Search of human proteins with 153945790

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal
[Homo sapiens]
         (1937 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [...  3744   0.0  
gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo...  3513   0.0  
gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo...  3513   0.0  
gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo...  3503   0.0  
gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo ...  3450   0.0  
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H...  3241   0.0  
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo...  3138   0.0  
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s...  3114   0.0  
gi|156104908 myosin heavy chain 6 [Homo sapiens]                     3104   0.0  
gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta ...  2588   0.0  
gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens]             2310   0.0  
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho...  1435   0.0  
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho...  1435   0.0  
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho...  1432   0.0  
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho...  1432   0.0  
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]   1410   0.0  
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]  1407   0.0  
gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens]         1300   0.0  
gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens]         1298   0.0  
gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens]         1291   0.0  
gi|153945715 myosin VC [Homo sapiens]                                 608   e-173
gi|215982791 myosin VA isoform 1 [Homo sapiens]                       592   e-169
gi|215982794 myosin VA isoform 2 [Homo sapiens]                       590   e-168
gi|122937345 myosin VB [Homo sapiens]                                 575   e-163
gi|28416946 myosin 18A isoform a [Homo sapiens]                       503   e-142
gi|42794779 myosin 18A isoform b [Homo sapiens]                       502   e-141
gi|154354979 myosin X [Homo sapiens]                                  495   e-139
gi|189083802 myosin VIIA isoform 2 [Homo sapiens]                     482   e-135
gi|189083800 myosin VIIA isoform 3 [Homo sapiens]                     482   e-135
gi|189083798 myosin VIIA isoform 1 [Homo sapiens]                     482   e-135

>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo
            sapiens]
          Length = 1937

 Score = 3744 bits (9710), Expect = 0.0
 Identities = 1937/1937 (100%), Positives = 1937/1937 (100%)

Query: 1    MSASSDAEMAVFGEAAPYLRKSEKERIEAQNKPFDAKTSVFVAEPKESYVKSTIQSKEGG 60
            MSASSDAEMAVFGEAAPYLRKSEKERIEAQNKPFDAKTSVFVAEPKESYVKSTIQSKEGG
Sbjct: 1    MSASSDAEMAVFGEAAPYLRKSEKERIEAQNKPFDAKTSVFVAEPKESYVKSTIQSKEGG 60

Query: 61   KVTVKTEGGATLTVREDQVFPMNPPKYDKIEDMAMMTHLHEPGVLYNLKERYAAWMIYTY 120
            KVTVKTEGGATLTVREDQVFPMNPPKYDKIEDMAMMTHLHEPGVLYNLKERYAAWMIYTY
Sbjct: 61   KVTVKTEGGATLTVREDQVFPMNPPKYDKIEDMAMMTHLHEPGVLYNLKERYAAWMIYTY 120

Query: 121  SGLFCVTVNPYKWLPVYKPEVVAAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILIT 180
            SGLFCVTVNPYKWLPVYKPEVVAAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILIT
Sbjct: 121  SGLFCVTVNPYKWLPVYKPEVVAAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILIT 180

Query: 181  GESGAGKTVNTKRVIQYFATIAVTGEKKKDESGKMQGTLEDQIISANPLLEAFGNAKTVR 240
            GESGAGKTVNTKRVIQYFATIAVTGEKKKDESGKMQGTLEDQIISANPLLEAFGNAKTVR
Sbjct: 181  GESGAGKTVNTKRVIQYFATIAVTGEKKKDESGKMQGTLEDQIISANPLLEAFGNAKTVR 240

Query: 241  NDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQITSNKKPDL 300
            NDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQITSNKKPDL
Sbjct: 241  NDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQITSNKKPDL 300

Query: 301  IEMLLITTNPYDYAFVSQGEITVPSIDDQEELMATDSAIDILGFTPEEKVSIYKLTGAVM 360
            IEMLLITTNPYDYAFVSQGEITVPSIDDQEELMATDSAIDILGFTPEEKVSIYKLTGAVM
Sbjct: 301  IEMLLITTNPYDYAFVSQGEITVPSIDDQEELMATDSAIDILGFTPEEKVSIYKLTGAVM 360

Query: 361  HYGNMKFKQKQREEQAEPDGTEVADKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTV 420
            HYGNMKFKQKQREEQAEPDGTEVADKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTV
Sbjct: 361  HYGNMKFKQKQREEQAEPDGTEVADKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTV 420

Query: 421  QQVYNAVGALAKAVYEKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLC 480
            QQVYNAVGALAKAVYEKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLC
Sbjct: 421  QQVYNAVGALAKAVYEKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLC 480

Query: 481  INFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPLGIFSILEEE 540
            INFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPLGIFSILEEE
Sbjct: 481  INFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPLGIFSILEEE 540

Query: 541  CMFPKATDTSFKNKLYDQHLGKSANFQKPKVVKGKAEAHFSLIHYAGTVDYNITGWLDKN 600
            CMFPKATDTSFKNKLYDQHLGKSANFQKPKVVKGKAEAHFSLIHYAGTVDYNITGWLDKN
Sbjct: 541  CMFPKATDTSFKNKLYDQHLGKSANFQKPKVVKGKAEAHFSLIHYAGTVDYNITGWLDKN 600

Query: 601  KDPLNDTVVGLYQKSAMKTLASLFSTYASAEADSSAKKGAKKKGSSFQTVSALFRENLNK 660
            KDPLNDTVVGLYQKSAMKTLASLFSTYASAEADSSAKKGAKKKGSSFQTVSALFRENLNK
Sbjct: 601  KDPLNDTVVGLYQKSAMKTLASLFSTYASAEADSSAKKGAKKKGSSFQTVSALFRENLNK 660

Query: 661  LMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYGD 720
            LMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYGD
Sbjct: 661  LMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYGD 720

Query: 721  FKQRYKVLNASAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMR 780
            FKQRYKVLNASAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMR
Sbjct: 721  FKQRYKVLNASAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMR 780

Query: 781  DEKLAQIITRTQAVCRGFLMRVEYQKMLQRREALFCIQYNVRAFMNVKHWPWMKLFFKIK 840
            DEKLAQIITRTQAVCRGFLMRVEYQKMLQRREALFCIQYNVRAFMNVKHWPWMKLFFKIK
Sbjct: 781  DEKLAQIITRTQAVCRGFLMRVEYQKMLQRREALFCIQYNVRAFMNVKHWPWMKLFFKIK 840

Query: 841  PLLKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADS 900
            PLLKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADS
Sbjct: 841  PLLKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADS 900

Query: 901  LADAEERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDL 960
            LADAEERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDL
Sbjct: 901  LADAEERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDL 960

Query: 961  ELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDKV 1020
            ELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDKV
Sbjct: 961  ELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDKV 1020

Query: 1021 NILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQLD 1080
            NILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQLD
Sbjct: 1021 NILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQLD 1080

Query: 1081 EKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQRS 1140
            EKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQRS
Sbjct: 1081 EKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQRS 1140

Query: 1141 DLSRELEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRKKHA 1200
            DLSRELEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRKKHA
Sbjct: 1141 DLSRELEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRKKHA 1200

Query: 1201 DSMAELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGNLEKMCRSLEDQVS 1260
            DSMAELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGNLEKMCRSLEDQVS
Sbjct: 1201 DSMAELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGNLEKMCRSLEDQVS 1260

Query: 1261 ELKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKH 1320
            ELKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKH
Sbjct: 1261 ELKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKH 1320

Query: 1321 QLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYET 1380
            QLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYET
Sbjct: 1321 QLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYET 1380

Query: 1381 DAIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNA 1440
            DAIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNA
Sbjct: 1381 DAIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNA 1440

Query: 1441 ACAALDKKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELFKVKNVYEESLDQLET 1500
            ACAALDKKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELFKVKNVYEESLDQLET
Sbjct: 1441 ACAALDKKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELFKVKNVYEESLDQLET 1500

Query: 1501 LRRENKNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGK 1560
            LRRENKNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGK
Sbjct: 1501 LRRENKNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGK 1560

Query: 1561 ILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHTRVVETMQSTLDAEIRSRNDALRVKKK 1620
            ILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHTRVVETMQSTLDAEIRSRNDALRVKKK
Sbjct: 1561 ILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHTRVVETMQSTLDAEIRSRNDALRVKKK 1620

Query: 1621 MEGDLNEMEIQLNHANRLAAESLRNYRNTQGILKETQLHLDDALRGQEDLKEQLAIVERR 1680
            MEGDLNEMEIQLNHANRLAAESLRNYRNTQGILKETQLHLDDALRGQEDLKEQLAIVERR
Sbjct: 1621 MEGDLNEMEIQLNHANRLAAESLRNYRNTQGILKETQLHLDDALRGQEDLKEQLAIVERR 1680

Query: 1681 ANLLQAEIEELWATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQL 1740
            ANLLQAEIEELWATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQL
Sbjct: 1681 ANLLQAEIEELWATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQL 1740

Query: 1741 QSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRL 1800
            QSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRL
Sbjct: 1741 QSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRL 1800

Query: 1801 DEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHERRVKELTYQTEED 1860
            DEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHERRVKELTYQTEED
Sbjct: 1801 DEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHERRVKELTYQTEED 1860

Query: 1861 RKNVLRLQDLVDKLQAKVKSYKRQAEEAEEQSNANLSKFRKLQHELEEAEERADIAESQV 1920
            RKNVLRLQDLVDKLQAKVKSYKRQAEEAEEQSNANLSKFRKLQHELEEAEERADIAESQV
Sbjct: 1861 RKNVLRLQDLVDKLQAKVKSYKRQAEEAEEQSNANLSKFRKLQHELEEAEERADIAESQV 1920

Query: 1921 NKLRVKSREVHTKISAE 1937
            NKLRVKSREVHTKISAE
Sbjct: 1921 NKLRVKSREVHTKISAE 1937


>gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo
            sapiens]
          Length = 1941

 Score = 3513 bits (9110), Expect = 0.0
 Identities = 1796/1939 (92%), Positives = 1879/1939 (96%), Gaps = 5/1939 (0%)

Query: 4    SSDAEMAVFGEAAPYLRKSEKERIEAQNKPFDAKTSVFVAEPKESYVKSTIQSKEGGKVT 63
            SSD+E+AVFGEAAP+LRKSE+ERIEAQN+PFDAKTSVFVAEPKES+VK TIQS+EGGKVT
Sbjct: 2    SSDSELAVFGEAAPFLRKSERERIEAQNRPFDAKTSVFVAEPKESFVKGTIQSREGGKVT 61

Query: 64   VKTEGGATLTVREDQVFPMNPPKYDKIEDMAMMTHLHEPGVLYNLKERYAAWMIYTYSGL 123
            VKTEGGATLTV++DQVFPMNPPKYDKIEDMAMMTHLHEP VLYNLKERYAAWMIYTYSGL
Sbjct: 62   VKTEGGATLTVKDDQVFPMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGL 121

Query: 124  FCVTVNPYKWLPVYKPEVVAAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGES 183
            FCVTVNPYKWLPVYKPEVV AYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGES
Sbjct: 122  FCVTVNPYKWLPVYKPEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGES 181

Query: 184  GAGKTVNTKRVIQYFATIAVTGEKKKDE--SGKMQGTLEDQIISANPLLEAFGNAKTVRN 241
            GAGKTVNTKRVIQYFATIAVTGEKKK+E  SGK+QGTLEDQIISANPLLEAFGNAKTVRN
Sbjct: 182  GAGKTVNTKRVIQYFATIAVTGEKKKEEITSGKIQGTLEDQIISANPLLEAFGNAKTVRN 241

Query: 242  DNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQITSNKKPDLI 301
            DNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRV FQLKAERSYHIFYQITSNKKP+LI
Sbjct: 242  DNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVVFQLKAERSYHIFYQITSNKKPELI 301

Query: 302  EMLLITTNPYDYAFVSQGEITVPSIDDQEELMATDSAIDILGFTPEEKVSIYKLTGAVMH 361
            EMLLITTNPYDY FVSQGEI+V SIDDQEELMATDSAIDILGFT EEKVSIYKLTGAVMH
Sbjct: 302  EMLLITTNPYDYPFVSQGEISVASIDDQEELMATDSAIDILGFTNEEKVSIYKLTGAVMH 361

Query: 362  YGNMKFKQKQREEQAEPDGTEVADKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTVQ 421
            YGN+KFKQKQREEQAEPDGTEVADKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTV+
Sbjct: 362  YGNLKFKQKQREEQAEPDGTEVADKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTVE 421

Query: 422  QVYNAVGALAKAVYEKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCI 481
            QV NAVGALAKAVYEKMFLWMV RINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCI
Sbjct: 422  QVSNAVGALAKAVYEKMFLWMVARINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCI 481

Query: 482  NFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPLGIFSILEEEC 541
            NFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKP+GIFSILEEEC
Sbjct: 482  NFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEEC 541

Query: 542  MFPKATDTSFKNKLYDQHLGKSANFQKPKVVKGKAEAHFSLIHYAGTVDYNITGWLDKNK 601
            MFPKATDTSFKNKLYDQHLGKSANFQKPKVVKGKAEAHF+LIHYAG VDYNITGWL+KNK
Sbjct: 542  MFPKATDTSFKNKLYDQHLGKSANFQKPKVVKGKAEAHFALIHYAGVVDYNITGWLEKNK 601

Query: 602  DPLNDTVVGLYQKSAMKTLASLFSTYASAEADSS---AKKGAKKKGSSFQTVSALFRENL 658
            DPLN+TVVGLYQKSAMKTLA LFS   +AE + +   AKKG KKKGSSFQTVSALFRENL
Sbjct: 602  DPLNETVVGLYQKSAMKTLAQLFSGAQTAEGEGAGGGAKKGGKKKGSSFQTVSALFRENL 661

Query: 659  NKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILY 718
            NKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILY
Sbjct: 662  NKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILY 721

Query: 719  GDFKQRYKVLNASAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEE 778
             DFKQRYKVLNASAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEE
Sbjct: 722  ADFKQRYKVLNASAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEE 781

Query: 779  MRDEKLAQIITRTQAVCRGFLMRVEYQKMLQRREALFCIQYNVRAFMNVKHWPWMKLFFK 838
            MRD+KLAQ+ITRTQA CRGFL RVEYQ+M++RREA+FCIQYN+R+FMNVKHWPWMKLFFK
Sbjct: 782  MRDDKLAQLITRTQARCRGFLARVEYQRMVERREAIFCIQYNIRSFMNVKHWPWMKLFFK 841

Query: 839  IKPLLKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEA 898
            IKPLLKSAETEKEMATMKEEFQK KDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQ+EA
Sbjct: 842  IKPLLKSAETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEA 901

Query: 899  DSLADAEERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDID 958
            + LADAEERC+QLIK KIQLEAKIKEVTERAE+EEEINAELTAKKRKLEDECSELKKDID
Sbjct: 902  EGLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDID 961

Query: 959  DLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEED 1018
            DLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKL+KEKKALQE HQQTLDDLQAEED
Sbjct: 962  DLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEED 1021

Query: 1019 KVNILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQ 1078
            KVN LTKAK KLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQES MD+EN+KQQ
Sbjct: 1022 KVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQ 1081

Query: 1079 LDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQ 1138
            LDEKL+KKEFEISNL SKIEDEQA+ IQLQKKIKELQARIEEL EEIEAERASRAKAEKQ
Sbjct: 1082 LDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQ 1141

Query: 1139 RSDLSRELEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRKK 1198
            RSDLSRELEEISERLEEAGGATSAQ+E+NKKREAEFQK+RRDLEEATLQHEA  A LRKK
Sbjct: 1142 RSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKK 1201

Query: 1199 HADSMAELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGNLEKMCRSLEDQ 1258
            HADS+AELGEQIDNLQRVKQKLEKEKSE+KME DDL+SN E +SKAKGNLEKMCR+LEDQ
Sbjct: 1202 HADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQ 1261

Query: 1259 VSELKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEEL 1318
            +SELK+KEEEQQRLINDLTAQR RLQTE+GE+SRQLDEK+ALVSQLSR KQA TQQIEEL
Sbjct: 1262 LSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEEL 1321

Query: 1319 KHQLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKY 1378
            K QLEEE KAKNALAHALQSSRHDCDLLREQYEEEQE KAELQRALSKAN+EVAQWRTKY
Sbjct: 1322 KRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKY 1381

Query: 1379 ETDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERS 1438
            ETDAIQRTEELEEAKKKLAQRLQ AEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVER+
Sbjct: 1382 ETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERT 1441

Query: 1439 NAACAALDKKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELFKVKNVYEESLDQL 1498
            NAACAALDKKQRNFDK+L+EWKQK EET AELEASQKE+RSL TELFK+KN YEESLDQL
Sbjct: 1442 NAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQL 1501

Query: 1499 ETLRRENKNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEE 1558
            ETL+RENKNLQQEISDLTEQIAEGGK+IHELEKIKKQVEQEKCE+QAALEEAEASLEHEE
Sbjct: 1502 ETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEE 1561

Query: 1559 GKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHTRVVETMQSTLDAEIRSRNDALRVK 1618
            GKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNH R+VE+MQSTLDAEIRSRNDA+R+K
Sbjct: 1562 GKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLK 1621

Query: 1619 KKMEGDLNEMEIQLNHANRLAAESLRNYRNTQGILKETQLHLDDALRGQEDLKEQLAIVE 1678
            KKMEGDLNEMEIQLNHANR+AAE+LRNYRNTQGILK+TQ+HLDDALR QEDLKEQLA+VE
Sbjct: 1622 KKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVE 1681

Query: 1679 RRANLLQAEIEELWATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVS 1738
            RRANLLQAEIEEL ATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLE D+S
Sbjct: 1682 RRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDIS 1741

Query: 1739 QLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQH 1798
            Q+Q E+E+++QE+RNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKN+EQTVKDLQ 
Sbjct: 1742 QMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQL 1801

Query: 1799 RLDEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHERRVKELTYQTE 1858
            RLDEAEQLALKGGKKQIQKLEARVRELEGEVE+EQKRNAEAVKGLRKHERRVKELTYQTE
Sbjct: 1802 RLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTE 1861

Query: 1859 EDRKNVLRLQDLVDKLQAKVKSYKRQAEEAEEQSNANLSKFRKLQHELEEAEERADIAES 1918
            EDRKN+LRLQDLVDKLQAKVKSYKRQAEEAEEQSN NL+KFRKLQHELEEAEERADIAES
Sbjct: 1862 EDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAES 1921

Query: 1919 QVNKLRVKSREVHTKISAE 1937
            QVNKLRVKSREVHTK+ +E
Sbjct: 1922 QVNKLRVKSREVHTKVISE 1940


>gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo
            sapiens]
          Length = 1941

 Score = 3513 bits (9110), Expect = 0.0
 Identities = 1796/1939 (92%), Positives = 1879/1939 (96%), Gaps = 5/1939 (0%)

Query: 4    SSDAEMAVFGEAAPYLRKSEKERIEAQNKPFDAKTSVFVAEPKESYVKSTIQSKEGGKVT 63
            SSD+E+AVFGEAAP+LRKSE+ERIEAQN+PFDAKTSVFVAEPKES+VK TIQS+EGGKVT
Sbjct: 2    SSDSELAVFGEAAPFLRKSERERIEAQNRPFDAKTSVFVAEPKESFVKGTIQSREGGKVT 61

Query: 64   VKTEGGATLTVREDQVFPMNPPKYDKIEDMAMMTHLHEPGVLYNLKERYAAWMIYTYSGL 123
            VKTEGGATLTV++DQVFPMNPPKYDKIEDMAMMTHLHEP VLYNLKERYAAWMIYTYSGL
Sbjct: 62   VKTEGGATLTVKDDQVFPMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGL 121

Query: 124  FCVTVNPYKWLPVYKPEVVAAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGES 183
            FCVTVNPYKWLPVYKPEVV AYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGES
Sbjct: 122  FCVTVNPYKWLPVYKPEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGES 181

Query: 184  GAGKTVNTKRVIQYFATIAVTGEKKKDE--SGKMQGTLEDQIISANPLLEAFGNAKTVRN 241
            GAGKTVNTKRVIQYFATIAVTGEKKK+E  SGK+QGTLEDQIISANPLLEAFGNAKTVRN
Sbjct: 182  GAGKTVNTKRVIQYFATIAVTGEKKKEEITSGKIQGTLEDQIISANPLLEAFGNAKTVRN 241

Query: 242  DNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQITSNKKPDLI 301
            DNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRV FQLKAERSYHIFYQITSNKKP+LI
Sbjct: 242  DNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVVFQLKAERSYHIFYQITSNKKPELI 301

Query: 302  EMLLITTNPYDYAFVSQGEITVPSIDDQEELMATDSAIDILGFTPEEKVSIYKLTGAVMH 361
            EMLLITTNPYDY FVSQGEI+V SIDDQEELMATDSAIDILGFT EEKVSIYKLTGAVMH
Sbjct: 302  EMLLITTNPYDYPFVSQGEISVASIDDQEELMATDSAIDILGFTNEEKVSIYKLTGAVMH 361

Query: 362  YGNMKFKQKQREEQAEPDGTEVADKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTVQ 421
            YGN+KFKQKQREEQAEPDGTEVADKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTV+
Sbjct: 362  YGNLKFKQKQREEQAEPDGTEVADKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTVE 421

Query: 422  QVYNAVGALAKAVYEKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCI 481
            QV NAVGALAKAVYEKMFLWMV RINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCI
Sbjct: 422  QVSNAVGALAKAVYEKMFLWMVARINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCI 481

Query: 482  NFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPLGIFSILEEEC 541
            NFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKP+GIFSILEEEC
Sbjct: 482  NFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEEC 541

Query: 542  MFPKATDTSFKNKLYDQHLGKSANFQKPKVVKGKAEAHFSLIHYAGTVDYNITGWLDKNK 601
            MFPKATDTSFKNKLYDQHLGKSANFQKPKVVKGKAEAHF+LIHYAG VDYNITGWL+KNK
Sbjct: 542  MFPKATDTSFKNKLYDQHLGKSANFQKPKVVKGKAEAHFALIHYAGVVDYNITGWLEKNK 601

Query: 602  DPLNDTVVGLYQKSAMKTLASLFSTYASAEADSS---AKKGAKKKGSSFQTVSALFRENL 658
            DPLN+TVVGLYQKSAMKTLA LFS   +AE + +   AKKG KKKGSSFQTVSALFRENL
Sbjct: 602  DPLNETVVGLYQKSAMKTLAQLFSGAQTAEGEGAGGGAKKGGKKKGSSFQTVSALFRENL 661

Query: 659  NKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILY 718
            NKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILY
Sbjct: 662  NKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILY 721

Query: 719  GDFKQRYKVLNASAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEE 778
             DFKQRYKVLNASAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEE
Sbjct: 722  ADFKQRYKVLNASAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEE 781

Query: 779  MRDEKLAQIITRTQAVCRGFLMRVEYQKMLQRREALFCIQYNVRAFMNVKHWPWMKLFFK 838
            MRD+KLAQ+ITRTQA CRGFL RVEYQ+M++RREA+FCIQYN+R+FMNVKHWPWMKLFFK
Sbjct: 782  MRDDKLAQLITRTQARCRGFLARVEYQRMVERREAIFCIQYNIRSFMNVKHWPWMKLFFK 841

Query: 839  IKPLLKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEA 898
            IKPLLKSAETEKEMATMKEEFQK KDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQ+EA
Sbjct: 842  IKPLLKSAETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEA 901

Query: 899  DSLADAEERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDID 958
            + LADAEERC+QLIK KIQLEAKIKEVTERAE+EEEINAELTAKKRKLEDECSELKKDID
Sbjct: 902  EGLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDID 961

Query: 959  DLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEED 1018
            DLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKL+KEKKALQE HQQTLDDLQAEED
Sbjct: 962  DLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEED 1021

Query: 1019 KVNILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQ 1078
            KVN LTKAK KLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQES MD+EN+KQQ
Sbjct: 1022 KVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQ 1081

Query: 1079 LDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQ 1138
            LDEKL+KKEFEISNL SKIEDEQA+ IQLQKKIKELQARIEEL EEIEAERASRAKAEKQ
Sbjct: 1082 LDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQ 1141

Query: 1139 RSDLSRELEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRKK 1198
            RSDLSRELEEISERLEEAGGATSAQ+E+NKKREAEFQK+RRDLEEATLQHEA  A LRKK
Sbjct: 1142 RSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKK 1201

Query: 1199 HADSMAELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGNLEKMCRSLEDQ 1258
            HADS+AELGEQIDNLQRVKQKLEKEKSE+KME DDL+SN E +SKAKGNLEKMCR+LEDQ
Sbjct: 1202 HADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQ 1261

Query: 1259 VSELKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEEL 1318
            +SELK+KEEEQQRLINDLTAQR RLQTE+GE+SRQLDEK+ALVSQLSR KQA TQQIEEL
Sbjct: 1262 LSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEEL 1321

Query: 1319 KHQLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKY 1378
            K QLEEE KAKNALAHALQSSRHDCDLLREQYEEEQE KAELQRALSKAN+EVAQWRTKY
Sbjct: 1322 KRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKY 1381

Query: 1379 ETDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERS 1438
            ETDAIQRTEELEEAKKKLAQRLQ AEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVER+
Sbjct: 1382 ETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERT 1441

Query: 1439 NAACAALDKKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELFKVKNVYEESLDQL 1498
            NAACAALDKKQRNFDK+L+EWKQK EET AELEASQKE+RSL TELFK+KN YEESLDQL
Sbjct: 1442 NAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQL 1501

Query: 1499 ETLRRENKNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEE 1558
            ETL+RENKNLQQEISDLTEQIAEGGK+IHELEKIKKQVEQEKCE+QAALEEAEASLEHEE
Sbjct: 1502 ETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEE 1561

Query: 1559 GKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHTRVVETMQSTLDAEIRSRNDALRVK 1618
            GKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNH R+VE+MQSTLDAEIRSRNDA+R+K
Sbjct: 1562 GKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLK 1621

Query: 1619 KKMEGDLNEMEIQLNHANRLAAESLRNYRNTQGILKETQLHLDDALRGQEDLKEQLAIVE 1678
            KKMEGDLNEMEIQLNHANR+AAE+LRNYRNTQGILK+TQ+HLDDALR QEDLKEQLA+VE
Sbjct: 1622 KKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVE 1681

Query: 1679 RRANLLQAEIEELWATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVS 1738
            RRANLLQAEIEEL ATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLE D+S
Sbjct: 1682 RRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDIS 1741

Query: 1739 QLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQH 1798
            Q+Q E+E+++QE+RNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKN+EQTVKDLQ 
Sbjct: 1742 QMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQL 1801

Query: 1799 RLDEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHERRVKELTYQTE 1858
            RLDEAEQLALKGGKKQIQKLEARVRELEGEVE+EQKRNAEAVKGLRKHERRVKELTYQTE
Sbjct: 1802 RLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTE 1861

Query: 1859 EDRKNVLRLQDLVDKLQAKVKSYKRQAEEAEEQSNANLSKFRKLQHELEEAEERADIAES 1918
            EDRKN+LRLQDLVDKLQAKVKSYKRQAEEAEEQSN NL+KFRKLQHELEEAEERADIAES
Sbjct: 1862 EDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAES 1921

Query: 1919 QVNKLRVKSREVHTKISAE 1937
            QVNKLRVKSREVHTK+ +E
Sbjct: 1922 QVNKLRVKSREVHTKVISE 1940


>gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo
            sapiens]
          Length = 1939

 Score = 3503 bits (9084), Expect = 0.0
 Identities = 1786/1937 (92%), Positives = 1874/1937 (96%), Gaps = 3/1937 (0%)

Query: 4    SSDAEMAVFGEAAPYLRKSEKERIEAQNKPFDAKTSVFVAEPKESYVKSTIQSKEGGKVT 63
            SSD+EMA+FGEAAP+LRKSE+ERIEAQNKPFDAKTSVFV +PKES+VK+T+QS+EGGKVT
Sbjct: 2    SSDSEMAIFGEAAPFLRKSERERIEAQNKPFDAKTSVFVVDPKESFVKATVQSREGGKVT 61

Query: 64   VKTEGGATLTVREDQVFPMNPPKYDKIEDMAMMTHLHEPGVLYNLKERYAAWMIYTYSGL 123
             KTE GAT+TV++DQVFPMNPPKYDKIEDMAMMTHLHEP VLYNLKERYAAWMIYTYSGL
Sbjct: 62   AKTEAGATVTVKDDQVFPMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGL 121

Query: 124  FCVTVNPYKWLPVYKPEVVAAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGES 183
            FCVTVNPYKWLPVY  EVV AYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGES
Sbjct: 122  FCVTVNPYKWLPVYNAEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGES 181

Query: 184  GAGKTVNTKRVIQYFATIAVTGEKKKDE--SGKMQGTLEDQIISANPLLEAFGNAKTVRN 241
            GAGKTVNTKRVIQYFATIAVTGEKKK+E  SGKMQGTLEDQIISANPLLEAFGNAKTVRN
Sbjct: 182  GAGKTVNTKRVIQYFATIAVTGEKKKEEVTSGKMQGTLEDQIISANPLLEAFGNAKTVRN 241

Query: 242  DNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQITSNKKPDLI 301
            DNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQI SNKKPDLI
Sbjct: 242  DNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQIMSNKKPDLI 301

Query: 302  EMLLITTNPYDYAFVSQGEITVPSIDDQEELMATDSAIDILGFTPEEKVSIYKLTGAVMH 361
            EMLLITTNPYDYAFVSQGEITVPSIDDQEELMATDSAI+ILGFT +E+VSIYKLTGAVMH
Sbjct: 302  EMLLITTNPYDYAFVSQGEITVPSIDDQEELMATDSAIEILGFTSDERVSIYKLTGAVMH 361

Query: 362  YGNMKFKQKQREEQAEPDGTEVADKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTVQ 421
            YGNMKFKQKQREEQAEPDGTEVADKAAYLQ+LNSADLLKALCYPRVKVGNEYVTKGQTVQ
Sbjct: 362  YGNMKFKQKQREEQAEPDGTEVADKAAYLQNLNSADLLKALCYPRVKVGNEYVTKGQTVQ 421

Query: 422  QVYNAVGALAKAVYEKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCI 481
            QVYNAVGALAKAVY+KMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCI
Sbjct: 422  QVYNAVGALAKAVYDKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCI 481

Query: 482  NFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPLGIFSILEEEC 541
            NFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKP+GIFSILEEEC
Sbjct: 482  NFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEEC 541

Query: 542  MFPKATDTSFKNKLYDQHLGKSANFQKPKVVKGKAEAHFSLIHYAGTVDYNITGWLDKNK 601
            MFPKATDTSFKNKLY+QHLGKS NFQKPK  KGK EAHFSLIHYAGTVDYNI GWLDKNK
Sbjct: 542  MFPKATDTSFKNKLYEQHLGKSNNFQKPKPAKGKPEAHFSLIHYAGTVDYNIAGWLDKNK 601

Query: 602  DPLNDTVVGLYQKSAMKTLASLFSTYASAEADSSA-KKGAKKKGSSFQTVSALFRENLNK 660
            DPLN+TVVGLYQKSAMKTLA LF     AEA++   KKG KKKGSSFQTVSALFRENLNK
Sbjct: 602  DPLNETVVGLYQKSAMKTLALLFVGATGAEAEAGGGKKGGKKKGSSFQTVSALFRENLNK 661

Query: 661  LMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYGD 720
            LMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILY D
Sbjct: 662  LMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYAD 721

Query: 721  FKQRYKVLNASAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMR 780
            FKQRYKVLNASAIPEGQFIDSKKASEKLL SIDIDHTQYKFGHTKVFFKAGLLGLLEEMR
Sbjct: 722  FKQRYKVLNASAIPEGQFIDSKKASEKLLGSIDIDHTQYKFGHTKVFFKAGLLGLLEEMR 781

Query: 781  DEKLAQIITRTQAVCRGFLMRVEYQKMLQRREALFCIQYNVRAFMNVKHWPWMKLFFKIK 840
            DEKLAQ+ITRTQA+CRGFL RVEYQKM++RRE++FCIQYNVRAFMNVKHWPWMKL+FKIK
Sbjct: 782  DEKLAQLITRTQAMCRGFLARVEYQKMVERRESIFCIQYNVRAFMNVKHWPWMKLYFKIK 841

Query: 841  PLLKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADS 900
            PLLKSAETEKEMA MKEEF+KTK+ELAK+EAKRKELEEKMVTL++EKNDLQLQVQ+EADS
Sbjct: 842  PLLKSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADS 901

Query: 901  LADAEERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDL 960
            LADAEERC+QLIK KIQLEAKIKEVTERAE+EEEINAELTAKKRKLEDECSELKKDIDDL
Sbjct: 902  LADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDL 961

Query: 961  ELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDKV 1020
            ELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKL+KEKKALQE HQQTLDDLQAEEDKV
Sbjct: 962  ELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKV 1021

Query: 1021 NILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQLD 1080
            N LTKAK KLEQQVDDLEGSLEQEKK+RMDLERAKRKLEGDLKLAQESTMD+ENDKQQLD
Sbjct: 1022 NTLTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDLKLAQESTMDIENDKQQLD 1081

Query: 1081 EKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQRS 1140
            EKL+KKEFE+S L SKIEDEQA+ +QLQKKIKELQARIEEL EEIEAERASRAKAEKQRS
Sbjct: 1082 EKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRS 1141

Query: 1141 DLSRELEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRKKHA 1200
            DLSRELEEISERLEEAGGATSAQ+E+NKKREAEFQK+RRDLEEATLQHEA  A LRKKHA
Sbjct: 1142 DLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHA 1201

Query: 1201 DSMAELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGNLEKMCRSLEDQVS 1260
            DS+AELGEQIDNLQRVKQKLEKEKSE+KME DDL+SN E +SKAKGNLEKMCR+LEDQ+S
Sbjct: 1202 DSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQLS 1261

Query: 1261 ELKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKH 1320
            E+KTKEEEQQRLINDLTAQRARLQTE+GEYSRQLDEKD LVSQLSR KQA TQQIEELK 
Sbjct: 1262 EIKTKEEEQQRLINDLTAQRARLQTESGEYSRQLDEKDTLVSQLSRGKQAFTQQIEELKR 1321

Query: 1321 QLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYET 1380
            QLEEE KAK+ALAHALQSSRHDCDLLREQYEEEQE KAELQRA+SKANSEVAQWRTKYET
Sbjct: 1322 QLEEEIKAKSALAHALQSSRHDCDLLREQYEEEQEAKAELQRAMSKANSEVAQWRTKYET 1381

Query: 1381 DAIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNA 1440
            DAIQRTEELEEAKKKLAQRLQ+AEEHVEAVNAKCASLEKTKQRLQNEVEDLM+DVER+NA
Sbjct: 1382 DAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNA 1441

Query: 1441 ACAALDKKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELFKVKNVYEESLDQLET 1500
            ACAALDKKQRNFDK+L+EWKQK EET AELEASQKESRSLSTELFK+KN YEESLDQLET
Sbjct: 1442 ACAALDKKQRNFDKILAEWKQKCEETHAELEASQKESRSLSTELFKIKNAYEESLDQLET 1501

Query: 1501 LRRENKNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGK 1560
            L+RENKNLQQEISDLTEQIAEGGK+IHELEKIKKQVEQEK E+QAALEEAEASLEHEEGK
Sbjct: 1502 LKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKSELQAALEEAEASLEHEEGK 1561

Query: 1561 ILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHTRVVETMQSTLDAEIRSRNDALRVKKK 1620
            ILRIQLELNQVKSEVDRKIAEKDEEIDQ+KRNH R+VE+MQSTLDAEIRSRNDA+R+KKK
Sbjct: 1562 ILRIQLELNQVKSEVDRKIAEKDEEIDQMKRNHIRIVESMQSTLDAEIRSRNDAIRLKKK 1621

Query: 1621 MEGDLNEMEIQLNHANRLAAESLRNYRNTQGILKETQLHLDDALRGQEDLKEQLAIVERR 1680
            MEGDLNEMEIQLNHANR+AAE+LRNYRNTQ ILK+TQLHLDDALR QEDLKEQLA+VERR
Sbjct: 1622 MEGDLNEMEIQLNHANRMAAEALRNYRNTQAILKDTQLHLDDALRSQEDLKEQLAMVERR 1681

Query: 1681 ANLLQAEIEELWATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQL 1740
            ANLLQAEIEEL ATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLE D+SQ+
Sbjct: 1682 ANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQI 1741

Query: 1741 QSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRL 1800
            Q E+E++IQE+RNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRL
Sbjct: 1742 QGEMEDIIQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRL 1801

Query: 1801 DEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHERRVKELTYQTEED 1860
            DEAEQLALKGGKKQIQKLEARVRELEGEVE+EQKRN EAVKGLRKHER+VKELTYQTEED
Sbjct: 1802 DEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNVEAVKGLRKHERKVKELTYQTEED 1861

Query: 1861 RKNVLRLQDLVDKLQAKVKSYKRQAEEAEEQSNANLSKFRKLQHELEEAEERADIAESQV 1920
            RKN+LRLQDLVDKLQAKVKSYKRQAEEAEEQSN NLSKFR++QHELEEAEERADIAESQV
Sbjct: 1862 RKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNVNLSKFRRIQHELEEAEERADIAESQV 1921

Query: 1921 NKLRVKSREVHTKISAE 1937
            NKLRVKSREVHTKI +E
Sbjct: 1922 NKLRVKSREVHTKIISE 1938


>gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo
            sapiens]
          Length = 1939

 Score = 3450 bits (8945), Expect = 0.0
 Identities = 1750/1937 (90%), Positives = 1859/1937 (95%), Gaps = 3/1937 (0%)

Query: 4    SSDAEMAVFGEAAPYLRKSEKERIEAQNKPFDAKTSVFVAEPKESYVKSTIQSKEGGKVT 63
            SSD+EMA+FGEAAP+LRKSEKERIEAQNKPFDAKTSVFV +PKESYVK+ +QS+EGGKVT
Sbjct: 2    SSDSEMAIFGEAAPFLRKSEKERIEAQNKPFDAKTSVFVVDPKESYVKAIVQSREGGKVT 61

Query: 64   VKTEGGATLTVREDQVFPMNPPKYDKIEDMAMMTHLHEPGVLYNLKERYAAWMIYTYSGL 123
             KTE GAT+TV+EDQVF MNPPKYDKIEDMAMMTHLHEP VLYNLKERYAAWMIYTYSGL
Sbjct: 62   AKTEAGATVTVKEDQVFSMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGL 121

Query: 124  FCVTVNPYKWLPVYKPEVVAAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGES 183
            FCVTVNPYKWLPVY PEVV AYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGES
Sbjct: 122  FCVTVNPYKWLPVYNPEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGES 181

Query: 184  GAGKTVNTKRVIQYFATIAVTGEKKKDE--SGKMQGTLEDQIISANPLLEAFGNAKTVRN 241
            GAGKTVNTKRVIQYFATIAVTGEKKK+E  SGKMQGTLEDQIISANPLLEAFGNAKTVRN
Sbjct: 182  GAGKTVNTKRVIQYFATIAVTGEKKKEEPASGKMQGTLEDQIISANPLLEAFGNAKTVRN 241

Query: 242  DNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQITSNKKPDLI 301
            DNSSRFGKFIRIHFG TGKLASADIETYLLEKSRVTFQLKAERSYHIFYQI SNKKP+LI
Sbjct: 242  DNSSRFGKFIRIHFGATGKLASADIETYLLEKSRVTFQLKAERSYHIFYQILSNKKPELI 301

Query: 302  EMLLITTNPYDYAFVSQGEITVPSIDDQEELMATDSAIDILGFTPEEKVSIYKLTGAVMH 361
            EMLLITTNPYD+AFVSQGEITVPSIDDQEELMATDSA+DILGFT +EKV+IYKLTGAVMH
Sbjct: 302  EMLLITTNPYDFAFVSQGEITVPSIDDQEELMATDSAVDILGFTADEKVAIYKLTGAVMH 361

Query: 362  YGNMKFKQKQREEQAEPDGTEVADKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTVQ 421
            YGNMKFKQKQREEQAEPDGTEVADKAAYL SLNSADLLK+LCYPRVKVGNE+VTKGQTVQ
Sbjct: 362  YGNMKFKQKQREEQAEPDGTEVADKAAYLTSLNSADLLKSLCYPRVKVGNEFVTKGQTVQ 421

Query: 422  QVYNAVGALAKAVYEKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCI 481
            QVYNAVGALAKA+YEKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCI
Sbjct: 422  QVYNAVGALAKAIYEKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCI 481

Query: 482  NFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPLGIFSILEEEC 541
            NFTNEKLQQFFNHHMFVLEQEEYKKEGIEW FIDFGMDLAACIELIEKP+GIFSILEEEC
Sbjct: 482  NFTNEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLAACIELIEKPMGIFSILEEEC 541

Query: 542  MFPKATDTSFKNKLYDQHLGKSANFQKPKVVKGKAEAHFSLIHYAGTVDYNITGWLDKNK 601
            MFPKATDTSFKNKLY+QHLGKS NFQKPK  KGK EAHFSL+HYAGTVDYNI GWLDKNK
Sbjct: 542  MFPKATDTSFKNKLYEQHLGKSNNFQKPKPAKGKPEAHFSLVHYAGTVDYNIAGWLDKNK 601

Query: 602  DPLNDTVVGLYQKSAMKTLASLFSTYASAEADSSA-KKGAKKKGSSFQTVSALFRENLNK 660
            DPLN+TVVGLYQKSAMKTLA LFS   +AEA+    KKG KKKGSSFQTVSALFRENLNK
Sbjct: 602  DPLNETVVGLYQKSAMKTLAFLFSGAQTAEAEGGGGKKGGKKKGSSFQTVSALFRENLNK 661

Query: 661  LMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYGD 720
            LMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILY D
Sbjct: 662  LMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYAD 721

Query: 721  FKQRYKVLNASAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMR 780
            FKQRYKVLNASAIPEGQFIDSKKASEKLL SI+IDHTQYKFGHTKVFFKAGLLG LEEMR
Sbjct: 722  FKQRYKVLNASAIPEGQFIDSKKASEKLLGSIEIDHTQYKFGHTKVFFKAGLLGTLEEMR 781

Query: 781  DEKLAQIITRTQAVCRGFLMRVEYQKMLQRREALFCIQYNVRAFMNVKHWPWMKLFFKIK 840
            DEKLAQ+ITRTQA+CRGFLMRVE++KM++RRE++FCIQYN+RAFMNVKHWPWMKL+FKIK
Sbjct: 782  DEKLAQLITRTQAICRGFLMRVEFRKMMERRESIFCIQYNIRAFMNVKHWPWMKLYFKIK 841

Query: 841  PLLKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADS 900
            PLLKSAETEKEMA MKEEF+KTK+ELAK+EAKRKELEEKMVTL++EKNDLQLQVQ+EAD+
Sbjct: 842  PLLKSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADA 901

Query: 901  LADAEERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDL 960
            LADAEERC+QLIK KIQLEAKIKEVTERAE+EEEINAELTAKKRKLEDECSELKKDIDDL
Sbjct: 902  LADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDL 961

Query: 961  ELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDKV 1020
            ELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKL+KEKKALQE HQQTLDDLQ EEDKV
Sbjct: 962  ELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQMEEDKV 1021

Query: 1021 NILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQLD 1080
            N LTKAKTKLEQQVDDLEGSLEQEKKL MDLERAKRKLEGDLKLAQESTMD ENDKQQL+
Sbjct: 1022 NTLTKAKTKLEQQVDDLEGSLEQEKKLCMDLERAKRKLEGDLKLAQESTMDTENDKQQLN 1081

Query: 1081 EKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQRS 1140
            EKL+KKEFE+SNL  KIEDEQA+ IQLQKKIKELQARIEEL EEIEAERASRAKAEKQRS
Sbjct: 1082 EKLKKKEFEMSNLQGKIEDEQALAIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRS 1141

Query: 1141 DLSRELEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRKKHA 1200
            DLSRELEEISERLEEAGGATSAQ+E+NKKREAEFQK+RRDLEE+TLQHEA  AALRKKHA
Sbjct: 1142 DLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEESTLQHEATAAALRKKHA 1201

Query: 1201 DSMAELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGNLEKMCRSLEDQVS 1260
            DS+AELGEQID+LQRVKQKLEKEKSELKME +DL+SN E +SKAK N EKMCR+LEDQ+S
Sbjct: 1202 DSVAELGEQIDSLQRVKQKLEKEKSELKMEINDLASNMETVSKAKANFEKMCRTLEDQLS 1261

Query: 1261 ELKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKH 1320
            E+KTKEEEQQRLIN+L+AQ+ARL TE+GE+SRQLDEKDA+VSQLSR KQA TQQIEELK 
Sbjct: 1262 EIKTKEEEQQRLINELSAQKARLHTESGEFSRQLDEKDAMVSQLSRGKQAFTQQIEELKR 1321

Query: 1321 QLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYET 1380
            QLEEETKAK+ LAHALQS+RHDCDLLREQYEEEQE KAELQR +SKANSEVAQWRTKYET
Sbjct: 1322 QLEEETKAKSTLAHALQSARHDCDLLREQYEEEQEAKAELQRGMSKANSEVAQWRTKYET 1381

Query: 1381 DAIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNA 1440
            DAIQRTEELEEAKKKLAQRLQ+AEEHVEAVN+KCASLEKTKQRLQNEVEDLM+DVERSNA
Sbjct: 1382 DAIQRTEELEEAKKKLAQRLQDAEEHVEAVNSKCASLEKTKQRLQNEVEDLMIDVERSNA 1441

Query: 1441 ACAALDKKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELFKVKNVYEESLDQLET 1500
            AC ALDKKQRNFDKVL+EWKQKYEETQAELEASQKESRSLSTELFKVKN YEESLD LET
Sbjct: 1442 ACIALDKKQRNFDKVLAEWKQKYEETQAELEASQKESRSLSTELFKVKNAYEESLDHLET 1501

Query: 1501 LRRENKNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGK 1560
            L+RENKNLQQEISDLTEQIAEGGK IHELEK+KKQ++ EK E+Q +LEEAEASLEHEEGK
Sbjct: 1502 LKRENKNLQQEISDLTEQIAEGGKHIHELEKVKKQLDHEKSELQTSLEEAEASLEHEEGK 1561

Query: 1561 ILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHTRVVETMQSTLDAEIRSRNDALRVKKK 1620
            ILRIQLELNQVKSE+DRKIAEKDEE+DQLKRNH RVVE+MQSTLDAEIRSRNDALR+KKK
Sbjct: 1562 ILRIQLELNQVKSEIDRKIAEKDEELDQLKRNHLRVVESMQSTLDAEIRSRNDALRIKKK 1621

Query: 1621 MEGDLNEMEIQLNHANRLAAESLRNYRNTQGILKETQLHLDDALRGQEDLKEQLAIVERR 1680
            MEGDLNEMEIQLNHANR AAE+LRN RNTQGILK+TQLHLDDA+RGQ+DLKEQLA+VERR
Sbjct: 1622 MEGDLNEMEIQLNHANRQAAEALRNLRNTQGILKDTQLHLDDAIRGQDDLKEQLAMVERR 1681

Query: 1681 ANLLQAEIEELWATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQL 1740
            ANL+QAE+EEL A+LE+TER RK+AEQELLDASERVQLLHTQNTSLINTKKKLE D+SQ+
Sbjct: 1682 ANLMQAEVEELRASLERTERGRKMAEQELLDASERVQLLHTQNTSLINTKKKLETDISQI 1741

Query: 1741 QSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRL 1800
            Q E+E+++QE+RNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKN+EQTVKDLQ RL
Sbjct: 1742 QGEMEDIVQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRL 1801

Query: 1801 DEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHERRVKELTYQTEED 1860
            DEAEQLALKGGKKQIQKLEARVRELE EVE+EQK N EAVKGLRKHERRVKELTYQTEED
Sbjct: 1802 DEAEQLALKGGKKQIQKLEARVRELESEVESEQKHNVEAVKGLRKHERRVKELTYQTEED 1861

Query: 1861 RKNVLRLQDLVDKLQAKVKSYKRQAEEAEEQSNANLSKFRKLQHELEEAEERADIAESQV 1920
            RKN+LRLQDLVDKLQ KVK+YKRQAEEAEEQSN NL+KFRKLQHELEEA+ERADIAESQV
Sbjct: 1862 RKNILRLQDLVDKLQTKVKAYKRQAEEAEEQSNVNLAKFRKLQHELEEAKERADIAESQV 1921

Query: 1921 NKLRVKSREVHTKISAE 1937
            NKLRVKSREVHTK+ +E
Sbjct: 1922 NKLRVKSREVHTKVISE 1938


>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
            sapiens]
          Length = 1940

 Score = 3241 bits (8403), Expect = 0.0
 Identities = 1636/1926 (84%), Positives = 1798/1926 (93%)

Query: 4    SSDAEMAVFGEAAPYLRKSEKERIEAQNKPFDAKTSVFVAEPKESYVKSTIQSKEGGKVT 63
            SSD EM VFG AAP+LRKSEKERIEAQN+PFDAKT  FV + KE Y K  I+S + GKVT
Sbjct: 2    SSDTEMEVFGIAAPFLRKSEKERIEAQNQPFDAKTYCFVVDSKEEYAKGKIKSSQDGKVT 61

Query: 64   VKTEGGATLTVREDQVFPMNPPKYDKIEDMAMMTHLHEPGVLYNLKERYAAWMIYTYSGL 123
            V+TE   TL V+ + V+ MNPPK+D+IEDMAM+THL+EP VLYNLK+RY +WMIYTYSGL
Sbjct: 62   VETEDNRTLVVKPEDVYAMNPPKFDRIEDMAMLTHLNEPAVLYNLKDRYTSWMIYTYSGL 121

Query: 124  FCVTVNPYKWLPVYKPEVVAAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGES 183
            FCVTVNPYKWLPVY PEVV  YRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGES
Sbjct: 122  FCVTVNPYKWLPVYNPEVVEGYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGES 181

Query: 184  GAGKTVNTKRVIQYFATIAVTGEKKKDESGKMQGTLEDQIISANPLLEAFGNAKTVRNDN 243
            GAGKTVNTKRVIQYFATIA TG+  K +  KM+GTLEDQIISANPLLEAFGNAKTVRNDN
Sbjct: 182  GAGKTVNTKRVIQYFATIAATGDLAKKKDSKMKGTLEDQIISANPLLEAFGNAKTVRNDN 241

Query: 244  SSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQITSNKKPDLIEM 303
            SSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQI SNKKP+LIE+
Sbjct: 242  SSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQILSNKKPELIEL 301

Query: 304  LLITTNPYDYAFVSQGEITVPSIDDQEELMATDSAIDILGFTPEEKVSIYKLTGAVMHYG 363
            LLITTNPYDY F+SQGEI V SIDD EEL+ATDSAIDILGFTPEEK  +YKLTGAVMHYG
Sbjct: 302  LLITTNPYDYPFISQGEILVASIDDAEELLATDSAIDILGFTPEEKSGLYKLTGAVMHYG 361

Query: 364  NMKFKQKQREEQAEPDGTEVADKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTVQQV 423
            NMKFKQKQREEQAEPDGTEVADK AYL  LNS+DLLKALC+PRVKVGNEYVTKGQTV QV
Sbjct: 362  NMKFKQKQREEQAEPDGTEVADKTAYLMGLNSSDLLKALCFPRVKVGNEYVTKGQTVDQV 421

Query: 424  YNAVGALAKAVYEKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINF 483
            ++AV AL+K+VYEK+FLWMVTRINQQLDTK PRQ+FIGVLDIAGFEIF++NSLEQLCINF
Sbjct: 422  HHAVNALSKSVYEKLFLWMVTRINQQLDTKLPRQHFIGVLDIAGFEIFEYNSLEQLCINF 481

Query: 484  TNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPLGIFSILEEECMF 543
            TNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKP+GIFSILEEECMF
Sbjct: 482  TNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEECMF 541

Query: 544  PKATDTSFKNKLYDQHLGKSANFQKPKVVKGKAEAHFSLIHYAGTVDYNITGWLDKNKDP 603
            PKATDTSFKNKLYDQHLGKS NFQKPKVVKG+AEAHFSLIHYAGTVDY+++GWL+KNKDP
Sbjct: 542  PKATDTSFKNKLYDQHLGKSNNFQKPKVVKGRAEAHFSLIHYAGTVDYSVSGWLEKNKDP 601

Query: 604  LNDTVVGLYQKSAMKTLASLFSTYASAEADSSAKKGAKKKGSSFQTVSALFRENLNKLMT 663
            LN+TVVGLYQKS+ + LA L++T+A+A+ADS  KK AKKKGSSFQTVSALFRENLNKLM+
Sbjct: 602  LNETVVGLYQKSSNRLLAHLYATFATADADSGKKKVAKKKGSSFQTVSALFRENLNKLMS 661

Query: 664  NLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYGDFKQ 723
            NLR+THPHFVRCIIPNETKTPGAMEH LVLHQLRCNGVLEGIRICRKGFP+RILYGDFKQ
Sbjct: 662  NLRTTHPHFVRCIIPNETKTPGAMEHSLVLHQLRCNGVLEGIRICRKGFPNRILYGDFKQ 721

Query: 724  RYKVLNASAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDEK 783
            RY+VLNASAIPEGQFIDSKKA EKLLASIDIDHTQYKFGHTKVFFKAGLLG LEEMRD++
Sbjct: 722  RYRVLNASAIPEGQFIDSKKACEKLLASIDIDHTQYKFGHTKVFFKAGLLGTLEEMRDDR 781

Query: 784  LAQIITRTQAVCRGFLMRVEYQKMLQRREALFCIQYNVRAFMNVKHWPWMKLFFKIKPLL 843
            LA++ITRTQAVCRGFLMRVE+QKM+QRRE++FCIQYN+R+FMNVKHWPWMKLFFKIKPLL
Sbjct: 782  LAKLITRTQAVCRGFLMRVEFQKMVQRRESIFCIQYNIRSFMNVKHWPWMKLFFKIKPLL 841

Query: 844  KSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLAD 903
            KSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEK+VTL++EKNDLQLQVQ+E+++L D
Sbjct: 842  KSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLD 901

Query: 904  AEERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLELT 963
            AEERC+QLIK K QLEAKIKEVTERAE+EEEINAELTAKKRKLEDECSELKKDIDDLELT
Sbjct: 902  AEERCDQLIKAKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELT 961

Query: 964  LAKVEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDKVNIL 1023
            LAKVEKEKHATENKVKNLTEE++GLDETIAKL++EKKALQE HQQ LDDLQAEEDKVN L
Sbjct: 962  LAKVEKEKHATENKVKNLTEELSGLDETIAKLTREKKALQEAHQQALDDLQAEEDKVNSL 1021

Query: 1024 TKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQLDEKL 1083
             K K+KLEQQV+DLE SLEQEKKLR+DLER KRKLEGDLKLAQES +D+ENDKQQLDE+L
Sbjct: 1022 NKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDERL 1081

Query: 1084 EKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQRSDLS 1143
            +KK+FE   L SK+EDEQ + +Q QKKIKELQARIEEL EEIEAERA+RAK EKQRSD +
Sbjct: 1082 KKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYA 1141

Query: 1144 RELEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRKKHADSM 1203
            RELEE+SERLEEAGG TS Q+ELNKKREAEF KLRRDLEEATLQHEAMVAALRKKHADS+
Sbjct: 1142 RELEELSERLEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEAMVAALRKKHADSV 1201

Query: 1204 AELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGNLEKMCRSLEDQVSELK 1263
            AELGEQIDNLQRVKQKLEKEKSE K+E DDLSS+ E++SK+K NLEK+CR+LEDQ+SE +
Sbjct: 1202 AELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEAR 1261

Query: 1264 TKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKHQLE 1323
             K EE QR +++LT Q++RLQTEAGE SRQL+EK+++VSQLSRSKQA TQQ EELK QLE
Sbjct: 1262 GKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLE 1321

Query: 1324 EETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAI 1383
            EE KAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAI
Sbjct: 1322 EENKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAI 1381

Query: 1384 QRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACA 1443
            QRTEELEEAKKKLAQRLQ++EE VEAVNAKCASLEKTKQRLQ EVEDLM+DVER+N+  A
Sbjct: 1382 QRTEELEEAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANSLAA 1441

Query: 1444 ALDKKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELFKVKNVYEESLDQLETLRR 1503
            ALDKKQRNFDKVL+EWK K EE+QAELEAS KESRSLSTELFK+KN YEE+LDQLET++R
Sbjct: 1442 ALDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQLETVKR 1501

Query: 1504 ENKNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILR 1563
            ENKNL+QEI+DLTEQIAE GK IHELEK +KQ+E EK +IQ ALEEAEA+LEHEE KILR
Sbjct: 1502 ENKNLEQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQLALEEAEAALEHEEAKILR 1561

Query: 1564 IQLELNQVKSEVDRKIAEKDEEIDQLKRNHTRVVETMQSTLDAEIRSRNDALRVKKKMEG 1623
            IQLEL QVKSE+DRKIAEKDEEI+QLKRN+ R VETMQS LDAE+RSRN+A+R+KKKMEG
Sbjct: 1562 IQLELTQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSALDAEVRSRNEAIRLKKKMEG 1621

Query: 1624 DLNEMEIQLNHANRLAAESLRNYRNTQGILKETQLHLDDALRGQEDLKEQLAIVERRANL 1683
            DLNE+EIQL+HANR AAE+L++ R+ QG LK+TQLHLDDALRGQEDLKEQLAIVERRANL
Sbjct: 1622 DLNEIEIQLSHANRQAAETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANL 1681

Query: 1684 LQAEIEELWATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQLQSE 1743
            LQAE+EEL ATLEQTER+RK+AEQELLD++ERVQLLHTQNTSLI+TKKKLE D+ QLQSE
Sbjct: 1682 LQAEVEELRATLEQTERARKLAEQELLDSNERVQLLHTQNTSLIHTKKKLETDLMQLQSE 1741

Query: 1744 VEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEA 1803
            VE+  +++RNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEA
Sbjct: 1742 VEDASRDARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEA 1801

Query: 1804 EQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHERRVKELTYQTEEDRKN 1863
            EQLALKGGKKQIQKLE R+RELE E+E EQK+N E+VKGLRK+ERRVKELTYQ+EEDRKN
Sbjct: 1802 EQLALKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLRKYERRVKELTYQSEEDRKN 1861

Query: 1864 VLRLQDLVDKLQAKVKSYKRQAEEAEEQSNANLSKFRKLQHELEEAEERADIAESQVNKL 1923
            VLRLQDLVDKLQ KVKSYKRQAEEA+EQ+NA+L+KFRK QHELEEAEERADIAESQVNKL
Sbjct: 1862 VLRLQDLVDKLQVKVKSYKRQAEEADEQANAHLTKFRKAQHELEEAEERADIAESQVNKL 1921

Query: 1924 RVKSRE 1929
            R K+R+
Sbjct: 1922 RAKTRD 1927



 Score =  228 bits (581), Expect = 4e-59
 Identities = 228/973 (23%), Positives = 428/973 (43%), Gaps = 112/973 (11%)

Query: 993  AKLSKEKKALQETHQQTLDDLQAEEDKVNILTKAKTKLEQQVDDLEGSLEQEKKLRMDLE 1052
            A+  KE   ++E  Q+T D+L   E K   L +    L Q+ +DL+  ++ E        
Sbjct: 844  AETEKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAES------- 896

