Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 15451921
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|15451921 platelet derived growth factor D isoform 2
precursor [Homo sapiens]
(364 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|15451921 platelet derived growth factor D isoform 2 precursor... 760 0.0
gi|13376808 platelet derived growth factor D isoform 1 precursor... 753 0.0
gi|9994187 platelet-derived growth factor C precursor [Homo sapi... 280 1e-75
gi|5902808 bone morphogenetic protein 1 isoform 2 precursor [Hom... 76 5e-14
gi|4502421 bone morphogenetic protein 1 isoform 1 precursor [Hom... 75 1e-13
gi|5453579 bone morphogenetic protein 1 isoform 3 precursor [Hom... 75 1e-13
gi|6912724 tolloid-like 2 [Homo sapiens] 74 2e-13
gi|22547221 tolloid-like 1 [Homo sapiens] 69 9e-12
gi|66864913 neuropilin 1 isoform c [Homo sapiens] 65 1e-10
gi|66912178 neuropilin 1 isoform b [Homo sapiens] 65 1e-10
gi|182508169 neuropilin 1 isoform a [Homo sapiens] 65 1e-10
gi|126091152 cubilin [Homo sapiens] 64 2e-10
gi|41872572 neuropilin 2 isoform 3 precursor [Homo sapiens] 63 4e-10
gi|41872567 neuropilin 2 isoform 5 precursor [Homo sapiens] 63 4e-10
gi|41872562 neuropilin 2 isoform 1 precursor [Homo sapiens] 63 4e-10
gi|41872557 neuropilin 2 isoform 6 precursor [Homo sapiens] 63 4e-10
gi|41872544 neuropilin 2 isoform 4 precursor [Homo sapiens] 63 4e-10
gi|41872533 neuropilin 2 isoform 2 precursor [Homo sapiens] 63 4e-10
gi|38045890 CUB and Sushi multiple domains 3 isoform 2 [Homo sap... 62 8e-10
gi|205277354 CUB and Sushi multiple domains 3 isoform 3 [Homo sa... 62 8e-10
gi|38045888 CUB and Sushi multiple domains 3 isoform 1 [Homo sap... 62 8e-10
gi|24041026 neuropilin- and tolloid-like protein 2 precursor [Ho... 61 2e-09
gi|21264363 mannan-binding lectin serine protease 2 isoform 1 pr... 58 2e-08
gi|13899255 membrane frizzled-related protein [Homo sapiens] 58 2e-08
gi|92110053 CUB and Sushi multiple domains 2 [Homo sapiens] 54 2e-07
gi|157502199 CUB and Sushi multiple domains 1 [Homo sapiens] 54 3e-07
gi|72384339 CUB domain containing protein 2 [Homo sapiens] 53 4e-07
gi|73623026 mannan-binding lectin serine protease 1 isoform 3 [H... 52 8e-07
gi|21264359 mannan-binding lectin serine protease 1 isoform 2 pr... 52 8e-07
gi|21264357 mannan-binding lectin serine protease 1 isoform 1 pr... 52 8e-07
>gi|15451921 platelet derived growth factor D isoform 2 precursor
[Homo sapiens]
Length = 364
Score = 760 bits (1962), Expect = 0.0
Identities = 364/364 (100%), Positives = 364/364 (100%)
Query: 1 MHRLIFVYTLICANFCSCRDTSATPQSASIKALRNANLRRDDLYRRDETIQVKGNGYVQS 60
MHRLIFVYTLICANFCSCRDTSATPQSASIKALRNANLRRDDLYRRDETIQVKGNGYVQS
Sbjct: 1 MHRLIFVYTLICANFCSCRDTSATPQSASIKALRNANLRRDDLYRRDETIQVKGNGYVQS 60
Query: 61 PRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVEVEDISETSTII 120
PRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVEVEDISETSTII
Sbjct: 61 PRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVEVEDISETSTII 120
Query: 121 RGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYYSLLEDFQPAAASETNWESV 180
RGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYYSLLEDFQPAAASETNWESV
Sbjct: 121 RGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYYSLLEDFQPAAASETNWESV 180
Query: 181 TSSISGVSYNSPSVTDPTLIADALDKKIAEFDTVEDLLKYFNPESWQEDLENMYLDTPRY 240
TSSISGVSYNSPSVTDPTLIADALDKKIAEFDTVEDLLKYFNPESWQEDLENMYLDTPRY
Sbjct: 181 TSSISGVSYNSPSVTDPTLIADALDKKIAEFDTVEDLLKYFNPESWQEDLENMYLDTPRY 240
Query: 241 RGRSYHDRKSKVDLDRLNDDAKRYSCTPRNYSVNIREELKLANVVFFPRCLLVQRCGGNC 300
RGRSYHDRKSKVDLDRLNDDAKRYSCTPRNYSVNIREELKLANVVFFPRCLLVQRCGGNC
Sbjct: 241 RGRSYHDRKSKVDLDRLNDDAKRYSCTPRNYSVNIREELKLANVVFFPRCLLVQRCGGNC 300
Query: 301 GCGTVNWRSCTCNSGKTVKKYHEVLQFEPGHIKRRGRAKTMALVDIQLDHHERCDCICSS 360
GCGTVNWRSCTCNSGKTVKKYHEVLQFEPGHIKRRGRAKTMALVDIQLDHHERCDCICSS
Sbjct: 301 GCGTVNWRSCTCNSGKTVKKYHEVLQFEPGHIKRRGRAKTMALVDIQLDHHERCDCICSS 360
Query: 361 RPPR 364
RPPR
Sbjct: 361 RPPR 364
>gi|13376808 platelet derived growth factor D isoform 1 precursor
[Homo sapiens]
Length = 370
Score = 753 bits (1945), Expect = 0.0
Identities = 364/370 (98%), Positives = 364/370 (98%), Gaps = 6/370 (1%)
Query: 1 MHRLIFVYTLICANFCSCRDTSATPQSASIKALRNANLRRD------DLYRRDETIQVKG 54
MHRLIFVYTLICANFCSCRDTSATPQSASIKALRNANLRRD DLYRRDETIQVKG
Sbjct: 1 MHRLIFVYTLICANFCSCRDTSATPQSASIKALRNANLRRDESNHLTDLYRRDETIQVKG 60
Query: 55 NGYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVEVEDIS 114
NGYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVEVEDIS
Sbjct: 61 NGYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVEVEDIS 120
Query: 115 ETSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYYSLLEDFQPAAASE 174
ETSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYYSLLEDFQPAAASE
Sbjct: 121 ETSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYYSLLEDFQPAAASE 180
Query: 175 TNWESVTSSISGVSYNSPSVTDPTLIADALDKKIAEFDTVEDLLKYFNPESWQEDLENMY 234
TNWESVTSSISGVSYNSPSVTDPTLIADALDKKIAEFDTVEDLLKYFNPESWQEDLENMY
Sbjct: 181 TNWESVTSSISGVSYNSPSVTDPTLIADALDKKIAEFDTVEDLLKYFNPESWQEDLENMY 240
Query: 235 LDTPRYRGRSYHDRKSKVDLDRLNDDAKRYSCTPRNYSVNIREELKLANVVFFPRCLLVQ 294
LDTPRYRGRSYHDRKSKVDLDRLNDDAKRYSCTPRNYSVNIREELKLANVVFFPRCLLVQ
Sbjct: 241 LDTPRYRGRSYHDRKSKVDLDRLNDDAKRYSCTPRNYSVNIREELKLANVVFFPRCLLVQ 300
Query: 295 RCGGNCGCGTVNWRSCTCNSGKTVKKYHEVLQFEPGHIKRRGRAKTMALVDIQLDHHERC 354
RCGGNCGCGTVNWRSCTCNSGKTVKKYHEVLQFEPGHIKRRGRAKTMALVDIQLDHHERC
Sbjct: 301 RCGGNCGCGTVNWRSCTCNSGKTVKKYHEVLQFEPGHIKRRGRAKTMALVDIQLDHHERC 360
Query: 355 DCICSSRPPR 364
DCICSSRPPR
Sbjct: 361 DCICSSRPPR 370
>gi|9994187 platelet-derived growth factor C precursor [Homo
sapiens]
Length = 345
Score = 280 bits (717), Expect = 1e-75
Identities = 148/318 (46%), Positives = 202/318 (63%), Gaps = 27/318 (8%)
Query: 45 RRDETIQVKGNGYVQSPRFPNSYPRNLLLTWRLHS-QENTRIQLVFDNQFGLEEAENDIC 103
+ + I V NG + SPRFP++YPRN +L WRL + +EN IQL FD +FGLE+ E+DIC
Sbjct: 45 QHERIITVSTNGSIHSPRFPHTYPRNTVLVWRLVAVEENVWIQLTFDERFGLEDPEDDIC 104
Query: 104 RYDFVEVEDISETSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYYSL 163
+YDFVEVE+ S+ + I GRWCG VP + S+ NQI+I F SD+YF ++PGF I+Y++
Sbjct: 105 KYDFVEVEEPSDGT--ILGRWCGSGTVPGKQISKGNQIRIRFVSDEYFPSEPGFCIHYNI 162
Query: 164 LEDFQPAAASETNWESVTSSISGVSYNSPSVTDPTLIA-DALDKKIAEFDTVEDLLKYFN 222
+ T ++S PSV P+ + D L+ I F T+EDL++Y
Sbjct: 163 V------------MPQFTEAVS------PSVLPPSALPLDLLNNAITAFSTLEDLIRYLE 204
Query: 223 PESWQEDLENMYLDTPRYRGRSY-HDRKSKV-DLDRLNDDAKRYSCTPRNYSVNIREELK 280
PE WQ DLE++Y T + G+++ RKS+V DL+ L ++ + YSCTPRN+SV+IREELK
Sbjct: 205 PERWQLDLEDLYRPTWQLLGKAFVFGRKSRVVDLNLLTEEVRLYSCTPRNFSVSIREELK 264
Query: 281 LANVVFFPRCLLVQRCGGNCGCGTVNWRSCTCNSGKTVKKYHEVLQFEPGHIKRRGRAKT 340
+ +F+P CLLV+RCGGNC C N C C K KKYHEVLQ P K R
Sbjct: 265 RTDTIFWPGCLLVKRCGGNCACCLHNCNECQCVPSKVTKKYHEVLQLRP---KTGVRGLH 321
Query: 341 MALVDIQLDHHERCDCIC 358
+L D+ L+HHE CDC+C
Sbjct: 322 KSLTDVALEHHEECDCVC 339
>gi|5902808 bone morphogenetic protein 1 isoform 2 precursor [Homo
sapiens]
Length = 823
Score = 75.9 bits (185), Expect = 5e-14
Identities = 46/114 (40%), Positives = 65/114 (57%), Gaps = 6/114 (5%)
Query: 53 KGNGYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVEVED 112
K NG + SP +P YP N W+L + RI L FD E ND+C+YDFVEV
Sbjct: 597 KLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDF---FETEGNDVCKYDFVEVRS 653
Query: 113 ISETSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKI-YYSLLE 165
+ + G++CG E P I S+ N +++ FKSD+ V+K GFK ++S+LE
Sbjct: 654 GLTADSKLHGKFCG-SEKPEVITSQYNNMRVEFKSDN-TVSKKGFKAHFFSVLE 705
Score = 66.6 bits (161), Expect = 3e-11
Identities = 40/110 (36%), Positives = 64/110 (58%), Gaps = 7/110 (6%)
Query: 53 KGNGYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVEVED 112
K G++QSP +P+ Y + + WR+ E + L F + E +D C YD++EV D
Sbjct: 441 KDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQS---FEIERHDSCAYDYLEVRD 497
Query: 113 -ISETSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYY 161
SE+ST+I GR+CG+ E P IKS ++++ + F SD + K GF + +
Sbjct: 498 GHSESSTLI-GRYCGY-EKPDDIKSTSSRLWLKFVSDG-SINKAGFAVNF 544
Score = 60.5 bits (145), Expect = 2e-09
Identities = 37/116 (31%), Positives = 60/116 (51%), Gaps = 5/116 (4%)
Query: 48 ETIQVKGNGYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDF 107
ET+Q G SP +PN Y ++ WR+ +I L F + L+ + +C YD+
Sbjct: 324 ETLQ-DSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTS---LDLYRSRLCWYDY 379
Query: 108 VEVEDISETSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYYSL 163
VEV D +RGR+CG K +P I S +++ + F+S +V K F +Y ++
