Guide to the Human Genome
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Search of human proteins with 153792663

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|153792663 myosin, heavy chain 2, skeletal muscle, adult
[Homo sapiens]
         (1941 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo...  3751   0.0  
gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo...  3751   0.0  
gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo...  3588   0.0  
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [...  3513   0.0  
gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo ...  3498   0.0  
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H...  3231   0.0  
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo...  3146   0.0  
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s...  3137   0.0  
gi|156104908 myosin heavy chain 6 [Homo sapiens]                     3108   0.0  
gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta ...  2609   0.0  
gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens]             2318   0.0  
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho...  1423   0.0  
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho...  1423   0.0  
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho...  1423   0.0  
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho...  1423   0.0  
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]  1413   0.0  
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]   1410   0.0  
gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens]         1306   0.0  
gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens]         1305   0.0  
gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens]         1293   0.0  
gi|153945715 myosin VC [Homo sapiens]                                 608   e-173
gi|215982794 myosin VA isoform 2 [Homo sapiens]                       597   e-170
gi|215982791 myosin VA isoform 1 [Homo sapiens]                       594   e-169
gi|122937345 myosin VB [Homo sapiens]                                 564   e-160
gi|28416946 myosin 18A isoform a [Homo sapiens]                       509   e-143
gi|42794779 myosin 18A isoform b [Homo sapiens]                       506   e-143
gi|154354979 myosin X [Homo sapiens]                                  491   e-138
gi|189083802 myosin VIIA isoform 2 [Homo sapiens]                     481   e-135
gi|189083800 myosin VIIA isoform 3 [Homo sapiens]                     481   e-135
gi|189083798 myosin VIIA isoform 1 [Homo sapiens]                     481   e-135

>gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo
            sapiens]
          Length = 1941

 Score = 3751 bits (9726), Expect = 0.0
 Identities = 1941/1941 (100%), Positives = 1941/1941 (100%)

Query: 1    MSSDSELAVFGEAAPFLRKSERERIEAQNRPFDAKTSVFVAEPKESFVKGTIQSREGGKV 60
            MSSDSELAVFGEAAPFLRKSERERIEAQNRPFDAKTSVFVAEPKESFVKGTIQSREGGKV
Sbjct: 1    MSSDSELAVFGEAAPFLRKSERERIEAQNRPFDAKTSVFVAEPKESFVKGTIQSREGGKV 60

Query: 61   TVKTEGGATLTVKDDQVFPMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSG 120
            TVKTEGGATLTVKDDQVFPMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSG
Sbjct: 61   TVKTEGGATLTVKDDQVFPMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSG 120

Query: 121  LFCVTVNPYKWLPVYKPEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGE 180
            LFCVTVNPYKWLPVYKPEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGE
Sbjct: 121  LFCVTVNPYKWLPVYKPEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGE 180

Query: 181  SGAGKTVNTKRVIQYFATIAVTGEKKKEEITSGKIQGTLEDQIISANPLLEAFGNAKTVR 240
            SGAGKTVNTKRVIQYFATIAVTGEKKKEEITSGKIQGTLEDQIISANPLLEAFGNAKTVR
Sbjct: 181  SGAGKTVNTKRVIQYFATIAVTGEKKKEEITSGKIQGTLEDQIISANPLLEAFGNAKTVR 240

Query: 241  NDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVVFQLKAERSYHIFYQITSNKKPEL 300
            NDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVVFQLKAERSYHIFYQITSNKKPEL
Sbjct: 241  NDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVVFQLKAERSYHIFYQITSNKKPEL 300

Query: 301  IEMLLITTNPYDYPFVSQGEISVASIDDQEELMATDSAIDILGFTNEEKVSIYKLTGAVM 360
            IEMLLITTNPYDYPFVSQGEISVASIDDQEELMATDSAIDILGFTNEEKVSIYKLTGAVM
Sbjct: 301  IEMLLITTNPYDYPFVSQGEISVASIDDQEELMATDSAIDILGFTNEEKVSIYKLTGAVM 360

Query: 361  HYGNLKFKQKQREEQAEPDGTEVADKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTV 420
            HYGNLKFKQKQREEQAEPDGTEVADKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTV
Sbjct: 361  HYGNLKFKQKQREEQAEPDGTEVADKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTV 420

Query: 421  EQVSNAVGALAKAVYEKMFLWMVARINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLC 480
            EQVSNAVGALAKAVYEKMFLWMVARINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLC
Sbjct: 421  EQVSNAVGALAKAVYEKMFLWMVARINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLC 480

Query: 481  INFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEE 540
            INFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEE
Sbjct: 481  INFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEE 540

Query: 541  CMFPKATDTSFKNKLYDQHLGKSANFQKPKVVKGKAEAHFALIHYAGVVDYNITGWLEKN 600
            CMFPKATDTSFKNKLYDQHLGKSANFQKPKVVKGKAEAHFALIHYAGVVDYNITGWLEKN
Sbjct: 541  CMFPKATDTSFKNKLYDQHLGKSANFQKPKVVKGKAEAHFALIHYAGVVDYNITGWLEKN 600

Query: 601  KDPLNETVVGLYQKSAMKTLAQLFSGAQTAEGEGAGGGAKKGGKKKGSSFQTVSALFREN 660
            KDPLNETVVGLYQKSAMKTLAQLFSGAQTAEGEGAGGGAKKGGKKKGSSFQTVSALFREN
Sbjct: 601  KDPLNETVVGLYQKSAMKTLAQLFSGAQTAEGEGAGGGAKKGGKKKGSSFQTVSALFREN 660

Query: 661  LNKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRIL 720
            LNKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRIL
Sbjct: 661  LNKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRIL 720

Query: 721  YADFKQRYKVLNASAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLE 780
            YADFKQRYKVLNASAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLE
Sbjct: 721  YADFKQRYKVLNASAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLE 780

Query: 781  EMRDDKLAQLITRTQARCRGFLARVEYQRMVERREAIFCIQYNIRSFMNVKHWPWMKLFF 840
            EMRDDKLAQLITRTQARCRGFLARVEYQRMVERREAIFCIQYNIRSFMNVKHWPWMKLFF
Sbjct: 781  EMRDDKLAQLITRTQARCRGFLARVEYQRMVERREAIFCIQYNIRSFMNVKHWPWMKLFF 840

Query: 841  KIKPLLKSAETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAE 900
            KIKPLLKSAETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAE
Sbjct: 841  KIKPLLKSAETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAE 900

Query: 901  AEGLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDI 960
            AEGLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDI
Sbjct: 901  AEGLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDI 960

Query: 961  DDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEE 1020
            DDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEE
Sbjct: 961  DDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEE 1020

Query: 1021 DKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQ 1080
            DKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQ
Sbjct: 1021 DKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQ 1080

Query: 1081 QLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEK 1140
            QLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEK
Sbjct: 1081 QLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEK 1140

Query: 1141 QRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRK 1200
            QRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRK
Sbjct: 1141 QRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRK 1200

Query: 1201 KHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLED 1260
            KHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLED
Sbjct: 1201 KHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLED 1260

Query: 1261 QLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEE 1320
            QLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEE
Sbjct: 1261 QLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEE 1320

Query: 1321 LKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTK 1380
            LKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTK
Sbjct: 1321 LKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTK 1380

Query: 1381 YETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVER 1440
            YETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVER
Sbjct: 1381 YETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVER 1440

Query: 1441 TNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQ 1500
            TNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQ
Sbjct: 1441 TNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQ 1500

Query: 1501 LETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHE 1560
            LETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHE
Sbjct: 1501 LETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHE 1560

Query: 1561 EGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRL 1620
            EGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRL
Sbjct: 1561 EGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRL 1620

Query: 1621 KKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMV 1680
            KKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMV
Sbjct: 1621 KKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMV 1680

Query: 1681 ERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDI 1740
            ERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDI
Sbjct: 1681 ERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDI 1740

Query: 1741 SQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQ 1800
            SQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQ
Sbjct: 1741 SQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQ 1800

Query: 1801 LRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQT 1860
            LRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQT
Sbjct: 1801 LRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQT 1860

Query: 1861 EEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAE 1920
            EEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAE
Sbjct: 1861 EEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAE 1920

Query: 1921 SQVNKLRVKSREVHTKVISEE 1941
            SQVNKLRVKSREVHTKVISEE
Sbjct: 1921 SQVNKLRVKSREVHTKVISEE 1941


>gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo
            sapiens]
          Length = 1941

 Score = 3751 bits (9726), Expect = 0.0
 Identities = 1941/1941 (100%), Positives = 1941/1941 (100%)

Query: 1    MSSDSELAVFGEAAPFLRKSERERIEAQNRPFDAKTSVFVAEPKESFVKGTIQSREGGKV 60
            MSSDSELAVFGEAAPFLRKSERERIEAQNRPFDAKTSVFVAEPKESFVKGTIQSREGGKV
Sbjct: 1    MSSDSELAVFGEAAPFLRKSERERIEAQNRPFDAKTSVFVAEPKESFVKGTIQSREGGKV 60

Query: 61   TVKTEGGATLTVKDDQVFPMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSG 120
            TVKTEGGATLTVKDDQVFPMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSG
Sbjct: 61   TVKTEGGATLTVKDDQVFPMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSG 120

Query: 121  LFCVTVNPYKWLPVYKPEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGE 180
            LFCVTVNPYKWLPVYKPEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGE
Sbjct: 121  LFCVTVNPYKWLPVYKPEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGE 180

Query: 181  SGAGKTVNTKRVIQYFATIAVTGEKKKEEITSGKIQGTLEDQIISANPLLEAFGNAKTVR 240
            SGAGKTVNTKRVIQYFATIAVTGEKKKEEITSGKIQGTLEDQIISANPLLEAFGNAKTVR
Sbjct: 181  SGAGKTVNTKRVIQYFATIAVTGEKKKEEITSGKIQGTLEDQIISANPLLEAFGNAKTVR 240

Query: 241  NDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVVFQLKAERSYHIFYQITSNKKPEL 300
            NDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVVFQLKAERSYHIFYQITSNKKPEL
Sbjct: 241  NDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVVFQLKAERSYHIFYQITSNKKPEL 300

Query: 301  IEMLLITTNPYDYPFVSQGEISVASIDDQEELMATDSAIDILGFTNEEKVSIYKLTGAVM 360
            IEMLLITTNPYDYPFVSQGEISVASIDDQEELMATDSAIDILGFTNEEKVSIYKLTGAVM
Sbjct: 301  IEMLLITTNPYDYPFVSQGEISVASIDDQEELMATDSAIDILGFTNEEKVSIYKLTGAVM 360

Query: 361  HYGNLKFKQKQREEQAEPDGTEVADKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTV 420
            HYGNLKFKQKQREEQAEPDGTEVADKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTV
Sbjct: 361  HYGNLKFKQKQREEQAEPDGTEVADKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTV 420

Query: 421  EQVSNAVGALAKAVYEKMFLWMVARINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLC 480
            EQVSNAVGALAKAVYEKMFLWMVARINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLC
Sbjct: 421  EQVSNAVGALAKAVYEKMFLWMVARINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLC 480

Query: 481  INFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEE 540
            INFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEE
Sbjct: 481  INFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEE 540

Query: 541  CMFPKATDTSFKNKLYDQHLGKSANFQKPKVVKGKAEAHFALIHYAGVVDYNITGWLEKN 600
            CMFPKATDTSFKNKLYDQHLGKSANFQKPKVVKGKAEAHFALIHYAGVVDYNITGWLEKN
Sbjct: 541  CMFPKATDTSFKNKLYDQHLGKSANFQKPKVVKGKAEAHFALIHYAGVVDYNITGWLEKN 600

Query: 601  KDPLNETVVGLYQKSAMKTLAQLFSGAQTAEGEGAGGGAKKGGKKKGSSFQTVSALFREN 660
            KDPLNETVVGLYQKSAMKTLAQLFSGAQTAEGEGAGGGAKKGGKKKGSSFQTVSALFREN
Sbjct: 601  KDPLNETVVGLYQKSAMKTLAQLFSGAQTAEGEGAGGGAKKGGKKKGSSFQTVSALFREN 660

Query: 661  LNKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRIL 720
            LNKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRIL
Sbjct: 661  LNKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRIL 720

Query: 721  YADFKQRYKVLNASAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLE 780
            YADFKQRYKVLNASAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLE
Sbjct: 721  YADFKQRYKVLNASAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLE 780

Query: 781  EMRDDKLAQLITRTQARCRGFLARVEYQRMVERREAIFCIQYNIRSFMNVKHWPWMKLFF 840
            EMRDDKLAQLITRTQARCRGFLARVEYQRMVERREAIFCIQYNIRSFMNVKHWPWMKLFF
Sbjct: 781  EMRDDKLAQLITRTQARCRGFLARVEYQRMVERREAIFCIQYNIRSFMNVKHWPWMKLFF 840

