BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|155030244 vezatin, adherens junctions transmembrane protein [Homo sapiens] (779 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|155030244 vezatin, adherens junctions transmembrane protein [... 1553 0.0 gi|122937396 coiled-coil domain containing 150 [Homo sapiens] 46 2e-04 gi|51243032 oxysterol-binding protein-like protein 8 isoform b [... 43 0.001 gi|18079218 oxysterol-binding protein-like protein 8 isoform a [... 43 0.001 gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 42 0.002 gi|46048234 nucleolar protein 8 [Homo sapiens] 42 0.003 gi|42794779 myosin 18A isoform b [Homo sapiens] 40 0.006 gi|28416946 myosin 18A isoform a [Homo sapiens] 40 0.006 gi|60302875 shugoshin-like 1 isoform A1 [Homo sapiens] 39 0.024 gi|60302870 shugoshin-like 1 isoform A2 [Homo sapiens] 39 0.024 gi|149363642 coiled-coil domain containing 144A [Homo sapiens] 37 0.054 gi|7019419 guanine nucleotide binding protein-like 2 (nucleolar)... 36 0.12 gi|29789058 WW and C2 domain containing 1 isoform 3 [Homo sapiens] 36 0.12 gi|242247257 WW and C2 domain containing 1 isoform 2 [Homo sapiens] 36 0.12 gi|242247251 WW and C2 domain containing 1 isoform 1 [Homo sapiens] 36 0.12 gi|50658069 phosphodiesterase 4D interacting protein isoform 2 [... 36 0.12 gi|50658071 phosphodiesterase 4D interacting protein isoform 5 [... 36 0.12 gi|157311604 phosphodiesterase 4D interacting protein isoform 1 ... 36 0.12 gi|4502443 dystonin isoform 1e precursor [Homo sapiens] 36 0.12 gi|12711674 UPF3 regulator of nonsense transcripts homolog B iso... 36 0.12 gi|237858619 polyamine modulated factor 1 binding protein 1 isof... 36 0.16 gi|154277116 spectrin repeat containing, nuclear envelope 1 isof... 36 0.16 gi|9257180 adducin 2 isoform c [Homo sapiens] 36 0.16 gi|9257192 adducin 2 isoform a [Homo sapiens] 36 0.16 gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens] 35 0.20 gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens] 35 0.20 gi|18375528 UPF3 regulator of nonsense transcripts homolog B iso... 35 0.20 gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof... 35 0.20 gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isof... 35 0.20 gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isof... 35 0.20 >gi|155030244 vezatin, adherens junctions transmembrane protein [Homo sapiens] Length = 779 Score = 1553 bits (4022), Expect = 0.0 Identities = 779/779 (100%), Positives = 779/779 (100%) Query: 1 MTPEFDEEVVFENSPLYQYLQDLGHTDFEICSSLSPKTEKCTTEGQQKPPTRVLPKQGIL 60 MTPEFDEEVVFENSPLYQYLQDLGHTDFEICSSLSPKTEKCTTEGQQKPPTRVLPKQGIL Sbjct: 1 MTPEFDEEVVFENSPLYQYLQDLGHTDFEICSSLSPKTEKCTTEGQQKPPTRVLPKQGIL 60 Query: 61 LKVAETIKSWIFFSQCNKKDDLLHKLDIGFRLDSLHTILQQEVLLQEDVELIELLDPSIL 120 LKVAETIKSWIFFSQCNKKDDLLHKLDIGFRLDSLHTILQQEVLLQEDVELIELLDPSIL Sbjct: 61 LKVAETIKSWIFFSQCNKKDDLLHKLDIGFRLDSLHTILQQEVLLQEDVELIELLDPSIL 120 Query: 121 SAGQSQQQENGHLPTLCSLATPNIWDLSMLFAFISLLVMLPTWWIVSSWLVWGVILFVYL 180 SAGQSQQQENGHLPTLCSLATPNIWDLSMLFAFISLLVMLPTWWIVSSWLVWGVILFVYL Sbjct: 121 SAGQSQQQENGHLPTLCSLATPNIWDLSMLFAFISLLVMLPTWWIVSSWLVWGVILFVYL 180 Query: 181 VIRALRLWRTAKLQVTLKKYSVHLEDMATNSRAFTNLVRKALRLIQETEVISRGFTLVSA 240 VIRALRLWRTAKLQVTLKKYSVHLEDMATNSRAFTNLVRKALRLIQETEVISRGFTLVSA Sbjct: 181 VIRALRLWRTAKLQVTLKKYSVHLEDMATNSRAFTNLVRKALRLIQETEVISRGFTLVSA 240 Query: 241 ACPFNKAGQHPSQHLIGLRKAVYRTLRANFQAARLATLYMLKNYPLNSESDNVTNYICVV 300 ACPFNKAGQHPSQHLIGLRKAVYRTLRANFQAARLATLYMLKNYPLNSESDNVTNYICVV Sbjct: 241 ACPFNKAGQHPSQHLIGLRKAVYRTLRANFQAARLATLYMLKNYPLNSESDNVTNYICVV 300 Query: 301 PFKELGLGLSEEQISEEEAHNFTDGFSLPALKVLFQLWVAQSSEFFRRLALLLSTANSPP 360 PFKELGLGLSEEQISEEEAHNFTDGFSLPALKVLFQLWVAQSSEFFRRLALLLSTANSPP Sbjct: 301 PFKELGLGLSEEQISEEEAHNFTDGFSLPALKVLFQLWVAQSSEFFRRLALLLSTANSPP 360 Query: 361 GPLLTPALLPHRILSDVTQGLPHAHSACLEELKRSYEFYRYFETQHQSVPQCLSKTQQKS 420 GPLLTPALLPHRILSDVTQGLPHAHSACLEELKRSYEFYRYFETQHQSVPQCLSKTQQKS Sbjct: 361 GPLLTPALLPHRILSDVTQGLPHAHSACLEELKRSYEFYRYFETQHQSVPQCLSKTQQKS 420 Query: 421 RELNNVHTAVRSLQLHLKALLNEVIILEDELEKLVCTKETQELVSEAYPILEQKLKLIQP 480 RELNNVHTAVRSLQLHLKALLNEVIILEDELEKLVCTKETQELVSEAYPILEQKLKLIQP Sbjct: 421 RELNNVHTAVRSLQLHLKALLNEVIILEDELEKLVCTKETQELVSEAYPILEQKLKLIQP 