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Search of human proteins with 156104889
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|156104889 myeloid/lymphoid or mixed-lineage leukemia
(trithorax homolog, Drosophila); translocated to, 3 [Homo sapiens]
(568 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|156104889 myeloid/lymphoid or mixed-lineage leukemia (trithor... 1125 0.0
gi|21361272 myeloid/lymphoid or mixed-lineage leukemia (trithora... 540 e-153
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 100 3e-21
gi|169658378 trinucleotide repeat containing 18 [Homo sapiens] 87 5e-17
gi|42560244 peptidylprolyl isomerase G [Homo sapiens] 84 3e-16
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 82 1e-15
gi|125656165 THO complex 2 [Homo sapiens] 77 4e-14
gi|91206454 hypothetical protein LOC257415 isoform 2 [Homo sapiens] 75 1e-13
gi|91206456 hypothetical protein LOC257415 isoform 1 [Homo sapiens] 75 1e-13
gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1... 74 4e-13
gi|33356174 pinin, desmosome associated protein [Homo sapiens] 73 8e-13
gi|95147342 chromodomain helicase DNA binding protein 9 [Homo sa... 70 4e-12
gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens] 70 5e-12
gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens] 70 5e-12
gi|113415504 PREDICTED: similar to ribonucleic acid binding prot... 69 9e-12
gi|169166499 PREDICTED: similar to ribonucleic acid binding prot... 69 9e-12
gi|113415498 PREDICTED: similar to ribonucleic acid binding prot... 69 9e-12
gi|88973230 PREDICTED: similar to ribonucleic acid binding prote... 69 9e-12
gi|169166609 PREDICTED: similar to ribonucleic acid binding prot... 69 1e-11
gi|113415994 PREDICTED: similar to ribonucleic acid binding prot... 69 1e-11
gi|6857826 RNA-binding protein S1, serine-rich domain [Homo sapi... 69 1e-11
gi|18379334 RNA-binding protein S1, serine-rich domain [Homo sap... 69 1e-11
gi|68299795 chromodomain helicase DNA binding protein 1 [Homo sa... 67 3e-11
gi|27734775 hypothetical protein LOC286499 [Homo sapiens] 67 3e-11
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa... 67 4e-11
gi|217330641 IWS1 homolog [Homo sapiens] 67 4e-11
gi|154146223 splicing factor, arginine/serine-rich 130 [Homo sap... 67 4e-11
gi|154146193 splicing factor, arginine/serine-rich 130 [Homo sap... 67 4e-11
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 67 6e-11
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 67 6e-11
>gi|156104889 myeloid/lymphoid or mixed-lineage leukemia (trithorax
homolog, Drosophila); translocated to, 3 [Homo sapiens]
Length = 568
Score = 1125 bits (2910), Expect = 0.0
Identities = 568/568 (100%), Positives = 568/568 (100%)
Query: 1 MASSCAVQVKLELGHRAQVRKKPTVEGFTHDWMVFVRGPEHSNIQHFVEKVVFHLHESFP 60
MASSCAVQVKLELGHRAQVRKKPTVEGFTHDWMVFVRGPEHSNIQHFVEKVVFHLHESFP
Sbjct: 1 MASSCAVQVKLELGHRAQVRKKPTVEGFTHDWMVFVRGPEHSNIQHFVEKVVFHLHESFP 60
Query: 61 RPKRVCKDPPYKVEESGYAGFILPIEVYFKNKEEPRKVRFDYDLFLHLEGHPPVNHLRCE 120
RPKRVCKDPPYKVEESGYAGFILPIEVYFKNKEEPRKVRFDYDLFLHLEGHPPVNHLRCE
Sbjct: 61 RPKRVCKDPPYKVEESGYAGFILPIEVYFKNKEEPRKVRFDYDLFLHLEGHPPVNHLRCE 120
Query: 121 KLTFNNPTEDFRRKLLKAGGDPNRSIHTSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 180
KLTFNNPTEDFRRKLLKAGGDPNRSIHTSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS
Sbjct: 121 KLTFNNPTEDFRRKLLKAGGDPNRSIHTSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 180
Query: 181 SSSSSSSSSSTSFSKPHKLMKEHKEKPSKDSREHKSAFKEPSRDHNKSSKESSKKPKENK 240
SSSSSSSSSSTSFSKPHKLMKEHKEKPSKDSREHKSAFKEPSRDHNKSSKESSKKPKENK
Sbjct: 181 SSSSSSSSSSTSFSKPHKLMKEHKEKPSKDSREHKSAFKEPSRDHNKSSKESSKKPKENK 240
Query: 241 PLKEEKIVPKMAFKEPKPMSKEPKPDSNLLTITSGQDKKAPSKRPPISDSEELSAKKRKK 300
PLKEEKIVPKMAFKEPKPMSKEPKPDSNLLTITSGQDKKAPSKRPPISDSEELSAKKRKK
Sbjct: 241 PLKEEKIVPKMAFKEPKPMSKEPKPDSNLLTITSGQDKKAPSKRPPISDSEELSAKKRKK 300
Query: 301 SSSEALFKSFSSAPPLILTCSADKKQIKDKSHVKMGKVKIESETSEKKKSTLPPFDDIVD 360
SSSEALFKSFSSAPPLILTCSADKKQIKDKSHVKMGKVKIESETSEKKKSTLPPFDDIVD
Sbjct: 301 SSSEALFKSFSSAPPLILTCSADKKQIKDKSHVKMGKVKIESETSEKKKSTLPPFDDIVD 360
Query: 361 PNDSDVEENISSKSDSEQPSPASSSSSSSSSFTPSQTRQQGPLRSIMKDLHSDDNEEESD 420
PNDSDVEENISSKSDSEQPSPASSSSSSSSSFTPSQTRQQGPLRSIMKDLHSDDNEEESD
Sbjct: 361 PNDSDVEENISSKSDSEQPSPASSSSSSSSSFTPSQTRQQGPLRSIMKDLHSDDNEEESD 420
Query: 421 EVEDNDNDSEMERPVNRGGSRSRRVSLSDGSDSESSSASSPLHHEPPPPLLKTNNNQILE 480
EVEDNDNDSEMERPVNRGGSRSRRVSLSDGSDSESSSASSPLHHEPPPPLLKTNNNQILE
Sbjct: 421 EVEDNDNDSEMERPVNRGGSRSRRVSLSDGSDSESSSASSPLHHEPPPPLLKTNNNQILE 480
Query: 481 VKSPIKQSKSDKQIKNGECDKAYLDELVELHRRLMTLRERHILQQIVNLIEETGHFHITN 540
VKSPIKQSKSDKQIKNGECDKAYLDELVELHRRLMTLRERHILQQIVNLIEETGHFHITN
Sbjct: 481 VKSPIKQSKSDKQIKNGECDKAYLDELVELHRRLMTLRERHILQQIVNLIEETGHFHITN 540
Query: 541 TTFDFDLCSLDKTTVRKLQSYLETSGTS 568
TTFDFDLCSLDKTTVRKLQSYLETSGTS
Sbjct: 541 TTFDFDLCSLDKTTVRKLQSYLETSGTS 568
>gi|21361272 myeloid/lymphoid or mixed-lineage leukemia (trithorax
homolog, Drosophila); translocated to, 1 [Homo sapiens]
Length = 559
Score = 540 bits (1391), Expect = e-153
Identities = 315/580 (54%), Positives = 385/580 (66%), Gaps = 34/580 (5%)
Query: 1 MASSCAVQVKLELGHRAQVRKKPTVEGFTHDWMVFVRGPEHSNIQHFVEKVVFHLHESFP 60
M + C VQV+LELGHRAQ+RKKPT EGFTHDWMVFVRGPE +IQHFVEKVVF LH+SFP
Sbjct: 1 MDNQCTVQVRLELGHRAQLRKKPTTEGFTHDWMVFVRGPEQCDIQHFVEKVVFWLHDSFP 60
Query: 61 RPKRVCKDPPYKVEESGYAGFILPIEVYFKNKEEPRKVRFDYDLFLHLEGHPPVNHLRCE 120
+P+RVCK+PPYKVEESGYAGFI+PIEV+FKNKEEPRKV F YDLFL+LEG+PPVNHLRCE
Sbjct: 61 KPRRVCKEPPYKVEESGYAGFIMPIEVHFKNKEEPRKVCFTYDLFLNLEGNPPVNHLRCE 120
Query: 121 KLTFNNPTEDFRRKLLKAGGDPNRSIHTSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 180
KLTFNNPT +FR KLL+AGG + S S + S+ S + S
Sbjct: 121 KLTFNNPTTEFRYKLLRAGGVMVMPEGADTVSRPSPDYPMLPTIPLSAFSDPKKTKPSHG 180
Query: 181 SSSSSSSSSSTSFSKPHKLMKEHKEKPSKDSREHKSAFKEPSRDHNKSSKESSKKPKENK 240
S ++ SS T SKPHK+ KEH+E+P KDS E KS+ KE R+ KSSK++S+K E +
Sbjct: 181 SKDANKESSKT--SKPHKVTKEHRERPRKDS-ESKSSSKELEREQAKSSKDTSRKLGEGR 237
Query: 241 PLKEEKI-VPKMAFKEPKPMSKEPKPDSNLLTITSG-------QDKKAPSKRPPISDSEE 292
KEEK PK AFKEPK KE K +S T G +A SKRP +DS +
Sbjct: 238 LPKEEKAPPPKAAFKEPKMALKETKLES---TSPKGGPPPPPPPPPRASSKRPATADSPK 294
Query: 293 LSAKKRKKSSSEALFKSFSSAPPLILTCS-ADKKQIKDKSHVKMGKVKIESETSEKKKST 351
SAKK+KKSSS+ + ++P + S +DKK KDKS + KVK ESE E KK+
Sbjct: 295 PSAKKQKKSSSKGSRSAPGTSPRTSSSSSFSDKKPAKDKSSTRGEKVKAESEPREAKKA- 353
Query: 352 LPPFDDIVDPNDSDVEENISSKSDSEQPSPASSSSSSSSS----FTPSQTRQQGPLRSIM 407
++ +S+ E+ S KS+S Q SP++SSSSS SS F PSQ QGPLRS++
Sbjct: 354 -------LEVEESNSEDEASFKSESAQSSPSNSSSSSDSSSDSDFEPSQNHSQGPLRSMV 406
Query: 408 KDLHSDDNEEESDEVEDNDNDSEMERPVNRGGSRSRRVSLSDGSDSESSSASSPLHHEPP 467
+DL S EESDE +D+ + E N G R R+S SD S+ +S P PP
Sbjct: 407 EDLQS----EESDE-DDSSSGEEAAGKTNPG--RDSRLSFSDSESDNSADSSLPSREPPP 459
Query: 468 PPLLKTNNNQILEVKSPIKQSKSDKQIKNGECDKAYLDELVELHRRLMTLRERHILQQIV 527
P N+++ +SP SK +K +K G DKAY DELVELHRRLM LRER++LQQIV
Sbjct: 460 PQKPPPPNSKVSGRRSPESCSKPEKILKKGTYDKAYTDELVELHRRLMALRERNVLQQIV 519
Query: 528 NLIEETGHFHITNTTFDFDLCSLDKTTVRKLQSYLETSGT 567
NLIEETGHF++TNTTFDFDL SLD+TTVRKLQS LE T
Sbjct: 520 NLIEETGHFNVTNTTFDFDLFSLDETTVRKLQSCLEAVAT 559
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 100 bits (250), Expect = 3e-21
Identities = 94/320 (29%), Positives = 126/320 (39%), Gaps = 24/320 (7%)
Query: 141 DPNRSIHTSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFSKPHKLM 200
D + S +S+SS SS SS SS+SS SS+SS SS+SS SS S+SS SS SS S
Sbjct: 931 DNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSD 990
Query: 201 KEHKEKPSKDSREHKSAFKEPSRDHNKSSKESSKKPKENKPLKEEKIVPKMAFKEPKPMS 260
S S S+ S D + SS S+ N + + S
Sbjct: 991 SSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDS--SDSSDSSDSSDS 1048
Query: 261 KEPKPDSNLLTITSGQDKKAPSKRPPISDSEELSAKKRKKSSSEALFKSFSSAPPLILTC 320
+ SN + D S SDS + S SS + S SS
Sbjct: 1049 SDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSD------- 1101
Query: 321 SADKKQIKDKSHVKMGKVKIESETSEKKKSTLPPFDDIVDPNDSDVEENISSKSDSEQPS 380
S+D D S S++S+ S+ D D +DS N S SDS + S
Sbjct: 1102 SSDSSDSSDSSD--------SSDSSDSSNSS--DSSDSSDSSDSSDSSNSSDSSDSSESS 1151
Query: 381 PASSSSSSSSSFTPSQTRQQGPLRSIMKDLHSDDNEEESDEVEDNDNDSEMERPVNRGGS 440
+S SS SS S S + S D+ + SD + +D+ + + S
Sbjct: 1152 DSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1211
Query: 441 RSRRVSLSDGSDSESSSASS 460
S SD SDS SS SS
Sbjct: 1212 DS-----SDSSDSSDSSDSS 1226
Score = 100 bits (248), Expect = 5e-21
Identities = 95/337 (28%), Positives = 129/337 (38%), Gaps = 17/337 (5%)
Query: 141 DPNRSIHTSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFSKPHKLM 200
D + S +S S+SS SS SS+SS SS SS SS SS SS SS+SS SS SS S +
Sbjct: 961 DSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSD 1020
Query: 201 KEHKEKPSKDSREHKSAFKEPSRDHNKSSKES-SKKPKENKPLKEEKIVPKMAFKEPKPM 259
+ S S S+ S D + SS S S ++ + +
Sbjct: 1021 SSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSD 1080
Query: 260 SKEPKPDSNLLTITSGQDKKAPSKRPPISDSEELSAKKRKKSSSEALFKSFSSAPPLILT 319
S E S+ + D S SDS + S +SS++ S SS
Sbjct: 1081 SSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSD------ 1134
Query: 320 CSADKKQIKDKSHVKMGKVKIESETSEKKKSTLPPFDDIVDPNDSDVEENISSKSDSEQP 379
S+D D S +S S + D D +DS N S SDS
Sbjct: 1135 -SSDSSNSSDSSDSSESSDSSDSSDSSDSSDS----SDSSDSSDSSDSSNSSDSSDSSDS 1189
Query: 380 SPASSSSSSSSSFTPSQTRQQGPLRSIMKDLHSDDNEEESDEVEDNDNDSEMERPVNRGG 439
S +S SS SS S S + S D+ + SD E +D+ + +
Sbjct: 1190 SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNS 1249
Query: 440 SRSRRVSLSDGSDSESSSASSPLHHEPPPPLLKTNNN 476
S S SD SDS S++ S + NNN
Sbjct: 1250 SDS-----SDSSDSSDSTSDSNDESDSQSKSGNGNNN 1281
Score = 99.4 bits (246), Expect = 8e-21
Identities = 89/314 (28%), Positives = 124/314 (39%), Gaps = 8/314 (2%)
Query: 149 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFSKPHKLMKEHKEKPS 208
SS SS SS SS S S SS+ S SS+SS SS SS SS+SS S+ S ++ S
Sbjct: 838 SSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDS 897
Query: 209 KDSREHKSAFKEPSRDHNKSSKESSKKPKENKPLKEEKIVPKMAFKEPKPMSKEPKPDSN 268
+S + S+ S D + SS S N + DS+
Sbjct: 898 SNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSS 957
Query: 269 LLTITSGQDKKAPSKRPPISDSEELSAKKRKKSSSEALFKSFSSAPPLILTCSADKKQIK 328
+ +S + S SDS S SS++ S SS + S+D
Sbjct: 958 NSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNS----SDSSDSSDSS 1013
Query: 329 DKSHVKMGKVKIESETSEKKKSTLPPFD--DIVDPNDSDVEENISSKSDSEQPSPASSSS 386
D S+ +S S + D D D +DS N S SDS S +S SS
Sbjct: 1014 DSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSS 1073
Query: 387 SSSSSFTPSQTRQQGPLRSIMKDLHSDDNEEESDEVEDNDNDSEMERPVNRGGSRSRRVS 446
SS S S++ + S D+ + SD + +D+ + + S S
Sbjct: 1074 DSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSS--D 1131
Query: 447 LSDGSDSESSSASS 460
SD SDS +SS SS
Sbjct: 1132 SSDSSDSSNSSDSS 1145
Score = 99.0 bits (245), Expect = 1e-20
Identities = 93/320 (29%), Positives = 133/320 (41%), Gaps = 18/320 (5%)
Query: 141 DPNRSIHTSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFSKPHKLM 200
D + S ++S SS SS SS SS+SS SS+SS SS+SS SS SS SS SS S+ S
Sbjct: 996 DSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSS 1055
Query: 201 KEHKEKPSKDSREHKSAFKEPSRDHNKSSKESSKKPKENKP-LKEEKIVPKMAFKEPKPM 259
S DS + S+ S D + SS+ S N + +
Sbjct: 1056 NSSDSSDSSDSSD--SSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSD 1113
Query: 260 SKEPKPDSNLLTITSGQDKKAPSKRPPISDSEELSAKKRKKSSSEALFKSFSSAPPLILT 319
S + SN + D S SDS + S SS++ S SS
Sbjct: 1114 SSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSD------ 1167
Query: 320 CSADKKQIKDKSHVKMGKVKIESETSEKKKSTLPPFDDIVDPNDSDVEENISSKSDSEQP 379
S+D D S+ S++S+ S+ D D +DS + S SDS
Sbjct: 1168 -SSDSSDSSDSSN--SSDSSDSSDSSDSSDSS-----DSSDSSDSSDSSDSSDSSDSSDS 1219
Query: 380 SPASSSSSSSSSFTPSQTRQQGPLRSIMKDLHSDDNEEESDEVEDNDNDSEMERPVNRGG 439
S +S SS SS S S + S D+ + SD D++++S+ + G
Sbjct: 1220 SDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGN 1279
Query: 440 SR-SRRVSLSDGSDSESSSA 458
+ S S S+GSDS S++
Sbjct: 1280 NNGSDSDSDSEGSDSNHSTS 1299
Score = 98.6 bits (244), Expect = 1e-20
Identities = 91/323 (28%), Positives = 131/323 (40%), Gaps = 5/323 (1%)
Query: 143 NRSIHTSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFSKPHKLMKE 202
N S + SS SS+SS SS SS SS S SS SS SS+S+SS S SS+SS S +
Sbjct: 685 NSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSS 744
Query: 203 HKEKPSKDSREHKSAFKEPSRDHNKSSKESSKKPKENKPLKEEKIVPKMAFKEPKPMSKE 262
S S S+ S D + SS S N + +
Sbjct: 745 DSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSS 804
Query: 263 PKPDSNLLTITSGQDKKAPSKRPPISDSEELSAKKRKKSSSEALFKSFS-SAPPLILTCS 321
DS+ + +S D S SDS + S SS++ S S S+ + S
Sbjct: 805 NSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNS 864
Query: 322 ADKKQIKDKSHVKMGKVKIESE----TSEKKKSTLPPFDDIVDPNDSDVEENISSKSDSE 377
+D D S+ +S +S+ S+ D D ++S + S+ SDS
Sbjct: 865 SDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSS 924
Query: 378 QPSPASSSSSSSSSFTPSQTRQQGPLRSIMKDLHSDDNEEESDEVEDNDNDSEMERPVNR 437
+ S +S +S+SS S S + + +S D+ SD + N +DS +
Sbjct: 925 ESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSD 984
Query: 438 GGSRSRRVSLSDGSDSESSSASS 460
S SD SDS +SS SS
Sbjct: 985 SSDSSDSSDSSDSSDSSNSSDSS 1007
Score = 97.4 bits (241), Expect = 3e-20
Identities = 91/328 (27%), Positives = 132/328 (40%), Gaps = 10/328 (3%)
Query: 141 DPNRSIHTSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS----SSSSSSTSFSKP 196
D N S + +S SS SS+SS+SS SS SS SS SSSSS SS+SS SS SS++S S
Sbjct: 644 DSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSD 703
Query: 197 HKLMKEHKEKPSKDSREHKSAFKEPSRDHNKSSKESSKKPKENKPLKEEKIVPKMAFKEP 256
+ S DS S+ + S + S +S ++ +
Sbjct: 704 SSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSN 763
Query: 257 KPMSKEPKPDSNLLTITSGQDKKAPSKRPPISDSEELSAKKRKKSSSEALFKSFS----S 312
S + S+ ++ D S SDS S SS++ S S S
Sbjct: 764 SSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNS 823
Query: 313 APPLILTCSADKKQIKDKSHVKMGKVKIESETSEKKKSTLPPFDDIVDPNDSDVEENISS 372
+ + S+D D S +S++S + S+ D D +DS + S
Sbjct: 824 SDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSS--NSSDSSDSSDSSNSSDSSD 881
Query: 373 KSDSEQPSPASSSSSSSSSFTPSQTRQQGPLRSIMKDLHSDDNEEESDEVEDNDNDSEME 432
SDS + S +S SS SS+S + S SD +E + N +DS
Sbjct: 882 SSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNS 941
Query: 433 RPVNRGGSRSRRVSLSDGSDSESSSASS 460
+ S S+ SDS +SS SS
Sbjct: 942 SDSSDSSDSSNSSDSSNSSDSSNSSDSS 969
Score = 97.4 bits (241), Expect = 3e-20
Identities = 90/328 (27%), Positives = 135/328 (41%), Gaps = 13/328 (3%)
Query: 141 DPNRSIHTSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFSKPHKLM 200
D + S +S SS SS SS SS SS+SS SS SS SS SS+SS SS+SS S++ S
Sbjct: 978 DSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSS 1037
Query: 201 KEHKEKPSKDSREHK-SAFKEPSRDHNKSSKES-SKKPKENKPLKEEKIVPKMAFKEPKP 258
S DS + S+ S D + SS S S ++ E +
Sbjct: 1038 DSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSS 1097
Query: 259 MSKEPKPDSNLLTITSGQDKKAPSKRPPISDSEELSAKKRKKSSSEALFKSFSSAPPLIL 318
S + S+ + D S SDS + S +SS++ S SS
Sbjct: 1098 DSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDS---- 1153
Query: 319 TCSADKKQIKDKSHVKMGKVKIESETSEKKKSTLPPFD--DIVDPNDSDVEENISSKSDS 376
+ S+D D S +S S + D D D +DS + S SDS
Sbjct: 1154 SDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDS 1213
Query: 377 EQPSPASSSSSSSSSFTPSQTRQQGPLRSIMKDLHSDDNEEESDEVEDNDNDSEMERPVN 436
S +S SS SS S +++ +S D+ + SD + + ++ +
Sbjct: 1214 SDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQS 1273
Query: 437 RGGSRSRRVSLSDGSDSESSSASSPLHH 464
+ G+ + ++GSDS+S S S +H
Sbjct: 1274 KSGNGN-----NNGSDSDSDSEGSDSNH 1296
Score = 96.3 bits (238), Expect = 7e-20
Identities = 90/313 (28%), Positives = 123/313 (39%), Gaps = 10/313 (3%)
Query: 149 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFSKPHKLMKEHKEKPS 208
S+SSS S SS S SS SS S SS SS+SS SS SS SS SS +S S K E S
Sbjct: 574 SNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDS 633
Query: 209 KDSREHKSAFKEPSRDHNKSSKESSKKPKENKPLKEEKIVPKMAFKEPKPMSKEPKPDSN 268
DS + S D + +S S N + + + DS+
Sbjct: 634 SDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSS 693
Query: 269 LLTITSGQDKKAPSKRPPISDSEELSAKKRKKSSSEALFKSFSSAPPLILTCSADKKQIK 328
+ +S + S SDS + S S S S S+ + S+D
Sbjct: 694 DSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSS 753
Query: 329 DKSHVKMGKVKIESETSEKKKSTLPPFDDIVDPNDSDVEENISSKSDSEQPSPASSSS-S 387
D S +S S + D + +DS+ N S SDS S +S+SS S
Sbjct: 754 DSSDSSDSSNSSDSSDSSDSSDS----SDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDS 809
Query: 388 SSSSFTPSQTRQQGPLRSIMKDLHSDDNEEESDEVEDNDNDSEMERPVNRGGSRSRRVSL 447
S SS + S D N +S + D+ + S+ + +RS +
Sbjct: 810 SDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSD-----SSNRSDSSNS 864
Query: 448 SDGSDSESSSASS 460
SD SDS SS SS
Sbjct: 865 SDSSDSSDSSNSS 877
Score = 88.2 bits (217), Expect = 2e-17
Identities = 78/292 (26%), Positives = 118/292 (40%), Gaps = 4/292 (1%)
