjct: 1070 SELDLPSGDHCEAGLLQLDVPLLRTQLRGSRLLDAMRMYRQGYPDHMVFSEFRRRFDVLA 1129
Query: 729 P-VAIPEGQ---FIDSRKGTEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLS 784
P + G+ +D R+ E+LL LD++ + G ++VFF+AG L LEE RDE+ S
Sbjct: 1130 PHLTKKHGRNYIVVDERRAVEELLECLDLEKSSCCMGLSRVFFRAGTLARLEEQRDEQTS 1189
Query: 785 RIITRMQAQARGQLMRIEFKKIVERRDALLVIQWNIRAFMGVKNWPWMKLYFKIKPLLKS 844
R +T QA RG L R FKK + A+ +Q NI+ GVK+WPW KL+ ++PL++
Sbjct: 1190 RNLTLFQAACRGYLARQHFKKRKIQDLAIRCVQKNIKKNKGVKDWPWWKLFTTVRPLIEV 1249
Query: 845 AETEKEMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLNDAE 904
+E+++ EE +++ LEK+E R EL L ++L ++ E++ A
Sbjct: 1250 QLSEEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESAS 1309
Query: 905 ERCDQLIKNKIQLEAKVKEMN---ERLEDEEEMNAELTAKKRKLEDECSELKKDIDD--- 958
+ D +++ E ++KE+ + L+ + E+ E+ + +L +E+ ++DD
Sbjct: 1310 QLLDAETAERLRAEKEMKELQTQYDALKKQMEV-MEMEVMEARL-IRAAEINGEVDDDDA 1367
Query: 959 ---LELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQVE 1015
L + +E T+ +++ E+ +++ + K+ L ++ L DLQ +
Sbjct: 1368 GGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQ------QNKRQL----ERRLGDLQAD 1417
Query: 1016 EDK----VNSLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIM-- 1069
++ + L K +L ++ D + LE ++ +LE+ +R+ + +L E
Sbjct: 1418 SEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQRE 1477
Query: 1070 DLENDKLQLE-EKLKKKEFDINQQNSKIEDEQVLALQLQKKLKENQARIEELEEELEAER 1128
L+ +KLQ E + L + F + QQ +E++ + +K+ +A ++++ + +
Sbjct: 1478 KLQREKLQREKDMLLAEAFSLKQQ---LEEKDMDIAGFTQKVVSLEAELQDISSQESKDE 1534
Query: 1129 TARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHE 1188
+ AKV+K DL ++++ E L+E G + LE+A L+ E
Sbjct: 1535 ASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQM------------------LEQAKLRLE 1576
Query: 1189 ATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLE 1248
+R+ H+ + E++ + +Q +K+ + +++L++ + +++++ K LE
Sbjct: 1577 MEMERMRQTHSKEMESRDEEV---EEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELE 1633
Query: 1249 KVSRTLEDQAN------EYRVK---------LEEAQRSLNDFTTQRAKLQTENGELARQL 1293
TL DQ N E R++ L +AQ L D A + E +L QL
Sbjct: 1634 GKLATLSDQVNRRDFESEKRLRKDLKRTKALLADAQLML-DHLKNSAPSKREIAQLKNQL 1692
Query: 1294 EEKEALISQLTRGKLSYTQQMEDLKRQLEEEGKAKNALAHALQSARHDCDLLREQYEEET 1353
EE E + + + + ++EDL Q+++ KAK AL L + + + ++ + EE+
Sbjct: 1693 EESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQ 1752
Query: 1354 EAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKC 1413
E ++ ++ K + VAQ A + LAQ + D + +E N +
Sbjct: 1753 E---DMNELMKKHKAAVAQ------------------ASRDLAQ-INDLQAQLEEANKEK 1790
Query: 1414 SSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQ 1473
L++ LQ+++E L E+S + + +++ + E + + E +++++ +
Sbjct: 1791 QELQEKLQALQSQVEFL----EQSMVDKSLVSRQEAK----IRELETRLEFERTQVKRLE 1842
Query: 1474 KEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGKNVHELEKVRK 1533
A L + KL ++ + K +NK LQ ++ D E++GE + E + +
Sbjct: 1843 SLASRLKENMEKLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAEASRKKH 1902
Query: 1534 QLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHQ 1593
+LE++ L++A + +A L+ A ++A IE ++ E DE ++
Sbjct: 1903 ELEMDLESLEAANQSLQADLK-------LAFKRIGDLQAAIEDEM-ESDE--------NE 1946
Query: 1594 RVVDSLQTSLDAETRSRNEVLRVKKKMEGD 1623
+++SLQ D T+ + K K+EGD
Sbjct: 1947 DLINSLQ---DMVTKYQKR----KNKLEGD 1969
Score = 199 bits (505), Expect = 3e-50
Identities = 184/818 (22%), Positives = 382/818 (46%), Gaps = 40/818 (4%)
Query: 1140 DLSRELEEISE--RLEEAG---GATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAAL 1194
D R +EE+ E LE++ G + V E Q+ + TL A L
Sbjct: 1144 DERRAVEELLECLDLEKSSCCMGLSRVFFRAGTLARLEEQRDEQTSRNLTLFQAACRGYL 1203
Query: 1195 RKKHADSVAELGEQIDNL--QRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSR 1252
++H +I +L + V++ ++K K + + + +I+ + + E++ R
Sbjct: 1204 ARQHFKK-----RKIQDLAIRCVQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQI-R 1257
Query: 1253 TLEDQANEYRVKLEEAQRSLNDFTTQRAKLQTENGELARQL-------EEKEALISQLTR 1305
+++ + R KLE+A++ N+ +L++ EL +L E L+ T
Sbjct: 1258 NKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDAETA 1317
Query: 1306 GKLSYTQQMEDLKRQLEEEGKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSK 1365
+L ++M++L+ Q + K + + AR ++ +A E + +
Sbjct: 1318 ERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWRLKYER 1377
Query: 1366 ANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQN 1425
A EV + + + + + E ++ K++L +RL D + E L+K RL
Sbjct: 1378 AVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTA 1437
Query: 1426 EIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFK 1485
E++D + +E L+KKQR FD L++ ++ + + + E Q+E L E F
Sbjct: 1438 ELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFS 1497
Query: 1486 LKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQSA 1545
LK EE + F ++ +L+ E+ D++ Q + ++ +++K + LE + + +
Sbjct: 1498 LKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEE 1557
Query: 1546 LEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHQRVVDSLQTSLDA 1605
L+E +++ E LR ++E +++ +++ +DEE+E+A+++ Q+ + ++ L+
Sbjct: 1558 LDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEE 1617
