Guide to the Human Genome
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Search of human proteins with 154275771

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|154275771 RAD51 homolog protein isoform 2 [Homo sapiens]
         (242 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|154275771 RAD51 homolog protein isoform 2 [Homo sapiens]           472   e-133
gi|19924133 RAD51 homolog protein isoform 1 [Homo sapiens]            329   2e-90
gi|23238219 DMC1 dosage suppressor of mck1 homolog [Homo sapiens]     184   8e-47
gi|46255039 RAD51-like 1 isoform 3 [Homo sapiens]                      58   8e-09
gi|19924117 RAD51-like 1 isoform 2 [Homo sapiens]                      58   8e-09
gi|10835029 RAD51-like 1 isoform 1 [Homo sapiens]                      58   8e-09
gi|17402896 RAD51 homolog C isoform 1 [Homo sapiens]                   50   2e-06
gi|19924125 RAD51-like 3 isoform 4 [Homo sapiens]                      37   0.020
gi|217272816 RAD51-like 3 isoform 6 [Homo sapiens]                     34   0.13 
gi|217416415 RAD51-like 3 isoform 1 [Homo sapiens]                     34   0.13 
gi|4885657 X-ray repair cross complementing protein 2 [Homo sapi...    28   5.5  
gi|119392094 immunoglobulin mu binding protein 2 [Homo sapiens]        28   7.2  
gi|153791514 tripartite motif-containing 32 [Homo sapiens]             28   7.2  
gi|153792582 tripartite motif-containing 32 [Homo sapiens]             28   7.2  
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]    28   9.4  

>gi|154275771 RAD51 homolog protein isoform 2 [Homo sapiens]
          Length = 242

 Score =  472 bits (1214), Expect = e-133
 Identities = 242/242 (100%), Positives = 242/242 (100%)

Query: 1   MAMQMQLEANADTSVEEESFGPQPISRLEQCGINANDVKKLEEAGFHTVEAVAYAPKKEL 60
           MAMQMQLEANADTSVEEESFGPQPISRLEQCGINANDVKKLEEAGFHTVEAVAYAPKKEL
Sbjct: 1   MAMQMQLEANADTSVEEESFGPQPISRLEQCGINANDVKKLEEAGFHTVEAVAYAPKKEL 60

Query: 61  INIKGISEAKADKILVMAERYGLSGSDVLDNVAYARAFNTDHQTQLLYQASAMMVESRYA 120
           INIKGISEAKADKILVMAERYGLSGSDVLDNVAYARAFNTDHQTQLLYQASAMMVESRYA
Sbjct: 61  INIKGISEAKADKILVMAERYGLSGSDVLDNVAYARAFNTDHQTQLLYQASAMMVESRYA 120

Query: 121 LLIVDSATALYRTDYSGRGELSARQMHLARFLRMLLRLADEFGVAVVITNQVVAQVDGAA 180
           LLIVDSATALYRTDYSGRGELSARQMHLARFLRMLLRLADEFGVAVVITNQVVAQVDGAA
Sbjct: 121 LLIVDSATALYRTDYSGRGELSARQMHLARFLRMLLRLADEFGVAVVITNQVVAQVDGAA 180

Query: 181 MFAADPKKPIGGNIIAHASTTRLYLRKGRGETRICKIYDSPCLPEAEAMFAINADGVGDA 240
           MFAADPKKPIGGNIIAHASTTRLYLRKGRGETRICKIYDSPCLPEAEAMFAINADGVGDA
Sbjct: 181 MFAADPKKPIGGNIIAHASTTRLYLRKGRGETRICKIYDSPCLPEAEAMFAINADGVGDA 240

Query: 241 KD 242
           KD
Sbjct: 241 KD 242


>gi|19924133 RAD51 homolog protein isoform 1 [Homo sapiens]
          Length = 339

 Score =  329 bits (843), Expect = 2e-90
 Identities = 166/173 (95%), Positives = 171/173 (98%)

Query: 70  KADKILVMAERYGLSGSDVLDNVAYARAFNTDHQTQLLYQASAMMVESRYALLIVDSATA 129
           + +++L +AERYGLSGSDVLDNVAYARAFNTDHQTQLLYQASAMMVESRYALLIVDSATA
Sbjct: 167 RPERLLAVAERYGLSGSDVLDNVAYARAFNTDHQTQLLYQASAMMVESRYALLIVDSATA 226

