BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo sapiens] (1941 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo... 3751 0.0 gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo... 3751 0.0 gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo... 3588 0.0 gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [... 3513 0.0 gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo ... 3498 0.0 gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H... 3231 0.0 gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo... 3146 0.0 gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s... 3137 0.0 gi|156104908 myosin heavy chain 6 [Homo sapiens] 3108 0.0 gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta ... 2609 0.0 gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens] 2318 0.0 gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 1423 0.0 gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 1423 0.0 gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 1423 0.0 gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 1423 0.0 gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 1413 0.0 gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 1410 0.0 gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens] 1306 0.0 gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens] 1305 0.0 gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens] 1293 0.0 gi|153945715 myosin VC [Homo sapiens] 608 e-173 gi|215982794 myosin VA isoform 2 [Homo sapiens] 597 e-170 gi|215982791 myosin VA isoform 1 [Homo sapiens] 594 e-169 gi|122937345 myosin VB [Homo sapiens] 564 e-160 gi|28416946 myosin 18A isoform a [Homo sapiens] 509 e-143 gi|42794779 myosin 18A isoform b [Homo sapiens] 506 e-143 gi|154354979 myosin X [Homo sapiens] 491 e-138 gi|189083802 myosin VIIA isoform 2 [Homo sapiens] 481 e-135 gi|189083800 myosin VIIA isoform 3 [Homo sapiens] 481 e-135 gi|189083798 myosin VIIA isoform 1 [Homo sapiens] 481 e-135 >gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo sapiens] Length = 1941 Score = 3751 bits (9726), Expect = 0.0 Identities = 1941/1941 (100%), Positives = 1941/1941 (100%) Query: 1 MSSDSELAVFGEAAPFLRKSERERIEAQNRPFDAKTSVFVAEPKESFVKGTIQSREGGKV 60 MSSDSELAVFGEAAPFLRKSERERIEAQNRPFDAKTSVFVAEPKESFVKGTIQSREGGKV Sbjct: 1 MSSDSELAVFGEAAPFLRKSERERIEAQNRPFDAKTSVFVAEPKESFVKGTIQSREGGKV 60 Query: 61 TVKTEGGATLTVKDDQVFPMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSG 120 TVKTEGGATLTVKDDQVFPMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSG Sbjct: 61 TVKTEGGATLTVKDDQVFPMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSG 120 Query: 121 LFCVTVNPYKWLPVYKPEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGE 180 LFCVTVNPYKWLPVYKPEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGE Sbjct: 121 LFCVTVNPYKWLPVYKPEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGE 180 Query: 181 SGAGKTVNTKRVIQYFATIAVTGEKKKEEITSGKIQGTLEDQIISANPLLEAFGNAKTVR 240 SGAGKTVNTKRVIQYFATIAVTGEKKKEEITSGKIQGTLEDQIISANPLLEAFGNAKTVR Sbjct: 181 SGAGKTVNTKRVIQYFATIAVTGEKKKEEITSGKIQGTLEDQIISANPLLEAFGNAKTVR 240 Query: 241 NDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVVFQLKAERSYHIFYQITSNKKPEL 300 NDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVVFQLKAERSYHIFYQITSNKKPEL Sbjct: 241 NDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVVFQLKAERSYHIFYQITSNKKPEL 300 Query: 301 IEMLLITTNPYDYPFVSQGEISVASIDDQEELMATDSAIDILGFTNEEKVSIYKLTGAVM 360 IEMLLITTNPYDYPFVSQGEISVASIDDQEELMATDSAIDILGFTNEEKVSIYKLTGAVM Sbjct: 301 IEMLLITTNPYDYPFVSQGEISVASIDDQEELMATDSAIDILGFTNEEKVSIYKLTGAVM 360 Query: 361 HYGNLKFKQKQREEQAEPDGTEVADKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTV 420 HYGNLKFKQKQREEQAEPDGTEVADKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTV Sbjct: 361 HYGNLKFKQKQREEQAEPDGTEVADKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTV 420 Query: 421 EQVSNAVGALAKAVYEKMFLWMVARINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLC 480 EQVSNAVGALAKAVYEKMFLWMVARINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLC Sbjct: 421 EQVSNAVGALAKAVYEKMFLWMVARINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLC 480 Query: 481 INFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEE 540 INFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEE Sbjct: 481 INFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEE 540 Query: 541 CMFPKATDTSFKNKLYDQHLGKSANFQKPKVVKGKAEAHFALIHYAGVVDYNITGWLEKN 600 CMFPKATDTSFKNKLYDQHLGKSANFQKPKVVKGKAEAHFALIHYAGVVDYNITGWLEKN Sbjct: 541 CMFPKATDTSFKNKLYDQHLGKSANFQKPKVVKGKAEAHFALIHYAGVVDYNITGWLEKN 600 Query: 601 KDPLNETVVGLYQKSAMKTLAQLFSGAQTAEGEGAGGGAKKGGKKKGSSFQTVSALFREN 660 KDPLNETVVGLYQKSAMKTLAQLFSGAQTAEGEGAGGGAKKGGKKKGSSFQTVSALFREN Sbjct: 601 KDPLNETVVGLYQKSAMKTLAQLFSGAQTAEGEGAGGGAKKGGKKKGSSFQTVSALFREN 660 Query: 661 LNKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRIL 720 LNKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRIL Sbjct: 661 LNKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRIL 720 Query: 721 YADFKQRYKVLNASAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLE 780 YADFKQRYKVLNASAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLE Sbjct: 721 YADFKQRYKVLNASAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLE 780 Query: 781 EMRDDKLAQLITRTQARCRGFLARVEYQRMVERREAIFCIQYNIRSFMNVKHWPWMKLFF 840 EMRDDKLAQLITRTQARCRGFLARVEYQRMVERREAIFCIQYNIRSFMNVKHWPWMKLFF Sbjct: 781 EMRDDKLAQLITRTQARCRGFLARVEYQRMVERREAIFCIQYNIRSFMNVKHWPWMKLFF 840 Query: 841 KIKPLLKSAETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAE 900 KIKPLLKSAETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAE Sbjct: 841 KIKPLLKSAETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAE 900 Query: 901 AEGLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDI 960 AEGLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDI Sbjct: 901 AEGLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDI 960 Query: 961 DDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEE 1020 DDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEE Sbjct: 961 DDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEE 1020 Query: 1021 DKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQ 1080 DKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQ Sbjct: 1021 DKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQ 1080 Query: 1081 QLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEK 1140 QLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEK Sbjct: 1081 QLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEK 1140 Query: 1141 QRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRK 1200 QRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRK Sbjct: 1141 QRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRK 1200 Query: 1201 KHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLED 1260 KHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLED Sbjct: 1201 KHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLED 1260 Query: 1261 QLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEE 1320 QLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEE Sbjct: 1261 QLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEE 1320 Query: 1321 LKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTK 1380 LKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTK Sbjct: 1321 LKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTK 1380 Query: 1381 YETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVER 1440 YETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVER Sbjct: 1381 YETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVER 1440 Query: 1441 TNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQ 1500 TNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQ Sbjct: 1441 TNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQ 1500 Query: 1501 LETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHE 1560 LETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHE Sbjct: 1501 LETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHE 1560 Query: 1561 EGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRL 1620 EGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRL Sbjct: 1561 EGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRL 1620 Query: 1621 KKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMV 1680 KKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMV Sbjct: 1621 KKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMV 1680 Query: 1681 ERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDI 1740 ERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDI Sbjct: 1681 ERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDI 1740 Query: 1741 SQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQ 1800 SQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQ Sbjct: 1741 SQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQ 1800 Query: 1801 LRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQT 1860 LRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQT Sbjct: 1801 LRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQT 1860 Query: 1861 EEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAE 1920 EEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAE Sbjct: 1861 EEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAE 1920 Query: 1921 SQVNKLRVKSREVHTKVISEE 1941 SQVNKLRVKSREVHTKVISEE Sbjct: 1921 SQVNKLRVKSREVHTKVISEE 1941 >gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo sapiens] Length = 1941 Score = 3751 bits (9726), Expect = 0.0 Identities = 1941/1941 (100%), Positives = 1941/1941 (100%) Query: 1 MSSDSELAVFGEAAPFLRKSERERIEAQNRPFDAKTSVFVAEPKESFVKGTIQSREGGKV 60 MSSDSELAVFGEAAPFLRKSERERIEAQNRPFDAKTSVFVAEPKESFVKGTIQSREGGKV Sbjct: 1 MSSDSELAVFGEAAPFLRKSERERIEAQNRPFDAKTSVFVAEPKESFVKGTIQSREGGKV 60 Query: 61 TVKTEGGATLTVKDDQVFPMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSG 120 TVKTEGGATLTVKDDQVFPMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSG Sbjct: 61 TVKTEGGATLTVKDDQVFPMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSG 120 Query: 121 LFCVTVNPYKWLPVYKPEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGE 180 LFCVTVNPYKWLPVYKPEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGE Sbjct: 121 LFCVTVNPYKWLPVYKPEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGE 180 Query: 181 SGAGKTVNTKRVIQYFATIAVTGEKKKEEITSGKIQGTLEDQIISANPLLEAFGNAKTVR 240 SGAGKTVNTKRVIQYFATIAVTGEKKKEEITSGKIQGTLEDQIISANPLLEAFGNAKTVR Sbjct: 181 SGAGKTVNTKRVIQYFATIAVTGEKKKEEITSGKIQGTLEDQIISANPLLEAFGNAKTVR 240 Query: 241 NDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVVFQLKAERSYHIFYQITSNKKPEL 300 NDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVVFQLKAERSYHIFYQITSNKKPEL Sbjct: 241 NDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVVFQLKAERSYHIFYQITSNKKPEL 300 Query: 301 IEMLLITTNPYDYPFVSQGEISVASIDDQEELMATDSAIDILGFTNEEKVSIYKLTGAVM 360 IEMLLITTNPYDYPFVSQGEISVASIDDQEELMATDSAIDILGFTNEEKVSIYKLTGAVM Sbjct: 301 IEMLLITTNPYDYPFVSQGEISVASIDDQEELMATDSAIDILGFTNEEKVSIYKLTGAVM 360 Query: 361 HYGNLKFKQKQREEQAEPDGTEVADKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTV 420 HYGNLKFKQKQREEQAEPDGTEVADKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTV Sbjct: 361 HYGNLKFKQKQREEQAEPDGTEVADKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTV 420 Query: 421 EQVSNAVGALAKAVYEKMFLWMVARINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLC 480 EQVSNAVGALAKAVYEKMFLWMVARINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLC Sbjct: 421 EQVSNAVGALAKAVYEKMFLWMVARINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLC 480 Query: 481 INFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEE 540 INFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEE Sbjct: 481 INFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEE 540 Query: 541 CMFPKATDTSFKNKLYDQHLGKSANFQKPKVVKGKAEAHFALIHYAGVVDYNITGWLEKN 600 CMFPKATDTSFKNKLYDQHLGKSANFQKPKVVKGKAEAHFALIHYAGVVDYNITGWLEKN Sbjct: 541 CMFPKATDTSFKNKLYDQHLGKSANFQKPKVVKGKAEAHFALIHYAGVVDYNITGWLEKN 600 Query: 601 KDPLNETVVGLYQKSAMKTLAQLFSGAQTAEGEGAGGGAKKGGKKKGSSFQTVSALFREN 660 KDPLNETVVGLYQKSAMKTLAQLFSGAQTAEGEGAGGGAKKGGKKKGSSFQTVSALFREN Sbjct: 601 KDPLNETVVGLYQKSAMKTLAQLFSGAQTAEGEGAGGGAKKGGKKKGSSFQTVSALFREN 660 Query: 661 LNKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRIL 720 LNKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRIL Sbjct: 661 LNKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRIL 720 Query: 721 YADFKQRYKVLNASAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLE 780 YADFKQRYKVLNASAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLE Sbjct: 721 YADFKQRYKVLNASAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLE 780 Query: 781 EMRDDKLAQLITRTQARCRGFLARVEYQRMVERREAIFCIQYNIRSFMNVKHWPWMKLFF 840 EMRDDKLAQLITRTQARCRGFLARVEYQRMVERREAIFCIQYNIRSFMNVKHWPWMKLFF Sbjct: 781 EMRDDKLAQLITRTQARCRGFLARVEYQRMVERREAIFCIQYNIRSFMNVKHWPWMKLFF 840 Query: 841 KIKPLLKSAETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAE 900 KIKPLLKSAETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAE Sbjct: 841 KIKPLLKSAETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAE 900 Query: 901 AEGLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDI 960 AEGLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDI Sbjct: 901 AEGLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDI 960 Query: 961 DDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEE 1020 DDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEE Sbjct: 961 DDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEE 1020 Query: 1021 DKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQ 1080 DKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQ Sbjct: 1021 DKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQ 1080 Query: 1081 QLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEK 1140 QLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEK Sbjct: 1081 QLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEK 1140 Query: 1141 QRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRK 1200 QRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRK Sbjct: 1141 QRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRK 1200 Query: 1201 KHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLED 1260 KHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLED Sbjct: 1201 KHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLED 1260 Query: 1261 QLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEE 1320 QLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEE Sbjct: 1261 QLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEE 1320 Query: 1321 LKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTK 1380 LKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTK Sbjct: 1321 LKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTK 1380 Query: 1381 YETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVER 1440 YETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVER Sbjct: 1381 YETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVER 1440 Query: 1441 TNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQ 1500 TNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQ Sbjct: 1441 TNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQ 1500 Query: 1501 LETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHE 1560 LETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHE Sbjct: 1501 LETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHE 1560 Query: 1561 EGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRL 1620 EGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRL Sbjct: 1561 EGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRL 1620 Query: 1621 KKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMV 1680 KKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMV Sbjct: 1621 KKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMV 1680 Query: 1681 ERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDI 1740 ERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDI Sbjct: 1681 ERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDI 1740 Query: 1741 SQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQ 1800 SQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQ Sbjct: 1741 SQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQ 1800 Query: 1801 LRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQT 1860 LRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQT Sbjct: 1801 LRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQT 1860 Query: 1861 EEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAE 1920 EEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAE Sbjct: 1861 EEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAE 1920 Query: 1921 SQVNKLRVKSREVHTKVISEE 1941 SQVNKLRVKSREVHTKVISEE Sbjct: 1921 SQVNKLRVKSREVHTKVISEE 1941 >gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo sapiens] Length = 1939 Score = 3588 bits (9305), Expect = 0.0 Identities = 1839/1941 (94%), Positives = 1897/1941 (97%), Gaps = 2/1941 (0%) Query: 1 MSSDSELAVFGEAAPFLRKSERERIEAQNRPFDAKTSVFVAEPKESFVKGTIQSREGGKV 60 MSSDSE+A+FGEAAPFLRKSERERIEAQN+PFDAKTSVFV +PKESFVK T+QSREGGKV Sbjct: 1 MSSDSEMAIFGEAAPFLRKSERERIEAQNKPFDAKTSVFVVDPKESFVKATVQSREGGKV 60 Query: 61 TVKTEGGATLTVKDDQVFPMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSG 120 T KTE GAT+TVKDDQVFPMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSG Sbjct: 61 TAKTEAGATVTVKDDQVFPMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSG 120 Query: 121 LFCVTVNPYKWLPVYKPEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGE 180 LFCVTVNPYKWLPVY EVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGE Sbjct: 121 LFCVTVNPYKWLPVYNAEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGE 180 Query: 181 SGAGKTVNTKRVIQYFATIAVTGEKKKEEITSGKIQGTLEDQIISANPLLEAFGNAKTVR 240 SGAGKTVNTKRVIQYFATIAVTGEKKKEE+TSGK+QGTLEDQIISANPLLEAFGNAKTVR Sbjct: 181 SGAGKTVNTKRVIQYFATIAVTGEKKKEEVTSGKMQGTLEDQIISANPLLEAFGNAKTVR 240 Query: 241 NDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVVFQLKAERSYHIFYQITSNKKPEL 300 NDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRV FQLKAERSYHIFYQI SNKKP+L Sbjct: 241 NDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQIMSNKKPDL 300 Query: 301 IEMLLITTNPYDYPFVSQGEISVASIDDQEELMATDSAIDILGFTNEEKVSIYKLTGAVM 360 IEMLLITTNPYDY FVSQGEI+V SIDDQEELMATDSAI+ILGFT++E+VSIYKLTGAVM Sbjct: 301 IEMLLITTNPYDYAFVSQGEITVPSIDDQEELMATDSAIEILGFTSDERVSIYKLTGAVM 360 Query: 361 HYGNLKFKQKQREEQAEPDGTEVADKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTV 420 HYGN+KFKQKQREEQAEPDGTEVADKAAYLQ+LNSADLLKALCYPRVKVGNEYVTKGQTV Sbjct: 361 HYGNMKFKQKQREEQAEPDGTEVADKAAYLQNLNSADLLKALCYPRVKVGNEYVTKGQTV 420 Query: 421 EQVSNAVGALAKAVYEKMFLWMVARINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLC 480 +QV NAVGALAKAVY+KMFLWMV RINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLC Sbjct: 421 QQVYNAVGALAKAVYDKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLC 480 Query: 481 INFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEE 540 INFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEE Sbjct: 481 INFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEE 540 Query: 541 CMFPKATDTSFKNKLYDQHLGKSANFQKPKVVKGKAEAHFALIHYAGVVDYNITGWLEKN 600 CMFPKATDTSFKNKLY+QHLGKS NFQKPK KGK EAHF+LIHYAG VDYNI GWL+KN Sbjct: 541 CMFPKATDTSFKNKLYEQHLGKSNNFQKPKPAKGKPEAHFSLIHYAGTVDYNIAGWLDKN 600 Query: 601 KDPLNETVVGLYQKSAMKTLAQLFSGAQTAEGEGAGGGAKKGGKKKGSSFQTVSALFREN 660 KDPLNETVVGLYQKSAMKTLA LF GA AE E GG KKGGKKKGSSFQTVSALFREN Sbjct: 601 KDPLNETVVGLYQKSAMKTLALLFVGATGAEAEAGGG--KKGGKKKGSSFQTVSALFREN 658 Query: 661 LNKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRIL 720 LNKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRIL Sbjct: 659 LNKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRIL 718 Query: 721 YADFKQRYKVLNASAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLE 780 YADFKQRYKVLNASAIPEGQFIDSKKASEKLL SIDIDHTQYKFGHTKVFFKAGLLGLLE Sbjct: 719 YADFKQRYKVLNASAIPEGQFIDSKKASEKLLGSIDIDHTQYKFGHTKVFFKAGLLGLLE 778 Query: 781 EMRDDKLAQLITRTQARCRGFLARVEYQRMVERREAIFCIQYNIRSFMNVKHWPWMKLFF 840 EMRD+KLAQLITRTQA CRGFLARVEYQ+MVERRE+IFCIQYN+R+FMNVKHWPWMKL+F Sbjct: 779 EMRDEKLAQLITRTQAMCRGFLARVEYQKMVERRESIFCIQYNVRAFMNVKHWPWMKLYF 838 Query: 841 KIKPLLKSAETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAE 900 KIKPLLKSAETEKEMA MKEEF+K K+ELAK+EAKRKELEEKMVTL++EKNDLQLQVQAE Sbjct: 839 KIKPLLKSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAE 898 Query: 901 AEGLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDI 960 A+ LADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDI Sbjct: 899 ADSLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDI 958 Query: 961 DDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEE 1020 DDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEE Sbjct: 959 DDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEE 1018 Query: 1021 DKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQ 1080 DKVNTLTKAKIKLEQQVDDLEGSLEQEKK+RMDLERAKRKLEGDLKLAQES MDIEN+KQ Sbjct: 1019 DKVNTLTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDLKLAQESTMDIENDKQ 1078 Query: 1081 QLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEK 1140 QLDEKLKKKEFE+S LQSKIEDEQALG+QLQKKIKELQARIEELEEEIEAERASRAKAEK Sbjct: 1079 QLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERASRAKAEK 1138 Query: 1141 QRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRK 1200 QRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRK Sbjct: 1139 QRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRK 1198 Query: 1201 KHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLED 1260 KHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASN+ETVSKAKGNLEKMCR LED Sbjct: 1199 KHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALED 1258 Query: 1261 QLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEE 1320 QLSE+K+KEEEQQRLINDLTAQR RLQTESGE+SRQLDEK+ LVSQLSRGKQAFTQQIEE Sbjct: 1259 QLSEIKTKEEEQQRLINDLTAQRARLQTESGEYSRQLDEKDTLVSQLSRGKQAFTQQIEE 1318 Query: 1321 LKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTK 1380 LKRQLEEEIKAK+ALAHALQSSRHDCDLLREQYEEEQE+KAELQRA+SKAN+EVAQWRTK Sbjct: 1319 LKRQLEEEIKAKSALAHALQSSRHDCDLLREQYEEEQEAKAELQRAMSKANSEVAQWRTK 1378 Query: 1381 YETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVER 1440 YETDAIQRTEELEEAKKKLAQRLQ AEEHVEAVNAKCASLEKTKQRLQNEVEDLM+DVER Sbjct: 1379 YETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVER 1438 Query: 1441 TNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQ 1500 TNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKE+RSL TELFKIKNAYEESLDQ Sbjct: 1439 TNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKESRSLSTELFKIKNAYEESLDQ 1498 Query: 1501 LETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHE 1560 LETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEK ELQAALEEAEASLEHE Sbjct: 1499 LETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKSELQAALEEAEASLEHE 1558 Query: 1561 EGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRL 1620 EGKILRIQLELNQVKSEVDRKIAEKDEEIDQ+KRNHIRIVESMQSTLDAEIRSRNDAIRL Sbjct: 1559 EGKILRIQLELNQVKSEVDRKIAEKDEEIDQMKRNHIRIVESMQSTLDAEIRSRNDAIRL 1618 Query: 1621 KKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMV 1680 KKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQ ILKDTQ+HLDDALRSQEDLKEQLAMV Sbjct: 1619 KKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQAILKDTQLHLDDALRSQEDLKEQLAMV 1678 Query: 1681 ERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDI 1740 ERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDI Sbjct: 1679 ERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDI 1738 Query: 1741 SQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQ 1800 SQ+QGEMEDI+QEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKN+EQTVKDLQ Sbjct: 1739 SQIQGEMEDIIQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQ 1798 Query: 1801 LRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQT 1860 RLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRN EAVKGLRKHER+VKELTYQT Sbjct: 1799 HRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNVEAVKGLRKHERKVKELTYQT 1858 Query: 1861 EEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAE 1920 EEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSN NL+KFR++QHELEEAEERADIAE Sbjct: 1859 EEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNVNLSKFRRIQHELEEAEERADIAE 1918 Query: 1921 SQVNKLRVKSREVHTKVISEE 1941 SQVNKLRVKSREVHTK+ISEE Sbjct: 1919 SQVNKLRVKSREVHTKIISEE 1939 >gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo sapiens] Length = 1937 Score = 3513 bits (9110), Expect = 0.0 Identities = 1796/1939 (92%), Positives = 1879/1939 (96%), Gaps = 5/1939 (0%) Query: 2 SSDSELAVFGEAAPFLRKSERERIEAQNRPFDAKTSVFVAEPKESFVKGTIQSREGGKVT 61 SSD+E+AVFGEAAP+LRKSE+ERIEAQN+PFDAKTSVFVAEPKES+VK TIQS+EGGKVT Sbjct: 4 SSDAEMAVFGEAAPYLRKSEKERIEAQNKPFDAKTSVFVAEPKESYVKSTIQSKEGGKVT 63 Query: 62 VKTEGGATLTVKDDQVFPMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGL 121 VKTEGGATLTV++DQVFPMNPPKYDKIEDMAMMTHLHEP VLYNLKERYAAWMIYTYSGL Sbjct: 64 VKTEGGATLTVREDQVFPMNPPKYDKIEDMAMMTHLHEPGVLYNLKERYAAWMIYTYSGL 123 Query: 122 FCVTVNPYKWLPVYKPEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGES 181 FCVTVNPYKWLPVYKPEVV AYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGES Sbjct: 124 FCVTVNPYKWLPVYKPEVVAAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGES 183 Query: 182 GAGKTVNTKRVIQYFATIAVTGEKKKEEITSGKIQGTLEDQIISANPLLEAFGNAKTVRN 241 GAGKTVNTKRVIQYFATIAVTGEKKK+E SGK+QGTLEDQIISANPLLEAFGNAKTVRN Sbjct: 184 GAGKTVNTKRVIQYFATIAVTGEKKKDE--SGKMQGTLEDQIISANPLLEAFGNAKTVRN 241 Query: 242 DNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVVFQLKAERSYHIFYQITSNKKPELI 301 DNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRV FQLKAERSYHIFYQITSNKKP+LI Sbjct: 242 DNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQITSNKKPDLI 301 Query: 302 EMLLITTNPYDYPFVSQGEISVASIDDQEELMATDSAIDILGFTNEEKVSIYKLTGAVMH 361 EMLLITTNPYDY FVSQGEI+V SIDDQEELMATDSAIDILGFT EEKVSIYKLTGAVMH Sbjct: 302 EMLLITTNPYDYAFVSQGEITVPSIDDQEELMATDSAIDILGFTPEEKVSIYKLTGAVMH 361 Query: 362 YGNLKFKQKQREEQAEPDGTEVADKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTVE 421 YGN+KFKQKQREEQAEPDGTEVADKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTV+ Sbjct: 362 YGNMKFKQKQREEQAEPDGTEVADKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTVQ 421 Query: 422 QVSNAVGALAKAVYEKMFLWMVARINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCI 481 QV NAVGALAKAVYEKMFLWMV RINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCI Sbjct: 422 QVYNAVGALAKAVYEKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCI 481 Query: 482 NFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEEC 541 NFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKP+GIFSILEEEC Sbjct: 482 NFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPLGIFSILEEEC 541 Query: 542 MFPKATDTSFKNKLYDQHLGKSANFQKPKVVKGKAEAHFALIHYAGVVDYNITGWLEKNK 601 MFPKATDTSFKNKLYDQHLGKSANFQKPKVVKGKAEAHF+LIHYAG VDYNITGWL+KNK Sbjct: 542 MFPKATDTSFKNKLYDQHLGKSANFQKPKVVKGKAEAHFSLIHYAGTVDYNITGWLDKNK 601 Query: 602 DPLNETVVGLYQKSAMKTLAQLFSGAQTAEGEGAGGGAKKGGKKKGSSFQTVSALFRENL 661 DPLN+TVVGLYQKSAMKTLA LFS +AE + + AKKG KKKGSSFQTVSALFRENL Sbjct: 602 DPLNDTVVGLYQKSAMKTLASLFSTYASAEADSS---AKKGAKKKGSSFQTVSALFRENL 658 Query: 662 NKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILY 721 NKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILY Sbjct: 659 NKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILY 718 Query: 722 ADFKQRYKVLNASAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEE 781 DFKQRYKVLNASAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEE Sbjct: 719 GDFKQRYKVLNASAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEE 778 Query: 782 MRDDKLAQLITRTQARCRGFLARVEYQRMVERREAIFCIQYNIRSFMNVKHWPWMKLFFK 841 MRD+KLAQ+ITRTQA CRGFL RVEYQ+M++RREA+FCIQYN+R+FMNVKHWPWMKLFFK Sbjct: 779 MRDEKLAQIITRTQAVCRGFLMRVEYQKMLQRREALFCIQYNVRAFMNVKHWPWMKLFFK 838 Query: 842 IKPLLKSAETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEA 901 IKPLLKSAETEKEMATMKEEFQK KDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQ+EA Sbjct: 839 IKPLLKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEA 898 Query: 902 EGLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDID 961 + LADAEERC+QLIK KIQLEAKIKEVTERAE+EEEINAELTAKKRKLEDECSELKKDID Sbjct: 899 DSLADAEERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDID 958 Query: 962 DLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEED 1021 DLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKL+KEKKALQE HQQTLDDLQAEED Sbjct: 959 DLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEED 1018 Query: 1022 KVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQ 1081 KVN LTKAK KLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQES MD+EN+KQQ Sbjct: 1019 KVNILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQ 1078 Query: 1082 LDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQ 1141 LDEKL+KKEFEISNL SKIEDEQA+ IQLQKKIKELQARIEEL EEIEAERASRAKAEKQ Sbjct: 1079 LDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQ 1138 Query: 1142 RSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKK 1201 RSDLSRELEEISERLEEAGGATSAQ+E+NKKREAEFQK+RRDLEEATLQHEA A LRKK Sbjct: 1139 RSDLSRELEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRKK 1198 Query: 1202 HADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQ 1261 HADS+AELGEQIDNLQRVKQKLEKEKSE+KME DDL+SN E +SKAKGNLEKMCR+LEDQ Sbjct: 1199 HADSMAELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGNLEKMCRSLEDQ 1258 Query: 1262 LSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEEL 1321 +SELK+KEEEQQRLINDLTAQR RLQTE+GE+SRQLDEK+ALVSQLSR KQA TQQIEEL Sbjct: 1259 VSELKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEEL 1318 Query: 1322 KRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKY 1381 K QLEEE KAKNALAHALQSSRHDCDLLREQYEEEQE KAELQRALSKAN+EVAQWRTKY Sbjct: 1319 KHQLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKY 1378 Query: 1382 ETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERT 1441 ETDAIQRTEELEEAKKKLAQRLQ AEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVER+ Sbjct: 1379 ETDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERS 1438 Query: 1442 NAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQL 1501 NAACAALDKKQRNFDK+L+EWKQK EET AELEASQKE+RSL TELFK+KN YEESLDQL Sbjct: 1439 NAACAALDKKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELFKVKNVYEESLDQL 1498 Query: 1502 ETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEE 1561 ETL+RENKNLQQEISDLTEQIAEGGK+IHELEKIKKQVEQEKCE+QAALEEAEASLEHEE Sbjct: 1499 ETLRRENKNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEE 1558 Query: 1562 GKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLK 1621 GKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNH R+VE+MQSTLDAEIRSRNDA+R+K Sbjct: 1559 GKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHTRVVETMQSTLDAEIRSRNDALRVK 1618 Query: 1622 KKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVE 1681 KKMEGDLNEMEIQLNHANR+AAE+LRNYRNTQGILK+TQ+HLDDALR QEDLKEQLA+VE Sbjct: 1619 KKMEGDLNEMEIQLNHANRLAAESLRNYRNTQGILKETQLHLDDALRGQEDLKEQLAIVE 1678 Query: 1682 RRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDIS 1741 RRANLLQAEIEEL ATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLE D+S Sbjct: 1679 RRANLLQAEIEELWATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVS 1738 Query: 1742 QMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQL 1801 Q+Q E+E+++QE+RNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKN+EQTVKDLQ Sbjct: 1739 QLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQH 1798 Query: 1802 RLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTE 1861 RLDEAEQLALKGGKKQIQKLEARVRELEGEVE+EQKRNAEAVKGLRKHERRVKELTYQTE Sbjct: 1799 RLDEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHERRVKELTYQTE 1858 Query: 1862 EDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAES 1921 EDRKN+LRLQDLVDKLQAKVKSYKRQAEEAEEQSN NL+KFRKLQHELEEAEERADIAES Sbjct: 1859 EDRKNVLRLQDLVDKLQAKVKSYKRQAEEAEEQSNANLSKFRKLQHELEEAEERADIAES 1918 Query: 1922 QVNKLRVKSREVHTKVISE 1940 QVNKLRVKSREVHTK+ +E Sbjct: 1919 QVNKLRVKSREVHTKISAE 1937 >gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo sapiens] Length = 1939 Score = 3498 bits (9070), Expect = 0.0 Identities = 1783/1941 (91%), Positives = 1870/1941 (96%), Gaps = 2/1941 (0%) Query: 1 MSSDSELAVFGEAAPFLRKSERERIEAQNRPFDAKTSVFVAEPKESFVKGTIQSREGGKV 60 MSSDSE+A+FGEAAPFLRKSE+ERIEAQN+PFDAKTSVFV +PKES+VK +QSREGGKV Sbjct: 1 MSSDSEMAIFGEAAPFLRKSEKERIEAQNKPFDAKTSVFVVDPKESYVKAIVQSREGGKV 60 Query: 61 TVKTEGGATLTVKDDQVFPMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSG 120 T KTE GAT+TVK+DQVF MNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSG Sbjct: 61 TAKTEAGATVTVKEDQVFSMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSG 120 Query: 121 LFCVTVNPYKWLPVYKPEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGE 180 LFCVTVNPYKWLPVY PEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGE Sbjct: 121 LFCVTVNPYKWLPVYNPEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGE 180 Query: 181 SGAGKTVNTKRVIQYFATIAVTGEKKKEEITSGKIQGTLEDQIISANPLLEAFGNAKTVR 240 SGAGKTVNTKRVIQYFATIAVTGEKKKEE SGK+QGTLEDQIISANPLLEAFGNAKTVR Sbjct: 181 SGAGKTVNTKRVIQYFATIAVTGEKKKEEPASGKMQGTLEDQIISANPLLEAFGNAKTVR 240 Query: 241 NDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVVFQLKAERSYHIFYQITSNKKPEL 300 NDNSSRFGKFIRIHFG TGKLASADIETYLLEKSRV FQLKAERSYHIFYQI SNKKPEL Sbjct: 241 NDNSSRFGKFIRIHFGATGKLASADIETYLLEKSRVTFQLKAERSYHIFYQILSNKKPEL 300 Query: 301 IEMLLITTNPYDYPFVSQGEISVASIDDQEELMATDSAIDILGFTNEEKVSIYKLTGAVM 360 IEMLLITTNPYD+ FVSQGEI+V SIDDQEELMATDSA+DILGFT +EKV+IYKLTGAVM Sbjct: 301 IEMLLITTNPYDFAFVSQGEITVPSIDDQEELMATDSAVDILGFTADEKVAIYKLTGAVM 360 Query: 361 HYGNLKFKQKQREEQAEPDGTEVADKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTV 420 HYGN+KFKQKQREEQAEPDGTEVADKAAYL SLNSADLLK+LCYPRVKVGNE+VTKGQTV Sbjct: 361 HYGNMKFKQKQREEQAEPDGTEVADKAAYLTSLNSADLLKSLCYPRVKVGNEFVTKGQTV 420 Query: 421 EQVSNAVGALAKAVYEKMFLWMVARINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLC 480 +QV NAVGALAKA+YEKMFLWMV RINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLC Sbjct: 421 QQVYNAVGALAKAIYEKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLC 480 Query: 481 INFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEE 540 INFTNEKLQQFFNHHMFVLEQEEYKKEGIEW FIDFGMDLAACIELIEKPMGIFSILEEE Sbjct: 481 INFTNEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLAACIELIEKPMGIFSILEEE 540 Query: 541 CMFPKATDTSFKNKLYDQHLGKSANFQKPKVVKGKAEAHFALIHYAGVVDYNITGWLEKN 600 CMFPKATDTSFKNKLY+QHLGKS NFQKPK KGK EAHF+L+HYAG VDYNI GWL+KN Sbjct: 541 CMFPKATDTSFKNKLYEQHLGKSNNFQKPKPAKGKPEAHFSLVHYAGTVDYNIAGWLDKN 600 Query: 601 KDPLNETVVGLYQKSAMKTLAQLFSGAQTAEGEGAGGGAKKGGKKKGSSFQTVSALFREN 660 KDPLNETVVGLYQKSAMKTLA LFSGAQTAE EG GG KKGGKKKGSSFQTVSALFREN Sbjct: 601 KDPLNETVVGLYQKSAMKTLAFLFSGAQTAEAEGGGG--KKGGKKKGSSFQTVSALFREN 658 Query: 661 LNKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRIL 720 LNKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRIL Sbjct: 659 LNKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRIL 718 Query: 721 YADFKQRYKVLNASAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLE 780 YADFKQRYKVLNASAIPEGQFIDSKKASEKLL SI+IDHTQYKFGHTKVFFKAGLLG LE Sbjct: 719 YADFKQRYKVLNASAIPEGQFIDSKKASEKLLGSIEIDHTQYKFGHTKVFFKAGLLGTLE 778 Query: 781 EMRDDKLAQLITRTQARCRGFLARVEYQRMVERREAIFCIQYNIRSFMNVKHWPWMKLFF 840 EMRD+KLAQLITRTQA CRGFL RVE+++M+ERRE+IFCIQYNIR+FMNVKHWPWMKL+F Sbjct: 779 EMRDEKLAQLITRTQAICRGFLMRVEFRKMMERRESIFCIQYNIRAFMNVKHWPWMKLYF 838 Query: 841 KIKPLLKSAETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAE 900 KIKPLLKSAETEKEMA MKEEF+K K+ELAK+EAKRKELEEKMVTL++EKNDLQLQVQAE Sbjct: 839 KIKPLLKSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAE 898 Query: 901 AEGLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDI 960 A+ LADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDI Sbjct: 899 ADALADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDI 958 Query: 961 DDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEE 1020 DDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQ EE Sbjct: 959 DDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQMEE 1018 Query: 1021 DKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQ 1080 DKVNTLTKAK KLEQQVDDLEGSLEQEKKL MDLERAKRKLEGDLKLAQES MD EN+KQ Sbjct: 1019 DKVNTLTKAKTKLEQQVDDLEGSLEQEKKLCMDLERAKRKLEGDLKLAQESTMDTENDKQ 1078 Query: 1081 QLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEK 1140 QL+EKLKKKEFE+SNLQ KIEDEQAL IQLQKKIKELQARIEELEEEIEAERASRAKAEK Sbjct: 1079 QLNEKLKKKEFEMSNLQGKIEDEQALAIQLQKKIKELQARIEELEEEIEAERASRAKAEK 1138 Query: 1141 QRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRK 1200 QRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEE+TLQHEATAA LRK Sbjct: 1139 QRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEESTLQHEATAAALRK 1198 Query: 1201 KHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLED 1260 KHADSVAELGEQID+LQRVKQKLEKEKSE+KMEI+DLASN+ETVSKAK N EKMCRTLED Sbjct: 1199 KHADSVAELGEQIDSLQRVKQKLEKEKSELKMEINDLASNMETVSKAKANFEKMCRTLED 1258 Query: 1261 QLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEE 1320 QLSE+K+KEEEQQRLIN+L+AQ+ RL TESGEFSRQLDEK+A+VSQLSRGKQAFTQQIEE Sbjct: 1259 QLSEIKTKEEEQQRLINELSAQKARLHTESGEFSRQLDEKDAMVSQLSRGKQAFTQQIEE 1318 Query: 1321 LKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTK 1380 LKRQLEEE KAK+ LAHALQS+RHDCDLLREQYEEEQE+KAELQR +SKAN+EVAQWRTK Sbjct: 1319 LKRQLEEETKAKSTLAHALQSARHDCDLLREQYEEEQEAKAELQRGMSKANSEVAQWRTK 1378 Query: 1381 YETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVER 1440 YETDAIQRTEELEEAKKKLAQRLQ AEEHVEAVN+KCASLEKTKQRLQNEVEDLM+DVER Sbjct: 1379 YETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNSKCASLEKTKQRLQNEVEDLMIDVER 1438 Query: 1441 TNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQ 1500 +NAAC ALDKKQRNFDK+LAEWKQK EET AELEASQKE+RSL TELFK+KNAYEESLD Sbjct: 1439 SNAACIALDKKQRNFDKVLAEWKQKYEETQAELEASQKESRSLSTELFKVKNAYEESLDH 1498 Query: 1501 LETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHE 1560 LETLKRENKNLQQEISDLTEQIAEGGK IHELEK+KKQ++ EK ELQ +LEEAEASLEHE Sbjct: 1499 LETLKRENKNLQQEISDLTEQIAEGGKHIHELEKVKKQLDHEKSELQTSLEEAEASLEHE 1558 Query: 1561 EGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRL 1620 EGKILRIQLELNQVKSE+DRKIAEKDEE+DQLKRNH+R+VESMQSTLDAEIRSRNDA+R+ Sbjct: 1559 EGKILRIQLELNQVKSEIDRKIAEKDEELDQLKRNHLRVVESMQSTLDAEIRSRNDALRI 1618 Query: 1621 KKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMV 1680 KKKMEGDLNEMEIQLNHANR AAEALRN RNTQGILKDTQ+HLDDA+R Q+DLKEQLAMV Sbjct: 1619 KKKMEGDLNEMEIQLNHANRQAAEALRNLRNTQGILKDTQLHLDDAIRGQDDLKEQLAMV 1678 Query: 1681 ERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDI 1740 ERRANL+QAE+EELRA+LE+TER RK+AEQELLDASERVQLLHTQNTSLINTKKKLETDI Sbjct: 1679 ERRANLMQAEVEELRASLERTERGRKMAEQELLDASERVQLLHTQNTSLINTKKKLETDI 1738 Query: 1741 SQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQ 1800 SQ+QGEMEDI+QEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQ Sbjct: 1739 SQIQGEMEDIVQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQ 1798 Query: 1801 LRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQT 1860 LRLDEAEQLALKGGKKQIQKLEARVRELE EVESEQK N EAVKGLRKHERRVKELTYQT Sbjct: 1799 LRLDEAEQLALKGGKKQIQKLEARVRELESEVESEQKHNVEAVKGLRKHERRVKELTYQT 1858 Query: 1861 EEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAE 1920 EEDRKNILRLQDLVDKLQ KVK+YKRQAEEAEEQSN NLAKFRKLQHELEEA+ERADIAE Sbjct: 1859 EEDRKNILRLQDLVDKLQTKVKAYKRQAEEAEEQSNVNLAKFRKLQHELEEAKERADIAE 1918 Query: 1921 SQVNKLRVKSREVHTKVISEE 1941 SQVNKLRVKSREVHTKVISEE Sbjct: 1919 SQVNKLRVKSREVHTKVISEE 1939 >gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo sapiens] Length = 1940 Score = 3231 bits (8378), Expect = 0.0 Identities = 1639/1932 (84%), Positives = 1788/1932 (92%), Gaps = 5/1932 (0%) Query: 1 MSSDSELAVFGEAAPFLRKSERERIEAQNRPFDAKTSVFVAEPKESFVKGTIQSREGGKV 60 MSSD+E+ VFG AAPFLRKSE+ERIEAQN+PFDAKT FV + KE + KG I+S + GKV Sbjct: 1 MSSDTEMEVFGIAAPFLRKSEKERIEAQNQPFDAKTYCFVVDSKEEYAKGKIKSSQDGKV 60 Query: 61 TVKTEGGATLTVKDDQVFPMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSG 120 