480 Query: 481 HVQASNNCWEEAISQVDKLLRRNTDKKGKPEIACENPHCTVVPLKQPTLHIADKDPIPEE 540 HVQASNNCWEEAISQVDKLLRRNTDKKGKPEIACENPHCTVVPLKQPTLHIADKDPIPEE Sbjct: 481 HVQASNNCWEEAISQVDKLLRRNTDKKGKPEIACENPHCTVVPLKQPTLHIADKDPIPEE 540 Query: 541 QELEAYVDDIDIDSDFRKDDFYYLSQEDKERQKREHEESKRVLQELKSVLGFKASEAERQ 600 QELEAYVDDIDIDSDFRKDDFYYLSQEDKERQKREHEESKRVLQELKSVLGFKASEAERQ Sbjct: 541 QELEAYVDDIDIDSDFRKDDFYYLSQEDKERQKREHEESKRVLQELKSVLGFKASEAERQ 600 Query: 601 KWKQLLFSDHAVLKSLSPVDPVEPISNSEPSMNSDMGKVSKNDTEEESNKSATTDNEISR 660 KWKQLLFSDHAVLKSLSPVDPVEPISNSEPSMNSDMGKVSKNDTEEESNKSATTDNEISR Sbjct: 601 KWKQLLFSDHAVLKSLSPVDPVEPISNSEPSMNSDMGKVSKNDTEEESNKSATTDNEISR 660 Query: 661 TEYLCENSLEGKNKDNSSNEVFPQGAEERMCYQCESEDEPQADGSGLTTAPPTPRDSLQP 720 TEYLCENSLEGKNKDNSSNEVFPQGAEERMCYQCESEDEPQADGSGLTTAPPTPRDSLQP Sbjct: 661 TEYLCENSLEGKNKDNSSNEVFPQGAEERMCYQCESEDEPQADGSGLTTAPPTPRDSLQP 720 Query: 721 SIKQRLARLQLSPDFTFTAGLAAEVAARSLSFTTMQEQTFGGEEEEQIIEENKNEIEEK 779 SIKQRLARLQLSPDFTFTAGLAAEVAARSLSFTTMQEQTFGGEEEEQIIEENKNEIEEK Sbjct: 721 SIKQRLARLQLSPDFTFTAGLAAEVAARSLSFTTMQEQTFGGEEEEQIIEENKNEIEEK 779 >gi|122937396 coiled-coil domain containing 150 [Homo sapiens] Length = 1101 Score = 45.8 bits (107), Expect = 2e-04 Identities = 41/193 (21%), Positives = 85/193 (44%), Gaps = 21/193 (10%) Query: 417 QQKSRELNNVHTAVRSLQLHLKALLNEVIILEDELEKLVCTKETQELVSEAYPILEQKLK 476 ++ S++L +H V +L+ L+A+ E +DE+++L T + + I+E++LK Sbjct: 144 EEHSKDLKLLHLEVMNLRQQLRAVKEEEDKAQDEVQRLTATLKIASQTKKNAAIIEEELK 203 Query: 477 LIQPHVQASNNCWEEAISQVDKLLRRNTDKKGKPEIACENPHCTVVPLKQPTLHIADKDP 536 + + ++Q +K LR + +K + + V +++ +HI ++ Sbjct: 204 TTKRKMNLKIQELRRQLAQ-EKYLRESLEKSASAMLLKIQEMGSTVEVERKQVHILQQNC 262 Query: 537 I-----------------PEEQELEAYVDDIDIDSDFRKDDFYYLSQEDKERQ---KREH 576 I +++ELE + D R D L +E+K Q +EH Sbjct: 263 IALRDSIQSAQELLAQEQKKKEELEIATSQLKSDLTSRDDLISKLVEENKNLQISFNKEH 322 Query: 577 EESKRVLQELKSV 589 EE+ + E+ S+ Sbjct: 323 EENAYLRSEIMSL 335 >gi|51243032 oxysterol-binding protein-like protein 8 isoform b [Homo sapiens] Length = 847 Score = 43.1 bits (100), Expect = 0.001 Identities = 47/199 (23%), Positives = 87/199 (43%), Gaps = 31/199 (15%) Query: 462 ELVSEAYPILEQKLKLIQPHVQASNNCWEEAIS---QVDKLLRRNTDKKGKPE---IACE 515 E V L +I+ ++ CW +A+ + LL+R ++GK ++ + Sbjct: 187 EAVGSITQPLPSSYLIIRATSESDGRCWMDALELALKCSSLLKRTMIREGKEHDLSVSSD 246 Query: 516 NPHCTVVPL-KQPTLHIADKDPIPEEQELEAYVDDIDIDSDFRKDDFYYLSQEDKERQKR 574 + H T L + LH D + +D +I+ KD Y + DKE + Sbjct: 247 STHVTFYGLLRANNLHSGDNFQL----------NDSEIERQHFKDQDMYSDKSDKEND-Q 295 Query: 575 EHEESKRVLQELKSVLGFKASEAERQKWKQLLFSDHAVLKSLSPVDPVEPISNSEPSMN- 633 EH+ES V+G K+ E++ ++ D + ++ PV+P++ + +E S Sbjct: 296 EHDESD------NEVMG-KSEESDTDTSER---QDDSYIEP-EPVEPLKETTYTEQSHEE 344 Query: 634 -SDMGKVSKNDTEEESNKS 651 + G+ S+ +T E NKS Sbjct: 345 LGEAGEASQTETVSEENKS 363 >gi|18079218 oxysterol-binding protein-like protein 8 isoform a [Homo sapiens] Length = 889 Score = 43.1 bits (100), Expect = 0.001 Identities = 47/199 (23%), Positives = 87/199 (43%), Gaps = 31/199 (15%) Query: 462 ELVSEAYPILEQKLKLIQPHVQASNNCWEEAIS---QVDKLLRRNTDKKGKPE---IACE 515 E V L +I+ ++ CW +A+ + LL+R ++GK ++ + Sbjct: 229 EAVGSITQPLPSSYLIIRATSESDGRCWMDALELALKCSSLLKRTMIREGKEHDLSVSSD 288 Query: 516 NPHCTVVPL-KQPTLHIADKDPIPEEQELEAYVDDIDIDSDFRKDDFYYLSQEDKERQKR 574 + H T L + LH D + +D +I+ KD Y + DKE + Sbjct: 289 STHVTFYGLLRANNLHSGDNFQL----------NDSEIERQHFKDQDMYSDKSDKEND-Q 337 Query: 575 EHEESKRVLQELKSVLGFKASEAERQKWKQLLFSDHAVLKSLSPVDPVEPISNSEPSMN- 633 EH+ES V+G K+ E++ ++ D + ++ PV+P++ + +E S Sbjct: 338 EHDESD------NEVMG-KSEESDTDTSER---QDDSYIEP-EPVEPLKETTYTEQSHEE 386 Query: 634 -SDMGKVSKNDTEEESNKS 651 + G+ S+ +T E NKS Sbjct: 387 LGEAGEASQTETVSEENKS 405 >gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] Length = 1411 Score = 42.4 bits (98), Expect = 0.002 Identities = 81/413 (19%), Positives = 165/413 (39%), Gaps = 56/413 (13%) Query: 404 TQHQSVPQCLSKTQQKSRE----LNNVHTAVRSLQLHLKALLNEVIILEDELEKLVC-TK 458 T + V Q K + +S N+H V+ + HL+A + V+ LE + +L Sbjct: 572 TLQEQVTQLTEKLKNQSESHKQAQENLHDQVQEQKAHLRAAQDRVLSLETSVNELNSQLN 631 Query: 459 ETQELVSEAYPILEQKLKL--------------IQPHVQASNNCWEEAISQVDKL---LR 501 E++E VS+ ++ K +L +Q H+ + N ++ +++K+ L Sbjct: 632 