Query: 841  KIKPLLKSAETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAE 900
            KIKPLLKSAETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAE
Sbjct: 841  KIKPLLKSAETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAE 900

Query: 901  AEGLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDI 960
            AEGLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDI
Sbjct: 901  AEGLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDI 960

Query: 961  DDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEE 1020
            DDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEE
Sbjct: 961  DDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEE 1020

Query: 1021 DKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQ 1080
            DKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQ
Sbjct: 1021 DKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQ 1080

Query: 1081 QLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEK 1140
            QLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEK
Sbjct: 1081 QLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEK 1140

Query: 1141 QRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRK 1200
            QRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRK
Sbjct: 1141 QRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRK 1200

Query: 1201 KHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLED 1260
            KHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLED
Sbjct: 1201 KHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLED 1260

Query: 1261 QLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEE 1320
            QLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEE
Sbjct: 1261 QLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEE 1320

Query: 1321 LKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTK 1380
            LKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTK
Sbjct: 1321 LKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTK 1380

Query: 1381 YETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVER 1440
            YETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVER
Sbjct: 1381 YETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVER 1440

Query: 1441 TNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQ 1500
            TNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQ
Sbjct: 1441 TNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQ 1500

Query: 1501 LETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHE 1560
            LETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHE
Sbjct: 1501 LETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHE 1560

Query: 1561 EGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRL 1620
            EGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRL
Sbjct: 1561 EGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRL 1620

Query: 1621 KKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMV 1680
            KKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMV
Sbjct: 1621 KKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMV 1680

Query: 1681 ERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDI 1740
            ERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDI
Sbjct: 1681 ERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDI 1740

Query: 1741 SQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQ 1800
            SQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQ
Sbjct: 1741 SQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQ 1800

Query: 1801 LRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQT 1860
            LRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQT
Sbjct: 1801 LRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQT 1860

Query: 1861 EEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAE 1920
            EEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAE
Sbjct: 1861 EEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAE 1920

Query: 1921 SQVNKLRVKSREVHTKVISEE 1941
            SQVNKLRVKSREVHTKVISEE
Sbjct: 1921 SQVNKLRVKSREVHTKVISEE 1941


>gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo
            sapiens]
          Length = 1939

 Score = 3588 bits (9305), Expect = 0.0
 Identities = 1839/1941 (94%), Positives = 1897/1941 (97%), Gaps = 2/1941 (0%)

Query: 1    MSSDSELAVFGEAAPFLRKSERERIEAQNRPFDAKTSVFVAEPKESFVKGTIQSREGGKV 60
            MSSDSE+A+FGEAAPFLRKSERERIEAQN+PFDAKTSVFV +PKESFVK T+QSREGGKV
Sbjct: 1    MSSDSEMAIFGEAAPFLRKSERERIEAQNKPFDAKTSVFVVDPKESFVKATVQSREGGKV 60

Query: 61   TVKTEGGATLTVKDDQVFPMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSG 120
            T KTE GAT+TVKDDQVFPMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSG
Sbjct: 61   TAKTEAGATVTVKDDQVFPMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSG 120

Query: 121  LFCVTVNPYKWLPVYKPEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGE 180
            LFCVTVNPYKWLPVY  EVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGE
Sbjct: 121  LFCVTVNPYKWLPVYNAEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGE 180

Query: 181  SGAGKTVNTKRVIQYFATIAVTGEKKKEEITSGKIQGTLEDQIISANPLLEAFGNAKTVR 240
            SGAGKTVNTKRVIQYFATIAVTGEKKKEE+TSGK+QGTLEDQIISANPLLEAFGNAKTVR
Sbjct: 181  SGAGKTVNTKRVIQYFATIAVTGEKKKEEVTSGKMQGTLEDQIISANPLLEAFGNAKTVR 240

Query: 241  NDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVVFQLKAERSYHIFYQITSNKKPEL 300
            NDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRV FQLKAERSYHIFYQI SNKKP+L
Sbjct: 241  NDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQIMSNKKPDL 300

Query: 301  IEMLLITTNPYDYPFVSQGEISVASIDDQEELMATDSAIDILGFTNEEKVSIYKLTGAVM 360
            IEMLLITTNPYDY FVSQGEI+V SIDDQEELMATDSAI+ILGFT++E+VSIYKLTGAVM
Sbjct: 301  IEMLLITTNPYDYAFVSQGEITVPSIDDQEELMATDSAIEILGFTSDERVSIYKLTGAVM 360

Query: 361  HYGNLKFKQKQREEQAEPDGTEVADKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTV 420
            HYGN+KFKQKQREEQAEPDGTEVADKAAYLQ+LNSADLLKALCYPRVKVGNEYVTKGQTV
Sbjct: 361  HYGNMKFKQKQREEQAEPDGTEVADKAAYLQNLNSADLLKALCYPRVKVGNEYVTKGQTV 420

Query: 421  EQVSNAVGALAKAVYEKMFLWMVARINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLC 480
            +QV NAVGALAKAVY+KMFLWMV RINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLC
Sbjct: 421  QQVYNAVGALAKAVYDKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLC 480

Query: 481  INFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEE 540
            INFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEE
Sbjct: 481  INFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEE 540

Query: 541  CMFPKATDTSFKNKLYDQHLGKSANFQKPKVVKGKAEAHFALIHYAGVVDYNITGWLEKN 600
            CMFPKATDTSFKNKLY+QHLGKS NFQKPK  KGK EAHF+LIHYAG VDYNI GWL+KN
Sbjct: 541  CMFPKATDTSFKNKLYEQHLGKSNNFQKPKPAKGKPEAHFSLIHYAGTVDYNIAGWLDKN 600

Query: 601  KDPLNETVVGLYQKSAMKTLAQLFSGAQTAEGEGAGGGAKKGGKKKGSSFQTVSALFREN 660
            KDPLNETVVGLYQKSAMKTLA LF GA  AE E  GG  KKGGKKKGSSFQTVSALFREN
Sbjct: 601  KDPLNETVVGLYQKSAMKTLALLFVGATGAEAEAGGG--KKGGKKKGSSFQTVSALFREN 658

Query: 661  LNKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRIL 720
            LNKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRIL
Sbjct: 659  LNKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRIL 718

Query: 721  YADFKQRYKVLNASAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLE 780
            YADFKQRYKVLNASAIPEGQFIDSKKASEKLL SIDIDHTQYKFGHTKVFFKAGLLGLLE
Sbjct: 719  YADFKQRYKVLNASAIPEGQFIDSKKASEKLLGSIDIDHTQYKFGHTKVFFKAGLLGLLE 778

Query: 781  EMRDDKLAQLITRTQARCRGFLARVEYQRMVERREAIFCIQYNIRSFMNVKHWPWMKLFF 840
            EMRD+KLAQLITRTQA CRGFLARVEYQ+MVERRE+IFCIQYN+R+FMNVKHWPWMKL+F
Sbjct: 779  EMRDEKLAQLITRTQAMCRGFLARVEYQKMVERRESIFCIQYNVRAFMNVKHWPWMKLYF 838

Query: 841  KIKPLLKSAETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAE 900
            KIKPLLKSAETEKEMA MKEEF+K K+ELAK+EAKRKELEEKMVTL++EKNDLQLQVQAE
Sbjct: 839  KIKPLLKSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAE 898

Query: 901  AEGLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDI 960
            A+ LADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDI
Sbjct: 899  ADSLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDI 958

Query: 961  DDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEE 1020
            DDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEE
Sbjct: 959  DDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEE 1018

Query: 1021 DKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQ 1080
            DKVNTLTKAKIKLEQQVDDLEGSLEQEKK+RMDLERAKRKLEGDLKLAQES MDIEN+KQ
Sbjct: 1019 DKVNTLTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDLKLAQESTMDIENDKQ 1078

Query: 1081 QLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEK 1140
            QLDEKLKKKEFE+S LQSKIEDEQALG+QLQKKIKELQARIEELEEEIEAERASRAKAEK
Sbjct: 1079 QLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERASRAKAEK 1138

Query: 1141 QRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRK 1200
            QRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRK
Sbjct: 1139 QRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRK 1198

Query: 1201 KHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLED 1260
            KHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASN+ETVSKAKGNLEKMCR LED
Sbjct: 1199 KHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALED 1258

Query: 1261 QLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEE 1320
            QLSE+K+KEEEQQRLINDLTAQR RLQTESGE+SRQLDEK+ LVSQLSRGKQAFTQQIEE
Sbjct: 1259 QLSEIKTKEEEQQRLINDLTAQRARLQTESGEYSRQLDEKDTLVSQLSRGKQAFTQQIEE 1318

Query: 1321 LKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTK 1380
            LKRQLEEEIKAK+ALAHALQSSRHDCDLLREQYEEEQE+KAELQRA+SKAN+EVAQWRTK
Sbjct: 1319 LKRQLEEEIKAKSALAHALQSSRHDCDLLREQYEEEQEAKAELQRAMSKANSEVAQWRTK 1378

Query: 1381 YETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVER 1440
            YETDAIQRTEELEEAKKKLAQRLQ AEEHVEAVNAKCASLEKTKQRLQNEVEDLM+DVER
Sbjct: 1379 YETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVER 1438

Query: 1441 TNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQ 1500
            TNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKE+RSL TELFKIKNAYEESLDQ
Sbjct: 1439 TNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKESRSLSTELFKIKNAYEESLDQ 1498

Query: 1501 LETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHE 1560
            LETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEK ELQAALEEAEASLEHE
Sbjct: 1499 LETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKSELQAALEEAEASLEHE 1558

Query: 1561 EGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRL 1620
            EGKILRIQLELNQVKSEVDRKIAEKDEEIDQ+KRNHIRIVESMQSTLDAEIRSRNDAIRL
Sbjct: 1559 EGKILRIQLELNQVKSEVDRKIAEKDEEIDQMKRNHIRIVESMQSTLDAEIRSRNDAIRL 1618

Query: 1621 KKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMV 1680
            KKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQ ILKDTQ+HLDDALRSQEDLKEQLAMV
Sbjct: 1619 KKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQAILKDTQLHLDDALRSQEDLKEQLAMV 1678

Query: 1681 ERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDI 1740
            ERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDI
Sbjct: 1679 ERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDI 1738

Query: 1741 SQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQ 1800
            SQ+QGEMEDI+QEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKN+EQTVKDLQ
Sbjct: 1739 SQIQGEMEDIIQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQ 1798

Query: 1801 LRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQT 1860
             RLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRN EAVKGLRKHER+VKELTYQT
Sbjct: 1799 HRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNVEAVKGLRKHERKVKELTYQT 1858

Query: 1861 EEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAE 1920
            EEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSN NL+KFR++QHELEEAEERADIAE
Sbjct: 1859 EEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNVNLSKFRRIQHELEEAEERADIAE 1918

Query: 1921 SQVNKLRVKSREVHTKVISEE 1941
            SQVNKLRVKSREVHTK+ISEE
Sbjct: 1919 SQVNKLRVKSREVHTKIISEE 1939


>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo
            sapiens]
          Length = 1937

 Score = 3513 bits (9110), Expect = 0.0
 Identities = 1796/1939 (92%), Positives = 1879/1939 (96%), Gaps = 5/1939 (0%)

Query: 2    SSDSELAVFGEAAPFLRKSERERIEAQNRPFDAKTSVFVAEPKESFVKGTIQSREGGKVT 61
            SSD+E+AVFGEAAP+LRKSE+ERIEAQN+PFDAKTSVFVAEPKES+VK TIQS+EGGKVT
Sbjct: 4    SSDAEMAVFGEAAPYLRKSEKERIEAQNKPFDAKTSVFVAEPKESYVKSTIQSKEGGKVT 63

Query: 62   VKTEGGATLTVKDDQVFPMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGL 121
            VKTEGGATLTV++DQVFPMNPPKYDKIEDMAMMTHLHEP VLYNLKERYAAWMIYTYSGL
Sbjct: 64   VKTEGGATLTVREDQVFPMNPPKYDKIEDMAMMTHLHEPGVLYNLKERYAAWMIYTYSGL 123

Query: 122  FCVTVNPYKWLPVYKPEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGES 181
            FCVTVNPYKWLPVYKPEVV AYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGES
Sbjct: 124  FCVTVNPYKWLPVYKPEVVAAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGES 183

Query: 182  GAGKTVNTKRVIQYFATIAVTGEKKKEEITSGKIQGTLEDQIISANPLLEAFGNAKTVRN 241
            GAGKTVNTKRVIQYFATIAVTGEKKK+E  SGK+QGTLEDQIISANPLLEAFGNAKTVRN
Sbjct: 184  GAGKTVNTKRVIQYFATIAVTGEKKKDE--SGKMQGTLEDQIISANPLLEAFGNAKTVRN 241