Query: 130 LYRTDYSGRGELSARQMHLARFLRMLLRLADEFGVAVVITNQVVAQVDGAAMFAADPKKP 189
           LYRTDYSGRGELSARQMHLARFLRMLLRLADEFGVAVVITNQVVAQVDGAAMFAADPKKP
Sbjct: 227 LYRTDYSGRGELSARQMHLARFLRMLLRLADEFGVAVVITNQVVAQVDGAAMFAADPKKP 286

Query: 190 IGGNIIAHASTTRLYLRKGRGETRICKIYDSPCLPEAEAMFAINADGVGDAKD 242
           IGGNIIAHASTTRLYLRKGRGETRICKIYDSPCLPEAEAMFAINADGVGDAKD
Sbjct: 287 IGGNIIAHASTTRLYLRKGRGETRICKIYDSPCLPEAEAMFAINADGVGDAKD 339



 Score =  149 bits (377), Expect = 2e-36
 Identities = 76/80 (95%), Positives = 77/80 (96%)

Query: 1  MAMQMQLEANADTSVEEESFGPQPISRLEQCGINANDVKKLEEAGFHTVEAVAYAPKKEL 60
          MAMQMQLEANADTSVEEESFGPQPISRLEQCGINANDVKKLEEAGFHTVEAVAYAPKKEL
Sbjct: 1  MAMQMQLEANADTSVEEESFGPQPISRLEQCGINANDVKKLEEAGFHTVEAVAYAPKKEL 60

Query: 61 INIKGISEAKADKILVMAER 80
          INIKGISEAKADKIL  A +
Sbjct: 61 INIKGISEAKADKILAEAAK 80


>gi|23238219 DMC1 dosage suppressor of mck1 homolog [Homo sapiens]
          Length = 340

 Score =  184 bits (466), Expect = 8e-47
 Identities = 96/189 (50%), Positives = 130/189 (68%), Gaps = 2/189 (1%)

Query: 56  PKKELINIKGISEAKADKILVMAERYGLSGSDVLDNVAYARAFNTDHQTQLLYQASAMMV 115
           P  ++I I   +  + D++  +A+R+ +    VLDNV YARA+ ++HQ +LL   +A   
Sbjct: 152 PGGKIIFIDTENTFRPDRLRDIADRFNVDHDAVLDNVLYARAYTSEHQMELLDYVAAKFH 211

Query: 116 ESR--YALLIVDSATALYRTDYSGRGELSARQMHLARFLRMLLRLADEFGVAVVITNQVV 173
           E    + LLI+DS  AL+R D+SGRGEL+ RQ  LA+ L  L ++++E+ VAV +TNQ+ 
Sbjct: 212 EEAGIFKLLIIDSIMALFRVDFSGRGELAERQQKLAQMLSRLQKISEEYNVAVFVTNQMT 271

Query: 174 AQVDGAAMFAADPKKPIGGNIIAHASTTRLYLRKGRGETRICKIYDSPCLPEAEAMFAIN 233
           A       F ADPKKPIGG+I+AHASTTR+ LRKGRGE RI KIYDSP +PE EA FAI 
Sbjct: 272 ADPGATMTFQADPKKPIGGHILAHASTTRISLRKGRGELRIAKIYDSPEMPENEATFAIT 331

Query: 234 ADGVGDAKD 242
           A G+GDAK+
Sbjct: 332 AGGIGDAKE 340



 Score = 53.1 bits (126), Expect = 2e-07
 Identities = 28/65 (43%), Positives = 40/65 (61%), Gaps = 1/65 (1%)

Query: 16 EEESFGPQPISRLEQCGINANDVKKLEEAGFHTVEAVAYAPKKELINIKGISEAKADKIL 75
          EEES   Q I  L++ GIN  D+KKL+  G  T++ +    ++ L N+KG+SEAK DKI 
Sbjct: 16 EEESLF-QDIDLLQKHGINVADIKKLKSVGICTIKGIQMTTRRALCNVKGLSEAKVDKIK 74

Query: 76 VMAER 80
            A +
Sbjct: 75 EAANK 79


>gi|46255039 RAD51-like 1 isoform 3 [Homo sapiens]
          Length = 384

 Score = 57.8 bits (138), Expect = 8e-09
 Identities = 49/192 (25%), Positives = 78/192 (40%), Gaps = 24/192 (12%)