Query: 1053 RAKRKLEGDLKLAQESTMDMENDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIK 1112
                          E+ +D E    QL +   + E +I  +  + EDE+ +  +L  K +
Sbjct: 897  --------------ENLLDAEERCDQLIKAKFQLEAKIKEVTERAEDEEEINAELTAKKR 942

Query: 1113 ELQARIEELGEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQVELNKKREA 1172
            +L+    EL ++I+    + AK EK++     +++ ++E L    G      +L ++++A
Sbjct: 943  KLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEELS---GLDETIAKLTREKKA 999

Query: 1173 EFQKLRRDLEEATLQHEAMVAALRKKHADSMAELGEQIDNLQRVKQKLEKEKSELKMETD 1232
                                  L++ H  ++ +L  + D +      L K KS+L+ + +
Sbjct: 1000 ----------------------LQEAHQQALDDLQAEEDKVN----SLNKTKSKLEQQVE 1033

Query: 1233 DLSSNAEAISKAKGNLEKMCRSLEDQVSELKTKEEEQQRLINDLTAQRARLQTEAGEYSR 1292
            DL S+ E   K + +LE+  R LE    +LK  +E    L ND      RL+ +  EY  
Sbjct: 1034 DLESSLEQEKKLRVDLERNKRKLE---GDLKLAQESILDLENDKQQLDERLKKKDFEYC- 1089

Query: 1293 QLDEKDALVSQLSRSKQASTQQIEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEE 1352
            QL  K      L    Q   ++++    +LEEE +A+ A     +  R D     E+  E
Sbjct: 1090 QLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSE 1149

Query: 1353 EQE---GKAELQRALSKAN-SEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEHVE 1408
              E   G    Q  L+K   +E  + R   E   +Q    +   +KK A  + E  E ++
Sbjct: 1150 RLEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEAMVAALRKKHADSVAELGEQID 1209

Query: 1409 AVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQA 1468
             +      LEK K   + E++DL   +E  + + A L+K  R  +  LSE + K EE Q 
Sbjct: 1210 NLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQR 1269

Query: 1469 ELEASQKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEISDLTEQIAEGGK---- 1524
             L     +   L TE  ++    EE    +  L R  +   Q+  +L  Q+ E  K    
Sbjct: 1270 SLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENKAKNA 1329

Query: 1525 -------QIHELEKIKKQVEQE---KCEIQAALEEAEASLEHEEGKILRIQLELNQVKSE 1574
                     H+ + +++Q E+E   K E+Q AL +A +              E+ Q +++
Sbjct: 1330 LAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANS--------------EVAQWRTK 1375

Query: 1575 VDRKIAEKDEEIDQLKRNHTRVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEMEIQLNH 1634
             +    ++ EE+++ K+   + ++  +  ++A         + K++++G++ ++ + +  
Sbjct: 1376 YETDAIQRTEELEEAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVER 1435

Query: 1635 ANRLAAESLRNYRNTQGILKETQLHLDDALRGQE-DLKEQLAIVERRANLLQAEIEELWA 1693
            AN LAA   +  RN   +L E +   +++    E  LKE  ++      L  A  EE   
Sbjct: 1436 ANSLAAALDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLSTELFKLKNA-YEEALD 1494

Query: 1694 TLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQESRN 1753
             LE  +R  K  EQE+ D +E++         L  ++K++E + + +Q  +EE      +
Sbjct: 1495 QLETVKRENKNLEQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQLALEEAEAALEH 1554

Query: 1754 AEEKAKKAITDAAMMAEEL-KKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGK 1812
             E K  +   +   +  E+ +K  +    +E++K+N ++TV+ +Q  LD AE  +     
Sbjct: 1555 EEAKILRIQLELTQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSALD-AEVRSRNEAI 1613

Query: 1813 KQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHERRVKEL------TYQTEEDRKNVLR 1866
            +  +K+E  + E+E ++ +  ++ AE +K LR  + ++K+         + +ED K  L 
Sbjct: 1614 RLKKKMEGDLNEIEIQLSHANRQAAETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLA 1673

Query: 1867 L-QDLVDKLQAKVKSYKRQAEEAEEQSNANLSKFRKL-QHELEEAEERADIAESQVNKLR 1924
            + +   + LQA+V+  +   E+ E        + RKL + EL ++ ER  +  +Q   L 
Sbjct: 1674 IVERRANLLQAEVEELRATLEQTE--------RARKLAEQELLDSNERVQLLHTQNTSL- 1724

Query: 1925 VKSREVHTKISAE 1937
                 +HTK   E
Sbjct: 1725 -----IHTKKKLE 1732



 Score = 84.3 bits (207), Expect = 1e-15
 Identities = 86/346 (24%), Positives = 152/346 (43%), Gaps = 48/346 (13%)

Query: 844  KSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLAD 903
            ++AET K + +++ + + T+  L  +   +++L+E++  + +  N LQ +V+ E  +  +
Sbjct: 1636 QAAETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEVE-ELRATLE 1694

Query: 904  AEERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLELT 963
              ER  +L       E ++ +  ER +     N  L   K+KLE +  +L+ +++D    
Sbjct: 1695 QTERARKLA------EQELLDSNERVQLLHTQNTSLIHTKKKLETDLMQLQSEVEDASRD 1748

Query: 964  LAKVEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDKVNIL 1023
                E++          + EE+    +T A L + KK L+    QT+ DLQ   D+   L
Sbjct: 1749 ARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLE----QTVKDLQHRLDEAEQL 1804

Query: 1024 T-----KAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQ 1078
                  K   KLE ++ +LE  LE E+K   +  +  RK E  +K   E T   E D+  
Sbjct: 1805 ALKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLRKYERRVK---ELTYQSEEDR-- 1859

Query: 1079 LDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQ 1138
                  K    + +L+ K          LQ K+K  + + EE  E+  A      KA+  
Sbjct: 1860 ------KNVLRLQDLVDK----------LQVKVKSYKRQAEEADEQANAHLTKFRKAQ-- 1901

Query: 1139 RSDLSRELEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEA 1184
                  ELEE  ER + A     +QV   + +  +F   R  + E+
Sbjct: 1902 -----HELEEAEERADIA----ESQVNKLRAKTRDFTSSRMVVHES 1938



 Score = 52.0 bits (123), Expect = 6e-06
 Identities = 53/218 (24%), Positives = 92/218 (42%), Gaps = 37/218 (16%)

Query: 1757 KAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTV-------KDLQHRLDEAEQLALK 1809
            K+ +   + A M EE +K +D  A  E  +K LE+ +        DLQ ++    +  L 
Sbjct: 842  KSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLD 901

Query: 1810 GGKKQIQ------KLEARVRELEGEVENEQKRNAEAVKGLRKHERRVKEL---------- 1853
              ++  Q      +LEA+++E+    E+E++ NAE     RK E    EL          
Sbjct: 902  AEERCDQLIKAKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELT 961

Query: 1854 -------TYQTEEDRKNVLRLQDLVDKLQAKVKSYKRQAEEAEEQSNANL-------SKF 1899
                    + TE   KN+      +D+  AK+   K+  +EA +Q+  +L       +  
Sbjct: 962  LAKVEKEKHATENKVKNLTEELSGLDETIAKLTREKKALQEAHQQALDDLQAEEDKVNSL 1021

Query: 1900 RKLQHELEEAEERADIAESQVNKLRVKSREVHTKISAE 1937
             K + +LE+  E  + +  Q  KLRV       K+  +
Sbjct: 1022 NKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGD 1059


>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
            sapiens]
          Length = 1938

 Score = 3138 bits (8137), Expect = 0.0
 Identities = 1582/1930 (81%), Positives = 1752/1930 (90%), Gaps = 3/1930 (0%)

Query: 4    SSDAEMAVFGEAAPYLRKSEKERIEAQNKPFDAKTSVFVAEPKESYVKSTIQSKEGGKVT 63
            SSDAEMA+FGEAAPYLRK EKERIEAQN+PFD+K + FVA+ KE YVK  IQ++E  KV 
Sbjct: 2    SSDAEMAIFGEAAPYLRKPEKERIEAQNRPFDSKKACFVADNKEMYVKGMIQTRENDKVI 61

Query: 64   VKTEGGATLTVREDQVFPMNPPKYDKIEDMAMMTHLHEPGVLYNLKERYAAWMIYTYSGL 123
            VKT     LT+  DQVFPMNPPK+DKIEDMAMMTHLHEP VLYNLKERYAAWMIYTYSGL
Sbjct: 62   VKTLDDRMLTLNNDQVFPMNPPKFDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGL 121

Query: 124  FCVTVNPYKWLPVYKPEVVAAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGES 183
            FCVTVNPYKWLPVYKPEVVAAYRGKKRQEAPPHIFSISDNAYQFMLTDR+NQSILITGES
Sbjct: 122  FCVTVNPYKWLPVYKPEVVAAYRGKKRQEAPPHIFSISDNAYQFMLTDRDNQSILITGES 181

Query: 184  GAGKTVNTKRVIQYFATIAVTGEKKKD-ESGKMQGTLEDQIISANPLLEAFGNAKTVRND 242
            GAGKTVNTKRVIQYFATIAVTG+KKK+ + GKMQGTLEDQII ANPLLEAFGNAKTVRND
Sbjct: 182  GAGKTVNTKRVIQYFATIAVTGDKKKETQPGKMQGTLEDQIIQANPLLEAFGNAKTVRND 241

Query: 243  NSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQITSNKKPDLIE 302
            NSSRFGKFIRIHFG TGKLASADIETYLLEKSRVTFQL +ERSYHIFYQI SNKKP+LI+
Sbjct: 242  NSSRFGKFIRIHFGATGKLASADIETYLLEKSRVTFQLSSERSYHIFYQIMSNKKPELID 301

Query: 303  MLLITTNPYDYAFVSQGEITVPSIDDQEELMATDSAIDILGFTPEEKVSIYKLTGAVMHY 362
            +LLI+TNP+D+ FVSQGE+TV SIDD EEL+ATD+AIDILGF+ EEKV IYKLTGAVMHY
Sbjct: 302  LLLISTNPFDFPFVSQGEVTVASIDDSEELLATDNAIDILGFSSEEKVGIYKLTGAVMHY 361

Query: 363  GNMKFKQKQREEQAEPDGTEVADKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTVQQ 422
            GNMKFKQKQREEQAEPDGTEVADKA YL  LNSA++LK LC PRVKVGNEYVTKGQ VQQ
Sbjct: 362  GNMKFKQKQREEQAEPDGTEVADKAGYLMGLNSAEMLKGLCCPRVKVGNEYVTKGQNVQQ 421

Query: 423  VYNAVGALAKAVYEKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCIN 482
            V N+VGALAKAVYEKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCIN
Sbjct: 422  VTNSVGALAKAVYEKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCIN 481

Query: 483  FTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPLGIFSILEEECM 542
            FTNEKLQQFFNHHMFVLEQEEYKKEGIEW FIDFGMDLAACIELIEKP+GIFSILEEECM
Sbjct: 482  FTNEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLAACIELIEKPMGIFSILEEECM 541

Query: 543  FPKATDTSFKNKLYDQHLGKSANFQKPKVVKGKAEAHFSLIHYAGTVDYNITGWLDKNKD 602
            FPKATDTSFKNKLYDQHLGKS NFQKPK  KGKAEAHFSL+HYAGTVDYNI GWLDKNKD
Sbjct: 542  FPKATDTSFKNKLYDQHLGKSNNFQKPKPAKGKAEAHFSLVHYAGTVDYNIAGWLDKNKD 601

Query: 603  PLNDTVVGLYQKSAMKTLASLFSTYASAEADSS--AKKGAKKKGSSFQTVSALFRENLNK 660
            PLN+TVVGLYQKS++K L+ LFS YA AE   S  +KKG KKKGSSFQTVSA+FRENLNK
Sbjct: 602  PLNETVVGLYQKSSLKLLSFLFSNYAGAETGDSGGSKKGGKKKGSSFQTVSAVFRENLNK 661

Query: 661  LMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYGD 720
            LMTNLRSTHPHFVRC+IPNETKTPG M+H LV+HQLRCNGVLEGIRICRKGFPSRILY D
Sbjct: 662  LMTNLRSTHPHFVRCLIPNETKTPGVMDHYLVMHQLRCNGVLEGIRICRKGFPSRILYAD 721

Query: 721  FKQRYKVLNASAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMR 780
            FKQRY++LNASAIPEGQFIDSK ASEKLL SID+D  Q++FG+TKVFFKAGLLGLLEEMR
Sbjct: 722  FKQRYRILNASAIPEGQFIDSKNASEKLLNSIDVDREQFRFGNTKVFFKAGLLGLLEEMR 781

Query: 781  DEKLAQIITRTQAVCRGFLMRVEYQKMLQRREALFCIQYNVRAFMNVKHWPWMKLFFKIK 840
            DEKL  ++T TQAVCRG+LMRVE++KM++RR+++FCIQYN+R+FMNVKHWPWM LFFKIK
Sbjct: 782  DEKLVTLMTSTQAVCRGYLMRVEFKKMMERRDSIFCIQYNIRSFMNVKHWPWMNLFFKIK 841

Query: 841  PLLKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADS 900
            PLLKSAE EKEMATMKE+F++TK+ELA+SEA+RKELEEKMV+LL+EKNDLQLQVQSE ++
Sbjct: 842  PLLKSAEAEKEMATMKEDFERTKEELARSEARRKELEEKMVSLLQEKNDLQLQVQSETEN 901

Query: 901  LADAEERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDL 960
            L DAEERCE LIK+KI LEAK+KE+TER EEEEE+N+EL AKKR LED+CS LK+DIDDL
Sbjct: 902  LMDAEERCEGLIKSKILLEAKVKELTERLEEEEEMNSELVAKKRNLEDKCSSLKRDIDDL 961

Query: 961  ELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDKV 1020
            ELTL KVEKEKHATENKVKNL+EEM  L+E I+KL+KEKK+LQE HQQTLDDLQ EEDKV
Sbjct: 962  ELTLTKVEKEKHATENKVKNLSEEMTALEENISKLTKEKKSLQEAHQQTLDDLQVEEDKV 1021

Query: 1021 NILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQLD 1080
            N L K   KLEQQ DDLEGSLEQEKKLR DLERAKRKLEGDLK++QES MD+ENDKQQ++
Sbjct: 1022 NGLIKINAKLEQQTDDLEGSLEQEKKLRADLERAKRKLEGDLKMSQESIMDLENDKQQIE 1081

Query: 1081 EKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQRS 1140
            EKL+KKEFE+S L +KI+DEQ   +Q QKKIKELQARIEEL EEIEAE   RAK EKQRS
Sbjct: 1082 EKLKKKEFELSQLQAKIDDEQVHSLQFQKKIKELQARIEELEEEIEAEHTLRAKIEKQRS 1141

Query: 1141 DLSRELEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRKKHA 1200
            DL+RELEEISERLEEA GATSAQ+E+NKKREAEFQK+RRDLEEATLQHEA  A LRKK A
Sbjct: 1142 DLARELEEISERLEEASGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKQA 1201

Query: 1201 DSMAELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGNLEKMCRSLEDQVS 1260
            DS+AELGEQIDNLQRVKQKLEKEKSELKME DD++SN EA+SK+K N+E+ CR++EDQ S
Sbjct: 1202 DSVAELGEQIDNLQRVKQKLEKEKSELKMEIDDMASNIEALSKSKSNIERTCRTVEDQFS 1261

Query: 1261 ELKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKH 1320
            E+K K+E+Q +LI+DL  Q+ARLQT+ GE S +++EK++L+SQL++SKQA TQQ+EELK 
Sbjct: 1262 EIKAKDEQQTQLIHDLNMQKARLQTQNGELSHRVEEKESLISQLTKSKQALTQQLEELKR 1321

Query: 1321 QLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYET 1380
            Q+EEETKAKNA+AHALQSSRHDCDLLREQYEEEQE KAELQRALSKANSEVAQWRTKYET
Sbjct: 1322 QMEEETKAKNAMAHALQSSRHDCDLLREQYEEEQEAKAELQRALSKANSEVAQWRTKYET 1381

Query: 1381 DAIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNA 1440
            DAIQRTEELEEAKKKLAQRLQEAEE+ E  N+KCASLEKTKQRLQ EVEDLM D+ERS+ 
Sbjct: 1382 DAIQRTEELEEAKKKLAQRLQEAEENTETANSKCASLEKTKQRLQGEVEDLMRDLERSHT 1441

Query: 1441 ACAALDKKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELFKVKNVYEESLDQLET 1500
            ACA LDKKQRNFDKVL+EWKQK +E+QAELEA+QKESRSLSTELFK++N YEE +DQLET
Sbjct: 1442 ACATLDKKQRNFDKVLAEWKQKLDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQLET 1501

Query: 1501 LRRENKNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGK 1560
            LRRENKNLQ+EISDLTEQIAE GK + E EK KK VEQEK ++Q ALEE E SLEHEE K
Sbjct: 1502 LRRENKNLQEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEESK 1561

Query: 1561 ILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHTRVVETMQSTLDAEIRSRNDALRVKKK 1620
            ILR+QLEL+QVKSE+DRK+ EKDEEI+QLKRN  R  E +QS LDAEIRSRNDALR+KKK
Sbjct: 1562 ILRVQLELSQVKSELDRKVIEKDEEIEQLKRNSQRAAEALQSVLDAEIRSRNDALRLKKK 1621

Query: 1621 MEGDLNEMEIQLNHANRLAAESLRNYRNTQGILKETQLHLDDALRGQEDLKEQLAIVERR 1680
            MEGDLNEMEIQL H+NR  AE+ ++ R  QG LK++QLHLDDALR  EDLKEQLAIVERR
Sbjct: 1622 MEGDLNEMEIQLGHSNRQMAETQKHLRTVQGQLKDSQLHLDDALRSNEDLKEQLAIVERR 1681

Query: 1681 ANLLQAEIEELWATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQL 1740
              LL  E+EE+   LEQTER+R+++EQELLDAS+RVQLLH+QNTSLINTKKKLE D++Q 
Sbjct: 1682 NGLLLEELEEMKVALEQTERTRRLSEQELLDASDRVQLLHSQNTSLINTKKKLEADIAQC 1741

Query: 1741 QSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRL 1800
            Q+EVE  IQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRL
Sbjct: 1742 QAEVENSIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRL 1801

Query: 1801 DEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHERRVKELTYQTEED 1860
            DEAEQLALKGGKKQIQKLE RVRELE E++ EQKR AEA+KG  K+ER+VKE+TYQ EED
Sbjct: 1802 DEAEQLALKGGKKQIQKLENRVRELENELDVEQKRGAEALKGAHKYERKVKEMTYQAEED 1861

Query: 1861 RKNVLRLQDLVDKLQAKVKSYKRQAEEAEEQSNANLSKFRKLQHELEEAEERADIAESQV 1920
             KN+LRLQDLVDKLQAKVKSYKRQAEEAEEQ+N  LS+ R++QHELEEA ERADIAESQV
Sbjct: 1862 HKNILRLQDLVDKLQAKVKSYKRQAEEAEEQANTQLSRCRRVQHELEEAAERADIAESQV 1921

Query: 1921 NKLRVKSREV 1930
            NKLR KSR+V
Sbjct: 1922 NKLRAKSRDV 1931



 Score =  164 bits (414), Expect = 1e-39
 Identities = 161/812 (19%), Positives = 347/812 (42%), Gaps = 92/812 (11%)

Query: 1133 AKAEKQRSDLSRELEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQHEAMV 1192
            A+AEK+ + +  + E   E L                  A  +  R++LEE       MV
Sbjct: 847  AEAEKEMATMKEDFERTKEEL------------------ARSEARRKELEEK------MV 882

Query: 1193 AALRKKHADSMAELGEQIDNLQRVKQKLE---KEKSELKMETDDLSSNAEAISKAKGNLE 1249
            + L++K+ D   ++  + +NL   +++ E   K K  L+ +  +L+   E   +    L 
Sbjct: 883  SLLQEKN-DLQLQVQSETENLMDAEERCEGLIKSKILLEAKVKELTERLEEEEEMNSELV 941

Query: 1250 KMCRSLEDQVSELKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQ 1309
               R+LED+ S LK   ++ +  +  +  ++   + +    S ++   +  +S+L++ K+
Sbjct: 942  AKKRNLEDKCSSLKRDIDDLELTLTKVEKEKHATENKVKNLSEEMTALEENISKLTKEKK 1001

Query: 1310 ASTQQIEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANS 1369
            +  +  ++    L+ E    N L           D L    E+E++ +A+L+RA  K   
Sbjct: 1002 SLQEAHQQTLDDLQVEEDKVNGLIKINAKLEQQTDDLEGSLEQEKKLRADLERAKRKLEG 1061

Query: 1370 EVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVE 1429
            ++   +     D     +++EE  KK    L + +  ++         +K  + LQ  +E
Sbjct: 1062 DLKMSQESI-MDLENDKQQIEEKLKKKEFELSQLQAKIDDEQVHSLQFQKKIKELQARIE 1120

Query: 1430 DLMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELFKVKN 1489
            +L  ++E  +   A ++K++ +  + L E  ++ EE      A  + ++    E  K++ 
Sbjct: 1121 ELEEEIEAEHTLRAKIEKQRSDLARELEEISERLEEASGATSAQIEMNKKREAEFQKMRR 1180

Query: 1490 VYEESLDQLETLRRENKNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALEE 1549
              EE+  Q E      +  Q       + +AE G+QI  L+++K+++E+EK E++  +++
Sbjct: 1181 DLEEATLQHEATAATLRKKQ------ADSVAELGEQIDNLQRVKQKLEKEKSELKMEIDD 1234

Query: 1550 AEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHTRVVETMQSTLDAEIR 1609
              +++E            L++ KS ++R     +++  ++K    +  + +         
Sbjct: 1235 MASNIE-----------ALSKSKSNIERTCRTVEDQFSEIKAKDEQQTQLI--------- 1274

Query: 1610 SRNDALRVKKKMEGDLNEMEIQLNHANRLAAESLRNYRNTQGILKETQLHLDDALRGQED 1669
              +D    K +++    E+  ++     L ++  ++ +     L+E +  +++  + +  
Sbjct: 1275 --HDLNMQKARLQTQNGELSHRVEEKESLISQLTKSKQALTQQLEELKRQMEEETKAKNA 1332

Query: 1670 LKEQLAIVERRANLLQAEIEELWATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINT 1729
            +   L       +LL+ + EE               EQE    +E  + L   N+ +   
Sbjct: 1333 MAHALQSSRHDCDLLREQYEE---------------EQEA--KAELQRALSKANSEVAQW 1375

Query: 1730 KKKLENDVSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTS-AHLERMKKN 1788
            + K E D  Q   E+EE           AKK +      AEE  +  ++  A LE+ K+ 
Sbjct: 1376 RTKYETDAIQRTEELEE-----------AKKKLAQRLQEAEENTETANSKCASLEKTKQR 1424

Query: 1789 LEQTVKDLQHRLDEAEQLALKGGKKQ------IQKLEARVRELEGEVENEQKRNAEAVKG 1842
            L+  V+DL   L+ +        KKQ      + + + ++ E + E+E  QK +      
Sbjct: 1425 LQGEVEDLMRDLERSHTACATLDKKQRNFDKVLAEWKQKLDESQAELEAAQKESRSLSTE 1484

Query: 1843 LRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQAKVKSYKRQAEEAEEQSNANLSKFRKL 1902
            L K     +E+  Q E  R+    LQ+ +  L  ++    +  +EAE+       +   L
Sbjct: 1485 LFKMRNAYEEVVDQLETLRRENKNLQEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDL 1544

Query: 1903 QHELEEAEERADIAESQVNKLRVKSREVHTKI 1934
            Q  LEE E   +  ES++ +++++  +V +++
Sbjct: 1545 QVALEEVEGSLEHEESKILRVQLELSQVKSEL 1576



 Score = 74.3 bits (181), Expect = 1e-12
 Identities = 76/319 (23%), Positives = 151/319 (47%), Gaps = 37/319 (11%)

Query: 846  AETEKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLADAE 905
            AET+K + T++ + + ++  L  +    ++L+E++  +++ +N L L+   E     +  
Sbjct: 1641 AETQKHLRTVQGQLKDSQLHLDDALRSNEDLKEQLA-IVERRNGLLLEELEEMKVALEQT 1699

Query: 906  ERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLELTLA 965
            ER  +L       E ++ + ++R +     N  L   K+KLE + ++ + ++++      
Sbjct: 1700 ERTRRLS------EQELLDASDRVQLLHSQNTSLINTKKKLEADIAQCQAEVEN------ 1747

Query: 966  KVEKEKHATENKVKNLT------EEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDK 1019
             +++ ++A E   K +T      EE+    +T A L + KK L+    QT+ DLQ   D+
Sbjct: 1748 SIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLE----QTVKDLQHRLDE 1803

Query: 1020 VNILT-----KAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMEN 1074
               L      K   KLE +V +LE  L+ E+K   +  +   K E  +K   E T   E 
Sbjct: 1804 AEQLALKGGKKQIQKLENRVRELENELDVEQKRGAEALKGAHKYERKVK---EMTYQAEE 1860

Query: 1075 DKQ---QLDEKLEKKEFEISNLISKIED-EQAVEIQLQKKIKELQARIEELGEEIE-AER 1129
            D +   +L + ++K + ++ +   + E+ E+    QL  + + +Q  +EE  E  + AE 
Sbjct: 1861 DHKNILRLQDLVDKLQAKVKSYKRQAEEAEEQANTQL-SRCRRVQHELEEAAERADIAES 1919

Query: 1130 ASRAKAEKQRSDLSRELEE 1148
                   K R   S+++EE
Sbjct: 1920 QVNKLRAKSRDVGSQKMEE 1938



 Score = 69.3 bits (168), Expect = 3e-11
 Identities = 68/315 (21%), Positives = 147/315 (46%), Gaps = 30/315 (9%)

Query: 1639 AAESLRNYRNTQGILKETQLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELWATLEQT 1698
            +AE+ +     +   + T+  L  +   +++L+E++  + +  N LQ +++     L   
Sbjct: 846  SAEAEKEMATMKEDFERTKEELARSEARRKELEEKMVSLLQEKNDLQLQVQSETENLMDA 905

Query: 1699 E-------RSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQES 1751
            E       +S+ + E ++ + +ER++     N+ L+  K+ LE+  S L+ +++++    
Sbjct: 906  EERCEGLIKSKILLEAKVKELTERLEEEEEMNSELVAKKRNLEDKCSSLKRDIDDLELTL 965

Query: 1752 RNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLE----QTVKDLQHRLDEAEQLA 1807
               E++          ++EE+   ++  + L + KK+L+    QT+ DLQ   D+   L 
Sbjct: 966  TKVEKEKHATENKVKNLSEEMTALEENISKLTKEKKSLQEAHQQTLDDLQVEEDKVNGLI 1025

Query: 1808 LKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNVLRL 1867
                 K   KLE +  +LEG +E E+K  A+  +  RK E  +K         +++++ L
Sbjct: 1026 -----KINAKLEQQTDDLEGSLEQEKKLRADLERAKRKLEGDLKM-------SQESIMDL 1073

Query: 1868 QDLVDKLQAKVKSYKRQAEEAEEQSNANLSKFRKLQ-----HELEEAEERADIAESQVNK 1922
            ++  DK Q + K  K++ E ++ Q+  +  +   LQ      EL+   E  +      + 
Sbjct: 1074 EN--DKQQIEEKLKKKEFELSQLQAKIDDEQVHSLQFQKKIKELQARIEELEEEIEAEHT 1131

Query: 1923 LRVKSREVHTKISAE 1937
            LR K  +  + ++ E
Sbjct: 1132 LRAKIEKQRSDLARE 1146


>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
            sapiens]
          Length = 1935

 Score = 3114 bits (8074), Expect = 0.0
 Identities = 1559/1928 (80%), Positives = 1750/1928 (90%)

Query: 6    DAEMAVFGEAAPYLRKSEKERIEAQNKPFDAKTSVFVAEPKESYVKSTIQSKEGGKVTVK 65
            D+EMAVFG AAPYLRKSEKER+EAQ +PFD K  VFV + K+ +VK+ I S+EGGKVT +
Sbjct: 3    DSEMAVFGAAAPYLRKSEKERLEAQTRPFDLKKDVFVPDDKQEFVKAKIVSREGGKVTAE 62

Query: 66   TEGGATLTVREDQVFPMNPPKYDKIEDMAMMTHLHEPGVLYNLKERYAAWMIYTYSGLFC 125
            TE G T+TV+EDQV   NPPK+DKIEDMAM+T LHEP VLYNLK+RY +WMIYTYSGLFC
Sbjct: 63   TEYGKTVTVKEDQVMQQNPPKFDKIEDMAMLTFLHEPAVLYNLKDRYGSWMIYTYSGLFC 122

Query: 126  VTVNPYKWLPVYKPEVVAAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGA 185
            VTVNPYKWLPVY PEVVAAYRGKKR EAPPHIFSISDNAYQ+MLTDRENQSILITGESGA
Sbjct: 123  VTVNPYKWLPVYTPEVVAAYRGKKRSEAPPHIFSISDNAYQYMLTDRENQSILITGESGA 182

Query: 186  GKTVNTKRVIQYFATIAVTGEKKKDESGKMQGTLEDQIISANPLLEAFGNAKTVRNDNSS 245
            GKTVNTKRVIQYFA IA  G++ K +    +GTLEDQII ANP LEAFGNAKTVRNDNSS
Sbjct: 183  GKTVNTKRVIQYFAVIAAIGDRSKKDQSPGKGTLEDQIIQANPALEAFGNAKTVRNDNSS 242

Query: 246  RFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQITSNKKPDLIEMLL 305
            RFGKFIRIHFG TGKLASADIETYLLEKSRV FQLKAER YHIFYQI SNKKP+L++MLL
Sbjct: 243  RFGKFIRIHFGATGKLASADIETYLLEKSRVIFQLKAERDYHIFYQILSNKKPELLDMLL 302

Query: 306  ITTNPYDYAFVSQGEITVPSIDDQEELMATDSAIDILGFTPEEKVSIYKLTGAVMHYGNM 365
            IT NPYDYAF+SQGE TV SIDD EELMATD+A D+LGFT EEK S+YKLTGA+MH+GNM
Sbjct: 303  ITNNPYDYAFISQGETTVASIDDAEELMATDNAFDVLGFTSEEKNSMYKLTGAIMHFGNM 362

Query: 366  KFKQKQREEQAEPDGTEVADKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTVQQVYN 425
            KFK KQREEQAEPDGTE ADK+AYL  LNSADLLK LC+PRVKVGNEYVTKGQ VQQV  
Sbjct: 363  KFKLKQREEQAEPDGTEEADKSAYLMGLNSADLLKGLCHPRVKVGNEYVTKGQNVQQVIY 422

Query: 426  AVGALAKAVYEKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTN 485
            A GALAKAVYE+MF WMVTRIN  L+TKQPRQYFIGVLDIAGFEIFDFNS EQLCINFTN
Sbjct: 423  ATGALAKAVYERMFNWMVTRINATLETKQPRQYFIGVLDIAGFEIFDFNSFEQLCINFTN 482

Query: 486  EKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPLGIFSILEEECMFPK 545
            EKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDL ACI+LIEKP+GI SILEEECMFPK
Sbjct: 483  EKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLQACIDLIEKPMGIMSILEEECMFPK 542

Query: 546  ATDTSFKNKLYDQHLGKSANFQKPKVVKGKAEAHFSLIHYAGTVDYNITGWLDKNKDPLN 605
            ATD +FK KL+D HLGKSANFQKP+ +KGK EAHFSLIHYAG VDYNI GWL KNKDPLN
Sbjct: 543  ATDMTFKAKLFDNHLGKSANFQKPRNIKGKPEAHFSLIHYAGIVDYNIIGWLQKNKDPLN 602

Query: 606  DTVVGLYQKSAMKTLASLFSTYASAEADSSAKKGAKKKGSSFQTVSALFRENLNKLMTNL 665
            +TVVGLYQKS++K L++LF+ YA A+A     KG  KKGSSFQTVSAL RENLNKLMTNL
Sbjct: 603  ETVVGLYQKSSLKLLSTLFANYAGADAPIEKGKGKAKKGSSFQTVSALHRENLNKLMTNL 662

Query: 666  RSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYGDFKQRY 725
            RSTHPHFVRCIIPNETK+PG M++ LV+HQLRCNGVLEGIRICRKGFP+RILYGDF+QRY
Sbjct: 663  RSTHPHFVRCIIPNETKSPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRY 722

Query: 726  KVLNASAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDEKLA 785
            ++LN +AIPEGQFIDS+K +EKLL+S+DIDH QYKFGHTKVFFKAGLLGLLEEMRDE+L+
Sbjct: 723  RILNPAAIPEGQFIDSRKGAEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLS 782

Query: 786  QIITRTQAVCRGFLMRVEYQKMLQRREALFCIQYNVRAFMNVKHWPWMKLFFKIKPLLKS 845
            +IITR QA  RG L R+EY+K+L+RR++L  IQ+N+RAFM VK+WPWMKL+FKIKPLLKS
Sbjct: 783  RIITRIQAQSRGVLARMEYKKLLERRDSLLVIQWNIRAFMGVKNWPWMKLYFKIKPLLKS 842

Query: 846  AETEKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLADAE 905
            AE EKEMA+MKEEF + K+ L KSEA+RKELEEKMV+LL+EKNDLQLQVQ+E D+LADAE
Sbjct: 843  AEREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAE 902

Query: 906  ERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLELTLA 965
            ERC+QLIKNKIQLEAK+KE+ ER E+EEE+NAELTAKKRKLEDECSELK+DIDDLELTLA
Sbjct: 903  ERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLA 962

Query: 966  KVEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDKVNILTK 1025
            KVEKEKHATENKVKNLTEEMAGLDE IAKL+KEKKALQE HQQ LDDLQAEEDKVN LTK
Sbjct: 963  KVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTK 1022

Query: 1026 AKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQLDEKLEK 1085
            AK KLEQQVDDLEGSLEQEKK+RMDLERAKRKLEGDLKL QES MD+ENDKQQLDE+L+K
Sbjct: 1023 AKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKK 1082

Query: 1086 KEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQRSDLSRE 1145
            K+FE++ L ++IEDEQA+  QLQKK+KELQARIEEL EE+EAER +RAK EK RSDLSRE
Sbjct: 1083 KDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRE 1142

Query: 1146 LEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRKKHADSMAE 1205
            LEEISERLEEAGGATS Q+E+NKKREAEFQK+RRDLEEATLQHEA  AALRKKHADS+AE
Sbjct: 1143 LEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAE 1202

Query: 1206 LGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGNLEKMCRSLEDQVSELKTK 1265
            LGEQIDNLQRVKQKLEKEKSE K+E DD++SN E I KAK NLEKMCR+LEDQ++E ++K
Sbjct: 1203 LGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSK 1262

Query: 1266 EEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKHQLEEE 1325
             EE QR +NDLT+QRA+LQTE GE SRQLDEK+AL+SQL+R K   TQQ+E+LK QLEEE
Sbjct: 1263 AEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEE 1322

Query: 1326 TKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQR 1385
             KAKNALAHALQS+RHDCDLLREQYEEE E KAELQR LSKANSEVAQWRTKYETDAIQR
Sbjct: 1323 VKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQR 1382

Query: 1386 TEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAAL 1445
            TEELEEAKKKLAQRLQEAEE VEAVNAKC+SLEKTK RLQNE+EDLM+DVERSNAA AAL
Sbjct: 1383 TEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAAL 1442

Query: 1446 DKKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELFKVKNVYEESLDQLETLRREN 1505
            DKKQRNFDK+L+EWKQKYEE+Q+ELE+SQKE+RSLSTELFK+KN YEESL+ LET +REN
Sbjct: 1443 DKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKREN 1502

Query: 1506 KNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQ 1565
            KNLQ+EISDLTEQ+   GK IHELEK++KQ+E EK E+Q+ALEEAEASLEHEEGKILR Q
Sbjct: 1503 KNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQ 1562

Query: 1566 LELNQVKSEVDRKIAEKDEEIDQLKRNHTRVVETMQSTLDAEIRSRNDALRVKKKMEGDL 1625
            LE NQ+K+E++RK+AEKDEE++Q KRNH RVV+++Q++LDAE RSRN+ALRVKKKMEGDL
Sbjct: 1563 LEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDL 1622

Query: 1626 NEMEIQLNHANRLAAESLRNYRNTQGILKETQLHLDDALRGQEDLKEQLAIVERRANLLQ 1685
            NEMEIQL+HANR+AAE+ +  ++ Q +LK+TQ+ LDDA+R  +DLKE +AIVERR NLLQ
Sbjct: 1623 NEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQ 1682

Query: 1686 AEIEELWATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEVE 1745
            AE+EEL A +EQTERSRK+AEQEL++ SERVQLLH+QNTSLIN KKK++ D+SQLQ+EVE
Sbjct: 1683 AELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVE 1742

Query: 1746 EVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQ 1805
            E +QE RNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKN+EQT+KDLQHRLDEAEQ
Sbjct: 1743 EAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQ 1802

Query: 1806 LALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNVL 1865
            +ALKGGKKQ+QKLEARVRELE E+E EQKRNAE+VKG+RK ERR+KELTYQTEEDRKN+L
Sbjct: 1803 IALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLL 1862

Query: 1866 RLQDLVDKLQAKVKSYKRQAEEAEEQSNANLSKFRKLQHELEEAEERADIAESQVNKLRV 1925
            RLQDLVDKLQ KVK+YKRQAEEAEEQ+N NLSKFRK+QHEL+EAEERADIAESQVNKLR 
Sbjct: 1863 RLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRA 1922

Query: 1926 KSREVHTK 1933
            KSR++ TK
Sbjct: 1923 KSRDIGTK 1930



 Score =  180 bits (457), Expect = 1e-44
 Identities = 194/872 (22%), Positives = 378/872 (43%), Gaps = 117/872 (13%)

Query: 1085 KKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQRSDLSR 1144
            K  F+I  L+   E E+ +       +KE   R++E  E+ EA R              +
Sbjct: 831  KLYFKIKPLLKSAEREKEMA-----SMKEEFTRLKEALEKSEARR--------------K 871

Query: 1145 ELEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRKKHADSMA 1204
            ELEE    L +       QV+  +   A+ ++    L +  +Q EA V  + ++  D   
Sbjct: 872  ELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEE- 930

Query: 1205 ELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGNLEKMCRSLEDQVSELKT 1264
               E    L   K+KLE E SELK + DDL      + K K   E   ++L ++++ L  
Sbjct: 931  ---EMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGL-- 985

Query: 1265 KEEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKHQLEE 1324
                   +I  LT ++  LQ    +    L  ++  V+ L+++K    QQ+++L+  LE+
Sbjct: 986  -----DEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQ 1040

Query: 1325 ETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQ 1384
            E K +  L  A +    D  L +E   + +  K +L   L K + E+     + E D   
Sbjct: 1041 EKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIE-DEQA 1099

Query: 1385 RTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAA 1444
               +L++  K+L  R++E EE +EA     A +EK +  L  E+E++   +E +  A + 
Sbjct: 1100 LGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSV 1159

Query: 1445 LDKKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELFKVKNVYEESLDQL-ETLRR 1503
              +  +  +    + ++  EE   + EA+    R    +         ++L ++ + L +
Sbjct: 1160 QIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEK 1219

Query: 1504 ENKNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILR 1563
            E    + E+ D+T  + +  K    LEK+ + +E +  E ++  EE + S+     +  +
Sbjct: 1220 EKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAK 1279

Query: 1564 IQLELNQVKSEVDRKIAEKDEEIDQLKRN---HTRVVETMQSTLDAEIRSRNDALRVKKK 1620
            +Q E      E+ R++ EK+  I QL R    +T+ +E ++  L+ E++++N        
Sbjct: 1280 LQTE----NGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKN-------- 1327

Query: 1621 MEGDLNEMEIQLNHANRLAAESLRNYRNTQGILKETQLHLDDALRGQEDLKEQLAIVERR 1680
                               A +L++ R+   +L+E           + + K +L  V  +
Sbjct: 1328 -----------------ALAHALQSARHDCDLLREQY-------EEETEAKAELQRVLSK 1363

Query: 1681 ANLLQAEIEELWAT-----LEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLEN 1735
            AN   A+    + T      E+ E ++K   Q L +A E V+ ++ + +SL  TK +L+N
Sbjct: 1364 ANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQN 1423

Query: 1736 DVSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKD 1795
            ++  L  +VE                            +    +A L++ ++N ++ + +
Sbjct: 1424 EIEDLMVDVE----------------------------RSNAAAAALDKKQRNFDKILAE 1455

Query: 1796 LQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKH-ERRVKELT 1854
             + + +E+ Q  L+  +K+ + L   + +L+   E E   + E  K   K+ +  + +LT
Sbjct: 1456 WKQKYEES-QSELESSQKEARSLSTELFKLKNAYE-ESLEHLETFKRENKNLQEEISDLT 1513

Query: 1855 YQTEEDRKNVLRLQDLVDKLQAKVKSYKRQAEEAEEQSNANLSK-------FRKLQHELE 1907
             Q     K +  L+ +  +L+A+    +   EEAE        K       F +++ E+E
Sbjct: 1514 EQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIE 1573

Query: 1908 E--AEERADIAESQVNKLRVKSREVHTKISAE 1937
               AE+  ++ +++ N LRV    + T + AE
Sbjct: 1574 RKLAEKDEEMEQAKRNHLRVVD-SLQTSLDAE 1604



 Score = 36.2 bits (82), Expect = 0.32
 Identities = 38/169 (22%), Positives = 70/169 (41%), Gaps = 28/169 (16%)

Query: 842  LLKSAETEKEMATMKEEFQKT-------------------KDELAKSEAKRKELEEKMVT 882
            L K  +T   +  MK+  ++T                   K +L K EA+ +ELE ++  
Sbjct: 1769 LKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEA 1828

Query: 883  LLKEKNDLQLQVQSEADSLADAEERCEQLIKNKIQLE-------AKIKEVTERAEEEEEI 935
              K   +    ++     + +   + E+  KN ++L+        K+K    +AEE EE 
Sbjct: 1829 EQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQ 1888

Query: 936  NAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEE 984
                 +K RK++ E  E ++  D  E  + K+  +  + +   K L EE
Sbjct: 1889 ANTNLSKFRKVQHELDEAEERADIAESQVNKLRAK--SRDIGTKGLNEE 1935


>gi|156104908 myosin heavy chain 6 [Homo sapiens]
          Length = 1939

 Score = 3104 bits (8047), Expect = 0.0
 Identities = 1554/1931 (80%), Positives = 1752/1931 (90%), Gaps = 2/1931 (0%)

Query: 5    SDAEMAVFGEAAPYLRKSEKERIEAQNKPFDAKTSVFVAEPKESYVKSTIQSKEGGKVTV 64
            +DA+MA FG AA YLRKSEKER+EAQ +PFD +T  FV + KE +VK+ I S+EGGKV  
Sbjct: 2    TDAQMADFGAAAQYLRKSEKERLEAQTRPFDIRTECFVPDDKEEFVKAKILSREGGKVIA 61

Query: 65   KTEGGATLTVREDQVFPMNPPKYDKIEDMAMMTHLHEPGVLYNLKERYAAWMIYTYSGLF 124
            +TE G T+TV+EDQV   NPPK+DKIEDMAM+T LHEP VL+NLKERYAAWMIYTYSGLF
Sbjct: 62   ETENGKTVTVKEDQVLQQNPPKFDKIEDMAMLTFLHEPAVLFNLKERYAAWMIYTYSGLF 121

Query: 125  CVTVNPYKWLPVYKPEVVAAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESG 184
            CVTVNPYKWLPVY  EVVAAYRGKKR EAPPHIFSISDNAYQ+MLTDRENQSILITGESG
Sbjct: 122  CVTVNPYKWLPVYNAEVVAAYRGKKRSEAPPHIFSISDNAYQYMLTDRENQSILITGESG 181

Query: 185  AGKTVNTKRVIQYFATIAVTGEK-KKDESGKMQGTLEDQIISANPLLEAFGNAKTVRNDN 243
            AGKTVNTKRVIQYFA+IA  G++ KKD +   +GTLEDQII ANP LEAFGNAKTVRNDN
Sbjct: 182  AGKTVNTKRVIQYFASIAAIGDRGKKDNANANKGTLEDQIIQANPALEAFGNAKTVRNDN 241

Query: 244  SSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQITSNKKPDLIEM 303
            SSRFGKFIRIHFG TGKLASADIETYLLEKSRV FQLKAER+YHIFYQI SNKKP+L++M
Sbjct: 242  SSRFGKFIRIHFGATGKLASADIETYLLEKSRVIFQLKAERNYHIFYQILSNKKPELLDM 301

Query: 304  LLITTNPYDYAFVSQGEITVPSIDDQEELMATDSAIDILGFTPEEKVSIYKLTGAVMHYG 363
            LL+T NPYDYAFVSQGE++V SIDD EELMATDSA D+LGFT EEK  +YKLTGA+MHYG
Sbjct: 302  LLVTNNPYDYAFVSQGEVSVASIDDSEELMATDSAFDVLGFTSEEKAGVYKLTGAIMHYG 361

Query: 364  NMKFKQKQREEQAEPDGTEVADKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTVQQV 423
            NMKFKQKQREEQAEPDGTE ADK+AYL  LNSADLLK LC+PRVKVGNEYVTKGQ+VQQV
Sbjct: 362  NMKFKQKQREEQAEPDGTEDADKSAYLMGLNSADLLKGLCHPRVKVGNEYVTKGQSVQQV 421

Query: 424  YNAVGALAKAVYEKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINF 483
            Y ++GALAKAVYEKMF WMVTRIN  L+TKQPRQYFIGVLDIAGFEIFDFNS EQLCINF
Sbjct: 422  YYSIGALAKAVYEKMFNWMVTRINATLETKQPRQYFIGVLDIAGFEIFDFNSFEQLCINF 481

Query: 484  TNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPLGIFSILEEECMF 543
            TNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDL ACI+LIEKP+GI SILEEECMF
Sbjct: 482  TNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLQACIDLIEKPMGIMSILEEECMF 541

Query: 544  PKATDTSFKNKLYDQHLGKSANFQKPKVVKGKAEAHFSLIHYAGTVDYNITGWLDKNKDP 603
            PKATD +FK KLYD HLGKS NFQKP+ +KGK EAHFSLIHYAGTVDYNI GWL+KNKDP
Sbjct: 542  PKATDMTFKAKLYDNHLGKSNNFQKPRNIKGKQEAHFSLIHYAGTVDYNILGWLEKNKDP 601

Query: 604  LNDTVVGLYQKSAMKTLASLFSTYASAEA-DSSAKKGAKKKGSSFQTVSALFRENLNKLM 662
            LN+TVV LYQKS++K +A+LFS+YA+A+  DS   KG KKKGSSFQTVSAL RENLNKLM
Sbjct: 602  LNETVVALYQKSSLKLMATLFSSYATADTGDSGKSKGGKKKGSSFQTVSALHRENLNKLM 661

Query: 663  TNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYGDFK 722
            TNLR+THPHFVRCIIPNE K PG M++ LV+HQLRCNGVLEGIRICRKGFP+RILYGDF+
Sbjct: 662  TNLRTTHPHFVRCIIPNERKAPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFR 721

Query: 723  QRYKVLNASAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDE 782
            QRY++LN  AIPEGQFIDS+K +EKLL+S+DIDH QYKFGHTKVFFKAGLLGLLEEMRDE
Sbjct: 722  QRYRILNPVAIPEGQFIDSRKGTEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDE 781

Query: 783  KLAQIITRTQAVCRGFLMRVEYQKMLQRREALFCIQYNVRAFMNVKHWPWMKLFFKIKPL 842
            +L++IITR QA  RG LMR+E++K+++RR+AL  IQ+N+RAFM VK+WPWMKL+FKIKPL
Sbjct: 782  RLSRIITRMQAQARGQLMRIEFKKIVERRDALLVIQWNIRAFMGVKNWPWMKLYFKIKPL 841

Query: 843  LKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLA 902
            LKSAETEKEMATMKEEF + K+ L KSEA+RKELEEKMV+LL+EKNDLQLQVQ+E D+L 
Sbjct: 842  LKSAETEKEMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLN 901

Query: 903  DAEERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLEL 962
            DAEERC+QLIKNKIQLEAK+KE+ ER E+EEE+NAELTAKKRKLEDECSELKKDIDDLEL
Sbjct: 902  DAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLEL 961

Query: 963  TLAKVEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDKVNI 1022
            TLAKVEKEKHATENKVKNLTEEMAGLDE IAKL+KEKKALQE HQQ LDDLQ EEDKVN 
Sbjct: 962  TLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQVEEDKVNS 1021

Query: 1023 LTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQLDEK 1082
            L+K+K KLEQQVDDLEGSLEQEKK+RMDLERAKRKLEGDLKL QES MD+ENDK QL+EK
Sbjct: 1022 LSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEEK 1081

Query: 1083 LEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQRSDL 1142
            L+KKEF+I+   SKIEDEQ + +QLQKK+KE QARIEEL EE+EAER +RAK EK RSDL
Sbjct: 1082 LKKKEFDINQQNSKIEDEQVLALQLQKKLKENQARIEELEEELEAERTARAKVEKLRSDL 1141

Query: 1143 SRELEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRKKHADS 1202
            SRELEEISERLEEAGGATS Q+E+NKKREAEFQK+RRDLEEATLQHEA  AALRKKHADS
Sbjct: 1142 SRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADS 1201

Query: 1203 MAELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGNLEKMCRSLEDQVSEL 1262
            +AELGEQIDNLQRVKQKLEKEKSE K+E DD++SN E I KAK NLEK+ R+LEDQ +E 
Sbjct: 1202 VAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANEY 1261

Query: 1263 KTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKHQL 1322
            + K EE QR +ND T QRA+LQTE GE +RQL+EK+AL+SQL+R K + TQQ+E+LK QL
Sbjct: 1262 RVKLEEAQRSLNDFTTQRAKLQTENGELARQLEEKEALISQLTRGKLSYTQQMEDLKRQL 1321

Query: 1323 EEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDA 1382
            EEE KAKNALAHALQS+RHDCDLLREQYEEE E KAELQR LSKANSEVAQWRTKYETDA
Sbjct: 1322 EEEGKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDA 1381

Query: 1383 IQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAAC 1442
            IQRTEELEEAKKKLAQRLQ+AEE VEAVNAKC+SLEKTK RLQNE+EDLM+DVERSNAA 
Sbjct: 1382 IQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAA 1441

Query: 1443 AALDKKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELFKVKNVYEESLDQLETLR 1502
            AALDKKQRNFDK+L+EWKQKYEE+Q+ELE+SQKE+RSLSTELFK+KN YEESL+ LET +
Sbjct: 1442 AALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFK 1501

Query: 1503 RENKNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKIL 1562
            RENKNLQ+EISDLTEQ+ EGGK +HELEK++KQ+E EK E+Q+ALEEAEASLEHEEGKIL
Sbjct: 1502 RENKNLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQSALEEAEASLEHEEGKIL 1561

Query: 1563 RIQLELNQVKSEVDRKIAEKDEEIDQLKRNHTRVVETMQSTLDAEIRSRNDALRVKKKME 1622
            R QLE NQ+K+E++RK+AEKDEE++Q KRNH RVV+++Q++LDAE RSRN+ LRVKKKME
Sbjct: 1562 RAQLEFNQIKAEIERKLAEKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKME 1621

Query: 1623 GDLNEMEIQLNHANRLAAESLRNYRNTQGILKETQLHLDDALRGQEDLKEQLAIVERRAN 1682
            GDLNEMEIQL+HANR+AAE+ +  ++ Q +LK+TQ+ LDDA+R  +DLKE +AIVERR N
Sbjct: 1622 GDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNN 1681

Query: 1683 LLQAEIEELWATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQLQS 1742
            LLQAE+EEL A +EQTERSRK+AEQEL++ SERVQLLH+QNTSLIN KKK+E+D++QLQS
Sbjct: 1682 LLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMESDLTQLQS 1741

Query: 1743 EVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDE 1802
            EVEE +QE RNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKN+EQT+KDLQHRLDE
Sbjct: 1742 EVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDE 1801

Query: 1803 AEQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHERRVKELTYQTEEDRK 1862
            AEQ+ALKGGKKQ+QKLEARVRELEGE+E EQKRNAE+VKG+RK ERR+KELTYQTEED+K
Sbjct: 1802 AEQIALKGGKKQLQKLEARVRELEGELEAEQKRNAESVKGMRKSERRIKELTYQTEEDKK 1861

Query: 1863 NVLRLQDLVDKLQAKVKSYKRQAEEAEEQSNANLSKFRKLQHELEEAEERADIAESQVNK 1922
            N+LRLQDLVDKLQ KVK+YKRQAEEAEEQ+N NLSKFRK+QHEL+EAEERADIAESQVNK
Sbjct: 1862 NLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNK 1921

Query: 1923 LRVKSREVHTK 1933
            LR KSR++  K
Sbjct: 1922 LRAKSRDIGAK 1932



 Score =  189 bits (479), Expect = 3e-47
 Identities = 196/874 (22%), Positives = 385/874 (44%), Gaps = 121/874 (13%)

Query: 1085 KKEFEISNLISKIEDEQAVEIQLQK--KIKELQARIEELGEEIEAERASRAKAEKQRSDL 1142
            K  F+I  L+   E E+ +    ++  +IKE   + E   +E+E +  S  +   +++DL
Sbjct: 833  KLYFKIKPLLKSAETEKEMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQ---EKNDL 889

Query: 1143 SRELEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRKKHADS 1202
              +++   + L +A       ++   + EA+ +++   LE+     E M A L  K    
Sbjct: 890  QLQVQAEQDNLNDAEERCDQLIKNKIQLEAKVKEMNERLED----EEEMNAELTAK---- 941

Query: 1203 MAELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGNLEKMCRSLEDQVSEL 1262
                          K+KLE E SELK + DDL      + K K   E   ++L ++++ L
Sbjct: 942  --------------KRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGL 987

Query: 1263 KTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKHQL 1322
                     +I  LT ++  LQ    +    L  ++  V+ LS+SK    QQ+++L+  L
Sbjct: 988  -------DEIIAKLTKEKKALQEAHQQALDDLQVEEDKVNSLSKSKVKLEQQVDDLEGSL 1040

Query: 1323 EEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDA 1382
            E+E K +  L  A +    D  L +E   + +  K +L+  L K   ++ Q  +K E + 
Sbjct: 1041 EQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQ 1100

Query: 1383 IQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAAC 1442
            +   + L++  K+   R++E EE +EA     A +EK +  L  E+E++   +E +  A 
Sbjct: 1101 VLALQ-LQKKLKENQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGAT 1159

Query: 1443 AALDKKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELFKVKNVYEESLDQL-ETL 1501
            +   +  +  +    + ++  EE   + EA+    R    +         ++L ++ + L
Sbjct: 1160 SVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKL 1219

Query: 1502 RRENKNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKI 1561
             +E    + E+ D+T  + +  K    LEK+ + +E +  E +  LEEA+ SL     + 
Sbjct: 1220 EKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQR 1279

Query: 1562 LRIQLELNQVKSEVDRKIAEKDEEIDQLKR---NHTRVVETMQSTLDAEIRSRNDALRVK 1618
             ++Q E      E+ R++ EK+  I QL R   ++T+ +E ++  L+ E +++N      
Sbjct: 1280 AKLQTE----NGELARQLEEKEALISQLTRGKLSYTQQMEDLKRQLEEEGKAKN------ 1329

Query: 1619 KKMEGDLNEMEIQLNHANRLAAESLRNYRNTQGILKETQLHLDDALRGQEDLKEQLAIVE 1678
                                 A +L++ R+   +L+E           + + K +L  V 
Sbjct: 1330 -------------------ALAHALQSARHDCDLLREQY-------EEETEAKAELQRVL 1363

Query: 1679 RRANLLQAEIEELWAT-----LEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKL 1733
             +AN   A+    + T      E+ E ++K   Q L DA E V+ ++ + +SL  TK +L
Sbjct: 1364 SKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRL 1423

Query: 1734 ENDVSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTV 1793
            +N++  L  +VE                            +    +A L++ ++N ++ +
Sbjct: 1424 QNEIEDLMVDVE----------------------------RSNAAAAALDKKQRNFDKIL 1455

Query: 1794 KDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKH-ERRVKE 1852
             + + + +E+ Q  L+  +K+ + L   + +L+   E E   + E  K   K+ +  + +
Sbjct: 1456 AEWKQKYEES-QSELESSQKEARSLSTELFKLKNAYE-ESLEHLETFKRENKNLQEEISD 1513

Query: 1853 LTYQTEEDRKNVLRLQDLVDKLQAKVKSYKRQAEEAEEQSNANLSK-------FRKLQHE 1905
            LT Q  E  KNV  L+ +  +L+ +    +   EEAE        K       F +++ E
Sbjct: 1514 LTEQLGEGGKNVHELEKVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAE 1573

Query: 1906 LEE--AEERADIAESQVNKLRVKSREVHTKISAE 1937
            +E   AE+  ++ +++ N  RV    + T + AE
Sbjct: 1574 IERKLAEKDEEMEQAKRNHQRVVD-SLQTSLDAE 1606



 Score = 36.2 bits (82), Expect = 0.32
 Identities = 38/169 (22%), Positives = 68/169 (40%), Gaps = 26/169 (15%)

Query: 842  LLKSAETEKEMATMKEEFQKT-------------------KDELAKSEAKRKELEEKMVT 882
            L K  +T   +  MK+  ++T                   K +L K EA+ +ELE ++  
Sbjct: 1771 LKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELEGELEA 1830

Query: 883  LLKEKNDLQLQVQSEADSLADAEERCEQLIKNKIQLE-------AKIKEVTERAEEEEEI 935
              K   +    ++     + +   + E+  KN ++L+        K+K    +AEE EE 
Sbjct: 1831 EQKRNAESVKGMRKSERRIKELTYQTEEDKKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQ 1890

Query: 936  NAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEE 984
                 +K RK++ E  E ++  D  E  + K+  +      K K   EE
Sbjct: 1891 ANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSRDIGAKQKMHDEE 1939


>gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta [Homo
            sapiens]
          Length = 1983

 Score = 2588 bits (6708), Expect = 0.0
 Identities = 1304/1937 (67%), Positives = 1614/1937 (83%), Gaps = 9/1937 (0%)

Query: 2    SASSDAEMAVFGEAAPYLRKSEKERIEAQNKPFDAKTSVFVAEPKESYVKSTIQSKE-GG 60
            SA++  +++  GE+A YLR+  +E  +    P+D K  V+V + +++YV++ ++S+  GG
Sbjct: 39   SATAMMDVSELGESARYLRQGYQEMTKVHTIPWDGKKRVWVPDEQDAYVEAEVKSEATGG 98

Query: 61   KVTVKTEGGATLTVREDQVFPMNPPKYDKIEDMAMMTHLHEPGVLYNLKERYAAWMIYTY 120
            +VTV+T+    L VRE ++ PMNPP++D +EDMAMMTHL+E  VL+NL++RYA WMIYTY
Sbjct: 99   RVTVETKDQKVLMVREAELQPMNPPRFDLLEDMAMMTHLNEASVLHNLRQRYARWMIYTY 158

Query: 121  SGLFCVTVNPYKWLPVYKPEVVAAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILIT 180
            SGLFCVT+NPYKWLPVY   VVAAY+GK+R ++PPHI++++DNAY  ML +R+NQS+LIT
Sbjct: 159  SGLFCVTINPYKWLPVYTASVVAAYKGKRRSDSPPHIYAVADNAYNDMLRNRDNQSMLIT 218