Query: 141 DPNRSIHTSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFSKPHKLM 200
D + S ++S SS+SS SS+SS SS SS SS SS SS SS SS SS+SS S+ S
Sbjct: 1011 DSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSS 1070
Query: 201 KEHKEKPSKDSREHKSAFKEPSRDHNKSSKESSKKPKENKPLKEEKIVPKMAFKEPKPMS 260
S DS E + + S + S S ++ + + S
Sbjct: 1071 DSSDSSDSSDSSESSDS-SDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDS 1129
Query: 261 KEPKPDSNLLTITSGQDKKAPSKRPPISDSEELSAKKRKKSSSEALFKSFSSAPPLILTC 320
+ S+ + D S SDS + S SS++ S +S+ +
Sbjct: 1130 SDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSS-NSSDSSDSSD 1188
Query: 321 SADKKQIKDKSHVKMGKVKIESETSEKKKSTLPPFD--DIVDPNDSDVEENISSKSDSEQ 378
S+D D S +S S + D D D N+S + S SDS
Sbjct: 1189 SSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSN 1248
Query: 379 PSPASSSSSSSSSFTPSQTRQQGPLRSIMKDLHSDDNEEESDEVEDNDNDSE 430
S +S SS SS S + S +S + + D++ +S+ + N + S+
Sbjct: 1249 SSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGSDSNHSTSD 1300
Score = 85.9 bits (211), Expect = 9e-17
Identities = 87/317 (27%), Positives = 123/317 (38%), Gaps = 6/317 (1%)
Query: 145 SIHTSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFSKPHKLMKEHK 204
S +S SS SS SS SS S S SS S S SS S S S SS S+SS +S +
Sbjct: 604 SSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSS-DNSDSSDSSNS 662
Query: 205 EKPSKDSREHKSAFKEPSRDHNKSSKESSKKPKENKPLKEEKIVPKMAFKEPKPMSKEPK 264
S S S+ S D + SS S N E + + S
Sbjct: 663 SNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNS--SESSDSSDSSDSDSSDSSDSSN 720
Query: 265 PDSNLLTITSGQDKKAPSKRPPISDSEELSAKKRKKSSSEALFKSFSSAPPLILTCSADK 324
+S+ ++ D S SDS + S SS++ S S+ + S+D
Sbjct: 721 SNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDS-SNSSDSSDSSDSSDSSDS 779
Query: 325 KQIKDKSHVKMGKVKIESETSEKKKSTLPPFDDIVDPNDSDVEENISSKSDSEQPSPASS 384
D + +S S S D D +DSD + S + S+ ++S
Sbjct: 780 SNSSDSNDSSNSSDSSDSSNS-SDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNS 838
Query: 385 SSSSSSSFTPSQTRQQGPLRS-IMKDLHSDDNEEESDEVEDNDNDSEMERPVNRGGSRSR 443
S SS SS + + RS S D+ + S+ + +D+ E + S S
Sbjct: 839 SDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSS 898
Query: 444 RVSLSDGSDSESSSASS 460
S SD SDS +SS SS
Sbjct: 899 NSSDSDSSDSSNSSDSS 915
Score = 79.0 bits (193), Expect = 1e-14
Identities = 83/333 (24%), Positives = 126/333 (37%), Gaps = 35/333 (10%)
Query: 130 DFRRKLLKAGGDPNRSIHTSSSSSSSSSSSSSSSSSSSSS--SSSSSSSSSSSSSSSSSS 187
DF K ++ G DPN S ++ + ++S S ++SSS +S S S + + S S +
Sbjct: 454 DFDDKSMQ-GDDPNSSDESNGNDDANSESDNNSSSRGDASYNSDESKDNGNGSDSKGAED 512
Query: 188 SSSTSFSKPHKLMKEHKEKPSKDSREHKSAFKEPSRDHNKSSKESSKKPKENKPLKEEKI 247
S S S + D + + K S + S +SS
Sbjct: 513 DDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNS------------ 560
Query: 248 VPKMAFKEPKPMSKEPKPDSNLLTITSGQDKKAPSKRPPISDSEELSAKKRKKSSSEALF 307
+ S DSN + + D + SDS + S SS++
Sbjct: 561 ------SDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSD--SDSSDSSNSSDSSDSSDSSD 612
Query: 308 KSFSSAPPLILTCSADKKQIKDKSHVKMGKVKIESETSEKKKSTLPPFDDIVDPNDSDVE 367
S SS S+D K KS +S++S+ S D D +DS
Sbjct: 613 SSDSSD-------SSDSKSDSSKSESDSSDSDSKSDSSDSNSSDS---SDNSDSSDSSNS 662
Query: 368 ENISSKSDSEQPSPASSSSSSSSSFTPSQTRQQGPLRSIMKDLHSDDNEEESDEVEDNDN 427
N S SDS S +SSSS SS+S S + S SD ++ +S + D+ N
Sbjct: 663 SNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSS--NSSESSDSSDSSDSDSSDSSDSSN 720
Query: 428 DSEMERPVNRGGSRSRRVSLSDGSDSESSSASS 460
+ + + S + SD SDS SS SS
Sbjct: 721 SNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSS 753
Score = 43.9 bits (102), Expect = 4e-04
Identities = 68/332 (20%), Positives = 121/332 (36%), Gaps = 37/332 (11%)
Query: 153 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFSKPHKLMKEHKEK--PSKD 210
+S S S + + S + + SS++S + H +H + D
Sbjct: 241 NSDGSPSGNGADEDEDEGSGDDEDEEAGNGKDSSNNSKGQEGQDHGKEDDHDSSIGQNSD 300
Query: 211 SREH------KSAFKEPSRDHNKSSKESSKKPKENKPLKEEKIVPKMAFKEPKPMSKEPK 264
S+E+ + E D S+E+S E+ + + K+ +E K +
Sbjct: 301 SKEYYDPEGKEDPHNEVDGDKTSKSEENSAGIPEDNGSQRIEDTQKLNHRESKRVENRIT 360
Query: 265 PDSNLLTITSGQDKKAPSKRPPISDSEELSAKKRKKSSSEALFKSFSSAPPLILTCSADK 324
+S + QDK K P S + ++ + K + K +IL K
Sbjct: 361 KESETHAVGKSQDKGIEIKGPS-SGNRNITKEVGKGNEG----KEDKGQHGMIL----GK 411
Query: 325 KQIKDKSHVKMGKVKIE-----SETSEKKKSTLPPFDDIVDPNDSDVEENISSKSDSEQP 379
+K + V V IE SE K + D D DS ++ S + D
Sbjct: 412 GNVKTQGEV----VNIEGPGQKSEPGNKVGHSNTGSDSNSDGYDSYDFDDKSMQGDDPNS 467
Query: 380 SPASSSSSSSSSFTPSQTRQQGPLRSIMKDLHSDDNEEESDEVEDNDNDSEME---RPVN 436
S S+ + ++S + + + +G + + N +S ED+D+DS + N
Sbjct: 468 SDESNGNDDANSESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSN 527
Query: 437 RGGSRSR--------RVSLSDGSDSESSSASS 460
G+ SD SDS+SS +S+
Sbjct: 528 GNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSN 559
>gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]
Length = 2968
Score = 86.7 bits (213), Expect = 5e-17
Identities = 65/159 (40%), Positives = 87/159 (54%), Gaps = 3/159 (1%)
Query: 145 SIHTSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFSKPHKLMKEHK 204
S +SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS+S S
Sbjct: 2614 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTT 2673
Query: 205 EKPSKDSREHKSAFKEPSRDHNKSSKESSKKPKENKPLKEEKIVPKMAFKEPKPMSKEPK 264
++ S S + ++A P+ + + +K K+ + P P+P + P+
Sbjct: 2674 DEDSSCSSDDEAA-PAPTAGPSAQAALPTKATKQAGKARPSAHSPGKKTPAPQPQAPPPQ 2732
Query: 265 PDSNLLTITSGQDKKAPSKRPPI--SDSEELSAKKRKKS 301
P L K P KR + ++EL+ ++R S
Sbjct: 2733 PTQPLQPKAQAGAKSRPKKREGVHLPTTKELAKRQRLPS 2771
Score = 45.8 bits (107), Expect = 1e-04
Identities = 70/300 (23%), Positives = 110/300 (36%), Gaps = 45/300 (15%)
Query: 200 MKEHKEKPSKDSREHKSAFKEPSR-----------DHNKSSKESSKKPKENKPLKEE--- 245
M + KP K +S K P R DH + SKK KE L+E+
Sbjct: 2430 MPATRPKPKKARAAEESGAKGPRRPGEEAELLVKLDHEGVTSPKSKKAKEALLLREDPGA 2489
Query: 246 ------KIVPKMAFKEPKPMSKEPKP------DSNL-------LTITSGQDKKAPSKRPP 286
K + + P S EPK D +L LT + K+P K
Sbjct: 2490 GGWQEPKSLLSLGSYPPAAGSSEPKAPWPKATDGDLAQEPGPGLTFEDSGNPKSPDK--- 2546
Query: 287 ISDSEELSAKKRKKSSSEALFKSFSSAPPLILTCSADKKQIKDKSHVKMGKVKIESETSE 346
+ +E+ A++ + SSS + S SS+ + ++ DK+ + ++
Sbjct: 2547 -AQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAA 2605
Query: 347 KKKSTLPPFDDIVDPNDSDVEENISSKSDSEQPSPASSSSSSSSSFTPSQTRQQGPLRSI 406
++ P + S + SS S S S +SSSSSSSSS + S + S
Sbjct: 2606 SSRAASPA-------SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2658
Query: 407 MKDLHSDDNEEESDEVEDNDNDSEMERPVNRGGSRSRRVSLSDGSDSESSSASSPLHHEP 466
S + S ED+ S+ E S + +L + ++ A P H P
Sbjct: 2659 SSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALPTKATKQAGKA-RPSAHSP 2717
Score = 42.4 bits (98), Expect = 0.001
Identities = 45/214 (21%), Positives = 76/214 (35%), Gaps = 15/214 (7%)
Query: 141 DPNRSIHTSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFSKPHKLM 200
+P + S + S + + + S SSSSSSS SSSSSSSSSSS S ++ +
Sbjct: 2528 EPGPGLTFEDSGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEG 2587
Query: 201 KEHKEKPSKDSREHKSAFKEPSRDHNKSSKESSKKPKENKPLKEEKIVPKMAFKEPKPMS 260
++ + + SA + SS SS + S
Sbjct: 2588 DKNGDGGCGTGGRNCSAASSRAASPASSSSSSSSSSSSS---------------SSSSSS 2632
Query: 261 KEPKPDSNLLTITSGQDKKAPSKRPPISDSEELSAKKRKKSSSEALFKSFSSAPPLILTC 320
S+ + +S + S S S S+ + ++ S A P
Sbjct: 2633 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAG 2692
Query: 321 SADKKQIKDKSHVKMGKVKIESETSEKKKSTLPP 354
+ + + K+ + GK + + + KK P
Sbjct: 2693 PSAQAALPTKATKQAGKARPSAHSPGKKTPAPQP 2726
Score = 32.0 bits (71), Expect = 1.6
Identities = 92/436 (21%), Positives = 159/436 (36%), Gaps = 77/436 (17%)
Query: 129 EDFRRKLLKAG-GDPNRSIHTSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 187
E+ R L + G G P + H S+ S S SS SS S +S +
Sbjct: 1515 EEPHRSLARRGPGRPRKRTHAPSALSPPRKRGKSGHSSGKLSSKSLLTSDDYELGAGIRK 1574
Query: 188 SSSTSFSKPHKLMKEHKEKPSKDSREHKSAFKEPSRDHNKSSKESSKKPKENKPLKEEKI 247
S + L+ K + + + A S D K KK ++ K+
Sbjct: 1575 RHKGSEEEHDALIGMGKARGRNQTWDEHEA----SSDFISQLKIKKKKMASDQEQLASKL 1630
Query: 248 VPKMAF-KEPKPMSKEPKPDSNLLTITSGQDKKAPSKRPPISDSEELSAKKRKKSSSEAL 306
++ K+ K S DS G+ K + ++ + L K RK + ++ L
Sbjct: 1631 DKALSLTKQDKLKSPFKFSDS-----AGGKSKTSGGCGRYLTPYDSLLGKNRK-ALAKGL 1684
Query: 307 FKSFSSAPPLILTCSADKKQIKDKSHVKMGKVKIESETSEKKKSTLPPFDDIVDPN--DS 364
S S+ ++ K K K K+++ + + KS PF V ++
Sbjct: 1685 GLSLKSS-----------REGKHKRAAKTRKMEVGFKARGQPKSAHSPFASEVSSYSYNT 1733
Query: 365 DVEENISSKSDSEQPSPASSSSSSSSSFT------------------------------P 394
D EE+ D E P+ SSS + S P
Sbjct: 1734 DSEEDEEFLKD-EWPAQGPSSSKLTPSLLCSMVAKNSKAAGGPKLTKRGLAAPRTLKPKP 1792
Query: 395 SQTRQQGPLRSIMKDLH-----SDDNEE-----ESDEVEDNDNDSEMERPVNRGGSR--S 442
+ +R+Q P ++++ SD +EE ES E ED + + E E + GG R +
Sbjct: 1793 ATSRKQ-PFCLLLREAEARSSFSDSSEESFDQDESSEEEDEEEELEEEDEASGGGYRLGA 1851
Query: 443 RRVSLSDGSDSE-----SSSASSPLHHEPPPPLLKTNNNQILEVKSPIKQSKSDKQIKNG 497
R +LS G + + A+S L P P + + + LE K ++ + + +
Sbjct: 1852 RERALSPGLEESGLGLLARFAASAL---PSPTVGPSLSVVQLEAKQKARKKEERQSLLGT 1908
Query: 498 ECDKAYLDELVELHRR 513
E + + V++ +R
Sbjct: 1909 EFEYTDSESEVKVRKR 1924
>gi|42560244 peptidylprolyl isomerase G [Homo sapiens]
Length = 754
Score = 84.3 bits (207), Expect = 3e-16
Identities = 92/384 (23%), Positives = 155/384 (40%), Gaps = 37/384 (9%)
Query: 142 PNRSIHTSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFSKPH-KLM 200
P + SSSSSSSSSS S SSS S SSS SS S S++ S K H K
Sbjct: 179 PKSKVKKEEKKRHKSSSSSSSSSSDSDSSSDSQSSSDSSDSESATEEKSKKRKKKHRKNS 238
Query: 201 KEHKEKPSKDSREHKSAFKEPSRDHNKSSKESSKKPKENKPLKEEKIV-----PKMAFKE 255
++HK++ K + KSA E ++ ++ +S+ +P+E P+ E + + PK KE
Sbjct: 239 RKHKKEKKKRKKSKKSASSESEAENLEAQPQSTVRPEEIPPIPENRFLMRKSPPKADEKE 298
Query: 256 PKPMSKEPKPDSN------------LLTITSGQDKKAPSKRPPISDSEELSAKKRKKSSS 303
K +E + + N LL SG+ K R + S S + ++S +
Sbjct: 299 RKNRERERERECNPPNSQPASYQRRLLVTRSGRKIKGRGPRRYRTPSRSRSRDRFRRSET 358
Query: 304 EALFKSFSSAPPLILTCSADKKQIKDKSHVKMGKVKIESETSEKKKSTLPPFDDIVDPND 363
++ + S ++ DKS + K S K++ D + ++
Sbjct: 359 PPHWRQEMQRAQRMRVSSGERWIKGDKSELNEIKENQRSPVRVKERK----ITDHRNVSE 414
Query: 364 SDVEENISSKSDSEQPSPASSSSSSSSSFTPSQTRQQGPLRSIMKDLHSDDNEEESDEVE 423
S +N K + S + +S + + + R+ K + +S E +
Sbjct: 415 SPNRKNEKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSRSKSKEKSKSKERD 474
Query: 424 DNDNDSEMERPVNRGGSR-------SRRVSLSDGSDSESSSASSPLHHEPPPPLLKTNNN 476
N +E +R +R R + S S G D E S + L++ +N
Sbjct: 475 SKHNRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQERSRSKEKSKQ------LESKSN 528
Query: 477 QILEVKSPIKQSKSDKQIKNGECD 500
+ KS K ++ Q ++ ECD
Sbjct: 529 EHDHSKSKEKDRRA--QSRSRECD 550
Score = 38.9 bits (89), Expect = 0.013
Identities = 70/345 (20%), Positives = 121/345 (35%), Gaps = 46/345 (13%)
Query: 157 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFSKPHKLMKEHKEKPSKDSREHKS 216
S S + + S+S +S +K K K SK+ KS
Sbjct: 413 SESPNRKNEKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSRSKSKE----KS 468
Query: 217 AFKEPSRDHNKSSKE---SSKKPKENKPLKEEKIVPKMAFKEPKPMSKEPKPDSNLLTIT 273
KE HN++ ++ S K ++++ +KE KE + DS
Sbjct: 469 KSKERDSKHNRNEEKRMRSRSKGRDHENVKE----------------KEKQSDS------ 506
Query: 274 SGQDKKAPSKRPPISDSEELSAKKRKKSSSEALFKSFSSAPPLILTCSADKKQIKDKSHV 333
G+D++ + S++L +K + S++ K A C K
Sbjct: 507 KGKDQERSRSK---EKSKQLESKSNEHDHSKSKEKD-RRAQSRSRECDITK--------- 553
Query: 334 KMGKVKIESETSEKKKSTLPPFDDIVDPNDSDVEENISSKSDSEQPSPASSSSSSSSSFT 393
GK S T E+ +S +D D + EQ S S T
Sbjct: 554 --GKHSYNSRTRERSRSRDRSRRVRSRTHDRDRSRSKEYHRYREQEYRRRGRSRSRERRT 611
Query: 394 PSQTRQQGPLRSIMKDLHSDDNEEESDEVEDNDNDSEMERPVNRGGSRS--RRVSLSDGS 451
P + R +D S + EE +D + E + + S S R S S
Sbjct: 612 PPGRSRSKDRRRRRRDSRSSEREESQSRNKDKYRNQESKSSHRKENSESEKRMYSKSRDH 671
Query: 452 DSESSSASSPLHHEPPPPLLKTNNNQILEVKSPIKQSKSDKQIKN 496
+S ++S + P ++Q E+KS + ++K D++I++
Sbjct: 672 NSSNNSREKKADRDQSPFSKIKQSSQDNELKSSMLKNKEDEKIRS 716
Score = 34.3 bits (77), Expect = 0.31
Identities = 30/124 (24%), Positives = 46/124 (37%), Gaps = 3/124 (2%)
Query: 158 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFSKPHKLMKEHKEKPSKDSREHKSA 217
S S + S S S SS S S +K +E K K++ E +
Sbjct: 604 SRSRERRTPPGRSRSKDRRRRRRDSRSSEREESQSRNKDKYRNQESKSSHRKENSESEKR 663
Query: 218 FKEPSRDHNKSSKESSKK-PKENKPLKEEKIVPKMAFKEPKPMSKEPKPDSNLLTITSGQ 276
SRDHN S+ KK ++ P KI E K + K D + + +
Sbjct: 664 MYSKSRDHNSSNNSREKKADRDQSPF--SKIKQSSQDNELKSSMLKNKEDEKIRSSVEKE 721
Query: 277 DKKA 280
++K+
Sbjct: 722 NQKS 725
Score = 33.9 bits (76), Expect = 0.41
Identities = 24/90 (26%), Positives = 38/90 (42%), Gaps = 2/90 (2%)
Query: 154 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFSKPHKLMKEHKEKPSKDSRE 213
S SS S S + + S SS +S S S S+ H +EK + +
Sbjct: 628 SRSSEREESQSRNKDKYRNQESKSSHRKENSESEKRMYSKSRDHNSSNNSREKKADRDQS 687
Query: 214 HKSAFKEPSRDHNKSSKESSKKPKENKPLK 243
S K+ S+D+ K S K KE++ ++
Sbjct: 688 PFSKIKQSSQDN--ELKSSMLKNKEDEKIR 715
Score = 32.0 bits (71), Expect = 1.6
Identities = 28/114 (24%), Positives = 43/114 (37%), Gaps = 1/114 (0%)
Query: 150 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFSKPHKLMKEHKEKPSK 209
S S S SS S S + + S SS S S+ K S
Sbjct: 616 SRSKDRRRRRRDSRSSEREESQSRNKDKYRNQESKSSHRKENSESEKRMYSKSRDHNSSN 675
Query: 210 DSREHKS-AFKEPSRDHNKSSKESSKKPKENKPLKEEKIVPKMAFKEPKPMSKE 262
+SRE K+ + P +SS+++ K K ++EKI + + K +E
Sbjct: 676 NSREKKADRDQSPFSKIKQSSQDNELKSSMLKNKEDEKIRSSVEKENQKSKGQE 729
Score = 31.2 bits (69), Expect = 2.7
Identities = 38/183 (20%), Positives = 72/183 (39%), Gaps = 19/183 (10%)
Query: 329 DKSHVKMGKVKIESET-----SEKKKSTLPPFDDIVDPNDSDVEENISSKSDSEQPSPAS 383
D HV G+V E ++K + PF ++ + + + KS ++
Sbjct: 135 DGHHVVFGQVISGQEVVREIENQKTDAASKPFAEVRILSCGE----LIPKSKVKKEEKKR 190
Query: 384 SSSSSSSSFTPSQTRQQGPLRSIMKDLHSDDNEEESDEVEDNDNDSEMERPVNRGGSRSR 443
SSSSSS + S + +S SD ++ ES E + + R +R + +
Sbjct: 191 HKSSSSSSSSSSDSDSSSDSQS-----SSDSSDSESATEEKSKKRKKKHRKNSRKHKKEK 245
Query: 444 RVSLSDGSDSESSSASSPLHHEP-----PPPLLKTNNNQILEVKSPIKQSKSDKQIKNGE 498
+ + S S + L +P P + N+ L KSP K + +++ + E
Sbjct: 246 KKRKKSKKSASSESEAENLEAQPQSTVRPEEIPPIPENRFLMRKSPPKADEKERKNRERE 305
Query: 499 CDK 501
++
Sbjct: 306 RER 308
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 82.4 bits (202), Expect = 1e-15
Identities = 64/174 (36%), Positives = 86/174 (49%), Gaps = 21/174 (12%)
Query: 142 PNRSIHTSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFSKPHKLMK 201
P + SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS S +KP
Sbjct: 2600 PAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQAL 2659
Query: 202 EHKEKPSKDSREHKSAFKEPSRDHNKSSKESSKKPKENKPLKEEKIVPKMAFKEPKPMSK 261
P K P ++S ++ ++++ L + + +P P +
Sbjct: 2660 PKPASPKK---------PPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQ 2710
Query: 262 EPKPDSNLLTITSGQDKKAPSKRPPISDSEELSAKKRKKSSSEALFKSFSSAPP 315
+ + S+R DS S K+R+++ S + SS P
Sbjct: 2711 Q------------SSSSERGSRRGQRGDSRSPSHKRRRETPSPRPMRHRSSRSP 2752
Score = 64.7 bits (156), Expect = 2e-10
Identities = 55/171 (32%), Positives = 76/171 (44%), Gaps = 20/171 (11%)
Query: 153 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS-----------SSTSFSKPHKLMK 201
SSSSSSSSSSSSSSSSSSSSSSSSS SSSS S SS + P + ++
Sbjct: 2532 SSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVR 2591
Query: 202 EHK-EKPSKDSREHKSAFKEPSRDHNKSSKESSKKPKENKPLKEEKIVPKMAFKEPKPMS 260
E + +P+ R+ +S+ S + SS SS + + P
Sbjct: 2592 EGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSP 2651
Query: 261 KEPKPDSNLLTITSGQDKKAPSKRPPISDSEELSAKKRKKSSSEALFKSFS 311
+P P + K A K+PP + S +K S ++ S+S
Sbjct: 2652 AKPGPQA--------LPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYS 2694
Score = 64.3 bits (155), Expect = 3e-10
Identities = 74/276 (26%), Positives = 103/276 (37%), Gaps = 52/276 (18%)
Query: 138 AGGDPNRSIHTSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFSKPH 197
A G P+ + +S+ + S+ ++ + SSSSSSSSSSSSSSSSSSS+S S
Sbjct: 2498 APGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSS--- 2554
Query: 198 KLMKEHKEKPSKDSREHKSAFKEPSRDHNKSSKESSKKPKENKPLKEEKIVPKMAFKEPK 257
S + S E S P + + + P A KE
Sbjct: 2555 ------------------------SSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAV 2590
Query: 258 PMSKEPKPDSNLLTITSGQDKKAPSKRPPISDSEELSAKKRKKSSSEALFKSFSSAPPLI 317
+ P+P P+KR S S S+ SSS + S SS+
Sbjct: 2591 REGRPPEP--------------TPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2636
Query: 318 LTCSADKKQIKDKSHVKMGKVKIESETSEKK--------KSTLPPFDDIVDPNDSDVEEN 369
+ S+ S K G + S KK +S P D + D
Sbjct: 2637 SSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSP- 2695
Query: 370 ISSKSDSEQPSPASSSSSSSSSFTPSQTRQQGPLRS 405
+ + S QPSP SSSS S+ Q+G RS
Sbjct: 2696 VERRRPSPQPSPRDQQSSSSE--RGSRRGQRGDSRS 2729
Score = 55.1 bits (131), Expect = 2e-07
Identities = 70/327 (21%), Positives = 120/327 (36%), Gaps = 45/327 (13%)
Query: 120 EKLTFNNPTEDFRRKLLKAGGDPNRSIHTSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 179
+K +PT +RK D R + S++ + S + S+S+ S+SSS +S S S
Sbjct: 225 KKRKHRSPTPKSKRK----SKDKKRK-RSRSTTPAPKSRRAHRSTSADSASSSDTSRSRS 279