Query: 1606 ETRSRNEVLRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRA 1665
E + +VLR K+++EG L + Q+ NR E++K+ L+ LK T+ L DA
Sbjct: 1618 EYEDKQKVLREKRELEGKLATLSDQV---NRRDFESEKR---LRKDLKRTKALLADAQLM 1671
Query: 1666 NDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSL 1725
D LK N A +R L+ +LEE ++RK E E+ + ++ + T+L
Sbjct: 1672 LDHLK-NSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTAL 1730
Query: 1726 INQKKKMESDLTQLQSEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLE--- 1782
Q +++ + ++Q+ +EE ++ +K K A+ A + +L + D A LE
Sbjct: 1731 EEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQA---SRDLAQINDLQAQLEEAN 1787
Query: 1783 RMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELEGELEAEQKRNAESVKGM 1842
+ K+ +++ ++ LQ +++ EQ + K + + EA++RELE LE E+ + VK +
Sbjct: 1788 KEKQELQEKLQALQSQVEFLEQSMV--DKSLVSRQEAKIRELETRLEFERTQ----VKRL 1841
Query: 1843 RKSERRIKELTYQTEEDKKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQ 1902
R+KE + E++ + ++ + +++ R +E + ++ + +
Sbjct: 1842 ESLASRLKENMEKLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAEASRKK 1901
Query: 1903 HELDEAEERADIAESQVN-KLRAKSRDIGAKQKMHDEE 1939
HEL+ E + A + L+ + IG Q ++E
Sbjct: 1902 HELEMDLESLEAANQSLQADLKLAFKRIGDLQAAIEDE 1939
Score = 52.4 bits (124), Expect = 4e-06
Identities = 57/267 (21%), Positives = 118/267 (44%), Gaps = 52/267 (19%)
Query: 834 LYFKIKPLLKSAET-EKEMATMKEEFGRIKETLEKSEARRKELEEKMVSL-------LQE 885
L+ +I + K+ E++++ ++ E I+ LE+ + EL +K + L +
Sbjct: 1716 LHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQ 1775
Query: 886 KNDLQLQVQAEQDNLNDAEERCDQLIKNKIQL--------------EAKVKEMNERLEDE 931
NDLQ Q++ + +E+ Q ++++++ EAK++E+ RLE E
Sbjct: 1776 INDLQAQLEEANKEKQELQEKL-QALQSQVEFLEQSMVDKSLVSRQEAKIRELETRLEFE 1834
Query: 932 EEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEII 991
L + +L++ +L ++ D + +++ + ++++ EEM L
Sbjct: 1835 RTQVKRLESLASRLKENMEKLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGELARKE 1894
Query: 992 AKLTKEKKALQ------EAHQQALD-----------DLQV----------EEDKVNSLSK 1024
A+ +++K L+ EA Q+L DLQ ED +NSL
Sbjct: 1895 AEASRKKHELEMDLESLEAANQSLQADLKLAFKRIGDLQAAIEDEMESDENEDLINSLQD 1954
Query: 1025 SKVKLEQQVDDLEG--SLEQEKKVRMD 1049
K +++ + LEG ++ E + R+D
Sbjct: 1955 MVTKYQKRKNKLEGDSDVDSELEDRVD 1981
>gi|42794779 myosin 18A isoform b [Homo sapiens]
Length = 2039
Score = 513 bits (1322), Expect = e-145
Identities = 430/1685 (25%), Positives = 810/1685 (48%), Gaps = 224/1685 (13%)
Query: 47 VKAKILSREGGKVIAETEN-GKTVTVKEDQVLQQNPPKFDKIEDMAMLTFLHEPAVLFNL 105
+K++ L+ GKV + ++ G + V ED V + N P D++ED+A L +L+E +VL L
Sbjct: 366 LKSEELNLPEGKVRVKLDHDGAILDVDEDDVEKANAPSCDRLEDLASLVYLNESSVLHTL 425
Query: 106 KERYAAWMIYTYSGLFCVTVNPYKWLPVYNAEVVAAYRGKKRSEAPPHIFSISDNAYQYM 165
++RY A +++TY+G + + P VY+ +V+ ++G +R + PHI++++ AY+ M
Sbjct: 426 RQRYGASLLHTYAGPSLLVLGPRGAPAVYSEKVMHMFKGCRREDMAPHIYAVAQTAYRAM 485
Query: 166 LTDRENQSILITGESGAGKTVNTKRVIQYFASIAAIGDRGKKDNANANKGTLEDQIIQAN 225
L R++QSI++ G SG+GKT + + ++QY A+IA I + NK ++
Sbjct: 486 LMSRQDQSIILLGSSGSGKTTSCQHLVQYLATIAGI---------SGNKVFSVEKWQALY 536
Query: 226 PALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLEKSRVIFQLKAERNYH 285
LEAFGN+ T+ N N++RF + + + F G++ASA I+T LLEK RV + +E ++
Sbjct: 537 TLLEAFGNSPTIINGNATRFSQILSLDFDQAGQVASASIQTMLLEKLRVARRPASEATFN 596
Query: 286 IFYQILS----NKKPELLDMLLVTNNPYDYAFVSQGEVSVASIDDSEELMATDSAFDVLG 341
+FY +L+ + EL L NN + +++ E + +L A A VLG
Sbjct: 597 VFYYLLACGDGTLRTELHLNHLAENNVFGIVPLAKPEEKQKAAQQFSKLQA---AMKVLG 653
Query: 342 FTSEEKAGVYKLTGAIMHYGNMKFKQKQREEQAEPDGTED-ADKSAYLMGLNSADLLKGL 400
+ +E+ + + AI H G ++ E + + A K+AYL+G + +L +
Sbjct: 654 ISPDEQKACWFILAAIYHLGAAGATKEAAEAGRKQFARHEWAQKAAYLLGCSLEELSSAI 713
Query: 401 CHPRVKVGNEYVTKGQSVQQVYYSIG----------------ALAKAVYEKMFNWMVTRI 444
+ K G + + S +Q G +A +Y ++F +V+ +
Sbjct: 714 FKHQHKGGT--LQRSTSFRQGPEESGLGDGTGPKLSALECLEGMAAGLYSELFTLLVSLV 771
Query: 445 NATLETKQPRQYFIGVLDIAGFEIFDFN------SFEQLCINFTNEKLQQFFNHHMFVLE 498
N L++ Q + ++D GF+ + SFE+LC N+T ++LQ+ F+ FV E
Sbjct: 772 NRALKSSQHSLCSMMIVDTPGFQNPEQGGSARGASFEELCHNYTQDRLQRLFHERTFVQE 831
Query: 499 QEEYKKEGIEWTFIDFGM---DLQACIDLI------------EKPMGIMSILEEECMFPK 543
E YK+E IE F D D A +D ++ G++ +LEEE + P
Sbjct: 832 LERYKEENIELAFDDLEPPTDDSVAAVDQASHQSLVRSLARTDEARGLLWLLEEEALVPG 891
Query: 544 ATDMTFKAKLYDNHLGKSNNFQKPRN--IKGKQEAHFSLIHYAGT--VDYNILGWLEKNK 599
A++ T +L+ ++ G +K ++ + + HF L H GT V+YN+ GWL K
Sbjct: 892 ASEDTLLERLF-SYYGPQEGDKKGQSPLLHSSKPHHFLLGHSHGTNWVEYNVTGWLNYTK 950
Query: 600 -DPLNETVVALYQKSSLKLMATLFSSYATADTGDSGKSKGGKKKGS------------SF 646
+P + L Q S K+++ LF A + T SG S G + GS +F
Sbjct: 951 QNPATQNAPRLLQDSQKKIISNLFLGRAGSATVLSG-SIAGLEGGSQLALRRATSMRKTF 1009
Query: 647 QT-VSALHRENL--------NKLMTNLRTTHPHFVRCIIP-------------------- 677
T ++A+ +++L + L+ ++ + HFV C +P
Sbjct: 1010 TTGMAAVKKKSLCIQMKLQVDALIDTIKKSKLHFVHCFLPVAEGWAGEPRSASSRRVSSS 1069
Query: 678 NERKAPG---------VMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRILN 728
+E P +D PL+ QLR + +L+ +R+ R+G+P+ +++ +FR+R+ +L
Sbjct: 1070 SELDLPSGDHCEAGLLQLDVPLLRTQLRGSRLLDAMRMYRQGYPDHMVFSEFRRRFDVLA 1129