Query: 181  GESGAGKTVNTKRVIQYFATIAVTGE----KKKDESGKMQGTLEDQIISANPLLEAFGNA 236
            GESGAGKTVNTKRVIQYFA +A  G+    K +  + K  GTLEDQII ANP +EAFGNA
Sbjct: 219  GESGAGKTVNTKRVIQYFAIVAALGDGPGKKAQFLATKTGGTLEDQIIEANPAMEAFGNA 278

Query: 237  KTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQITSNK 296
            KT+RNDNSSRFGKFIRIHFG +GKLASADI++YLLEKSRV FQL  ERSYH++YQI S +
Sbjct: 279  KTLRNDNSSRFGKFIRIHFGPSGKLASADIDSYLLEKSRVIFQLPGERSYHVYYQILSGR 338

Query: 297  KPDLIEMLLITTNPYDYAFVSQGEITVPSIDDQEELMATDSAIDILGFTPEEKVSIYKLT 356
            KP+L +MLL++ NPYDY F SQG ITV +++D EEL+ATD A+DILGF+ +EK + YK+ 
Sbjct: 339  KPELQDMLLLSMNPYDYHFCSQGVITVDNMNDGEELIATDHAMDILGFSVDEKCACYKIV 398

Query: 357  GAVMHYGNMKFKQKQREEQAEPDGTEVADKAAYLQSLNSADLLKALCYPRVKVGNEYVTK 416
            GA++H+GNMKFKQKQREEQAE DGTE ADKAAYL  ++S DLLK L +PRV+VGNEYVTK
Sbjct: 399  GALLHFGNMKFKQKQREEQAEADGTESADKAAYLMGVSSGDLLKGLLHPRVRVGNEYVTK 458

Query: 417  GQTVQQVYNAVGALAKAVYEKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSL 476
            GQ+V+QV  AVGALAKA Y+++F W+V+RINQ LDTK PRQ+FIGVLDIAGFEIF+FNS 
Sbjct: 459  GQSVEQVVFAVGALAKATYDRLFRWLVSRINQTLDTKLPRQFFIGVLDIAGFEIFEFNSF 518

Query: 477  EQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPLGIFSI 536
            EQLCINFTNEKLQQFFN HMFVLEQEEYK+EGI+W FIDFG+DL  CI+LIEKPLGI SI
Sbjct: 519  EQLCINFTNEKLQQFFNQHMFVLEQEEYKREGIDWVFIDFGLDLQPCIDLIEKPLGILSI 578

Query: 537  LEEECMFPKATDTSFKNKLYDQHLGKSANFQKPKV-VKGKAEAHFSLIHYAGTVDYNITG 595
            LEEECMFPKA+D SF+ KLYD H GKS NFQ+P+   K K +AHF ++HYAG V Y+I G
Sbjct: 579  LEEECMFPKASDASFRAKLYDNHAGKSPNFQQPRPDKKRKYQAHFEVVHYAGVVPYSIVG 638

Query: 596  WLDKNKDPLNDTVVGLYQKSAMKTLASLFSTYA---SAEADSSAKKGAKKKGSSFQTVSA 652
            WL+KNKDPLN+TVV ++QKS  + LA+L+  YA   S E   S  K  +KK +SFQTVS 
Sbjct: 639  WLEKNKDPLNETVVPIFQKSQNRLLATLYENYAGSCSTEPPKSGVKEKRKKAASFQTVSQ 698

Query: 653  LFRENLNKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGF 712
            L +ENLNKLMTNLR+T PHFVRCI+PNE KTPG M+  LVLHQLRCNGVLEGIRICR+GF
Sbjct: 699  LHKENLNKLMTNLRATQPHFVRCIVPNENKTPGVMDAFLVLHQLRCNGVLEGIRICRQGF 758

Query: 713  PSRILYGDFKQRYKVLNASAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGL 772
            P+R+LY DF+QRY++LN SAIP+  F+DS+KA+EKLL S+D+DHTQY+FGHTKVFFKAGL
Sbjct: 759  PNRLLYTDFRQRYRILNPSAIPDDTFMDSRKATEKLLGSLDLDHTQYQFGHTKVFFKAGL 818

Query: 773  LGLLEEMRDEKLAQIITRTQAVCRGFLMRVEYQKMLQRREALFCIQYNVRAFMNVKHWPW 832
            LG+LEE+RD++LA+++T  QA  RG LMR+EYQ++L  R+ALF IQ+N+RAF  VK+W W
Sbjct: 819  LGVLEELRDQRLAKVLTLLQARSRGRLMRLEYQRLLGGRDALFTIQWNIRAFNAVKNWSW 878

Query: 833  MKLFFKIKPLLKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQL 892
            MKLFFK+KPLL+SA+ E+E+A ++ E +  +  LA +EAKR+ELEE  V++ +EKNDL L
Sbjct: 879  MKLFFKMKPLLRSAQAEEELAALRAELRGLRGALAAAEAKRQELEETHVSITQEKNDLAL 938

Query: 893  QVQSEADSLADAEERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSE 952
            Q+Q+E D+LADAEERC  LIK+K+QLE K+KE++ER E+EEE+NA+L A++RKLEDEC+E
Sbjct: 939  QLQAEQDNLADAEERCHLLIKSKVQLEGKVKELSERLEDEEEVNADLAARRRKLEDECTE 998

Query: 953  LKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDD 1012
            LKKDIDDL+LTLAK EKEK ATENKVKNLTEEMA LDE++A+L+KEKKALQE HQQ L D
Sbjct: 999  LKKDIDDLKLTLAKAEKEKQATENKVKNLTEEMAALDESVARLTKEKKALQEAHQQALGD 1058

Query: 1013 LQAEEDKVNILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDM 1072
            LQAEED+V+ LTKAK +LEQQV+DLE SLEQEKKLRMD ERAKRKLEGDLKL QES  D 
Sbjct: 1059 LQAEEDRVSALTKAKLRLEQQVEDLECSLEQEKKLRMDTERAKRKLEGDLKLTQESVADA 1118

Query: 1073 ENDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAERASR 1132
              DKQQL+EKL+KK+ E+S L  ++EDEQ +  Q+QKKIKELQAR EEL EE+EAERA+R
Sbjct: 1119 AQDKQQLEEKLKKKDSELSQLSLRVEDEQLLGAQMQKKIKELQARAEELEEELEAERAAR 1178

Query: 1133 AKAEKQRSDLSRELEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQHEAMV 1192
            A+ EKQR++ +RELEE+SERLEEAGGA++ Q E  +KREAE  +LRR+LEEA L+HEA V
Sbjct: 1179 ARVEKQRAEAARELEELSERLEEAGGASAGQREGCRKREAELGRLRRELEEAALRHEATV 1238

Query: 1193 AALRKKHADSMAELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGNLEKMC 1252
            AALR+K A+  AELGEQ+D+LQRV+QKLEKEKSEL+ME DDL++N E +++AK + EK+C
Sbjct: 1239 AALRRKQAEGAAELGEQVDSLQRVRQKLEKEKSELRMEVDDLAANVETLTRAKASAEKLC 1298

Query: 1253 RSLEDQVSELKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQAST 1312
            R+ EDQ+SE K K EE QR + D + QR RLQTE+GE SR L+EK+ L+SQLSR K  + 
Sbjct: 1299 RTYEDQLSEAKIKVEELQRQLADASTQRGRLQTESGELSRLLEEKECLISQLSRGKALAA 1358

Query: 1313 QQIEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVA 1372
            Q +EEL+ QLEEE+KAK+ALAHA+Q+ RHDCDLLREQ+EEE E +AELQR LSKAN+EVA
Sbjct: 1359 QSLEELRRQLEEESKAKSALAHAVQALRHDCDLLREQHEEEAEAQAELQRLLSKANAEVA 1418

Query: 1373 QWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLM 1432
            QWR+KYE DAIQRTEELEEAKKKLA RLQEAEE VEA NAKC+SLEK K RLQ E ED+ 
Sbjct: 1419 QWRSKYEADAIQRTEELEEAKKKLALRLQEAEEGVEAANAKCSSLEKAKLRLQTESEDVT 1478

Query: 1433 LDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELFKVKNVYE 1492
            L++ER+ +A AALDKKQR+ ++ L E +++ EE Q ELEA+Q+ESR L TELF++++ +E
Sbjct: 1479 LELERATSAAAALDKKQRHLERALEERRRQEEEMQRELEAAQRESRGLGTELFRLRHGHE 1538

Query: 1493 ESLDQLETLRRENKNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEA 1552
            E+L+ LETL+RENKNLQ+EISDLT+Q++  GK I ELEK KK +E EK EIQAALEEAE 
Sbjct: 1539 EALEALETLKRENKNLQEEISDLTDQVSLSGKSIQELEKTKKALEGEKSEIQAALEEAEG 1598

Query: 1553 SLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHTRVVETMQSTLDAEIRSRN 1612
            +LE EE K LRIQLEL+QVK+EVDRK+AEKDEE   L+RNH R VE++Q++LDAE R+RN
Sbjct: 1599 ALELEETKTLRIQLELSQVKAEVDRKLAEKDEECANLRRNHQRAVESLQASLDAETRARN 1658

Query: 1613 DALRVKKKMEGDLNEMEIQLNHANRLAAESLRNYRNTQGILKETQLHLDDALRGQEDLKE 1672
            +ALR+KKKMEGDLN++E+QL HA R A E+    R  Q  LKE Q   D+  R   +L E
Sbjct: 1659 EALRLKKKMEGDLNDLELQLGHATRQATEAQAATRLMQAQLKEEQAGRDEEQRLAAELHE 1718

Query: 1673 QLAIVERRANLLQAEIEELWATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKK 1732
            Q   +ERRA+LL AE+EEL A LEQ ERSR++AEQELL+A+ER+ LLH+QNT L+N KKK
Sbjct: 1719 QAQALERRASLLAAELEELRAALEQGERSRRLAEQELLEATERLNLLHSQNTGLLNQKKK 1778

Query: 1733 LENDVSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQT 1792
            LE D++QL  EVEE  QE R AEEKAKKAITDAAMMAEELKKEQDTSAHLERMKK LEQT
Sbjct: 1779 LEADLAQLSGEVEEAAQERREAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKTLEQT 1838

Query: 1793 VKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHERRVKE 1852
            V++LQ RL+EAEQ AL+GGKKQ+QKLEA+VRELE E++ EQK++AEA+KG+RKHERRVKE
Sbjct: 1839 VRELQARLEEAEQAALRGGKKQVQKLEAKVRELEAELDAEQKKHAEALKGVRKHERRVKE 1898

Query: 1853 LTYQTEEDRKNVLRLQDLVDKLQAKVKSYKRQAEEAEEQSNANLSKFRKLQHELEEAEER 1912
            L YQ EEDRKN+ R+QDLVDKLQ+KVKSYKRQ EEAE+Q+N NL+K+RK QHEL++AEER
Sbjct: 1899 LAYQAEEDRKNLARMQDLVDKLQSKVKSYKRQFEEAEQQANTNLAKYRKAQHELDDAEER 1958

Query: 1913 ADIAESQVNKLRVKSRE 1929
            AD+AE+Q NKLR ++R+
Sbjct: 1959 ADMAETQANKLRARTRD 1975



 Score =  226 bits (576), Expect = 2e-58
 Identities = 206/930 (22%), Positives = 416/930 (44%), Gaps = 70/930 (7%)

Query: 1030 LEQQVDDLEGSLEQEKKLRMDLERA-------KRKLEGDLKLAQESTMDMENDKQQLDEK 1082
            L  ++  L G+L   +  R +LE         K  L   L+  Q++  D E     L + 
Sbjct: 901  LRAELRGLRGALAAAEAKRQELEETHVSITQEKNDLALQLQAEQDNLADAEERCHLLIKS 960

Query: 1083 LEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQRSDL 1142
              + E ++  L  ++EDE+ V   L  + ++L+    EL ++I+  + + AKAEK++   
Sbjct: 961  KVQLEGKVKELSERLEDEEEVNADLAARRRKLEDECTELKKDIDDLKLTLAKAEKEKQAT 1020

Query: 1143 SRELEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRKKHADS 1202
              +++ ++E +     + +   +  K  +   Q+   DL+      E  V+AL K    +
Sbjct: 1021 ENKVKNLTEEMAALDESVARLTKEKKALQEAHQQALGDLQA----EEDRVSALTK----A 1072

Query: 1203 MAELGEQIDNL-----QRVKQKLEKEKSELKMETDDLSSNAEAISKA---KGNLEKMCRS 1254
               L +Q+++L     Q  K +++ E+++ K+E  DL    E+++ A   K  LE+  + 
Sbjct: 1073 KLRLEQQVEDLECSLEQEKKLRMDTERAKRKLE-GDLKLTQESVADAAQDKQQLEEKLKK 1131

Query: 1255 LEDQVSELKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQ 1314
             + ++S+L  + E++Q L   +  +   LQ  A E   +L+ + A  +++ + +  + ++
Sbjct: 1132 KDSELSQLSLRVEDEQLLGAQMQKKIKELQARAEELEEELEAERAARARVEKQRAEAARE 1191

Query: 1315 IEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQW 1374
            +EEL  +LEE   A           R  C                      K  +E+ + 
Sbjct: 1192 LEELSERLEEAGGAS-------AGQREGC---------------------RKREAELGRL 1223

Query: 1375 RTKYETDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLD 1434
            R + E  A++    +   ++K A+   E  E V+++      LEK K  L+ EV+DL  +
Sbjct: 1224 RRELEEAALRHEATVAALRRKQAEGAAELGEQVDSLQRVRQKLEKEKSELRMEVDDLAAN 1283

Query: 1435 VERSNAACAALDKKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELFKVKNVYEES 1494
            VE    A A+ +K  R ++  LSE K K EE Q +L  +  +   L TE  ++  + EE 
Sbjct: 1284 VETLTRAKASAEKLCRTYEDQLSEAKIKVEELQRQLADASTQRGRLQTESGELSRLLEEK 1343

Query: 1495 LDQLETLRRENKNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASL 1554
               +  L R      Q + +L  Q+ E  K    L    + +  + C++     E EA  
Sbjct: 1344 ECLISQLSRGKALAAQSLEELRRQLEEESKAKSALAHAVQALRHD-CDLLREQHEEEAEA 1402

Query: 1555 EHEEGKIL-RIQLELNQVKSEVDRKIAEKDEEIDQLKRNHTRVVETMQSTLDAEIRSRND 1613
            + E  ++L +   E+ Q +S+ +    ++ EE+++ K+     ++  +  ++A     + 
Sbjct: 1403 QAELQRLLSKANAEVAQWRSKYEADAIQRTEELEEAKKKLALRLQEAEEGVEAANAKCSS 1462

Query: 1614 ALRVKKKMEGDLNEMEIQLNHANRLAAESLRNYRNTQGILKETQLHLDDALRGQEDLKEQ 1673
              + K +++ +  ++ ++L  A   AA   +  R+ +  L+E +       R +E+++ +
Sbjct: 1463 LEKAKLRLQTESEDVTLELERATSAAAALDKKQRHLERALEERR-------RQEEEMQRE 1515

Query: 1674 LAIVERRANLLQAEI-------EELWATLEQTERSRKIAEQELLDASERVQLLHTQNTSL 1726
            L   +R +  L  E+       EE    LE  +R  K  ++E+ D +++V L       L
Sbjct: 1516 LEAAQRESRGLGTELFRLRHGHEEALEALETLKRENKNLQEEISDLTDQVSLSGKSIQEL 1575

Query: 1727 INTKKKLENDVSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEEL-KKEQDTSAHLERM 1785
              TKK LE + S++Q+ +EE        E K  +   + + +  E+ +K  +       +
Sbjct: 1576 EKTKKALEGEKSEIQAALEEAEGALELEETKTLRIQLELSQVKAEVDRKLAEKDEECANL 1635

Query: 1786 KKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRK 1845
            ++N ++ V+ LQ  LD AE  A     +  +K+E  + +LE ++ +  ++  EA    R 
Sbjct: 1636 RRNHQRAVESLQASLD-AETRARNEALRLKKKMEGDLNDLELQLGHATRQATEAQAATRL 1694

Query: 1846 HERRVKELTYQTEEDRKNVLRLQDLVDKLQAKVKSYKRQAEEAEEQSNANLSKFRKLQHE 1905
             + ++KE     +E+++    L +    L+ +      + EE            R  + E
Sbjct: 1695 MQAQLKEEQAGRDEEQRLAAELHEQAQALERRASLLAAELEELRAALEQGERSRRLAEQE 1754

Query: 1906 LEEAEERADIAESQVNKLRVKSREVHTKIS 1935
            L EA ER ++  SQ   L  + +++   ++
Sbjct: 1755 LLEATERLNLLHSQNTGLLNQKKKLEADLA 1784


>gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens]
          Length = 1946

 Score = 2310 bits (5985), Expect = 0.0
 Identities = 1150/1931 (59%), Positives = 1529/1931 (79%), Gaps = 7/1931 (0%)

Query: 8    EMAVFGEAAPYLRKSEKERIEAQNKPFDAKTSVFVAEPKESYVKSTIQ-SKEGGKVTVKT 66
            +++  GEAA +LR+SE E +  Q    D K   ++ + + +Y+++ ++ S++ G V V+T
Sbjct: 22   DLSDLGEAAAFLRRSEAELLLLQATALDGKKKCWIPDGENAYIEAEVKGSEDDGTVIVET 81

Query: 67   EGGATLTVREDQVFPMNPPKYDKIEDMAMMTHLHEPGVLYNLKERYAAWMIYTYSGLFCV 126
              G +L+++ED++  MNPP+++ IEDMAM+THL+E  VL+ LK RY  WMIYTYSGLFCV
Sbjct: 82   ADGESLSIKEDKIQQMNPPEFEMIEDMAMLTHLNEASVLHTLKRRYGQWMIYTYSGLFCV 141

Query: 127  TVNPYKWLPVYKPEVVAAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAG 186
            T+NPYKWLPVY+ EV+AAY+GK+R EAPPHIF++++NA+Q ML +RENQSIL TGESGAG
Sbjct: 142  TINPYKWLPVYQKEVMAAYKGKRRSEAPPHIFAVANNAFQDMLHNRENQSILFTGESGAG 201

Query: 187  KTVNTKRVIQYFATIAVTGEKKKDESGKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSR 246
            KTVN+K +IQYFATIA        ES K QG LEDQI+ AN +LEAFGNAKT+RNDNSSR
Sbjct: 202  KTVNSKHIIQYFATIAAM-----IESRKKQGALEDQIMQANTILEAFGNAKTLRNDNSSR 256

Query: 247  FGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQITSNKKPDLIEMLLI 306
            FGKFIR+HFG  G L+S DI+ YLLEKSRV FQ   ER+YHIFYQI S +K +L ++LL+
Sbjct: 257  FGKFIRMHFGARGMLSSVDIDIYLLEKSRVIFQQAGERNYHIFYQILSGQK-ELHDLLLV 315

Query: 307  TTNPYDYAFVSQGEITVPSIDDQEELMATDSAIDILGFTPEEKVSIYKLTGAVMHYGNMK 366
            + NP D+ F S G +TV S+DD EEL+AT+ A+DILGF P+EK   YKLTGA+MH+GNMK
Sbjct: 316  SANPSDFHFCSCGAVTVESLDDAEELLATEQAMDILGFLPDEKYGCYKLTGAIMHFGNMK 375

Query: 367  FKQKQREEQAEPDGTEVADKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTVQQVYNA 426
            FKQK REEQ E DGTE ADKAA+L  +NS++L+K L +PR+KVGNEYVT+GQT++QV  A
Sbjct: 376  FKQKPREEQLEADGTENADKAAFLMGINSSELVKCLIHPRIKVGNEYVTRGQTIEQVTCA 435

Query: 427  VGALAKAVYEKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNE 486
            VGAL+K++YE+MF W+V RIN+ LD K  RQ+FIG+LDI GFEI ++NSLEQLCINFTNE
Sbjct: 436  VGALSKSMYERMFKWLVARINRALDAKLSRQFFIGILDITGFEILEYNSLEQLCINFTNE 495

Query: 487  KLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPLGIFSILEEECMFPKA 546
            KLQQFFN HMFVLEQEEYKKE IEW  I FG+DL ACI+LIEKP+GI SILEEECMFPKA
Sbjct: 496  KLQQFFNWHMFVLEQEEYKKESIEWVSIGFGLDLQACIDLIEKPMGILSILEEECMFPKA 555

Query: 547  TDTSFKNKLYDQHLGKSANFQKPKVVKGKAEAHFSLIHYAGTVDYNITGWLDKNKDPLND 606
            TD +FK KL+D H GKS + QKPK  K K EAHF L+HYAG V YNI+GWL+KNKD LN+
Sbjct: 556  TDLTFKTKLFDNHFGKSVHLQKPKPDKKKFEAHFELVHYAGVVPYNISGWLEKNKDLLNE 615

Query: 607  TVVGLYQKSAMKTLASLFSTYASAEADSSAKKGAKKKGSSFQTVSALFRENLNKLMTNLR 666
            TVV ++QKS+ + LASLF  Y S ++     +  +KKG+SFQTV++L +ENLNKLMTNL+
Sbjct: 616  TVVAVFQKSSNRLLASLFENYMSTDSAIPFGEKKRKKGASFQTVASLHKENLNKLMTNLK 675

Query: 667  STHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYGDFKQRYK 726
            ST PHFVRCI PN  K PG ++  LVL QLRCNGVLEG RICR+GFP+R+ Y DFKQRY 
Sbjct: 676  STAPHFVRCINPNVNKIPGILDPYLVLQQLRCNGVLEGTRICREGFPNRLQYADFKQRYC 735

Query: 727  VLNASAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDEKLAQ 786
            +LN    P+ +F+ S+KA+E+LL S++IDHTQY+FG TKVFFKAG LG LE +RDE+L++
Sbjct: 736  ILNPRTFPKSKFVSSRKAAEELLGSLEIDHTQYRFGITKVFFKAGFLGQLEAIRDERLSK 795

Query: 787  IITRTQAVCRGFLMRVEYQKMLQRREALFCIQYNVRAFMNVKHWPWMKLFFKIKPLLKSA 846
            + T  QA  +G LMR+++QK+L+ R+AL  IQ+N+RAFM VK+WPWM+LFFKIKPL+KS+
Sbjct: 796  VFTLFQARAQGKLMRIKFQKILEERDALILIQWNIRAFMAVKNWPWMRLFFKIKPLVKSS 855

Query: 847  ETEKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLADAEE 906
            E  +E+A +KEE  + +  L KSE +R+EL+ K V+L +EKNDL LQ+Q+E ++LA+ EE
Sbjct: 856  EVGEEVAGLKEECAQLQKALEKSEFQREELKAKQVSLTQEKNDLILQLQAEQETLANVEE 915

Query: 907  RCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLELTLAK 966
            +CE LIK+KIQLEA++KE++ER EEEEEIN+ELTA+ RKLEDEC ELKK+IDDLE  L K
Sbjct: 916  QCEWLIKSKIQLEARVKELSERVEEEEEINSELTARGRKLEDECFELKKEIDDLETMLVK 975

Query: 967  VEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDKVNILTKA 1026
             EKEK  TE+KVKNLTEE+  L+E I+KL++  K +QE HQQTLDDL  EE+K++ L+KA
Sbjct: 976  SEKEKRTTEHKVKNLTEEVEFLNEDISKLNRAAKVVQEAHQQTLDDLHMEEEKLSSLSKA 1035

Query: 1027 KTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQLDEKLEKK 1086
              KLEQQVD+LEG+LEQE+K RM+ ER   KLEG+LKL +ES  ++E+ ++ L E+L KK
Sbjct: 1036 NLKLEQQVDELEGALEQERKARMNCERELHKLEGNLKLNRESMENLESSQRHLAEELRKK 1095

Query: 1087 EFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQRSDLSREL 1146
            E E+S + SK+E+E+ +  QLQK +KELQ +I++L E++EAER +RAK E++R+DL+++L
Sbjct: 1096 ELELSQMNSKVENEKGLVAQLQKTVKELQTQIKDLKEKLEAERTTRAKMERERADLTQDL 1155

Query: 1147 EEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRKKHADSMAEL 1206
             +++ERLEE GG++ AQ+E+ KK+E +FQKL RD+EEATL  E   A+L+K+HADS+AEL
Sbjct: 1156 ADLNERLEEVGGSSLAQLEITKKQETKFQKLHRDMEEATLHFETTSASLKKRHADSLAEL 1215

Query: 1207 GEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGNLEKMCRSLEDQVSELKTKE 1266
              Q++NLQ+VKQKLEK+KS+L++E DDL +  E +++AK N EK+C   E+++ E   K 
Sbjct: 1216 EGQVENLQQVKQKLEKDKSDLQLEVDDLLTRVEQMTRAKANAEKLCTLYEERLHEATAKL 1275

Query: 1267 EEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKHQLEEET 1326
            ++  +L NDL AQ+ +L +E+GE+ R+L+EK+AL++QLSR K   T+QIE+L+ QLE+ET
Sbjct: 1276 DKVTQLANDLAAQKTKLWSESGEFLRRLEEKEALINQLSREKSNFTRQIEDLRGQLEKET 1335

Query: 1327 KAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRT 1386
            K+++ALAHALQ ++ DCDLLREQYEEEQE KAEL R LSK N+E+ QWR KYE + IQRT
Sbjct: 1336 KSQSALAHALQKAQRDCDLLREQYEEEQEVKAELHRTLSKVNAEMVQWRMKYENNVIQRT 1395

Query: 1387 EELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALD 1446
            E+LE+AKK+LA RLQEA E +   NA+ ASLE+ + +LQ E+ D + D+ +  +A A LD
Sbjct: 1396 EDLEDAKKELAIRLQEAAEAMGVANARNASLERARHQLQLELGDALSDLGKVRSAAARLD 1455

Query: 1447 KKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELFKVKNVYEESLDQLETLRRENK 1506
            +KQ    K L++WKQK+EE+QA L+ASQKE ++LSTEL K+KN YEES+   ETLRRENK
Sbjct: 1456 QKQLQSGKALADWKQKHEESQALLDASQKEVQALSTELLKLKNTYEESIVGQETLRRENK 1515

Query: 1507 NLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQL 1566
            NLQ+EIS+LT Q+ EG K + E+EK+KK +E+EK E+Q  LEE E +LE  E KIL  QL
Sbjct: 1516 NLQEEISNLTNQVREGTKNLTEMEKVKKLIEEEKTEVQVTLEETEGALERNESKILHFQL 1575

Query: 1567 ELNQVKSEVDRKIAEKDEEIDQLKRNHTRVVETMQSTLDAEIRSRNDALRVKKKMEGDLN 1626
            EL + K+E++RK++EKDEEI+  +R     ++++QS+LD+E +SR +  R+KKKME DLN
Sbjct: 1576 ELLEAKAELERKLSEKDEEIENFRRKQQCTIDSLQSSLDSEAKSRIEVTRLKKKMEEDLN 1635

Query: 1627 EMEIQLNHANRLAAESLRNYRNTQGILKETQLHLDDALRGQEDLKEQLAIVERRANLLQA 1686
            EME+QL+ ANR  +E+ ++    Q  +K+ Q+ LDD+ +   DLKEQ+A+ ERR +LLQ+
Sbjct: 1636 EMELQLSCANRQVSEATKSLGQLQIQIKDLQMQLDDSTQLNSDLKEQVAVAERRNSLLQS 1695

Query: 1687 EIEELWATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEE 1746
            E+E+L +  EQTER R+++E+ELL+A+ER+ L +TQNTSL++ KKKLE DV+++Q E EE
Sbjct: 1696 ELEDLRSLQEQTERGRRLSEEELLEATERINLFYTQNTSLLSQKKKLEADVARMQKEAEE 1755

Query: 1747 VIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQL 1806
            V+QE +NAEEKAKKA  +AA ++EELKK+QDT AHLER ++N+EQT+ DLQ RL EAEQ+
Sbjct: 1756 VVQECQNAEEKAKKAAIEAANLSEELKKKQDTIAHLERTRENMEQTITDLQKRLAEAEQM 1815

Query: 1807 ALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNVLR 1866
            AL G +KQIQKLE+RVRELEGE+E E +R+AEA +G R+ ER +KELTYQ EED+KN+ R
Sbjct: 1816 ALMGSRKQIQKLESRVRELEGELEGEIRRSAEAQRGARRLERCIKELTYQAEEDKKNLSR 1875

Query: 1867 LQDLVDKLQAKVKSYKRQAEEAEEQSNANLSKFRKLQHELEEAEERADIAESQVNKLRVK 1926
            +Q  +DKLQ KV++YK+Q E AE Q+N  LSK++K QHEL E +ERA++AESQVNKL++K
Sbjct: 1876 MQTQMDKLQLKVQNYKQQVEVAETQANQYLSKYKKQQHELNEVKERAEVAESQVNKLKIK 1935

Query: 1927 SREVHTKISAE 1937
            +RE   K+  E
Sbjct: 1936 AREFGKKVQEE 1946


>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
            sapiens]
          Length = 1972

 Score = 1435 bits (3714), Expect = 0.0
 Identities = 789/1911 (41%), Positives = 1189/1911 (62%), Gaps = 31/1911 (1%)

Query: 36   AKTSVFVAEPKESYVKSTIQSKEGGKVTVK-TEGGATLTVREDQVFPMNPPKYDKIEDMA 94
            AK  V+V   K+ +  ++I+ ++G +V V+  E G  +TV +D +  MNPPK+ K+EDMA
Sbjct: 32   AKRLVWVPSEKQGFEAASIKEEKGDEVVVELVENGKKVTVGKDDIQKMNPPKFSKVEDMA 91

Query: 95   MMTHLHEPGVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYKPEVVAAYRGKKRQEAP 154
             +T L+E  VL+NL+ERY + +IYTYSGLFCV VNPYK LP+Y  ++V  Y+GKKR E P
Sbjct: 92   ELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKRHEMP 151

Query: 155  PHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKDESGK 214
            PHI++I+D AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY A +A + + KKD S  
Sbjct: 152  PHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKDTS-- 209

Query: 215  MQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLEKS 274
            + G LE Q++ ANP+LEAFGNAKTV+NDNSSRFGKFIRI+F  TG +  A+IETYLLEKS
Sbjct: 210  ITGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKS 269

Query: 275  RVTFQLKAERSYHIFYQITSNKKPDLIEMLLITTNPYDYAFVSQGEITVPSIDDQEELMA 334
            R   Q + ER++HIFY + +  K  +   LL+     +Y F+S G + +P+  D E    
Sbjct: 270  RAIRQARDERTFHIFYYMIAGAKEKMRSDLLLE-GFNNYTFLSNGFVPIPAAQDDEMFQE 328

Query: 335  TDSAIDILGFTPEEKVSIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKAAYLQSLN 394
            T  A+ I+GF+ EE++SI K+  +V+  GN+ FK+++  +QA       A K  +L  +N
Sbjct: 329  TVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKVCHLMGIN 388

Query: 395  SADLLKALCYPRVKVGNEYVTKGQTVQQVYNAVGALAKAVYEKMFLWMVTRINQQLD-TK 453
              D  +++  PR+KVG + V K QT +Q   AV ALAKA YE++F W++TR+N+ LD T 
Sbjct: 389  VTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRVNKALDKTH 448

Query: 454  QPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTF 513
            +    F+G+LDIAGFEIF+ NS EQLCIN+TNEKLQQ FNH MF+LEQEEY++EGIEW F
Sbjct: 449  RQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNF 508

Query: 514  IDFGMDLAACIELIEKPL---GIFSILEEECMFPKATDTSFKNKLYDQHLGKSANFQKPK 570
            IDFG+DL  CIELIE+P    G+ ++L+EEC FPKATD SF  KL  +  G    FQKPK
Sbjct: 509  IDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQ-GSHPKFQKPK 567

Query: 571  VVKGKAEAHFSLIHYAGTVDYNITGWLDKNKDPLNDTVVGLYQKSAMKTLASLFSTY--- 627
             +K K E  FS+IHYAG VDYN + WL KN DPLND V  L   S+ K +A L+      
Sbjct: 568  QLKDKTE--FSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLWKDVDRI 625

Query: 628  -----ASAEADSSAKKGAKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPNETK 682
                  +   +SS    +K K   F+TV  L++E L KLMT LR+T P+FVRCIIPN  K
Sbjct: 626  VGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCIIPNHEK 685

Query: 683  TPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYGDFKQRYKVLNASAIPEGQFIDSK 742
              G ++  LVL QLRCNGVLEGIRICR+GFP+RI++ +F+QRY++L A+AIP+G F+D K
Sbjct: 686  RSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKG-FMDGK 744

Query: 743  KASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDEKLAQIITRTQAVCRGFLMRV 802
            +A   ++ ++++D   Y+ G +K+FF+ G+L  LEE RD K+  +I   QA+CRG+L R 
Sbjct: 745  QACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRGYLARK 804

Query: 803  EYQKMLQRREALFCIQYNVRAFMNVKHWPWMKLFFKIKPLLKSAETEKEMATMKEEFQKT 862
             + K  Q+  A+  IQ N  A++ +++W W +LF K+KPLL+    E+EM   ++E QKT
Sbjct: 805  AFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKEDELQKT 864

Query: 863  KDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLADAEERCEQLIKNKIQLEAKI 922
            K+   K+E + KELE+K   L +EKN LQ Q+Q+E +  A+AEE   +L   K +LE  +
Sbjct: 865  KERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEIL 924

Query: 923  KEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLT 982
             E+  R EEEE+   +L A+++K+  +  +L++ +++ E    K++ EK   E K+K L 
Sbjct: 925  HEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLE 984

Query: 983  EEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDKVNILTKAKTKLEQQVDDLEGSLE 1042
            +E+  +D+   KLSKE+K L+E       +L  EE+K   LTK K K E  + +LE  L+
Sbjct: 985  DEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLK 1044

Query: 1043 QEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQLDEKLEKKEFEISNLISKIEDEQA 1102
            +E+K R +LE+ KRKLEGD     E   D++    +L  +L KKE E+   +++++DE A
Sbjct: 1045 KEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIA 1104

Query: 1103 VEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSA 1162
             +    KKI+EL+  I +L E++++ERA+R KAEKQ+ DL  ELE +   LE+   +T+ 
Sbjct: 1105 QKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTAT 1164

Query: 1163 QVELNKKREAEFQKLRRDLEEATLQHEAMVAALRKKHADSMAELGEQIDNLQRVKQKLEK 1222
            Q EL  KRE E   L++ L+E T  HEA V  +R+KHA ++ EL EQ++  +R K  L+K
Sbjct: 1165 QQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDK 1224

Query: 1223 EKSELKMETDDLSSNAEAISKAKGNLEKMCRSLEDQVSELKTKEEEQQRLINDLTAQRAR 1282
             K  L+ E  DL+     + +AK  +E   + LE QV EL++K  + +R   +L  +  +
Sbjct: 1225 NKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHK 1284

Query: 1283 LQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKHQLEEETKAKNALAHALQSSRHD 1342
            LQ E    +  L+E +    +L++   + + Q+++ +  L+EET+ K  ++  L+    +
Sbjct: 1285 LQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEE 1344

Query: 1343 CDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQE 1402
             + L++Q +EE E K  L+R +S  N +++  + K + D     E LEE KK+  + ++ 
Sbjct: 1345 RNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQ-DFASTVEALEEGKKRFQKEIEN 1403

Query: 1403 AEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWK-- 1460
              +  E   A    LEKTK RLQ E++DL++D++      + L+KKQR FD++L+E K  
Sbjct: 1404 LTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNI 1463

Query: 1461 -QKY--EETQAELEASQKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEISDLTE 1517
              KY  E  +AE EA +KE+++LS     +    EE+L+  E L R NK L+ E+ DL  
Sbjct: 1464 SSKYADERDRAEAEAREKETKALS-----LARALEEALEAKEELERTNKMLKAEMEDLVS 1518

Query: 1518 QIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEVDR 1577
               + GK +HELEK K+ +E +  E++  LEE E  L+  E   LR+++ +  +K + +R
Sbjct: 1519 SKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFER 1578

Query: 1578 KIAEKDEEIDQLKRNHTRVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEMEIQLNHANR 1637
             +  +DE+ ++ +R   R +   ++ L+ E + R  A   KKK+EGDL ++E+Q + A +
Sbjct: 1579 DLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIK 1638

Query: 1638 LAAESLRNYRNTQGILKETQLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELWATLEQ 1697
               E+++  R  Q  +K+ Q  L+DA   ++++       E++A  L+A++ +L   L  
Sbjct: 1639 GREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAA 1698

Query: 1698 TERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQESRNAEEK 1757
             ER+RK A+ E  + +E +    +   +L + K++LE  ++QL+ E+EE         ++
Sbjct: 1699 AERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDR 1758

Query: 1758 AKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQK 1817
             +KA   A  ++ EL  E+ T+   E  ++ LE+  K+L+ +L E E       K  I  
Sbjct: 1759 VRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAA 1818

Query: 1818 LEARVRELEGEVENEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQAK 1877
            LEA++ +LE +VE E +    A K L++ ++++KE+  Q E++RK   + ++  +K  A+
Sbjct: 1819 LEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNAR 1878

Query: 1878 VKSYKRQAEEAEEQSNANLSKFRKLQHELEEAEERADIAESQVNKLRVKSR 1928
            VK  KRQ EEAEE+S    +  RKLQ EL+EA E  +    +VN L+ K R
Sbjct: 1879 VKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLR 1929



 Score =  225 bits (574), Expect = 3e-58
 Identities = 201/949 (21%), Positives = 438/949 (46%), Gaps = 57/949 (6%)

Query: 996  SKEKKALQETHQQTLDDLQAEEDKVNILTKAKTKLEQQVDDLE---GSLEQEKKLRMDLE 1052
            +K K  LQ T Q+  +++QA+ED++    + + K E ++ +LE     L +EK L  +  
Sbjct: 839  TKVKPLLQVTRQE--EEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQL 896

Query: 1053 RAKRKLEGDLKLAQESTMDMENDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIK 1112
            +A+ +L  +   A+E  + +   KQ+L+E L + E       +++E+E+    QLQ + K
Sbjct: 897  QAETELYAE---AEEMRVRLAAKKQELEEILHEME-------ARLEEEEDRGQQLQAERK 946

Query: 1113 ELQARIEELGEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQVELNKKREA 1172
            ++  ++ +L E++E E A+R K + ++     +++++ + +           + N K   
Sbjct: 947  KMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEI-------LVMDDQNNKLSK 999

Query: 1173 EFQKLRRDLEEATLQHEAMVAALRKKHADSMAELGEQIDNLQRVKQKLEKEKSELKMETD 1232
            E + L   + + T                ++AE  E+  NL ++K K E   SEL++   
Sbjct: 1000 ERKLLEERISDLTT---------------NLAEEEEKAKNLTKLKNKHESMISELEVRL- 1043

Query: 1233 DLSSNAEAISKAKGNLEKMCRSLEDQVSELKTKEEEQQRLINDLTAQRARLQTEAGEYSR 1292
                  +   K++  LEK+ R LE   S+   +  + Q  I +L  Q A+ + E      
Sbjct: 1044 ------KKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALA 1097

Query: 1293 QLDEKDALVSQLSRSKQASTQQIEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEE 1352
            +LD++ A  +   +  +     I +L+  L+ E  A+N      +    + + L+ + E+
Sbjct: 1098 RLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELED 1157

Query: 1353 EQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNA 1412
              +  A  Q   +K   EV   +   + +      +++E ++K AQ ++E  E +E    
Sbjct: 1158 TLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKR 1217

Query: 1413 KCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQAELEA 1472
              A+L+K KQ L+ E  DL  ++     A   ++ K++  +  + E + K  + +     
Sbjct: 1218 AKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAE 1277

Query: 1473 SQKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEISDLTEQIAEGGKQIHELEKI 1532
               +   L  E+  V  +  E+  +   L ++  +L  ++ D  E + E  +Q   +   
Sbjct: 1278 LNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTK 1337

Query: 1533 KKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRN 1592
             +Q+E+E+  +Q  L+E   + ++ E  I  + ++L+  K ++ +  A   E +++ K+ 
Sbjct: 1338 LRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKL-QDFASTVEALEEGKKR 1396

Query: 1593 HTRVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEMEIQLNHANRLAAESLRNYRNTQGI 1652
              + +E +    + +  + +   + K +++ +L+++ + L++  +L +   +  R    +
Sbjct: 1397 FQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQL 1456

Query: 1653 LKE----TQLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELWATLEQTERSRKIAEQE 1708
            L E    +  + D+  R + + +E+    E +A  L   +EE     E+ ER+ K+ + E
Sbjct: 1457 LAEEKNISSKYADERDRAEAEAREK----ETKALSLARALEEALEAKEELERTNKMLKAE 1512

Query: 1709 LLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQESRNAEE-KAKKAITDAAM 1767
            + D       +      L  +K+ LE  + ++++++EE+  E +  E+ K +  +   A+
Sbjct: 1513 MEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQAL 1572

Query: 1768 MAEELKKEQDTSAHLERMKKNLEQTVKDLQHRL-DEAEQLALKGGKKQIQKLEARVRELE 1826
              +  +  Q      E  ++ L++ + + +  L DE +Q AL    K+  KLE  +++LE
Sbjct: 1573 KGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKK--KLEGDLKDLE 1630

Query: 1827 GEVENEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQAKVKSYKRQAE 1886
             + ++  K   EA+K LRK + ++K+   + E+ R +   +     + + K KS +    
Sbjct: 1631 LQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLM 1690

Query: 1887 EAEEQSNANLSKFRKLQHELEEAEERADIAESQVNKLRVKSREVHTKIS 1935
            + +E   A     ++   E EE  E    + S  N L+ + R +  +I+
Sbjct: 1691 QLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIA 1739



 Score =  140 bits (352), Expect = 2e-32
 Identities = 121/529 (22%), Positives = 242/529 (45%), Gaps = 19/529 (3%)

Query: 844  KSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLAD 903
            K+A  +K   T K   Q+  D+L      +++L   +    ++ + L  + ++ +   AD
Sbjct: 1411 KAAAYDKLEKT-KNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYAD 1469

Query: 904  AEERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLELT 963
              +R E   + K   E K   +    EE  E   EL    + L+ E  +L    DD+   
Sbjct: 1470 ERDRAEAEAREK---ETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKN 1526

Query: 964  LAKVEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLD-----DLQAEED 1018
            + ++EK K A E +++ +  ++  L++ + + +++ K   E + Q L      DLQA ++
Sbjct: 1527 VHELEKSKRALETQMEEMKTQLEELEDEL-QATEDAKLRLEVNMQALKGQFERDLQARDE 1585

Query: 1019 KVNILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQ 1078
            +     + + +L++Q+ + E  LE E+K R     AK+KLEGDLK  +         +++
Sbjct: 1586 QNE---EKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREE 1642

Query: 1079 LDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQ 1138
              ++L K + ++ +   ++ED +A   ++    KE + + + L  ++   +   A AE+ 
Sbjct: 1643 AIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERA 1702

Query: 1139 RSDLSRELEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRKK 1198
            R     E EE++E L  +    +A  +  ++ EA   +L  +LEE     EAM   +RK 
Sbjct: 1703 RKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKA 1762

Query: 1199 HADSMAELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKA-KGNLEKMCRSLED 1257
                  +L  ++   +   QK E  + +L+ +  +L S    +  A K   +    +LE 
Sbjct: 1763 -TQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEA 1821

Query: 1258 QVSELKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEE 1317
            ++++L+ + E++ R     T    +   +  E   Q++++  +  Q     +    ++++
Sbjct: 1822 KIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQ 1881

Query: 1318 LKHQL---EEETKAKNALAHALQSSRHDCDLLREQYEEEQEG-KAELQR 1362
            LK QL   EEE++  NA    LQ    +     E    E    K++L+R
Sbjct: 1882 LKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLRR 1930



 Score = 76.6 bits (187), Expect = 2e-13
 Identities = 85/358 (23%), Positives = 161/358 (44%), Gaps = 55/358 (15%)

Query: 1591 RNHTRVVETMQSTL-DAEIRSRNDALRVKK----KMEGDLNEME---IQLNHANRLAAES 1642
            R  T+V   +Q T  + E++++ D L+  K    K E +L E+E    QL     L  E 
Sbjct: 836  RLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQ 895

Query: 1643 LRNYRNTQGILKETQLHLDDALRGQEDLKEQLAI----VERRANLLQAEIEELWATLEQT 1698
            L+          ET+L+ +      E+++ +LA     +E   + ++A +EE     +Q 
Sbjct: 896  LQ---------AETELYAE-----AEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQL 941

Query: 1699 ERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQESRNAEEKA 1758
            +  RK   Q++LD  E+++                E + ++ + ++E+V      AE K 
Sbjct: 942  QAERKKMAQQMLDLEEQLE----------------EEEAARQKLQLEKV-----TAEAKI 980

Query: 1759 KKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKL 1818
            KK       + +E+    D +  L + +K LE+ + DL   L E E+ A K   K   K 
Sbjct: 981  KK-------LEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKA-KNLTKLKNKH 1032

Query: 1819 EARVRELEGEVENEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQAKV 1878
            E+ + ELE  ++ E+K   E  K  RK E    +   Q  + +  +  L+  + K + ++
Sbjct: 1033 ESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEEL 1092

Query: 1879 KSYKRQAEEAEEQSNANLSKFRKLQHELEEAEERADIAESQVNKLRVKSREVHTKISA 1936
            ++   + ++   Q N  L K R+L+  + + +E  D   +  NK   + R++  ++ A
Sbjct: 1093 QAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEA 1150



 Score = 48.1 bits (113), Expect = 8e-05
 Identities = 58/223 (26%), Positives = 101/223 (45%), Gaps = 29/223 (13%)

Query: 1729 TKKKLENDVSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKN 1788
            TK K    V++ + E++    E +  +E+ +KA         ELK+ +   + L   K  
Sbjct: 839  TKVKPLLQVTRQEEEMQAKEDELQKTKERQQKA-------ENELKELEQKHSQLTEEKNL 891

Query: 1789 LEQTVKDLQHRLDEAEQLALK-GGKKQ-----IQKLEARVRELEGEVENEQKRNAEAVKG 1842
            L++ ++       EAE++ ++   KKQ     + ++EAR   LE E +  Q+  AE    
Sbjct: 892  LQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEAR---LEEEEDRGQQLQAER--- 945

Query: 1843 LRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQAKVKSYKRQAEEAEEQSNANLSKFRKL 1902
             +K  +++ +L  Q EE+     +LQ      +AK+K  + +    ++Q+N  LSK RKL
Sbjct: 946  -KKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNN-KLSKERKL 1003

Query: 1903 QHE--------LEEAEERADIAESQVNKLRVKSREVHTKISAE 1937
              E        L E EE+A       NK      E+  ++  E
Sbjct: 1004 LEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKE 1046



 Score = 44.3 bits (103), Expect = 0.001
 Identities = 33/174 (18%), Positives = 74/174 (42%), Gaps = 8/174 (4%)

Query: 840  KPLLKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKE-KNDLQLQVQSEA 898
            K   ++ +   E+AT +   QK +    + E + KEL  K+  +    K+  +  + +  
Sbjct: 1761 KATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALE 1820

Query: 899  DSLADAEERCEQLIKNKI-------QLEAKIKEVTERAEEEEEINAELTAKKRKLEDECS 951
              +A  EE+ EQ  + K        Q + K+KE+  + E+E ++  +   +  K      
Sbjct: 1821 AKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVK 1880

Query: 952  ELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQET 1005
            +LK+ +++ E    ++   +   + ++   TE    +   +  L  + +   ET
Sbjct: 1881 QLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLRRGNET 1934


>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
            sapiens]
          Length = 1938

 Score = 1435 bits (3714), Expect = 0.0
 Identities = 789/1911 (41%), Positives = 1189/1911 (62%), Gaps = 31/1911 (1%)

Query: 36   AKTSVFVAEPKESYVKSTIQSKEGGKVTVK-TEGGATLTVREDQVFPMNPPKYDKIEDMA 94
            AK  V+V   K+ +  ++I+ ++G +V V+  E G  +TV +D +  MNPPK+ K+EDMA
Sbjct: 32   AKRLVWVPSEKQGFEAASIKEEKGDEVVVELVENGKKVTVGKDDIQKMNPPKFSKVEDMA 91

Query: 95   MMTHLHEPGVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYKPEVVAAYRGKKRQEAP 154
             +T L+E  VL+NL+ERY + +IYTYSGLFCV VNPYK LP+Y  ++V  Y+GKKR E P
Sbjct: 92   ELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKRHEMP 151

Query: 155  PHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKDESGK 214
            PHI++I+D AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY A +A + + KKD S  
Sbjct: 152  PHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKDTS-- 209

Query: 215  MQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLEKS 274
            + G LE Q++ ANP+LEAFGNAKTV+NDNSSRFGKFIRI+F  TG +  A+IETYLLEKS
Sbjct: 210  ITGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKS 269

Query: 275  RVTFQLKAERSYHIFYQITSNKKPDLIEMLLITTNPYDYAFVSQGEITVPSIDDQEELMA 334
            R   Q + ER++HIFY + +  K  +   LL+     +Y F+S G + +P+  D E    
Sbjct: 270  RAIRQARDERTFHIFYYMIAGAKEKMRSDLLLE-GFNNYTFLSNGFVPIPAAQDDEMFQE 328

Query: 335  TDSAIDILGFTPEEKVSIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKAAYLQSLN 394
            T  A+ I+GF+ EE++SI K+  +V+  GN+ FK+++  +QA       A K  +L  +N
Sbjct: 329  TVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKVCHLMGIN 388

Query: 395  SADLLKALCYPRVKVGNEYVTKGQTVQQVYNAVGALAKAVYEKMFLWMVTRINQQLD-TK 453
              D  +++  PR+KVG + V K QT +Q   AV ALAKA YE++F W++TR+N+ LD T 
Sbjct: 389  VTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRVNKALDKTH 448

Query: 454  QPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTF 513
            +    F+G+LDIAGFEIF+ NS EQLCIN+TNEKLQQ FNH MF+LEQEEY++EGIEW F
Sbjct: 449  RQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNF 508

Query: 514  IDFGMDLAACIELIEKPL---GIFSILEEECMFPKATDTSFKNKLYDQHLGKSANFQKPK 570
            IDFG+DL  CIELIE+P    G+ ++L+EEC FPKATD SF  KL  +  G    FQKPK
Sbjct: 509  IDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQ-GSHPKFQKPK 567

Query: 571  VVKGKAEAHFSLIHYAGTVDYNITGWLDKNKDPLNDTVVGLYQKSAMKTLASLFSTY--- 627
             +K K E  FS+IHYAG VDYN + WL KN DPLND V  L   S+ K +A L+      
Sbjct: 568  QLKDKTE--FSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLWKDVDRI 625

Query: 628  -----ASAEADSSAKKGAKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPNETK 682
                  +   +SS    +K K   F+TV  L++E L KLMT LR+T P+FVRCIIPN  K
Sbjct: 626  VGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCIIPNHEK 685

Query: 683  TPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYGDFKQRYKVLNASAIPEGQFIDSK 742
              G ++  LVL QLRCNGVLEGIRICR+GFP+RI++ +F+QRY++L A+AIP+G F+D K
Sbjct: 686  RSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKG-FMDGK 744

Query: 743  KASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDEKLAQIITRTQAVCRGFLMRV 802
            +A   ++ ++++D   Y+ G +K+FF+ G+L  LEE RD K+  +I   QA+CRG+L R 
Sbjct: 745  QACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRGYLARK 804

Query: 803  EYQKMLQRREALFCIQYNVRAFMNVKHWPWMKLFFKIKPLLKSAETEKEMATMKEEFQKT 862
             + K  Q+  A+  IQ N  A++ +++W W +LF K+KPLL+    E+EM   ++E QKT
Sbjct: 805  AFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKEDELQKT 864

Query: 863  KDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLADAEERCEQLIKNKIQLEAKI 922
            K+   K+E + KELE+K   L +EKN LQ Q+Q+E +  A+AEE   +L   K +LE  +
Sbjct: 865  KERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEIL 924

Query: 923  KEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLT 982
             E+  R EEEE+   +L A+++K+  +  +L++ +++ E    K++ EK   E K+K L 
Sbjct: 925  HEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLE 984

Query: 983  EEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDKVNILTKAKTKLEQQVDDLEGSLE 1042
            +E+  +D+   KLSKE+K L+E       +L  EE+K   LTK K K E  + +LE  L+
Sbjct: 985  DEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLK 1044

Query: 1043 QEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQLDEKLEKKEFEISNLISKIEDEQA 1102
            +E+K R +LE+ KRKLEGD     E   D++    +L  +L KKE E+   +++++DE A
Sbjct: 1045 KEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIA 1104

Query: 1103 VEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSA 1162
             +    KKI+EL+  I +L E++++ERA+R KAEKQ+ DL  ELE +   LE+   +T+ 
Sbjct: 1105 QKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTAT 1164

Query: 1163 QVELNKKREAEFQKLRRDLEEATLQHEAMVAALRKKHADSMAELGEQIDNLQRVKQKLEK 1222
            Q EL  KRE E   L++ L+E T  HEA V  +R+KHA ++ EL EQ++  +R K  L+K
Sbjct: 1165 QQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDK 1224

Query: 1223 EKSELKMETDDLSSNAEAISKAKGNLEKMCRSLEDQVSELKTKEEEQQRLINDLTAQRAR 1282
             K  L+ E  DL+     + +AK  +E   + LE QV EL++K  + +R   +L  +  +
Sbjct: 1225 NKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHK 1284

Query: 1283 LQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKHQLEEETKAKNALAHALQSSRHD 1342
            LQ E    +  L+E +    +L++   + + Q+++ +  L+EET+ K  ++  L+    +
Sbjct: 1285 LQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEE 1344

Query: 1343 CDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQE 1402
             + L++Q +EE E K  L+R +S  N +++  + K + D     E LEE KK+  + ++ 
Sbjct: 1345 RNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQ-DFASTVEALEEGKKRFQKEIEN 1403

Query: 1403 AEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWK-- 1460
              +  E   A    LEKTK RLQ E++DL++D++      + L+KKQR FD++L+E K  
Sbjct: 1404 LTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNI 1463

Query: 1461 -QKY--EETQAELEASQKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEISDLTE 1517
              KY  E  +AE EA +KE+++LS     +    EE+L+  E L R NK L+ E+ DL  
Sbjct: 1464 SSKYADERDRAEAEAREKETKALS-----LARALEEALEAKEELERTNKMLKAEMEDLVS 1518

Query: 1518 QIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEVDR 1577
               + GK +HELEK K+ +E +  E++  LEE E  L+  E   LR+++ +  +K + +R
Sbjct: 1519 SKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFER 1578

Query: 1578 KIAEKDEEIDQLKRNHTRVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEMEIQLNHANR 1637
             +  +DE+ ++ +R   R +   ++ L+ E + R  A   KKK+EGDL ++E+Q + A +
Sbjct: 1579 DLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIK 1638

Query: 1638 LAAESLRNYRNTQGILKETQLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELWATLEQ 1697
               E+++  R  Q  +K+ Q  L+DA   ++++       E++A  L+A++ +L   L  
Sbjct: 1639 GREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAA 1698

Query: 1698 TERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQESRNAEEK 1757
             ER+RK A+ E  + +E +    +   +L + K++LE  ++QL+ E+EE         ++
Sbjct: 1699 AERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDR 1758

Query: 1758 AKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQK 1817
             +KA   A  ++ EL  E+ T+   E  ++ LE+  K+L+ +L E E       K  I  
Sbjct: 1759 VRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAA 1818

Query: 1818 LEARVRELEGEVENEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQAK 1877
            LEA++ +LE +VE E +    A K L++ ++++KE+  Q E++RK   + ++  +K  A+
Sbjct: 1819 LEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNAR 1878

Query: 1878 VKSYKRQAEEAEEQSNANLSKFRKLQHELEEAEERADIAESQVNKLRVKSR 1928
            VK  KRQ EEAEE+S    +  RKLQ EL+EA E  +    +VN L+ K R
Sbjct: 1879 VKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLR 1929



 Score =  225 bits (574), Expect = 3e-58
 Identities = 201/949 (21%), Positives = 438/949 (46%), Gaps = 57/949 (6%)

Query: 996  SKEKKALQETHQQTLDDLQAEEDKVNILTKAKTKLEQQVDDLE---GSLEQEKKLRMDLE 1052
            +K K  LQ T Q+  +++QA+ED++    + + K E ++ +LE     L +EK L  +  
Sbjct: 839  TKVKPLLQVTRQE--EEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQL 896

Query: 1053 RAKRKLEGDLKLAQESTMDMENDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIK 1112
            +A+ +L  +   A+E  + +   KQ+L+E L + E       +++E+E+    QLQ + K
Sbjct: 897  QAETELYAE---AEEMRVRLAAKKQELEEILHEME-------ARLEEEEDRGQQLQAERK 946

Query: 1113 ELQARIEELGEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQVELNKKREA 1172
            ++  ++ +L E++E E A+R K + ++     +++++ + +           + N K   
Sbjct: 947  KMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEI-------LVMDDQNNKLSK 999

Query: 1173 EFQKLRRDLEEATLQHEAMVAALRKKHADSMAELGEQIDNLQRVKQKLEKEKSELKMETD 1232
            E + L   + + T                ++AE  E+  NL ++K K E   SEL++   
Sbjct: 1000 ERKLLEERISDLTT---------------NLAEEEEKAKNLTKLKNKHESMISELEVRL- 1043

Query: 1233 DLSSNAEAISKAKGNLEKMCRSLEDQVSELKTKEEEQQRLINDLTAQRARLQTEAGEYSR 1292
                  +   K++  LEK+ R LE   S+   +  + Q  I +L  Q A+ + E      
Sbjct: 1044 ------KKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALA 1097

Query: 1293 QLDEKDALVSQLSRSKQASTQQIEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEE 1352
            +LD++ A  +   +  +     I +L+  L+ E  A+N      +    + + L+ + E+
Sbjct: 1098 RLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELED 1157

Query: 1353 EQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNA 1412
              +  A  Q   +K   EV   +   + +      +++E ++K AQ ++E  E +E    
Sbjct: 1158 TLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKR 1217

Query: 1413 KCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQAELEA 1472
              A+L+K KQ L+ E  DL  ++     A   ++ K++  +  + E + K  + +     
Sbjct: 1218 AKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAE 1277

Query: 1473 SQKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEISDLTEQIAEGGKQIHELEKI 1532
               +   L  E+  V  +  E+  +   L ++  +L  ++ D  E + E  +Q   +   
Sbjct: 1278 LNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTK 1337

Query: 1533 KKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRN 1592
             +Q+E+E+  +Q  L+E   + ++ E  I  + ++L+  K ++ +  A   E +++ K+ 
Sbjct: 1338 LRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKL-QDFASTVEALEEGKKR 1396

Query: 1593 HTRVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEMEIQLNHANRLAAESLRNYRNTQGI 1652
              + +E +    + +  + +   + K +++ +L+++ + L++  +L +   +  R    +
Sbjct: 1397 FQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQL 1456

Query: 1653 LKE----TQLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELWATLEQTERSRKIAEQE 1708
            L E    +  + D+  R + + +E+    E +A  L   +EE     E+ ER+ K+ + E
Sbjct: 1457 LAEEKNISSKYADERDRAEAEAREK----ETKALSLARALEEALEAKEELERTNKMLKAE 1512