Query: 242  DNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVVFQLKAERSYHIFYQITSNKKPELI 301
            DNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRV FQLKAERSYHIFYQITSNKKP+LI
Sbjct: 242  DNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQITSNKKPDLI 301

Query: 302  EMLLITTNPYDYPFVSQGEISVASIDDQEELMATDSAIDILGFTNEEKVSIYKLTGAVMH 361
            EMLLITTNPYDY FVSQGEI+V SIDDQEELMATDSAIDILGFT EEKVSIYKLTGAVMH
Sbjct: 302  EMLLITTNPYDYAFVSQGEITVPSIDDQEELMATDSAIDILGFTPEEKVSIYKLTGAVMH 361

Query: 362  YGNLKFKQKQREEQAEPDGTEVADKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTVE 421
            YGN+KFKQKQREEQAEPDGTEVADKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTV+
Sbjct: 362  YGNMKFKQKQREEQAEPDGTEVADKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTVQ 421

Query: 422  QVSNAVGALAKAVYEKMFLWMVARINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCI 481
            QV NAVGALAKAVYEKMFLWMV RINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCI
Sbjct: 422  QVYNAVGALAKAVYEKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCI 481

Query: 482  NFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEEC 541
            NFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKP+GIFSILEEEC
Sbjct: 482  NFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPLGIFSILEEEC 541

Query: 542  MFPKATDTSFKNKLYDQHLGKSANFQKPKVVKGKAEAHFALIHYAGVVDYNITGWLEKNK 601
            MFPKATDTSFKNKLYDQHLGKSANFQKPKVVKGKAEAHF+LIHYAG VDYNITGWL+KNK
Sbjct: 542  MFPKATDTSFKNKLYDQHLGKSANFQKPKVVKGKAEAHFSLIHYAGTVDYNITGWLDKNK 601

Query: 602  DPLNETVVGLYQKSAMKTLAQLFSGAQTAEGEGAGGGAKKGGKKKGSSFQTVSALFRENL 661
            DPLN+TVVGLYQKSAMKTLA LFS   +AE + +   AKKG KKKGSSFQTVSALFRENL
Sbjct: 602  DPLNDTVVGLYQKSAMKTLASLFSTYASAEADSS---AKKGAKKKGSSFQTVSALFRENL 658

Query: 662  NKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILY 721
            NKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILY
Sbjct: 659  NKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILY 718

Query: 722  ADFKQRYKVLNASAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEE 781
             DFKQRYKVLNASAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEE
Sbjct: 719  GDFKQRYKVLNASAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEE 778

Query: 782  MRDDKLAQLITRTQARCRGFLARVEYQRMVERREAIFCIQYNIRSFMNVKHWPWMKLFFK 841
            MRD+KLAQ+ITRTQA CRGFL RVEYQ+M++RREA+FCIQYN+R+FMNVKHWPWMKLFFK
Sbjct: 779  MRDEKLAQIITRTQAVCRGFLMRVEYQKMLQRREALFCIQYNVRAFMNVKHWPWMKLFFK 838

Query: 842  IKPLLKSAETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEA 901
            IKPLLKSAETEKEMATMKEEFQK KDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQ+EA
Sbjct: 839  IKPLLKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEA 898

Query: 902  EGLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDID 961
            + LADAEERC+QLIK KIQLEAKIKEVTERAE+EEEINAELTAKKRKLEDECSELKKDID
Sbjct: 899  DSLADAEERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDID 958

Query: 962  DLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEED 1021
            DLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKL+KEKKALQE HQQTLDDLQAEED
Sbjct: 959  DLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEED 1018

Query: 1022 KVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQ 1081
            KVN LTKAK KLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQES MD+EN+KQQ
Sbjct: 1019 KVNILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQ 1078

Query: 1082 LDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQ 1141
            LDEKL+KKEFEISNL SKIEDEQA+ IQLQKKIKELQARIEEL EEIEAERASRAKAEKQ
Sbjct: 1079 LDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQ 1138

Query: 1142 RSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKK 1201
            RSDLSRELEEISERLEEAGGATSAQ+E+NKKREAEFQK+RRDLEEATLQHEA  A LRKK
Sbjct: 1139 RSDLSRELEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRKK 1198

Query: 1202 HADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQ 1261
            HADS+AELGEQIDNLQRVKQKLEKEKSE+KME DDL+SN E +SKAKGNLEKMCR+LEDQ
Sbjct: 1199 HADSMAELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGNLEKMCRSLEDQ 1258

Query: 1262 LSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEEL 1321
            +SELK+KEEEQQRLINDLTAQR RLQTE+GE+SRQLDEK+ALVSQLSR KQA TQQIEEL
Sbjct: 1259 VSELKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEEL 1318

Query: 1322 KRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKY 1381
            K QLEEE KAKNALAHALQSSRHDCDLLREQYEEEQE KAELQRALSKAN+EVAQWRTKY
Sbjct: 1319 KHQLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKY 1378

Query: 1382 ETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERT 1441
            ETDAIQRTEELEEAKKKLAQRLQ AEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVER+
Sbjct: 1379 ETDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERS 1438

Query: 1442 NAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQL 1501
            NAACAALDKKQRNFDK+L+EWKQK EET AELEASQKE+RSL TELFK+KN YEESLDQL
Sbjct: 1439 NAACAALDKKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELFKVKNVYEESLDQL 1498

Query: 1502 ETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEE 1561
            ETL+RENKNLQQEISDLTEQIAEGGK+IHELEKIKKQVEQEKCE+QAALEEAEASLEHEE
Sbjct: 1499 ETLRRENKNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEE 1558

Query: 1562 GKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLK 1621
            GKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNH R+VE+MQSTLDAEIRSRNDA+R+K
Sbjct: 1559 GKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHTRVVETMQSTLDAEIRSRNDALRVK 1618

Query: 1622 KKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVE 1681
            KKMEGDLNEMEIQLNHANR+AAE+LRNYRNTQGILK+TQ+HLDDALR QEDLKEQLA+VE
Sbjct: 1619 KKMEGDLNEMEIQLNHANRLAAESLRNYRNTQGILKETQLHLDDALRGQEDLKEQLAIVE 1678

Query: 1682 RRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDIS 1741
            RRANLLQAEIEEL ATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLE D+S
Sbjct: 1679 RRANLLQAEIEELWATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVS 1738

Query: 1742 QMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQL 1801
            Q+Q E+E+++QE+RNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKN+EQTVKDLQ 
Sbjct: 1739 QLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQH 1798

Query: 1802 RLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTE 1861
            RLDEAEQLALKGGKKQIQKLEARVRELEGEVE+EQKRNAEAVKGLRKHERRVKELTYQTE
Sbjct: 1799 RLDEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHERRVKELTYQTE 1858

Query: 1862 EDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAES 1921
            EDRKN+LRLQDLVDKLQAKVKSYKRQAEEAEEQSN NL+KFRKLQHELEEAEERADIAES
Sbjct: 1859 EDRKNVLRLQDLVDKLQAKVKSYKRQAEEAEEQSNANLSKFRKLQHELEEAEERADIAES 1918

Query: 1922 QVNKLRVKSREVHTKVISE 1940
            QVNKLRVKSREVHTK+ +E
Sbjct: 1919 QVNKLRVKSREVHTKISAE 1937


>gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo
            sapiens]
          Length = 1939

 Score = 3498 bits (9070), Expect = 0.0
 Identities = 1783/1941 (91%), Positives = 1870/1941 (96%), Gaps = 2/1941 (0%)

Query: 1    MSSDSELAVFGEAAPFLRKSERERIEAQNRPFDAKTSVFVAEPKESFVKGTIQSREGGKV 60
            MSSDSE+A+FGEAAPFLRKSE+ERIEAQN+PFDAKTSVFV +PKES+VK  +QSREGGKV
Sbjct: 1    MSSDSEMAIFGEAAPFLRKSEKERIEAQNKPFDAKTSVFVVDPKESYVKAIVQSREGGKV 60

Query: 61   TVKTEGGATLTVKDDQVFPMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSG 120
            T KTE GAT+TVK+DQVF MNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSG
Sbjct: 61   TAKTEAGATVTVKEDQVFSMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSG 120

Query: 121  LFCVTVNPYKWLPVYKPEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGE 180
            LFCVTVNPYKWLPVY PEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGE
Sbjct: 121  LFCVTVNPYKWLPVYNPEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGE 180

Query: 181  SGAGKTVNTKRVIQYFATIAVTGEKKKEEITSGKIQGTLEDQIISANPLLEAFGNAKTVR 240
            SGAGKTVNTKRVIQYFATIAVTGEKKKEE  SGK+QGTLEDQIISANPLLEAFGNAKTVR
Sbjct: 181  SGAGKTVNTKRVIQYFATIAVTGEKKKEEPASGKMQGTLEDQIISANPLLEAFGNAKTVR 240

Query: 241  NDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVVFQLKAERSYHIFYQITSNKKPEL 300
            NDNSSRFGKFIRIHFG TGKLASADIETYLLEKSRV FQLKAERSYHIFYQI SNKKPEL
Sbjct: 241  NDNSSRFGKFIRIHFGATGKLASADIETYLLEKSRVTFQLKAERSYHIFYQILSNKKPEL 300

Query: 301  IEMLLITTNPYDYPFVSQGEISVASIDDQEELMATDSAIDILGFTNEEKVSIYKLTGAVM 360
            IEMLLITTNPYD+ FVSQGEI+V SIDDQEELMATDSA+DILGFT +EKV+IYKLTGAVM
Sbjct: 301  IEMLLITTNPYDFAFVSQGEITVPSIDDQEELMATDSAVDILGFTADEKVAIYKLTGAVM 360

Query: 361  HYGNLKFKQKQREEQAEPDGTEVADKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTV 420
            HYGN+KFKQKQREEQAEPDGTEVADKAAYL SLNSADLLK+LCYPRVKVGNE+VTKGQTV
Sbjct: 361  HYGNMKFKQKQREEQAEPDGTEVADKAAYLTSLNSADLLKSLCYPRVKVGNEFVTKGQTV 420

Query: 421  EQVSNAVGALAKAVYEKMFLWMVARINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLC 480
            +QV NAVGALAKA+YEKMFLWMV RINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLC
Sbjct: 421  QQVYNAVGALAKAIYEKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLC 480

Query: 481  INFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEE 540
            INFTNEKLQQFFNHHMFVLEQEEYKKEGIEW FIDFGMDLAACIELIEKPMGIFSILEEE
Sbjct: 481  INFTNEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLAACIELIEKPMGIFSILEEE 540

Query: 541  CMFPKATDTSFKNKLYDQHLGKSANFQKPKVVKGKAEAHFALIHYAGVVDYNITGWLEKN 600
            CMFPKATDTSFKNKLY+QHLGKS NFQKPK  KGK EAHF+L+HYAG VDYNI GWL+KN
Sbjct: 541  CMFPKATDTSFKNKLYEQHLGKSNNFQKPKPAKGKPEAHFSLVHYAGTVDYNIAGWLDKN 600

Query: 601  KDPLNETVVGLYQKSAMKTLAQLFSGAQTAEGEGAGGGAKKGGKKKGSSFQTVSALFREN 660
            KDPLNETVVGLYQKSAMKTLA LFSGAQTAE EG GG  KKGGKKKGSSFQTVSALFREN
Sbjct: 601  KDPLNETVVGLYQKSAMKTLAFLFSGAQTAEAEGGGG--KKGGKKKGSSFQTVSALFREN 658

Query: 661  LNKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRIL 720
            LNKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRIL
Sbjct: 659  LNKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRIL 718

Query: 721  YADFKQRYKVLNASAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLE 780
            YADFKQRYKVLNASAIPEGQFIDSKKASEKLL SI+IDHTQYKFGHTKVFFKAGLLG LE
Sbjct: 719  YADFKQRYKVLNASAIPEGQFIDSKKASEKLLGSIEIDHTQYKFGHTKVFFKAGLLGTLE 778

Query: 781  EMRDDKLAQLITRTQARCRGFLARVEYQRMVERREAIFCIQYNIRSFMNVKHWPWMKLFF 840
            EMRD+KLAQLITRTQA CRGFL RVE+++M+ERRE+IFCIQYNIR+FMNVKHWPWMKL+F
Sbjct: 779  EMRDEKLAQLITRTQAICRGFLMRVEFRKMMERRESIFCIQYNIRAFMNVKHWPWMKLYF 838