Query: 729 P-VAIPEGQ---FIDSRKGTEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLS 784
P + G+ +D R+ E+LL LD++ + G ++VFF+AG L LEE RDE+ S
Sbjct: 1130 PHLTKKHGRNYIVVDERRAVEELLECLDLEKSSCCMGLSRVFFRAGTLARLEEQRDEQTS 1189
Query: 785 RIITRMQAQARGQLMRIEFKKIVERRDALLVIQWNIRAFMGVKNWPWMKLYFKIKPLLKS 844
R +T QA RG L R FKK + A+ +Q NI+ GVK+WPW KL+ ++PL++
Sbjct: 1190 RNLTLFQAACRGYLARQHFKKRKIQDLAIRCVQKNIKKNKGVKDWPWWKLFTTVRPLIEV 1249
Query: 845 AETEKEMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLNDAE 904
+E+++ EE +++ LEK+E R EL L ++L ++ E++ A
Sbjct: 1250 QLSEEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESAS 1309
Query: 905 ERCDQLIKNKIQLEAKVKEMN---ERLEDEEEMNAELTAKKRKLEDECSELKKDIDD--- 958
+ D +++ E ++KE+ + L+ + E+ E+ + +L +E+ ++DD
Sbjct: 1310 QLLDAETAERLRAEKEMKELQTQYDALKKQMEV-MEMEVMEARL-IRAAEINGEVDDDDA 1367
Query: 959 ---LELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQVE 1015
L + +E T+ +++ E+ +++ + K+ L ++ L DLQ +
Sbjct: 1368 GGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQ------QNKRQL----ERRLGDLQAD 1417
Query: 1016 EDK----VNSLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIM-- 1069
++ + L K +L ++ D + LE ++ +LE+ +R+ + +L E
Sbjct: 1418 SEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQRE 1477
Query: 1070 DLENDKLQLE-EKLKKKEFDINQQNSKIEDEQVLALQLQKKLKENQARIEELEEELEAER 1128
L+ +KLQ E + L + F + QQ +E++ + +K+ +A ++++ + +
Sbjct: 1478 KLQREKLQREKDMLLAEAFSLKQQ---LEEKDMDIAGFTQKVVSLEAELQDISSQESKDE 1534
Query: 1129 TARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHE 1188
+ AKV+K DL ++++ E L+E G + LE+A L+ E
Sbjct: 1535 ASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQM------------------LEQAKLRLE 1576
Query: 1189 ATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLE 1248
+R+ H+ + E++ + +Q +K+ + +++L++ + +++++ K LE
Sbjct: 1577 MEMERMRQTHSKEMESRDEEV---EEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELE 1633
Query: 1249 KVSRTLEDQAN------EYRVK---------LEEAQRSLNDFTTQRAKLQTENGELARQL 1293
TL DQ N E R++ L +AQ L D A + E +L QL
Sbjct: 1634 GKLATLSDQVNRRDFESEKRLRKDLKRTKALLADAQLML-DHLKNSAPSKREIAQLKNQL 1692
Query: 1294 EEKEALISQLTRGKLSYTQQMEDLKRQLEEEGKAKNALAHALQSARHDCDLLREQYEEET 1353
EE E + + + + ++EDL Q+++ KAK AL L + + + ++ + EE+
Sbjct: 1693 EESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQ 1752
Query: 1354 EAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKC 1413
E ++ ++ K + VAQ A + LAQ + D + +E N +
Sbjct: 1753 E---DMNELMKKHKAAVAQ------------------ASRDLAQ-INDLQAQLEEANKEK 1790
Query: 1414 SSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQ 1473
L++ LQ+++E L E+S + + +++ + E + + E +++++ +
Sbjct: 1791 QELQEKLQALQSQVEFL----EQSMVDKSLVSRQEAK----IRELETRLEFERTQVKRLE 1842
Query: 1474 KEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGKNVHELEKVRK 1533
A L + KL ++ + K +NK LQ ++ D E++GE + E + +
Sbjct: 1843 SLASRLKENMEKLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAEASRKKH 1902
Query: 1534 QLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHQ 1593
+LE++ L++A + +A L+ A ++A IE ++ E DE +
Sbjct: 1903 ELEMDLESLEAANQSLQADLK-------LAFKRIGDLQAAIEDEM-ESDENEDLINSEGD 1954
Query: 1594 RVVDS 1598
VDS
Sbjct: 1955 SDVDS 1959
Score = 199 bits (505), Expect = 3e-50
Identities = 184/818 (22%), Positives = 382/818 (46%), Gaps = 40/818 (4%)
Query: 1140 DLSRELEEISE--RLEEAG---GATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAAL 1194
D R +EE+ E LE++ G + V E Q+ + TL A L
Sbjct: 1144 DERRAVEELLECLDLEKSSCCMGLSRVFFRAGTLARLEEQRDEQTSRNLTLFQAACRGYL 1203
Query: 1195 RKKHADSVAELGEQIDNL--QRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSR 1252
++H +I +L + V++ ++K K + + + +I+ + + E++ R
Sbjct: 1204 ARQHFKK-----RKIQDLAIRCVQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQI-R 1257
Query: 1253 TLEDQANEYRVKLEEAQRSLNDFTTQRAKLQTENGELARQL-------EEKEALISQLTR 1305
+++ + R KLE+A++ N+ +L++ EL +L E L+ T
Sbjct: 1258 NKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDAETA 1317
Query: 1306 GKLSYTQQMEDLKRQLEEEGKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSK 1365
+L ++M++L+ Q + K + + AR ++ +A E + +
Sbjct: 1318 ERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWRLKYER 1377
Query: 1366 ANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQN 1425
A EV + + + + + E ++ K++L +RL D + E L+K RL
Sbjct: 1378 AVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTA 1437
Query: 1426 EIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFK 1485
E++D + +E L+KKQR FD L++ ++ + + + E Q+E L E F
Sbjct: 1438 ELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFS 1497
Query: 1486 LKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQSA 1545
LK EE + F ++ +L+ E+ D++ Q + ++ +++K + LE + + +
Sbjct: 1498 LKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEE 1557
Query: 1546 LEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHQRVVDSLQTSLDA 1605
L+E +++ E LR ++E +++ +++ +DEE+E+A+++ Q+ + ++ L+
Sbjct: 1558 LDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEE 1617
Query: 1606 ETRSRNEVLRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRA 1665
E + +VLR K+++EG L + Q+ NR E++K+ L+ LK T+ L DA
Sbjct: 1618 EYEDKQKVLREKRELEGKLATLSDQV---NRRDFESEKR---LRKDLKRTKALLADAQLM 1671