Query: 1709 LLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQESRNAEE-KAKKAITDAAM 1767
            + D       +      L  +K+ LE  + ++++++EE+  E +  E+ K +  +   A+
Sbjct: 1513 MEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQAL 1572

Query: 1768 MAEELKKEQDTSAHLERMKKNLEQTVKDLQHRL-DEAEQLALKGGKKQIQKLEARVRELE 1826
              +  +  Q      E  ++ L++ + + +  L DE +Q AL    K+  KLE  +++LE
Sbjct: 1573 KGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKK--KLEGDLKDLE 1630

Query: 1827 GEVENEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQAKVKSYKRQAE 1886
             + ++  K   EA+K LRK + ++K+   + E+ R +   +     + + K KS +    
Sbjct: 1631 LQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLM 1690

Query: 1887 EAEEQSNANLSKFRKLQHELEEAEERADIAESQVNKLRVKSREVHTKIS 1935
            + +E   A     ++   E EE  E    + S  N L+ + R +  +I+
Sbjct: 1691 QLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIA 1739



 Score = 76.6 bits (187), Expect = 2e-13
 Identities = 85/358 (23%), Positives = 161/358 (44%), Gaps = 55/358 (15%)

Query: 1591 RNHTRVVETMQSTL-DAEIRSRNDALRVKK----KMEGDLNEME---IQLNHANRLAAES 1642
            R  T+V   +Q T  + E++++ D L+  K    K E +L E+E    QL     L  E 
Sbjct: 836  RLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQ 895

Query: 1643 LRNYRNTQGILKETQLHLDDALRGQEDLKEQLAI----VERRANLLQAEIEELWATLEQT 1698
            L+          ET+L+ +      E+++ +LA     +E   + ++A +EE     +Q 
Sbjct: 896  LQ---------AETELYAE-----AEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQL 941

Query: 1699 ERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQESRNAEEKA 1758
            +  RK   Q++LD  E+++                E + ++ + ++E+V      AE K 
Sbjct: 942  QAERKKMAQQMLDLEEQLE----------------EEEAARQKLQLEKV-----TAEAKI 980

Query: 1759 KKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKL 1818
            KK       + +E+    D +  L + +K LE+ + DL   L E E+ A K   K   K 
Sbjct: 981  KK-------LEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKA-KNLTKLKNKH 1032

Query: 1819 EARVRELEGEVENEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQAKV 1878
            E+ + ELE  ++ E+K   E  K  RK E    +   Q  + +  +  L+  + K + ++
Sbjct: 1033 ESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEEL 1092

Query: 1879 KSYKRQAEEAEEQSNANLSKFRKLQHELEEAEERADIAESQVNKLRVKSREVHTKISA 1936
            ++   + ++   Q N  L K R+L+  + + +E  D   +  NK   + R++  ++ A
Sbjct: 1093 QAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEA 1150



 Score = 48.1 bits (113), Expect = 8e-05
 Identities = 58/223 (26%), Positives = 101/223 (45%), Gaps = 29/223 (13%)

Query: 1729 TKKKLENDVSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKN 1788
            TK K    V++ + E++    E +  +E+ +KA         ELK+ +   + L   K  
Sbjct: 839  TKVKPLLQVTRQEEEMQAKEDELQKTKERQQKA-------ENELKELEQKHSQLTEEKNL 891

Query: 1789 LEQTVKDLQHRLDEAEQLALK-GGKKQ-----IQKLEARVRELEGEVENEQKRNAEAVKG 1842
            L++ ++       EAE++ ++   KKQ     + ++EAR   LE E +  Q+  AE    
Sbjct: 892  LQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEAR---LEEEEDRGQQLQAER--- 945

Query: 1843 LRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQAKVKSYKRQAEEAEEQSNANLSKFRKL 1902
             +K  +++ +L  Q EE+     +LQ      +AK+K  + +    ++Q+N  LSK RKL
Sbjct: 946  -KKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNN-KLSKERKL 1003

Query: 1903 QHE--------LEEAEERADIAESQVNKLRVKSREVHTKISAE 1937
              E        L E EE+A       NK      E+  ++  E
Sbjct: 1004 LEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKE 1046


>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
            sapiens]
          Length = 1979

 Score = 1432 bits (3706), Expect = 0.0
 Identities = 789/1916 (41%), Positives = 1188/1916 (62%), Gaps = 34/1916 (1%)

Query: 36   AKTSVFVAEPKESYVKSTIQSKEGGKVTVK-TEGGATLTVREDQVFPMNPPKYDKIEDMA 94
            AK  V+V   K+ +  ++I+ ++G +V V+  E G  +TV +D +  MNPPK+ K+EDMA
Sbjct: 32   AKRLVWVPSEKQGFEAASIKEEKGDEVVVELVENGKKVTVGKDDIQKMNPPKFSKVEDMA 91

Query: 95   MMTHLHEPGVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYKPEVVAAYRGKKRQEAP 154
             +T L+E  VL+NL+ERY + +IYTYSGLFCV VNPYK LP+Y  ++V  Y+GKKR E P
Sbjct: 92   ELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKRHEMP 151

Query: 155  PHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKDES-- 212
            PHI++I+D AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY A +A + + KKD S  
Sbjct: 152  PHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKDTSIT 211

Query: 213  ---GKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETY 269
                   G LE Q++ ANP+LEAFGNAKTV+NDNSSRFGKFIRI+F  TG +  A+IETY
Sbjct: 212  QGPSFAYGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETY 271

Query: 270  LLEKSRVTFQLKAERSYHIFYQITSNKKPDLIEMLLITTNPYDYAFVSQGEITVPSIDDQ 329
            LLEKSR   Q + ER++HIFY + +  K  +   LL+     +Y F+S G + +P+  D 
Sbjct: 272  LLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLE-GFNNYTFLSNGFVPIPAAQDD 330

Query: 330  EELMATDSAIDILGFTPEEKVSIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKAAY 389
            E    T  A+ I+GF+ EE++SI K+  +V+  GN+ FK+++  +QA       A K  +
Sbjct: 331  EMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKVCH 390

Query: 390  LQSLNSADLLKALCYPRVKVGNEYVTKGQTVQQVYNAVGALAKAVYEKMFLWMVTRINQQ 449
            L  +N  D  +++  PR+KVG + V K QT +Q   AV ALAKA YE++F W++TR+N+ 
Sbjct: 391  LMGINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRVNKA 450

Query: 450  LD-TKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEG 508
            LD T +    F+G+LDIAGFEIF+ NS EQLCIN+TNEKLQQ FNH MF+LEQEEY++EG
Sbjct: 451  LDKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREG 510

Query: 509  IEWTFIDFGMDLAACIELIEKPL---GIFSILEEECMFPKATDTSFKNKLYDQHLGKSAN 565
            IEW FIDFG+DL  CIELIE+P    G+ ++L+EEC FPKATD SF  KL  +  G    
Sbjct: 511  IEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQ-GSHPK 569

Query: 566  FQKPKVVKGKAEAHFSLIHYAGTVDYNITGWLDKNKDPLNDTVVGLYQKSAMKTLASLFS 625
            FQKPK +K K E  FS+IHYAG VDYN + WL KN DPLND V  L   S+ K +A L+ 
Sbjct: 570  FQKPKQLKDKTE--FSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLWK 627

Query: 626  TY--------ASAEADSSAKKGAKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCII 677
                       +   +SS    +K K   F+TV  L++E L KLMT LR+T P+FVRCII
Sbjct: 628  DVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCII 687

Query: 678  PNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYGDFKQRYKVLNASAIPEGQ 737
            PN  K  G ++  LVL QLRCNGVLEGIRICR+GFP+RI++ +F+QRY++L A+AIP+G 
Sbjct: 688  PNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKG- 746

Query: 738  FIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDEKLAQIITRTQAVCRG 797
            F+D K+A   ++ ++++D   Y+ G +K+FF+ G+L  LEE RD K+  +I   QA+CRG
Sbjct: 747  FMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRG 806

Query: 798  FLMRVEYQKMLQRREALFCIQYNVRAFMNVKHWPWMKLFFKIKPLLKSAETEKEMATMKE 857
            +L R  + K  Q+  A+  IQ N  A++ +++W W +LF K+KPLL+    E+EM   ++
Sbjct: 807  YLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKED 866

Query: 858  EFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLADAEERCEQLIKNKIQ 917
            E QKTK+   K+E + KELE+K   L +EKN LQ Q+Q+E +  A+AEE   +L   K +
Sbjct: 867  ELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQE 926

Query: 918  LEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENK 977
            LE  + E+  R EEEE+   +L A+++K+  +  +L++ +++ E    K++ EK   E K
Sbjct: 927  LEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAK 986

Query: 978  VKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDKVNILTKAKTKLEQQVDDL 1037
            +K L +E+  +D+   KLSKE+K L+E       +L  EE+K   LTK K K E  + +L
Sbjct: 987  IKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISEL 1046

Query: 1038 EGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQLDEKLEKKEFEISNLISKI 1097
            E  L++E+K R +LE+ KRKLEGD     E   D++    +L  +L KKE E+   ++++
Sbjct: 1047 EVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARL 1106

Query: 1098 EDEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQRSDLSRELEEISERLEEAG 1157
            +DE A +    KKI+EL+  I +L E++++ERA+R KAEKQ+ DL  ELE +   LE+  
Sbjct: 1107 DDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTL 1166

Query: 1158 GATSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRKKHADSMAELGEQIDNLQRVK 1217
             +T+ Q EL  KRE E   L++ L+E T  HEA V  +R+KHA ++ EL EQ++  +R K
Sbjct: 1167 DSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAK 1226

Query: 1218 QKLEKEKSELKMETDDLSSNAEAISKAKGNLEKMCRSLEDQVSELKTKEEEQQRLINDLT 1277
              L+K K  L+ E  DL+     + +AK  +E   + LE QV EL++K  + +R   +L 
Sbjct: 1227 ANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELN 1286

Query: 1278 AQRARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKHQLEEETKAKNALAHALQ 1337
             +  +LQ E    +  L+E +    +L++   + + Q+++ +  L+EET+ K  ++  L+
Sbjct: 1287 DKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLR 1346

Query: 1338 SSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLA 1397
                + + L++Q +EE E K  L+R +S  N +++  + K + D     E LEE KK+  
Sbjct: 1347 QLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQ-DFASTVEALEEGKKRFQ 1405

Query: 1398 QRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLS 1457
            + ++   +  E   A    LEKTK RLQ E++DL++D++      + L+KKQR FD++L+
Sbjct: 1406 KEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLA 1465

Query: 1458 EWK---QKY--EETQAELEASQKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEI 1512
            E K    KY  E  +AE EA +KE+++LS     +    EE+L+  E L R NK L+ E+
Sbjct: 1466 EEKNISSKYADERDRAEAEAREKETKALS-----LARALEEALEAKEELERTNKMLKAEM 1520

Query: 1513 SDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVK 1572
             DL     + GK +HELEK K+ +E +  E++  LEE E  L+  E   LR+++ +  +K
Sbjct: 1521 EDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALK 1580

Query: 1573 SEVDRKIAEKDEEIDQLKRNHTRVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEMEIQL 1632
             + +R +  +DE+ ++ +R   R +   ++ L+ E + R  A   KKK+EGDL ++E+Q 
Sbjct: 1581 GQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQA 1640

Query: 1633 NHANRLAAESLRNYRNTQGILKETQLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELW 1692
            + A +   E+++  R  Q  +K+ Q  L+DA   ++++       E++A  L+A++ +L 
Sbjct: 1641 DSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQ 1700

Query: 1693 ATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQESR 1752
              L   ER+RK A+ E  + +E +    +   +L + K++LE  ++QL+ E+EE      
Sbjct: 1701 EDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNME 1760

Query: 1753 NAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGK 1812
               ++ +KA   A  ++ EL  E+ T+   E  ++ LE+  K+L+ +L E E       K
Sbjct: 1761 AMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFK 1820

Query: 1813 KQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVD 1872
              I  LEA++ +LE +VE E +    A K L++ ++++KE+  Q E++RK   + ++  +
Sbjct: 1821 STIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAE 1880

Query: 1873 KLQAKVKSYKRQAEEAEEQSNANLSKFRKLQHELEEAEERADIAESQVNKLRVKSR 1928
            K  A+VK  KRQ EEAEE+S    +  RKLQ EL+EA E  +    +VN L+ K R
Sbjct: 1881 KGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLR 1936



 Score =  225 bits (574), Expect = 3e-58
 Identities = 201/949 (21%), Positives = 438/949 (46%), Gaps = 57/949 (6%)

Query: 996  SKEKKALQETHQQTLDDLQAEEDKVNILTKAKTKLEQQVDDLE---GSLEQEKKLRMDLE 1052
            +K K  LQ T Q+  +++QA+ED++    + + K E ++ +LE     L +EK L  +  
Sbjct: 846  TKVKPLLQVTRQE--EEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQL 903

Query: 1053 RAKRKLEGDLKLAQESTMDMENDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIK 1112
            +A+ +L  +   A+E  + +   KQ+L+E L + E       +++E+E+    QLQ + K
Sbjct: 904  QAETELYAE---AEEMRVRLAAKKQELEEILHEME-------ARLEEEEDRGQQLQAERK 953

Query: 1113 ELQARIEELGEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQVELNKKREA 1172
            ++  ++ +L E++E E A+R K + ++     +++++ + +           + N K   
Sbjct: 954  KMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEI-------LVMDDQNNKLSK 1006

Query: 1173 EFQKLRRDLEEATLQHEAMVAALRKKHADSMAELGEQIDNLQRVKQKLEKEKSELKMETD 1232
            E + L   + + T                ++AE  E+  NL ++K K E   SEL++   
Sbjct: 1007 ERKLLEERISDLTT---------------NLAEEEEKAKNLTKLKNKHESMISELEVRL- 1050

Query: 1233 DLSSNAEAISKAKGNLEKMCRSLEDQVSELKTKEEEQQRLINDLTAQRARLQTEAGEYSR 1292
                  +   K++  LEK+ R LE   S+   +  + Q  I +L  Q A+ + E      
Sbjct: 1051 ------KKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALA 1104

Query: 1293 QLDEKDALVSQLSRSKQASTQQIEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEE 1352
            +LD++ A  +   +  +     I +L+  L+ E  A+N      +    + + L+ + E+
Sbjct: 1105 RLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELED 1164

Query: 1353 EQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNA 1412
              +  A  Q   +K   EV   +   + +      +++E ++K AQ ++E  E +E    
Sbjct: 1165 TLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKR 1224

Query: 1413 KCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQAELEA 1472
              A+L+K KQ L+ E  DL  ++     A   ++ K++  +  + E + K  + +     
Sbjct: 1225 AKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAE 1284

Query: 1473 SQKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEISDLTEQIAEGGKQIHELEKI 1532
               +   L  E+  V  +  E+  +   L ++  +L  ++ D  E + E  +Q   +   
Sbjct: 1285 LNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTK 1344

Query: 1533 KKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRN 1592
             +Q+E+E+  +Q  L+E   + ++ E  I  + ++L+  K ++ +  A   E +++ K+ 
Sbjct: 1345 LRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKL-QDFASTVEALEEGKKR 1403

Query: 1593 HTRVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEMEIQLNHANRLAAESLRNYRNTQGI 1652
              + +E +    + +  + +   + K +++ +L+++ + L++  +L +   +  R    +
Sbjct: 1404 FQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQL 1463

Query: 1653 LKE----TQLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELWATLEQTERSRKIAEQE 1708
            L E    +  + D+  R + + +E+    E +A  L   +EE     E+ ER+ K+ + E
Sbjct: 1464 LAEEKNISSKYADERDRAEAEAREK----ETKALSLARALEEALEAKEELERTNKMLKAE 1519

Query: 1709 LLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQESRNAEE-KAKKAITDAAM 1767
            + D       +      L  +K+ LE  + ++++++EE+  E +  E+ K +  +   A+
Sbjct: 1520 MEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQAL 1579

Query: 1768 MAEELKKEQDTSAHLERMKKNLEQTVKDLQHRL-DEAEQLALKGGKKQIQKLEARVRELE 1826
              +  +  Q      E  ++ L++ + + +  L DE +Q AL    K+  KLE  +++LE
Sbjct: 1580 KGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKK--KLEGDLKDLE 1637

Query: 1827 GEVENEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQAKVKSYKRQAE 1886
             + ++  K   EA+K LRK + ++K+   + E+ R +   +     + + K KS +    
Sbjct: 1638 LQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLM 1697

Query: 1887 EAEEQSNANLSKFRKLQHELEEAEERADIAESQVNKLRVKSREVHTKIS 1935
            + +E   A     ++   E EE  E    + S  N L+ + R +  +I+
Sbjct: 1698 QLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIA 1746



 Score =  140 bits (352), Expect = 2e-32
 Identities = 121/529 (22%), Positives = 242/529 (45%), Gaps = 19/529 (3%)

Query: 844  KSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLAD 903
            K+A  +K   T K   Q+  D+L      +++L   +    ++ + L  + ++ +   AD
Sbjct: 1418 KAAAYDKLEKT-KNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYAD 1476

Query: 904  AEERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLELT 963
              +R E   + K   E K   +    EE  E   EL    + L+ E  +L    DD+   
Sbjct: 1477 ERDRAEAEAREK---ETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKN 1533

Query: 964  LAKVEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLD-----DLQAEED 1018
            + ++EK K A E +++ +  ++  L++ + + +++ K   E + Q L      DLQA ++
Sbjct: 1534 VHELEKSKRALETQMEEMKTQLEELEDEL-QATEDAKLRLEVNMQALKGQFERDLQARDE 1592

Query: 1019 KVNILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQ 1078
            +     + + +L++Q+ + E  LE E+K R     AK+KLEGDLK  +         +++
Sbjct: 1593 QNE---EKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREE 1649

Query: 1079 LDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQ 1138
              ++L K + ++ +   ++ED +A   ++    KE + + + L  ++   +   A AE+ 
Sbjct: 1650 AIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERA 1709

Query: 1139 RSDLSRELEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRKK 1198
            R     E EE++E L  +    +A  +  ++ EA   +L  +LEE     EAM   +RK 
Sbjct: 1710 RKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKA 1769

Query: 1199 HADSMAELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKA-KGNLEKMCRSLED 1257
                  +L  ++   +   QK E  + +L+ +  +L S    +  A K   +    +LE 
Sbjct: 1770 -TQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEA 1828

Query: 1258 QVSELKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEE 1317
            ++++L+ + E++ R     T    +   +  E   Q++++  +  Q     +    ++++
Sbjct: 1829 KIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQ 1888

Query: 1318 LKHQL---EEETKAKNALAHALQSSRHDCDLLREQYEEEQEG-KAELQR 1362
            LK QL   EEE++  NA    LQ    +     E    E    K++L+R
Sbjct: 1889 LKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLRR 1937



 Score = 76.6 bits (187), Expect = 2e-13
 Identities = 85/358 (23%), Positives = 161/358 (44%), Gaps = 55/358 (15%)

Query: 1591 RNHTRVVETMQSTL-DAEIRSRNDALRVKK----KMEGDLNEME---IQLNHANRLAAES 1642
            R  T+V   +Q T  + E++++ D L+  K    K E +L E+E    QL     L  E 
Sbjct: 843  RLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQ 902

Query: 1643 LRNYRNTQGILKETQLHLDDALRGQEDLKEQLAI----VERRANLLQAEIEELWATLEQT 1698
            L+          ET+L+ +      E+++ +LA     +E   + ++A +EE     +Q 
Sbjct: 903  LQ---------AETELYAE-----AEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQL 948

Query: 1699 ERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQESRNAEEKA 1758
            +  RK   Q++LD  E+++                E + ++ + ++E+V      AE K 
Sbjct: 949  QAERKKMAQQMLDLEEQLE----------------EEEAARQKLQLEKV-----TAEAKI 987

Query: 1759 KKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKL 1818
            KK       + +E+    D +  L + +K LE+ + DL   L E E+ A K   K   K 
Sbjct: 988  KK-------LEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKA-KNLTKLKNKH 1039

Query: 1819 EARVRELEGEVENEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQAKV 1878
            E+ + ELE  ++ E+K   E  K  RK E    +   Q  + +  +  L+  + K + ++
Sbjct: 1040 ESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEEL 1099

Query: 1879 KSYKRQAEEAEEQSNANLSKFRKLQHELEEAEERADIAESQVNKLRVKSREVHTKISA 1936
            ++   + ++   Q N  L K R+L+  + + +E  D   +  NK   + R++  ++ A
Sbjct: 1100 QAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEA 1157



 Score = 48.1 bits (113), Expect = 8e-05
 Identities = 58/223 (26%), Positives = 101/223 (45%), Gaps = 29/223 (13%)

Query: 1729 TKKKLENDVSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKN 1788
            TK K    V++ + E++    E +  +E+ +KA         ELK+ +   + L   K  
Sbjct: 846  TKVKPLLQVTRQEEEMQAKEDELQKTKERQQKA-------ENELKELEQKHSQLTEEKNL 898

Query: 1789 LEQTVKDLQHRLDEAEQLALK-GGKKQ-----IQKLEARVRELEGEVENEQKRNAEAVKG 1842
            L++ ++       EAE++ ++   KKQ     + ++EAR   LE E +  Q+  AE    
Sbjct: 899  LQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEAR---LEEEEDRGQQLQAER--- 952

Query: 1843 LRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQAKVKSYKRQAEEAEEQSNANLSKFRKL 1902
             +K  +++ +L  Q EE+     +LQ      +AK+K  + +    ++Q+N  LSK RKL
Sbjct: 953  -KKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNN-KLSKERKL 1010

Query: 1903 QHE--------LEEAEERADIAESQVNKLRVKSREVHTKISAE 1937
              E        L E EE+A       NK      E+  ++  E
Sbjct: 1011 LEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKE 1053



 Score = 44.3 bits (103), Expect = 0.001
 Identities = 33/174 (18%), Positives = 74/174 (42%), Gaps = 8/174 (4%)

Query: 840  KPLLKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKE-KNDLQLQVQSEA 898
            K   ++ +   E+AT +   QK +    + E + KEL  K+  +    K+  +  + +  
Sbjct: 1768 KATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALE 1827

Query: 899  DSLADAEERCEQLIKNKI-------QLEAKIKEVTERAEEEEEINAELTAKKRKLEDECS 951
              +A  EE+ EQ  + K        Q + K+KE+  + E+E ++  +   +  K      
Sbjct: 1828 AKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVK 1887

Query: 952  ELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQET 1005
            +LK+ +++ E    ++   +   + ++   TE    +   +  L  + +   ET
Sbjct: 1888 QLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLRRGNET 1941


>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
            sapiens]
          Length = 1945

 Score = 1432 bits (3706), Expect = 0.0
 Identities = 789/1916 (41%), Positives = 1188/1916 (62%), Gaps = 34/1916 (1%)

Query: 36   AKTSVFVAEPKESYVKSTIQSKEGGKVTVK-TEGGATLTVREDQVFPMNPPKYDKIEDMA 94
            AK  V+V   K+ +  ++I+ ++G +V V+  E G  +TV +D +  MNPPK+ K+EDMA
Sbjct: 32   AKRLVWVPSEKQGFEAASIKEEKGDEVVVELVENGKKVTVGKDDIQKMNPPKFSKVEDMA 91

Query: 95   MMTHLHEPGVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYKPEVVAAYRGKKRQEAP 154
             +T L+E  VL+NL+ERY + +IYTYSGLFCV VNPYK LP+Y  ++V  Y+GKKR E P
Sbjct: 92   ELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKRHEMP 151

Query: 155  PHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKDES-- 212
            PHI++I+D AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY A +A + + KKD S  
Sbjct: 152  PHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKDTSIT 211

Query: 213  ---GKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETY 269
                   G LE Q++ ANP+LEAFGNAKTV+NDNSSRFGKFIRI+F  TG +  A+IETY
Sbjct: 212  QGPSFAYGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETY 271

Query: 270  LLEKSRVTFQLKAERSYHIFYQITSNKKPDLIEMLLITTNPYDYAFVSQGEITVPSIDDQ 329
            LLEKSR   Q + ER++HIFY + +  K  +   LL+     +Y F+S G + +P+  D 
Sbjct: 272  LLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLE-GFNNYTFLSNGFVPIPAAQDD 330

Query: 330  EELMATDSAIDILGFTPEEKVSIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKAAY 389
            E    T  A+ I+GF+ EE++SI K+  +V+  GN+ FK+++  +QA       A K  +
Sbjct: 331  EMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKVCH 390

Query: 390  LQSLNSADLLKALCYPRVKVGNEYVTKGQTVQQVYNAVGALAKAVYEKMFLWMVTRINQQ 449
            L  +N  D  +++  PR+KVG + V K QT +Q   AV ALAKA YE++F W++TR+N+ 
Sbjct: 391  LMGINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRVNKA 450

Query: 450  LD-TKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEG 508
            LD T +    F+G+LDIAGFEIF+ NS EQLCIN+TNEKLQQ FNH MF+LEQEEY++EG
Sbjct: 451  LDKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREG 510

Query: 509  IEWTFIDFGMDLAACIELIEKPL---GIFSILEEECMFPKATDTSFKNKLYDQHLGKSAN 565
            IEW FIDFG+DL  CIELIE+P    G+ ++L+EEC FPKATD SF  KL  +  G    
Sbjct: 511  IEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQ-GSHPK 569

Query: 566  FQKPKVVKGKAEAHFSLIHYAGTVDYNITGWLDKNKDPLNDTVVGLYQKSAMKTLASLFS 625
            FQKPK +K K E  FS+IHYAG VDYN + WL KN DPLND V  L   S+ K +A L+ 
Sbjct: 570  FQKPKQLKDKTE--FSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLWK 627

Query: 626  TY--------ASAEADSSAKKGAKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCII 677
                       +   +SS    +K K   F+TV  L++E L KLMT LR+T P+FVRCII
Sbjct: 628  DVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCII 687

Query: 678  PNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYGDFKQRYKVLNASAIPEGQ 737
            PN  K  G ++  LVL QLRCNGVLEGIRICR+GFP+RI++ +F+QRY++L A+AIP+G 
Sbjct: 688  PNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKG- 746

Query: 738  FIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDEKLAQIITRTQAVCRG 797
            F+D K+A   ++ ++++D   Y+ G +K+FF+ G+L  LEE RD K+  +I   QA+CRG
Sbjct: 747  FMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRG 806

Query: 798  FLMRVEYQKMLQRREALFCIQYNVRAFMNVKHWPWMKLFFKIKPLLKSAETEKEMATMKE 857
            +L R  + K  Q+  A+  IQ N  A++ +++W W +LF K+KPLL+    E+EM   ++
Sbjct: 807  YLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKED 866

Query: 858  EFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLADAEERCEQLIKNKIQ 917
            E QKTK+   K+E + KELE+K   L +EKN LQ Q+Q+E +  A+AEE   +L   K +
Sbjct: 867  ELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQE 926

Query: 918  LEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENK 977
            LE  + E+  R EEEE+   +L A+++K+  +  +L++ +++ E    K++ EK   E K
Sbjct: 927  LEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAK 986

Query: 978  VKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDKVNILTKAKTKLEQQVDDL 1037
            +K L +E+  +D+   KLSKE+K L+E       +L  EE+K   LTK K K E  + +L
Sbjct: 987  IKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISEL 1046

Query: 1038 EGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQLDEKLEKKEFEISNLISKI 1097
            E  L++E+K R +LE+ KRKLEGD     E   D++    +L  +L KKE E+   ++++
Sbjct: 1047 EVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARL 1106

Query: 1098 EDEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQRSDLSRELEEISERLEEAG 1157
            +DE A +    KKI+EL+  I +L E++++ERA+R KAEKQ+ DL  ELE +   LE+  
Sbjct: 1107 DDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTL 1166

Query: 1158 GATSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRKKHADSMAELGEQIDNLQRVK 1217
             +T+ Q EL  KRE E   L++ L+E T  HEA V  +R+KHA ++ EL EQ++  +R K
Sbjct: 1167 DSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAK 1226

Query: 1218 QKLEKEKSELKMETDDLSSNAEAISKAKGNLEKMCRSLEDQVSELKTKEEEQQRLINDLT 1277
              L+K K  L+ E  DL+     + +AK  +E   + LE QV EL++K  + +R   +L 
Sbjct: 1227 ANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELN 1286

Query: 1278 AQRARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKHQLEEETKAKNALAHALQ 1337
             +  +LQ E    +  L+E +    +L++   + + Q+++ +  L+EET+ K  ++  L+
Sbjct: 1287 DKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLR 1346

Query: 1338 SSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLA 1397
                + + L++Q +EE E K  L+R +S  N +++  + K + D     E LEE KK+  
Sbjct: 1347 QLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQ-DFASTVEALEEGKKRFQ 1405

Query: 1398 QRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLS 1457
            + ++   +  E   A    LEKTK RLQ E++DL++D++      + L+KKQR FD++L+
Sbjct: 1406 KEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLA 1465

Query: 1458 EWK---QKY--EETQAELEASQKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEI 1512
            E K    KY  E  +AE EA +KE+++LS     +    EE+L+  E L R NK L+ E+
Sbjct: 1466 EEKNISSKYADERDRAEAEAREKETKALS-----LARALEEALEAKEELERTNKMLKAEM 1520

Query: 1513 SDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVK 1572
             DL     + GK +HELEK K+ +E +  E++  LEE E  L+  E   LR+++ +  +K
Sbjct: 1521 EDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALK 1580

Query: 1573 SEVDRKIAEKDEEIDQLKRNHTRVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEMEIQL 1632
             + +R +  +DE+ ++ +R   R +   ++ L+ E + R  A   KKK+EGDL ++E+Q 
Sbjct: 1581 GQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQA 1640

Query: 1633 NHANRLAAESLRNYRNTQGILKETQLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELW 1692
            + A +   E+++  R  Q  +K+ Q  L+DA   ++++       E++A  L+A++ +L 
Sbjct: 1641 DSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQ 1700

Query: 1693 ATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQESR 1752
              L   ER+RK A+ E  + +E +    +   +L + K++LE  ++QL+ E+EE      
Sbjct: 1701 EDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNME 1760

Query: 1753 NAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGK 1812
               ++ +KA   A  ++ EL  E+ T+   E  ++ LE+  K+L+ +L E E       K
Sbjct: 1761 AMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFK 1820

Query: 1813 KQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVD 1872
              I  LEA++ +LE +VE E +    A K L++ ++++KE+  Q E++RK   + ++  +
Sbjct: 1821 STIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAE 1880

Query: 1873 KLQAKVKSYKRQAEEAEEQSNANLSKFRKLQHELEEAEERADIAESQVNKLRVKSR 1928
            K  A+VK  KRQ EEAEE+S    +  RKLQ EL+EA E  +    +VN L+ K R
Sbjct: 1881 KGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLR 1936



 Score =  225 bits (574), Expect = 3e-58
 Identities = 201/949 (21%), Positives = 438/949 (46%), Gaps = 57/949 (6%)

Query: 996  SKEKKALQETHQQTLDDLQAEEDKVNILTKAKTKLEQQVDDLE---GSLEQEKKLRMDLE 1052
            +K K  LQ T Q+  +++QA+ED++    + + K E ++ +LE     L +EK L  +  
Sbjct: 846  TKVKPLLQVTRQE--EEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQL 903

Query: 1053 RAKRKLEGDLKLAQESTMDMENDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIK 1112
            +A+ +L  +   A+E  + +   KQ+L+E L + E       +++E+E+    QLQ + K
Sbjct: 904  QAETELYAE---AEEMRVRLAAKKQELEEILHEME-------ARLEEEEDRGQQLQAERK 953

Query: 1113 ELQARIEELGEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQVELNKKREA 1172
            ++  ++ +L E++E E A+R K + ++     +++++ + +           + N K   
Sbjct: 954  KMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEI-------LVMDDQNNKLSK 1006

Query: 1173 EFQKLRRDLEEATLQHEAMVAALRKKHADSMAELGEQIDNLQRVKQKLEKEKSELKMETD 1232
            E + L   + + T                ++AE  E+  NL ++K K E   SEL++   
Sbjct: 1007 ERKLLEERISDLTT---------------NLAEEEEKAKNLTKLKNKHESMISELEVRL- 1050

Query: 1233 DLSSNAEAISKAKGNLEKMCRSLEDQVSELKTKEEEQQRLINDLTAQRARLQTEAGEYSR 1292
                  +   K++  LEK+ R LE   S+   +  + Q  I +L  Q A+ + E      
Sbjct: 1051 ------KKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALA 1104

Query: 1293 QLDEKDALVSQLSRSKQASTQQIEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEE 1352
            +LD++ A  +   +  +     I +L+  L+ E  A+N      +    + + L+ + E+
Sbjct: 1105 RLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELED 1164

Query: 1353 EQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNA 1412
              +  A  Q   +K   EV   +   + +      +++E ++K AQ ++E  E +E    
Sbjct: 1165 TLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKR 1224

Query: 1413 KCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQAELEA 1472
              A+L+K KQ L+ E  DL  ++     A   ++ K++  +  + E + K  + +     
Sbjct: 1225 AKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAE 1284

Query: 1473 SQKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEISDLTEQIAEGGKQIHELEKI 1532
               +   L  E+  V  +  E+  +   L ++  +L  ++ D  E + E  +Q   +   
Sbjct: 1285 LNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTK 1344

Query: 1533 KKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRN 1592
             +Q+E+E+  +Q  L+E   + ++ E  I  + ++L+  K ++ +  A   E +++ K+ 
Sbjct: 1345 LRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKL-QDFASTVEALEEGKKR 1403

Query: 1593 HTRVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEMEIQLNHANRLAAESLRNYRNTQGI 1652
              + +E +    + +  + +   + K +++ +L+++ + L++  +L +   +  R    +
Sbjct: 1404 FQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQL 1463

Query: 1653 LKE----TQLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELWATLEQTERSRKIAEQE 1708
            L E    +  + D+  R + + +E+    E +A  L   +EE     E+ ER+ K+ + E
Sbjct: 1464 LAEEKNISSKYADERDRAEAEAREK----ETKALSLARALEEALEAKEELERTNKMLKAE 1519

Query: 1709 LLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQESRNAEE-KAKKAITDAAM 1767
            + D       +      L  +K+ LE  + ++++++EE+  E +  E+ K +  +   A+
Sbjct: 1520 MEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQAL 1579

Query: 1768 MAEELKKEQDTSAHLERMKKNLEQTVKDLQHRL-DEAEQLALKGGKKQIQKLEARVRELE 1826
              +  +  Q      E  ++ L++ + + +  L DE +Q AL    K+  KLE  +++LE
Sbjct: 1580 KGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKK--KLEGDLKDLE 1637

Query: 1827 GEVENEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQAKVKSYKRQAE 1886
             + ++  K   EA+K LRK + ++K+   + E+ R +   +     + + K KS +    
Sbjct: 1638 LQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLM 1697

Query: 1887 EAEEQSNANLSKFRKLQHELEEAEERADIAESQVNKLRVKSREVHTKIS 1935
            + +E   A     ++   E EE  E    + S  N L+ + R +  +I+
Sbjct: 1698 QLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIA 1746



 Score = 76.6 bits (187), Expect = 2e-13
 Identities = 85/358 (23%), Positives = 161/358 (44%), Gaps = 55/358 (15%)

Query: 1591 RNHTRVVETMQSTL-DAEIRSRNDALRVKK----KMEGDLNEME---IQLNHANRLAAES 1642
            R  T+V   +Q T  + E++++ D L+  K    K E +L E+E    QL     L  E 
Sbjct: 843  RLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQ 902

Query: 1643 LRNYRNTQGILKETQLHLDDALRGQEDLKEQLAI----VERRANLLQAEIEELWATLEQT 1698
            L+          ET+L+ +      E+++ +LA     +E   + ++A +EE     +Q 
Sbjct: 903  LQ---------AETELYAE-----AEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQL 948

Query: 1699 ERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQESRNAEEKA 1758
            +  RK   Q++LD  E+++                E + ++ + ++E+V      AE K 
Sbjct: 949  QAERKKMAQQMLDLEEQLE----------------EEEAARQKLQLEKV-----TAEAKI 987

Query: 1759 KKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKL 1818
            KK       + +E+    D +  L + +K LE+ + DL   L E E+ A K   K   K 
Sbjct: 988  KK-------LEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKA-KNLTKLKNKH 1039

Query: 1819 EARVRELEGEVENEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQAKV 1878
            E+ + ELE  ++ E+K   E  K  RK E    +   Q  + +  +  L+  + K + ++
Sbjct: 1040 ESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEEL 1099

Query: 1879 KSYKRQAEEAEEQSNANLSKFRKLQHELEEAEERADIAESQVNKLRVKSREVHTKISA 1936
            ++   + ++   Q N  L K R+L+  + + +E  D   +  NK   + R++  ++ A
Sbjct: 1100 QAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEA 1157



 Score = 48.1 bits (113), Expect = 8e-05
 Identities = 58/223 (26%), Positives = 101/223 (45%), Gaps = 29/223 (13%)

Query: 1729 TKKKLENDVSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKN 1788
            TK K    V++ + E++    E +  +E+ +KA         ELK+ +   + L   K  
Sbjct: 846  TKVKPLLQVTRQEEEMQAKEDELQKTKERQQKA-------ENELKELEQKHSQLTEEKNL 898

Query: 1789 LEQTVKDLQHRLDEAEQLALK-GGKKQ-----IQKLEARVRELEGEVENEQKRNAEAVKG 1842
            L++ ++       EAE++ ++   KKQ     + ++EAR   LE E +  Q+  AE    
Sbjct: 899  LQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEAR---LEEEEDRGQQLQAER--- 952

Query: 1843 LRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQAKVKSYKRQAEEAEEQSNANLSKFRKL 1902
             +K  +++ +L  Q EE+     +LQ      +AK+K  + +    ++Q+N  LSK RKL
Sbjct: 953  -KKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNN-KLSKERKL 1010

Query: 1903 QHE--------LEEAEERADIAESQVNKLRVKSREVHTKISAE 1937
              E        L E EE+A       NK      E+  ++  E
Sbjct: 1011 LEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKE 1053


>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
          Length = 1960

 Score = 1410 bits (3651), Expect = 0.0
 Identities = 778/1912 (40%), Positives = 1180/1912 (61%), Gaps = 36/1912 (1%)

Query: 36   AKTSVFVAEPKESYVKSTIQSKEGGKVTVK-TEGGATLTVREDQVFPMNPPKYDKIEDMA 94
            AK  V+V   K  +  ++++ + G +  V+  E G  + V +D +  MNPPK+ K+EDMA
Sbjct: 28   AKKLVWVPSDKSGFEPASLKEEVGEEAIVELVENGKKVKVNKDDIQKMNPPKFSKVEDMA 87

Query: 95   MMTHLHEPGVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYKPEVVAAYRGKKRQEAP 154
             +T L+E  VL+NLKERY + +IYTYSGLFCV +NPYK LP+Y  E+V  Y+GKKR E P
Sbjct: 88   ELTCLNEASVLHNLKERYYSGLIYTYSGLFCVVINPYKNLPIYSEEIVEMYKGKKRHEMP 147

Query: 155  PHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKDESGK 214
            PHI++I+D AY+ M+ DRE+QSIL TGESGAGKT NTK+VIQY A +A + + KKD    
Sbjct: 148  PHIYAITDTAYRSMMQDREDQSILCTGESGAGKTENTKKVIQYLAYVASSHKSKKD---- 203

Query: 215  MQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLEKS 274
             QG LE Q++ ANP+LEAFGNAKTV+NDNSSRFGKFIRI+F   G +  A+IETYLLEKS
Sbjct: 204  -QGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVNGYIVGANIETYLLEKS 262

Query: 275  RVTFQLKAERSYHIFYQITSNKKPDLIEMLLITTNPYD-YAFVSQGEITVPSIDDQEELM 333
            R   Q K ER++HIFY + S     L   LL+   PY+ Y F+S G +T+P   D++   
Sbjct: 263  RAIRQAKEERTFHIFYYLLSGAGEHLKTDLLL--EPYNKYRFLSNGHVTIPGQQDKDMFQ 320

Query: 334  ATDSAIDILGFTPEEKVSIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKAAYLQSL 393
             T  A+ I+G   EE++ + ++   V+  GN+ FK+++  +QA       A K ++L  +
Sbjct: 321  ETMEAMRIMGIPEEEQMGLLRVISGVLQLGNIVFKKERNTDQASMPDNTAAQKVSHLLGI 380

Query: 394  NSADLLKALCYPRVKVGNEYVTKGQTVQQVYNAVGALAKAVYEKMFLWMVTRINQQLD-T 452
            N  D  + +  PR+KVG +YV K QT +Q   A+ ALAKA YE+MF W+V RIN+ LD T
Sbjct: 381  NVTDFTRGILTPRIKVGRDYVQKAQTKEQADFAIEALAKATYERMFRWLVLRINKALDKT 440

Query: 453  KQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWT 512
            K+    FIG+LDIAGFEIFD NS EQLCIN+TNEKLQQ FNH MF+LEQEEY++EGIEW 
Sbjct: 441  KRQGASFIGILDIAGFEIFDLNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWN 500

Query: 513  FIDFGMDLAACIELIEKPLG---IFSILEEECMFPKATDTSFKNKLYDQHLGKSANFQKP 569
            FIDFG+DL  CI+LIEKP G   I ++L+EEC FPKATD SF  K+  Q  G    FQKP
Sbjct: 501  FIDFGLDLQPCIDLIEKPAGPPGILALLDEECWFPKATDKSFVEKVM-QEQGTHPKFQKP 559

Query: 570  KVVKGKAEAHFSLIHYAGTVDYNITGWLDKNKDPLNDTVVGLYQKSAMKTLASLFSTYAS 629
            K +K KA+  F +IHYAG VDY    WL KN DPLND +  L  +S+ K ++ L+     
Sbjct: 560  KQLKDKAD--FCIIHYAGKVDYKADEWLMKNMDPLNDNIATLLHQSSDKFVSELWKDVDR 617

Query: 630  -------AEADSSAKKGA-KKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPNET 681
                   A    +A  GA K +   F+TV  L++E L KLM  LR+T+P+FVRCIIPN  
Sbjct: 618  IIGLDQVAGMSETALPGAFKTRKGMFRTVGQLYKEQLAKLMATLRNTNPNFVRCIIPNHE 677

Query: 682  KTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYGDFKQRYKVLNASAIPEGQFIDS 741
            K  G ++  LVL QLRCNGVLEGIRICR+GFP+R+++ +F+QRY++L  ++IP+G F+D 
Sbjct: 678  KKAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRVVFQEFRQRYEILTPNSIPKG-FMDG 736

Query: 742  KKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDEKLAQIITRTQAVCRGFLMR 801
            K+A   ++ ++++D   Y+ G +KVFF+AG+L  LEE RD K+  +I   QA CRG+L R
Sbjct: 737  KQACVLMIKALELDSNLYRIGQSKVFFRAGVLAHLEEERDLKITDVIIGFQACCRGYLAR 796

Query: 802  VEYQKMLQRREALFCIQYNVRAFMNVKHWPWMKLFFKIKPLLKSAETEKEMATMKEEFQK 861
              + K  Q+  A+  +Q N  A++ +++W W +LF K+KPLL+ +  E+EM   +EE  K
Sbjct: 797  KAFAKRQQQLTAMKVLQRNCAAYLKLRNWQWWRLFTKVKPLLQVSRQEEEMMAKEEELVK 856

Query: 862  TKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLADAEERCEQLIKNKIQLEAK 921
             +++   +E +  E+E     L+ EK  LQ Q+Q+E +  A+AEE   +L   K +LE  
Sbjct: 857  VREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEELRARLTAKKQELEEI 916

Query: 922  IKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNL 981
              ++  R EEEEE    L A+K+K++    EL++ +++ E    K++ EK  TE K+K L
Sbjct: 917  CHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKL 976

Query: 982  TEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDKVNILTKAKTKLEQQVDDLEGSL 1041
             EE   L++   KL+KEKK L++   +   +L  EE+K   L K K K E  + DLE  L
Sbjct: 977  EEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERL 1036

Query: 1042 EQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQLDEKLEKKEFEISNLISKIEDEQ 1101
             +E+K R +LE+ +RKLEGD     +   +++    +L  +L KKE E+   ++++E+E 
Sbjct: 1037 RREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEA 1096

Query: 1102 AVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATS 1161
            A +    KKI+EL+++I EL E++E+ERASR KAEKQ+ DL  ELE +   LE+   +T+
Sbjct: 1097 AQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTA 1156

Query: 1162 AQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRKKHADSMAELGEQIDNLQRVKQKLE 1221
            AQ EL  KRE E   L++ LEE    HEA +  +R+KH+ ++ EL EQ++  +RVK  LE
Sbjct: 1157 AQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLE 1216

Query: 1222 KEKSELKMETDDLSSNAEAISKAKGNLEKMCRSLEDQVSELKTKEEEQQRLINDLTAQRA 1281
            K K  L+ E  +L++  + + + KG+ E   + +E Q+ EL+ K  E +R+  +L  +  
Sbjct: 1217 KAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVT 1276

Query: 1282 RLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKHQLEEETKAKNALAHALQSSRH 1341
            +LQ E    +  L + D+  S+L++   A   Q+++ +  L+EE + K +L+  L+    
Sbjct: 1277 KLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVED 1336

Query: 1342 DCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQ 1401
            + +  REQ EEE+E K  L++ ++  +++VA  + K E D++   E  EE K+KL + L+
Sbjct: 1337 EKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKME-DSVGCLETAEEVKRKLQKDLE 1395

Query: 1402 EAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWK- 1460
               +  E   A    LEKTK RLQ E++DL++D++    +   L+KKQ+ FD++L+E K 
Sbjct: 1396 GLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKT 1455

Query: 1461 --QKY--EETQAELEASQKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEISDLT 1516
               KY  E  +AE EA +KE+++LS     +    EE+++Q   L R NK  + E+ DL 
Sbjct: 1456 ISAKYAEERDRAEAEAREKETKALS-----LARALEEAMEQKAELERLNKQFRTEMEDLM 1510

Query: 1517 EQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEVD 1576
                + GK +HELEK K+ +EQ+  E++  LEE E  L+  E   LR+++ L  +K++ +
Sbjct: 1511 SSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFE 1570

Query: 1577 RKIAEKDEEIDQLKRNHTRVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEMEIQLNHAN 1636
            R +  +DE+ ++ K+   R V  M++ L+ E + R+ A+  +KK+E DL ++E  ++ AN
Sbjct: 1571 RDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSAN 1630

Query: 1637 RLAAESLRNYRNTQGILKETQLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELWATLE 1696
            +   E+++  R  Q  +K+    LDD    +E++  Q    E++   ++AE+ +L   L 
Sbjct: 1631 KNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELA 1690

Query: 1697 QTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQESRNAEE 1756
              ER+++ A+QE  + ++ +     +    +  K++LE  ++QL+ E+EE    +    +
Sbjct: 1691 AAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELIND 1750

Query: 1757 KAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQ 1816
            + KKA      +  +L  E+  +   E  ++ LE+  K+L+ +L E E       K  I 
Sbjct: 1751 RLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKASIT 1810

Query: 1817 KLEARVRELEGEVENEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQA 1876
             LEA++ +LE +++NE K    A K +R+ E+++K++  Q +++R+N  + +D  DK   
Sbjct: 1811 ALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKAST 1870

Query: 1877 KVKSYKRQAEEAEEQSNANLSKFRKLQHELEEAEERADIAESQVNKLRVKSR 1928
            ++K  KRQ EEAEE++    +  RKLQ ELE+A E AD    +V+ L+ K R
Sbjct: 1871 RLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETADAMNREVSSLKNKLR 1922



 Score =  260 bits (665), Expect = 8e-69
 Identities = 236/983 (24%), Positives = 458/983 (46%), Gaps = 103/983 (10%)

Query: 847  ETEKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTL-------LKEKNDLQLQVQSEAD 899
            E E+++   +   QK + E   +EAK K+LEE+ + L        KEK  L+ ++     
Sbjct: 947  ELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTT 1006

Query: 900  SLADAEERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLE-------DECSE 952
            +L + EE+ + L K K + EA I ++ ER   EE+   EL   +RKLE       D+ +E
Sbjct: 1007 NLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAE 1066

Query: 953  LKKDIDDLELTLAKVEKE--------------KHATENKVKNLTEEMAGLDETIAK---- 994
            L+  I +L++ LAK E+E              K+    K++ L  +++ L E +      
Sbjct: 1067 LQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERAS 1126

Query: 995  ----------LSKEKKALQETHQQTLDDLQAE-------EDKVNILTK-----AKT---- 1028
                      L +E +AL+   + TLD   A+       E +VNIL K     AKT    
Sbjct: 1127 RNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQ 1186

Query: 1029 ------KLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDL-KLAQESTMDMENDKQQLDE 1081
                  K  Q V++L   LEQ K+++ +LE+AK+ LE +  +LA E  + ++  K   + 
Sbjct: 1187 IQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQG-KGDSEH 1245

Query: 1082 KLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQRSD 1141
            K +K E ++  L  K  + + V  +L  K+ +LQ  ++ +   +    +  +K  K  S 
Sbjct: 1246 KRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSA 1305

Query: 1142 LSRELEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEE------------ATLQHE 1189
            L  +L++  E L+E      +     K+ E E    R  LEE            ATL   
Sbjct: 1306 LESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLH-- 1363

Query: 1190 AMVAALRKKHADSMA--ELGEQID-----NLQRVKQ----------KLEKEKSELKMETD 1232
            A VA ++KK  DS+   E  E++      +L+ + Q          KLEK K+ L+ E D
Sbjct: 1364 AQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELD 1423

Query: 1233 DLSSNAEAISKAKGNLEKMCRSLEDQVSELKTKEEEQQRLINDLTAQRARLQTEAGEYSR 1292
            DL  + +   ++  NLEK  +  +  ++E KT   +     +   A+    +T+A   +R
Sbjct: 1424 DLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLAR 1483

Query: 1293 QLDEKDALVSQLSRSKQASTQQIEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEE 1352
             L+E     ++L R  +    ++E+L    ++  K+ + L  + ++     + ++ Q EE
Sbjct: 1484 ALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEE 1543

Query: 1353 EQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNA 1412
             ++     + A  +    +   + ++E D   R E+ EE KK+L ++++E E  +E    
Sbjct: 1544 LEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERK 1603

Query: 1413 KCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQAELEA 1472
            + +     +++L+ +++DL   ++ +N       K+ R     + +  ++ ++T+A  E 
Sbjct: 1604 QRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREE 1663

Query: 1473 SQKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEISDLTEQIAEG-GKQIHELEK 1531
               +++    +L  ++    +  ++L    R  +  QQE  +L ++IA   GK    LE+
Sbjct: 1664 ILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEE 1723

Query: 1532 IKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEV--DRKIAEKDEEIDQL 1589
             K+++E    +++  LEE + + E    ++ +  L+++Q+ +++  +R  A+K+E   Q 
Sbjct: 1724 -KRRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQ 1782

Query: 1590 KRNHTRVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEMEIQLNHANRLAAESLRNYRNT 1649
                 + ++     ++  ++S+  A      +E  + ++E QL++  +    + +  R T
Sbjct: 1783 LERQNKELKVKLQEMEGTVKSKYKASITA--LEAKIAQLEEQLDNETKERQAACKQVRRT 1840

Query: 1650 QGILKETQLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELWATLEQTERSRKIAEQEL 1709
            +  LK+  L +DD  R  E  K+Q      R   L+ ++EE     ++   SR+  ++EL
Sbjct: 1841 EKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQREL 1900

Query: 1710 LDASERVQLLHTQNTSLINTKKK 1732
             DA+E    ++ + +SL N  ++
Sbjct: 1901 EDATETADAMNREVSSLKNKLRR 1923



 Score =  240 bits (612), Expect = 1e-62
 Identities = 211/981 (21%), Positives = 459/981 (46%), Gaps = 82/981 (8%)

Query: 996  SKEKKALQETHQQTLDDLQAEEDKVNILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAK 1055
            +K K  LQ + Q+  +++ A+E+++        K+ ++    E  L + + L+  L   K
Sbjct: 832  TKVKPLLQVSRQE--EEMMAKEEEL-------VKVREKQLAAENRLTEMETLQSQLMAEK 882

Query: 1056 RKLEGDLKLAQESTMDMENDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQ 1115
             +L+  L+   E   + E  + +L  K ++ E    +L +++E+E+     LQ + K++Q
Sbjct: 883  LQLQEQLQAETELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQ 942

Query: 1116 ARIEELGEEIEAERASRAKAEKQRSDLSRELEEISER---LEEAGGATSAQVELNKKREA 1172
              I+EL E++E E ++R K + ++     +L+++ E    LE+     + + +L + R A
Sbjct: 943  QNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIA 1002

Query: 1173 EFQKLRRDLEEATLQHEAMVAALRKKHADSMAELGEQIDNLQRVKQKLEKEKSELKMETD 1232
            EF     + EE +      +A L+ KH   + +L E++   ++ +Q+LEK + +L+ ++ 
Sbjct: 1003 EFTTNLTEEEEKSKS----LAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDST 1058

Query: 1233 DLSSNAEAISKAKGNLEKMCRSLEDQVSELKTKEEEQQRLINDLTAQRARLQTEAGEYSR 1292
            DLS                   L+ Q++ELK +  +++    +L A  AR++ EA + + 
Sbjct: 1059 DLSDQIA--------------ELQAQIAELKMQLAKKEE---ELQAALARVEEEAAQKNM 1101

Query: 1293 QLDEKDALVSQLSRSKQASTQQIEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEE 1352
             L +   L SQ+S           EL+  LE E  ++N      +    + + L+ + E+
Sbjct: 1102 ALKKIRELESQIS-----------ELQEDLESERASRNKAEKQKRDLGEELEALKTELED 1150

Query: 1353 EQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNA 1412
              +  A  Q   SK   EV   +   E +A     +++E ++K +Q ++E  E +E    
Sbjct: 1151 TLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKR 1210

Query: 1413 KCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQAELEA 1472
              A+LEK KQ L+NE  +L  +V+         + K++  +  L E + K+ E +     
Sbjct: 1211 VKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTE 1270

Query: 1473 SQKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEISDLTEQIAEGGKQIHELEKI 1532
               +   L  EL  V  +  +S  +   L ++   L+ ++ D  E + E  +Q   L   
Sbjct: 1271 LADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTK 1330

Query: 1533 KKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRN 1592
             KQVE EK   +  LEE E +  + E +I  +  ++  +K +++  +    E  +++KR 
Sbjct: 1331 LKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCL-ETAEEVKRK 1389

Query: 1593 HTRVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEMEIQLNHANRLAAESLRNYRNTQGI 1652
              + +E +    + ++ + +   + K +++ +L+++ + L+H  + A    +  +    +
Sbjct: 1390 LQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQL 1449

Query: 1653 L---------------------KETQLHLDDALRGQEDLKEQLAIVERRANLLQAEIEEL 1691
            L                     +E +       R  E+  EQ A +ER     + E+E+L
Sbjct: 1450 LAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDL 1509

Query: 1692 WAT-------LEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEV 1744
             ++       + + E+S++  EQ++ +   +++ L  +  +  + K +LE ++  ++++ 
Sbjct: 1510 MSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQF 1569

Query: 1745 EEVIQ-ESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEA 1803
            E  +Q     +EEK K+ +     M  EL+ E+   +     +K LE  +KDL+  +D A
Sbjct: 1570 ERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSA 1629

Query: 1804 EQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHERRVKELT---YQTEED 1860
             +   +   KQ++KL+A++++   E+++ +    E +   +++E+++K +     Q +E+
Sbjct: 1630 NKNRDEA-IKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEE 1688

Query: 1861 RKNVLRL----QDLVDKLQAKVKSYKRQAEEAEEQSNANLSKFRKLQHELEEAEERADIA 1916
                 R     Q   D+L  ++ +   +   A E+     ++  +L+ ELEE +   ++ 
Sbjct: 1689 LAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELI 1748

Query: 1917 ESQVNKLRVKSREVHTKISAE 1937
              ++ K  ++  +++T ++ E
Sbjct: 1749 NDRLKKANLQIDQINTDLNLE 1769



 Score =  122 bits (305), Expect = 4e-27
 Identities = 124/584 (21%), Positives = 253/584 (43%), Gaps = 61/584 (10%)

Query: 1374 WRTKYETDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLML 1433
            WR   +   + +    EE      + L +  E   A   +   +E  + +L  E   L  
Sbjct: 828  WRLFTKVKPLLQVSRQEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQE 887

Query: 1434 DVERSNAACAALDKKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELFKVKNVYEE 1493
             ++     CA  ++ +      L+  KQ+ EE   +LEA                   EE
Sbjct: 888  QLQAETELCAEAEELRAR----LTAKKQELEEICHDLEAR-----------------VEE 926

Query: 1494 SLDQLETLRRENKNLQQEISDLTEQIAE--GGKQIHELEKIKKQVEQEKCEIQAALEEAE 1551
              ++ + L+ E K +QQ I +L EQ+ E    +Q  +LEK+  + + +K      LEE +
Sbjct: 927  EEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKK------LEEEQ 980

Query: 1552 ASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEE---IDQLKRNHTRVVETMQSTLDAEI 1608
              LE +  K+ + +  L    +E    + E++E+   + +LK  H  ++  ++  L  E 
Sbjct: 981  IILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREE 1040

Query: 1609 RSRNDALRVKKKMEGDLNEMEIQLNHANRLAAESLRNYRNTQGILKETQLHLDDALRGQE 1668
            + R +  + ++K+EGD  ++  Q+       AE           L + +  L  AL   E
Sbjct: 1041 KQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQ-------LAKKEEELQAALARVE 1093

Query: 1669 DLKEQLAIVERRANLLQAEIEELWATLEQTERSRKIAEQELLDASERVQLLHTQNTSLIN 1728
            +   Q  +  ++   L+++I EL   LE    SR  AE++  D  E ++ L T+    ++
Sbjct: 1094 EEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLD 1153

Query: 1729 T-------KKKLENDVSQLQSEVEEVIQ-ESRNAEEKAKKAITDAAMMAEELKKEQDTSA 1780
            +       + K E +V+ L+  +EE  +      +E  +K       +AE+L++ +   A
Sbjct: 1154 STAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKA 1213

Query: 1781 HLERMKKNLEQTVKDLQHRLDEAEQLALKG---GKKQIQKLEARVRELEGEVENEQKRNA 1837
            +LE+ K+ LE    +L + +    ++ L+G    + + +K+EA+++EL+ +    ++   
Sbjct: 1214 NLEKAKQTLENERGELANEV----KVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRT 1269

Query: 1838 EAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQAKVKSYKRQAEEAEEQSNANLS 1897
            E    + K +  +  +T    +      +L      L+++++  +   +E   Q  +  +
Sbjct: 1270 ELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLST 1329

Query: 1898 KFRKLQHE-------LEEAEERADIAESQVNKLRVKSREVHTKI 1934
            K ++++ E       LEE EE     E Q+  L  +  ++  K+
Sbjct: 1330 KLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKM 1373


>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
          Length = 1976

 Score = 1407 bits (3643), Expect = 0.0
 Identities = 772/1918 (40%), Positives = 1188/1918 (61%), Gaps = 31/1918 (1%)

Query: 29   AQNKPFDAKTSVFVAEPKESYVKSTIQSKEGGKVTVK-TEGGATLTVREDQVFPMNPPKY 87
            A    + AK  V++   +  +  ++I+ + G +V V+  E G    V +D +  MNPPK+
Sbjct: 25   ATQADWTAKKLVWIPSERHGFEAASIKEERGDEVMVELAENGKKAMVNKDDIQKMNPPKF 84