TV+TE TL VK + V+ MNPPK+D+IEDMAM+THL+EPAVLYNLK+RY +WMIYTYSG Sbjct: 61 TVETEDNRTLVVKPEDVYAMNPPKFDRIEDMAMLTHLNEPAVLYNLKDRYTSWMIYTYSG 120 Query: 121 LFCVTVNPYKWLPVYKPEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGE 180 LFCVTVNPYKWLPVY PEVV YRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGE Sbjct: 121 LFCVTVNPYKWLPVYNPEVVEGYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGE 180 Query: 181 SGAGKTVNTKRVIQYFATIAVTGEKKKEEITSGKIQGTLEDQIISANPLLEAFGNAKTVR 240 SGAGKTVNTKRVIQYFATIA TG+ K++ K++GTLEDQIISANPLLEAFGNAKTVR Sbjct: 181 SGAGKTVNTKRVIQYFATIAATGDLAKKK--DSKMKGTLEDQIISANPLLEAFGNAKTVR 238 Query: 241 NDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVVFQLKAERSYHIFYQITSNKKPEL 300 NDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRV FQLKAERSYHIFYQI SNKKPEL Sbjct: 239 NDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQILSNKKPEL 298 Query: 301 IEMLLITTNPYDYPFVSQGEISVASIDDQEELMATDSAIDILGFTNEEKVSIYKLTGAVM 360 IE+LLITTNPYDYPF+SQGEI VASIDD EEL+ATDSAIDILGFT EEK +YKLTGAVM Sbjct: 299 IELLLITTNPYDYPFISQGEILVASIDDAEELLATDSAIDILGFTPEEKSGLYKLTGAVM 358 Query: 361 HYGNLKFKQKQREEQAEPDGTEVADKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTV 420 HYGN+KFKQKQREEQAEPDGTEVADK AYL LNS+DLLKALC+PRVKVGNEYVTKGQTV Sbjct: 359 HYGNMKFKQKQREEQAEPDGTEVADKTAYLMGLNSSDLLKALCFPRVKVGNEYVTKGQTV 418 Query: 421 EQVSNAVGALAKAVYEKMFLWMVARINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLC 480 +QV +AV AL+K+VYEK+FLWMV RINQQLDTK PRQ+FIGVLDIAGFEIF++NSLEQLC Sbjct: 419 DQVHHAVNALSKSVYEKLFLWMVTRINQQLDTKLPRQHFIGVLDIAGFEIFEYNSLEQLC 478 Query: 481 INFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEE 540 INFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEE Sbjct: 479 INFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEE 538 Query: 541 CMFPKATDTSFKNKLYDQHLGKSANFQKPKVVKGKAEAHFALIHYAGVVDYNITGWLEKN 600 CMFPKATDTSFKNKLYDQHLGKS NFQKPKVVKG+AEAHF+LIHYAG VDY+++GWLEKN Sbjct: 539 CMFPKATDTSFKNKLYDQHLGKSNNFQKPKVVKGRAEAHFSLIHYAGTVDYSVSGWLEKN 598 Query: 601 KDPLNETVVGLYQKSAMKTLAQLFSGAQTAEGEGAGGGAKKGGKKKGSSFQTVSALFREN 660 KDPLNETVVGLYQKS+ + LA L++ TA+ A G KK KKKGSSFQTVSALFREN Sbjct: 599 KDPLNETVVGLYQKSSNRLLAHLYATFATAD---ADSGKKKVAKKKGSSFQTVSALFREN 655 Query: 661 LNKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRIL 720 LNKLM+NLR+THPHFVRCIIPNETKTPGAMEH LVLHQLRCNGVLEGIRICRKGFP+RIL Sbjct: 656 LNKLMSNLRTTHPHFVRCIIPNETKTPGAMEHSLVLHQLRCNGVLEGIRICRKGFPNRIL 715 Query: 721 YADFKQRYKVLNASAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLE 780 Y DFKQRY+VLNASAIPEGQFIDSKKA EKLLASIDIDHTQYKFGHTKVFFKAGLLG LE Sbjct: 716 YGDFKQRYRVLNASAIPEGQFIDSKKACEKLLASIDIDHTQYKFGHTKVFFKAGLLGTLE 775 Query: 781 EMRDDKLAQLITRTQARCRGFLARVEYQRMVERREAIFCIQYNIRSFMNVKHWPWMKLFF 840 EMRDD+LA+LITRTQA CRGFL RVE+Q+MV+RRE+IFCIQYNIRSFMNVKHWPWMKLFF Sbjct: 776 EMRDDRLAKLITRTQAVCRGFLMRVEFQKMVQRRESIFCIQYNIRSFMNVKHWPWMKLFF 835 Query: 841 KIKPLLKSAETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAE 900 KIKPLLKSAETEKEMATMKEEFQK KDELAKSEAKRKELEEK+VTL++EKNDLQLQVQAE Sbjct: 836 KIKPLLKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAE 895 Query: 901 AEGLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDI 960 +E L DAEERCDQLIK K QLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDI Sbjct: 896 SENLLDAEERCDQLIKAKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDI 955 Query: 961 DDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEE 1020 DDLELTLAKVEKEKHATENKVKNLTEE++GLDETIAKLT+EKKALQEAHQQ LDDLQAEE Sbjct: 956 DDLELTLAKVEKEKHATENKVKNLTEELSGLDETIAKLTREKKALQEAHQQALDDLQAEE 1015 Query: 1021 DKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQ 1080 DKVN+L K K KLEQQV+DLE SLEQEKKLR+DLER KRKLEGDLKLAQESI+D+EN+KQ Sbjct: 1016 DKVNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQ 1075 Query: 1081 QLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEK 1140 QLDE+LKKK+FE LQSK+EDEQ LG+Q QKKIKELQARIEELEEEIEAERA+RAK EK Sbjct: 1076 QLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEK 1135 Query: 1141 QRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRK 1200 QRSD +RELEE+SERLEEAGG TS QIE+NKKREAEF K+RRDLEEATLQHEA A LRK Sbjct: 1136 QRSDYARELEELSERLEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEAMVAALRK 1195 Query: 1201 KHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLED 1260 KHADSVAELGEQIDNLQRVKQKLEKEKSE K+EIDDL+S++E+VSK+K NLEK+CRTLED Sbjct: 1196 KHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLED 1255 Query: 1261 QLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEE 1320 QLSE + K EE QR +++LT Q+ RLQTE+GE SRQL+EKE++VSQLSR KQAFTQQ EE Sbjct: 1256 QLSEARGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEE 1315 Query: 1321 LKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTK 1380 LKRQLEEE KAKNALAHALQSSRHDCDLLREQYEEEQE KAELQRALSKAN+EVAQWRTK Sbjct: 1316 LKRQLEEENKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTK 1375 Query: 1381 YETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVER 1440 YETDAIQRTEELEEAKKKLAQRLQ +EE VEAVNAKCASLEKTKQRLQ EVEDLM+DVER Sbjct: 1376 YETDAIQRTEELEEAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVER 1435 Query: 1441 TNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQ 1500 N+ AALDKKQRNFDK+LAEWK KCEE+ AELEAS KE+RSL TELFK+KNAYEE+LDQ Sbjct: 1436 ANSLAAALDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQ 1495 Query: 1501 LETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHE 1560 LET+KRENKNL+QEI+DLTEQIAE GK IHELEK +KQ+E EK ++Q ALEEAEA+LEHE Sbjct: 1496 LETVKRENKNLEQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQLALEEAEAALEHE 1555 Query: 1561 EGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRL 1620 E KILRIQLEL QVKSE+DRKIAEKDEEI+QLKRN+ R VE+MQS LDAE+RSRN+AIRL Sbjct: 1556 EAKILRIQLELTQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSALDAEVRSRNEAIRL 1615 Query: 1621 KKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMV 1680 KKKMEGDLNE+EIQL+HANR AAE L++ R+ QG LKDTQ+HLDDALR QEDLKEQLA+V Sbjct: 1616 KKKMEGDLNEIEIQLSHANRQAAETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIV 1675 Query: 1681 ERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDI 1740 ERRANLLQAE+EELRATLEQTER+RK+AEQELLD++ERVQLLHTQNTSLI+TKKKLETD+ Sbjct: 1676 ERRANLLQAEVEELRATLEQTERARKLAEQELLDSNERVQLLHTQNTSLIHTKKKLETDL 1735 Query: 1741 SQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQ 1800 Q+Q E+ED ++ARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKN+EQTVKDLQ Sbjct: 1736 MQLQSEVEDASRDARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQ 1795 Query: 1801 LRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQT 1860 RLDEAEQLALKGGKKQIQKLE R+RELE E+E EQK+N E+VKGLRK+ERRVKELTYQ+ Sbjct: 1796 HRLDEAEQLALKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLRKYERRVKELTYQS 1855 Query: 1861 EEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAE 1920 EEDRKN+LRLQDLVDKLQ KVKSYKRQAEEA+EQ+N +L KFRK QHELEEAEERADIAE Sbjct: 1856 EEDRKNVLRLQDLVDKLQVKVKSYKRQAEEADEQANAHLTKFRKAQHELEEAEERADIAE 1915 Query: 1921 SQVNKLRVKSRE 1932 SQVNKLR K+R+ Sbjct: 1916 SQVNKLRAKTRD 1927 Score = 224 bits (571), Expect = 6e-58 Identities = 241/988 (24%), Positives = 448/988 (45%), Gaps = 150/988 (15%) Query: 996 AKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLE 1055 A+ KE ++E Q+T D+L E K L + + L Q+ +DL+ ++ E Sbjct: 844 AETEKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAES------- 896 Query: 1056 RAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIK 1115 E+++D E ++ D+ +K K QL+ KIK Sbjct: 897 --------------ENLLDAE---ERCDQLIKAK------------------FQLEAKIK 921 Query: 1116 ELQARIEELEEEIEAE-RASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKRE 1174 E+ R E+ EEEI AE A + K E + S+L ++++++ T A++E K++ Sbjct: 922 EVTERAED-EEEINAELTAKKRKLEDECSELKKDIDDLE--------LTLAKVE--KEKH 970 Query: 1175 AEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQK---LEKEKSEMK 1231 A K++ EE + E A R+K A A + +D+LQ + K L K KS+++ Sbjct: 971 ATENKVKNLTEELSGLDETIAKLTREKKALQEAHQ-QALDDLQAEEDKVNSLNKTKSKLE 1029 Query: 1232 MEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESG 1291 +++DL S++E K + +LE+ R LE +LK +E L ND RL+ + Sbjct: 1030 QQVEDLESSLEQEKKLRVDLERNKRKLE---GDLKLAQESILDLENDKQQLDERLKKKDF 1086 Query: 1292 EFSR---QLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDL 1348 E+ + ++++++ L Q + + +IEEL EEEI+A+ A + R D Sbjct: 1087 EYCQLQSKVEDEQTLGLQFQKKIKELQARIEEL----EEEIEAERATRAKTEKQRSD--- 1139 Query: 1349 LREQYEEEQESKAE-LQRALSKANTEVAQWRTKYETDAIQRTEELEEA-----------K 1396 Y E E +E L+ A +T++ + K E + ++ +LEEA + Sbjct: 1140 ----YARELEELSERLEEAGGVTSTQI-ELNKKREAEFLKLRRDLEEATLQHEAMVAALR 1194 Query: 1397 KKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFD 1456 KK A + E ++ + LEK K + E++DL +E + + A L+K R + Sbjct: 1195 KKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLE 1254 Query: 1457 KILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEIS 1516 L+E + K EE L + L TE ++ EE + L R + Q+ Sbjct: 1255 DQLSEARGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTE 1314 Query: 1517 DLTEQIAEGGKRI-----------HELEKIKKQVEQE---KCELQAALEEAEASLEHEEG 1562 +L Q+ E K H+ + +++Q E+E K ELQ AL +A + Sbjct: 1315 ELKRQLEEENKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANS------- 1367 Query: 1563 KILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKK 1622 E+ Q +++ + ++ EE+++ K+ + ++ + ++A + K+ Sbjct: 1368 -------EVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQ 1420 Query: 1623 KMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQE-DLKEQLAMVE 1681 +++G++ ++ + + AN +AA + RN +L + + +++ E LKE ++ Sbjct: 1421 RLQGEVEDLMVDVERANSLAAALDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLST 1480 Query: 1682 RRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDIS 1741 L A EE LE +R K EQE+ D +E++ +N I+ +K I Sbjct: 1481 ELFKLKNA-YEEALDQLETVKRENKNLEQEIADLTEQI----AENGKTIHELEKSRKQIE 1535 Query: 1742 QMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSA-----HLERMKKNMEQTV 1796 + +++ L+EA A E + I + ++K E D +E++K+N ++TV Sbjct: 1536 LEKADIQLALEEAEAALEHEEAKILRIQLELTQVKSEIDRKIAEKDEEIEQLKRNYQRTV 1595 Query: 1797 KDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKEL 1856 + +Q LD AE + + +K+E + E+E ++ ++ AE +K LR + ++K+ Sbjct: 1596 ETMQSALD-AEVRSRNEAIRLKKKMEGDLNEIEIQLSHANRQAAETLKHLRSVQGQLKDT 1654 Query: 1857 ------TYQTEEDRKNILRL-QDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKL-QHE 1908 + +ED K L + + + LQA+V+ + E+ E + RKL + E Sbjct: 1655 QLHLDDALRGQEDLKEQLAIVERRANLLQAEVEELRATLEQTE--------RARKLAEQE 1706 Query: 1909 LEEAEERADIAESQVNKLRVKSREVHTK 1936 L ++ ER + +Q L +HTK Sbjct: 1707 LLDSNERVQLLHTQNTSL------IHTK 1728 Score = 82.0 bits (201), Expect = 5e-15 Identities = 79/341 (23%), Positives = 155/341 (45%), Gaps = 38/341 (11%) Query: 847 KSAETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLAD 906 ++AET K + +++ + + + L + +++L+E++ + + N LQ +V+ E + Sbjct: 1636 QAAETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEVE-ELRATLE 1694 Query: 907 AEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELT 966 ER +L E ++ + ER + N L K+KLE + +L+ +++D Sbjct: 1695 QTERARKLA------EQELLDSNERVQLLHTQNTSLIHTKKKLETDLMQLQSEVEDASRD 1748 Query: 967 LAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTL 1026 E++ + EE+ +T A L + KK L+ QT+ DLQ D+ L Sbjct: 1749 ARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLE----QTVKDLQHRLDEAEQL 1804 Query: 1027 TKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKL 1086 L+G +Q +KL + + +LEG+ K ES+ + ++++ E Sbjct: 1805 A------------LKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLRKYERRVKELT 1852 Query: 1087 KKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLS 1146 + E + N+ +++D L +LQ K+K + + EE +E+ A KA+ Sbjct: 1853 YQSEEDRKNV-LRLQD---LVDKLQVKVKSYKRQAEEADEQANAHLTKFRKAQ------- 1901 Query: 1147 RELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEA 1187 ELEE ER + A +Q+ + + +F R + E+ Sbjct: 1902 HELEEAEERADIA----ESQVNKLRAKTRDFTSSRMVVHES 1938 Score = 42.7 bits (99), Expect = 0.003 Identities = 29/130 (22%), Positives = 61/130 (46%), Gaps = 7/130 (5%) Query: 1815 KKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLV 1874 +K++ ++ ++ + E+ + + E + L + +L Q + + +N+L ++ Sbjct: 847 EKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDAEERC 906 Query: 1875 DKL-------QAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAESQVNKLR 1927 D+L +AK+K +AE+ EE + AK RKL+ E E ++ D E + K+ Sbjct: 907 DQLIKAKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVE 966 Query: 1928 VKSREVHTKV 1937 + KV Sbjct: 967 KEKHATENKV 976 >gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo sapiens] Length = 1938 Score = 3146 bits (8157), Expect = 0.0 Identities = 1583/1940 (81%), Positives = 1766/1940 (91%), Gaps = 2/1940 (0%) Query: 1 MSSDSELAVFGEAAPFLRKSERERIEAQNRPFDAKTSVFVAEPKESFVKGTIQSREGGKV 60 MSSD+E+A+FGEAAP+LRK E+ERIEAQNRPFD+K + FVA+ KE +VKG IQ+RE KV Sbjct: 1 MSSDAEMAIFGEAAPYLRKPEKERIEAQNRPFDSKKACFVADNKEMYVKGMIQTRENDKV 60 Query: 61 TVKTEGGATLTVKDDQVFPMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSG 120 VKT LT+ +DQVFPMNPPK+DKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSG Sbjct: 61 IVKTLDDRMLTLNNDQVFPMNPPKFDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSG 120 Query: 121 LFCVTVNPYKWLPVYKPEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGE 180 LFCVTVNPYKWLPVYKPEVV AYRGKKRQEAPPHIFSISDNAYQFMLTDR+NQSILITGE Sbjct: 121 LFCVTVNPYKWLPVYKPEVVAAYRGKKRQEAPPHIFSISDNAYQFMLTDRDNQSILITGE 180 Query: 181 SGAGKTVNTKRVIQYFATIAVTGEKKKEEITSGKIQGTLEDQIISANPLLEAFGNAKTVR 240 SGAGKTVNTKRVIQYFATIAVTG+KKKE GK+QGTLEDQII ANPLLEAFGNAKTVR Sbjct: 181 SGAGKTVNTKRVIQYFATIAVTGDKKKET-QPGKMQGTLEDQIIQANPLLEAFGNAKTVR 239 Query: 241 NDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVVFQLKAERSYHIFYQITSNKKPEL 300 NDNSSRFGKFIRIHFG TGKLASADIETYLLEKSRV FQL +ERSYHIFYQI SNKKPEL Sbjct: 240 NDNSSRFGKFIRIHFGATGKLASADIETYLLEKSRVTFQLSSERSYHIFYQIMSNKKPEL 299 Query: 301 IEMLLITTNPYDYPFVSQGEISVASIDDQEELMATDSAIDILGFTNEEKVSIYKLTGAVM 360 I++LLI+TNP+D+PFVSQGE++VASIDD EEL+ATD+AIDILGF++EEKV IYKLTGAVM Sbjct: 300 IDLLLISTNPFDFPFVSQGEVTVASIDDSEELLATDNAIDILGFSSEEKVGIYKLTGAVM 359 Query: 361 HYGNLKFKQKQREEQAEPDGTEVADKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTV 420 HYGN+KFKQKQREEQAEPDGTEVADKA YL LNSA++LK LC PRVKVGNEYVTKGQ V Sbjct: 360 HYGNMKFKQKQREEQAEPDGTEVADKAGYLMGLNSAEMLKGLCCPRVKVGNEYVTKGQNV 419 Query: 421 EQVSNAVGALAKAVYEKMFLWMVARINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLC 480 +QV+N+VGALAKAVYEKMFLWMV RINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLC Sbjct: 420 QQVTNSVGALAKAVYEKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLC 479 Query: 481 INFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEE 540 INFTNEKLQQFFNHHMFVLEQEEYKKEGIEW FIDFGMDLAACIELIEKPMGIFSILEEE Sbjct: 480 INFTNEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLAACIELIEKPMGIFSILEEE 539 Query: 541 CMFPKATDTSFKNKLYDQHLGKSANFQKPKVVKGKAEAHFALIHYAGVVDYNITGWLEKN 600 CMFPKATDTSFKNKLYDQHLGKS NFQKPK KGKAEAHF+L+HYAG VDYNI GWL+KN Sbjct: 540 CMFPKATDTSFKNKLYDQHLGKSNNFQKPKPAKGKAEAHFSLVHYAGTVDYNIAGWLDKN 599 Query: 601 KDPLNETVVGLYQKSAMKTLAQLFSGAQTAEGEGAGGGAKKGGKKKGSSFQTVSALFREN 660 KDPLNETVVGLYQKS++K L+ LFS AE G GG+KKGGKKKGSSFQTVSA+FREN Sbjct: 600 KDPLNETVVGLYQKSSLKLLSFLFSNYAGAE-TGDSGGSKKGGKKKGSSFQTVSAVFREN 658 Query: 661 LNKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRIL 720 LNKLMTNLRSTHPHFVRC+IPNETKTPG M+H LV+HQLRCNGVLEGIRICRKGFPSRIL Sbjct: 659 LNKLMTNLRSTHPHFVRCLIPNETKTPGVMDHYLVMHQLRCNGVLEGIRICRKGFPSRIL 718 Query: 721 YADFKQRYKVLNASAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLE 780 YADFKQRY++LNASAIPEGQFIDSK ASEKLL SID+D Q++FG+TKVFFKAGLLGLLE Sbjct: 719 YADFKQRYRILNASAIPEGQFIDSKNASEKLLNSIDVDREQFRFGNTKVFFKAGLLGLLE 778 Query: 781 EMRDDKLAQLITRTQARCRGFLARVEYQRMVERREAIFCIQYNIRSFMNVKHWPWMKLFF 840 EMRD+KL L+T TQA CRG+L RVE+++M+ERR++IFCIQYNIRSFMNVKHWPWM LFF Sbjct: 779 EMRDEKLVTLMTSTQAVCRGYLMRVEFKKMMERRDSIFCIQYNIRSFMNVKHWPWMNLFF 838 Query: 841 KIKPLLKSAETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAE 900 KIKPLLKSAE EKEMATMKE+F++ K+ELA+SEA+RKELEEKMV+LL+EKNDLQLQVQ+E Sbjct: 839 KIKPLLKSAEAEKEMATMKEDFERTKEELARSEARRKELEEKMVSLLQEKNDLQLQVQSE 898 Query: 901 AEGLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDI 960 E L DAEERC+ LIK+KI LEAK+KE+TER E+EEE+N+EL AKKR LED+CS LK+DI Sbjct: 899 TENLMDAEERCEGLIKSKILLEAKVKELTERLEEEEEMNSELVAKKRNLEDKCSSLKRDI 958 Query: 961 DDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEE 1020 DDLELTL KVEKEKHATENKVKNL+EEM L+E I+KLTKEKK+LQEAHQQTLDDLQ EE Sbjct: 959 DDLELTLTKVEKEKHATENKVKNLSEEMTALEENISKLTKEKKSLQEAHQQTLDDLQVEE 1018 Query: 1021 DKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQ 1080 DKVN L K KLEQQ DDLEGSLEQEKKLR DLERAKRKLEGDLK++QESIMD+EN+KQ Sbjct: 1019 DKVNGLIKINAKLEQQTDDLEGSLEQEKKLRADLERAKRKLEGDLKMSQESIMDLENDKQ 1078 Query: 1081 QLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEK 1140 Q++EKLKKKEFE+S LQ+KI+DEQ +Q QKKIKELQARIEELEEEIEAE RAK EK Sbjct: 1079 QIEEKLKKKEFELSQLQAKIDDEQVHSLQFQKKIKELQARIEELEEEIEAEHTLRAKIEK 1138 Query: 1141 QRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRK 1200 QRSDL+RELEEISERLEEA GATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRK Sbjct: 1139 QRSDLARELEEISERLEEASGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRK 1198 Query: 1201 KHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLED 1260 K ADSVAELGEQIDNLQRVKQKLEKEKSE+KMEIDD+ASN+E +SK+K N+E+ CRT+ED Sbjct: 1199 KQADSVAELGEQIDNLQRVKQKLEKEKSELKMEIDDMASNIEALSKSKSNIERTCRTVED 1258 Query: 1261 QLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEE 1320 Q SE+K+K+E+Q +LI+DL Q+ RLQT++GE S +++EKE+L+SQL++ KQA TQQ+EE Sbjct: 1259 QFSEIKAKDEQQTQLIHDLNMQKARLQTQNGELSHRVEEKESLISQLTKSKQALTQQLEE 1318 Query: 1321 LKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTK 1380 LKRQ+EEE KAKNA+AHALQSSRHDCDLLREQYEEEQE+KAELQRALSKAN+EVAQWRTK Sbjct: 1319 LKRQMEEETKAKNAMAHALQSSRHDCDLLREQYEEEQEAKAELQRALSKANSEVAQWRTK 1378 Query: 1381 YETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVER 1440 YETDAIQRTEELEEAKKKLAQRLQ AEE+ E N+KCASLEKTKQRLQ EVEDLM D+ER Sbjct: 1379 YETDAIQRTEELEEAKKKLAQRLQEAEENTETANSKCASLEKTKQRLQGEVEDLMRDLER 1438 Query: 1441 TNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQ 1500 ++ ACA LDKKQRNFDK+LAEWKQK +E+ AELEA+QKE+RSL TELFK++NAYEE +DQ Sbjct: 1439 SHTACATLDKKQRNFDKVLAEWKQKLDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQ 1498 Query: 1501 LETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHE 1560 LETL+RENKNLQ+EISDLTEQIAE GK + E EK KK VEQEK +LQ ALEE E SLEHE Sbjct: 1499 LETLRRENKNLQEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLEHE 1558 Query: 1561 EGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRL 1620 E KILR+QLEL+QVKSE+DRK+ EKDEEI+QLKRN R E++QS LDAEIRSRNDA+RL Sbjct: 1559 ESKILRVQLELSQVKSELDRKVIEKDEEIEQLKRNSQRAAEALQSVLDAEIRSRNDALRL 1618 Query: 1621 KKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMV 1680 KKKMEGDLNEMEIQL H+NR AE ++ R QG LKD+Q+HLDDALRS EDLKEQLA+V Sbjct: 1619 KKKMEGDLNEMEIQLGHSNRQMAETQKHLRTVQGQLKDSQLHLDDALRSNEDLKEQLAIV 1678 Query: 1681 ERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDI 1740 ERR LL E+EE++ LEQTER+R+++EQELLDAS+RVQLLH+QNTSLINTKKKLE DI Sbjct: 1679 ERRNGLLLEELEEMKVALEQTERTRRLSEQELLDASDRVQLLHSQNTSLINTKKKLEADI 1738 Query: 1741 SQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQ 1800 +Q Q E+E+ +QE+RNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKN+EQTVKDLQ Sbjct: 1739 AQCQAEVENSIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQ 1798 Query: 1801 LRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQT 1860 RLDEAEQLALKGGKKQIQKLE RVRELE E++ EQKR AEA+KG K+ER+VKE+TYQ Sbjct: 1799 HRLDEAEQLALKGGKKQIQKLENRVRELENELDVEQKRGAEALKGAHKYERKVKEMTYQA 1858 Query: 1861 EEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAE 1920 EED KNILRLQDLVDKLQAKVKSYKRQAEEAEEQ+NT L++ R++QHELEEA ERADIAE Sbjct: 1859 EEDHKNILRLQDLVDKLQAKVKSYKRQAEEAEEQANTQLSRCRRVQHELEEAAERADIAE 1918 Query: 1921 SQVNKLRVKSREVHTKVISE 1940 SQVNKLR KSR+V ++ + E Sbjct: 1919 SQVNKLRAKSRDVGSQKMEE 1938 >gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo sapiens] Length = 1935 Score = 3137 bits (8133), Expect = 0.0 Identities = 1571/1938 (81%), Positives = 1769/1938 (91%), Gaps = 5/1938 (0%) Query: 4 DSELAVFGEAAPFLRKSERERIEAQNRPFDAKTSVFVAEPKESFVKGTIQSREGGKVTVK 63 DSE+AVFG AAP+LRKSE+ER+EAQ RPFD K VFV + K+ FVK I SREGGKVT + Sbjct: 3 DSEMAVFGAAAPYLRKSEKERLEAQTRPFDLKKDVFVPDDKQEFVKAKIVSREGGKVTAE 62 Query: 64 TEGGATLTVKDDQVFPMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFC 123 TE G T+TVK+DQV NPPK+DKIEDMAM+T LHEPAVLYNLK+RY +WMIYTYSGLFC Sbjct: 63 TEYGKTVTVKEDQVMQQNPPKFDKIEDMAMLTFLHEPAVLYNLKDRYGSWMIYTYSGLFC 122 Query: 124 VTVNPYKWLPVYKPEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGA 183 VTVNPYKWLPVY PEVV AYRGKKR EAPPHIFSISDNAYQ+MLTDRENQSILITGESGA Sbjct: 123 VTVNPYKWLPVYTPEVVAAYRGKKRSEAPPHIFSISDNAYQYMLTDRENQSILITGESGA 182 Query: 184 GKTVNTKRVIQYFATIAVTGEKKKEEITSGKIQGTLEDQIISANPLLEAFGNAKTVRNDN 243 GKTVNTKRVIQYFA IA G++ K++ + GK GTLEDQII ANP LEAFGNAKTVRNDN Sbjct: 183 GKTVNTKRVIQYFAVIAAIGDRSKKDQSPGK--GTLEDQIIQANPALEAFGNAKTVRNDN 240 Query: 244 SSRFGKFIRIHFGTTGKLASADIETYLLEKSRVVFQLKAERSYHIFYQITSNKKPELIEM 303 SSRFGKFIRIHFG TGKLASADIETYLLEKSRV+FQLKAER YHIFYQI SNKKPEL++M Sbjct: 241 SSRFGKFIRIHFGATGKLASADIETYLLEKSRVIFQLKAERDYHIFYQILSNKKPELLDM 300 Query: 304 LLITTNPYDYPFVSQGEISVASIDDQEELMATDSAIDILGFTNEEKVSIYKLTGAVMHYG 363 LLIT NPYDY F+SQGE +VASIDD EELMATD+A D+LGFT+EEK S+YKLTGA+MH+G Sbjct: 301 LLITNNPYDYAFISQGETTVASIDDAEELMATDNAFDVLGFTSEEKNSMYKLTGAIMHFG 360 Query: 364 NLKFKQKQREEQAEPDGTEVADKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTVEQV 423 N+KFK KQREEQAEPDGTE ADK+AYL LNSADLLK LC+PRVKVGNEYVTKGQ V+QV Sbjct: 361 NMKFKLKQREEQAEPDGTEEADKSAYLMGLNSADLLKGLCHPRVKVGNEYVTKGQNVQQV 420 Query: 424 SNAVGALAKAVYEKMFLWMVARINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINF 483 A GALAKAVYE+MF WMV RIN L+TKQPRQYFIGVLDIAGFEIFDFNS EQLCINF Sbjct: 421 IYATGALAKAVYERMFNWMVTRINATLETKQPRQYFIGVLDIAGFEIFDFNSFEQLCINF 480 Query: 484 TNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEECMF 543 TNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDL ACI+LIEKPMGI SILEEECMF Sbjct: 481 TNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLQACIDLIEKPMGIMSILEEECMF 540 Query: 544 PKATDTSFKNKLYDQHLGKSANFQKPKVVKGKAEAHFALIHYAGVVDYNITGWLEKNKDP 603 PKATD +FK KL+D HLGKSANFQKP+ +KGK EAHF+LIHYAG+VDYNI GWL+KNKDP Sbjct: 541 PKATDMTFKAKLFDNHLGKSANFQKPRNIKGKPEAHFSLIHYAGIVDYNIIGWLQKNKDP 600 Query: 604 LNETVVGLYQKSAMKTLAQLFSGAQTAEGEGAGGGAKKGGKKKGSSFQTVSALFRENLNK 663 LNETVVGLYQKS++K L+ LF+ A+ G KG KKGSSFQTVSAL RENLNK Sbjct: 601 LNETVVGLYQKSSLKLLSTLFANYAGADAPIEKG---KGKAKKGSSFQTVSALHRENLNK 657 Query: 664 LMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYAD 723 LMTNLRSTHPHFVRCIIPNETK+PG M++ LV+HQLRCNGVLEGIRICRKGFP+RILY D Sbjct: 658 LMTNLRSTHPHFVRCIIPNETKSPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGD 717 Query: 724 FKQRYKVLNASAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMR 783 F+QRY++LN +AIPEGQFIDS+K +EKLL+S+DIDH QYKFGHTKVFFKAGLLGLLEEMR Sbjct: 718 FRQRYRILNPAAIPEGQFIDSRKGAEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMR 777 Query: 784 DDKLAQLITRTQARCRGFLARVEYQRMVERREAIFCIQYNIRSFMNVKHWPWMKLFFKIK 843 D++L+++ITR QA+ RG LAR+EY++++ERR+++ IQ+NIR+FM VK+WPWMKL+FKIK Sbjct: 778 DERLSRIITRIQAQSRGVLARMEYKKLLERRDSLLVIQWNIRAFMGVKNWPWMKLYFKIK 837 Query: 844 PLLKSAETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEG 903 PLLKSAE EKEMA+MKEEF ++K+ L KSEA+RKELEEKMV+LL+EKNDLQLQVQAE + Sbjct: 838 PLLKSAEREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDN 897 Query: 904 LADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDL 963 LADAEERCDQLIK KIQLEAK+KE+ ER EDEEE+NAELTAKKRKLEDECSELK+DIDDL Sbjct: 898 LADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDL 957 Query: 964 ELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKV 1023 ELTLAKVEKEKHATENKVKNLTEEMAGLDE IAKLTKEKKALQEAHQQ LDDLQAEEDKV Sbjct: 958 ELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKV 1017 Query: 1024 NTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLD 1083 NTLTKAK+KLEQQVDDLEGSLEQEKK+RMDLERAKRKLEGDLKL QESIMD+EN+KQQLD Sbjct: 1018 NTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLD 1077 Query: 1084 EKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRS 1143 E+LKKK+FE++ L ++IEDEQALG QLQKK+KELQARIEELEEE+EAER +RAK EK RS Sbjct: 1078 ERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRS 1137 Query: 1144 DLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHA 1203 DLSRELEEISERLEEAGGATS QIEMNKKREAEFQKMRRDLEEATLQHEATAA LRKKHA Sbjct: 1138 DLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHA 1197 Query: 1204 DSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLS 1263 DSVAELGEQIDNLQRVKQKLEKEKSE K+E+DD+ SN+E + KAK NLEKMCRTLEDQ++ Sbjct: 1198 DSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMN 1257 Query: 1264 ELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKR 1323 E +SK EE QR +NDLT+QR +LQTE+GE SRQLDEKEAL+SQL+RGK +TQQ+E+LKR Sbjct: 1258 EHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKR 1317 Query: 1324 QLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYET 1383 QLEEE+KAKNALAHALQS+RHDCDLLREQYEEE E+KAELQR LSKAN+EVAQWRTKYET Sbjct: 1318 QLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYET 1377 Query: 1384 DAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNA 1443 DAIQRTEELEEAKKKLAQRLQ AEE VEAVNAKC+SLEKTK RLQNE+EDLM+DVER+NA Sbjct: 1378 DAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNA 1437 Query: 1444 ACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLET 1503 A AALDKKQRNFDKILAEWKQK EE+ +ELE+SQKEARSL TELFK+KNAYEESL+ LET Sbjct: 1438 AAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLET 1497 Query: 1504 LKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGK 1563 KRENKNLQ+EISDLTEQ+ GK IHELEK++KQ+E EK ELQ+ALEEAEASLEHEEGK Sbjct: 1498 FKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGK 1557 Query: 1564 ILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKK 1623 ILR QLE NQ+K+E++RK+AEKDEE++Q KRNH+R+V+S+Q++LDAE RSRN+A+R+KKK Sbjct: 1558 ILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKK 1617 Query: 1624 MEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERR 1683 MEGDLNEMEIQL+HANRMAAEA + ++ Q +LKDTQI LDDA+R+ +DLKE +A+VERR Sbjct: 1618 MEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERR 1677 Query: 1684 ANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQM 1743 NLLQAE+EELRA +EQTERSRK+AEQEL++ SERVQLLH+QNTSLIN KKK++ D+SQ+ Sbjct: 1678 NNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQL 1737 Query: 1744 QGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRL 1803 Q E+E+ +QE RNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQT+KDLQ RL Sbjct: 1738 QTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRL 1797 Query: 1804 DEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEED 1863 DEAEQ+ALKGGKKQ+QKLEARVRELE E+E+EQKRNAE+VKG+RK ERR+KELTYQTEED Sbjct: 1798 DEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEED 1857 Query: 1864 RKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAESQV 1923 RKN+LRLQDLVDKLQ KVK+YKRQAEEAEEQ+NTNL+KFRK+QHEL+EAEERADIAESQV Sbjct: 1858 RKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQV 1917 Query: 1924 NKLRVKSREVHTKVISEE 1941 NKLR KSR++ TK ++EE Sbjct: 1918 NKLRAKSRDIGTKGLNEE 1935 >gi|156104908 myosin heavy chain 6 [Homo sapiens] Length = 1939 Score = 3108 bits (8058), Expect = 0.0 Identities = 1558/1934 (80%), Positives = 1754/1934 (90%), Gaps = 3/1934 (0%) Query: 3 SDSELAVFGEAAPFLRKSERERIEAQNRPFDAKTSVFVAEPKESFVKGTIQSREGGKVTV 62 +D+++A FG AA +LRKSE+ER+EAQ RPFD +T FV + KE FVK I SREGGKV Sbjct: 2 TDAQMADFGAAAQYLRKSEKERLEAQTRPFDIRTECFVPDDKEEFVKAKILSREGGKVIA 61 Query: 63 KTEGGATLTVKDDQVFPMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLF 122 +TE G T+TVK+DQV NPPK+DKIEDMAM+T LHEPAVL+NLKERYAAWMIYTYSGLF Sbjct: 62 ETENGKTVTVKEDQVLQQNPPKFDKIEDMAMLTFLHEPAVLFNLKERYAAWMIYTYSGLF 121 Query: 123 CVTVNPYKWLPVYKPEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESG 182 CVTVNPYKWLPVY EVV AYRGKKR EAPPHIFSISDNAYQ+MLTDRENQSILITGESG Sbjct: 122 CVTVNPYKWLPVYNAEVVAAYRGKKRSEAPPHIFSISDNAYQYMLTDRENQSILITGESG 181 Query: 183 AGKTVNTKRVIQYFATIAVTGEKKKEEITSGKIQGTLEDQIISANPLLEAFGNAKTVRND 242 AGKTVNTKRVIQYFA+IA G++ K++ + +GTLEDQII ANP LEAFGNAKTVRND Sbjct: 182 AGKTVNTKRVIQYFASIAAIGDRGKKDNANAN-KGTLEDQIIQANPALEAFGNAKTVRND 240 Query: 243 NSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVVFQLKAERSYHIFYQITSNKKPELIE 302 NSSRFGKFIRIHFG TGKLASADIETYLLEKSRV+FQLKAER+YHIFYQI SNKKPEL++ Sbjct: 241 NSSRFGKFIRIHFGATGKLASADIETYLLEKSRVIFQLKAERNYHIFYQILSNKKPELLD 300 Query: 303 MLLITTNPYDYPFVSQGEISVASIDDQEELMATDSAIDILGFTNEEKVSIYKLTGAVMHY 362 MLL+T NPYDY FVSQGE+SVASIDD EELMATDSA D+LGFT+EEK +YKLTGA+MHY Sbjct: 301 MLLVTNNPYDYAFVSQGEVSVASIDDSEELMATDSAFDVLGFTSEEKAGVYKLTGAIMHY 360 Query: 363 GNLKFKQKQREEQAEPDGTEVADKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTVEQ 422 GN+KFKQKQREEQAEPDGTE ADK+AYL LNSADLLK LC+PRVKVGNEYVTKGQ+V+Q Sbjct: 361 GNMKFKQKQREEQAEPDGTEDADKSAYLMGLNSADLLKGLCHPRVKVGNEYVTKGQSVQQ 420 Query: 423 VSNAVGALAKAVYEKMFLWMVARINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCIN 482 V ++GALAKAVYEKMF WMV RIN L+TKQPRQYFIGVLDIAGFEIFDFNS EQLCIN Sbjct: 421 VYYSIGALAKAVYEKMFNWMVTRINATLETKQPRQYFIGVLDIAGFEIFDFNSFEQLCIN 480 Query: 483 FTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEECM 542 FTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDL ACI+LIEKPMGI SILEEECM Sbjct: 481 FTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLQACIDLIEKPMGIMSILEEECM 540 Query: 543 FPKATDTSFKNKLYDQHLGKSANFQKPKVVKGKAEAHFALIHYAGVVDYNITGWLEKNKD 602 FPKATD +FK KLYD HLGKS NFQKP+ +KGK EAHF+LIHYAG VDYNI GWLEKNKD Sbjct: 541 FPKATDMTFKAKLYDNHLGKSNNFQKPRNIKGKQEAHFSLIHYAGTVDYNILGWLEKNKD 600 Query: 603 PLNETVVGLYQKSAMKTLAQLFSGAQTAEGEGAGGGAKKGGKKKGSSFQTVSALFRENLN 662 PLNETVV LYQKS++K +A LFS TA+ G KGGKKKGSSFQTVSAL RENLN Sbjct: 601 PLNETVVALYQKSSLKLMATLFSSYATADT--GDSGKSKGGKKKGSSFQTVSALHRENLN 658 Query: 663 KLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYA 722 KLMTNLR+THPHFVRCIIPNE K PG M++ LV+HQLRCNGVLEGIRICRKGFP+RILY Sbjct: 659 KLMTNLRTTHPHFVRCIIPNERKAPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYG 718 Query: 723 DFKQRYKVLNASAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEM 782 DF+QRY++LN AIPEGQFIDS+K +EKLL+S+DIDH QYKFGHTKVFFKAGLLGLLEEM Sbjct: 719 DFRQRYRILNPVAIPEGQFIDSRKGTEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEM 778 Query: 783 RDDKLAQLITRTQARCRGFLARVEYQRMVERREAIFCIQYNIRSFMNVKHWPWMKLFFKI 842 RD++L+++ITR QA+ RG L R+E++++VERR+A+ IQ+NIR+FM VK+WPWMKL+FKI Sbjct: 779 RDERLSRIITRMQAQARGQLMRIEFKKIVERRDALLVIQWNIRAFMGVKNWPWMKLYFKI 838 Query: 843 KPLLKSAETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAE 902 KPLLKSAETEKEMATMKEEF +IK+ L KSEA+RKELEEKMV+LL+EKNDLQLQVQAE + Sbjct: 839 KPLLKSAETEKEMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQD 898 Query: 903 GLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDD 962 L DAEERCDQLIK KIQLEAK+KE+ ER EDEEE+NAELTAKKRKLEDECSELKKDIDD Sbjct: 899 NLNDAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDIDD 958 Query: 963 LELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDK 1022 LELTLAKVEKEKHATENKVKNLTEEMAGLDE IAKLTKEKKALQEAHQQ LDDLQ EEDK Sbjct: 959 LELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQVEEDK 1018 Query: 1023 VNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQL 1082 VN+L+K+K+KLEQQVDDLEGSLEQEKK+RMDLERAKRKLEGDLKL QESIMD+EN+K QL Sbjct: 1019 VNSLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQL 1078 Query: 1083 DEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQR 1142 +EKLKKKEF+I+ SKIEDEQ L +QLQKK+KE QARIEELEEE+EAER +RAK EK R Sbjct: 1079 EEKLKKKEFDINQQNSKIEDEQVLALQLQKKLKENQARIEELEEELEAERTARAKVEKLR 1138 Query: 1143 SDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKH 1202 SDLSRELEEISERLEEAGGATS QIEMNKKREAEFQKMRRDLEEATLQHEATAA LRKKH Sbjct: 1139 SDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKH 1198 Query: 1203 ADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQL 1262 ADSVAELGEQIDNLQRVKQKLEKEKSE K+E+DD+ SN+E + KAK NLEK+ RTLEDQ Sbjct: 1199 ADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQA 1258 Query: 1263 SELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELK 1322 +E + K EE QR +ND T QR +LQTE+GE +RQL+EKEAL+SQL+RGK ++TQQ+E+LK Sbjct: 1259 NEYRVKLEEAQRSLNDFTTQRAKLQTENGELARQLEEKEALISQLTRGKLSYTQQMEDLK 1318 Query: 1323 RQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYE 1382 RQLEEE KAKNALAHALQS+RHDCDLLREQYEEE E+KAELQR LSKAN+EVAQWRTKYE Sbjct: 1319 RQLEEEGKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYE 1378 Query: 1383 TDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTN 1442 TDAIQRTEELEEAKKKLAQRLQ AEE VEAVNAKC+SLEKTK RLQNE+EDLM+DVER+N Sbjct: 1379 TDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSN 1438 Query: 1443 AACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLE 1502 AA AALDKKQRNFDKILAEWKQK EE+ +ELE+SQKEARSL TELFK+KNAYEESL+ LE Sbjct: 1439 AAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLE 1498 Query: 1503 TLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEG 1562 T KRENKNLQ+EISDLTEQ+ EGGK +HELEK++KQ+E EK ELQ+ALEEAEASLEHEEG Sbjct: 1499 TFKRENKNLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQSALEEAEASLEHEEG 1558 Query: 1563 KILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKK 1622 KILR QLE NQ+K+E++RK+AEKDEE++Q KRNH R+V+S+Q++LDAE RSRN+ +R+KK Sbjct: 1559 KILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKK 1618 Query: 1623 KMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVER 1682 KMEGDLNEMEIQL+HANRMAAEA + ++ Q +LKDTQI LDDA+R+ +DLKE +A+VER Sbjct: 1619 KMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVER 1678 Query: 1683 RANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQ 1742 R NLLQAE+EELRA +EQTERSRK+AEQEL++ SERVQLLH+QNTSLIN KKK+E+D++Q Sbjct: 1679 RNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMESDLTQ 1738 Query: 1743 MQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLR 1802 +Q E+E+ +QE RNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQT+KDLQ R Sbjct: 1739 LQSEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHR 1798 Query: 1803 LDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEE 1862 LDEAEQ+ALKGGKKQ+QKLEARVRELEGE+E+EQKRNAE+VKG+RK ERR+KELTYQTEE Sbjct: 1799 LDEAEQIALKGGKKQLQKLEARVRELEGELEAEQKRNAESVKGMRKSERRIKELTYQTEE 1858 Query: 1863 DRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAESQ 1922 D+KN+LRLQDLVDKLQ KVK+YKRQAEEAEEQ+NTNL+KFRK+QHEL+EAEERADIAESQ Sbjct: 1859 DKKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQ 1918 Query: 1923 VNKLRVKSREVHTK 1936 VNKLR KSR++ K Sbjct: 1919 VNKLRAKSRDIGAK 1932 Score = 187 bits (475), Expect = 9e-47 Identities = 197/868 (22%), Positives = 377/868 (43%), Gaps = 121/868 (13%) Query: 1088 KKEFEISNLQSKIEDEQALGIQLQK--KIKELQARIEELEEEIEAERASRAKAEKQRSDL 1145 K F+I L E E+ + ++ +IKE + E +E+E + S + +++DL Sbjct: 833 KLYFKIKPLLKSAETEKEMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQ---EKNDL 889 Query: 1146 SRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADS 1205 +++ + L +A I+ + EA+ ++M LE+ E A L K Sbjct: 890 QLQVQAEQDNLNDAEERCDQLIKNKIQLEAKVKEMNERLED----EEEMNAELTAK---- 941 Query: 1206 VAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSEL 1265 K+KLE E SE+K +IDDL + V K K E + L ++++ L Sbjct: 942 --------------KRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGL 987 Query: 1266 KSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQL 1325 +I LT ++ LQ + L +E V+ LS+ K QQ+++L+ L Sbjct: 988 -------DEIIAKLTKEKKALQEAHQQALDDLQVEEDKVNSLSKSKVKLEQQVDDLEGSL 1040 Query: 1326 EEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDA 1385 E+E K + L A + D L +E + + K +L+ L K ++ Q +K E + Sbjct: 1041 EQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQ 1100 Query: 1386 IQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAAC 1445 + + L++ K+ R++ EE +EA A +EK + L E+E++ +E A Sbjct: 1101 VLALQ-LQKKLKENQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGAT 1159 Query: 1446 AAL----DKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQL 1501 + K++ F K+ + ++ + A A +K+ EL E +D L Sbjct: 1160 SVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAEL-------GEQIDNL 1212 Query: 1502 ETLK----RENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASL 1557 + +K +E + E+ D+T + + K LEK+ + +E + E + LEEA+ SL Sbjct: 1213 QRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRSL 1272 Query: 1558 EHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDA 1617 + ++Q E E+ R++ EK+ I QL R + + M+ Sbjct: 1273 NDFTTQRAKLQTE----NGELARQLEEKEALISQLTRGKLSYTQQMED------------ 1316 Query: 1618 IRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQL 1677 LK+++E + A A AL++ R+ +L++ + + K +L Sbjct: 1317 --LKRQLEEE--------GKAKNALAHALQSARHDCDLLREQY-------EEETEAKAEL 1359 Query: 1678 AMVERRANLLQA------EIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLIN 1731 V +AN A E + ++ T E E +K+A Q L DA E V+ ++ + +SL Sbjct: 1360 QRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLA-QRLQDAEEAVEAVNAKCSSLEK 1418 Query: 1732 TKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKN 1791 TK +L Q E+ED++ + + A A L++ ++N Sbjct: 1419 TKHRL-------QNEIEDLMVDVERSNAAA---------------------AALDKKQRN 1450 Query: 1792 MEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKH-E 1850 ++ + + + + +E+ Q L+ +K+ + L + +L+ E E + E K K+ + Sbjct: 1451 FDKILAEWKQKYEES-QSELESSQKEARSLSTELFKLKNAYE-ESLEHLETFKRENKNLQ 1508 Query: 1851 RRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELE 1910 + +LT Q E KN+ L+ + +L+ + + EEAE K + Q E Sbjct: 1509 EEISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFN 1568 Query: 1911 EAEERADIAESQVNKLRVKSREVHTKVI 1938 + + + ++ ++ +++ H +V+ Sbjct: 1569 QIKAEIERKLAEKDEEMEQAKRNHQRVV 1596 Score = 65.1 bits (157), Expect = 6e-10 Identities = 62/313 (19%), Positives = 137/313 (43%), Gaps = 44/313 (14%) Query: 848 SAETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADA 907 +AE +K++ +++ + + +L + +L+E + + + N LQ +++ E + + Sbjct: 1638 AAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELE-ELRAVVEQ 1696 Query: 908 EERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTL 967 ER +L E ++ E +ER + N L +K+K+E + ++L+ ++++ Sbjct: 1697 TERSRKLA------EQELIETSERVQLLHSQNTSLINQKKKMESDLTQLQSEVEEAVQEC 1750 Query: 968 AKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLT 1027 E++ + EE+ +T A L + KK ++ QT+ DLQ D+ + Sbjct: 1751 RNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNME----QTIKDLQHRLDEAEQIA 1806 Query: 1028 -----KAKIKLEQQVDDLEGSL----------------------------EQEKKLRMDL 1054 K KLE +V +LEG L E++KK + L Sbjct: 1807 LKGGKKQLQKLEARVRELEGELEAEQKRNAESVKGMRKSERRIKELTYQTEEDKKNLLRL 1866 Query: 1055 ERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKI 1114 + KL+ +K + + E + K +K + E+ + + + ++ +L+ K Sbjct: 1867 QDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKS 1926 Query: 1115 KELQARIEELEEE 1127 +++ A+ + +EE Sbjct: 1927 RDIGAKQKMHDEE 1939 Score = 33.9 bits (76), Expect = 1.6 Identities = 24/99 (24%), Positives = 46/99 (46%), Gaps = 4/99 (4%) Query: 1843 VKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKF 1902 +K L K KE+ EE R+++ ++K +A+ K + + ++ N + Sbjct: 838 IKPLLKSAETEKEMATMKEE----FGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQV 893 Query: 1903 RKLQHELEEAEERADIAESQVNKLRVKSREVHTKVISEE 1941 + Q L +AEER D +L K +E++ ++ EE Sbjct: 894 QAEQDNLNDAEERCDQLIKNKIQLEAKVKEMNERLEDEE 932 >gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta [Homo sapiens] Length = 1983 Score = 2609 bits (6762), Expect = 0.0 Identities = 1309/1932 (67%), Positives = 1619/1932 (83%), Gaps = 6/1932 (0%) Query: 6 ELAVFGEAAPFLRKSERERIEAQNRPFDAKTSVFVAEPKESFVKGTIQSRE-GGKVTVKT 64 +++ GE+A +LR+ +E + P+D K V+V + ++++V+ ++S GG+VTV+T Sbjct: 45 DVSELGESARYLRQGYQEMTKVHTIPWDGKKRVWVPDEQDAYVEAEVKSEATGGRVTVET 104 Query: 65 EGGATLTVKDDQVFPMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCV 124 + L V++ ++ PMNPP++D +EDMAMMTHL+E +VL+NL++RYA WMIYTYSGLFCV Sbjct: 105 KDQKVLMVREAELQPMNPPRFDLLEDMAMMTHLNEASVLHNLRQRYARWMIYTYSGLFCV 164 Query: 125 TVNPYKWLPVYKPEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAG 184 T+NPYKWLPVY VV AY+GK+R ++PPHI++++DNAY ML +R+NQS+LITGESGAG Sbjct: 165 TINPYKWLPVYTASVVAAYKGKRRSDSPPHIYAVADNAYNDMLRNRDNQSMLITGESGAG 224 Query: 