Query: 180 SSSSSSSSSSSTSFSKPHKLMKEHKEKPSKDSR-EHKSAFKEPSRDHNKSSKESSKKPKE 238
S+++ + +++ + P P+ R E + F EP S+++P
Sbjct: 280 RSAAAKTHTTALAGRSP---------SPASGRRGEGDAPFSEP-------GTTSTQRPSS 323
Query: 239 NKPLKEEKIVPKMAFKEPKPMSKEPKPDSNLLTITSGQDKKAPSKRPPISDSEELSAKKR 298
P+ A K+P P D + +DKK S P E S
Sbjct: 324 ----------PETATKQP----SSPYEDKD-------KDKKEKSATRPSPSPERSSTGPE 362
Query: 299 KKSSSEALFKSFSSAPPLILTCSADKKQIKDKSHVKMGKVKIESETSEKKKSTLPPFDDI 358
+ + L + +P + T ++ + S + + ++ EK +
Sbjct: 363 PPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSP 422
Query: 359 VDPNDSDVEENISSKSDSEQPSPASSSSSSSSSFTPSQTRQQGPLRSIMKDLHSDDNE-- 416
P + V + SS +S +P+PA S SS S+ R G + H+
Sbjct: 423 PSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMG 482
Query: 417 EESDEVEDNDNDSEMERPVNRGGSRSR 443
S P RG SRSR
Sbjct: 483 RSRSPATAKRGRSRSRTPTKRGHSRSR 509
Score = 55.1 bits (131), Expect = 2e-07
Identities = 90/372 (24%), Positives = 133/372 (35%), Gaps = 54/372 (14%)
Query: 141 DPNRSIHTSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS----SSSSSSSSSSSTSFSKP 196
DP+ + S+ SS SSS S + + SS+ S SS + + S S+S S P
Sbjct: 1366 DPSLDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSP 1425
Query: 197 HKLMKEHKEK-PSKDSREHKS-----AFKEPSRDHNKSS----KESSKKPKENKPLKEEK 246
MK+ + PS+ SR S PSR S K+ + P + +
Sbjct: 1426 E--MKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSS 1483
Query: 247 IVPKMAFKEPKPMSKEP-KPDSNLLTIT-----SGQDKKAPSK---RPPI------SDSE 291
PK + P+P S+ P P+ N +T SG + K R P+ S+
Sbjct: 1484 PEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQ 1543
Query: 292 ELSAK------KRKKSSSEALFKSFSSAPPLILTCSADKKQIKDKSHVKMGKVKIESETS 345
EL K +R +S S K+ + P + S ++ KS + + + S
Sbjct: 1544 ELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPE 1603
Query: 346 EKKK----------STLPPFDDIVDPNDSDVEENISSKSDSEQPSPASSSSSSSSSFTPS 395
K K S P P S S PSP SSS+ SS P
Sbjct: 1604 VKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPP 1663
Query: 396 QTRQQGPLRSIMKDLHSDDNEEESDEVEDNDNDSEMERPVNRGGSRSRRVSLSDGSDSES 455
++ R+ + S + S + R SRR S S S E+
Sbjct: 1664 KS------RTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRR-SRSASSSPET 1716
Query: 456 SSASSPLHHEPP 467
S + P H P
Sbjct: 1717 RSRTPPRHRRSP 1728
Score = 54.3 bits (129), Expect = 3e-07
Identities = 66/275 (24%), Positives = 96/275 (34%), Gaps = 43/275 (15%)
Query: 142 PNRSIHTSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSST---------- 191
P R + SSS + S +S S S+SS S SS S S SS +
Sbjct: 718 PQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRR 777
Query: 192 SFSKPHKLMKEHKEKPSKDSREHKSAFKEPSRDHNKSSKESSKKPKENKPLKEEKIVPKM 251
S S K+ + P + SR S K SR + S+ SS P + K +
Sbjct: 778 SLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSS 837
Query: 252 AFKEPKPMSKEPKPDSNLLTITSGQDKKAPSKRPPISDSEELSAKKRKKSSSEALFKSFS 311
+ PK S P ++ + + + P +R S + K R S S S
Sbjct: 838 SSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSR-----HSCS 892
Query: 312 SAPPLILTCSADKKQIKDKSHVKMGKVKIESETSEKKKSTLPPFDDIVDPNDSDVEENIS 371
+ P + S +Q +S KVK I+ P
Sbjct: 893 GSSPPRVKSSTPPRQSPSRSSSPQPKVKA-----------------IISPRQ-------R 928
Query: 372 SKSDSEQPSPASSSSSSSSSFTPSQTRQQGPLRSI 406
S S S PSP S +S TP ++R P ++
Sbjct: 929 SHSGSSSPSP----SRVTSRTTPRRSRSVSPCSNV 959
Score = 44.7 bits (104), Expect = 2e-04
Identities = 72/344 (20%), Positives = 128/344 (37%), Gaps = 46/344 (13%)
Query: 150 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFSKPHKLMKEHKEKPSK 209
+ S S SS + + + S S SSS S SSST S H + S+
Sbjct: 1614 AQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSR 1673
Query: 210 DSREHKSAFKEPSRDH-NKSSKESSKKPKENKPLKEEKIVPKMAFKEP-----KPMSKEP 263
S E K+ + P R ++SS E ++K + ++ + P+ + P P P
Sbjct: 1674 SSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSP 1733
Query: 264 KP------------DSNLLTITSGQDKKAPSKRPPISDSEELSAKKRKKSSSEALFKSFS 311
+P S+ T T+ + ++PS +P +++ K ++ +S S
Sbjct: 1734 EPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGS 1793
Query: 312 SAPPLILTCSADKKQIKDKSHV---KMGKVKIESETSEKKKSTLPPFDDIVDPNDSDVEE 368
S + S +++ + +S V + G S + +++S+ + +
Sbjct: 1794 SQ-----STSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTS 1848
Query: 369 NISSKSDSEQPSPASSSSSSSSSFTPSQTRQQGPLRSIMKDLHSDDNEEESDEVEDNDND 428
S+S + P+P S S +S T ++R + PL S
Sbjct: 1849 RKRSRSRT-SPAPWKRSRSRASPATHRRSRSRTPLIS-------------------RRRS 1888
Query: 429 SEMERPVNRGGSRSRRVSLSDGSDSESSSASSPLHHEPPPPLLK 472
PV+R SRSR S S +S S PP+ +
Sbjct: 1889 RSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTR 1932
Score = 43.9 bits (102), Expect = 4e-04
Identities = 69/281 (24%), Positives = 103/281 (36%), Gaps = 30/281 (10%)
Query: 137 KAGGDPNRSIHTSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFSKP 196
+ G +R+ S S S S S + S SSS + S +S S S S P
Sbjct: 688 RRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSP 747
Query: 197 HKLMKEHKEKPSKDSREHKSAFKEPSRDHNKSSKESSKKPKENKPLKEEKIVPKMAFKEP 256
+K SR +S S+ ++ S S P ++ + P+ +
Sbjct: 748 ------EMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRS---- 797
Query: 257 KPMSKEPKPDSNLLTITSGQDKKAPSKRPPISDSEELSAKKRKKSSSEALFKSFSSAPPL 316
+ S +PK S T + ++ S PP S+ S + SS K S PP
Sbjct: 798 RSGSSQPKAKSR----TPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVK--SGTPP- 850
Query: 317 ILTCSADKKQIKDKSHVKMGKVKIESETSEKKKSTLPPFDDIVDPNDSDVEENI-----S 371
S Q ++S + ES + KS P + V+ +
Sbjct: 851 -RQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSP 909
Query: 372 SKSDSEQP------SPASSSSSSSSSFTPSQ-TRQQGPLRS 405
S+S S QP SP S S SSS +PS+ T + P RS
Sbjct: 910 SRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRS 950
Score = 43.1 bits (100), Expect = 7e-04
Identities = 71/362 (19%), Positives = 131/362 (36%), Gaps = 38/362 (10%)
Query: 135 LLKAGGDPNRSIHTSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFS 194
L +G P + + SSS + + +S++ S+ +++ + + S ++++ + +S TS
Sbjct: 2311 LTGSGTPPTAANYPSSSRTPQAPASANLVGPRSAHATAPVNIAGSRTAAALAPASLTSAR 2370
Query: 195 KPHKLMKEHKEKPSK--DSREHKSAFKEPSRDHNKSSKESSKKPKENKPLKEEKIVPKMA 252
L + P + E S P S+ P +++ E P
Sbjct: 2371 MAPALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSR 2430
Query: 253 FKEPKPMSKEP----KPDSNLLTITSGQDKKAPSKRPPISDSEELSAKKRKKSSSEALFK 308
+ S P +P S + + S Q + ++ P++ S+ LS+ ++S A
Sbjct: 2431 MGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDH 2490
Query: 309 SFSSAPPLILTCSADKKQIKDKSHVKMGKVKIESETSEKKKSTLPPFDDIVDPNDSDVEE 368
+ + P H +G+ + T ++ S L + S
Sbjct: 2491 NGMLSVPA-----------PGVPHSDVGEPP--ASTGAQQPSALAALQPAKERRSSSSSS 2537
Query: 369 NISSKSDSEQPSPASSSSSSSSSF-------------------TPSQTRQQGPLRSIMKD 409
+ SS S S S +SSSSS SSS +P+ ++ +
Sbjct: 2538 SSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPE 2597
Query: 410 LHSDDNEEESDEVEDNDNDSEMERPVNRGGSRSRRVSLSDGSDSESSSASSPLHHEPPPP 469
+ S + + S + S S S S S S SSS+SSP +P P
Sbjct: 2598 PTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQ 2657
Query: 470 LL 471
L
Sbjct: 2658 AL 2659
Score = 40.4 bits (93), Expect = 0.004
Identities = 81/360 (22%), Positives = 133/360 (36%), Gaps = 27/360 (7%)
Query: 125 NNPTEDFRRKLLKAGGDPNRSIHTSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 184
N P+E + P + +SSS SS S + S +SSS S + + S
Sbjct: 392 NPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHR 451
Query: 185 SSSSSSTSFSKPH---KLMKEHKEKPSKDSREHKSAF-----KEPSRDHNKSSKESSKKP 236
SSS TS ++ H K K H PS+ +S + SR K S+ P
Sbjct: 452 EISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSP 511
Query: 237 KENKPLKEEKIVPKMAFKEPKPMSKEPKPDSNLLTITSGQDKKAPSKRPPISDSEELSAK 296
+ + ++ + + + S+ P+ + + + ++ S R S S + +
Sbjct: 512 QWRRSRSAQRW-GRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATR 570
Query: 297 KRKKSSSEALF-KSFSSAPPLILTCSADKKQIKDKSHVKMGKVKIESETSEKKKS-TLPP 354
R +S + A +S S P + S + + +S + + S T +++S T P
Sbjct: 571 GRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSP 630
Query: 355 FDDIVDPNDSDVEENISSKSDSEQPSPASSSSSS-------SSSFTPSQ----TRQQGPL 403
+ + S S +S S P+ S S S S TP++ +R + P
Sbjct: 631 ---VRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPA 687
Query: 404 RSIMKDLHSDDNEEESDEVEDNDNDSEMERPVNRG--GSRSRRVSLSDGSDSESSSASSP 461
R + S P RG GS S R + S S S S SSP
Sbjct: 688 RRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSP 747
Score = 39.7 bits (91), Expect = 0.007
Identities = 78/351 (22%), Positives = 116/351 (33%), Gaps = 28/351 (7%)
Query: 132 RRKLLKAGGDPNRSIHTSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSST 191
RR L + P + T S S SS + S + S SSSS S + S S
Sbjct: 776 RRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSH 835
Query: 192 SFSKPHKLMKEHKEKPSKDSREHKSAFKEPSRDHNKSSKESSKKP--KENKPLKEE---- 245
S S PH +K P + S A ++ +S ESS P K P +
Sbjct: 836 SSSSPHPKVKS-GTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGS 894
Query: 246 ---KIVPKMAFKEPKPMSKEPKPDSNLLTITSGQDKKAPSKRPPISDSEELSAKKRKKSS 302
++ ++ S P+P + I+ Q + S P S + +R +S
Sbjct: 895 SPPRVKSSTPPRQSPSRSSSPQPKVKAI-ISPRQRSHSGSSSPSPSRVTSRTTPRRSRSV 953
Query: 303 SEALFKSFSSAPPLILTCSADKKQIKDKSHVKMGKVKIESETSE-----KKKSTLPPFDD 357
S S+ +L + + VK +S + K K+ PP
Sbjct: 954 SPC-----SNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGPS 1008
Query: 358 IVDPNDSDVEENISSKSDSEQPSPAS-SSSSSSSSFTPSQTRQQGPLRSIMKDLHSDDNE 416
+ +E SK Q P S S + S TP G +K +
Sbjct: 1009 LSGSKSPCPQE--KSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPD 1066
Query: 417 EESDEVEDNDNDSEMERPVNRGGSRSRRVSLSDGSDSESSSASSPLHHEPP 467
SD S E P +S+ + G S SSS + L P
Sbjct: 1067 HRSDTSSPEVRQSHSESP----SLQSKSQTSPKGGRSRSSSPVTELASRSP 1113
Score = 37.7 bits (86), Expect = 0.028
Identities = 71/360 (19%), Positives = 130/360 (36%), Gaps = 31/360 (8%)
Query: 139 GGDPNRSIHTSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFSKPHK 198
G P S T SS S ++ S SS + S + SS SS T ++ +
Sbjct: 1646 GPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSR 1705
Query: 199 LMKEHKEKPSKDSREHKSAFKEPSRDHNKSSKESSKKPKENKPLKEEKIVPKMAFKEPKP 258
+ P SR + PS SS E ++K + ++ + P+ +
Sbjct: 1706 RSRSASSSPETRSRTPPRHRRSPS----VSSPEPAEKSRSSR-RRRSASSPRTKTTSRRG 1760
Query: 259 MSKEPKPDS-NLLTITSGQDKKAPSKRPPISDSEELSAKKRKKSSSEALF-------KSF 310
S PKP S ++K ++R S S + ++++R++S S + +
Sbjct: 1761 RSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGY 1820
Query: 311 SSAPPLILTCSADKKQIKDKSHVKMGKVKIESETSEKKKSTLPPFDDIVDPNDSDVEENI 370
S P A ++ + S + G+ + + ++ +S P S +
Sbjct: 1821 HSRSP------ARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSP----APWKRSRSRASP 1870
Query: 371 SSKSDSEQPSPASSSSSSSSSFTPSQTRQQGPLRSIMKDLHSDDNEEESDEVEDNDNDSE 430
++ S +P S S S +P R+ S+ + + + V + S
Sbjct: 1871 ATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTR----RRSRSRASPVSRRRSRSR 1926
Query: 431 MERPVNRGGSRSRRVSLSDGSDSESSSASSPLHHEPPPPLLKTNNNQILEVKSPIKQSKS 490
PV R SRSR + S S + + PP+ + + SPI + +S
Sbjct: 1927 TP-PVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSR---SRTSPITRRRS 1982
Score = 37.4 bits (85), Expect = 0.037
Identities = 61/288 (21%), Positives = 95/288 (32%), Gaps = 29/288 (10%)
Query: 207 PSKDSREHKSAFKEPSRDHNKSSKESSKKPKENKPLKEEKIVPKMAFKEPKPMSKEPKPD 266
P + +RE K EP + ++ + SS + K K++K + E +E K
Sbjct: 153 PQRRAREAKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKS 212
Query: 267 SNLLTITSGQDKKAPSKRPPISDSEELSAKKRKKSSSEALFKSFSSAPP---LILTCSAD 323
S S + K R P S+ S K++K S +S + AP + SAD
Sbjct: 213 SKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRS-----RSTTPAPKSRRAHRSTSAD 267
Query: 324 KKQIKDKSHVKMGKVKIESETSEKKKSTLPPFDDIVDPNDSDVEENISSKSDSEQPSPAS 383
D S + ++ T+ + P D+ E P +
Sbjct: 268 SASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSE------------PGT 315
Query: 384 SSSSSSSSFTPSQTRQQGPLRSIMKDLHSDDNEEESDEVEDNDNDSEMERPVNRGGSRSR 443
+S+ SS + + P KD S E + E P R
Sbjct: 316 TSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERH- 374
Query: 444 RVSLSDGSDSESSSASSPLHHEP-PPPLLKTNNNQILEVKSPIKQSKS 490
S A++PL EP PP + KSP K +S
Sbjct: 375 -------GGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQS 415
Score = 36.6 bits (83), Expect = 0.063
Identities = 71/337 (21%), Positives = 126/337 (37%), Gaps = 39/337 (11%)
Query: 132 RRKLLKAGGDPNRSIHTSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSST 191
RR+ ++ + R S S S+SSS + S + S S SS + S SS
Sbjct: 1687 RRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRR 1746
Query: 192 SFSKPH-----KLMKEHKEKPSKDSREHKSAFKEPS-----RDHNKSSKESSKKPKENKP 241
S S P + + KP R + +E + RD + SS+ +S++ + +
Sbjct: 1747 SASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRS-- 1804
Query: 242 LKEEKIVPKMAFKEPKPMSKEPKPDSNLLTITSGQDKKAPSKRPPISDSEELSA------ 295
+ V + S+ P + + TS + ++ S+ PP S S
Sbjct: 1805 -RSRSRVTRRRRGGSGYHSRSPARQES--SRTSSRRRRGRSRTPPTSRKRSRSRTSPAPW 1861
Query: 296 KKRKKSSSEALFKSFSSAPPLI-------LTCSADKKQIKDKSHV--KMGKVKIESETSE 346
K+ + +S A + S PLI T +++ + ++ V + + + +
Sbjct: 1862 KRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRR 1921
Query: 347 KKKSTLPPFDDIVDPNDSDVEENISSKSDSEQPSPASSSSSSSSSFTPSQTRQQGPLRSI 406
+ +S PP V S + + + P + S S TP TR++ RS
Sbjct: 1922 RSRSRTPP----VTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSR--TPPVTRRRS--RSR 1973
Query: 407 MKDLHSDDNEEESDEVEDNDNDSEMERPVNRGGSRSR 443
+ + + V + S PV R SRSR
Sbjct: 1974 TSPITRRRSRSRTSPVTRRRSRSRTS-PVTRRRSRSR 2009
Score = 35.0 bits (79), Expect = 0.18
Identities = 44/248 (17%), Positives = 93/248 (37%), Gaps = 10/248 (4%)
Query: 113 PVNHLRCEKLTFNNPTEDFRRKLLKAGGDPNRSIHTSSSSSSSSSSSSSSSSSSSSSSSS 172
P H R ++ P E R + R+ TS S S S S S
Sbjct: 1721 PPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRRE 1780
Query: 173 SSSSSSSSSSSSSSSSSSTSFSKPHKLMKEHKEKPSKDSREHKS-AFKEPSRDHNKSSKE 231
+ ++ S SS S+S + + + + +S A +E SR ++ +
Sbjct: 1781 KTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRG 1840
Query: 232 SSKKPKENKPLKEEKIVP---KMAFKEPKPMS-KEPKPDSNLLTITSGQDKKAP-SKRPP 286
S+ P ++ + P K + P + + + + L++ + + +P S+R
Sbjct: 1841 RSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRS 1900
Query: 287 ISDSEELSAKKRKKSSSEALFKSFSSAPPLILTCSADKKQIKDKSHVKMGKVKIESETSE 346
S + + R ++S + +S S PP+ + + + + + + + + T
Sbjct: 1901 RSRTSVTRRRSRSRASPVSRRRSRSRTPPV----TRRRSRSRTPTTRRRSRSRTPPVTRR 1956
Query: 347 KKKSTLPP 354
+ +S PP
Sbjct: 1957 RSRSRTPP 1964
Score = 34.3 bits (77), Expect = 0.31
Identities = 71/342 (20%), Positives = 133/342 (38%), Gaps = 39/342 (11%)
Query: 161 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFSKPHKLMKEHKEKPSKDSREHKSAFKE 220
S+S S S S S SSS + S++ + E KEK + +E +A
Sbjct: 1122 SASPMLKSGMSPEQSRFQSDSSSYPTVDSNSLLGQSRLETAESKEKMALPPQEDATA--S 1179
Query: 221 PSRDHNKSSKESSKKPKENKPLKEEKIVPKMAFKEPKPMSKEPKPDSNLLTITSGQDKKA 280
P R +K S P +++P E +V K + P P +S + K+
Sbjct: 1180 PPRQKDK----FSPFPVQDRP--ESSLVFKDTLRTP--------PRERSGAGSSPETKEQ 1225
Query: 281 PSKRPPISDSEELS--AKKRKKSSSEALFKSFSSAPPLILTCSADKKQIKDKSHVKMGKV 338
S P S EEL +K ++ + + L S + + +++++ V +
Sbjct: 1226 NSALPTSSQDEELMEVVEKSEEPAGQILSHLSSELKEMSTSNFESSPEVEERPAVSLTLD 1285
Query: 339 KIESETSEKKKSTLPPFDDIVDPNDSDVEENISSKSDSEQPSPASSSSSSSSSFTPSQTR 398
+ +S+ S + P+ S + +S+ SP +S S P + R
Sbjct: 1286 QSQSQASLEAVEVPSMASSWGGPHFSPEHKELSN-------SPLRENSFGS----PLEFR 1334
Query: 399 QQGPLRSIMKDLHSDDNEEE-----SDEVEDNDNDSEMERPVNRGGSRSRRVS---LSDG 450
GPL + M S + +E+ +++E + + E+ G S +S +
Sbjct: 1335 NSGPLGTEMNTGFSSEVKEDLNGPFLNQLETDPSLDMKEQSTRSSGHSSSELSPDAVEKA 1394
Query: 451 SDSESSSASSPLHHEPP--PPLLKTNNNQILEVKSPIKQSKS 490
S + S SSP+ P P ++++ E+K + ++ S
Sbjct: 1395 GMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPS 1436
Score = 32.7 bits (73), Expect = 0.92
Identities = 70/373 (18%), Positives = 132/373 (35%), Gaps = 69/373 (18%)
Query: 146 IHTSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFSKPHKLMKEHKE 205
++ + S ++++ + +S +S+ + + S ++ +S S+ S S P +
Sbjct: 2350 VNIAGSRTAAALAPASLTSARMAPALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRT 2409
Query: 206 KPSKDSREHKSAFKEPSRDHN--KSSKESSKKPKENKPLKEEKIVPKMAFKEPKPMSKEP 263
PS S+ ++ + PS ++ +S P +++P VP + + + +
Sbjct: 2410 PPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSP---VPSAFSDQSRCLIAQT 2466
Query: 264 KPDSNLLTITSGQDKKAPSK---------------------RPPISDSEELS-------- 294
P + +++SG S PP S +
Sbjct: 2467 TPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQP 2526
Query: 295 AKKRKKSSSEALFKSFSSAPPLILTCSADKKQIKDKSHVKMGKVKIESETSEKKKSTLPP 354
AK+R+ SSS + S SS+ + S+ S +S+ + S+LP
Sbjct: 2527 AKERRSSSSSSSSSSSSSSSSSSSSSSSSSG----------------SSSSDSEGSSLPV 2570
Query: 355 FDDIV---DPNDSDVEENISSKSDSEQPSPA---------SSSSSSSSSFTPSQTRQQGP 402
++ P+ + + + +P+PA SSSSSSSSS + S +
Sbjct: 2571 QPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSS 2630
Query: 403 LRSIMKDLHSDDNEEESDEVEDNDNDSEMERPVN-------RGGSRSRRVSLSDGSDSES 455
S S + S + +P + SRS R + DS S
Sbjct: 2631 SSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRS 2690
Query: 456 SSASSPLHHEPPP 468
S S P P
Sbjct: 2691 LSYSPVERRRPSP 2703
Score = 32.3 bits (72), Expect = 1.2
Identities = 70/359 (19%), Positives = 133/359 (37%), Gaps = 52/359 (14%)
Query: 135 LLKAGGDPNRSIHTSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFS 194