Query: 841  KIKPLLKSAETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAE 900
            KIKPLLKSAETEKEMA MKEEF+K K+ELAK+EAKRKELEEKMVTL++EKNDLQLQVQAE
Sbjct: 839  KIKPLLKSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAE 898

Query: 901  AEGLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDI 960
            A+ LADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDI
Sbjct: 899  ADALADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDI 958

Query: 961  DDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEE 1020
            DDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQ EE
Sbjct: 959  DDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQMEE 1018

Query: 1021 DKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQ 1080
            DKVNTLTKAK KLEQQVDDLEGSLEQEKKL MDLERAKRKLEGDLKLAQES MD EN+KQ
Sbjct: 1019 DKVNTLTKAKTKLEQQVDDLEGSLEQEKKLCMDLERAKRKLEGDLKLAQESTMDTENDKQ 1078

Query: 1081 QLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEK 1140
            QL+EKLKKKEFE+SNLQ KIEDEQAL IQLQKKIKELQARIEELEEEIEAERASRAKAEK
Sbjct: 1079 QLNEKLKKKEFEMSNLQGKIEDEQALAIQLQKKIKELQARIEELEEEIEAERASRAKAEK 1138

Query: 1141 QRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRK 1200
            QRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEE+TLQHEATAA LRK
Sbjct: 1139 QRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEESTLQHEATAAALRK 1198

Query: 1201 KHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLED 1260
            KHADSVAELGEQID+LQRVKQKLEKEKSE+KMEI+DLASN+ETVSKAK N EKMCRTLED
Sbjct: 1199 KHADSVAELGEQIDSLQRVKQKLEKEKSELKMEINDLASNMETVSKAKANFEKMCRTLED 1258

Query: 1261 QLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEE 1320
            QLSE+K+KEEEQQRLIN+L+AQ+ RL TESGEFSRQLDEK+A+VSQLSRGKQAFTQQIEE
Sbjct: 1259 QLSEIKTKEEEQQRLINELSAQKARLHTESGEFSRQLDEKDAMVSQLSRGKQAFTQQIEE 1318

Query: 1321 LKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTK 1380
            LKRQLEEE KAK+ LAHALQS+RHDCDLLREQYEEEQE+KAELQR +SKAN+EVAQWRTK
Sbjct: 1319 LKRQLEEETKAKSTLAHALQSARHDCDLLREQYEEEQEAKAELQRGMSKANSEVAQWRTK 1378

Query: 1381 YETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVER 1440
            YETDAIQRTEELEEAKKKLAQRLQ AEEHVEAVN+KCASLEKTKQRLQNEVEDLM+DVER
Sbjct: 1379 YETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNSKCASLEKTKQRLQNEVEDLMIDVER 1438

Query: 1441 TNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQ 1500
            +NAAC ALDKKQRNFDK+LAEWKQK EET AELEASQKE+RSL TELFK+KNAYEESLD 
Sbjct: 1439 SNAACIALDKKQRNFDKVLAEWKQKYEETQAELEASQKESRSLSTELFKVKNAYEESLDH 1498

Query: 1501 LETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHE 1560
            LETLKRENKNLQQEISDLTEQIAEGGK IHELEK+KKQ++ EK ELQ +LEEAEASLEHE
Sbjct: 1499 LETLKRENKNLQQEISDLTEQIAEGGKHIHELEKVKKQLDHEKSELQTSLEEAEASLEHE 1558

Query: 1561 EGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRL 1620
            EGKILRIQLELNQVKSE+DRKIAEKDEE+DQLKRNH+R+VESMQSTLDAEIRSRNDA+R+
Sbjct: 1559 EGKILRIQLELNQVKSEIDRKIAEKDEELDQLKRNHLRVVESMQSTLDAEIRSRNDALRI 1618

Query: 1621 KKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMV 1680
            KKKMEGDLNEMEIQLNHANR AAEALRN RNTQGILKDTQ+HLDDA+R Q+DLKEQLAMV
Sbjct: 1619 KKKMEGDLNEMEIQLNHANRQAAEALRNLRNTQGILKDTQLHLDDAIRGQDDLKEQLAMV 1678

Query: 1681 ERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDI 1740
            ERRANL+QAE+EELRA+LE+TER RK+AEQELLDASERVQLLHTQNTSLINTKKKLETDI
Sbjct: 1679 ERRANLMQAEVEELRASLERTERGRKMAEQELLDASERVQLLHTQNTSLINTKKKLETDI 1738

Query: 1741 SQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQ 1800
            SQ+QGEMEDI+QEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQ
Sbjct: 1739 SQIQGEMEDIVQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQ 1798

Query: 1801 LRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQT 1860
            LRLDEAEQLALKGGKKQIQKLEARVRELE EVESEQK N EAVKGLRKHERRVKELTYQT
Sbjct: 1799 LRLDEAEQLALKGGKKQIQKLEARVRELESEVESEQKHNVEAVKGLRKHERRVKELTYQT 1858

Query: 1861 EEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAE 1920
            EEDRKNILRLQDLVDKLQ KVK+YKRQAEEAEEQSN NLAKFRKLQHELEEA+ERADIAE
Sbjct: 1859 EEDRKNILRLQDLVDKLQTKVKAYKRQAEEAEEQSNVNLAKFRKLQHELEEAKERADIAE 1918

Query: 1921 SQVNKLRVKSREVHTKVISEE 1941
            SQVNKLRVKSREVHTKVISEE
Sbjct: 1919 SQVNKLRVKSREVHTKVISEE 1939


>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
            sapiens]
          Length = 1940

 Score = 3231 bits (8378), Expect = 0.0
 Identities = 1639/1932 (84%), Positives = 1788/1932 (92%), Gaps = 5/1932 (0%)

Query: 1    MSSDSELAVFGEAAPFLRKSERERIEAQNRPFDAKTSVFVAEPKESFVKGTIQSREGGKV 60
            MSSD+E+ VFG AAPFLRKSE+ERIEAQN+PFDAKT  FV + KE + KG I+S + GKV
Sbjct: 1    MSSDTEMEVFGIAAPFLRKSEKERIEAQNQPFDAKTYCFVVDSKEEYAKGKIKSSQDGKV 60

Query: 61   TVKTEGGATLTVKDDQVFPMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSG 120
            TV+TE   TL VK + V+ MNPPK+D+IEDMAM+THL+EPAVLYNLK+RY +WMIYTYSG
Sbjct: 61   TVETEDNRTLVVKPEDVYAMNPPKFDRIEDMAMLTHLNEPAVLYNLKDRYTSWMIYTYSG 120

Query: 121  LFCVTVNPYKWLPVYKPEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGE 180
            LFCVTVNPYKWLPVY PEVV  YRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGE
Sbjct: 121  LFCVTVNPYKWLPVYNPEVVEGYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGE 180

Query: 181  SGAGKTVNTKRVIQYFATIAVTGEKKKEEITSGKIQGTLEDQIISANPLLEAFGNAKTVR 240
            SGAGKTVNTKRVIQYFATIA TG+  K++    K++GTLEDQIISANPLLEAFGNAKTVR
Sbjct: 181  SGAGKTVNTKRVIQYFATIAATGDLAKKK--DSKMKGTLEDQIISANPLLEAFGNAKTVR 238

Query: 241  NDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVVFQLKAERSYHIFYQITSNKKPEL 300
            NDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRV FQLKAERSYHIFYQI SNKKPEL
Sbjct: 239  NDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQILSNKKPEL 298

Query: 301  IEMLLITTNPYDYPFVSQGEISVASIDDQEELMATDSAIDILGFTNEEKVSIYKLTGAVM 360
            IE+LLITTNPYDYPF+SQGEI VASIDD EEL+ATDSAIDILGFT EEK  +YKLTGAVM
Sbjct: 299  IELLLITTNPYDYPFISQGEILVASIDDAEELLATDSAIDILGFTPEEKSGLYKLTGAVM 358

Query: 361  HYGNLKFKQKQREEQAEPDGTEVADKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTV 420
            HYGN+KFKQKQREEQAEPDGTEVADK AYL  LNS+DLLKALC+PRVKVGNEYVTKGQTV
Sbjct: 359  HYGNMKFKQKQREEQAEPDGTEVADKTAYLMGLNSSDLLKALCFPRVKVGNEYVTKGQTV 418

Query: 421  EQVSNAVGALAKAVYEKMFLWMVARINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLC 480
            +QV +AV AL+K+VYEK+FLWMV RINQQLDTK PRQ+FIGVLDIAGFEIF++NSLEQLC
Sbjct: 419  DQVHHAVNALSKSVYEKLFLWMVTRINQQLDTKLPRQHFIGVLDIAGFEIFEYNSLEQLC 478

Query: 481  INFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEE 540
            INFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEE
Sbjct: 479  INFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEE 538

Query: 541  CMFPKATDTSFKNKLYDQHLGKSANFQKPKVVKGKAEAHFALIHYAGVVDYNITGWLEKN 600
            CMFPKATDTSFKNKLYDQHLGKS NFQKPKVVKG+AEAHF+LIHYAG VDY+++GWLEKN
Sbjct: 539  CMFPKATDTSFKNKLYDQHLGKSNNFQKPKVVKGRAEAHFSLIHYAGTVDYSVSGWLEKN 598

Query: 601  KDPLNETVVGLYQKSAMKTLAQLFSGAQTAEGEGAGGGAKKGGKKKGSSFQTVSALFREN 660
            KDPLNETVVGLYQKS+ + LA L++   TA+   A  G KK  KKKGSSFQTVSALFREN
Sbjct: 599  KDPLNETVVGLYQKSSNRLLAHLYATFATAD---ADSGKKKVAKKKGSSFQTVSALFREN 655

Query: 661  LNKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRIL 720
            LNKLM+NLR+THPHFVRCIIPNETKTPGAMEH LVLHQLRCNGVLEGIRICRKGFP+RIL
Sbjct: 656  LNKLMSNLRTTHPHFVRCIIPNETKTPGAMEHSLVLHQLRCNGVLEGIRICRKGFPNRIL 715

Query: 721  YADFKQRYKVLNASAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLE 780
            Y DFKQRY+VLNASAIPEGQFIDSKKA EKLLASIDIDHTQYKFGHTKVFFKAGLLG LE
Sbjct: 716  YGDFKQRYRVLNASAIPEGQFIDSKKACEKLLASIDIDHTQYKFGHTKVFFKAGLLGTLE 775

Query: 781  EMRDDKLAQLITRTQARCRGFLARVEYQRMVERREAIFCIQYNIRSFMNVKHWPWMKLFF 840
            EMRDD+LA+LITRTQA CRGFL RVE+Q+MV+RRE+IFCIQYNIRSFMNVKHWPWMKLFF
Sbjct: 776  EMRDDRLAKLITRTQAVCRGFLMRVEFQKMVQRRESIFCIQYNIRSFMNVKHWPWMKLFF 835

Query: 841  KIKPLLKSAETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAE 900
            KIKPLLKSAETEKEMATMKEEFQK KDELAKSEAKRKELEEK+VTL++EKNDLQLQVQAE
Sbjct: 836  KIKPLLKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAE 895

Query: 901  AEGLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDI 960
            +E L DAEERCDQLIK K QLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDI
Sbjct: 896  SENLLDAEERCDQLIKAKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDI 955

Query: 961  DDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEE 1020
            DDLELTLAKVEKEKHATENKVKNLTEE++GLDETIAKLT+EKKALQEAHQQ LDDLQAEE
Sbjct: 956  DDLELTLAKVEKEKHATENKVKNLTEELSGLDETIAKLTREKKALQEAHQQALDDLQAEE 1015

Query: 1021 DKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQ 1080
            DKVN+L K K KLEQQV+DLE SLEQEKKLR+DLER KRKLEGDLKLAQESI+D+EN+KQ
Sbjct: 1016 DKVNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQ 1075

Query: 1081 QLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEK 1140
            QLDE+LKKK+FE   LQSK+EDEQ LG+Q QKKIKELQARIEELEEEIEAERA+RAK EK
Sbjct: 1076 QLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEK 1135

Query: 1141 QRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRK 1200
            QRSD +RELEE+SERLEEAGG TS QIE+NKKREAEF K+RRDLEEATLQHEA  A LRK
Sbjct: 1136 QRSDYARELEELSERLEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEAMVAALRK 1195

Query: 1201 KHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLED 1260
            KHADSVAELGEQIDNLQRVKQKLEKEKSE K+EIDDL+S++E+VSK+K NLEK+CRTLED
Sbjct: 1196 KHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLED 1255

Query: 1261 QLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEE 1320
            QLSE + K EE QR +++LT Q+ RLQTE+GE SRQL+EKE++VSQLSR KQAFTQQ EE
Sbjct: 1256 QLSEARGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEE 1315