ESKEKVSQLDIQIKAKTELLLSAEAAKTAQRADLQNHLDTAQNALQDKQQELNKITTQLD 691 Query: 502 RNTDKKGKPEIACENPHCTVVPLKQPTLHIADKDPIPEEQ--ELEAYVDDIDIDSDFRKD 559 + T K + C + K+ L + K E Q +LEA ++ + Sbjct: 692 QVTAKLQDKQEHCSQLESHLKEYKEKYLSLEQKTEELEGQIKKLEADSLEVKASKEQALQ 751 Query: 560 DFYYLSQEDKERQKREHEESKRVLQELKSVLGF-----KASEA---------ERQKWKQL 605 D Q + + + R E SK++ E + V K SEA ++++ KQ+ Sbjct: 752 DLQQQRQLNTDLELRATELSKQLEMEKEIVSSTRLDLQKKSEALESIKQKLTKQEEEKQI 811 Query: 606 LFSDHAVLKSLSPVDPVEPISNSEPSMNSDMGKVSKNDTEEESNKSATTDNEISRTEYLC 665 L D L + + E ++N + +++ KV K + E + +T +++S+ Sbjct: 812 LKQDFETLSQETKIQH-EELNNRIQTTVTELQKV-KMEKEALMTELSTVKDKLSKVSDSL 869 Query: 666 ENSLEGKNKDNSSNEVFPQGAEERMCYQCESEDEPQADGSGLTTAPPTPRDSLQPSIKQR 725 +NS K+N + E+ C + + + + Q + + +Q+ Sbjct: 870 KNSKSEFEKENQKGKAAILDL-EKTCKELKHQLQVQMENT---------------LKEQK 913 Query: 726 LARLQLSPDFTFTAGLAAEVAARSLSFTTMQEQTFGGEEEEQIIEENKNEIEE 778 + L + + L E+ + Q E+EEQ ++ N NE+++ Sbjct: 914 ELKKSLEKEKEASHQLKLELNSMQEQLIQAQNTLKQNEKEEQQLQGNINELKQ 966 >gi|46048234 nucleolar protein 8 [Homo sapiens] Length = 1167 Score = 41.6 bits (96), Expect = 0.003 Identities = 41/201 (20%), Positives = 86/201 (42%), Gaps = 30/201 (14%) Query: 571 RQKREHEESKRVLQELKSVLGFKASEAERQKWKQLLFSDHAVLKSLSPVDP-VEPISNSE 629 +QK + K Q K V E+ ++ K + S++ S+ DP + + + Sbjct: 558 KQKPKENNLKPKFQAFKGVGCLYEKESMKKSLKDSVASNNKDQNSMKHEDPSIISMEDGS 617 Query: 630 PSMNSDMGKVS-----------------KNDT--EEESNKSATTDNEISRTEYLCENSLE 670 P +N +G+V+ K T E + K+ + + R++ LE Sbjct: 618 PYVNGSLGEVTPCQHAKKANGPNYIQPQKRQTTFESQDRKAVSPSSSEKRSKNPISRPLE 677 Query: 671 GKNKDNSSNEVFPQGAEERMCY---QCESEDEPQADGSGLTTAPPTPRDSLQPSIKQRLA 727 GK + S + G ++ C+ + E+ E ++D SGLT+ +P+ S + + Sbjct: 678 GKKSLSLSAKTHNIGFDKDSCHSTTKTEASQEERSDSSGLTSLKKSPKVSSKDT------ 731 Query: 728 RLQLSPDFTFTAGLAAEVAAR 748 ++ DF+ + +++V+A+ Sbjct: 732 -REIKTDFSLSISNSSDVSAK 751 >gi|42794779 myosin 18A isoform b [Homo sapiens] Length = 2039 Score = 40.4 bits (93), Expect = 0.006 Identities = 61/292 (20%), Positives = 122/292 (41%), Gaps = 24/292 (8%) Query: 413 LSKTQQKSRELNNVHTAVRSLQLHLKALLNEVIILEDELEKLVCTKETQELVSEAYPILE 472 L + RE+ + + + A + +E E+E L + +++A LE Sbjct: 1675 LKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDD---IAKAKTALE 1731 Query: 473 QKLKLIQPHVQASNNCWEEAISQVDKLLRRNTDKKGKPEIACENPHCTVVPLKQPTLHIA 532 ++L +Q N EE +++L+ KK K +A + + Q L A Sbjct: 1732 EQLSRLQREKNEIQNRLEEDQEDMNELM-----KKHKAAVAQASRDLAQINDLQAQLEEA 1786 Query: 533 DKDPIPEEQELEAYVDDIDIDSDFRKDDFYYLSQEDKERQKREHEESKRVLQELKSVLGF 592 +K+ +++L+A ++ +L Q ++ +E+K ++EL++ L F Sbjct: 1787 NKEKQELQEKLQALQSQVE-----------FLEQSMVDKSLVSRQEAK--IRELETRLEF 1833 Query: 593 KASEAERQKWKQLLFSDHAVLKSLSPVDPVEPISNSEPSMNSDMGKVSKNDTEEESNKSA 652 + ++ +R + ++ + K D N E N + + + DT+EE + A Sbjct: 1834 ERTQVKRLESLASRLKEN-MEKLTEERDQRIAAENREKEQNKRLQRQLR-DTKEEMGELA 1891 Query: 653 TTDNEISRTEYLCENSLEGKNKDNSSNEVFPQGAEERM-CYQCESEDEPQAD 703 + E SR ++ E LE N S + + A +R+ Q EDE ++D Sbjct: 1892 RKEAEASRKKHELEMDLESLEAANQSLQADLKLAFKRIGDLQAAIEDEMESD 1943 >gi|28416946 myosin 18A isoform a [Homo sapiens] Length = 2054 Score = 40.4 bits (93), Expect = 0.006 Identities = 61/292 (20%), Positives = 122/292 (41%), Gaps = 24/292 (8%) Query: 413 LSKTQQKSRELNNVHTAVRSLQLHLKALLNEVIILEDELEKLVCTKETQELVSEAYPILE 472 L + RE+ + + + A + +E E+E L + +++A LE Sbjct: 1675 LKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDD---IAKAKTALE 1731 Query: 473 QKLKLIQPHVQASNNCWEEAISQVDKLLRRNTDKKGKPEIACENPHCTVVPLKQPTLHIA 532 ++L +Q N EE +++L+ KK K +A + + Q L A Sbjct: 1732 EQLSRLQREKNEIQNRLEEDQEDMNELM-----KKHKAAVAQASRDLAQINDLQAQLEEA 1786 Query: 533 DKDPIPEEQELEAYVDDIDIDSDFRKDDFYYLSQEDKERQKREHEESKRVLQELKSVLGF 592 +K+ +++L+A ++ +L Q ++ +E+K ++EL++ L F Sbjct: 1787 NKEKQELQEKLQALQSQVE-----------FLEQSMVDKSLVSRQEAK--IRELETRLEF 1833 Query: 593 KASEAERQKWKQLLFSDHAVLKSLSPVDPVEPISNSEPSMNSDMGKVSKNDTEEESNKSA 652 + ++ +R + ++ + K D N E N + + + DT+EE + A Sbjct: 1834 ERTQVKRLESLASRLKEN-MEKLTEERDQRIAAENREKEQNKRLQRQLR-DTKEEMGELA 1891 Query: 653 TTDNEISRTEYLCENSLEGKNKDNSSNEVFPQGAEERM-CYQCESEDEPQAD 703 + E SR ++ E LE N S + + A +R+ Q EDE ++D Sbjct: 1892 RKEAEASRKKHELEMDLESLEAANQSLQADLKLAFKRIGDLQAAIEDEMESD 1943 >gi|60302875 shugoshin-like 1 isoform A1 [Homo sapiens] Length = 527 Score = 38.5 bits (88), Expect = 0.024 Identities = 50/193 (25%), Positives = 76/193 (39%), Gaps = 39/193 (20%) Query: 566 QEDKERQKREHEESKRVLQELKSVLGFKASEAERQKWKQLLFSDHAVLKSLSPVDPVEPI 625 Q D + +KRE E+ K ++ K + +K +++E +K + KS+S D Sbjct: 284 QRDTQERKRE-EKRKANRRKSKRMSKYKENKSENKK----TVPQKKMHKSVSSNDAYNFN 338 Query: 626 SNSEPSMNSDMGKVSKNDTEEESNKSATTDNEISRTEYLCENSLEGKNKD---------- 675 + KVS + EE+N+S E+S LCE+S G + D Sbjct: 339 LEEGVHLTPFRQKVSNDSNREENNES-----EVS----LCESSGSGDDSDDLYLPTCKYI 389 Query: 676 -----NSSNEVFPQGAEERMCYQCESEDEPQADGSGLTTAPPTPRDSLQPSIKQ------ 724 NS V A+ + Y E E E TT PP + S S+K Sbjct: 390 QNPTSNSDRPVTRPLAKRALKYTDEKETEGSKPTKTPTTTPPETQQSPHLSLKDITNVSL 449 Query: 725 ----RLARLQLSP 733 ++ RL LSP Sbjct: 450 YPVVKIRRLSLSP 462 >gi|60302870 shugoshin-like 1 isoform A2 [Homo sapiens] Length = 561 Score = 38.5 bits (88), Expect = 0.024 Identities = 50/193 (25%), Positives = 76/193 (39%), Gaps = 39/193 (20%) Query: 566 QEDKERQKREHEESKRVLQELKSVLGFKASEAERQKWKQLLFSDHAVLKSLSPVDPVEPI 625 Q D + +KRE E+ K ++ K + +K +++E +K + KS+S D Sbjct: 284 QRDTQERKRE-EKRKANRRKSKRMSKYKENKSENKK----TVPQKKMHKSVSSNDAYNFN 338 Query: 626 SNSEPSMNSDMGKVSKNDTEEESNKSATTDNEISRTEYLCENSLEGKNKD---------- 675 + KVS + EE+N+S E+S LCE+S G + D Sbjct: 339 LEEGVHLTPFRQKVSNDSNREENNES-----EVS----LCESSGSGDDSDDLYLPTCKYI 389 Query: 676 -----NSSNEVFPQGAEERMCYQCESEDEPQADGSGLTTAPPTPRDSLQPSIKQ------ 724 NS V A+ + Y E E E TT PP + S S+K Sbjct: 390 QNPTSNSDRPVTRPLAKRALKYTDEKETEGSKPTKTPTTTPPETQQSPHLSLKDITNVSL 449 Query: 725 ----RLARLQLSP 733 ++ RL LSP Sbjct: 450 YPVVKIRRLSLSP 462 >gi|149363642 coiled-coil domain containing 144A [Homo sapiens] Length = 1427 Score = 37.4 bits (85), Expect = 0.054 Identities = 56/229 (24%), Positives = 98/229 (42%), Gaps = 23/229 (10%) Query: 397 EFYRYFETQHQSVPQCLSKTQQKSRELNNVHTAVRSLQLHL----KALLNEVIILEDELE 452 E+ R + + +K + S +L+N + + SLQ+ L AL E +ILE Sbjct: 946 EWVRLHDKMKVDMSGLQAKNEILSEKLSNAESKINSLQIQLHNTRDALGRESLILERVQR 1005 Query: 453 KLVCTKETQELVSEAYPILEQKLKLIQPHVQASNNCWEEAISQV---DKLLRRNTDKKGK 509 L T+ ++ + Y I + KLK A EE +SQ+ + LLR+ D K Sbjct: 1006 DLSQTQCQKKETEQMYQIEQSKLK----KYIAKQESVEERLSQLQSENMLLRQQLDDAHK 1061 Query: 510 PEIACENPHCTVVPLKQPTLHIADKDPIPEEQELEAYVDDIDIDSDFRKDDFYYLSQEDK 569 + E T+ Q H A K+ + E E + + + D++ +L +E Sbjct: 1062 KANSQEKTSSTI----QDQFHSAAKN---LQAESEKQILSLQEKNKELMDEYNHL-KERM 1113 Query: 570 ERQKREHEESKRVLQELKSVLGFKA----SEAERQKWKQLLFSDHAVLK 614 ++ ++E K L E + + + +E E + +Q LFS A+ K Sbjct: 1114 DQCEKEKAGRKIDLTEAQETVPSRCLHLDAENEVLQLQQTLFSMKAIQK 1162 >gi|7019419 guanine nucleotide binding protein-like 2 (nucleolar) [Homo sapiens] Length = 731 Score = 36.2 bits (82), Expect = 0.12 Identities = 42/196 (21%), Positives = 86/196 (43%), Gaps = 28/196 (14%) Query: 477 LIQPHVQASNNCWEEAISQVDKLLRRNTDKKGKPEIACENPHCTVVPLKQPTLHIADKDP 536 +I+ + +++C +A +++ ++L R GK + + +VP++ L Sbjct: 505 IIKEETEENSHC--DANTEMQQILTRVRQNFGKINVVPQFSGDDLVPVEVSDL------- 555 Query: 537 IPEEQELEAYVDDIDIDSDFRKDDFYYLSQEDKERQKREHEESKRVLQELKSVLGFKASE 596 E+ELE++ D+ + + + ++DD S E +E + ++K V++ L + Sbjct: 556 ---EEELESFSDEEEEEQEQQRDDAEESSSEPEE--ENVGNDTKAVIKALDEKIAKYQKF 610 Query: 597 AERQKWKQLLFSDHAVLKSLSPVDPVEP----------ISNSEPSMNSDMGKVSKNDTEE 646 ++ K K+ FS + K LS +P + + PS K + + +E Sbjct: 611 LDKAKAKK--FSAVRISKGLSEKIFAKPEEQRKTLEEDVDDRAPSKKGKKRKAQREEEQE 668 Query: 647 ESNKS--ATTDNEISR 660 SNK+ A T E R Sbjct: 669 HSNKAPRALTSKERRR 684 >gi|29789058 WW and C2 domain containing 1 isoform 3 [Homo sapiens] Length = 1113 Score = 36.2 bits (82), Expect = 0.12 Identities = 43/169 (25%), Positives = 72/169 (42%), Gaps = 30/169 (17%) Query: 454 LVCTKETQELVSEAYPILEQKLKLIQPHVQASNNCWEEAI-SQVDKLLRRNTDKKGKPEI 512 LV +E E Y + +Q+L+L Q Q + WE + SQV + ++ K PEI Sbjct: 100 LVVAQEALSAQKEIYQVKQQRLELAQQEYQQLHAVWEHKLGSQVSLVSGSSSSSKYDPEI 159 Query: 513 ---ACENPHCTVVPLKQPTLHIADKDPIPEEQELEAYVDDIDIDSDFRKDDFYYLSQEDK 569 V LK+ +H+ + EL+ F++ F L + DK Sbjct: 160 LKAEIATAKSRVNKLKREMVHL--------QHELQ-----------FKERGFQTLKKIDK 200 Query: 570 ERQKREH----EESKRVLQELKSVLGFKASEAERQKWKQLLFSDHAVLK 614 + + +E++ VL+E K++ K + +K KQ L A+LK Sbjct: 201 KMSDAQGSYKLDEAQAVLRETKAI---KKAITCGEKEKQDLIKSLAMLK 246 >gi|242247257 WW and C2 domain containing 