+LK+G P +S S SSS + S+S S ++ S + +++S
Sbjct: 1126 MLKSGMSPEQSRFQSDSSSYPTVDSNSLLGQSRLETAESKEKMALPPQEDATAS------ 1179
Query: 195 KPHKLMKEHKEKPSKDSREHKSAFKEPSR--DHNKSSKESSKKPKENKPLKEEKIVPKMA 252
P + + P +D E FK+ R +S SS + KE + +P +
Sbjct: 1180 -PPRQKDKFSPFPVQDRPESSLVFKDTLRTPPRERSGAGSSPETKE-----QNSALPTSS 1233
Query: 253 FKEP--KPMSKEPKPDSNLLTITSGQDKKAPSKR----PPISDSEELSA---KKRKKSSS 303
E + + K +P +L+ S + K+ + P + + +S + + ++S
Sbjct: 1234 QDEELMEVVEKSEEPAGQILSHLSSELKEMSTSNFESSPEVEERPAVSLTLDQSQSQASL 1293
Query: 304 EAL-----------------FKSFSSAPPLILTCSADKKQIKDKSHVKMGKVKIESETSE 346
EA+ K S++P L ++ ++ ++ +G +SE
Sbjct: 1294 EAVEVPSMASSWGGPHFSPEHKELSNSP---LRENSFGSPLEFRNSGPLGTEMNTGFSSE 1350
Query: 347 KKKSTLPPFDDIVDPNDSDVEENISSKSDSEQPSPASSSSSSSSSFTPS-QTRQQGPLRS 405
K+ PF N + + ++ K S + S SSS S + + + Q
Sbjct: 1351 VKEDLNGPF-----LNQLETDPSLDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQSISSP 1405
Query: 406 IMKDLHSDDNEEESDEVEDNDNDSEMERPVNRGGSRSRRVSLSDGSDS---ESSSASSP 461
++ + + E S + + R +R L DGS + S S SSP
Sbjct: 1406 VLDAVPRTPSRERSSSASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSP 1464
Score = 30.8 bits (68), Expect = 3.5
Identities = 48/236 (20%), Positives = 92/236 (38%), Gaps = 17/236 (7%)
Query: 234 KKPKENKPLKEEKIVPKMAFKEPKPMSKEPKPDSNLLT--ITSGQDKKAPSKRPPISDSE 291
K+ E + L+ E+++ + ++E + K LL + G ++ P +RP ++++
Sbjct: 63 KRRVELRCLELEEMMEEQGYEEQQIQEKVATFRLMLLEKDVNPGGKEETPGQRPAVTETH 122
Query: 292 ELSAKKRKKSSSEALFKSFSSAPPLILTCSAD-KKQIKDKSHVKMGKVKIESETSEKKKS 350
+L+ KK +E L +F + + S D +++ ++ K S E S
Sbjct: 123 QLAELNEKK--NERLRAAFGISDSYVDGSSFDPQRRAREAKQPAPEPPKPYSLVRESSSS 180
Query: 351 TLPPFDDIVDPNDSDVEENISSKSDSEQPSPASSSSSSSSSFTPSQTRQQGPLRSIMKDL 410
P P ++ SE SP SS + R + +
Sbjct: 181 RSP------TPKQKKKKKKKDRGRRSESSSPRRERKKSSKK---KKHRSESESKKRKHRS 231
Query: 411 HSDDNEEESDEVEDNDNDSEMERPVNRGGSRSR---RVSLSDGSDSESSSASSPLH 463
+ ++ +S + + + S P +R RS S SD S S S SA++ H
Sbjct: 232 PTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTH 287
>gi|125656165 THO complex 2 [Homo sapiens]
Length = 1593
Score = 77.0 bits (188), Expect = 4e-14
Identities = 80/340 (23%), Positives = 140/340 (41%), Gaps = 42/340 (12%)
Query: 139 GGDPNRSIHTSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFSKPHK 198
GG P+ S S+S S SS+ + S S + + +SS++ +SS+ S S +K
Sbjct: 1205 GGGPSSSSIGSASKSDESSTEETDKSRERSQCGVKAVNKASSTTPKGNSSNGNSGSNSNK 1264
Query: 199 LMKEH-KEKPSKDSREHKSAFKEPSRDHNKSSKESSKKPKENKPLKEEKIVPKMAFKEPK 257
+KE+ KEK + +E K + + K+ +KPKE +P K+EK +E K
Sbjct: 1265 AVKENDKEKGKEKEKEKKEKTPATTPEARVLGKDGKEKPKEERPNKDEKA------RETK 1318
Query: 258 PMSKEPKPDSNLLTITSGQDKKAPSKRPPISDSEELSAKKRKKSSSEALFKSFSSAPPLI 317
+ PK D + K + + ++E S ++R++ + + +
Sbjct: 1319 --ERTPKSDKEKEKFKKEEKAKDEKFKTTVPNAESKSTQEREREKEPSRERDIA------ 1370
Query: 318 LTCSADKKQIKDKSHVKMGKVKIESETSEKKKSTLPPFDDIVDPNDSDVEENISSKSDSE 377
K++K K +VK G+ ++ S KS +P DI +P I +
Sbjct: 1371 -------KEMKSKENVKGGE---KTPVSGSLKSPVPR-SDIPEPEREQKRRKIDT----- 1414
Query: 378 QPSPASSSSSSSSSFTPSQTRQQGPLRSIMKDLHSDDNEEESDEVEDNDNDSEMERPVNR 437
PSP+ SS+ S ++ + + L S E E D+ +D D E R +
Sbjct: 1415 HPSPSHSSTVKDSLIELKESSAKLYINHTPPPL-SKSKEREMDK-KDLDKSRERSREREK 1472
Query: 438 GGSRSRRVSLSDGSDSESSSASSPLHHEPPPPLLKTNNNQ 477
+ R+ D S+++ E PP L K +
Sbjct: 1473 KDEKDRKERKRDHSNND---------REVPPDLTKRRKEE 1503
Score = 37.4 bits (85), Expect = 0.037
Identities = 36/172 (20%), Positives = 65/172 (37%), Gaps = 4/172 (2%)
Query: 178 SSSSSSSSSSSSSTSFSKPHKLMKEHKEKPSKDSREHKSAFKEPSRDHNKSSKESSKKPK 237
S S SS+ S KL H P S+E + K+ + +S + K K
Sbjct: 1417 SPSHSSTVKDSLIELKESSAKLYINHTPPPLSKSKEREMDKKDLDKSRERSREREKKDEK 1476
Query: 238 ENKPLKEEKIVPKMAFKEPKPMSKEPKPDSNLLTITSGQDKKAPSKRPPISDSEELSAKK 297
+ K K + + P ++K K ++ + ++ + K P + ++ K
Sbjct: 1477 DRKERKRDH--SNNDREVPPDLTKRRKEENGTMGVS--KHKSESPCESPYPNEKDKEKNK 1532
Query: 298 RKKSSSEALFKSFSSAPPLILTCSADKKQIKDKSHVKMGKVKIESETSEKKK 349
K S E SF S ++ K+ DK ++ + + S E+KK
Sbjct: 1533 SKSSGKEKGSDSFKSEKMDKISSGGKKESRHDKEKIEKKEKRDSSGGKEEKK 1584
>gi|91206454 hypothetical protein LOC257415 isoform 2 [Homo sapiens]
Length = 237
Score = 75.5 bits (184), Expect = 1e-13
Identities = 55/165 (33%), Positives = 76/165 (46%), Gaps = 2/165 (1%)
Query: 150 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFSKPHKLMKEHKEKPSK 209
S S SSS S SSSSSSSS SSSSSS S K K K+ K + K
Sbjct: 72 SGSESSSKKRQRKKKEKKKSGRYSSSSSSSSDSSSSSSDSEDEDKKQGKRRKKKKNRSHK 131
Query: 210 DSREHKSAFKEPSRDHNKSSKESSKKPKENKPLKEEKIVPKMAFKEPKPMSKEPKPDSNL 269
S S + S+D K K+S ++ K +K KM + E KP+S E +S
Sbjct: 132 SSESSMSETESDSKDSLKKKKKSKDGTEKEKDIKGLSKKRKM-YSEDKPLSSESLSESEY 190
Query: 270 LTITSGQDKKAPSKRPPISDSEELSAKKRKKSSSEALFKSFSSAP 314
+ + KK+ +R ++ + KK KK S + K+ SS+P
Sbjct: 191 IEEVRAKKKKSSEEREKATEKTK-KKKKHKKHSKKKKKKAASSSP 234
Score = 42.4 bits (98), Expect = 0.001
Identities = 37/177 (20%), Positives = 76/177 (42%), Gaps = 12/177 (6%)
Query: 324 KKQIKDKSHVKMGKVKIESETSEKKKSTLPPF-DDIVDPNDSDVEENISSKSDSEQP--- 379
K+Q++ K + E + +E K L + ++ ++S ++ K + ++
Sbjct: 35 KEQLEKKKKGSKALAEFEEKMNENWKKELEKHREKLLSGSESSSKKRQRKKKEKKKSGRY 94
Query: 380 ---SPASSSSSSSSSFTPSQTRQQGPLRSIMKDLHSDDNEEESDEVEDNDNDSEMERPVN 436
S +SS SSSSSS + + ++QG R K+ +E E E + DS ++ +
Sbjct: 95 SSSSSSSSDSSSSSSDSEDEDKKQGKRRKKKKNRSHKSSESSMSETESDSKDSLKKKKKS 154
Query: 437 RGGSRSRRVSLSDGSDSESSSASSPLHHEPPPPLLKTNNNQILEVKSPIKQSKSDKQ 493
+ G+ + + S PL E + + I EV++ K+S +++
Sbjct: 155 KDGTEKEKDIKGLSKKRKMYSEDKPLSSES-----LSESEYIEEVRAKKKKSSEERE 206
Score = 32.7 bits (73), Expect = 0.92
Identities = 52/246 (21%), Positives = 93/246 (37%), Gaps = 24/246 (9%)
Query: 184 SSSSSSSTSFSKPHKLMKEHKEKPSKDSREHKSAFKEPSRDHNKSSKESSKKPKENKPLK 243
SS + ++P +E KE+ K + K A E N++ K+ +K +E K L
Sbjct: 15 SSGPTIQDYLNRPRPTWEEVKEQLEKKKKGSK-ALAEFEEKMNENWKKELEKHRE-KLLS 72
Query: 244 EEKIVPKMAFKEPKPMSKEPKPDSNLLTITSGQDKKAPSKRPPISDSEELSAKKRKKSSS 303
+ K ++ K K + S+ +S D + S D ++ +K+KK+ S
Sbjct: 73 GSESSSKKRQRKKKEKKKSGRYSSSS---SSSSDSSSSSSDSEDEDKKQGKRRKKKKNRS 129
Query: 304 EALFKSFSSAPPLILTCSADKKQIKDKSHVKMGKVKIESETSEKKKSTLPPFDDIVDPND 363
SS + T S K +K K K G K + KK +
Sbjct: 130 HK-----SSESSMSETESDSKDSLKKKKKSKDGTEKEKDIKGLSKKRKM---------YS 175
Query: 364 SDVEENISSKSDSEQPSPASSSSSSSSSFTPSQTRQQGPLRSIMKDLHSDDNEEESDEVE 423
D + S S+SE + S S+ R++ ++ K H ++++ +
Sbjct: 176 EDKPLSSESLSESEYIEEVRAKKKKS-----SEEREKATEKTKKKKKHKKHSKKKKKKAA 230
Query: 424 DNDNDS 429
+ DS
Sbjct: 231 SSSPDS 236
>gi|91206456 hypothetical protein LOC257415 isoform 1 [Homo sapiens]
Length = 247
Score = 75.5 bits (184), Expect = 1e-13
Identities = 55/165 (33%), Positives = 76/165 (46%), Gaps = 2/165 (1%)
Query: 150 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFSKPHKLMKEHKEKPSK 209
S S SSS S SSSSSSSS SSSSSS S K K K+ K + K
Sbjct: 82 SGSESSSKKRQRKKKEKKKSGRYSSSSSSSSDSSSSSSDSEDEDKKQGKRRKKKKNRSHK 141
Query: 210 DSREHKSAFKEPSRDHNKSSKESSKKPKENKPLKEEKIVPKMAFKEPKPMSKEPKPDSNL 269
S S + S+D K K+S ++ K +K KM + E KP+S E +S
Sbjct: 142 SSESSMSETESDSKDSLKKKKKSKDGTEKEKDIKGLSKKRKM-YSEDKPLSSESLSESEY 200
Query: 270 LTITSGQDKKAPSKRPPISDSEELSAKKRKKSSSEALFKSFSSAP 314
+ + KK+ +R ++ + KK KK S + K+ SS+P
Sbjct: 201 IEEVRAKKKKSSEEREKATEKTK-KKKKHKKHSKKKKKKAASSSP 244
Score = 42.4 bits (98), Expect = 0.001
Identities = 37/177 (20%), Positives = 76/177 (42%), Gaps = 12/177 (6%)
Query: 324 KKQIKDKSHVKMGKVKIESETSEKKKSTLPPF-DDIVDPNDSDVEENISSKSDSEQP--- 379
K+Q++ K + E + +E K L + ++ ++S ++ K + ++
Sbjct: 45 KEQLEKKKKGSKALAEFEEKMNENWKKELEKHREKLLSGSESSSKKRQRKKKEKKKSGRY 104
Query: 380 ---SPASSSSSSSSSFTPSQTRQQGPLRSIMKDLHSDDNEEESDEVEDNDNDSEMERPVN 436
S +SS SSSSSS + + ++QG R K+ +E E E + DS ++ +
Sbjct: 105 SSSSSSSSDSSSSSSDSEDEDKKQGKRRKKKKNRSHKSSESSMSETESDSKDSLKKKKKS 164
Query: 437 RGGSRSRRVSLSDGSDSESSSASSPLHHEPPPPLLKTNNNQILEVKSPIKQSKSDKQ 493
+ G+ + + S PL E + + I EV++ K+S +++
Sbjct: 165 KDGTEKEKDIKGLSKKRKMYSEDKPLSSES-----LSESEYIEEVRAKKKKSSEERE 216
Score = 32.7 bits (73), Expect = 0.92
Identities = 52/246 (21%), Positives = 93/246 (37%), Gaps = 24/246 (9%)
Query: 184 SSSSSSSTSFSKPHKLMKEHKEKPSKDSREHKSAFKEPSRDHNKSSKESSKKPKENKPLK 243
SS + ++P +E KE+ K + K A E N++ K+ +K +E K L
Sbjct: 25 SSGPTIQDYLNRPRPTWEEVKEQLEKKKKGSK-ALAEFEEKMNENWKKELEKHRE-KLLS 82
Query: 244 EEKIVPKMAFKEPKPMSKEPKPDSNLLTITSGQDKKAPSKRPPISDSEELSAKKRKKSSS 303
+ K ++ K K + S+ +S D + S D ++ +K+KK+ S
Sbjct: 83 GSESSSKKRQRKKKEKKKSGRYSSSS---SSSSDSSSSSSDSEDEDKKQGKRRKKKKNRS 139
Query: 304 EALFKSFSSAPPLILTCSADKKQIKDKSHVKMGKVKIESETSEKKKSTLPPFDDIVDPND 363
SS + T S K +K K K G K + KK +
Sbjct: 140 HK-----SSESSMSETESDSKDSLKKKKKSKDGTEKEKDIKGLSKKRKM---------YS 185
Query: 364 SDVEENISSKSDSEQPSPASSSSSSSSSFTPSQTRQQGPLRSIMKDLHSDDNEEESDEVE 423
D + S S+SE + S S+ R++ ++ K H ++++ +
Sbjct: 186 EDKPLSSESLSESEYIEEVRAKKKKS-----SEEREKATEKTKKKKKHKKHSKKKKKKAA 240
Query: 424 DNDNDS 429
+ DS
Sbjct: 241 SSSPDS 246
>gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1
[Homo sapiens]
Length = 651
Score = 73.9 bits (180), Expect = 4e-13
Identities = 91/415 (21%), Positives = 170/415 (40%), Gaps = 37/415 (8%)
Query: 90 KNKEEPRKVRFDYDLFLHLEGHPPVNHLRCEKLTFNNPTEDFRRK-------LLKAGGDP 142
K+K++ + + FLH + +P + R + T N+P + + L+ G
Sbjct: 198 KDKKDSKNSKKTNTEFLHTKNNPKKDLKRSK--TSNDPISEICSENSLNVDFLMLVGQSD 255
Query: 143 NRSIHTSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFSKPHKLMKE 202
+ SI+ + + S ++S + S + + + ++ SS + S S K K +K+
Sbjct: 256 DESINFDAWLRNYSQNNSKNYSLKYTKYTKKDTKKNAKKSSDAESEDSKDAKKDSKKVKK 315
Query: 203 H-----KEKPSKDSREHKSAFKEPSRDHNKSSKESSKKPKENKPLKEEKIVPKMAFKEPK 257
+ K+K K E A S+D K +K+ KK K++ K+ K P+ E
Sbjct: 316 NVKKDDKKKDVKKDTESTDAESGDSKDERKDTKKDKKKLKKDDKKKDTKKYPESTDTESG 375
Query: 258 PMSKEPKPDSNLLTITSGQDKKAPSKRPPIS-DSE-----ELSAKKRKKSSSEALFKSFS 311
NL + DKK +K+ S DSE + S K KK ++ +
Sbjct: 376 DAKDARNDSRNLKKASKNDDKKKDAKKITFSTDSESELESKESQKDEKKDKKDSKTDNKK 435
Query: 312 SAPPLILTCSAD-------KKQIKDKSHVKMGKVKIESETSEKK--KSTLPPFDDIVDPN 362
S + AD KK KD+ K K + + KK +ST D + +
Sbjct: 436 SVKNDEESTDADSEPKGDSKKGKKDEKKGKKDSKKDDKKKDAKKNAESTEMESDLELKKD 495
Query: 363 DSDVEENISSKSDSEQPSPASSSSS------SSSSFTPSQTRQQGPLRSIMKDLHSDDNE 416
+E SK D ++ + + S+ SS + + T+ +G + L+ +
Sbjct: 496 KKHSKEKKGSKKDIKKDARKDTESTDAEFDESSKTGFKTSTKIKGSDTESEESLYKPGAK 555
Query: 417 EESDEVEDNDNDSEMERPVNRGGSR--SRRVSLSDGSDSESSSASSPLHHEPPPP 469
++ DE + +S+ME ++ G R S++ + ++ + S+ P +PP P
Sbjct: 556 KKIDESDGTSANSKMEGLESKRGFRMSSKKTTFNEKGEKASTGRVPPSREKPPLP 610
Score = 55.1 bits (131), Expect = 2e-07
Identities = 82/425 (19%), Positives = 143/425 (33%), Gaps = 59/425 (13%)
Query: 113 PVNHLRCEKLTFNNPTEDFRRKLLKAGGDPNR--------SIHTSSSSSSSSSSSSSSSS 164
P HL K ++++ + GG P + S T+ S + +
Sbjct: 99 PFRHLYTSKTHLKKA--EYKKSKDEKGGTPLKKDSKKKGGSYATNPESKQIVEEKTKRQN 156
Query: 165 SSSSSSSSSSSSSSSSSSSSSSSSSSTSFSKPHKLMKEHKEKPSKDSREHKSAFKEPSRD 224
+ + SS + S S SSS ++ + K +K KDS+ K E
Sbjct: 157 EADKTPLKSSHENEQSKKSKSSSETNPESQNSKTVSKNCSQKDKKDSKNSKKTNTEFLHT 216
Query: 225 HNKSSKESSKKPKENKPLKE---------------------------------EKIVPKM 251
N K+ + N P+ E +
Sbjct: 217 KNNPKKDLKRSKTSNDPISEICSENSLNVDFLMLVGQSDDESINFDAWLRNYSQNNSKNY 276
Query: 252 AFKEPKPMSKEPKPDSNLLTITSGQDKKAPSKRPPISDSEELSAKKRKKSSSEALFKSFS 311
+ K K K+ K ++ + +D K K DS+++ K KK + K +
Sbjct: 277 SLKYTKYTKKDTKKNAKKSSDAESEDSKDAKK-----DSKKVK-KNVKKDDKKKDVKKDT 330
Query: 312 SAPPLILTCSADKKQIKDKSHVKMGKVKIESETSEKKKSTLPPFDDIVDP-NDSDVEENI 370
+ S D+++ K K+ K + +T + +ST D D NDS +
Sbjct: 331 ESTDAESGDSKDERKDTKKDKKKLKKDDKKKDTKKYPESTDTESGDAKDARNDSRNLKKA 390
Query: 371 SSKSDSEQPSPASSSSSSSSSFTPSQTRQQGPLRSIMKDLHSDDNEEESDEVEDNDNDSE 430
S D ++ + + S+ S S S+ Q+ + KD +D+ + ++ E D DSE
Sbjct: 391 SKNDDKKKDAKKITFSTDSESELESKESQKDEKKD-KKDSKTDNKKSVKNDEESTDADSE 449
Query: 431 MERPVNRGGSRSRRVSLSDGSDSESSSASSPLHHEPPPPLLKTNNNQILEVKSPIKQSKS 490
+ +G ++ D + A T LE+K K SK
Sbjct: 450 PKGDSKKGKKDEKKGKKDSKKDDKKKDAKKNAE--------STEMESDLELKKDKKHSKE 501
Query: 491 DKQIK 495
K K
Sbjct: 502 KKGSK 506
Score = 39.3 bits (90), Expect = 0.010
Identities = 65/322 (20%), Positives = 120/322 (37%), Gaps = 32/322 (9%)
Query: 145 SIHTSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFSKPHKLMKEHK 204
+I T +S S SS S + + + ++ S S + ++ K E
Sbjct: 10 NIRTYDNSIPISESSRKSWNQKHFALTFPKPLQRGTNDKSRPLKSQITVTRHDKRKLEEG 69
Query: 205 EKPSKDSREHK------------SAFKEPSRDHNKSSKESSKKPKENKPLKEEKIVPKMA 252
+KP+ H +A ++ H +SK KK + K E+ P
Sbjct: 70 QKPAHKWIRHSFRKILQWPPIYTAAREQTPFRHLYTSKTHLKKAEYKKSKDEKGGTPLKK 129
Query: 253 FKEPKPMSKEPKPDSNLLTITSGQDKKAPSKRPPISDSEELSAKKRKKSSSEALFKSFSS 312
+ K S P+S + + + K P S E +KK KSSSE +S +S
Sbjct: 130 DSKKKGGSYATNPESKQIVEEKTKRQNEADKTPLKSSHENEQSKK-SKSSSETNPESQNS 188
Query: 313 APPLILTCSADKKQIKDKSHVKMGKVKIESETSEKK-----KSTLPPFDDIVDPNDSDVE 367
DKK K+ K + ++ + KK K++ P +I N +V+
Sbjct: 189 KTVSKNCSQKDKKDSKNSK--KTNTEFLHTKNNPKKDLKRSKTSNDPISEICSENSLNVD 246
Query: 368 -ENISSKSDSE-----------QPSPASSSSSSSSSFTPSQTRQQGPLRSIMKDLHSDDN 415
+ +SD E + + + S + +T T++ S + S D
Sbjct: 247 FLMLVGQSDDESINFDAWLRNYSQNNSKNYSLKYTKYTKKDTKKNAKKSSDAESEDSKDA 306
Query: 416 EEESDEVEDNDNDSEMERPVNR 437
+++S +V+ N + ++ V +
Sbjct: 307 KKDSKKVKKNVKKDDKKKDVKK 328
>gi|33356174 pinin, desmosome associated protein [Homo sapiens]
Length = 717
Score = 72.8 bits (177), Expect = 8e-13
Identities = 52/131 (39%), Positives = 68/131 (51%), Gaps = 6/131 (4%)
Query: 137 KAGGDPNRSIHTSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFSKP 196
K +RS +SSSSSSS+SSSS SSSSS SSSS SSSSSSSS+S SSS SS+S S
Sbjct: 569 KTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSSSTSGSSSRDSSSSTSSS 628
Query: 197 HKLMKEHKEKPSKDSREHKSAFKEPSRD------HNKSSKESSKKPKENKPLKEEKIVPK 250
+ + + R+H+ + RD +KSSK S + + K + K
Sbjct: 629 SESRSRSRGRGHNRDRKHRRSVDRKRRDTSGLERSHKSSKGGSSRDTKGSKDKNSRSDRK 688
Query: 251 MAFKEPKPMSK 261
+ E K
Sbjct: 689 RSISESSRSGK 699
Score = 72.0 bits (175), Expect = 1e-12
Identities = 54/147 (36%), Positives = 78/147 (53%), Gaps = 9/147 (6%)
Query: 126 NPTEDFRRKLLKAGGDPNRSIHTSSSSSSSSSSSSS-SSSSSSSSSSSSSSSSSSSSSSS 184
N T R + + + S +SS SSSSS SSSS SSSSSSSS+S SSS SSSS+SS
Sbjct: 568 NKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSSSTSGSSSRDSSSSTSS 627
Query: 185 SSSSSSTSFSKPHKLMKEHK---EKPSKDS----REHKSAFKEPSRDHNKSSKESSKKPK 237
SS S S S + H ++H+ ++ +D+ R HKS+ SRD K SK+ + +
Sbjct: 628 SSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGLERSHKSSKGGSSRD-TKGSKDKNSRSD 686
Query: 238 ENKPLKEEKIVPKMAFKEPKPMSKEPK 264
+ + E K + + + + K
Sbjct: 687 RKRSISESSRSGKRSSRSERDRKSDRK 713
Score = 67.0 bits (162), Expect = 4e-11
Identities = 60/182 (32%), Positives = 84/182 (46%), Gaps = 14/182 (7%)
Query: 122 LTFNNPTEDFRRKLLKAGGDPNRSIHTSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 181
LT + ++ + ++ G S S SSSSSSSSSSS+SSSS SSSSS SSSS S
Sbjct: 546 LTVHPESKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRS 605
Query: 182 SSSSSSSSSTSFSKPHKLMKEHKEKPSKDSREHKSAFKEPSRDHNKSSKES---SKKPKE 238
SSSSSSS+S S S ++ S S +S + R HN+ K +K ++
Sbjct: 606 SSSSSSSTSGSSS---------RDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRD 656
Query: 239 NKPLKEEKIVPKMAFKEPKPMSKEPKPDSNLLTITSGQDKKAPSKRPPISDSEELSAKKR 298
L+ K SK+ S+ S + KR S+ + S +K
Sbjct: 657 TSGLERSHKSSKGGSSRDTKGSKDKNSRSDRKRSIS--ESSRSGKRSSRSERDRKSDRKD 714
Query: 299 KK 300
K+
Sbjct: 715 KR 716
Score = 55.8 bits (133), Expect = 1e-07
Identities = 54/190 (28%), Positives = 80/190 (42%), Gaps = 17/190 (8%)
Query: 116 HLRCEKLTFNNPTEDFRRKLLKAGGDPNRSIHTSSSSSSSSSSSSSSSSSSSSSSSSSSS 175
HL E+ F P E KL + +P ++H S S + + S S + + +S S S S
Sbjct: 522 HLLPERKDF--PVESV--KLTEVPVEPVLTVHPESKSKTKTRSRSRGRARNKTSKSRSRS 577
Query: 176 SSSSSSSSSSSSSSSTSFSKPHKLMKEHKEKPSKDSREHKSAFKEPSRDHNKSSKESSKK 235
SSSSSSSSSS+SSSS S S S + S S + S+ S+
Sbjct: 578 SSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSSSTSGSSSRDSSSSTSSSSESRSRSRG 637
Query: 236 PKENKPLKEEKIVPKMAFKEPKPMSKEPKPDSNLLTITSGQDKKAPSKRPPISDSEELSA 295
N+ K + V + + D++ L S + K S R ++ S
Sbjct: 638 RGHNRDRKHRRSVDR------------KRRDTSGLE-RSHKSSKGGSSRDTKGSKDKNSR 684
Query: 296 KKRKKSSSEA 305
RK+S SE+
Sbjct: 685 SDRKRSISES 694
Score = 35.4 bits (80), Expect = 0.14
Identities = 52/267 (19%), Positives = 92/267 (34%), Gaps = 25/267 (9%)
Query: 201 KEHKEKPSKDSREHKSAFKEP---SRDHNKSSKESSKKPKENKPLKEEKIVPKMAFKEPK 257
KE +EK K+S +P S+ + +S + P + E + +A +P
Sbjct: 456 KESEEKEEKESEPQPEPVAQPQPQSQPQLQLQSQSQPVLQSQPPSQPEDL--SLAVLQPT 513
Query: 258 PMSKEPK----PDSNLLTITSGQDKKAPSKRPPISDSEELSAKKRKKSSSEALFKSFSSA 313
P + + P+ + S + + P + P ++ E +K + +S S
Sbjct: 514 PQVTQEQGHLLPERKDFPVESVKLTEVPVE-PVLTVHPESKSKTKTRSRSRG-------- 564
Query: 314 PPLILTCSADKKQIKDKSHVKMGKVKIESETSEKKKSTLPPFDDIVDPNDSDVEENISSK 373
A K K +S S TS S+ + S S
Sbjct: 565 -------RARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSSSTSGSS 617
Query: 374 SDSEQPSPASSSSSSSSSFTPSQTRQQGPLRSIMKDLHSDDNEEESDEVEDNDNDSEMER 433
S S +SSS S S S R + RS+ + E S + + + +
Sbjct: 618 SRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGLERSHKSSKGGSSRDTKG 677
Query: 434 PVNRGGSRSRRVSLSDGSDSESSSASS 460
++ R+ S+S+ S S S+ S