Sbjct: 380 VEVRDGFWRKAPLRGRFCGSK-LPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAI 434
>gi|4502421 bone morphogenetic protein 1 isoform 1 precursor [Homo
sapiens]
Length = 730
Score = 74.7 bits (182), Expect = 1e-13
Identities = 43/109 (39%), Positives = 61/109 (55%), Gaps = 5/109 (4%)
Query: 53 KGNGYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVEVED 112
K NG + SP +P YP N W+L + RI L FD E ND+C+YDFVEV
Sbjct: 597 KLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDF---FETEGNDVCKYDFVEVRS 653
Query: 113 ISETSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYY 161
+ + G++CG E P I S+ N +++ FKSD+ V+K GFK ++
Sbjct: 654 GLTADSKLHGKFCG-SEKPEVITSQYNNMRVEFKSDN-TVSKKGFKAHF 700
Score = 66.6 bits (161), Expect = 3e-11
Identities = 40/110 (36%), Positives = 64/110 (58%), Gaps = 7/110 (6%)
Query: 53 KGNGYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVEVED 112
K G++QSP +P+ Y + + WR+ E + L F + E +D C YD++EV D
Sbjct: 441 KDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQS---FEIERHDSCAYDYLEVRD 497
Query: 113 -ISETSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYY 161
SE+ST+I GR+CG+ E P IKS ++++ + F SD + K GF + +
Sbjct: 498 GHSESSTLI-GRYCGY-EKPDDIKSTSSRLWLKFVSDG-SINKAGFAVNF 544
Score = 60.5 bits (145), Expect = 2e-09
Identities = 37/116 (31%), Positives = 60/116 (51%), Gaps = 5/116 (4%)
Query: 48 ETIQVKGNGYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDF 107
ET+Q G SP +PN Y ++ WR+ +I L F + L+ + +C YD+
Sbjct: 324 ETLQ-DSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTS---LDLYRSRLCWYDY 379
Query: 108 VEVEDISETSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYYSL 163
VEV D +RGR+CG K +P I S +++ + F+S +V K F +Y ++
Sbjct: 380 VEVRDGFWRKAPLRGRFCGSK-LPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAI 434
>gi|5453579 bone morphogenetic protein 1 isoform 3 precursor [Homo
sapiens]
Length = 986
Score = 74.7 bits (182), Expect = 1e-13
Identities = 43/109 (39%), Positives = 61/109 (55%), Gaps = 5/109 (4%)
Query: 53 KGNGYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVEVED 112
K NG + SP +P YP N W+L + RI L FD E ND+C+YDFVEV
Sbjct: 597 KLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDF---FETEGNDVCKYDFVEVRS 653
Query: 113 ISETSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYY 161
+ + G++CG E P I S+ N +++ FKSD+ V+K GFK ++
Sbjct: 654 GLTADSKLHGKFCG-SEKPEVITSQYNNMRVEFKSDN-TVSKKGFKAHF 700
Score = 66.6 bits (161), Expect = 3e-11
Identities = 40/110 (36%), Positives = 64/110 (58%), Gaps = 7/110 (6%)
Query: 53 KGNGYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVEVED 112
K G++QSP +P+ Y + + WR+ E + L F + E +D C YD++EV D
Sbjct: 441 KDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQS---FEIERHDSCAYDYLEVRD 497
Query: 113 -ISETSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYY 161
SE+ST+I GR+CG+ E P IKS ++++ + F SD + K GF + +
Sbjct: 498 GHSESSTLI-GRYCGY-EKPDDIKSTSSRLWLKFVSDG-SINKAGFAVNF 544
Score = 60.5 bits (145), Expect = 2e-09
Identities = 37/116 (31%), Positives = 60/116 (51%), Gaps = 5/116 (4%)
Query: 48 ETIQVKGNGYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDF 107
ET+Q G SP +PN Y ++ WR+ +I L F + L+ + +C YD+
Sbjct: 324 ETLQ-DSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTS---LDLYRSRLCWYDY 379
Query: 108 VEVEDISETSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYYSL 163
VEV D +RGR+CG K +P I S +++ + F+S +V K F +Y ++
Sbjct: 380 VEVRDGFWRKAPLRGRFCGSK-LPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAI 434
Score = 50.4 bits (119), Expect = 2e-06
Identities = 30/104 (28%), Positives = 53/104 (50%), Gaps = 5/104 (4%)
Query: 55 NGYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVEVEDIS 114
+G + SP +P+ YP TW + S R++L F ++ C YD +EV D
Sbjct: 755 SGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTF---MEMDIESQPECAYDHLEVFDGR 811
Query: 115 ETSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFK 158
+ + GR+CG K+ P + + +++ + F SD+ V + GF+
Sbjct: 812 DAKAPVLGRFCGSKK-PEPVLATGSRMFLRFYSDN-SVQRKGFQ 853
Score = 48.5 bits (114), Expect = 9e-06
Identities = 32/98 (32%), Positives = 54/98 (55%), Gaps = 5/98 (5%)
Query: 65 NSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVEVEDISETSTIIRGRW 124
N+YP + W + ++E ++LVF F +EE E D C YD++E+ D +++ GR+
Sbjct: 882 NNYPGGVDCEWVIVAEEGYGVELVFQT-FEVEE-ETD-CGYDYMELFDGYDSTAPRLGRY 938
Query: 125 CGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYYS 162
CG P + S + + + F SDD + K GF + Y+
Sbjct: 939 CG-SGPPEEVYSAGDSVLVKFHSDD-TITKKGFHLRYT 974
>gi|6912724 tolloid-like 2 [Homo sapiens]
Length = 1015
Score = 73.9 bits (180), Expect = 2e-13
Identities = 43/109 (39%), Positives = 63/109 (57%), Gaps = 5/109 (4%)
Query: 53 KGNGYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVEVED 112
K NG + SP +P YP N W++ + RI L F+ F LE ND+C+YDFVEV
Sbjct: 626 KLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFE-VFELEG--NDVCKYDFVEVRS 682
Query: 113 ISETSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYY 161
+ GR+CG E P I S++N +++ FKSD+ V+K GF+ ++
Sbjct: 683 GLSPDAKLHGRFCG-SETPEVITSQSNNMRVEFKSDN-TVSKRGFRAHF 729
Score = 58.5 bits (140), Expect = 9e-09
Identities = 34/105 (32%), Positives = 53/105 (50%), Gaps = 5/105 (4%)
Query: 53 KGNGYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVEVED 112
K G +QSP +P+ Y + WR+ E + L F E +D C YD++EV D
Sbjct: 470 KDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQ---AFEIERHDSCAYDYLEVRD 526
Query: 113 ISETSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGF 157
+ + G +CG+ E P +KS +N++ + F SD + K GF
Sbjct: 527 GPTEESALIGHFCGY-EKPEDVKSSSNRLWMKFVSDG-SINKAGF 569
Score = 57.8 bits (138), Expect = 2e-08
Identities = 35/107 (32%), Positives = 58/107 (54%), Gaps = 5/107 (4%)
Query: 56 GYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVEVEDISE 115
G + SP +P+ YP TW + S R++L F N+F +E+ + C YD +E+ D +
Sbjct: 785 GTLASPNWPDKYPSRRECTWNISSTAGHRVKLTF-NEFEIEQHQE--CAYDHLEMYDGPD 841
Query: 116 TSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYYS 162
+ I GR+CG K+ P + S ++ + F S D V + GF+ +S
Sbjct: 842 SLAPILGRFCGSKKPDPTVASGSSMF-LRFYS-DASVQRKGFQAVHS 886
Score = 53.1 bits (126), Expect = 4e-07
Identities = 34/113 (30%), Positives = 55/113 (48%), Gaps = 5/113 (4%)
Query: 48 ETIQVKGNGYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDF 107
ET+Q G +P FPN YP WR+ +I L F + ++ ++ +C YD+
Sbjct: 353 ETLQ-DTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTS---MDLFKSRLCWYDY 408
Query: 108 VEVEDISETSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIY 160
VEV D + GR+CG K +P + S +++ + F+S + K F Y
Sbjct: 409 VEVRDGYWRKAPLLGRFCGDK-IPEPLVSTDSRLWVEFRSSSNILGKGFFAAY 460
Score = 43.1 bits (100), Expect = 4e-04
Identities = 43/164 (26%), Positives = 70/164 (42%), Gaps = 18/164 (10%)
Query: 11 ICANFCSCRDTSATPQSASIKALR---NANLRRDDLYRRDET---------IQVKGNGYV 58
I FC + T S S LR +A+++R T +Q K Y
Sbjct: 846 ILGRFCGSKKPDPTVASGSSMFLRFYSDASVQRKGFQAVHSTECGGRLKAEVQTK-ELYS 904
Query: 59 QSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVEVEDISETST 118
+ N+YP W + +++ ++L F EEA+ C YD++E D ++S
Sbjct: 905 HAQFGDNNYPSEARCDWVIVAEDGYGVELTFRTFEVEEEAD---CGYDYMEAYDGYDSSA 961
Query: 119 IIRGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYYS 162
GR+CG + I S + + I F++DD + K GF Y+
Sbjct: 962 PRLGRFCGSGPL-EEIYSAGDSLMIRFRTDD-TINKKGFHARYT 1003
>gi|22547221 tolloid-like 1 [Homo sapiens]
Length = 1013
Score = 68.6 bits (166), Expect = 9e-12
Identities = 40/109 (36%), Positives = 65/109 (59%), Gaps = 5/109 (4%)
Query: 53 KGNGYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVEVED 112
K NG + +P +P YP N W++ + RI + F+ F LE N++C+YD+VE+
Sbjct: 624 KLNGTITTPGWPKEYPPNKNCVWQVVAPTQYRISVKFEF-FELEG--NEVCKYDYVEIWS 680
Query: 113 ISETSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYY 161
+ + + G++CG EVP I S+ N ++I FKSD+ V+K GFK ++
Sbjct: 681 GLSSESKLHGKFCG-AEVPEVITSQFNNMRIEFKSDN-TVSKKGFKAHF 727
Score = 59.7 bits (143), Expect = 4e-09
Identities = 37/114 (32%), Positives = 61/114 (53%), Gaps = 5/114 (4%)
Query: 53 KGNGYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVEVED 112
K G +QSP +P+ Y W++ E+ + L F + F +E +N C YD++EV D
Sbjct: 468 KNEGQIQSPNYPDDYRPMKECVWKITVSESYHVGLTFQS-FEIERHDN--CAYDYLEVRD 524
Query: 113 ISETSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYYSLLED 166
+ ++ + GR+CG+ + P I+S +N + + F SD V K GF + ED
Sbjct: 525 GTSENSPLIGRFCGY-DKPEDIRSTSNTLWMKFVSDG-TVNKAGFAANFFKEED 576
Score = 59.3 bits (142), Expect = 5e-09
Identities = 38/117 (32%), Positives = 61/117 (52%), Gaps = 6/117 (5%)