Query: 88   DKIEDMAMMTHLHEPGVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYKPEVVAAYRG 147
             K+EDMA +T L+E  VL+NLK+RY + +IYTYSGLFCV +NPYK LP+Y   ++  YRG
Sbjct: 85   SKVEDMAELTCLNEASVLHNLKDRYYSGLIYTYSGLFCVVINPYKNLPIYSENIIEMYRG 144

Query: 148  KKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEK 207
            KKR E PPHI++IS++AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY A +A + + 
Sbjct: 145  KKRHEMPPHIYAISESAYRCMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSHKG 204

Query: 208  KKDESGKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIE 267
            +KD +  + G LE Q++ ANP+LE+FGNAKTV+NDNSSRFGKFIRI+F  TG +  A+IE
Sbjct: 205  RKDHN--IPGELERQLLQANPILESFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIE 262

Query: 268  TYLLEKSRVTFQLKAERSYHIFYQITSNKKPDLIEMLLITTNPYDYAFVSQGEITVPSID 327
            TYLLEKSR   Q K ER++HIFYQ+ S     L   LL+     +Y F+S G I +P   
Sbjct: 263  TYLLEKSRAVRQAKDERTFHIFYQLLSGAGEHLKSDLLLE-GFNNYRFLSNGYIPIPGQQ 321

Query: 328  DQEELMATDSAIDILGFTPEEKVSIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKA 387
            D++    T  A+ I+GF+ EE +S+ K+  +V+ +GN+ FK+++  +QA      VA K 
Sbjct: 322  DKDNFQETMEAMHIMGFSHEEILSMLKVVSSVLQFGNISFKKERNTDQASMPENTVAQKL 381

Query: 388  AYLQSLNSADLLKALCYPRVKVGNEYVTKGQTVQQVYNAVGALAKAVYEKMFLWMVTRIN 447
             +L  +N  +  +A+  PR+KVG +YV K QT +Q   AV ALAKA YE++F W+V RIN
Sbjct: 382  CHLLGMNVMEFTRAILTPRIKVGRDYVQKAQTKEQADFAVEALAKATYERLFRWLVHRIN 441

Query: 448  QQLD-TKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKK 506
            + LD TK+    FIG+LDIAGFEIF+ NS EQLCIN+TNEKLQQ FNH MF+LEQEEY++
Sbjct: 442  KALDRTKRQGASFIGILDIAGFEIFELNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQR 501

Query: 507  EGIEWTFIDFGMDLAACIELIEKPL---GIFSILEEECMFPKATDTSFKNKLYDQHLGKS 563
            EGIEW FIDFG+DL  CI+LIE+P    G+ ++L+EEC FPKATD +F  KL  Q  G  
Sbjct: 502  EGIEWNFIDFGLDLQPCIDLIERPANPPGVLALLDEECWFPKATDKTFVEKLV-QEQGSH 560

Query: 564  ANFQKPKVVKGKAEAHFSLIHYAGTVDYNITGWLDKNKDPLNDTVVGLYQKSAMKTLASL 623
            + FQKP+ +K KA+  F +IHYAG VDY    WL KN DPLND V  L  +S+ + +A L
Sbjct: 561  SKFQKPRQLKDKAD--FCIIHYAGKVDYKADEWLMKNMDPLNDNVATLLHQSSDRFVAEL 618

Query: 624  FSTY--------ASAEADSSAKKGAKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRC 675
            +            +   +++     K K   F+TV  L++E+L KLM  LR+T+P+FVRC
Sbjct: 619  WKDVDRIVGLDQVTGMTETAFGSAYKTKKGMFRTVGQLYKESLTKLMATLRNTNPNFVRC 678

Query: 676  IIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYGDFKQRYKVLNASAIPE 735
            IIPN  K  G ++  LVL QLRCNGVLEGIRICR+GFP+RI++ +F+QRY++L  +AIP+
Sbjct: 679  IIPNHEKRAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILTPNAIPK 738

Query: 736  GQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDEKLAQIITRTQAVC 795
            G F+D K+A E+++ ++++D   Y+ G +K+FF+AG+L  LEE RD K+  II   QAVC
Sbjct: 739  G-FMDGKQACERMIRALELDPNLYRIGQSKIFFRAGVLAHLEEERDLKITDIIIFFQAVC 797

Query: 796  RGFLMRVEYQKMLQRREALFCIQYNVRAFMNVKHWPWMKLFFKIKPLLKSAETEKEMATM 855
            RG+L R  + K  Q+  AL  +Q N  A++ ++HW W ++F K+KPLL+    E+E+   
Sbjct: 798  RGYLARKAFAKKQQQLSALKVLQRNCAAYLKLRHWQWWRVFTKVKPLLQVTRQEEELQAK 857

Query: 856  KEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLADAEERCEQLIKNK 915
             EE  K K++  K E + +E+E K   LL+EKN L  Q+Q+E +  A+AEE   +L   K
Sbjct: 858  DEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMRARLAAKK 917

Query: 916  IQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATE 975
             +LE  + ++  R EEEEE N  L  +K+K++    +L++ +D+ E    K++ EK   E
Sbjct: 918  QELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEKVTAE 977

Query: 976  NKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDKVNILTKAKTKLEQQVD 1035
             K+K + EE+  L++  +K  KEKK +++   +    L  EE+K   L K + K E  + 
Sbjct: 978  AKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMIS 1037

Query: 1036 DLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQLDEKLEKKEFEISNLIS 1095
            DLE  L++E+K R +LE+AKRKL+G+    Q+   +++    +L  +L KKE E+   ++
Sbjct: 1038 DLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGALA 1097

Query: 1096 KIEDEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQRSDLSRELEEISERLEE 1155
            + +DE   +    K ++ELQA+I EL E+ E+E+ASR KAEKQ+ DLS ELE +   LE+
Sbjct: 1098 RGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELED 1157

Query: 1156 AGGATSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRKKHADSMAELGEQIDNLQR 1215
                T+AQ EL  KRE E  +L++ LEE T  HEA +  +R++HA ++ EL EQ++  +R
Sbjct: 1158 TLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKR 1217

Query: 1216 VKQKLEKEKSELKMETDDLSSNAEAISKAKGNLEKMCRSLEDQVSELKTKEEEQQRLIND 1275
             K  LEK K  L+ +  +L+   + + + K   E   + L+ QV EL  K  E  RL  +
Sbjct: 1218 FKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVE 1277

Query: 1276 LTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKHQLEEETKAKNALAHA 1335
            L  + ++LQ E    S  L+E +    + ++   +   Q+++ +  L+EET+ K  L+  
Sbjct: 1278 LAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSR 1337

Query: 1336 LQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKK 1395
            ++    + + L+EQ EEE+E +  L++ +    S++A  + K + D +   E LEEAKKK
Sbjct: 1338 IRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDD-LGTIESLEEAKKK 1396

Query: 1396 LAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKV 1455
            L +  +   + +E        LEKTK RLQ E++DL +D++      + L+KKQ+ FD++
Sbjct: 1397 LLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQL 1456

Query: 1456 LSEWKQ---KY--EETQAELEASQKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQ 1510
            L+E K    +Y  E  +AE EA +KE+++LS     +    EE+L+  E   R+NK L+ 
Sbjct: 1457 LAEEKSISARYAEERDRAEAEAREKETKALS-----LARALEEALEAKEEFERQNKQLRA 1511

Query: 1511 EISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQ 1570
            ++ DL     + GK +HELEK K+ +EQ+  E++  LEE E  L+  E   LR+++ +  
Sbjct: 1512 DMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQA 1571

Query: 1571 VKSEVDRKIAEKDEEIDQLKRNHTRVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEMEI 1630
            +K++ +R +  +DE+ ++ KR   + V  +++ L+ E + R  A+  KKKME DL ++E 
Sbjct: 1572 MKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEA 1631

Query: 1631 QLNHANRLAAESLRNYRNTQGILKETQLHLDDALRGQEDLKEQLAIVERRANLLQAEIEE 1690
            Q+  AN+   E ++  R  Q  +K+ Q  L++A   ++++  Q    E++   L+AEI +
Sbjct: 1632 QIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQ 1691

Query: 1691 LWATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQE 1750
            L   L  +ER+R+ AEQE  + ++ +    +  ++L++ K++LE  ++QL+ E+EE    
Sbjct: 1692 LQEELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSN 1751

Query: 1751 SRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKG 1810
                 ++ +K       +  EL  E+  +   +  ++ LE+  K+L+ +L E E      
Sbjct: 1752 MELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSK 1811

Query: 1811 GKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNVLRLQDL 1870
             K  I  LEA++ +LE ++E E K  A A K +R+ E+++KE+  Q E++R++  + ++ 
Sbjct: 1812 FKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQ 1871

Query: 1871 VDKLQAKVKSYKRQAEEAEEQSNANLSKFRKLQHELEEAEERADIAESQVNKLRVKSR 1928
            ++K  A++K  KRQ EEAEE++    +  RKLQ EL++A E  +    +V+ L+ + R
Sbjct: 1872 MEKANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEANEGLSREVSTLKNRLR 1929



 Score =  250 bits (639), Expect = 8e-66
 Identities = 216/986 (21%), Positives = 452/986 (45%), Gaps = 109/986 (11%)

Query: 847  ETEKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTL-------LKEKNDLQLQVQSEAD 899
            + E+++   +   QK + E   +EAK K++EE+++ L       +KEK  ++ ++   + 
Sbjct: 954  DLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSS 1013

Query: 900  SLADAEERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLE-------DECSE 952
             LA+ EE+ + L K + + E  I ++ ER ++EE+   EL   KRKL+       D+ +E
Sbjct: 1014 QLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAE 1073

Query: 953  LKKDIDDLELTLAKVEKE--------------KHATENKVKNLTEEMAGLDETIA----- 993
            L+  ID+L+L LAK E+E              K+     V+ L  ++A L E        
Sbjct: 1074 LQAQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKAS 1133

Query: 994  --KLSKEKKALQETHQQTLDDLQAEEDKVNILTKAKTKLEQQVDDLEGSLEQE------- 1044
              K  K+K+ L E  +    +L+   D      + +TK EQ+V +L+ +LE+E       
Sbjct: 1134 RNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQ 1193

Query: 1045 ----------------------KKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQLDEK 1082
                                  K+ + +LE+ K+ LE D K        ++  K + + K
Sbjct: 1194 IQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHK 1253

Query: 1083 LEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQRSDL 1142
             +K + ++  L +K+ +   + ++L +K  +LQ  ++ +   +E       K  K  + L
Sbjct: 1254 RKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASL 1313

Query: 1143 SRELEEISERLEEAGGAT---SAQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRKKH 1199
              +L++  E L+E        S+++   ++ +   Q+ + + EEA    E  V AL+ + 
Sbjct: 1314 ESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQL 1373

Query: 1200 ADSMAELGEQIDNLQRVKQ------------------------KLEKEKSELKMETDDLS 1235
            AD+  ++ + +  ++ +++                        KLEK K+ L+ E DDL+
Sbjct: 1374 ADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLT 1433

Query: 1236 SNAEAISKAKGNLEKMCRSLEDQVSELKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLD 1295
             + +   +   NLEK  +  +  ++E K+         +   A+    +T+A   +R L+
Sbjct: 1434 VDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALE 1493

Query: 1296 EKDALVSQLSRSKQASTQQIEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEEEQE 1355
            E      +  R  +     +E+L    ++  K  + L  + ++     + +R Q EE ++
Sbjct: 1494 EALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELED 1553

Query: 1356 GKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCA 1415
                 + A  +    +   + ++E D   R E+ EE K+ L ++++E E  +E    + A
Sbjct: 1554 ELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRA 1613

Query: 1416 SLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQA---ELEA 1472
                +K++++ +++DL   +E +N A   + K+ R     + +++++ EE +A   E+ A
Sbjct: 1614 LAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFA 1673

Query: 1473 SQKES----RSLSTELFKVKNVYEESLDQLETLRRENKNLQQEISDLTEQIAEGGKQIHE 1528
              KES    +SL  E+ +++       ++L +  R  ++ +QE  +L ++I         
Sbjct: 1674 QSKESEKKLKSLEAEILQLQ-------EELASSERARRHAEQERDELADEITNSASGKSA 1726

Query: 1529 LEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEV--DRKIAEKDEEI 1586
            L   K+++E    +++  LEE ++++E    +  +  L+++ + +E+  +R  A+K +  
Sbjct: 1727 LLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNA 1786

Query: 1587 DQLKRNHTRVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEMEIQLNHANRLAAESLRNY 1646
             Q      + ++     L+  ++S+  A      +E  + ++E QL    +  A + +  
Sbjct: 1787 RQQLERQNKELKAKLQELEGAVKSKFKA--TISALEAKIGQLEEQLEQEAKERAAANKLV 1844

Query: 1647 RNTQGILKETQLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELWATLEQTERSRKIAE 1706
            R T+  LKE  + ++D  R  +  KEQ+     R   L+ ++EE      +   SR+  +
Sbjct: 1845 RRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQ 1904

Query: 1707 QELLDASERVQLLHTQNTSLINTKKK 1732
            +EL DA+E  + L  + ++L N  ++
Sbjct: 1905 RELDDATEANEGLSREVSTLKNRLRR 1930



 Score =  186 bits (471), Expect = 2e-46
 Identities = 183/877 (20%), Positives = 399/877 (45%), Gaps = 82/877 (9%)

Query: 1105 IQLQKKIKELQARIEELGEEIEAERASRAKAEKQRSDLSRELEEIS---ERLEEAGGATS 1161
            +Q+ ++ +ELQA+ EEL            K +++++ +  ELEE+    ++L E     +
Sbjct: 845  LQVTRQEEELQAKDEEL-----------LKVKEKQTKVEGELEEMERKHQQLLEEKNILA 893

Query: 1162 AQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRKKHADSMAELGEQIDNLQRVKQKLE 1221
             Q++   +  AE +++R           A +AA +++  + + +L  +++  +   Q L+
Sbjct: 894  EQLQAETELFAEAEEMR-----------ARLAAKKQELEEILHDLESRVEEEEERNQILQ 942

Query: 1222 KEKSELKMETDDLSSNAEAISKAKGNLEKMCRSLEDQVSELKTKEEEQQRLI-----NDL 1276
             EK +++    DL    E + + +G  +K+   LE   +E K K+ E++ L+     +  
Sbjct: 943  NEKKKMQAHIQDLE---EQLDEEEGARQKL--QLEKVTAEAKIKKMEEEILLLEDQNSKF 997

Query: 1277 TAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKHQLEEETKAKNALAHAL 1336
              ++  ++    E S QL E++     L++ +      I +L+ +L++E K +  L  A 
Sbjct: 998  IKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAK 1057

Query: 1337 QSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKL 1396
            +    +   L++Q  E Q    EL+  L+K   E+     + + + + +   L+  ++  
Sbjct: 1058 RKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQ 1117

Query: 1397 AQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVL 1456
            AQ + E +E  E+  A     EK K+ L  E+E L  ++E +    AA  + +   ++ +
Sbjct: 1118 AQ-IAELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEV 1176

Query: 1457 SEWKQKYEETQAELEASQKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEISDLT 1516
            +E K+  EE     EA  ++ R       +     EE  +QLE  +R   NL++    L 
Sbjct: 1177 AELKKALEEETKNHEAQIQDMRQ------RHATALEELSEQLEQAKRFKANLEKNKQGLE 1230

Query: 1517 EQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQL--ELNQVKSE 1574
                E   ++  L+++K + E ++ ++ A ++E  A +   EG  LR++L  + +++++E
Sbjct: 1231 TDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVS--EGDRLRVELAEKASKLQNE 1288

Query: 1575 VDRKIAEKDEEIDQLKRNHTRVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEMEIQLNH 1634
            +D  ++   EE ++      +   +++S L        +  R K  +   + ++E + N 
Sbjct: 1289 LDN-VSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNS 1347

Query: 1635 ANRLAAESLRNYRNT-------QGILKETQLHLDDALRGQEDLKEQLAIVERRANLLQAE 1687
                  E     +N        Q  L +T+  +DD L   E L+E    + + A  L   
Sbjct: 1348 LQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQR 1407

Query: 1688 IEELWATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEV 1747
            +EE     ++ E+++   +QEL D +  +       ++L   +KK +  +++ +S     
Sbjct: 1408 LEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARY 1467

Query: 1748 IQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAE--- 1804
             +E   AE +A++  T A  +A  L++  +     ER  K L   ++DL    D+     
Sbjct: 1468 AEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNV 1527

Query: 1805 ---QLALKGGKKQIQKLEARVRELEGEVE-----------NEQKRNAEAVKGLRKHE--- 1847
               + + +  ++Q++++  ++ ELE E++           N Q   A+  + L+  +   
Sbjct: 1528 HELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQN 1587

Query: 1848 --------RRVKELTYQTEEDRKNVLRLQDLVDKLQAKVKSYKRQAEEAEEQSNANLSKF 1899
                    ++V+EL  + E++RK          K++  +K  + Q E A +  +  + + 
Sbjct: 1588 EEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQL 1647

Query: 1900 RKLQHELEEAEERADIAESQVNKLRVKSREVHTKISA 1936
            RKLQ ++++ +   + A +  +++  +S+E   K+ +
Sbjct: 1648 RKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKS 1684



 Score =  177 bits (450), Expect = 7e-44
 Identities = 159/741 (21%), Positives = 351/741 (47%), Gaps = 50/741 (6%)

Query: 850  KEMATMKEEFQKTKDELAKSEAKRKELEEKM--------------VTLLKEKNDLQLQVQ 895
            KE+A   +  Q+ K   A+SE KRK+L+ ++              V L ++ + LQ ++ 
Sbjct: 1234 KELACEVKVLQQVK---AESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELD 1290

Query: 896  SEADSLADAEERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKK 955
            + +  L +AE++  +  K+   LE+++++  E  +EE      L+++ R+LE+E + L++
Sbjct: 1291 NVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQE 1350

Query: 956  DIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQA 1015
              ++ E     +EK+  A ++++ +  +++     TI  L + KK L +  +     L+ 
Sbjct: 1351 QQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEE 1410

Query: 1016 EEDKVNILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDME-- 1073
            +    + L K K +L+Q++DDL   L+ ++++  +LE+ ++K   D  LA+E ++     
Sbjct: 1411 KALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKF--DQLLAEEKSISARYA 1468

Query: 1074 NDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEEL-------GEEIE 1126
             ++ + + +  +KE +  +L   +E+    + + +++ K+L+A +E+L       G+ + 
Sbjct: 1469 EERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVH 1528

Query: 1127 AERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATL 1186
                S+   E+Q  ++  +LEE+ + L+       A++ L    +A   +  RDL+    
Sbjct: 1529 ELEKSKRALEQQVEEMRTQLEELEDELQ---ATEDAKLRLEVNMQAMKAQFERDLQTRDE 1585

Query: 1187 QHEAMVAALRKKHADSMAELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKG 1246
            Q+E     L K+  +  AEL ++    QR      K+K E+ ++  DL +  EA +KA+ 
Sbjct: 1586 QNEEKKRLLIKQVRELEAELEDE--RKQRALAVASKKKMEIDLK--DLEAQIEAANKARD 1641

Query: 1247 NLEKMCRSLEDQVSELKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQLSR 1306
             + K  R L+ Q+ + + + EE +   +++ AQ    + +      ++ +    ++   R
Sbjct: 1642 EVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSER 1701

Query: 1307 SKQASTQQIEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSK 1366
            +++ + Q+ +EL  ++      K+AL    +        L E+ EEEQ     L     K
Sbjct: 1702 ARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRK 1761

Query: 1367 ANSEVAQWRTKY--ETDAIQRTE----ELEEAKKKLAQRLQEAEEHVEA-VNAKCASLEK 1419
               +V     +   E  A Q+++    +LE   K+L  +LQE E  V++   A  ++LE 
Sbjct: 1762 TTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSKFKATISALEA 1821

Query: 1420 TKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQAELEASQKESRS 1479
               +L+ ++E    +   +N      +KK +     + + ++  ++ + ++E +    + 
Sbjct: 1822 KIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQ 1881

Query: 1480 LSTELFKVKNVYEESLDQLETLRRE-------NKNLQQEISDLTEQIAEGGK-QIHELEK 1531
            L  +L + +     +      L+RE       N+ L +E+S L  ++  GG         
Sbjct: 1882 LKRQLEEAEEEATRANASRRKLQRELDDATEANEGLSREVSTLKNRLRRGGPISFSSSRS 1941

Query: 1532 IKKQVEQEKCEIQAALEEAEA 1552
             ++Q+  E   ++ + ++ E+
Sbjct: 1942 GRRQLHLEGASLELSDDDTES 1962



 Score = 79.0 bits (193), Expect = 4e-14
 Identities = 76/323 (23%), Positives = 146/323 (45%), Gaps = 14/323 (4%)

Query: 1616 RVKKKMEGDLNEMEIQLNHANRLAAESLRNYRNTQGILKETQLHLDDALRGQEDLKEQLA 1675
            +VK  ++    E E+Q      L  +  +     +G L+E +      L  +  L EQL 
Sbjct: 840  KVKPLLQVTRQEEELQAKDEELLKVKEKQT--KVEGELEEMERKHQQLLEEKNILAEQL- 896

Query: 1676 IVERRANLLQAEIEELWATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLEN 1735
               +    L AE EE+ A L   ++     E+ L D   RV+    +N  L N KKK++ 
Sbjct: 897  ---QAETELFAEAEEMRARLAAKKQE---LEEILHDLESRVEEEEERNQILQNEKKKMQA 950

Query: 1736 DVSQLQSEVEEVIQESRNAEEKAKKAITDAAM--MAEELKKEQDTSAHLERMKKNLEQTV 1793
             +  L+ +++E  +E    + + +K   +A +  M EE+   +D ++   + KK +E  +
Sbjct: 951  HIQDLEEQLDE--EEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRI 1008

Query: 1794 KDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHERRVKEL 1853
             +   +L E E+ A K   K   K E  + +LE  ++ E+K   E  K  RK +    +L
Sbjct: 1009 AECSSQLAEEEEKA-KNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDL 1067

Query: 1854 TYQTEEDRKNVLRLQDLVDKLQAKVKSYKRQAEEAEEQSNANLSKFRKLQHELEEAEERA 1913
              Q  E +  +  L+  + K + +++    + ++     N  L   R+LQ ++ E +E  
Sbjct: 1068 QDQIAELQAQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDF 1127

Query: 1914 DIAESQVNKLRVKSREVHTKISA 1936
            +  ++  NK   + R++  ++ A
Sbjct: 1128 ESEKASRNKAEKQKRDLSEELEA 1150



 Score = 40.0 bits (92), Expect = 0.022
 Identities = 32/129 (24%), Positives = 65/129 (50%), Gaps = 19/129 (14%)

Query: 1813 KQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVD 1872
            +Q ++L+A+  EL    E + K   E  +  RKH++ ++E         KN+L      +
Sbjct: 849  RQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEE---------KNIL-----AE 894

Query: 1873 KLQAKVKSYKRQAEEAEEQSNANLSKFRKLQHELE----EAEERADIAESQVNKLRVKSR 1928
            +LQA+ + +  +AEE   +  A   +  ++ H+LE    E EER  I +++  K++   +
Sbjct: 895  QLQAETELFA-EAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQ 953

Query: 1929 EVHTKISAE 1937
            ++  ++  E
Sbjct: 954  DLEEQLDEE 962


>gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens]
          Length = 1995

 Score = 1300 bits (3364), Expect = 0.0
 Identities = 721/1873 (38%), Positives = 1125/1873 (60%), Gaps = 21/1873 (1%)

Query: 67   EGGATLTVREDQVFPMNPPKYDKIEDMAMMTHLHEPGVLYNLKERYAAWMIYTYSGLFCV 126
            E G  L +  DQ+  MNPPK+ K EDMA +T L+E  VL+NL+ERY + +IYTYSGLFCV
Sbjct: 84   ESGRRLRLPRDQIQRMNPPKFSKAEDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCV 143

Query: 127  TVNPYKWLPVYKPEVVAAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAG 186
             +NPYK LP+Y   +V  YRGKKR E PPH++++++ AY+ ML DRE+QSIL TGESGAG
Sbjct: 144  VINPYKQLPIYTEAIVEMYRGKKRHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAG 203

Query: 187  KTVNTKRVIQYFATIAVTGEKKKDESGKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSR 246
            KT NTK+VIQY A +A + + +K+    + G LE Q++ ANP+LEAFGNAKTV+NDNSSR
Sbjct: 204  KTENTKKVIQYLAHVASSPKGRKEPG--VPGELERQLLQANPILEAFGNAKTVKNDNSSR 261

Query: 247  FGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQITSNKKPDLIEMLLI 306
            FGKFIRI+F   G +  A+IETYLLEKSR   Q K E S+HIFYQ+       L   LL+
Sbjct: 262  FGKFIRINFDVAGYIVGANIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLL 321

Query: 307  TTNPYDYAFVSQGEITVPSIDDQEELMATDSAIDILGFTPEEKVSIYKLTGAVMHYGNMK 366
                + Y F++ G  + P   ++E    T  ++ +LGF+ EE +S+ ++  AV+ +GN+ 
Sbjct: 322  EPCSH-YRFLTNGPSSSPG-QERELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIA 379

Query: 367  FKQKQREEQAEPDGTEVADKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTVQQVYNA 426
             K+++  +QA       A K   L  L   D  +AL  PR+KVG +YV K QT +Q   A
Sbjct: 380  LKRERNTDQATMPDNTAAQKLCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFA 439

Query: 427  VGALAKAVYEKMFLWMVTRINQQLDTKQPRQ--YFIGVLDIAGFEIFDFNSLEQLCINFT 484
            + ALAKA YE++F W+V R+N+ LD + PRQ   F+G+LDIAGFEIF  NS EQLCIN+T
Sbjct: 440  LEALAKATYERLFRWLVLRLNRALD-RSPRQGASFLGILDIAGFEIFQLNSFEQLCINYT 498

Query: 485  NEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPL---GIFSILEEEC 541
            NEKLQQ FNH MFVLEQEEY++EGI WTF+DFG+DL  CI+LIE+P    G+ ++L+EEC
Sbjct: 499  NEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEEC 558

Query: 542  MFPKATDTSFKNKLYDQHLGKSANFQKPKVVKGKAEAHFSLIHYAGTVDYNITGWLDKNK 601
             FPKATD SF  K+  Q  G    FQ+P+ ++ +A+  FS++HYAG VDY    WL KN 
Sbjct: 559  WFPKATDKSFVEKVA-QEQGGHPKFQRPRHLRDQAD--FSVLHYAGKVDYKANEWLMKNM 615

Query: 602  DPLNDTVVGLYQKSAMKTLASLFSTY---ASAEADSS---AKKGAKKKGSSFQTVSALFR 655
            DPLND V  L  +S  +  A ++         E  SS      G + +   F+TV  L++
Sbjct: 616  DPLNDNVAALLHQSTDRLTAEIWKDVEGIVGLEQVSSLGDGPPGGRPRRGMFRTVGQLYK 675

Query: 656  ENLNKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSR 715
            E+L++LM  L +T+P FVRCI+PN  K  G +E  LVL QLRCNGVLEGIRICR+GFP+R
Sbjct: 676  ESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNR 735

Query: 716  ILYGDFKQRYKVLNASAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGL 775
            IL+ +F+QRY++L  +AIP+G F+D K+A EK++ ++++D   Y+ G +K+FF+AG+L  
Sbjct: 736  ILFQEFRQRYEILTPNAIPKG-FMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQ 794

Query: 776  LEEMRDEKLAQIITRTQAVCRGFLMRVEYQKMLQRREALFCIQYNVRAFMNVKHWPWMKL 835
            LEE RD K+  II   QA  RG+L R  +QK  Q++ AL  +Q N  A++ ++HW W +L
Sbjct: 795  LEEERDLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRL 854

Query: 836  FFKIKPLLKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQ 895
            F K+KPLL+    ++ +    +E QK ++   +S  +  EL+ ++  L +E+  L  Q++
Sbjct: 855  FTKVKPLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLR 914

Query: 896  SEADSLADAEERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKK 955
            +EA+  A+AEE   +L   K +LE  + E+  R  EEEE + ++  +K++L+    EL+ 
Sbjct: 915  AEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEA 974

Query: 956  DIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQA 1015
             ++  E    K++ EK  TE K+K   E++  L++  +KLSKE+K L++   +       
Sbjct: 975  HLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAE 1034

Query: 1016 EEDKVNILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMEND 1075
            EE+KV  L K + K E  + D+E  L +E+K R +LE+ KR+L+G+    QE  ++ +  
Sbjct: 1035 EEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQR 1094

Query: 1076 KQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKA 1135
             ++L  +L +KE E+   +++ EDE     QL K ++E QA + E  E++E+ER +R KA
Sbjct: 1095 AEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKA 1154

Query: 1136 EKQRSDLSRELEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAAL 1195
            EKQR DL  ELE +   LE+   +T+AQ EL  KRE E  +L++ LEE T  HEA V  L
Sbjct: 1155 EKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQEL 1214

Query: 1196 RKKHADSMAELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGNLEKMCRSL 1255
            R++H  ++ EL EQ++  +R K   EK +  L+ E  +L +   ++  A+   E+  R L
Sbjct: 1215 RQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRL 1274

Query: 1256 EDQVSELKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQI 1315
            E Q+ E++ +  + +R   +   +  R Q E    S  L+E ++   +LS+   ++  Q+
Sbjct: 1275 ELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQL 1334

Query: 1316 EELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWR 1375
             + +  L+EET+AK AL   +++   +   LREQ EEE   +    R L  A +++++WR
Sbjct: 1335 HDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWR 1394

Query: 1376 TKYETDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDV 1435
             + E +A    E  EEA+++ A+  +   + +         LE+ ++RLQ E++D  +D+
Sbjct: 1395 RRQEEEA-GALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDL 1453

Query: 1436 ERSNAACAALDKKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELFKVKNVYEESL 1495
            E+     + L+KKQR FD++L+E K        E E ++ E R        +    EE  
Sbjct: 1454 EQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQ 1513

Query: 1496 DQLETLRRENKNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLE 1555
            +  E L R+N+ L+ E+  L     + GK +HELE+  +  EQ   +++A + E E  L 
Sbjct: 1514 EAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELT 1573

Query: 1556 HEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHTRVVETMQSTLDAEIRSRNDAL 1615
              E   LR+++ +  +K++ +R +  +DE  ++ +R   + +   +   D E + R  A+
Sbjct: 1574 AAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAV 1633

Query: 1616 RVKKKMEGDLNEMEIQLNHANRLAAESLRNYRNTQGILKETQLHLDDALRGQEDLKEQLA 1675
              +KK+EG+L E++ Q+  A +   E+++  R  Q  +KE    +++    +E++  Q  
Sbjct: 1634 AARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNR 1693

Query: 1676 IVERRANLLQAEIEELWATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLEN 1735
              E+R   L+AE+  L   L  ++R+R+ A+Q+  + ++ V   +    +++  K++LE 
Sbjct: 1694 ESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEG 1753

Query: 1736 DVSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKD 1795
             + QL+ E+EE    S    ++ +K +     +  EL  E+  SA  E  ++ LE+ +++
Sbjct: 1754 RLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQE 1813

Query: 1796 LQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHERRVKELTY 1855
            L+ RL E +  A    K  I  LE+++ + E ++E E +    + K +R+ E+R+KE+  
Sbjct: 1814 LRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVL 1873

Query: 1856 QTEEDRKNVLRLQDLVDKLQAKVKSYKRQAEEAEEQSNANLSKFRKLQHELEEAEERADI 1915
            Q EE+R+   +L+D ++K   +VK  KRQ EEAEE+++   +  R+LQ ELE+  E A+ 
Sbjct: 1874 QVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAES 1933

Query: 1916 AESQVNKLRVKSR 1928
               +V  LR + R
Sbjct: 1934 MNREVTTLRNRLR 1946



 Score =  227 bits (579), Expect = 7e-59
 Identities = 234/997 (23%), Positives = 455/997 (45%), Gaps = 114/997 (11%)

Query: 996  SKEKKALQETHQQTLDDLQAEEDKVNILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAK 1055
            +K K  LQ T Q  +  LQA   ++  + + + +  ++V +L+G + Q       LE  +
Sbjct: 856  TKVKPLLQVTRQDEV--LQARAQELQKVQELQQQSAREVGELQGRVAQ-------LEEER 906

Query: 1056 RKLEGDLKLAQESTMDMENDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQ 1115
             +L   L+   E   + E  + +L  + ++ E  +S L +++ +E+    Q+Q + K LQ
Sbjct: 907  ARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQ 966

Query: 1116 ARIEELGEEIEAERASRAKAEKQRSDLSRELEEISERL---EEAGGATSAQVELNKKREA 1172
              I+EL   +EAE  +R K + ++     ++++  E L   E+     S + +L + R A
Sbjct: 967  QHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLA 1026

Query: 1173 EFQKLRRDLEEATLQHEAMVAALRKKHADSMAELGEQIDNLQRVKQKLEKEKSELKMETD 1232
            EF     + EE        +  LR K+  ++A++          + +L KE+        
Sbjct: 1027 EFSSQAAEEEEKVKS----LNKLRLKYEATIADM----------EDRLRKEE-------- 1064

Query: 1233 DLSSNAEAISKAKGNLEKMCRSLEDQVSELKTKEEEQQRLINDLTAQRARLQTEAGEYSR 1292
                      K +  LEK+ R L+ + SEL+ +  EQQ+   +L AQ  R + E      
Sbjct: 1065 ----------KGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALA 1114

Query: 1293 QLDEKDALVSQLSRSKQASTQQIEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEE 1352
            + +++    +QL +S + +   + E +  LE E  A+       +    + + LR + E+
Sbjct: 1115 RAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELED 1174

Query: 1353 EQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNA 1412
              +     Q   SK   EV + +   E +       ++E +++  Q L E  E +E    
Sbjct: 1175 TLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARR 1234

Query: 1413 KCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQ-AELE 1471
               + EKT+  L+ EV +L  ++     A    ++++R  +  L E + +  + + A  E
Sbjct: 1235 GKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAE 1294

Query: 1472 ASQKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEISDLTEQIAEGGKQIHELEK 1531
            A++K  R+   EL  V     E+  +   L +E  + + ++ D  E + E  +    L  
Sbjct: 1295 AAEKLQRA-QAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGS 1353

Query: 1532 IKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEVD--------------- 1576
              + +E E   ++  LEE  A+ E    ++   Q +L++ +   +               
Sbjct: 1354 RVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRR 1413

Query: 1577 ---------RKIAEKDEEIDQLKRNHTRVVETMQ-STLDAEIRSRNDALRVKKKMEGDLN 1626
                     +++AEK E +D+L+R   R+ + +  +T+D E + +  +   KK+ + D  
Sbjct: 1414 AAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQL 1473

Query: 1627 EMEIQLNHANRLAAESLRNYRNTQGILKETQ-LHLDDALRGQEDLKEQLAIVERRANLLQ 1685
              E     A  L A   R     +G  +E + L L  AL  +++ +E+L   ER+   L+
Sbjct: 1474 LAE---EKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREEL---ERQNRALR 1527

Query: 1686 AEIEELWAT-------LEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVS 1738
            AE+E L ++       + + ER+ ++AEQ   D   +V  L  + T+  + K +LE  V 
Sbjct: 1528 AELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQ 1587

Query: 1739 QLQSEVEEVIQESRNAEEKAK----KAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVK 1794
             L+++ E  +Q    A E+ +    K + DA +  +E +K++  +      +K LE  ++
Sbjct: 1588 ALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAV---AARKKLEGELE 1644

Query: 1795 DLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHERRVKELT 1854
            +L+ ++  A Q   +   KQ++K++A+++EL  EVE  +    E     R+ E+R+K L 
Sbjct: 1645 ELKAQMASAGQ-GKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLE 1703

Query: 1855 YQTEEDRKNVLRLQD-LVDKLQAKVKSYKRQAEEAEEQSNANLSK-------------FR 1900
             +       VLRLQ+ L    +A+ ++ + + E A+E +N NLSK               
Sbjct: 1704 AE-------VLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLG 1756

Query: 1901 KLQHELEEAEERADIAESQVNKLRVKSREVHTKISAE 1937
            +L+ ELEE +  +++   +  KL ++   + T++SAE
Sbjct: 1757 QLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAE 1793



 Score =  219 bits (557), Expect = 3e-56
 Identities = 205/953 (21%), Positives = 425/953 (44%), Gaps = 43/953 (4%)

Query: 838  KIKPL----LKSAETEKEMATMKEEFQKTKDELAKS----EAKRKELEEKMVTLLKEKND 889
            K+K L    LK   T  +M     + +K + EL K     + +  EL+E+MV   +   +
Sbjct: 1038 KVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEE 1097

Query: 890  LQLQVQSEADSLADAEERCE-------QLIKNKIQLEAKIKEVTERAEEEEEINAELTAK 942
            L+ Q+  + + L  A  R E       QL+K+  + +A + E  E  E E     +   +
Sbjct: 1098 LRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQ 1157

Query: 943  KRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKAL 1002
            +R L +E   L+ +++D   TL     ++     + + +TE    L+E         + L
Sbjct: 1158 RRDLGEELEALRGELED---TLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQEL 1214

Query: 1003 QETHQQTLDDLQAEEDKVN----ILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKL 1058
            ++ H Q L +L  + ++         K +  LE +V +L   L   +  R + E+ +R+L
Sbjct: 1215 RQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRL 1274

Query: 1059 EGDLKLAQESTMDMENDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARI 1118
            E  L+  Q    D E  + +  EKL++ + E+ N+   + + ++  I+L K++   +A++
Sbjct: 1275 ELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQL 1334

Query: 1119 EELGEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQVELNKKREAEFQKLR 1178
             +  E ++ E  ++     +   +  E   + E+LEE   A        +  +A+  + R
Sbjct: 1335 HDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWR 1394

Query: 1179 RDLEEATLQHEAMVAALRKKHADS------MAELGEQIDNLQRVKQKLEKEKSELKMETD 1232
            R  EE     EA   A R+   ++      +AE  E +D L+R +++L++E  +  M   
Sbjct: 1395 RRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATM--- 1451

Query: 1233 DLSSNAEAISKAKGNLEKMCRSLEDQVSELKTKEEEQQRLINDLTAQRARLQTEAGEYSR 1292
            DL    + +S  +    K  + L ++ + +    EE++R      A+    +  A   +R
Sbjct: 1452 DLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERA----EAEGREREARALSLTR 1507

Query: 1293 QLDEKDALVSQLSRSKQASTQQIEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEE 1352
             L+E+     +L R  +A   ++E L    ++  K+ + L  A + +    + LR Q  E
Sbjct: 1508 ALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTE 1567

Query: 1353 EQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNA 1412
             ++     + A  +    V   +T++E D   R E  EE +++LA++L++AE   +    
Sbjct: 1568 LEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERK 1627

Query: 1413 KCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQAELEA 1472
            +       +++L+ E+E+L   +  +        K+ R     + E  ++ EET+   E 
Sbjct: 1628 QRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREE 1687

Query: 1473 SQKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEISDLTEQIAEGGKQIHELEKI 1532
               ++R     L  ++       ++L    R  +  QQ+  ++ +++A G      + + 
Sbjct: 1688 IFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEE 1747

Query: 1533 KKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEV--DRKIAEKDEEIDQLK 1590
            K+Q+E    +++  LEE +++ E    +  ++ L++  + +E+  +R  + K E   Q  
Sbjct: 1748 KRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQL 1807

Query: 1591 RNHTRVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEMEIQLNHANRLAAESLRNYRNTQ 1650
                + +       DA  R+R+        +E  L + E QL    R    S +  R  +
Sbjct: 1808 ERQIQELRGRLGEEDAGARARHKMTIAA--LESKLAQAEEQLEQETRERILSGKLVRRAE 1865

Query: 1651 GILKETQLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELWATLEQTERSRKIAEQELL 1710
              LKE  L +++  R  + L++QL     R   L+ ++EE      + +  R+  ++EL 
Sbjct: 1866 KRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELE 1925

Query: 1711 DASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEV--IQESRNAEEKAKKA 1761
            D +E  + ++ + T+L N  ++    ++     V +V  ++E   ++E+A++A
Sbjct: 1926 DVTESAESMNREVTTLRNRLRR--GPLTFTTRTVRQVFRLEEGVASDEEAEEA 1976


>gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens]
          Length = 2003

 Score = 1298 bits (3358), Expect = 0.0
 Identities = 722/1879 (38%), Positives = 1125/1879 (59%), Gaps = 25/1879 (1%)

Query: 67   EGGATLTVREDQVFPMNPPKYDKIEDMAMMTHLHEPGVLYNLKERYAAWMIYTYSGLFCV 126
            E G  L +  DQ+  MNPPK+ K EDMA +T L+E  VL+NL+ERY + +IYTYSGLFCV
Sbjct: 84   ESGRRLRLPRDQIQRMNPPKFSKAEDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCV 143

Query: 127  TVNPYKWLPVYKPEVVAAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAG 186
             +NPYK LP+Y   +V  YRGKKR E PPH++++++ AY+ ML DRE+QSIL TGESGAG
Sbjct: 144  VINPYKQLPIYTEAIVEMYRGKKRHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAG 203

Query: 187  KTVNTKRVIQYFATIAVTGEKKKDE------SGKMQGTLEDQIISANPLLEAFGNAKTVR 240
            KT NTK+VIQY A +A + + +K+       S    G LE Q++ ANP+LEAFGNAKTV+
Sbjct: 204  KTENTKKVIQYLAHVASSPKGRKEPGVPASVSTVSYGELERQLLQANPILEAFGNAKTVK 263

Query: 241  NDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQITSNKKPDL 300
            NDNSSRFGKFIRI+F   G +  A+IETYLLEKSR   Q K E S+HIFYQ+       L
Sbjct: 264  NDNSSRFGKFIRINFDVAGYIVGANIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQL 323

Query: 301  IEMLLITTNPYDYAFVSQGEITVPSIDDQEELMATDSAIDILGFTPEEKVSIYKLTGAVM 360
               LL+    + Y F++ G  + P   ++E    T  ++ +LGF+ EE +S+ ++  AV+
Sbjct: 324  KADLLLEPCSH-YRFLTNGPSSSPG-QERELFQETLESLRVLGFSHEEIISMLRMVSAVL 381

Query: 361  HYGNMKFKQKQREEQAEPDGTEVADKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTV 420
             +GN+  K+++  +QA       A K   L  L   D  +AL  PR+KVG +YV K QT 
Sbjct: 382  QFGNIALKRERNTDQATMPDNTAAQKLCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTK 441

Query: 421  QQVYNAVGALAKAVYEKMFLWMVTRINQQLDTKQPRQ--YFIGVLDIAGFEIFDFNSLEQ 478
            +Q   A+ ALAKA YE++F W+V R+N+ LD + PRQ   F+G+LDIAGFEIF  NS EQ
Sbjct: 442  EQADFALEALAKATYERLFRWLVLRLNRALD-RSPRQGASFLGILDIAGFEIFQLNSFEQ 500

Query: 479  LCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPL---GIFS 535
            LCIN+TNEKLQQ FNH MFVLEQEEY++EGI WTF+DFG+DL  CI+LIE+P    G+ +
Sbjct: 501  LCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGLDLQPCIDLIERPANPPGLLA 560

Query: 536  ILEEECMFPKATDTSFKNKLYDQHLGKSANFQKPKVVKGKAEAHFSLIHYAGTVDYNITG 595
            +L+EEC FPKATD SF  K+  Q  G    FQ+P+ ++ +A+  FS++HYAG VDY    
Sbjct: 561  LLDEECWFPKATDKSFVEKVA-QEQGGHPKFQRPRHLRDQAD--FSVLHYAGKVDYKANE 617

Query: 596  WLDKNKDPLNDTVVGLYQKSAMKTLASLFSTY---ASAEADSS---AKKGAKKKGSSFQT 649
            WL KN DPLND V  L  +S  +  A ++         E  SS      G + +   F+T
Sbjct: 618  WLMKNMDPLNDNVAALLHQSTDRLTAEIWKDVEGIVGLEQVSSLGDGPPGGRPRRGMFRT 677

Query: 650  VSALFRENLNKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICR 709
            V  L++E+L++LM  L +T+P FVRCI+PN  K  G +E  LVL QLRCNGVLEGIRICR
Sbjct: 678  VGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICR 737

Query: 710  KGFPSRILYGDFKQRYKVLNASAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFK 769
            +GFP+RIL+ +F+QRY++L  +AIP+G F+D K+A EK++ ++++D   Y+ G +K+FF+
Sbjct: 738  QGFPNRILFQEFRQRYEILTPNAIPKG-FMDGKQACEKMIQALELDPNLYRVGQSKIFFR 796

Query: 770  AGLLGLLEEMRDEKLAQIITRTQAVCRGFLMRVEYQKMLQRREALFCIQYNVRAFMNVKH 829
            AG+L  LEE RD K+  II   QA  RG+L R  +QK  Q++ AL  +Q N  A++ ++H
Sbjct: 797  AGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAAYLKLRH 856

Query: 830  WPWMKLFFKIKPLLKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKND 889
            W W +LF K+KPLL+    ++ +    +E QK ++   +S  +  EL+ ++  L +E+  
Sbjct: 857  WQWWRLFTKVKPLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEERAR 916

Query: 890  LQLQVQSEADSLADAEERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDE 949
            L  Q+++EA+  A+AEE   +L   K +LE  + E+  R  EEEE + ++  +K++L+  
Sbjct: 917  LAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQH 976

Query: 950  CSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQT 1009
              EL+  ++  E    K++ EK  TE K+K   E++  L++  +KLSKE+K L++   + 
Sbjct: 977  IQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEF 1036

Query: 1010 LDDLQAEEDKVNILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQEST 1069
                  EE+KV  L K + K E  + D+E  L +E+K R +LE+ KR+L+G+    QE  
Sbjct: 1037 SSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQM 1096

Query: 1070 MDMENDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAER 1129
            ++ +   ++L  +L +KE E+   +++ EDE     QL K ++E QA + E  E++E+ER
Sbjct: 1097 VEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESER 1156

Query: 1130 ASRAKAEKQRSDLSRELEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQHE 1189
             +R KAEKQR DL  ELE +   LE+   +T+AQ EL  KRE E  +L++ LEE T  HE
Sbjct: 1157 VARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHE 1216

Query: 1190 AMVAALRKKHADSMAELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGNLE 1249
            A V  LR++H  ++ EL EQ++  +R K   EK +  L+ E  +L +   ++  A+   E
Sbjct: 1217 AAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGE 1276

Query: 1250 KMCRSLEDQVSELKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQ 1309
            +  R LE Q+ E++ +  + +R   +   +  R Q E    S  L+E ++   +LS+   
Sbjct: 1277 QRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELS 1336

Query: 1310 ASTQQIEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANS 1369
            ++  Q+ + +  L+EET+AK AL   +++   +   LREQ EEE   +    R L  A +
Sbjct: 1337 STEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQA 1396

Query: 1370 EVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVE 1429
            ++++WR + E +A    E  EEA+++ A+  +   + +         LE+ ++RLQ E++
Sbjct: 1397 QLSEWRRRQEEEA-GALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELD 1455

Query: 1430 DLMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELFKVKN 1489
            D  +D+E+     + L+KKQR FD++L+E K        E E ++ E R        +  
Sbjct: 1456 DATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTR 1515

Query: 1490 VYEESLDQLETLRRENKNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALEE 1549
              EE  +  E L R+N+ L+ E+  L     + GK +HELE+  +  EQ   +++A + E
Sbjct: 1516 ALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTE 1575

Query: 1550 AEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHTRVVETMQSTLDAEIR 1609
             E  L   E   LR+++ +  +K++ +R +  +DE  ++ +R   + +   +   D E +
Sbjct: 1576 LEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERK 1635

Query: 1610 SRNDALRVKKKMEGDLNEMEIQLNHANRLAAESLRNYRNTQGILKETQLHLDDALRGQED 1669
             R  A+  +KK+EG+L E++ Q+  A +   E+++  R  Q  +KE    +++    +E+
Sbjct: 1636 QRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREE 1695

Query: 1670 LKEQLAIVERRANLLQAEIEELWATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINT 1729
            +  Q    E+R   L+AE+  L   L  ++R+R+ A+Q+  + ++ V   +    +++  
Sbjct: 1696 IFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEE 1755

Query: 1730 KKKLENDVSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNL 1789
            K++LE  + QL+ E+EE    S    ++ +K +     +  EL  E+  SA  E  ++ L
Sbjct: 1756 KRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQL 1815

Query: 1790 EQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHERR 1849
            E+ +++L+ RL E +  A    K  I  LE+++ + E ++E E +    + K +R+ E+R
Sbjct: 1816 ERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKR 1875

Query: 1850 VKELTYQTEEDRKNVLRLQDLVDKLQAKVKSYKRQAEEAEEQSNANLSKFRKLQHELEEA 1909
            +KE+  Q EE+R+   +L+D ++K   +VK  KRQ EEAEE+++   +  R+LQ ELE+ 
Sbjct: 1876 LKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDV 1935

Query: 1910 EERADIAESQVNKLRVKSR 1928
             E A+    +V  LR + R
Sbjct: 1936 TESAESMNREVTTLRNRLR 1954



 Score =  227 bits (579), Expect = 7e-59
 Identities = 234/997 (23%), Positives = 455/997 (45%), Gaps = 114/997 (11%)

Query: 996  SKEKKALQETHQQTLDDLQAEEDKVNILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAK 1055
            +K K  LQ T Q  +  LQA   ++  + + + +  ++V +L+G + Q       LE  +
Sbjct: 864  TKVKPLLQVTRQDEV--LQARAQELQKVQELQQQSAREVGELQGRVAQ-------LEEER 914

Query: 1056 RKLEGDLKLAQESTMDMENDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQ 1115
             +L   L+   E   + E  + +L  + ++ E  +S L +++ +E+    Q+Q + K LQ
Sbjct: 915  ARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQ 974

Query: 1116 ARIEELGEEIEAERASRAKAEKQRSDLSRELEEISERL---EEAGGATSAQVELNKKREA 1172
              I+EL   +EAE  +R K + ++     ++++  E L   E+     S + +L + R A
Sbjct: 975  QHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLA 1034

Query: 1173 EFQKLRRDLEEATLQHEAMVAALRKKHADSMAELGEQIDNLQRVKQKLEKEKSELKMETD 1232
            EF     + EE        +  LR K+  ++A++          + +L KE+        
Sbjct: 1035 EFSSQAAEEEEKVKS----LNKLRLKYEATIADM----------EDRLRKEE-------- 1072

Query: 1233 DLSSNAEAISKAKGNLEKMCRSLEDQVSELKTKEEEQQRLINDLTAQRARLQTEAGEYSR 1292
                      K +  LEK+ R L+ + SEL+ +  EQQ+   +L AQ  R + E      
Sbjct: 1073 ----------KGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALA 1122

Query: 1293 QLDEKDALVSQLSRSKQASTQQIEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEE 1352
            + +++    +QL +S + +   + E +  LE E  A+       +    + + LR + E+
Sbjct: 1123 RAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELED 1182

Query: 1353 EQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNA 1412
              +     Q   SK   EV + +   E +       ++E +++  Q L E  E +E    
Sbjct: 1183 TLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARR 1242

Query: 1413 KCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQ-AELE 1471
               + EKT+  L+ EV +L  ++     A    ++++R  +  L E + +  + + A  E
Sbjct: 1243 GKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAE 1302

Query: 1472 ASQKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEISDLTEQIAEGGKQIHELEK 1531
            A++K  R+   EL  V     E+  +   L +E  + + ++ D  E + E  +    L  
Sbjct: 1303 AAEKLQRA-QAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGS 1361

Query: 1532 IKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEVD--------------- 1576
              + +E E   ++  LEE  A+ E    ++   Q +L++ +   +               
Sbjct: 1362 RVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRR 1421

Query: 1577 ---------RKIAEKDEEIDQLKRNHTRVVETMQ-STLDAEIRSRNDALRVKKKMEGDLN 1626
                     +++AEK E +D+L+R   R+ + +  +T+D E + +  +   KK+ + D  
Sbjct: 1422 AAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQL 1481

Query: 1627 EMEIQLNHANRLAAESLRNYRNTQGILKETQ-LHLDDALRGQEDLKEQLAIVERRANLLQ 1685
              E     A  L A   R     +G  +E + L L  AL  +++ +E+L   ER+   L+
Sbjct: 1482 LAE---EKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREEL---ERQNRALR 1535

Query: 1686 AEIEELWAT-------LEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVS 1738
            AE+E L ++       + + ER+ ++AEQ   D   +V  L  + T+  + K +LE  V 
Sbjct: 1536 AELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQ 1595

Query: 1739 QLQSEVEEVIQESRNAEEKAK----KAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVK 1794
             L+++ E  +Q    A E+ +    K + DA +  +E +K++  +      +K LE  ++
Sbjct: 1596 ALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAV---AARKKLEGELE 1652

Query: 1795 DLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHERRVKELT 1854
            +L+ ++  A Q   +   KQ++K++A+++EL  EVE  +    E     R+ E+R+K L 
Sbjct: 1653 ELKAQMASAGQ-GKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLE 1711

Query: 1855 YQTEEDRKNVLRLQD-LVDKLQAKVKSYKRQAEEAEEQSNANLSK-------------FR 1900
             +       VLRLQ+ L    +A+ ++ + + E A+E +N NLSK               
Sbjct: 1712 AE-------VLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLG 1764

Query: 1901 KLQHELEEAEERADIAESQVNKLRVKSREVHTKISAE 1937
            +L+ ELEE +  +++   +  KL ++   + T++SAE
Sbjct: 1765 QLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAE 1801



 Score =  219 bits (557), Expect = 3e-56
 Identities = 205/953 (21%), Positives = 425/953 (44%), Gaps = 43/953 (4%)

Query: 838  KIKPL----LKSAETEKEMATMKEEFQKTKDELAKS----EAKRKELEEKMVTLLKEKND 889
            K+K L    LK   T  +M     + +K + EL K     + +  EL+E+MV   +   +
Sbjct: 1046 KVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEE 1105

Query: 890  LQLQVQSEADSLADAEERCE-------QLIKNKIQLEAKIKEVTERAEEEEEINAELTAK 942
            L+ Q+  + + L  A  R E       QL+K+  + +A + E  E  E E     +   +
Sbjct: 1106 LRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQ 1165

Query: 943  KRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKAL 1002
            +R L +E   L+ +++D   TL     ++     + + +TE    L+E         + L
Sbjct: 1166 RRDLGEELEALRGELED---TLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQEL 1222

Query: 1003 QETHQQTLDDLQAEEDKVN----ILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKL 1058
            ++ H Q L +L  + ++         K +  LE +V +L   L   +  R + E+ +R+L
Sbjct: 1223 RQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRL 1282

Query: 1059 EGDLKLAQESTMDMENDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARI 1118
            E  L+  Q    D E  + +  EKL++ + E+ N+   + + ++  I+L K++   +A++
Sbjct: 1283 ELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQL 1342

Query: 1119 EELGEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQVELNKKREAEFQKLR 1178
             +  E ++ E  ++     +   +  E   + E+LEE   A        +  +A+  + R
Sbjct: 1343 HDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWR 1402

Query: 1179 RDLEEATLQHEAMVAALRKKHADS------MAELGEQIDNLQRVKQKLEKEKSELKMETD 1232
            R  EE     EA   A R+   ++      +AE  E +D L+R +++L++E  +  M   
Sbjct: 1403 RRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATM--- 1459

Query: 1233 DLSSNAEAISKAKGNLEKMCRSLEDQVSELKTKEEEQQRLINDLTAQRARLQTEAGEYSR 1292
            DL    + +S  +    K  + L ++ + +    EE++R      A+    +  A   +R
Sbjct: 1460 DLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERA----EAEGREREARALSLTR 1515

Query: 1293 QLDEKDALVSQLSRSKQASTQQIEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEE 1352
             L+E+     +L R  +A   ++E L    ++  K+ + L  A + +    + LR Q  E
Sbjct: 1516 ALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTE 1575

Query: 1353 EQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNA 1412
             ++     + A  +    V   +T++E D   R E  EE +++LA++L++AE   +    
Sbjct: 1576 LEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERK 1635

Query: 1413 KCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQAELEA 1472
            +       +++L+ E+E+L   +  +        K+ R     + E  ++ EET+   E 
Sbjct: 1636 QRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREE 1695

Query: 1473 SQKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEISDLTEQIAEGGKQIHELEKI 1532
               ++R     L  ++       ++L    R  +  QQ+  ++ +++A G      + + 
Sbjct: 1696 IFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEE 1755

Query: 1533 KKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEV--DRKIAEKDEEIDQLK 1590
            K+Q+E    +++  LEE +++ E    +  ++ L++  + +E+  +R  + K E   Q  
Sbjct: 1756 KRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQL 1815

Query: 1591 RNHTRVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEMEIQLNHANRLAAESLRNYRNTQ 1650
                + +       DA  R+R+        +E  L + E QL    R    S +  R  +
Sbjct: 1816 ERQIQELRGRLGEEDAGARARHKMTIAA--LESKLAQAEEQLEQETRERILSGKLVRRAE 1873

Query: 1651 GILKETQLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELWATLEQTERSRKIAEQELL 1710
              LKE  L +++  R  + L++QL     R   L+ ++EE      + +  R+  ++EL 
Sbjct: 1874 KRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELE 1933

Query: 1711 DASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEV--IQESRNAEEKAKKA 1761
            D +E  + ++ + T+L N  ++    ++     V +V  ++E   ++E+A++A
Sbjct: 1934 DVTESAESMNREVTTLRNRLRR--GPLTFTTRTVRQVFRLEEGVASDEEAEEA 1984


>gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens]
          Length = 2036

 Score = 1291 bits (3340), Expect = 0.0
 Identities = 726/1912 (37%), Positives = 1129/1912 (59%), Gaps = 58/1912 (3%)

Query: 67   EGGATLTVREDQVFPMNPPKYDKIEDMAMMTHLHEPGVLYNLKERYAAWMIYTYSGLFCV 126
            E G  L +  DQ+  MNPPK+ K EDMA +T L+E  VL+NL+ERY + +IYTYSGLFCV
Sbjct: 84   ESGRRLRLPRDQIQRMNPPKFSKAEDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCV 143

Query: 127  TVNPYKWLPVYKPEVVAAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAG 186
             +NPYK LP+Y   +V  YRGKKR E PPH++++++ AY+ ML DRE+QSIL TGESGAG
Sbjct: 144  VINPYKQLPIYTEAIVEMYRGKKRHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAG 203

Query: 187  KTVNTKRVIQYFATIAVTGEKKKDE------SGKMQGTLEDQIISANPLLEAFGNAKTVR 240
            KT NTK+VIQY A +A + + +K+       S    G LE Q++ ANP+LEAFGNAKTV+
Sbjct: 204  KTENTKKVIQYLAHVASSPKGRKEPGVPASVSTVSYGELERQLLQANPILEAFGNAKTVK 263

Query: 241  NDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQITSNKKPDL 300
            NDNSSRFGKFIRI+F   G +  A+IETYLLEKSR   Q K E S+HIFYQ+       L
Sbjct: 264  NDNSSRFGKFIRINFDVAGYIVGANIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQL 323