Query: 66  ISEAKADKILVMAERYGLSGSDVLDNVAYARAFNTDHQTQLLYQASAMMVESRYALLIVD 125
           I+E++  +     E+  L+ S     V   R    D   Q +      ++     L+I+D
Sbjct: 155 IAESRFPRYFNTEEKLLLTSS----KVHLYRELTCDEVLQRIESLEEEIISKGIKLVILD 210

Query: 126 SATALYRTDYSGR--GELSARQMHLARFLRMLLRLADEFGVAVVITNQVVAQVDGAAMFA 183
           S  ++ R ++  +  G L  R   LAR    L  LA+EF + V++TNQ+   + GA    
Sbjct: 211 SVASVVRKEFDAQLQGNLKERNKFLAREASSLKYLAEEFSIPVILTNQITTHLSGALASQ 270

Query: 184 ADPKKPIG------------------GNIIAHASTTRLYLRKGRGETRICKIYDSPCLPE 225
           AD   P                    GN  +H+  TRL L+    E R   I  SP  P 
Sbjct: 271 ADLVSPADDLSLSEGTSGSSCVIAALGNTWSHSVNTRLILQYLDSERRQILIAKSPLAPF 330

Query: 226 AEAMFAINADGV 237
              ++ I  +G+
Sbjct: 331 TSFVYTIKEEGL 342


>gi|19924117 RAD51-like 1 isoform 2 [Homo sapiens]
          Length = 350

 Score = 57.8 bits (138), Expect = 8e-09
 Identities = 49/192 (25%), Positives = 78/192 (40%), Gaps = 24/192 (12%)

Query: 66  ISEAKADKILVMAERYGLSGSDVLDNVAYARAFNTDHQTQLLYQASAMMVESRYALLIVD 125
           I+E++  +     E+  L+ S     V   R    D   Q +      ++     L+I+D
Sbjct: 155 IAESRFPRYFNTEEKLLLTSS----KVHLYRELTCDEVLQRIESLEEEIISKGIKLVILD 210

Query: 126 SATALYRTDYSGR--GELSARQMHLARFLRMLLRLADEFGVAVVITNQVVAQVDGAAMFA 183
           S  ++ R ++  +  G L  R   LAR    L  LA+EF + V++TNQ+   + GA    
Sbjct: 211 SVASVVRKEFDAQLQGNLKERNKFLAREASSLKYLAEEFSIPVILTNQITTHLSGALASQ 270

Query: 184 ADPKKPIG------------------GNIIAHASTTRLYLRKGRGETRICKIYDSPCLPE 225
           AD   P                    GN  +H+  TRL L+    E R   I  SP  P 
Sbjct: 271 ADLVSPADDLSLSEGTSGSSCVIAALGNTWSHSVNTRLILQYLDSERRQILIAKSPLAPF 330

Query: 226 AEAMFAINADGV 237
              ++ I  +G+
Sbjct: 331 TSFVYTIKEEGL 342


>gi|10835029 RAD51-like 1 isoform 1 [Homo sapiens]
          Length = 350

 Score = 57.8 bits (138), Expect = 8e-09
 Identities = 49/192 (25%), Positives = 78/192 (40%), Gaps = 24/192 (12%)

Query: 66  ISEAKADKILVMAERYGLSGSDVLDNVAYARAFNTDHQTQLLYQASAMMVESRYALLIVD 125
           I+E++  +     E+  L+ S     V   R    D   Q +      ++     L+I+D
Sbjct: 155 IAESRFPRYFNTEEKLLLTSS----KVHLYRELTCDEVLQRIESLEEEIISKGIKLVILD 210

Query: 126 SATALYRTDYSGR--GELSARQMHLARFLRMLLRLADEFGVAVVITNQVVAQVDGAAMFA 183
           S  ++ R ++  +  G L  R   LAR    L  LA+EF + V++TNQ+   + GA    
Sbjct: 211 SVASVVRKEFDAQLQGNLKERNKFLAREASSLKYLAEEFSIPVILTNQITTHLSGALASQ 270

Query: 184 ADPKKPIG------------------GNIIAHASTTRLYLRKGRGETRICKIYDSPCLPE 225
           AD   P                    GN  +H+  TRL L+    E R   I  SP  P 
Sbjct: 271 ADLVSPADDLSLSEGTSGSSCVIAALGNTWSHSVNTRLILQYLDSERRQILIAKSPLAPF 330

Query: 226 AEAMFAINADGV 237
              ++ I  +G+
Sbjct: 331 TSFVYTIKEEGL 342


>gi|17402896 RAD51 homolog C isoform 1 [Homo sapiens]
          Length = 376

 Score = 50.1 bits (118), Expect = 2e-06
 Identities = 44/156 (28%), Positives = 68/156 (43%), Gaps = 13/156 (8%)