Query: 1666 NDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSL 1725
D LK N A +R L+ +LEE ++RK E E+ + ++ + T+L
Sbjct: 1672 LDHLK-NSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTAL 1730
Query: 1726 INQKKKMESDLTQLQSEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLE--- 1782
Q +++ + ++Q+ +EE ++ +K K A+ A + +L + D A LE
Sbjct: 1731 EEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQA---SRDLAQINDLQAQLEEAN 1787
Query: 1783 RMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELEGELEAEQKRNAESVKGM 1842
+ K+ +++ ++ LQ +++ EQ + K + + EA++RELE LE E+ + VK +
Sbjct: 1788 KEKQELQEKLQALQSQVEFLEQSMV--DKSLVSRQEAKIRELETRLEFERTQ----VKRL 1841
Query: 1843 RKSERRIKELTYQTEEDKKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQ 1902
R+KE + E++ + ++ + +++ R +E + ++ + +
Sbjct: 1842 ESLASRLKENMEKLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAEASRKK 1901
Query: 1903 HELDEAEERADIAESQVN-KLRAKSRDIGAKQKMHDEE 1939
HEL+ E + A + L+ + IG Q ++E
Sbjct: 1902 HELEMDLESLEAANQSLQADLKLAFKRIGDLQAAIEDE 1939
Score = 80.5 bits (197), Expect = 1e-14
Identities = 98/439 (22%), Positives = 195/439 (44%), Gaps = 28/439 (6%)
Query: 721 RQRYRILNPVAIPEGQFIDSRKGTEKLLSS----LDIDHNQYKFGHTKVFFKAGLLGLLE 776
+++ R L + + +D + GT ++L L+++ + + H+K +E
Sbjct: 1541 KKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRD--EEVE 1598
Query: 777 EMRD---ERLSRIITRMQAQARGQLMRIEFKKIVERRDALLVIQWNIRAFMGVKNWPWMK 833
E R ++L ++ +++ + + + K+ +E + A L Q N R F K K
Sbjct: 1599 EARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVNRRDFESEKRL--RK 1656
Query: 834 LYFKIKPLLKSAETE----KEMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDL 889
+ K LL A+ K A K E ++K LE+SE + ++ E DL
Sbjct: 1657 DLKRTKALLADAQLMLDHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDL 1716
Query: 890 QLQVQAEQDNLNDAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDEC 949
LQ+ EE+ +L + K +++ +++E D+E+MN EL K + +
Sbjct: 1717 HLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEE------DQEDMN-ELMKKHKAAVAQA 1769
Query: 950 SELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQAL 1009
S I+DL+ L + KEK + K++ L ++ L++ + + K + QEA + L
Sbjct: 1770 SRDLAQINDLQAQLEEANKEKQELQEKLQALQSQVEFLEQ--SMVDKSLVSRQEAKIREL 1827
Query: 1010 DD-LQVEEDKVNSLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESI 1068
+ L+ E +V L +L++ ++ L +Q + ++L+ L+ T+E +
Sbjct: 1828 ETRLEFERTQVKRLESLASRLKENMEKLTEERDQRIAAENREKEQNKRLQRQLRDTKEEM 1887
Query: 1069 MDLENDKLQLEEKLKKKEFDINQQNSKIEDEQVLALQLQKKLKENQARIEELEEELEAER 1128
+L + + K + E D+ + + Q K++ + QA IE+ E E E
Sbjct: 1888 GELARKEAEASRKKHELEMDLESLEAANQSLQADLKLAFKRIGDLQAAIEDEMESDENED 1947
Query: 1129 TARAKVEKLRSDLSRELEE 1147
++ + SD+ ELE+
Sbjct: 1948 LINSEGD---SDVDSELED 1963
>gi|154354979 myosin X [Homo sapiens]
Length = 2058
Score = 483 bits (1243), Expect = e-136
Identities = 322/1026 (31%), Positives = 549/1026 (53%), Gaps = 55/1026 (5%)
Query: 57 GKVIAETENGKTVTVKEDQVLQQ-----NPPKFDKIEDMAMLTFLHEPAVLFNLKERYAA 111
G V+ T+ G+ T K+ + Q +P + ++DMA LT LH ++++NL +RY
Sbjct: 30 GIVVFRTDYGQVFTYKQSTITHQKVTAMHPTNEEGVDDMASLTELHGGSIMYNLFQRYKR 89
Query: 112 WMIYTYSGLFCVTVNPYKWLP-VYNAEVVAAYRGKKRSEAPPHIFSISDNAYQYMLTDRE 170
IYTY G +VNPY+ + +Y + Y + E PPHIF+I++ Y+ + +
Sbjct: 90 NQIYTYIGSILASVNPYQPIAGLYEPATMEQYSRRHLGELPPHIFAIANECYRCLWKRHD 149
Query: 171 NQSILITGESGAGKTVNTKRVIQYFASIAAIGDRGKKDNANANKGTLEDQIIQANPALEA 230
NQ ILI+GESGAGKT +TK ++++ ++ I + + + +E I++++P +EA
Sbjct: 150 NQCILISGESGAGKTESTKLILKF---LSVISQQSLELSLKEKTSCVERAILESSPIMEA 206
Query: 231 FGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLEKSRVIFQLKAERNYHIFYQI 290
FGNAKTV N+NSSRFGKF++++ G + I YLLEK+RV+ Q ERNYHIFY +
Sbjct: 207 FGNAKTVYNNNSSRFGKFVQLNICQKGNIQGGRIVDYLLEKNRVVRQNPGERNYHIFYAL 266
Query: 291 LSNKKPELLDMLLVTNNPYDYAFVSQ-GEVSVASIDDSEELMATDSAFDVLGFTSEEKAG 349
L+ + E + + + P +Y +++Q G V +I D E +A DV+ F+ EE
Sbjct: 267 LAGLEHEEREEFYL-STPENYHYLNQSGCVEDKTISDQESFREVITAMDVMQFSKEEVRE 325
Query: 350 VYKLTGAIMHYGNMKFKQKQREEQAEPDGTEDADKSAYLMGLNSADLLKGLCHPRVKVGN 409
V +L I+H GN++F A+ +SA L+GL+ L L + +
Sbjct: 326 VSRLLAGILHLGNIEF---ITAGGAQVSFKTALGRSAELLGLDPTQLTDALTQRSMFLRG 382
Query: 410 EYVTKGQSVQQVYYSIGALAKAVYEKMFNWMVTRINATLETKQPRQYFIGVLDIAGFEIF 469
E + +VQQ S +LA A+Y F W++ +IN+ ++ + + IG+LDI GFE F
Sbjct: 383 EEILTPLNVQQAVDSRDSLAMALYACCFEWVIKKINSRIKGNEDFK-SIGILDIFGFENF 441
Query: 470 DFNSFEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLQACIDLIEKPM 529
+ N FEQ IN+ NEKLQ++FN H+F LEQ EY +EG+ W ID+ +D C+DLIEK +
Sbjct: 442 EVNHFEQFNINYANEKLQEYFNKHIFSLEQLEYSREGLVWEDIDW-IDNGECLDLIEKKL 500
Query: 530 GIMSILEEECMFPKATDMTFKAKLYDNHLGKSNNFQKPRNIKGKQEAHFSLIHYAGTVDY 589
G+++++ EE FP+ATD T KL+ H ++ + KPR +F + HYAG V Y
Sbjct: 501 GLLALINEESHFPQATDSTLLEKLHSQH-ANNHFYVKPRVAVN----NFGVKHYAGEVQY 555
Query: 590 NILGWLEKNKDPLNETVVALYQKSSLKLMATLFSSYATADTGDSGKSKGGKKKGSSFQTV 649
++ G LEKN+D + ++ L ++S + LF ++ + D+ K ++ TV
Sbjct: 556 DVRGILEKNRDTFRDDLLNLLRESRFDFIYDLFEHVSSRNNQDTLKCGSKHRR----PTV 611
Query: 650 SALHRENLNKLMTNLRTTHPHFVRCIIPNERKAPGVMDNPLVMHQLRCNGVLEGIRICRK 709
S+ +++L+ LM L +++P FVRCI PN +K P D +V++QLR +G+LE +RI +