Query: 1321 LKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTK 1380
            LKRQLEEE KAKNALAHALQSSRHDCDLLREQYEEEQE KAELQRALSKAN+EVAQWRTK
Sbjct: 1316 LKRQLEEENKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTK 1375

Query: 1381 YETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVER 1440
            YETDAIQRTEELEEAKKKLAQRLQ +EE VEAVNAKCASLEKTKQRLQ EVEDLM+DVER
Sbjct: 1376 YETDAIQRTEELEEAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVER 1435

Query: 1441 TNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQ 1500
             N+  AALDKKQRNFDK+LAEWK KCEE+ AELEAS KE+RSL TELFK+KNAYEE+LDQ
Sbjct: 1436 ANSLAAALDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQ 1495

Query: 1501 LETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHE 1560
            LET+KRENKNL+QEI+DLTEQIAE GK IHELEK +KQ+E EK ++Q ALEEAEA+LEHE
Sbjct: 1496 LETVKRENKNLEQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQLALEEAEAALEHE 1555

Query: 1561 EGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRL 1620
            E KILRIQLEL QVKSE+DRKIAEKDEEI+QLKRN+ R VE+MQS LDAE+RSRN+AIRL
Sbjct: 1556 EAKILRIQLELTQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSALDAEVRSRNEAIRL 1615

Query: 1621 KKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMV 1680
            KKKMEGDLNE+EIQL+HANR AAE L++ R+ QG LKDTQ+HLDDALR QEDLKEQLA+V
Sbjct: 1616 KKKMEGDLNEIEIQLSHANRQAAETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIV 1675

Query: 1681 ERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDI 1740
            ERRANLLQAE+EELRATLEQTER+RK+AEQELLD++ERVQLLHTQNTSLI+TKKKLETD+
Sbjct: 1676 ERRANLLQAEVEELRATLEQTERARKLAEQELLDSNERVQLLHTQNTSLIHTKKKLETDL 1735

Query: 1741 SQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQ 1800
             Q+Q E+ED  ++ARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKN+EQTVKDLQ
Sbjct: 1736 MQLQSEVEDASRDARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQ 1795

Query: 1801 LRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQT 1860
             RLDEAEQLALKGGKKQIQKLE R+RELE E+E EQK+N E+VKGLRK+ERRVKELTYQ+
Sbjct: 1796 HRLDEAEQLALKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLRKYERRVKELTYQS 1855

Query: 1861 EEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAE 1920
            EEDRKN+LRLQDLVDKLQ KVKSYKRQAEEA+EQ+N +L KFRK QHELEEAEERADIAE
Sbjct: 1856 EEDRKNVLRLQDLVDKLQVKVKSYKRQAEEADEQANAHLTKFRKAQHELEEAEERADIAE 1915

Query: 1921 SQVNKLRVKSRE 1932
            SQVNKLR K+R+
Sbjct: 1916 SQVNKLRAKTRD 1927



 Score =  224 bits (571), Expect = 6e-58
 Identities = 241/988 (24%), Positives = 448/988 (45%), Gaps = 150/988 (15%)

Query: 996  AKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLE 1055
            A+  KE   ++E  Q+T D+L   E K   L +  + L Q+ +DL+  ++ E        
Sbjct: 844  AETEKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAES------- 896

Query: 1056 RAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIK 1115
                          E+++D E   ++ D+ +K K                   QL+ KIK
Sbjct: 897  --------------ENLLDAE---ERCDQLIKAK------------------FQLEAKIK 921

Query: 1116 ELQARIEELEEEIEAE-RASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKRE 1174
            E+  R E+ EEEI AE  A + K E + S+L ++++++          T A++E  K++ 
Sbjct: 922  EVTERAED-EEEINAELTAKKRKLEDECSELKKDIDDLE--------LTLAKVE--KEKH 970

Query: 1175 AEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQK---LEKEKSEMK 1231
            A   K++   EE +   E  A   R+K A   A   + +D+LQ  + K   L K KS+++
Sbjct: 971  ATENKVKNLTEELSGLDETIAKLTREKKALQEAHQ-QALDDLQAEEDKVNSLNKTKSKLE 1029

Query: 1232 MEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESG 1291
             +++DL S++E   K + +LE+  R LE    +LK  +E    L ND      RL+ +  
Sbjct: 1030 QQVEDLESSLEQEKKLRVDLERNKRKLE---GDLKLAQESILDLENDKQQLDERLKKKDF 1086

Query: 1292 EFSR---QLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDL 1348
            E+ +   ++++++ L  Q  +  +    +IEEL    EEEI+A+ A     +  R D   
Sbjct: 1087 EYCQLQSKVEDEQTLGLQFQKKIKELQARIEEL----EEEIEAERATRAKTEKQRSD--- 1139

Query: 1349 LREQYEEEQESKAE-LQRALSKANTEVAQWRTKYETDAIQRTEELEEA-----------K 1396
                Y  E E  +E L+ A    +T++ +   K E + ++   +LEEA           +
Sbjct: 1140 ----YARELEELSERLEEAGGVTSTQI-ELNKKREAEFLKLRRDLEEATLQHEAMVAALR 1194

Query: 1397 KKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFD 1456
            KK A  +    E ++ +      LEK K   + E++DL   +E  + + A L+K  R  +
Sbjct: 1195 KKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLE 1254

Query: 1457 KILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEIS 1516
              L+E + K EE    L     +   L TE  ++    EE    +  L R  +   Q+  
Sbjct: 1255 DQLSEARGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTE 1314

Query: 1517 DLTEQIAEGGKRI-----------HELEKIKKQVEQE---KCELQAALEEAEASLEHEEG 1562
            +L  Q+ E  K             H+ + +++Q E+E   K ELQ AL +A +       
Sbjct: 1315 ELKRQLEEENKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANS------- 1367

Query: 1563 KILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKK 1622
                   E+ Q +++ +    ++ EE+++ K+   + ++  +  ++A         + K+
Sbjct: 1368 -------EVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQ 1420

Query: 1623 KMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQE-DLKEQLAMVE 1681
            +++G++ ++ + +  AN +AA   +  RN   +L + +   +++    E  LKE  ++  
Sbjct: 1421 RLQGEVEDLMVDVERANSLAAALDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLST 1480

Query: 1682 RRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDIS 1741
                L  A  EE    LE  +R  K  EQE+ D +E++     +N   I+  +K    I 
Sbjct: 1481 ELFKLKNA-YEEALDQLETVKRENKNLEQEIADLTEQI----AENGKTIHELEKSRKQIE 1535

Query: 1742 QMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSA-----HLERMKKNMEQTV 1796
              + +++  L+EA  A E  +  I    +   ++K E D         +E++K+N ++TV
Sbjct: 1536 LEKADIQLALEEAEAALEHEEAKILRIQLELTQVKSEIDRKIAEKDEEIEQLKRNYQRTV 1595

Query: 1797 KDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKEL 1856
            + +Q  LD AE  +     +  +K+E  + E+E ++    ++ AE +K LR  + ++K+ 
Sbjct: 1596 ETMQSALD-AEVRSRNEAIRLKKKMEGDLNEIEIQLSHANRQAAETLKHLRSVQGQLKDT 1654

Query: 1857 ------TYQTEEDRKNILRL-QDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKL-QHE 1908
                    + +ED K  L + +   + LQA+V+  +   E+ E        + RKL + E
Sbjct: 1655 QLHLDDALRGQEDLKEQLAIVERRANLLQAEVEELRATLEQTE--------RARKLAEQE 1706

Query: 1909 LEEAEERADIAESQVNKLRVKSREVHTK 1936
            L ++ ER  +  +Q   L      +HTK
Sbjct: 1707 LLDSNERVQLLHTQNTSL------IHTK 1728



 Score = 82.0 bits (201), Expect = 5e-15
 Identities = 79/341 (23%), Positives = 155/341 (45%), Gaps = 38/341 (11%)

Query: 847  KSAETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLAD 906
            ++AET K + +++ + +  +  L  +   +++L+E++  + +  N LQ +V+ E     +
Sbjct: 1636 QAAETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEVE-ELRATLE 1694

Query: 907  AEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELT 966
              ER  +L       E ++ +  ER +     N  L   K+KLE +  +L+ +++D    
Sbjct: 1695 QTERARKLA------EQELLDSNERVQLLHTQNTSLIHTKKKLETDLMQLQSEVEDASRD 1748

Query: 967  LAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTL 1026
                E++          + EE+    +T A L + KK L+    QT+ DLQ   D+   L
Sbjct: 1749 ARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLE----QTVKDLQHRLDEAEQL 1804

Query: 1027 TKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKL 1086
                         L+G  +Q +KL   +   + +LEG+ K   ES+  +   ++++ E  
Sbjct: 1805 A------------LKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLRKYERRVKELT 1852

Query: 1087 KKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLS 1146
             + E +  N+  +++D   L  +LQ K+K  + + EE +E+  A      KA+       
Sbjct: 1853 YQSEEDRKNV-LRLQD---LVDKLQVKVKSYKRQAEEADEQANAHLTKFRKAQ------- 1901

Query: 1147 RELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEA 1187
             ELEE  ER + A     +Q+   + +  +F   R  + E+
Sbjct: 1902 HELEEAEERADIA----ESQVNKLRAKTRDFTSSRMVVHES 1938



 Score = 42.7 bits (99), Expect = 0.003
 Identities = 29/130 (22%), Positives = 61/130 (46%), Gaps = 7/130 (5%)

Query: 1815 KKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLV 1874
            +K++  ++   ++ + E+   + +  E  + L    +   +L  Q + + +N+L  ++  
Sbjct: 847  EKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDAEERC 906

Query: 1875 DKL-------QAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAESQVNKLR 1927
            D+L       +AK+K    +AE+ EE +    AK RKL+ E  E ++  D  E  + K+ 
Sbjct: 907  DQLIKAKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVE 966

Query: 1928 VKSREVHTKV 1937
             +      KV
Sbjct: 967  KEKHATENKV 976


>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
            sapiens]
          Length = 1938

 Score = 3146 bits (8157), Expect = 0.0
 Identities = 1583/1940 (81%), Positives = 1766/1940 (91%), Gaps = 2/1940 (0%)

Query: 1    MSSDSELAVFGEAAPFLRKSERERIEAQNRPFDAKTSVFVAEPKESFVKGTIQSREGGKV 60
            MSSD+E+A+FGEAAP+LRK E+ERIEAQNRPFD+K + FVA+ KE +VKG IQ+RE  KV
Sbjct: 1    MSSDAEMAIFGEAAPYLRKPEKERIEAQNRPFDSKKACFVADNKEMYVKGMIQTRENDKV 60

Query: 61   TVKTEGGATLTVKDDQVFPMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSG 120
             VKT     LT+ +DQVFPMNPPK+DKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSG
Sbjct: 61   IVKTLDDRMLTLNNDQVFPMNPPKFDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSG 120

Query: 121  LFCVTVNPYKWLPVYKPEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGE 180
            LFCVTVNPYKWLPVYKPEVV AYRGKKRQEAPPHIFSISDNAYQFMLTDR+NQSILITGE
Sbjct: 121  LFCVTVNPYKWLPVYKPEVVAAYRGKKRQEAPPHIFSISDNAYQFMLTDRDNQSILITGE 180

Query: 181  SGAGKTVNTKRVIQYFATIAVTGEKKKEEITSGKIQGTLEDQIISANPLLEAFGNAKTVR 240
            SGAGKTVNTKRVIQYFATIAVTG+KKKE    GK+QGTLEDQII ANPLLEAFGNAKTVR
Sbjct: 181  SGAGKTVNTKRVIQYFATIAVTGDKKKET-QPGKMQGTLEDQIIQANPLLEAFGNAKTVR 239

Query: 241  NDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVVFQLKAERSYHIFYQITSNKKPEL 300
            NDNSSRFGKFIRIHFG TGKLASADIETYLLEKSRV FQL +ERSYHIFYQI SNKKPEL
Sbjct: 240  NDNSSRFGKFIRIHFGATGKLASADIETYLLEKSRVTFQLSSERSYHIFYQIMSNKKPEL 299

Query: 301  IEMLLITTNPYDYPFVSQGEISVASIDDQEELMATDSAIDILGFTNEEKVSIYKLTGAVM 360
            I++LLI+TNP+D+PFVSQGE++VASIDD EEL+ATD+AIDILGF++EEKV IYKLTGAVM
Sbjct: 300  IDLLLISTNPFDFPFVSQGEVTVASIDDSEELLATDNAIDILGFSSEEKVGIYKLTGAVM 359

Query: 361  HYGNLKFKQKQREEQAEPDGTEVADKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTV 420
            HYGN+KFKQKQREEQAEPDGTEVADKA YL  LNSA++LK LC PRVKVGNEYVTKGQ V
Sbjct: 360  HYGNMKFKQKQREEQAEPDGTEVADKAGYLMGLNSAEMLKGLCCPRVKVGNEYVTKGQNV 419