Query: 89  LDNV-AYARAFNTDHQTQLLYQA----SAMMVESRYALLIVDSATALYRTDYSGRGELSA 143
           LDN+ ++   F     T+LL Q       +   S+  L+IVD     +R D     +LS 
Sbjct: 201 LDNILSHIYYFRCRDYTELLAQVYLLPDFLSEHSKVRLVIVDGIAFPFRHDLD---DLSL 257

Query: 144 RQMHLARFLRMLLRLADEFGVAVVITNQVVAQVDGAAMFAADPKKPIGGNIIAHASTTRL 203
           R   L    + ++ LA+   +AV++TNQ+  ++D           P  G    HA+T RL
Sbjct: 258 RTRLLNGLAQQMISLANNHRLAVILTNQMTTKIDRNQALLV----PALGESWGHAATIRL 313

Query: 204 YLRKGRGETRICKIYDSPCLPEAEAMFAINADGVGD 239
                R + R+  +Y SP   E   +F I   G  D
Sbjct: 314 IFHWDR-KQRLATLYKSPSQKECTVLFQIKPQGFRD 348


>gi|19924125 RAD51-like 3 isoform 4 [Homo sapiens]
          Length = 216

 Score = 36.6 bits (83), Expect = 0.020
 Identities = 38/151 (25%), Positives = 67/151 (44%), Gaps = 17/151 (11%)

Query: 63  IKGISEAKADKILVMAERYGLS-GSDVLDNVAYARAFNTDHQTQLLYQASAMMVES---- 117
           IK + +  +  +  +A++ GLS  ++ L  +    AF+      +L +    + +     
Sbjct: 25  IKTVVDLVSADLEEVAQKCGLSYKAEALRRIQVVHAFDIFQMLDVLQELRGTVAQQVTGS 84

Query: 118 --RYALLIVDSATALYRTDYSGRG-ELSARQMHLARFLRMLLRLADEFGVAVVITNQVVA 174
                +++VDS TA+      G+  E  A  M LAR L+ L R   + G+AVV+TN +  
Sbjct: 85  SGTVKVVVVDSVTAVVSPLLGGQQREGLALMMQLARELKTLAR---DLGMAVVVTNHITR 141

Query: 175 QVDGAAMFAADPKKPIGGNIIAHASTTRLYL 205
             D   +      KP  G   +   +TR+ L
Sbjct: 142 DRDSGRL------KPALGRSWSFVPSTRILL 166


>gi|217272816 RAD51-like 3 isoform 6 [Homo sapiens]
          Length = 348

 Score = 33.9 bits (76), Expect = 0.13
 Identities = 28/86 (32%), Positives = 42/86 (48%), Gaps = 10/86 (11%)

Query: 121 LLIVDSATALYRTDYSGRG-ELSARQMHLARFLRMLLRLADEFGVAVVITNQVVAQVDGA 179
           +++VDS TA+      G+  E  A  M LAR L+ L R   + G+AVV+TN +    D  
Sbjct: 222 VVVVDSVTAVVSPLLGGQQREGLALMMQLARELKTLAR---DLGMAVVVTNHITRDRDSG 278

Query: 180 AMFAADPKKPIGGNIIAHASTTRLYL 205
            +      KP  G   +   +TR+ L
Sbjct: 279 RL------KPALGRSWSFVPSTRILL 298


>gi|217416415 RAD51-like 3 isoform 1 [Homo sapiens]
          Length = 328

 Score = 33.9 bits (76), Expect = 0.13
 Identities = 28/86 (32%), Positives = 42/86 (48%), Gaps = 10/86 (11%)

Query: 121 LLIVDSATALYRTDYSGRG-ELSARQMHLARFLRMLLRLADEFGVAVVITNQVVAQVDGA 179
           +++VDS TA+      G+  E  A  M LAR L+ L R   + G+AVV+TN +    D  
Sbjct: 202 VVVVDSVTAVVSPLLGGQQREGLALMMQLARELKTLAR---DLGMAVVVTNHITRDRDSG 258

Query: 180 AMFAADPKKPIGGNIIAHASTTRLYL 205
            +      KP  G   +   +TR+ L
Sbjct: 259 RL------KPALGRSWSFVPSTRILL 278


>gi|4885657 X-ray repair cross complementing protein 2 [Homo
           sapiens]
          Length = 280