1 isoform 2 [Homo sapiens] Length = 1118 Score = 36.2 bits (82), Expect = 0.12 Identities = 43/169 (25%), Positives = 72/169 (42%), Gaps = 30/169 (17%) Query: 454 LVCTKETQELVSEAYPILEQKLKLIQPHVQASNNCWEEAI-SQVDKLLRRNTDKKGKPEI 512 LV +E E Y + +Q+L+L Q Q + WE + SQV + ++ K PEI Sbjct: 100 LVVAQEALSAQKEIYQVKQQRLELAQQEYQQLHAVWEHKLGSQVSLVSGSSSSSKYDPEI 159 Query: 513 ---ACENPHCTVVPLKQPTLHIADKDPIPEEQELEAYVDDIDIDSDFRKDDFYYLSQEDK 569 V LK+ +H+ + EL+ F++ F L + DK Sbjct: 160 LKAEIATAKSRVNKLKREMVHL--------QHELQ-----------FKERGFQTLKKIDK 200 Query: 570 ERQKREH----EESKRVLQELKSVLGFKASEAERQKWKQLLFSDHAVLK 614 + + +E++ VL+E K++ K + +K KQ L A+LK Sbjct: 201 KMSDAQGSYKLDEAQAVLRETKAI---KKAITCGEKEKQDLIKSLAMLK 246 >gi|242247251 WW and C2 domain containing 1 isoform 1 [Homo sapiens] Length = 1119 Score = 36.2 bits (82), Expect = 0.12 Identities = 43/169 (25%), Positives = 72/169 (42%), Gaps = 30/169 (17%) Query: 454 LVCTKETQELVSEAYPILEQKLKLIQPHVQASNNCWEEAI-SQVDKLLRRNTDKKGKPEI 512 LV +E E Y + +Q+L+L Q Q + WE + SQV + ++ K PEI Sbjct: 100 LVVAQEALSAQKEIYQVKQQRLELAQQEYQQLHAVWEHKLGSQVSLVSGSSSSSKYDPEI 159 Query: 513 ---ACENPHCTVVPLKQPTLHIADKDPIPEEQELEAYVDDIDIDSDFRKDDFYYLSQEDK 569 V LK+ +H+ + EL+ F++ F L + DK Sbjct: 160 LKAEIATAKSRVNKLKREMVHL--------QHELQ-----------FKERGFQTLKKIDK 200 Query: 570 ERQKREH----EESKRVLQELKSVLGFKASEAERQKWKQLLFSDHAVLK 614 + + +E++ VL+E K++ K + +K KQ L A+LK Sbjct: 201 KMSDAQGSYKLDEAQAVLRETKAI---KKAITCGEKEKQDLIKSLAMLK 246 >gi|50658069 phosphodiesterase 4D interacting protein isoform 2 [Homo sapiens] Length = 969 Score = 36.2 bits (82), Expect = 0.12 Identities = 76/371 (20%), Positives = 147/371 (39%), Gaps = 54/371 (14%) Query: 368 LLPHRILSDVTQGLPHAHSACLEELKRSYEFYRYFETQHQSVPQCLSKTQQKSRELNNVH 427 LL +R SD T A+ LE+L++ + +++ + S ++K +EL + Sbjct: 456 LLQYRDNSDKTL---EANEMLLEKLRQ--RIHDKAVALERAIDEKFSALEEKEKELRQLR 510 Query: 428 TAVRSLQLHLKALLNEVIILEDELEKLVCTKETQELVSEAYPILEQKLKLIQPHVQASNN 487 AVR L+ L + + E ++ + + L E Q L+ ++ ++ + Sbjct: 511 LAVRERDHDLERLRDVLSSNEATMQSMESLLRAKGLEVEQLSTTCQNLQWLKEEMETKFS 570 Query: 488 CWE-EAISQVDKLLRRNTDKKGKPEIACENPHCTVVPLKQPTLHIADKDPIPEE--QELE 544 W+ E S + +L D+ + E C + P + I EE Q L+ Sbjct: 571 RWQKEQESIIQQLQTSLHDRNKEVEDLSATLLCKLGP---------GQSEIAEELCQRLQ 621 Query: 545 AYVDDIDIDSDFRKDDFYYLSQEDKERQKREHE-ESKRVLQELKSVLGFKASEAERQKWK 603 RK+ D+ +Q EHE E + +LQ + + + S+A +K Sbjct: 622 ------------RKERMLQDLLSDRNKQVLEHEMEIQGLLQSVST--REQESQAAAEKLV 667 Query: 604 QLLFSDHAVLKSL-------SPVDPVEPISNSEPSM--------NSDMGKVSKNDTEEES 648 Q L ++ L++L + PISN + + +D G + ++ + Sbjct: 668 QALMERNSELQALRQYLGGRDSLMSQAPISNQQAEVTPTGCLGKQTDQGSMQIPSRDDST 727 Query: 649 NKSATTDNEISRTEYLCENSLEGKNKDNSSNEVFPQGAEERMCYQCESEDEPQADGSGLT 708 + +A D I R+ +++ G K+ S+ A+E + + E E Q + S L Sbjct: 728 SLTAKEDVSIPRSTLGDLDTVAGLEKELSN-------AKEELELMAKKERESQMELSALQ 780 Query: 709 TAPPTPRDSLQ 719 + + LQ Sbjct: 781 SMMAVQEEELQ 791 >gi|50658071 phosphodiesterase 4D interacting protein isoform 5 [Homo sapiens] Length = 1132 Score = 36.2 bits (82), Expect = 0.12 Identities = 76/371 (20%), Positives = 147/371 (39%), Gaps = 54/371 (14%) Query: 368 LLPHRILSDVTQGLPHAHSACLEELKRSYEFYRYFETQHQSVPQCLSKTQQKSRELNNVH 427 LL +R SD T A+ LE+L++ + +++ + S ++K +EL + Sbjct: 619 LLQYRDNSDKTL---EANEMLLEKLRQ--RIHDKAVALERAIDEKFSALEEKEKELRQLR 673 Query: 428 TAVRSLQLHLKALLNEVIILEDELEKLVCTKETQELVSEAYPILEQKLKLIQPHVQASNN 487 AVR L+ L + + E ++ + + L E Q L+ ++ ++ + Sbjct: 674 LAVRERDHDLERLRDVLSSNEATMQSMESLLRAKGLEVEQLSTTCQNLQWLKEEMETKFS 733 Query: 488 CWE-EAISQVDKLLRRNTDKKGKPEIACENPHCTVVPLKQPTLHIADKDPIPEE--QELE 544 W+ E S + +L D+ + E C + P + I EE Q L+ Sbjct: 734 RWQKEQESIIQQLQTSLHDRNKEVEDLSATLLCKLGP---------GQSEIAEELCQRLQ 784 Query: 545 AYVDDIDIDSDFRKDDFYYLSQEDKERQKREHE-ESKRVLQELKSVLGFKASEAERQKWK 603 RK+ D+ +Q EHE E + +LQ + + + S+A +K Sbjct: 785 ------------RKERMLQDLLSDRNKQVLEHEMEIQGLLQSVST--REQESQAAAEKLV 830 Query: 604 QLLFSDHAVLKSL-------SPVDPVEPISNSEPSM--------NSDMGKVSKNDTEEES 648 Q L ++ L++L + PISN + + +D G + ++ + Sbjct: 831 QALMERNSELQALRQYLGGRDSLMSQAPISNQQAEVTPTGCLGKQTDQGSMQIPSRDDST 890 Query: 649 NKSATTDNEISRTEYLCENSLEGKNKDNSSNEVFPQGAEERMCYQCESEDEPQADGSGLT 708 + +A D I R+ +++ G K+ S+ A+E + + E E Q + S L Sbjct: 891 