Query: 421  EQVSNAVGALAKAVYEKMFLWMVARINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLC 480
            +QV+N+VGALAKAVYEKMFLWMV RINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLC
Sbjct: 420  QQVTNSVGALAKAVYEKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLC 479

Query: 481  INFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEE 540
            INFTNEKLQQFFNHHMFVLEQEEYKKEGIEW FIDFGMDLAACIELIEKPMGIFSILEEE
Sbjct: 480  INFTNEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLAACIELIEKPMGIFSILEEE 539

Query: 541  CMFPKATDTSFKNKLYDQHLGKSANFQKPKVVKGKAEAHFALIHYAGVVDYNITGWLEKN 600
            CMFPKATDTSFKNKLYDQHLGKS NFQKPK  KGKAEAHF+L+HYAG VDYNI GWL+KN
Sbjct: 540  CMFPKATDTSFKNKLYDQHLGKSNNFQKPKPAKGKAEAHFSLVHYAGTVDYNIAGWLDKN 599

Query: 601  KDPLNETVVGLYQKSAMKTLAQLFSGAQTAEGEGAGGGAKKGGKKKGSSFQTVSALFREN 660
            KDPLNETVVGLYQKS++K L+ LFS    AE  G  GG+KKGGKKKGSSFQTVSA+FREN
Sbjct: 600  KDPLNETVVGLYQKSSLKLLSFLFSNYAGAE-TGDSGGSKKGGKKKGSSFQTVSAVFREN 658

Query: 661  LNKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRIL 720
            LNKLMTNLRSTHPHFVRC+IPNETKTPG M+H LV+HQLRCNGVLEGIRICRKGFPSRIL
Sbjct: 659  LNKLMTNLRSTHPHFVRCLIPNETKTPGVMDHYLVMHQLRCNGVLEGIRICRKGFPSRIL 718

Query: 721  YADFKQRYKVLNASAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLE 780
            YADFKQRY++LNASAIPEGQFIDSK ASEKLL SID+D  Q++FG+TKVFFKAGLLGLLE
Sbjct: 719  YADFKQRYRILNASAIPEGQFIDSKNASEKLLNSIDVDREQFRFGNTKVFFKAGLLGLLE 778

Query: 781  EMRDDKLAQLITRTQARCRGFLARVEYQRMVERREAIFCIQYNIRSFMNVKHWPWMKLFF 840
            EMRD+KL  L+T TQA CRG+L RVE+++M+ERR++IFCIQYNIRSFMNVKHWPWM LFF
Sbjct: 779  EMRDEKLVTLMTSTQAVCRGYLMRVEFKKMMERRDSIFCIQYNIRSFMNVKHWPWMNLFF 838

Query: 841  KIKPLLKSAETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAE 900
            KIKPLLKSAE EKEMATMKE+F++ K+ELA+SEA+RKELEEKMV+LL+EKNDLQLQVQ+E
Sbjct: 839  KIKPLLKSAEAEKEMATMKEDFERTKEELARSEARRKELEEKMVSLLQEKNDLQLQVQSE 898

Query: 901  AEGLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDI 960
             E L DAEERC+ LIK+KI LEAK+KE+TER E+EEE+N+EL AKKR LED+CS LK+DI
Sbjct: 899  TENLMDAEERCEGLIKSKILLEAKVKELTERLEEEEEMNSELVAKKRNLEDKCSSLKRDI 958

Query: 961  DDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEE 1020
            DDLELTL KVEKEKHATENKVKNL+EEM  L+E I+KLTKEKK+LQEAHQQTLDDLQ EE
Sbjct: 959  DDLELTLTKVEKEKHATENKVKNLSEEMTALEENISKLTKEKKSLQEAHQQTLDDLQVEE 1018

Query: 1021 DKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQ 1080
            DKVN L K   KLEQQ DDLEGSLEQEKKLR DLERAKRKLEGDLK++QESIMD+EN+KQ
Sbjct: 1019 DKVNGLIKINAKLEQQTDDLEGSLEQEKKLRADLERAKRKLEGDLKMSQESIMDLENDKQ 1078

Query: 1081 QLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEK 1140
            Q++EKLKKKEFE+S LQ+KI+DEQ   +Q QKKIKELQARIEELEEEIEAE   RAK EK
Sbjct: 1079 QIEEKLKKKEFELSQLQAKIDDEQVHSLQFQKKIKELQARIEELEEEIEAEHTLRAKIEK 1138

Query: 1141 QRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRK 1200
            QRSDL+RELEEISERLEEA GATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRK
Sbjct: 1139 QRSDLARELEEISERLEEASGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRK 1198

Query: 1201 KHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLED 1260
            K ADSVAELGEQIDNLQRVKQKLEKEKSE+KMEIDD+ASN+E +SK+K N+E+ CRT+ED
Sbjct: 1199 KQADSVAELGEQIDNLQRVKQKLEKEKSELKMEIDDMASNIEALSKSKSNIERTCRTVED 1258

Query: 1261 QLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEE 1320
            Q SE+K+K+E+Q +LI+DL  Q+ RLQT++GE S +++EKE+L+SQL++ KQA TQQ+EE
Sbjct: 1259 QFSEIKAKDEQQTQLIHDLNMQKARLQTQNGELSHRVEEKESLISQLTKSKQALTQQLEE 1318

Query: 1321 LKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTK 1380
            LKRQ+EEE KAKNA+AHALQSSRHDCDLLREQYEEEQE+KAELQRALSKAN+EVAQWRTK
Sbjct: 1319 LKRQMEEETKAKNAMAHALQSSRHDCDLLREQYEEEQEAKAELQRALSKANSEVAQWRTK 1378

Query: 1381 YETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVER 1440
            YETDAIQRTEELEEAKKKLAQRLQ AEE+ E  N+KCASLEKTKQRLQ EVEDLM D+ER
Sbjct: 1379 YETDAIQRTEELEEAKKKLAQRLQEAEENTETANSKCASLEKTKQRLQGEVEDLMRDLER 1438

Query: 1441 TNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQ 1500
            ++ ACA LDKKQRNFDK+LAEWKQK +E+ AELEA+QKE+RSL TELFK++NAYEE +DQ
Sbjct: 1439 SHTACATLDKKQRNFDKVLAEWKQKLDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQ 1498

Query: 1501 LETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHE 1560
            LETL+RENKNLQ+EISDLTEQIAE GK + E EK KK VEQEK +LQ ALEE E SLEHE
Sbjct: 1499 LETLRRENKNLQEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLEHE 1558

Query: 1561 EGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRL 1620
            E KILR+QLEL+QVKSE+DRK+ EKDEEI+QLKRN  R  E++QS LDAEIRSRNDA+RL
Sbjct: 1559 ESKILRVQLELSQVKSELDRKVIEKDEEIEQLKRNSQRAAEALQSVLDAEIRSRNDALRL 1618

Query: 1621 KKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMV 1680
            KKKMEGDLNEMEIQL H+NR  AE  ++ R  QG LKD+Q+HLDDALRS EDLKEQLA+V
Sbjct: 1619 KKKMEGDLNEMEIQLGHSNRQMAETQKHLRTVQGQLKDSQLHLDDALRSNEDLKEQLAIV 1678

Query: 1681 ERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDI 1740
            ERR  LL  E+EE++  LEQTER+R+++EQELLDAS+RVQLLH+QNTSLINTKKKLE DI
Sbjct: 1679 ERRNGLLLEELEEMKVALEQTERTRRLSEQELLDASDRVQLLHSQNTSLINTKKKLEADI 1738

Query: 1741 SQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQ 1800
            +Q Q E+E+ +QE+RNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKN+EQTVKDLQ
Sbjct: 1739 AQCQAEVENSIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQ 1798

Query: 1801 LRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQT 1860
             RLDEAEQLALKGGKKQIQKLE RVRELE E++ EQKR AEA+KG  K+ER+VKE+TYQ 
Sbjct: 1799 HRLDEAEQLALKGGKKQIQKLENRVRELENELDVEQKRGAEALKGAHKYERKVKEMTYQA 1858

Query: 1861 EEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAE 1920
            EED KNILRLQDLVDKLQAKVKSYKRQAEEAEEQ+NT L++ R++QHELEEA ERADIAE
Sbjct: 1859 EEDHKNILRLQDLVDKLQAKVKSYKRQAEEAEEQANTQLSRCRRVQHELEEAAERADIAE 1918

Query: 1921 SQVNKLRVKSREVHTKVISE 1940
            SQVNKLR KSR+V ++ + E
Sbjct: 1919 SQVNKLRAKSRDVGSQKMEE 1938


>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
            sapiens]
          Length = 1935

 Score = 3137 bits (8133), Expect = 0.0
 Identities = 1571/1938 (81%), Positives = 1769/1938 (91%), Gaps = 5/1938 (0%)

Query: 4    DSELAVFGEAAPFLRKSERERIEAQNRPFDAKTSVFVAEPKESFVKGTIQSREGGKVTVK 63
            DSE+AVFG AAP+LRKSE+ER+EAQ RPFD K  VFV + K+ FVK  I SREGGKVT +
Sbjct: 3    DSEMAVFGAAAPYLRKSEKERLEAQTRPFDLKKDVFVPDDKQEFVKAKIVSREGGKVTAE 62

Query: 64   TEGGATLTVKDDQVFPMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFC 123
            TE G T+TVK+DQV   NPPK+DKIEDMAM+T LHEPAVLYNLK+RY +WMIYTYSGLFC
Sbjct: 63   TEYGKTVTVKEDQVMQQNPPKFDKIEDMAMLTFLHEPAVLYNLKDRYGSWMIYTYSGLFC 122

Query: 124  VTVNPYKWLPVYKPEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGA 183
            VTVNPYKWLPVY PEVV AYRGKKR EAPPHIFSISDNAYQ+MLTDRENQSILITGESGA
Sbjct: 123  VTVNPYKWLPVYTPEVVAAYRGKKRSEAPPHIFSISDNAYQYMLTDRENQSILITGESGA 182

Query: 184  GKTVNTKRVIQYFATIAVTGEKKKEEITSGKIQGTLEDQIISANPLLEAFGNAKTVRNDN 243
            GKTVNTKRVIQYFA IA  G++ K++ + GK  GTLEDQII ANP LEAFGNAKTVRNDN
Sbjct: 183  GKTVNTKRVIQYFAVIAAIGDRSKKDQSPGK--GTLEDQIIQANPALEAFGNAKTVRNDN 240

Query: 244  SSRFGKFIRIHFGTTGKLASADIETYLLEKSRVVFQLKAERSYHIFYQITSNKKPELIEM 303
            SSRFGKFIRIHFG TGKLASADIETYLLEKSRV+FQLKAER YHIFYQI SNKKPEL++M
Sbjct: 241  SSRFGKFIRIHFGATGKLASADIETYLLEKSRVIFQLKAERDYHIFYQILSNKKPELLDM 300

Query: 304  LLITTNPYDYPFVSQGEISVASIDDQEELMATDSAIDILGFTNEEKVSIYKLTGAVMHYG 363
            LLIT NPYDY F+SQGE +VASIDD EELMATD+A D+LGFT+EEK S+YKLTGA+MH+G
Sbjct: 301  LLITNNPYDYAFISQGETTVASIDDAEELMATDNAFDVLGFTSEEKNSMYKLTGAIMHFG 360

Query: 364  NLKFKQKQREEQAEPDGTEVADKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTVEQV 423
            N+KFK KQREEQAEPDGTE ADK+AYL  LNSADLLK LC+PRVKVGNEYVTKGQ V+QV
Sbjct: 361  NMKFKLKQREEQAEPDGTEEADKSAYLMGLNSADLLKGLCHPRVKVGNEYVTKGQNVQQV 420

Query: 424  SNAVGALAKAVYEKMFLWMVARINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINF 483
              A GALAKAVYE+MF WMV RIN  L+TKQPRQYFIGVLDIAGFEIFDFNS EQLCINF
Sbjct: 421  IYATGALAKAVYERMFNWMVTRINATLETKQPRQYFIGVLDIAGFEIFDFNSFEQLCINF 480

Query: 484  TNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEECMF 543
            TNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDL ACI+LIEKPMGI SILEEECMF
Sbjct: 481  TNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLQACIDLIEKPMGIMSILEEECMF 540

Query: 544  PKATDTSFKNKLYDQHLGKSANFQKPKVVKGKAEAHFALIHYAGVVDYNITGWLEKNKDP 603
            PKATD +FK KL+D HLGKSANFQKP+ +KGK EAHF+LIHYAG+VDYNI GWL+KNKDP
Sbjct: 541  PKATDMTFKAKLFDNHLGKSANFQKPRNIKGKPEAHFSLIHYAGIVDYNIIGWLQKNKDP 600