Query: 48 ETIQVKGNGYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDF 107
ET+Q + NG + SP FPN YP WR+ +I L F ++ ++ +C YD+
Sbjct: 351 ETLQ-ESNGNLSSPGFPNGYPSYTHCIWRVSVTPGEKIVLNFTT---MDLYKSSLCWYDY 406
Query: 108 VEVEDISETSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYYSLL 164
+EV D + + GR+CG K +P + S +++ I F+S +V K GF Y +
Sbjct: 407 IEVRDGYWRKSPLLGRFCGDK-LPEVLTSTDSRMWIEFRSSSNWVGK-GFAAVYEAI 461
Score = 56.6 bits (135), Expect = 3e-08
Identities = 35/108 (32%), Positives = 59/108 (54%), Gaps = 5/108 (4%)
Query: 55 NGYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVEVEDIS 114
+G + SP +P+ YP TW + + RI+L F ++F +E+ + C YD +EV D
Sbjct: 782 SGLITSPNWPDKYPSRKECTWEISATPGHRIKLAF-SEFEIEQHQE--CAYDHLEVFDGE 838
Query: 115 ETSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYYS 162
+ I GR CG+K +P + + N++ + F S D V + GF+ +S
Sbjct: 839 TEKSPILGRLCGNK-IPDPLVATGNKMFVRFVS-DASVQRKGFQATHS 884
Score = 50.8 bits (120), Expect = 2e-06
Identities = 34/97 (35%), Positives = 52/97 (53%), Gaps = 5/97 (5%)
Query: 65 NSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVEVEDISETSTIIRGRW 124
N+YP + W L S+ +R++L F EEA+ C YD+VE+ D +++ + GR+
Sbjct: 909 NNYPGQVDCEWLLVSERGSRLELSFQTFEVEEEAD---CGYDYVELFDGLDSTAVGLGRF 965
Query: 125 CGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYY 161
CG P I S + + I F +DD + K GF I Y
Sbjct: 966 CG-SGPPEEIYSIGDSVLIHFHTDD-TINKKGFHIRY 1000
>gi|66864913 neuropilin 1 isoform c [Homo sapiens]
Length = 609
Score = 65.1 bits (157), Expect = 1e-10
Identities = 51/171 (29%), Positives = 84/171 (49%), Gaps = 9/171 (5%)
Query: 48 ETIQVKGNGYVQSPRFPNSYPRNLLLTWRLHSQEN-TRIQLVFDNQFGLEEAENDICRYD 106
+TI+++ GY+ SP +P+SY + W + + + RI + F+ F LE+ + C+YD
Sbjct: 29 DTIKIESPGYLTSPGYPHSYHPSEKCEWLIQAPDPYQRIMINFNPHFDLEDRD---CKYD 85
Query: 107 FVEVEDISETSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYYSLLED 166
+VEV D + RG++CG K PP + S + I F S DY GF I Y + +
Sbjct: 86 YVEVFDGENENGHFRGKFCG-KIAPPPVVSSGPFLFIKFVS-DYETHGAGFSIRYEIFKR 143
Query: 167 FQPAAASETNWESVTSSISGVSYNSPSVTDPTLI--ADALDKKIAEFDTVE 215
+ + T V S G P+ + T I A + + I EF++ +
Sbjct: 144 GPECSQNYTTPSGVIKS-PGFPEKYPNSLECTYIVFAPKMSEIILEFESFD 193
>gi|66912178 neuropilin 1 isoform b [Homo sapiens]
Length = 644
Score = 65.1 bits (157), Expect = 1e-10
Identities = 51/171 (29%), Positives = 84/171 (49%), Gaps = 9/171 (5%)
Query: 48 ETIQVKGNGYVQSPRFPNSYPRNLLLTWRLHSQEN-TRIQLVFDNQFGLEEAENDICRYD 106
+TI+++ GY+ SP +P+SY + W + + + RI + F+ F LE+ + C+YD
Sbjct: 29 DTIKIESPGYLTSPGYPHSYHPSEKCEWLIQAPDPYQRIMINFNPHFDLEDRD---CKYD 85
Query: 107 FVEVEDISETSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYYSLLED 166
+VEV D + RG++CG K PP + S + I F S DY GF I Y + +
Sbjct: 86 YVEVFDGENENGHFRGKFCG-KIAPPPVVSSGPFLFIKFVS-DYETHGAGFSIRYEIFKR 143
Query: 167 FQPAAASETNWESVTSSISGVSYNSPSVTDPTLI--ADALDKKIAEFDTVE 215
+ + T V S G P+ + T I A + + I EF++ +
Sbjct: 144 GPECSQNYTTPSGVIKS-PGFPEKYPNSLECTYIVFAPKMSEIILEFESFD 193
>gi|182508169 neuropilin 1 isoform a [Homo sapiens]
Length = 923
Score = 65.1 bits (157), Expect = 1e-10
Identities = 51/171 (29%), Positives = 84/171 (49%), Gaps = 9/171 (5%)
Query: 48 ETIQVKGNGYVQSPRFPNSYPRNLLLTWRLHSQEN-TRIQLVFDNQFGLEEAENDICRYD 106
+TI+++ GY+ SP +P+SY + W + + + RI + F+ F LE+ + C+YD
Sbjct: 29 DTIKIESPGYLTSPGYPHSYHPSEKCEWLIQAPDPYQRIMINFNPHFDLEDRD---CKYD 85
Query: 107 FVEVEDISETSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYYSLLED 166
+VEV D + RG++CG K PP + S + I F S DY GF I Y + +
Sbjct: 86 YVEVFDGENENGHFRGKFCG-KIAPPPVVSSGPFLFIKFVS-DYETHGAGFSIRYEIFKR 143
Query: 167 FQPAAASETNWESVTSSISGVSYNSPSVTDPTLI--ADALDKKIAEFDTVE 215
+ + T V S G P+ + T I A + + I EF++ +
Sbjct: 144 GPECSQNYTTPSGVIKS-PGFPEKYPNSLECTYIVFAPKMSEIILEFESFD 193
>gi|126091152 cubilin [Homo sapiens]
Length = 3623
Score = 63.9 bits (154), Expect = 2e-10
Identities = 45/116 (38%), Positives = 61/116 (52%), Gaps = 9/116 (7%)
Query: 50 IQVKGNGYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVE 109
I + G +QSP PN YP + TW + Q N I L+F+ F LE N C D++E
Sbjct: 935 ILTESTGTIQSPGHPNVYPHGINCTWHILVQPNHLIHLMFET-FHLEFHYN--CTNDYLE 991
Query: 110 VEDI-SETSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYYSLL 164
V D SETS GR+CG K +PP + S N + + F +D +A GF I Y +
Sbjct: 992 VYDTDSETSL---GRYCG-KSIPPSLTSSGNSLMLVFVTDS-DLAYEGFLINYEAI 1042
Score = 56.2 bits (134), Expect = 4e-08
Identities = 35/110 (31%), Positives = 58/110 (52%), Gaps = 4/110 (3%)
Query: 56 GYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVEVEDISE 115
GYV SP P++YP + W L + TRIQL F+++F +E N C +++E+ D +
Sbjct: 2230 GYVTSPNHPHNYPPHADCIWILAAPPETRIQLQFEDRFDIEVTPN--CTSNYLELRDGVD 2287
Query: 116 TSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYYSLLE 165
+ I ++CG +P S + + F+SD+ GFK YS+ +
Sbjct: 2288 SDAPILSKFCG-TSLPSSQWSSGEVMYLRFRSDN-SPTHVGFKAKYSIAQ 2335
Score = 51.6 bits (122), Expect = 1e-06
Identities = 36/106 (33%), Positives = 54/106 (50%), Gaps = 4/106 (3%)
Query: 56 GYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVEVEDISE 115
G SP FPN+YP N +R+ + I + F N F LEEA + DF+E+ D
Sbjct: 1057 GTFTSPNFPNNYPNNWECIYRITVRTGQLIAVHFTN-FSLEEAIGNYYT-DFLEIRDGGY 1114
Query: 116 TSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYY 161
+ + G + G +PP I S +N++ + FKSD + GF Y+
Sbjct: 1115 EKSPLLGIFYG-SNLPPTIISHSNKLWLKFKSDQ-IDTRSGFSAYW 1158
Score = 51.6 bits (122), Expect = 1e-06
Identities = 31/91 (34%), Positives = 46/91 (50%), Gaps = 3/91 (3%)
Query: 58 VQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVEVEDISETS 117
V SPRFP +YP N +W + +Q + F LE + C DFVE+ D
Sbjct: 1632 VSSPRFPANYPNNQNCSWIIQAQPPLNHITLSFTHFELERSTT--CARDFVEILDGGHED 1689
Query: 118 TIIRGRWCGHKEVPPRIKSRTNQIKITFKSD 148
+RGR+CG ++P I S ++ + + F SD
Sbjct: 1690 APLRGRYCG-TDMPHPITSFSSALTLRFVSD 1719
Score = 50.8 bits (120), Expect = 2e-06
Identities = 29/108 (26%), Positives = 59/108 (54%), Gaps = 6/108 (5%)
Query: 55 NGYVQSPRFPNS-YPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVEVEDI 113
+G + SP + + YP ++ + + ++ I+L F + + + C +D++ + D
Sbjct: 3045 SGIITSPAYSYADYPNDMHCLYTITVSDDKVIELKFSD---FDVVPSTSCSHDYLAIYDG 3101
Query: 114 SETSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYY 161
+ TS + G++CG K PP +KS N + + FK+D + AK G+K+ +
Sbjct: 3102 ANTSDPLLGKFCGSKR-PPNVKSSNNSMLLVFKTDSFQTAK-GWKMSF 3147
Score = 50.8 bits (120), Expect = 2e-06
Identities = 33/110 (30%), Positives = 63/110 (57%), Gaps = 5/110 (4%)
Query: 53 KGNGYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVEVED 112
K G ++SP +P++Y + T L + +N I L F + G+E + CR DF+EV +
Sbjct: 3401 KAFGNLRSPGWPDNYDNDKDCTVTLTAPQNHTISLFF-HSLGIENSVE--CRNDFLEVRN 3457
Query: 113 ISETSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYYS 162
S +++ + G++CG +P + S+ N++ + FKSD + G++I ++
Sbjct: 3458 GSNSNSPLLGKYCG-TLLPNPVFSQNNELYLRFKSDS-VTSDRGYEIIWT 3505
Score = 49.3 bits (116), Expect = 5e-06
Identities = 31/99 (31%), Positives = 52/99 (52%), Gaps = 4/99 (4%)
Query: 50 IQVKGNGYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVE 109
IQ+ +G + SP +PN+Y + L + + I L F + F +E + C +D V
Sbjct: 2692 IQIGDSGVITSPNYPNAYDSLTHCSSLLEAPQGHTITLTF-SDFDIE--PHTTCAWDSVT 2748
Query: 110 VEDISETSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSD 148
V + + I G++CG+ P I+S +NQ+ +TF SD
Sbjct: 2749 VRNGGSPESPIIGQYCGNSN-PRTIQSGSNQLVVTFNSD 2786
Score = 48.9 bits (115), Expect = 7e-06
Identities = 26/72 (36%), Positives = 43/72 (59%), Gaps = 4/72 (5%)
Query: 56 GYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVEVEDISE 115
G SP +P+ YP N+ W + S R+QL F + F LE++++ C DFVE+ + +
Sbjct: 1747 GIFNSPGYPDIYPPNVECVWNIVSSPGNRLQLSFIS-FQLEDSQD--CSRDFVEIREGNA 1803
Query: 116 TSTIIRGRWCGH 127
T ++ GR+CG+
Sbjct: 1804 TGHLV-GRYCGN 1814
Score = 46.2 bits (108), Expect = 5e-05
Identities = 27/95 (28%), Positives = 46/95 (48%), Gaps = 4/95 (4%)
Query: 51 QVKGNGYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVEV 110
++ G G ++SP FPN YP W +H ++ Q++ N E + C D+VE+
Sbjct: 820 ELTGEGVIRSPFFPNVYPGERTCRWTIHQPQS---QVILLNFTVFEIGSSAHCETDYVEI 876
Query: 111 EDISETSTIIRGRWCGHKEVPPRIKSRTNQIKITF 145
S + ++CG ++P I S N + +TF
Sbjct: 877 GSSSILGSPENKKYCG-TDIPSFITSVYNFLYVTF 910
Score = 46.2 bits (108), Expect = 5e-05
Identities = 34/113 (30%), Positives = 53/113 (46%), Gaps = 8/113 (7%)
Query: 56 GYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVEVEDISE 115
G SP +PN P + WR+ + E RI L+F+N L A + C + V V +
Sbjct: 2461 GTFTSPNYPNPNPHGRICEWRITAPEGRRITLMFNN---LRLATHPSCNNEHVIVFNGIR 2517
Query: 116 TSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKP--GFKIYYSLLED 166
+++ + C V IKS N +K+ F +D ++P GF Y+ ED
Sbjct: 2518 SNSPQLEKLCSSVNVSNEIKSSGNTMKVIFFTDG---SRPYGGFTASYTSSED 2567