Sbjct: 678 SKDKNSRSDRKRSISESSRSGKRSSRS 704
Score = 32.3 bits (72), Expect = 1.2
Identities = 60/286 (20%), Positives = 120/286 (41%), Gaps = 55/286 (19%)
Query: 198 KLMKEHKEKPSKDSREHKSAFKEPSRDHNKSSKESSKKPKENKPLKEEKIVPKMAFKEPK 257
KL++E + K + + F E + S K KE++ ++ E+ K +E K
Sbjct: 254 KLIEESQRKMNALFEGRRIEFAEQINKMEARPRRQSMKEKEHQVVRNEE--QKAEQEEGK 311
Query: 258 PMSKEPKPDSNLLTITSGQDKKAPSKRPPISDSEELSAKKRKKSSSEALFKSFSSAPPLI 317
+E + L T Q + EE ++ K+ + I
Sbjct: 312 VAQREEE-----LEETGNQHNDV--------EIEEAGEEEEKEIA--------------I 344
Query: 318 LTCSADKKQIKDKSHVKMGKVKIESET----SEKKKSTLPPFDDIVDPND---------S 364
+ A+K+Q +++ +M +VK+E ET SEK++ + P ++++D + +
Sbjct: 345 VHSDAEKEQEEEEQKQEM-EVKMEEETEVRESEKQQDSQP--EEVMDVLEMVENVKHVIA 401
Query: 365 DVEENISSKSDSEQPSP--ASSSSSSSSSFTPSQTRQQGPLRSIMKDLHSDDNEEESDEV 422
D E +++ +S +PS AS F ++ L +++ + D E+ES+E
Sbjct: 402 DQEVMETNRVESVEPSENEASKELEPEMEFEIEPDKECKSLSPGKENVSALDMEKESEEK 461
Query: 423 EDNDNDSEMERPVNRGGSRSRRVSLSDGSDSESSSASSPLHHEPPP 468
E+ +++ + E PV + +S+ + S S P+ PP
Sbjct: 462 EEKESEPQPE-PVAQPQPQSQ-------PQLQLQSQSQPVLQSQPP 499
>gi|95147342 chromodomain helicase DNA binding protein 9 [Homo
sapiens]
Length = 2881
Score = 70.5 bits (171), Expect = 4e-12
Identities = 43/78 (55%), Positives = 53/78 (67%)
Query: 145 SIHTSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFSKPHKLMKEHK 204
S + SSSSSSSSS S S S SSSSSSSS SS+SSSSSSS+SSSSS+S S + + +
Sbjct: 2142 SCSSRSSSSSSSSSCSHSRSGSSSSSSSSCSSASSSSSSSTSSSSSSSSSSSEESDSDEE 2201
Query: 205 EKPSKDSREHKSAFKEPS 222
E ++S H A+ E S
Sbjct: 2202 EAQKRESTTHMKAYDEES 2219
Score = 59.7 bits (143), Expect = 7e-09
Identities = 46/97 (47%), Positives = 51/97 (52%), Gaps = 10/97 (10%)
Query: 144 RSIHTSSSSSSSSSSSSSSSSSSSSSSSSS-------SSSSSSSSSSSSSSSSSTSFSKP 196
R +SS S S S SS SS SSSSSSSSS SSSSSSSS SS+SSSSS+S S
Sbjct: 2126 RGSESSSDSDSDSERSSCSSRSSSSSSSSSCSHSRSGSSSSSSSSCSSASSSSSSSTSSS 2185
Query: 197 HKLMKEHKEKPSKDSREHKSAFKEPSRDHNKSSKESS 233
E+ D E A K S H K+ E S
Sbjct: 2186 SSSSSSSSEESDSDEEE---AQKRESTTHMKAYDEES 2219
Score = 52.0 bits (123), Expect = 1e-06
Identities = 35/77 (45%), Positives = 45/77 (58%)
Query: 143 NRSIHTSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFSKPHKLMKE 202
+RS +SSSSSS SS+SSSSSSS+SSSSSSSSSSS S S + S + +E
Sbjct: 2159 SRSGSSSSSSSSCSSASSSSSSSTSSSSSSSSSSSEESDSDEEEAQKRESTTHMKAYDEE 2218
Query: 203 HKEKPSKDSREHKSAFK 219
S E + +F+
Sbjct: 2219 SVASLSTTQDETQDSFQ 2235
Score = 48.1 bits (113), Expect = 2e-05
Identities = 36/95 (37%), Positives = 42/95 (44%), Gaps = 3/95 (3%)
Query: 142 PNRSIHTSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS---SSSSSSSTSFSKPHK 198
PN + S SSS S S S SS SS SSSSSSSSS S S SSS+S S
Sbjct: 2114 PNPASKKPRVHKRGSESSSDSDSDSERSSCSSRSSSSSSSSSCSHSRSGSSSSSSSSCSS 2173
Query: 199 LMKEHKEKPSKDSREHKSAFKEPSRDHNKSSKESS 233
S S S+ +E D ++ K S
Sbjct: 2174 ASSSSSSSTSSSSSSSSSSSEESDSDEEEAQKRES 2208
Score = 46.2 bits (108), Expect = 8e-05
Identities = 40/113 (35%), Positives = 48/113 (42%), Gaps = 12/113 (10%)
Query: 133 RKLLKAGGDPNRSIHTSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTS 192
R+++ A +P S S SSS S S S SS SS SSSSSSSSS S S S
Sbjct: 2102 RRMVAARTEPLTPNPASKKPRVHKRGSESSSDSDSDSERSSCSSRSSSSSSSSSCSHSRS 2161
Query: 193 FSKPHKLMKEHKEKPSKDSREHKSAFKEPSRDHNKSSKESSKKPKENKPLKEE 245
S S S SA S + SS SS +E+ +EE
Sbjct: 2162 GSS------------SSSSSSCSSASSSSSSSTSSSSSSSSSSSEESDSDEEE 2202
Score = 45.8 bits (107), Expect = 1e-04
Identities = 31/86 (36%), Positives = 40/86 (46%)
Query: 158 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFSKPHKLMKEHKEKPSKDSREHKSA 217
S SSS S S S SS SS SSSSSSSSS S S + S S S S+
Sbjct: 2128 SESSSDSDSDSERSSCSSRSSSSSSSSSCSHSRSGSSSSSSSSCSSASSSSSSSTSSSSS 2187
Query: 218 FKEPSRDHNKSSKESSKKPKENKPLK 243
S + + S +E ++K + +K
Sbjct: 2188 SSSSSSEESDSDEEEAQKRESTTHMK 2213
Score = 45.8 bits (107), Expect = 1e-04
Identities = 30/79 (37%), Positives = 37/79 (46%)
Query: 157 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFSKPHKLMKEHKEKPSKDSREHKS 216
S SSS S S S SS SS SSSSSSSSS S S S S S S + S
Sbjct: 2128 SESSSDSDSDSERSSCSSRSSSSSSSSSCSHSRSGSSSSSSSSCSSASSSSSSSTSSSSS 2187
Query: 217 AFKEPSRDHNKSSKESSKK 235
+ S + + +E+ K+
Sbjct: 2188 SSSSSSEESDSDEEEAQKR 2206
Score = 45.1 bits (105), Expect = 2e-04
Identities = 27/72 (37%), Positives = 40/72 (55%)
Query: 140 GDPNRSIHTSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFSKPHKL 199
G + S + SS+SSSSSSS+SSSSSSSSSSS S S + S++ ++ +
Sbjct: 2162 GSSSSSSSSCSSASSSSSSSTSSSSSSSSSSSEESDSDEEEAQKRESTTHMKAYDEESVA 2221
Query: 200 MKEHKEKPSKDS 211
+ ++DS
Sbjct: 2222 SLSTTQDETQDS 2233
Score = 40.4 bits (93), Expect = 0.004
Identities = 28/80 (35%), Positives = 34/80 (42%)
Query: 165 SSSSSSSSSSSSSSSSSSSSSSSSSSTSFSKPHKLMKEHKEKPSKDSREHKSAFKEPSRD 224
S SSS S S S SS SS SSSSSSS+S S + S+ S
Sbjct: 2128 SESSSDSDSDSERSSCSSRSSSSSSSSSCSHSRSGSSSSSSSSCSSASSSSSSSTSSSSS 2187
Query: 225 HNKSSKESSKKPKENKPLKE 244
+ SS E S +E +E
Sbjct: 2188 SSSSSSEESDSDEEEAQKRE 2207
Score = 39.7 bits (91), Expect = 0.007
Identities = 31/101 (30%), Positives = 37/101 (36%)
Query: 166 SSSSSSSSSSSSSSSSSSSSSSSSSTSFSKPHKLMKEHKEKPSKDSREHKSAFKEPSRDH 225
S SSS S S S SS SS SSSSSS+S + S S S+ S
Sbjct: 2128 SESSSDSDSDSERSSCSSRSSSSSSSSSCSHSRSGSSSSSSSSCSSASSSSSSSTSSSSS 2187
Query: 226 NKSSKESSKKPKENKPLKEEKIVPKMAFKEPKPMSKEPKPD 266
+ SS E + K E A+ E S D
Sbjct: 2188 SSSSSSEESDSDEEEAQKRESTTHMKAYDEESVASLSTTQD 2228
Score = 38.1 bits (87), Expect = 0.022
Identities = 24/71 (33%), Positives = 37/71 (52%)
Query: 148 TSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFSKPHKLMKEHKEKP 207
+SSSSSS+SSSSSSSSSSS S S + S++ + S + E ++
Sbjct: 2175 SSSSSSSTSSSSSSSSSSSEESDSDEEEAQKRESTTHMKAYDEESVASLSTTQDETQDSF 2234
Query: 208 SKDSREHKSAF 218
++ +SA+
Sbjct: 2235 QMNNGTPESAY 2245
Score = 36.2 bits (82), Expect = 0.083
Identities = 33/146 (22%), Positives = 54/146 (36%), Gaps = 5/146 (3%)
Query: 137 KAGGDPNRSIHTSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFSKP 196
K+GG ++ + + + +S S SSS S S S SS SS +S S
Sbjct: 2093 KSGGKCETDRRMVAARTEPLTPNPASKKPRVHKRGSESSSDSDSDSERSSCSSRSSSSSS 2152
Query: 197 HKLMKEHKEKPSKDSREHKSAFKEPSRDHNKSSKESSKKPKENKPLKEEKIVPKMAFKEP 256
+ S S S+ S SS SS E EE+ + +
Sbjct: 2153 SSSCSHSRSGSSSSSSSSCSSASSSSSSSTSSSSSSSSSSSEESDSDEEEAQKRESTTHM 2212
Query: 257 KPMSKEPKPDSNLLTITSGQDKKAPS 282
K +E ++ ++++ QD+ S
Sbjct: 2213 KAYDEE-----SVASLSTTQDETQDS 2233
Score = 35.4 bits (80), Expect = 0.14
Identities = 52/228 (22%), Positives = 85/228 (37%), Gaps = 17/228 (7%)
Query: 212 REHKSAFKEPSRDHNKSSKESSKKPKENKPLKEEKIVPKMAFKEPKPMSKEPKP-DSNLL 270
R+ + +F R++++S S+ + PL ++ V A P++ P+ D+ +
Sbjct: 1988 RDPELSFMAAQRNYSQSKMAHSRT---STPLLQQYQVALSA----SPLTSLPRLLDAKGI 2040
Query: 271 TITSGQDKKAPSKRPPISDSEEL--SAKKRKKSSSEALFKSFSSAPPLILTCSADKKQIK 328
+ + K K P S EE S + R SE + P + K
Sbjct: 2041 ILEEMKVKSENLKEEPQSSEEESMSSVETRTLIKSEPVSPKNGVLPQATGDQKSGGKCET 2100
Query: 329 DKSHVKMGKVKIESETSEKKKSTLPPFDDIVDPNDSDVEENISSKSDSEQPSPAS----- 383
D+ V + + KK + +DSD E + S S S +S
Sbjct: 2101 DRRMVAARTEPLTPNPASKKPRVHKRGSESSSDSDSDSERSSCSSRSSSSSSSSSCSHSR 2160
Query: 384 --SSSSSSSSFTPSQTRQQGPLRSIMKDLHSDDNEEESDEVEDNDNDS 429
SSSSSSSS + + + S S E +SDE E +S
Sbjct: 2161 SGSSSSSSSSCSSASSSSSSSTSSSSSSSSSSSEESDSDEEEAQKRES 2208
Score = 35.0 bits (79), Expect = 0.18
Identities = 31/138 (22%), Positives = 53/138 (38%), Gaps = 20/138 (14%)
Query: 367 EENISSKSDSEQPSPASSSSSSSSSFTPSQTRQQGPLRSIMKDLHSDDNEEESDEVEDND 426
E + S SDSE+ S +S SSSSSSS + S +R S + + S +
Sbjct: 2129 ESSSDSDSDSERSSCSSRSSSSSSSSSCSHSRSGSSSSSSSSCSSASSSSSSSTSSSSSS 2188
Query: 427 NDSEMERPVNRGGSRSRRVSLSDGSDSESSSASSPLHHEPPPPLLKTNNNQILEVKSPIK 486
+ S E SD + E+ S H + + + + +
Sbjct: 2189 SSSSSEE--------------SDSDEEEAQKRESTTH------MKAYDEESVASLSTTQD 2228
Query: 487 QSKSDKQIKNGECDKAYL 504
+++ Q+ NG + AY+
Sbjct: 2229 ETQDSFQMNNGTPESAYI 2246
Score = 32.3 bits (72), Expect = 1.2
Identities = 32/160 (20%), Positives = 72/160 (45%), Gaps = 8/160 (5%)
Query: 137 KAGGDPNRSIHTSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFSK- 195
K G D S + + S SS + +S SSS S+SS+++ +++++++ + + S
Sbjct: 2726 KKGSDSKESEGKTERTESQSSENGGENSVSSSPSTSSTAALNTAAAANPLALNPLLLSNI 2785
Query: 196 --PHKLMKEHKEKPSKDSREHKSAFKEPSRDHNKSSKESSKKPKENKPLKEEKIVPKMAF 253
P L+ + + F +++ + S +S + +E+ +K+++
Sbjct: 2786 LYPGMLLTPGLNL-HIPTLSQSNTFDVQNKNSDLGSSKSVEVKEEDSRIKDQE---DKGG 2841
Query: 254 KEPKPMSKEPKPD-SNLLTITSGQDKKAPSKRPPISDSEE 292
EP P+++ + S +SG D + S S +E+
Sbjct: 2842 TEPSPLNENSTDEGSEKADASSGSDSTSSSSEDSDSSNED 2881
Score = 31.6 bits (70), Expect = 2.0
Identities = 52/267 (19%), Positives = 94/267 (35%), Gaps = 25/267 (9%)
Query: 141 DPNRSIHTSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFSKPHKLM 200
DP S + + S S + S +S+ + S+S +S + + K+
Sbjct: 1989 DPELSFMAAQRNYSQSKMAHSRTSTPLLQQYQVALSASPLTSLPRLLDAKGIILEEMKVK 2048
Query: 201 KEH-KEKPSKDSREHKSAFK-------EPSRDHNKSSKESSKKPKENKPLKEEK--IVPK 250
E+ KE+P E S+ + EP N +++ K + ++ + +
Sbjct: 2049 SENLKEEPQSSEEESMSSVETRTLIKSEPVSPKNGVLPQATGDQKSGGKCETDRRMVAAR 2108
Query: 251 MAFKEPKPMSKEPKPDSNLLTITSGQDKKAPSKRPPISDSEELSAKKRKKSSSEALFKSF 310
P P SK+P+ +S D SDSE S R SSS + S
Sbjct: 2109 TEPLTPNPASKKPRVHKRGSESSSDSD----------SDSERSSCSSRSSSSSSSSSCSH 2158
Query: 311 S---SAPPLILTCSADKKQIKDKSHVKMGKVKIESETSEKKKSTLPPFDDIVDPNDSDVE 367
S S+ +CS+ + SE S+ + + D E
Sbjct: 2159 SRSGSSSSSSSSCSSASSSSSSSTSSSSSSSSSSSEESDSDEEEAQKRESTTHMKAYDEE 2218
Query: 368 E--NISSKSDSEQPSPASSSSSSSSSF 392
++S+ D Q S ++ + S++
Sbjct: 2219 SVASLSTTQDETQDSFQMNNGTPESAY 2245
Score = 31.6 bits (70), Expect = 2.0
Identities = 42/204 (20%), Positives = 78/204 (38%), Gaps = 9/204 (4%)
Query: 309 SFSSAPPLILTCSADKKQI-KDKSHVKMGKVKIESETSEKKKSTLPPFDDIVDPNDSDVE 367
+ S++P L D K I ++ VK +K E ++SE++ + ++ +
Sbjct: 2022 ALSASPLTSLPRLLDAKGIILEEMKVKSENLKEEPQSSEEESMSSVETRTLIKSEPVSPK 2081
Query: 368 ENISSKSDSEQPSPASSSSSSSSSFTPSQTRQQGPLRSIMKDLHSDDNEEESDEVEDNDN 427
+ ++ +Q S + ++ P S +H +E SD +D+
Sbjct: 2082 NGVLPQATGDQKSGGKCETDRRMVAARTEPLTPNPA-SKKPRVHKRGSESSSD----SDS 2136
Query: 428 DSEMERPVNRGGSRSRRVSLSDGSDSESSSASSPLHHEPPPPLLKTNNNQILEVKSPIKQ 487
DSE +R S S S S SSS+SS T+++ S +
Sbjct: 2137 DSERSSCSSRSSSSSSSSSCSHSRSGSSSSSSSSCSSASSSSSSSTSSSSSSSSSSSEES 2196
Query: 488 SKSDKQIKNGECD---KAYLDELV 508
+++ + E KAY +E V
Sbjct: 2197 DSDEEEAQKRESTTHMKAYDEESV 2220
Score = 30.0 bits (66), Expect = 5.9
Identities = 38/153 (24%), Positives = 62/153 (40%), Gaps = 35/153 (22%)
Query: 341 ESETSEKKKSTLPPFDDIVDPNDSDVEENISSKSDSEQPSPASSSS-SSSSSFTP----- 394
ES T +KK S + + +S EN S S PS +S+++ +++++ P
Sbjct: 2720 ESGTEDKKGSDSKESEGKTERTESQSSENGGENSVSSSPSTSSTAALNTAAAANPLALNP 2779
Query: 395 ---SQTRQQGPLRSIMKDLH---------SDDNEEESD-----EVEDNDNDSEMERPVNR 437
S G L + +LH D + SD VE + DS ++ ++
Sbjct: 2780 LLLSNILYPGMLLTPGLNLHIPTLSQSNTFDVQNKNSDLGSSKSVEVKEEDSRIKDQEDK 2839
Query: 438 GGSR------------SRRVSLSDGSDSESSSA 458
GG+ S + S GSDS SSS+
Sbjct: 2840 GGTEPSPLNENSTDEGSEKADASSGSDSTSSSS 2872
>gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]
Length = 494
Score = 70.1 bits (170), Expect = 5e-12
Identities = 83/327 (25%), Positives = 130/327 (39%), Gaps = 40/327 (12%)
Query: 137 KAGGDPNRSIHTSSSSSSSSSSSSSSSSSSS-SSSSSSSSSSSSSSSSSSSSSSSTSFSK 195
K G RS S S S S S S S S S S SS SS S S S S S S S S S S+
Sbjct: 176 KPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSR 235
Query: 196 PHKLMKEHKEKPSKDSREHKSAFKEPSRDHNKSSKESSKKPKENKPLKEEKIVPKMAFKE 255
+ KEK S+E K SR H+ S K + + ++ V K +
Sbjct: 236 SQSRSRSKKEKSRSPSKE-----KSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRS 290
Query: 256 PKPMSKEPKPDSNLLTITSGQDKKAPSKRPPISDSEELSAKKRKKSSSEALFKSFSSAPP 315
P + K S ++K+ R + ++ R +S + +S S +
Sbjct: 291 PSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSK- 349
Query: 316 LILTCSADKKQIKDKSHVKMGKVKIESETSEKKKSTLPPFDDIVDPNDSDVEENISSKSD 375
S DK++ + +S + ES + + +S + S K
Sbjct: 350 -----SKDKRKGRKRS-------REESRSRSRSRS----------------KSERSRKRG 381
Query: 376 SEQPSPASSSSSSSSSFTPSQTRQQGPLRSIMKD---LHSDDNEEESDEVEDNDNDSEME 432
S++ S A SS T +++ + P RS+ K+ S+ ++ E +N ++
Sbjct: 382 SKRDSKAGSSKKKKKEDT-DRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQET 440
Query: 433 RPVNRGGSRSRRVSLSDGSDSESSSAS 459
R +R S+S + +L S S S SAS
Sbjct: 441 RSRSRSNSKS-KPNLPSESRSRSKSAS 466
Score = 62.4 bits (150), Expect = 1e-09
Identities = 74/281 (26%), Positives = 103/281 (36%), Gaps = 18/281 (6%)
Query: 143 NRSIHTSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS----STSFSKPHK 198
+RS H+ S S S SS SS S S S S S S S S S S S S S S S S SK
Sbjct: 196 SRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKS 255
Query: 199 LMKEHK----EKPSKDSREHK---------SAFKEPSRDHNKSSKESSKKPKENKPLKEE 245
+ H SKD E K + PSR +KS S + + + K
Sbjct: 256 RSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRG 315
Query: 246 KIVPKMAFKEPKPMSKEPKPDSNLLTITSGQDKKAPSKRPPISDS-EELSAKKRKKSSSE 304
+ + ++ S+ S K+ KR S EE ++ R +S SE
Sbjct: 316 SVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSE 375
Query: 305 ALFKSFSSAPPLILTCSADKKQIKDKSHVKMGKVKIESETSEKKKSTLPPFDDIVDPNDS 364
K S + KK+ D+S + + E K + N
Sbjct: 376 RSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAG 435
Query: 365 DVEENISSKSDSEQPSPASSSSSSSSSFTPSQTRQQGPLRS 405
+E S + + P S S S S + S+TR + RS
Sbjct: 436 TNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRS 476
Score = 58.2 bits (139), Expect = 2e-08
Identities = 77/300 (25%), Positives = 114/300 (38%), Gaps = 51/300 (17%)
Query: 133 RKLLKAGGDPNRSIHTSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTS 192
RK G S S S S S S S S S S S S S S S S S S S S S
Sbjct: 202 RKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHS 261
Query: 193 FSKPHKLMKEHKE----------KP-SKDSREHKSAFKEPSRDHNKSSKES-----SKKP 236
K K+ E KP S+ HKS K SR + +E S+
Sbjct: 262 AGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGR 321
Query: 237 KENKPLKEEKIVPKMAF---------------KEPKPMSKEPKPDSNLLTITSGQDKKAP 281
+ K L++ + + ++ + S+E + S + +K
Sbjct: 322 SQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRG 381
Query: 282 SKRPPISDSEELSAKKRKKSSSEALFKSFSSAPPLILTCSADKKQIKDKSHVKMGKVKIE 341
SKR DS+ S+KK+KK ++ +S S +P + S +++ K +S + G+ + E
Sbjct: 382 SKR----DSKAGSSKKKKKEDTD---RSQSRSPSR--SVSKEREHAKSESSQREGRGESE 432
Query: 342 -----------SETSEKKKSTLPPFDDIVDPNDSDVEENISSKSDSEQPSPASSSSSSSS 390
S ++ K K LP + S S+S S SP+ S S S S
Sbjct: 433 NAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSASRSPSRSRSRSHS 492
>gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens]
Length = 953
Score = 70.1 bits (170), Expect = 5e-12
Identities = 76/276 (27%), Positives = 104/276 (37%), Gaps = 20/276 (7%)
Query: 132 RRKLLKAGGDPNRSIHTSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSST 191
RRK + + S +SS SSS S S SS S S SSS SS SS SS SS S S S S
Sbjct: 541 RRKTSASSASASNSSRSSSRSSSYSGSGSSRSRSRSSSYSSYSSRSSRHSSFSGSRSRSR 600
Query: 192 SFSKPHKLMKEHKEKPSKDSREHKSAFK---EPSRDHNKSSKESSKKPKENKPLKEEKIV 248
SFS PS H+ + + EP+ K+ ++S KKP
Sbjct: 601 SFSS--------SPSPSPTPSPHRPSIRTKGEPAPPPGKAGEKSVKKPAPPP-------A 645
Query: 249 PKMAFKEPKPMSKEPKPDSNLLTITSGQDKKAPSKRPPISDSEELSAKKRKKSSSEALFK 308
P A K P+ + KP + + P +R +S S S SSS +
Sbjct: 646 PPQATKTTAPVPEPTKPGDPREARRKERPARTPPRRRTLSGSGSGSGSSYSGSSSRSRSL 705
Query: 309 SFSSAPPL-ILTCSADKKQIKDKSHVKMGKVKIESETSEKKKSTLPPFDDIVDPNDSD-V 366
S SS + T S+ D + S S + + + D V
Sbjct: 706 SVSSVSSVSSATSSSSSAHSVDSEDMYADLASPVSSASSRSPAPAQTRKEKGKSKKEDGV 765
Query: 367 EENISSKSDSEQPSPASSSSSSSSSFTPSQTRQQGP 402
+E + S QP ++ + S T QQ P
Sbjct: 766 KEEKRKRDSSTQPPKSAKPPAGGKSSQQPSTPQQAP 801
Score = 58.9 bits (141), Expect = 1e-08
Identities = 67/268 (25%), Positives = 107/268 (39%), Gaps = 28/268 (10%)
Query: 132 RRKLLKAGGDPNRSIHTSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS----SSSSSSSS 187
RR L +G S SSS S S S SS SS SS++SSSSS+ S S + +S S
Sbjct: 681 RRTLSGSGSGSGSSYSGSSSRSRSLSVSSVSSVSSATSSSSSAHSVDSEDMYADLASPVS 740
Query: 188 SSSTSFSKPHKLMKEHKEKPSKDSREHKSAFKEPSRDHNKSSKESSKKPKENKPLKEEKI 247
S+S+ P + KE + +D + + ++ S KS+K + +P ++
Sbjct: 741 SASSRSPAPAQTRKEKGKSKKEDGVKEEKRKRDSSTQPPKSAKPPAGGKSSQQPSTPQQA 800
Query: 248 VPKMAFKEPKPMSKEPKPDSNLLTITSGQDKKAPSKRPPISDSEELSAKKRKKSSSEALF 307
P + KE K LT+ + K KR SD + S K+ ++
Sbjct: 801 PPGQPQQGTFVAHKEIK-----LTLLNKAADKGSRKRYEPSDKDRQSPPPAKRPNT---- 851
Query: 308 KSFSSAPPLILTCSADKKQIKDKSHVKMGKVKIESETSEKKKSTLPPFD--DIVDPNDSD 365
S D+ KS ++G K E + + K+ P D + P
Sbjct: 852 -------------SPDRGSRDRKSGGRLGSPKPERQRGQNSKAPAAPADRKRQLSPQSKS 898
Query: 366 VEENISSKSDSEQPSPASSSSSSSSSFT 393
+ S + P AS+ S +S+ +
Sbjct: 899 SSKVTSVPGKASDPGAASTKSGKASTLS 926
Score = 38.9 bits (89), Expect = 0.013
Identities = 58/327 (17%), Positives = 119/327 (36%), Gaps = 51/327 (15%)
Query: 195 KPHKLMKEHKEKPSKDSREHKSAFKEPSRDHNKSSKESSKKPKENKPLKEEKIVPKMAFK 254
+ H+ KE + + + RE ++ E R H +E ++ ++ KP +
Sbjct: 438 REHERDKERQRRKEEWERE-RAKRDEKDRQHRDRDREKEREKEKGKPKP----------R 486
Query: 255 EPKPMSKEPKPDSNLLTITSGQDK------------KAPSKRPPISDSEELSAKKRKKSS 302
P+P S++ +P T Q K K+P K+ +S S + ++RK S+