Query: 604  LNETVVGLYQKSAMKTLAQLFSGAQTAEGEGAGGGAKKGGKKKGSSFQTVSALFRENLNK 663
            LNETVVGLYQKS++K L+ LF+    A+     G   KG  KKGSSFQTVSAL RENLNK
Sbjct: 601  LNETVVGLYQKSSLKLLSTLFANYAGADAPIEKG---KGKAKKGSSFQTVSALHRENLNK 657

Query: 664  LMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYAD 723
            LMTNLRSTHPHFVRCIIPNETK+PG M++ LV+HQLRCNGVLEGIRICRKGFP+RILY D
Sbjct: 658  LMTNLRSTHPHFVRCIIPNETKSPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGD 717

Query: 724  FKQRYKVLNASAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMR 783
            F+QRY++LN +AIPEGQFIDS+K +EKLL+S+DIDH QYKFGHTKVFFKAGLLGLLEEMR
Sbjct: 718  FRQRYRILNPAAIPEGQFIDSRKGAEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMR 777

Query: 784  DDKLAQLITRTQARCRGFLARVEYQRMVERREAIFCIQYNIRSFMNVKHWPWMKLFFKIK 843
            D++L+++ITR QA+ RG LAR+EY++++ERR+++  IQ+NIR+FM VK+WPWMKL+FKIK
Sbjct: 778  DERLSRIITRIQAQSRGVLARMEYKKLLERRDSLLVIQWNIRAFMGVKNWPWMKLYFKIK 837

Query: 844  PLLKSAETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEG 903
            PLLKSAE EKEMA+MKEEF ++K+ L KSEA+RKELEEKMV+LL+EKNDLQLQVQAE + 
Sbjct: 838  PLLKSAEREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDN 897

Query: 904  LADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDL 963
            LADAEERCDQLIK KIQLEAK+KE+ ER EDEEE+NAELTAKKRKLEDECSELK+DIDDL
Sbjct: 898  LADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDL 957

Query: 964  ELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKV 1023
            ELTLAKVEKEKHATENKVKNLTEEMAGLDE IAKLTKEKKALQEAHQQ LDDLQAEEDKV
Sbjct: 958  ELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKV 1017

Query: 1024 NTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLD 1083
            NTLTKAK+KLEQQVDDLEGSLEQEKK+RMDLERAKRKLEGDLKL QESIMD+EN+KQQLD
Sbjct: 1018 NTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLD 1077

Query: 1084 EKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRS 1143
            E+LKKK+FE++ L ++IEDEQALG QLQKK+KELQARIEELEEE+EAER +RAK EK RS
Sbjct: 1078 ERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRS 1137

Query: 1144 DLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHA 1203
            DLSRELEEISERLEEAGGATS QIEMNKKREAEFQKMRRDLEEATLQHEATAA LRKKHA
Sbjct: 1138 DLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHA 1197

Query: 1204 DSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLS 1263
            DSVAELGEQIDNLQRVKQKLEKEKSE K+E+DD+ SN+E + KAK NLEKMCRTLEDQ++
Sbjct: 1198 DSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMN 1257

Query: 1264 ELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKR 1323
            E +SK EE QR +NDLT+QR +LQTE+GE SRQLDEKEAL+SQL+RGK  +TQQ+E+LKR
Sbjct: 1258 EHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKR 1317

Query: 1324 QLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYET 1383
            QLEEE+KAKNALAHALQS+RHDCDLLREQYEEE E+KAELQR LSKAN+EVAQWRTKYET
Sbjct: 1318 QLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYET 1377

Query: 1384 DAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNA 1443
            DAIQRTEELEEAKKKLAQRLQ AEE VEAVNAKC+SLEKTK RLQNE+EDLM+DVER+NA
Sbjct: 1378 DAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNA 1437

Query: 1444 ACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLET 1503
            A AALDKKQRNFDKILAEWKQK EE+ +ELE+SQKEARSL TELFK+KNAYEESL+ LET
Sbjct: 1438 AAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLET 1497

Query: 1504 LKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGK 1563
             KRENKNLQ+EISDLTEQ+   GK IHELEK++KQ+E EK ELQ+ALEEAEASLEHEEGK
Sbjct: 1498 FKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGK 1557

Query: 1564 ILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKK 1623
            ILR QLE NQ+K+E++RK+AEKDEE++Q KRNH+R+V+S+Q++LDAE RSRN+A+R+KKK
Sbjct: 1558 ILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKK 1617

Query: 1624 MEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERR 1683
            MEGDLNEMEIQL+HANRMAAEA +  ++ Q +LKDTQI LDDA+R+ +DLKE +A+VERR
Sbjct: 1618 MEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERR 1677

Query: 1684 ANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQM 1743
             NLLQAE+EELRA +EQTERSRK+AEQEL++ SERVQLLH+QNTSLIN KKK++ D+SQ+
Sbjct: 1678 NNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQL 1737

Query: 1744 QGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRL 1803
            Q E+E+ +QE RNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQT+KDLQ RL
Sbjct: 1738 QTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRL 1797

Query: 1804 DEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEED 1863
            DEAEQ+ALKGGKKQ+QKLEARVRELE E+E+EQKRNAE+VKG+RK ERR+KELTYQTEED
Sbjct: 1798 DEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEED 1857

Query: 1864 RKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAESQV 1923
            RKN+LRLQDLVDKLQ KVK+YKRQAEEAEEQ+NTNL+KFRK+QHEL+EAEERADIAESQV
Sbjct: 1858 RKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQV 1917

Query: 1924 NKLRVKSREVHTKVISEE 1941
            NKLR KSR++ TK ++EE
Sbjct: 1918 NKLRAKSRDIGTKGLNEE 1935


>gi|156104908 myosin heavy chain 6 [Homo sapiens]
          Length = 1939

 Score = 3108 bits (8058), Expect = 0.0
 Identities = 1558/1934 (80%), Positives = 1754/1934 (90%), Gaps = 3/1934 (0%)

Query: 3    SDSELAVFGEAAPFLRKSERERIEAQNRPFDAKTSVFVAEPKESFVKGTIQSREGGKVTV 62
            +D+++A FG AA +LRKSE+ER+EAQ RPFD +T  FV + KE FVK  I SREGGKV  
Sbjct: 2    TDAQMADFGAAAQYLRKSEKERLEAQTRPFDIRTECFVPDDKEEFVKAKILSREGGKVIA 61

Query: 63   KTEGGATLTVKDDQVFPMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLF 122
            +TE G T+TVK+DQV   NPPK+DKIEDMAM+T LHEPAVL+NLKERYAAWMIYTYSGLF
Sbjct: 62   ETENGKTVTVKEDQVLQQNPPKFDKIEDMAMLTFLHEPAVLFNLKERYAAWMIYTYSGLF 121

Query: 123  CVTVNPYKWLPVYKPEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESG 182
            CVTVNPYKWLPVY  EVV AYRGKKR EAPPHIFSISDNAYQ+MLTDRENQSILITGESG
Sbjct: 122  CVTVNPYKWLPVYNAEVVAAYRGKKRSEAPPHIFSISDNAYQYMLTDRENQSILITGESG 181

Query: 183  AGKTVNTKRVIQYFATIAVTGEKKKEEITSGKIQGTLEDQIISANPLLEAFGNAKTVRND 242
            AGKTVNTKRVIQYFA+IA  G++ K++  +   +GTLEDQII ANP LEAFGNAKTVRND
Sbjct: 182  AGKTVNTKRVIQYFASIAAIGDRGKKDNANAN-KGTLEDQIIQANPALEAFGNAKTVRND 240

Query: 243  NSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVVFQLKAERSYHIFYQITSNKKPELIE 302
            NSSRFGKFIRIHFG TGKLASADIETYLLEKSRV+FQLKAER+YHIFYQI SNKKPEL++
Sbjct: 241  NSSRFGKFIRIHFGATGKLASADIETYLLEKSRVIFQLKAERNYHIFYQILSNKKPELLD 300

Query: 303  MLLITTNPYDYPFVSQGEISVASIDDQEELMATDSAIDILGFTNEEKVSIYKLTGAVMHY 362
            MLL+T NPYDY FVSQGE+SVASIDD EELMATDSA D+LGFT+EEK  +YKLTGA+MHY
Sbjct: 301  MLLVTNNPYDYAFVSQGEVSVASIDDSEELMATDSAFDVLGFTSEEKAGVYKLTGAIMHY 360

Query: 363  GNLKFKQKQREEQAEPDGTEVADKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTVEQ 422
            GN+KFKQKQREEQAEPDGTE ADK+AYL  LNSADLLK LC+PRVKVGNEYVTKGQ+V+Q
Sbjct: 361  GNMKFKQKQREEQAEPDGTEDADKSAYLMGLNSADLLKGLCHPRVKVGNEYVTKGQSVQQ 420

Query: 423  VSNAVGALAKAVYEKMFLWMVARINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCIN 482
            V  ++GALAKAVYEKMF WMV RIN  L+TKQPRQYFIGVLDIAGFEIFDFNS EQLCIN
Sbjct: 421  VYYSIGALAKAVYEKMFNWMVTRINATLETKQPRQYFIGVLDIAGFEIFDFNSFEQLCIN 480

Query: 483  FTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEECM 542
            FTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDL ACI+LIEKPMGI SILEEECM
Sbjct: 481  FTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLQACIDLIEKPMGIMSILEEECM 540

Query: 543  FPKATDTSFKNKLYDQHLGKSANFQKPKVVKGKAEAHFALIHYAGVVDYNITGWLEKNKD 602
            FPKATD +FK KLYD HLGKS NFQKP+ +KGK EAHF+LIHYAG VDYNI GWLEKNKD
Sbjct: 541  FPKATDMTFKAKLYDNHLGKSNNFQKPRNIKGKQEAHFSLIHYAGTVDYNILGWLEKNKD 600

Query: 603  PLNETVVGLYQKSAMKTLAQLFSGAQTAEGEGAGGGAKKGGKKKGSSFQTVSALFRENLN 662
            PLNETVV LYQKS++K +A LFS   TA+      G  KGGKKKGSSFQTVSAL RENLN
Sbjct: 601  PLNETVVALYQKSSLKLMATLFSSYATADT--GDSGKSKGGKKKGSSFQTVSALHRENLN 658

Query: 663  KLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYA 722
            KLMTNLR+THPHFVRCIIPNE K PG M++ LV+HQLRCNGVLEGIRICRKGFP+RILY 
Sbjct: 659  KLMTNLRTTHPHFVRCIIPNERKAPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYG 718

Query: 723  DFKQRYKVLNASAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEM 782
            DF+QRY++LN  AIPEGQFIDS+K +EKLL+S+DIDH QYKFGHTKVFFKAGLLGLLEEM
Sbjct: 719  DFRQRYRILNPVAIPEGQFIDSRKGTEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEM 778

Query: 783  RDDKLAQLITRTQARCRGFLARVEYQRMVERREAIFCIQYNIRSFMNVKHWPWMKLFFKI 842
            RD++L+++ITR QA+ RG L R+E++++VERR+A+  IQ+NIR+FM VK+WPWMKL+FKI
Sbjct: 779  RDERLSRIITRMQAQARGQLMRIEFKKIVERRDALLVIQWNIRAFMGVKNWPWMKLYFKI 838

Query: 843  KPLLKSAETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAE 902
            KPLLKSAETEKEMATMKEEF +IK+ L KSEA+RKELEEKMV+LL+EKNDLQLQVQAE +
Sbjct: 839  KPLLKSAETEKEMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQD 898

Query: 903  GLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDD 962
             L DAEERCDQLIK KIQLEAK+KE+ ER EDEEE+NAELTAKKRKLEDECSELKKDIDD
Sbjct: 899  NLNDAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDIDD 958

Query: 963  LELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDK 1022
            LELTLAKVEKEKHATENKVKNLTEEMAGLDE IAKLTKEKKALQEAHQQ LDDLQ EEDK
Sbjct: 959  LELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQVEEDK 1018

Query: 1023 VNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQL 1082
            VN+L+K+K+KLEQQVDDLEGSLEQEKK+RMDLERAKRKLEGDLKL QESIMD+EN+K QL
Sbjct: 1019 VNSLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQL 1078

Query: 1083 DEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQR 1142
            +EKLKKKEF+I+   SKIEDEQ L +QLQKK+KE QARIEELEEE+EAER +RAK EK R
Sbjct: 1079 EEKLKKKEFDINQQNSKIEDEQVLALQLQKKLKENQARIEELEEELEAERTARAKVEKLR 1138