Score = 43.5 bits (101), Expect = 3e-04
Identities = 37/129 (28%), Positives = 56/129 (43%), Gaps = 7/129 (5%)
Query: 67 YPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAEN-DICRYDFVEVEDISETSTIIRGRWC 125
Y +NL W + + N I L F N F LE A C YD+V++ D + + G +C
Sbjct: 3179 YDKNLNCVWIIIAPVNKVIHLTF-NTFALEAASTRQRCLYDYVKLYDGDSENANLAGTFC 3237
Query: 126 GHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYYSLLEDFQPAAASETNWESVTSSIS 185
G VP S N + + F S D + + GF Y+++ D W +IS
Sbjct: 3238 G-STVPAPFISSGNFLTVQFIS-DLTLEREGFNATYTIM-DMPCGGTYNATW--TPQNIS 3292
Query: 186 GVSYNSPSV 194
+ + P V
Sbjct: 3293 SPNSSDPDV 3301
Score = 42.4 bits (98), Expect = 7e-04
Identities = 23/96 (23%), Positives = 46/96 (47%), Gaps = 3/96 (3%)
Query: 55 NGYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVEV-EDI 113
NG ++SP +P ++P N +W + ++ +++ FDN F + + C+ FV+V
Sbjct: 2813 NGTIRSPHWPQNFPENSRCSWTAITHKSKHLEISFDNNFLIPSGDGQ-CQNSFVKVWAGT 2871
Query: 114 SETSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDD 149
E + CG+ P + + +N F+S +
Sbjct: 2872 EEVDKALLATGCGN-VAPGPVITPSNTFTAVFQSQE 2906
Score = 41.6 bits (96), Expect = 0.001
Identities = 35/140 (25%), Positives = 60/140 (42%), Gaps = 23/140 (16%)
Query: 56 GYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVEVEDISE 115
G SP FPN YP N W + + + IQL + F +E + C +D +E+ +
Sbjct: 1400 GSFSSPGFPNRYPPNKECIWYIRTDPGSSIQLTI-HDFDVE--YHSRCNFDVLEIYGGPD 1456
Query: 116 TSTIIRGRWCGHK--EVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYYSLLEDFQPAAAS 173
+ + C + E P ++ S N++ I FK+ D + GF
Sbjct: 1457 FHSPRIAQLCTQRSPENPMQVSSTGNELAIRFKT-DLSINGRGF---------------- 1499
Query: 174 ETNWESVTSSISGVSYNSPS 193
+W++VT G+ + +PS
Sbjct: 1500 NASWQAVTGGCGGI-FQAPS 1518
Score = 40.4 bits (93), Expect = 0.003
Identities = 28/94 (29%), Positives = 46/94 (48%), Gaps = 9/94 (9%)
Query: 55 NGYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVEVEDIS 114
+G + SP +P+ Y N +W + N R+ L F F LE ++ I YD +
Sbjct: 1518 SGEIHSPNYPSPYRSNTDCSWVIRVDRNHRVLLNF-TDFDLEPQDSCIMAYDGL------ 1570
Query: 115 ETSTIIR-GRWCGHKEVPPRIKSRTNQIKITFKS 147
+ST+ R R CG +++ I S N + + F+S
Sbjct: 1571 -SSTMSRLARTCGREQLANPIVSSGNSLFLRFQS 1603
Score = 39.7 bits (91), Expect = 0.004
Identities = 27/106 (25%), Positives = 48/106 (45%), Gaps = 5/106 (4%)
Query: 56 GYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVEVEDISE 115
G ++SP +P +YP W + + + + F L +D C D++E+ D
Sbjct: 599 GSIKSPGYPGNYPPGRDCVWIVVTSPDLLVTFTFGT---LSLEHHDDCNKDYLEIRDGPL 655
Query: 116 TSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYY 161
+ G++C VPP +++ +I F SD ++ GF I Y
Sbjct: 656 YQDPLLGKFCTTFSVPP-LQTTGPFARIHFHSDSQ-ISDQGFHITY 699
Score = 39.3 bits (90), Expect = 0.006
Identities = 27/112 (24%), Positives = 51/112 (45%), Gaps = 8/112 (7%)
Query: 56 GYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVEVEDISE 115
G + SP++P +YP NL +W + Q I + F+ F + ++ + D++ + + +
Sbjct: 2101 GIITSPKYPETYPSNLNCSWHVLVQSGLTIAVHFEQPFQIPNGDSSCNQGDYLVLRNGPD 2160
Query: 116 TSTII------RGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYY 161
+ G +CG + + NQ+ + F S D+ GFKI Y
Sbjct: 2161 ICSPPLGPPGGNGHFCG-SHASSTLFTSDNQMFVQFIS-DHSNEGQGFKIKY 2210
Score = 38.5 bits (88), Expect = 0.010
Identities = 31/107 (28%), Positives = 50/107 (46%), Gaps = 5/107 (4%)
Query: 55 NGYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVEVEDIS 114
+G SP +P Y + W L S + +L F F LE N C D++ V D
Sbjct: 1173 SGTFISPNYPMPYYHSSECYWWLKSSHGSAFELEF-KDFHLEHHPN--CTLDYLAVYDGP 1229
Query: 115 ETSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYY 161
+++ + + CG E PP I+S + + I ++D+ + GFK Y
Sbjct: 1230 SSNSHLLTQLCG-DEKPPLIRSSGDSMFIKLRTDEGQQGR-GFKAEY 1274
Score = 37.0 bits (84), Expect = 0.028
Identities = 28/101 (27%), Positives = 48/101 (47%), Gaps = 6/101 (5%)
Query: 57 YVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVEVEDISET 116
++ SP +P+SY + TW + + ++T ++L N L+ + C YD + + D
Sbjct: 1990 FLFSPGWPDSYSNRVDCTWLIQAPDST-VEL---NILSLDIESHRTCAYDSLVIRDGDNN 2045
Query: 117 STIIRGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGF 157
CG +E+P I+S + I F SD V + GF
Sbjct: 2046 LAQQLAVLCG-REIPGPIRSTGEYMFIRFTSDS-SVTRAGF 2084
Score = 35.4 bits (80), Expect = 0.081
Identities = 25/106 (23%), Positives = 49/106 (46%), Gaps = 8/106 (7%)
Query: 56 GYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVEVEDISE 115
G ++S +PN Y N W + + + F F LE N C D++E+ D
Sbjct: 1289 GILESIGYPNPYSENQHCNWTIRATTGNTVNYTF-LAFDLEHHIN--CSTDYLELYDGPR 1345
Query: 116 TSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYY 161
GR+CG ++PP + ++++++ +D + GF++ +
Sbjct: 1346 Q----MGRYCG-VDLPPPGSTTSSKLQVLLLTDGVGRREKGFQMQW 1386
Score = 33.1 bits (74), Expect = 0.40
Identities = 23/93 (24%), Positives = 40/93 (43%), Gaps = 3/93 (3%)
Query: 56 GYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVEVEDISE 115
G SP +P +YP N W L + +LV N + + + C +++ + D
Sbjct: 3520 GSFTSPGYPGTYPNNTYCEWVLVAPAG---RLVTINFYFISIDDPGDCVQNYLTLYDGPN 3576
Query: 116 TSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSD 148
S+ G +CG + +NQ+ I F +D
Sbjct: 3577 ASSPSSGPYCGGDTSIAPFVASSNQVFIKFHAD 3609
Score = 32.0 bits (71), Expect = 0.89
Identities = 24/100 (24%), Positives = 39/100 (39%), Gaps = 5/100 (5%)
Query: 55 NGYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVEVEDIS 114
+G V SP +P +YP N W ++ + +V ++ E C YD + + D
Sbjct: 1860 HGKVASPFWPENYPHNSNYQWTVNVNAS---HVVHGRILEMDIEEIQNCYYDKLRIYDGP 1916
Query: 115 ETSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAK 154
+ G +CG + S N + F SD K
Sbjct: 1917 SIHARLIGAYCGTQ--TESFSSTGNSLTFHFYSDSSISGK 1954
Score = 29.3 bits (64), Expect = 5.8
Identities = 19/75 (25%), Positives = 37/75 (49%), Gaps = 4/75 (5%)
Query: 67 YPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVEVEDISETSTIIRGRWCG 126
Y ++ W + ++ +++ F F LE +N C ++F++V D +S GR+CG
Sbjct: 494 YVHDVNCFWVIKTEMGKVLRITF-TFFRLESMDN--CPHEFLQVYDGDSSSAFQLGRFCG 550
Query: 127 HKEVPPRIKSRTNQI 141
+P + S N +
Sbjct: 551 -SSLPHELLSSDNAL 564
>gi|41872572 neuropilin 2 isoform 3 precursor [Homo sapiens]
Length = 909
Score = 63.2 bits (152), Expect = 4e-10
Identities = 38/114 (33%), Positives = 60/114 (52%), Gaps = 6/114 (5%)
Query: 53 KGNGYVQSPRFPNSYPRNLLLTWRLHSQE-NTRIQLVFDNQFGLEEAENDICRYDFVEVE 111
K GY+ SP +P YP + W +++ E N +I L F+ F +E+ + C+YDF+E+
Sbjct: 35 KDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHD---CKYDFIEIR 91
Query: 112 DISETSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYYSLLE 165
D S + G+ CG+ PP I S + + I F S DY GF + Y + +
Sbjct: 92 DGDSESADLLGKHCGN-IAPPTIISSGSMLYIKFTS-DYARQGAGFSLRYEIFK 143
Score = 60.1 bits (144), Expect = 3e-09
Identities = 45/124 (36%), Positives = 68/124 (54%), Gaps = 14/124 (11%)
Query: 55 NGYVQSPRFPNSYPRNLLLTWRLHSQENTRI---QLVFDNQFG-LEEAENDICRYDFVEV 110
NG ++SP FP YP NL T+ + ++ I L+FD + L+ E D C+YD++++
Sbjct: 157 NGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGD-CKYDWLDI 215
Query: 111 ED-ISETSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYYSL-----L 164
D I +I G++CG K P ++S T + +TF + D VAK GF Y L L
Sbjct: 216 WDGIPHVGPLI-GKYCGTK-TPSELRSSTGILSLTFHT-DMAVAKDGFSARYYLVHQEPL 272
Query: 165 EDFQ 168
E+FQ
Sbjct: 273 ENFQ 276
>gi|41872567 neuropilin 2 isoform 5 precursor [Homo sapiens]
Length = 901
Score = 63.2 bits (152), Expect = 4e-10
Identities = 38/114 (33%), Positives = 60/114 (52%), Gaps = 6/114 (5%)
Query: 53 KGNGYVQSPRFPNSYPRNLLLTWRLHSQE-NTRIQLVFDNQFGLEEAENDICRYDFVEVE 111
K GY+ SP +P YP + W +++ E N +I L F+ F +E+ + C+YDF+E+
Sbjct: 35 KDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHD---CKYDFIEIR 91
Query: 112 DISETSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYYSLLE 165
D S + G+ CG+ PP I S + + I F S DY GF + Y + +
Sbjct: 92 DGDSESADLLGKHCGN-IAPPTIISSGSMLYIKFTS-DYARQGAGFSLRYEIFK 143
Score = 60.1 bits (144), Expect = 3e-09
Identities = 45/124 (36%), Positives = 68/124 (54%), Gaps = 14/124 (11%)
Query: 55 NGYVQSPRFPNSYPRNLLLTWRLHSQENTRI---QLVFDNQFG-LEEAENDICRYDFVEV 110
NG ++SP FP YP NL T+ + ++ I L+FD + L+ E D C+YD++++
Sbjct: 157 NGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGD-CKYDWLDI 215
Query: 111 ED-ISETSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYYSL-----L 164
D I +I G++CG K P ++S T + +TF + D VAK GF Y L L
Sbjct: 216 WDGIPHVGPLI-GKYCGTK-TPSELRSSTGILSLTFHT-DMAVAKDGFSARYYLVHQEPL 272
Query: 165 EDFQ 168
E+FQ
Sbjct: 273 ENFQ 276
>gi|41872562 neuropilin 2 isoform 1 precursor [Homo sapiens]
Length = 931
Score = 63.2 bits (152), Expect = 4e-10
Identities = 38/114 (33%), Positives = 60/114 (52%), Gaps = 6/114 (5%)