185 KTVNTKRVIQYFATIAVTGEK--KKEEITSGKIQGTLEDQIISANPLLEAFGNAKTVRND 242 KTVNTKRVIQYFA +A G+ KK + + K GTLEDQII ANP +EAFGNAKT+RND Sbjct: 225 KTVNTKRVIQYFAIVAALGDGPGKKAQFLATKTGGTLEDQIIEANPAMEAFGNAKTLRND 284 Query: 243 NSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVVFQLKAERSYHIFYQITSNKKPELIE 302 NSSRFGKFIRIHFG +GKLASADI++YLLEKSRV+FQL ERSYH++YQI S +KPEL + Sbjct: 285 NSSRFGKFIRIHFGPSGKLASADIDSYLLEKSRVIFQLPGERSYHVYYQILSGRKPELQD 344 Query: 303 MLLITTNPYDYPFVSQGEISVASIDDQEELMATDSAIDILGFTNEEKVSIYKLTGAVMHY 362 MLL++ NPYDY F SQG I+V +++D EEL+ATD A+DILGF+ +EK + YK+ GA++H+ Sbjct: 345 MLLLSMNPYDYHFCSQGVITVDNMNDGEELIATDHAMDILGFSVDEKCACYKIVGALLHF 404 Query: 363 GNLKFKQKQREEQAEPDGTEVADKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTVEQ 422 GN+KFKQKQREEQAE DGTE ADKAAYL ++S DLLK L +PRV+VGNEYVTKGQ+VEQ Sbjct: 405 GNMKFKQKQREEQAEADGTESADKAAYLMGVSSGDLLKGLLHPRVRVGNEYVTKGQSVEQ 464 Query: 423 VSNAVGALAKAVYEKMFLWMVARINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCIN 482 V AVGALAKA Y+++F W+V+RINQ LDTK PRQ+FIGVLDIAGFEIF+FNS EQLCIN Sbjct: 465 VVFAVGALAKATYDRLFRWLVSRINQTLDTKLPRQFFIGVLDIAGFEIFEFNSFEQLCIN 524 Query: 483 FTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEECM 542 FTNEKLQQFFN HMFVLEQEEYK+EGI+W FIDFG+DL CI+LIEKP+GI SILEEECM Sbjct: 525 FTNEKLQQFFNQHMFVLEQEEYKREGIDWVFIDFGLDLQPCIDLIEKPLGILSILEEECM 584 Query: 543 FPKATDTSFKNKLYDQHLGKSANFQKPKV-VKGKAEAHFALIHYAGVVDYNITGWLEKNK 601 FPKA+D SF+ KLYD H GKS NFQ+P+ K K +AHF ++HYAGVV Y+I GWLEKNK Sbjct: 585 FPKASDASFRAKLYDNHAGKSPNFQQPRPDKKRKYQAHFEVVHYAGVVPYSIVGWLEKNK 644 Query: 602 DPLNETVVGLYQKSAMKTLAQLFSG-AQTAEGEGAGGGAKKGGKKKGSSFQTVSALFREN 660 DPLNETVV ++QKS + LA L+ A + E G K+ +KK +SFQTVS L +EN Sbjct: 645 DPLNETVVPIFQKSQNRLLATLYENYAGSCSTEPPKSGVKEK-RKKAASFQTVSQLHKEN 703 Query: 661 LNKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRIL 720 LNKLMTNLR+T PHFVRCI+PNE KTPG M+ LVLHQLRCNGVLEGIRICR+GFP+R+L Sbjct: 704 LNKLMTNLRATQPHFVRCIVPNENKTPGVMDAFLVLHQLRCNGVLEGIRICRQGFPNRLL 763 Query: 721 YADFKQRYKVLNASAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLE 780 Y DF+QRY++LN SAIP+ F+DS+KA+EKLL S+D+DHTQY+FGHTKVFFKAGLLG+LE Sbjct: 764 YTDFRQRYRILNPSAIPDDTFMDSRKATEKLLGSLDLDHTQYQFGHTKVFFKAGLLGVLE 823 Query: 781 EMRDDKLAQLITRTQARCRGFLARVEYQRMVERREAIFCIQYNIRSFMNVKHWPWMKLFF 840 E+RD +LA+++T QAR RG L R+EYQR++ R+A+F IQ+NIR+F VK+W WMKLFF Sbjct: 824 ELRDQRLAKVLTLLQARSRGRLMRLEYQRLLGGRDALFTIQWNIRAFNAVKNWSWMKLFF 883 Query: 841 KIKPLLKSAETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAE 900 K+KPLL+SA+ E+E+A ++ E + ++ LA +EAKR+ELEE V++ +EKNDL LQ+QAE Sbjct: 884 KMKPLLRSAQAEEELAALRAELRGLRGALAAAEAKRQELEETHVSITQEKNDLALQLQAE 943 Query: 901 AEGLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDI 960 + LADAEERC LIK+K+QLE K+KE++ER EDEEE+NA+L A++RKLEDEC+ELKKDI Sbjct: 944 QDNLADAEERCHLLIKSKVQLEGKVKELSERLEDEEEVNADLAARRRKLEDECTELKKDI 1003 Query: 961 DDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEE 1020 DDL+LTLAK EKEK ATENKVKNLTEEMA LDE++A+LTKEKKALQEAHQQ L DLQAEE Sbjct: 1004 DDLKLTLAKAEKEKQATENKVKNLTEEMAALDESVARLTKEKKALQEAHQQALGDLQAEE 1063 Query: 1021 DKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQ 1080 D+V+ LTKAK++LEQQV+DLE SLEQEKKLRMD ERAKRKLEGDLKL QES+ D +KQ Sbjct: 1064 DRVSALTKAKLRLEQQVEDLECSLEQEKKLRMDTERAKRKLEGDLKLTQESVADAAQDKQ 1123 Query: 1081 QLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEK 1140 QL+EKLKKK+ E+S L ++EDEQ LG Q+QKKIKELQAR EELEEE+EAERA+RA+ EK Sbjct: 1124 QLEEKLKKKDSELSQLSLRVEDEQLLGAQMQKKIKELQARAEELEEELEAERAARARVEK 1183 Query: 1141 QRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRK 1200 QR++ +RELEE+SERLEEAGGA++ Q E +KREAE ++RR+LEEA L+HEAT A LR+ Sbjct: 1184 QRAEAARELEELSERLEEAGGASAGQREGCRKREAELGRLRRELEEAALRHEATVAALRR 1243 Query: 1201 KHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLED 1260 K A+ AELGEQ+D+LQRV+QKLEKEKSE++ME+DDLA+NVET+++AK + EK+CRT ED Sbjct: 1244 KQAEGAAELGEQVDSLQRVRQKLEKEKSELRMEVDDLAANVETLTRAKASAEKLCRTYED 1303 Query: 1261 QLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEE 1320 QLSE K K EE QR + D + QRGRLQTESGE SR L+EKE L+SQLSRGK Q +EE Sbjct: 1304 QLSEAKIKVEELQRQLADASTQRGRLQTESGELSRLLEEKECLISQLSRGKALAAQSLEE 1363 Query: 1321 LKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTK 1380 L+RQLEEE KAK+ALAHA+Q+ RHDCDLLREQ+EEE E++AELQR LSKAN EVAQWR+K Sbjct: 1364 LRRQLEEESKAKSALAHAVQALRHDCDLLREQHEEEAEAQAELQRLLSKANAEVAQWRSK 1423 Query: 1381 YETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVER 1440 YE DAIQRTEELEEAKKKLA RLQ AEE VEA NAKC+SLEK K RLQ E ED+ L++ER Sbjct: 1424 YEADAIQRTEELEEAKKKLALRLQEAEEGVEAANAKCSSLEKAKLRLQTESEDVTLELER 1483 Query: 1441 TNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQ 1500 +A AALDKKQR+ ++ L E +++ EE ELEA+Q+E+R LGTELF++++ +EE+L+ Sbjct: 1484 ATSAAAALDKKQRHLERALEERRRQEEEMQRELEAAQRESRGLGTELFRLRHGHEEALEA 1543 Query: 1501 LETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHE 1560 LETLKRENKNLQ+EISDLT+Q++ GK I ELEK KK +E EK E+QAALEEAE +LE E Sbjct: 1544 LETLKRENKNLQEEISDLTDQVSLSGKSIQELEKTKKALEGEKSEIQAALEEAEGALELE 1603 Query: 1561 EGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRL 1620 E K LRIQLEL+QVK+EVDRK+AEKDEE L+RNH R VES+Q++LDAE R+RN+A+RL Sbjct: 1604 ETKTLRIQLELSQVKAEVDRKLAEKDEECANLRRNHQRAVESLQASLDAETRARNEALRL 1663 Query: 1621 KKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMV 1680 KKKMEGDLN++E+QL HA R A EA R Q LK+ Q D+ R +L EQ + Sbjct: 1664 KKKMEGDLNDLELQLGHATRQATEAQAATRLMQAQLKEEQAGRDEEQRLAAELHEQAQAL 1723 Query: 1681 ERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDI 1740 ERRA+LL AE+EELRA LEQ ERSR++AEQELL+A+ER+ LLH+QNT L+N KKKLE D+ Sbjct: 1724 ERRASLLAAELEELRAALEQGERSRRLAEQELLEATERLNLLHSQNTGLLNQKKKLEADL 1783 Query: 1741 SQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQ 1800 +Q+ GE+E+ QE R AEEKAKKAITDAAMMAEELKKEQDTSAHLERMKK +EQTV++LQ Sbjct: 1784 AQLSGEVEEAAQERREAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKTLEQTVRELQ 1843 Query: 1801 LRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQT 1860 RL+EAEQ AL+GGKKQ+QKLEA+VRELE E+++EQK++AEA+KG+RKHERRVKEL YQ Sbjct: 1844 ARLEEAEQAALRGGKKQVQKLEAKVRELEAELDAEQKKHAEALKGVRKHERRVKELAYQA 1903 Query: 1861 EEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAE 1920 EEDRKN+ R+QDLVDKLQ+KVKSYKRQ EEAE+Q+NTNLAK+RK QHEL++AEERAD+AE Sbjct: 1904 EEDRKNLARMQDLVDKLQSKVKSYKRQFEEAEQQANTNLAKYRKAQHELDDAEERADMAE 1963 Query: 1921 SQVNKLRVKSRE 1932 +Q NKLR ++R+ Sbjct: 1964 TQANKLRARTRD 1975 Score = 218 bits (555), Expect = 5e-56 Identities = 203/926 (21%), Positives = 424/926 (45%), Gaps = 56/926 (6%) Query: 1031 IKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQ-------ESIMDIENEKQQLD 1083 +KL ++ L S + E++L L R L G L A+ E+ + I EK L Sbjct: 879 MKLFFKMKPLLRSAQAEEELAA-LRAELRGLRGALAAAEAKRQELEETHVSITQEKNDLA 937 Query: 1084 EKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRA-KAEKQR 1142 +L+ ++ +++ + + +QL+ K+KEL R+E+ EEE+ A+ A+R K E + Sbjct: 938 LQLQAEQDNLADAEERCHLLIKSKVQLEGKVKELSERLED-EEEVNADLAARRRKLEDEC 996 Query: 1143 SDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKH 1202 ++L ++++++ L +A K+++A K++ EE E+ A ++K Sbjct: 997 TELKKDIDDLKLTLAKA----------EKEKQATENKVKNLTEEMAALDESVARLTKEKK 1046 Query: 1203 ADSVAELGEQIDNLQRVKQK---LEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLE 1259 A A + + +LQ + + L K K ++ +++DL ++E K + + E+ R LE Sbjct: 1047 ALQEAHQ-QALGDLQAEEDRVSALTKAKLRLEQQVEDLECSLEQEKKLRMDTERAKRKLE 1105 Query: 1260 DQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIE 1319 L + + + L + + +E + S ++++++ L +Q+ + + + E Sbjct: 1106 GDLKLTQESVADAAQDKQQLEEKLKKKDSELSQLSLRVEDEQLLGAQMQKKIKELQARAE 1165 Query: 1320 ELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRT 1379 EL+ +LE E A+ + + + + L E+ EE + A + K E+ + R Sbjct: 1166 ELEEELEAERAARARVEKQRAEAARELEELSERLEEAGGASAGQREGCRKREAELGRLRR 1225 Query: 1380 KYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVE 1439 + E A++ + ++K A+ E V+++ LEK K L+ EV+DL +VE Sbjct: 1226 ELEEAALRHEATVAALRRKQAEGAAELGEQVDSLQRVRQKLEKEKSELRMEVDDLAANVE 1285 Query: 1440 RTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLD 1499 A A+ +K R ++ L+E K K EE +L + + L TE ++ EE Sbjct: 1286 TLTRAKASAEKLCRTYEDQLSEAKIKVEELQRQLADASTQRGRLQTESGELSRLLEEKEC 1345 Query: 1500 QLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEH 1559 + L R Q + +L Q+ E K L + + + C+L E EA + Sbjct: 1346 LISQLSRGKALAAQSLEELRRQLEEESKAKSALAHAVQALRHD-CDLLREQHEEEAEAQA 1404 Query: 1560 EEGKIL-RIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAI 1618 E ++L + E+ Q +S+ + ++ EE+++ K+ ++ + ++A + Sbjct: 1405 ELQRLLSKANAEVAQWRSKYEADAIQRTEELEEAKKKLALRLQEAEEGVEAANAKCSSLE 1464 Query: 1619 RLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLA 1678 + K +++ + ++ ++L A AA + R+ + L++ + R +E+++ +L Sbjct: 1465 KAKLRLQTESEDVTLELERATSAAAALDKKQRHLERALEERR-------RQEEEMQRELE 1517 Query: 1679 MVERRANLLQAEI-------EELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLIN 1731 +R + L E+ EE LE +R K ++E+ D +++V L L Sbjct: 1518 AAQRESRGLGTELFRLRHGHEEALEALETLKRENKNLQEEISDLTDQVSLSGKSIQELEK 1577 Query: 1732 TKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEEL-KKEQDTSAHLERMKK 1790 TKK LE + S++Q +E+ E K + + + + E+ +K + +++ Sbjct: 1578 TKKALEGEKSEIQAALEEAEGALELEETKTLRIQLELSQVKAEVDRKLAEKDEECANLRR 1637 Query: 1791 NMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHE 1850 N ++ V+ LQ LD AE A + +K+E + +LE ++ ++ EA R + Sbjct: 1638 NHQRAVESLQASLD-AETRARNEALRLKKKMEGDLNDLELQLGHATRQATEAQAATRLMQ 1696 Query: 1851 RRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELE 1910 ++KE +E+++ L + QA+ E +++ A+ +L+ LE Sbjct: 1697 AQLKEEQAGRDEEQRLAAELHE--------------QAQALERRASLLAAELEELRAALE 1742 Query: 1911 EAEERADIAESQVNKLRVKSREVHTK 1936 + E +AE ++ + + +H++ Sbjct: 1743 QGERSRRLAEQELLEATERLNLLHSQ 1768 Score = 144 bits (363), Expect = 8e-34 Identities = 188/810 (23%), Positives = 336/810 (41%), Gaps = 96/810 (11%) Query: 1177 FQKMRRDLEEATLQHEATA--ATLRK-KHADSVAELGEQIDNLQRVKQKLEKEKSEMKME 1233 F KM+ L A + E A A LR + A + AE Q L+ + +EK+++ ++ Sbjct: 882 FFKMKPLLRSAQAEEELAALRAELRGLRGALAAAEAKRQ--ELEETHVSITQEKNDLALQ 939 Query: 1234 IDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEF 1293 + N+ + L K LE ++ EL + E+++ + DL A+R +L+ E E Sbjct: 940 LQAEQDNLADAEERCHLLIKSKVQLEGKVKELSERLEDEEEVNADLAARRRKLEDECTEL 999 Query: 1294 SRQLDEKEALVSQLSRGKQAFTQQIEELKRQ---LEEEI----KAKNALAHALQSSRHDC 1346 + +D+ + +++ + KQA +++ L + L+E + K K AL A Q + D Sbjct: 1000 KKDIDDLKLTLAKAEKEKQATENKVKNLTEEMAALDESVARLTKEKKALQEAHQQALGDL 1059 Query: 1347 DLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTE---ELEEAKKKLAQRL 1403 Q EE++ S AL+KA + Q E Q + + E AK+KL L Sbjct: 1060 -----QAEEDRVS------ALTKAKLRLEQQVEDLECSLEQEKKLRMDTERAKRKLEGDL 1108 Query: 1404 QAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWK 1463 + +E V LE+ ++ +E+ L L VE A + KK + E + Sbjct: 1109 KLTQESVADAAQDKQQLEEKLKKKDSELSQLSLRVEDEQLLGAQMQKK-------IKELQ 1161 Query: 1464 QKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIA 1523 + EE ELEA + + + + EE ++LE + ++ ++ A Sbjct: 1162 ARAEELEEELEAERAARARVEKQRAEAARELEELSERLEEAGGASAGQRE---GCRKREA 1218 Query: 1524 EGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIA 1583 E G+ ELE+ + E L+ E A L + + R++ +L + KSE+ Sbjct: 1219 ELGRLRRELEEAALRHEATVAALRRKQAEGAAELGEQVDSLQRVRQKLEKEKSELRM--- 1275 Query: 1584 EKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAA 1643 E+D L N VE++ R++ A +L + E L+E +I++ R A Sbjct: 1276 ----EVDDLAAN----VETLT-------RAKASAEKLCRTYEDQLSEAKIKVEELQRQLA 1320 Query: 1644 EALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTER 1703 +A +G L+ L L +E L QL+ R L +EELR LE+ + Sbjct: 1321 DA----STQRGRLQTESGELSRLLEEKECLISQLS---RGKALAAQSLEELRRQLEEESK 1373 Query: 1704 SRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQMQGEME--------DILQEAR 1755 ++ + LL Q+ + +L+ +S+ E+ D +Q Sbjct: 1374 AKSALAHAVQALRHDCDLLREQHEEEAEAQAELQRLLSKANAEVAQWRSKYEADAIQRTE 1433 Query: 1756 NAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGK 1815 EE KK E ++ + LE+ K ++ +D+ L L+ A A K Sbjct: 1434 ELEEAKKKLALRLQEAEEGVEAANAKCSSLEKAKLRLQTESEDVTLELERATSAAAALDK 1493 Query: 1816 KQI---QKLEARVR---ELEGEVESEQKRNA-----------------EAVKGLRKHERR 1852 KQ + LE R R E++ E+E+ Q+ + EA++ L++ + Sbjct: 1494 KQRHLERALEERRRQEEEMQRELEAAQRESRGLGTELFRLRHGHEEALEALETLKRENKN 1553 Query: 1853 VKE----LTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHE 1908 ++E LT Q K+I L+ L+ + + EEAE K ++Q E Sbjct: 1554 LQEEISDLTDQVSLSGKSIQELEKTKKALEGEKSEIQAALEEAEGALELEETKTLRIQLE 1613 Query: 1909 LEEAEERADIAESQVNKLRVKSREVHTKVI 1938 L + + D ++ ++ R H + + Sbjct: 1614 LSQVKAEVDRKLAEKDEECANLRRNHQRAV 1643 >gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens] Length = 1946 Score = 2318 bits (6008), Expect = 0.0 Identities = 1157/1936 (59%), Positives = 1536/1936 (79%), Gaps = 12/1936 (0%) Query: 6 ELAVFGEAAPFLRKSERERIEAQNRPFDAKTSVFVAEPKESFVKGTIQ-SREGGKVTVKT 64 +L+ GEAA FLR+SE E + Q D K ++ + + ++++ ++ S + G V V+T Sbjct: 22 DLSDLGEAAAFLRRSEAELLLLQATALDGKKKCWIPDGENAYIEAEVKGSEDDGTVIVET 81 Query: 65 EGGATLTVKDDQVFPMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCV 124 G +L++K+D++ MNPP+++ IEDMAM+THL+E +VL+ LK RY WMIYTYSGLFCV Sbjct: 82 ADGESLSIKEDKIQQMNPPEFEMIEDMAMLTHLNEASVLHTLKRRYGQWMIYTYSGLFCV 141 Query: 125 TVNPYKWLPVYKPEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAG 184 T+NPYKWLPVY+ EV+ AY+GK+R EAPPHIF++++NA+Q ML +RENQSIL TGESGAG Sbjct: 142 TINPYKWLPVYQKEVMAAYKGKRRSEAPPHIFAVANNAFQDMLHNRENQSILFTGESGAG 201 Query: 185 KTVNTKRVIQYFATIAVTGEKKKEEITSGKIQGTLEDQIISANPLLEAFGNAKTVRNDNS 244 KTVN+K +IQYFATIA E +K+ QG LEDQI+ AN +LEAFGNAKT+RNDNS Sbjct: 202 KTVNSKHIIQYFATIAAMIESRKK-------QGALEDQIMQANTILEAFGNAKTLRNDNS 254 Query: 245 SRFGKFIRIHFGTTGKLASADIETYLLEKSRVVFQLKAERSYHIFYQITSNKKPELIEML 304 SRFGKFIR+HFG G L+S DI+ YLLEKSRV+FQ ER+YHIFYQI S +K EL ++L Sbjct: 255 SRFGKFIRMHFGARGMLSSVDIDIYLLEKSRVIFQQAGERNYHIFYQILSGQK-ELHDLL 313 Query: 305 LITTNPYDYPFVSQGEISVASIDDQEELMATDSAIDILGFTNEEKVSIYKLTGAVMHYGN 364 L++ NP D+ F S G ++V S+DD EEL+AT+ A+DILGF +EK YKLTGA+MH+GN Sbjct: 314 LVSANPSDFHFCSCGAVTVESLDDAEELLATEQAMDILGFLPDEKYGCYKLTGAIMHFGN 373 Query: 365 LKFKQKQREEQAEPDGTEVADKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTVEQVS 424 +KFKQK REEQ E DGTE ADKAA+L +NS++L+K L +PR+KVGNEYVT+GQT+EQV+ Sbjct: 374 MKFKQKPREEQLEADGTENADKAAFLMGINSSELVKCLIHPRIKVGNEYVTRGQTIEQVT 433 Query: 425 NAVGALAKAVYEKMFLWMVARINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFT 484 AVGAL+K++YE+MF W+VARIN+ LD K RQ+FIG+LDI GFEI ++NSLEQLCINFT Sbjct: 434 CAVGALSKSMYERMFKWLVARINRALDAKLSRQFFIGILDITGFEILEYNSLEQLCINFT 493 Query: 485 NEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEECMFP 544 NEKLQQFFN HMFVLEQEEYKKE IEW I FG+DL ACI+LIEKPMGI SILEEECMFP Sbjct: 494 NEKLQQFFNWHMFVLEQEEYKKESIEWVSIGFGLDLQACIDLIEKPMGILSILEEECMFP 553 Query: 545 KATDTSFKNKLYDQHLGKSANFQKPKVVKGKAEAHFALIHYAGVVDYNITGWLEKNKDPL 604 KATD +FK KL+D H GKS + QKPK K K EAHF L+HYAGVV YNI+GWLEKNKD L Sbjct: 554 KATDLTFKTKLFDNHFGKSVHLQKPKPDKKKFEAHFELVHYAGVVPYNISGWLEKNKDLL 613 Query: 605 NETVVGLYQKSAMKTLAQLFSGAQTAEGEGAGGGAKKGGKKKGSSFQTVSALFRENLNKL 664 NETVV ++QKS+ + LA LF + + G K+ KKG+SFQTV++L +ENLNKL Sbjct: 614 NETVVAVFQKSSNRLLASLFENYMSTDSAIPFGEKKR---KKGASFQTVASLHKENLNKL 670 Query: 665 MTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADF 724 MTNL+ST PHFVRCI PN K PG ++ LVL QLRCNGVLEG RICR+GFP+R+ YADF Sbjct: 671 MTNLKSTAPHFVRCINPNVNKIPGILDPYLVLQQLRCNGVLEGTRICREGFPNRLQYADF 730 Query: 725 KQRYKVLNASAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRD 784 KQRY +LN P+ +F+ S+KA+E+LL S++IDHTQY+FG TKVFFKAG LG LE +RD Sbjct: 731 KQRYCILNPRTFPKSKFVSSRKAAEELLGSLEIDHTQYRFGITKVFFKAGFLGQLEAIRD 790 Query: 785 DKLAQLITRTQARCRGFLARVEYQRMVERREAIFCIQYNIRSFMNVKHWPWMKLFFKIKP 844 ++L+++ T QAR +G L R+++Q+++E R+A+ IQ+NIR+FM VK+WPWM+LFFKIKP Sbjct: 791 ERLSKVFTLFQARAQGKLMRIKFQKILEERDALILIQWNIRAFMAVKNWPWMRLFFKIKP 850 Query: 845 LLKSAETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGL 904 L+KS+E +E+A +KEE +++ L KSE +R+EL+ K V+L +EKNDL LQ+QAE E L Sbjct: 851 LVKSSEVGEEVAGLKEECAQLQKALEKSEFQREELKAKQVSLTQEKNDLILQLQAEQETL 910 Query: 905 ADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLE 964 A+ EE+C+ LIK+KIQLEA++KE++ER E+EEEIN+ELTA+ RKLEDEC ELKK+IDDLE Sbjct: 911 ANVEEQCEWLIKSKIQLEARVKELSERVEEEEEINSELTARGRKLEDECFELKKEIDDLE 970 Query: 965 LTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVN 1024 L K EKEK TE+KVKNLTEE+ L+E I+KL + K +QEAHQQTLDDL EE+K++ Sbjct: 971 TMLVKSEKEKRTTEHKVKNLTEEVEFLNEDISKLNRAAKVVQEAHQQTLDDLHMEEEKLS 1030 Query: 1025 TLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDE 1084 +L+KA +KLEQQVD+LEG+LEQE+K RM+ ER KLEG+LKL +ES+ ++E+ ++ L E Sbjct: 1031 SLSKANLKLEQQVDELEGALEQERKARMNCERELHKLEGNLKLNRESMENLESSQRHLAE 1090 Query: 1085 KLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSD 1144 +L+KKE E+S + SK+E+E+ L QLQK +KELQ +I++L+E++EAER +RAK E++R+D Sbjct: 1091 ELRKKELELSQMNSKVENEKGLVAQLQKTVKELQTQIKDLKEKLEAERTTRAKMERERAD 1150 Query: 1145 LSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHAD 1204 L+++L +++ERLEE GG++ AQ+E+ KK+E +FQK+ RD+EEATL E T+A+L+K+HAD Sbjct: 1151 LTQDLADLNERLEEVGGSSLAQLEITKKQETKFQKLHRDMEEATLHFETTSASLKKRHAD 1210 Query: 1205 SVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSE 1264 S+AEL Q++NLQ+VKQKLEK+KS++++E+DDL + VE +++AK N EK+C E++L E Sbjct: 1211 SLAELEGQVENLQQVKQKLEKDKSDLQLEVDDLLTRVEQMTRAKANAEKLCTLYEERLHE 1270 Query: 1265 LKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQ 1324 +K ++ +L NDL AQ+ +L +ESGEF R+L+EKEAL++QLSR K FT+QIE+L+ Q Sbjct: 1271 ATAKLDKVTQLANDLAAQKTKLWSESGEFLRRLEEKEALINQLSREKSNFTRQIEDLRGQ 1330 Query: 1325 LEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETD 1384 LE+E K+++ALAHALQ ++ DCDLLREQYEEEQE KAEL R LSK N E+ QWR KYE + Sbjct: 1331 LEKETKSQSALAHALQKAQRDCDLLREQYEEEQEVKAELHRTLSKVNAEMVQWRMKYENN 1390 Query: 1385 AIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAA 1444 IQRTE+LE+AKK+LA RLQ A E + NA+ ASLE+ + +LQ E+ D + D+ + +A Sbjct: 1391 VIQRTEDLEDAKKELAIRLQEAAEAMGVANARNASLERARHQLQLELGDALSDLGKVRSA 1450 Query: 1445 CAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETL 1504 A LD+KQ K LA+WKQK EE+ A L+ASQKE ++L TEL K+KN YEES+ ETL Sbjct: 1451 AARLDQKQLQSGKALADWKQKHEESQALLDASQKEVQALSTELLKLKNTYEESIVGQETL 1510 Query: 1505 KRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKI 1564 +RENKNLQ+EIS+LT Q+ EG K + E+EK+KK +E+EK E+Q LEE E +LE E KI Sbjct: 1511 RRENKNLQEEISNLTNQVREGTKNLTEMEKVKKLIEEEKTEVQVTLEETEGALERNESKI 1570 Query: 1565 LRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKM 1624 L QLEL + K+E++RK++EKDEEI+ +R ++S+QS+LD+E +SR + RLKKKM Sbjct: 1571 LHFQLELLEAKAELERKLSEKDEEIENFRRKQQCTIDSLQSSLDSEAKSRIEVTRLKKKM 1630 Query: 1625 EGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRA 1684 E DLNEME+QL+ ANR +EA ++ Q +KD Q+ LDD+ + DLKEQ+A+ ERR Sbjct: 1631 EEDLNEMELQLSCANRQVSEATKSLGQLQIQIKDLQMQLDDSTQLNSDLKEQVAVAERRN 1690 Query: 1685 NLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQMQ 1744 +LLQ+E+E+LR+ EQTER R+++E+ELL+A+ER+ L +TQNTSL++ KKKLE D+++MQ Sbjct: 1691 SLLQSELEDLRSLQEQTERGRRLSEEELLEATERINLFYTQNTSLLSQKKKLEADVARMQ 1750 Query: 1745 GEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLD 1804 E E+++QE +NAEEKAKKA +AA ++EELKK+QDT AHLER ++NMEQT+ DLQ RL Sbjct: 1751 KEAEEVVQECQNAEEKAKKAAIEAANLSEELKKKQDTIAHLERTRENMEQTITDLQKRLA 1810 Query: 1805 EAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDR 1864 EAEQ+AL G +KQIQKLE+RVRELEGE+E E +R+AEA +G R+ ER +KELTYQ EED+ Sbjct: 1811 EAEQMALMGSRKQIQKLESRVRELEGELEGEIRRSAEAQRGARRLERCIKELTYQAEEDK 1870 Query: 1865 KNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAESQVN 1924 KN+ R+Q +DKLQ KV++YK+Q E AE Q+N L+K++K QHEL E +ERA++AESQVN Sbjct: 1871 KNLSRMQTQMDKLQLKVQNYKQQVEVAETQANQYLSKYKKQQHELNEVKERAEVAESQVN 1930 Query: 1925 KLRVKSREVHTKVISE 1940 KL++K+RE KV E Sbjct: 1931 KLKIKAREFGKKVQEE 1946 >gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo sapiens] Length = 1972 Score = 1423 bits (3683), Expect = 0.0 Identities = 779/1908 (40%), Positives = 1181/1908 (61%), Gaps = 20/1908 (1%) Query: 34 AKTSVFVAEPKESFVKGTIQSREGGKVTVK-TEGGATLTVKDDQVFPMNPPKYDKIEDMA 92 AK V+V K+ F +I+ +G +V V+ E G +TV D + MNPPK+ K+EDMA Sbjct: 32 AKRLVWVPSEKQGFEAASIKEEKGDEVVVELVENGKKVTVGKDDIQKMNPPKFSKVEDMA 91 Query: 93 MMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYKPEVVTAYRGKKRQEAP 152 +T L+E +VL+NL+ERY + +IYTYSGLFCV VNPYK LP+Y ++V Y+GKKR E P Sbjct: 92 ELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKRHEMP 151 Query: 153 PHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKEEITS 212 PHI++I+D AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY A +A + + KK+ Sbjct: 152 PHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKDT--- 208 Query: 213 GKIQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLE 272 I G LE Q++ ANP+LEAFGNAKTV+NDNSSRFGKFIRI+F TG + A+IETYLLE Sbjct: 209 -SITGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLE 267 Query: 273 KSRVVFQLKAERSYHIFYQITSNKKPELIEMLLITTNPYDYPFVSQGEISVASIDDQEEL 332 KSR + Q + ER++HIFY + + K ++ LL+ +Y F+S G + + + D E Sbjct: 268 KSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLE-GFNNYTFLSNGFVPIPAAQDDEMF 326 Query: 333 MATDSAIDILGFTNEEKVSIYKLTGAVMHYGNLKFKQKQREEQAEPDGTEVADKAAYLQS 392 T A+ I+GF+ EE++SI K+ +V+ GN+ FK+++ +QA A K +L Sbjct: 327 QETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKVCHLMG 386 Query: 393 LNSADLLKALCYPRVKVGNEYVTKGQTVEQVSNAVGALAKAVYEKMFLWMVARINQQLD- 451 +N D +++ PR+KVG + V K QT EQ AV ALAKA YE++F W++ R+N+ LD Sbjct: 387 INVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRVNKALDK 446 Query: 452 TKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEW 511 T + F+G+LDIAGFEIF+ NS EQLCIN+TNEKLQQ FNH MF+LEQEEY++EGIEW Sbjct: 447 THRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEW 506 Query: 512 TFIDFGMDLAACIELIEKPM---GIFSILEEECMFPKATDTSFKNKLYDQHLGKSANFQK 568 FIDFG+DL CIELIE+P G+ ++L+EEC FPKATD SF KL + G FQK Sbjct: 507 NFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQ-GSHPKFQK 565 Query: 569 PKVVKGKAEAHFALIHYAGVVDYNITGWLEKNKDPLNETVVGLYQKSAMKTLAQLFSGAQ 628 PK +K K E F++IHYAG VDYN + WL KN DPLN+ V L S+ K +A L+ Sbjct: 566 PKQLKDKTE--FSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLWKDVD 623 Query: 629 TAEG-----EGAGGGAKKGGKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPNE 683 G + K K F+TV L++E L KLMT LR+T P+FVRCIIPN Sbjct: 624 RIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCIIPNH 683 Query: 684 TKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQFID 743 K G ++ LVL QLRCNGVLEGIRICR+GFP+RI++ +F+QRY++L A+AIP+G F+D Sbjct: 684 EKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKG-FMD 742 Query: 744 SKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDDKLAQLITRTQARCRGFLA 803 K+A ++ ++++D Y+ G +K+FF+ G+L LEE RD K+ +I QA CRG+LA Sbjct: 743 GKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRGYLA 802 Query: 804 RVEYQRMVERREAIFCIQYNIRSFMNVKHWPWMKLFFKIKPLLKSAETEKEMATMKEEFQ 863 R + + ++ A+ IQ N +++ +++W W +LF K+KPLL+ E+EM ++E Q Sbjct: 803 RKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKEDELQ 862 Query: 864 KIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCDQLIKTKIQLEA 923 K K+ K+E + KELE+K L +EKN LQ Q+QAE E A+AEE +L K +LE Sbjct: 863 KTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEE 922 Query: 924 KIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKN 983 + E+ R E+EE+ +L A+++K+ + +L++ +++ E K++ EK E K+K Sbjct: 923 ILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKK 982 Query: 984 LTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGS 1043 L +E+ +D+ KL+KE+K L+E +L EE+K LTK K K E + +LE Sbjct: 983 LEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVR 1042 Query: 1044 LEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDE 1103 L++E+K R +LE+ KRKLEGD E I D++ + +L +L KKE E+ ++++DE Sbjct: 1043 LKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDE 1102 Query: 1104 QALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGAT 1163 A KKI+EL+ I +L+E++++ERA+R KAEKQ+ DL ELE + LE+ +T Sbjct: 1103 IAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDST 1162 Query: 1164 SAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKL 1223 + Q E+ KRE E +++ L+E T HEA +R+KHA +V EL EQ++ +R K L Sbjct: 1163 ATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANL 1222 Query: 1224 EKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQR 1283 +K K ++ E DLA + + +AK +E + LE Q+ EL+SK + +R +L + Sbjct: 1223 DKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKV 1282 Query: 1284 GRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSR 1343 +LQ E + L+E E +L++ + + Q+++ + L+EE + K ++ L+ Sbjct: 1283 HKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLE 1342 Query: 1344 HDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRL 1403 + + L++Q +EE E+K L+R +S N +++ + K + D E LEE KK+ + + Sbjct: 1343 EERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQ-DFASTVEALEEGKKRFQKEI 1401 Query: 1404 QAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWK 1463 + + E A LEKTK RLQ E++DL++D++ + L+KKQR FD++LAE K Sbjct: 1402 ENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEK 1461 Query: 1464 QKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIA 1523 + E + ++ EAR T+ + A EE+L+ E L+R NK L+ E+ DL Sbjct: 1462 NISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKD 1521 Query: 1524 EGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIA 1583 + GK +HELEK K+ +E + E++ LEE E L+ E LR+++ + +K + +R + Sbjct: 1522 DVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQ 1581 Query: 1584 EKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAA 1643 +DE+ ++ +R R + ++ L+ E + R A KKK+EGDL ++E+Q + A + Sbjct: 1582 ARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGRE 1641 Query: 1644 EALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTER 1703 EA++ R Q +KD Q L+DA S++++ E++A L+A++ +L+ L ER Sbjct: 1642 EAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAER 1701 Query: 1704 SRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKK 1763 +RK A+ E + +E + + +L + K++LE I+Q++ E+E+ ++ +K Sbjct: 1702 ARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRK 1761 Query: 1764 AITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEA 1823 A A ++ EL E+ T+ E ++ +E+ K+L+ +L E E K I LEA Sbjct: 1762 ATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEA 1821 Query: 1824 RVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKS 1883 ++ +LE +VE E + A K L++ ++++KE+ Q E++RK + ++ +K A+VK Sbjct: 1822 KIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQ 1881 Query: 1884 YKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAESQVNKLRVKSR 1931 KRQ EEAEE+S A RKLQ EL+EA E + +VN L+ K R Sbjct: 1882 LKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLR 1929 Score = 216 bits (549), Expect = 2e-55 Identities = 189/902 (20%), Positives = 433/902 (48%), Gaps = 53/902 (5%) Query: 1083 DEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQR 1142 +E+++ KE E+ + + + + +L++K +L L+E+++AE A+AE+ R Sbjct: 851 EEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMR 910 Query: 1143 SDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRR---DLEEATLQHEATAATLR 1199 L+ + +E+ E L E + + ++ +AE +KM + DLEE + EA L+ Sbjct: 911 VRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQ 970 Query: 1200 KKHADSVAE---LGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCR 1256 + + A+ L ++I + KL KE+ ++ I DL +N+ + NL K+ Sbjct: 971 LEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKN 1030 Query: 1257 TLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQ 1316 E +SEL+ + +++++ +L + +L+ ++ +F Q+ + +A +++L + Sbjct: 1031 KHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEE 1090 Query: 1317 QIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQ 1376 +++ +L++EI KN ++ L+E + E+ ++ + ++ E+ Sbjct: 1091 ELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEA 1150 Query: 1377 WRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHV-EAVNAKCASLEKTKQRLQNEVEDLM 1435 +T+ E D + T +E + K Q + ++ + E + A +++ +Q+ VE+L Sbjct: 1151 LKTELE-DTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELT 1209 Query: 1436 LDVERTNAACAALDKKQRNFDK----------ILAEWKQKCEETHAELEASQKEARS--- 1482 +E+ A A LDK ++ +K +L + KQ+ E +LEA +E +S Sbjct: 1210 EQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCS 1269 Query: 1483 --------LGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEK 1534 L ++ K++N E L + + L ++++ L+ Q+ + + + E + Sbjct: 1270 DGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETR 1329 Query: 1535 IK-------KQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDE 1587 K +Q+E+E+ LQ L+E + ++ E I + ++L+ K ++ + A E Sbjct: 1330 QKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKL-QDFASTVE 1388 Query: 1588 EIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALR 1647 +++ K+ + +E++ + + + + + K +++ +L+++ + L++ ++ + + Sbjct: 1389 ALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEK 1448 Query: 1648 NYRNTQGILKD----TQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTER 1703 R +L + + + D+ R++ + +E+ E +A L +EE E+ ER Sbjct: 1449 KQRKFDQLLAEEKNISSKYADERDRAEAEAREK----ETKALSLARALEEALEAKEELER 1504 Query: 1704 SRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEE-KAK 1762 + K+ + E+ D + L +K+ LET + +M+ ++E++ E + E+ K + Sbjct: 1505 TNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLR 1564 Query: 1763 KAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRL-DEAEQLALKGGKKQIQKL 1821 + A+ + + Q E ++ +++ + + + L DE +Q AL K+ KL Sbjct: 1565 LEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKK--KL 1622 Query: 1822 EARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKV 1881 E +++LE + +S K EA+K LRK + ++K+ + E+ R + + + + K Sbjct: 1623 EGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKA 1682 Query: 1882 KSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAESQV--NKLRVKSREVHTKVIS 1939 KS +A+ + Q + A+ + Q +LE+ E ++A S N L+ + R + ++ Sbjct: 1683 KSL--EADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQ 1740 Query: 1940 EE 1941 E Sbjct: 1741 LE 1742 Score = 96.3 bits (238), Expect = 3e-19 Identities = 78/366 (21%), Positives = 165/366 (45%), Gaps = 44/366 (12%) Query: 847 KSAETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLAD 906 K + ++++ + E + + + A + A +K+LE + DL+LQ + +G + Sbjct: 1590 KRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDL-------KDLELQADSAIKGREE 1642 Query: 907 AEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELT 966 A IK +L+A++K+ ED E+ A ++ E + L+ D+ L+ Sbjct: 1643 A-------IKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQED 1695 Query: 967 LAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTL 1026 LA E+ + + + + L EE+A L EK+ L+ Q ++L+ E+ + + Sbjct: 1696 LAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAM 1755 Query: 1027 TKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENE-------- 1078 + K QQ + L L E+ E A+++LE K + + ++E Sbjct: 1756 SDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKST 1815 Query: 1079 -----------KQQLDEK----------LKKKEFEISNLQSKIEDEQALGIQLQKKIKEL 1117 ++Q++++ LK+K+ ++ + ++EDE+ + Q +++ ++ Sbjct: 1816 IAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKG 1875 Query: 1118 QARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSA-QIEMNKKREAE 1176 AR+++L+ ++E + R L REL+E +E E G +A + ++ + E Sbjct: 1876 NARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLRRGNETS 1935 Query: 1177 FQKMRR 1182 F RR Sbjct: 1936 FVPSRR 1941 Score = 75.5 bits (184), Expect = 5e-13 Identities = 59/271 (21%), Positives = 119/271 (43%), Gaps = 8/271 (2%) Query: 1668 RSQEDLK---EQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHT 1724 R +E+++ ++L + R + E++EL Q + + +++L +E Sbjct: 849 RQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEE 908 Query: 1725 QNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAH 1784 L K++LE + +M+ +E+ + + + KK + E+L++E+ Sbjct: 909 MRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQK 968 Query: 1785 LERMKKNMEQTVKDLQLRLDEAEQLALKGGK--KQIQKLEARVRELEGEVESEQKRNAEA 1842 L+ K E +K L+ DE + + K K+ + LE R+ +L + E+++ Sbjct: 969 LQLEKVTAEAKIKKLE---DEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNL 1025 Query: 1843 VKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKF 1902 K KHE + EL + +++ K+ L+ L KL+ + Q + + Q + Sbjct: 1026 TKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQL 1085 Query: 1903 RKLQHELEEAEERADIAESQVNKLRVKSREV 1933 K + EL+ A R D +Q N K RE+ Sbjct: 1086 AKKEEELQAALARLDDEIAQKNNALKKIREL 1116 >gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo sapiens] Length = 1979 Score = 1423 bits (3683), Expect = 0.0 Identities = 781/1911 (40%), Positives = 1183/1911 (61%), Gaps = 19/1911 (0%) Query: 34 AKTSVFVAEPKESFVKGTIQSREGGKVTVK-TEGGATLTVKDDQVFPMNPPKYDKIEDMA 92 AK V+V K+ F +I+ +G +V V+ E G +TV D + MNPPK+ K+EDMA Sbjct: 32 AKRLVWVPSEKQGFEAASIKEEKGDEVVVELVENGKKVTVGKDDIQKMNPPKFSKVEDMA 91 Query: 93 MMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYKPEVVTAYRGKKRQEAP 152 +T L+E +VL+NL+ERY + +IYTYSGLFCV VNPYK LP+Y ++V Y+GKKR E P Sbjct: 92 ELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKRHEMP 151 Query: 153 PHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKE-EIT 211 PHI++I+D AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY A +A + + KK+ IT Sbjct: 152 PHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKDTSIT 211 Query: 212 SGK--IQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETY 269 G G LE Q++ ANP+LEAFGNAKTV+NDNSSRFGKFIRI+F TG + A+IETY Sbjct: 212 QGPSFAYGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETY 271 Query: 270 LLEKSRVVFQLKAERSYHIFYQITSNKKPELIEMLLITTNPYDYPFVSQGEISVASIDDQ 329 LLEKSR + Q + ER++HIFY + + K ++ LL+ +Y F+S G + + + D Sbjct: 272 LLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLE-GFNNYTFLSNGFVPIPAAQDD 330 Query: 330 EELMATDSAIDILGFTNEEKVSIYKLTGAVMHYGNLKFKQKQREEQAEPDGTEVADKAAY 389 E T A+ I+GF+ EE++SI K+ +V+ GN+ FK+++ +QA A K + Sbjct: 331 EMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKVCH 390 Query: 390 LQSLNSADLLKALCYPRVKVGNEYVTKGQTVEQVSNAVGALAKAVYEKMFLWMVARINQQ 449 L +N D +++ PR+KVG + V K QT EQ AV ALAKA YE++F W++ R+N+ Sbjct: 391 LMGINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRVNKA 450 Query: 450 LD-TKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEG 508 LD T + F+G+LDIAGFEIF+ NS EQLCIN+TNEKLQQ FNH MF+LEQEEY++EG Sbjct: 451 LDKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREG 510 Query: 509 IEWTFIDFGMDLAACIELIEKPM---GIFSILEEECMFPKATDTSFKNKLYDQHLGKSAN 565 IEW FIDFG+DL CIELIE+P G+ ++L+EEC FPKATD SF KL + G Sbjct: 511 IEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQ-GSHPK 569 Query: 566 FQKPKVVKGKAEAHFALIHYAGVVDYNITGWLEKNKDPLNETVVGLYQKSAMKTLAQLFS 625 FQKPK +K K E F++IHYAG VDYN + WL KN DPLN+ V L S+ K +A L+ Sbjct: 570 FQKPKQLKDKTE--FSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLWK 627 Query: 626 GAQTAEG-----EGAGGGAKKGGKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCII 680 G + K K F+TV L++E L KLMT LR+T P+FVRCII Sbjct: 628 DVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCII 687 Query: 681 PNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQ 740 PN K G ++ LVL QLRCNGVLEGIRICR+GFP+RI++ +F+QRY++L A+AIP+G Sbjct: 688 PNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKG- 746 Query: 741 FIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDDKLAQLITRTQARCRG 800 F+D K+A ++ ++++D Y+ G +K+FF+ G+L LEE RD K+ +I QA CRG Sbjct: 747 FMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRG 806 Query: 801 FLARVEYQRMVERREAIFCIQYNIRSFMNVKHWPWMKLFFKIKPLLKSAETEKEMATMKE 860 +LAR + + ++ A+ IQ N +++ +++W W +LF K+KPLL+ E+EM ++ Sbjct: 807 YLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKED 866 Query: 861 EFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCDQLIKTKIQ 920 E QK K+ K+E + KELE+K L +EKN LQ Q+QAE E A+AEE +L K + Sbjct: 867 ELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQE 926 Query: 921 LEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENK 980 LE + E+ R E+EE+ +L A+++K+ + +L++ +++ E K++ EK E K Sbjct: 927 LEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAK 986 Query: 981 VKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDL 1040 +K L +E+ +D+ KL+KE+K L+E +L EE+K LTK K K E + +L Sbjct: 987 IKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISEL 1046 Query: 1041 EGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKI 1100 E L++E+K R +LE+ KRKLEGD E I D++ + +L +L KKE E+ +++ Sbjct: 1047 EVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARL 1106 Query: 1101 EDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAG 1160 +DE A KKI+EL+ I +L+E++++ERA+R KAEKQ+ DL ELE + LE+ Sbjct: 1107 DDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTL 1166 Query: 1161 GATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVK 1220 +T+ Q E+ KRE E +++ L+E T HEA +R+KHA +V EL EQ++ +R K Sbjct: 1167 DSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAK 1226 Query: 1221 QKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLT 1280 L+K K ++ E DLA + + +AK +E + LE Q+ EL+SK + +R +L Sbjct: 1227 ANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELN 1286 Query: 1281 AQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQ 1340 + +LQ E + L+E E +L++ + + Q+++ + L+EE + K ++ L+ Sbjct: 1287 DKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLR 1346 Query: 1341 SSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLA 1400 + + L++Q +EE E+K L+R +S N +++ + K + D E LEE KK+ Sbjct: 1347 QLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQ-DFASTVEALEEGKKRFQ 1405 Query: 1401 QRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILA 1460 + ++ + E A LEKTK RLQ E++DL++D++ + L+KKQR FD++LA Sbjct: 1406 KEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLA 1465 Query: 1461 EWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTE 1520 E K + E + ++ EAR T+ + A EE+L+ E L+R NK L+ E+ DL Sbjct: 1466 EEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVS 1525 Query: 1521 QIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDR 1580 + GK +HELEK K+ +E + E++ LEE E L+ E LR+++ + +K + +R Sbjct: 1526 SKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFER 1585 Query: 1581 KIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANR 1640 + +DE+ ++ +R R + ++ L+ E + R A KKK+EGDL ++E+Q + A + Sbjct: 1586 DLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIK 1645 Query: 1641 MAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQ 1700 EA++ R Q +KD Q L+DA S++++ E++A L+A++ +L+ L Sbjct: 1646 GREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAA 1705 Query: 1701 TERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEK 1760 ER+RK A+ E + +E + + +L + K++LE I+Q++ E+E+ ++ Sbjct: 1706 AERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDR 1765 Query: 1761 AKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQK 1820 +KA A ++ EL E+ T+ E ++ +E+ K+L+ +L E E K I Sbjct: 1766 VRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAA 1825 Query: 1821 LEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAK 1880 LEA++ +LE +VE E + A K L++ ++++KE+ Q E++RK + ++ +K A+ Sbjct: 1826 LEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNAR 1885 Query: 1881 VKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAESQVNKLRVKSR 1931 VK KRQ EEAEE+S A RKLQ EL+EA E + +VN L+ K R Sbjct: 1886 VKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLR 1936 Score = 216 bits (549), Expect = 2e-55 Identities = 189/902 (20%), Positives = 433/902 (48%), Gaps = 53/902 (5%) Query: 1083 DEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQR 1142 +E+++ KE E+ + + + + +L++K +L L+E+++AE A+AE+ R Sbjct: 858 EEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMR 917 Query: 1143 SDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRR---DLEEATLQHEATAATLR 1199 L+ + +E+ E L E + + ++ +AE +KM + DLEE + EA L+ Sbjct: 918 VRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQ 977 Query: 1200 KKHADSVAE---LGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCR 1256 + + A+ L ++I + KL KE+ ++ I DL +N+ + NL K+ Sbjct: 978 LEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKN 1037 Query: 1257 TLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQ 1316 E +SEL+ + +++++ +L + +L+ ++ +F Q+ + +A +++L + Sbjct: 1038 KHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEE 1097 Query: 1317 QIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQ 1376 +++ +L++EI KN ++ L+E + E+ ++ + ++ E+ Sbjct: 1098 ELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEA 1157 Query: 1377 WRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHV-EAVNAKCASLEKTKQRLQNEVEDLM 1435 +T+ E D + T +E + K Q + ++ + E + A +++ +Q+ VE+L Sbjct: 1158 LKTELE-DTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELT 1216 Query: 1436 LDVERTNAACAALDKKQRNFDK----------ILAEWKQKCEETHAELEASQKEARS--- 1482 +E+ A A LDK ++ +K +L + KQ+ E +LEA +E +S Sbjct: 1217 EQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCS 1276 Query: 1483 --------LGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEK 1534 L ++ K++N E L + + L ++++ L+ Q+ + + + E + Sbjct: 1277 DGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETR 1336 Query: 1535 IK-------KQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDE 1587 K +Q+E+E+ LQ L+E + ++ E I + ++L+ K ++ + A E Sbjct: 1337 QKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKL-QDFASTVE 1395 Query: 1588 EIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALR 1647 +++ K+ + +E++ + + + + + K +++ +L+++ + L++ ++ + + Sbjct: 1396 ALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEK 1455 Query: 1648 NYRNTQGILKD----TQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTER 1703 R +L + + + D+ R++ + +E+ E +A L +EE E+ ER Sbjct: 1456 KQRKFDQLLAEEKNISSKYADERDRAEAEAREK----ETKALSLARALEEALEAKEELER 1511 Query: 1704 SRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEE-KAK 1762 + K+ + E+ D + L +K+ LET + +M+ ++E++ E + E+ K + Sbjct: 1512 TNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLR 1571 Query: 1763 KAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRL-DEAEQLALKGGKKQIQKL 1821 + A+ + + Q E ++ +++ + + + L DE +Q AL K+ KL Sbjct: 1572 LEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKK--KL 1629 Query: 1822 EARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKV 1881 E +++LE + +S K EA+K LRK + ++K+ + E+ R + + + + K Sbjct: 1630 EGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKA 1689 Query: 1882 KSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAESQV--NKLRVKSREVHTKVIS 1939 KS +A+ + Q + A+ + Q +LE+ E ++A S N L+ + R + ++ Sbjct: 1690 KSL--EADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQ 1747 Query: 1940 EE 1941 E Sbjct: 1748 LE 1749 Score = 96.3 bits (238), Expect = 3e-19 Identities = 78/366 (21%), Positives = 165/366 (45%), Gaps = 44/366 (12%) Query: 847 KSAETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLAD 906 K + ++++ + E + + + A + A +K+LE + DL+LQ + +G + Sbjct: 1597 KRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDL-------KDLELQADSAIKGREE 1649 Query: 907 AEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELT 966 A IK +L+A++K+ ED E+ A ++ E + L+ D+ L+ Sbjct: 1650 A-------IKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQED 1702 Query: 967 LAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTL 1026 LA E+ + + + + L EE+A L EK+ L+ Q ++L+ E+ + + Sbjct: 1703 LAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAM 1762 Query: 1027 TKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENE-------- 1078 + K QQ + L L E+ E A+++LE K + + ++E Sbjct: 1763 SDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKST 1822 Query: 1079 -----------KQQLDEK----------LKKKEFEISNLQSKIEDEQALGIQLQKKIKEL 1117 ++Q++++ LK+K+ ++ + ++EDE+ + Q +++ ++ Sbjct: 1823 IAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKG 1882 Query: 1118 QARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSA-QIEMNKKREAE 1176 AR+++L+ ++E + R L REL+E +E E G +A + ++ + E Sbjct: 1883 NARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLRRGNETS 1942 Query: 1177 FQKMRR 1182 F RR Sbjct: 1943 FVPSRR 1948 Score = 75.5 bits (184), Expect = 5e-13 Identities = 59/271 (21%), Positives = 119/271 (43%), Gaps = 8/271 (2%) Query: 1668 RSQEDLK---EQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHT 1724 R +E+++ ++L + R + E++EL Q + + +++L +E Sbjct: 856 RQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEE 915 Query: 1725 QNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAH 1784 L K++LE + +M+ +E+ + + + KK + E+L++E+ Sbjct: 916 MRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQK 975 Query: 1785 LERMKKNMEQTVKDLQLRLDEAEQLALKGGK--KQIQKLEARVRELEGEVESEQKRNAEA 1842 L+ K E +K L+ DE + + K K+ + LE R+ +L + E+++ Sbjct: 976 LQLEKVTAEAKIKKLE---DEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNL 1032 Query: 1843 VKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKF 1902 K KHE + EL + +++ K+ L+ L KL+ + Q + + Q + Sbjct: 1033 TKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQL 1092 Query: 1903 RKLQHELEEAEERADIAESQVNKLRVKSREV 1933 K + EL+ A R D +Q N K RE+ Sbjct: 1093 AKKEEELQAALARLDDEIAQKNNALKKIREL 1123 >gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo sapiens] Length = 1945 Score = 1423 bits (3683), Expect = 0.0 Identities = 781/1911 (40%), Positives = 1183/1911 (61%), Gaps = 19/1911 (0%) Query: 34 AKTSVFVAEPKESFVKGTIQSREGGKVTVK-TEGGATLTVKDDQVFPMNPPKYDKIEDMA 92 AK V+V K+ F +I+ +G +V V+ E G +TV D + MNPPK+ K+EDMA Sbjct: 32 AKRLVWVPSEKQGFEAASIKEEKGDEVVVELVENGKKVTVGKDDIQKMNPPKFSKVEDMA 91 Query: 93 MMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYKPEVVTAYRGKKRQEAP 152 +T L+E +VL+NL+ERY + +IYTYSGLFCV VNPYK LP+Y ++V Y+GKKR E P Sbjct: 92 ELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKRHEMP 151 Query: 153 PHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKE-EIT 211 PHI++I+D AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY A +A + + KK+ IT Sbjct: 152 PHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKDTSIT 211 Query: 212 SGK--IQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETY 269 G G LE Q++ ANP+LEAFGNAKTV+NDNSSRFGKFIRI+F TG + A+IETY Sbjct: 212 QGPSFAYGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETY 271 Query: 270 LLEKSRVVFQLKAERSYHIFYQITSNKKPELIEMLLITTNPYDYPFVSQGEISVASIDDQ 329 LLEKSR + Q + ER++HIFY + + K ++ LL+ +Y F+S G + + + D Sbjct: 272 LLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLE-GFNNYTFLSNGFVPIPAAQDD 330 Query: 330 EELMATDSAIDILGFTNEEKVSIYKLTGAVMHYGNLKFKQKQREEQAEPDGTEVADKAAY 389 E T A+ I+GF+ EE++SI K+ +V+ GN+ FK+++ +QA A K + Sbjct: 331 EMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKVCH 390 Query: 390 LQSLNSADLLKALCYPRVKVGNEYVTKGQTVEQVSNAVGALAKAVYEKMFLWMVARINQQ 449 L +N D +++ PR+KVG + V K QT EQ AV ALAKA YE++F W++ R+N+ Sbjct: 391 LMGINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRVNKA 450 Query: 450 LD-TKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEG 508 LD T + F+G+LDIAGFEIF+ NS EQLCIN+TNEKLQQ FNH MF+LEQEEY++EG Sbjct: 451 LDKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREG 510 Query: 509 IEWTFIDFGMDLAACIELIEKPM---GIFSILEEECMFPKATDTSFKNKLYDQHLGKSAN 565 IEW FIDFG+DL CIELIE+P G+ ++L+EEC FPKATD SF KL + G Sbjct: 511 IEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQ-GSHPK 569 Query: 566 FQKPKVVKGKAEAHFALIHYAGVVDYNITGWLEKNKDPLNETVVGLYQKSAMKTLAQLFS 625 FQKPK +K K E F++IHYAG VDYN + WL KN DPLN+ V L S+ K +A L+ Sbjct: 570 FQKPKQLKDKTE--FSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLWK 627 Query: 626 GAQTAEG-----EGAGGGAKKGGKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCII 680 G + K K F+TV L++E L KLMT LR+T P+FVRCII Sbjct: 628 DVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCII 687 Query: 681 PNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQ 740 PN K G ++ LVL QLRCNGVLEGIRICR+GFP+RI++ +F+QRY++L A+AIP+G Sbjct: 688 PNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKG- 746 Query: 741 FIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDDKLAQLITRTQARCRG 800 F+D K+A ++ ++++D Y+ G +K+FF+ G+L LEE RD K+ +I QA CRG Sbjct: 747 FMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRG 806 Query: 801 FLARVEYQRMVERREAIFCIQYNIRSFMNVKHWPWMKLFFKIKPLLKSAETEKEMATMKE 860 +LAR + + ++ A+ IQ N +++ +++W W +LF K+KPLL+ E+EM ++ Sbjct: 807 YLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKED 866 Query: 861 EFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCDQLIKTKIQ 920 E QK K+ K+E + KELE+K L +EKN LQ Q+QAE E A+AEE +L K + Sbjct: 867 ELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQE 926 Query: 921 LEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENK 980 LE + E+ R E+EE+ +L A+++K+ + +L++ +++ E K++ EK E K Sbjct: 927 LEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAK 986 Query: 981 VKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDL 1040 +K L +E+ +D+ KL+KE+K L+E +L EE+K LTK K K E + +L Sbjct: 987 IKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISEL 1046 Query: 1041 EGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKI 1100 E L++E+K R +LE+ KRKLEGD E I D++ + +L +L KKE E+ +++ Sbjct: 1047 EVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARL 1106 Query: 1101 EDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAG 1160 +DE A KKI+EL+ I +L+E++++ERA+R KAEKQ+ DL ELE + LE+ Sbjct: 1107 DDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTL 1166 Query: 1161 GATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVK 1220 +T+ Q E+ KRE E +++ L+E T HEA +R+KHA +V EL EQ++ +R K Sbjct: 1167 DSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAK 1226 Query: 1221 QKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLT 1280 L+K K ++ E DLA + + +AK +E + LE Q+ EL+SK + +R +L Sbjct: 1227 ANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELN 1286 Query: 1281 AQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQ 1340 + +LQ E + L+E E +L++ + + Q+++ + L+EE + K ++ L+ Sbjct: 1287 DKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLR 1346 Query: 1341 SSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLA 1400 + + L++Q +EE E+K L+R +S N +++ + K + D E LEE KK+ Sbjct: 1347 QLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQ-DFASTVEALEEGKKRFQ 1405 Query: 1401 QRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILA 1460 + ++ + E A LEKTK RLQ E++DL++D++ + L+KKQR FD++LA Sbjct: 1406 KEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLA 1465 Query: 1461 EWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTE 1520 E K + E + ++ EAR T+ + A EE+L+ E L+R NK L+ E+ DL Sbjct: 1466 EEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVS 1525 Query: 1521 QIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDR 1580 + GK +HELEK K+ +E + E++ LEE E L+ E LR+++ + +K + +R Sbjct: 1526 SKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFER 1585 Query: 1581 KIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANR 1640 + +DE+ ++ +R R + ++ L+ E + R A KKK+EGDL ++E+Q + A + Sbjct: 1586 DLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIK 1645 Query: 1641 MAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQ 1700 EA++ R Q +KD Q L+DA S++++ E++A L+A++ +L+ L Sbjct: 1646 GREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAA 1705 Query: 1701 TERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEK 1760 ER+RK A+ E + +E + + +L + K++LE I+Q++ E+E+ ++ Sbjct: 1706 AERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDR 1765 Query: 1761 AKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQK 1820 +KA A ++ EL E+ T+ E ++ +E+ K+L+ +L E E K I Sbjct: 1766 VRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAA 1825 Query: 1821 LEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAK 1880 LEA++ +LE +VE E + A K L++ ++++KE+ Q E++RK + ++ +K A+ Sbjct: 1826 LEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNAR 1885 Query: 1881 VKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAESQVNKLRVKSR 1931 VK KRQ EEAEE+S A RKLQ EL+EA E + +VN L+ K R Sbjct: 1886 VKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLR 1936 Score = 216 bits (549), Expect = 2e-55 Identities = 189/902 (20%), Positives = 433/902 (48%), Gaps = 53/902 (5%) Query: 1083 DEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQR 1142 +E+++ KE E+ + + + + +L++K +L L+E+++AE A+AE+ R Sbjct: 858 EEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMR 917 Query: 1143 SDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRR---DLEEATLQHEATAATLR 1199 L+ + +E+ E L E + + ++ +AE +KM + DLEE + EA L+ Sbjct: 918 VRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQ 977 Query: 1200 KKHADSVAE---LGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCR 1256 + + A+ L ++I + KL KE+ ++ I DL +N+ + NL K+ Sbjct: 978 LEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKN 1037 Query: 1257 TLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQ 1316 E +SEL+ + +++++ +L + +L+ ++ +F Q+ + +A +++L + Sbjct: 1038 KHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEE 1097 Query: 1317 QIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQ 1376 +++ +L++EI KN ++ L+E + E+ ++ + ++ E+ Sbjct: 1098 ELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEA 1157 Query: 1377 WRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHV-EAVNAKCASLEKTKQRLQNEVEDLM 1435 +T+ E D + T +E + K Q + ++ + E + A +++ +Q+ VE+L Sbjct: 1158 LKTELE-DTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELT 1216 Query: 1436 LDVERTNAACAALDKKQRNFDK----------ILAEWKQKCEETHAELEASQKEARS--- 1482 +E+ A A LDK ++ +K +L + KQ+ E +LEA +E +S Sbjct: 1217 EQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCS 1276 Query: 1483 --------LGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEK 1534 L ++ K++N E L + + L ++++ L+ Q+ + + + E + Sbjct: 1277 DGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETR 1336 Query: 1535 IK-------KQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDE 1587 K +Q+E+E+ LQ L+E + ++ E I + ++L+ K ++ + A E Sbjct: 1337 QKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKL-QDFASTVE 1395 Query: 1588 EIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALR 1647 +++ K+ + +E++ + + + + + K +++ +L+++ + L++ ++ + + Sbjct: 1396 ALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEK 1455 Query: 1648 NYRNTQGILKD----TQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTER 1703 R +L + + + D+ R++ + +E+ E +A L +EE E+ ER Sbjct: 1456 KQRKFDQLLAEEKNISSKYADERDRAEAEAREK----ETKALSLARALEEALEAKEELER 1511 Query: 1704 SRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEE-KAK 1762 + K+ + E+ D + L +K+ LET + +M+ ++E++ E + E+ K + Sbjct: 1512 TNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLR 1571 Query: 1763 KAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRL-DEAEQLALKGGKKQIQKL 1821 + A+ + + Q E ++ +++ + + + L DE +Q AL K+ KL Sbjct: 1572 LEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKK--KL 1629 Query: 1822 EARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKV 1881 E +++LE + +S K EA+K LRK + ++K+ + E+ R + + + + K Sbjct: 1630 EGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKA 1689 Query: 1882 KSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAESQV--NKLRVKSREVHTKVIS 1939 KS +A+ + Q + A+ + Q +LE+ E ++A S N L+ + R + ++ Sbjct: 1690 KSL--EADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQ 1747 Query: 1940 EE 1941 E Sbjct: 1748 LE 1749 Score = 75.5 bits (184), Expect = 5e-13 Identities = 59/271 (21%), Positives = 119/271 (43%), Gaps = 8/271 (2%) Query: 1668 RSQEDLK---EQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHT 1724 R +E+++ ++L + R + E++EL Q + + +++L +E Sbjct: 856 RQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEE 915 Query: 1725 QNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAH 1784 L K++LE + +M+ +E+ + + + KK + E+L++E+ Sbjct: 916 MRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQK 975 Query: 1785 LERMKKNMEQTVKDLQLRLDEAEQLALKGGK--KQIQKLEARVRELEGEVESEQKRNAEA 1842 L+ K E +K L+ DE + + K K+ + LE R+ +L + E+++ Sbjct: 976 LQLEKVTAEAKIKKLE---DEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNL 1032 Query: 1843 VKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKF 1902 K KHE + EL + +++ K+ L+ L KL+ + Q + + Q + Sbjct: 1033 TKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQL 1092 Query: 1903 RKLQHELEEAEERADIAESQVNKLRVKSREV 1933 K + EL+ A R D +Q N K RE+ Sbjct: 1093 AKKEEELQAALARLDDEIAQKNNALKKIREL 1123 >gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo sapiens] Length = 1938 Score = 1423 bits (3683), Expect = 0.0 Identities = 779/1908 (40%), Positives = 1181/1908 (61%), Gaps = 20/1908 (1%) Query: 34 AKTSVFVAEPKESFVKGTIQSREGGKVTVK-TEGGATLTVKDDQVFPMNPPKYDKIEDMA 92 AK V+V K+ F +I+ +G +V V+ E G +TV D + MNPPK+ K+EDMA Sbjct: 32 AKRLVWVPSEKQGFEAASIKEEKGDEVVVELVENGKKVTVGKDDIQKMNPPKFSKVEDMA 91 Query: 93 MMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYKPEVVTAYRGKKRQEAP 152 +T L+E +VL+NL+ERY + +IYTYSGLFCV VNPYK LP+Y ++V Y+GKKR E P Sbjct: 92 ELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKRHEMP 151 Query: 153 PHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKEEITS 212 PHI++I+D AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY A +A + + KK+ Sbjct: 152 PHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKDT--- 208 Query: 213 GKIQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLE 272 I G LE Q++ ANP+LEAFGNAKTV+NDNSSRFGKFIRI+F TG + A+IETYLLE Sbjct: 209 -SITGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLE 267 Query: 273 KSRVVFQLKAERSYHIFYQITSNKKPELIEMLLITTNPYDYPFVSQGEISVASIDDQEEL 332 KSR + Q + ER++HIFY + + K ++ LL+ +Y F+S G + + + D E Sbjct: 268 KSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLE-GFNNYTFLSNGFVPIPAAQDDEMF 326 Query: 333 MATDSAIDILGFTNEEKVSIYKLTGAVMHYGNLKFKQKQREEQAEPDGTEVADKAAYLQS 392 T A+ I+GF+ EE++SI K+ +V+ GN+ FK+++ +QA A K +L Sbjct: 327 QETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKVCHLMG 386 Query: 393 LNSADLLKALCYPRVKVGNEYVTKGQTVEQVSNAVGALAKAVYEKMFLWMVARINQQLD- 451 +N D +++ PR+KVG + V K QT EQ AV ALAKA YE++F W++ R+N+ LD Sbjct: 387 INVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRVNKALDK 446 Query: 452 TKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEW 511 T + F+G+LDIAGFEIF+ NS EQLCIN+TNEKLQQ FNH MF+LEQEEY++EGIEW Sbjct: 447 THRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEW 506 Query: 512 TFIDFGMDLAACIELIEKPM---GIFSILEEECMFPKATDTSFKNKLYDQHLGKSANFQK 568 FIDFG+DL CIELIE+P G+ ++L+EEC FPKATD SF KL + G FQK Sbjct: 507 NFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQ-GSHPKFQK 565 Query: 569 PKVVKGKAEAHFALIHYAGVVDYNITGWLEKNKDPLNETVVGLYQKSAMKTLAQLFSGAQ 628 PK +K K E F++IHYAG VDYN + WL KN DPLN+ V L S+ K +A L+ Sbjct: 566 PKQLKDKTE--FSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLWKDVD 623 Query: 629 TAEG-----EGAGGGAKKGGKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPNE 683 G + K K F+TV L++E L KLMT LR+T P+FVRCIIPN Sbjct: 624 RIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCIIPNH 683 Query: 684 TKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQFID 743 K G ++ LVL QLRCNGVLEGIRICR+GFP+RI++ +F+QRY++L A+AIP+G F+D Sbjct: 684 EKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKG-FMD 742 Query: 744 SKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDDKLAQLITRTQARCRGFLA 803 K+A ++ ++++D Y+ G +K+FF+ G+L LEE RD K+ +I QA CRG+LA Sbjct: 743 GKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRGYLA 802 Query: 804 RVEYQRMVERREAIFCIQYNIRSFMNVKHWPWMKLFFKIKPLLKSAETEKEMATMKEEFQ 863 R + + ++ A+ IQ N +++ +++W W +LF K+KPLL+ E+EM ++E Q Sbjct: 803 RKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKEDELQ 862 Query: 864 KIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCDQLIKTKIQLEA 923 K K+ K+E + KELE+K L +EKN LQ Q+QAE E A+AEE +L K +LE Sbjct: 863 KTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEE 922 Query: 924 KIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKN 983 + E+ R E+EE+ +L A+++K+ + +L++ +++ E K++ EK E K+K Sbjct: 923 ILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKK 982 Query: 984 LTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGS 1043 L +E+ +D+ KL+KE+K L+E +L EE+K LTK K K E + +LE Sbjct: 983 LEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVR 1042 Query: 1044 LEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDE 1103 L++E+K R +LE+ KRKLEGD E I D++ + +L +L KKE E+ ++++DE Sbjct: 1043 LKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDE 1102 Query: 1104 QALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGAT 1163 A KKI+EL+ I +L+E++++ERA+R KAEKQ+ DL ELE + LE+ +T Sbjct: 1103 IAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDST 1162 Query: 1164 SAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKL 1223 + Q E+ KRE E +++ L+E T HEA +R+KHA +V EL EQ++ +R K L Sbjct: 1163 ATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANL 1222 Query: 1224 EKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQR 1283 +K K ++ E DLA + + +AK +E + LE Q+ EL+SK + +R +L + Sbjct: 1223 DKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKV 1282 Query: 1284 GRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSR 1343 +LQ E + L+E E +L++ + + Q+++ + L+EE + K ++ L+ Sbjct: 1283 HKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLE 1342 Query: 1344 HDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRL 1403 + + L++Q +EE E+K L+R +S N +++ + K + D E LEE KK+ + + Sbjct: 1343 EERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQ-DFASTVEALEEGKKRFQKEI 1401 Query: 1404 QAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWK 1463 + + E A LEKTK RLQ E++DL++D++ + L+KKQR FD++LAE K Sbjct: 1402 ENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEK 1461 Query: 1464 QKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIA 1523 + E + ++ EAR T+ + A EE+L+ E L+R NK L+ E+ DL Sbjct: 1462 NISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKD 1521 Query: 1524 EGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIA 1583 + GK +HELEK K+ +E + E++ LEE E L+ E LR+++ + +K + +R + Sbjct: 1522 DVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQ 1581 Query: 1584 EKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAA 1643 +DE+ ++ +R R + ++ L+ E + R A KKK+EGDL ++E+Q + A + Sbjct: 1582 ARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGRE 1641 Query: 1644 EALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTER 1703 EA++ R Q +KD Q L+DA S++++ E++A L+A++ +L+ L ER Sbjct: 1642 EAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAER 1701 Query: 1704 SRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKK 1763 +RK A+ E + +E + + +L + K++LE I+Q++ E+E+ ++ +K Sbjct: 1702 ARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRK 1761 Query: 1764 AITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEA 1823 A A ++ EL E+ T+ E ++ +E+ K+L+ +L E E K I LEA Sbjct: 1762 ATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEA 1821 Query: 1824 RVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKS 1883 ++ +LE +VE E + A K L++ ++++KE+ Q E++RK + ++ +K A+VK Sbjct: 1822 KIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQ 1881 Query: 1884 YKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAESQVNKLRVKSR 1931 KRQ EEAEE+S A RKLQ EL+EA E + +VN L+ K R Sbjct: 1882 LKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLR 1929 Score = 216 bits (549), Expect = 2e-55 Identities = 189/902 (20%), Positives = 433/902 (48%), Gaps = 53/902 (5%) Query: 1083 DEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQR 1142 +E+++ KE E+ + + + + +L++K +L L+E+++AE A+AE+ R Sbjct: 851 EEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMR 910 Query: 1143 SDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRR---DLEEATLQHEATAATLR 1199 L+ + +E+ E L E + + ++ +AE +KM + DLEE + EA L+ Sbjct: 911 VRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQ 970 Query: 1200 KKHADSVAE---LGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCR 1256 + + A+ L ++I + KL KE+ ++ I DL +N+ + NL K+ Sbjct: 971 LEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKN 1030 Query: 1257 TLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQ 1316 E +SEL+ + +++++ +L + +L+ ++ +F Q+ + +A +++L + Sbjct: 1031 KHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEE 1090 Query: 1317 QIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQ 1376 +++ +L++EI KN ++ L+E + E+ ++ + ++ E+ Sbjct: 1091 ELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEA 1150 Query: 1377 WRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHV-EAVNAKCASLEKTKQRLQNEVEDLM 1435 +T+ E D + T +E + K Q + ++ + E + A +++ +Q+ VE+L Sbjct: 1151 LKTELE-DTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELT 1209 Query: 1436 LDVERTNAACAALDKKQRNFDK----------ILAEWKQKCEETHAELEASQKEARS--- 1482 +E+ A A LDK ++ +K +L + KQ+ E +LEA +E +S Sbjct: 1210 EQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCS 1269 Query: 1483 --------LGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEK 1534 L ++ K++N E L + + L ++++ L+ Q+ + + + E + Sbjct: 1270 DGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETR 1329 Query: 1535 IK-------KQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDE 1587 K +Q+E+E+ LQ L+E + ++ E I + ++L+ K ++ + A E Sbjct: 1330 QKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKL-QDFASTVE 1388 Query: 1588 EIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALR 1647 +++ K+ + +E++ + + + + + K +++ +L+++ + L++ ++ + + Sbjct: 1389 ALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEK 1448 Query: 1648 NYRNTQGILKD----TQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTER 1703 R +L + + + D+ R++ + +E+ E +A L +EE E+ ER Sbjct: 1449 KQRKFDQLLAEEKNISSKYADERDRAEAEAREK----ETKALSLARALEEALEAKEELER 1504 Query: 1704 SRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEE-KAK 1762 + K+ + E+ D + L +K+ LET + +M+ ++E++ E + E+ K + Sbjct: 1505 TNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLR 1564 Query: 1763 KAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRL-DEAEQLALKGGKKQIQKL 1821 + A+ + + Q E ++ +++ + + + L DE +Q AL K+ KL Sbjct: 1565 LEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKK--KL 1622 Query: 1822 EARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKV 1881 E +++LE + +S K EA+K LRK + ++K+ + E+ R + + + + K Sbjct: 1623 EGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKA 1682 Query: 1882 KSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAESQV--NKLRVKSREVHTKVIS 1939 KS +A+ + Q + A+ + Q +LE+ E ++A S N L+ + R + ++ Sbjct: 1683 KSL--EADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQ 1740 Query: 1940 EE 1941 E Sbjct: 1741 LE 1742 Score = 75.5 bits (184), Expect = 5e-13 Identities = 59/271 (21%), Positives = 119/271 (43%), Gaps = 8/271 (2%) Query: 1668 RSQEDLK---EQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHT 1724 R +E+++ ++L + R + E++EL Q + + +++L +E Sbjct: 849 RQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEE 908 Query: 1725 QNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAH 1784 L K++LE + +M+ +E+ + + + KK + E+L++E+ Sbjct: 909 MRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQK 968 Query: 1785 LERMKKNMEQTVKDLQLRLDEAEQLALKGGK--KQIQKLEARVRELEGEVESEQKRNAEA 1842 L+ K E +K L+ DE + + K K+ + LE R+ +L + E+++ Sbjct: 969 LQLEKVTAEAKIKKLE---DEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNL 1025 Query: 1843 VKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKF 1902 K KHE + EL + +++ K+ L+ L KL+ + Q + + Q + Sbjct: 1026 TKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQL 1085 Query: 1903 RKLQHELEEAEERADIAESQVNKLRVKSREV 1933 K + EL+ A R D +Q N K RE+ Sbjct: 1086 AKKEEELQAALARLDDEIAQKNNALKKIREL 1116 >gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] Length = 1976 Score = 1413 bits (3657), Expect = 0.0 Identities = 774/1918 (40%), Positives = 1191/1918 (62%), Gaps = 26/1918 (1%) Query: 27 AQNRPFDAKTSVFVAEPKESFVKGTIQSREGGKVTVK-TEGGATLTVKDDQVFPMNPPKY 85 A + AK V++ + F +I+ G +V V+ E G V D + MNPPK+ Sbjct: 25 ATQADWTAKKLVWIPSERHGFEAASIKEERGDEVMVELAENGKKAMVNKDDIQKMNPPKF 84 Query: 86 DKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYKPEVVTAYRG 145 K+EDMA +T L+E +VL+NLK+RY + +IYTYSGLFCV +NPYK LP+Y ++ YRG Sbjct: 85 SKVEDMAELTCLNEASVLHNLKDRYYSGLIYTYSGLFCVVINPYKNLPIYSENIIEMYRG 144 Query: 146 KKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEK 205 KKR E PPHI++IS++AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY A +A + + Sbjct: 145 KKRHEMPPHIYAISESAYRCMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSHKG 204 Query: 206 KKEEITSGKIQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASAD 265 +K+ I G LE Q++ ANP+LE+FGNAKTV+NDNSSRFGKFIRI+F TG + A+ Sbjct: 205 RKDH----NIPGELERQLLQANPILESFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGAN 260 Query: 266 IETYLLEKSRVVFQLKAERSYHIFYQITSNKKPELIEMLLITTNPYDYPFVSQGEISVAS 325 IETYLLEKSR V Q K ER++HIFYQ+ S L LL+ +Y F+S G I + Sbjct: 261 IETYLLEKSRAVRQAKDERTFHIFYQLLSGAGEHLKSDLLLE-GFNNYRFLSNGYIPIPG 319 Query: 326 IDDQEELMATDSAIDILGFTNEEKVSIYKLTGAVMHYGNLKFKQKQREEQAEPDGTEVAD 385 D++ T A+ I+GF++EE +S+ K+ +V+ +GN+ FK+++ +QA VA Sbjct: 320 QQDKDNFQETMEAMHIMGFSHEEILSMLKVVSSVLQFGNISFKKERNTDQASMPENTVAQ 379 Query: 386 KAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTVEQVSNAVGALAKAVYEKMFLWMVAR 445 K +L +N + +A+ PR+KVG +YV K QT EQ AV ALAKA YE++F W+V R Sbjct: 380 KLCHLLGMNVMEFTRAILTPRIKVGRDYVQKAQTKEQADFAVEALAKATYERLFRWLVHR 439 Query: 446 INQQLD-TKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEY 504 IN+ LD TK+ FIG+LDIAGFEIF+ NS EQLCIN+TNEKLQQ FNH MF+LEQEEY Sbjct: 440 INKALDRTKRQGASFIGILDIAGFEIFELNSFEQLCINYTNEKLQQLFNHTMFILEQEEY 499 Query: 505 KKEGIEWTFIDFGMDLAACIELIEKPM---GIFSILEEECMFPKATDTSFKNKLYDQHLG 561 ++EGIEW FIDFG+DL CI+LIE+P G+ ++L+EEC FPKATD +F KL Q G Sbjct: 500 QREGIEWNFIDFGLDLQPCIDLIERPANPPGVLALLDEECWFPKATDKTFVEKLV-QEQG 558 Query: 562 KSANFQKPKVVKGKAEAHFALIHYAGVVDYNITGWLEKNKDPLNETVVGLYQKSAMKTLA 621 + FQKP+ +K KA+ F +IHYAG VDY WL KN DPLN+ V L +S+ + +A Sbjct: 559 SHSKFQKPRQLKDKAD--FCIIHYAGKVDYKADEWLMKNMDPLNDNVATLLHQSSDRFVA 616 Query: 622 QLFSGAQTAEG--------EGAGGGAKKGGKKKGSSFQTVSALFRENLNKLMTNLRSTHP 673 +L+ G E A G A K KKG F+TV L++E+L KLM LR+T+P Sbjct: 617 ELWKDVDRIVGLDQVTGMTETAFGSAYK--TKKGM-FRTVGQLYKESLTKLMATLRNTNP 673 Query: 674 HFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNA 733 +FVRCIIPN K G ++ LVL QLRCNGVLEGIRICR+GFP+RI++ +F+QRY++L Sbjct: 674 NFVRCIIPNHEKRAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILTP 733 Query: 734 SAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDDKLAQLITR 793 +AIP+G F+D K+A E+++ ++++D Y+ G +K+FF+AG+L LEE RD K+ +I Sbjct: 734 NAIPKG-FMDGKQACERMIRALELDPNLYRIGQSKIFFRAGVLAHLEEERDLKITDIIIF 792 Query: 794 TQARCRGFLARVEYQRMVERREAIFCIQYNIRSFMNVKHWPWMKLFFKIKPLLKSAETEK 853 QA CRG+LAR + + ++ A+ +Q N +++ ++HW W ++F K+KPLL+ E+ Sbjct: 793 FQAVCRGYLARKAFAKKQQQLSALKVLQRNCAAYLKLRHWQWWRVFTKVKPLLQVTRQEE 852 Query: 854 EMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCDQ 913 E+ EE K+K++ K E + +E+E K LL+EKN L Q+QAE E A+AEE + Sbjct: 853 ELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMRAR 912 Query: 914 LIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKE 973 L K +LE + ++ R E+EEE N L +K+K++ +L++ +D+ E K++ E Sbjct: 913 LAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLE 972 Query: 974 KHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKL 1033 K E K+K + EE+ L++ +K KEKK +++ + L EE+K L K + K Sbjct: 973 KVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQ 1032 Query: 1034 EQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEI 1093 E + DLE L++E+K R +LE+AKRKL+G+ Q+ I +++ + +L +L KKE E+ Sbjct: 1033 EVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEEL 1092 Query: 1094 SNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEIS 1153 ++ +DE K ++ELQA+I EL+E+ E+E+ASR KAEKQ+ DLS ELE + Sbjct: 1093 QGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALK 1152 Query: 1154 ERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQI 1213 LE+ T+AQ E+ KRE E ++++ LEE T HEA +R++HA ++ EL EQ+ Sbjct: 1153 TELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQL 1212 Query: 1214 DNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQ 1273 + +R K LEK K ++ + +LA V+ + + K E + L+ Q+ EL +K E Sbjct: 1213 EQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGD 1272 Query: 1274 RLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKN 1333 RL +L + +LQ E S L+E E + ++ + Q+++ + L+EE + K Sbjct: 1273 RLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKL 1332 Query: 1334 ALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELE 1393 L+ ++ + + L+EQ EEE+E++ L++ + +++A + K + D + E LE Sbjct: 1333 NLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDD-LGTIESLE 1391 Query: 1394 EAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQR 1453 EAKKKL + +A + +E LEKTK RLQ E++DL +D++ + L+KKQ+ Sbjct: 1392 EAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQK 1451 Query: 1454 NFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQ 1513 FD++LAE K E + ++ EAR T+ + A EE+L+ E +R+NK L+ Sbjct: 1452 KFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRA 1511 Query: 1514 EISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQ 1573 ++ DL + GK +HELEK K+ +EQ+ E++ LEE E L+ E LR+++ + Sbjct: 1512 DMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQA 1571 Query: 1574 VKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEI 1633 +K++ +R + +DE+ ++ KR I+ V +++ L+ E + R A+ KKKME DL ++E Sbjct: 1572 MKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEA 1631 Query: 1634 QLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEE 1693 Q+ AN+ E ++ R Q +KD Q L++A S++++ Q E++ L+AEI + Sbjct: 1632 QIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQ 1691 Query: 1694 LRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQE 1753 L+ L +ER+R+ AEQE + ++ + + ++L++ K++LE I+Q++ E+E+ Sbjct: 1692 LQEELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSN 1751 Query: 1754 ARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKG 1813 ++ +K + EL E+ + + ++ +E+ K+L+ +L E E Sbjct: 1752 MELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSK 1811 Query: 1814 GKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDL 1873 K I LEA++ +LE ++E E K A A K +R+ E+++KE+ Q E++R++ + ++ Sbjct: 1812 FKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQ 1871 Query: 1874 VDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAESQVNKLRVKSR 1931 ++K A++K KRQ EEAEE++ A RKLQ EL++A E + +V+ L+ + R Sbjct: 1872 MEKANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEANEGLSREVSTLKNRLR 1929 Score = 254 bits (648), Expect = 7e-67 Identities = 224/994 (22%), Positives = 464/994 (46%), Gaps = 125/994 (12%) Query: 850 ETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTL-------LKEKNDLQLQVQAEAE 902 + E+++ + QK++ E +EAK K++EE+++ L +KEK ++ ++ + Sbjct: 954 DLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSS 1013 Query: 903 GLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLE-------DECSE 955 LA+ EE+ L K + + E I ++ ER + EE+ EL KRKL+ D+ +E Sbjct: 1014 QLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAE 1073 Query: 956 LKKDIDDLELTLAKVEKE--------------KHATENKVKNLTEEMAGLDETIAK---- 997 L+ ID+L+L LAK E+E K+ V+ L ++A L E Sbjct: 1074 LQAQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKAS 1133 Query: 998 ----------LTKEKKALQEAHQQTLDDLQAEED----KVNTLTKAKIKLEQQ------- 1036 L++E +AL+ + TLD A+++ + + + K LE++ Sbjct: 1134 RNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQ 1193 Query: 1037 -----------VDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEK 1085 +++L LEQ K+ + +LE+ K+ LE D K + ++ K + + K Sbjct: 1194 IQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHK 1253 Query: 1086 LKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDL 1145 KK + ++ L +K+ + L ++L +K +LQ ++ + +E K K + L Sbjct: 1254 RKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASL 1313 Query: 1146 SRELEEISERLEEAG------GATSAQIEMNK----KREAEFQKMRRDLEEATLQHEATA 1195 +L++ E L+E + Q+E K +++ E ++ R++LE+ L ++ Sbjct: 1314 ESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQL 1373 Query: 1196 ATLRKKHADSVAE-----------------LGEQIDNLQRVKQKLEKEKSEMKMEIDDLA 1238 A +KK D + L ++++ KLEK K+ ++ E+DDL Sbjct: 1374 ADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLT 1433 Query: 1239 SNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLD 1298 +++ + NLEK + + L+E KS + A+ +T++ +R L+ Sbjct: 1434 VDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALE 1493 Query: 1299 EKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALA---HALQSSRH----DCDLLRE 1351 E K+ F +Q ++L+ +E+ + +K+ + H L+ S+ + +R Sbjct: 1494 EA-------LEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRT 1546 Query: 1352 QYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVE 1411 Q EE ++ + A + + + ++E D R E+ EE K+ L ++++ E +E Sbjct: 1547 QLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELE 1606 Query: 1412 AVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEETHA 1471 + A +K++++ +++DL +E N A + K+ R + +++++ EE A Sbjct: 1607 DERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARA 1666 Query: 1472 -------ELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAE 1524 + + S+K+ +SL E+ +++ ++L + +R ++ +QE +L ++I Sbjct: 1667 SRDEIFAQSKESEKKLKSLEAEILQLQ-------EELASSERARRHAEQERDELADEITN 1719 Query: 1525 GGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEV--DRKI 1582 L K+++E +L+ LEE ++++E + + L+++ + +E+ +R Sbjct: 1720 SASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSA 1779 Query: 1583 AEK-DEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRM 1641 A+K D QL+R + + +Q L+ ++S+ A +E + ++E QL + Sbjct: 1780 AQKSDNARQQLERQNKELKAKLQE-LEGAVKSKFKATI--SALEAKIGQLEEQLEQEAKE 1836 Query: 1642 AAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQT 1701 A A + R T+ LK+ + ++D R + KEQ+ R L+ ++EE + Sbjct: 1837 RAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRA 1896 Query: 1702 ERSRKIAEQELLDASERVQLLHTQNTSLINTKKK 1735 SR+ ++EL DA+E + L + ++L N ++ Sbjct: 1897 NASRRKLQRELDDATEANEGLSREVSTLKNRLRR 1930 Score = 195 bits (496), Expect = 3e-49 Identities = 203/912 (22%), Positives = 405/912 (44%), Gaps = 113/912 (12%) Query: 1076 ENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASR 1135 E E Q DE+L K + Q+K+E E ++++K ++L L E+++AE Sbjct: 851 EEELQAKDEELLK----VKEKQTKVEGELE---EMERKHQQLLEEKNILAEQLQAETELF 903 Query: 1136 AKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATA 1195 A+AE+ R+ L+ + +E+ E L + + E N+ + E +KM+ +++ Sbjct: 904 AEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQD--------- 954 Query: 1196 ATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMC 1255 L EQ+D + +QKL+ EK + +I + + + K Sbjct: 955 -------------LEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEK 1001 Query: 1256 RTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFT 1315 + +ED+++E S+ E++ +L R + + + +L ++E +L + K+ Sbjct: 1002 KLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLD 1061 Query: 1316 QQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVA 1375 + +L+ Q+ E LQ+ D L+ Q +++E ELQ AL++ + E Sbjct: 1062 GETTDLQDQIAE-----------LQAQ---IDELKLQLAKKEE---ELQGALARGDDE-- 1102 Query: 1376 QWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLM 1435 T ++ +A++ EL+ +L +E E+ A EK K+ L E+E L Sbjct: 1103 ---TLHKNNALKVVRELQAQIAEL-------QEDFESEKASRNKAEKQKRDLSEELEALK 1152 Query: 1436 LDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYE 1495 ++E T AA + + ++ +AE K+ EE EA ++ R + A E Sbjct: 1153 TELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQ------RHATALE 1206 Query: 1496 ESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEA 1555 E +QLE KR NL++ L E + L+++K + E ++ +L A ++E A Sbjct: 1207 ELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHA 1266 Query: 1556 SLEHEEGKILRIQL--ELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRS 1613 + EG LR++L + +++++E+D ++ EE ++ + S++S L Sbjct: 1267 KVS--EGDRLRVELAEKASKLQNELDN-VSTLLEEAEKKGIKFAKDAASLESQLQDTQEL 1323 Query: 1614 RNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNT-------QGILKDTQIHLDDA 1666 + R K + + ++E + N E +N Q L DT+ +DD Sbjct: 1324 LQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDD 1383 Query: 1667 LRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQN 1726 L + E L+E + + A L +EE ++ E+++ +QEL D + + Sbjct: 1384 LGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVA 1443 Query: 1727 TSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLE 1786 ++L +KK + +++ + +E AE +A++ T A +A L++ + E Sbjct: 1444 SNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFE 1503 Query: 1787 RMKKNMEQTVKDLQLRLDEAE------QLALKGGKKQIQKLEARVRELEGEVESEQKR-- 1838 R K + ++DL D+ + + + ++Q++++ ++ ELE E+++ + Sbjct: 1504 RQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKL 1563 Query: 1839 ----NAEAVKGLRKHE----------------RRVKELTYQTEEDRKNILRLQDLVDKLQ 1878 N +A+K + + ++V+EL + E++RK K++ Sbjct: 1564 RLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKME 1623 Query: 1879 AKVKSYKRQAEEAEEQSNTNLAKFRKLQ-------HELEEAEERAD--IAESQVNKLRVK 1929 +K + Q E A + + + + RKLQ ELEEA D A+S+ ++ ++K Sbjct: 1624 IDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLK 1683 Query: 1930 SREVHTKVISEE 1941 S E + EE Sbjct: 1684 SLEAEILQLQEE 1695 Score = 175 bits (444), Expect = 3e-43 Identities = 167/748 (22%), Positives = 351/748 (46%), Gaps = 64/748 (8%) Query: 853 KEMATMKEEFQKIKDELAKSEAKRKELEEKM--------------VTLLKEKNDLQLQVQ 898 KE+A + Q++K A+SE KRK+L+ ++ V L ++ + LQ ++ Sbjct: 1234 KELACEVKVLQQVK---AESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELD 1290 Query: 899 AEAEGLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKK 958 + L +AE++ + K LE+++++ E ++E L+++ R+LE+E + L++ Sbjct: 1291 NVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQE 1350 Query: 959 DIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKAL---QEAHQQTLDD 1015 ++ E +EK+ A ++++ + +++ TI L + KK L EA Q L++ Sbjct: 1351 QQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEE 1410 Query: 1016 LQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDI 1075 DK L K K +L+Q++DDL L+ ++++ +LE+ ++K D LA+E + Sbjct: 1411 KALAYDK---LEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKF--DQLLAEEKSISA 1465 Query: 1076 E--NEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERA 1133 E+ + + + ++KE + +L +E+ + +++ K+L+A +E+L + Sbjct: 1466 RYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGK 1525 Query: 1134 SRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMR----RDLEEATL 1189 + + EK + L +++EE+ +LEE A + + E Q M+ RDL+ Sbjct: 1526 NVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDE 1585 Query: 1190 QHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKG 1249 Q+E L K+ V EL ++++ ++ + K +M++++ DL + +E +KA+ Sbjct: 1586 QNEEKKRLLIKQ----VRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARD 1641 Query: 1250 NLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLS- 1308 + K R L+ Q+ ++ QR + + A R + +S E ++L EA + QL Sbjct: 1642 EVIKQLRKLQAQM-------KDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQE 1694 Query: 1309 ------RGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAE 1362 R ++ Q+ +EL ++ K+AL + L E+ EEEQ + Sbjct: 1695 ELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMEL 1754 Query: 1363 LQRALSKANTEVAQWRTKY--ETDAIQRTE----ELEEAKKKLAQRLQAAEEHVEA-VNA 1415 L K +V + E A Q+++ +LE K+L +LQ E V++ A Sbjct: 1755 LNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSKFKA 1814 Query: 1416 KCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNF-------DKILAEWKQKCEE 1468 ++LE +L+ ++E + N +KK + + ++K++ E+ Sbjct: 1815 TISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEK 1874 Query: 1469 THAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGK- 1527 +A ++ +++ E + + + +L+ N+ L +E+S L ++ GG Sbjct: 1875 ANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEANEGLSREVSTLKNRLRRGGPI 1934 Query: 1528 RIHELEKIKKQVEQEKCELQAALEEAEA 1555 ++Q+ E L+ + ++ E+ Sbjct: 1935 SFSSSRSGRRQLHLEGASLELSDDDTES 1962 >gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] Length = 1960 Score = 1410 bits (3651), Expect = 0.0 Identities = 771/1909 (40%), Positives = 1179/1909 (61%), Gaps = 25/1909 (1%) Query: 34 AKTSVFVAEPKESFVKGTIQSREGGKVTVK-TEGGATLTVKDDQVFPMNPPKYDKIEDMA 92 AK V+V K F +++ G + V+ E G + V D + MNPPK+ K+EDMA Sbjct: 28 AKKLVWVPSDKSGFEPASLKEEVGEEAIVELVENGKKVKVNKDDIQKMNPPKFSKVEDMA 87 Query: 93 MMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYKPEVVTAYRGKKRQEAP 152 +T L+E +VL+NLKERY + +IYTYSGLFCV +NPYK LP+Y E+V Y+GKKR E P Sbjct: 88 ELTCLNEASVLHNLKERYYSGLIYTYSGLFCVVINPYKNLPIYSEEIVEMYKGKKRHEMP 147 Query: 153 PHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKEEITS 212 PHI++I+D AY+ M+ DRE+QSIL TGESGAGKT NTK+VIQY A +A + + KK+ Sbjct: 148 PHIYAITDTAYRSMMQDREDQSILCTGESGAGKTENTKKVIQYLAYVASSHKSKKD---- 203 Query: 213 GKIQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLE 272 QG LE Q++ ANP+LEAFGNAKTV+NDNSSRFGKFIRI+F G + A+IETYLLE Sbjct: 204 ---QGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVNGYIVGANIETYLLE 260 Query: 273 KSRVVFQLKAERSYHIFYQITSNKKPELIEMLLITTNPYD-YPFVSQGEISVASIDDQEE 331 KSR + Q K ER++HIFY + S L LL+ PY+ Y F+S G +++ D++ Sbjct: 261 KSRAIRQAKEERTFHIFYYLLSGAGEHLKTDLLL--EPYNKYRFLSNGHVTIPGQQDKDM 318 Query: 332 LMATDSAIDILGFTNEEKVSIYKLTGAVMHYGNLKFKQKQREEQAEPDGTEVADKAAYLQ 391 T A+ I+G EE++ + ++ V+ GN+ FK+++ +QA A K ++L Sbjct: 319 FQETMEAMRIMGIPEEEQMGLLRVISGVLQLGNIVFKKERNTDQASMPDNTAAQKVSHLL 378 Query: 392 SLNSADLLKALCYPRVKVGNEYVTKGQTVEQVSNAVGALAKAVYEKMFLWMVARINQQLD 451 +N D + + PR+KVG +YV K QT EQ A+ ALAKA YE+MF W+V RIN+ LD Sbjct: 379 GINVTDFTRGILTPRIKVGRDYVQKAQTKEQADFAIEALAKATYERMFRWLVLRINKALD 438 Query: 452 -TKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIE 510 TK+ FIG+LDIAGFEIFD NS EQLCIN+TNEKLQQ FNH MF+LEQEEY++EGIE Sbjct: 439 KTKRQGASFIGILDIAGFEIFDLNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIE 498 Query: 511 WTFIDFGMDLAACIELIEKPMG---IFSILEEECMFPKATDTSFKNKLYDQHLGKSANFQ 567 W FIDFG+DL CI+LIEKP G I ++L+EEC FPKATD SF K+ Q G FQ Sbjct: 499 WNFIDFGLDLQPCIDLIEKPAGPPGILALLDEECWFPKATDKSFVEKVM-QEQGTHPKFQ 557 Query: 568 KPKVVKGKAEAHFALIHYAGVVDYNITGWLEKNKDPLNETVVGLYQKSAMKTLAQLFSGA 627 KPK +K KA+ F +IHYAG VDY WL KN DPLN+ + L +S+ K +++L+ Sbjct: 558 KPKQLKDKAD--FCIIHYAGKVDYKADEWLMKNMDPLNDNIATLLHQSSDKFVSELWKDV 615 Query: 628 QTAEGEGAGGGAKKGG-----KKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPN 682 G G + K + F+TV L++E L KLM LR+T+P+FVRCIIPN Sbjct: 616 DRIIGLDQVAGMSETALPGAFKTRKGMFRTVGQLYKEQLAKLMATLRNTNPNFVRCIIPN 675 Query: 683 ETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQFI 742 K G ++ LVL QLRCNGVLEGIRICR+GFP+R+++ +F+QRY++L ++IP+G F+ Sbjct: 676 HEKKAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRVVFQEFRQRYEILTPNSIPKG-FM 734 Query: 743 DSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDDKLAQLITRTQARCRGFL 802 D K+A ++ ++++D Y+ G +KVFF+AG+L LEE RD K+ +I QA CRG+L Sbjct: 735 DGKQACVLMIKALELDSNLYRIGQSKVFFRAGVLAHLEEERDLKITDVIIGFQACCRGYL 794 Query: 803 ARVEYQRMVERREAIFCIQYNIRSFMNVKHWPWMKLFFKIKPLLKSAETEKEMATMKEEF 862 AR + + ++ A+ +Q N +++ +++W W +LF K+KPLL+ + E+EM +EE Sbjct: 795 ARKAFAKRQQQLTAMKVLQRNCAAYLKLRNWQWWRLFTKVKPLLQVSRQEEEMMAKEEEL 854 Query: 863 QKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCDQLIKTKIQLE 922 K++++ +E + E+E L+ EK LQ Q+QAE E A+AEE +L K +LE Sbjct: 855 VKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEELRARLTAKKQELE 914 Query: 923 AKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVK 982 ++ R E+EEE L A+K+K++ EL++ +++ E K++ EK TE K+K Sbjct: 915 EICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLK 974 Query: 983 NLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEG 1042 L EE L++ KL KEKK L++ + +L EE+K +L K K K E + DLE Sbjct: 975 KLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEE 1034 Query: 1043 SLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIED 1102 L +E+K R +LE+ +RKLEGD + I +++ + +L +L KKE E+ +++E+ Sbjct: 1035 RLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEE 1094 Query: 1103 EQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGA 1162 E A KKI+EL+++I EL+E++E+ERASR KAEKQ+ DL ELE + LE+ + Sbjct: 1095 EAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDS 1154 Query: 1163 TSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQK 1222 T+AQ E+ KRE E +++ LEE HEA +R+KH+ +V EL EQ++ +RVK Sbjct: 1155 TAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKAN 1214 Query: 1223 LEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQ 1282 LEK K ++ E +LA+ V+ + + KG+ E + +E QL EL+ K E +R+ +L + Sbjct: 1215 LEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADK 1274 Query: 1283 RGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSS 1342 +LQ E + L + ++ S+L++ A Q+++ + L+EE + K +L+ L+ Sbjct: 1275 VTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQV 1334 Query: 1343 RHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQR 1402 + + REQ EEE+E+K L++ ++ + +VA + K E D++ E EE K+KL + Sbjct: 1335 EDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKME-DSVGCLETAEEVKRKLQKD 1393 Query: 1403 LQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEW 1462 L+ + E A LEKTK RLQ E++DL++D++ + L+KKQ+ FD++LAE Sbjct: 1394 LEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEE 1453 Query: 1463 KQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQI 1522 K + E + ++ EAR T+ + A EE+++Q L+R NK + E+ DL Sbjct: 1454 KTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSK 1513 Query: 1523 AEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKI 1582 + GK +HELEK K+ +EQ+ E++ LEE E L+ E LR+++ L +K++ +R + Sbjct: 1514 DDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDL 1573 Query: 1583 AEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMA 1642 +DE+ ++ K+ +R V M++ L+ E + R+ A+ +KK+E DL ++E ++ AN+ Sbjct: 1574 QGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNR 1633 Query: 1643 AEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTE 1702 EA++ R Q +KD LDD S+E++ Q E++ ++AE+ +L+ L E Sbjct: 1634 DEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAE 1693 Query: 1703 RSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAK 1762 R+++ A+QE + ++ + + + K++LE I+Q++ E+E+ ++ K Sbjct: 1694 RAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDRLK 1753 Query: 1763 KAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLE 1822 KA + +L E+ + E ++ +E+ K+L+++L E E K I LE Sbjct: 1754 KANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKASITALE 1813 Query: 1823 ARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVK 1882 A++ +LE ++++E K A K +R+ E+++K++ Q +++R+N + +D DK ++K Sbjct: 1814 AKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLK 1873 Query: 1883 SYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAESQVNKLRVKSR 1931 KRQ EEAEE++ A RKLQ ELE+A E AD +V+ L+ K R Sbjct: 1874 QLKRQLEEAEEEAQRANASRRKLQRELEDATETADAMNREVSSLKNKLR 1922 Score = 264 bits (675), Expect = 6e-70 Identities = 234/986 (23%), Positives = 457/986 (46%), Gaps = 109/986 (11%) Query: 850 ETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTL-------LKEKNDLQLQVQAEAE 902 E E+++ + QK++ E +EAK K+LEE+ + L KEK L+ ++ Sbjct: 947 ELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTT 1006 Query: 903 GLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLE-------DECSE 955 L + EE+ L K K + EA I ++ ER EE+ EL +RKLE D+ +E Sbjct: 1007 NLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAE 1066 Query: 956 LKKDIDDLELTLAKVEKE--------------KHATENKVKNLTEEMAGLDETIAK---- 997 L+ I +L++ LAK E+E K+ K++ L +++ L E + Sbjct: 1067 LQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERAS 1126 Query: 998 ----------LTKEKKALQEAHQQTLDDLQAE-------EDKVNTLTKA----------- 1029 L +E +AL+ + TLD A+ E +VN L K Sbjct: 1127 RNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQ 1186 Query: 1030 ----KIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEK 1085 + K Q V++L LEQ K+++ +LE+AK+ LE + + + K + K Sbjct: 1187 IQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHK 1246 Query: 1086 LKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDL 1145 KK E ++ LQ K + + + +L K+ +LQ ++ + + + +K K S L Sbjct: 1247 RKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSAL 1306 Query: 1146 SRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEE------------ATLQHEA 1193 +L++ E L+E + K+ E E R LEE ATL A Sbjct: 1307 ESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLH--A 1364 Query: 1194 TAATLRKKHADSVA--ELGEQID-----NLQRVKQ----------KLEKEKSEMKMEIDD 1236 A ++KK DSV E E++ +L+ + Q KLEK K+ ++ E+DD Sbjct: 1365 QVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDD 1424 Query: 1237 LASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQ 1296 L +++ ++ NLEK + + L+E K+ + + A+ +T++ +R Sbjct: 1425 LLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARA 1484 Query: 1297 LDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEE 1356 L+E ++L R + F ++E+L ++ K+ + L + ++ + ++ Q EE Sbjct: 1485 LEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEEL 1544 Query: 1357 QESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAK 1416 ++ + A + + + ++E D R E+ EE KK+L ++++ E +E + Sbjct: 1545 EDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQ 1604 Query: 1417 CASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEAS 1476 + +++L+ +++DL ++ N K+ R + + ++ ++T A E Sbjct: 1605 RSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEI 1664 Query: 1477 QKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEG-GKRIHELEKI 1535 +A+ +L ++ + ++L +R + QQE +L ++IA GK LE+ Sbjct: 1665 LAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEE- 1723 Query: 1536 KKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEV--DRKIAEKDEEI-DQL 1592 K+++E +L+ LEE + + E ++ + L+++Q+ +++ +R A+K+E QL Sbjct: 1724 KRRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQL 1783 Query: 1593 KRNHIRI---VESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNY 1649 +R + + ++ M+ T+ ++ ++ A+ K + ++E QL++ + A + Sbjct: 1784 ERQNKELKVKLQEMEGTVKSKYKASITALEAK------IAQLEEQLDNETKERQAACKQV 1837 Query: 1650 RNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAE 1709 R T+ LKD + +DD R+ E K+Q R L+ ++EE ++ SR+ + Sbjct: 1838 RRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQ 1897 Query: 1710 QELLDASERVQLLHTQNTSLINTKKK 1735 +EL DA+E ++ + +SL N ++ Sbjct: 1898 RELEDATETADAMNREVSSLKNKLRR 1923 Score = 236 bits (602), Expect = 2e-61 Identities = 202/976 (20%), Positives = 456/976 (46%), Gaps = 82/976 (8%) Query: 999 TKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAK 1058 TK K LQ + Q+ +++ A+E+++ + + ++ E ++ ++E L+ L K Sbjct: 832 TKVKPLLQVSRQE--EEMMAKEEELVKVREKQLAAENRLTEME-------TLQSQLMAEK 882 Query: 1059 RKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQ 1118 +L+ L+ E + E + +L K ++ E +L++++E+E+ LQ + K++Q Sbjct: 883 LQLQEQLQAETELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQ 942 Query: 1119 ARIEELEEEIEAERASRAKAEKQRSDLSRELEEISER---LEEAGGATSAQIEMNKKREA 1175 I+ELEE++E E ++R K + ++ +L+++ E LE+ + + ++ + R A Sbjct: 943 QNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIA 1002 Query: 1176 EFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEID 1235 EF + EE + + A L+ KH + +L E++ ++ +Q+LEK + +++ + Sbjct: 1003 EFTTNLTEEEEKS----KSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDST 1058 Query: 1236 DLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSR 1295 DL+ + L+ Q++ELK + +++ +L A R++ E+ + + Sbjct: 1059 DLSDQIAE--------------LQAQIAELKMQLAKKEE---ELQAALARVEEEAAQKNM 1101 Query: 1296 QLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEE 1355 L + L SQ+S EL+ LE E ++N + + + L+ + E+ Sbjct: 1102 ALKKIRELESQIS-----------ELQEDLESERASRNKAEKQKRDLGEELEALKTELED 1150 Query: 1356 EQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNA 1415 +S A Q SK EV + E +A +++E ++K +Q ++ E +E Sbjct: 1151 TLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKR 1210 Query: 1416 KCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEA 1475 A+LEK KQ L+NE +L +V+ + K++ + L E + K E Sbjct: 1211 VKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTE 1270 Query: 1476 SQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKI 1535 + L EL + +S + L ++ L+ ++ D E + E ++ L Sbjct: 1271 LADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTK 1330 Query: 1536 KKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRN 1595 KQVE EK + LEE E + + E +I + ++ +K +++ + E +++KR Sbjct: 1331 LKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCL-ETAEEVKRK 1389 Query: 1596 HIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGI 1655 + +E + + ++ + + + K +++ +L+++ + L+H + A + + + Sbjct: 1390 LQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQL 1449 Query: 1656 L---------------------KDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEEL 1694 L ++ + R+ E+ EQ A +ER + E+E+L Sbjct: 1450 LAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDL 1509 Query: 1695 RAT-------LEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQMQGEM 1747 ++ + + E+S++ EQ++ + +++ L + + + K +LE ++ M+ + Sbjct: 1510 MSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQF 1569 Query: 1748 EDILQ-EARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEA 1806 E LQ +EEK K+ + M EL+ E+ + +K +E +KDL+ +D A Sbjct: 1570 ERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSA 1629 Query: 1807 EQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKN 1866 + + KQ++KL+A++++ E++ + E + +++E+++K + + + ++ Sbjct: 1630 NKNRDEA-IKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEE 1688 Query: 1867 IL-------RLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIA 1919 + + Q D+L ++ + + A E+ A+ +L+ ELEE + ++ Sbjct: 1689 LAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELI 1748 Query: 1920 ESQVNKLRVKSREVHT 1935 ++ K ++ +++T Sbjct: 1749 NDRLKKANLQIDQINT 1764 Score = 187 bits (476), Expect = 7e-47 Identities = 213/913 (23%), Positives = 393/913 (43%), Gaps = 122/913 (13%) Query: 1083 DEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQR 1142 +E++ KE E+ ++ K + +++ +L A +L+E+++AE A+AE+ R Sbjct: 844 EEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEELR 903 Query: 1143 SDLS---RELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLR 1199 + L+ +ELEEI LE R + EE QH + Sbjct: 904 ARLTAKKQELEEICHDLEA----------------------RVEEEEERCQHLQAE---K 938 Query: 1200 KKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLE 1259 KK ++ EL EQ++ + +QKL+ EK V T +K K LE+ LE Sbjct: 939 KKMQQNIQELEEQLEEEESARQKLQLEK-------------VTTEAKLK-KLEEEQIILE 984 Query: 1260 DQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIE 1319 DQ +L ++++L+ D A EF+ L E+E L++ K I Sbjct: 985 DQNCKLA----KEKKLLEDRIA----------EFTTNLTEEEEKSKSLAKLKNKHEAMIT 1030 Query: 1320 ELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRT 1379 +L+ +L E K + L + D L +Q E Q AEL+ L+K E+ Sbjct: 1031 DLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALA 1090 Query: 1380 KYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVE 1439 + E +A Q+ L++ ++ L ++ +E +E+ A EK K+ L E+E L ++E Sbjct: 1091 RVEEEAAQKNMALKKIRE-LESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELE 1149 Query: 1440 RTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLD 1499 T + AA + + ++ + K+ EE EA +E R K A EE + Sbjct: 1150 DTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQ------KHSQAVEELAE 1203 Query: 1500 QLETLKRENKNLQQEISDLTEQIAEGGKRIHEL-------EKIKKQVEQEKCELQAALEE 1552 QLE KR NL++ L + E + L E +K+VE + ELQ E Sbjct: 1204 QLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNE 1263 Query: 1553 AEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQST---LDA 1609 E K+ ++Q+EL+ V +++ D + +L ++ + +Q T L Sbjct: 1264 GERVRTELADKVTKLQVELDNVTG----LLSQSDSKSSKLTKDFSALESQLQDTQELLQE 1319 Query: 1610 EIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRS 1669 E R + K++E + N QL + + D + ++D++ Sbjct: 1320 ENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGC 1379 Query: 1670 QEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSL 1729 E +E +++ L EE A ++ E+++ +QEL D V L H Q S Sbjct: 1380 LETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLL--VDLDH-QRQSA 1436 Query: 1730 INTKKKLETDISQMQGEMEDI----LQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHL 1785 N +KK + Q+ E + I +E AE +A++ T A +A L++ + A L Sbjct: 1437 CNLEKK-QKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAEL 1495 Query: 1786 ERMKKNMEQTVKDLQLRLDEAE------QLALKGGKKQIQKLEARVRELEGEVESEQKR- 1838 ER+ K ++DL D+ + + + ++Q+++++ ++ ELE E+++ + Sbjct: 1496 ERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAK 1555 Query: 1839 -----NAEAVKGLRKHE----------------RRVKELTYQTEEDRKNILRLQDLVDKL 1877 N +A+K + + R+V+E+ + E++RK KL Sbjct: 1556 LRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKL 1615 Query: 1878 QAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERAD---------IAESQVNKLRV 1928 + +K + + A + + + + RKLQ ++++ D +A+++ N+ ++ Sbjct: 1616 EMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKL 1675 Query: 1929 KSREVHTKVISEE 1941 KS E + EE Sbjct: 1676 KSMEAEMIQLQEE 1688 Score = 117 bits (292), Expect = 1e-25 Identities = 125/578 (21%), Positives = 257/578 (44%), Gaps = 68/578 (11%) Query: 1386 IQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAAC 1445 +Q + + EE K + ++ E+ + A N + +E + +L E L ++ C Sbjct: 838 LQVSRQEEEMMAKEEELVKVREKQLAAEN-RLTEMETLQSQLMAEKLQLQEQLQAETELC 896 Query: 1446 AALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLK 1505 A + EE A L A ++E + +L + EE ++ + L+ Sbjct: 897 A------------------EAEELRARLTAKKQELEEICHDL---EARVEEEEERCQHLQ 935 Query: 1506 RENKNLQQEISDLTEQIAE--GGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGK 1563 E K +QQ I +L EQ+ E ++ +LEK+ + + +K LEE + LE + K Sbjct: 936 AEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKK------LEEEQIILEDQNCK 989 Query: 1564 ILRIQLELNQVKSEVDRKIAEKDEE---IDQLKRNHIRIVESMQSTLDAEIRSRNDAIRL 1620 + + + L +E + E++E+ + +LK H ++ ++ L E + R + + Sbjct: 990 LAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKT 1049 Query: 1621 KKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMV 1680 ++K+EGD ++ Q+ AE L + L AL E+ Q M Sbjct: 1050 RRKLEGDSTDLSDQIAELQAQIAELKMQ-------LAKKEEELQAALARVEEEAAQKNMA 1102 Query: 1681 ERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINT-------- 1732 ++ L+++I EL+ LE SR AE++ D E ++ L T+ +++ Sbjct: 1103 LKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELR 1162 Query: 1733 -KKKLETDISQMQGEMEDILQEARNAE--EKAKKAITDAAMMAEELKKEQDTSAHLERMK 1789 K++ E +I + E E EA+ E +K +A+ + +AE+L++ + A+LE+ K Sbjct: 1163 SKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEE---LAEQLEQTKRVKANLEKAK 1219 Query: 1790 KNMEQTVKDLQLRLDEAEQLALKG---GKKQIQKLEARVRELEGEVESEQKRNAEAVKGL 1846 QT+++ + L ++ L+G + + +K+EA+++EL+ + ++ E + Sbjct: 1220 ----QTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKV 1275 Query: 1847 RKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQ 1906 K + + +T + +L L+++++ + +E Q + K ++++ Sbjct: 1276 TKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVE 1335 Query: 1907 HE-------LEEAEERADIAESQVNKLRVKSREVHTKV 1937 E LEE EE E Q+ L + ++ K+ Sbjct: 1336 DEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKM 1373 Score = 86.7 bits (213), Expect = 2e-16 Identities = 75/379 (19%), Positives = 167/379 (44%), Gaps = 33/379 (8%) Query: 837 KLFFKIKPLLKSAETEKEMATMKEEFQKIKDELAKS----EAKRKELEEKMVTLLKEKND 892 KL ++ A+ E+++ E+ ++ K +L + EA+ ++ ++ + + Sbjct: 1555 KLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKK 1614 Query: 893 LQLQVQAEAEGLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDE 952 L++ ++ + A + D+ IK +L+A++K+ +D E+ A+ ++ E + Sbjct: 1615 LEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKK 1674 Query: 953 CSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQT 1012 ++ ++ L+ LA E+ K + + L +E+A A +EK+ L+ Q Sbjct: 1675 LKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQL 1734 Query: 1013 LDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKK-------LRMDLERAKRKL---- 1061 ++L+ E+ + K Q+D + L E+ R LER ++L Sbjct: 1735 EEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKL 1794 Query: 1062 ---EGDLKLAQE-SIMDIENEKQQLDEKL--------------KKKEFEISNLQSKIEDE 1103 EG +K + SI +E + QL+E+L ++ E ++ ++ +++DE Sbjct: 1795 QEMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDE 1854 Query: 1104 QALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGAT 1163 + Q + + + R+++L+ ++E +A R L RELE+ +E + Sbjct: 1855 RRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETADAMNREV 1914 Query: 1164 SAQIEMNKKREAEFQKMRR 1182 S+ ++ + F RR Sbjct: 1915 SSLKNKLRRGDLPFVVPRR 1933 Score = 42.7 bits (99), Expect = 0.003 Identities = 69/332 (20%), Positives = 142/332 (42%), Gaps = 67/332 (20%) Query: 783 RDDKLAQLITRTQARCRGFLARVEYQRMVERREAIFCIQYNIRSFMNVKHWPWMKLFFKI 842 RD+ + QL + QA+ + + ++ R R E + + N + +++ ++ Sbjct: 1633 RDEAIKQL-RKLQAQMKDCMRELDDTR-ASREEILAQAKENEKKLKSME-----AEMIQL 1685 Query: 843 KPLLKSAETEKEMATMKEEFQKIKDELAKSEAK-------RKELEEKMVTLLKEKNDLQL 895 + L +AE K A ++E ++ DE+A S K ++ LE ++ L +E + Q Sbjct: 1686 QEELAAAERAKRQA--QQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQG 1743 Query: 896 QVQAEAEGLADAEERCDQLI--------------KTKIQLEAKIKEVTERAEDEE----- 936 + + L A + DQ+ + QLE + KE+ + ++ E Sbjct: 1744 NTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKS 1803 Query: 937 EINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIA 996 + A +TA LE + ++L++ +D+ KE+ A +V+ Sbjct: 1804 KYKASITA----LEAKIAQLEEQLDN-------ETKERQAACKQVR-------------- 1838 Query: 997 KLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLER 1056 + +K L++ Q D+ + E + KA +L+Q L+ LE+ ++ Sbjct: 1839 ---RTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQ----LKRQLEEAEEEAQRANA 1891 Query: 1057 AKRKLEGDLKLAQESIMDIENEKQQLDEKLKK 1088 ++RKL+ +L+ A E+ + E L KL++ Sbjct: 1892 SRRKLQRELEDATETADAMNREVSSLKNKLRR 1923 Score = 38.5 bits (88), Expect = 0.065 Identities = 36/149 (24%), Positives = 70/149 (46%), Gaps = 13/149 (8%) Query: 1799 LQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTY 1858 LQ+ E E +A + ++++ + E+E+ Q + L++ + EL Sbjct: 838 LQVSRQEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCA 897 Query: 1859 QTEEDRKNIL----RLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEE 1914 + EE R + L+++ L+A+V EE EE+ A+ +K+Q ++E EE Sbjct: 898 EAEELRARLTAKKQELEEICHDLEARV-------EEEEERCQHLQAEKKKMQQNIQELEE 950 Query: 1915 RADIAESQVNKLRVK--SREVHTKVISEE 1941 + + ES KL+++ + E K + EE Sbjct: 951 QLEEEESARQKLQLEKVTTEAKLKKLEEE 979 >gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens] Length = 1995 Score = 1306 bits (3380), Expect = 0.0 Identities = 722/1907 (37%), Positives = 1151/1907 (60%), Gaps = 21/1907 (1%) Query: 34 AKTSVFVAEPKESFVKGTIQSREGGKVTVK-TEGGATLTVKDDQVFPMNPPKYDKIEDMA 92 A+ V+V F ++ + V+ E G L + DQ+ MNPPK+ K EDMA Sbjct: 52 ARRLVWVPSELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMA 111 Query: 93 MMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYKPEVVTAYRGKKRQEAP 152 +T L+E +VL+NL+ERY + +IYTYSGLFCV +NPYK LP+Y +V YRGKKR E P Sbjct: 112 ELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVP 171 Query: 153 PHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKEEITS 212 PH++++++ AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY A +A + + +KE Sbjct: 172 PHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEP--- 228 Query: 213 GKIQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLE 272 + G LE Q++ ANP+LEAFGNAKTV+NDNSSRFGKFIRI+F G + A+IETYLLE Sbjct: 229 -GVPGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLLE 287 Query: 273 KSRVVFQLKAERSYHIFYQITSNKKPELIEMLLITTNPYDYPFVSQGEISVASIDDQEEL 332 KSR + Q K E S+HIFYQ+ +L LL+ + Y F++ G S ++E Sbjct: 288 KSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSH-YRFLTNGPSSSPG-QERELF 345 Query: 333 MATDSAIDILGFTNEEKVSIYKLTGAVMHYGNLKFKQKQREEQAEPDGTEVADKAAYLQS 392 T ++ +LGF++EE +S+ ++ AV+ +GN+ K+++ +QA A K L Sbjct: 346 QETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRLLG 405 Query: 393 LNSADLLKALCYPRVKVGNEYVTKGQTVEQVSNAVGALAKAVYEKMFLWMVARINQQLDT 452 L D +AL PR+KVG +YV K QT EQ A+ ALAKA YE++F W+V R+N+ LD Sbjct: 406 LGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALD- 464 Query: 453 KQPRQ--YFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIE 510 + PRQ F+G+LDIAGFEIF NS EQLCIN+TNEKLQQ FNH MFVLEQEEY++EGI Sbjct: 465 RSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIP 524 Query: 511 WTFIDFGMDLAACIELIEKPM---GIFSILEEECMFPKATDTSFKNKLYDQHLGKSANFQ 567 WTF+DFG+DL CI+LIE+P G+ ++L+EEC FPKATD SF K+ Q G FQ Sbjct: 525 WTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVA-QEQGGHPKFQ 583 Query: 568 KPKVVKGKAEAHFALIHYAGVVDYNITGWLEKNKDPLNETVVGLYQKSAMKTLAQLFS-- 625 +P+ ++ +A+ F+++HYAG VDY WL KN DPLN+ V L +S + A+++ Sbjct: 584 RPRHLRDQAD--FSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKDV 641 Query: 626 -GAQTAEGEGAGGGAKKGGKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPNET 684 G E + G GG+ + F+TV L++E+L++LM L +T+P FVRCI+PN Sbjct: 642 EGIVGLEQVSSLGDGPPGGRPRRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHE 701 Query: 685 KTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQFIDS 744 K G +E LVL QLRCNGVLEGIRICR+GFP+RIL+ +F+QRY++L +AIP+G F+D Sbjct: 702 KRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPKG-FMDG 760 Query: 745 KKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDDKLAQLITRTQARCRGFLAR 804 K+A EK++ ++++D Y+ G +K+FF+AG+L LEE RD K+ +I QA RG+LAR Sbjct: 761 KQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLAR 820 Query: 805 VEYQRMVERREAIFCIQYNIRSFMNVKHWPWMKLFFKIKPLLKSAETEKEMATMKEEFQK 864 +Q+ +++ A+ +Q N +++ ++HW W +LF K+KPLL+ ++ + +E QK Sbjct: 821 RAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQELQK 880 Query: 865 IKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCDQLIKTKIQLEAK 924 +++ +S + EL+ ++ L +E+ L Q++AEAE A+AEE +L K +LE Sbjct: 881 VQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQELELV 940 Query: 925 IKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNL 984 + E+ R +EEE + ++ +K++L+ EL+ ++ E K++ EK TE K+K Sbjct: 941 VSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKF 1000 Query: 985 TEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSL 1044 E++ L++ +KL+KE+K L++ + EE+KV +L K ++K E + D+E L Sbjct: 1001 EEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRL 1060 Query: 1045 EQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQ 1104 +E+K R +LE+ KR+L+G+ QE +++ + ++L +L +KE E+ ++ EDE Sbjct: 1061 RKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEG 1120 Query: 1105 ALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATS 1164 QL K ++E QA + E +E++E+ER +R KAEKQR DL ELE + LE+ +T+ Sbjct: 1121 GARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTN 1180 Query: 1165 AQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLE 1224 AQ E+ KRE E ++++ LEE T HEA LR++H ++ EL EQ++ +R K E Sbjct: 1181 AQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWE 1240 Query: 1225 KEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRG 1284 K + ++ E+ +L + + ++ A+ E+ R LE QL E++ + + +R + + Sbjct: 1241 KTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQ 1300 Query: 1285 RLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRH 1344 R Q E S L+E E+ +LS+ + Q+ + + L+EE +AK AL +++ Sbjct: 1301 RAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEA 1360 Query: 1345 DCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQ 1404 + LREQ EEE ++ R L A ++++WR + E +A E EEA+++ A+ + Sbjct: 1361 EAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEA-GALEAGEEARRRAAREAE 1419 Query: 1405 AAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQ 1464 A + + LE+ ++RLQ E++D +D+E+ + L+KKQR FD++LAE K Sbjct: 1420 ALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKA 1479 Query: 1465 KCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAE 1524 E E ++ E R + A EE + E L+R+N+ L+ E+ L + Sbjct: 1480 AVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDD 1539 Query: 1525 GGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAE 1584 GK +HELE+ + EQ +L+A + E E L E LR+++ + +K++ +R + Sbjct: 1540 VGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQG 1599 Query: 1585 KDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAE 1644 +DE ++ +R + + + D E + R A+ +KK+EG+L E++ Q+ A + E Sbjct: 1600 RDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEE 1659 Query: 1645 ALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERS 1704 A++ R Q +K+ +++ S+E++ Q E+R L+AE+ L+ L ++R+ Sbjct: 1660 AVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRA 1719 Query: 1705 RKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKA 1764 R+ A+Q+ + ++ V + +++ K++LE + Q++ E+E+ + ++ +K Sbjct: 1720 RRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKL 1779 Query: 1765 ITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEAR 1824 + + EL E+ SA E ++ +E+ +++L+ RL E + A K I LE++ Sbjct: 1780 LLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESK 1839 Query: 1825 VRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSY 1884 + + E ++E E + + K +R+ E+R+KE+ Q EE+R+ +L+D ++K +VK Sbjct: 1840 LAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQL 1899 Query: 1885 KRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAESQVNKLRVKSR 1931 KRQ EEAEE+++ A R+LQ ELE+ E A+ +V LR + R Sbjct: 1900 KRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLR 1946 Score = 224 bits (572), Expect = 5e-58 Identities = 195/932 (20%), Positives = 421/932 (45%), Gaps = 48/932 (5%) Query: 859 KEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCD------ 912 ++E +K+K L + + EL+E+MV + +L+ Q+ + E L A R + Sbjct: 1067 RQELEKLKRRL---DGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGAR 1123 Query: 913 -QLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVE 971 QL+K+ + +A + E E E E + ++R L +E L+ +++D TL Sbjct: 1124 AQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELED---TLDSTN 1180 Query: 972 KEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVN----TLT 1027 ++ + + +TE L+E + L++ H Q L +L + ++ Sbjct: 1181 AQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWE 1240 Query: 1028 KAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLK 1087 K ++ LE +V +L L + R + E+ +R+LE L+ Q D E + + EKL+ Sbjct: 1241 KTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQ 1300 Query: 1088 KKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSR 1147 + + E+ N+ + + ++ I+L K++ +A++ + +E ++ E ++ + + Sbjct: 1301 RAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEA 1360 Query: 1148 ELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADS-- 1205 E + E+LEE A + +A+ + RR EE EA R+ ++ Sbjct: 1361 EAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEA 1420 Query: 1206 ----VAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQ 1261 +AE E +D L+R +++L++E + M+++ V T+ K + +++ E++ Sbjct: 1421 LTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLA--EEK 1478 Query: 1262 LSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEEL 1321 + L++ EE ++ A+ + + +R L+E++ +L R +A ++E L Sbjct: 1479 AAVLRAVEERERA-----EAEGREREARALSLTRALEEEQEAREELERQNRALRAELEAL 1533 Query: 1322 KRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKY 1381 ++ K+ + L A + + + LR Q E ++ + A + V +T++ Sbjct: 1534 LSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQH 1593 Query: 1382 ETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERT 1441 E D R E EE +++LA++L+ AE + + +++L+ E+E+L + Sbjct: 1594 ERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASA 1653 Query: 1442 NAACAALDKKQRNFDKILAEWKQKCEETHAELEA-------SQKEARSLGTELFKIKNAY 1494 K+ R + E ++ EET E S+K + L E+ +++ Sbjct: 1654 GQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQ--- 1710 Query: 1495 EESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAE 1554 ++L R + QQ+ ++ +++A G + + K+Q+E +L+ LEE + Sbjct: 1711 ----EELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQ 1766 Query: 1555 ASLEHEEGKILRIQLELNQVKSEV--DRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIR 1612 ++ E + ++ L++ + +E+ +R + K E Q I+ + DA R Sbjct: 1767 SNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGAR 1826 Query: 1613 SRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQED 1672 +R+ +E L + E QL R + + R + LK+ + +++ R + Sbjct: 1827 ARHKMTIAA--LESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQ 1884 Query: 1673 LKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINT 1732 L++QL R L+ ++EE + + R+ ++EL D +E + ++ + T+L N Sbjct: 1885 LRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNR 1944 Query: 1733 KKKLETDISQMQGEMEDILQEARNAEEKAKKA 1764 ++ + L+E ++E+A++A Sbjct: 1945 LRRGPLTFTTRTVRQVFRLEEGVASDEEAEEA 1976 Score = 171 bits (434), Expect = 5e-42 Identities = 178/881 (20%), Positives = 381/881 (43%), Gaps = 83/881 (9%) Query: 1099 KIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEE 1158 +++ Q L Q +++ ELQ R+ +LEEE RA A+ + ++L E EE RL Sbjct: 877 ELQKVQELQQQSAREVGELQGRVAQLEEE----RARLAEQLRAEAELCAEAEETRGRLAA 932 Query: 1159 AGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQR 1218 + + R E ++ R ++ T +K+ + EL ++ + Sbjct: 933 RKQELELVVSELEARVGEEEECSRQMQ-----------TEKKRLQQHIQELEAHLEAEEG 981 Query: 1219 VKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLIND 1278 +QKL+ EK + ++ ++ + L K + LED+L+E S+ E++ + Sbjct: 982 ARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKS 1041 Query: 1279 LTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHA 1338 L R + + + +L ++E +L + K+ + EL+ Q+ E+ + L Sbjct: 1042 LNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQ 1101 Query: 1339 LQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKK 1398 L + + E+E ++A+L ++L +A +A+ + E++ + RT+ E+ ++ Sbjct: 1102 LGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKA-EKQRRD 1160 Query: 1399 LAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVER-TNAACAALDKKQRNFDK 1457 L + L+A +E + ++ + + + EV +L +E T AA+ + ++ + Sbjct: 1161 LGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQ 1220 Query: 1458 ILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISD 1517 L E ++ E+ A +K +L E+ +++ L L+T ++E + ++ Sbjct: 1221 ALGELAEQLEQARRGKGAWEKTRLALEAEVSELR----AELSSLQTARQEGEQRRRR--- 1273 Query: 1518 LTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSE 1577 L Q+ E R + E+ + + ++ QA LE +L E K +R+ EL+ +++ Sbjct: 1274 LELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQ 1333 Query: 1578 VDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNH 1637 + Q L E R++ + ME + + QL Sbjct: 1334 L----------------------HDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEE 1371 Query: 1638 ANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRAT 1697 A R + Q L + + ++ + E +E R A L + E T Sbjct: 1372 EAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTET 1431 Query: 1698 LEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNA 1757 +++ ER R+ +QEL DA+ ++ ++L ++K + +++ + + ++E A Sbjct: 1432 VDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERA 1491 Query: 1758 EEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAE------QLAL 1811 E + ++ A + L++EQ+ LER + + ++ L D+ + A Sbjct: 1492 EAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERAC 1551 Query: 1812 KGGKKQIQKLEARVRELEGEV---ESEQKRNAEAVKGLR-KHER---------------- 1851 + ++ L A+V ELE E+ E + R V+ L+ +HER Sbjct: 1552 RVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQL 1611 Query: 1852 --RVKELTYQTEEDRKNIL-------RLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKF 1902 ++++ + +E+RK +L+ +++L+A++ S + EEA +Q A+ Sbjct: 1612 AKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQM 1671 Query: 1903 RKLQHELEEAEERAD--IAESQVNKLRVKSREVHTKVISEE 1941 ++L E+EE + ++++ ++ R+K E + EE Sbjct: 1672 KELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEE 1712 Score = 117 bits (292), Expect = 1e-25 Identities = 130/642 (20%), Positives = 262/642 (40%), Gaps = 49/642 (7%) Query: 1339 LQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKK 1398 LQ+ + ++E ++ ELQ +++ E A+ + +A + E EE + + Sbjct: 871 LQARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEA-ELCAEAEETRGR 929 Query: 1399 LAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALD--KKQRNFD 1456 LA R Q E V + A+ E+ +++Q E + L ++ A A + +++ + Sbjct: 930 LAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLE 989 Query: 1457 KILAEWKQKCEETHAELEASQ-----KEARSLGTELFKIKNAYEESLDQLETLKRENKNL 1511 K+ E K K E L Q KE + L L + + E +++++L + Sbjct: 990 KVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKY 1049 Query: 1512 QQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLEL 1571 + I+D+ +++ + K ELEK+K++++ E ELQ + E + E ++ R + EL Sbjct: 1050 EATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEEL 1109 Query: 1572 NQVKS-----------------EVDRKIAEKDEEID----------QLKRNHIRIVESMQ 1604 + E +AE E+++ + +R+ +E+++ Sbjct: 1110 QAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALR 1169 Query: 1605 STLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLD 1664 L+ + S N L+ K E ++ E++ L R+ A++ R G L Sbjct: 1170 GELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQA------LG 1223 Query: 1665 DALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHT 1724 + E + E+ L+AE+ ELRA L + +R+ EQ ++Q + Sbjct: 1224 ELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQG 1283 Query: 1725 QNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAH 1784 + + + + + Q E+E++ AE K + + + +L Q+ Sbjct: 1284 RAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQE 1343 