 Score = 28.5 bits (62), Expect = 5.5
 Identities = 20/79 (25%), Positives = 38/79 (48%), Gaps = 2/79 (2%)

Query: 99  NTDHQTQLLYQASAMMVES-RYALLIVDSATALYRTDYSGRGE-LSARQMHLARFLRMLL 156
           ++ H    LY   +M        LLI+DS +A Y  D    GE ++ ++  L +  + L 
Sbjct: 122 SSTHLLLTLYSLESMFCSHPSLCLLILDSLSAFYWIDRVNGGESVNLQESTLRKCSQCLE 181

Query: 157 RLADEFGVAVVITNQVVAQ 175
           +L +++ + +  T Q + Q
Sbjct: 182 KLVNDYRLVLFATTQTIMQ 200


>gi|119392094 immunoglobulin mu binding protein 2 [Homo sapiens]
          Length = 993

 Score = 28.1 bits (61), Expect = 7.2
 Identities = 20/55 (36%), Positives = 29/55 (52%), Gaps = 1/55 (1%)

Query: 152 LRMLLRLADEFGVAVVITNQVVAQVDGAAMFAADPKKPIGGNIIAHASTTRLYLR 206
           L ++ RLA+E+G  VV T  V  ++  A M  A     + G + AH+S  R  LR
Sbjct: 420 LSLMERLAEEYGARVVRTLTVQYRMHQAIMRWASDTMYL-GQLTAHSSVARHLLR 473


>gi|153791514 tripartite motif-containing 32 [Homo sapiens]
          Length = 653

 Score = 28.1 bits (61), Expect = 7.2
 Identities = 18/73 (24%), Positives = 37/73 (50%), Gaps = 1/73 (1%)

Query: 63  IKGISEAKADKILVMAERYGLSGSDVLDNVAYARAFNTDHQTQLLYQASAMMVESRYALL 122
           ++G+S+    +   + + YG     V D +A +R F T    + + ++++ +VE +  LL
Sbjct: 170 LEGVSKDLQARYKAVLQEYGHEERRVQDELARSRKFFTGSLAE-VEKSNSQVVEEQSYLL 228

Query: 123 IVDSATALYRTDY 135
            +    A+ R DY
Sbjct: 229 NIAEVQAVSRCDY 241


>gi|153792582 tripartite motif-containing 32 [Homo sapiens]
          Length = 653

 Score = 28.1 bits (61), Expect = 7.2
 Identities = 18/73 (24%), Positives = 37/73 (50%), Gaps = 1/73 (1%)

Query: 63  IKGISEAKADKILVMAERYGLSGSDVLDNVAYARAFNTDHQTQLLYQASAMMVESRYALL 122
           ++G+S+    +   + + YG     V D +A +R F T    + + ++++ +VE +  LL
Sbjct: 170 LEGVSKDLQARYKAVLQEYGHEERRVQDELARSRKFFTGSLAE-VEKSNSQVVEEQSYLL 228

Query: 123 IVDSATALYRTDY 135
            +    A+ R DY
Sbjct: 229 NIAEVQAVSRCDY 241


>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
          Length = 1976

 Score = 27.7 bits (60), Expect = 9.4
 Identities = 34/133 (25%), Positives = 54/133 (40%), Gaps = 12/133 (9%)

Query: 37   DVKKLEEAGFHTVEAVAYAPKKELINIKGISEAKADKILV--MAERYGLSGSDVLDNVAY 94
            D KK  +    T+E++  A KK L + + +S+   +K L     E+        LD++  
Sbjct: 1375 DTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDL-- 1432

Query: 95   ARAFNTDHQTQLLYQASAMMVESRYALLIVDSATALYRTDYSGRGELSARQ-----MHLA 149
                + DHQ Q+         +    L    S +A Y  +   R E  AR+     + LA
Sbjct: 1433 --TVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARY-AEERDRAEAEAREKETKALSLA 1489

Query: 150  RFLRMLLRLADEF 162
            R L   L   +EF
Sbjct: 1490 RALEEALEAKEEF 1502


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.132    0.366 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,549,015
Number of Sequences: 37866
Number of extensions: 273897
Number of successful extensions: 589
Number of sequences better than 10.0: 15
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 576
Number of HSP's gapped (non-prelim): 18
length of query: 242
length of database: 18,247,518
effective HSP length: 99
effective length of query: 143
effective length of database: 14,498,784
effective search space: 2073326112
effective search space used: 2073326112
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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