Sbjct: 612 SSQFKDSLHSLMATLSSSNPFFVRCIKPNMQKMPDQFDQAVVLNQLRYSGMLETVRIRKA 671
Query: 710 GFPNRILYGDFRQRYRIL-NPVAIPEGQFIDSRKGTEKLLSSLDIDHNQYKFGHTKVFFK 768
G+ R + DF +RY++L +A+PE D R LL D +++++ G TKVF +
Sbjct: 672 GYAVRRPFQDFYKRYKVLMRNLALPE----DVRGKCTSLLQLYDASNSEWQLGKTKVFLR 727
Query: 769 AGLLGLLEEMRDERLSRIITRMQAQARGQLMRIEFKKIVERRDALLVIQWNIRAFMGVKN 828
L LE+ R+E +S ++A G L R +++K++ +++IQ N RAF+ +
Sbjct: 728 ESLEQKLEKRREEEVSHAAMVIRAHVLGFLARKQYRKVLY---CVVIIQKNYRAFLLRRR 784
Query: 829 WPWMKLYFKIKPLLKSAETEKEMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKND 888
+ L+ K ++ + ++A + + A ++E EEK +EK
Sbjct: 785 F----LHLKKAAIVFQKQLRGQIA---------RRVYRQLLAEKREQEEKKKQEEEEKKK 831
Query: 889 LQLQVQAEQDNLNDAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAEL-TAKKRKLED 947
+ + + + +AE R Q + + Q E + + +++ E E+ EL K+ K +
Sbjct: 832 REEEERERERERREAELRAQQEEETRKQQELEALQKSQK---EAELTRELEKQKENKQVE 888
Query: 948 ECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQ 1007
E L+K+I+DL+ K ++E TE ++ L E D+ + +L +E + +
Sbjct: 889 EILRLEKEIEDLQ--RMKEQQELSLTEASLQKLQERR---DQELRRLEEEACRAAQEFLE 943
Query: 1008 ALDDLQVEEDKVNSLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQES 1067
+L+ +++E N V E + E + E++ + +++ + ++
Sbjct: 944 SLNFDEIDECVRNIERSLSVGSEFSSELAESACEEKPNFNFSQPYPEEEVDEGFEADDDA 1003
Query: 1068 IMDLEN 1073
D N
Sbjct: 1004 FKDSPN 1009
Score = 53.1 bits (126), Expect = 3e-06
Identities = 68/303 (22%), Positives = 126/303 (41%), Gaps = 37/303 (12%)
Query: 1213 QRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRSL 1272
+ ++QKLEK + E S+ +I+A + Q + + Q++
Sbjct: 728 ESLEQKLEKRREE-------EVSHAAMVIRAHV----LGFLARKQYRKVLYCVVIIQKNY 776
Query: 1273 NDFTTQRAKLQTENGELARQLEEKEALISQLTRGKLSYTQQMEDLKRQLEEEGKAKNALA 1332
F +R L + + Q + + + ++ R L+ ++ E+ K+Q EEE K +
Sbjct: 777 RAFLLRRRFLHLKKAAIVFQKQLRGQIARRVYRQLLAEKREQEEKKKQEEEEKKKREEEE 836
Query: 1333 HALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAK 1392
+ R + + LR Q EEET + EL+ L K+ E R + ++ EE+ +
Sbjct: 837 RERERERREAE-LRAQQEEETRKQQELE-ALQKSQKEAELTRELEKQKENKQVEEILRLE 894
Query: 1393 KKL--AQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRN 1450
K++ QR+++ +E ++ +SL+K + R E+ L E AA + N
Sbjct: 895 KEIEDLQRMKEQQE----LSLTEASLQKLQERRDQELRRL----EEEACRAAQEFLESLN 946
Query: 1451 FDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEE 1510
FD+I +E +E S S+EL E + E F +EE
Sbjct: 947 FDEI--------DECVRNIERSLSVGSEFSSEL------AESACEEKPNFNFSQPYPEEE 992
Query: 1511 ISD 1513
+ +
Sbjct: 993 VDE 995
Score = 45.8 bits (107), Expect = 4e-04
Identities = 49/193 (25%), Positives = 85/193 (44%), Gaps = 21/193 (10%)
Query: 1022 LSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEEK 1081
L K+ + ++Q L G + ++V L KR+ E K +E E ++ + E +
Sbjct: 788 LKKAAIVFQKQ---LRGQIA--RRVYRQLLAEKREQEEKKKQEEEEKKKREEEERERERE 842
Query: 1082 LKKKEFDINQQNSKIEDEQVLALQLQKKLKENQARIEELEEELEAERTARAKVEKLRSDL 1141
++ E Q+ + +++ ALQ +K E +E+ +E + E R +EK DL
Sbjct: 843 RREAELRAQQEEETRKQQELEALQKSQKEAELTRELEKQKENKQVEEILR--LEKEIEDL 900
Query: 1142 SRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADS 1201
R E+ L EA + K +E RRD E L+ EA AA + +
Sbjct: 901 QRMKEQQELSLTEA--------SLQKLQE------RRDQELRRLEEEACRAAQEFLESLN 946
Query: 1202 VAELGEQIDNLQR 1214
E+ E + N++R
Sbjct: 947 FDEIDECVRNIER 959
Score = 42.7 bits (99), Expect = 0.003
Identities = 72/362 (19%), Positives = 145/362 (40%), Gaps = 68/362 (18%)
Query: 1078 LEEKLKKKEFDINQQNSKIEDEQVLALQLQKK----------LKENQARIEELEEELEAE 1127
LE+KL+K+ + + + VL +K+ +++N L +
Sbjct: 730 LEQKLEKRREEEVSHAAMVIRAHVLGFLARKQYRKVLYCVVIIQKNYRAFLLRRRFLHLK 789
Query: 1128 RTARAKVEKLRSDLSREL--EEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATL 1185
+ A ++LR ++R + + ++E+ E+ KK++ E +K +R+ EE
Sbjct: 790 KAAIVFQKQLRGQIARRVYRQLLAEKREQE----------EKKKQEEEEKKKREEEERER 839
Query: 1186 QHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKL--ELDDVTSN--MEQII 1241
+ E A LR + + + Q+ + L+K + E +L EL+ N +E+I+
Sbjct: 840 ERERREAELRAQQEEETRK--------QQELEALQKSQKEAELTRELEKQKENKQVEEIL 891
Query: 1242 KAKANLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQTENGELARQLEEKEALIS 1301
+ + +E + R E Q + SL + + Q KLQ + R+LEE+ +
Sbjct: 892 RLEKEIEDLQRMKEQQ-----------ELSLTEASLQ--KLQERRDQELRRLEEEACRAA 938
Query: 1302 QLTRGKLSYTQQME---DLKRQLEEEGKAKNALAHALQSARHDCDLLREQYEEETEAKAE 1358
Q L++ + E +++R L + + LA + + + + + EEE + E
Sbjct: 939 QEFLESLNFDEIDECVRNIERSLSVGSEFSSELAESACEEKPNFNFSQPYPEEEVDEGFE 998
Query: 1359 L------------------QRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQ 1400
QR S+ + Y D + T ++ LA +Q
Sbjct: 999 ADDDAFKDSPNPSEHGHSDQRTSGIRTSDDSSEEDPYMNDTVVPTSPSADSTVLLAPSVQ 1058
Query: 1401 DA 1402
D+
Sbjct: 1059 DS 1060
Score = 38.5 bits (88), Expect = 0.065
Identities = 27/113 (23%), Positives = 56/113 (49%), Gaps = 9/113 (7%)
Query: 1818 EARVRELEGELEAEQKRNAESVKGMRKSERRIKELTYQTEEDKKNLLRLQDLVDKLQLKV 1877
E R +E + + E E+K+ E + R+ ERR EL Q EE+ R Q ++ LQ
Sbjct: 814 EKREQEEKKKQEEEEKKKREEEERERERERREAELRAQQEEE----TRKQQELEALQKSQ 869
Query: 1878 KAYKRQAEEAEEQANTNLSKFRKVQHELDE-----AEERADIAESQVNKLRAK 1925
K + E +++ N + + +++ E+++ ++ + E+ + KL+ +