Query: 1785 LERMK-------KNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQK 1837 R K + ME L+ +L+E E A + +++Q +A++ E E E Sbjct: 1344 ETRAKLALGSRVRAMEAEAAGLREQLEE-EAAARERAGRELQTAQAQLSEWRRRQEEEAG 1402 Query: 1838 RNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNT 1897 + R+ R + LT + E + + RL+ +LQ ++ E+ + +T Sbjct: 1403 ALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVST 1462 Query: 1898 NLAKFRKLQHELEEAEERADIAESQVNKLRVKSREVHTKVIS 1939 K RK L E + A + + + RE + +S Sbjct: 1463 LEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALS 1504 >gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens] Length = 2003 Score = 1305 bits (3378), Expect = 0.0 Identities = 722/1911 (37%), Positives = 1151/1911 (60%), Gaps = 21/1911 (1%) Query: 34 AKTSVFVAEPKESFVKGTIQSREGGKVTVK-TEGGATLTVKDDQVFPMNPPKYDKIEDMA 92 A+ V+V F ++ + V+ E G L + DQ+ MNPPK+ K EDMA Sbjct: 52 ARRLVWVPSELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMA 111 Query: 93 MMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYKPEVVTAYRGKKRQEAP 152 +T L+E +VL+NL+ERY + +IYTYSGLFCV +NPYK LP+Y +V YRGKKR E P Sbjct: 112 ELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVP 171 Query: 153 PHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKEEITS 212 PH++++++ AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY A +A + + +KE Sbjct: 172 PHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVP 231 Query: 213 GKIQ----GTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIET 268 + G LE Q++ ANP+LEAFGNAKTV+NDNSSRFGKFIRI+F G + A+IET Sbjct: 232 ASVSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIET 291 Query: 269 YLLEKSRVVFQLKAERSYHIFYQITSNKKPELIEMLLITTNPYDYPFVSQGEISVASIDD 328 YLLEKSR + Q K E S+HIFYQ+ +L LL+ + Y F++ G S + Sbjct: 292 YLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSH-YRFLTNGPSSSPG-QE 349 Query: 329 QEELMATDSAIDILGFTNEEKVSIYKLTGAVMHYGNLKFKQKQREEQAEPDGTEVADKAA 388 +E T ++ +LGF++EE +S+ ++ AV+ +GN+ K+++ +QA A K Sbjct: 350 RELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLC 409 Query: 389 YLQSLNSADLLKALCYPRVKVGNEYVTKGQTVEQVSNAVGALAKAVYEKMFLWMVARINQ 448 L L D +AL PR+KVG +YV K QT EQ A+ ALAKA YE++F W+V R+N+ Sbjct: 410 RLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNR 469 Query: 449 QLDTKQPRQ--YFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKK 506 LD + PRQ F+G+LDIAGFEIF NS EQLCIN+TNEKLQQ FNH MFVLEQEEY++ Sbjct: 470 ALD-RSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQR 528 Query: 507 EGIEWTFIDFGMDLAACIELIEKPM---GIFSILEEECMFPKATDTSFKNKLYDQHLGKS 563 EGI WTF+DFG+DL CI+LIE+P G+ ++L+EEC FPKATD SF K+ Q G Sbjct: 529 EGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVA-QEQGGH 587 Query: 564 ANFQKPKVVKGKAEAHFALIHYAGVVDYNITGWLEKNKDPLNETVVGLYQKSAMKTLAQL 623 FQ+P+ ++ +A+ F+++HYAG VDY WL KN DPLN+ V L +S + A++ Sbjct: 588 PKFQRPRHLRDQAD--FSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEI 645 Query: 624 FS---GAQTAEGEGAGGGAKKGGKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCII 680 + G E + G GG+ + F+TV L++E+L++LM L +T+P FVRCI+ Sbjct: 646 WKDVEGIVGLEQVSSLGDGPPGGRPRRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCIV 705 Query: 681 PNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQ 740 PN K G +E LVL QLRCNGVLEGIRICR+GFP+RIL+ +F+QRY++L +AIP+G Sbjct: 706 PNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPKG- 764 Query: 741 FIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDDKLAQLITRTQARCRG 800 F+D K+A EK++ ++++D Y+ G +K+FF+AG+L LEE RD K+ +I QA RG Sbjct: 765 FMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARG 824 Query: 801 FLARVEYQRMVERREAIFCIQYNIRSFMNVKHWPWMKLFFKIKPLLKSAETEKEMATMKE 860 +LAR +Q+ +++ A+ +Q N +++ ++HW W +LF K+KPLL+ ++ + + Sbjct: 825 YLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQ 884 Query: 861 EFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCDQLIKTKIQ 920 E QK+++ +S + EL+ ++ L +E+ L Q++AEAE A+AEE +L K + Sbjct: 885 ELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQE 944 Query: 921 LEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENK 980 LE + E+ R +EEE + ++ +K++L+ EL+ ++ E K++ EK TE K Sbjct: 945 LELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAK 1004 Query: 981 VKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDL 1040 +K E++ L++ +KL+KE+K L++ + EE+KV +L K ++K E + D+ Sbjct: 1005 MKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADM 1064 Query: 1041 EGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKI 1100 E L +E+K R +LE+ KR+L+G+ QE +++ + ++L +L +KE E+ ++ Sbjct: 1065 EDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARA 1124 Query: 1101 EDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAG 1160 EDE QL K ++E QA + E +E++E+ER +R KAEKQR DL ELE + LE+ Sbjct: 1125 EDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTL 1184 Query: 1161 GATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVK 1220 +T+AQ E+ KRE E ++++ LEE T HEA LR++H ++ EL EQ++ +R K Sbjct: 1185 DSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGK 1244 Query: 1221 QKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLT 1280 EK + ++ E+ +L + + ++ A+ E+ R LE QL E++ + + +R + Sbjct: 1245 GAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAA 1304 Query: 1281 AQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQ 1340 + R Q E S L+E E+ +LS+ + Q+ + + L+EE +AK AL ++ Sbjct: 1305 EKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVR 1364 Query: 1341 SSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLA 1400 + + LREQ EEE ++ R L A ++++WR + E +A E EEA+++ A Sbjct: 1365 AMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEA-GALEAGEEARRRAA 1423 Query: 1401 QRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILA 1460 + +A + + LE+ ++RLQ E++D +D+E+ + L+KKQR FD++LA Sbjct: 1424 REAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLA 1483 Query: 1461 EWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTE 1520 E K E E ++ E R + A EE + E L+R+N+ L+ E+ L Sbjct: 1484 EEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLS 1543 Query: 1521 QIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDR 1580 + GK +HELE+ + EQ +L+A + E E L E LR+++ + +K++ +R Sbjct: 1544 SKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHER 1603 Query: 1581 KIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANR 1640 + +DE ++ +R + + + D E + R A+ +KK+EG+L E++ Q+ A + Sbjct: 1604 DLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQ 1663 Query: 1641 MAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQ 1700 EA++ R Q +K+ +++ S+E++ Q E+R L+AE+ L+ L Sbjct: 1664 GKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAA 1723 Query: 1701 TERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEK 1760 ++R+R+ A+Q+ + ++ V + +++ K++LE + Q++ E+E+ + ++ Sbjct: 1724 SDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDR 1783 Query: 1761 AKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQK 1820 +K + + EL E+ SA E ++ +E+ +++L+ RL E + A K I Sbjct: 1784 YRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAA 1843 Query: 1821 LEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAK 1880 LE+++ + E ++E E + + K +R+ E+R+KE+ Q EE+R+ +L+D ++K + Sbjct: 1844 LESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLR 1903 Query: 1881 VKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAESQVNKLRVKSR 1931 VK KRQ EEAEE+++ A R+LQ ELE+ E A+ +V LR + R Sbjct: 1904 VKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLR 1954 Score = 224 bits (572), Expect = 5e-58 Identities = 195/932 (20%), Positives = 421/932 (45%), Gaps = 48/932 (5%) Query: 859 KEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCD------ 912 ++E +K+K L + + EL+E+MV + +L+ Q+ + E L A R + Sbjct: 1075 RQELEKLKRRL---DGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGAR 1131 Query: 913 -QLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVE 971 QL+K+ + +A + E E E E + ++R L +E L+ +++D TL Sbjct: 1132 AQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELED---TLDSTN 1188 Query: 972 KEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVN----TLT 1027 ++ + + +TE L+E + L++ H Q L +L + ++ Sbjct: 1189 AQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWE 1248 Query: 1028 KAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLK 1087 K ++ LE +V +L L + R + E+ +R+LE L+ Q D E + + EKL+ Sbjct: 1249 KTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQ 1308 Query: 1088 KKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSR 1147 + + E+ N+ + + ++ I+L K++ +A++ + +E ++ E ++ + + Sbjct: 1309 RAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEA 1368 Query: 1148 ELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADS-- 1205 E + E+LEE A + +A+ + RR EE EA R+ ++ Sbjct: 1369 EAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEA 1428 Query: 1206 ----VAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQ 1261 +AE E +D L+R +++L++E + M+++ V T+ K + +++ E++ Sbjct: 1429 LTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLA--EEK 1486 Query: 1262 LSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEEL 1321 + L++ EE ++ A+ + + +R L+E++ +L R +A ++E L Sbjct: 1487 AAVLRAVEERERA-----EAEGREREARALSLTRALEEEQEAREELERQNRALRAELEAL 1541 Query: 1322 KRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKY 1381 ++ K+ + L A + + + LR Q E ++ + A + V +T++ Sbjct: 1542 LSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQH 1601 Query: 1382 ETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERT 1441 E D R E EE +++LA++L+ AE + + +++L+ E+E+L + Sbjct: 1602 ERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASA 1661 Query: 1442 NAACAALDKKQRNFDKILAEWKQKCEETHAELEA-------SQKEARSLGTELFKIKNAY 1494 K+ R + E ++ EET E S+K + L E+ +++ Sbjct: 1662 GQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQ--- 1718 Query: 1495 EESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAE 1554 ++L R + QQ+ ++ +++A G + + K+Q+E +L+ LEE + Sbjct: 1719 ----EELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQ 1774 Query: 1555 ASLEHEEGKILRIQLELNQVKSEV--DRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIR 1612 ++ E + ++ L++ + +E+ +R + K E Q I+ + DA R Sbjct: 1775 SNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGAR 1834 Query: 1613 SRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQED 1672 +R+ +E L + E QL R + + R + LK+ + +++ R + Sbjct: 1835 ARHKMTIAA--LESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQ 1892 Query: 1673 LKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINT 1732 L++QL R L+ ++EE + + R+ ++EL D +E + ++ + T+L N Sbjct: 1893 LRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNR 1952 Query: 1733 KKKLETDISQMQGEMEDILQEARNAEEKAKKA 1764 ++ + L+E ++E+A++A Sbjct: 1953 LRRGPLTFTTRTVRQVFRLEEGVASDEEAEEA 1984 Score = 171 bits (434), Expect = 5e-42 Identities = 178/881 (20%), Positives = 381/881 (43%), Gaps = 83/881 (9%) Query: 1099 KIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEE 1158 +++ Q L Q +++ ELQ R+ +LEEE RA A+ + ++L E EE RL Sbjct: 885 ELQKVQELQQQSAREVGELQGRVAQLEEE----RARLAEQLRAEAELCAEAEETRGRLAA 940 Query: 1159 AGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQR 1218 + + R E ++ R ++ T +K+ + EL ++ + Sbjct: 941 RKQELELVVSELEARVGEEEECSRQMQ-----------TEKKRLQQHIQELEAHLEAEEG 989 Query: 1219 VKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLIND 1278 +QKL+ EK + ++ ++ + L K + LED+L+E S+ E++ + Sbjct: 990 ARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKS 1049 Query: 1279 LTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHA 1338 L R + + + +L ++E +L + K+ + EL+ Q+ E+ + L Sbjct: 1050 LNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQ 1109 Query: 1339 LQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKK 1398 L + + E+E ++A+L ++L +A +A+ + E++ + RT+ E+ ++ Sbjct: 1110 LGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKA-EKQRRD 1168 Query: 1399 LAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVER-TNAACAALDKKQRNFDK 1457 L + L+A +E + ++ + + + EV +L +E T AA+ + ++ + Sbjct: 1169 LGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQ 1228 Query: 1458 ILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISD 1517 L E ++ E+ A +K +L E+ +++ L L+T ++E + ++ Sbjct: 1229 ALGELAEQLEQARRGKGAWEKTRLALEAEVSELR----AELSSLQTARQEGEQRRRR--- 1281 Query: 1518 LTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSE 1577 L Q+ E R + E+ + + ++ QA LE +L E K +R+ EL+ +++ Sbjct: 1282 LELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQ 1341 Query: 1578 VDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNH 1637 + Q L E R++ + ME + + QL Sbjct: 1342 L----------------------HDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEE 1379 Query: 1638 ANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRAT 1697 A R + Q L + + ++ + E +E R A L + E T Sbjct: 1380 EAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTET 1439 Query: 1698 LEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNA 1757 +++ ER R+ +QEL DA+ ++ ++L ++K + +++ + + ++E A Sbjct: 1440 VDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERA 1499 Query: 1758 EEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAE------QLAL 1811 E + ++ A + L++EQ+ LER + + ++ L D+ + A Sbjct: 1500 EAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERAC 1559 Query: 1812 KGGKKQIQKLEARVRELEGEV---ESEQKRNAEAVKGLR-KHER---------------- 1851 + ++ L A+V ELE E+ E + R V+ L+ +HER Sbjct: 1560 RVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQL 1619 Query: 1852 --RVKELTYQTEEDRKNIL-------RLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKF 1902 ++++ + +E+RK +L+ +++L+A++ S + EEA +Q A+ Sbjct: 1620 AKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQM 1679 Query: 1903 RKLQHELEEAEERAD--IAESQVNKLRVKSREVHTKVISEE 1941 ++L E+EE + ++++ ++ R+K E + EE Sbjct: 1680 KELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEE 1720 Score = 117 bits (292), Expect = 1e-25 Identities = 130/642 (20%), Positives = 262/642 (40%), Gaps = 49/642 (7%) Query: 1339 LQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKK 1398 LQ+ + ++E ++ ELQ +++ E A+ + +A + E EE + + Sbjct: 879 LQARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEA-ELCAEAEETRGR 937 Query: 1399 LAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALD--KKQRNFD 1456 LA R Q E V + A+ E+ +++Q E + L ++ A A + +++ + Sbjct: 938 LAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLE 997 Query: 1457 KILAEWKQKCEETHAELEASQ-----KEARSLGTELFKIKNAYEESLDQLETLKRENKNL 1511 K+ E K K E L Q KE + L L + + E +++++L + Sbjct: 998 KVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKY 1057 Query: 1512 QQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLEL 1571 + I+D+ +++ + K ELEK+K++++ E ELQ + E + E ++ R + EL Sbjct: 1058 EATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEEL 1117 Query: 1572 NQVKS-----------------EVDRKIAEKDEEID----------QLKRNHIRIVESMQ 1604 + E +AE E+++ + +R+ +E+++ Sbjct: 1118 QAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALR 1177 Query: 1605 STLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLD 1664 L+ + S N L+ K E ++ E++ L R+ A++ R G L Sbjct: 1178 GELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQA------LG 1231 Query: 1665 DALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHT 1724 + E + E+ L+AE+ ELRA L + +R+ EQ ++Q + Sbjct: 1232 ELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQG 1291 Query: 1725 QNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAH 1784 + + + + + Q E+E++ AE K + + + +L Q+ Sbjct: 1292 RAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQE 1351 Query: 1785 LERMK-------KNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQK 1837 R K + ME L+ +L+E E A + +++Q +A++ E E E Sbjct: 1352 ETRAKLALGSRVRAMEAEAAGLREQLEE-EAAARERAGRELQTAQAQLSEWRRRQEEEAG 1410 Query: 1838 RNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNT 1897 + R+ R + LT + E + + RL+ +LQ ++ E+ + +T Sbjct: 1411 ALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVST 1470 Query: 1898 NLAKFRKLQHELEEAEERADIAESQVNKLRVKSREVHTKVIS 1939 K RK L E + A + + + RE + +S Sbjct: 1471 LEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALS 1512 >gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens] Length = 2036 Score = 1293 bits (3345), Expect = 0.0 Identities = 722/1944 (37%), Positives = 1151/1944 (59%), Gaps = 54/1944 (2%) Query: 34 AKTSVFVAEPKESFVKGTIQSREGGKVTVK-TEGGATLTVKDDQVFPMNPPKYDKIEDMA 92 A+ V+V F ++ + V+ E G L + DQ+ MNPPK+ K EDMA Sbjct: 52 ARRLVWVPSELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMA 111 Query: 93 MMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYKPEVVTAYRGKKRQEAP 152 +T L+E +VL+NL+ERY + +IYTYSGLFCV +NPYK LP+Y +V YRGKKR E P Sbjct: 112 ELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVP 171 Query: 153 PHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKEEITS 212 PH++++++ AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY A +A + + +KE Sbjct: 172 PHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVP 231 Query: 213 GKIQ----GTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIET 268 + G LE Q++ ANP+LEAFGNAKTV+NDNSSRFGKFIRI+F G + A+IET Sbjct: 232 ASVSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIET 291 Query: 269 YLLEKSRVVFQLKAERSYHIFYQITSNKKPELIEMLLITTNPYDYPFVSQGEISVASIDD 328 YLLEKSR + Q K E S+HIFYQ+ +L LL+ + Y F++ G S + Sbjct: 292 YLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSH-YRFLTNGPSSSPG-QE 349 Query: 329 QEELMATDSAIDILGFTNEEKVSIYKLTGAVMHYGNLKFKQKQREEQAEPDGTEVADKAA 388 +E T ++ +LGF++EE +S+ ++ AV+ +GN+ K+++ +QA A K Sbjct: 350 RELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLC 409 Query: 389 YLQSLNSADLLKALCYPRVKVGNEYVTKGQTVEQVSNAVGALAKAVYEKMFLWMVARINQ 448 L L D +AL PR+KVG +YV K QT EQ A+ ALAKA YE++F W+V R+N+ Sbjct: 410 RLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNR 469 Query: 449 QLDTKQPRQ--YFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKK 506 LD + PRQ F+G+LDIAGFEIF NS EQLCIN+TNEKLQQ FNH MFVLEQEEY++ Sbjct: 470 ALD-RSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQR 528 Query: 507 EGIEWTFIDFGMDLAACIELIEKPM---GIFSILEEECMFPKATDTSFKNKLYDQHLGKS 563 EGI WTF+DFG+DL CI+LIE+P G+ ++L+EEC FPKATD SF K+ Q G Sbjct: 529 EGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVA-QEQGGH 587 Query: 564 ANFQKPKVVKGKAEAHFALIHYAGVVDYNITGWLEKNKDPLNETVVGLYQKSAMKTLAQL 623 FQ+P+ ++ +A+ F+++HYAG VDY WL KN DPLN+ V L +S + A++ Sbjct: 588 PKFQRPRHLRDQAD--FSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEI 645 Query: 624 FS------------------------------------GAQTAEGEGAGGGAKKGGKKKG 647 + G E + G GG+ + Sbjct: 646 WKDEHGGFQQFSFLGSFPPSPPGSAERCSSAISPPGVEGIVGLEQVSSLGDGPPGGRPRR 705 Query: 648 SSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEG 707 F+TV L++E+L++LM L +T+P FVRCI+PN K G +E LVL QLRCNGVLEG Sbjct: 706 GMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEG 765 Query: 708 IRICRKGFPSRILYADFKQRYKVLNASAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHT 767 IRICR+GFP+RIL+ +F+QRY++L +AIP+G F+D K+A EK++ ++++D Y+ G + Sbjct: 766 IRICRQGFPNRILFQEFRQRYEILTPNAIPKG-FMDGKQACEKMIQALELDPNLYRVGQS 824 Query: 768 KVFFKAGLLGLLEEMRDDKLAQLITRTQARCRGFLARVEYQRMVERREAIFCIQYNIRSF 827 K+FF+AG+L LEE RD K+ +I QA RG+LAR +Q+ +++ A+ +Q N ++ Sbjct: 825 KIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAAY 884 Query: 828 MNVKHWPWMKLFFKIKPLLKSAETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLL 887 + ++HW W +LF K+KPLL+ ++ + +E QK+++ +S + EL+ ++ L Sbjct: 885 LKLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLE 944 Query: 888 KEKNDLQLQVQAEAEGLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKR 947 +E+ L Q++AEAE A+AEE +L K +LE + E+ R +EEE + ++ +K+ Sbjct: 945 EERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKK 1004 Query: 948 KLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQE 1007 +L+ EL+ ++ E K++ EK TE K+K E++ L++ +KL+KE+K L++ Sbjct: 1005 RLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLED 1064 Query: 1008 AHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKL 1067 + EE+KV +L K ++K E + D+E L +E+K R +LE+ KR+L+G+ Sbjct: 1065 RLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSE 1124 Query: 1068 AQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEE 1127 QE +++ + ++L +L +KE E+ ++ EDE QL K ++E QA + E +E+ Sbjct: 1125 LQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQED 1184 Query: 1128 IEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEA 1187 +E+ER +R KAEKQR DL ELE + LE+ +T+AQ E+ KRE E ++++ LEE Sbjct: 1185 LESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEE 1244 Query: 1188 TLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKA 1247 T HEA LR++H ++ EL EQ++ +R K EK + ++ E+ +L + + ++ A Sbjct: 1245 TRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTA 1304 Query: 1248 KGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQL 1307 + E+ R LE QL E++ + + +R + + R Q E S L+E E+ +L Sbjct: 1305 RQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRL 1364 Query: 1308 SRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRAL 1367 S+ + Q+ + + L+EE +AK AL +++ + LREQ EEE ++ R L Sbjct: 1365 SKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGREL 1424 Query: 1368 SKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRL 1427 A ++++WR + E +A E EEA+++ A+ +A + + LE+ ++RL Sbjct: 1425 QTAQAQLSEWRRRQEEEA-GALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRL 1483 Query: 1428 QNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTEL 1487 Q E++D +D+E+ + L+KKQR FD++LAE K E E ++ E R Sbjct: 1484 QQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARA 1543 Query: 1488 FKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQ 1547 + A EE + E L+R+N+ L+ E+ L + GK +HELE+ + EQ +L+ Sbjct: 1544 LSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLR 1603 Query: 1548 AALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTL 1607 A + E E L E LR+++ + +K++ +R + +DE ++ +R + + + Sbjct: 1604 AQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVER 1663 Query: 1608 DAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDAL 1667 D E + R A+ +KK+EG+L E++ Q+ A + EA++ R Q +K+ +++ Sbjct: 1664 DEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETR 1723 Query: 1668 RSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNT 1727 S+E++ Q E+R L+AE+ L+ L ++R+R+ A+Q+ + ++ V + Sbjct: 1724 TSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKA 1783 Query: 1728 SLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLER 1787 +++ K++LE + Q++ E+E+ + ++ +K + + EL E+ SA E Sbjct: 1784 AILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAES 1843 Query: 1788 MKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLR 1847 ++ +E+ +++L+ RL E + A K I LE+++ + E ++E E + + K +R Sbjct: 1844 GRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVR 1903 Query: 1848 KHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQH 1907 + E+R+KE+ Q EE+R+ +L+D ++K +VK KRQ EEAEE+++ A R+LQ Sbjct: 1904 RAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQR 1963 Query: 1908 ELEEAEERADIAESQVNKLRVKSR 1931 ELE+ E A+ +V LR + R Sbjct: 1964 ELEDVTESAESMNREVTTLRNRLR 1987 Score = 224 bits (572), Expect = 5e-58 Identities = 195/932 (20%), Positives = 421/932 (45%), Gaps = 48/932 (5%) Query: 859 KEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCD------ 912 ++E +K+K L + + EL+E+MV + +L+ Q+ + E L A R + Sbjct: 1108 RQELEKLKRRL---DGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGAR 1164 Query: 913 -QLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVE 971 QL+K+ + +A + E E E E + ++R L +E L+ +++D TL Sbjct: 1165 AQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELED---TLDSTN 1221 Query: 972 KEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVN----TLT 1027 ++ + + +TE L+E + L++ H Q L +L + ++ Sbjct: 1222 AQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWE 1281 Query: 1028 KAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLK 1087 K ++ LE +V +L L + R + E+ +R+LE L+ Q D E + + EKL+ Sbjct: 1282 KTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQ 1341 Query: 1088 KKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSR 1147 + + E+ N+ + + ++ I+L K++ +A++ + +E ++ E ++ + + Sbjct: 1342 RAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEA 1401 Query: 1148 ELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADS-- 1205 E + E+LEE A + +A+ + RR EE EA R+ ++ Sbjct: 1402 EAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEA 1461 Query: 1206 ----VAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQ 1261 +AE E +D L+R +++L++E + M+++ V T+ K + +++ E++ Sbjct: 1462 LTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLA--EEK 1519 Query: 1262 LSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEEL 1321 + L++ EE ++ A+ + + +R L+E++ +L R +A ++E L Sbjct: 1520 AAVLRAVEERERA-----EAEGREREARALSLTRALEEEQEAREELERQNRALRAELEAL 1574 Query: 1322 KRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKY 1381 ++ K+ + L A + + + LR Q E ++ + A + V +T++ Sbjct: 1575 LSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQH 1634 Query: 1382 ETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERT 1441 E D R E EE +++LA++L+ AE + + +++L+ E+E+L + Sbjct: 1635 ERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASA 1694 Query: 1442 NAACAALDKKQRNFDKILAEWKQKCEETHAELEA-------SQKEARSLGTELFKIKNAY 1494 K+ R + E ++ EET E S+K + L E+ +++ Sbjct: 1695 GQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQ--- 1751 Query: 1495 EESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAE 1554 ++L R + QQ+ ++ +++A G + + K+Q+E +L+ LEE + Sbjct: 1752 ----EELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQ 1807 Query: 1555 ASLEHEEGKILRIQLELNQVKSEV--DRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIR 1612 ++ E + ++ L++ + +E+ +R + K E Q I+ + DA R Sbjct: 1808 SNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGAR 1867 Query: 1613 SRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQED 1672 +R+ +E L + E QL R + + R + LK+ + +++ R + Sbjct: 1868 ARHKMTIAA--LESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQ 1925 Query: 1673 LKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINT 1732 L++QL R L+ ++EE + + R+ ++EL D +E + ++ + T+L N Sbjct: 1926 LRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNR 1985 Query: 1733 KKKLETDISQMQGEMEDILQEARNAEEKAKKA 1764 ++ + L+E ++E+A++A Sbjct: 1986 LRRGPLTFTTRTVRQVFRLEEGVASDEEAEEA 2017 Score = 171 bits (434), Expect = 5e-42 Identities = 178/881 (20%), Positives = 381/881 (43%), Gaps = 83/881 (9%) Query: 1099 KIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEE 1158 +++ Q L Q +++ ELQ R+ +LEEE RA A+ + ++L E EE RL Sbjct: 918 ELQKVQELQQQSAREVGELQGRVAQLEEE----RARLAEQLRAEAELCAEAEETRGRLAA 973 Query: 1159 AGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQR 1218 + + R E ++ R ++ T +K+ + EL ++ + Sbjct: 974 RKQELELVVSELEARVGEEEECSRQMQ-----------TEKKRLQQHIQELEAHLEAEEG 1022 Query: 1219 VKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLIND 1278 +QKL+ EK + ++ ++ + L K + LED+L+E S+ E++ + Sbjct: 1023 ARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKS 1082 Query: 1279 LTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHA 1338 L R + + + +L ++E +L + K+ + EL+ Q+ E+ + L Sbjct: 1083 LNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQ 1142 Query: 1339 LQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKK 1398 L + + E+E ++A+L ++L +A +A+ + E++ + RT+ E+ ++ Sbjct: 1143 LGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKA-EKQRRD 1201 Query: 1399 LAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVER-TNAACAALDKKQRNFDK 1457 L + L+A +E + ++ + + + EV +L +E T AA+ + ++ + Sbjct: 1202 LGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQ 1261 Query: 1458 ILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISD 1517 L E ++ E+ A +K +L E+ +++ L L+T ++E + ++ Sbjct: 1262 ALGELAEQLEQARRGKGAWEKTRLALEAEVSELR----AELSSLQTARQEGEQRRRR--- 1314 Query: 1518 LTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSE 1577 L Q+ E R + E+ + + ++ QA LE +L E K +R+ EL+ +++ Sbjct: 1315 LELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQ 1374 Query: 1578 VDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNH 1637 + Q L E R++ + ME + + QL Sbjct: 1375 L----------------------HDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEE 1412 Query: 1638 ANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRAT 1697 A R + Q L + + ++ + E +E R A L + E T Sbjct: 1413 EAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTET 1472 Query: 1698 LEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNA 1757 +++ ER R+ +QEL DA+ ++ ++L ++K + +++ + + ++E A Sbjct: 1473 VDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERA 1532 Query: 1758 EEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAE------QLAL 1811 E + ++ A + L++EQ+ LER + + ++ L D+ + A Sbjct: 1533 EAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERAC 1592 Query: 1812 KGGKKQIQKLEARVRELEGEV---ESEQKRNAEAVKGLR-KHER---------------- 1851 + ++ L A+V ELE E+ E + R V+ L+ +HER Sbjct: 1593 RVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQL 1652 Query: 1852 --RVKELTYQTEEDRKNIL-------RLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKF 1902 ++++ + +E+RK +L+ +++L+A++ S + EEA +Q A+ Sbjct: 1653 AKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQM 1712 Query: 1903 RKLQHELEEAEERAD--IAESQVNKLRVKSREVHTKVISEE 1941 ++L E+EE + ++++ ++ R+K E + EE Sbjct: 1713 KELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEE 1753 Score = 117 bits (292), Expect = 1e-25 Identities = 130/642 (20%), Positives = 262/642 (40%), Gaps = 49/642 (7%) Query: 1339 LQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKK 1398 LQ+ + ++E ++ ELQ +++ E A+ + +A + E EE + + Sbjct: 912 LQARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEA-ELCAEAEETRGR 970 Query: 1399 LAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALD--KKQRNFD 1456 LA R Q E V + A+ E+ +++Q E + L ++ A A + +++ + Sbjct: 971 LAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLE 1030 Query: 1457 KILAEWKQKCEETHAELEASQ-----KEARSLGTELFKIKNAYEESLDQLETLKRENKNL 1511 K+ E K K E L Q KE + L L + + E +++++L + Sbjct: 1031 KVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKY 1090 Query: 1512 QQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLEL 1571 + I+D+ +++ + K ELEK+K++++ E ELQ + E + E ++ R + EL Sbjct: 1091 EATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEEL 1150 Query: 1572 NQVKS-----------------EVDRKIAEKDEEID----------QLKRNHIRIVESMQ 1604 + E +AE E+++ + +R+ +E+++ Sbjct: 1151 QAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALR 1210 Query: 1605 STLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLD 1664 L+ + S N L+ K E ++ E++ L R+ A++ R G L Sbjct: 1211 GELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQA------LG 1264 Query: 1665 DALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHT 1724 + E + E+ L+AE+ ELRA L + +R+ EQ ++Q + Sbjct: 1265 ELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQG 1324 Query: 1725 QNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAH 1784 + + + + + Q E+E++ AE K + + + +L Q+ Sbjct: 1325 RAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQE 1384 Query: 1785 LERMK-------KNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQK 1837 R K + ME L+ +L+E E A + +++Q +A++ E E E Sbjct: 1385 ETRAKLALGSRVRAMEAEAAGLREQLEE-EAAARERAGRELQTAQAQLSEWRRRQEEEAG 1443 Query: 1838 RNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNT 1897 + R+ R + LT + E + + RL+ +LQ ++ E+ + +T Sbjct: 1444 ALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVST 1503 Query: 1898 NLAKFRKLQHELEEAEERADIAESQVNKLRVKSREVHTKVIS 1939 K RK L E + A + + + RE + +S Sbjct: 1504 LEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALS 1545 >gi|153945715 myosin VC [Homo sapiens] Length = 1742 Score = 608 bits (1569), Expect = e-173 Identities = 454/1440 (31%), Positives = 718/1440 (49%), Gaps = 107/1440 (7%) Query: 38 VFVAEPKESFVKGTIQS--REGGKVT-VKTEGGATL--TVKDDQVFPM-NPPKYDKIEDM 91 V++ +P+E + I R G KV + E G L +V + + P+ NP D+ Sbjct: 13 VWIPDPEEVWKSAEIAKDYRVGDKVLRLLLEDGTELDYSVNPESLPPLRNPDILVGENDL 72 Query: 92 AMMTHLHEPAVLYNLKERYA-AWMIYTYSGLFCVTVNPYKWLPVYKPEVVTAYRGKKRQE 150 +++LHEPAVL+NL+ R+A + +IYTYSG+ V +NPYK LP+Y ++ AY G+ + Sbjct: 73 TALSYLHEPAVLHNLRIRFAESKLIYTYSGIILVAMNPYKQLPIYGDAIIHAYSGQNMGD 132 Query: 151 APPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKEEI 210 PHIF++++ AY+ M + NQSI+++GESGAGKTV+ + ++YFAT++ +G Sbjct: 133 MDPHIFAVAEEAYKQMARNNRNQSIIVSGESGAGKTVSARYAMRYFATVSKSGSNAH--- 189 Query: 211 TSGKIQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYL 270 +ED+++++NP+ EA GNAKT RNDNSSRFGK+ I F ++ A++ TYL Sbjct: 190 --------VEDKVLASNPITEAVGNAKTTRNDNSSRFGKYTEISFDEQNQIIGANMSTYL 241 Query: 271 LEKSRVVFQLKAERSYHIFYQI-TSNKKPELIEMLLITTNPYDYPFVSQGEISVASIDDQ 329 LEKSRVVFQ + ER+YHIFYQ+ S ++ E + L + ++Y + G + ++D+ Sbjct: 242 LEKSRVVFQSENERNYHIFYQLCASAQQSEFKHLKLGSAEEFNYTRMG-GNTVIEGVNDR 300 Query: 330 EELMATDSAIDILGFTNEEKVSIYKLTGAVMHYGNLKFKQKQREEQAEPDGTEVADKAAY 389 E++ T +LGF + ++ ++K+ A++H GN++ E + + Sbjct: 301 AEMVETQKTFTLLGFKEDFQMDVFKILAAILHLGNVQITAVGNERSSVSEDDSHLKVFCE 360 Query: 390 LQSLNSADLLKALCYPRVKVGNEYVTKGQTVEQVSNAVGALAKAVYEKMFLWMVARINQQ 449 L L S + + LC ++ +E V K T Q NA ALAK +Y +F ++V RINQ Sbjct: 361 LLGLESGRVAQWLCNRKIVTSSETVVKPMTRPQAVNARDALAKKIYAHLFDFIVERINQA 420 Query: 450 LDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGI 509 L + FIGVLDI GFE FD NS EQ CIN+ NEKLQQ FN H+F LEQEEY KE I Sbjct: 421 LQFSGKQHTFIGVLDIYGFETFDVNSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEDI 480 Query: 510 EWTFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLYDQHLGKSANFQKP 569 WT IDF D I+LIE MGI +L+EEC+ P TD ++ KLY+ + ++ F+KP Sbjct: 481 PWTLIDF-YDNQPVIDLIEAKMGILELLDEECLLPHGTDENWLQKLYNNFVNRNPLFEKP 539 Query: 570 KVVKGKAEAHFALIHYAGVVDYNITGWLEKNKDPLNETVVGLYQKSAMKTLAQLFSGAQT 629 ++ + F + H+A V+Y G+LEKN+D + + +V + + S A F T Sbjct: 540 RM----SNTSFVIQHFADKVEYKCEGFLEKNRDTVYDMLVEILRASKFHLCANFFQENPT 595 Query: 630 AEGEGAG----GGAKKGGKKKGSSFQ-TVSALFRENLNKLMTNLRSTHPHFVRCIIPNET 684 AK+ K F+ TV + FR +L LM L +T PH+VRCI PN+ Sbjct: 596 PPSPFGSMITVKSAKQVIKPNSKHFRTTVGSKFRSSLYLLMETLNATTPHYVRCIKPNDE 655 Query: 685 KTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQFIDS 744 K P + + ++ QLR GVLE IRI + +PSR Y +F RY +L E F D Sbjct: 656 KLPFEFDSKRIVQQLRACGVLETIRISAQSYPSRWTYIEFYSRYGILMTK--QELSFSDK 713 Query: 745 KKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDDKLAQLITRTQARCRGFLAR 804 K+ + +L + D QY+FG TK+FF+AG + LE++R DKL Q Q RG+L R Sbjct: 714 KEVCKVVLHRLIQDSNQYQFGKTKIFFRAGQVAYLEKLRLDKLRQSCVMVQKHMRGWLQR 773 Query: 805 VEYQRMVERREAIFCIQYNIRSFMNVK--------HWPWMKLFFKIK---PLLKSAETEK 853 ++ R ERR A+ QY R V+ W + + L++S Sbjct: 774 KKFLR--ERRAALIIQQY-FRGQQTVRKAITAVALKEAWAAIIIQKHCRGYLVRSLYQLI 830 Query: 854 EMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCDQ 913 MAT+ Q RK LEE + LQ A A LA + + Sbjct: 831 RMATI--TMQAYSRGFLARRRYRKMLEEHKAVI--------LQKYARA-WLARRRFQSIR 879 Query: 914 LIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKE 973 IQL +++ + ++ ED+ + N L K L + + I LE L K Sbjct: 880 RFVLNIQLTYRVQRLQKKLEDQNKENHGLVEKLTSLAALRAGDVEKIQKLEAELEKAATH 939 Query: 974 KHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKL 1033 + E K K + ++E +AKL K L+ +Q LQ + +++ K K+ Sbjct: 940 RRNYEEKGKRYRD---AVEEKLAKLQKHNSELETQKEQIQLKLQEKTEEL------KEKM 990 Query: 1034 EQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEI 1093 + L +++E++ RM LE K + D E + Q L E++K + E Sbjct: 991 DNLTKQLFDDVQKEERQRMLLE----------KSFELKTQDYEKQIQSLKEEIKALKDEK 1040 Query: 1094 SNLQSKIEDEQALGIQLQKKIKELQAR---IEELEEEIEAERASRAKAEK----QRSDLS 1146 LQ +E E L+ ++ L + I E E+EIE +A + EK Q+ ++ Sbjct: 1041 MQLQHLVEGEHVTSDGLKAEVARLSKQVKTISEFEKEIELLQAQKIDVEKHVQSQKREMR 1100 Query: 1147 RELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSV 1206 ++ EI+++L E S IE + R + DLE E A K A V Sbjct: 1101 EKMSEITKQLLE-----SYDIEDVRSRLSV-----EDLEHLNEDGELWFAYEGLKKATRV 1150 Query: 1207 AELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELK 1266 E + Q K EKE + ++ L+ + + K + ++ +++ L Sbjct: 1151 LE-----SHFQSQKDCYEKEIEALNFKVVHLSQEINHLQKLFREENDINESIRHEVTRLT 1205 Query: 1267 SKE---EEQQRLINDLTAQRGRLQTESGEFSRQLDEK-EALVSQLSRGKQAFTQQIEELK 1322 S+ + ++ I++L Q+ L+ E + ++ K E L +QL R ++ Q + L+ Sbjct: 1206 SENMMIPDFKQQISELEKQKQDLEIRLNEQAEKMKGKLEELSNQLHRSQEEEGTQRKALE 1265 Query: 1323 RQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYE 1382 Q E K K L +Q + D L++Q+E E E K ++ S+ E + E Sbjct: 1266 AQNEIHTKEKEKLIDKIQEMQEASDHLKKQFETESEVKCNFRQEASRLTLENRD--LEEE 1323 Query: 1383 TDAIQRT-EELEEAKKKLAQRLQAAEEHVEAVNAK--CASLEKTKQRLQNEVEDLMLDVE 1439 D R ++L++ K L++ + A + + K L+ ++ +++L+LD++ Sbjct: 1324 LDMKDRVIKKLQDQVKTLSKTIGKANDVHSSSGPKEYLGMLQYKREDEAKLIQNLILDLK 1383 Score = 77.8 bits (190), Expect = 1e-13 Identities = 99/525 (18%), Positives = 222/525 (42%), Gaps = 45/525 (8%) Query: 1315 TQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEV 1374 T +++ L+++LE++ K + L L S L E+ Q+ +AEL++A Sbjct: 888 TYRVQRLQKKLEDQNKENHGLVEKLTSL---AALRAGDVEKIQKLEAELEKA-------- 936 Query: 1375 AQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCAS-LEKTKQRLQNEVED 1433 A R YE + + +EE KL + E E + K E+ K+++ N + Sbjct: 937 ATHRRNYEEKGKRYRDAVEEKLAKLQKHNSELETQKEQIQLKLQEKTEELKEKMDNLTKQ 996 Query: 1434 LMLDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNA 1493 L DV++ L+K ++ K ++ ++++ ++E ++L E ++++ Sbjct: 997 LFDDVQKEERQRMLLEKS----------FELKTQDYEKQIQSLKEEIKALKDEKMQLQHL 1046 Query: 1494 YEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEA 1553 E + LK E L +++ K I E EK + ++ +K +++ ++ Sbjct: 1047 VEGEHVTSDGLKAEVARLSKQV-----------KTISEFEKEIELLQAQKIDVEKHVQSQ 1095 Query: 1554 EASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQST--LDAEI 1611 + + + +I + LE ++ R E E +++ ++T L++ Sbjct: 1096 KREMREKMSEITKQLLESYDIEDVRSRLSVEDLEHLNEDGELWFAYEGLKKATRVLESHF 1155 Query: 1612 RSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQE 1671 +S+ D +K++E LN + L+ + R + ++ L Sbjct: 1156 QSQKDCY--EKEIEA-LNFKVVHLSQEINHLQKLFREENDINESIRHEVTRLTSENMMIP 1212 Query: 1672 DLKEQLAMVERRANLLQAEI----EELRATLEQTERSRKIAEQELLDASERVQLLHTQNT 1727 D K+Q++ +E++ L+ + E+++ LE+ +++E + ++R + L QN Sbjct: 1213 DFKQQISELEKQKQDLEIRLNEQAEKMKGKLEELSNQLHRSQEE--EGTQR-KALEAQNE 1269 Query: 1728 SLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLER 1787 K+KL I +MQ + + ++ E +A+ + E + ++ +R Sbjct: 1270 IHTKEKEKLIDKIQEMQEASDHLKKQFETESEVKCNFRQEASRLTLENRDLEEELDMKDR 1329 Query: 1788 MKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEV 1832 + K ++ VK L + +A + G K+ + RE E ++ Sbjct: 1330 VIKKLQDQVKTLSKTIGKANDVHSSSGPKEYLGMLQYKREDEAKL 1374 Score = 70.5 bits (171), Expect = 2e-11 Identities = 97/511 (18%), Positives = 216/511 (42%), Gaps = 57/511 (11%) Query: 1452 QRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAY--EESLDQLETLKRENK 1509 +R + K+L E K + +A +++ +S+ + I+ Y + +LE +EN Sbjct: 847 RRRYRKMLEEHKAVILQKYARAWLARRRFQSIRRFVLNIQLTYRVQRLQKKLEDQNKENH 906 Query: 1510 NLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQL 1569 L ++++ L A ++I +LE ++ + + + ++E + K+ + Sbjct: 907 GLVEKLTSLAALRAGDVEKIQKLEAELEKAATHRRNYEEKGKRYRDAVEEKLAKLQKHNS 966 Query: 1570 ELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLN 1629 EL K ++ K+ EK EE+ + N + + + + E R R + L+K E Sbjct: 967 ELETQKEQIQLKLQEKTEELKEKMDN---LTKQLFDDVQKEERQR---MLLEKSFELKTQ 1020 Query: 1630 EMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQ----EDLKEQLAMVERRAN 1685 + E Q+ ++ + LKD ++ L + + + LK ++A + ++ Sbjct: 1021 DYEKQI-----------QSLKEEIKALKDEKMQLQHLVEGEHVTSDGLKAEVARLSKQVK 1069 Query: 1686 LL---QAEIEELRATLEQTERSRKIAEQELLDASERV--QLLHTQNTSLINTKKKLETDI 1740 + + EIE L+A E+ + ++E+ + + QLL + + + ++ +E D+ Sbjct: 1070 TISEFEKEIELLQAQKIDVEKHVQSQKREMREKMSEITKQLLESYDIEDVRSRLSVE-DL 1128 Query: 1741 SQMQGE----------------MEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAH 1784 + + +E Q ++ EK +A+ + L +E + Sbjct: 1129 EHLNEDGELWFAYEGLKKATRVLESHFQSQKDCYEKEIEALNFKVV---HLSQEINHLQK 1185 Query: 1785 LERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVK 1844 L R + ++ ++++ RL +E + + K+QI +LE + ++LE + + ++ ++ Sbjct: 1186 LFREENDINESIRHEVTRLT-SENMMIPDFKQQISELEKQKQDLEIRLNEQAEKMKGKLE 1244 Query: 1845 GLRKHERRVKE--------LTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSN 1896 L R +E L Q E K +L D + ++Q K+Q E E Sbjct: 1245 ELSNQLHRSQEEEGTQRKALEAQNEIHTKEKEKLIDKIQEMQEASDHLKKQFETESEVKC 1304 Query: 1897 TNLAKFRKLQHELEEAEERADIAESQVNKLR 1927 + +L E + EE D+ + + KL+ Sbjct: 1305 NFRQEASRLTLENRDLEEELDMKDRVIKKLQ 1335 Score = 34.7 bits (78), Expect = 0.93 Identities = 27/118 (22%), Positives = 55/118 (46%), Gaps = 13/118 (11%) Query: 1820 KLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQA 1879 +L RV+ L+ ++E + K N V+ ++ L D + I +L+ ++K Sbjct: 886 QLTYRVQRLQKKLEDQNKENHGLVE-------KLTSLAALRAGDVEKIQKLEAELEKAAT 938 Query: 1880 KVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAESQVNKLRVKSREVHTKV 1937 ++Y+ + + + LAK +K ELE +E+ + KL+ K+ E+ K+ Sbjct: 939 HRRNYEEKGKRYRDAVEEKLAKLQKHNSELETQKEQIQL------KLQEKTEELKEKM 990 >gi|215982794 myosin VA isoform 2 [Homo sapiens] Length = 1828 Score = 597 bits (1539), Expect = e-170 Identities = 456/1569 (29%), Positives = 758/1569 (48%), Gaps = 208/1569 (13%) Query: 90 DMAMMTHLHEPAVLYNLKERYA-AWMIYTYSGLFCVTVNPYKWLPVYKPEVVTAYRGKKR 148 D+ +++LHEPAVL+NL+ R+ + +IYTY G+ V +NPY+ LP+Y +++ AY G+ Sbjct: 73 DLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAYSGQNM 132 Query: 149 QEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKE 208 + PHIF++++ AY+ M D NQSI+++GESGAGKTV+ K ++YFAT++ + Sbjct: 133 GDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGSAS---- 188 Query: 209 EITSGKIQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIET 268 + +E++++++NP++E+ GNAKT RNDNSSRFGK+I I F ++ A++ T Sbjct: 189 -------EANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMRT 241 Query: 269 YLLEKSRVVFQLKAERSYHIFYQITSNKKPELIEMLLITTNPYDYPFVSQGEISVAS-ID 327 YLLEKSRVVFQ + ER+YHIFYQ+ ++ K +ML + N ++ + QG V +D Sbjct: 242 YLLEKSRVVFQAEEERNYHIFYQLCASAKLPEFKMLRLG-NADNFNYTKQGGSPVIEGVD 300 Query: 328 DQEELMATDSAIDILGFTNEEKVSIYKLTGAVMHYGNLKFKQKQREEQAEPDGTEVADKA 387 D +E+ T A +LG + ++ I+++ ++H GN+ F + + P E Sbjct: 301 DAKEMAHTRQACTLLGISESHQMGIFRILAGILHLGNVGFTSRDADSCTIPPKHEPLCIF 360 Query: 388 AYLQSLNSADLLKALCYPRVKVGNEYVTKGQTVEQVSNAVGALAKAVYEKMFLWMVARIN 447 L ++ ++ LC+ ++ E K + Q +NA ALAK +Y K+F W+V +N Sbjct: 361 CDLMGVDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVDNVN 420 Query: 448 QQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKE 507 Q L + + FIGVLDI GFE F+ NS EQ CIN+ NEKLQQ FN H+F LEQEEY KE Sbjct: 421 QALHSAVKQHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKE 480 Query: 508 GIEWTFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLYDQHLGKSANFQ 567 I WT IDF D CI LIE +GI +L+EEC PK TD ++ KLY+ HL K A F+ Sbjct: 481 QIPWTLIDF-YDNQPCINLIESKLGILDLLDEECKMPKGTDDTWAQKLYNTHLNKCALFE 539 Query: 568 KPKVVKGKAEAHFALIHYAGVVDYNITGWLEKNKDPLNETVVGLYQKSAMKTLAQLF--- 624 KP++ + F + H+A V+Y G+LEKNKD + E + + + S K L +LF Sbjct: 540 KPRL----SNKAFIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLPELFQDD 595 Query: 625 -----------SGAQTAEGEGAGGGAKKGGKKKGSSFQTVSALFRENLNKLMTNLRSTHP 673 SG A + G+ +TV FR +L+ LM L +T P Sbjct: 596 EKAISPTSATSSGRTPLTRTPAKPTKGRPGQMAKEHKKTVGHQFRNSLHLLMETLNATTP 655 Query: 674 HFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNA 733 H+VRCI PN+ K P + + + QLR GVLE IRI GFPSR Y +F RY+VL Sbjct: 656 HYVRCIKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRVLMK 715 Query: 734 SAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDDKLAQLITR 793 + D K+ + +L + +D +Y+FG TK+FF+AG + LE++R DKL R Sbjct: 716 Q---KDVLSDRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKLRADKLRAACIR 772 Query: 794 TQARCRGFLARVEYQRMVERREAIFCIQYNIRSFM---------NVKHWPWMKLFFKIKP 844 Q RG+L R +Y RM R+A +Q +R + K ++ ++++ Sbjct: 773 IQKTIRGWLLRKKYLRM---RKAAITMQRYVRGYQARCYAKFLRRTKAATIIQKYWRMYV 829 Query: 845 LLKSAETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKE----------KNDL- 893 + + + + + + + ++ LA++ ++ E K V + K K + Sbjct: 830 VRRRYKIRRAATIVLQSY--LRGFLARNRYRKILREHKAVIIQKRVRGWLARTHYKRSMH 887 Query: 894 ----------QLQVQAEAEGLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELT 943 ++ + E + L ++ K I +E KI ++ + +++ + L Sbjct: 888 AIIYLQCCFRRMMAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLV 947 Query: 944 AKKRKLE----DECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLT 999 K LE E +L+ D++ L+L+ E+E +V +L EE+A L + + + Sbjct: 948 EKLTNLEGIYNSETEKLRSDLERLQLS----EEEAKVATGRVLSLQEEIAKLRKDLEQTR 1003 Query: 1000 KEKKALQE---AHQQTLDDLQAEEDKVNTLTKAK-----IKLEQQVDDLEGSLEQE---- 1047 EKK ++E ++Q + L + + NTL K + ++ QQ ++ ++E++ Sbjct: 1004 SEKKCIEEHADRYKQETEQLVSNLKEENTLLKQEKEALNHRIVQQAKEMTETMEKKLVEE 1063 Query: 1048 -KKLRMDL--ERAK-RKLEGDLKLAQESIMDIENE-------------KQQLDEKLKKKE 1090 K+L +DL ER + + L + +E D++ E + + E Sbjct: 1064 TKQLELDLNDERLRYQNLLNEFSRLEERYDDLKEEMTLMVHVPKPGHKRTDSTHSSNESE 1123 Query: 1091 FEISNLQSKIED---------------EQALGIQLQKKIKELQARIEELEEEIEAER--- 1132 + S+ +++ED + +L ++LQK++ EL+ + +++E++ + Sbjct: 1124 YIFSSEIAEMEDIPSRTEEPSEKKVPLDMSLFLKLQKRVTELEQEKQVMQDELDRKEEQV 1183 Query: 1133 -ASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDL-EEATLQ 1190 S+AK E++ ELE S + +E NKK + E ++R+ L E++ + Sbjct: 1184 LRSKAKEEERPQIRGAELEYESLKRQELESE-------NKKLKNELNELRKALSEKSAPE 1236 Query: 1191 HEATAATLRKKHADSVAELGEQID---------NLQRVKQKLEKEKSEMKMEIDDLASNV 1241 A A + + + + E++D Q V QK + + K + D + Sbjct: 1237 VTAPGAPAYRVLMEQLTSVSEELDVRKEEVLILRSQLVSQKEAIQPKDDKNTMTDSTILL 1296 Query: 1242 ETVSKAKG---------NLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGE 1292 E V K K L++ R LE QL K E N+ A RG +Q+ E Sbjct: 1297 EDVQKMKDKGEIAQAYIGLKETNRLLESQLQSQKRSHE------NEAEALRGEIQSLKEE 1350 Query: 1293 FSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQ 1352 +RQ QQ+ QL E + + +L H + ++ L EQ Sbjct: 1351 NNRQ-------------------QQLLAQNLQLPPEARIEASLQHEITRLTNENLDLMEQ 1391 Query: 1353 YEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEA 1412 E++ ++ +L++ L ++ ELE + + Q +E + Sbjct: 1392 LEKQDKTVRKLKKQLKVFAKKIG---------------ELEVGQMENISPGQIIDEPIRP 1436 Query: 1413 VNAK------CASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKC 1466 VN LE K+ Q V++L+L+++ A N L + Sbjct: 1437 VNIPRKEKDFQGMLEYKKEDEQKLVKNLILELKPRGVAV--------NLIPGLPAYILFM 1488 Query: 1467 EETHAELEASQKEARSLGTE-LFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEG 1525 HA+ ++ RSL T + IK ++ D ET+ N + + L + E Sbjct: 1489 CVRHADYLNDDQKVRSLLTSTINSIKKVLKKRGDDFETVSFWLSNTCRFLHCLKQYSGEE 1548 Query: 1526 GKRIHELEK 1534 G H + Sbjct: 1549 GFMKHNTSR 1557 Score = 57.4 bits (137), Expect = 1e-07 Identities = 106/495 (21%), Positives = 215/495 (43%), Gaps = 93/495 (18%) Query: 1472 ELEASQKEARSLGTELFKIKNAYEESLDQLET-LKRENKNLQQEISDLTEQIAEGGKRIH 1530 EL+ + EARS+ K+ E + QL+ + +NK+ + + LT G Sbjct: 904 ELKKLKIEARSV-ERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNL---EGIYNS 959 Query: 1531 ELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEK---DE 1587 E EK++ +E+ LQ + EEA+ + G++L +Q E+ +++ ++++ +EK +E Sbjct: 960 ETEKLRSDLER----LQLSEEEAKVAT----GRVLSLQEEIAKLRKDLEQTRSEKKCIEE 1011 Query: 1588 EIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALR 1647 D+ K+ ++V ++ + + LK++ E LNH A+ + Sbjct: 1012 HADRYKQETEQLVSNL----------KEENTLLKQEKEA--------LNHRIVQQAKEMT 1053 Query: 1648 NYRNTQGILKDTQIHLD---DALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERS 1704 + + + Q+ LD + LR Q L E + ER +L EE+ + + Sbjct: 1054 ETMEKKLVEETKQLELDLNDERLRYQNLLNEFSRLEERYDDLK----EEMTLMVHVPKPG 1109 Query: 1705 RKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKA 1764 K R H+ N S E S EMEDI +R E KK Sbjct: 1110 HK-----------RTDSTHSSNES--------EYIFSSEIAEMEDI--PSRTEEPSEKKV 1148 Query: 1765 ITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEAR 1824 D ++ + L++ +EQ + +Q LD E+ L+ K+ ++ + R Sbjct: 1149 PLDMSLFLK-----------LQKRVTELEQEKQVMQDELDRKEEQVLRSKAKEEERPQIR 1197 Query: 1825 VRELE------GEVESEQKRNAEAVKGLRK--HERRVKELTYQTEEDRKNIL-RLQDLVD 1875 ELE E+ESE K+ + LRK E+ E+T + ++ +L + + Sbjct: 1198 GAELEYESLKRQELESENKKLKNELNELRKALSEKSAPEVTAPGAPAYRVLMEQLTSVSE 1257 Query: 1876 KLQAKVKSY---------KRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAESQVNKL 1926 +L + + +++A + ++ NT + L ++++ +++ +IA++ + L Sbjct: 1258 ELDVRKEEVLILRSQLVSQKEAIQPKDDKNT-MTDSTILLEDVQKMKDKGEIAQAYIG-L 1315 Query: 1927 RVKSREVHTKVISEE 1941 + +R + +++ S++ Sbjct: 1316 KETNRLLESQLQSQK 1330 >gi|215982791 myosin VA isoform 1 [Homo sapiens] Length = 1855 Score = 594 bits (1532), Expect = e-169 Identities = 435/1453 (29%), Positives = 731/1453 (50%), Gaps = 164/1453 (11%) Query: 90 DMAMMTHLHEPAVLYNLKERYA-AWMIYTYSGLFCVTVNPYKWLPVYKPEVVTAYRGKKR 148 D+ +++LHEPAVL+NL+ R+ + +IYTY G+ V +NPY+ LP+Y +++ AY G+ Sbjct: 73 DLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAYSGQNM 132 Query: 149 QEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKE 208 + PHIF++++ AY+ M D NQSI+++GESGAGKTV+ K ++YFAT++ + Sbjct: 133 GDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGSAS---- 188 Query: 209 EITSGKIQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIET 268 + +E++++++NP++E+ GNAKT RNDNSSRFGK+I I F ++ A++ T Sbjct: 189 -------EANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMRT 241 Query: 269 YLLEKSRVVFQLKAERSYHIFYQITSNKKPELIEMLLITTNPYDYPFVSQGEISVAS-ID 327 YLLEKSRVVFQ + ER+YHIFYQ+ ++ K +ML + N ++ + QG V +D Sbjct: 242 YLLEKSRVVFQAEEERNYHIFYQLCASAKLPEFKMLRLG-NADNFNYTKQGGSPVIEGVD 300 Query: 328 DQEELMATDSAIDILGFTNEEKVSIYKLTGAVMHYGNLKFKQKQREEQAEPDGTEVADKA 387 D +E+ T A +LG + ++ I+++ ++H GN+ F + + P E Sbjct: 301 DAKEMAHTRQACTLLGISESHQMGIFRILAGILHLGNVGFTSRDADSCTIPPKHEPLCIF 360 Query: 388 AYLQSLNSADLLKALCYPRVKVGNEYVTKGQTVEQVSNAVGALAKAVYEKMFLWMVARIN 447 L ++ ++ LC+ ++ E K + Q +NA ALAK +Y K+F W+V +N Sbjct: 361 CDLMGVDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVDNVN 420 Query: 448 QQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKE 507 Q L + + FIGVLDI GFE F+ NS EQ CIN+ NEKLQQ FN H+F LEQEEY KE Sbjct: 421 QALHSAVKQHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKE 480 Query: 508 GIEWTFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLYDQHLGKSANFQ 567 I WT IDF D CI LIE +GI +L+EEC PK TD ++ KLY+ HL K A F+ Sbjct: 481 QIPWTLIDF-YDNQPCINLIESKLGILDLLDEECKMPKGTDDTWAQKLYNTHLNKCALFE 539 Query: 568 KPKVVKGKAEAHFALIHYAGVVDYNITGWLEKNKDPLNETVVGLYQKSAMKTLAQLF--- 624 KP++ + F + H+A V+Y G+LEKNKD + E + + + S K L +LF Sbjct: 540 KPRL----SNKAFIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLPELFQDD 595 Query: 625 -----------SGAQTAEGEGAGGGAKKGGKKKGSSFQTVSALFRENLNKLMTNLRSTHP 673 SG A + G+ +TV FR +L+ LM L +T P Sbjct: 596 EKAISPTSATSSGRTPLTRTPAKPTKGRPGQMAKEHKKTVGHQFRNSLHLLMETLNATTP 655 Query: 674 HFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNA 733 H+VRCI PN+ K P + + + QLR GVLE IRI GFPSR Y +F RY+VL Sbjct: 656 HYVRCIKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRVLMK 715 Query: 734 SAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDDKLAQLITR 793 + D K+ + +L + +D +Y+FG TK+FF+AG + LE++R DKL R Sbjct: 716 Q---KDVLSDRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKLRADKLRAACIR 772 Query: 794 TQARCRGFLARVEYQRMVERREAIFCIQYNIRSFM---------NVKHWPWMKLFFKIKP 844 Q RG+L R +Y RM R+A +Q +R + K ++ ++++ Sbjct: 773 IQKTIRGWLLRKKYLRM---RKAAITMQRYVRGYQARCYAKFLRRTKAATIIQKYWRMYV 829 Query: 845 LLKSAETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKE----------KNDL- 893 + + + + + + + ++ LA++ ++ E K V + K K + Sbjct: 830 VRRRYKIRRAATIVLQSY--LRGFLARNRYRKILREHKAVIIQKRVRGWLARTHYKRSMH 887 Query: 894 ----------QLQVQAEAEGLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELT 943 ++ + E + L ++ K I +E KI ++ + +++ + L Sbjct: 888 AIIYLQCCFRRMMAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLV 947 Query: 944 AKKRKLE----DECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLT 999 K LE E +L+ D++ L+L+ E+E +V +L EE+A L + + + Sbjct: 948 EKLTNLEGIYNSETEKLRSDLERLQLS----EEEAKVATGRVLSLQEEIAKLRKDLEQTR 1003 Query: 1000 KEKKALQE---AHQQTLDDLQAEEDKVNTLTKAK-----IKLEQQVDDLEGSLEQE---- 1047 EKK ++E ++Q + L + + NTL K + ++ QQ ++ ++E++ Sbjct: 1004 SEKKCIEEHADRYKQETEQLVSNLKEENTLLKQEKEALNHRIVQQAKEMTETMEKKLVEE 1063 Query: 1048 -KKLRMDL--ERAK-RKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDE 1103 K+L +DL ER + + L + +E D++ E + K + S E E Sbjct: 1064 TKQLELDLNDERLRYQNLLNEFSRLEERYDDLKEEMTLMVHVPKPGHKRTDSTHSSNESE 1123 Query: 1104 QALGIQLQKKIKELQARIEE-LEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGA 1162 ++ +++++ +R EE E+++ + + K +K+ ++L +E + + + L+ Sbjct: 1124 YIFSSEI-AEMEDIPSRTEEPSEKKVPLDMSLFLKLQKRVTELEQEKQVMQDELDR---- 1178 Query: 1163 TSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQK 1222 Q+ +K +E E R + A L++E+ +Q+ Sbjct: 1179 KEEQVLRSKAKEEE----RPQIRGAELEYESLK------------------------RQE 1210 Query: 1223 LEKEKSEMKMEIDDL--ASNVETVSKAKGNLEKMCRTLEDQLS----ELKSKEEEQQRLI 1276 LE E ++K E+++L A + ++ + R L +QL+ EL ++EE L Sbjct: 1211 LESENKKLKNELNELRKALSEKSAPEVTAPGAPAYRVLMEQLTSVSEELDVRKEEVLILR 1270 Query: 1277 NDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALA 1336 + L +Q+ +Q + D+K + + ++++K + E +A L Sbjct: 1271 SQLVSQKEAIQPK--------DDKNTMTD-----STILLEDVQKMKDK-GEIAQAYIGLK 1316 Query: 1337 HALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAK 1396 +SS D L E E + L++A +++ + +E +A E++ K Sbjct: 1317 ETNRSSALDYHELNEDGELWLVYEG-LKQANRLLESQLQSQKRSHENEAEALRGEIQSLK 1375 Query: 1397 KK-------LAQRLQ-AAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAAL 1448 ++ LAQ LQ E +E ASL+ RL NE DLM +E+ + L Sbjct: 1376 EENNRQQQLLAQNLQLPPEARIE------ASLQHEITRLTNENLDLMEQLEKQDKTVRKL 1429 Query: 1449 DKKQRNFDKILAE 1461 K+ + F K + E Sbjct: 1430 KKQLKVFAKKIGE 1442 Score = 100 bits (248), Expect = 2e-20 Identities = 180/793 (22%), Positives = 324/793 (40%), Gaps = 106/793 (13%) Query: 795 QARCRGFLARVEYQRMVERREAIFCIQYNIRSFMNVKHWP-WMKLFFKIKPLLKSAETEK 853 Q+ RGFLAR Y++++ +A+ IQ +R ++ H+ M ++ + ++ Sbjct: 845 QSYLRGFLARNRYRKILREHKAVI-IQKRVRGWLARTHYKRSMHAIIYLQCCFRRMMAKR 903 Query: 854 EMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCDQ 913 E+ +K E A+S + K+L M E +QLQ + + + + + +C Sbjct: 904 ELKKLKIE--------ARSVERYKKLHIGM-----ENKIMQLQRKVDEQ---NKDYKC-- 945 Query: 914 LIKTKIQLEA-------KIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELT 966 L++ LE K++ ER + EE T + L++E ++L+KD++ Sbjct: 946 LVEKLTNLEGIYNSETEKLRSDLERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSE 1005 Query: 967 LAKVEKE----KHATENKVKNLTEEMAGLDETIAKL-------------TKEKKALQEAH 1009 +E+ K TE V NL EE L + L T EKK ++E Sbjct: 1006 KKCIEEHADRYKQETEQLVSNLKEENTLLKQEKEALNHRIVQQAKEMTETMEKKLVEETK 1065 Query: 1010 QQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQ 1069 Q L DL E + L +LE++ DD L++E L + + + K + Sbjct: 1066 QLEL-DLNDERLRYQNLLNEFSRLEERYDD----LKEEMTLMVHVPKPGHKRTDSTHSSN 1120 Query: 1070 ESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIE 1129 ES +E ++++ + E + K+ + +L ++LQK++ EL+ + +++E++ Sbjct: 1121 ESEYIFSSEIAEMEDIPSRTE---EPSEKKVPLDMSLFLKLQKRVTELEQEKQVMQDELD 1177 Query: 1130 AER----ASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLE 1185 + S+AK E++ ELE S + +E NKK + E ++R+ L Sbjct: 1178 RKEEQVLRSKAKEEERPQIRGAELEYESLKRQELESE-------NKKLKNELNELRKALS 1230 Query: 1186 EATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVS 1245 E +A + A + L EQ L V ++L+ K E+ + L S E + Sbjct: 1231 ------EKSAPEVTAPGAPAYRVLMEQ---LTSVSEELDVRKEEVLILRSQLVSQKEAIQ 1281 Query: 1246 -KAKGNLEKMCRTLEDQLSELKSKEEEQQRLI-----NDLTAQRGRLQTESGE----FSR 1295 K N L + + ++K K E Q I N +A E GE + Sbjct: 1282 PKDDKNTMTDSTILLEDVQKMKDKGEIAQAYIGLKETNRSSALDYHELNEDGELWLVYEG 1341 Query: 1296 QLDEKEALVSQLSRGKQAFTQQIEELKRQL----EEEIKAKNALAHALQ---SSRHDCDL 1348 L SQL K++ + E L+ ++ EE + + LA LQ +R + L Sbjct: 1342 LKQANRLLESQLQSQKRSHENEAEALRGEIQSLKEENNRQQQLLAQNLQLPPEARIEASL 1401 Query: 1349 LREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEE 1408 E E+ +L L K + V + + + + A ++ ELE + + Q +E Sbjct: 1402 QHEITRLTNEN-LDLMEQLEKQDKTVRKLKKQLKVFA-KKIGELEVGQMENISPGQIIDE 1459 Query: 1409 HVEAVNAK------CASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEW 1462 + VN LE K+ Q V++L+L+++ A N L + Sbjct: 1460 PIRPVNIPRKEKDFQGMLEYKKEDEQKLVKNLILELKPRGVAV--------NLIPGLPAY 1511 Query: 1463 KQKCEETHAELEASQKEARSLGTE-LFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQ 1521 HA+ ++ RSL T + IK ++ D ET+ N + + L + Sbjct: 1512 ILFMCVRHADYLNDDQKVRSLLTSTINSIKKVLKKRGDDFETVSFWLSNTCRFLHCLKQY 1571 Query: 1522 IAEGGKRIHELEK 1534 E G H + Sbjct: 1572 SGEEGFMKHNTSR 1584 Score = 79.3 bits (194), Expect = 3e-14 Identities = 128/572 (22%), Positives = 246/572 (43%), Gaps = 106/572 (18%) Query: 1086 LKKKEFEISNLQSK-IEDEQALGIQLQKKIKELQARIEE--------LEEEIEAERASRA 1136 + K+E + ++++ +E + L I ++ KI +LQ +++E +E+ E + Sbjct: 900 MAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNS 959 Query: 1137 KAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAA 1196 + EK RSDL R ++SE EEA AT + + + E K+R+DLE+ + + Sbjct: 960 ETEKLRSDLERL--QLSE--EEAKVATGRVLSLQE----EIAKLRKDLEQTRSEKKCI-- 1009 Query: 1197 TLRKKHADSVAELGEQ-IDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMC 1255 ++HAD + EQ + NL+ L++EK A N V +AK +M Sbjct: 1010 ---EEHADRYKQETEQLVSNLKEENTLLKQEKE---------ALNHRIVQQAK----EMT 1053 Query: 1256 RTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFT 1315 T+E +L E E ++L DL +R R Q EFSR + + L +++ Sbjct: 1054 ETMEKKLVE------ETKQLELDLNDERLRYQNLLNEFSRLEERYDDLKEEMT-----LM 1102 Query: 1316 QQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRAL----SKAN 1371 + + + + + N + S + + + + EE E K L +L K Sbjct: 1103 VHVPKPGHKRTDSTHSSNESEYIFSSEIAEMEDIPSRTEEPSEKKVPLDMSLFLKLQKRV 1162 Query: 1372 TEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEV 1431 TE+ Q + + + ++ E++ +K K +R Q +E + K LE ++L+NE+ Sbjct: 1163 TELEQEKQVMQDELDRKEEQVLRSKAKEEERPQIRGAELEYESLKRQELESENKKLKNEL 1222 Query: 1432 EDLMLDVERTNA---------ACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEA-- 1480 +L + +A A L ++ + + L K++ ++L SQKEA Sbjct: 1223 NELRKALSEKSAPEVTAPGAPAYRVLMEQLTSVSEELDVRKEEVLILRSQL-VSQKEAIQ 1281 Query: 1481 ----RSLGTELFKIKNAYEESLDQLET------LKRENKNLQQEISDLTEQ-----IAEG 1525 ++ T+ + ++ D+ E LK N++ + +L E + EG Sbjct: 1282 PKDDKNTMTDSTILLEDVQKMKDKGEIAQAYIGLKETNRSSALDYHELNEDGELWLVYEG 1341 Query: 1526 GKRIH-----ELEKIKKQVEQE----KCELQAALEE-------------------AEASL 1557 K+ + +L+ K+ E E + E+Q+ EE EASL Sbjct: 1342 LKQANRLLESQLQSQKRSHENEAEALRGEIQSLKEENNRQQQLLAQNLQLPPEARIEASL 1401 Query: 1558 EHEEGKILRIQLELNQVKSEVDRKIAEKDEEI 1589 +HE ++ L+L + + D+ + + +++ Sbjct: 1402 QHEITRLTNENLDLMEQLEKQDKTVRKLKKQL 1433 Score = 56.6 bits (135), Expect = 2e-07 Identities = 103/477 (21%), Positives = 204/477 (42%), Gaps = 92/477 (19%) Query: 1472 ELEASQKEARSLGTELFKIKNAYEESLDQLET-LKRENKNLQQEISDLTEQIAEGGKRIH 1530 EL+ + EARS+ K+ E + QL+ + +NK+ + + LT G Sbjct: 904 ELKKLKIEARSV-ERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNL---EGIYNS 959 Query: 1531 ELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEK---DE 1587 E EK++ +E+ LQ + EEA+ + G++L +Q E+ +++ ++++ +EK +E Sbjct: 960 ETEKLRSDLER----LQLSEEEAKVAT----GRVLSLQEEIAKLRKDLEQTRSEKKCIEE 1011 Query: 1588 EIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALR 1647 D+ K+ ++V ++ + + LK++ E LNH A+ + Sbjct: 1012 HADRYKQETEQLVSNL----------KEENTLLKQEKEA--------LNHRIVQQAKEMT 1053 Query: 1648 NYRNTQGILKDTQIHLD---DALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERS 1704 + + + Q+ LD + LR Q L E + ER +L EE+ + + Sbjct: 1054 ETMEKKLVEETKQLELDLNDERLRYQNLLNEFSRLEERYDDLK----EEMTLMVHVPKPG 1109 Query: 1705 RKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKA 1764 K R H+ N S E S EMEDI +R E KK Sbjct: 1110 HK-----------RTDSTHSSNES--------EYIFSSEIAEMEDI--PSRTEEPSEKKV 1148 Query: 1765 ITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEAR 1824 D ++ + L++ +EQ + +Q LD E+ L+ K+ ++ + R Sbjct: 1149 PLDMSLFLK-----------LQKRVTELEQEKQVMQDELDRKEEQVLRSKAKEEERPQIR 1197 Query: 1825 VRELE------GEVESEQKRNAEAVKGLRK--HERRVKELTYQTEEDRKNIL-RLQDLVD 1875 ELE E+ESE K+ + LRK E+ E+T + ++ +L + + Sbjct: 1198 GAELEYESLKRQELESENKKLKNELNELRKALSEKSAPEVTAPGAPAYRVLMEQLTSVSE 1257 Query: 1876 KLQAKVKSY---------KRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAESQV 1923 +L + + +++A + ++ NT + L ++++ +++ +IA++ + Sbjct: 1258 ELDVRKEEVLILRSQLVSQKEAIQPKDDKNT-MTDSTILLEDVQKMKDKGEIAQAYI 1313 Score = 54.3 bits (129), Expect = 1e-06 Identities = 76/339 (22%), Positives = 136/339 (40%), Gaps = 38/339 (11%) Query: 1607 LDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDA 1666 L E RS +L ME + +++ +++ N+ + N +GI L Sbjct: 908 LKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNSETEKLRSD 967 Query: 1667 LRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQEL----LDASERVQLL 1722 L + +E+ + R LQ EI +LR LEQT +K E+ + + V L Sbjct: 968 LERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKCIEEHADRYKQETEQLVSNL 1027 Query: 1723 HTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTS 1782 +NT L K+ L I Q EM + ++ KK + + + +L E+ Sbjct: 1028 KEENTLLKQEKEALNHRIVQQAKEMTETME---------KKLVEETKQLELDLNDERLRY 1078 Query: 1783 AHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQK---------LEARVRELEG--- 1830 +L +E+ DL+ + + G K+ + + E+E Sbjct: 1079 QNLLNEFSRLEERYDDLKEEMTLMVHVPKPGHKRTDSTHSSNESEYIFSSEIAEMEDIPS 1138 Query: 1831 --EVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQA 1888 E SE+K + L K ++RV EL E K ++ QD +D+ + +V K + Sbjct: 1139 RTEEPSEKKVPLDMSLFL-KLQKRVTEL-----EQEKQVM--QDELDRKEEQVLRSKAKE 1190 Query: 1889 EEAEEQSNTNLAKFRKLQHELEEAEERADIAESQVNKLR 1927 EE + L + ELE ++ ++++N+LR Sbjct: 1191 EERPQIRGAELEYESLKRQELESENKKL---KNELNELR 1226 >gi|122937345 myosin VB [Homo sapiens] Length = 1848 Score = 564 bits (1454), Expect = e-160 Identities = 462/1608 (28%), Positives = 769/1608 (47%), Gaps = 191/1608 (11%) Query: 36 TSVFVAEPKESFVKGTIQS--REGGK-VTVKTEGGATLT----VKDDQV-FPMNPPKYDK 87 T V++ +P E + + +EG K + ++ E L V+ +Q+ F NP Sbjct: 11 TRVWIPDPDEVWRSAELTKDYKEGDKSLQLRLEDETILEYPIDVQRNQLPFLRNPDILVG 70 Query: 88 IEDMAMMTHLHEPAVLYNLKERYA-AWMIYTYSGLFCVTVNPYKWLPVYKPEVVTAYRGK 146 D+ +++LHEPAVL+NLK R+ + IYTY G+ V +NPY+ LP+Y +V+ Y G+ Sbjct: 71 ENDLTALSYLHEPAVLHNLKVRFLESNHIYTYCGIVLVAINPYEQLPIYGQDVIYTYSGQ 130 Query: 147 KRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKK 206 + PHIF++++ AY+ M D +NQSI+++GESGAGKTV+ K ++YFAT+ + + Sbjct: 131 NMGDMDPHIFAVAEEAYKQMARDEKNQSIIVSGESGAGKTVSAKYAMRYFATVGGSASET 190 Query: 207 KEEITSGKIQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADI 266 +E+++++++P++EA GNAKT RNDNSSRFGK+I+I F + A++ Sbjct: 191 N-----------IEEKVLASSPIMEAIGNAKTTRNDNSSRFGKYIQIGFDKRYHIIGANM 239 Query: 267 ETYLLEKSRVVFQLKAERSYHIFYQITSNKK-PELIEMLLITTNPYDYPFVSQG-EISVA 324 TYLLEKSRVVFQ ER+YHIFYQ+ + PE E+ L T+ D+ + SQG + S+ Sbjct: 240 RTYLLEKSRVVFQADDERNYHIFYQLCAAAGLPEFKELAL--TSAEDFFYTSQGGDTSIE 297 Query: 325 SIDDQEELMATDSAIDILGFTNEEKVSIYKLTGAVMHYGNLKFKQKQREEQAEPDGTE-- 382 +DD E+ T A +LG ++SI+K+ +++H G++ QAE DG Sbjct: 298 GVDDAEDFEKTRQAFTLLGVKESHQMSIFKIIASILHLGSVAI-------QAERDGDSCS 350 Query: 383 VADKAAYLQS------LNSADLLKALCYPRVKVGNEYVTKGQTVEQVSNAVGALAKAVYE 436 ++ + YL + + + + LC+ ++ +E K +++QV NA ALAK +Y Sbjct: 351 ISPQDVYLSNFCRLLGVEHSQMEHWLCHRKLVTTSETYVKTMSLQQVINARNALAKHIYA 410 Query: 437 KMFLWMVARINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHM 496 ++F W+V IN+ L T + FIGVLDI GFE F+ NS EQ CIN+ NEKLQQ FN H+ Sbjct: 411 QLFGWIVEHINKALHTSLKQHSFIGVLDIYGFETFEVNSFEQFCINYANEKLQQQFNSHV 470 Query: 497 FVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLY 556 F LEQEEY KE I WT IDF D CI+LIE +GI +L+EEC PK TD ++ KLY Sbjct: 471 FKLEQEEYMKEQIPWTLIDF-YDNQPCIDLIEAKLGILDLLDEECKVPKGTDQNWAQKLY 529 Query: 557 DQHLGKSANFQKPKVVKGKAEAHFALIHYAGVVDYNITGWLEKNKDPLNETVVGLYQKSA 616 D+H S +FQKP++ + F ++H+A V+Y G+LEKN+D + E + + + S Sbjct: 530 DRH-SSSQHFQKPRM----SNTAFIIVHFADKVEYLSDGFLEKNRDTVYEEQINILKASK 584 Query: 617 MKTLAQLFSGAQ-----TAEGEGAGG-----GAKKGGKKKGSSFQ-TVSALFRENLNKLM 665 +A LF + T G+G+ A+ K + TV FR +L+ LM Sbjct: 585 FPLVADLFHDDKDPVPATTPGKGSSSKISVRSARPPMKVSNKEHKKTVGHQFRTSLHLLM 644 Query: 666 TNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFK 725 L +T PH+VRCI PN+ K P + + + QLR GVLE IRI G+PSR Y DF Sbjct: 645 ETLNATTPHYVRCIKPNDEKLPFHFDPKRAVQQLRACGVLETIRISAAGYPSRWAYHDFF 704 Query: 726 QRYKVLNASAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDD 785 RY+VL E D K +L ++ D +++FG TK+FF+AG + LE++R D Sbjct: 705 NRYRVLVKKR--ELANTDKKAICRSVLENLIKDPDKFQFGRTKIFFRAGQVAYLEKLRAD 762 Query: 786 KLAQ---LITRT--------------------QARCRGFLARVEYQRMVERREAI----- 817 K +I +T Q CRG LAR + + R A+ Sbjct: 763 KFRTATIMIQKTVRGWLQKVKYHRLKGATLTLQRYCRGHLARRLAEHLRRIRAAVVLQKH 822 Query: 818 FCIQYNIRSFMNVKHWPWMKLFFKIKPLLKSAETEKEMATMKEEFQKIKDELAKSEAKRK 877 + +Q +++ V+ + F ++ + M+ + I+ + A+R Sbjct: 823 YRMQRARQAYQRVRRAAVVIQAFTRAMFVRRTYRQ---VLMEHKATTIQKHVRGWMARRH 879 Query: 878 ELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEE 937 + ++ + L+ + E + L + L + + +E K+ ++ + +++ Sbjct: 880 FQRLRDAAIVIQCAFRMLKARRELKALRIEARSAEHLKRLNVGMENKVVQLQRKIDEQ-- 937 Query: 938 INAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAK 997 N E +L S +++ L+ L V ++ E+ L EE+ L + + Sbjct: 938 -NKEFKTLSEQLSVTTSTYTMEVERLKKEL--VHYQQSPGEDTSLRLQEEVESLRTELQR 994 Query: 998 LTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERA 1057 E+K L++AH + D+L+ ++V D LEQE L L+ Sbjct: 995 AHSERKILEDAHSREKDELR-----------------KRVAD----LEQENAL---LKDE 1030 Query: 1058 KRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKEL 1117 K +L + + E + + E L KKE +E+E++ L K+ +L Sbjct: 1031 KEQLNNQILCQSKD----EFAQNSVKENLMKKE---------LEEERSRYQNLVKEYSQL 1077 Query: 1118 QARIEELEEE--IEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREA 1175 + R + L +E I + + +S L + S E G A Sbjct: 1078 EQRYDNLRDEMTIIKQTPGHRRNPSNQSSLESDSNYPSISTSEIGDTEDA---------- 1127 Query: 1176 EFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEID 1235 + +EE L+ A T+ K V EL ++ LQ +K E++ S+ K++ + Sbjct: 1128 -----LQQVEEIGLEKAAMDMTVFLKLQKRVRELEQERKKLQVQLEKREQQDSK-KVQAE 1181 Query: 1236 DLASNVETVSKAKGNLEKMCR-TLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFS 1294 ++++ A + R LE + +LK+ E ++ + D Q +S Sbjct: 1182 PPQTDIDLDPNADLAYNSLKRQELESENKKLKNDLNELRKAVADQATQNNSSHGSPDSYS 1241 Query: 1295 RQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYE 1354 L++ + +L K +++ L+ Q+ + + A +A + + Sbjct: 1242 LLLNQLKLAHEELEVRK----EEVLILRTQIVSADQRRLAGRNAEPNINARSSWPNSEKH 1297 Query: 1355 EEQESKAELQRALSKANTEVAQWRTKYETDAIQRT-EELEEAKKKLAQRLQAAE-EHVEA 1412 +QE E + + N++ W E + + L++ + L +LQA EH E Sbjct: 1298 VDQEDAIEAYHGVCQTNSKTEDWGYLNEDGELGLAYQGLKQVARLLEAQLQAQSLEHEEE 1357 Query: 1413 VNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAE 1472 V A LE K+ +DK+Q+ F + L E E Sbjct: 1358 VEHLKAQLEALKEE---------------------MDKQQQTFCQTLL----LSPEAQVE 1392 Query: 1473 LEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDL--TEQIAEGGKRIH 1530 Q+ +R L E +K E+ LK++ K ++ DL + +A+ ++ H Sbjct: 1393 FGVQQEISR-LTNENLDLKELVEKLEKNERKLKKQLKIYMKKAQDLEAAQALAQSERKRH 1451 Query: 1531 ELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEV 1578 EL + + V++++ + Q LE H+E + L I+ + +K ++ Sbjct: 1452 ELNR-QVTVQRKEKDFQGMLE------YHKEDEALLIRNLVTDLKPQM 1492 Score = 63.9 bits (154), Expect = 1e-09 Identities = 129/605 (21%), Positives = 242/605 (40%), Gaps = 107/605 (17%) Query: 1329 IKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQR 1388 +KA+ L AL+ + L+ + +LQR + + N E + Sbjct: 897 LKARRELK-ALRIEARSAEHLKRLNVGMENKVVQLQRKIDEQNKEFKTLSEQLSVTTSTY 955 Query: 1389 TEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAAL 1448 T E+E KK+L Q+ E T RLQ EVE L +++R ++ L Sbjct: 956 TMEVERLKKELVHYQQSPGED-------------TSLRLQEEVESLRTELQRAHSERKIL 1002 Query: 1449 --------------------------DKKQRNFDKILAEWKQKCEETHA-------ELEA 1475 D+K++ ++IL + K + + ELE Sbjct: 1003 EDAHSREKDELRKRVADLEQENALLKDEKEQLNNQILCQSKDEFAQNSVKENLMKKELEE 1062 Query: 1476 SQKEARSLGTELFKIKNAYEESLDQLETLK-----RENKNLQQEISDLTEQIAEGGKRIH 1530 + ++L E +++ Y+ D++ +K R N + Q + + + I Sbjct: 1063 ERSRYQNLVKEYSQLEQRYDNLRDEMTIIKQTPGHRRNPSNQSSLESDSNYPSISTSEIG 1122 Query: 1531 ELEKIKKQVEQEKCELQA-------ALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIA 1583 + E +QVE+ E A L++ LE E K +Q++L + + + +K+ Sbjct: 1123 DTEDALQQVEEIGLEKAAMDMTVFLKLQKRVRELEQERKK---LQVQLEKREQQDSKKVQ 1179 Query: 1584 EKDEEID-QLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMA 1642 + + D L N S++ E+ S N KK++ DLNE+ +A Sbjct: 1180 AEPPQTDIDLDPNADLAYNSLKR---QELESEN------KKLKNDLNELR------KAVA 1224 Query: 1643 AEALRNYRNTQGILKDTQIHLDDALRSQEDL---KEQLAMVERRANLLQAEIEEL---RA 1696 +A +N ++ G + L+ + E+L KE++ ++ R ++ A+ L A Sbjct: 1225 DQATQN-NSSHGSPDSYSLLLNQLKLAHEELEVRKEEVLIL--RTQIVSADQRRLAGRNA 1281 Query: 1697 TLEQTERSRKIAEQELLDASERVQLLH--------TQNTSLINTKKKL---ETDISQMQG 1745 RS ++ +D + ++ H T++ +N +L + Q+ Sbjct: 1282 EPNINARSSWPNSEKHVDQEDAIEAYHGVCQTNSKTEDWGYLNEDGELGLAYQGLKQVAR 1341 Query: 1746 EMEDILQ-EARNAEEKAKKAITDAAMMAEELKKEQDTSAH--LERMKKNMEQTVKDLQLR 1802 +E LQ ++ EE+ + + EE+ K+Q T L + +E V+ R Sbjct: 1342 LLEAQLQAQSLEHEEEVEHLKAQLEALKEEMDKQQQTFCQTLLLSPEAQVEFGVQQEISR 1401 Query: 1803 LDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKR--NAEAVKGLRKHERRVKELTYQT 1860 L E L L K+ ++KLE R+L+ +++ K+ + EA + L + ER+ EL Q Sbjct: 1402 LTN-ENLDL---KELVEKLEKNERKLKKQLKIYMKKAQDLEAAQALAQSERKRHELNRQV 1457 Query: 1861 EEDRK 1865 RK Sbjct: 1458 TVQRK 1462 Score = 47.8 bits (112), Expect = 1e-04 Identities = 78/371 (21%), Positives = 148/371 (39%), Gaps = 57/371 (15%) Query: 1607 LDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDA 1666 L E RS RL ME + +++ +++ N+ T T + + Sbjct: 906 LRIEARSAEHLKRLNVGMENKVVQLQRKIDEQNKEFKTLSEQLSVT------TSTYTMEV 959 Query: 1667 LRSQEDLKE-QLAMVERRANLLQAEIEELRATLEQTERSRKIAE----QELLDASERVQL 1721 R +++L Q + E + LQ E+E LR L++ RKI E +E + +RV Sbjct: 960 ERLKKELVHYQQSPGEDTSLRLQEEVESLRTELQRAHSERKILEDAHSREKDELRKRVAD 1019 Query: 1722 LHTQNTSLINTKKKLETDI-----------SQMQGEMEDILQEARNAEEKAKKAITDAAM 1770 L +N L + K++L I S + M+ L+E R+ + K + Sbjct: 1020 LEQENALLKDEKEQLNNQILCQSKDEFAQNSVKENLMKKELEEERSRYQNLVKEYSQLEQ 1079 Query: 1771 MAEELKKEQDTSAHLERMKKN----------------MEQTVKDLQLRLDEAEQLALKGG 1814 + L+ E ++N + D + L + E++ L+ Sbjct: 1080 RYDNLRDEMTIIKQTPGHRRNPSNQSSLESDSNYPSISTSEIGDTEDALQQVEEIGLEKA 1139 Query: 1815 KKQIQ---KLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEED-------R 1864 + KL+ RVRELE E +K + K ++ ++V+ QT+ D Sbjct: 1140 AMDMTVFLKLQKRVRELEQE---RKKLQVQLEKREQQDSKKVQAEPPQTDIDLDPNADLA 1196 Query: 1865 KNILRLQDLVD---KLQAKVKSYKRQAEEAEEQSNTNLA---KFRKLQHELEEAEERADI 1918 N L+ Q+L KL+ + ++ + Q+N++ + L ++L+ A E ++ Sbjct: 1197 YNSLKRQELESENKKLKNDLNELRKAVADQATQNNSSHGSPDSYSLLLNQLKLAHEELEV 1256 Query: 1919 AESQVNKLRVK 1929 + +V LR + Sbjct: 1257 RKEEVLILRTQ 1267 >gi|28416946 myosin 18A isoform a [Homo sapiens] Length = 2054 Score = 509 bits (1310), Expect = e-143 Identities = 434/1710 (25%), Positives = 822/1710 (48%), Gaps = 227/1710 (13%) Query: 58 GKVTVKTE-GGATLTVKDDQVFPMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIY 116 GKV VK + GA L V +D V N P D++ED+A + +L+E +VL+ L++RY A +++ Sbjct: 376 GKVRVKLDHDGAILDVDEDDVEKANAPSCDRLEDLASLVYLNESSVLHTLRQRYGASLLH 435 Query: 117 TYSGLFCVTVNPYKWLPVYKPEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSIL 176 TY+G + + P VY +V+ ++G +R++ PHI++++ AY+ ML R++QSI+ Sbjct: 436 TYAGPSLLVLGPRGAPAVYSEKVMHMFKGCRREDMAPHIYAVAQTAYRAMLMSRQDQSII 495 Query: 177 ITGESGAGKTVNTKRVIQYFATIAVTGEKKKEEITSGKIQGTLEDQIISANPLLEAFGNA 236 + G SG+GKT + + ++QY ATIA I+ K+ + Q + LLEAFGN+ Sbjct: 496 LLGSSGSGKTTSCQHLVQYLATIA--------GISGNKVFSVEKWQALYT--LLEAFGNS 545 Query: 237 KTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVVFQLKAERSYHIFYQITS-- 294 T+ N N++RF + + + F G++ASA I+T LLEK RV + +E ++++FY + + Sbjct: 546 PTIINGNATRFSQILSLDFDQAGQVASASIQTMLLEKLRVARRPASEATFNVFYYLLACG 605 Query: 295 --NKKPELIEMLLITTNPYDYPFVSQGEISVASIDDQEELMATDSAIDILGFTNEEKVSI 352 + EL L N + +++ E + +L A A+ +LG + +E+ + Sbjct: 606 DGTLRTELHLNHLAENNVFGIVPLAKPEEKQKAAQQFSKLQA---AMKVLGISPDEQKAC 662 Query: 353 YKLTGAVMHYGNLKFKQKQREEQAEPDGT-EVADKAAYLQSLNSADLLKALCYPRVKVG- 410 + + A+ H G ++ E + E A KAAYL + +L A+ + K G Sbjct: 663 WFILAAIYHLGAAGATKEAAEAGRKQFARHEWAQKAAYLLGCSLEELSSAIFKHQHKGGT 722 Query: 411 ---NEYVTKGQTVEQVSNAVG----------ALAKAVYEKMFLWMVARINQQLDTKQPRQ 457 + +G + + G +A +Y ++F +V+ +N+ L + Q Sbjct: 723 LQRSTSFRQGPEESGLGDGTGPKLSALECLEGMAAGLYSELFTLLVSLVNRALKSSQHSL 782 Query: 458 YFIGVLDIAGFEIFDFN------SLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEW 511 + ++D GF+ + S E+LC N+T ++LQ+ F+ FV E E YK+E IE Sbjct: 783 CSMMIVDTPGFQNPEQGGSARGASFEELCHNYTQDRLQRLFHERTFVQELERYKEENIEL 842 Query: 512 TFIDF---------GMDLAACIELI------EKPMGIFSILEEECMFPKATDTSFKNKLY 556 F D +D A+ L+ ++ G+ +LEEE + P A++ + +L+ Sbjct: 843 AFDDLEPPTDDSVAAVDQASHQSLVRSLARTDEARGLLWLLEEEALVPGASEDTLLERLF 902 Query: 557 DQHLGKSAN--FQKPKVVKGKAEAHFALIHYAGV--VDYNITGWLEKNK-DPLNETVVGL 611 + + + Q P + K HF L H G V+YN+TGWL K +P + L Sbjct: 903 SYYGPQEGDKKGQSPLLHSSKPH-HFLLGHSHGTNWVEYNVTGWLNYTKQNPATQNAPRL 961 Query: 612 YQKSAMKTLAQLFSG----AQTAEGEGAG--GGAKKGGKKKGSSFQT----VSALFRENL 661 Q S K ++ LF G A G AG GG++ ++ S +T ++A+ +++L Sbjct: 962 LQDSQKKIISNLFLGRAGSATVLSGSIAGLEGGSQLALRRATSMRKTFTTGMAAVKKKSL 1021 Query: 662 --------NKLMTNLRSTHPHFVRCIIP--------------------NETKTPGA---- 689 + L+ ++ + HFV C +P +E P Sbjct: 1022 CIQMKLQVDALIDTIKKSKLHFVHCFLPVAEGWAGEPRSASSRRVSSSSELDLPSGDHCE 1081 Query: 690 -----MEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQ---- 740 ++ L+ QLR + +L+ +R+ R+G+P +++++F++R+ VL + Sbjct: 1082 AGLLQLDVPLLRTQLRGSRLLDAMRMYRQGYPDHMVFSEFRRRFDVLAPHLTKKHGRNYI 1141 Query: 741 FIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDDKLAQLITRTQARCRG 800 +D ++A E+LL +D++ + G ++VFF+AG L LEE RD++ ++ +T QA CRG Sbjct: 1142 VVDERRAVEELLECLDLEKSSCCMGLSRVFFRAGTLARLEEQRDEQTSRNLTLFQAACRG 1201 Query: 801 FLARVEYQRMVERREAIFCIQYNIRSFMNVKHWPWMKLFFKIKPLLKSAETEKEMATMKE 860 +LAR +++ + AI C+Q NI+ VK WPW KLF ++PL++ +E+++ E Sbjct: 1202 YLARQHFKKRKIQDLAIRCVQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKDE 1261 Query: 861 EFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCDQLIKTKIQ 920 E Q+++ +L K+E +R EL L ++L ++ E A + D +++ Sbjct: 1262 EIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDAETAERLR 1321 Query: 921 LEAKIKEVTER--AEDEEEINAELTAKKRKLEDECSELKKDIDDLEL---TLAKVEKEKH 975 E ++KE+ + A ++ E+ + +L +E+ ++DD + K E+ Sbjct: 1322 AEKEMKELQTQYDALKKQMEVMEMEVMEARL-IRAAEINGEVDDDDAGGEWRLKYERAVR 1380 Query: 976 ATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDK----VNTLTKAKI 1031 + K L +E ++ + + K+ L ++ L DLQA+ ++ + L K Sbjct: 1381 EVDFTKKRLQQE---FEDKLEVEQQNKRQL----ERRLGDLQADSEESQRALQQLKKKCQ 1433 Query: 1032 KLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEF 1091 +L ++ D + LE ++ +LE+ +R+ + +L A E + + EK Q ++ ++K+ Sbjct: 1434 RLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHE---EAQREKLQREKLQREKDM 1490 Query: 1092 ---EISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRE 1148 E +L+ ++E++ +K+ L+A ++++ + + AS AK +KQ DL + Sbjct: 1491 LLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAK 1550 Query: 1149 LEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAE 1208 +++ E L+E G I+M LE+A L+ E +R+ H+ + Sbjct: 1551 VKDQEEELDEQAGT----IQM--------------LEQAKLRLEMEMERMRQTHSKEMES 1592 Query: 1209 LGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSK 1268 E++ + +Q +K+ +M++++++ + + V + K LE TL DQ++ + Sbjct: 1593 RDEEV---EEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVN--RRD 1647 Query: 1269 EEEQQRLINDLTAQRGRL----------------QTESGEFSRQLDEKEALVSQLSRGKQ 1312 E ++RL DL + L + E + QL+E E + + ++ Sbjct: 1648 FESEKRLRKDLKRTKALLADAQLMLDHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARK 1707 Query: 1313 AFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQR----ALS 1368 A +IE+L Q+++ KAK AL L + + + ++ + EE+QE EL + A++ Sbjct: 1708 AMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVA 1767 Query: 1369 KANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVE-----AVNAKCASLEKT 1423 +A+ ++AQ D + EE + K++L ++LQA + VE V+ S ++ Sbjct: 1768 QASRDLAQ-----INDLQAQLEEANKEKQELQEKLQALQSQVEFLEQSMVDKSLVSRQEA 1822 Query: 1424 KQR-LQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARS 1482 K R L+ +E V+R + + L + N +K+ E Q+ + E E +++ Sbjct: 1823 KIRELETRLEFERTQVKRLESLASRL---KENMEKLTEERDQRIAAENREKEQNKR---- 1875 Query: 1483 LGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQE 1542 L+R+ ++ ++E+ +L + AE ++ HELE + +E Sbjct: 1876 ---------------------LQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAA 1914 Query: 1543 KCELQAALEEA-----------EASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQ 1591 LQA L+ A E +E +E + L L+ K + + E D ++D Sbjct: 1915 NQSLQADLKLAFKRIGDLQAAIEDEMESDENEDLINSLQDMVTKYQKRKNKLEGDSDVDS 1974 Query: 1592 LKRNHIRIVESMQSTLDAEIRSRNDAIRLK 1621 + + V+S S ++ +D LK Sbjct: 1975 ELEDRVDGVKSWLSKNKGPSKAASDDGSLK 2004 Score = 186 bits (471), Expect = 3e-46 Identities = 158/694 (22%), Positives = 330/694 (47%), Gaps = 61/694 (8%) Query: 1252 EKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQL-DEKEA--LVSQLS 1308 E+ R ++++ +L+SK E+ ++ N+L RL++ E + +L DE+ SQL Sbjct: 1253 EEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLL 1312 Query: 1309 RGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQY----EEEQESKAELQ 1364 + A + E+ ++L+ + A ++ + L+R ++ ++ E + Sbjct: 1313 DAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWR 1372 Query: 1365 RALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTK 1424 +A EV + + + + + E ++ K++L +RL + E L+K Sbjct: 1373 LKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKC 1432 Query: 1425 QRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLG 1484 QRL E++D L +E L+KKQR FD L++ ++ + + E Q+E L Sbjct: 1433 QRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLL 1492 Query: 1485 TELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKC 1544 E F +K EE + ++ +L+ E+ D++ Q K L K+KKQ+ Sbjct: 1493 AEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQ---ESKDEASLAKVKKQLR---- 1545 Query: 1545 ELQAALEEAEASLEHEEGKI-------LRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHI 1597 +L+A +++ E L+ + G I LR+++E+ +++ +++ +DEE+++ +++ Sbjct: 1546 DLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQ 1605 Query: 1598 RIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALR-NYRNTQGIL 1656 + ++ M+ L+ E + +R K+++EG L + Q+N + + + LR + + T+ +L Sbjct: 1606 KKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALL 1665 Query: 1657 KDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDAS 1716 D Q+ LD L++ K ++A L+ ++EE T ++RK E E+ D Sbjct: 1666 ADAQLMLDH-LKNSAPSKREIAQ-------LKNQLEESEFTCAAAVKARKAMEVEIED-- 1715 Query: 1717 ERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELK 1776 LH Q + K LE +S++Q E +I +E M E +K Sbjct: 1716 -----LHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQED----------MNELMK 1760 Query: 1777 KEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQ 1836 K + A + + +++ Q + DLQ +L+EA K+ Q+L+ +++ L+ +VE + Sbjct: 1761 KHK---AAVAQASRDLAQ-INDLQAQLEEA--------NKEKQELQEKLQALQSQVEFLE 1808 Query: 1837 KRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSN 1896 + + + + E +++EL + E +R + RL+ L +L+ ++ + ++ N Sbjct: 1809 QSMVDK-SLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEERDQRIAAEN 1867 Query: 1897 TNLAKFRKLQHELEEA-EERADIAESQVNKLRVK 1929 + ++LQ +L + EE ++A + R K Sbjct: 1868 REKEQNKRLQRQLRDTKEEMGELARKEAEASRKK 1901 Score = 154 bits (390), Expect = 6e-37 Identities = 206/921 (22%), Positives = 402/921 (43%), Gaps = 138/921 (14%) Query: 945 KKRKLED--ECSELKKDIDDLEL--------TLAKVEKEKHATENKVKNLTEEMAGLDET 994 ++R +E+ EC +L+K + L TLA++E+++ E +NLT A Sbjct: 1145 ERRAVEELLECLDLEKSSCCMGLSRVFFRAGTLARLEEQRD--EQTSRNLTLFQAACRGY 1202 Query: 995 IAKLTKEKKALQEAH----QQTLDDLQAEED----KVNTLTKAKIKLEQQVDDLEGSLEQ 1046 +A+ +K+ +Q+ Q+ + + +D K+ T + I+++ + + E+ Sbjct: 1203 LARQHFKKRKIQDLAIRCVQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKDEE 1262 Query: 1047 EKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQAL 1106 ++LR LE+A+++ +L+L + + E+ +L +L + + ++ E A Sbjct: 1263 IQQLRSKLEKAEKE-RNELRLNSDRL---ESRISELTSELTDERNTGESASQLLDAETAE 1318 Query: 1107 GIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRS-DLSRELEEISERLEEAGGATSA 1165 ++ +K++KELQ + + L++++E +A R+ +++ E+++ ++AGG Sbjct: 1319 RLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDD-----DDAGGEWRL 1373 Query: 1166 QIEMNKKREAEFQKMR--RDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKL 1223 + E RE +F K R ++ E+ + L ++ D A+ E QR Q+L Sbjct: 1374 KYE-RAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEES----QRALQQL 1428 Query: 1224 EKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQR 1283 +K+ + E+ D ++E LEK R + +LS+ + + ++ L ++ Sbjct: 1429 KKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREK 1488 Query: 1284 GRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEE----EIKAKNALAHAL 