Query: 53 KGNGYVQSPRFPNSYPRNLLLTWRLHSQE-NTRIQLVFDNQFGLEEAENDICRYDFVEVE 111
K GY+ SP +P YP + W +++ E N +I L F+ F +E+ + C+YDF+E+
Sbjct: 35 KDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHD---CKYDFIEIR 91
Query: 112 DISETSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYYSLLE 165
D S + G+ CG+ PP I S + + I F S DY GF + Y + +
Sbjct: 92 DGDSESADLLGKHCGN-IAPPTIISSGSMLYIKFTS-DYARQGAGFSLRYEIFK 143
Score = 60.1 bits (144), Expect = 3e-09
Identities = 45/124 (36%), Positives = 68/124 (54%), Gaps = 14/124 (11%)
Query: 55 NGYVQSPRFPNSYPRNLLLTWRLHSQENTRI---QLVFDNQFG-LEEAENDICRYDFVEV 110
NG ++SP FP YP NL T+ + ++ I L+FD + L+ E D C+YD++++
Sbjct: 157 NGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGD-CKYDWLDI 215
Query: 111 ED-ISETSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYYSL-----L 164
D I +I G++CG K P ++S T + +TF + D VAK GF Y L L
Sbjct: 216 WDGIPHVGPLI-GKYCGTK-TPSELRSSTGILSLTFHT-DMAVAKDGFSARYYLVHQEPL 272
Query: 165 EDFQ 168
E+FQ
Sbjct: 273 ENFQ 276
>gi|41872557 neuropilin 2 isoform 6 precursor [Homo sapiens]
Length = 555
Score = 63.2 bits (152), Expect = 4e-10
Identities = 38/114 (33%), Positives = 60/114 (52%), Gaps = 6/114 (5%)
Query: 53 KGNGYVQSPRFPNSYPRNLLLTWRLHSQE-NTRIQLVFDNQFGLEEAENDICRYDFVEVE 111
K GY+ SP +P YP + W +++ E N +I L F+ F +E+ + C+YDF+E+
Sbjct: 35 KDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHD---CKYDFIEIR 91
Query: 112 DISETSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYYSLLE 165
D S + G+ CG+ PP I S + + I F S DY GF + Y + +
Sbjct: 92 DGDSESADLLGKHCGN-IAPPTIISSGSMLYIKFTS-DYARQGAGFSLRYEIFK 143
Score = 60.1 bits (144), Expect = 3e-09
Identities = 45/124 (36%), Positives = 68/124 (54%), Gaps = 14/124 (11%)
Query: 55 NGYVQSPRFPNSYPRNLLLTWRLHSQENTRI---QLVFDNQFG-LEEAENDICRYDFVEV 110
NG ++SP FP YP NL T+ + ++ I L+FD + L+ E D C+YD++++
Sbjct: 157 NGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGD-CKYDWLDI 215
Query: 111 ED-ISETSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYYSL-----L 164
D I +I G++CG K P ++S T + +TF + D VAK GF Y L L
Sbjct: 216 WDGIPHVGPLI-GKYCGTK-TPSELRSSTGILSLTFHT-DMAVAKDGFSARYYLVHQEPL 272
Query: 165 EDFQ 168
E+FQ
Sbjct: 273 ENFQ 276
>gi|41872544 neuropilin 2 isoform 4 precursor [Homo sapiens]
Length = 906
Score = 63.2 bits (152), Expect = 4e-10
Identities = 38/114 (33%), Positives = 60/114 (52%), Gaps = 6/114 (5%)
Query: 53 KGNGYVQSPRFPNSYPRNLLLTWRLHSQE-NTRIQLVFDNQFGLEEAENDICRYDFVEVE 111
K GY+ SP +P YP + W +++ E N +I L F+ F +E+ + C+YDF+E+
Sbjct: 35 KDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHD---CKYDFIEIR 91
Query: 112 DISETSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYYSLLE 165
D S + G+ CG+ PP I S + + I F S DY GF + Y + +
Sbjct: 92 DGDSESADLLGKHCGN-IAPPTIISSGSMLYIKFTS-DYARQGAGFSLRYEIFK 143
Score = 60.1 bits (144), Expect = 3e-09
Identities = 45/124 (36%), Positives = 68/124 (54%), Gaps = 14/124 (11%)
Query: 55 NGYVQSPRFPNSYPRNLLLTWRLHSQENTRI---QLVFDNQFG-LEEAENDICRYDFVEV 110
NG ++SP FP YP NL T+ + ++ I L+FD + L+ E D C+YD++++
Sbjct: 157 NGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGD-CKYDWLDI 215
Query: 111 ED-ISETSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYYSL-----L 164
D I +I G++CG K P ++S T + +TF + D VAK GF Y L L
Sbjct: 216 WDGIPHVGPLI-GKYCGTK-TPSELRSSTGILSLTFHT-DMAVAKDGFSARYYLVHQEPL 272
Query: 165 EDFQ 168
E+FQ
Sbjct: 273 ENFQ 276
>gi|41872533 neuropilin 2 isoform 2 precursor [Homo sapiens]
Length = 926
Score = 63.2 bits (152), Expect = 4e-10
Identities = 38/114 (33%), Positives = 60/114 (52%), Gaps = 6/114 (5%)
Query: 53 KGNGYVQSPRFPNSYPRNLLLTWRLHSQE-NTRIQLVFDNQFGLEEAENDICRYDFVEVE 111
K GY+ SP +P YP + W +++ E N +I L F+ F +E+ + C+YDF+E+
Sbjct: 35 KDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHD---CKYDFIEIR 91
Query: 112 DISETSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYYSLLE 165
D S + G+ CG+ PP I S + + I F S DY GF + Y + +
Sbjct: 92 DGDSESADLLGKHCGN-IAPPTIISSGSMLYIKFTS-DYARQGAGFSLRYEIFK 143
Score = 60.1 bits (144), Expect = 3e-09
Identities = 45/124 (36%), Positives = 68/124 (54%), Gaps = 14/124 (11%)
Query: 55 NGYVQSPRFPNSYPRNLLLTWRLHSQENTRI---QLVFDNQFG-LEEAENDICRYDFVEV 110
NG ++SP FP YP NL T+ + ++ I L+FD + L+ E D C+YD++++
Sbjct: 157 NGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGD-CKYDWLDI 215
Query: 111 ED-ISETSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYYSL-----L 164
D I +I G++CG K P ++S T + +TF + D VAK GF Y L L
Sbjct: 216 WDGIPHVGPLI-GKYCGTK-TPSELRSSTGILSLTFHT-DMAVAKDGFSARYYLVHQEPL 272
Query: 165 EDFQ 168
E+FQ
Sbjct: 273 ENFQ 276
>gi|38045890 CUB and Sushi multiple domains 3 isoform 2 [Homo
sapiens]
Length = 3667
Score = 62.0 bits (149), Expect = 8e-10
Identities = 39/111 (35%), Positives = 57/111 (51%), Gaps = 9/111 (8%)
Query: 55 NGYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVEVEDIS 114
NG ++SP FP YP TW + ++E RIQ+VF + F LEE YD++ + D
Sbjct: 33 NGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQS-FALEE------EYDYLSLYDGH 85
Query: 115 ETSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYYSLLE 165
T R R G +PP + S + + S D+ V+ GFK+YY L+
Sbjct: 86 PHPTNFRTRLTGF-HLPPPVTSTKSVFSLRLTS-DFAVSAHGFKVYYEELQ 134
Score = 53.1 bits (126), Expect = 4e-07
Identities = 32/94 (34%), Positives = 48/94 (51%), Gaps = 12/94 (12%)
Query: 55 NGYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVEVEDIS 114
+G + SP FPN Y N TW + ++ I L+F F +EE +YD++E+E S
Sbjct: 209 SGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIF-TDFQMEE------KYDYLEIEG-S 260
Query: 115 ETSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSD 148
E TI W +PP I S N +++ F +D
Sbjct: 261 EPPTI----WLSGMNIPPPIISNKNWLRLHFVTD 290
Score = 50.1 bits (118), Expect = 3e-06
Identities = 39/108 (36%), Positives = 56/108 (51%), Gaps = 11/108 (10%)
Query: 55 NGYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVEVED-I 113
+G + SP FP +YP +L TW ++ + L F N F E +D++EV
Sbjct: 2079 SGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVN-FSTETI------HDYLEVRSGS 2131
Query: 114 SETSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYY 161
SETST+I GR G ++P + S T++ + F S DY K GF I Y
Sbjct: 2132 SETSTVI-GRLSG-PQIPSSLFSTTHETSLYFHS-DYSQNKQGFHIVY 2176
Score = 45.4 bits (106), Expect = 8e-05
Identities = 31/107 (28%), Positives = 56/107 (52%), Gaps = 9/107 (8%)
Query: 55 NGYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVEVEDIS 114
+G++ SP FP+ YP + W + + I L F + F +E YDF+ + D
Sbjct: 1556 SGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFIS-FSIEP------NYDFLYIYDGP 1608
Query: 115 ETSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYY 161
++++ + G + K +P RI+S +N + + F+SD V+ GF + Y
Sbjct: 1609 DSNSPLIGSFQDSK-LPERIESSSNTMHLAFRSDG-SVSYTGFHLEY 1653
Score = 34.7 bits (78), Expect = 0.14
Identities = 31/113 (27%), Positives = 49/113 (43%), Gaps = 15/113 (13%)
Query: 53 KGNGYVQSPRFPNSYPRNLLLTWRLHSQENTRIQL---VFDNQFGLEEAENDICRYDFVE 109
+ +G + SP +P Y NL W + + L FD EA +DI R
Sbjct: 1381 ESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDT-----EASHDILR----- 1430
Query: 110 VEDISETSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYYS 162
V D + ++ G +P I S N + I F +D ++++K GF I +S
Sbjct: 1431 VWDGPPENDMLLKEISGSL-IPEGIHSTLNIVTIQFDTD-FYISKSGFAIQFS 1481
Score = 31.6 bits (70), Expect = 1.2
Identities = 26/94 (27%), Positives = 43/94 (45%), Gaps = 8/94 (8%)
Query: 55 NGYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVEVEDIS 114
NG + SP +P+ YP W + I + F + + E YDF+ V D
Sbjct: 2251 NGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYI----NFTVLQTEP---IYDFITVWDGP 2303
Query: 115 ETSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSD 148
+ ++ G++ G+ + + S +NQI I F SD
Sbjct: 2304 DQNSPQIGQFSGNTAL-ESVYSTSNQILIKFHSD 2336
Score = 30.0 bits (66), Expect = 3.4
Identities = 29/112 (25%), Positives = 53/112 (47%), Gaps = 15/112 (13%)
Query: 55 NGYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVEV-EDI 113
+G + SP +P YP +L TW + +Q F + F LE+ +D++ + E+
Sbjct: 1035 SGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNF-HTFHLED------HHDYLLITENG 1087
Query: 114 SETSTIIRGRWCGHKEVPPRIKS---RTNQIKITFKSDDYFVAKPGFKIYYS 162
S T + R ++PP I + + ++ F S D+ ++ GF I +S
Sbjct: 1088 SFTQPLAR---LTGSDLPPTINAGLYGNFRAQLRFIS-DFSISYEGFNITFS 1135
Score = 29.6 bits (65), Expect = 4.4
Identities = 25/112 (22%), Positives = 49/112 (43%), Gaps = 8/112 (7%)
Query: 50 IQVKGNGYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVE 109
+++ G + SP +P+SYP + W + ++ I + F F E+ +D ++
Sbjct: 2421 LRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITM-FVEFFQTEK------EFDVLQ 2473