Sbjct: 870 KEAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQELSLTEASLQKLQER 922
Score = 37.4 bits (85), Expect = 0.14
Identities = 54/230 (23%), Positives = 108/230 (46%), Gaps = 25/230 (10%)
Query: 1688 EELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMESDLTQLQSEVEEAV 1747
++LR + + + LAE+ E ++ + + ++++ E +L+++ EE
Sbjct: 797 KQLRGQIARRVYRQLLAEKREQEEKKKQEEEEKKKREEEERERERERREAELRAQQEEET 856
Query: 1748 QECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIAL 1807
+ + E +A + A + EL+K+++ E ++ +E+ I+DLQ R+ E ++++L
Sbjct: 857 R--KQQELEALQKSQKEAELTRELEKQKENKQVEEILR--LEKEIEDLQ-RMKEQQELSL 911
Query: 1808 KGGKKQLQKLEARVRELEGELEAEQKRNAESVKGMRKSERRIKELTY-QTEEDKKNLLRL 1866
+ LQKL+ R + LE E R A+ ++ L + + +E +N+ R
Sbjct: 912 T--EASLQKLQERRDQELRRLEEEACRAAQEF---------LESLNFDEIDECVRNIER- 959
Query: 1867 QDLVDKLQLKVKAYKRQAEEA-EEQANTNLSKFRKVQHELDEAEERADIA 1915
L + + AE A EE+ N N S+ + E+DE E D A
Sbjct: 960 -----SLSVGSEFSSELAESACEEKPNFNFSQ-PYPEEEVDEGFEADDDA 1003
Score = 37.0 bits (84), Expect = 0.19
Identities = 33/125 (26%), Positives = 59/125 (47%), Gaps = 13/125 (10%)
Query: 1445 DKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKREN 1504
+KK+R + E +++ E ++EL + Q+E EL L+ + +E+ E K++
Sbjct: 828 EKKKREEE----ERERERERREAELRAQQEEETRKQQELEALQKSQKEAELTRELEKQKE 883
Query: 1505 KNLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLE--LQSALEEAEASLEHEEGKILR 1562
EEI L K + +L+++++Q E+ E LQ E + L E + R
Sbjct: 884 NKQVEEILRLE-------KEIEDLQRMKEQQELSLTEASLQKLQERRDQELRRLEEEACR 936
Query: 1563 AQLEF 1567
A EF
Sbjct: 937 AAQEF 941
Score = 36.2 bits (82), Expect = 0.32
Identities = 45/186 (24%), Positives = 81/186 (43%), Gaps = 33/186 (17%)
Query: 1446 KKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENK 1505
++Q K E K+K EE + E E ++EA +L+ EE + + K
Sbjct: 816 REQEEKKKQEEEEKKKREEEERERERERREA--------ELRAQQEEETRKQQELEALQK 867
Query: 1506 NLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQL 1565
+ +E ++LT +L + +N E +R + E+E +LQ E+ E SL
Sbjct: 868 SQKE--AELTRELEKQKENKQVEEILRLEKEIE--DLQRMKEQQELSL------------ 911
Query: 1566 EFNQIKAEIERKLAEKDEEM----EQAKRNHQRVVDSLQ-TSLDAETRSRNEVLRVKKKM 1620
+A +++ +D+E+ E+A R Q ++SL +D R+ L V +
Sbjct: 912 ----TEASLQKLQERRDQELRRLEEEACRAAQEFLESLNFDEIDECVRNIERSLSVGSEF 967
Query: 1621 EGDLNE 1626
+L E
Sbjct: 968 SSELAE 973
Score = 35.0 bits (79), Expect = 0.71
Identities = 43/184 (23%), Positives = 80/184 (43%), Gaps = 16/184 (8%)
Query: 1530 KVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAK 1589
+V +QL EK E +E + E EE K + E + + E ER+ AE + E+
Sbjct: 806 RVYRQLLAEKRE-----QEEKKKQEEEEKK----KREEEERERERERREAELRAQQEEET 856
Query: 1590 RNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQ 1649
R Q + ++ +AE E + K++E ++ +E ++ RM + Q+++ +
Sbjct: 857 RKQQELEALQKSQKEAELTRELEKQKENKQVE-EILRLEKEIEDLQRM--KEQQELSLTE 913
Query: 1650 SLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELI 1709
+ L+ Q + D +R E A + L +E+ V ERS + +
Sbjct: 914 ASLQKLQERRDQELRR----LEEEACRAAQEFLESLNFDEIDECVRNIERSLSVGSEFSS 969
Query: 1710 ETSE 1713
E +E
Sbjct: 970 ELAE 973
>gi|189083802 myosin VIIA isoform 2 [Homo sapiens]
Length = 2175
Score = 471 bits (1213), Expect = e-132
Identities = 327/923 (35%), Positives = 487/923 (52%), Gaps = 71/923 (7%)
Query: 80 NPPKFDKIEDMAMLTFLHEPAVLFNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNAEVV 139
+P +EDM L L+E +L NL RY +IYTY+G V VNPY+ L +Y+ E +
Sbjct: 60 HPTSVHGVEDMIRLGDLNEAGILRNLLIRYRDHLIYTYTGSILVAVNPYQLLSIYSPEHI 119
Query: 140 AAYRGKKRSEAPPHIFSISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFASIA 199
Y KK E PPHIF+I+DN Y M + +Q +I+GESGAGKT +TK ++Q+ A+I+
Sbjct: 120 RQYTNKKIGEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFLAAIS 179
Query: 200 AIGDRGKKDNANANKGTLEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKL 259
+E Q+++A P LEAFGNAKT+RNDNSSRFGK+I IHF G +
Sbjct: 180 G------------QHSWIEQQVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKRGAI 227
Query: 260 ASADIETYLLEKSRVIFQLKAERNYHIFYQILSNKKPELLDMLLVTNNPYDYAFVSQGE- 318
A IE YLLEKSRV Q ERNYH+FY +L + L + DY +++ G
Sbjct: 228 EGAKIEQYLLEKSRVCRQALDERNYHVFYCMLEGMSEDQKKKLGL-GQASDYNYLAMGNC 286
Query: 319 VSVASIDDSEELMATDSAFDVLGFTSEEKAGVYKLTGAIMHYGNMKFKQKQRE--EQAEP 376
++ DS+E SA VL FT E + KL AI+H GN++++ + E + E
Sbjct: 287 ITCEGRVDSQEYANIRSAMKVLMFTDTENWEISKLLAAILHLGNLQYEARTFENLDACEV 346
Query: 377 DGTEDADKSAYLMGLNSADLLKGLCHPRVKVGNEYVTKGQSVQQVYYSIGALAKAVYEKM 436
+ +A L+ +N DL+ L + E V+ S +Q A K +Y ++
Sbjct: 347 LFSPSLATAASLLEVNPPDLMSCLTSRTLITRGETVSTPLSREQALDVRDAFVKGIYGRL 406
Query: 437 FNWMVTRINATL------ETKQPRQYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFF 490
F W+V +INA + + K R+ IG+LDI GFE F NSFEQLCINF NE LQQFF
Sbjct: 407 FVWIVDKINAAIYKPPSQDVKNSRRS-IGLLDIFGFENFAVNSFEQLCINFANEHLQQFF 465
Query: 491 NHHMFVLEQEEYKKEGIEWTFIDFGMDLQACIDLI-EKPMGIMSILEEECMFPKATDMTF 549
H+F LEQEEY E I+W I+F D Q +D+I KPM I+S+++EE FPK TD T
Sbjct: 466 VRHVFKLEQEEYDLESIDWLHIEF-TDNQDALDMIANKPMNIISLIDEESKFPKGTDTTM 524
Query: 550 KAKLYDNHLGKSN-NFQKPRNIKGKQEAHFSLIHYAGTVDYNILGWLEKNKDPLNETVVA 608
KL H K N N+ P+N E F + H+AG V Y G+LEKN+D L+ ++