Query: 301  IEMLLITTNPYDYAFVSQGEITVPSIDDQEELMATDSAIDILGFTPEEKVSIYKLTGAVM 360
               LL+    + Y F++ G  + P   ++E    T  ++ +LGF+ EE +S+ ++  AV+
Sbjct: 324  KADLLLEPCSH-YRFLTNGPSSSPG-QERELFQETLESLRVLGFSHEEIISMLRMVSAVL 381

Query: 361  HYGNMKFKQKQREEQAEPDGTEVADKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTV 420
             +GN+  K+++  +QA       A K   L  L   D  +AL  PR+KVG +YV K QT 
Sbjct: 382  QFGNIALKRERNTDQATMPDNTAAQKLCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTK 441

Query: 421  QQVYNAVGALAKAVYEKMFLWMVTRINQQLDTKQPRQ--YFIGVLDIAGFEIFDFNSLEQ 478
            +Q   A+ ALAKA YE++F W+V R+N+ LD + PRQ   F+G+LDIAGFEIF  NS EQ
Sbjct: 442  EQADFALEALAKATYERLFRWLVLRLNRALD-RSPRQGASFLGILDIAGFEIFQLNSFEQ 500

Query: 479  LCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPL---GIFS 535
            LCIN+TNEKLQQ FNH MFVLEQEEY++EGI WTF+DFG+DL  CI+LIE+P    G+ +
Sbjct: 501  LCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGLDLQPCIDLIERPANPPGLLA 560

Query: 536  ILEEECMFPKATDTSFKNKLYDQHLGKSANFQKPKVVKGKAEAHFSLIHYAGTVDYNITG 595
            +L+EEC FPKATD SF  K+  Q  G    FQ+P+ ++ +A+  FS++HYAG VDY    
Sbjct: 561  LLDEECWFPKATDKSFVEKVA-QEQGGHPKFQRPRHLRDQAD--FSVLHYAGKVDYKANE 617

Query: 596  WLDKNKDPLNDTVVGLYQKSAMKTLASLF------------------STYASAEADSSA- 636
            WL KN DPLND V  L  +S  +  A ++                  S   SAE  SSA 
Sbjct: 618  WLMKNMDPLNDNVAALLHQSTDRLTAEIWKDEHGGFQQFSFLGSFPPSPPGSAERCSSAI 677

Query: 637  --------------------KKGAKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCI 676
                                  G + +   F+TV  L++E+L++LM  L +T+P FVRCI
Sbjct: 678  SPPGVEGIVGLEQVSSLGDGPPGGRPRRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCI 737

Query: 677  IPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYGDFKQRYKVLNASAIPEG 736
            +PN  K  G +E  LVL QLRCNGVLEGIRICR+GFP+RIL+ +F+QRY++L  +AIP+G
Sbjct: 738  VPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPKG 797

Query: 737  QFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDEKLAQIITRTQAVCR 796
             F+D K+A EK++ ++++D   Y+ G +K+FF+AG+L  LEE RD K+  II   QA  R
Sbjct: 798  -FMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAAR 856

Query: 797  GFLMRVEYQKMLQRREALFCIQYNVRAFMNVKHWPWMKLFFKIKPLLKSAETEKEMATMK 856
            G+L R  +QK  Q++ AL  +Q N  A++ ++HW W +LF K+KPLL+    ++ +    
Sbjct: 857  GYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARA 916

Query: 857  EEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLADAEERCEQLIKNKI 916
            +E QK ++   +S  +  EL+ ++  L +E+  L  Q+++EA+  A+AEE   +L   K 
Sbjct: 917  QELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQ 976

Query: 917  QLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATEN 976
            +LE  + E+  R  EEEE + ++  +K++L+    EL+  ++  E    K++ EK  TE 
Sbjct: 977  ELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEA 1036

Query: 977  KVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDKVNILTKAKTKLEQQVDD 1036
            K+K   E++  L++  +KLSKE+K L++   +       EE+KV  L K + K E  + D
Sbjct: 1037 KMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIAD 1096

Query: 1037 LEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQLDEKLEKKEFEISNLISK 1096
            +E  L +E+K R +LE+ KR+L+G+    QE  ++ +   ++L  +L +KE E+   +++
Sbjct: 1097 MEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALAR 1156

Query: 1097 IEDEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQRSDLSRELEEISERLEEA 1156
             EDE     QL K ++E QA + E  E++E+ER +R KAEKQR DL  ELE +   LE+ 
Sbjct: 1157 AEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDT 1216

Query: 1157 GGATSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRKKHADSMAELGEQIDNLQRV 1216
              +T+AQ EL  KRE E  +L++ LEE T  HEA V  LR++H  ++ EL EQ++  +R 
Sbjct: 1217 LDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRG 1276

Query: 1217 KQKLEKEKSELKMETDDLSSNAEAISKAKGNLEKMCRSLEDQVSELKTKEEEQQRLINDL 1276
            K   EK +  L+ E  +L +   ++  A+   E+  R LE Q+ E++ +  + +R   + 
Sbjct: 1277 KGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEA 1336

Query: 1277 TAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKHQLEEETKAKNALAHAL 1336
              +  R Q E    S  L+E ++   +LS+   ++  Q+ + +  L+EET+AK AL   +
Sbjct: 1337 AEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRV 1396

Query: 1337 QSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKL 1396
            ++   +   LREQ EEE   +    R L  A +++++WR + E +A    E  EEA+++ 
Sbjct: 1397 RAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEA-GALEAGEEARRRA 1455

Query: 1397 AQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVL 1456
            A+  +   + +         LE+ ++RLQ E++D  +D+E+     + L+KKQR FD++L
Sbjct: 1456 AREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLL 1515

Query: 1457 SEWKQKYEETQAELEASQKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEISDLT 1516
            +E K        E E ++ E R        +    EE  +  E L R+N+ L+ E+  L 
Sbjct: 1516 AEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALL 1575

Query: 1517 EQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEVD 1576
                + GK +HELE+  +  EQ   +++A + E E  L   E   LR+++ +  +K++ +
Sbjct: 1576 SSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHE 1635

Query: 1577 RKIAEKDEEIDQLKRNHTRVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEMEIQLNHAN 1636
            R +  +DE  ++ +R   + +   +   D E + R  A+  +KK+EG+L E++ Q+  A 
Sbjct: 1636 RDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAG 1695

Query: 1637 RLAAESLRNYRNTQGILKETQLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELWATLE 1696
            +   E+++  R  Q  +KE    +++    +E++  Q    E+R   L+AE+  L   L 
Sbjct: 1696 QGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELA 1755

Query: 1697 QTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQESRNAEE 1756
             ++R+R+ A+Q+  + ++ V   +    +++  K++LE  + QL+ E+EE    S    +
Sbjct: 1756 ASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLND 1815

Query: 1757 KAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQ 1816
            + +K +     +  EL  E+  SA  E  ++ LE+ +++L+ RL E +  A    K  I 
Sbjct: 1816 RYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIA 1875

Query: 1817 KLEARVRELEGEVENEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQA 1876
             LE+++ + E ++E E +    + K +R+ E+R+KE+  Q EE+R+   +L+D ++K   
Sbjct: 1876 ALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNL 1935

Query: 1877 KVKSYKRQAEEAEEQSNANLSKFRKLQHELEEAEERADIAESQVNKLRVKSR 1928
            +VK  KRQ EEAEE+++   +  R+LQ ELE+  E A+    +V  LR + R
Sbjct: 1936 RVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLR 1987



 Score =  227 bits (579), Expect = 7e-59
 Identities = 234/997 (23%), Positives = 455/997 (45%), Gaps = 114/997 (11%)

Query: 996  SKEKKALQETHQQTLDDLQAEEDKVNILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAK 1055
            +K K  LQ T Q  +  LQA   ++  + + + +  ++V +L+G + Q       LE  +
Sbjct: 897  TKVKPLLQVTRQDEV--LQARAQELQKVQELQQQSAREVGELQGRVAQ-------LEEER 947

Query: 1056 RKLEGDLKLAQESTMDMENDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQ 1115
             +L   L+   E   + E  + +L  + ++ E  +S L +++ +E+    Q+Q + K LQ
Sbjct: 948  ARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQ 1007

Query: 1116 ARIEELGEEIEAERASRAKAEKQRSDLSRELEEISERL---EEAGGATSAQVELNKKREA 1172
              I+EL   +EAE  +R K + ++     ++++  E L   E+     S + +L + R A
Sbjct: 1008 QHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLA 1067

Query: 1173 EFQKLRRDLEEATLQHEAMVAALRKKHADSMAELGEQIDNLQRVKQKLEKEKSELKMETD 1232
            EF     + EE        +  LR K+  ++A++          + +L KE+        
Sbjct: 1068 EFSSQAAEEEEKVKS----LNKLRLKYEATIADM----------EDRLRKEE-------- 1105

Query: 1233 DLSSNAEAISKAKGNLEKMCRSLEDQVSELKTKEEEQQRLINDLTAQRARLQTEAGEYSR 1292
                      K +  LEK+ R L+ + SEL+ +  EQQ+   +L AQ  R + E      
Sbjct: 1106 ----------KGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALA 1155

Query: 1293 QLDEKDALVSQLSRSKQASTQQIEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEE 1352
            + +++    +QL +S + +   + E +  LE E  A+       +    + + LR + E+
Sbjct: 1156 RAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELED 1215

Query: 1353 EQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNA 1412
              +     Q   SK   EV + +   E +       ++E +++  Q L E  E +E    
Sbjct: 1216 TLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARR 1275

Query: 1413 KCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQ-AELE 1471
               + EKT+  L+ EV +L  ++     A    ++++R  +  L E + +  + + A  E
Sbjct: 1276 GKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAE 1335

Query: 1472 ASQKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEISDLTEQIAEGGKQIHELEK 1531
            A++K  R+   EL  V     E+  +   L +E  + + ++ D  E + E  +    L  
Sbjct: 1336 AAEKLQRA-QAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGS 1394

Query: 1532 IKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEVD--------------- 1576
              + +E E   ++  LEE  A+ E    ++   Q +L++ +   +               
Sbjct: 1395 RVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRR 1454

Query: 1577 ---------RKIAEKDEEIDQLKRNHTRVVETMQ-STLDAEIRSRNDALRVKKKMEGDLN 1626
                     +++AEK E +D+L+R   R+ + +  +T+D E + +  +   KK+ + D  
Sbjct: 1455 AAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQL 1514

Query: 1627 EMEIQLNHANRLAAESLRNYRNTQGILKETQ-LHLDDALRGQEDLKEQLAIVERRANLLQ 1685
              E     A  L A   R     +G  +E + L L  AL  +++ +E+L   ER+   L+
Sbjct: 1515 LAE---EKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREEL---ERQNRALR 1568

Query: 1686 AEIEELWAT-------LEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVS 1738
            AE+E L ++       + + ER+ ++AEQ   D   +V  L  + T+  + K +LE  V 
Sbjct: 1569 AELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQ 1628

Query: 1739 QLQSEVEEVIQESRNAEEKAK----KAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVK 1794
             L+++ E  +Q    A E+ +    K + DA +  +E +K++  +      +K LE  ++
Sbjct: 1629 ALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAV---AARKKLEGELE 1685

Query: 1795 DLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHERRVKELT 1854
            +L+ ++  A Q   +   KQ++K++A+++EL  EVE  +    E     R+ E+R+K L 
Sbjct: 1686 ELKAQMASAGQ-GKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLE 1744

Query: 1855 YQTEEDRKNVLRLQD-LVDKLQAKVKSYKRQAEEAEEQSNANLSK-------------FR 1900
             +       VLRLQ+ L    +A+ ++ + + E A+E +N NLSK               
Sbjct: 1745 AE-------VLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLG 1797

Query: 1901 KLQHELEEAEERADIAESQVNKLRVKSREVHTKISAE 1937
            +L+ ELEE +  +++   +  KL ++   + T++SAE
Sbjct: 1798 QLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAE 1834



 Score =  219 bits (557), Expect = 3e-56
 Identities = 205/953 (21%), Positives = 425/953 (44%), Gaps = 43/953 (4%)

Query: 838  KIKPL----LKSAETEKEMATMKEEFQKTKDELAKS----EAKRKELEEKMVTLLKEKND 889
            K+K L    LK   T  +M     + +K + EL K     + +  EL+E+MV   +   +
Sbjct: 1079 KVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEE 1138

Query: 890  LQLQVQSEADSLADAEERCE-------QLIKNKIQLEAKIKEVTERAEEEEEINAELTAK 942
            L+ Q+  + + L  A  R E       QL+K+  + +A + E  E  E E     +   +
Sbjct: 1139 LRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQ 1198

Query: 943  KRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKAL 1002
            +R L +E   L+ +++D   TL     ++     + + +TE    L+E         + L
Sbjct: 1199 RRDLGEELEALRGELED---TLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQEL 1255

Query: 1003 QETHQQTLDDLQAEEDKVN----ILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKL 1058
            ++ H Q L +L  + ++         K +  LE +V +L   L   +  R + E+ +R+L
Sbjct: 1256 RQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRL 1315

Query: 1059 EGDLKLAQESTMDMENDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARI 1118
            E  L+  Q    D E  + +  EKL++ + E+ N+   + + ++  I+L K++   +A++
Sbjct: 1316 ELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQL 1375

Query: 1119 EELGEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQVELNKKREAEFQKLR 1178
             +  E ++ E  ++     +   +  E   + E+LEE   A        +  +A+  + R
Sbjct: 1376 HDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWR 1435

Query: 1179 RDLEEATLQHEAMVAALRKKHADS------MAELGEQIDNLQRVKQKLEKEKSELKMETD 1232
            R  EE     EA   A R+   ++      +AE  E +D L+R +++L++E  +  M   
Sbjct: 1436 RRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATM--- 1492

Query: 1233 DLSSNAEAISKAKGNLEKMCRSLEDQVSELKTKEEEQQRLINDLTAQRARLQTEAGEYSR 1292
            DL    + +S  +    K  + L ++ + +    EE++R      A+    +  A   +R
Sbjct: 1493 DLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERA----EAEGREREARALSLTR 1548

Query: 1293 QLDEKDALVSQLSRSKQASTQQIEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEE 1352
             L+E+     +L R  +A   ++E L    ++  K+ + L  A + +    + LR Q  E
Sbjct: 1549 ALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTE 1608

Query: 1353 EQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNA 1412
             ++     + A  +    V   +T++E D   R E  EE +++LA++L++AE   +    
Sbjct: 1609 LEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERK 1668

Query: 1413 KCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQAELEA 1472
            +       +++L+ E+E+L   +  +        K+ R     + E  ++ EET+   E 
Sbjct: 1669 QRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREE 1728

Query: 1473 SQKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEISDLTEQIAEGGKQIHELEKI 1532
               ++R     L  ++       ++L    R  +  QQ+  ++ +++A G      + + 
Sbjct: 1729 IFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEE 1788

Query: 1533 KKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEV--DRKIAEKDEEIDQLK 1590
            K+Q+E    +++  LEE +++ E    +  ++ L++  + +E+  +R  + K E   Q  
Sbjct: 1789 KRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQL 1848

Query: 1591 RNHTRVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEMEIQLNHANRLAAESLRNYRNTQ 1650
                + +       DA  R+R+        +E  L + E QL    R    S +  R  +
Sbjct: 1849 ERQIQELRGRLGEEDAGARARHKMTIAA--LESKLAQAEEQLEQETRERILSGKLVRRAE 1906

Query: 1651 GILKETQLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELWATLEQTERSRKIAEQELL 1710
              LKE  L +++  R  + L++QL     R   L+ ++EE      + +  R+  ++EL 
Sbjct: 1907 KRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELE 1966

Query: 1711 DASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEV--IQESRNAEEKAKKA 1761
            D +E  + ++ + T+L N  ++    ++     V +V  ++E   ++E+A++A
Sbjct: 1967 DVTESAESMNREVTTLRNRLRR--GPLTFTTRTVRQVFRLEEGVASDEEAEEA 2017


>gi|153945715 myosin VC [Homo sapiens]
          Length = 1742

 Score =  608 bits (1567), Expect = e-173
 Identities = 441/1438 (30%), Positives = 722/1438 (50%), Gaps = 108/1438 (7%)

Query: 40   VFVAEPKESYVKSTIQS--KEGGKVT-VKTEGGATL--TVREDQVFPM-NPPKYDKIEDM 93
            V++ +P+E +  + I    + G KV  +  E G  L  +V  + + P+ NP       D+
Sbjct: 13   VWIPDPEEVWKSAEIAKDYRVGDKVLRLLLEDGTELDYSVNPESLPPLRNPDILVGENDL 72

Query: 94   AMMTHLHEPGVLYNLKERYA-AWMIYTYSGLFCVTVNPYKWLPVYKPEVVAAYRGKKRQE 152
              +++LHEP VL+NL+ R+A + +IYTYSG+  V +NPYK LP+Y   ++ AY G+   +
Sbjct: 73   TALSYLHEPAVLHNLRIRFAESKLIYTYSGIILVAMNPYKQLPIYGDAIIHAYSGQNMGD 132

Query: 153  APPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKDES 212
              PHIF++++ AY+ M  +  NQSI+++GESGAGKTV+ +  ++YFAT++ +G       
Sbjct: 133  MDPHIFAVAEEAYKQMARNNRNQSIIVSGESGAGKTVSARYAMRYFATVSKSGSNAH--- 189

Query: 213  GKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLE 272
                  +ED+++++NP+ EA GNAKT RNDNSSRFGK+  I F    ++  A++ TYLLE
Sbjct: 190  ------VEDKVLASNPITEAVGNAKTTRNDNSSRFGKYTEISFDEQNQIIGANMSTYLLE 243

Query: 273  KSRVTFQLKAERSYHIFYQI-TSNKKPDLIEMLLITTNPYDYAFVSQGEITVPSIDDQEE 331
            KSRV FQ + ER+YHIFYQ+  S ++ +   + L +   ++Y  +  G   +  ++D+ E
Sbjct: 244  KSRVVFQSENERNYHIFYQLCASAQQSEFKHLKLGSAEEFNYTRMG-GNTVIEGVNDRAE 302

Query: 332  LMATDSAIDILGFTPEEKVSIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKAAYLQ 391
            ++ T     +LGF  + ++ ++K+  A++H GN++      E  +  +          L 
Sbjct: 303  MVETQKTFTLLGFKEDFQMDVFKILAAILHLGNVQITAVGNERSSVSEDDSHLKVFCELL 362

Query: 392  SLNSADLLKALCYPRVKVGNEYVTKGQTVQQVYNAVGALAKAVYEKMFLWMVTRINQQLD 451
             L S  + + LC  ++   +E V K  T  Q  NA  ALAK +Y  +F ++V RINQ L 
Sbjct: 363  GLESGRVAQWLCNRKIVTSSETVVKPMTRPQAVNARDALAKKIYAHLFDFIVERINQALQ 422

Query: 452  TKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEW 511
                +  FIGVLDI GFE FD NS EQ CIN+ NEKLQQ FN H+F LEQEEY KE I W
Sbjct: 423  FSGKQHTFIGVLDIYGFETFDVNSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEDIPW 482

Query: 512  TFIDFGMDLAACIELIEKPLGIFSILEEECMFPKATDTSFKNKLYDQHLGKSANFQKPKV 571
            T IDF  D    I+LIE  +GI  +L+EEC+ P  TD ++  KLY+  + ++  F+KP++
Sbjct: 483  TLIDF-YDNQPVIDLIEAKMGILELLDEECLLPHGTDENWLQKLYNNFVNRNPLFEKPRM 541

Query: 572  VKGKAEAHFSLIHYAGTVDYNITGWLDKNKDPLNDTVVGLYQKSAMKTLASLF------- 624
                +   F + H+A  V+Y   G+L+KN+D + D +V + + S     A+ F       
Sbjct: 542  ----SNTSFVIQHFADKVEYKCEGFLEKNRDTVYDMLVEILRASKFHLCANFFQENPTPP 597

Query: 625  STYASAEADSSAKKGAKKKGSSFQ-TVSALFRENLNKLMTNLRSTHPHFVRCIIPNETKT 683
            S + S     SAK+  K     F+ TV + FR +L  LM  L +T PH+VRCI PN+ K 
Sbjct: 598  SPFGSMITVKSAKQVIKPNSKHFRTTVGSKFRSSLYLLMETLNATTPHYVRCIKPNDEKL 657

Query: 684  PGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYGDFKQRYKVLNASAIPEGQFIDSKK 743
            P   + + ++ QLR  GVLE IRI  + +PSR  Y +F  RY +L      E  F D K+
Sbjct: 658  PFEFDSKRIVQQLRACGVLETIRISAQSYPSRWTYIEFYSRYGILMTK--QELSFSDKKE 715

Query: 744  ASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDEKLAQIITRTQAVCRGFLMRVE 803
              + +L  +  D  QY+FG TK+FF+AG +  LE++R +KL Q     Q   RG+L R  
Sbjct: 716  VCKVVLHRLIQDSNQYQFGKTKIFFRAGQVAYLEKLRLDKLRQSCVMVQKHMRGWLQR-- 773

Query: 804  YQKMLQRREALFCIQYNVRAFMNVK--------HWPWMKLFFKIK---PLLKSAETEKEM 852
             +K L+ R A   IQ   R    V+           W  +  +      L++S      M
Sbjct: 774  -KKFLRERRAALIIQQYFRGQQTVRKAITAVALKEAWAAIIIQKHCRGYLVRSLYQLIRM 832

Query: 853  ATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLADAEERCEQLI 912
            AT+      T    ++    R+   +    +L+E   + LQ  + A       +   + +
Sbjct: 833  ATI------TMQAYSRGFLARRRYRK----MLEEHKAVILQKYARAWLARRRFQSIRRFV 882

Query: 913  KNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKH 972
             N IQL  +++ + ++ E++ + N  L  K   L    +   + I  LE  L K    + 
Sbjct: 883  LN-IQLTYRVQRLQKKLEDQNKENHGLVEKLTSLAALRAGDVEKIQKLEAELEKAATHRR 941

Query: 973  ATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDKVNILTKAKTKLEQ 1032
              E K K   +    ++E +AKL K    L+   +Q    LQ + +++      K K++ 
Sbjct: 942  NYEEKGKRYRD---AVEEKLAKLQKHNSELETQKEQIQLKLQEKTEEL------KEKMDN 992

Query: 1033 QVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQLDEKLEKKEFEISN 1092
                L   +++E++ RM LE          K  +  T D E   Q L E+++  + E   
Sbjct: 993  LTKQLFDDVQKEERQRMLLE----------KSFELKTQDYEKQIQSLKEEIKALKDEKMQ 1042

Query: 1093 LISKIEDEQAVEIQLQKKIKELQARIEELGE---EIEAERASRAKAEK----QRSDLSRE 1145
            L   +E E      L+ ++  L  +++ + E   EIE  +A +   EK    Q+ ++  +
Sbjct: 1043 LQHLVEGEHVTSDGLKAEVARLSKQVKTISEFEKEIELLQAQKIDVEKHVQSQKREMREK 1102

Query: 1146 LEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRKKHADSMAE 1205
            + EI+++L E+      +  L+ +          DLE      E   A    K A  + E
Sbjct: 1103 MSEITKQLLESYDIEDVRSRLSVE----------DLEHLNEDGELWFAYEGLKKATRVLE 1152

Query: 1206 LGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGNLEKMCRSLEDQVSELKTK 1265
                  + Q  K   EKE   L  +   LS     + K       +  S+  +V+ L ++
Sbjct: 1153 -----SHFQSQKDCYEKEIEALNFKVVHLSQEINHLQKLFREENDINESIRHEVTRLTSE 1207

Query: 1266 E---EEQQRLINDLTAQRARLQTEAGEYSRQLDEK-DALVSQLSRSKQASTQQIEELKHQ 1321
                 + ++ I++L  Q+  L+    E + ++  K + L +QL RS++    Q + L+ Q
Sbjct: 1208 NMMIPDFKQQISELEKQKQDLEIRLNEQAEKMKGKLEELSNQLHRSQEEEGTQRKALEAQ 1267

Query: 1322 LEEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETD 1381
             E  TK K  L   +Q  +   D L++Q+E E E K   ++  S+   E      + E D
Sbjct: 1268 NEIHTKEKEKLIDKIQEMQEASDHLKKQFETESEVKCNFRQEASRLTLENRD--LEEELD 1325

Query: 1382 AIQRT-EELEEAKKKLAQRLQEAEEHVEAVNAK--CASLEKTKQRLQNEVEDLMLDVE 1436
               R  ++L++  K L++ + +A +   +   K     L+  ++     +++L+LD++
Sbjct: 1326 MKDRVIKKLQDQVKTLSKTIGKANDVHSSSGPKEYLGMLQYKREDEAKLIQNLILDLK 1383



 Score = 93.6 bits (231), Expect = 2e-18
 Identities = 134/650 (20%), Positives = 277/650 (42%), Gaps = 110/650 (16%)

Query: 792  QAVCRGFLMRVEYQKMLQRREALFCIQY-----NVRAFMNVKHWPW-MKLFFKIKPLLKS 845
            QA  RGFL R  Y+KML+  +A+   +Y       R F +++ +   ++L ++++ L K 
Sbjct: 838  QAYSRGFLARRRYRKMLEEHKAVILQKYARAWLARRRFQSIRRFVLNIQLTYRVQRLQKK 897

Query: 846  AETEKE-----------MATMK----EEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDL 890
             E + +           +A ++    E+ QK + EL K+   R+  EEK     K   D 
Sbjct: 898  LEDQNKENHGLVEKLTSLAALRAGDVEKIQKLEAELEKAATHRRNYEEKG----KRYRD- 952

Query: 891  QLQVQSEADSLADAEERCEQLIKNKIQLEAKIKEVTERAEEEEE-------INAELTAKK 943
                 +  + LA  ++   +L   K Q++ K++E TE  +E+ +        + +   ++
Sbjct: 953  -----AVEEKLAKLQKHNSELETQKEQIQLKLQEKTEELKEKMDNLTKQLFDDVQKEERQ 1007

Query: 944  RKLEDECSELK-----KDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLSKE 998
            R L ++  ELK     K I  L+  +  ++ EK   ++ V+       GL   +A+LSK+
Sbjct: 1008 RMLLEKSFELKTQDYEKQIQSLKEEIKALKDEKMQLQHLVEGEHVTSDGLKAEVARLSKQ 1067

Query: 999  KKALQETHQQTLDDLQAEE-DKVNILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRK 1057
             K + E  ++ ++ LQA++ D    +   K ++ +++ ++   L +      D+E  + +
Sbjct: 1068 VKTISE-FEKEIELLQAQKIDVEKHVQSQKREMREKMSEITKQLLES----YDIEDVRSR 1122

Query: 1058 L----------EGDLKLAQES--------TMDMENDKQQLDEKLEKKEFEISNLISKIED 1099
            L          +G+L  A E             ++ K   ++++E   F++ +L  +I  
Sbjct: 1123 LSVEDLEHLNEDGELWFAYEGLKKATRVLESHFQSQKDCYEKEIEALNFKVVHLSQEINH 1182

Query: 1100 EQAV---EIQLQKKIKELQARIEELGEEIEAERASRAKAEKQRSDLSRELEEISERLEEA 1156
             Q +   E  + + I+    R+      I   +   ++ EKQ+ DL   L E +E+++  
Sbjct: 1183 LQKLFREENDINESIRHEVTRLTSENMMIPDFKQQISELEKQKQDLEIRLNEQAEKMKGK 1242

Query: 1157 GGATSAQVELNKKREAEFQK-LRRDLEEATLQHEAMVAALRKKHADSMAELGEQIDNLQR 1215
                S Q+  +++ E   +K L    E  T + E ++  +++   ++   L +Q +    
Sbjct: 1243 LEELSNQLHRSQEEEGTQRKALEAQNEIHTKEKEKLIDKIQEMQ-EASDHLKKQFETESE 1301

Query: 1216 VKQKLEKEKSELKMETDDLSSNAEAISKAKGNLEKMCRSLEDQVSE-------------- 1261
            VK    +E S L +E  DL    +   +    L+   ++L   + +              
Sbjct: 1302 VKCNFRQEASRLTLENRDLEEELDMKDRVIKKLQDQVKTLSKTIGKANDVHSSSGPKEYL 1361

Query: 1262 --LKTKEEEQQRLINDLTAQ--------------RARLQTEAGEYSRQLDEKDALVSQLS 1305
              L+ K E++ +LI +L                  A +      Y+  L++ + L S ++
Sbjct: 1362 GMLQYKREDEAKLIQNLILDLKPRGVVVNMIPGLPAHILFMCVRYADSLNDANMLKSLMN 1421

Query: 1306 RSKQASTQQIEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEEEQE 1355
             +       I  +K  ++E  +    L+  L ++ H  + L+ QY  E+E
Sbjct: 1422 ST-------INGIKQVVKEHLEDFEMLSFWLSNTCHFLNCLK-QYSGEEE 1463



 Score = 85.5 bits (210), Expect = 5e-16
 Identities = 123/482 (25%), Positives = 207/482 (42%), Gaps = 69/482 (14%)

Query: 1213 LQRVKQKLEKEKSELKMETDDLSS-------NAEAISKAKGNLEKMC---RSLEDQVSEL 1262
            +QR+++KLE +  E     + L+S       + E I K +  LEK     R+ E++    
Sbjct: 891  VQRLQKKLEDQNKENHGLVEKLTSLAALRAGDVEKIQKLEAELEKAATHRRNYEEKGKRY 950

Query: 1263 KTKEEEQ----QRLINDLTAQRARLQTEAGEYSRQLDEK-DALVSQ-------------- 1303
            +   EE+    Q+  ++L  Q+ ++Q +  E + +L EK D L  Q              
Sbjct: 951  RDAVEEKLAKLQKHNSELETQKEQIQLKLQEKTEELKEKMDNLTKQLFDDVQKEERQRML 1010

Query: 1304 LSRSKQASTQQIEELKHQLEEETKA----KNALAHALQSSRHDCDLLREQYEEEQEGKAE 1359
            L +S +  TQ  E+    L+EE KA    K  L H ++      D L          KAE
Sbjct: 1011 LEKSFELKTQDYEKQIQSLKEEIKALKDEKMQLQHLVEGEHVTSDGL----------KAE 1060

Query: 1360 LQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEK 1419
            + R LSK    ++++  + E   + + ++++  K   +Q+ +  E+  E       S + 
Sbjct: 1061 VAR-LSKQVKTISEFEKEIE---LLQAQKIDVEKHVQSQKREMREKMSEITKQLLESYDI 1116

Query: 1420 TKQRLQNEVEDLMLDVERSNA--ACAALDKKQRNFDKVLSEWKQKYEETQAELEASQKES 1477
               R +  VEDL    E      A   L K  R  +      K  YE+   E+EA   + 
Sbjct: 1117 EDVRSRLSVEDLEHLNEDGELWFAYEGLKKATRVLESHFQSQKDCYEK---EIEALNFKV 1173

Query: 1478 RSLSTELFKVKNVYEESLDQLETLRRENKNLQQE---ISDLTEQIAEGGKQIHELE-KIK 1533
              LS E+  ++ ++ E  D  E++R E   L  E   I D  +QI+E  KQ  +LE ++ 
Sbjct: 1174 VHLSQEINHLQKLFREENDINESIRHEVTRLTSENMMIPDFKQQISELEKQKQDLEIRLN 1233

Query: 1534 KQVEQEKCEIQAALEEAEASLEHE--EGKILRIQLELN-QVKSEVDRKIAEKDEEIDQLK 1590
            +Q E+ K +++    +   S E E  + K L  Q E++ + K ++  KI E  E  D LK
Sbjct: 1234 EQAEKMKGKLEELSNQLHRSQEEEGTQRKALEAQNEIHTKEKEKLIDKIQEMQEASDHLK 1293

Query: 1591 RNHTRVVETM------QSTLDAEIRSRNDAL----RVKKKMEGDLNEMEIQLNHANRLAA 1640
            +      E         S L  E R   + L    RV KK++  +  +   +  AN + +
Sbjct: 1294 KQFETESEVKCNFRQEASRLTLENRDLEEELDMKDRVIKKLQDQVKTLSKTIGKANDVHS 1353

Query: 1641 ES 1642
             S
Sbjct: 1354 SS 1355



 Score = 79.7 bits (195), Expect = 3e-14
 Identities = 115/571 (20%), Positives = 245/571 (42%), Gaps = 77/571 (13%)

Query: 1290 YSRQLDEKDALVSQ------LSRSKQAS----------TQQIEELKHQLEEETKAKNALA 1333
            Y + L+E  A++ Q      L+R +  S          T +++ L+ +LE++ K  + L 
Sbjct: 850  YRKMLEEHKAVILQKYARAWLARRRFQSIRRFVLNIQLTYRVQRLQKKLEDQNKENHGLV 909

Query: 1334 HALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAK 1393
              L S      L     E+ Q+ +AEL++A        A  R  YE    +  + +EE  
Sbjct: 910  EKLTSL---AALRAGDVEKIQKLEAELEKA--------ATHRRNYEEKGKRYRDAVEEKL 958

Query: 1394 KKLAQRLQEAEEHVEAVNAKCAS-LEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNF 1452
             KL +   E E   E +  K     E+ K+++ N  + L  DV++       L+K     
Sbjct: 959  AKLQKHNSELETQKEQIQLKLQEKTEELKEKMDNLTKQLFDDVQKEERQRMLLEKS---- 1014

Query: 1453 DKVLSEWKQKYEETQAELEASQKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEI 1512
                  ++ K ++ + ++++ ++E ++L  E  +++++ E            +  L+ E+
Sbjct: 1015 ------FELKTQDYEKQIQSLKEEIKALKDEKMQLQHLVEGE-------HVTSDGLKAEV 1061

Query: 1513 SDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVK 1572
            + L++Q+    K I E EK  + ++ +K +++  ++  +  +  +  +I +  LE   ++
Sbjct: 1062 ARLSKQV----KTISEFEKEIELLQAQKIDVEKHVQSQKREMREKMSEITKQLLESYDIE 1117

Query: 1573 SEVDRKIAEKDEEIDQ----------LKRNHTRVVET-MQSTLDAEIRSRNDALRVKKKM 1621
                R   E  E +++          LK+  TRV+E+  QS  D       +AL  K   
Sbjct: 1118 DVRSRLSVEDLEHLNEDGELWFAYEGLKKA-TRVLESHFQSQKDC-YEKEIEALNFK--- 1172

Query: 1622 EGDLNEMEIQLNHANRLAAESL---RNYRNTQGILKETQLHLDDALRGQEDLKEQLAIVE 1678
               +  +  ++NH  +L  E      + R+    L    + + D  +   +L++Q   +E
Sbjct: 1173 ---VVHLSQEINHLQKLFREENDINESIRHEVTRLTSENMMIPDFKQQISELEKQKQDLE 1229

Query: 1679 RRANLLQAEIEELWATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVS 1738
             R N    + E++   LE+       +++E  + ++R + L  QN      K+KL + + 
Sbjct: 1230 IRLN---EQAEKMKGKLEELSNQLHRSQEE--EGTQR-KALEAQNEIHTKEKEKLIDKIQ 1283

Query: 1739 QLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQH 1798
            ++Q   + + ++     E       +A+ +  E +  ++     +R+ K L+  VK L  
Sbjct: 1284 EMQEASDHLKKQFETESEVKCNFRQEASRLTLENRDLEEELDMKDRVIKKLQDQVKTLSK 1343

Query: 1799 RLDEAEQLALKGGKKQIQKLEARVRELEGEV 1829
             + +A  +    G K+   +    RE E ++
Sbjct: 1344 TIGKANDVHSSSGPKEYLGMLQYKREDEAKL 1374



 Score = 69.3 bits (168), Expect = 3e-11
 Identities = 95/511 (18%), Positives = 213/511 (41%), Gaps = 57/511 (11%)

Query: 1449 QRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELFKVKNVY--EESLDQLETLRRENK 1506
            +R + K+L E K    +  A    +++  +S+   +  ++  Y  +    +LE   +EN 
Sbjct: 847  RRRYRKMLEEHKAVILQKYARAWLARRRFQSIRRFVLNIQLTYRVQRLQKKLEDQNKENH 906

Query: 1507 NLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQL 1566
             L ++++ L    A   ++I +LE   ++    +   +   +    ++E +  K+ +   
Sbjct: 907  GLVEKLTSLAALRAGDVEKIQKLEAELEKAATHRRNYEEKGKRYRDAVEEKLAKLQKHNS 966

Query: 1567 ELNQVKSEVDRKIAEKDEEIDQLKRNHTRVVETMQSTLDAEIRSRNDALRVKKKMEGDLN 1626
            EL   K ++  K+ EK EE+ +   N T+ +       D   +     + ++K  E    
Sbjct: 967  ELETQKEQIQLKLQEKTEELKEKMDNLTKQL------FDDVQKEERQRMLLEKSFELKTQ 1020

Query: 1627 EMEIQLNHANRLAAESLRNYRNTQGILKETQLHLDDALRGQ----EDLKEQLAIVERRAN 1682
            + E Q+           ++ +     LK+ ++ L   + G+    + LK ++A + ++  
Sbjct: 1021 DYEKQI-----------QSLKEEIKALKDEKMQLQHLVEGEHVTSDGLKAEVARLSKQVK 1069

Query: 1683 LL---QAEIEELWATLEQTERSRKIAEQELLDASERV--QLLHTQNTSLINTKKKLENDV 1737
             +   + EIE L A     E+  +  ++E+ +    +  QLL + +   + ++  +E D+
Sbjct: 1070 TISEFEKEIELLQAQKIDVEKHVQSQKREMREKMSEITKQLLESYDIEDVRSRLSVE-DL 1128

Query: 1738 SQLQSE----------------VEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAH 1781
              L  +                +E   Q  ++  EK  +A+    +    L +E +    
Sbjct: 1129 EHLNEDGELWFAYEGLKKATRVLESHFQSQKDCYEKEIEALNFKVV---HLSQEINHLQK 1185

Query: 1782 LERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVK 1841
            L R + ++ ++++    RL  +E + +   K+QI +LE + ++LE  +  + ++    ++
Sbjct: 1186 LFREENDINESIRHEVTRLT-SENMMIPDFKQQISELEKQKQDLEIRLNEQAEKMKGKLE 1244

Query: 1842 GLRKHERRVKE--------LTYQTEEDRKNVLRLQDLVDKLQAKVKSYKRQAEEAEEQSN 1893
             L     R +E        L  Q E   K   +L D + ++Q      K+Q E   E   
Sbjct: 1245 ELSNQLHRSQEEEGTQRKALEAQNEIHTKEKEKLIDKIQEMQEASDHLKKQFETESEVKC 1304

Query: 1894 ANLSKFRKLQHELEEAEERADIAESQVNKLR 1924
                +  +L  E  + EE  D+ +  + KL+
Sbjct: 1305 NFRQEASRLTLENRDLEEELDMKDRVIKKLQ 1335


>gi|215982791 myosin VA isoform 1 [Homo sapiens]
          Length = 1855

 Score =  592 bits (1527), Expect = e-169
 Identities = 454/1560 (29%), Positives = 762/1560 (48%), Gaps = 141/1560 (9%)

Query: 40   VFVAEPKESYVKSTIQS--KEGGKVTV-KTEGGATLTVRED---QVFP--MNPPKYDKIE 91
            V++ +P+E +  + +    K G KV +   E G  L    D   +  P   NP       
Sbjct: 13   VWIPDPEEVWKSAELLKDYKPGDKVLLLHLEEGKDLEYHLDPKTKELPHLRNPDILVGEN 72

Query: 92   DMAMMTHLHEPGVLYNLKERYA-AWMIYTYSGLFCVTVNPYKWLPVYKPEVVAAYRGKKR 150
            D+  +++LHEP VL+NL+ R+  + +IYTY G+  V +NPY+ LP+Y  +++ AY G+  
Sbjct: 73   DLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAYSGQNM 132

Query: 151  QEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKD 210
             +  PHIF++++ AY+ M  D  NQSI+++GESGAGKTV+ K  ++YFAT++ +      
Sbjct: 133  GDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGSAS---- 188

Query: 211  ESGKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYL 270
                 +  +E++++++NP++E+ GNAKT RNDNSSRFGK+I I F    ++  A++ TYL
Sbjct: 189  -----EANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMRTYL 243

Query: 271  LEKSRVTFQLKAERSYHIFYQITSNKKPDLIEMLLITTNPYDYAFVSQG-EITVPSIDDQ 329
            LEKSRV FQ + ER+YHIFYQ+ ++ K    +ML +  N  ++ +  QG    +  +DD 
Sbjct: 244  LEKSRVVFQAEEERNYHIFYQLCASAKLPEFKMLRLG-NADNFNYTKQGGSPVIEGVDDA 302

Query: 330  EELMATDSAIDILGFTPEEKVSIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKAAY 389
            +E+  T  A  +LG +   ++ I+++   ++H GN+ F  +  +    P   E       
Sbjct: 303  KEMAHTRQACTLLGISESHQMGIFRILAGILHLGNVGFTSRDADSCTIPPKHEPLCIFCD 362

Query: 390  LQSLNSADLLKALCYPRVKVGNEYVTKGQTVQQVYNAVGALAKAVYEKMFLWMVTRINQQ 449
            L  ++  ++   LC+ ++    E   K  +  Q  NA  ALAK +Y K+F W+V  +NQ 
Sbjct: 363  LMGVDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVDNVNQA 422

Query: 450  LDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGI 509
            L +   +  FIGVLDI GFE F+ NS EQ CIN+ NEKLQQ FN H+F LEQEEY KE I
Sbjct: 423  LHSAVKQHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEQI 482

Query: 510  EWTFIDFGMDLAACIELIEKPLGIFSILEEECMFPKATDTSFKNKLYDQHLGKSANFQKP 569
             WT IDF  D   CI LIE  LGI  +L+EEC  PK TD ++  KLY+ HL K A F+KP
Sbjct: 483  PWTLIDF-YDNQPCINLIESKLGILDLLDEECKMPKGTDDTWAQKLYNTHLNKCALFEKP 541

Query: 570  KVVKGKAEAHFSLIHYAGTVDYNITGWLDKNKDPLNDTVVGLYQKSAMKTLASLFSTYAS 629
            ++    +   F + H+A  V+Y   G+L+KNKD + +  + + + S  K L  LF     
Sbjct: 542  RL----SNKAFIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLPELFQDDEK 597

Query: 630  AEADSSAKKGAKK----------KGSSFQ-------TVSALFRENLNKLMTNLRSTHPHF 672
            A + +SA    +           KG   Q       TV   FR +L+ LM  L +T PH+
Sbjct: 598  AISPTSATSSGRTPLTRTPAKPTKGRPGQMAKEHKKTVGHQFRNSLHLLMETLNATTPHY 657

Query: 673  VRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYGDFKQRYKVLNASA 732
            VRCI PN+ K P   + +  + QLR  GVLE IRI   GFPSR  Y +F  RY+VL    
Sbjct: 658  VRCIKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRVLMKQ- 716

Query: 733  IPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDEKLAQIITRTQ 792
              +    D K+  + +L  + +D  +Y+FG TK+FF+AG +  LE++R +KL     R Q
Sbjct: 717  --KDVLSDRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKLRADKLRAACIRIQ 774

Query: 793  AVCRGFLMRVEYQKMLQRREALFCIQYNVRAFM---------NVKHWPWMKLFFKIKPLL 843
               RG+L+R +Y +M   R+A   +Q  VR +            K    ++ ++++  + 
Sbjct: 775  KTIRGWLLRKKYLRM---RKAAITMQRYVRGYQARCYAKFLRRTKAATIIQKYWRMYVVR 831

Query: 844  KSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLAD 903
            +  +  +    + + +   +  LA++  ++   E K V + K       +   +    A 
Sbjct: 832  RRYKIRRAATIVLQSY--LRGFLARNRYRKILREHKAVIIQKRVRGWLARTHYKRSMHAI 889

Query: 904  AEERC---EQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDL 960
               +C     + K +++   K+K      E  ++++  +  K  +L+ +  E  KD   L
Sbjct: 890  IYLQCCFRRMMAKRELK---KLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCL 946

Query: 961  ELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDKV 1020
               L  +E   ++   K+++  E +   +E     +    +LQE   +   DL+    + 
Sbjct: 947  VEKLTNLEGIYNSETEKLRSDLERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEK 1006

Query: 1021 NILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDL-KLAQESTMDME----ND 1075
              + +   + +Q+ + L  +L++E  L   L++ K  L   + + A+E T  ME     +
Sbjct: 1007 KCIEEHADRYKQETEQLVSNLKEENTL---LKQEKEALNHRIVQQAKEMTETMEKKLVEE 1063

Query: 1076 KQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKA 1135
             +QL+  L  +     NL+++    +     L++++  L   + + G +      S  ++
Sbjct: 1064 TKQLELDLNDERLRYQNLLNEFSRLEERYDDLKEEM-TLMVHVPKPGHKRTDSTHSSNES 1122

Query: 1136 EKQRSDLSRELEEISERLEEAGGATSAQVELN-------KKREAEFQKLRRDLEEATLQH 1188
            E   S    E+E+I  R EE    +  +V L+       +KR  E ++ ++ +++   + 
Sbjct: 1123 EYIFSSEIAEMEDIPSRTEE---PSEKKVPLDMSLFLKLQKRVTELEQEKQVMQDELDRK 1179

Query: 1189 EAMVAALRKKHADSMAELGEQIDNLQRVKQKLEKEKSELKMETDDL------SSNAEAIS 1242
            E  V   + K  +     G +++     +Q+LE E  +LK E ++L       S  E  +
Sbjct: 1180 EEQVLRSKAKEEERPQIRGAELEYESLKRQELESENKKLKNELNELRKALSEKSAPEVTA 1239

Query: 1243 KAKGNLEKMCRSLEDQVSELKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVS 1302
                    +   L     EL  ++EE   L + L +Q+  +Q +        D+K+ +  
Sbjct: 1240 PGAPAYRVLMEQLTSVSEELDVRKEEVLILRSQLVSQKEAIQPK--------DDKNTMTD 1291

Query: 1303 QLSRSKQASTQQIEELKHQLE--EETKAKNALAHALQSSRHDCDLLREQYE--EEQEGKA 1358
                    ST  +E+++   +  E  +A   L    +SS  D   L E  E     EG  
Sbjct: 1292 --------STILLEDVQKMKDKGEIAQAYIGLKETNRSSALDYHELNEDGELWLVYEGLK 1343

Query: 1359 ELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKK-------LAQRLQ-EAEEHVEAV 1410
            +  R L    S++   +  +E +A     E++  K++       LAQ LQ   E  +E  
Sbjct: 1344 QANRLL---ESQLQSQKRSHENEAEALRGEIQSLKEENNRQQQLLAQNLQLPPEARIE-- 1398

Query: 1411 NAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQAEL 1470
                ASL+    RL NE  DLM  +E+ +     L K+ + F K +            EL
Sbjct: 1399 ----ASLQHEITRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKI-----------GEL 1443

Query: 1471 EASQKESRS---LSTELFKVKNVYEESLDQLETLRRENKNLQQEISDLTEQIAEGGKQIH 1527
            E  Q E+ S   +  E  +  N+  +  D    L  + ++ Q+ + +L  ++   G  ++
Sbjct: 1444 EVGQMENISPGQIIDEPIRPVNIPRKEKDFQGMLEYKKEDEQKLVKNLILELKPRGVAVN 1503



 Score = 76.3 bits (186), Expect = 3e-13
 Identities = 128/602 (21%), Positives = 251/602 (41%), Gaps = 86/602 (14%)

Query: 1314 QIEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEG-KAELQRA-LSKANSEV 1371
            +I +L+ +++E+ K    L   L +       L   Y  E E  +++L+R  LS+  ++V
Sbjct: 928  KIMQLQRKVDEQNKDYKCLVEKLTN-------LEGIYNSETEKLRSDLERLQLSEEEAKV 980

Query: 1372 AQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDL 1431
            A  R       +   EE+ + +K L Q   E          KC  +E+   R + E E L
Sbjct: 981  ATGRV------LSLQEEIAKLRKDLEQTRSEK---------KC--IEEHADRYKQETEQL 1023

Query: 1432 MLDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELFKVKNVY 1491
            + +++  N       +K+    +++ + K+  E  + +L    +E++ L  +L   +  Y
Sbjct: 1024 VSNLKEENTLLK--QEKEALNHRIVQQAKEMTETMEKKLV---EETKQLELDLNDERLRY 1078

Query: 1492 EESLDQLETLRRENKNLQQEISDLTEQIAEGGKQI------HELEKIKKQVEQEKCEIQA 1545
            +  L++   L     +L++E++ +      G K+       +E E I      E  +I +
Sbjct: 1079 QNLLNEFSRLEERYDDLKEEMTLMVHVPKPGHKRTDSTHSSNESEYIFSSEIAEMEDIPS 1138

Query: 1546 ALEE-AEASLEHEEGKILRIQ---LELNQVKSEVDRKIAEKDEEIDQLKRNHTRVVETMQ 1601
              EE +E  +  +    L++Q    EL Q K  +  ++  K+E++ + K       +   
Sbjct: 1139 RTEEPSEKKVPLDMSLFLKLQKRVTELEQEKQVMQDELDRKEEQVLRSKAKEEERPQIRG 1198

Query: 1602 STLDAEIRSRNDALRVKKKMEGDLNEMEIQLNH------------ANRLAAESLRNYRNT 1649
            + L+ E   R +     KK++ +LNE+   L+             A R+  E L +    
Sbjct: 1199 AELEYESLKRQELESENKKLKNELNELRKALSEKSAPEVTAPGAPAYRVLMEQLTSVSEE 1258

Query: 1650 QGILKETQLHLDDALRGQEDL---KEQLAIVERRANLLQ--------AEIEELWATLEQT 1698
              + KE  L L   L  Q++    K+    +     LL+         EI + +  L++T
Sbjct: 1259 LDVRKEEVLILRSQLVSQKEAIQPKDDKNTMTDSTILLEDVQKMKDKGEIAQAYIGLKET 1318

Query: 1699 ERSRKIAEQELLDASE-------RVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQES 1751
             RS  +   EL +  E         Q      + L + K+  EN+   L+ E++ + +E+
Sbjct: 1319 NRSSALDYHELNEDGELWLVYEGLKQANRLLESQLQSQKRSHENEAEALRGEIQSLKEEN 1378

Query: 1752 RNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGG 1811
               ++   + +        +L  E    A L+     L     DL  +L++ ++   K  
Sbjct: 1379 NRQQQLLAQNL--------QLPPEARIEASLQHEITRLTNENLDLMEQLEKQDKTVRK-L 1429

Query: 1812 KKQIQKLEARVRELE-GEVENEQKRNA--EAVKGL---RKHERRVKELTYQTEEDRKNVL 1865
            KKQ++    ++ ELE G++EN        E ++ +   RK +     L Y+ E+++K V 
Sbjct: 1430 KKQLKVFAKKIGELEVGQMENISPGQIIDEPIRPVNIPRKEKDFQGMLEYKKEDEQKLVK 1489

Query: 1866 RL 1867
             L
Sbjct: 1490 NL 1491



 Score = 54.3 bits (129), Expect = 1e-06
 Identities = 89/407 (21%), Positives = 172/407 (42%), Gaps = 79/407 (19%)

Query: 1463 YEETQAELEASQKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEISDLTEQIAE- 1521
            +    A+ E  + +  + S E +K  ++  E+  ++  L+R+     ++   L E++   
Sbjct: 896  FRRMMAKRELKKLKIEARSVERYKKLHIGMEN--KIMQLQRKVDEQNKDYKCLVEKLTNL 953

Query: 1522 GGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAE 1581
             G    E EK++  +E+    +Q + EEA+ +     G++L +Q E+ +++ ++++  +E
Sbjct: 954  EGIYNSETEKLRSDLER----LQLSEEEAKVAT----GRVLSLQEEIAKLRKDLEQTRSE 1005

Query: 1582 K---DEEIDQLKRNHTRVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEMEIQLNHANRL 1638
            K   +E  D+ K+   ++V        + ++  N  L+ +K+           LNH    
Sbjct: 1006 KKCIEEHADRYKQETEQLV--------SNLKEENTLLKQEKEA----------LNHRIVQ 1047

Query: 1639 AAESLRNYRNTQGILKETQLHLD---DALRGQEDLKEQLAIVERRANLLQAEIEELWATL 1695
             A+ +      + + +  QL LD   + LR Q  L E   + ER  +L     EE+   +
Sbjct: 1048 QAKEMTETMEKKLVEETKQLELDLNDERLRYQNLLNEFSRLEERYDDLK----EEMTLMV 1103

Query: 1696 EQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQESRNAE 1755
               +   K           R    H+ N S        E   S   +E+E++   SR  E
Sbjct: 1104 HVPKPGHK-----------RTDSTHSSNES--------EYIFSSEIAEMEDI--PSRTEE 1142

Query: 1756 EKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQI 1815
               KK   D ++  +           L++    LEQ  + +Q  LD  E+  L+   K+ 
Sbjct: 1143 PSEKKVPLDMSLFLK-----------LQKRVTELEQEKQVMQDELDRKEEQVLRSKAKEE 1191

Query: 1816 QKLEARVRELE------GEVENEQKRNAEAVKGLRK--HERRVKELT 1854
            ++ + R  ELE       E+E+E K+    +  LRK   E+   E+T
Sbjct: 1192 ERPQIRGAELEYESLKRQELESENKKLKNELNELRKALSEKSAPEVT 1238



 Score = 54.3 bits (129), Expect = 1e-06
 Identities = 73/338 (21%), Positives = 135/338 (39%), Gaps = 36/338 (10%)

Query: 1604 LDAEIRSRNDALRVKKKMEGDLNEMEIQLNHANRLAAESLRNYRNTQGILKETQLHLDDA 1663
            L  E RS     ++   ME  + +++ +++  N+     +    N +GI       L   
Sbjct: 908  LKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNSETEKLRSD 967

Query: 1664 LRGQEDLKEQLAIVERRANLLQAEIEELWATLEQTERSRKIAEQEL----LDASERVQLL 1719
            L   +  +E+  +   R   LQ EI +L   LEQT   +K  E+       +  + V  L
Sbjct: 968  LERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKCIEEHADRYKQETEQLVSNL 1027

Query: 1720 HTQNTSLINTKKKLENDVSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTS 1779
              +NT L   K+ L + + Q   E+ E ++         KK + +   +  +L  E+   
Sbjct: 1028 KEENTLLKQEKEALNHRIVQQAKEMTETME---------KKLVEETKQLELDLNDERLRY 1078

Query: 1780 AHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQK---------LEARVRELEG--- 1827
             +L      LE+   DL+  +     +   G K+               + + E+E    
Sbjct: 1079 QNLLNEFSRLEERYDDLKEEMTLMVHVPKPGHKRTDSTHSSNESEYIFSSEIAEMEDIPS 1138

Query: 1828 -EVENEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQAKVKSYKRQAE 1886
               E  +K+    +    K ++RV EL     E  K V+  QD +D+ + +V   K + E
Sbjct: 1139 RTEEPSEKKVPLDMSLFLKLQKRVTEL-----EQEKQVM--QDELDRKEEQVLRSKAKEE 1191

Query: 1887 EAEEQSNANLSKFRKLQHELEEAEERADIAESQVNKLR 1924
            E  +   A L      + ELE   ++    ++++N+LR
Sbjct: 1192 ERPQIRGAELEYESLKRQELESENKK---LKNELNELR 1226



 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 103/564 (18%), Positives = 220/564 (39%), Gaps = 134/564 (23%)

Query: 1460 KQKYEETQAELEASQKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEISDLTEQI 1519
            + K  + Q +++   K+ + L  +L  ++ +Y     + E LR + + LQ  +S+   ++
Sbjct: 926  ENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNS---ETEKLRSDLERLQ--LSEEEAKV 980

Query: 1520 AEGG--KQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEVDR 1577
            A G       E+ K++K +EQ + E +   E A+                  + K E ++
Sbjct: 981  ATGRVLSLQEEIAKLRKDLEQTRSEKKCIEEHAD------------------RYKQETEQ 1022

Query: 1578 KIAEKDEEIDQLKR-----NHTRVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEMEIQ- 1631
             ++   EE   LK+     NH  V +  + T   E       +   K++E DLN+  ++ 
Sbjct: 1023 LVSNLKEENTLLKQEKEALNHRIVQQAKEMTETME----KKLVEETKQLELDLNDERLRY 1078

Query: 1632 ---LNHANRL-----------------------AAESLRNYRNTQGILKETQLHLDDALR 1665
               LN  +RL                         +S  +   ++ I       ++D   
Sbjct: 1079 QNLLNEFSRLEERYDDLKEEMTLMVHVPKPGHKRTDSTHSSNESEYIFSSEIAEMEDIPS 1138

Query: 1666 GQED---------------LKEQLAIVERRANLLQAEI----EELWATLEQTERSRKIAE 1706
              E+               L++++  +E+   ++Q E+    E++  +  + E   +I  
Sbjct: 1139 RTEEPSEKKVPLDMSLFLKLQKRVTELEQEKQVMQDELDRKEEQVLRSKAKEEERPQIRG 1198

Query: 1707 QELLDASERVQLLHTQNTSLINTKKKLENDVS--------------------QLQSEVEE 1746
             EL   S + Q L ++N  L N   +L   +S                    QL S  EE
Sbjct: 1199 AELEYESLKRQELESENKKLKNELNELRKALSEKSAPEVTAPGAPAYRVLMEQLTSVSEE 1258

Query: 1747 ---------------VIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLER---MKKN 1788
                           V Q+     +  K  +TD+ ++ E+++K +D     +    +K+ 
Sbjct: 1259 LDVRKEEVLILRSQLVSQKEAIQPKDDKNTMTDSTILLEDVQKMKDKGEIAQAYIGLKET 1318

Query: 1789 LEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHER 1848
               +  D     ++ E   +  G KQ  +L      LE +++++++ +    + LR   +
Sbjct: 1319 NRSSALDYHELNEDGELWLVYEGLKQANRL------LESQLQSQKRSHENEAEALRGEIQ 1372

Query: 1849 RVKELTYQTEEDRKNVLRLQDLVDKLQAKVKSYKRQAEEAEEQSNANLSKFRKLQHE--- 1905
             +KE     E +R+  L  Q+L    +A++++  +   E    +N NL    +L+ +   
Sbjct: 1373 SLKE-----ENNRQQQLLAQNLQLPPEARIEASLQ--HEITRLTNENLDLMEQLEKQDKT 1425

Query: 1906 LEEAEERADIAESQVNKLRVKSRE 1929
            + + +++  +   ++ +L V   E
Sbjct: 1426 VRKLKKQLKVFAKKIGELEVGQME 1449


>gi|215982794 myosin VA isoform 2 [Homo sapiens]
          Length = 1828

 Score =  590 bits (1521), Expect = e-168
 Identities = 448/1549 (28%), Positives = 753/1549 (48%), Gaps = 146/1549 (9%)

Query: 40   VFVAEPKESYVKSTIQS--KEGGKVTV-KTEGGATLTVRED---QVFP--MNPPKYDKIE 91
            V++ +P+E +  + +    K G KV +   E G  L    D   +  P   NP       
Sbjct: 13   VWIPDPEEVWKSAELLKDYKPGDKVLLLHLEEGKDLEYHLDPKTKELPHLRNPDILVGEN 72

Query: 92   DMAMMTHLHEPGVLYNLKERYA-AWMIYTYSGLFCVTVNPYKWLPVYKPEVVAAYRGKKR 150
            D+  +++LHEP VL+NL+ R+  + +IYTY G+  V +NPY+ LP+Y  +++ AY G+  
Sbjct: 73   DLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAYSGQNM 132