Sbjct: 487 SPQPPSRQAEPPKKEAATTGPQVKRADEWKDPWRRSKSPKKKLGVSVSPSRARRRRKTSA 546
Query: 303 SEALFKSFSSAPPLILTCS---ADKKQIKDKSHVKMGKVKIESETSEKKKSTLPPFDDIV 359
S A + S + + S + + + + S+ + +S F
Sbjct: 547 SSASASNSSRSSSRSSSYSGSGSSRSRSRSSSYSSYSSRSSRHSSFSGSRSRSRSFSSSP 606
Query: 360 DPNDSDVEENISSKSDSE----------------QPSPASSSSSSSSSFTPSQTRQQGPL 403
P+ + S ++ E P PA ++ +++ P T+ P
Sbjct: 607 SPSPTPSPHRPSIRTKGEPAPPPGKAGEKSVKKPAPPPAPPQATKTTAPVPEPTKPGDPR 666
Query: 404 RSIMKDLHSDDNEEESDEVEDNDNDSEMERPVNRGGSRSRRVSLSDGSDSESSSASSPLH 463
+ K+ + + + S + SRSR +S+S S S+++SS
Sbjct: 667 EARRKERPARTPPRRRTL---SGSGSGSGSSYSGSSSRSRSLSVSSVSSVSSATSSSSSA 723
Query: 464 HEPPPPLLKTNNNQILEVKSPIKQSKS 490
H + + ++ SP+ + S
Sbjct: 724 HS------VDSEDMYADLASPVSSASS 744
Score = 38.1 bits (87), Expect = 0.022
Identities = 56/288 (19%), Positives = 111/288 (38%), Gaps = 47/288 (16%)
Query: 201 KEHKEKPSKDSREHKSAFKEPSRDHNKSSKESSKK---PKENKPLKEEKIVPKMAFKEPK 257
++ K++ +D K KE + +S + S++ PK+ ++ +K+P
Sbjct: 460 RDEKDRQHRDRDREKEREKEKGKPKPRSPQPPSRQAEPPKKEAATTGPQVKRADEWKDPW 519
Query: 258 PMSKEPKPDSNLLTITSGQDKKAPSKRPPISDSEEL-------------SAKKRKKSSSE 304
SK PK + S ++ + S S S++ R +SSS
Sbjct: 520 RRSKSPKKKLGVSVSPSRARRRRKTSASSASASNSSRSSSRSSSYSGSGSSRSRSRSSSY 579
Query: 305 ALF-----------------KSFSSAPPLILTCSADKKQIKDKSHV-----KMGKVKIES 342
+ + +SFSS+P T S + I+ K K G+ ++
Sbjct: 580 SSYSSRSSRHSSFSGSRSRSRSFSSSPSPSPTPSPHRPSIRTKGEPAPPPGKAGEKSVKK 639
Query: 343 ET-------SEKKKSTLPPFDDIVDPNDSDVEENISSKSDSEQPSPASSSSSSSSSFTPS 395
+ K + +P DP ++ +E +++ + + + S S S SS++ S
Sbjct: 640 PAPPPAPPQATKTTAPVPEPTKPGDPREARRKER-PARTPPRRRTLSGSGSGSGSSYSGS 698
Query: 396 QTRQQGPLRSIMKDLHSDDNEEES-DEVEDNDNDSEMERPVNRGGSRS 442
+R + S + + S + S V+ D +++ PV+ SRS
Sbjct: 699 SSRSRSLSVSSVSSVSSATSSSSSAHSVDSEDMYADLASPVSSASSRS 746
Score = 30.4 bits (67), Expect = 4.5
Identities = 29/162 (17%), Positives = 54/162 (33%), Gaps = 19/162 (11%)
Query: 364 SDVEENISSKSDSEQPSPASSSSSSSSSFTPSQTRQQGPLRSIMKDLHSDDNEEESD--- 420
SD+E+ S+ Q + S + P Q + + + S EEE D
Sbjct: 46 SDLEDEESAARGPSQEEEDNHSDEEDRASEPKSQDQDSEVNELSRGPTSSPCEEEGDEGE 105
Query: 421 ----------------EVEDNDNDSEMERPVNRGGSRSRRVSLSDGSDSESSSASSPLHH 464
E+++++ D + E P + + G++ +
Sbjct: 106 EDRTSDLRDEASSVTRELDEHELDYDEEVPEEPAPAVQEDEAEKAGAEDDEEKGEGTPRE 165
Query: 465 EPPPPLLKTNNNQILEVKSPIKQSKSDKQIKNGECDKAYLDE 506
E + + LE K+ D +I +GE D L+E
Sbjct: 166 EGKAGVQSVGEKESLEAAKEKKKEDDDGEIDDGEIDDDDLEE 207
>gi|113415504 PREDICTED: similar to ribonucleic acid binding protein
S1 [Homo sapiens]
Length = 305
Score = 69.3 bits (168), Expect = 9e-12
Identities = 46/106 (43%), Positives = 58/106 (54%), Gaps = 5/106 (4%)
Query: 139 GGDPNRSIHTSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFSKPHK 198
G D R H++SS SSS+ S SSS+SSS SS+S+ SSS SSSSS+SS S SS++
Sbjct: 58 GRDKTRKRHSASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSS 117
Query: 199 LMKEHKEKPSK----DSREHKSAFKEPSRDHNKSSKESSKKPKENK 240
PS+ + R +S K P RD K K S PK K
Sbjct: 118 SSSSGSPSPSRRRHDNRRRSRSKSKPPKRD-EKERKRRSPSPKPTK 162
Score = 57.0 bits (136), Expect = 5e-08
Identities = 40/101 (39%), Positives = 54/101 (53%), Gaps = 7/101 (6%)
Query: 132 RRKLLKAGGDPNRSIHTSSSSS-------SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 184
+R +G RS +S+SSS SSS SSSSS+SS S SSS+S SSSSSSSS S
Sbjct: 64 KRHSASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGS 123
Query: 185 SSSSSSTSFSKPHKLMKEHKEKPSKDSREHKSAFKEPSRDH 225
S S ++ K K + R+ +S +P++ H
Sbjct: 124 PSPSRRRHDNRRRSRSKSKPPKRDEKERKRRSPSPKPTKVH 164
Score = 52.8 bits (125), Expect = 9e-07
Identities = 42/129 (32%), Positives = 52/129 (40%), Gaps = 12/129 (9%)
Query: 137 KAGGDPNRSIHTSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFSKP 196
K G S + S+SS SSS+ S SSS+SSS SS+S+ SSS S+S S
Sbjct: 44 KDKGATKESSEKDRGRDKTRKRHSASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSAS 103
Query: 197 HKLMKEHKEKPSKDSREHKSAFKEPSRDHNKSSKESSKKPKENKPLKEEKIVPKMAFKEP 256
+ + S S S R N+ S KP PK KE
Sbjct: 104 SRSGSSSTSRSSSSSSSSGSPSPSRRRHDNRRRSRSKSKP------------PKRDEKER 151
Query: 257 KPMSKEPKP 265
K S PKP
Sbjct: 152 KRRSPSPKP 160
Score = 40.8 bits (94), Expect = 0.003
Identities = 28/78 (35%), Positives = 36/78 (46%)
Query: 148 TSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFSKPHKLMKEHKEKP 207
+SS+SS S SSS+S SSSSSSSS S S S + S S S + K K P
Sbjct: 99 SSSASSRSGSSSTSRSSSSSSSSGSPSPSRRRHDNRRRSRSKSKPPKRDEKERKRRSPSP 158
Query: 208 SKDSREHKSAFKEPSRDH 225
+ ++DH
Sbjct: 159 KPTKVHIGRLTRNVTKDH 176
Score = 40.0 bits (92), Expect = 0.006
Identities = 38/140 (27%), Positives = 58/140 (41%), Gaps = 17/140 (12%)
Query: 280 APSKRPPISDSEELSAKKRKKSSSEALFKSFSSAPPLILTCSADKKQIKDKSHVKMGKVK 339
+P+KR SD + K K ++ E S++K + +DK+ +
Sbjct: 27 SPTKRKDRSDEKSKDRSKDKGATKE----------------SSEKDRGRDKTRKRHSASS 70
Query: 340 IESETSEKKKSTLPPFDDIVDPNDS-DVEENISSKSDSEQPSPASSSSSSSSSFTPSQTR 398
S T + ST + S + SS+S S S +SSSSSSS S +PS+ R
Sbjct: 71 GSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSPSPSRRR 130
Query: 399 QQGPLRSIMKDLHSDDNEEE 418
RS K +E+E
Sbjct: 131 HDNRRRSRSKSKPPKRDEKE 150
Score = 29.6 bits (65), Expect = 7.8
Identities = 39/159 (24%), Positives = 53/159 (33%), Gaps = 5/159 (3%)
Query: 292 ELSAKKRKK--SSSEALFKSFSSAPPLILTCSADKKQIKDKSHVKMGKVKIESETSEKKK 349
+LS K+K E KS + AP ++ KD+S K G K SE +
Sbjct: 2 DLSGVKKKSLLGVKENNKKSSTRAPSPTKRKDRSDEKSKDRSKDK-GATKESSEKDRGRD 60
Query: 350 STLPPFDDIVDPNDSDVEENISSKSDSEQPSPASSSSSSSSSFTPSQTRQQGPLRSIMKD 409
T S SS S S + SSS SSSS S++ RS
Sbjct: 61 KTRKRHS--ASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSS 118
Query: 410 LHSDDNEEESDEVEDNDNDSEMERPVNRGGSRSRRVSLS 448
S ++ +P R +R S S
Sbjct: 119 SSSGSPSPSRRRHDNRRRSRSKSKPPKRDEKERKRRSPS 157
>gi|169166499 PREDICTED: similar to ribonucleic acid binding protein
S1 [Homo sapiens]
Length = 305
Score = 69.3 bits (168), Expect = 9e-12
Identities = 46/106 (43%), Positives = 58/106 (54%), Gaps = 5/106 (4%)
Query: 139 GGDPNRSIHTSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFSKPHK 198
G D R H++SS SSS+ S SSS+SSS SS+S+ SSS SSSSS+SS S SS++
Sbjct: 58 GRDKTRKRHSASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSS 117
Query: 199 LMKEHKEKPSK----DSREHKSAFKEPSRDHNKSSKESSKKPKENK 240
PS+ + R +S K P RD K K S PK K
Sbjct: 118 SSSSGSPSPSRRRHDNRRRSRSKSKPPKRD-EKERKRRSPSPKPTK 162
Score = 57.0 bits (136), Expect = 5e-08
Identities = 40/101 (39%), Positives = 54/101 (53%), Gaps = 7/101 (6%)
Query: 132 RRKLLKAGGDPNRSIHTSSSSS-------SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 184
+R +G RS +S+SSS SSS SSSSS+SS S SSS+S SSSSSSSS S
Sbjct: 64 KRHSASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGS 123
Query: 185 SSSSSSTSFSKPHKLMKEHKEKPSKDSREHKSAFKEPSRDH 225
S S ++ K K + R+ +S +P++ H
Sbjct: 124 PSPSRRRHDNRRRSRSKSKPPKRDEKERKRRSPSPKPTKVH 164
Score = 52.8 bits (125), Expect = 9e-07
Identities = 42/129 (32%), Positives = 52/129 (40%), Gaps = 12/129 (9%)
Query: 137 KAGGDPNRSIHTSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFSKP 196
K G S + S+SS SSS+ S SSS+SSS SS+S+ SSS S+S S
Sbjct: 44 KDKGATKESSEKDRGRDKTRKRHSASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSAS 103
Query: 197 HKLMKEHKEKPSKDSREHKSAFKEPSRDHNKSSKESSKKPKENKPLKEEKIVPKMAFKEP 256
+ + S S S R N+ S KP PK KE
Sbjct: 104 SRSGSSSTSRSSSSSSSSGSPSPSRRRHDNRRRSRSKSKP------------PKRDEKER 151
Query: 257 KPMSKEPKP 265
K S PKP
Sbjct: 152 KRRSPSPKP 160
Score = 40.8 bits (94), Expect = 0.003
Identities = 28/78 (35%), Positives = 36/78 (46%)
Query: 148 TSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFSKPHKLMKEHKEKP 207
+SS+SS S SSS+S SSSSSSSS S S S + S S S + K K P
Sbjct: 99 SSSASSRSGSSSTSRSSSSSSSSGSPSPSRRRHDNRRRSRSKSKPPKRDEKERKRRSPSP 158
Query: 208 SKDSREHKSAFKEPSRDH 225
+ ++DH
Sbjct: 159 KPTKVHIGRLTRNVTKDH 176
Score = 40.0 bits (92), Expect = 0.006
Identities = 38/140 (27%), Positives = 58/140 (41%), Gaps = 17/140 (12%)
Query: 280 APSKRPPISDSEELSAKKRKKSSSEALFKSFSSAPPLILTCSADKKQIKDKSHVKMGKVK 339
+P+KR SD + K K ++ E S++K + +DK+ +
Sbjct: 27 SPTKRKDRSDEKSKDRSKDKGATKE----------------SSEKDRGRDKTRKRHSASS 70
Query: 340 IESETSEKKKSTLPPFDDIVDPNDS-DVEENISSKSDSEQPSPASSSSSSSSSFTPSQTR 398
S T + ST + S + SS+S S S +SSSSSSS S +PS+ R
Sbjct: 71 GSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSPSPSRRR 130
Query: 399 QQGPLRSIMKDLHSDDNEEE 418
RS K +E+E
Sbjct: 131 HDNRRRSRSKSKPPKRDEKE 150
Score = 29.6 bits (65), Expect = 7.8
Identities = 39/159 (24%), Positives = 53/159 (33%), Gaps = 5/159 (3%)
Query: 292 ELSAKKRKK--SSSEALFKSFSSAPPLILTCSADKKQIKDKSHVKMGKVKIESETSEKKK 349
+LS K+K E KS + AP ++ KD+S K G K SE +
Sbjct: 2 DLSGVKKKSLLGVKENNKKSSTRAPSPTKRKDRSDEKSKDRSKDK-GATKESSEKDRGRD 60
Query: 350 STLPPFDDIVDPNDSDVEENISSKSDSEQPSPASSSSSSSSSFTPSQTRQQGPLRSIMKD 409
T S SS S S + SSS SSSS S++ RS
Sbjct: 61 KTRKRHS--ASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSS 118
Query: 410 LHSDDNEEESDEVEDNDNDSEMERPVNRGGSRSRRVSLS 448
S ++ +P R +R S S
Sbjct: 119 SSSGSPSPSRRRHDNRRRSRSKSKPPKRDEKERKRRSPS 157
>gi|113415498 PREDICTED: similar to ribonucleic acid binding protein
S1 [Homo sapiens]
Length = 305
Score = 69.3 bits (168), Expect = 9e-12
Identities = 46/106 (43%), Positives = 58/106 (54%), Gaps = 5/106 (4%)
Query: 139 GGDPNRSIHTSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFSKPHK 198
G D R H++SS SSS+ S SSS+SSS SS+S+ SSS SSSSS+SS S SS++
Sbjct: 58 GRDKTRKRHSASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSS 117
Query: 199 LMKEHKEKPSK----DSREHKSAFKEPSRDHNKSSKESSKKPKENK 240
PS+ + R +S K P RD K K S PK K
Sbjct: 118 SSSSGSPSPSRRRHDNRRRSRSKSKPPKRD-EKERKRRSPSPKPTK 162
Score = 57.0 bits (136), Expect = 5e-08
Identities = 40/101 (39%), Positives = 54/101 (53%), Gaps = 7/101 (6%)
Query: 132 RRKLLKAGGDPNRSIHTSSSSS-------SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 184
+R +G RS +S+SSS SSS SSSSS+SS S SSS+S SSSSSSSS S
Sbjct: 64 KRHSASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGS 123
Query: 185 SSSSSSTSFSKPHKLMKEHKEKPSKDSREHKSAFKEPSRDH 225
S S ++ K K + R+ +S +P++ H
Sbjct: 124 PSPSRRRHDNRRRSRSKSKPPKRDEKERKRRSPSPKPTKVH 164
Score = 52.8 bits (125), Expect = 9e-07
Identities = 42/129 (32%), Positives = 52/129 (40%), Gaps = 12/129 (9%)
Query: 137 KAGGDPNRSIHTSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFSKP 196
K G S + S+SS SSS+ S SSS+SSS SS+S+ SSS S+S S
Sbjct: 44 KDKGATKESSEKDRGRDKTRKRHSASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSAS 103
Query: 197 HKLMKEHKEKPSKDSREHKSAFKEPSRDHNKSSKESSKKPKENKPLKEEKIVPKMAFKEP 256
+ + S S S R N+ S KP PK KE
Sbjct: 104 SRSGSSSTSRSSSSSSSSGSPSPSRRRHDNRRRSRSKSKP------------PKRDEKER 151
Query: 257 KPMSKEPKP 265
K S PKP
Sbjct: 152 KRRSPSPKP 160
Score = 40.8 bits (94), Expect = 0.003
Identities = 28/78 (35%), Positives = 36/78 (46%)
Query: 148 TSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFSKPHKLMKEHKEKP 207
+SS+SS S SSS+S SSSSSSSS S S S + S S S + K K P
Sbjct: 99 SSSASSRSGSSSTSRSSSSSSSSGSPSPSRRRHDNRRRSRSKSKPPKRDEKERKRRSPSP 158
Query: 208 SKDSREHKSAFKEPSRDH 225
+ ++DH
Sbjct: 159 KPTKVHIGRLTRNVTKDH 176
Score = 40.0 bits (92), Expect = 0.006
Identities = 38/140 (27%), Positives = 58/140 (41%), Gaps = 17/140 (12%)
Query: 280 APSKRPPISDSEELSAKKRKKSSSEALFKSFSSAPPLILTCSADKKQIKDKSHVKMGKVK 339
+P+KR SD + K K ++ E S++K + +DK+ +
Sbjct: 27 SPTKRKDRSDEKSKDRSKDKGATKE----------------SSEKDRGRDKTRKRHSASS 70
Query: 340 IESETSEKKKSTLPPFDDIVDPNDS-DVEENISSKSDSEQPSPASSSSSSSSSFTPSQTR 398
S T + ST + S + SS+S S S +SSSSSSS S +PS+ R
Sbjct: 71 GSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSPSPSRRR 130
Query: 399 QQGPLRSIMKDLHSDDNEEE 418
RS K +E+E
Sbjct: 131 HDNRRRSRSKSKPPKRDEKE 150
Score = 29.6 bits (65), Expect = 7.8
Identities = 39/159 (24%), Positives = 53/159 (33%), Gaps = 5/159 (3%)
Query: 292 ELSAKKRKK--SSSEALFKSFSSAPPLILTCSADKKQIKDKSHVKMGKVKIESETSEKKK 349
+LS K+K E KS + AP ++ KD+S K G K SE +
Sbjct: 2 DLSGVKKKSLLGVKENNKKSSTRAPSPTKRKDRSDEKSKDRSKDK-GATKESSEKDRGRD 60
Query: 350 STLPPFDDIVDPNDSDVEENISSKSDSEQPSPASSSSSSSSSFTPSQTRQQGPLRSIMKD 409
T S SS S S + SSS SSSS S++ RS
Sbjct: 61 KTRKRHS--ASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSS 118
Query: 410 LHSDDNEEESDEVEDNDNDSEMERPVNRGGSRSRRVSLS 448
S ++ +P R +R S S
Sbjct: 119 SSSGSPSPSRRRHDNRRRSRSKSKPPKRDEKERKRRSPS 157
>gi|88973230 PREDICTED: similar to ribonucleic acid binding protein
S1 isoform 3 [Homo sapiens]
Length = 305
Score = 69.3 bits (168), Expect = 9e-12
Identities = 46/106 (43%), Positives = 58/106 (54%), Gaps = 5/106 (4%)
Query: 139 GGDPNRSIHTSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFSKPHK 198
G D R H++SS SSS+ S SSS+SSS SS+S+ SSS SSSSS+SS S SS++
Sbjct: 58 GRDKTRKRHSASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSS 117
Query: 199 LMKEHKEKPSK----DSREHKSAFKEPSRDHNKSSKESSKKPKENK 240
PS+ + R +S K P RD K K S PK K
Sbjct: 118 SSSSGSPSPSRRRHDNRRRSRSKSKPPKRD-EKERKRRSPSPKPTK 162
Score = 57.0 bits (136), Expect = 5e-08
Identities = 40/101 (39%), Positives = 54/101 (53%), Gaps = 7/101 (6%)
Query: 132 RRKLLKAGGDPNRSIHTSSSSS-------SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 184
+R +G RS +S+SSS SSS SSSSS+SS S SSS+S SSSSSSSS S
Sbjct: 64 KRHSASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGS 123
Query: 185 SSSSSSTSFSKPHKLMKEHKEKPSKDSREHKSAFKEPSRDH 225
S S ++ K K + R+ +S +P++ H
Sbjct: 124 PSPSRRRHDNRRRSRSKSKPPKRDEKERKRRSPSPKPTKVH 164
Score = 52.8 bits (125), Expect = 9e-07
Identities = 42/129 (32%), Positives = 52/129 (40%), Gaps = 12/129 (9%)
Query: 137 KAGGDPNRSIHTSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFSKP 196
K G S + S+SS SSS+ S SSS+SSS SS+S+ SSS S+S S
Sbjct: 44 KDKGATKESSEKDRGRDKTRKRHSASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSAS 103
Query: 197 HKLMKEHKEKPSKDSREHKSAFKEPSRDHNKSSKESSKKPKENKPLKEEKIVPKMAFKEP 256
+ + S S S R N+ S KP PK KE
Sbjct: 104 SRSGSSSTSRSSSSSSSSGSPSPSRRRHDNRRRSRSKSKP------------PKRDEKER 151
Query: 257 KPMSKEPKP 265
K S PKP
Sbjct: 152 KRRSPSPKP 160
Score = 40.8 bits (94), Expect = 0.003
Identities = 28/78 (35%), Positives = 36/78 (46%)
Query: 148 TSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFSKPHKLMKEHKEKP 207
+SS+SS S SSS+S SSSSSSSS S S S + S S S + K K P
Sbjct: 99 SSSASSRSGSSSTSRSSSSSSSSGSPSPSRRRHDNRRRSRSKSKPPKRDEKERKRRSPSP 158
Query: 208 SKDSREHKSAFKEPSRDH 225
+ ++DH
Sbjct: 159 KPTKVHIGRLTRNVTKDH 176
Score = 40.0 bits (92), Expect = 0.006
Identities = 38/140 (27%), Positives = 58/140 (41%), Gaps = 17/140 (12%)
Query: 280 APSKRPPISDSEELSAKKRKKSSSEALFKSFSSAPPLILTCSADKKQIKDKSHVKMGKVK 339
+P+KR SD + K K ++ E S++K + +DK+ +
Sbjct: 27 SPTKRKDRSDEKSKDRSKDKGATKE----------------SSEKDRGRDKTRKRHSASS 70
Query: 340 IESETSEKKKSTLPPFDDIVDPNDS-DVEENISSKSDSEQPSPASSSSSSSSSFTPSQTR 398
S T + ST + S + SS+S S S +SSSSSSS S +PS+ R
Sbjct: 71 GSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSPSPSRRR 130
Query: 399 QQGPLRSIMKDLHSDDNEEE 418
RS K +E+E
Sbjct: 131 HDNRRRSRSKSKPPKRDEKE 150
Score = 29.6 bits (65), Expect = 7.8
Identities = 39/159 (24%), Positives = 53/159 (33%), Gaps = 5/159 (3%)
Query: 292 ELSAKKRKK--SSSEALFKSFSSAPPLILTCSADKKQIKDKSHVKMGKVKIESETSEKKK 349
+LS K+K E KS + AP ++ KD+S K G K SE +
Sbjct: 2 DLSGVKKKSLLGVKENNKKSSTRAPSPTKRKDRSDEKSKDRSKDK-GATKESSEKDRGRD 60
Query: 350 STLPPFDDIVDPNDSDVEENISSKSDSEQPSPASSSSSSSSSFTPSQTRQQGPLRSIMKD 409
T S SS S S + SSS SSSS S++ RS
Sbjct: 61 KTRKRHS--ASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSS 118
Query: 410 LHSDDNEEESDEVEDNDNDSEMERPVNRGGSRSRRVSLS 448
S ++ +P R +R S S
Sbjct: 119 SSSGSPSPSRRRHDNRRRSRSKSKPPKRDEKERKRRSPS 157
>gi|169166609 PREDICTED: similar to ribonucleic acid binding protein
S1 isoform 6 [Homo sapiens]
Length = 305
Score = 68.9 bits (167), Expect = 1e-11
Identities = 48/109 (44%), Positives = 62/109 (56%), Gaps = 10/109 (9%)
Query: 132 RRKLLKAGGDPNRSIHTSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSST 191
+R+ +G RS SSS+SSS SS+S+ SSS SSSSS+SS S SSS+S SSSSSSS+
Sbjct: 64 KRRSASSGSSSTRS--RSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSS 121
Query: 192 SFSKPHKLMKEHKEKPSKDSREHKSAFKEPSRDHNKSSKESSKKPKENK 240
P + +++ R +S K P RD K K S PK K
Sbjct: 122 GSPSPSRRRHDNR-------RRSRSKSKPPKRD-EKERKRRSPSPKPTK 162
Score = 63.2 bits (152), Expect = 6e-10
Identities = 45/116 (38%), Positives = 58/116 (50%), Gaps = 22/116 (18%)
Query: 150 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFSKPHKLMKEHKEKPSK 209
S+SS SSS+ S SSS+SSS SS+S+ SSS SSSSS+SS S +S + PS
Sbjct: 67 SASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSPSP 126
Query: 210 DSREHKSAFKEPSRDHNKSSKESSKKPKENKPLKEEKIVPKMAFKEPKPMSKEPKP 265
R H D+ + S+ SK PK ++ KE K S PKP
Sbjct: 127 SRRRH---------DNRRRSRSKSKPPKRDE-------------KERKRRSPSPKP 160
Score = 40.8 bits (94), Expect = 0.003
Identities = 28/78 (35%), Positives = 36/78 (46%)
Query: 148 TSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFSKPHKLMKEHKEKP 207
+SS+SS S SSS+S SSSSSSSS S S S + S S S + K K P
Sbjct: 99 SSSASSRSGSSSTSRSSSSSSSSGSPSPSRRRHDNRRRSRSKSKPPKRDEKERKRRSPSP 158