1339 L E+ +QL+EK+ ++ FTQ++ L+ +L++ E K + +LA Sbjct: 1489 DMLLAEAFSLKQQLEEKDMDIA-------GFTQKVVSLEAELQDISSQESKDEASLAKVK 1541 Query: 1340 QSSRHDCDLLREQYEEEQESKAELQ---RALSKANTEVAQWRTKYETDAIQRTEELEEAK 1396 + R +++Q EE E +Q +A + E+ + R + + R EE+EEA+ Sbjct: 1542 KQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEAR 1601 Query: 1397 KKLAQRLQAAEEHVEA--------------VNAKCASLEKTKQRLQNEVED-LMLDVERT 1441 + ++L+ E +E + K A+L R E E L D++RT Sbjct: 1602 QSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRT 1661 Query: 1442 NAACA----ALD--KKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTEL-------- 1487 A A LD K + +A+ K + EE+ A+ K +++ E+ Sbjct: 1662 KALLADAQLMLDHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQID 1721 Query: 1488 --FKIKNAYEESLDQLETLKRENKN-LQQEISDLTE-------QIAEGGKRIHELEKIKK 1537 K K A EE L +L+ K E +N L+++ D+ E +A+ + + ++ ++ Sbjct: 1722 DIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQA 1781 Query: 1538 QVEQ---EKCELQAALEEAEASLE-------------HEEGKILRIQLELNQVKSEVDRK 1581 Q+E+ EK ELQ L+ ++ +E +E KI ++ L +++V R Sbjct: 1782 QLEEANKEKQELQEKLQALQSQVEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQVKRL 1841 Query: 1582 IAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRM 1641 + +LK N ++ E + AE R + RL++++ EM R Sbjct: 1842 ----ESLASRLKENMEKLTEERDQRIAAENREKEQNKRLQRQLRDTKEEM----GELARK 1893 Query: 1642 AAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQT 1701 AEA R + ++ L+ + + L+ L + +R LQA IE+ Sbjct: 1894 EAEASRKKH-------ELEMDLESLEAANQSLQADLKLAFKRIGDLQAAIED-------- 1938 Query: 1702 ERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKA 1761 E E + + + L T K KLE D S + E+ED + ++ K Sbjct: 1939 -------EMESDENEDLINSLQDMVTKYQKRKNKLEGD-SDVDSELEDRVDGVKSWLSK- 1989 Query: 1762 KKAITDAAMMAEELKKEQDTS 1782 K + AA LK TS Sbjct: 1990 NKGPSKAASDDGSLKSSSPTS 2010 Score = 81.6 bits (200), Expect = 7e-15 Identities = 68/301 (22%), Positives = 146/301 (48%), Gaps = 11/301 (3%) Query: 1650 RNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAE 1709 RN ++ + L+ A + + +L+ +E R + L +E+ + R T E + Sbjct: 1257 RNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDAET 1316 Query: 1710 QELLDASERVQLLHTQNTSLINTKKKLETDI--------SQMQGEMEDILQEARNAEEKA 1761 E L A + ++ L TQ +L + +E ++ +++ GE++D K Sbjct: 1317 AERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDD-DAGGEWRLKY 1375 Query: 1762 KKAITDAAMMAEELKKEQDTSAHLERM-KKNMEQTVKDLQLRLDEAEQLALKGGKKQIQK 1820 ++A+ + + L++E + +E+ K+ +E+ + DLQ +E+++ AL+ KK+ Q+ Sbjct: 1376 ERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQR-ALQQLKKKCQR 1434 Query: 1821 LEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAK 1880 L A +++ + +E +Q RN E K R+ + + + + + ++ +LQ D L A+ Sbjct: 1435 LTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAE 1494 Query: 1881 VKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAESQVNKLRVKSREVHTKVISE 1940 S K+Q EE + K L+ EL++ + E+ + K++ + R++ KV + Sbjct: 1495 AFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQ 1554 Query: 1941 E 1941 E Sbjct: 1555 E 1555 Score = 56.6 bits (135), Expect = 2e-07 Identities = 68/267 (25%), Positives = 124/267 (46%), Gaps = 44/267 (16%) Query: 1676 QLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKK 1735 ++ + E + EI++LR+ LE+ E+ R EL S+R Sbjct: 1248 EVQLSEEQIRNKDEEIQQLRSKLEKAEKERN----ELRLNSDR----------------- 1286 Query: 1736 LETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKE---QDTSAHLERMKKNM 1792 LE+ IS++ E+ D RN E A + + A AE L+ E ++ + +KK M Sbjct: 1287 LESRISELTSELTD----ERNTGESASQLLD--AETAERLRAEKEMKELQTQYDALKKQM 1340 Query: 1793 E-QTVKDLQLRLDEAEQLALK------GGKKQIQKLEARVRELEG-----EVESEQKRNA 1840 E ++ ++ RL A ++ + GG+ ++ K E VRE++ + E E K Sbjct: 1341 EVMEMEVMEARLIRAAEINGEVDDDDAGGEWRL-KYERAVREVDFTKKRLQQEFEDKLEV 1399 Query: 1841 EAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLA 1900 E + R+ ERR+ +L +EE ++ + +L+ +L A+++ K E + +++ Sbjct: 1400 EQ-QNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEK 1458 Query: 1901 KFRKLQHELEEAEERADIAESQVNKLR 1927 K R+ EL +A E A + Q KL+ Sbjct: 1459 KQRRFDSELSQAHEEAQREKLQREKLQ 1485 Score = 34.7 bits (78), Expect = 0.93 Identities = 33/143 (23%), Positives = 69/143 (48%), Gaps = 6/143 (4%) Query: 1793 EQTVKDLQLRLDEAEQLALKGGKK-QIQKLEARVREL-EGEVESEQKRNA-EAVKGLRKH 1849 ++ ++DL +R + KG K KL VR L E ++ EQ RN E ++ LR Sbjct: 1210 KRKIQDLAIRCVQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKDEEIQQLRS- 1268 Query: 1850 ERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHEL 1909 ++++ + E R N RL+ + +L +++ + E A + + A+ + + E+ Sbjct: 1269 --KLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDAETAERLRAEKEM 1326 Query: 1910 EEAEERADIAESQVNKLRVKSRE 1932 +E + + D + Q+ + ++ E Sbjct: 1327 KELQTQYDALKKQMEVMEMEVME 1349 >gi|42794779 myosin 18A isoform b [Homo sapiens] Length = 2039 Score = 506 bits (1304), Expect = e-143 Identities = 428/1678 (25%), Positives = 814/1678 (48%), Gaps = 226/1678 (13%) Query: 58 GKVTVKTE-GGATLTVKDDQVFPMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIY 116 GKV VK + GA L V +D V N P D++ED+A + +L+E +VL+ L++RY A +++ Sbjct: 376 GKVRVKLDHDGAILDVDEDDVEKANAPSCDRLEDLASLVYLNESSVLHTLRQRYGASLLH 435 Query: 117 TYSGLFCVTVNPYKWLPVYKPEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSIL 176 TY+G + + P VY +V+ ++G +R++ PHI++++ AY+ ML R++QSI+ Sbjct: 436 TYAGPSLLVLGPRGAPAVYSEKVMHMFKGCRREDMAPHIYAVAQTAYRAMLMSRQDQSII 495 Query: 177 ITGESGAGKTVNTKRVIQYFATIAVTGEKKKEEITSGKIQGTLEDQIISANPLLEAFGNA 236 + G SG+GKT + + ++QY ATIA I+ K+ + Q + LLEAFGN+ Sbjct: 496 LLGSSGSGKTTSCQHLVQYLATIA--------GISGNKVFSVEKWQALYT--LLEAFGNS 545 Query: 237 KTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVVFQLKAERSYHIFYQITS-- 294 T+ N N++RF + + + F G++ASA I+T LLEK RV + +E ++++FY + + Sbjct: 546 PTIINGNATRFSQILSLDFDQAGQVASASIQTMLLEKLRVARRPASEATFNVFYYLLACG 605 Query: 295 --NKKPELIEMLLITTNPYDYPFVSQGEISVASIDDQEELMATDSAIDILGFTNEEKVSI 352 + EL L N + +++ E + +L A A+ +LG + +E+ + Sbjct: 606 DGTLRTELHLNHLAENNVFGIVPLAKPEEKQKAAQQFSKLQA---AMKVLGISPDEQKAC 662 Query: 353 YKLTGAVMHYGNLKFKQKQREEQAEPDGT-EVADKAAYLQSLNSADLLKALCYPRVKVG- 410 + + A+ H G ++ E + E A KAAYL + +L A+ + K G Sbjct: 663 WFILAAIYHLGAAGATKEAAEAGRKQFARHEWAQKAAYLLGCSLEELSSAIFKHQHKGGT 722 Query: 411 ---NEYVTKGQTVEQVSNAVG----------ALAKAVYEKMFLWMVARINQQLDTKQPRQ 457 + +G + + G +A +Y ++F +V+ +N+ L + Q Sbjct: 723 LQRSTSFRQGPEESGLGDGTGPKLSALECLEGMAAGLYSELFTLLVSLVNRALKSSQHSL 782 Query: 458 YFIGVLDIAGFEIFDFN------SLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEW 511 + ++D GF+ + S E+LC N+T ++LQ+ F+ FV E E YK+E IE Sbjct: 783 CSMMIVDTPGFQNPEQGGSARGASFEELCHNYTQDRLQRLFHERTFVQELERYKEENIEL 842 Query: 512 TFIDF---------GMDLAACIELI------EKPMGIFSILEEECMFPKATDTSFKNKLY 556 F D +D A+ L+ ++ G+ +LEEE + P A++ + +L+ Sbjct: 843 AFDDLEPPTDDSVAAVDQASHQSLVRSLARTDEARGLLWLLEEEALVPGASEDTLLERLF 902 Query: 557 DQHLGKSAN--FQKPKVVKGKAEAHFALIHYAGV--VDYNITGWLEKNK-DPLNETVVGL 611 + + + Q P + K HF L H G V+YN+TGWL K +P + L Sbjct: 903 SYYGPQEGDKKGQSPLLHSSKPH-HFLLGHSHGTNWVEYNVTGWLNYTKQNPATQNAPRL 961 Query: 612 YQKSAMKTLAQLFSG----AQTAEGEGAG--GGAKKGGKKKGSSFQT----VSALFRENL 661 Q S K ++ LF G A G AG GG++ ++ S +T ++A+ +++L Sbjct: 962 LQDSQKKIISNLFLGRAGSATVLSGSIAGLEGGSQLALRRATSMRKTFTTGMAAVKKKSL 1021 Query: 662 --------NKLMTNLRSTHPHFVRCIIP--------------------NETKTPGA---- 689 + L+ ++ + HFV C +P +E P Sbjct: 1022 CIQMKLQVDALIDTIKKSKLHFVHCFLPVAEGWAGEPRSASSRRVSSSSELDLPSGDHCE 1081 Query: 690 -----MEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQ---- 740 ++ L+ QLR + +L+ +R+ R+G+P +++++F++R+ VL + Sbjct: 1082 AGLLQLDVPLLRTQLRGSRLLDAMRMYRQGYPDHMVFSEFRRRFDVLAPHLTKKHGRNYI 1141 Query: 741 FIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDDKLAQLITRTQARCRG 800 +D ++A E+LL +D++ + G ++VFF+AG L LEE RD++ ++ +T QA CRG Sbjct: 1142 VVDERRAVEELLECLDLEKSSCCMGLSRVFFRAGTLARLEEQRDEQTSRNLTLFQAACRG 1201 Query: 801 FLARVEYQRMVERREAIFCIQYNIRSFMNVKHWPWMKLFFKIKPLLKSAETEKEMATMKE 860 +LAR +++ + AI C+Q NI+ VK WPW KLF ++PL++ +E+++ E Sbjct: 1202 YLARQHFKKRKIQDLAIRCVQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKDE 1261 Query: 861 EFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCDQLIKTKIQ 920 E Q+++ +L K+E +R EL L ++L ++ E A + D +++ Sbjct: 1262 EIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDAETAERLR 1321 Query: 921 LEAKIKEVTER--AEDEEEINAELTAKKRKLEDECSELKKDIDDLEL---TLAKVEKEKH 975 E ++KE+ + A ++ E+ + +L +E+ ++DD + K E+ Sbjct: 1322 AEKEMKELQTQYDALKKQMEVMEMEVMEARL-IRAAEINGEVDDDDAGGEWRLKYERAVR 1380 Query: 976 ATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDK----VNTLTKAKI 1031 + K L +E ++ + + K+ L ++ L DLQA+ ++ + L K Sbjct: 1381 EVDFTKKRLQQE---FEDKLEVEQQNKRQL----ERRLGDLQADSEESQRALQQLKKKCQ 1433 Query: 1032 KLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEF 1091 +L ++ D + LE ++ +LE+ +R+ + +L A E + + EK Q ++ ++K+ Sbjct: 1434 RLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHE---EAQREKLQREKLQREKDM 1490 Query: 1092 ---EISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRE 1148 E +L+ ++E++ +K+ L+A ++++ + + AS AK +KQ DL + Sbjct: 1491 LLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAK 1550 Query: 1149 LEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAE 1208 +++ E L+E G I+M LE+A L+ E +R+ H+ + Sbjct: 1551 VKDQEEELDEQAGT----IQM--------------LEQAKLRLEMEMERMRQTHSKEMES 1592 Query: 1209 LGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSK 1268 E++ + +Q +K+ +M++++++ + + V + K LE TL DQ++ + Sbjct: 1593 RDEEV---EEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVN--RRD 1647 Query: 1269 EEEQQRLINDLTAQRGRL----------------QTESGEFSRQLDEKEALVSQLSRGKQ 1312 E ++RL DL + L + E + QL+E E + + ++ Sbjct: 1648 FESEKRLRKDLKRTKALLADAQLMLDHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARK 1707 Query: 1313 AFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQR----ALS 1368 A +IE+L Q+++ KAK AL L + + + ++ + EE+QE EL + A++ Sbjct: 1708 AMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVA 1767 Query: 1369 KANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVE-----AVNAKCASLEKT 1423 +A+ ++AQ D + EE + K++L ++LQA + VE V+ S ++ Sbjct: 1768 QASRDLAQ-----INDLQAQLEEANKEKQELQEKLQALQSQVEFLEQSMVDKSLVSRQEA 1822 Query: 1424 KQR-LQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARS 1482 K R L+ +E V+R + + L + N +K+ E Q+ + E E +++ Sbjct: 1823 KIRELETRLEFERTQVKRLESLASRL---KENMEKLTEERDQRIAAENREKEQNKR---- 1875 Query: 1483 LGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQE 1542 L+R+ ++ ++E+ +L + AE ++ HELE + +E Sbjct: 1876 ---------------------LQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAA 1914 Query: 1543 KCELQAALE-------EAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLK 1593 LQA L+ + +A++E E L ++ S+VD +E ++ +D +K Sbjct: 1915 NQSLQADLKLAFKRIGDLQAAIEDEMESDENEDLINSEGDSDVD---SELEDRVDGVK 1969 Score = 186 bits (471), Expect = 3e-46 Identities = 158/694 (22%), Positives = 330/694 (47%), Gaps = 61/694 (8%) Query: 1252 EKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQL-DEKEA--LVSQLS 1308 E+ R ++++ +L+SK E+ ++ N+L RL++ E + +L DE+ SQL Sbjct: 1253 EEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLL 1312 Query: 1309 RGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQY----EEEQESKAELQ 1364 + A + E+ ++L+ + A ++ + L+R ++ ++ E + Sbjct: 1313 DAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWR 1372 Query: 1365 RALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTK 1424 +A EV + + + + + E ++ K++L +RL + E L+K Sbjct: 1373 LKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKC 1432 Query: 1425 QRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLG 1484 QRL E++D L +E L+KKQR FD L++ ++ + + E Q+E L Sbjct: 1433 QRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLL 1492 Query: 1485 TELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKC 1544 E F +K EE + ++ +L+ E+ D++ Q K L K+KKQ+ Sbjct: 1493 AEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQ---ESKDEASLAKVKKQLR---- 1545 Query: 1545 ELQAALEEAEASLEHEEGKI-------LRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHI 1597 +L+A +++ E L+ + G I LR+++E+ +++ +++ +DEE+++ +++ Sbjct: 1546 DLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQ 1605 Query: 1598 RIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALR-NYRNTQGIL 1656 + ++ M+ L+ E + +R K+++EG L + Q+N + + + LR + + T+ +L Sbjct: 1606 KKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALL 1665 Query: 1657 KDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDAS 1716 D Q+ LD L++ K ++A L+ ++EE T ++RK E E+ D Sbjct: 1666 ADAQLMLDH-LKNSAPSKREIAQ-------LKNQLEESEFTCAAAVKARKAMEVEIED-- 1715 Query: 1717 ERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELK 1776 LH Q + K LE +S++Q E +I +E M E +K Sbjct: 1716 -----LHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQED----------MNELMK 1760 Query: 1777 KEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQ 1836 K + A + + +++ Q + DLQ +L+EA K+ Q+L+ +++ L+ +VE + Sbjct: 1761 KHK---AAVAQASRDLAQ-INDLQAQLEEA--------NKEKQELQEKLQALQSQVEFLE 1808 Query: 1837 KRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSN 1896 + + + + E +++EL + E +R + RL+ L +L+ ++ + ++ N Sbjct: 1809 QSMVDK-SLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEERDQRIAAEN 1867 Query: 1897 TNLAKFRKLQHELEEA-EERADIAESQVNKLRVK 1929 + ++LQ +L + EE ++A + R K Sbjct: 1868 REKEQNKRLQRQLRDTKEEMGELARKEAEASRKK 1901 Score = 147 bits (372), Expect = 8e-35 Identities = 185/832 (22%), Positives = 372/832 (44%), Gaps = 121/832 (14%) Query: 945 KKRKLED--ECSELKKDIDDLEL--------TLAKVEKEKHATENKVKNLTEEMAGLDET 994 ++R +E+ EC +L+K + L TLA++E+++ E +NLT A Sbjct: 1145 ERRAVEELLECLDLEKSSCCMGLSRVFFRAGTLARLEEQRD--EQTSRNLTLFQAACRGY 1202 Query: 995 IAKLTKEKKALQEAH----QQTLDDLQAEED----KVNTLTKAKIKLEQQVDDLEGSLEQ 1046 +A+ +K+ +Q+ Q+ + + +D K+ T + I+++ + + E+ Sbjct: 1203 LARQHFKKRKIQDLAIRCVQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKDEE 1262 Query: 1047 EKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQAL 1106 ++LR LE+A+++ +L+L + + E+ +L +L + + ++ E A Sbjct: 1263 IQQLRSKLEKAEKE-RNELRLNSDRL---ESRISELTSELTDERNTGESASQLLDAETAE 1318 Query: 1107 GIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRS-DLSRELEEISERLEEAGGATSA 1165 ++ +K++KELQ + + L++++E +A R+ +++ E+++ ++AGG Sbjct: 1319 RLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDD-----DDAGGEWRL 1373 Query: 1166 QIEMNKKREAEFQKMR--RDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKL 1223 + E RE +F K R ++ E+ + L ++ D A+ E QR Q+L Sbjct: 1374 KYE-RAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEES----QRALQQL 1428 Query: 1224 EKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQR 1283 +K+ + E+ D ++E LEK R + +LS+ + + ++ L ++ Sbjct: 1429 KKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREK 1488 Query: 1284 GRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEE----EIKAKNALAHAL 1339 L E+ +QL+EK+ ++ FTQ++ L+ +L++ E K + +LA Sbjct: 1489 DMLLAEAFSLKQQLEEKDMDIA-------GFTQKVVSLEAELQDISSQESKDEASLAKVK 1541 Query: 1340 QSSRHDCDLLREQYEEEQESKAELQ---RALSKANTEVAQWRTKYETDAIQRTEELEEAK 1396 + R +++Q EE E +Q +A + E+ + R + + R EE+EEA+ Sbjct: 1542 KQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEAR 1601 Query: 1397 KKLAQRLQAAEEHVEA--------------VNAKCASLEKTKQRLQNEVED-LMLDVERT 1441 + ++L+ E +E + K A+L R E E L D++RT Sbjct: 1602 QSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRT 1661 Query: 1442 NAACA----ALD--KKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTEL-------- 1487 A A LD K + +A+ K + EE+ A+ K +++ E+ Sbjct: 1662 KALLADAQLMLDHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQID 1721 Query: 1488 --FKIKNAYEESLDQLETLKRENKN-LQQEISDLTE-------QIAEGGKRIHELEKIKK 1537 K K A EE L +L+ K E +N L+++ D+ E +A+ + + ++ ++ Sbjct: 1722 DIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQA 1781 Query: 1538 QVEQ---EKCELQAALEEAEASLE-------------HEEGKILRIQLELNQVKSEVDRK 1581 Q+E+ EK ELQ L+ ++ +E +E KI ++ L +++V R Sbjct: 1782 QLEEANKEKQELQEKLQALQSQVEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQVKRL 1841 Query: 1582 IAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRM 1641 + +LK N ++ E + AE R + RL++++ EM R Sbjct: 1842 ----ESLASRLKENMEKLTEERDQRIAAENREKEQNKRLQRQLRDTKEEM----GELARK 1893 Query: 1642 AAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEE 1693 AEA R + ++ L+ + + L+ L + +R LQA IE+ Sbjct: 1894 EAEASRKKH-------ELEMDLESLEAANQSLQADLKLAFKRIGDLQAAIED 1938 Score = 81.6 bits (200), Expect = 7e-15 Identities = 68/301 (22%), Positives = 146/301 (48%), Gaps = 11/301 (3%) Query: 1650 RNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAE 1709 RN ++ + L+ A + + +L+ +E R + L +E+ + R T E + Sbjct: 1257 RNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDAET 1316 Query: 1710 QELLDASERVQLLHTQNTSLINTKKKLETDI--------SQMQGEMEDILQEARNAEEKA 1761 E L A + ++ L TQ +L + +E ++ +++ GE++D K Sbjct: 1317 AERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDD-DAGGEWRLKY 1375 Query: 1762 KKAITDAAMMAEELKKEQDTSAHLERM-KKNMEQTVKDLQLRLDEAEQLALKGGKKQIQK 1820 ++A+ + + L++E + +E+ K+ +E+ + DLQ +E+++ AL+ KK+ Q+ Sbjct: 1376 ERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQR-ALQQLKKKCQR 1434 Query: 1821 LEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAK 1880 L A +++ + +E +Q RN E K R+ + + + + + ++ +LQ D L A+ Sbjct: 1435 LTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAE 1494 Query: 1881 VKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAESQVNKLRVKSREVHTKVISE 1940 S K+Q EE + K L+ EL++ + E+ + K++ + R++ KV + Sbjct: 1495 AFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQ 1554 Query: 1941 E 1941 E Sbjct: 1555 E 1555 Score = 56.6 bits (135), Expect = 2e-07 Identities = 68/267 (25%), Positives = 124/267 (46%), Gaps = 44/267 (16%) Query: 1676 QLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKK 1735 ++ + E + EI++LR+ LE+ E+ R EL S+R Sbjct: 1248 EVQLSEEQIRNKDEEIQQLRSKLEKAEKERN----ELRLNSDR----------------- 1286 Query: 1736 LETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKE---QDTSAHLERMKKNM 1792 LE+ IS++ E+ D RN E A + + A AE L+ E ++ + +KK M Sbjct: 1287 LESRISELTSELTD----ERNTGESASQLLD--AETAERLRAEKEMKELQTQYDALKKQM 1340 Query: 1793 E-QTVKDLQLRLDEAEQLALK------GGKKQIQKLEARVRELEG-----EVESEQKRNA 1840 E ++ ++ RL A ++ + GG+ ++ K E VRE++ + E E K Sbjct: 1341 EVMEMEVMEARLIRAAEINGEVDDDDAGGEWRL-KYERAVREVDFTKKRLQQEFEDKLEV 1399 Query: 1841 EAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLA 1900 E + R+ ERR+ +L +EE ++ + +L+ +L A+++ K E + +++ Sbjct: 1400 EQ-QNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEK 1458 Query: 1901 KFRKLQHELEEAEERADIAESQVNKLR 1927 K R+ EL +A E A + Q KL+ Sbjct: 1459 KQRRFDSELSQAHEEAQREKLQREKLQ 1485 Score = 34.7 bits (78), Expect = 0.93 Identities = 33/143 (23%), Positives = 69/143 (48%), Gaps = 6/143 (4%) Query: 1793 EQTVKDLQLRLDEAEQLALKGGKK-QIQKLEARVREL-EGEVESEQKRNA-EAVKGLRKH 1849 ++ ++DL +R + KG K KL VR L E ++ EQ RN E ++ LR Sbjct: 1210 KRKIQDLAIRCVQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKDEEIQQLRS- 1268 Query: 1850 ERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHEL 1909 ++++ + E R N RL+ + +L +++ + E A + + A+ + + E+ Sbjct: 1269 --KLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDAETAERLRAEKEM 1326 Query: 1910 EEAEERADIAESQVNKLRVKSRE 1932 +E + + D + Q+ + ++ E Sbjct: 1327 KELQTQYDALKKQMEVMEMEVME 1349 >gi|154354979 myosin X [Homo sapiens] Length = 2058 Score = 491 bits (1265), Expect = e-138 Identities = 330/1058 (31%), Positives = 562/1058 (53%), Gaps = 59/1058 (5%) Query: 32 FDAKTSVFVAEPKESFVKGTIQSREGGKVTVKTEGGATLTVKDD-----QVFPMNPPKYD 86 F T V++ E + F T+ S G V +T+ G T K +V M+P + Sbjct: 5 FTEGTRVWLRENGQHF-PSTVNSCAEGIVVFRTDYGQVFTYKQSTITHQKVTAMHPTNEE 63 Query: 87 KIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLP-VYKPEVVTAYRG 145 ++DMA +T LH +++YNL +RY IYTY G +VNPY+ + +Y+P + Y Sbjct: 64 GVDDMASLTELHGGSIMYNLFQRYKRNQIYTYIGSILASVNPYQPIAGLYEPATMEQYSR 123 Query: 146 KKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEK 205 + E PPHIF+I++ Y+ + +NQ ILI+GESGAGKT +TK ++++ + I+ + Sbjct: 124 RHLGELPPHIFAIANECYRCLWKRHDNQCILISGESGAGKTESTKLILKFLSVIS----Q 179 Query: 206 KKEEITSGKIQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASAD 265 + E++ + +E I+ ++P++EAFGNAKTV N+NSSRFGKF++++ G + Sbjct: 180 QSLELSLKEKTSCVERAILESSPIMEAFGNAKTVYNNNSSRFGKFVQLNICQKGNIQGGR 239 Query: 266 IETYLLEKSRVVFQLKAERSYHIFYQITSNKKPELIEMLLITTNPYDYPFVSQ-GEISVA 324 I YLLEK+RVV Q ER+YHIFY + + + E E ++T P +Y +++Q G + Sbjct: 240 IVDYLLEKNRVVRQNPGERNYHIFYALLAGLEHEEREEFYLST-PENYHYLNQSGCVEDK 298 Query: 325 SIDDQEELMATDSAIDILGFTNEEKVSIYKLTGAVMHYGNLKFKQKQREEQAEPDGTEVA 384 +I DQE +A+D++ F+ EE + +L ++H GN++F A+ Sbjct: 299 TISDQESFREVITAMDVMQFSKEEVREVSRLLAGILHLGNIEF---ITAGGAQVSFKTAL 355 Query: 385 DKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTVEQVSNAVGALAKAVYEKMFLWMVA 444 ++A L L+ L AL + + E + V+Q ++ +LA A+Y F W++ Sbjct: 356 GRSAELLGLDPTQLTDALTQRSMFLRGEEILTPLNVQQAVDSRDSLAMALYACCFEWVIK 415 Query: 445 RINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEY 504 +IN ++ + + IG+LDI GFE F+ N EQ IN+ NEKLQ++FN H+F LEQ EY Sbjct: 416 KINSRIKGNEDFK-SIGILDIFGFENFEVNHFEQFNINYANEKLQEYFNKHIFSLEQLEY 474 Query: 505 KKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLYDQHLGKSA 564 +EG+ W ID+ +D C++LIEK +G+ +++ EE FP+ATD++ KL+ QH + Sbjct: 475 SREGLVWEDIDW-IDNGECLDLIEKKLGLLALINEESHFPQATDSTLLEKLHSQH-ANNH 532 Query: 565 NFQKPKVVKGKAEAHFALIHYAGVVDYNITGWLEKNKDPLNETVVGLYQKSAMKTLAQLF 624 + KP+V A +F + HYAG V Y++ G LEKN+D + ++ L ++S + LF Sbjct: 533 FYVKPRV----AVNNFGVKHYAGEVQYDVRGILEKNRDTFRDDLLNLLRESRFDFIYDLF 588 Query: 625 SGAQTAEGEGAGGGAKKGGKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPNET 684 + + K G K + TVS+ F+++L+ LM L S++P FVRCI PN Sbjct: 589 EHVSSRNNQDT---LKCGSKHRR---PTVSSQFKDSLHSLMATLSSSNPFFVRCIKPNMQ 642 Query: 685 KTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNAS-AIPEGQFID 743 K P + +VL+QLR +G+LE +RI + G+ R + DF +RYKVL + A+PE D Sbjct: 643 KMPDQFDQAVVLNQLRYSGMLETVRIRKAGYAVRRPFQDFYKRYKVLMRNLALPE----D 698 Query: 744 SKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDDKLAQLITRTQARCRGFLA 803 + LL D +++++ G TKVF + L LE+ R+++++ +A GFLA Sbjct: 699 VRGKCTSLLQLYDASNSEWQLGKTKVFLRESLEQKLEKRREEEVSHAAMVIRAHVLGFLA 758 Query: 804 RVEYQRMVERREAIFCIQYNIRSFMNVKHWPWMKLFFKIKPLLKSAETEKEMATMKEEFQ 863 R +Y++++ + IQ N R+F+ + F +K + + + ++ Sbjct: 759 RKQYRKVL---YCVVIIQKNYRAFL------LRRRFLHLKKAAIVFQKQLRGQIARRVYR 809 Query: 864 KIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCDQLIKTKIQLEA 923 ++ E + E K+K+ EE EK + + + +AE R Q +T+ Q E Sbjct: 810 QLLAEKREQEEKKKQEEE-------EKKKREEEERERERERREAELRAQQEEETRKQQEL 862 Query: 924 KIKEVTERAEDEEEINAEL-TAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVK 982 E ++++ E E+ EL K+ K +E L+K+I+DL+ K ++E TE ++ Sbjct: 863 ---EALQKSQKEAELTRELEKQKENKQVEEILRLEKEIEDLQ--RMKEQQELSLTEASLQ 917 Query: 983 NLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEG 1042 L E D+ + +L +E + ++L+ + +E N + E + E Sbjct: 918 KLQERR---DQELRRLEEEACRAAQEFLESLNFDEIDECVRNIERSLSVGSEFSSELAES 974 Query: 1043 SLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQ 1080 + E++ + +++ + ++ D N + Sbjct: 975 ACEEKPNFNFSQPYPEEEVDEGFEADDDAFKDSPNPSE 1012 Score = 48.1 bits (113), Expect = 8e-05 Identities = 63/252 (25%), Positives = 121/252 (48%), Gaps = 32/252 (12%) Query: 904 LADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDL 963 L DA QL KTK+ L +++ E+ +EE +A + + L +K + Sbjct: 709 LYDASNSEWQLGKTKVFLRESLEQKLEKRREEEVSHAAMVIRAHVLGFLA---RKQYRKV 765 Query: 964 ELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKV 1023 + ++K A + + L + A + + + + + ++Q L + + +E+K Sbjct: 766 LYCVVIIQKNYRAFLLRRRFLHLKKAAI---VFQKQLRGQIARRVYRQLLAEKREQEEKK 822 Query: 1024 NTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLD 1083 K E++ E++K+ + ER + + E +L+ QE E KQQ Sbjct: 823 --------KQEEE--------EKKKREEEERERERERREAELRAQQEE----ETRKQQEL 862 Query: 1084 EKLKK--KEFEISN-LQSKIEDEQALGI-QLQKKIKELQARIEELEEEIEAERASRAKAE 1139 E L+K KE E++ L+ + E++Q I +L+K+I++LQ R++E ++E+ AS K + Sbjct: 863 EALQKSQKEAELTRELEKQKENKQVEEILRLEKEIEDLQ-RMKE-QQELSLTEASLQKLQ 920 Query: 1140 KQRSDLSRELEE 1151 ++R R LEE Sbjct: 921 ERRDQELRRLEE 932 Score = 45.8 bits (107), Expect = 4e-04 Identities = 49/166 (29%), Positives = 82/166 (49%), Gaps = 10/166 (6%) Query: 1293 FSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQ 1352 F +QL + + ++ R A ++ EE K+Q EEE K + + R + + LR Q Sbjct: 795 FQKQL--RGQIARRVYRQLLAEKREQEEKKKQEEEEKKKREEEERERERERREAE-LRAQ 851 Query: 1353 YEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEA 1412 EEE + EL+ AL K+ E R + ++ EE+ +K++ + LQ +E E Sbjct: 852 QEEETRKQQELE-ALQKSQKEAELTRELEKQKENKQVEEILRLEKEI-EDLQRMKEQQE- 908 Query: 1413 VNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKI 1458 ++ ASL+K ++R E+ L+ E AA L+ NFD+I Sbjct: 909 LSLTEASLQKLQERRDQELR--RLEEEACRAAQEFLE--SLNFDEI 950 Score = 44.3 bits (103), Expect = 0.001 Identities = 45/193 (23%), Positives = 84/193 (43%), Gaps = 17/193 (8%) Query: 1047 EKKLRMDL-ERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQA 1105 +K+LR + R R+L + + +E E EK++ +E+ +++E E + + + E+ Sbjct: 796 QKQLRGQIARRVYRQLLAEKREQEEKKKQEEEEKKKREEEERERERERREAELRAQQEEE 855 Query: 1106 LGIQLQKKIKELQARIEELEEEIEAERASRA-----KAEKQRSDLSRELEEISERLEEAG 1160 Q + + + + EL E+E ++ ++ + EK+ DL R E+ L EA Sbjct: 856 TRKQQELEALQKSQKEAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQELSLTEA- 914 Query: 1161 GATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVK 1220 + K +E Q++RR EEA A L + D + E I+ V Sbjct: 915 -------SLQKLQERRDQELRRLEEEAC---RAAQEFLESLNFDEIDECVRNIERSLSVG 964 Query: 1221 QKLEKEKSEMKME 1233 + E +E E Sbjct: 965 SEFSSELAESACE 977 Score = 42.7 bits (99), Expect = 0.003 Identities = 32/125 (25%), Positives = 62/125 (49%), Gaps = 10/125 (8%) Query: 1822 EARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKV 1881 E R +E + + E E+K+ E + R+ ERR EL Q EE+ R Q ++ LQ Sbjct: 814 EKREQEEKKKQEEEEKKKREEEERERERERREAELRAQQEEE----TRKQQELEALQKSQ 869 Query: 1882 KSYKRQAEEAEEQSNTNLAKFRKLQHELEE-----AEERADIAESQVNKLRVKSREVHTK 1936 K + E +++ N + + +L+ E+E+ ++ + E+ + KL+ + R+ + Sbjct: 870 KEAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQELSLTEASLQKLQ-ERRDQELR 928 Query: 1937 VISEE 1941 + EE Sbjct: 929 RLEEE 933 Score = 37.7 bits (86), Expect = 0.11 Identities = 37/179 (20%), Positives = 84/179 (46%), Gaps = 22/179 (12%) Query: 1718 RVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKK 1777 R + LH + +++ +K+L I++ +L E R EEK K+ EE KK Sbjct: 782 RRRFLHLKKAAIV-FQKQLRGQIARRV--YRQLLAEKREQEEKKKQE-------EEEKKK 831 Query: 1778 EQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQK 1837 ++ ER ++ E LR + E+ +++++ L+ +E E E E++ Sbjct: 832 REEEERERERERREAE-------LRAQQEEETR---KQQELEALQKSQKEAELTRELEKQ 881 Query: 1838 RNAEAVKGLRKHERRVKELTYQTEEDRKNILR--LQDLVDKLQAKVKSYKRQAEEAEEQ 1894 + + V+ + + E+ +++L E+ ++ LQ L ++ +++ + +A A ++ Sbjct: 882 KENKQVEEILRLEKEIEDLQRMKEQQELSLTEASLQKLQERRDQELRRLEEEACRAAQE 940 Score = 36.6 bits (83), Expect = 0.25 Identities = 46/175 (26%), Positives = 80/175 (45%), Gaps = 21/175 (12%) Query: 1217 QRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLI 1276 +RV ++L EK E + + E K K E+ R E + +EL++++EE+ R Sbjct: 805 RRVYRQLLAEKREQEEK-----KKQEEEEKKKREEEERERERERREAELRAQQEEETRKQ 859 Query: 1277 NDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALA 1336 +L A + + Q E+ E +R+L+ KQ +Q+EE+ R LE+EI+ + Sbjct: 860 QELEALQ-KSQKEA-ELTRELE------------KQKENKQVEEILR-LEKEIEDLQRMK 904 Query: 1337 HALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEE 1391 + S + L + Q +QE + L+ +A E + E D R E Sbjct: 905 EQQELSLTEASLQKLQERRDQELR-RLEEEACRAAQEFLESLNFDEIDECVRNIE 958 Score = 36.6 bits (83), Expect = 0.25 Identities = 37/147 (25%), Positives = 74/147 (50%), Gaps = 18/147 (12%) Query: 1449 DKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKREN 1508 +KK+R + E +++ E AEL A Q+E EL ++ + +E+ + L+++ Sbjct: 828 EKKKREEE----ERERERERREAELRAQQEEETRKQQELEALQKSQKEA-ELTRELEKQK 882 Query: 1509 KNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQ 1568 +N Q E+I K I +L+++K+Q QE +A+L++ + E + ++ R++ Sbjct: 883 ENKQ------VEEILRLEKEIEDLQRMKEQ--QELSLTEASLQKLQ---ERRDQELRRLE 931 Query: 1569 LELNQVKSEVDRKIAEKDEEIDQLKRN 1595 E + E + +EID+ RN Sbjct: 932 EEACRAAQEFLESL--NFDEIDECVRN 956 Score = 36.2 bits (82), Expect = 0.32 Identities = 39/156 (25%), Positives = 75/156 (48%), Gaps = 35/156 (22%) Query: 1261 QLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEE 1320 Q E K K EE++R + + L+ + E +R+ E EAL Q S+ + T+++E+ Sbjct: 824 QEEEEKKKREEEERE-RERERREAELRAQQEEETRKQQELEAL--QKSQKEAELTRELEK 880 Query: 1321 LK--RQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWR 1378 K +Q+EE ++ L ++ E+ Q K + + +L++A+ + Q R Sbjct: 881 QKENKQVEEILR------------------LEKEIEDLQRMKEQQELSLTEASLQKLQER 922 Query: 1379 TKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVN 1414 E ++R EE + +AA+E +E++N Sbjct: 923 RDQE---LRRLEE---------EACRAAQEFLESLN 946 Score = 33.1 bits (74), Expect = 2.7 Identities = 36/117 (30%), Positives = 60/117 (51%), Gaps = 11/117 (9%) Query: 1518 LTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSE 1577 L E+ + K+ E E+ KK+ E+E+ E + EAE + EE R Q EL ++ Sbjct: 812 LAEKREQEEKKKQEEEE-KKKREEEERERERERREAELRAQQEEE--TRKQQELEALQK- 867 Query: 1578 VDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQ 1634 +K AE E+++ K N ++ E ++ L+ EI D R+K++ E L E +Q Sbjct: 868 -SQKEAELTRELEKQKENK-QVEEILR--LEKEI---EDLQRMKEQQELSLTEASLQ 917 >gi|189083802 myosin VIIA isoform 2 [Homo sapiens] Length = 2175 Score = 481 bits (1238), Expect = e-135 Identities = 326/926 (35%), Positives = 489/926 (52%), Gaps = 70/926 (7%) Query: 79 PMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYKPE 138 PM+P +EDM + L+E +L NL RY +IYTY+G V VNPY+ L +Y PE Sbjct: 58 PMHPTSVHGVEDMIRLGDLNEAGILRNLLIRYRDHLIYTYTGSILVAVNPYQLLSIYSPE 117 Query: 139 VVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFAT 198 + Y KK E PPHIF+I+DN Y M + +Q +I+GESGAGKT +TK ++Q+ A Sbjct: 118 HIRQYTNKKIGEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFLA- 176 Query: 199 IAVTGEKKKEEITSGKIQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTT 258 A++G+ +E Q++ A P+LEAFGNAKT+RNDNSSRFGK+I IHF Sbjct: 177 -AISGQ-----------HSWIEQQVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKR 224 Query: 259 GKLASADIETYLLEKSRVVFQLKAERSYHIFYQITSNKKPELIEMLLITTNPYDYPFVSQ 318 G + A IE YLLEKSRV Q ER+YH+FY + + + L + DY +++ Sbjct: 225 GAIEGAKIEQYLLEKSRVCRQALDERNYHVFYCMLEGMSEDQKKKLGL-GQASDYNYLAM 283 Query: 319 GE-ISVASIDDQEELMATDSAIDILGFTNEEKVSIYKLTGAVMHYGNLKFKQKQRE--EQ 375 G I+ D +E SA+ +L FT+ E I KL A++H GNL+++ + E + Sbjct: 284 GNCITCEGRVDSQEYANIRSAMKVLMFTDTENWEISKLLAAILHLGNLQYEARTFENLDA 343 Query: 376 AEPDGTEVADKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTVEQVSNAVGALAKAVY 435 E + AA L +N DL+ L + E V+ + EQ + A K +Y Sbjct: 344 CEVLFSPSLATAASLLEVNPPDLMSCLTSRTLITRGETVSTPLSREQALDVRDAFVKGIY 403 Query: 436 EKMFLWMVARINQQL------DTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQ 489 ++F+W+V +IN + D K R+ IG+LDI GFE F NS EQLCINF NE LQ Sbjct: 404 GRLFVWIVDKINAAIYKPPSQDVKNSRR-SIGLLDIFGFENFAVNSFEQLCINFANEHLQ 462 Query: 490 QFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDT 549 QFF H+F LEQEEY E I+W I+F + A + KPM I S+++EE FPK TDT Sbjct: 463 QFFVRHVFKLEQEEYDLESIDWLHIEFTDNQDALDMIANKPMNIISLIDEESKFPKGTDT 522 Query: 550 SFKNKLYDQHLGKSANFQKPKVVKGKAEAHFALIHYAGVVDYNITGWLEKNKDPLNETVV 609 + +KL QH +AN+ P K E F + H+AG+V Y G+LEKN+D L+ ++ Sbjct: 523 TMLHKLNSQH-KLNANYIPP---KNNHETQFGINHFAGIVYYETQGFLEKNRDTLHGDII 578 Query: 610 GLYQKSAMKTLAQLFSGAQTAEGEGAGGGAKKGGKKKGSSFQTVSALFRENLNKLMTNLR 669 L S K + Q+F A A G +K+ T+S+ F+ +L LM L Sbjct: 579 QLVHSSRNKFIKQIFQ-ADVAMGAET--------RKRS---PTLSSQFKRSLELLMRTLG 626 Query: 670 STHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYK 729 + P FVRCI PNE K P + L + QLR +G++E IRI R G+P R + +F +RY+ Sbjct: 627 ACQPFFVRCIKPNEFKKPMLFDRHLCVRQLRYSGMMETIRIRRAGYPIRYSFVEFVERYR 686 Query: 730 VLNASAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDDKLAQ 789 VL P + D + +++ ++ H ++ G TK+F K LLE RD + Sbjct: 687 VLLPGVKPAYKQGDLRGTCQRMAEAVLGTHDDWQIGKTKIFLKDHHDMLLEVERDKAITD 746 Query: 790 LITRTQARCRGFLARVEYQRMVERREAIFCIQYNIRSFMNVKHWPWMKL-FFKIKPLLKS 848 + Q RGF R + ++ + A IQ + R K++ M+L F +++ L +S Sbjct: 747 RVILLQKVIRGFKDRSNFLKL---KNAATLIQRHWRGHNCRKNYGLMRLGFLRLQALHRS 803 Query: 849 AETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAE 908 + ++ ++ + + ++ RK ++ + L VQA A G+ Sbjct: 804 RKLHQQYRLARQRIIQFQAR-CRAYLVRKAFRHRLWAV--------LTVQAYARGM--IA 852 Query: 909 ERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKK------RKLEDECSELKKDIDD 962 R Q ++ + + +++ R +EE++ E++AKK RK ++ ++L ++ + Sbjct: 853 RRLHQRLRAEYLWRLEAEKM--RLAEEEKLRKEMSAKKAKEEAERKHQERLAQLAREDAE 910 Query: 963 LELTLAKVEKEKHATENKVKNLTEEM 988 EL KEK A K K L E+M Sbjct: 911 REL------KEKEAARRK-KELLEQM 929 >gi|189083800 myosin VIIA isoform 3 [Homo sapiens] Length = 1204 Score = 481 bits (1238), Expect = e-135 Identities = 326/926 (35%), Positives = 489/926 (52%), Gaps = 70/926 (7%) Query: 79 PMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYKPE 138 PM+P +EDM + L+E +L NL RY +IYTY+G V VNPY+ L +Y PE Sbjct: 58 PMHPTSVHGVEDMIRLGDLNEAGILRNLLIRYRDHLIYTYTGSILVAVNPYQLLSIYSPE 117 Query: 139 VVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFAT 198 + Y KK E PPHIF+I+DN Y M + +Q +I+GESGAGKT +TK ++Q+ A Sbjct: 118 HIRQYTNKKIGEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFLA- 176 Query: 199 IAVTGEKKKEEITSGKIQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTT 258 A++G+ +E Q++ A P+LEAFGNAKT+RNDNSSRFGK+I IHF Sbjct: 177 -AISGQ-----------HSWIEQQVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKR 224 Query: 259 GKLASADIETYLLEKSRVVFQLKAERSYHIFYQITSNKKPELIEMLLITTNPYDYPFVSQ 318 G + A IE YLLEKSRV Q ER+YH+FY + + + L + DY +++ Sbjct: 225 GAIEGAKIEQYLLEKSRVCRQALDERNYHVFYCMLEGMSEDQKKKLGL-GQASDYNYLAM 283 Query: 319 GE-ISVASIDDQEELMATDSAIDILGFTNEEKVSIYKLTGAVMHYGNLKFKQKQRE--EQ 375 G I+ D +E SA+ +L FT+ E I KL A++H GNL+++ + E + Sbjct: 284 GNCITCEGRVDSQEYANIRSAMKVLMFTDTENWEISKLLAAILHLGNLQYEARTFENLDA 343 Query: 376 AEPDGTEVADKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTVEQVSNAVGALAKAVY 435 E + AA L +N DL+ L + E V+ + EQ + A K +Y Sbjct: 344 CEVLFSPSLATAASLLEVNPPDLMSCLTSRTLITRGETVSTPLSREQALDVRDAFVKGIY 403 Query: 436 EKMFLWMVARINQQL------DTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQ 489 ++F+W+V +IN + D K R+ IG+LDI GFE F NS EQLCINF NE LQ Sbjct: 404 GRLFVWIVDKINAAIYKPPSQDVKNSRR-SIGLLDIFGFENFAVNSFEQLCINFANEHLQ 462 Query: 490 QFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDT 549 QFF H+F LEQEEY E I+W I+F + A + KPM I S+++EE FPK TDT Sbjct: 463 QFFVRHVFKLEQEEYDLESIDWLHIEFTDNQDALDMIANKPMNIISLIDEESKFPKGTDT 522 Query: 550 SFKNKLYDQHLGKSANFQKPKVVKGKAEAHFALIHYAGVVDYNITGWLEKNKDPLNETVV 609 + +KL QH +AN+ P K E F + H+AG+V Y G+LEKN+D L+ ++ Sbjct: 523 TMLHKLNSQH-KLNANYIPP---KNNHETQFGINHFAGIVYYETQGFLEKNRDTLHGDII 578 Query: 610 GLYQKSAMKTLAQLFSGAQTAEGEGAGGGAKKGGKKKGSSFQTVSALFRENLNKLMTNLR 669 L S K + Q+F A A G +K+ T+S+ F+ +L LM L Sbjct: 579 QLVHSSRNKFIKQIFQ-ADVAMGAET--------RKRS---PTLSSQFKRSLELLMRTLG 626 Query: 670 STHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYK 729 + P FVRCI PNE K P + L + QLR +G++E IRI R G+P R + +F +RY+ Sbjct: 627 ACQPFFVRCIKPNEFKKPMLFDRHLCVRQLRYSGMMETIRIRRAGYPIRYSFVEFVERYR 686 Query: 730 VLNASAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDDKLAQ 789 VL P + D + +++ ++ H ++ G TK+F K LLE RD + Sbjct: 687 VLLPGVKPAYKQGDLRGTCQRMAEAVLGTHDDWQIGKTKIFLKDHHDMLLEVERDKAITD 746 Query: 790 LITRTQARCRGFLARVEYQRMVERREAIFCIQYNIRSFMNVKHWPWMKL-FFKIKPLLKS 848 + Q RGF R + ++ + A IQ + R K++ M+L F +++ L +S Sbjct: 747 RVILLQKVIRGFKDRSNFLKL---KNAATLIQRHWRGHNCRKNYGLMRLGFLRLQALHRS 803 Query: 849 AETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAE 908 + ++ ++ + + ++ RK ++ + L VQA A G+ Sbjct: 804 RKLHQQYRLARQRIIQFQAR-CRAYLVRKAFRHRLWAV--------LTVQAYARGM--IA 852 Query: 909 ERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKK------RKLEDECSELKKDIDD 962 R Q ++ + + +++ R +EE++ E++AKK RK ++ ++L ++ + Sbjct: 853 RRLHQRLRAEYLWRLEAEKM--RLAEEEKLRKEMSAKKAKEEAERKHQERLAQLAREDAE 910 Query: 963 LELTLAKVEKEKHATENKVKNLTEEM 988 EL KEK A K K L E+M Sbjct: 911 REL------KEKEAARRK-KELLEQM 929 >gi|189083798 myosin VIIA isoform 1 [Homo sapiens] Length = 2215 Score = 481 bits (1238), Expect = e-135 Identities = 326/926 (35%), Positives = 489/926 (52%), Gaps = 70/926 (7%) Query: 79 PMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYKPE 138 PM+P +EDM + L+E +L NL RY +IYTY+G V VNPY+ L +Y PE Sbjct: 58 PMHPTSVHGVEDMIRLGDLNEAGILRNLLIRYRDHLIYTYTGSILVAVNPYQLLSIYSPE 117 Query: 139 VVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFAT 198 + Y KK E PPHIF+I+DN Y M + +Q +I+GESGAGKT +TK ++Q+ A Sbjct: 118 HIRQYTNKKIGEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFLA- 176 Query: 199 IAVTGEKKKEEITSGKIQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTT 258 A++G+ +E Q++ A P+LEAFGNAKT+RNDNSSRFGK+I IHF Sbjct: 177 -AISGQ-----------HSWIEQQVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKR 224 Query: 259 GKLASADIETYLLEKSRVVFQLKAERSYHIFYQITSNKKPELIEMLLITTNPYDYPFVSQ 318 G + A IE YLLEKSRV Q ER+YH+FY + + + L + DY +++ Sbjct: 225 GAIEGAKIEQYLLEKSRVCRQALDERNYHVFYCMLEGMSEDQKKKLGL-GQASDYNYLAM 283 Query: 319 GE-ISVASIDDQEELMATDSAIDILGFTNEEKVSIYKLTGAVMHYGNLKFKQKQRE--EQ 375 G I+ D +E SA+ +L FT+ E I KL A++H GNL+++ + E + Sbjct: 284 GNCITCEGRVDSQEYANIRSAMKVLMFTDTENWEISKLLAAILHLGNLQYEARTFENLDA 343 Query: 376 AEPDGTEVADKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTVEQVSNAVGALAKAVY 435 E + AA L +N DL+ L + E V+ + EQ + A K +Y Sbjct: 344 CEVLFSPSLATAASLLEVNPPDLMSCLTSRTLITRGETVSTPLSREQALDVRDAFVKGIY 403 Query: 436 EKMFLWMVARINQQL------DTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQ 489 ++F+W+V +IN + D K R+ IG+LDI GFE F NS EQLCINF NE LQ Sbjct: 404 GRLFVWIVDKINAAIYKPPSQDVKNSRR-SIGLLDIFGFENFAVNSFEQLCINFANEHLQ 462 Query: 490 QFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDT 549 QFF H+F LEQEEY E I+W I+F + A + KPM I S+++EE FPK TDT Sbjct: 463 QFFVRHVFKLEQEEYDLESIDWLHIEFTDNQDALDMIANKPMNIISLIDEESKFPKGTDT 522 Query: 550 SFKNKLYDQHLGKSANFQKPKVVKGKAEAHFALIHYAGVVDYNITGWLEKNKDPLNETVV 609 + +KL QH +AN+ P K E F + H+AG+V Y G+LEKN+D L+ ++ Sbjct: 523 TMLHKLNSQH-KLNANYIPP---KNNHETQFGINHFAGIVYYETQGFLEKNRDTLHGDII 578 Query: 610 GLYQKSAMKTLAQLFSGAQTAEGEGAGGGAKKGGKKKGSSFQTVSALFRENLNKLMTNLR 669 L S K + Q+F A A G +K+ T+S+ F+ +L LM L Sbjct: 579 QLVHSSRNKFIKQIFQ-ADVAMGAET--------RKRS---PTLSSQFKRSLELLMRTLG 626 Query: 670 STHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYK 729 + P FVRCI PNE K P + L + QLR +G++E IRI R G+P R + +F +RY+ Sbjct: 627 ACQPFFVRCIKPNEFKKPMLFDRHLCVRQLRYSGMMETIRIRRAGYPIRYSFVEFVERYR 686 Query: 730 VLNASAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDDKLAQ 789 VL P + D + +++ ++ H ++ G TK+F K LLE RD + Sbjct: 687 VLLPGVKPAYKQGDLRGTCQRMAEAVLGTHDDWQIGKTKIFLKDHHDMLLEVERDKAITD 746 Query: 790 LITRTQARCRGFLARVEYQRMVERREAIFCIQYNIRSFMNVKHWPWMKL-FFKIKPLLKS 848 + Q RGF R + ++ + A IQ + R K++ M+L F +++ L +S Sbjct: 747 RVILLQKVIRGFKDRSNFLKL---KNAATLIQRHWRGHNCRKNYGLMRLGFLRLQALHRS 803 Query: 849 AETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAE 908 + ++ ++ + + ++ RK ++ + L VQA A G+ Sbjct: 804 RKLHQQYRLARQRIIQFQAR-CRAYLVRKAFRHRLWAV--------LTVQAYARGM--IA 852 Query: 909 ERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKK------RKLEDECSELKKDIDD 962 R Q ++ + + +++ R +EE++ E++AKK RK ++ ++L ++ + Sbjct: 853 RRLHQRLRAEYLWRLEAEKM--RLAEEEKLRKEMSAKKAKEEAERKHQERLAQLAREDAE 910 Query: 963 LELTLAKVEKEKHATENKVKNLTEEM 988 EL KEK A K K L E+M Sbjct: 911 REL------KEKEAARRK-KELLEQM 929 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.312 0.128 0.340 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 63,331,491 Number of Sequences: 37866 Number of extensions: 2892691 Number of successful extensions: 63617 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 840 Number of HSP's successfully gapped in prelim test: 1567 Number of HSP's that attempted gapping in prelim test: 13886 Number of HSP's gapped (non-prelim): 16284 length of query: 1941 length of database: 18,247,518 effective HSP length: 117 effective length of query: 1824 effective length of database: 13,817,196 effective search space: 25202565504 effective search space used: 25202565504 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.9 bits) S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.