Query: 151  QEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKD 210
             +  PHIF++++ AY+ M  D  NQSI+++GESGAGKTV+ K  ++YFAT++ +      
Sbjct: 133  GDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGSAS---- 188

Query: 211  ESGKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYL 270
                 +  +E++++++NP++E+ GNAKT RNDNSSRFGK+I I F    ++  A++ TYL
Sbjct: 189  -----EANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMRTYL 243

Query: 271  LEKSRVTFQLKAERSYHIFYQITSNKKPDLIEMLLITTNPYDYAFVSQG-EITVPSIDDQ 329
            LEKSRV FQ + ER+YHIFYQ+ ++ K    +ML +  N  ++ +  QG    +  +DD 
Sbjct: 244  LEKSRVVFQAEEERNYHIFYQLCASAKLPEFKMLRLG-NADNFNYTKQGGSPVIEGVDDA 302

Query: 330  EELMATDSAIDILGFTPEEKVSIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKAAY 389
            +E+  T  A  +LG +   ++ I+++   ++H GN+ F  +  +    P   E       
Sbjct: 303  KEMAHTRQACTLLGISESHQMGIFRILAGILHLGNVGFTSRDADSCTIPPKHEPLCIFCD 362

Query: 390  LQSLNSADLLKALCYPRVKVGNEYVTKGQTVQQVYNAVGALAKAVYEKMFLWMVTRINQQ 449
            L  ++  ++   LC+ ++    E   K  +  Q  NA  ALAK +Y K+F W+V  +NQ 
Sbjct: 363  LMGVDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVDNVNQA 422

Query: 450  LDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGI 509
            L +   +  FIGVLDI GFE F+ NS EQ CIN+ NEKLQQ FN H+F LEQEEY KE I
Sbjct: 423  LHSAVKQHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEQI 482

Query: 510  EWTFIDFGMDLAACIELIEKPLGIFSILEEECMFPKATDTSFKNKLYDQHLGKSANFQKP 569
             WT IDF  D   CI LIE  LGI  +L+EEC  PK TD ++  KLY+ HL K A F+KP
Sbjct: 483  PWTLIDF-YDNQPCINLIESKLGILDLLDEECKMPKGTDDTWAQKLYNTHLNKCALFEKP 541

Query: 570  KVVKGKAEAHFSLIHYAGTVDYNITGWLDKNKDPLNDTVVGLYQKSAMKTLASLFSTYAS 629
            ++    +   F + H+A  V+Y   G+L+KNKD + +  + + + S  K L  LF     
Sbjct: 542  RL----SNKAFIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLPELFQDDEK 597

Query: 630  AEADSSAKKGAKK----------KGSSFQ-------TVSALFRENLNKLMTNLRSTHPHF 672
            A + +SA    +           KG   Q       TV   FR +L+ LM  L +T PH+
Sbjct: 598  AISPTSATSSGRTPLTRTPAKPTKGRPGQMAKEHKKTVGHQFRNSLHLLMETLNATTPHY 657

Query: 673  VRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYGDFKQRYKVLNASA 732
            VRCI PN+ K P   + +  + QLR  GVLE IRI   GFPSR  Y +F  RY+VL    
Sbjct: 658  VRCIKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRVLMKQ- 716

Query: 733  IPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDEKLAQIITRTQ 792
              +    D K+  + +L  + +D  +Y+FG TK+FF+AG +  LE++R +KL     R Q
Sbjct: 717  --KDVLSDRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKLRADKLRAACIRIQ 774

Query: 793  AVCRGFLMRVEYQKMLQRREALFCIQYNVRAFM---------NVKHWPWMKLFFKIKPLL 843
               RG+L+R +Y +M   R+A   +Q  VR +            K    ++ ++++  + 
Sbjct: 775  KTIRGWLLRKKYLRM---RKAAITMQRYVRGYQARCYAKFLRRTKAATIIQKYWRMYVVR 831

Query: 844  KSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLAD 903
            +  +  +    + + +   +  LA++  ++   E K V + K       +   +    A 
Sbjct: 832  RRYKIRRAATIVLQSY--LRGFLARNRYRKILREHKAVIIQKRVRGWLARTHYKRSMHAI 889

Query: 904  AEERC---EQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDL 960
               +C     + K +++   K+K      E  ++++  +  K  +L+ +  E  KD   L
Sbjct: 890  IYLQCCFRRMMAKRELK---KLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCL 946

Query: 961  ELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDKV 1020
               L  +E   ++   K+++  E +   +E     +    +LQE   +   DL+    + 
Sbjct: 947  VEKLTNLEGIYNSETEKLRSDLERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEK 1006

Query: 1021 NILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDL-KLAQESTMDME----ND 1075
              + +   + +Q+ + L  +L++E  L   L++ K  L   + + A+E T  ME     +
Sbjct: 1007 KCIEEHADRYKQETEQLVSNLKEENTL---LKQEKEALNHRIVQQAKEMTETMEKKLVEE 1063

Query: 1076 KQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKA 1135
             +QL+  L  +     NL+++    +     L++++  L   + + G +      S  ++
Sbjct: 1064 TKQLELDLNDERLRYQNLLNEFSRLEERYDDLKEEM-TLMVHVPKPGHKRTDSTHSSNES 1122

Query: 1136 EKQRSDLSRELEEISERLEEAGGATSAQVELN-------KKREAEFQKLRRDLEEATLQH 1188
            E   S    E+E+I  R EE    +  +V L+       +KR  E ++ ++ +++   + 
Sbjct: 1123 EYIFSSEIAEMEDIPSRTEE---PSEKKVPLDMSLFLKLQKRVTELEQEKQVMQDELDRK 1179

Query: 1189 EAMVAALRKKHADSMAELGEQIDNLQRVKQKLEKEKSELKMETDDL------SSNAEAIS 1242
            E  V   + K  +     G +++     +Q+LE E  +LK E ++L       S  E  +
Sbjct: 1180 EEQVLRSKAKEEERPQIRGAELEYESLKRQELESENKKLKNELNELRKALSEKSAPEVTA 1239

Query: 1243 KAKGNLEKMCRSLEDQVSELKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVS 1302
                    +   L     EL  ++EE   L + L +Q+  +Q +        D+K+ +  
Sbjct: 1240 PGAPAYRVLMEQLTSVSEELDVRKEEVLILRSQLVSQKEAIQPK--------DDKNTMTD 1291

Query: 1303 QLSRSKQASTQQIEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQR 1362
                    ST  +E++     ++ K K  +A A    +    LL  Q + ++        
Sbjct: 1292 --------STILLEDV-----QKMKDKGEIAQAYIGLKETNRLLESQLQSQKRSHENEAE 1338

Query: 1363 ALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQ-EAEEHVEAVNAKCASLEKTK 1421
            AL     E+   +           EE    ++ LAQ LQ   E  +E      ASL+   
Sbjct: 1339 AL---RGEIQSLK-----------EENNRQQQLLAQNLQLPPEARIE------ASLQHEI 1378

Query: 1422 QRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQAELEASQKESRS-- 1479
             RL NE  DLM  +E+ +     L K+ + F K +            ELE  Q E+ S  
Sbjct: 1379 TRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKI-----------GELEVGQMENISPG 1427

Query: 1480 -LSTELFKVKNVYEESLDQLETLRRENKNLQQEISDLTEQIAEGGKQIH 1527
             +  E  +  N+  +  D    L  + ++ Q+ + +L  ++   G  ++
Sbjct: 1428 QIIDEPIRPVNIPRKEKDFQGMLEYKKEDEQKLVKNLILELKPRGVAVN 1476



 Score = 75.5 bits (184), Expect = 5e-13
 Identities = 126/586 (21%), Positives = 248/586 (42%), Gaps = 81/586 (13%)

Query: 1314 QIEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEG-KAELQRA-LSKANSEV 1371
            +I +L+ +++E+ K    L   L +       L   Y  E E  +++L+R  LS+  ++V
Sbjct: 928  KIMQLQRKVDEQNKDYKCLVEKLTN-------LEGIYNSETEKLRSDLERLQLSEEEAKV 980

Query: 1372 AQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDL 1431
            A  R       +   EE+ + +K L Q   E          KC  +E+   R + E E L
Sbjct: 981  ATGRV------LSLQEEIAKLRKDLEQTRSEK---------KC--IEEHADRYKQETEQL 1023

Query: 1432 MLDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELFKVKNVY 1491
            + +++  N       +K+    +++ + K+  E  + +L    +E++ L  +L   +  Y
Sbjct: 1024 VSNLKEENTLLK--QEKEALNHRIVQQAKEMTETMEKKLV---EETKQLELDLNDERLRY 1078

Query: 1492 EESLDQLETLRRENKNLQQEISDLTEQIAEGGKQI------HELEKIKKQVEQEKCEIQA 1545
            +  L++   L     +L++E++ +      G K+       +E E I      E  +I +
Sbjct: 1079 QNLLNEFSRLEERYDDLKEEMTLMVHVPKPGHKRTDSTHSSNESEYIFSSEIAEMEDIPS 1138

Query: 1546 ALEE-AEASLEHEEGKILRIQ---LELNQVKSEVDRKIAEKDEEIDQLKRNHTRVVETMQ 1601
              EE +E  +  +    L++Q    EL Q K  +  ++  K+E++ + K       +   
Sbjct: 1139 RTEEPSEKKVPLDMSLFLKLQKRVTELEQEKQVMQDELDRKEEQVLRSKAKEEERPQIRG 1198

Query: 1602 STLDAEIRSRNDALRVKKKMEGDLNEMEIQLNH------------ANRLAAESLRNYRNT 1649
            + L+ E   R +     KK++ +LNE+   L+             A R+  E L +    
Sbjct: 1199 AELEYESLKRQELESENKKLKNELNELRKALSEKSAPEVTAPGAPAYRVLMEQLTSVSEE 1258

Query: 1650 QGILKETQLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELWATLEQTERSRKIAE--Q 1707
              + KE  L L   L  Q   KE +   + +  +  + I      LE  ++ +   E  Q
Sbjct: 1259 LDVRKEEVLILRSQLVSQ---KEAIQPKDDKNTMTDSTI-----LLEDVQKMKDKGEIAQ 1310

Query: 1708 ELLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQESRNAEEKAKKAITDAAM 1767
              +   E  +LL +Q   L + K+  EN+   L+ E++ + +E+   ++   + +     
Sbjct: 1311 AYIGLKETNRLLESQ---LQSQKRSHENEAEALRGEIQSLKEENNRQQQLLAQNL----- 1362

Query: 1768 MAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELE- 1826
               +L  E    A L+     L     DL  +L++ ++   K  KKQ++    ++ ELE 
Sbjct: 1363 ---QLPPEARIEASLQHEITRLTNENLDLMEQLEKQDKTVRK-LKKQLKVFAKKIGELEV 1418

Query: 1827 GEVENEQKRNA--EAVKGL---RKHERRVKELTYQTEEDRKNVLRL 1867
            G++EN        E ++ +   RK +     L Y+ E+++K V  L
Sbjct: 1419 GQMENISPGQIIDEPIRPVNIPRKEKDFQGMLEYKKEDEQKLVKNL 1464



 Score = 54.3 bits (129), Expect = 1e-06
 Identities = 89/407 (21%), Positives = 172/407 (42%), Gaps = 79/407 (19%)

Query: 1463 YEETQAELEASQKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEISDLTEQIAE- 1521
            +    A+ E  + +  + S E +K  ++  E+  ++  L+R+     ++   L E++   
Sbjct: 896  FRRMMAKRELKKLKIEARSVERYKKLHIGMEN--KIMQLQRKVDEQNKDYKCLVEKLTNL 953

Query: 1522 GGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAE 1581
             G    E EK++  +E+    +Q + EEA+ +     G++L +Q E+ +++ ++++  +E
Sbjct: 954  EGIYNSETEKLRSDLER----LQLSEEEAKVAT----GRVLSLQEEIAKLRKDLEQTRSE 1005

Query: 1582 K---DEEIDQLKRNHTRVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEMEIQLNHANRL 1638
            K   +E  D+ K+   ++V        + ++  N  L+ +K+           LNH    
Sbjct: 1006 KKCIEEHADRYKQETEQLV--------SNLKEENTLLKQEKEA----------LNHRIVQ 1047

Query: 1639 AAESLRNYRNTQGILKETQLHLD---DALRGQEDLKEQLAIVERRANLLQAEIEELWATL 1695
             A+ +      + + +  QL LD   + LR Q  L E   + ER  +L     EE+   +
Sbjct: 1048 QAKEMTETMEKKLVEETKQLELDLNDERLRYQNLLNEFSRLEERYDDLK----EEMTLMV 1103

Query: 1696 EQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQESRNAE 1755
               +   K           R    H+ N S        E   S   +E+E++   SR  E
Sbjct: 1104 HVPKPGHK-----------RTDSTHSSNES--------EYIFSSEIAEMEDI--PSRTEE 1142

Query: 1756 EKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQI 1815
               KK   D ++  +           L++    LEQ  + +Q  LD  E+  L+   K+ 
Sbjct: 1143 PSEKKVPLDMSLFLK-----------LQKRVTELEQEKQVMQDELDRKEEQVLRSKAKEE 1191

Query: 1816 QKLEARVRELE------GEVENEQKRNAEAVKGLRK--HERRVKELT 1854
            ++ + R  ELE       E+E+E K+    +  LRK   E+   E+T
Sbjct: 1192 ERPQIRGAELEYESLKRQELESENKKLKNELNELRKALSEKSAPEVT 1238



 Score = 49.3 bits (116), Expect = 4e-05
 Identities = 99/489 (20%), Positives = 196/489 (40%), Gaps = 90/489 (18%)

Query: 1460 KQKYEETQAELEASQKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEISDLTEQI 1519
            + K  + Q +++   K+ + L  +L  ++ +Y     + E LR + + LQ  +S+   ++
Sbjct: 926  ENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNS---ETEKLRSDLERLQ--LSEEEAKV 980

Query: 1520 AEGG--KQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEVDR 1577
            A G       E+ K++K +EQ + E +   E A+                  + K E ++
Sbjct: 981  ATGRVLSLQEEIAKLRKDLEQTRSEKKCIEEHAD------------------RYKQETEQ 1022

Query: 1578 KIAEKDEEIDQLKRNHTRVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEMEIQLNHANR 1637
             ++   EE   LK+      E +   +  + +   + +  +KK+  +  ++E+ LN    
Sbjct: 1023 LVSNLKEENTLLKQEK----EALNHRIVQQAKEMTETM--EKKLVEETKQLELDLND--- 1073

Query: 1638 LAAESLRNYRNTQGILKETQLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELWATLEQ 1697
               E LR Y+N        +   D       DLKE++ ++          +       ++
Sbjct: 1074 ---ERLR-YQNLLNEFSRLEERYD-------DLKEEMTLM----------VHVPKPGHKR 1112

Query: 1698 TERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVS---QLQSEVEEVIQESR-- 1752
            T+ +    E E + +SE  ++    + +   ++KK+  D+S   +LQ  V E+ QE +  
Sbjct: 1113 TDSTHSSNESEYIFSSEIAEMEDIPSRTEEPSEKKVPLDMSLFLKLQKRVTELEQEKQVM 1172

Query: 1753 --------------NAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQH 1798
                           A+E+ +  I  A +  E LK+++     LE   K L+  + +L+ 
Sbjct: 1173 QDELDRKEEQVLRSKAKEEERPQIRGAELEYESLKRQE-----LESENKKLKNELNELRK 1227

Query: 1799 RLDE--AEQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHERRVKELTYQ 1856
             L E  A ++   G       +E         V  E     E V  LR      KE   Q
Sbjct: 1228 ALSEKSAPEVTAPGAPAYRVLMEQLT-----SVSEELDVRKEEVLILRSQLVSQKE-AIQ 1281

Query: 1857 TEEDRKNVLRLQDLVDKLQ-AKVKSYKRQAEEAEEQSNANLSKFRKLQHELEEAEERADI 1915
             ++D+  +     L++ +Q  K K    QA    +++N  L    +LQ +    E  A+ 
Sbjct: 1282 PKDDKNTMTDSTILLEDVQKMKDKGEIAQAYIGLKETNRLLES--QLQSQKRSHENEAEA 1339

Query: 1916 AESQVNKLR 1924
               ++  L+
Sbjct: 1340 LRGEIQSLK 1348


>gi|122937345 myosin VB [Homo sapiens]
          Length = 1848

 Score =  575 bits (1481), Expect = e-163
 Identities = 463/1593 (29%), Positives = 775/1593 (48%), Gaps = 166/1593 (10%)

Query: 38   TSVFVAEPKESY--VKSTIQSKEGGK-VTVKTEGGATLT----VREDQV-FPMNPPKYDK 89
            T V++ +P E +   + T   KEG K + ++ E    L     V+ +Q+ F  NP     
Sbjct: 11   TRVWIPDPDEVWRSAELTKDYKEGDKSLQLRLEDETILEYPIDVQRNQLPFLRNPDILVG 70

Query: 90   IEDMAMMTHLHEPGVLYNLKERYA-AWMIYTYSGLFCVTVNPYKWLPVYKPEVVAAYRGK 148
              D+  +++LHEP VL+NLK R+  +  IYTY G+  V +NPY+ LP+Y  +V+  Y G+
Sbjct: 71   ENDLTALSYLHEPAVLHNLKVRFLESNHIYTYCGIVLVAINPYEQLPIYGQDVIYTYSGQ 130

Query: 149  KRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKK 208
               +  PHIF++++ AY+ M  D +NQSI+++GESGAGKTV+ K  ++YFAT+  +  + 
Sbjct: 131  NMGDMDPHIFAVAEEAYKQMARDEKNQSIIVSGESGAGKTVSAKYAMRYFATVGGSASET 190

Query: 209  KDESGKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIET 268
                      +E+++++++P++EA GNAKT RNDNSSRFGK+I+I F     +  A++ T
Sbjct: 191  N---------IEEKVLASSPIMEAIGNAKTTRNDNSSRFGKYIQIGFDKRYHIIGANMRT 241

Query: 269  YLLEKSRVTFQLKAERSYHIFYQITSNKK-PDLIEMLLITTNPYDYAFVSQG-EITVPSI 326
            YLLEKSRV FQ   ER+YHIFYQ+ +    P+  E+ L  T+  D+ + SQG + ++  +
Sbjct: 242  YLLEKSRVVFQADDERNYHIFYQLCAAAGLPEFKELAL--TSAEDFFYTSQGGDTSIEGV 299

Query: 327  DDQEELMATDSAIDILGFTPEEKVSIYKLTGAVMHYGNMKFKQKQREEQAEPDGTE--VA 384
            DD E+   T  A  +LG     ++SI+K+  +++H G++         QAE DG    ++
Sbjct: 300  DDAEDFEKTRQAFTLLGVKESHQMSIFKIIASILHLGSVAI-------QAERDGDSCSIS 352

Query: 385  DKAAYLQS------LNSADLLKALCYPRVKVGNEYVTKGQTVQQVYNAVGALAKAVYEKM 438
             +  YL +      +  + +   LC+ ++   +E   K  ++QQV NA  ALAK +Y ++
Sbjct: 353  PQDVYLSNFCRLLGVEHSQMEHWLCHRKLVTTSETYVKTMSLQQVINARNALAKHIYAQL 412

Query: 439  FLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFV 498
            F W+V  IN+ L T   +  FIGVLDI GFE F+ NS EQ CIN+ NEKLQQ FN H+F 
Sbjct: 413  FGWIVEHINKALHTSLKQHSFIGVLDIYGFETFEVNSFEQFCINYANEKLQQQFNSHVFK 472

Query: 499  LEQEEYKKEGIEWTFIDFGMDLAACIELIEKPLGIFSILEEECMFPKATDTSFKNKLYDQ 558
            LEQEEY KE I WT IDF  D   CI+LIE  LGI  +L+EEC  PK TD ++  KLYD+
Sbjct: 473  LEQEEYMKEQIPWTLIDF-YDNQPCIDLIEAKLGILDLLDEECKVPKGTDQNWAQKLYDR 531

Query: 559  HLGKSANFQKPKVVKGKAEAHFSLIHYAGTVDYNITGWLDKNKDPLNDTVVGLYQKSAMK 618
            H   S +FQKP++    +   F ++H+A  V+Y   G+L+KN+D + +  + + + S   
Sbjct: 532  H-SSSQHFQKPRM----SNTAFIIVHFADKVEYLSDGFLEKNRDTVYEEQINILKASKFP 586

Query: 619  TLASLFSTYASAEADSSAKKGAKKKGS--------------SFQTVSALFRENLNKLMTN 664
             +A LF         ++  KG+  K S                +TV   FR +L+ LM  
Sbjct: 587  LVADLFHDDKDPVPATTPGKGSSSKISVRSARPPMKVSNKEHKKTVGHQFRTSLHLLMET 646

Query: 665  LRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYGDFKQR 724
            L +T PH+VRCI PN+ K P   + +  + QLR  GVLE IRI   G+PSR  Y DF  R
Sbjct: 647  LNATTPHYVRCIKPNDEKLPFHFDPKRAVQQLRACGVLETIRISAAGYPSRWAYHDFFNR 706

Query: 725  YKVLNASAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDEKL 784
            Y+VL      E    D K     +L ++  D  +++FG TK+FF+AG +  LE++R +K 
Sbjct: 707  YRVLVKKR--ELANTDKKAICRSVLENLIKDPDKFQFGRTKIFFRAGQVAYLEKLRADKF 764

Query: 785  AQIITRTQAVCRGFLMRVEYQKM------LQRREALFCIQYNVRAFMNVKHWPWMKLFFK 838
                   Q   RG+L +V+Y ++      LQR       +        ++    ++  ++
Sbjct: 765  RTATIMIQKTVRGWLQKVKYHRLKGATLTLQRYCRGHLARRLAEHLRRIRAAVVLQKHYR 824

Query: 839  IKPLLKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEA 898
            ++   ++ +  +  A + + F  T+    +   ++  +E K  T+ K       +   + 
Sbjct: 825  MQRARQAYQRVRRAAVVIQAF--TRAMFVRRTYRQVLMEHKATTIQKHVRGWMARRHFQR 882

Query: 899  DSLADAEERCE-QLIKNKIQLEAKIKEVTERAEEEEEINAELTAK----KRKLEDECSEL 953
               A    +C  +++K + +L+A ++     AE  + +N  +  K    +RK++++  E 
Sbjct: 883  LRDAAIVIQCAFRMLKARRELKA-LRIEARSAEHLKRLNVGMENKVVQLQRKIDEQNKEF 941

Query: 954  KKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDL 1013
            K   + L +T +    E       V+ L +E+    ++  + +  +  LQE  +    +L
Sbjct: 942  KTLSEQLSVTTSTYTME-------VERLKKELVHYQQSPGEDTSLR--LQEEVESLRTEL 992

Query: 1014 QAEEDKVNILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDME 1073
            Q    +  IL  A ++ + ++      LEQE  L   L+  K +L   + L Q      +
Sbjct: 993  QRAHSERKILEDAHSREKDELRKRVADLEQENAL---LKDEKEQLNNQI-LCQSKDEFAQ 1048

Query: 1074 NDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEE--IEAERAS 1131
            N    + E L KKE         +E+E++    L K+  +L+ R + L +E  I  +   
Sbjct: 1049 N---SVKENLMKKE---------LEEERSRYQNLVKEYSQLEQRYDNLRDEMTIIKQTPG 1096

Query: 1132 RAKAEKQRSDLSRELEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQHEAM 1191
              +    +S L  +    S    E G    A                + +EE  L+  AM
Sbjct: 1097 HRRNPSNQSSLESDSNYPSISTSEIGDTEDA---------------LQQVEEIGLEKAAM 1141

Query: 1192 VAALRKKHADSMAELGEQIDNLQ-----RVKQKLEKEKSELKMETDDLSSNAEAISKAKG 1246
               +  K    + EL ++   LQ     R +Q  +K ++E      DL  NA+    A  
Sbjct: 1142 DMTVFLKLQKRVRELEQERKKLQVQLEKREQQDSKKVQAEPPQTDIDLDPNADL---AYN 1198

Query: 1247 NLEKMCRSLEDQVSELKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQLSR 1306
            +L++  + LE +  +LK    E ++ + D   Q          YS  L++      +L  
Sbjct: 1199 SLKR--QELESENKKLKNDLNELRKAVADQATQNNSSHGSPDSYSLLLNQLKLAHEELEV 1256

Query: 1307 SKQASTQQIEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSK 1366
             K    +++  L+ Q+    + + A  +A  +          +   +QE   E    + +
Sbjct: 1257 RK----EEVLILRTQIVSADQRRLAGRNAEPNINARSSWPNSEKHVDQEDAIEAYHGVCQ 1312

Query: 1367 ANSEVAQWRTKYETDAIQRT-EELEEAKKKLAQRLQ-EAEEHVEAVNAKCASLEKTKQRL 1424
             NS+   W    E   +    + L++  + L  +LQ ++ EH E V    A LE  K+  
Sbjct: 1313 TNSKTEDWGYLNEDGELGLAYQGLKQVARLLEAQLQAQSLEHEEEVEHLKAQLEALKEE- 1371

Query: 1425 QNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTEL 1484
                                +DK+Q+ F + L        E Q E    Q+ SR L+ E 
Sbjct: 1372 --------------------MDKQQQTFCQTL----LLSPEAQVEFGVQQEISR-LTNEN 1406

Query: 1485 FKVKNVYEESLDQLETLRRENKNLQQEISDL--TEQIAEGGKQIHELEKIKKQVEQEKCE 1542
              +K + E+       L+++ K   ++  DL   + +A+  ++ HEL + +  V++++ +
Sbjct: 1407 LDLKELVEKLEKNERKLKKQLKIYMKKAQDLEAAQALAQSERKRHELNR-QVTVQRKEKD 1465

Query: 1543 IQAALEEAEASLEHEEGKILRIQLELNQVKSEV 1575
             Q  LE       H+E + L I+  +  +K ++
Sbjct: 1466 FQGMLE------YHKEDEALLIRNLVTDLKPQM 1492



 Score = 64.3 bits (155), Expect = 1e-09
 Identities = 120/572 (20%), Positives = 229/572 (40%), Gaps = 106/572 (18%)

Query: 1359 ELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLE 1418
            +LQR + + N E      +        T E+E  KK+L    Q   E             
Sbjct: 929  QLQRKIDEQNKEFKTLSEQLSVTTSTYTMEVERLKKELVHYQQSPGED------------ 976

Query: 1419 KTKQRLQNEVEDLMLDVERSNAACAAL--------------------------DKKQRNF 1452
             T  RLQ EVE L  +++R+++    L                          D+K++  
Sbjct: 977  -TSLRLQEEVESLRTELQRAHSERKILEDAHSREKDELRKRVADLEQENALLKDEKEQLN 1035

Query: 1453 DKVLSEWKQKYEET-------QAELEASQKESRSLSTELFKVKNVYEESLDQLETLR--- 1502
            +++L + K ++ +        + ELE  +   ++L  E  +++  Y+   D++  ++   
Sbjct: 1036 NQILCQSKDEFAQNSVKENLMKKELEEERSRYQNLVKEYSQLEQRYDNLRDEMTIIKQTP 1095

Query: 1503 --RENKNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQA-------ALEEAEAS 1553
              R N + Q  +   +   +    +I + E   +QVE+   E  A        L++    
Sbjct: 1096 GHRRNPSNQSSLESDSNYPSISTSEIGDTEDALQQVEEIGLEKAAMDMTVFLKLQKRVRE 1155

Query: 1554 LEHEEGKILRIQLELNQVKSEVDRKIAEKDEEID-QLKRNHTRVVETMQSTLDAEIRSRN 1612
            LE E  K   +Q++L + + +  +K+  +  + D  L  N      +++     E+ S N
Sbjct: 1156 LEQERKK---LQVQLEKREQQDSKKVQAEPPQTDIDLDPNADLAYNSLKR---QELESEN 1209

Query: 1613 DALRVKKKMEGDLNEMEIQLNHANRLAAESLRNYRNTQGILKETQLHLDDALRGQEDL-- 1670
                  KK++ DLNE+        +  A+      ++ G      L L+      E+L  
Sbjct: 1210 ------KKLKNDLNEL-------RKAVADQATQNNSSHGSPDSYSLLLNQLKLAHEELEV 1256

Query: 1671 -KEQLAIVERRANLLQAEIEELW---ATLEQTERSRKIAEQELLDASERVQLLH------ 1720
             KE++ I+  R  ++ A+   L    A      RS     ++ +D  + ++  H      
Sbjct: 1257 RKEEVLIL--RTQIVSADQRRLAGRNAEPNINARSSWPNSEKHVDQEDAIEAYHGVCQTN 1314

Query: 1721 --TQNTSLINTKKKL---ENDVSQLQSEVEEVIQ-ESRNAEEKAKKAITDAAMMAEELKK 1774
              T++   +N   +L      + Q+   +E  +Q +S   EE+ +        + EE+ K
Sbjct: 1315 SKTEDWGYLNEDGELGLAYQGLKQVARLLEAQLQAQSLEHEEEVEHLKAQLEALKEEMDK 1374

Query: 1775 EQDTSAH--LERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVENE 1832
            +Q T     L   +  +E  V+    RL   E L L   K+ ++KLE   R+L+ +++  
Sbjct: 1375 QQQTFCQTLLLSPEAQVEFGVQQEISRLTN-ENLDL---KELVEKLEKNERKLKKQLKIY 1430

Query: 1833 QKR--NAEAVKGLRKHERRVKELTYQTEEDRK 1862
             K+  + EA + L + ER+  EL  Q    RK
Sbjct: 1431 MKKAQDLEAAQALAQSERKRHELNRQVTVQRK 1462



 Score = 44.3 bits (103), Expect = 0.001
 Identities = 71/327 (21%), Positives = 123/327 (37%), Gaps = 69/327 (21%)

Query: 1676 IVERRANLLQAEIEELWATLEQTERSRKIA-----EQELLDASERVQLLHTQNTSLINTK 1730
            ++E +A  +Q  +   W      +R R  A        +L A   ++ L  +  S  + K
Sbjct: 859  LMEHKATTIQKHVRG-WMARRHFQRLRDAAIVIQCAFRMLKARRELKALRIEARSAEHLK 917

Query: 1731 KK---LENDVSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKE---------QDT 1778
            +    +EN V QLQ +++E  +E +   E+     +   M  E LKKE         +DT
Sbjct: 918  RLNVGMENKVVQLQRKIDEQNKEFKTLSEQLSVTTSTYTMEVERLKKELVHYQQSPGEDT 977

Query: 1779 SAHLE-------------------------RMKKNLEQTVKDLQHR----LDEAEQL--- 1806
            S  L+                         R K  L + V DL+       DE EQL   
Sbjct: 978  SLRLQEEVESLRTELQRAHSERKILEDAHSREKDELRKRVADLEQENALLKDEKEQLNNQ 1037

Query: 1807 ALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHERRVKEL------TYQTEED 1860
             L   K +  +   +   ++ E+E E+ R    VK   + E+R   L        QT   
Sbjct: 1038 ILCQSKDEFAQNSVKENLMKKELEEERSRYQNLVKEYSQLEQRYDNLRDEMTIIKQTPGH 1097

Query: 1861 RKNVLRLQDL----------VDKLQAKVKSYKRQAEEAEEQSNANLSKFRKLQHELEEAE 1910
            R+N      L            ++     + ++  E   E++  +++ F KLQ  + E E
Sbjct: 1098 RRNPSNQSSLESDSNYPSISTSEIGDTEDALQQVEEIGLEKAAMDMTVFLKLQKRVRELE 1157

Query: 1911 ERADIAESQVNKLRVKSREVHTKISAE 1937
            +     + Q+ K   + ++   K+ AE
Sbjct: 1158 QERKKLQVQLEK---REQQDSKKVQAE 1181


>gi|28416946 myosin 18A isoform a [Homo sapiens]
          Length = 2054

 Score =  503 bits (1296), Expect = e-142
 Identities = 437/1751 (24%), Positives = 823/1751 (47%), Gaps = 238/1751 (13%)

Query: 18   YLRKSEKERIEAQNKPFDAKTSVFVAEPKE------------------SYVKSTIQSKEG 59
            +LR  E  R E    P DAKT   +A  +                   S +KS   +   
Sbjct: 320  WLRSGEGPRRE----PSDAKTEEQIAAEEAWNETEKVWLVHRDGFSLASQLKSEELNLPE 375

Query: 60   GKVTVKTE-GGATLTVREDQVFPMNPPKYDKIEDMAMMTHLHEPGVLYNLKERYAAWMIY 118
            GKV VK +  GA L V ED V   N P  D++ED+A + +L+E  VL+ L++RY A +++
Sbjct: 376  GKVRVKLDHDGAILDVDEDDVEKANAPSCDRLEDLASLVYLNESSVLHTLRQRYGASLLH 435

Query: 119  TYSGLFCVTVNPYKWLPVYKPEVVAAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSIL 178
            TY+G   + + P     VY  +V+  ++G +R++  PHI++++  AY+ ML  R++QSI+
Sbjct: 436  TYAGPSLLVLGPRGAPAVYSEKVMHMFKGCRREDMAPHIYAVAQTAYRAMLMSRQDQSII 495

Query: 179  ITGESGAGKTVNTKRVIQYFATIAVTGEKKKDESGKMQGTLEDQIISANPLLEAFGNAKT 238
            + G SG+GKT + + ++QY ATIA     K     K Q        +   LLEAFGN+ T
Sbjct: 496  LLGSSGSGKTTSCQHLVQYLATIAGISGNKVFSVEKWQ--------ALYTLLEAFGNSPT 547

Query: 239  VRNDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQITS---- 294
            + N N++RF + + + F   G++ASA I+T LLEK RV  +  +E ++++FY + +    
Sbjct: 548  IINGNATRFSQILSLDFDQAGQVASASIQTMLLEKLRVARRPASEATFNVFYYLLACGDG 607

Query: 295  NKKPDLIEMLLITTNPYDYAFVSQGEITVPSIDDQEELMATDSAIDILGFTPEEKVSIYK 354
              + +L    L   N +    +++ E    +     +L A   A+ +LG +P+E+ + + 
Sbjct: 608  TLRTELHLNHLAENNVFGIVPLAKPEEKQKAAQQFSKLQA---AMKVLGISPDEQKACWF 664

Query: 355  LTGAVMHYGNMKFKQKQREEQAEPDGT-EVADKAAYLQSLNSADLLKALCYPRVKVG--- 410
            +  A+ H G     ++  E   +     E A KAAYL   +  +L  A+   + K G   
Sbjct: 665  ILAAIYHLGAAGATKEAAEAGRKQFARHEWAQKAAYLLGCSLEELSSAIFKHQHKGGTLQ 724

Query: 411  -NEYVTKGQTVQQVYNAVG----------ALAKAVYEKMFLWMVTRINQQLDTKQPRQYF 459
             +    +G     + +  G           +A  +Y ++F  +V+ +N+ L + Q     
Sbjct: 725  RSTSFRQGPEESGLGDGTGPKLSALECLEGMAAGLYSELFTLLVSLVNRALKSSQHSLCS 784

Query: 460  IGVLDIAGFEIFDFN------SLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTF 513
            + ++D  GF+  +        S E+LC N+T ++LQ+ F+   FV E E YK+E IE  F
Sbjct: 785  MMIVDTPGFQNPEQGGSARGASFEELCHNYTQDRLQRLFHERTFVQELERYKEENIELAF 844

Query: 514  IDF---------GMDLAACIELI------EKPLGIFSILEEECMFPKATDTSFKNKLYDQ 558
             D           +D A+   L+      ++  G+  +LEEE + P A++ +   +L+  
Sbjct: 845  DDLEPPTDDSVAAVDQASHQSLVRSLARTDEARGLLWLLEEEALVPGASEDTLLERLFSY 904

Query: 559  HLGKSAN--FQKPKVVKGKAEAHFSLIHYAGT--VDYNITGWLDKNK-DPLNDTVVGLYQ 613
            +  +  +   Q P +   K   HF L H  GT  V+YN+TGWL+  K +P       L Q
Sbjct: 905  YGPQEGDKKGQSPLLHSSKPH-HFLLGHSHGTNWVEYNVTGWLNYTKQNPATQNAPRLLQ 963

Query: 614  KSAMKTLASLF-----------STYASAEADSS-AKKGAKKKGSSFQTVSALFRE----- 656
             S  K +++LF            + A  E  S  A + A     +F T  A  ++     
Sbjct: 964  DSQKKIISNLFLGRAGSATVLSGSIAGLEGGSQLALRRATSMRKTFTTGMAAVKKKSLCI 1023

Query: 657  ----NLNKLMTNLRSTHPHFVRCIIP--------------------NETKTPGA------ 686
                 ++ L+  ++ +  HFV C +P                    +E   P        
Sbjct: 1024 QMKLQVDALIDTIKKSKLHFVHCFLPVAEGWAGEPRSASSRRVSSSSELDLPSGDHCEAG 1083

Query: 687  ---MEHELVLHQLRCNGVLEGIRICRKGFPSRILYGDFKQRYKVLNASAIPEGQ----FI 739
               ++  L+  QLR + +L+ +R+ R+G+P  +++ +F++R+ VL      +       +
Sbjct: 1084 LLQLDVPLLRTQLRGSRLLDAMRMYRQGYPDHMVFSEFRRRFDVLAPHLTKKHGRNYIVV 1143

Query: 740  DSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDEKLAQIITRTQAVCRGFL 799
            D ++A E+LL  +D++ +    G ++VFF+AG L  LEE RDE+ ++ +T  QA CRG+L
Sbjct: 1144 DERRAVEELLECLDLEKSSCCMGLSRVFFRAGTLARLEEQRDEQTSRNLTLFQAACRGYL 1203

Query: 800  MRVEYQKMLQRREALFCIQYNVRAFMNVKHWPWMKLFFKIKPLLKSAETEKEMATMKEEF 859
             R  ++K   +  A+ C+Q N++    VK WPW KLF  ++PL++   +E+++    EE 
Sbjct: 1204 ARQHFKKRKIQDLAIRCVQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKDEEI 1263

Query: 860  QKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLADAEERCEQLIKNKIQLE 919
            Q+ + +L K+E +R EL      L    ++L  ++  E ++   A +  +     +++ E
Sbjct: 1264 QQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDAETAERLRAE 1323

Query: 920  AKIKEVTER--AEEEEEINAELTAKKRKLEDECSELKKDIDDLEL---TLAKVEKEKHAT 974
             ++KE+  +  A +++    E+   + +L    +E+  ++DD +       K E+     
Sbjct: 1324 KEMKELQTQYDALKKQMEVMEMEVMEARL-IRAAEINGEVDDDDAGGEWRLKYERAVREV 1382

Query: 975  ENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDK----VNILTKAKTKL 1030
            +   K L +E    ++ +    + K+ L    ++ L DLQA+ ++    +  L K   +L
Sbjct: 1383 DFTKKRLQQE---FEDKLEVEQQNKRQL----ERRLGDLQADSEESQRALQQLKKKCQRL 1435

Query: 1031 EQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQLDEKLEKKEFEI 1090
              ++ D +  LE ++    +LE+ +R+ + +L  A E     +  +++L  + +    E 
Sbjct: 1436 TAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEA 1495

Query: 1091 SNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQRSDLSRELEEIS 1150
             +L  ++E++        +K+  L+A ++++  +   + AS AK +KQ  DL  ++++  
Sbjct: 1496 FSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQE 1555

Query: 1151 ERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRKKHADSMAELGEQI 1210
            E L+E  G                      LE+A L+ E  +  +R+ H+  M    E++
Sbjct: 1556 EELDEQAGTIQM------------------LEQAKLRLEMEMERMRQTHSKEMESRDEEV 1597

Query: 1211 DNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGNLEKMCRSLEDQVSELKTKEEEQQ 1270
               +  +Q  +K+  +++++ ++   + + + + K  LE    +L DQV+  +   E ++
Sbjct: 1598 ---EEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVN--RRDFESEK 1652

Query: 1271 RLINDLTAQRARL----------------QTEAGEYSRQLDEKDALVSQLSRSKQASTQQ 1314
            RL  DL   +A L                + E  +   QL+E +   +   ++++A   +
Sbjct: 1653 RLRKDLKRTKALLADAQLMLDHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVE 1712

Query: 1315 IEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQW 1374
            IE+L  Q+++  KAK AL   L   + + + ++ + EE+QE   EL   + K  + VAQ 
Sbjct: 1713 IEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNEL---MKKHKAAVAQ- 1768

Query: 1375 RTKYETDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLD 1434
                             A + LAQ + + +  +E  N +   L++  Q LQ++VE L   
Sbjct: 1769 -----------------ASRDLAQ-INDLQAQLEEANKEKQELQEKLQALQSQVEFL--- 1807

Query: 1435 VERSNAACAALDKKQRNFDKVL---SEWKQKYEETQAELEASQ-KESRSLSTELFKVKNV 1490
                         +Q   DK L    E K +  ET+ E E +Q K   SL++ L +    
Sbjct: 1808 -------------EQSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEK 1854

Query: 1491 YEESLDQL----ETLRRENKNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAA 1546
              E  DQ        + +NK LQ+++ D  E++ E  ++  E  + K ++E +   ++AA
Sbjct: 1855 LTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAA 1914

Query: 1547 LEEAEASLEHEEGKILRIQLEL-NQVKSEVDRKIAEKDEEIDQLKRNHTRVVETMQSTLD 1605
             +  +A L+    +I  +Q  + ++++S+ +  +    +++    +     +E   S +D
Sbjct: 1915 NQSLQADLKLAFKRIGDLQAAIEDEMESDENEDLINSLQDMVTKYQKRKNKLEG-DSDVD 1973

Query: 1606 AEIRSRNDALR 1616
            +E+  R D ++
Sbjct: 1974 SELEDRVDGVK 1984



 Score =  189 bits (479), Expect = 3e-47
 Identities = 170/709 (23%), Positives = 334/709 (47%), Gaps = 91/709 (12%)

Query: 1249 EKMCRSLEDQVSELKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQLSRSK 1308
            E+  R+ ++++ +L++K E+ ++  N+L     RL++   E + +L ++        R+ 
Sbjct: 1253 EEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDE--------RNT 1304

Query: 1309 QASTQQIEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYE--EEQEGKAELQRALSK 1366
              S  Q+      L+ ET  +      ++  +   D L++Q E  E +  +A L RA ++
Sbjct: 1305 GESASQL------LDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRA-AE 1357

Query: 1367 ANSEV------AQWRTKYETDAIQ--------------RTEELEEAKKKLAQRLQEAEEH 1406
             N EV       +WR KYE    +              + E  ++ K++L +RL + +  
Sbjct: 1358 INGEVDDDDAGGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQAD 1417

Query: 1407 VEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEET 1466
             E        L+K  QRL  E++D  L +E        L+KKQR FD  LS+  ++ +  
Sbjct: 1418 SEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQRE 1477

Query: 1467 QAELEASQKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEISDLTEQIAEGGKQI 1526
            + + E  Q+E   L  E F +K   EE    +    ++  +L+ E+ D++ Q +   K  
Sbjct: 1478 KLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQES---KDE 1534

Query: 1527 HELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKI-------LRIQLELNQVKSEVDRKI 1579
              L K+KKQ+     +++A +++ E  L+ + G I       LR+++E+ +++    +++
Sbjct: 1535 ASLAKVKKQLR----DLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEM 1590

Query: 1580 AEKDEEIDQLKRNHTRVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEMEIQLNHANRLA 1639
              +DEE+++ +++  + ++ M+  L+ E   +   LR K+++EG L  +  Q+N  +  +
Sbjct: 1591 ESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVNRRDFES 1650

Query: 1640 AESLR-NYRNTQGILKETQLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELWATLEQT 1698
             + LR + + T+ +L + QL LD  L+     K ++A        L+ ++EE   T    
Sbjct: 1651 EKRLRKDLKRTKALLADAQLMLDH-LKNSAPSKREIA-------QLKNQLEESEFTCAAA 1702

Query: 1699 ERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQESRNAEEKA 1758
             ++RK  E E+ D       LH Q   +   K  LE  +S+LQ E  E+       +E  
Sbjct: 1703 VKARKAMEVEIED-------LHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQED- 1754

Query: 1759 KKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKL 1818
                     M E +KK +   A   R   +L Q + DLQ +L+EA         K+ Q+L
Sbjct: 1755 ---------MNELMKKHKAAVAQASR---DLAQ-INDLQAQLEEAN--------KEKQEL 1793

Query: 1819 EARVRELEGEVENEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQAKV 1878
            + +++ L+ +VE  ++   +    + + E +++EL  + E +R  V RL+ L  +L+  +
Sbjct: 1794 QEKLQALQSQVEFLEQSMVDKSL-VSRQEAKIRELETRLEFERTQVKRLESLASRLKENM 1852

Query: 1879 KSYKRQAEEAEEQSNANLSKFRKLQHELEEA-EERADIAESQVNKLRVK 1926
            +    + ++     N    + ++LQ +L +  EE  ++A  +    R K
Sbjct: 1853 EKLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAEASRKK 1901



 Score =  148 bits (373), Expect = 6e-35
 Identities = 197/909 (21%), Positives = 404/909 (44%), Gaps = 114/909 (12%)

Query: 942  KKRKLED--ECSELKKDIDDLEL--------TLAKVEKEKHATENKVKNLTEEMAGLDET 991
            ++R +E+  EC +L+K    + L        TLA++E+++   E   +NLT   A     
Sbjct: 1145 ERRAVEELLECLDLEKSSCCMGLSRVFFRAGTLARLEEQRD--EQTSRNLTLFQAACRGY 1202

Query: 992  IAKLSKEKKALQETH----QQTLDDLQAEEDKV--NILTKAKTKLEQQVDD--LEGSLEQ 1043
            +A+   +K+ +Q+      Q+ +   +  +D     + T  +  +E Q+ +  +    E+
Sbjct: 1203 LARQHFKKRKIQDLAIRCVQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKDEE 1262

Query: 1044 EKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQLDEKLEKKEFEISNLISKIEDEQAV 1103
             ++LR  LE+A+++   +L+L  +    +E+   +L  +L  +     +    ++ E A 
Sbjct: 1263 IQQLRSKLEKAEKE-RNELRLNSDR---LESRISELTSELTDERNTGESASQLLDAETAE 1318

Query: 1104 EIQLQKKIKELQARIEELGEEIEAERASRAKAEKQRS-DLSRELEEISERLEEAGGATSA 1162
             ++ +K++KELQ + + L +++E       +A   R+ +++ E+++     ++AGG    
Sbjct: 1319 RLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDD-----DDAGGEWRL 1373

Query: 1163 QVELNKKREAEFQK--LRRDLEEATLQHEAMVAALRKKHADSMAELGEQIDNLQRVKQKL 1220
            + E    RE +F K  L+++ E+     +     L ++  D  A+  E     QR  Q+L
Sbjct: 1374 KYE-RAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEES----QRALQQL 1428

Query: 1221 EKEKSELKMETDDLSSNAEAISKAKGNLEKMCRSLEDQVSELKTKEEEQQRLINDLTAQR 1280
            +K+   L  E  D   + E        LEK  R  + ++S+   + + ++     L  ++
Sbjct: 1429 KKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREK 1488

Query: 1281 ARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKHQLEEETKAKNALAHALQSSR 1340
              L  EA    +QL+EKD  ++  ++   +   +++++  Q   E+K + +LA   +  R
Sbjct: 1489 DMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQ---ESKDEASLAKVKKQLR 1545

Query: 1341 HDCDLLREQYEE--EQEGKAE-LQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLA 1397
                 +++Q EE  EQ G  + L++A  +   E+ + R  +  +   R EE+EEA++   
Sbjct: 1546 DLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQ 1605

Query: 1398 QRLQEAEEHVEA--------------VNAKCASLEKTKQRLQNEVED-LMLDVERSNAAC 1442
            ++L++ E  +E               +  K A+L     R   E E  L  D++R+ A  
Sbjct: 1606 KKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALL 1665

Query: 1443 A----ALD--KKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTEL----------FK 1486
            A     LD  K      + +++ K + EE++    A+ K  +++  E+           K
Sbjct: 1666 ADAQLMLDHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAK 1725

Query: 1487 VKNVYEESLDQLETLRRENKN-LQQEISDLTE-------QIAEGGKQIHELEKIKKQVEQ 1538
             K   EE L +L+  + E +N L+++  D+ E        +A+  + + ++  ++ Q+E+
Sbjct: 1726 AKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEE 1785

Query: 1539 ---EKCEIQAALEEAEASLEHEEGKILRIQLELNQVKS--EVDRKIAEKDEEIDQLKRNH 1593
               EK E+Q  L+  ++ +E  E  ++   L   Q     E++ ++  +  ++ +L+   
Sbjct: 1786 ANKEKQELQEKLQALQSQVEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLA 1845

Query: 1594 TRVVETMQSTL---DAEIRSRNDALRVKKKMEGDLNEMEIQLNHANRLAAESLRNYRNTQ 1650
            +R+ E M+      D  I + N      K+++  L + + ++    R  AE+ R      
Sbjct: 1846 SRLKENMEKLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAEASRKKH--- 1902

Query: 1651 GILKETQLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELWATLEQTERSRKIAEQELL 1710
                E ++ L+      + L+  L +  +R   LQA IE+               E E  
Sbjct: 1903 ----ELEMDLESLEAANQSLQADLKLAFKRIGDLQAAIED---------------EMESD 1943

Query: 1711 DASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAE 1770
            +  + +  L    T     K KLE D S + SE+E+ +   ++   K  K  + AA    
Sbjct: 1944 ENEDLINSLQDMVTKYQKRKNKLEGD-SDVDSELEDRVDGVKSWLSK-NKGPSKAASDDG 2001

Query: 1771 ELKKEQDTS 1779
             LK    TS
Sbjct: 2002 SLKSSSPTS 2010



 Score = 99.0 bits (245), Expect = 4e-20
 Identities = 124/596 (20%), Positives = 263/596 (44%), Gaps = 74/596 (12%)

Query: 1346 LREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKK--KLAQRLQEA 1403
            +R + EE Q+ +++L++A  K  +E+     + E+   + T EL + +   + A +L +A
Sbjct: 1256 IRNKDEEIQQLRSKLEKA-EKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDA 1314

Query: 1404 E--EHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQ 1461
            E  E + A   +   L+     L+ ++E + ++V  +    AA    + + D    EW+ 
Sbjct: 1315 ETAERLRA-EKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWRL 1373

Query: 1462 KYEETQAELEASQKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEISDLTEQIAE 1521
            KYE    E++             F  K + +E  D+LE  ++  + L++ + DL     E
Sbjct: 1374 KYERAVREVD-------------FTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEE 1420

Query: 1522 GGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAE 1581
              + + +L+K  +++  E  + +  LE  +      E K  R   EL+Q   E  R+  +
Sbjct: 1421 SQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQ 1480

Query: 1582 KDEEIDQLKRNHTRVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEMEIQLNHANRLAAE 1641
            + E++ + K        +++  L+ +        +    +E +L ++  Q +      A+
Sbjct: 1481 R-EKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAK 1539

Query: 1642 SLRNYRNTQGILKETQLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELWATLEQTERS 1701
              +  R+ +  +K+ +  LD+           + ++E+    L+ E+E +  T  +   S
Sbjct: 1540 VKKQLRDLEAKVKDQEEELDEQAG-------TIQMLEQAKLRLEMEMERMRQTHSKEMES 1592

Query: 1702 RKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEE---VIQESRNAEEKA 1758
            R   ++E+ +A +  Q             KKL+    QL+ E E+   V++E R  E K 
Sbjct: 1593 R---DEEVEEARQSCQ-------------KKLKQMEVQLEEEYEDKQKVLREKRELEGKL 1636

Query: 1759 KKAITDAAMMAEELKKEQDTSAHLERMKKNLEQT---VKDLQHRLDEAEQLALKGGKKQI 1815
                   A +++++ +    S   +R++K+L++T   + D Q  LD  +  A        
Sbjct: 1637 -------ATLSDQVNRRDFESE--KRLRKDLKRTKALLADAQLMLDHLKNSAPS------ 1681

Query: 1816 QKLEARVRELEGEVENEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQ 1875
               +  + +L+ ++E  +   A AVK  +  E  +++L  Q ++  K    L++ + +LQ
Sbjct: 1682 ---KREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQ 1738

Query: 1876 AKVKSYKRQAEEAEEQSNANLSKFRKLQHELEEAEERADIAESQVNKLRVKSREVH 1931
             +    + + EE +E  N  + K     H+   A+   D+A  Q+N L+ +  E +
Sbjct: 1739 REKNEIQNRLEEDQEDMNELMKK-----HKAAVAQASRDLA--QINDLQAQLEEAN 1787



 Score = 88.2 bits (217), Expect = 7e-17
 Identities = 133/648 (20%), Positives = 277/648 (42%), Gaps = 107/648 (16%)

Query: 1364 LSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQR 1423
            L K++  +   R  +    + R EE         QR ++   ++    A C      +  
Sbjct: 1158 LEKSSCCMGLSRVFFRAGTLARLEE---------QRDEQTSRNLTLFQAACRGYLARQHF 1208

Query: 1424 LQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQ-KYEETQAELEASQKESRSLST 1482
             + +++DL +        C   + K+    K    WK         E++ S+++ R+   
Sbjct: 1209 KKRKIQDLAI-------RCVQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKDE 1261

Query: 1483 ELFKVKNVYEESLDQLETLRRENKNLQQEISDLTEQIA------EGGKQIHELEKIKK-Q 1535
            E+ ++++  E++  +   LR  +  L+  IS+LT ++       E   Q+ + E  ++ +
Sbjct: 1262 EIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDAETAERLR 1321

Query: 1536 VEQEKCEIQAALEEAEASLEHEEGKILRIQL-ELNQVKSEVDRKIAEKDEEIDQLKRNHT 1594
             E+E  E+Q   +  +  +E  E +++  +L    ++  EVD      D+   + +  + 
Sbjct: 1322 AEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVD-----DDDAGGEWRLKYE 1376

Query: 1595 RVVETMQSTLDAEIRSRNDALRV----KKKMEGDLNEMEIQLNHANRLAAESLRNYRNTQ 1650
            R V  +  T     +   D L V    K+++E  L +++     + R   +  +  +   
Sbjct: 1377 RAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLT 1436

Query: 1651 GILKETQLHLDDALRGQEDLKEQLAIVERR--ANLLQAEIEELWATLEQTERSRKIAEQE 1708
              L++T+LHL+    GQ+    +L   +RR  + L QA  E   A  E+ +R +   E++
Sbjct: 1437 AELQDTKLHLE----GQQVRNHELEKKQRRFDSELSQAHEE---AQREKLQREKLQREKD 1489

Query: 1709 LL--DASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVI-QESRNAEE--KAKKAIT 1763
            +L  +A    Q L  ++  +    +K    V  L++E++++  QES++     K KK + 
Sbjct: 1490 MLLAEAFSLKQQLEEKDMDIAGFTQK----VVSLEAELQDISSQESKDEASLAKVKKQLR 1545

Query: 1764 DAAMMA----EELKKEQDTSAHLERMKKNLEQTV--------KDLQHRLDEAEQLALKGG 1811
            D         EEL ++  T   LE+ K  LE  +        K+++ R +E E+ A +  
Sbjct: 1546 DLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEE-ARQSC 1604

Query: 1812 KKQIQKLEARV--------------RELEGEV----ENEQKRNAEAVKGLRKHERRVKEL 1853
            +K+++++E ++              RELEG++    +   +R+ E+ K LRK  +R K L
Sbjct: 1605 QKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKAL 1664

Query: 1854 TYQTE----------EDRKNVLRLQDLVDKLQ----AKVKSYKRQAEEAEE--------- 1890
                +            ++ + +L++ +++ +    A VK+ K    E E+         
Sbjct: 1665 LADAQLMLDHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIA 1724

Query: 1891 -QSNANLSKFRKLQHELEEAEERADIAESQVNKLRVKSREVHTKISAE 1937
                A   +  +LQ E  E + R +  +  +N+L  K +    + S +
Sbjct: 1725 KAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRD 1772


>gi|42794779 myosin 18A isoform b [Homo sapiens]
          Length = 2039

 Score =  502 bits (1293), Expect = e-141
 Identities = 434/1724 (25%), Positives = 813/1724 (47%), Gaps = 239/1724 (13%)

Query: 18   YLRKSEKERIEAQNKPFDAKTSVFVAEPKE------------------SYVKSTIQSKEG 59
            +LR  E  R E    P DAKT   +A  +                   S +KS   +   
Sbjct: 320  WLRSGEGPRRE----PSDAKTEEQIAAEEAWNETEKVWLVHRDGFSLASQLKSEELNLPE 375

Query: 60   GKVTVKTE-GGATLTVREDQVFPMNPPKYDKIEDMAMMTHLHEPGVLYNLKERYAAWMIY 118
            GKV VK +  GA L V ED V   N P  D++ED+A + +L+E  VL+ L++RY A +++
Sbjct: 376  GKVRVKLDHDGAILDVDEDDVEKANAPSCDRLEDLASLVYLNESSVLHTLRQRYGASLLH 435

Query: 119  TYSGLFCVTVNPYKWLPVYKPEVVAAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSIL 178
            TY+G   + + P     VY  +V+  ++G +R++  PHI++++  AY+ ML  R++QSI+
Sbjct: 436  TYAGPSLLVLGPRGAPAVYSEKVMHMFKGCRREDMAPHIYAVAQTAYRAMLMSRQDQSII 495

Query: 179  ITGESGAGKTVNTKRVIQYFATIAVTGEKKKDESGKMQGTLEDQIISANPLLEAFGNAKT 238
            + G SG+GKT + + ++QY ATIA     K     K Q        +   LLEAFGN+ T
Sbjct: 496  LLGSSGSGKTTSCQHLVQYLATIAGISGNKVFSVEKWQ--------ALYTLLEAFGNSPT 547

Query: 239  VRNDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQITS---- 294
            + N N++RF + + + F   G++ASA I+T LLEK RV  +  +E ++++FY + +    
Sbjct: 548  IINGNATRFSQILSLDFDQAGQVASASIQTMLLEKLRVARRPASEATFNVFYYLLACGDG 607

Query: 295  NKKPDLIEMLLITTNPYDYAFVSQGEITVPSIDDQEELMATDSAIDILGFTPEEKVSIYK 354
              + +L    L   N +    +++ E    +     +L A   A+ +LG +P+E+ + + 
Sbjct: 608  TLRTELHLNHLAENNVFGIVPLAKPEEKQKAAQQFSKLQA---AMKVLGISPDEQKACWF 664

Query: 355  LTGAVMHYGNMKFKQKQREEQAEPDGT-EVADKAAYLQSLNSADLLKALCYPRVKVG--- 410
            +  A+ H G     ++  E   +     E A KAAYL   +  +L  A+   + K G   
Sbjct: 665  ILAAIYHLGAAGATKEAAEAGRKQFARHEWAQKAAYLLGCSLEELSSAIFKHQHKGGTLQ 724

Query: 411  -NEYVTKGQTVQQVYNAVG----------ALAKAVYEKMFLWMVTRINQQLDTKQPRQYF 459
             +    +G     + +  G           +A  +Y ++F  +V+ +N+ L + Q     
Sbjct: 725  RSTSFRQGPEESGLGDGTGPKLSALECLEGMAAGLYSELFTLLVSLVNRALKSSQHSLCS 784

Query: 460  IGVLDIAGFEIFDFN------SLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTF 513
            + ++D  GF+  +        S E+LC N+T ++LQ+ F+   FV E E YK+E IE  F
Sbjct: 785  MMIVDTPGFQNPEQGGSARGASFEELCHNYTQDRLQRLFHERTFVQELERYKEENIELAF 844