Query: 110 VEDISETSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYY 161
V D + + G I S +++ + + S D+ K GF+I Y
Sbjct: 2474 VYDGPNIQSPVLISLSGDYSSAFNITSNGHEVFLQW-SADHGNNKKGFRIRY 2524
>gi|205277354 CUB and Sushi multiple domains 3 isoform 3 [Homo
sapiens]
Length = 3538
Score = 62.0 bits (149), Expect = 8e-10
Identities = 39/111 (35%), Positives = 57/111 (51%), Gaps = 9/111 (8%)
Query: 55 NGYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVEVEDIS 114
NG ++SP FP YP TW + ++E RIQ+VF + F LEE YD++ + D
Sbjct: 73 NGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQS-FALEE------EYDYLSLYDGH 125
Query: 115 ETSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYYSLLE 165
T R R G +PP + S + + S D+ V+ GFK+YY L+
Sbjct: 126 PHPTNFRTRLTGF-HLPPPVTSTKSVFSLRLTS-DFAVSAHGFKVYYEELQ 174
Score = 53.1 bits (126), Expect = 4e-07
Identities = 32/94 (34%), Positives = 48/94 (51%), Gaps = 12/94 (12%)
Query: 55 NGYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVEVEDIS 114
+G + SP FPN Y N TW + ++ I L+F F +EE +YD++E+E S
Sbjct: 249 SGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIF-TDFQMEE------KYDYLEIEG-S 300
Query: 115 ETSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSD 148
E TI W +PP I S N +++ F +D
Sbjct: 301 EPPTI----WLSGMNIPPPIISNKNWLRLHFVTD 330
Score = 50.1 bits (118), Expect = 3e-06
Identities = 39/108 (36%), Positives = 56/108 (51%), Gaps = 11/108 (10%)
Query: 55 NGYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVEVED-I 113
+G + SP FP +YP +L TW ++ + L F N F E +D++EV
Sbjct: 2015 SGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVN-FSTETI------HDYLEVRSGS 2067
Query: 114 SETSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYY 161
SETST+I GR G ++P + S T++ + F S DY K GF I Y
Sbjct: 2068 SETSTVI-GRLSG-PQIPSSLFSTTHETSLYFHS-DYSQNKQGFHIVY 2112
Score = 45.4 bits (106), Expect = 8e-05
Identities = 31/107 (28%), Positives = 56/107 (52%), Gaps = 9/107 (8%)
Query: 55 NGYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVEVEDIS 114
+G++ SP FP+ YP + W + + I L F + F +E YDF+ + D
Sbjct: 1492 SGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFIS-FSIEP------NYDFLYIYDGP 1544
Query: 115 ETSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYY 161
++++ + G + K +P RI+S +N + + F+SD V+ GF + Y
Sbjct: 1545 DSNSPLIGSFQDSK-LPERIESSSNTMHLAFRSDG-SVSYTGFHLEY 1589
Score = 34.7 bits (78), Expect = 0.14
Identities = 31/113 (27%), Positives = 49/113 (43%), Gaps = 15/113 (13%)
Query: 53 KGNGYVQSPRFPNSYPRNLLLTWRLHSQENTRIQL---VFDNQFGLEEAENDICRYDFVE 109
+ +G + SP +P Y NL W + + L FD EA +DI R
Sbjct: 1317 ESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDT-----EASHDILR----- 1366
Query: 110 VEDISETSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYYS 162
V D + ++ G +P I S N + I F +D ++++K GF I +S
Sbjct: 1367 VWDGPPENDMLLKEISGSL-IPEGIHSTLNIVTIQFDTD-FYISKSGFAIQFS 1417
Score = 31.6 bits (70), Expect = 1.2
Identities = 26/94 (27%), Positives = 43/94 (45%), Gaps = 8/94 (8%)
Query: 55 NGYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVEVEDIS 114
NG + SP +P+ YP W + I + F + + E YDF+ V D
Sbjct: 2187 NGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYI----NFTVLQTEP---IYDFITVWDGP 2239
Query: 115 ETSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSD 148
+ ++ G++ G+ + + S +NQI I F SD
Sbjct: 2240 DQNSPQIGQFSGNTAL-ESVYSTSNQILIKFHSD 2272
Score = 30.0 bits (66), Expect = 3.4
Identities = 29/112 (25%), Positives = 53/112 (47%), Gaps = 15/112 (13%)
Query: 55 NGYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVEV-EDI 113
+G + SP +P YP +L TW + +Q F + F LE+ +D++ + E+
Sbjct: 971 SGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNF-HTFHLED------HHDYLLITENG 1023
Query: 114 SETSTIIRGRWCGHKEVPPRIKS---RTNQIKITFKSDDYFVAKPGFKIYYS 162
S T + R ++PP I + + ++ F S D+ ++ GF I +S
Sbjct: 1024 SFTQPLAR---LTGSDLPPTINAGLYGNFRAQLRFIS-DFSISYEGFNITFS 1071
Score = 29.6 bits (65), Expect = 4.4
Identities = 25/112 (22%), Positives = 49/112 (43%), Gaps = 8/112 (7%)
Query: 50 IQVKGNGYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVE 109
+++ G + SP +P+SYP + W + ++ I + F F E+ +D ++
Sbjct: 2357 LRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITM-FVEFFQTEK------EFDVLQ 2409
Query: 110 VEDISETSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYY 161
V D + + G I S +++ + + S D+ K GF+I Y
Sbjct: 2410 VYDGPNIQSPVLISLSGDYSSAFNITSNGHEVFLQW-SADHGNNKKGFRIRY 2460
>gi|38045888 CUB and Sushi multiple domains 3 isoform 1 [Homo
sapiens]
Length = 3707
Score = 62.0 bits (149), Expect = 8e-10
Identities = 39/111 (35%), Positives = 57/111 (51%), Gaps = 9/111 (8%)
Query: 55 NGYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVEVEDIS 114
NG ++SP FP YP TW + ++E RIQ+VF + F LEE YD++ + D
Sbjct: 73 NGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQS-FALEE------EYDYLSLYDGH 125
Query: 115 ETSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYYSLLE 165
T R R G +PP + S + + S D+ V+ GFK+YY L+
Sbjct: 126 PHPTNFRTRLTGF-HLPPPVTSTKSVFSLRLTS-DFAVSAHGFKVYYEELQ 174
Score = 53.1 bits (126), Expect = 4e-07
Identities = 32/94 (34%), Positives = 48/94 (51%), Gaps = 12/94 (12%)
Query: 55 NGYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVEVEDIS 114
+G + SP FPN Y N TW + ++ I L+F F +EE +YD++E+E S
Sbjct: 249 SGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIF-TDFQMEE------KYDYLEIEG-S 300
Query: 115 ETSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSD 148
E TI W +PP I S N +++ F +D
Sbjct: 301 EPPTI----WLSGMNIPPPIISNKNWLRLHFVTD 330
Score = 50.1 bits (118), Expect = 3e-06
Identities = 39/108 (36%), Positives = 56/108 (51%), Gaps = 11/108 (10%)
Query: 55 NGYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVEVED-I 113
+G + SP FP +YP +L TW ++ + L F N F E +D++EV
Sbjct: 2119 SGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVN-FSTETI------HDYLEVRSGS 2171
Query: 114 SETSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYY 161
SETST+I GR G ++P + S T++ + F S DY K GF I Y
Sbjct: 2172 SETSTVI-GRLSG-PQIPSSLFSTTHETSLYFHS-DYSQNKQGFHIVY 2216
Score = 45.4 bits (106), Expect = 8e-05
Identities = 31/107 (28%), Positives = 56/107 (52%), Gaps = 9/107 (8%)
Query: 55 NGYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVEVEDIS 114
+G++ SP FP+ YP + W + + I L F + F +E YDF+ + D
Sbjct: 1596 SGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFIS-FSIEP------NYDFLYIYDGP 1648
Query: 115 ETSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYY 161
++++ + G + K +P RI+S +N + + F+SD V+ GF + Y
Sbjct: 1649 DSNSPLIGSFQDSK-LPERIESSSNTMHLAFRSDG-SVSYTGFHLEY 1693
Score = 34.7 bits (78), Expect = 0.14
Identities = 31/113 (27%), Positives = 49/113 (43%), Gaps = 15/113 (13%)
Query: 53 KGNGYVQSPRFPNSYPRNLLLTWRLHSQENTRIQL---VFDNQFGLEEAENDICRYDFVE 109
+ +G + SP +P Y NL W + + L FD EA +DI R
Sbjct: 1421 ESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDT-----EASHDILR----- 1470
Query: 110 VEDISETSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYYS 162
V D + ++ G +P I S N + I F +D ++++K GF I +S
Sbjct: 1471 VWDGPPENDMLLKEISGSL-IPEGIHSTLNIVTIQFDTD-FYISKSGFAIQFS 1521
Score = 31.6 bits (70), Expect = 1.2
Identities = 26/94 (27%), Positives = 43/94 (45%), Gaps = 8/94 (8%)
Query: 55 NGYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVEVEDIS 114
NG + SP +P+ YP W + I + F + + E YDF+ V D
Sbjct: 2291 NGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYI----NFTVLQTEP---IYDFITVWDGP 2343
Query: 115 ETSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSD 148
+ ++ G++ G+ + + S +NQI I F SD
Sbjct: 2344 DQNSPQIGQFSGNTAL-ESVYSTSNQILIKFHSD 2376
Score = 30.0 bits (66), Expect = 3.4
Identities = 29/112 (25%), Positives = 53/112 (47%), Gaps = 15/112 (13%)
Query: 55 NGYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVEV-EDI 113
+G + SP +P YP +L TW + +Q F + F LE+ +D++ + E+
Sbjct: 1075 SGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNF-HTFHLED------HHDYLLITENG 1127
Query: 114 SETSTIIRGRWCGHKEVPPRIKS---RTNQIKITFKSDDYFVAKPGFKIYYS 162
S T + R ++PP I + + ++ F S D+ ++ GF I +S
Sbjct: 1128 SFTQPLAR---LTGSDLPPTINAGLYGNFRAQLRFIS-DFSISYEGFNITFS 1175
Score = 29.6 bits (65), Expect = 4.4
Identities = 25/112 (22%), Positives = 49/112 (43%), Gaps = 8/112 (7%)
Query: 50 IQVKGNGYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVE 109
+++ G + SP +P+SYP + W + ++ I + F F E+ +D ++
Sbjct: 2461 LRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITM-FVEFFQTEK------EFDVLQ 2513
Query: 110 VEDISETSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYY 161
V D + + G I S +++ + + S D+ K GF+I Y