Query: 208 SKDSREHKSAFKEPSRDH 225
+ ++DH
Sbjct: 159 KPTKVHIGRLTRNVTKDH 176
Score = 40.4 bits (93), Expect = 0.004
Identities = 38/140 (27%), Positives = 58/140 (41%), Gaps = 17/140 (12%)
Query: 280 APSKRPPISDSEELSAKKRKKSSSEALFKSFSSAPPLILTCSADKKQIKDKSHVKMGKVK 339
+P+KR SD + K K ++ E S++K + +DK+ +
Sbjct: 27 SPTKRKDRSDEKSKDRSKDKGATKE----------------SSEKDRGRDKTRKRRSASS 70
Query: 340 IESETSEKKKSTLPPFDDIVDPNDS-DVEENISSKSDSEQPSPASSSSSSSSSFTPSQTR 398
S T + ST + S + SS+S S S +SSSSSSS S +PS+ R
Sbjct: 71 GSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSPSPSRRR 130
Query: 399 QQGPLRSIMKDLHSDDNEEE 418
RS K +E+E
Sbjct: 131 HDNRRRSRSKSKPPKRDEKE 150
>gi|113415994 PREDICTED: similar to ribonucleic acid binding protein
S1 isoform 2 [Homo sapiens]
Length = 305
Score = 68.9 bits (167), Expect = 1e-11
Identities = 48/109 (44%), Positives = 62/109 (56%), Gaps = 10/109 (9%)
Query: 132 RRKLLKAGGDPNRSIHTSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSST 191
+R+ +G RS SSS+SSS SS+S+ SSS SSSSS+SS S SSS+S SSSSSSS+
Sbjct: 64 KRRSASSGSSSTRS--RSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSS 121
Query: 192 SFSKPHKLMKEHKEKPSKDSREHKSAFKEPSRDHNKSSKESSKKPKENK 240
P + +++ R +S K P RD K K S PK K
Sbjct: 122 GSPSPSRRRHDNR-------RRSRSKSKPPKRD-EKERKRRSPSPKPTK 162
Score = 63.2 bits (152), Expect = 6e-10
Identities = 45/116 (38%), Positives = 58/116 (50%), Gaps = 22/116 (18%)
Query: 150 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFSKPHKLMKEHKEKPSK 209
S+SS SSS+ S SSS+SSS SS+S+ SSS SSSSS+SS S +S + PS
Sbjct: 67 SASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSPSP 126
Query: 210 DSREHKSAFKEPSRDHNKSSKESSKKPKENKPLKEEKIVPKMAFKEPKPMSKEPKP 265
R H D+ + S+ SK PK ++ KE K S PKP
Sbjct: 127 SRRRH---------DNRRRSRSKSKPPKRDE-------------KERKRRSPSPKP 160
Score = 40.8 bits (94), Expect = 0.003
Identities = 28/78 (35%), Positives = 36/78 (46%)
Query: 148 TSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFSKPHKLMKEHKEKP 207
+SS+SS S SSS+S SSSSSSSS S S S + S S S + K K P
Sbjct: 99 SSSASSRSGSSSTSRSSSSSSSSGSPSPSRRRHDNRRRSRSKSKPPKRDEKERKRRSPSP 158
Query: 208 SKDSREHKSAFKEPSRDH 225
+ ++DH
Sbjct: 159 KPTKVHIGRLTRNVTKDH 176
Score = 40.4 bits (93), Expect = 0.004
Identities = 38/140 (27%), Positives = 58/140 (41%), Gaps = 17/140 (12%)
Query: 280 APSKRPPISDSEELSAKKRKKSSSEALFKSFSSAPPLILTCSADKKQIKDKSHVKMGKVK 339
+P+KR SD + K K ++ E S++K + +DK+ +
Sbjct: 27 SPTKRKDRSDEKSKDRSKDKGATKE----------------SSEKDRGRDKTRKRRSASS 70
Query: 340 IESETSEKKKSTLPPFDDIVDPNDS-DVEENISSKSDSEQPSPASSSSSSSSSFTPSQTR 398
S T + ST + S + SS+S S S +SSSSSSS S +PS+ R
Sbjct: 71 GSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSPSPSRRR 130
Query: 399 QQGPLRSIMKDLHSDDNEEE 418
RS K +E+E
Sbjct: 131 HDNRRRSRSKSKPPKRDEKE 150
>gi|6857826 RNA-binding protein S1, serine-rich domain [Homo
sapiens]
Length = 305
Score = 68.9 bits (167), Expect = 1e-11
Identities = 48/109 (44%), Positives = 62/109 (56%), Gaps = 10/109 (9%)
Query: 132 RRKLLKAGGDPNRSIHTSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSST 191
+R+ +G RS SSS+SSS SS+S+ SSS SSSSS+SS S SSS+S SSSSSSS+
Sbjct: 64 KRRSASSGSSSTRS--RSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSS 121
Query: 192 SFSKPHKLMKEHKEKPSKDSREHKSAFKEPSRDHNKSSKESSKKPKENK 240
P + +++ R +S K P RD K K S PK K
Sbjct: 122 GSPSPSRRRHDNR-------RRSRSKSKPPKRD-EKERKRRSPSPKPTK 162
Score = 63.2 bits (152), Expect = 6e-10
Identities = 45/116 (38%), Positives = 58/116 (50%), Gaps = 22/116 (18%)
Query: 150 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFSKPHKLMKEHKEKPSK 209
S+SS SSS+ S SSS+SSS SS+S+ SSS SSSSS+SS S +S + PS
Sbjct: 67 SASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSPSP 126
Query: 210 DSREHKSAFKEPSRDHNKSSKESSKKPKENKPLKEEKIVPKMAFKEPKPMSKEPKP 265
R H D+ + S+ SK PK ++ KE K S PKP
Sbjct: 127 SRRRH---------DNRRRSRSKSKPPKRDE-------------KERKRRSPSPKP 160
Score = 40.8 bits (94), Expect = 0.003
Identities = 28/78 (35%), Positives = 36/78 (46%)
Query: 148 TSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFSKPHKLMKEHKEKP 207
+SS+SS S SSS+S SSSSSSSS S S S + S S S + K K P
Sbjct: 99 SSSASSRSGSSSTSRSSSSSSSSGSPSPSRRRHDNRRRSRSKSKPPKRDEKERKRRSPSP 158
Query: 208 SKDSREHKSAFKEPSRDH 225
+ ++DH
Sbjct: 159 KPTKVHIGRLTRNVTKDH 176
Score = 40.4 bits (93), Expect = 0.004
Identities = 38/140 (27%), Positives = 58/140 (41%), Gaps = 17/140 (12%)
Query: 280 APSKRPPISDSEELSAKKRKKSSSEALFKSFSSAPPLILTCSADKKQIKDKSHVKMGKVK 339
+P+KR SD + K K ++ E S++K + +DK+ +
Sbjct: 27 SPTKRKDRSDEKSKDRSKDKGATKE----------------SSEKDRGRDKTRKRRSASS 70
Query: 340 IESETSEKKKSTLPPFDDIVDPNDS-DVEENISSKSDSEQPSPASSSSSSSSSFTPSQTR 398
S T + ST + S + SS+S S S +SSSSSSS S +PS+ R
Sbjct: 71 GSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSPSPSRRR 130
Query: 399 QQGPLRSIMKDLHSDDNEEE 418
RS K +E+E
Sbjct: 131 HDNRRRSRSKSKPPKRDEKE 150
>gi|18379334 RNA-binding protein S1, serine-rich domain [Homo
sapiens]
Length = 305
Score = 68.9 bits (167), Expect = 1e-11
Identities = 48/109 (44%), Positives = 62/109 (56%), Gaps = 10/109 (9%)
Query: 132 RRKLLKAGGDPNRSIHTSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSST 191
+R+ +G RS SSS+SSS SS+S+ SSS SSSSS+SS S SSS+S SSSSSSS+
Sbjct: 64 KRRSASSGSSSTRS--RSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSS 121
Query: 192 SFSKPHKLMKEHKEKPSKDSREHKSAFKEPSRDHNKSSKESSKKPKENK 240
P + +++ R +S K P RD K K S PK K
Sbjct: 122 GSPSPSRRRHDNR-------RRSRSKSKPPKRD-EKERKRRSPSPKPTK 162
Score = 63.2 bits (152), Expect = 6e-10
Identities = 45/116 (38%), Positives = 58/116 (50%), Gaps = 22/116 (18%)
Query: 150 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFSKPHKLMKEHKEKPSK 209
S+SS SSS+ S SSS+SSS SS+S+ SSS SSSSS+SS S +S + PS
Sbjct: 67 SASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSPSP 126
Query: 210 DSREHKSAFKEPSRDHNKSSKESSKKPKENKPLKEEKIVPKMAFKEPKPMSKEPKP 265
R H D+ + S+ SK PK ++ KE K S PKP
Sbjct: 127 SRRRH---------DNRRRSRSKSKPPKRDE-------------KERKRRSPSPKP 160
Score = 40.8 bits (94), Expect = 0.003
Identities = 28/78 (35%), Positives = 36/78 (46%)
Query: 148 TSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFSKPHKLMKEHKEKP 207
+SS+SS S SSS+S SSSSSSSS S S S + S S S + K K P
Sbjct: 99 SSSASSRSGSSSTSRSSSSSSSSGSPSPSRRRHDNRRRSRSKSKPPKRDEKERKRRSPSP 158
Query: 208 SKDSREHKSAFKEPSRDH 225
+ ++DH
Sbjct: 159 KPTKVHIGRLTRNVTKDH 176
Score = 40.4 bits (93), Expect = 0.004
Identities = 38/140 (27%), Positives = 58/140 (41%), Gaps = 17/140 (12%)
Query: 280 APSKRPPISDSEELSAKKRKKSSSEALFKSFSSAPPLILTCSADKKQIKDKSHVKMGKVK 339
+P+KR SD + K K ++ E S++K + +DK+ +
Sbjct: 27 SPTKRKDRSDEKSKDRSKDKGATKE----------------SSEKDRGRDKTRKRRSASS 70
Query: 340 IESETSEKKKSTLPPFDDIVDPNDS-DVEENISSKSDSEQPSPASSSSSSSSSFTPSQTR 398
S T + ST + S + SS+S S S +SSSSSSS S +PS+ R
Sbjct: 71 GSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSPSPSRRR 130
Query: 399 QQGPLRSIMKDLHSDDNEEE 418
RS K +E+E
Sbjct: 131 HDNRRRSRSKSKPPKRDEKE 150
>gi|68299795 chromodomain helicase DNA binding protein 1 [Homo
sapiens]
Length = 1710
Score = 67.4 bits (163), Expect = 3e-11
Identities = 88/324 (27%), Positives = 118/324 (36%), Gaps = 71/324 (21%)
Query: 139 GGDPNRSIHTSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFSKPHK 198
G S+ SS SS S S S+S S S SSS SSS SSS S SS S S S S
Sbjct: 3 GHSDEESVRNSSGESSQSDDDSGSASGSGSGSSSGSSSDGSSSQSGSSDSDSGSES---- 58
Query: 199 LMKEHKEKPSKDSREHKSAFKEPSRDHNKSSKESSKKPKENKPLKEEKIVPKMAFKEPKP 258
E S SRE+K K P D E K ++ I+ K ++ +
Sbjct: 59 --GSQSESESDTSRENKVQAKPPKVD----GAEFWKSSPSILAVQRSAILKK---QQQQQ 109
Query: 259 MSKEPKPDSNLLTITSGQDKKAPSKRPPISDSEELSAKKRKKSSSEALFKSFSSAPPLIL 318
++ + SN SG ++ + S S E+ KRKK E S S +P
Sbjct: 110 QQQQHQASSN-----SGSEEDSSSSEDSDDSSSEV---KRKKHKDEDWQMSGSGSP---- 157
Query: 319 TCSADKKQIKDKSHVKMGKVKIESETSEKKKSTLPPFDDIVDPNDSDVEENISSKSDSEQ 378
ESE +K S D +SD E K+ +
Sbjct: 158 ---------------SQSGSDSESEEEREKSS--------CDETESDYE----PKNKVKS 190
Query: 379 PSPASSSSSSSSSFTPSQTRQQGPLRSIMKDLHSDDNEEESDEVEDNDNDSEMERPVNRG 438
P + S S + Q ++Q D+ EE D+ ED DND R
Sbjct: 191 RKPQNRSKSKNGKKILGQKKRQ------------IDSSEEDDDEEDYDND-------KRS 231
Query: 439 GSRSRRVSLSDGSDSESSSASSPL 462
R V++S D E + S L
Sbjct: 232 SRRQATVNVSYKEDEEMKTDSDDL 255
Score = 42.4 bits (98), Expect = 0.001
Identities = 44/175 (25%), Positives = 68/175 (38%), Gaps = 27/175 (15%)
Query: 132 RRKLLKAGGDPNRSIHTSSSSSSSSSSSSSSSSSSSSSSS--------------SSSSSS 177
R +LK + +SS+S S SSSS S SSS S S S
Sbjct: 98 RSAILKKQQQQQQQQQHQASSNSGSEEDSSSSEDSDDSSSEVKRKKHKDEDWQMSGSGSP 157
Query: 178 SSSSSSS--------SSSSSSTSFSKPHKLMKEHKEKPSKDSREHKSAFKEPSRDHNKSS 229
S S S S SS + S +P +K K + S+ K + R + S
Sbjct: 158 SQSGSDSESEEEREKSSCDETESDYEPKNKVKSRKPQNRSKSKNGKKILGQKKRQIDSSE 217
Query: 230 KESSKKPKEN-KPLKEEKIVPKMAFKEPKPMSKEPKPDSNLLTITSGQDKKAPSK 283
++ ++ +N K + +++KE +E K DS+ L G+D P +
Sbjct: 218 EDDDEEDYDNDKRSSRRQATVNVSYKE----DEEMKTDSDDLLEVCGEDVPQPEE 268
Score = 30.8 bits (68), Expect = 3.5
Identities = 30/133 (22%), Positives = 50/133 (37%), Gaps = 18/133 (13%)
Query: 364 SDVEENISSKSDSEQPSPASSSSSSSSSFTPSQTRQQGPLRSIMKDLHSDDNEEESDEVE 423
SD E +S +S Q S S+S S S + S + G S +SD
Sbjct: 5 SDEESVRNSSGESSQSDDDSGSASGSGSGSSSGSSSDGS--------SSQSGSSDSDSGS 56
Query: 424 DNDNDSEMERPVNRGGSRSRRVSLSDGSDSESSSASSPLHHEPPPPLLKTNNNQILEVKS 483
++ + SE E +R + DG++ SS P +L + IL+ +
Sbjct: 57 ESGSQSESESDTSRENKVQAKPPKVDGAEFWKSS----------PSILAVQRSAILKKQQ 106
Query: 484 PIKQSKSDKQIKN 496
+Q + + N
Sbjct: 107 QQQQQQQHQASSN 119
>gi|27734775 hypothetical protein LOC286499 [Homo sapiens]
Length = 248
Score = 67.4 bits (163), Expect = 3e-11
Identities = 52/185 (28%), Positives = 85/185 (45%), Gaps = 8/185 (4%)
Query: 129 EDFRRKLLKAGGDPNRSIHTSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 188
E+++++L K+ + + + SSS S SSSSSSSS SSSSSS S
Sbjct: 67 ENWKKELEKS----REKLLSGNESSSKKRERKKKRKKKSCRSSSSSSSSDSSSSSSDSED 122
Query: 189 SSTSFSKPHKLMKEHKEKPSKDSREHKSAFKEPSRDHNKSSKESSKKPKENKPLKEEKIV 248
K K K K S+ S + + S K SK+ ++K K+ + L +++
Sbjct: 123 EEKKQGKRRKKKKNRSYKSSQSSTHESESESKESVKKKKKSKDETEKEKDVRSLSKKR-- 180
Query: 249 PKMAFKEPKPMSKEPKPDSNLLTITSGQDKKAPSKRPPISDSEELSAKKR-KKSSSEALF 307
K ++ + KP+S E +S+ + K+ +R + + KK+ KK S +
Sbjct: 181 -KKSYPDDKPLSSESSSESDYEEDVQAKKKRRCEEREQAKEKVKKKKKKQHKKHSKKKKK 239
Query: 308 KSFSS 312
KS SS
Sbjct: 240 KSGSS 244
Score = 51.2 bits (121), Expect = 2e-06
Identities = 54/205 (26%), Positives = 86/205 (41%), Gaps = 55/205 (26%)
Query: 152 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFSKPHKLMKEHKEKPSKDS 211
S + SSS S SSSSSSSS SSSSSS S K K+ K + K +
Sbjct: 82 SGNESSSKKRERKKKRKKKSCRSSSSSSSSDSSSSSSDSEDEEK-----KQGKRRKKKKN 136
Query: 212 REHKSAFKEPSRDHNKSSKESSKKPKENKPLKEEKIVPKMAFKEPKPMSKEPKPDSNLLT 271
R +KS+ +SS E++ K + K+ K E + + ++ +
Sbjct: 137 RSYKSS-------------QSSTHESESE--------SKESVKKKKKSKDETEKEKDVRS 175
Query: 272 ITSGQDKKAPSKRPPISDS-------EELSAKKRKKSSSEALFKSFSSAPPLILTCSADK 324
++ + K P +P S+S E++ AKK+++ ++
Sbjct: 176 LSKKRKKSYPDDKPLSSESSSESDYEEDVQAKKKRRCE--------------------ER 215
Query: 325 KQIKDKSHVKMGKVKIESETSEKKK 349
+Q K+K VK K K + S+KKK
Sbjct: 216 EQAKEK--VKKKKKKQHKKHSKKKK 238
Score = 45.8 bits (107), Expect = 1e-04
Identities = 48/195 (24%), Positives = 84/195 (43%), Gaps = 18/195 (9%)
Query: 324 KKQIKDKSHVKMGKVKIESETSEKKKSTLPPF-DDIVDPNDS-----DVEENISSKSDSE 377
KKQ+++K + E + +E K L + ++ N+S + ++ KS
Sbjct: 45 KKQLENKKTGSKALAEFEEKMNENWKKELEKSREKLLSGNESSSKKRERKKKRKKKSCRS 104
Query: 378 QPSPASSSSSSSSSFTPSQTRQQGPLRS-----IMKDLHSDDNEEESDEVED------ND 426
S +SS SSSSSS + + ++QG R K S +E ES+ E +
Sbjct: 105 SSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHESESESKESVKKKKKSK 164
Query: 427 NDSEMERPVNRGGSRSRRVSLSDGSDSESSSASSPLHHEPPPPLLKTNNNQILEVKSPIK 486
+++E E+ V R S+ R+ S D S S+S + E K + + K +K
Sbjct: 165 DETEKEKDV-RSLSKKRKKSYPDDKPLSSESSSESDYEEDVQAKKKRRCEEREQAKEKVK 223
Query: 487 QSKSDKQIKNGECDK 501
+ K + K+ + K
Sbjct: 224 KKKKKQHKKHSKKKK 238
Score = 38.9 bits (89), Expect = 0.013
Identities = 44/178 (24%), Positives = 76/178 (42%), Gaps = 28/178 (15%)
Query: 198 KLMKEHKEKPSKDSREHKSAFKEPSRDHNKSSKESSKKPKENKPLKEEKIVPKMAFKEPK 257
K + E +EK +++ ++ E SR+ S ESS K +E K +++K +
Sbjct: 56 KALAEFEEKMNENWKKEL----EKSREKLLSGNESSSKKRERKKKRKKKSC--------R 103
Query: 258 PMSKEPKPDSNLLTITSGQDKKAPSKRPPISDSEELSAKKRKKSSSEALFKSFSSAPPLI 317
S DS+ +S D S+ EE KR+K +KS S+
Sbjct: 104 SSSSSSSSDSS----SSSSD----------SEDEEKKQGKRRKKKKNRSYKSSQSSTHES 149
Query: 318 LTCSADKKQIKDKSHVKMGKVKIESETSEKKKSTLPPFDDI--VDPNDSDVEENISSK 373
+ S + + K KS + K K S+K+K + P + ++SD EE++ +K
Sbjct: 150 ESESKESVKKKKKSKDETEKEKDVRSLSKKRKKSYPDDKPLSSESSSESDYEEDVQAK 207
>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
sapiens]
Length = 699
Score = 67.0 bits (162), Expect = 4e-11
Identities = 91/449 (20%), Positives = 164/449 (36%), Gaps = 84/449 (18%)
Query: 120 EKLTFNNPTEDFRRKLLKAGGDPNRSIHTSSSSSSSSSSSSSSSSSSSSSSSS------- 172
E+ + ++ ED +++ ++ G P + + SS S S SSS +
Sbjct: 130 EESSDDDDEEDQKKQPVQKGVKPQAKAAKAPPKKAKSSDSDSDSSSEDEPPKNQKPKITP 189
Query: 173 ---------------SSSSSSSSSSSSSSSSSSTSFSKPHKLMKEHKEKPSKDSREHKSA 217
++ ++ ++SSSSSSS+S S ++ P K + +
Sbjct: 190 VTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSDDSEEEKAAATPKKTVPKKQVV 249
Query: 218 FKEP-------------SRDHNKSSKESSKKPKENKPLKEEKIVPKMAFKEPKPMSKEPK 264
K P S D + +E KKP +NKP + P A K + +P
Sbjct: 250 AKAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSSVPPPSAPPPKKSLGTQP- 308
Query: 265 PDSNLLTITSGQDKKAPSKRPPI------SDSEELSAKKRKKSSSEALFKSFSSAPPLIL 318
KKA K+ P+ SD + S+++ KK ++A+ ++ PP
Sbjct: 309 ------------PKKAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKATTKPPPAK 356
Query: 319 TCSADKKQIKDKSHVKMGKVKIESETSEKKKSTLPPF---DDIVDP-------------- 361
+ D + + + + K S P V P
Sbjct: 357 KAAESSSDSSDSDSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKL 416
Query: 362 ------NDSDVEENISSKSDSEQPSPASSSSSSSSSFTPSQTRQQGPLRSIMKDLHSDDN 415
+ S EE+ SS+ + + A++ +++ S +Q P S +D SD +
Sbjct: 417 LTRKADSSSSEEESSSSEEEKTKKMVATTKPKATAKAALSLPAKQAPQGS--RDSSSDSD 474
Query: 416 EEESDEVEDNDNDSEMER---PVNRGGSRSRRVSLSDGSDSESSSASSPLHHEPPPPLLK 472
S+E E+ + S +++ V G + S+ S G S+S+SS E LK
Sbjct: 475 SSSSEEEEEKTSKSAVKKKPQKVAGGAAPSKPASAKKGKAESSNSSSSDDSSEEEEEKLK 534
Query: 473 TNNNQILEVKSPIKQSKSDKQIKNGECDK 501
+ ++P S +NG+ K
Sbjct: 535 GKGSP--RPQAPKANGTSALTAQNGKAAK 561
Score = 65.9 bits (159), Expect = 1e-10
Identities = 90/390 (23%), Positives = 145/390 (37%), Gaps = 63/390 (16%)
Query: 136 LKAGGDPNRSIHTSSSSSSSSSSSSSSSSSSSSSSSSSSSSS-----------------S 178
LK+ P R + + + + +SSS S SS
Sbjct: 58 LKSAKVPERKLQANGPVAKKAKKKASSSDSEDSSEEEEEVQGPPAKKAAVPAKRVGLPPG 117
Query: 179 SSSSSSSSSSSSTSFSKPHKLMKEHKEKPSKDSREHKSAFKEPSRDHNKSSKESSKKPKE 238
+++ +S SSSS S + K+ K + A K P + KSS S E
Sbjct: 118 KAAAKASESSSSEESSDDDDEEDQKKQPVQKGVKPQAKAAKAPPK-KAKSSDSDSDSSSE 176
Query: 239 NKPLKEEKIVPKMAFKEPKPMSK-EPKPDSNLLTITSGQDKKAPSKRPPISDSEELSAKK 297
++P K +K PK+ K +K PKP I +G+ + S S S++ +K
Sbjct: 177 DEPPKNQK--PKITPVTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSDDSEEEK 234
Query: 298 RKKSSSEALFKSFSSAPPLILTCSADKKQIKDKSHVKMGKVKIESETSEKKKSTLPPFDD 357
++A P KK + K V VK + + K S+
Sbjct: 235 -------------AAATP--------KKTVPKKQVVAKAPVKAATTPTRKSSSS------ 267
Query: 358 IVDPNDSDVEENISSKSDSEQPSPASSSSSSSSSFTPSQTRQQGPLRSIMKDLHSDDNEE 417
+ + SD EE K +P P SS S+ Q P +++ K + +E+
Sbjct: 268 --EDSSSDEEEE-QKKPMKNKPGPYSSVPPPSAPPPKKSLGTQPPKKAVEKQQPVESSED 324
Query: 418 ESDEVEDNDNDSEMERPVNRGGSRS---------RRVSLSDGSDSESSSASSPLHHEPPP 468
SDE D+ ++ E + P S++ S SD SDS+SS +P
Sbjct: 325 SSDE-SDSSSEEEKKPPTKAVVSKATTKPPPAKKAAESSSDSSDSDSSE-DDEAPSKPAG 382
Query: 469 PLLKTNNNQILEVKSP-IKQSKSDKQIKNG 497
++N + KSP +K + + KQ G
Sbjct: 383 TTKNSSNKPAVTTKSPAVKPAAAPKQPVGG 412
Score = 47.8 bits (112), Expect = 3e-05
Identities = 75/341 (21%), Positives = 131/341 (38%), Gaps = 69/341 (20%)
Query: 137 KAGGDPNRSIHTSSSSSSSSSSSSSSSS--------SSSSSSSSSSSSSSSSSSSSSSSS 188
K + + + +S SS S SSS S +++ + ++ SSS SS S
Sbjct: 310 KKAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKATTKPPPAKKAAESSSDSSDSD 369
Query: 189 SS---TSFSKPHKLMKEHKEKPSKDSR----EHKSAFKEPSRDHNK---SSKESSKKPKE 238
SS + SKP K KP+ ++ + +A K+P K +SS +E
Sbjct: 370 SSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKLLTRKADSSSSEEE 429
Query: 239 NKPLKEEKIVPKMAFKEPKPMSKEPKPDSNLLTITSGQDKKAP-SKRPPISDSEELSAKK 297
+ +EEK +A +PK +K S K+AP R SDS+ S+++
Sbjct: 430 SSSSEEEKTKKMVATTKPKATAK---------AALSLPAKQAPQGSRDSSSDSDSSSSEE 480
Query: 298 RKKSSSEALFKSFSSAPPLILTCSADKKQIKDKSHVKMGKVKIESETSEKKKSTLPPFDD 357
++ +S++ K P + +A K K K K ES S
Sbjct: 481 EEEKTSKSAVK---KKPQKVAGGAAPSKPASAK------KGKAESSNSSSS--------- 522
Query: 358 IVDPNDSDVEENISSKSDSEQPSPASSSSSSSSSFTPSQTRQQGPLRSIMKDLHSDDNEE 417
D + + EE + K P P + ++ +S+ T + + ++EE
Sbjct: 523 --DDSSEEEEEKLKGKG---SPRPQAPKANGTSALTAQNGKA------------AKNSEE 565
Query: 418 ESDEVEDNDNDSEMERPVNRGGSRSRRVSLSDGSDSESSSA 458
E +E + V++ GS +R ++E+ A
Sbjct: 566 EEEE------KKKAAVVVSKSGSLKKRKQNEAAKEAETPQA 600