SLTAKEDVSIPRSTLGDLDTVAGLEKELSN-------AKEELELMAKKERESQMELSALQ 943 Query: 709 TAPPTPRDSLQ 719 + + LQ Sbjct: 944 SMMAVQEEELQ 954 >gi|157311604 phosphodiesterase 4D interacting protein isoform 1 [Homo sapiens] Length = 2346 Score = 36.2 bits (82), Expect = 0.12 Identities = 76/371 (20%), Positives = 147/371 (39%), Gaps = 54/371 (14%) Query: 368 LLPHRILSDVTQGLPHAHSACLEELKRSYEFYRYFETQHQSVPQCLSKTQQKSRELNNVH 427 LL +R SD T A+ LE+L++ + +++ + S ++K +EL + Sbjct: 456 LLQYRDNSDKTL---EANEMLLEKLRQ--RIHDKAVALERAIDEKFSALEEKEKELRQLR 510 Query: 428 TAVRSLQLHLKALLNEVIILEDELEKLVCTKETQELVSEAYPILEQKLKLIQPHVQASNN 487 AVR L+ L + + E ++ + + L E Q L+ ++ ++ + Sbjct: 511 LAVRERDHDLERLRDVLSSNEATMQSMESLLRAKGLEVEQLSTTCQNLQWLKEEMETKFS 570 Query: 488 CWE-EAISQVDKLLRRNTDKKGKPEIACENPHCTVVPLKQPTLHIADKDPIPEE--QELE 544 W+ E S + +L D+ + E C + P + I EE Q L+ Sbjct: 571 RWQKEQESIIQQLQTSLHDRNKEVEDLSATLLCKLGP---------GQSEIAEELCQRLQ 621 Query: 545 AYVDDIDIDSDFRKDDFYYLSQEDKERQKREHE-ESKRVLQELKSVLGFKASEAERQKWK 603 RK+ D+ +Q EHE E + +LQ + + + S+A +K Sbjct: 622 ------------RKERMLQDLLSDRNKQVLEHEMEIQGLLQSVST--REQESQAAAEKLV 667 Query: 604 QLLFSDHAVLKSL-------SPVDPVEPISNSEPSM--------NSDMGKVSKNDTEEES 648 Q L ++ L++L + PISN + + +D G + ++ + Sbjct: 668 QALMERNSELQALRQYLGGRDSLMSQAPISNQQAEVTPTGCLGKQTDQGSMQIPSRDDST 727 Query: 649 NKSATTDNEISRTEYLCENSLEGKNKDNSSNEVFPQGAEERMCYQCESEDEPQADGSGLT 708 + +A D I R+ +++ G K+ S+ A+E + + E E Q + S L Sbjct: 728 SLTAKEDVSIPRSTLGDLDTVAGLEKELSN-------AKEELELMAKKERESQMELSALQ 780 Query: 709 TAPPTPRDSLQ 719 + + LQ Sbjct: 781 SMMAVQEEELQ 791 >gi|4502443 dystonin isoform 1e precursor [Homo sapiens] Length = 2649 Score = 36.2 bits (82), Expect = 0.12 Identities = 38/208 (18%), Positives = 86/208 (41%), Gaps = 37/208 (17%) Query: 389 LEELKRSYEFYRYFETQHQSVPQCLSKTQQKSRELNNVHTAVRSLQLHLKALLNEVIILE 448 L+++KR+Y+ + +S+ K Q++ + H HL + ++ E Sbjct: 1462 LKKIKRNYQL------ELESLNHEKGKLQREVDRITRAHAVAEKNIQHLNSQIHSFRD-E 1514 Query: 449 DELEKL-VCTKETQELVSEAYPILEQ-------------KLKLIQPHVQASNNCWEEAIS 494 ELE+L +C +++ L + EQ K++ + ++ SN C E Sbjct: 1515 KELERLQICQRKSDHLKEQFEKSHEQLLQNIKAEKENNDKIQRLNEELEKSNECAEMLKQ 1574 Query: 495 QVDKLLRRNTDKKGKPEIACENPHCTVVPLKQPTLHIADKDPIPEEQELEAYVDDIDIDS 554 +V++L R+N + K L + ++ + E+Q ++ + + I + Sbjct: 1575 KVEELTRQNNETK----------------LMMQRIQAESENIVLEKQTIQQRCEALKIQA 1618 Query: 555 DFRKDDFYYLSQEDKERQKREHEESKRV 582 D KD ++ ++ K E + +++ Sbjct: 1619 DGFKDQLRSTNEHLHKQTKTEQDFQRKI 1646 >gi|12711674 UPF3 regulator of nonsense transcripts homolog B isoform 2 [Homo sapiens] Length = 470 Score = 36.2 bits (82), Expect = 0.12 Identities = 37/164 (22%), Positives = 66/164 (40%), Gaps = 12/164 (7%) Query: 472 EQKLKLIQPHVQASNNCWEEAISQVDKLLRRNTDKKGKPEIACENPHCTVVPLKQPTLHI 531 E K+KL++ + E+ + + +K + DK+ + CT+ L Sbjct: 265 EPKIKLLKKPEKGD----EKELDKREKA--KKLDKENLSDERASGQSCTLPKRSDSEL-- 316 Query: 532 ADKDPIPEEQELEAYVDDIDIDSDFRKDDFYYLSQEDKERQKREHEESKRVLQELKSVLG 591 KD P+ E E+ D + + ++ +D L ++ER KR+ EE +R + + Sbjct: 317 --KDEKPKRPEDESGRDYREREREYERDQERIL--RERERLKRQEEERRRQKERYEKEKT 372 Query: 592 FKASEAERQKWKQLLFSDHAVLKSLSPVDPVEPISNSEPSMNSD 635 FK E E +K K L +S + E E + D Sbjct: 373 FKRKEEEMKKEKDTLRDKGKKAESTESIGSSEKTEKKEEVVKRD 416 >gi|237858619 polyamine modulated factor 1 binding protein 1 isoform a [Homo sapiens] Length = 1007 Score = 35.8 bits (81), Expect = 0.16 Identities = 46/223 (20%), Positives = 91/223 (40%), Gaps = 16/223 (7%) Query: 373 ILSDVTQGLPHAHSACLEELKRSYEFYRYFETQHQSVPQCLSKTQQKSRELNNVHTAVRS 432 I + L +AC ++L ++ E + ++ +S+ Q L++TQ+K +L A Sbjct: 726 ITKEAYDALSRKSAACQDDLTQALEKLNHVTSETKSLQQSLTQTQEKKAQLEEEIIAYEE 785 Query: 433 LQLHLKALLNEV--IILEDELEKLVCTKETQELVSEAYPILEQ---KLKLIQPHVQASNN 487 L L ++ E ELE K+ +E+ + +Q LK++ + Sbjct: 786 RMKKLNTELRKLRGFHQESELEVHAFDKKLEEMSCQVLQWQKQHQNDLKMLAAKEEQLRE 845 Query: 488 CWEEAISQVDKLLRRNTDKKGKPEIACENPHC--------TVVPLKQ--PTLHIADKDPI 537 EE + + LL + + P+ + C + L+Q +A++ Sbjct: 846 FQEEMAALKENLLEDDKEPCCLPQWSVPKDTCRLYRGNDQIMTNLEQWAKQQKVANEKLG 905 Query: 538 PEEQELEAYVDDIDIDSDFRKDDFYYLSQEDKERQKREHEESK 580 + +E Y+ + + D +L QE+K + K+E EE K Sbjct: 906 NQLREQVKYIAKLSGEKDHLHSVMVHLQQENK-KLKKEIEEKK 947 >gi|154277116 spectrin repeat containing, nuclear envelope 1 isoform 1 [Homo sapiens] Length = 8797 Score = 35.8 bits (81), Expect = 0.16 Identities = 69/322 (21%), Positives = 124/322 (38%), Gaps = 53/322 (16%) Query: 361 GPLLTPALLPHRILSDVTQGLPHAHSACLEELKRSYEFYRYFETQHQS-VPQCLSKTQQK 419 G L+ P LL L +TQ L H H A +EE+ + + + + + QC Q K Sbjct: 3943 GRLVAPDLLETSSLETITQQLAH-HKAMMEEIAGFEDRLNNLQMKGDTLIGQCADHLQAK 4001 Query: 420 SRELNNVHTAVRSLQLHLKALLNEVI----ILEDELEKLVCTKET----QELVSEAYPIL 471 ++ NVH ++ + A+ + LE EL+K V ++T Q +S P L Sbjct: 4002 LKQ--NVHAHLQGTKDSYSAICSTAQRMYQSLEHELQKHVSRQDTLQQCQAWLSAVQPDL 4059 Query: 472 EQKLKLIQPHVQASNNCWEEAISQVDKLLRRNTDKKGKPEIACENPHCTVVPLKQPTLHI 531 E QP + + EAI QV + ++ C + +K I Sbjct: 4060 EPSP---QPPLSRA-----EAIKQVKHFRALQEQARTYLDLLCSMCDLSNASVKTTAKDI 4111 Query: 532 ADKDPIPEEQELEAY--VDDIDIDSDFRKDDFYYLSQEDKERQ--KREHEESK-RVLQEL 586 + E++ ++A + + + + YL D++ Q KR H E + + Q + Sbjct: 4112 QQTEQTIEQKLVQAQNLTQGWEEIKHLKSELWIYLQDADQQLQNMKRRHSELELNIAQNM 4171 Query: 587 KSVLGFKASEAERQKWKQLLFSDHAVLKSLSPVDPVEPISNSEPSMNSDMGKVSKNDTEE 646 S + D V+ + + + S+N+ + KV+K +E Sbjct: 4172 VSQVK----------------------------DFVKKLQSKQASVNTIIEKVNKLTKKE 4203 Query: 647 ESNKSATTDNEISRTEYLCENS 668 ES + ++ + LC S Sbjct: 4204 ESPEHKEINHLNDQWLDLCRQS 4225 Score = 33.1 bits (74), Expect = 1.0 Identities = 50/235 (21%), Positives = 94/235 (40%), Gaps = 22/235 (9%) Query: 389 LEELKRSYEFY-RYFETQHQSVPQCLSKTQ----QKSRELNNVHTAVRSLQLHLKALLNE 443 LEE K+ F + +E + + L K + + S+ L + H + + Q+ K L N Sbjct: 7661 LEEQKKKLAFLLKDWEKCEKGIADSLEKLRTFKKKLSQSLPDHHEELHAEQMRCKELENA 7720 Query: 444 VIILEDELEKLVCTKETQE--LVSEAYPILEQKLKLIQPHVQASNNCWEEAISQVDKLLR 501 V D+L +L K+T + ++ IL ++++L+Q WEE Q+ + Sbjct: 7721 VGSWTDDLTQLSLLKDTLSAYISADDISILNERVELLQRQ-------WEELCHQLSLRRQ 7773 Query: 502 RNTDKKGKPEIACENPHCTVVPLKQPTLHIADKDPIPEEQELEAYVDDIDIDSDFRKDDF 561 + ++ + + E L Q ++ I E+ +E D + +++ Sbjct: 7774 QIGERLNEWAVFSEKNKELCEWLTQMESKVSQNGDILIEEMIEKLKKDYQEEIAIAQENK 7833 Query: 562 YYLSQEDKERQKREHEESKRVLQELKSVLGFKASEAERQKWKQLLFSDHAVLKSL 616 L Q + K HE E++ LG +W+ LL A +K L Sbjct: 7834 IQLQQMGERLAKASHESK---ASEIEYKLG-----KVNDRWQHLLDLIAARVKKL 7880 >gi|9257180 adducin 2 isoform c [Homo sapiens] Length = 420 Score = 35.8 bits (81), Expect = 0.16 Identities = 42/198 (21%), Positives = 80/198 (40%), Gaps = 19/198 (9%) Query: 534 KDPIPEEQELEAYVDDIDIDSDFR-KDDFYYLSQEDKERQKREHEESKRVLQELKSVLGF 592 + P E Q + +D DS+ + F L+ ++ E K+E E K L G Sbjct: 223 RSPSTESQLMSKGDEDTKDDSEETVPNPFSQLTDQELEEYKKEVERKKLELD------GE 276 Query: 593 KASEAERQKWKQLLFSDHAVLKSLSPVDPVEPISNSEPSMNSDMGKVSKNDTEEESNKSA 652 K + E A SPV + ++ + S + + + E++K+A Sbjct: 277 KETAPEEP-------GSPAKSAPASPVQSPAKEAETKSPLVSPSKSLEEGTKKTETSKAA 329 Query: 653 TTDNEISRTEYLCENSLEGKNKDNSSNEVFPQGAEERMCYQCESEDEPQADGSGLTTAPP 712 TT+ E ++ E + N G+ ++ ++ E+ +G + D + +T+ P Sbjct: 330 TTEPETTQPEGVVVN---GREEEQTAEEILSKGLSQMTTSADTDVDTSKDKTESVTSGPM 386 Query: 713 TPR--DSLQPSIKQRLAR 728 +P S PS K++ R Sbjct: 387 SPEGSPSKSPSKKKKKFR 404 >gi|9257192 adducin 2 isoform a [Homo sapiens] Length = 726 Score = 35.8 bits (81), Expect = 0.16 Identities = 42/198 (21%), Positives = 80/198 (40%), Gaps = 19/198 (9%) Query: 534 KDPIPEEQELEAYVDDIDIDSDFR-KDDFYYLSQEDKERQKREHEESKRVLQELKSVLGF 592 + P E Q + +D DS+ + F L+ ++ E K+E E K L G Sbjct: 529 RSPSTESQLMSKGDEDTKDDSEETVPNPFSQLTDQELEEYKKEVERKKLELD------GE 582 Query: 593 KASEAERQKWKQLLFSDHAVLKSLSPVDPVEPISNSEPSMNSDMGKVSKNDTEEESNKSA 652 K + E A SPV + ++ + S + + + E++K+A Sbjct: 583 KETAPEEP-------GSPAKSAPASPVQSPAKEAETKSPLVSPSKSLEEGTKKTETSKAA 635 Query: 653 TTDNEISRTEYLCENSLEGKNKDNSSNEVFPQGAEERMCYQCESEDEPQADGSGLTTAPP 712 TT+ E ++ E + N G+ ++ ++ E+ +G + D + +T+ P Sbjct: 636 TTEPETTQPEGVVVN---GREEEQTAEEILSKGLSQMTTSADTDVDTSKDKTESVTSGPM 692 Query: 713 TPR--DSLQPSIKQRLAR 728 +P S PS K++ R Sbjct: 693 SPEGSPSKSPSKKKKKFR 710 >gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens] Length = 770 Score = 35.4 bits (80), Expect = 0.20 Identities = 29/122 (23%), Positives = 54/122 (44%), Gaps = 9/122 (7%) Query: 599 RQKWKQLLFSDHAVLKSLSPVDPVEPISNSEPSMNSDMGKVSKNDTEEESNK----SATT 654 R+ K+ + +L L + E ++S S +++ G S+ + EEE + S + Sbjct: 237 RKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSE 296 Query: 655 DNEISRTEYLCENSLEGKNKDNSSNEVFPQGAEERMCYQCESEDEPQADGSGLTTAPPTP 