Sbjct: 2514 VYDGPNIQSPVLISLSGDYSSAFNITSNGHEVFLQW-SADHGNNKKGFRIRY 2564
>gi|24041026 neuropilin- and tolloid-like protein 2 precursor [Homo
sapiens]
Length = 525
Score = 60.8 bits (146), Expect = 2e-09
Identities = 38/117 (32%), Positives = 59/117 (50%), Gaps = 4/117 (3%)
Query: 50 IQVKGNGYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVE 109
++ G+ SP +P+SYP N + L + RI+L FD + +E + CR+D +E
Sbjct: 49 VRTSNGGHFASPNYPDSYPPNKECIYILEAAPRQRIELTFDEHYYIEPSFE--CRFDHLE 106
Query: 110 VEDISETSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYYSLLED 166
V D + + R+CG K PP I+S + I F SD+ GF+ YS + D
Sbjct: 107 VRDGPFGFSPLIDRYCGVKS-PPLIRSTGRFMWIKFSSDEELEGL-GFRAKYSFIPD 161
>gi|21264363 mannan-binding lectin serine protease 2 isoform 1
precursor [Homo sapiens]
Length = 686
Score = 57.8 bits (138), Expect = 2e-08
Identities = 33/108 (30%), Positives = 59/108 (54%), Gaps = 6/108 (5%)
Query: 55 NGYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVEVEDIS 114
+G + SP +P YP+ T+ + +E + L F F +E +C YDF++++
Sbjct: 193 SGELSSPEYPRPYPKLSSCTYSISLEEGFSVILDFVESFDVETHPETLCPYDFLKIQTDR 252
Query: 115 ETSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYYS 162
E G +CG K +P RI++++N + ITF +D+ G+KI+Y+
Sbjct: 253 EE----HGPFCG-KTLPHRIETKSNTVTITFVTDE-SGDHTGWKIHYT 294
Score = 42.4 bits (98), Expect = 7e-04
Identities = 34/112 (30%), Positives = 53/112 (47%), Gaps = 9/112 (8%)
Query: 56 GYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVEVEDISE 115
G + SP FP Y + W L + R++L F F LE + +C YDFV++ ++
Sbjct: 28 GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYF-THFDLELSH--LCEYDFVKLSSGAK 84
Query: 116 TSTIIRGRWCGHKEVPP---RIKSRTNQIKITFKSDDYFVAKP--GFKIYYS 162
+ G+ E P S + + ITF+S DY KP GF+ +Y+
Sbjct: 85 VLATLCGQESTDTERAPGKDTFYSLGSSLDITFRS-DYSNEKPFTGFEAFYA 135
>gi|13899255 membrane frizzled-related protein [Homo sapiens]
Length = 579
Score = 57.8 bits (138), Expect = 2e-08
Identities = 35/107 (32%), Positives = 56/107 (52%), Gaps = 6/107 (5%)
Query: 56 GYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVEVEDISE 115
G +P + YP LL TW + I+L F N F LE D C++D+VEV + S
Sbjct: 310 GTFSTPSYLQQYPHQLLCTWHISVPAGHSIELQFHN-FSLE--AQDECKFDYVEVYETSS 366
Query: 116 TSTI-IRGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYY 161
+ + GR+CG E PP + S +++ + F++ D+ ++ GF Y
Sbjct: 367 SGAFSLLGRFCG-AEPPPHLVSSHHELAVLFRT-DHGISSGGFSATY 411
Score = 38.1 bits (87), Expect = 0.012
Identities = 28/109 (25%), Positives = 48/109 (44%), Gaps = 8/109 (7%)
Query: 56 GYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVEVEDISE 115
G+ SP +P+ YP N W + + IQL + +E + C +D +E+ E
Sbjct: 153 GFFSSPNYPDPYPPNTHCVWHIQVATDHAIQLKIE-ALSIESVAS--CLFDRLELSPEPE 209
Query: 116 TSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYYSLL 164
+ R CG + PP + + + + + F SD V GF +Y +
Sbjct: 210 GPLL---RVCG-RVPPPTLNTNASHLLVVFVSDS-SVEGFGFHAWYQAM 253
>gi|92110053 CUB and Sushi multiple domains 2 [Homo sapiens]
Length = 3487
Score = 53.9 bits (128), Expect = 2e-07
Identities = 42/117 (35%), Positives = 57/117 (48%), Gaps = 10/117 (8%)
Query: 49 TIQVKG-NGYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDF 107
T Q+ G NG V+SP FP YP TW + ++E RIQLVF + F LEE +D
Sbjct: 27 TFQLHGPNGTVESPGFPYGYPNYANCTWTITAEEQHRIQLVFQS-FALEE------DFDV 79
Query: 108 VEVEDISETSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYYSLL 164
+ V D +R R G ++P I S + + S DY V+ GF Y +L
Sbjct: 80 LSVFDGPPQPENLRTRLTGF-QLPATIVSAATTLSLRLIS-DYAVSAQGFHATYEVL 134
Score = 48.5 bits (114), Expect = 9e-06
Identities = 34/108 (31%), Positives = 56/108 (51%), Gaps = 9/108 (8%)
Query: 55 NGYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVEVEDIS 114
+G + SP +P YP W++ + I LVF N F LE YDF+ + D
Sbjct: 1453 SGVILSPNYPEPYPPGKECDWKVTVSPDYVIALVF-NIFNLEPG------YDFLHIYDGR 1505
Query: 115 ETSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYYS 162
++ + + G + G ++P RI+S +N + + F+S D V+ GF I Y+
Sbjct: 1506 DSLSPLIGSFYG-SQLPGRIESSSNSLFLAFRS-DASVSNAGFVIDYT 1551
Score = 45.1 bits (105), Expect = 1e-04
Identities = 29/106 (27%), Positives = 54/106 (50%), Gaps = 9/106 (8%)
Query: 56 GYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVEVEDISE 115
G + SP FP +YP N+ +W++ + F N F E +D++E+ +
Sbjct: 1977 GVILSPGFPGNYPSNMDCSWKIALPVGFGAHIQFLN-FSTEP------NHDYIEIRNGPY 2029
Query: 116 TSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYY 161
++ + GR+ G E+P + S +++ + F S D+ +PGFK+ Y
Sbjct: 2030 ETSRMMGRFSG-SELPSSLLSTSHETTVYFHS-DHSQNRPGFKLEY 2073
Score = 43.1 bits (100), Expect = 4e-04
Identities = 33/114 (28%), Positives = 51/114 (44%), Gaps = 13/114 (11%)
Query: 55 NGYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVEVEDIS 114
+G + SP FP+ Y N TW + ++ I LVF + F LE+ YDF+EV
Sbjct: 210 SGIISSPHFPSEYHNNADCTWTILAELGDTIALVFID-FQLEDG------YDFLEV---- 258
Query: 115 ETSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYYSLLEDFQ 168
T T W +P + S N +++ F SD + GF Y + + +
Sbjct: 259 -TGTEGSSLWFTGASLPAPVISSKNWLRLHFTSDGNH-RQRGFSAQYQVKKQIE 310
Score = 43.1 bits (100), Expect = 4e-04
Identities = 28/108 (25%), Positives = 55/108 (50%), Gaps = 9/108 (8%)
Query: 55 NGYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVEVEDIS 114
+G V SP +P Y +L W + ++ +RI L F N +E ++DF+ ++D +
Sbjct: 586 SGVVLSPNYPEDYGNHLHCVWLILARPESRIHLAF-NDIDVEP------QFDFLVIKDGA 638
Query: 115 ETSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYYS 162
+ G + G+ ++P I S + ++ F++ D+ K GF I ++
Sbjct: 639 TAEAPVLGTFSGN-QLPSSITSSGHVARLEFQT-DHSTGKRGFNITFT 684
Score = 40.0 bits (92), Expect = 0.003
Identities = 32/115 (27%), Positives = 53/115 (46%), Gaps = 9/115 (7%)
Query: 49 TIQVKGNGYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFV 108
T++ + +G V SP +P Y NL W + ++ I L F F EE +D +
Sbjct: 1274 TVRGEVSGQVLSPGYPAPYEHNLNCIWTIEAEAGCTIGLHF-LVFDTEEV------HDVL 1326
Query: 109 EVEDISETSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYYSL 163
+ D S ++ G +P + S N + + F S D+F +K GF I +S+
Sbjct: 1327 RIWDGPVESGVLLKELSG-PALPKDLHSTFNSVVLQF-STDFFTSKQGFAIQFSV 1379
Score = 38.5 bits (88), Expect = 0.010
Identities = 31/106 (29%), Positives = 51/106 (48%), Gaps = 9/106 (8%)
Query: 56 GYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVEVEDISE 115
G + SP FP Y +L W++ E IQ+ + F E+ +D +EV D ++
Sbjct: 1805 GTILSPGFPEPYLNSLNCVWKIVVPEGAGIQIQVVS-FVTEQ------NWDSLEVFDGAD 1857
Query: 116 TSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYY 161
+ + G + G VP + S +NQ+ + F S D V+ GF + Y
Sbjct: 1858 NTVTMLGSFSG-TTVPALLNSTSNQLYLHFYS-DISVSAAGFHLEY 1901
Score = 37.0 bits (84), Expect = 0.028
Identities = 28/107 (26%), Positives = 48/107 (44%), Gaps = 8/107 (7%)
Query: 56 GYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVEVEDISE 115
G + S +P SYP+ +W + + + I L ++ L E + YD E+ D
Sbjct: 2366 GVILSQSYPGSYPQFQTCSWLVRVEPDYNISLTV--EYFLSEKQ-----YDEFEIFDGPS 2418
Query: 116 TSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYYS 162
+ + G+ P + S +N + + + SD + K GFKI YS
Sbjct: 2419 GQSPLLKALSGNYSAPLIVTSSSNSVYLRWSSDHAYNRK-GFKIRYS 2464
Score = 30.8 bits (68), Expect = 2.0
Identities = 15/46 (32%), Positives = 23/46 (50%), Gaps = 1/46 (2%)
Query: 55 NGYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAEN 100
+G + SP FP+ YP NL TW + + + F + F LE +
Sbjct: 932 SGTILSPGFPDFYPNNLNCTWIIETSHGKGVFFTF-HTFHLESGHD 976
Score = 28.9 bits (63), Expect = 7.6
Identities = 27/110 (24%), Positives = 50/110 (45%), Gaps = 9/110 (8%)
Query: 56 GYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVEVEDISE 115
G + SP FP +Y N + + +Q IQL F L E D ++V D +
Sbjct: 1107 GTLLSPNFPVNYNNNHECIYSIQTQPGKGIQLK-ARAFELSEG-------DVLKVYDGNN 1158
Query: 116 TSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYYSLLE 165
S + G + + + + S ++ + + F +D +K GF++++S E
Sbjct: 1159 NSARLLGVFSHSEMMGVTLNSTSSSLWLDFITDAENTSK-GFELHFSSFE 1207
>gi|157502199 CUB and Sushi multiple domains 1 [Homo sapiens]
Length = 3565
Score = 53.5 bits (127), Expect = 3e-07
Identities = 32/108 (29%), Positives = 58/108 (53%), Gaps = 9/108 (8%)
Query: 55 NGYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVEVEDIS 114
+G + SP +P Y N+ W + S+ +RI L+F N F +E ++DF+ V+D
Sbjct: 593 SGIILSPNYPEEYGNNMNCVWLIISEPGSRIHLIF-NDFDVEP------QFDFLAVKDDG 645
Query: 115 ETSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYYS 162
+ + G + G+ EVP ++ S + +++ F+SD + GF I Y+
Sbjct: 646 ISDITVLGTFSGN-EVPSQLASSGHIVRLEFQSDHSTTGR-GFNITYT 691
Score = 49.7 bits (117), Expect = 4e-06
Identities = 37/110 (33%), Positives = 54/110 (49%), Gaps = 9/110 (8%)
Query: 55 NGYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVEVEDIS 114