Score = 40.4 bits (93), Expect = 0.004
Identities = 33/138 (23%), Positives = 60/138 (43%), Gaps = 19/138 (13%)
Query: 371 SSKSDSEQPSPASSSSSSSSSFTPSQTRQQGPLRSIMKDLHSDDNEEESDEVEDNDNDSE 430
S DS + + + P++ P ++ K S +EE SD D+D + +
Sbjct: 85 SDSEDSSEEEEEVQGPPAKKAAVPAKRVGLPPGKAAAKASESSSSEESSD---DDDEEDQ 141
Query: 431 MERPVNRG-------GSRSRRVSLSDGSDSESSSASSPLHHEPP---PPLLKTNNNQILE 480
++PV +G + + S SDS+SSS P ++ P P +K +
Sbjct: 142 KKQPVQKGVKPQAKAAKAPPKKAKSSDSDSDSSSEDEPPKNQKPKITPVTVKA------Q 195
Query: 481 VKSPIKQSKSDKQIKNGE 498
K+P K +++ +I NG+
Sbjct: 196 TKAPPKPARAAPKIANGK 213
Score = 33.5 bits (75), Expect = 0.54
Identities = 27/124 (21%), Positives = 49/124 (39%), Gaps = 2/124 (1%)
Query: 139 GGDPNR--SIHTSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFSKP 196
G P++ S + SS+SSSS SS S + ++ +S+ + K
Sbjct: 500 GAAPSKPASAKKGKAESSNSSSSDDSSEEEEEKLKGKGSPRPQAPKANGTSALTAQNGKA 559
Query: 197 HKLMKEHKEKPSKDSREHKSAFKEPSRDHNKSSKESSKKPKENKPLKEEKIVPKMAFKEP 256
K +E +E+ K + + R N+++KE+ + L+ PK E
Sbjct: 560 AKNSEEEEEEKKKAAVVVSKSGSLKKRKQNEAAKEAETPQAKKIKLQTPNTFPKRKKGEK 619
Query: 257 KPMS 260
+ S
Sbjct: 620 RASS 623
>gi|217330641 IWS1 homolog [Homo sapiens]
Length = 819
Score = 67.0 bits (162), Expect = 4e-11
Identities = 84/355 (23%), Positives = 133/355 (37%), Gaps = 55/355 (15%)
Query: 136 LKAGGDPNRSIHTSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS----SSSSSST 191
L A + +H S S S + +S S + + S S S + S S +
Sbjct: 77 LNASDSESEELHRQKDSDSESEERAEPPASDSENEDVNQHGSDSESEETRKLPGSDSENE 136
Query: 192 SFSKPHKLMKEHKE---KPSKDSREHKSAFKEPSRDHNKSSKESSKKPKENKPLKEEKIV 248
H E+++ P+ DS E + K P+ D S E + KP+ + EE
Sbjct: 137 ELLNGHASDSENEDVGKHPASDS-EIEELQKSPASD---SETEDALKPQISDSESEEPPR 192
Query: 249 PKMAFKEPKPMSKEPKPDSNLLTITSGQDKKAPSKRPP---ISDSEELSAKKRKKSSSEA 305
+ + E + K DS + Q + S+ PP SDSE K + S SE
Sbjct: 193 HQASDSENEEPPKPRMSDSESEELPKPQVSDSESEEPPRHQASDSENEELPKPRISDSE- 251
Query: 306 LFKSFSSAPPLILTCSADKKQIKDKSHVKMGKVKIESETSEKKKSTLPPFDDIVDPNDSD 365
S PP + Q D + ++ K +I SE PP + D + +
Sbjct: 252 -----SEDPP--------RHQASDSENEELPKPRISDSESED-----PPRNQASDSENEE 293
Query: 366 VEENISSKSDSEQPS--PASSSSSSSSSF--------TPSQTRQQGPLRSIMKD------ 409
+ + S S+SE P PAS S + +S S +G + D
Sbjct: 294 LPKPRVSDSESEGPQKGPASDSETEDASRHKQKPESDDDSDRENKGEDTEMQNDSFHSDS 353
Query: 410 ------LHSDDNEEESDEVEDNDNDSEMERPVNRGGSRSRRVSLSDGSDSESSSA 458
HS D+EEE + + D+D + + ++ + LSD D E +SA
Sbjct: 354 HMDRKKFHSSDSEEEEHKKQKMDSDEDEKEGEEEKVAKRKAAVLSDSEDEEKASA 408
Score = 53.5 bits (127), Expect = 5e-07
Identities = 67/295 (22%), Positives = 103/295 (34%), Gaps = 47/295 (15%)
Query: 142 PNRSIHTSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFSKPHKLMK 201
P I S S + +S S + S S S +S S + S+
Sbjct: 269 PKPRISDSESEDPPRNQASDSENEELPKPRVSDSESEGPQKGPASDSETEDASR------ 322
Query: 202 EHKEKPSKDS---REHKSAFKEPSRDHNKSSKESSKKPKENKPLKEEKIVPKMAFKEPKP 258
HK+KP D RE+K E D S +K + +EE+
Sbjct: 323 -HKQKPESDDDSDRENKGEDTEMQNDSFHSDSHMDRKKFHSSDSEEEE------------ 369
Query: 259 MSKEPKPDSNLLTITSGQDKKAPSKRPPISDSEELSAKKRKKSSSEALFKSFSSAPPLIL 318
K+ K DS+ ++K A K +SDSE+ KKS + S A
Sbjct: 370 -HKKQKMDSDEDEKEGEEEKVAKRKAAVLSDSEDEEKASAKKS------RVVSDADDSDS 422
Query: 319 TCSADKKQIKDKSHVKMGKVKIESETSEKKKSTLPPFDDIVDPNDSDVEENISSKSDSEQ 378
+DK ++K+ + + E S+KK F D + EEN+ + E
Sbjct: 423 DAVSDKSGKREKTIASDSEEEAGKELSDKKNEEKDLFGS--DSESGNEEENLIADIFGE- 479
Query: 379 PSPASSSSSSSSSFTPSQTRQQGPLRSIMKDLHSDDNEEESDEVEDNDNDSEMER 433
S FT +DL + E + E ED+D+D ++R
Sbjct: 480 -----SGDEEEEEFTGFN----------QEDLEEEKGETQVKEAEDSDSDDNIKR 519
Score = 42.7 bits (99), Expect = 9e-04
Identities = 72/310 (23%), Positives = 121/310 (39%), Gaps = 60/310 (19%)
Query: 207 PSKDSREHKSAFKEP-SRDHNKSSKESSKKPKENKPLKEEKIVPKMAFKEPKPMSKEPKP 265
P +D R+ S ++ + H+ S S ++ EN+ E +PK
Sbjct: 18 PVQDERDSGSDGEDDVNEQHSGSDTGSVERHSENETSDREDGLPKGHH------------ 65
Query: 266 DSNLLTITSGQDKKAPSKRPPISDSEELSAKKRKKSSSEALFKSFSSAPPLILTCSADKK 325
+T ++ + + S+SEEL +K S SE + PP + + D
Sbjct: 66 ------VTDSENDEPLNLNASDSESEELHRQKDSDSESEE-----RAEPPASDSENEDVN 114
Query: 326 QIKDKSHVKMGKVKIESETSEKKKSTLPPFDDIVDPNDSDVEENISSK---SDSE----Q 378
Q S ESE + K + +++++ + SD E K SDSE Q
Sbjct: 115 QHGSDS---------ESEETRKLPGSDSENEELLNGHASDSENEDVGKHPASDSEIEELQ 165
Query: 379 PSPASSSSSSSSSFTP-SQTRQQGPLRSIMKDLHSDD------NEEESDEV-EDNDNDSE 430
SPAS S + + S + + P R D +++ ++ ES+E+ + +DSE
Sbjct: 166 KSPASDSETEDALKPQISDSESEEPPRHQASDSENEEPPKPRMSDSESEELPKPQVSDSE 225
Query: 431 MERPVNRGGSRSR-------RVSLSDGSDSESSSASSPLHHEPPPPLLKTNNNQILEVKS 483
E P S S R+S S+ D AS + E P P + + E +
Sbjct: 226 SEEPPRHQASDSENEELPKPRISDSESEDPPRHQASDSENEELPKPRISDS-----ESED 280
Query: 484 PIKQSKSDKQ 493
P + SD +
Sbjct: 281 PPRNQASDSE 290
>gi|154146223 splicing factor, arginine/serine-rich 130 [Homo
sapiens]
Length = 805
Score = 67.0 bits (162), Expect = 4e-11
Identities = 85/317 (26%), Positives = 138/317 (43%), Gaps = 43/317 (13%)
Query: 149 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFSKPHKLMKEHKEKPS 208
S SSSS SSSS+S +SS+SS+ SSSS SSSS SS +SS SSS K H + K
Sbjct: 510 SGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKAR 569
Query: 209 KD-SREHKSAFKEPS-------RDHNKSSKES--SKKPKENKPLKEEKIVPKMAFKEPKP 258
+ SR + K S RD +S++ S ++ + P +E + +
Sbjct: 570 RSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERRRNRSPSRERR----------RS 619
Query: 259 MSKEPKPDSNLLTITSGQD-KKAPSKRPPISDSE-----ELSAKKRKKSSSEALFKSFSS 312
S+ +N + + +D +K +R +S + E ++RKK S ++ K
Sbjct: 620 RSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKERSRSIDKD-RK 678
Query: 313 APPLILTCSADKKQIKDKSHVKMGKVKIESETSEKKKSTLPPFDDI------VDPNDSDV 366
DK++ K K K K + + ++K+ + F + +DS
Sbjct: 679 KKDKEREREQDKRKEKQKREEKDFKFSSQDDRLKRKRESERTFSRSGSISVKIIRHDSRQ 738
Query: 367 EENISSKSDSEQPSPASSSSSSSSSFTPSQTRQQGPLRSIMKDLHSDDNEEESDEVEDND 426
+ S+ DS++ S S SS SSS +P +++ + K HS S VE +
Sbjct: 739 DSKKSTTKDSKKHS-GSDSSGRSSSESPGSSKE----KKAKKPKHS-----RSRSVEKSQ 788
Query: 427 NDSEMERPVNRGGSRSR 443
+ ++ SRSR
Sbjct: 789 RSGKKASRKHKSKSRSR 805
Score = 52.4 bits (124), Expect = 1e-06
Identities = 67/323 (20%), Positives = 125/323 (38%), Gaps = 21/323 (6%)
Query: 142 PNRSIHTSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS-SSSSTSFSKPHKLM 200
PN + S S SSSS SSSS+S +SS+SS+ SSSS S S
Sbjct: 486 PNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRT 545
Query: 201 KEHKEKPSKDSREHKS------AFKEPSRDHNKSSKESSKKPKENKPLKEEKIVPKMAFK 254
P + R +S A + SR +++ K S + + +++ + + + +
Sbjct: 546 SSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVK--IRDRRRSNRNSIE 603
Query: 255 EPKPMSKEPKPDSNLLTITSGQDKKAPSKRPPISDSEELSAKKRKKSSSEALFKSFSSAP 314
+ ++ P + S + + R D ++ ++ S + K +
Sbjct: 604 RERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAK-- 661
Query: 315 PLILTCSADKKQIKDKSHVKMGKVKIESETSEKKKSTLPPFDDIVDPNDSDVEENISSKS 374
++K+ + +S K K K + E+ K + D S ++ + K
Sbjct: 662 ------EQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDDRLKRKR 715
Query: 375 DSEQP-SPASSSSSSSSSFTPSQTRQQGPLRSIMKDLHSDDNEEESDEVEDNDNDSEMER 433
+SE+ S + S S Q ++ + K SD + S E + + + ++
Sbjct: 716 ESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESPGSSKEKKAKK 775
Query: 434 PVNRGGSRSRRVSLSDGSDSESS 456
P + SRSR V S S ++S
Sbjct: 776 PKH---SRSRSVEKSQRSGKKAS 795
Score = 42.7 bits (99), Expect = 9e-04
Identities = 68/333 (20%), Positives = 118/333 (35%), Gaps = 33/333 (9%)
Query: 137 KAGGDPNRSIHTSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFSKP 196
+A GD + + ++S S S SSSS SSSS+S +SSTS
Sbjct: 473 EADGDVVNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTS---- 528
Query: 197 HKLMKEHKEKPSKDSREHKSAFKEPSRDHNKSSKESSKKPKENKPLKEEKIVPKMAFKEP 256
S S++ S SS+ SS K K+ + K
Sbjct: 529 --------------STVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTI-KARRSRS 573
Query: 257 KPMSKEPKPDSNLLTITSGQDKKAPSKRPPISDSEELS---AKKRKKSSSEALFKSFSSA 313
+ S+ K +SN + ++ S R I + +++R++S S + + + A
Sbjct: 574 RSYSRRIKIESNRARVKIRDRRR--SNRNSIERERRRNRSPSRERRRSRSRSRDRRTNRA 631
Query: 314 PPLILTCSADKKQIKDKSHVKMG---KVKIESETSEKKKSTLPPFDDIVDPNDSDVEENI 370
+ S D+++I D+ G K K E++ E+KK D D + E
Sbjct: 632 S---RSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQ 688
Query: 371 SSKSDSEQPSPASSSSSSSSSFTPSQTRQQGPLRSIMKDLHSDDNEEESDEVEDNDNDSE 430
+ + ++ SS R++ R+ + D +D+ +
Sbjct: 689 DKRKEKQKREEKDFKFSSQDD---RLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTT 745
Query: 431 MERPVNRGGSRSRRVSLSDGSDSESSSASSPLH 463
+ + G S R S S+ A P H
Sbjct: 746 KDSKKHSGSDSSGRSSSESPGSSKEKKAKKPKH 778
>gi|154146193 splicing factor, arginine/serine-rich 130 [Homo
sapiens]
Length = 805
Score = 67.0 bits (162), Expect = 4e-11
Identities = 85/317 (26%), Positives = 138/317 (43%), Gaps = 43/317 (13%)
Query: 149 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFSKPHKLMKEHKEKPS 208
S SSSS SSSS+S +SS+SS+ SSSS SSSS SS +SS SSS K H + K
Sbjct: 510 SGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKAR 569
Query: 209 KD-SREHKSAFKEPS-------RDHNKSSKES--SKKPKENKPLKEEKIVPKMAFKEPKP 258
+ SR + K S RD +S++ S ++ + P +E + +
Sbjct: 570 RSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERRRNRSPSRERR----------RS 619
Query: 259 MSKEPKPDSNLLTITSGQD-KKAPSKRPPISDSE-----ELSAKKRKKSSSEALFKSFSS 312
S+ +N + + +D +K +R +S + E ++RKK S ++ K
Sbjct: 620 RSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKERSRSIDKD-RK 678
Query: 313 APPLILTCSADKKQIKDKSHVKMGKVKIESETSEKKKSTLPPFDDI------VDPNDSDV 366
DK++ K K K K + + ++K+ + F + +DS
Sbjct: 679 KKDKEREREQDKRKEKQKREEKDFKFSSQDDRLKRKRESERTFSRSGSISVKIIRHDSRQ 738
Query: 367 EENISSKSDSEQPSPASSSSSSSSSFTPSQTRQQGPLRSIMKDLHSDDNEEESDEVEDND 426
+ S+ DS++ S S SS SSS +P +++ + K HS S VE +
Sbjct: 739 DSKKSTTKDSKKHS-GSDSSGRSSSESPGSSKE----KKAKKPKHS-----RSRSVEKSQ 788
Query: 427 NDSEMERPVNRGGSRSR 443
+ ++ SRSR
Sbjct: 789 RSGKKASRKHKSKSRSR 805
Score = 52.4 bits (124), Expect = 1e-06
Identities = 67/323 (20%), Positives = 125/323 (38%), Gaps = 21/323 (6%)
Query: 142 PNRSIHTSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS-SSSSTSFSKPHKLM 200
PN + S S SSSS SSSS+S +SS+SS+ SSSS S S
Sbjct: 486 PNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRT 545
Query: 201 KEHKEKPSKDSREHKS------AFKEPSRDHNKSSKESSKKPKENKPLKEEKIVPKMAFK 254
P + R +S A + SR +++ K S + + +++ + + + +
Sbjct: 546 SSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVK--IRDRRRSNRNSIE 603
Query: 255 EPKPMSKEPKPDSNLLTITSGQDKKAPSKRPPISDSEELSAKKRKKSSSEALFKSFSSAP 314
+ ++ P + S + + R D ++ ++ S + K +
Sbjct: 604 RERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAK-- 661
Query: 315 PLILTCSADKKQIKDKSHVKMGKVKIESETSEKKKSTLPPFDDIVDPNDSDVEENISSKS 374
++K+ + +S K K K + E+ K + D S ++ + K
Sbjct: 662 ------EQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDDRLKRKR 715
Query: 375 DSEQP-SPASSSSSSSSSFTPSQTRQQGPLRSIMKDLHSDDNEEESDEVEDNDNDSEMER 433
+SE+ S + S S Q ++ + K SD + S E + + + ++
Sbjct: 716 ESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESPGSSKEKKAKK 775
Query: 434 PVNRGGSRSRRVSLSDGSDSESS 456
P + SRSR V S S ++S
Sbjct: 776 PKH---SRSRSVEKSQRSGKKAS 795
Score = 42.7 bits (99), Expect = 9e-04
Identities = 68/333 (20%), Positives = 118/333 (35%), Gaps = 33/333 (9%)
Query: 137 KAGGDPNRSIHTSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFSKP 196
+A GD + + ++S S S SSSS SSSS+S +SSTS
Sbjct: 473 EADGDVVNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTS---- 528
Query: 197 HKLMKEHKEKPSKDSREHKSAFKEPSRDHNKSSKESSKKPKENKPLKEEKIVPKMAFKEP 256
S S++ S SS+ SS K K+ + K
Sbjct: 529 --------------STVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTI-KARRSRS 573
Query: 257 KPMSKEPKPDSNLLTITSGQDKKAPSKRPPISDSEELS---AKKRKKSSSEALFKSFSSA 313
+ S+ K +SN + ++ S R I + +++R++S S + + + A
Sbjct: 574 RSYSRRIKIESNRARVKIRDRRR--SNRNSIERERRRNRSPSRERRRSRSRSRDRRTNRA 631
Query: 314 PPLILTCSADKKQIKDKSHVKMG---KVKIESETSEKKKSTLPPFDDIVDPNDSDVEENI 370
+ S D+++I D+ G K K E++ E+KK D D + E
Sbjct: 632 S---RSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQ 688
Query: 371 SSKSDSEQPSPASSSSSSSSSFTPSQTRQQGPLRSIMKDLHSDDNEEESDEVEDNDNDSE 430
+ + ++ SS R++ R+ + D +D+ +
Sbjct: 689 DKRKEKQKREEKDFKFSSQDD---RLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTT 745
Query: 431 MERPVNRGGSRSRRVSLSDGSDSESSSASSPLH 463
+ + G S R S S+ A P H
Sbjct: 746 KDSKKHSGSDSSGRSSSESPGSSKEKKAKKPKH 778
>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
[Homo sapiens]
Length = 624
Score = 66.6 bits (161), Expect = 6e-11
Identities = 84/359 (23%), Positives = 142/359 (39%), Gaps = 39/359 (10%)
Query: 129 EDFRRKLLKAGGDPNRSIHTSSSSSSSSSSSSSSSSSSSSSSSSSSSSS----SSSSSSS 184
E+ +++ +A + +I S S+ S S + S S SSS S S S S S
Sbjct: 276 EEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRS 335
Query: 185 SSSSSSTSFSKPHKLMKEHKEKPSKDSREHKSAFKEPSRDHNKSSKESSKKPKENKPLKE 244
S + S S K + K +K SK KS + SRD K ++E K+ + K
Sbjct: 336 RSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDR 395
Query: 245 EKIVPKMAFKEPKPMSKEPKPDSNLLTITSGQDKKAPSKRPPISDSEELSAKKRKKSSSE 304
EK + K KE + N +D+ ++ D E+ ++R+K +
Sbjct: 396 EK-----EREREKEREKEKERGKN-------KDRDKEREKDREKDKEKDREREREKEHEK 443
Query: 305 ALFKSFSSAPPLILTCSADKKQIKDKSHVKMGKVKIESETSEKKKSTLPPFD-DIVDPND 363
K +K+Q K+K K +I+ + + KKS PP + +
Sbjct: 444 DRDK------------EKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSR 491
Query: 364 SDVEENISSKSDSEQPSPASSSS---SSSSSFTPSQTRQQGPLRSIMKDLHSDDNE-EES 419
S E +S S SP +S + SS S +P ++ R +D S+ E E S
Sbjct: 492 SSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERS 551
Query: 420 DEVEDNDNDSEMERPVNRGGSRSRRVSLSDGSDSESSSASSPLHHEPPPPLLKTNNNQI 478
+ + ND + + + + S + + + SS S + + P +T N+I
Sbjct: 552 TSMRKSSNDRDGKEKLEK---NSTSLKEKEHNKEPDSSVSKEVDDKDAP---RTEENKI 604
Score = 40.8 bits (94), Expect = 0.003
Identities = 43/143 (30%), Positives = 61/143 (42%), Gaps = 7/143 (4%)
Query: 130 DFRRKLLKAGGDPNRSIHTSSSSSSSSSSSSSSSSSSSS-SSSSSSSSSSSSSSSSSSSS 188
D +RK K P RS + S S SSS S SSS S +S + SS S S S
Sbjct: 468 DEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRS 527
Query: 189 SSTSFSKPHKLMKEHKEKPSKDSREHKSAFKEPSRDHNKSSK--ESSKKPKENKPLKE-E 245
+ K K KE + RE ++ ++ S D + K ++S KE + KE +
Sbjct: 528 RN---KKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPD 584
Query: 246 KIVPKMAFKEPKPMSKEPKPDSN 268
V K + P ++E K N
Sbjct: 585 SSVSKEVDDKDAPRTEENKIQHN 607
>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
[Homo sapiens]
Length = 508
Score = 66.6 bits (161), Expect = 6e-11
Identities = 84/359 (23%), Positives = 142/359 (39%), Gaps = 39/359 (10%)
Query: 129 EDFRRKLLKAGGDPNRSIHTSSSSSSSSSSSSSSSSSSSSSSSSSSSSS----SSSSSSS 184
E+ +++ +A + +I S S+ S S + S S SSS S S S S S
Sbjct: 160 EEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRS 219
Query: 185 SSSSSSTSFSKPHKLMKEHKEKPSKDSREHKSAFKEPSRDHNKSSKESSKKPKENKPLKE 244
S + S S K + K +K SK KS + SRD K ++E K+ + K
Sbjct: 220 RSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDR 279
Query: 245 EKIVPKMAFKEPKPMSKEPKPDSNLLTITSGQDKKAPSKRPPISDSEELSAKKRKKSSSE 304
EK + K KE + N +D+ ++ D E+ ++R+K +
Sbjct: 280 EK-----EREREKEREKEKERGKN-------KDRDKEREKDREKDKEKDREREREKEHEK 327
Query: 305 ALFKSFSSAPPLILTCSADKKQIKDKSHVKMGKVKIESETSEKKKSTLPPFD-DIVDPND 363
K +K+Q K+K K +I+ + + KKS PP + +
Sbjct: 328 DRDK------------EKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSR 375
Query: 364 SDVEENISSKSDSEQPSPASSSS---SSSSSFTPSQTRQQGPLRSIMKDLHSDDNE-EES 419
S E +S S SP +S + SS S +P ++ R +D S+ E E S
Sbjct: 376 SSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERS 435
Query: 420 DEVEDNDNDSEMERPVNRGGSRSRRVSLSDGSDSESSSASSPLHHEPPPPLLKTNNNQI 478
+ + ND + + + + S + + + SS S + + P +T N+I
Sbjct: 436 TSMRKSSNDRDGKEKLEK---NSTSLKEKEHNKEPDSSVSKEVDDKDAP---RTEENKI 488
Score = 40.8 bits (94), Expect = 0.003
Identities = 43/143 (30%), Positives = 61/143 (42%), Gaps = 7/143 (4%)
Query: 130 DFRRKLLKAGGDPNRSIHTSSSSSSSSSSSSSSSSSSSS-SSSSSSSSSSSSSSSSSSSS 188
D +RK K P RS + S S SSS S SSS S +S + SS S S S
Sbjct: 352 DEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRS 411
Query: 189 SSTSFSKPHKLMKEHKEKPSKDSREHKSAFKEPSRDHNKSSK--ESSKKPKENKPLKE-E 245
+ K K KE + RE ++ ++ S D + K ++S KE + KE +
Sbjct: 412 RN---KKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPD 468
Query: 246 KIVPKMAFKEPKPMSKEPKPDSN 268
V K + P ++E K N
Sbjct: 469 SSVSKEVDDKDAPRTEENKIQHN 491
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.305 0.121 0.331
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,769,458
Number of Sequences: 37866
Number of extensions: 1314836
Number of successful extensions: 52928
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 993
Number of HSP's successfully gapped in prelim test: 970
Number of HSP's that attempted gapping in prelim test: 15457
Number of HSP's gapped (non-prelim): 15101
length of query: 568
length of database: 18,247,518
effective HSP length: 108
effective length of query: 460
effective length of database: 14,157,990
effective search space: 6512675400
effective search space used: 6512675400
T: 11
A: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.