714 ++E E E G N + +S + + +EE M SEDE + + + L P + Sbjct: 297 ESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEM-----SEDEERENENHLLVVPESR 351 Query: 715 RD 716 D Sbjct: 352 FD 353 >gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens] Length = 780 Score = 35.4 bits (80), Expect = 0.20 Identities = 29/122 (23%), Positives = 54/122 (44%), Gaps = 9/122 (7%) Query: 599 RQKWKQLLFSDHAVLKSLSPVDPVEPISNSEPSMNSDMGKVSKNDTEEESNK----SATT 654 R+ K+ + +L L + E ++S S +++ G S+ + EEE + S + Sbjct: 247 RKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSE 306 Query: 655 DNEISRTEYLCENSLEGKNKDNSSNEVFPQGAEERMCYQCESEDEPQADGSGLTTAPPTP 714 ++E E E G N + +S + + +EE M SEDE + + + L P + Sbjct: 307 ESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEM-----SEDEERENENHLLVVPESR 361 Query: 715 RD 716 D Sbjct: 362 FD 363 >gi|18375528 UPF3 regulator of nonsense transcripts homolog B isoform 1 [Homo sapiens] Length = 483 Score = 35.4 bits (80), Expect = 0.20 Identities = 31/134 (23%), Positives = 52/134 (38%), Gaps = 6/134 (4%) Query: 502 RNTDKKGKPEIACENPHCTVVPLKQPTLHIADKDPIPEEQELEAYVDDIDIDSDFRKDDF 561 + DK+ + CT+ L KD P+ E E+ D + + ++ +D Sbjct: 302 KKLDKENLSDERASGQSCTLPKRSDSEL----KDEKPKRPEDESGRDYREREREYERDQE 357 Query: 562 YYLSQEDKERQKREHEESKRVLQELKSVLGFKASEAERQKWKQLLFSDHAVLKSLSPVDP 621 L ++ER KR+ EE +R + + FK E E +K K L +S + Sbjct: 358 RIL--RERERLKRQEEERRRQKERYEKEKTFKRKEEEMKKEKDTLRDKGKKAESTESIGS 415 Query: 622 VEPISNSEPSMNSD 635 E E + D Sbjct: 416 SEKTEKKEEVVKRD 429 >gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform 9 [Homo sapiens] Length = 771 Score = 35.4 bits (80), Expect = 0.20 Identities = 29/122 (23%), Positives = 54/122 (44%), Gaps = 9/122 (7%) Query: 599 RQKWKQLLFSDHAVLKSLSPVDPVEPISNSEPSMNSDMGKVSKNDTEEESNK----SATT 654 R+ K+ + +L L + E ++S S +++ G S+ + EEE + S + Sbjct: 238 RKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSE 297 Query: 655 DNEISRTEYLCENSLEGKNKDNSSNEVFPQGAEERMCYQCESEDEPQADGSGLTTAPPTP 714 ++E E E G N + +S + + +EE M SEDE + + + L P + Sbjct: 298 ESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEM-----SEDEERENENHLLVVPESR 352 Query: 715 RD 716 D Sbjct: 353 FD 354 >gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isoform 8 [Homo sapiens] Length = 780 Score = 35.4 bits (80), Expect = 0.20 Identities = 29/122 (23%), Positives = 54/122 (44%), Gaps = 9/122 (7%) Query: 599 RQKWKQLLFSDHAVLKSLSPVDPVEPISNSEPSMNSDMGKVSKNDTEEESNK----SATT 654 R+ K+ + +L L + E ++S S +++ G S+ + EEE + S + Sbjct: 247 RKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSE 306 Query: 655 DNEISRTEYLCENSLEGKNKDNSSNEVFPQGAEERMCYQCESEDEPQADGSGLTTAPPTP 714 ++E E E G N + +S + + +EE M SEDE + + + L P + Sbjct: 307 ESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEM-----SEDEERENENHLLVVPESR 361 Query: 715 RD 716 D Sbjct: 362 FD 363 >gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isoform 5 [Homo sapiens] Length = 748 Score = 35.4 bits (80), Expect = 0.20 Identities = 29/122 (23%), Positives = 54/122 (44%), Gaps = 9/122 (7%) Query: 599 RQKWKQLLFSDHAVLKSLSPVDPVEPISNSEPSMNSDMGKVSKNDTEEESNK----SATT 654 R+ K+ + +L L + E ++S S +++ G S+ + EEE + S + Sbjct: 215 RKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSE 274 Query: 655 DNEISRTEYLCENSLEGKNKDNSSNEVFPQGAEERMCYQCESEDEPQADGSGLTTAPPTP 714 ++E E E G N + +S + + +EE M SEDE + + + L P + Sbjct: 275 ESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEM-----SEDEERENENHLLVVPESR 329 Query: 715 RD 716 D Sbjct: 330 FD 331 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.315 0.131 0.378 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 30,759,318 Number of Sequences: 37866 Number of extensions: 1452320 Number of successful extensions: 6816 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 12 Number of HSP's successfully gapped in prelim test: 187 Number of HSP's that attempted gapping in prelim test: 6515 Number of HSP's gapped (non-prelim): 525 length of query: 779 length of database: 18,247,518 effective HSP length: 110 effective length of query: 669 effective length of database: 14,082,258 effective search space: 9421030602 effective search space used: 9421030602 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.