Sbjct: 525 LHKLNSQH--KLNANYIPPKN---NHETQFGINHFAGIVYYETQGFLEKNRDTLHGDIIQ 579
Query: 609 LYQKSSLKLMATLFSSYATADTGDSGKSKGGKKKGSSFQTVSALHRENLNKLMTNLRTTH 668
L S K + +F + G + T+S+ + +L LM L
Sbjct: 580 LVHSSRNKFIKQIFQADVAM----------GAETRKRSPTLSSQFKRSLELLMRTLGACQ 629
Query: 669 PHFVRCIIPNERKAPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRILN 728
P FVRCI PNE K P + D L + QLR +G++E IRI R G+P R + +F +RYR+L
Sbjct: 630 PFFVRCIKPNEFKKPMLFDRHLCVRQLRYSGMMETIRIRRAGYPIRYSFVEFVERYRVLL 689
Query: 729 PVAIPEGQFIDSRKGTEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLSRIIT 788
P P + D R +++ ++ H+ ++ G TK+F K LLE RD+ ++ +
Sbjct: 690 PGVKPAYKQGDLRGTCQRMAEAVLGTHDDWQIGKTKIFLKDHHDMLLEVERDKAITDRVI 749
Query: 789 RMQAQARGQLMRIEFKKIVERRDALLVIQWNIRAFMGVKNWPWMKL-YFKIKPLLKSAET 847
+Q RG R F K+ ++A +IQ + R KN+ M+L + +++ L +S +
Sbjct: 750 LLQKVIRGFKDRSNFLKL---KNAATLIQRHWRGHNCRKNYGLMRLGFLRLQALHRSRKL 806
Query: 848 EKEMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLNDAEERC 907
++ ++ + + ++ RK ++ ++ L VQA + R
Sbjct: 807 HQQYRLARQRIIQFQARC-RAYLVRKAFRHRLWAV--------LTVQAYARGM--IARRL 855
Query: 908 DQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKK------RKLEDECSELKKDIDDLEL 961
Q ++ + + ++M RL +EE++ E++AKK RK ++ ++L ++ + EL
Sbjct: 856 HQRLRAEYLWRLEAEKM--RLAEEEKLRKEMSAKKAKEEAERKHQERLAQLAREDAEREL 913
Query: 962 TLAKVEKEKHATENKVKNLTEEM 984
KEK A K K L E+M
Sbjct: 914 ------KEKEAARRK-KELLEQM 929
Score = 33.9 bits (76), Expect = 1.6
Identities = 24/76 (31%), Positives = 38/76 (50%), Gaps = 8/76 (10%)
Query: 1527 ELEKVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEME 1586
E EK+RK++ +K A EEAE + ++ R E + E R+ E E+ME
Sbjct: 876 EEEKLRKEMSAKK-----AKEEAERKHQERLAQLAREDAERELKEKEAARRKKELLEQME 930
Query: 1587 QAKR---NHQRVVDSL 1599
+A+ NH +VD +
Sbjct: 931 RARHEPVNHSDMVDKM 946
>gi|189083800 myosin VIIA isoform 3 [Homo sapiens]
Length = 1204
Score = 471 bits (1213), Expect = e-132
Identities = 327/923 (35%), Positives = 487/923 (52%), Gaps = 71/923 (7%)
Query: 80 NPPKFDKIEDMAMLTFLHEPAVLFNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNAEVV 139
+P +EDM L L+E +L NL RY +IYTY+G V VNPY+ L +Y+ E +
Sbjct: 60 HPTSVHGVEDMIRLGDLNEAGILRNLLIRYRDHLIYTYTGSILVAVNPYQLLSIYSPEHI 119
Query: 140 AAYRGKKRSEAPPHIFSISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFASIA 199
Y KK E PPHIF+I+DN Y M + +Q +I+GESGAGKT +TK ++Q+ A+I+
Sbjct: 120 RQYTNKKIGEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFLAAIS 179
Query: 200 AIGDRGKKDNANANKGTLEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKL 259
+E Q+++A P LEAFGNAKT+RNDNSSRFGK+I IHF G +
Sbjct: 180 G------------QHSWIEQQVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKRGAI 227
Query: 260 ASADIETYLLEKSRVIFQLKAERNYHIFYQILSNKKPELLDMLLVTNNPYDYAFVSQGE- 318
A IE YLLEKSRV Q ERNYH+FY +L + L + DY +++ G
Sbjct: 228 EGAKIEQYLLEKSRVCRQALDERNYHVFYCMLEGMSEDQKKKLGL-GQASDYNYLAMGNC 286
Query: 319 VSVASIDDSEELMATDSAFDVLGFTSEEKAGVYKLTGAIMHYGNMKFKQKQRE--EQAEP 376
++ DS+E SA VL FT E + KL AI+H GN++++ + E + E
Sbjct: 287 ITCEGRVDSQEYANIRSAMKVLMFTDTENWEISKLLAAILHLGNLQYEARTFENLDACEV 346
Query: 377 DGTEDADKSAYLMGLNSADLLKGLCHPRVKVGNEYVTKGQSVQQVYYSIGALAKAVYEKM 436
+ +A L+ +N DL+ L + E V+ S +Q A K +Y ++
Sbjct: 347 LFSPSLATAASLLEVNPPDLMSCLTSRTLITRGETVSTPLSREQALDVRDAFVKGIYGRL 406
Query: 437 FNWMVTRINATL------ETKQPRQYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFF 490
F W+V +INA + + K R+ IG+LDI GFE F NSFEQLCINF NE LQQFF
Sbjct: 407 FVWIVDKINAAIYKPPSQDVKNSRRS-IGLLDIFGFENFAVNSFEQLCINFANEHLQQFF 465
Query: 491 NHHMFVLEQEEYKKEGIEWTFIDFGMDLQACIDLI-EKPMGIMSILEEECMFPKATDMTF 549
H+F LEQEEY E I+W I+F D Q +D+I KPM I+S+++EE FPK TD T
Sbjct: 466 VRHVFKLEQEEYDLESIDWLHIEF-TDNQDALDMIANKPMNIISLIDEESKFPKGTDTTM 524
Query: 550 KAKLYDNHLGKSN-NFQKPRNIKGKQEAHFSLIHYAGTVDYNILGWLEKNKDPLNETVVA 608
KL H K N N+ P+N E F + H+AG V Y G+LEKN+D L+ ++
Sbjct: 525 LHKLNSQH--KLNANYIPPKN---NHETQFGINHFAGIVYYETQGFLEKNRDTLHGDIIQ 579
Query: 609 LYQKSSLKLMATLFSSYATADTGDSGKSKGGKKKGSSFQTVSALHRENLNKLMTNLRTTH 668
L S K + +F + G + T+S+ + +L LM L
Sbjct: 580 LVHSSRNKFIKQIFQADVAM----------GAETRKRSPTLSSQFKRSLELLMRTLGACQ 629
Query: 669 PHFVRCIIPNERKAPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRILN 728
P FVRCI PNE K P + D L + QLR +G++E IRI R G+P R + +F +RYR+L
Sbjct: 630 PFFVRCIKPNEFKKPMLFDRHLCVRQLRYSGMMETIRIRRAGYPIRYSFVEFVERYRVLL 689
Query: 729 PVAIPEGQFIDSRKGTEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLSRIIT 788
P P + D R +++ ++ H+ ++ G TK+F K LLE RD+ ++ +
Sbjct: 690 PGVKPAYKQGDLRGTCQRMAEAVLGTHDDWQIGKTKIFLKDHHDMLLEVERDKAITDRVI 749
Query: 789 RMQAQARGQLMRIEFKKIVERRDALLVIQWNIRAFMGVKNWPWMKL-YFKIKPLLKSAET 847
+Q RG R F K+ ++A +IQ + R KN+ M+L + +++ L +S +
Sbjct: 750 LLQKVIRGFKDRSNFLKL---KNAATLIQRHWRGHNCRKNYGLMRLGFLRLQALHRSRKL 806
Query: 848 EKEMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLNDAEERC 907
++ ++ + + ++ RK ++ ++ L VQA + R
Sbjct: 807 HQQYRLARQRIIQFQARC-RAYLVRKAFRHRLWAV--------LTVQAYARGM--IARRL 855
Query: 908 DQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKK------RKLEDECSELKKDIDDLEL 961
Q ++ + + ++M RL +EE++ E++AKK RK ++ ++L ++ + EL