Query: 514  IDF---------GMDLAACIELI------EKPLGIFSILEEECMFPKATDTSFKNKLYDQ 558
             D           +D A+   L+      ++  G+  +LEEE + P A++ +   +L+  
Sbjct: 845  DDLEPPTDDSVAAVDQASHQSLVRSLARTDEARGLLWLLEEEALVPGASEDTLLERLFSY 904

Query: 559  HLGKSAN--FQKPKVVKGKAEAHFSLIHYAGT--VDYNITGWLDKNK-DPLNDTVVGLYQ 613
            +  +  +   Q P +   K   HF L H  GT  V+YN+TGWL+  K +P       L Q
Sbjct: 905  YGPQEGDKKGQSPLLHSSKPH-HFLLGHSHGTNWVEYNVTGWLNYTKQNPATQNAPRLLQ 963

Query: 614  KSAMKTLASLF-----------STYASAEADSS-AKKGAKKKGSSFQTVSALFRE----- 656
             S  K +++LF            + A  E  S  A + A     +F T  A  ++     
Sbjct: 964  DSQKKIISNLFLGRAGSATVLSGSIAGLEGGSQLALRRATSMRKTFTTGMAAVKKKSLCI 1023

Query: 657  ----NLNKLMTNLRSTHPHFVRCIIP--------------------NETKTPGA------ 686
                 ++ L+  ++ +  HFV C +P                    +E   P        
Sbjct: 1024 QMKLQVDALIDTIKKSKLHFVHCFLPVAEGWAGEPRSASSRRVSSSSELDLPSGDHCEAG 1083

Query: 687  ---MEHELVLHQLRCNGVLEGIRICRKGFPSRILYGDFKQRYKVLNASAIPEGQ----FI 739
               ++  L+  QLR + +L+ +R+ R+G+P  +++ +F++R+ VL      +       +
Sbjct: 1084 LLQLDVPLLRTQLRGSRLLDAMRMYRQGYPDHMVFSEFRRRFDVLAPHLTKKHGRNYIVV 1143

Query: 740  DSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDEKLAQIITRTQAVCRGFL 799
            D ++A E+LL  +D++ +    G ++VFF+AG L  LEE RDE+ ++ +T  QA CRG+L
Sbjct: 1144 DERRAVEELLECLDLEKSSCCMGLSRVFFRAGTLARLEEQRDEQTSRNLTLFQAACRGYL 1203

Query: 800  MRVEYQKMLQRREALFCIQYNVRAFMNVKHWPWMKLFFKIKPLLKSAETEKEMATMKEEF 859
             R  ++K   +  A+ C+Q N++    VK WPW KLF  ++PL++   +E+++    EE 
Sbjct: 1204 ARQHFKKRKIQDLAIRCVQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKDEEI 1263

Query: 860  QKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLADAEERCEQLIKNKIQLE 919
            Q+ + +L K+E +R EL      L    ++L  ++  E ++   A +  +     +++ E
Sbjct: 1264 QQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDAETAERLRAE 1323

Query: 920  AKIKEVTER--AEEEEEINAELTAKKRKLEDECSELKKDIDDLEL---TLAKVEKEKHAT 974
             ++KE+  +  A +++    E+   + +L    +E+  ++DD +       K E+     
Sbjct: 1324 KEMKELQTQYDALKKQMEVMEMEVMEARL-IRAAEINGEVDDDDAGGEWRLKYERAVREV 1382

Query: 975  ENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDK----VNILTKAKTKL 1030
            +   K L +E    ++ +    + K+ L    ++ L DLQA+ ++    +  L K   +L
Sbjct: 1383 DFTKKRLQQE---FEDKLEVEQQNKRQL----ERRLGDLQADSEESQRALQQLKKKCQRL 1435

Query: 1031 EQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQLDEKLEKKEFEI 1090
              ++ D +  LE ++    +LE+ +R+ + +L  A E     +  +++L  + +    E 
Sbjct: 1436 TAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEA 1495

Query: 1091 SNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQRSDLSRELEEIS 1150
             +L  ++E++        +K+  L+A ++++  +   + AS AK +KQ  DL  ++++  
Sbjct: 1496 FSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQE 1555

Query: 1151 ERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRKKHADSMAELGEQI 1210
            E L+E  G                      LE+A L+ E  +  +R+ H+  M    E++
Sbjct: 1556 EELDEQAGTIQM------------------LEQAKLRLEMEMERMRQTHSKEMESRDEEV 1597

Query: 1211 DNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGNLEKMCRSLEDQVSELKTKEEEQQ 1270
               +  +Q  +K+  +++++ ++   + + + + K  LE    +L DQV+  +   E ++
Sbjct: 1598 ---EEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVN--RRDFESEK 1652

Query: 1271 RLINDLTAQRARL----------------QTEAGEYSRQLDEKDALVSQLSRSKQASTQQ 1314
            RL  DL   +A L                + E  +   QL+E +   +   ++++A   +
Sbjct: 1653 RLRKDLKRTKALLADAQLMLDHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVE 1712

Query: 1315 IEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQW 1374
            IE+L  Q+++  KAK AL   L   + + + ++ + EE+QE   EL   + K  + VAQ 
Sbjct: 1713 IEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNEL---MKKHKAAVAQ- 1768

Query: 1375 RTKYETDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLD 1434
                             A + LAQ + + +  +E  N +   L++  Q LQ++VE L   
Sbjct: 1769 -----------------ASRDLAQ-INDLQAQLEEANKEKQELQEKLQALQSQVEFL--- 1807

Query: 1435 VERSNAACAALDKKQRNFDKVL---SEWKQKYEETQAELEASQ-KESRSLSTELFKVKNV 1490
                         +Q   DK L    E K +  ET+ E E +Q K   SL++ L +    
Sbjct: 1808 -------------EQSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEK 1854

Query: 1491 YEESLDQL----ETLRRENKNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAA 1546
              E  DQ        + +NK LQ+++ D  E++ E  ++  E  + K ++E +   ++AA
Sbjct: 1855 LTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAA 1914

Query: 1547 LEEAEASLEHEEGKILRIQLEL-NQVKSEVDRKI--AEKDEEID 1587
             +  +A L+    +I  +Q  + ++++S+ +  +  +E D ++D
Sbjct: 1915 NQSLQADLKLAFKRIGDLQAAIEDEMESDENEDLINSEGDSDVD 1958



 Score =  189 bits (479), Expect = 3e-47
 Identities = 170/709 (23%), Positives = 334/709 (47%), Gaps = 91/709 (12%)

Query: 1249 EKMCRSLEDQVSELKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQLSRSK 1308
            E+  R+ ++++ +L++K E+ ++  N+L     RL++   E + +L ++        R+ 
Sbjct: 1253 EEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDE--------RNT 1304

Query: 1309 QASTQQIEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYE--EEQEGKAELQRALSK 1366
              S  Q+      L+ ET  +      ++  +   D L++Q E  E +  +A L RA ++
Sbjct: 1305 GESASQL------LDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRA-AE 1357

Query: 1367 ANSEV------AQWRTKYETDAIQ--------------RTEELEEAKKKLAQRLQEAEEH 1406
             N EV       +WR KYE    +              + E  ++ K++L +RL + +  
Sbjct: 1358 INGEVDDDDAGGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQAD 1417

Query: 1407 VEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEET 1466
             E        L+K  QRL  E++D  L +E        L+KKQR FD  LS+  ++ +  
Sbjct: 1418 SEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQRE 1477

Query: 1467 QAELEASQKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEISDLTEQIAEGGKQI 1526
            + + E  Q+E   L  E F +K   EE    +    ++  +L+ E+ D++ Q +   K  
Sbjct: 1478 KLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQES---KDE 1534

Query: 1527 HELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKI-------LRIQLELNQVKSEVDRKI 1579
              L K+KKQ+     +++A +++ E  L+ + G I       LR+++E+ +++    +++
Sbjct: 1535 ASLAKVKKQLR----DLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEM 1590

Query: 1580 AEKDEEIDQLKRNHTRVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEMEIQLNHANRLA 1639
              +DEE+++ +++  + ++ M+  L+ E   +   LR K+++EG L  +  Q+N  +  +
Sbjct: 1591 ESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVNRRDFES 1650

Query: 1640 AESLR-NYRNTQGILKETQLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELWATLEQT 1698
             + LR + + T+ +L + QL LD  L+     K ++A        L+ ++EE   T    
Sbjct: 1651 EKRLRKDLKRTKALLADAQLMLDH-LKNSAPSKREIA-------QLKNQLEESEFTCAAA 1702

Query: 1699 ERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQESRNAEEKA 1758
             ++RK  E E+ D       LH Q   +   K  LE  +S+LQ E  E+       +E  
Sbjct: 1703 VKARKAMEVEIED-------LHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQED- 1754

Query: 1759 KKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKL 1818
                     M E +KK +   A   R   +L Q + DLQ +L+EA         K+ Q+L
Sbjct: 1755 ---------MNELMKKHKAAVAQASR---DLAQ-INDLQAQLEEAN--------KEKQEL 1793

Query: 1819 EARVRELEGEVENEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQAKV 1878
            + +++ L+ +VE  ++   +    + + E +++EL  + E +R  V RL+ L  +L+  +
Sbjct: 1794 QEKLQALQSQVEFLEQSMVDKSL-VSRQEAKIRELETRLEFERTQVKRLESLASRLKENM 1852

Query: 1879 KSYKRQAEEAEEQSNANLSKFRKLQHELEEA-EERADIAESQVNKLRVK 1926
            +    + ++     N    + ++LQ +L +  EE  ++A  +    R K
Sbjct: 1853 EKLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAEASRKK 1901



 Score =  140 bits (354), Expect = 9e-33
 Identities = 176/820 (21%), Positives = 373/820 (45%), Gaps = 97/820 (11%)

Query: 942  KKRKLED--ECSELKKDIDDLEL--------TLAKVEKEKHATENKVKNLTEEMAGLDET 991
            ++R +E+  EC +L+K    + L        TLA++E+++   E   +NLT   A     
Sbjct: 1145 ERRAVEELLECLDLEKSSCCMGLSRVFFRAGTLARLEEQRD--EQTSRNLTLFQAACRGY 1202

Query: 992  IAKLSKEKKALQETH----QQTLDDLQAEEDKV--NILTKAKTKLEQQVDD--LEGSLEQ 1043
            +A+   +K+ +Q+      Q+ +   +  +D     + T  +  +E Q+ +  +    E+
Sbjct: 1203 LARQHFKKRKIQDLAIRCVQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKDEE 1262

Query: 1044 EKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQLDEKLEKKEFEISNLISKIEDEQAV 1103
             ++LR  LE+A+++   +L+L  +    +E+   +L  +L  +     +    ++ E A 
Sbjct: 1263 IQQLRSKLEKAEKE-RNELRLNSDR---LESRISELTSELTDERNTGESASQLLDAETAE 1318

Query: 1104 EIQLQKKIKELQARIEELGEEIEAERASRAKAEKQRS-DLSRELEEISERLEEAGGATSA 1162
             ++ +K++KELQ + + L +++E       +A   R+ +++ E+++     ++AGG    
Sbjct: 1319 RLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDD-----DDAGGEWRL 1373

Query: 1163 QVELNKKREAEFQK--LRRDLEEATLQHEAMVAALRKKHADSMAELGEQIDNLQRVKQKL 1220
            + E    RE +F K  L+++ E+     +     L ++  D  A+  E     QR  Q+L
Sbjct: 1374 KYE-RAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEES----QRALQQL 1428

Query: 1221 EKEKSELKMETDDLSSNAEAISKAKGNLEKMCRSLEDQVSELKTKEEEQQRLINDLTAQR 1280
            +K+   L  E  D   + E        LEK  R  + ++S+   + + ++     L  ++
Sbjct: 1429 KKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREK 1488

Query: 1281 ARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKHQLEEETKAKNALAHALQSSR 1340
              L  EA    +QL+EKD  ++  ++   +   +++++  Q   E+K + +LA   +  R
Sbjct: 1489 DMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQ---ESKDEASLAKVKKQLR 1545

Query: 1341 HDCDLLREQYEE--EQEGKAE-LQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLA 1397
                 +++Q EE  EQ G  + L++A  +   E+ + R  +  +   R EE+EEA++   
Sbjct: 1546 DLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQ 1605

Query: 1398 QRLQEAEEHVEA--------------VNAKCASLEKTKQRLQNEVED-LMLDVERSNAAC 1442
            ++L++ E  +E               +  K A+L     R   E E  L  D++R+ A  
Sbjct: 1606 KKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALL 1665

Query: 1443 A----ALD--KKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTEL----------FK 1486
            A     LD  K      + +++ K + EE++    A+ K  +++  E+           K
Sbjct: 1666 ADAQLMLDHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAK 1725

Query: 1487 VKNVYEESLDQLETLRRENKN-LQQEISDLTE-------QIAEGGKQIHELEKIKKQVEQ 1538
             K   EE L +L+  + E +N L+++  D+ E        +A+  + + ++  ++ Q+E+
Sbjct: 1726 AKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEE 1785

Query: 1539 ---EKCEIQAALEEAEASLEHEEGKILRIQLELNQVKS--EVDRKIAEKDEEIDQLKRNH 1593
               EK E+Q  L+  ++ +E  E  ++   L   Q     E++ ++  +  ++ +L+   
Sbjct: 1786 ANKEKQELQEKLQALQSQVEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLA 1845

Query: 1594 TRVVETMQSTL---DAEIRSRNDALRVKKKMEGDLNEMEIQLNHANRLAAESLRNYRNTQ 1650
            +R+ E M+      D  I + N      K+++  L + + ++    R  AE+ R      
Sbjct: 1846 SRLKENMEKLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAEASRKKH--- 1902

Query: 1651 GILKETQLHLDDALRGQEDLKEQLAIVERRANLLQAEIEE 1690
                E ++ L+      + L+  L +  +R   LQA IE+
Sbjct: 1903 ----ELEMDLESLEAANQSLQADLKLAFKRIGDLQAAIED 1938



 Score = 99.0 bits (245), Expect = 4e-20
 Identities = 124/596 (20%), Positives = 263/596 (44%), Gaps = 74/596 (12%)

Query: 1346 LREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKK--KLAQRLQEA 1403
            +R + EE Q+ +++L++A  K  +E+     + E+   + T EL + +   + A +L +A
Sbjct: 1256 IRNKDEEIQQLRSKLEKA-EKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDA 1314

Query: 1404 E--EHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQ 1461
            E  E + A   +   L+     L+ ++E + ++V  +    AA    + + D    EW+ 
Sbjct: 1315 ETAERLRA-EKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWRL 1373

Query: 1462 KYEETQAELEASQKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEISDLTEQIAE 1521
            KYE    E++             F  K + +E  D+LE  ++  + L++ + DL     E
Sbjct: 1374 KYERAVREVD-------------FTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEE 1420

Query: 1522 GGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAE 1581
              + + +L+K  +++  E  + +  LE  +      E K  R   EL+Q   E  R+  +
Sbjct: 1421 SQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQ 1480

Query: 1582 KDEEIDQLKRNHTRVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEMEIQLNHANRLAAE 1641
            + E++ + K        +++  L+ +        +    +E +L ++  Q +      A+
Sbjct: 1481 R-EKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAK 1539

Query: 1642 SLRNYRNTQGILKETQLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELWATLEQTERS 1701
              +  R+ +  +K+ +  LD+           + ++E+    L+ E+E +  T  +   S
Sbjct: 1540 VKKQLRDLEAKVKDQEEELDEQAG-------TIQMLEQAKLRLEMEMERMRQTHSKEMES 1592

Query: 1702 RKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEE---VIQESRNAEEKA 1758
            R   ++E+ +A +  Q             KKL+    QL+ E E+   V++E R  E K 
Sbjct: 1593 R---DEEVEEARQSCQ-------------KKLKQMEVQLEEEYEDKQKVLREKRELEGKL 1636

Query: 1759 KKAITDAAMMAEELKKEQDTSAHLERMKKNLEQT---VKDLQHRLDEAEQLALKGGKKQI 1815
                   A +++++ +    S   +R++K+L++T   + D Q  LD  +  A        
Sbjct: 1637 -------ATLSDQVNRRDFESE--KRLRKDLKRTKALLADAQLMLDHLKNSAPS------ 1681

Query: 1816 QKLEARVRELEGEVENEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQ 1875
               +  + +L+ ++E  +   A AVK  +  E  +++L  Q ++  K    L++ + +LQ
Sbjct: 1682 ---KREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQ 1738

Query: 1876 AKVKSYKRQAEEAEEQSNANLSKFRKLQHELEEAEERADIAESQVNKLRVKSREVH 1931
             +    + + EE +E  N  + K     H+   A+   D+A  Q+N L+ +  E +
Sbjct: 1739 REKNEIQNRLEEDQEDMNELMKK-----HKAAVAQASRDLA--QINDLQAQLEEAN 1787



 Score = 88.2 bits (217), Expect = 7e-17
 Identities = 133/648 (20%), Positives = 277/648 (42%), Gaps = 107/648 (16%)

Query: 1364 LSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQR 1423
            L K++  +   R  +    + R EE         QR ++   ++    A C      +  
Sbjct: 1158 LEKSSCCMGLSRVFFRAGTLARLEE---------QRDEQTSRNLTLFQAACRGYLARQHF 1208

Query: 1424 LQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQ-KYEETQAELEASQKESRSLST 1482
             + +++DL +        C   + K+    K    WK         E++ S+++ R+   
Sbjct: 1209 KKRKIQDLAI-------RCVQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKDE 1261

Query: 1483 ELFKVKNVYEESLDQLETLRRENKNLQQEISDLTEQIA------EGGKQIHELEKIKK-Q 1535
            E+ ++++  E++  +   LR  +  L+  IS+LT ++       E   Q+ + E  ++ +
Sbjct: 1262 EIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDAETAERLR 1321

Query: 1536 VEQEKCEIQAALEEAEASLEHEEGKILRIQL-ELNQVKSEVDRKIAEKDEEIDQLKRNHT 1594
             E+E  E+Q   +  +  +E  E +++  +L    ++  EVD      D+   + +  + 
Sbjct: 1322 AEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVD-----DDDAGGEWRLKYE 1376

Query: 1595 RVVETMQSTLDAEIRSRNDALRV----KKKMEGDLNEMEIQLNHANRLAAESLRNYRNTQ 1650
            R V  +  T     +   D L V    K+++E  L +++     + R   +  +  +   
Sbjct: 1377 RAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLT 1436

Query: 1651 GILKETQLHLDDALRGQEDLKEQLAIVERR--ANLLQAEIEELWATLEQTERSRKIAEQE 1708
              L++T+LHL+    GQ+    +L   +RR  + L QA  E   A  E+ +R +   E++
Sbjct: 1437 AELQDTKLHLE----GQQVRNHELEKKQRRFDSELSQAHEE---AQREKLQREKLQREKD 1489

Query: 1709 LL--DASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVI-QESRNAEE--KAKKAIT 1763
            +L  +A    Q L  ++  +    +K    V  L++E++++  QES++     K KK + 
Sbjct: 1490 MLLAEAFSLKQQLEEKDMDIAGFTQK----VVSLEAELQDISSQESKDEASLAKVKKQLR 1545

Query: 1764 DAAMMA----EELKKEQDTSAHLERMKKNLEQTV--------KDLQHRLDEAEQLALKGG 1811
            D         EEL ++  T   LE+ K  LE  +        K+++ R +E E+ A +  
Sbjct: 1546 DLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEE-ARQSC 1604

Query: 1812 KKQIQKLEARV--------------RELEGEV----ENEQKRNAEAVKGLRKHERRVKEL 1853
            +K+++++E ++              RELEG++    +   +R+ E+ K LRK  +R K L
Sbjct: 1605 QKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKAL 1664

Query: 1854 TYQTE----------EDRKNVLRLQDLVDKLQ----AKVKSYKRQAEEAEE--------- 1890
                +            ++ + +L++ +++ +    A VK+ K    E E+         
Sbjct: 1665 LADAQLMLDHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIA 1724

Query: 1891 -QSNANLSKFRKLQHELEEAEERADIAESQVNKLRVKSREVHTKISAE 1937
                A   +  +LQ E  E + R +  +  +N+L  K +    + S +
Sbjct: 1725 KAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRD 1772


>gi|154354979 myosin X [Homo sapiens]
          Length = 2058

 Score =  495 bits (1275), Expect = e-139
 Identities = 323/965 (33%), Positives = 542/965 (56%), Gaps = 50/965 (5%)

Query: 34  FDAKTSVFVAEPKESYVKSTIQSKEGGKVTVKTEGGATLTVRED-----QVFPMNPPKYD 88
           F   T V++ E  + +  ST+ S   G V  +T+ G   T ++      +V  M+P   +
Sbjct: 5   FTEGTRVWLRENGQHF-PSTVNSCAEGIVVFRTDYGQVFTYKQSTITHQKVTAMHPTNEE 63

Query: 89  KIEDMAMMTHLHEPGVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLP-VYKPEVVAAYRG 147
            ++DMA +T LH   ++YNL +RY    IYTY G    +VNPY+ +  +Y+P  +  Y  
Sbjct: 64  GVDDMASLTELHGGSIMYNLFQRYKRNQIYTYIGSILASVNPYQPIAGLYEPATMEQYSR 123

Query: 148 KKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEK 207
           +   E PPHIF+I++  Y+ +    +NQ ILI+GESGAGKT +TK ++++ + I+   ++
Sbjct: 124 RHLGELPPHIFAIANECYRCLWKRHDNQCILISGESGAGKTESTKLILKFLSVIS---QQ 180

Query: 208 KKDESGKMQGT-LEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADI 266
             + S K + + +E  I+ ++P++EAFGNAKTV N+NSSRFGKF++++    G +    I
Sbjct: 181 SLELSLKEKTSCVERAILESSPIMEAFGNAKTVYNNNSSRFGKFVQLNICQKGNIQGGRI 240

Query: 267 ETYLLEKSRVTFQLKAERSYHIFYQITSNKKPDLIEMLLITTNPYDYAFVSQ-GEITVPS 325
             YLLEK+RV  Q   ER+YHIFY + +  + +  E   ++T P +Y +++Q G +   +
Sbjct: 241 VDYLLEKNRVVRQNPGERNYHIFYALLAGLEHEEREEFYLST-PENYHYLNQSGCVEDKT 299

Query: 326 IDDQEELMATDSAIDILGFTPEEKVSIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVAD 385
           I DQE      +A+D++ F+ EE   + +L   ++H GN++F        A+        
Sbjct: 300 ISDQESFREVITAMDVMQFSKEEVREVSRLLAGILHLGNIEF---ITAGGAQVSFKTALG 356

Query: 386 KAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTVQQVYNAVGALAKAVYEKMFLWMVTR 445
           ++A L  L+   L  AL    + +  E +     VQQ  ++  +LA A+Y   F W++ +
Sbjct: 357 RSAELLGLDPTQLTDALTQRSMFLRGEEILTPLNVQQAVDSRDSLAMALYACCFEWVIKK 416

Query: 446 INQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYK 505
           IN ++   +  +  IG+LDI GFE F+ N  EQ  IN+ NEKLQ++FN H+F LEQ EY 
Sbjct: 417 INSRIKGNEDFK-SIGILDIFGFENFEVNHFEQFNINYANEKLQEYFNKHIFSLEQLEYS 475

Query: 506 KEGIEWTFIDFGMDLAACIELIEKPLGIFSILEEECMFPKATDTSFKNKLYDQHLGKSAN 565
           +EG+ W  ID+ +D   C++LIEK LG+ +++ EE  FP+ATD++   KL+ QH   +  
Sbjct: 476 REGLVWEDIDW-IDNGECLDLIEKKLGLLALINEESHFPQATDSTLLEKLHSQH-ANNHF 533

Query: 566 FQKPKVVKGKAEAHFSLIHYAGTVDYNITGWLDKNKDPLNDTVVGLYQKSAMKTLASLFS 625
           + KP+V    A  +F + HYAG V Y++ G L+KN+D   D ++ L ++S    +  LF 
Sbjct: 534 YVKPRV----AVNNFGVKHYAGEVQYDVRGILEKNRDTFRDDLLNLLRESRFDFIYDLFE 589

Query: 626 TYASAEADSSAKKGAKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPNETKTPG 685
             +S     + K G+K +     TVS+ F+++L+ LM  L S++P FVRCI PN  K P 
Sbjct: 590 HVSSRNNQDTLKCGSKHRR---PTVSSQFKDSLHSLMATLSSSNPFFVRCIKPNMQKMPD 646

Query: 686 AMEHELVLHQLRCNGVLEGIRICRKGFPSRILYGDFKQRYKVLNAS-AIPEGQFIDSKKA 744
             +  +VL+QLR +G+LE +RI + G+  R  + DF +RYKVL  + A+PE    D +  
Sbjct: 647 QFDQAVVLNQLRYSGMLETVRIRKAGYAVRRPFQDFYKRYKVLMRNLALPE----DVRGK 702

Query: 745 SEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDEKLAQIITRTQAVCRGFLMRVEY 804
              LL   D  +++++ G TKVF +  L   LE+ R+E+++      +A   GFL R +Y
Sbjct: 703 CTSLLQLYDASNSEWQLGKTKVFLRESLEQKLEKRREEEVSHAAMVIRAHVLGFLARKQY 762

Query: 805 QKMLQRREALFCIQYNVRAFMNVKHWPWMK----LFFK-IKPLLKSAETEKEMATMKEEF 859
           +K+L     +  IQ N RAF+  + +  +K    +F K ++  +      + +A  +E+ 
Sbjct: 763 RKVLY---CVVIIQKNYRAFLLRRRFLHLKKAAIVFQKQLRGQIARRVYRQLLAEKREQE 819

Query: 860 QKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLADAEERCEQLIKNKIQLE 919
           +K K E    E ++K+ EE+     +E+ + +L+ Q E ++    E    Q    K Q E
Sbjct: 820 EKKKQE----EEEKKKREEEERERERERREAELRAQQEEETRKQQELEALQ----KSQKE 871

Query: 920 AKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVK 979
           A++    E+ +E +++  E+   ++++ED   +  K+  +L LT A ++K +   + +++
Sbjct: 872 AELTRELEKQKENKQVE-EILRLEKEIED--LQRMKEQQELSLTEASLQKLQERRDQELR 928

Query: 980 NLTEE 984
            L EE
Sbjct: 929 RLEEE 933



 Score = 50.1 bits (118), Expect = 2e-05
 Identities = 70/296 (23%), Positives = 133/296 (44%), Gaps = 47/296 (15%)

Query: 857  EEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLADAEERCEQLIKNKI 916
            ++F K    L ++ A  +++  K  +LL+               L DA     QL K K+
Sbjct: 680  QDFYKRYKVLMRNLALPEDVRGKCTSLLQ---------------LYDASNSEWQLGKTKV 724

Query: 917  QLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATEN 976
             L   +++  E+  EEE  +A +  +   L       +K    +   +  ++K   A   
Sbjct: 725  FLRESLEQKLEKRREEEVSHAAMVIRAHVLGFLA---RKQYRKVLYCVVIIQKNYRAFLL 781

Query: 977  KVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDKVNILTKAKTKLEQQVDD 1036
            + + L  + A +   + +     +  +  ++Q L + + +E+K         K E++   
Sbjct: 782  RRRFLHLKKAAI---VFQKQLRGQIARRVYRQLLAEKREQEEK--------KKQEEE--- 827

Query: 1037 LEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQLDEKLEK--KEFEISNLI 1094
                 E++K+   + ER + + E +L+  QE     E  KQQ  E L+K  KE E++  +
Sbjct: 828  -----EKKKREEEERERERERREAELRAQQEE----ETRKQQELEALQKSQKEAELTREL 878

Query: 1095 SKI-EDEQAVEI-QLQKKIKELQARIEELGEEIEAERASRAKAEKQRSDLSRELEE 1148
             K  E++Q  EI +L+K+I++LQ   E+  +E+    AS  K +++R    R LEE
Sbjct: 879  EKQKENKQVEEILRLEKEIEDLQRMKEQ--QELSLTEASLQKLQERRDQELRRLEE 932



 Score = 45.1 bits (105), Expect = 7e-04
 Identities = 45/206 (21%), Positives = 101/206 (49%), Gaps = 22/206 (10%)

Query: 1270 QRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKHQLEEETKAK 1329
            +R+   L A++     E  E  +Q +E+     +  R ++   ++ E L+ Q EEET+ +
Sbjct: 805  RRVYRQLLAEKR----EQEEKKKQEEEEKKKREEEERERERERREAE-LRAQQEEETRKQ 859

Query: 1330 NALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRT-EE 1388
              L  ALQ S+ + +L RE  ++++  + E    L K   ++ + + + E    + + ++
Sbjct: 860  QEL-EALQKSQKEAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQELSLTEASLQK 918

Query: 1389 LEEAKKKLAQRLQE-----AEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACA 1443
            L+E + +  +RL+E     A+E +E++N      ++  + ++N    L +  E S+    
Sbjct: 919  LQERRDQELRRLEEEACRAAQEFLESLN-----FDEIDECVRNIERSLSVGSEFSSELAE 973

Query: 1444 ALDKKQRNFDKVLSEWKQKYEETQAE 1469
            +  +++ NF+     + Q Y E + +
Sbjct: 974  SACEEKPNFN-----FSQPYPEEEVD 994



 Score = 42.7 bits (99), Expect = 0.003
 Identities = 48/232 (20%), Positives = 98/232 (42%), Gaps = 38/232 (16%)

Query: 928  RAEEEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAG 987
            R +    +  +L A+KR+ E++  + +++         K ++E+   E + +    E+  
Sbjct: 800  RGQIARRVYRQLLAEKREQEEKKKQEEEE---------KKKREEEERERERERREAELRA 850

Query: 988  LDETIAKLSKEKKALQETHQQTLDDLQAEEDKVNILTKAKTKLEQQVDDLEGSLEQEK-- 1045
              E   +  +E +ALQ++ ++     + E+ K N   +   +LE++++DL+   EQ++  
Sbjct: 851  QQEEETRKQQELEALQKSQKEAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQELS 910

Query: 1046 KLRMDLERAKRKLEGDLKLAQESTMDMENDKQQLDEKLEKKEF-EISNLISKIEDEQAVE 1104
                 L++ + + + +L+  +E         +   E LE   F EI   +  IE      
Sbjct: 911  LTEASLQKLQERRDQELRRLEEEAC------RAAQEFLESLNFDEIDECVRNIE------ 958

Query: 1105 IQLQKKIKELQARIEELGEEIEAERASRAKAEKQRSDLSREL--EEISERLE 1154
                        R   +G E  +E A  A  EK   + S+    EE+ E  E
Sbjct: 959  ------------RSLSVGSEFSSELAESACEEKPNFNFSQPYPEEEVDEGFE 998



 Score = 42.4 bits (98), Expect = 0.004
 Identities = 30/124 (24%), Positives = 60/124 (48%), Gaps = 9/124 (7%)

Query: 1819 EARVRELEGEVENEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQAKV 1878
            E R +E + + E E+K+  E  +  R+ ERR  EL  Q EE+     R Q  ++ LQ   
Sbjct: 814  EKREQEEKKKQEEEEKKKREEEERERERERREAELRAQQEEE----TRKQQELEALQKSQ 869

Query: 1879 KSYKRQAEEAEEQSNANLSKFRKLQHELEE-----AEERADIAESQVNKLRVKSREVHTK 1933
            K  +   E  +++ N  + +  +L+ E+E+      ++   + E+ + KL+ +  +   +
Sbjct: 870  KEAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQELSLTEASLQKLQERRDQELRR 929

Query: 1934 ISAE 1937
            +  E
Sbjct: 930  LEEE 933



 Score = 42.0 bits (97), Expect = 0.006
 Identities = 46/202 (22%), Positives = 94/202 (46%), Gaps = 27/202 (13%)

Query: 917  QLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATEN 976
            QL A+ +E  E+ ++EEE       +K+K E+E  E +++  + EL   + E+ +   E 
Sbjct: 810  QLLAEKREQEEKKKQEEE-------EKKKREEEERERERERREAELRAQQEEETRKQQEL 862

Query: 977  KVKNLTEEMAGLDETIAKLSKEKKALQE--THQQTLDDLQ--AEEDKVNILTKAKTKLEQ 1032
            +    +++ A L   + K  KE K ++E    ++ ++DLQ   E+ ++++   +  KL++
Sbjct: 863  EALQKSQKEAELTRELEK-QKENKQVEEILRLEKEIEDLQRMKEQQELSLTEASLQKLQE 921

Query: 1033 QVDDLEGSLEQE---------KKLRMD-LERAKRKLEGDLKLAQESTMDMENDKQQLDEK 1082
            + D     LE+E         + L  D ++   R +E  L +  E + ++     +    
Sbjct: 922  RRDQELRRLEEEACRAAQEFLESLNFDEIDECVRNIERSLSVGSEFSSELAESACE---- 977

Query: 1083 LEKKEFEISNLISKIEDEQAVE 1104
             EK  F  S    + E ++  E
Sbjct: 978  -EKPNFNFSQPYPEEEVDEGFE 998



 Score = 41.6 bits (96), Expect = 0.008
 Identities = 78/351 (22%), Positives = 141/351 (40%), Gaps = 52/351 (14%)

Query: 1055 KRKLEGDLKLAQESTMDMENDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKEL 1114
            +++L G +       +  E  +Q+  +K E++E        K  +E+  E + +++  EL
Sbjct: 796  QKQLRGQIARRVYRQLLAEKREQEEKKKQEEEE-------KKKREEEERERERERREAEL 848

Query: 1115 QARIEE---LGEEIEAERASRAKAEKQRSDLSRELEEISE--RLEEAGGATSAQVELNKK 1169
            +A+ EE     +E+EA + S+ +AE     L+RELE+  E  ++EE         +L + 
Sbjct: 849  RAQQEEETRKQQELEALQKSQKEAE-----LTRELEKQKENKQVEEILRLEKEIEDLQRM 903

Query: 1170 R--------EAEFQKL--RRDLEEATLQHEAMVAALRKKHADSMAELGEQIDNLQRVKQK 1219
            +        EA  QKL  RRD E   L+ EA  AA     + +  E+ E + N++R    
Sbjct: 904  KEQQELSLTEASLQKLQERRDQELRRLEEEACRAAQEFLESLNFDEIDECVRNIER---- 959

Query: 1220 LEKEKSELKMETDDLSSNAEAISKAKGNLEKMCRSLEDQVSE--------LKTKEEEQQR 1271
                   L + ++  S  AE+  + K N        E++V E         K      + 
Sbjct: 960  ------SLSVGSEFSSELAESACEEKPNFNFSQPYPEEEVDEGFEADDDAFKDSPNPSEH 1013

Query: 1272 LINDLTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEEL----KHQLEEETK 1327
              +D      R   ++ E    +++     S  + S       +++          E T 
Sbjct: 1014 GHSDQRTSGIRTSDDSSEEDPYMNDTVVPTSPSADSTVLLAPSVQDSGSLHNSSSGESTY 1073

Query: 1328 AKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKY 1378
                 A  L S   D D  ++ YE   +G      +++ +NS  +QW   Y
Sbjct: 1074 CMPQNAGDLPSPDGDYDYDQDDYE---DGAITSGSSVTFSNSYGSQWSPDY 1121



 Score = 38.1 bits (87), Expect = 0.084
 Identities = 39/152 (25%), Positives = 74/152 (48%), Gaps = 17/152 (11%)

Query: 1447 KKQRNFDKVLSEWKQKYEETQ---AELEASQKESRSLSTELFKVKNVYEESLDQLETLRR 1503
            KKQ   +K   E +++  E +   AEL A Q+E      EL  ++   +E+ +    L +
Sbjct: 822  KKQEEEEKKKREEEERERERERREAELRAQQEEETRKQQELEALQKSQKEA-ELTRELEK 880

Query: 1504 ENKNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILR 1563
            + +N Q       E+I    K+I +L+++K+Q  QE    +A+L++ +   E  + ++ R
Sbjct: 881  QKENKQ------VEEILRLEKEIEDLQRMKEQ--QELSLTEASLQKLQ---ERRDQELRR 929

Query: 1564 IQLELNQVKSEVDRKIAEKDEEIDQLKRNHTR 1595
            ++ E  +   E    +    +EID+  RN  R
Sbjct: 930  LEEEACRAAQEFLESL--NFDEIDECVRNIER 959



 Score = 33.1 bits (74), Expect = 2.7
 Identities = 33/102 (32%), Positives = 53/102 (51%), Gaps = 10/102 (9%)

Query: 1530 EKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQL 1589
            E+ KK+ E+E+ E +    EAE   + EE    R Q EL  ++    +K AE   E+++ 
Sbjct: 826  EEEKKKREEEERERERERREAELRAQQEEE--TRKQQELEALQK--SQKEAELTRELEKQ 881

Query: 1590 KRNHTRVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEMEIQ 1631
            K N  +V E ++  L+ EI    D  R+K++ E  L E  +Q
Sbjct: 882  KEN-KQVEEILR--LEKEI---EDLQRMKEQQELSLTEASLQ 917



 Score = 31.6 bits (70), Expect = 7.9
 Identities = 50/226 (22%), Positives = 98/226 (43%), Gaps = 28/226 (12%)

Query: 1715 RVQLLHTQNTSLINTKKKLENDVSQ------LQSEVEEVIQESRNAEEKAKKAITDAAMM 1768
            R + LH +  +++  +K+L   +++      L  + E+  ++ +  EEK K+   +    
Sbjct: 782  RRRFLHLKKAAIV-FQKQLRGQIARRVYRQLLAEKREQEEKKKQEEEEKKKREEEERERE 840

Query: 1769 AEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQ---KLEARVREL 1825
             E  + E       E  K+   + ++  Q   +   +L  +   KQ++   +LE  + +L
Sbjct: 841  RERREAELRAQQEEETRKQQELEALQKSQKEAELTRELEKQKENKQVEEILRLEKEIEDL 900

Query: 1826 EGEVENEQKRNAEAVKGLRK-HERRVKELTYQTEEDRKNVLRLQDLV--DKLQAKVKSYK 1882
            +   E ++    EA   L+K  ERR +EL    EE  +      + +  D++   V++ +
Sbjct: 901  QRMKEQQELSLTEA--SLQKLQERRDQELRRLEEEACRAAQEFLESLNFDEIDECVRNIE 958

Query: 1883 RQ-----------AEEA-EEQSNANLSKFRKLQHELEEAEERADIA 1916
            R            AE A EE+ N N S+    + E++E  E  D A
Sbjct: 959  RSLSVGSEFSSELAESACEEKPNFNFSQ-PYPEEEVDEGFEADDDA 1003



 Score = 31.6 bits (70), Expect = 7.9
 Identities = 32/141 (22%), Positives = 58/141 (41%), Gaps = 14/141 (9%)

Query: 1388 ELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDK 1447
            E EE KK+  +  ++ EE            E+ ++R + E+     +  R      AL K
Sbjct: 817  EQEEKKKQEEEEKKKREEEER---------ERERERREAELRAQQEEETRKQQELEALQK 867

Query: 1448 KQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELFKVKNVYEESLDQLETLRRENKN 1507
             Q+  +      KQK  +   E+   +KE   L     ++K   E SL +  +L++  + 
Sbjct: 868  SQKEAELTRELEKQKENKQVEEILRLEKEIEDLQ----RMKEQQELSLTE-ASLQKLQER 922

Query: 1508 LQQEISDLTEQIAEGGKQIHE 1528
              QE+  L E+     ++  E
Sbjct: 923  RDQELRRLEEEACRAAQEFLE 943


>gi|189083802 myosin VIIA isoform 2 [Homo sapiens]
          Length = 2175

 Score =  482 bits (1241), Expect = e-135
 Identities = 326/922 (35%), Positives = 492/922 (53%), Gaps = 67/922 (7%)

Query: 81  PMNPPKYDKIEDMAMMTHLHEPGVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYKPE 140
           PM+P     +EDM  +  L+E G+L NL  RY   +IYTY+G   V VNPY+ L +Y PE
Sbjct: 58  PMHPTSVHGVEDMIRLGDLNEAGILRNLLIRYRDHLIYTYTGSILVAVNPYQLLSIYSPE 117

Query: 141 VVAAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFAT 200
            +  Y  KK  E PPHIF+I+DN Y  M  +  +Q  +I+GESGAGKT +TK ++Q+ A 
Sbjct: 118 HIRQYTNKKIGEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFLA- 176

Query: 201 IAVTGEKKKDESGKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGK 260
            A++G+            +E Q++ A P+LEAFGNAKT+RNDNSSRFGK+I IHF   G 
Sbjct: 177 -AISGQ---------HSWIEQQVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKRGA 226

Query: 261 LASADIETYLLEKSRVTFQLKAERSYHIFYQITSNKKPDLIEMLLITTNPYDYAFVSQGE 320
           +  A IE YLLEKSRV  Q   ER+YH+FY +      D  + L +     DY +++ G 
Sbjct: 227 IEGAKIEQYLLEKSRVCRQALDERNYHVFYCMLEGMSEDQKKKLGL-GQASDYNYLAMGN 285

Query: 321 -ITVPSIDDQEELMATDSAIDILGFTPEEKVSIYKLTGAVMHYGNMKFKQKQRE--EQAE 377
            IT     D +E     SA+ +L FT  E   I KL  A++H GN++++ +  E  +  E
Sbjct: 286 CITCEGRVDSQEYANIRSAMKVLMFTDTENWEISKLLAAILHLGNLQYEARTFENLDACE 345

Query: 378 PDGTEVADKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTVQQVYNAVGALAKAVYEK 437
              +     AA L  +N  DL+  L    +    E V+   + +Q  +   A  K +Y +
Sbjct: 346 VLFSPSLATAASLLEVNPPDLMSCLTSRTLITRGETVSTPLSREQALDVRDAFVKGIYGR 405

Query: 438 MFLWMVTRINQQL------DTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQF 491
           +F+W+V +IN  +      D K  R+  IG+LDI GFE F  NS EQLCINF NE LQQF
Sbjct: 406 LFVWIVDKINAAIYKPPSQDVKNSRR-SIGLLDIFGFENFAVNSFEQLCINFANEHLQQF 464

Query: 492 FNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPLGIFSILEEECMFPKATDTSF 551
           F  H+F LEQEEY  E I+W  I+F  +  A   +  KP+ I S+++EE  FPK TDT+ 
Sbjct: 465 FVRHVFKLEQEEYDLESIDWLHIEFTDNQDALDMIANKPMNIISLIDEESKFPKGTDTTM 524

Query: 552 KNKLYDQHLGKSANFQKPKVVKGKAEAHFSLIHYAGTVDYNITGWLDKNKDPLNDTVVGL 611
            +KL  QH   +AN+  P   K   E  F + H+AG V Y   G+L+KN+D L+  ++ L
Sbjct: 525 LHKLNSQH-KLNANYIPP---KNNHETQFGINHFAGIVYYETQGFLEKNRDTLHGDIIQL 580

Query: 612 YQKSAMKTLASLFSTYASAEADSSAKKGAKKKGSSFQTVSALFRENLNKLMTNLRSTHPH 671
              S  K +  +F      +AD +     +K+     T+S+ F+ +L  LM  L +  P 
Sbjct: 581 VHSSRNKFIKQIF------QADVAMGAETRKRS---PTLSSQFKRSLELLMRTLGACQPF 631

Query: 672 FVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYGDFKQRYKVLNAS 731
           FVRCI PNE K P   +  L + QLR +G++E IRI R G+P R  + +F +RY+VL   
Sbjct: 632 FVRCIKPNEFKKPMLFDRHLCVRQLRYSGMMETIRIRRAGYPIRYSFVEFVERYRVLLPG 691

Query: 732 AIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDEKLAQIITRT 791
             P  +  D +   +++  ++   H  ++ G TK+F K     LLE  RD+ +   +   
Sbjct: 692 VKPAYKQGDLRGTCQRMAEAVLGTHDDWQIGKTKIFLKDHHDMLLEVERDKAITDRVILL 751

Query: 792 QAVCRGFLMRVEYQKMLQRREALFCIQYNVRAFMNVKHWPWMKL-FFKIKPLLKSAETEK 850
           Q V RGF  R  + K+   + A   IQ + R     K++  M+L F +++ L +S +   
Sbjct: 752 QKVIRGFKDRSNFLKL---KNAATLIQRHWRGHNCRKNYGLMRLGFLRLQALHRSRK--- 805

Query: 851 EMATMKEEFQKTKDELAKSEAK-RKELEEKMVTLLKEKNDLQLQVQSEADSLADAEERCE 909
               + ++++  +  + + +A+ R  L  K     + +    L VQ+ A  +     R  
Sbjct: 806 ----LHQQYRLARQRIIQFQARCRAYLVRK---AFRHRLWAVLTVQAYARGM--IARRLH 856

Query: 910 QLIKNKIQLEAKIKEVTERAEEEEEINAELTAKK------RKLEDECSELKKDIDDLELT 963
           Q ++ +     + +++  R  EEE++  E++AKK      RK ++  ++L ++  + EL 
Sbjct: 857 QRLRAEYLWRLEAEKM--RLAEEEKLRKEMSAKKAKEEAERKHQERLAQLAREDAEREL- 913

Query: 964 LAKVEKEKHATENKVKNLTEEM 985
                KEK A   K K L E+M
Sbjct: 914 -----KEKEAARRK-KELLEQM 929



 Score = 32.3 bits (72), Expect = 4.6
 Identities = 23/79 (29%), Positives = 43/79 (54%), Gaps = 6/79 (7%)

Query: 1802 EAEQLALKGGKKQIQKLEARVRELEGEVENEQK----RNAEAVKGLRKHE--RRVKELTY 1855
            EAE++ L   +K  +++ A+  + E E +++++       +A + L++ E  RR KEL  
Sbjct: 868  EAEKMRLAEEEKLRKEMSAKKAKEEAERKHQERLAQLAREDAERELKEKEAARRKKELLE 927

Query: 1856 QTEEDRKNVLRLQDLVDKL 1874
            Q E  R   +   D+VDK+
Sbjct: 928  QMERARHEPVNHSDMVDKM 946


>gi|189083800 myosin VIIA isoform 3 [Homo sapiens]
          Length = 1204

 Score =  482 bits (1241), Expect = e-135
 Identities = 326/922 (35%), Positives = 492/922 (53%), Gaps = 67/922 (7%)

Query: 81  PMNPPKYDKIEDMAMMTHLHEPGVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYKPE 140
           PM+P     +EDM  +  L+E G+L NL  RY   +IYTY+G   V VNPY+ L +Y PE
Sbjct: 58  PMHPTSVHGVEDMIRLGDLNEAGILRNLLIRYRDHLIYTYTGSILVAVNPYQLLSIYSPE 117

Query: 141 VVAAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFAT 200
            +  Y  KK  E PPHIF+I+DN Y  M  +  +Q  +I+GESGAGKT +TK ++Q+ A 
Sbjct: 118 HIRQYTNKKIGEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFLA- 176

Query: 201 IAVTGEKKKDESGKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGK 260
            A++G+            +E Q++ A P+LEAFGNAKT+RNDNSSRFGK+I IHF   G 
Sbjct: 177 -AISGQ---------HSWIEQQVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKRGA 226

Query: 261 LASADIETYLLEKSRVTFQLKAERSYHIFYQITSNKKPDLIEMLLITTNPYDYAFVSQGE 320
           +  A IE YLLEKSRV  Q   ER+YH+FY +      D  + L +     DY +++ G 
Sbjct: 227 IEGAKIEQYLLEKSRVCRQALDERNYHVFYCMLEGMSEDQKKKLGL-GQASDYNYLAMGN 285

Query: 321 -ITVPSIDDQEELMATDSAIDILGFTPEEKVSIYKLTGAVMHYGNMKFKQKQRE--EQAE 377
            IT     D +E     SA+ +L FT  E   I KL  A++H GN++++ +  E  +  E
Sbjct: 286 CITCEGRVDSQEYANIRSAMKVLMFTDTENWEISKLLAAILHLGNLQYEARTFENLDACE 345

Query: 378 PDGTEVADKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTVQQVYNAVGALAKAVYEK 437
              +     AA L  +N  DL+  L    +    E V+   + +Q  +   A  K +Y +
Sbjct: 346 VLFSPSLATAASLLEVNPPDLMSCLTSRTLITRGETVSTPLSREQALDVRDAFVKGIYGR 405

Query: 438 MFLWMVTRINQQL------DTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQF 491
           +F+W+V +IN  +      D K  R+  IG+LDI GFE F  NS EQLCINF NE LQQF
Sbjct: 406 LFVWIVDKINAAIYKPPSQDVKNSRR-SIGLLDIFGFENFAVNSFEQLCINFANEHLQQF 464

Query: 492 FNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPLGIFSILEEECMFPKATDTSF 551
           F  H+F LEQEEY  E I+W  I+F  +  A   +  KP+ I S+++EE  FPK TDT+ 
Sbjct: 465 FVRHVFKLEQEEYDLESIDWLHIEFTDNQDALDMIANKPMNIISLIDEESKFPKGTDTTM 524

Query: 552 KNKLYDQHLGKSANFQKPKVVKGKAEAHFSLIHYAGTVDYNITGWLDKNKDPLNDTVVGL 611
            +KL  QH   +AN+  P   K   E  F + H+AG V Y   G+L+KN+D L+  ++ L
Sbjct: 525 LHKLNSQH-KLNANYIPP---KNNHETQFGINHFAGIVYYETQGFLEKNRDTLHGDIIQL 580

Query: 612 YQKSAMKTLASLFSTYASAEADSSAKKGAKKKGSSFQTVSALFRENLNKLMTNLRSTHPH 671
              S  K +  +F      +AD +     +K+     T+S+ F+ +L  LM  L +  P 
Sbjct: 581 VHSSRNKFIKQIF------QADVAMGAETRKRS---PTLSSQFKRSLELLMRTLGACQPF 631

Query: 672 FVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYGDFKQRYKVLNAS 731
           FVRCI PNE K P   +  L + QLR +G++E IRI R G+P R  + +F +RY+VL   
Sbjct: 632 FVRCIKPNEFKKPMLFDRHLCVRQLRYSGMMETIRIRRAGYPIRYSFVEFVERYRVLLPG 691

Query: 732 AIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDEKLAQIITRT 791
             P  +  D +   +++  ++   H  ++ G TK+F K     LLE  RD+ +   +   
Sbjct: 692 VKPAYKQGDLRGTCQRMAEAVLGTHDDWQIGKTKIFLKDHHDMLLEVERDKAITDRVILL 751

Query: 792 QAVCRGFLMRVEYQKMLQRREALFCIQYNVRAFMNVKHWPWMKL-FFKIKPLLKSAETEK 850
           Q V RGF  R  + K+   + A   IQ + R     K++  M+L F +++ L +S +   
Sbjct: 752 QKVIRGFKDRSNFLKL---KNAATLIQRHWRGHNCRKNYGLMRLGFLRLQALHRSRK--- 805

Query: 851 EMATMKEEFQKTKDELAKSEAK-RKELEEKMVTLLKEKNDLQLQVQSEADSLADAEERCE 909
               + ++++  +  + + +A+ R  L  K     + +    L VQ+ A  +     R  
Sbjct: 806 ----LHQQYRLARQRIIQFQARCRAYLVRK---AFRHRLWAVLTVQAYARGM--IARRLH 856

Query: 910 QLIKNKIQLEAKIKEVTERAEEEEEINAELTAKK------RKLEDECSELKKDIDDLELT 963
           Q ++ +     + +++  R  EEE++  E++AKK      RK ++  ++L ++  + EL 
Sbjct: 857 QRLRAEYLWRLEAEKM--RLAEEEKLRKEMSAKKAKEEAERKHQERLAQLAREDAEREL- 913

Query: 964 LAKVEKEKHATENKVKNLTEEM 985
                KEK A   K K L E+M
Sbjct: 914 -----KEKEAARRK-KELLEQM 929



 Score = 32.3 bits (72), Expect = 4.6
 Identities = 23/79 (29%), Positives = 43/79 (54%), Gaps = 6/79 (7%)

Query: 1802 EAEQLALKGGKKQIQKLEARVRELEGEVENEQK----RNAEAVKGLRKHE--RRVKELTY 1855
            EAE++ L   +K  +++ A+  + E E +++++       +A + L++ E  RR KEL  
Sbjct: 868  EAEKMRLAEEEKLRKEMSAKKAKEEAERKHQERLAQLAREDAERELKEKEAARRKKELLE 927

Query: 1856 QTEEDRKNVLRLQDLVDKL 1874
            Q E  R   +   D+VDK+
Sbjct: 928  QMERARHEPVNHSDMVDKM 946


>gi|189083798 myosin VIIA isoform 1 [Homo sapiens]
          Length = 2215

 Score =  482 bits (1241), Expect = e-135
 Identities = 326/922 (35%), Positives = 492/922 (53%), Gaps = 67/922 (7%)

Query: 81  PMNPPKYDKIEDMAMMTHLHEPGVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYKPE 140
           PM+P     +EDM  +  L+E G+L NL  RY   +IYTY+G   V VNPY+ L +Y PE
Sbjct: 58  PMHPTSVHGVEDMIRLGDLNEAGILRNLLIRYRDHLIYTYTGSILVAVNPYQLLSIYSPE 117

Query: 141 VVAAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFAT 200
            +  Y  KK  E PPHIF+I+DN Y  M  +  +Q  +I+GESGAGKT +TK ++Q+ A 
Sbjct: 118 HIRQYTNKKIGEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFLA- 176

Query: 201 IAVTGEKKKDESGKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGK 260
            A++G+            +E Q++ A P+LEAFGNAKT+RNDNSSRFGK+I IHF   G 
Sbjct: 177 -AISGQ---------HSWIEQQVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKRGA 226

Query: 261 LASADIETYLLEKSRVTFQLKAERSYHIFYQITSNKKPDLIEMLLITTNPYDYAFVSQGE 320
           +  A IE YLLEKSRV  Q   ER+YH+FY +      D  + L +     DY +++ G 
Sbjct: 227 IEGAKIEQYLLEKSRVCRQALDERNYHVFYCMLEGMSEDQKKKLGL-GQASDYNYLAMGN 285

Query: 321 -ITVPSIDDQEELMATDSAIDILGFTPEEKVSIYKLTGAVMHYGNMKFKQKQRE--EQAE 377
            IT     D +E     SA+ +L FT  E   I KL  A++H GN++++ +  E  +  E
Sbjct: 286 CITCEGRVDSQEYANIRSAMKVLMFTDTENWEISKLLAAILHLGNLQYEARTFENLDACE 345

Query: 378 PDGTEVADKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTVQQVYNAVGALAKAVYEK 437
              +     AA L  +N  DL+  L    +    E V+   + +Q  +   A  K +Y +
Sbjct: 346 VLFSPSLATAASLLEVNPPDLMSCLTSRTLITRGETVSTPLSREQALDVRDAFVKGIYGR 405

Query: 438 MFLWMVTRINQQL------DTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQF 491
           +F+W+V +IN  +      D K  R+  IG+LDI GFE F  NS EQLCINF NE LQQF
Sbjct: 406 LFVWIVDKINAAIYKPPSQDVKNSRR-SIGLLDIFGFENFAVNSFEQLCINFANEHLQQF 464

Query: 492 FNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPLGIFSILEEECMFPKATDTSF 551
           F  H+F LEQEEY  E I+W  I+F  +  A   +  KP+ I S+++EE  FPK TDT+ 
Sbjct: 465 FVRHVFKLEQEEYDLESIDWLHIEFTDNQDALDMIANKPMNIISLIDEESKFPKGTDTTM 524

Query: 552 KNKLYDQHLGKSANFQKPKVVKGKAEAHFSLIHYAGTVDYNITGWLDKNKDPLNDTVVGL 611
            +KL  QH   +AN+  P   K   E  F + H+AG V Y   G+L+KN+D L+  ++ L
Sbjct: 525 LHKLNSQH-KLNANYIPP---KNNHETQFGINHFAGIVYYETQGFLEKNRDTLHGDIIQL 580

Query: 612 YQKSAMKTLASLFSTYASAEADSSAKKGAKKKGSSFQTVSALFRENLNKLMTNLRSTHPH 671
              S  K +  +F      +AD +     +K+     T+S+ F+ +L  LM  L +  P 
Sbjct: 581 VHSSRNKFIKQIF------QADVAMGAETRKRS---PTLSSQFKRSLELLMRTLGACQPF 631

Query: 672 FVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYGDFKQRYKVLNAS 731
           FVRCI PNE K P   +  L + QLR +G++E IRI R G+P R  + +F +RY+VL   
Sbjct: 632 FVRCIKPNEFKKPMLFDRHLCVRQLRYSGMMETIRIRRAGYPIRYSFVEFVERYRVLLPG 691

Query: 732 AIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDEKLAQIITRT 791
             P  +  D +   +++  ++   H  ++ G TK+F K     LLE  RD+ +   +   
Sbjct: 692 VKPAYKQGDLRGTCQRMAEAVLGTHDDWQIGKTKIFLKDHHDMLLEVERDKAITDRVILL 751

Query: 792 QAVCRGFLMRVEYQKMLQRREALFCIQYNVRAFMNVKHWPWMKL-FFKIKPLLKSAETEK 850
           Q V RGF  R  + K+   + A   IQ + R     K++  M+L F +++ L +S +   
Sbjct: 752 QKVIRGFKDRSNFLKL---KNAATLIQRHWRGHNCRKNYGLMRLGFLRLQALHRSRK--- 805

Query: 851 EMATMKEEFQKTKDELAKSEAK-RKELEEKMVTLLKEKNDLQLQVQSEADSLADAEERCE 909
               + ++++  +  + + +A+ R  L  K     + +    L VQ+ A  +     R  
Sbjct: 806 ----LHQQYRLARQRIIQFQARCRAYLVRK---AFRHRLWAVLTVQAYARGM--IARRLH 856

Query: 910 QLIKNKIQLEAKIKEVTERAEEEEEINAELTAKK------RKLEDECSELKKDIDDLELT 963
           Q ++ +     + +++  R  EEE++  E++AKK      RK ++  ++L ++  + EL 
Sbjct: 857 QRLRAEYLWRLEAEKM--RLAEEEKLRKEMSAKKAKEEAERKHQERLAQLAREDAEREL- 913

Query: 964 LAKVEKEKHATENKVKNLTEEM 985
                KEK A   K K L E+M
Sbjct: 914 -----KEKEAARRK-KELLEQM 929



 Score = 32.3 bits (72), Expect = 4.6
 Identities = 23/79 (29%), Positives = 43/79 (54%), Gaps = 6/79 (7%)

Query: 1802 EAEQLALKGGKKQIQKLEARVRELEGEVENEQK----RNAEAVKGLRKHE--RRVKELTY 1855
            EAE++ L   +K  +++ A+  + E E +++++       +A + L++ E  RR KEL  
Sbjct: 868  EAEKMRLAEEEKLRKEMSAKKAKEEAERKHQERLAQLAREDAERELKEKEAARRKKELLE 927

Query: 1856 QTEEDRKNVLRLQDLVDKL 1874
            Q E  R   +   D+VDK+
Sbjct: 928  QMERARHEPVNHSDMVDKM 946


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.127    0.336 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 63,154,437
Number of Sequences: 37866
Number of extensions: 2867741
Number of successful extensions: 63189
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 830
Number of HSP's successfully gapped in prelim test: 1644
Number of HSP's that attempted gapping in prelim test: 13671
Number of HSP's gapped (non-prelim): 16688
length of query: 1937
length of database: 18,247,518
effective HSP length: 117
effective length of query: 1820
effective length of database: 13,817,196
effective search space: 25147296720
effective search space used: 25147296720
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 70 (31.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.