NG ++SP FP+ YP TW + + E RIQL F + F LEE +D + V D
Sbjct: 40 NGTIESPGFPHGYPNYANCTWIIITGERNRIQLSF-HTFALEE------DFDILSVYDGQ 92
Query: 115 ETSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYYSLL 164
++ R G ++P I S T I + + D+ V+ GFK Y +L
Sbjct: 93 PQQGNLKVRLSGF-QLPSSIVS-TGSILTLWFTTDFAVSAQGFKALYEVL 140
Score = 48.9 bits (115), Expect = 7e-06
Identities = 35/116 (30%), Positives = 52/116 (44%), Gaps = 15/116 (12%)
Query: 50 IQVKGNGYVQSPRFPNSYPRNLLLTWRLHSQENTRIQL---VFDNQFGLEEAENDICRYD 106
I +G + SP +P Y NL TW + + I L VFD + +D
Sbjct: 1282 IHAATSGRILSPGYPAPYDNNLHCTWIIEADPGKTISLHFIVFDTEMA----------HD 1331
Query: 107 FVEVEDISETSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYYS 162
++V D S I+ W G +P I S N + + F SD +F++K GF I +S
Sbjct: 1332 ILKVWDGPVDSDILLKEWSG-SALPEDIHSTFNSLTLQFDSD-FFISKSGFSIQFS 1385
Score = 46.6 bits (109), Expect = 4e-05
Identities = 34/110 (30%), Positives = 55/110 (50%), Gaps = 9/110 (8%)
Query: 56 GYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVEVEDISE 115
G + SP FP SYP NL TWR+ + F N F E +DF+E+++
Sbjct: 1984 GVILSPGFPGSYPNNLDCTWRISLPIGYGAHIQFLN-FSTE------ANHDFLEIQNGPY 2036
Query: 116 TSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYYSLLE 165
++ + G++ G ++P + S T++ I F S D+ + GFK+ Y E
Sbjct: 2037 HTSPMIGQFSG-TDLPAALLSTTHETLIHFYS-DHSQNRQGFKLAYQAYE 2084
Score = 44.3 bits (103), Expect = 2e-04
Identities = 30/106 (28%), Positives = 52/106 (49%), Gaps = 9/106 (8%)
Query: 56 GYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVEVEDISE 115
G + SP +P YP WR+ + I L+F F +E + YDF+ + + +
Sbjct: 1461 GVILSPNYPQPYPPGKECDWRVKVNPDFVIALIF-KSFNMEPS------YDFLHIYEGED 1513
Query: 116 TSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYY 161
+++ + G + G + P RI+S N + + F+S D V GF I +
Sbjct: 1514 SNSPLIGSYQG-SQAPERIESSGNSLFLAFRS-DASVGLSGFAIEF 1557
Score = 43.1 bits (100), Expect = 4e-04
Identities = 28/91 (30%), Positives = 40/91 (43%), Gaps = 12/91 (13%)
Query: 58 VQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVEVEDISETS 117
+ SP FP+ Y N TW + ++ I LVF F LEE YDF+E+ S
Sbjct: 219 ISSPHFPSEYENNADCTWTILAEPGDTIALVF-TDFQLEEG------YDFLEISGTEAPS 271
Query: 118 TIIRGRWCGHKEVPPRIKSRTNQIKITFKSD 148
W +P + S N +++ F SD
Sbjct: 272 I-----WLTGMNLPSPVISSKNWLRLHFTSD 297
Score = 41.2 bits (95), Expect = 0.001
Identities = 31/106 (29%), Positives = 51/106 (48%), Gaps = 9/106 (8%)
Query: 56 GYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVEVEDISE 115
G + SP +P Y NL W++ E + IQ+ + F E+ +D +E+ D +
Sbjct: 1812 GTILSPGYPEPYGNNLNCIWKIIVTEGSGIQIQVIS-FATEQ------NWDSLEIHDGGD 1864
Query: 116 TSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYY 161
+ G + G VP + S +NQ+ + F+S D VA GF + Y
Sbjct: 1865 VTAPRLGSFSG-TTVPALLNSTSNQLYLHFQS-DISVAAAGFHLEY 1908
Score = 36.6 bits (83), Expect = 0.036
Identities = 28/108 (25%), Positives = 47/108 (43%), Gaps = 7/108 (6%)
Query: 55 NGYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVEVEDIS 114
+G V SP FP+ YP +L TW + +Q++F + F LE + + + E S
Sbjct: 939 SGTVLSPGFPDFYPNSLNCTWTIEVSHGKGVQMIF-HTFHLESSHDYLL---ITEDGSFS 994
Query: 115 ETSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYYS 162
E + G H + T Q++ D+ ++ GF I +S
Sbjct: 995 EPVARLTGSVLPHTIKAGLFGNFTAQLRFI---SDFSISYEGFNITFS 1039
>gi|72384339 CUB domain containing protein 2 [Homo sapiens]
Length = 449
Score = 53.1 bits (126), Expect = 4e-07
Identities = 31/107 (28%), Positives = 54/107 (50%), Gaps = 7/107 (6%)
Query: 55 NGYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVEVEDIS 114
+G + SP +PN+YP ++ W + + ++LVF + N+ C YD+V V +
Sbjct: 153 SGVLTSPEYPNNYPNSMECHWVIRAAGPAHVKLVF---VDFQVEGNEECTYDYVAV--LG 207
Query: 115 ETSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYY 161
+CG PP + S +++++ FKS D+ + GFK YY
Sbjct: 208 GPGPTRGHHYCGSTR-PPTLVSLGHELQVVFKS-DFNIGGRGFKAYY 252
Score = 52.8 bits (125), Expect = 5e-07
Identities = 31/108 (28%), Positives = 51/108 (47%), Gaps = 5/108 (4%)
Query: 56 GYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAEN--DICRYDFVEVEDI 113
G SP++P+SYP N+ W + +++ VF LEE + C +D + D
Sbjct: 266 GNFSSPQYPSSYPNNIRCHWTIRLPPGYQVK-VFFLDLDLEEPNSLTKTCDFDHLAAFDG 324
Query: 114 SETSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYY 161
+ + G WCGH +PP + S NQ+ + + D + GF + Y
Sbjct: 325 ASEEAPLLGNWCGH-HLPPPVTSSHNQLLLLLHT-DRSTTRRGFSVAY 370
Score = 52.4 bits (124), Expect = 6e-07
Identities = 37/108 (34%), Positives = 53/108 (49%), Gaps = 6/108 (5%)
Query: 55 NGYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVEV-EDI 113
+G SP FP YP N +W + E + + L F + F LE +D C +DF+E+
Sbjct: 38 SGNFSSPNFPRLYPYNTECSWLIVVAEGSSVLLTF-HAFDLE--YHDTCSFDFLEIYNGA 94
Query: 114 SETSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYY 161
S + GR+CG K PP S + + + F SD + VA GF Y
Sbjct: 95 SPDKGNLLGRFCG-KVPPPPFTSSWHVMSVIFHSDKH-VASHGFSAGY 140
>gi|73623026 mannan-binding lectin serine protease 1 isoform 3 [Homo
sapiens]
Length = 380
Score = 52.0 bits (123), Expect = 8e-07
Identities = 26/94 (27%), Positives = 50/94 (53%), Gaps = 5/94 (5%)
Query: 56 GYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVEVEDISE 115
G + SP FPN YP++ + + +E + L F++ F +E+ C YD++++ +
Sbjct: 195 GVITSPDFPNPYPKSSECLYTIELEEGFMVNLQFEDIFDIEDHPEVPCPYDYIKI----K 250
Query: 116 TSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDD 149
+ G +CG K P I ++++ + I F SD+
Sbjct: 251 VGPKVLGPFCGEK-APEPISTQSHSVLILFHSDN 283
Score = 51.6 bits (122), Expect = 1e-06
Identities = 33/96 (34%), Positives = 50/96 (52%), Gaps = 6/96 (6%)
Query: 56 GYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVEVEDISE 115
G +QSP +P+SYP + +TW + + RI+L F F LE + +C YD+V+VE +
Sbjct: 29 GQIQSPGYPDSYPSDSEVTWNITVPDGFRIKLYF-MHFNLESSY--LCEYDYVKVETEDQ 85
Query: 116 TSTIIRGRWCGHKEVPPR---IKSRTNQIKITFKSD 148
GR E P + S + + ITF+SD
Sbjct: 86 VLATFCGRETTDTEQTPGQEVVLSPGSFMSITFRSD 121
>gi|21264359 mannan-binding lectin serine protease 1 isoform 2
precursor [Homo sapiens]
Length = 728
Score = 52.0 bits (123), Expect = 8e-07
Identities = 26/94 (27%), Positives = 50/94 (53%), Gaps = 5/94 (5%)
Query: 56 GYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVEVEDISE 115
G + SP FPN YP++ + + +E + L F++ F +E+ C YD++++ +
Sbjct: 195 GVITSPDFPNPYPKSSECLYTIELEEGFMVNLQFEDIFDIEDHPEVPCPYDYIKI----K 250
Query: 116 TSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDD 149
+ G +CG K P I ++++ + I F SD+
Sbjct: 251 VGPKVLGPFCGEK-APEPISTQSHSVLILFHSDN 283
Score = 51.6 bits (122), Expect = 1e-06
Identities = 33/96 (34%), Positives = 50/96 (52%), Gaps = 6/96 (6%)
Query: 56 GYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVEVEDISE 115
G +QSP +P+SYP + +TW + + RI+L F F LE + +C YD+V+VE +
Sbjct: 29 GQIQSPGYPDSYPSDSEVTWNITVPDGFRIKLYF-MHFNLESSY--LCEYDYVKVETEDQ 85
Query: 116 TSTIIRGRWCGHKEVPPR---IKSRTNQIKITFKSD 148
GR E P + S + + ITF+SD
Sbjct: 86 VLATFCGRETTDTEQTPGQEVVLSPGSFMSITFRSD 121
>gi|21264357 mannan-binding lectin serine protease 1 isoform 1
precursor [Homo sapiens]
Length = 699
Score = 52.0 bits (123), Expect = 8e-07
Identities = 26/94 (27%), Positives = 50/94 (53%), Gaps = 5/94 (5%)
Query: 56 GYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVEVEDISE 115
G + SP FPN YP++ + + +E + L F++ F +E+ C YD++++ +
Sbjct: 195 GVITSPDFPNPYPKSSECLYTIELEEGFMVNLQFEDIFDIEDHPEVPCPYDYIKI----K 250
Query: 116 TSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDD 149
+ G +CG K P I ++++ + I F SD+
Sbjct: 251 VGPKVLGPFCGEK-APEPISTQSHSVLILFHSDN 283
Score = 51.6 bits (122), Expect = 1e-06
Identities = 33/96 (34%), Positives = 50/96 (52%), Gaps = 6/96 (6%)
Query: 56 GYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVEVEDISE 115
G +QSP +P+SYP + +TW + + RI+L F F LE + +C YD+V+VE +
Sbjct: 29 GQIQSPGYPDSYPSDSEVTWNITVPDGFRIKLYF-MHFNLESSY--LCEYDYVKVETEDQ 85
Query: 116 TSTIIRGRWCGHKEVPPR---IKSRTNQIKITFKSD 148
GR E P + S + + ITF+SD
Sbjct: 86 VLATFCGRETTDTEQTPGQEVVLSPGSFMSITFRSD 121
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.136 0.423
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,869,322
Number of Sequences: 37866
Number of extensions: 641056
Number of successful extensions: 1847
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 51
Number of HSP's successfully gapped in prelim test: 32
Number of HSP's that attempted gapping in prelim test: 1604
Number of HSP's gapped (non-prelim): 190
length of query: 364
length of database: 18,247,518
effective HSP length: 104
effective length of query: 260
effective length of database: 14,309,454
effective search space: 3720458040
effective search space used: 3720458040
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.