Sbjct: 856 HQRLRAEYLWRLEAEKM--RLAEEEKLRKEMSAKKAKEEAERKHQERLAQLAREDAEREL 913
Query: 962 TLAKVEKEKHATENKVKNLTEEM 984
KEK A K K L E+M
Sbjct: 914 ------KEKEAARRK-KELLEQM 929
Score = 33.9 bits (76), Expect = 1.6
Identities = 24/76 (31%), Positives = 38/76 (50%), Gaps = 8/76 (10%)
Query: 1527 ELEKVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEME 1586
E EK+RK++ +K A EEAE + ++ R E + E R+ E E+ME
Sbjct: 876 EEEKLRKEMSAKK-----AKEEAERKHQERLAQLAREDAERELKEKEAARRKKELLEQME 930
Query: 1587 QAKR---NHQRVVDSL 1599
+A+ NH +VD +
Sbjct: 931 RARHEPVNHSDMVDKM 946
>gi|189083798 myosin VIIA isoform 1 [Homo sapiens]
Length = 2215
Score = 471 bits (1213), Expect = e-132
Identities = 327/923 (35%), Positives = 487/923 (52%), Gaps = 71/923 (7%)
Query: 80 NPPKFDKIEDMAMLTFLHEPAVLFNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNAEVV 139
+P +EDM L L+E +L NL RY +IYTY+G V VNPY+ L +Y+ E +
Sbjct: 60 HPTSVHGVEDMIRLGDLNEAGILRNLLIRYRDHLIYTYTGSILVAVNPYQLLSIYSPEHI 119
Query: 140 AAYRGKKRSEAPPHIFSISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFASIA 199
Y KK E PPHIF+I+DN Y M + +Q +I+GESGAGKT +TK ++Q+ A+I+
Sbjct: 120 RQYTNKKIGEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFLAAIS 179
Query: 200 AIGDRGKKDNANANKGTLEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKL 259
+E Q+++A P LEAFGNAKT+RNDNSSRFGK+I IHF G +
Sbjct: 180 G------------QHSWIEQQVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKRGAI 227
Query: 260 ASADIETYLLEKSRVIFQLKAERNYHIFYQILSNKKPELLDMLLVTNNPYDYAFVSQGE- 318
A IE YLLEKSRV Q ERNYH+FY +L + L + DY +++ G
Sbjct: 228 EGAKIEQYLLEKSRVCRQALDERNYHVFYCMLEGMSEDQKKKLGL-GQASDYNYLAMGNC 286
Query: 319 VSVASIDDSEELMATDSAFDVLGFTSEEKAGVYKLTGAIMHYGNMKFKQKQRE--EQAEP 376
++ DS+E SA VL FT E + KL AI+H GN++++ + E + E
Sbjct: 287 ITCEGRVDSQEYANIRSAMKVLMFTDTENWEISKLLAAILHLGNLQYEARTFENLDACEV 346
Query: 377 DGTEDADKSAYLMGLNSADLLKGLCHPRVKVGNEYVTKGQSVQQVYYSIGALAKAVYEKM 436
+ +A L+ +N DL+ L + E V+ S +Q A K +Y ++
Sbjct: 347 LFSPSLATAASLLEVNPPDLMSCLTSRTLITRGETVSTPLSREQALDVRDAFVKGIYGRL 406
Query: 437 FNWMVTRINATL------ETKQPRQYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFF 490
F W+V +INA + + K R+ IG+LDI GFE F NSFEQLCINF NE LQQFF
Sbjct: 407 FVWIVDKINAAIYKPPSQDVKNSRRS-IGLLDIFGFENFAVNSFEQLCINFANEHLQQFF 465
Query: 491 NHHMFVLEQEEYKKEGIEWTFIDFGMDLQACIDLI-EKPMGIMSILEEECMFPKATDMTF 549
H+F LEQEEY E I+W I+F D Q +D+I KPM I+S+++EE FPK TD T
Sbjct: 466 VRHVFKLEQEEYDLESIDWLHIEF-TDNQDALDMIANKPMNIISLIDEESKFPKGTDTTM 524
Query: 550 KAKLYDNHLGKSN-NFQKPRNIKGKQEAHFSLIHYAGTVDYNILGWLEKNKDPLNETVVA 608
KL H K N N+ P+N E F + H+AG V Y G+LEKN+D L+ ++
Sbjct: 525 LHKLNSQH--KLNANYIPPKN---NHETQFGINHFAGIVYYETQGFLEKNRDTLHGDIIQ 579
Query: 609 LYQKSSLKLMATLFSSYATADTGDSGKSKGGKKKGSSFQTVSALHRENLNKLMTNLRTTH 668
L S K + +F + G + T+S+ + +L LM L
Sbjct: 580 LVHSSRNKFIKQIFQADVAM----------GAETRKRSPTLSSQFKRSLELLMRTLGACQ 629
Query: 669 PHFVRCIIPNERKAPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRILN 728
P FVRCI PNE K P + D L + QLR +G++E IRI R G+P R + +F +RYR+L
Sbjct: 630 PFFVRCIKPNEFKKPMLFDRHLCVRQLRYSGMMETIRIRRAGYPIRYSFVEFVERYRVLL 689
Query: 729 PVAIPEGQFIDSRKGTEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLSRIIT 788
P P + D R +++ ++ H+ ++ G TK+F K LLE RD+ ++ +
Sbjct: 690 PGVKPAYKQGDLRGTCQRMAEAVLGTHDDWQIGKTKIFLKDHHDMLLEVERDKAITDRVI 749
Query: 789 RMQAQARGQLMRIEFKKIVERRDALLVIQWNIRAFMGVKNWPWMKL-YFKIKPLLKSAET 847
+Q RG R F K+ ++A +IQ + R KN+ M+L + +++ L +S +
Sbjct: 750 LLQKVIRGFKDRSNFLKL---KNAATLIQRHWRGHNCRKNYGLMRLGFLRLQALHRSRKL 806
Query: 848 EKEMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLNDAEERC 907
++ ++ + + ++ RK ++ ++ L VQA + R
Sbjct: 807 HQQYRLARQRIIQFQARC-RAYLVRKAFRHRLWAV--------LTVQAYARGM--IARRL 855
Query: 908 DQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKK------RKLEDECSELKKDIDDLEL 961
Q ++ + + ++M RL +EE++ E++AKK RK ++ ++L ++ + EL
Sbjct: 856 HQRLRAEYLWRLEAEKM--RLAEEEKLRKEMSAKKAKEEAERKHQERLAQLAREDAEREL 913
Query: 962 TLAKVEKEKHATENKVKNLTEEM 984
KEK A K K L E+M
Sbjct: 914 ------KEKEAARRK-KELLEQM 929
Score = 33.9 bits (76), Expect = 1.6
Identities = 24/76 (31%), Positives = 38/76 (50%), Gaps = 8/76 (10%)
Query: 1527 ELEKVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEME 1586
E EK+RK++ +K A EEAE + ++ R E + E R+ E E+ME
Sbjct: 876 EEEKLRKEMSAKK-----AKEEAERKHQERLAQLAREDAERELKEKEAARRKKELLEQME 930
Query: 1587 QAKR---NHQRVVDSL 1599
+A+ NH +VD +
Sbjct: 931 RARHEPVNHSDMVDKM 946
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.128 0.340
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 63,281,911
Number of Sequences: 37866
Number of extensions: 2915669
Number of successful extensions: 62067
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 814
Number of HSP's successfully gapped in prelim test: 1580
Number of HSP's that attempted gapping in prelim test: 13298
Number of HSP's gapped (non-prelim): 15942
length of query: 1939
length of database: 18,247,518
effective HSP length: 117
effective length of query: 1822
effective length of database: 13,817,196
effective search space: 25174931112
effective search space used: 25174931112
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.