Query: 1143 SDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKH 1202
            SDLSRELEEISERLEEAGGATS QIEMNKKREAEFQKMRRDLEEATLQHEATAA LRKKH
Sbjct: 1139 SDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKH 1198

Query: 1203 ADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQL 1262
            ADSVAELGEQIDNLQRVKQKLEKEKSE K+E+DD+ SN+E + KAK NLEK+ RTLEDQ 
Sbjct: 1199 ADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQA 1258

Query: 1263 SELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELK 1322
            +E + K EE QR +ND T QR +LQTE+GE +RQL+EKEAL+SQL+RGK ++TQQ+E+LK
Sbjct: 1259 NEYRVKLEEAQRSLNDFTTQRAKLQTENGELARQLEEKEALISQLTRGKLSYTQQMEDLK 1318

Query: 1323 RQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYE 1382
            RQLEEE KAKNALAHALQS+RHDCDLLREQYEEE E+KAELQR LSKAN+EVAQWRTKYE
Sbjct: 1319 RQLEEEGKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYE 1378

Query: 1383 TDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTN 1442
            TDAIQRTEELEEAKKKLAQRLQ AEE VEAVNAKC+SLEKTK RLQNE+EDLM+DVER+N
Sbjct: 1379 TDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSN 1438

Query: 1443 AACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLE 1502
            AA AALDKKQRNFDKILAEWKQK EE+ +ELE+SQKEARSL TELFK+KNAYEESL+ LE
Sbjct: 1439 AAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLE 1498

Query: 1503 TLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEG 1562
            T KRENKNLQ+EISDLTEQ+ EGGK +HELEK++KQ+E EK ELQ+ALEEAEASLEHEEG
Sbjct: 1499 TFKRENKNLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQSALEEAEASLEHEEG 1558

Query: 1563 KILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKK 1622
            KILR QLE NQ+K+E++RK+AEKDEE++Q KRNH R+V+S+Q++LDAE RSRN+ +R+KK
Sbjct: 1559 KILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKK 1618

Query: 1623 KMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVER 1682
            KMEGDLNEMEIQL+HANRMAAEA +  ++ Q +LKDTQI LDDA+R+ +DLKE +A+VER
Sbjct: 1619 KMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVER 1678

Query: 1683 RANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQ 1742
            R NLLQAE+EELRA +EQTERSRK+AEQEL++ SERVQLLH+QNTSLIN KKK+E+D++Q
Sbjct: 1679 RNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMESDLTQ 1738

Query: 1743 MQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLR 1802
            +Q E+E+ +QE RNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQT+KDLQ R
Sbjct: 1739 LQSEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHR 1798

Query: 1803 LDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEE 1862
            LDEAEQ+ALKGGKKQ+QKLEARVRELEGE+E+EQKRNAE+VKG+RK ERR+KELTYQTEE
Sbjct: 1799 LDEAEQIALKGGKKQLQKLEARVRELEGELEAEQKRNAESVKGMRKSERRIKELTYQTEE 1858

Query: 1863 DRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAESQ 1922
            D+KN+LRLQDLVDKLQ KVK+YKRQAEEAEEQ+NTNL+KFRK+QHEL+EAEERADIAESQ
Sbjct: 1859 DKKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQ 1918

Query: 1923 VNKLRVKSREVHTK 1936
            VNKLR KSR++  K
Sbjct: 1919 VNKLRAKSRDIGAK 1932



 Score =  187 bits (475), Expect = 9e-47
 Identities = 197/868 (22%), Positives = 377/868 (43%), Gaps = 121/868 (13%)

Query: 1088 KKEFEISNLQSKIEDEQALGIQLQK--KIKELQARIEELEEEIEAERASRAKAEKQRSDL 1145
            K  F+I  L    E E+ +    ++  +IKE   + E   +E+E +  S  +   +++DL
Sbjct: 833  KLYFKIKPLLKSAETEKEMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQ---EKNDL 889

Query: 1146 SRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADS 1205
              +++   + L +A       I+   + EA+ ++M   LE+     E   A L  K    
Sbjct: 890  QLQVQAEQDNLNDAEERCDQLIKNKIQLEAKVKEMNERLED----EEEMNAELTAK---- 941

Query: 1206 VAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSEL 1265
                          K+KLE E SE+K +IDDL   +  V K K   E   + L ++++ L
Sbjct: 942  --------------KRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGL 987

Query: 1266 KSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQL 1325
                     +I  LT ++  LQ    +    L  +E  V+ LS+ K    QQ+++L+  L
Sbjct: 988  -------DEIIAKLTKEKKALQEAHQQALDDLQVEEDKVNSLSKSKVKLEQQVDDLEGSL 1040

Query: 1326 EEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDA 1385
            E+E K +  L  A +    D  L +E   + +  K +L+  L K   ++ Q  +K E + 
Sbjct: 1041 EQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQ 1100

Query: 1386 IQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAAC 1445
            +   + L++  K+   R++  EE +EA     A +EK +  L  E+E++   +E    A 
Sbjct: 1101 VLALQ-LQKKLKENQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGAT 1159

Query: 1446 AAL----DKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQL 1501
            +       K++  F K+  + ++   +  A   A +K+      EL        E +D L
Sbjct: 1160 SVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAEL-------GEQIDNL 1212

Query: 1502 ETLK----RENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASL 1557
            + +K    +E    + E+ D+T  + +  K    LEK+ + +E +  E +  LEEA+ SL
Sbjct: 1213 QRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRSL 1272

Query: 1558 EHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDA 1617
                 +  ++Q E      E+ R++ EK+  I QL R  +   + M+             
Sbjct: 1273 NDFTTQRAKLQTE----NGELARQLEEKEALISQLTRGKLSYTQQMED------------ 1316

Query: 1618 IRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQL 1677
              LK+++E +          A    A AL++ R+   +L++           + + K +L
Sbjct: 1317 --LKRQLEEE--------GKAKNALAHALQSARHDCDLLREQY-------EEETEAKAEL 1359

Query: 1678 AMVERRANLLQA------EIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLIN 1731
              V  +AN   A      E + ++ T E  E  +K+A Q L DA E V+ ++ + +SL  
Sbjct: 1360 QRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLA-QRLQDAEEAVEAVNAKCSSLEK 1418

Query: 1732 TKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKN 1791
            TK +L       Q E+ED++ +   +   A                     A L++ ++N
Sbjct: 1419 TKHRL-------QNEIEDLMVDVERSNAAA---------------------AALDKKQRN 1450

Query: 1792 MEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKH-E 1850
             ++ + + + + +E+ Q  L+  +K+ + L   + +L+   E E   + E  K   K+ +
Sbjct: 1451 FDKILAEWKQKYEES-QSELESSQKEARSLSTELFKLKNAYE-ESLEHLETFKRENKNLQ 1508

Query: 1851 RRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELE 1910
              + +LT Q  E  KN+  L+ +  +L+ +    +   EEAE        K  + Q E  
Sbjct: 1509 EEISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFN 1568

Query: 1911 EAEERADIAESQVNKLRVKSREVHTKVI 1938
            + +   +   ++ ++   +++  H +V+
Sbjct: 1569 QIKAEIERKLAEKDEEMEQAKRNHQRVV 1596



 Score = 65.1 bits (157), Expect = 6e-10
 Identities = 62/313 (19%), Positives = 137/313 (43%), Gaps = 44/313 (14%)

Query: 848  SAETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADA 907
            +AE +K++ +++   +  + +L  +     +L+E +  + +  N LQ +++ E   + + 
Sbjct: 1638 AAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELE-ELRAVVEQ 1696

Query: 908  EERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTL 967
             ER  +L       E ++ E +ER +     N  L  +K+K+E + ++L+ ++++     
Sbjct: 1697 TERSRKLA------EQELIETSERVQLLHSQNTSLINQKKKMESDLTQLQSEVEEAVQEC 1750

Query: 968  AKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLT 1027
               E++          + EE+    +T A L + KK ++    QT+ DLQ   D+   + 
Sbjct: 1751 RNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNME----QTIKDLQHRLDEAEQIA 1806

Query: 1028 -----KAKIKLEQQVDDLEGSL----------------------------EQEKKLRMDL 1054
                 K   KLE +V +LEG L                            E++KK  + L
Sbjct: 1807 LKGGKKQLQKLEARVRELEGELEAEQKRNAESVKGMRKSERRIKELTYQTEEDKKNLLRL 1866

Query: 1055 ERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKI 1114
            +    KL+  +K  +    + E +      K +K + E+   + + +  ++   +L+ K 
Sbjct: 1867 QDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKS 1926

Query: 1115 KELQARIEELEEE 1127
            +++ A+ +  +EE
Sbjct: 1927 RDIGAKQKMHDEE 1939



 Score = 33.9 bits (76), Expect = 1.6
 Identities = 24/99 (24%), Positives = 46/99 (46%), Gaps = 4/99 (4%)

Query: 1843 VKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKF 1902
            +K L K     KE+    EE      R+++ ++K +A+ K  + +     ++ N    + 
Sbjct: 838  IKPLLKSAETEKEMATMKEE----FGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQV 893

Query: 1903 RKLQHELEEAEERADIAESQVNKLRVKSREVHTKVISEE 1941
            +  Q  L +AEER D       +L  K +E++ ++  EE
Sbjct: 894  QAEQDNLNDAEERCDQLIKNKIQLEAKVKEMNERLEDEE 932


>gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta [Homo
            sapiens]
          Length = 1983

 Score = 2609 bits (6762), Expect = 0.0
 Identities = 1309/1932 (67%), Positives = 1619/1932 (83%), Gaps = 6/1932 (0%)

Query: 6    ELAVFGEAAPFLRKSERERIEAQNRPFDAKTSVFVAEPKESFVKGTIQSRE-GGKVTVKT 64
            +++  GE+A +LR+  +E  +    P+D K  V+V + ++++V+  ++S   GG+VTV+T
Sbjct: 45   DVSELGESARYLRQGYQEMTKVHTIPWDGKKRVWVPDEQDAYVEAEVKSEATGGRVTVET 104

Query: 65   EGGATLTVKDDQVFPMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCV 124
            +    L V++ ++ PMNPP++D +EDMAMMTHL+E +VL+NL++RYA WMIYTYSGLFCV
Sbjct: 105  KDQKVLMVREAELQPMNPPRFDLLEDMAMMTHLNEASVLHNLRQRYARWMIYTYSGLFCV 164

Query: 125  TVNPYKWLPVYKPEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAG 184
            T+NPYKWLPVY   VV AY+GK+R ++PPHI++++DNAY  ML +R+NQS+LITGESGAG
Sbjct: 165  TINPYKWLPVYTASVVAAYKGKRRSDSPPHIYAVADNAYNDMLRNRDNQSMLITGESGAG 224

Query: 185  KTVNTKRVIQYFATIAVTGEK--KKEEITSGKIQGTLEDQIISANPLLEAFGNAKTVRND 242
            KTVNTKRVIQYFA +A  G+   KK +  + K  GTLEDQII ANP +EAFGNAKT+RND
Sbjct: 225  KTVNTKRVIQYFAIVAALGDGPGKKAQFLATKTGGTLEDQIIEANPAMEAFGNAKTLRND 284

Query: 243  NSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVVFQLKAERSYHIFYQITSNKKPELIE 302
            NSSRFGKFIRIHFG +GKLASADI++YLLEKSRV+FQL  ERSYH++YQI S +KPEL +
Sbjct: 285  NSSRFGKFIRIHFGPSGKLASADIDSYLLEKSRVIFQLPGERSYHVYYQILSGRKPELQD 344

Query: 303  MLLITTNPYDYPFVSQGEISVASIDDQEELMATDSAIDILGFTNEEKVSIYKLTGAVMHY 362
            MLL++ NPYDY F SQG I+V +++D EEL+ATD A+DILGF+ +EK + YK+ GA++H+
Sbjct: 345  MLLLSMNPYDYHFCSQGVITVDNMNDGEELIATDHAMDILGFSVDEKCACYKIVGALLHF 404

Query: 363  GNLKFKQKQREEQAEPDGTEVADKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTVEQ 422
            GN+KFKQKQREEQAE DGTE ADKAAYL  ++S DLLK L +PRV+VGNEYVTKGQ+VEQ
Sbjct: 405  GNMKFKQKQREEQAEADGTESADKAAYLMGVSSGDLLKGLLHPRVRVGNEYVTKGQSVEQ 464

Query: 423  VSNAVGALAKAVYEKMFLWMVARINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCIN 482
            V  AVGALAKA Y+++F W+V+RINQ LDTK PRQ+FIGVLDIAGFEIF+FNS EQLCIN
Sbjct: 465  VVFAVGALAKATYDRLFRWLVSRINQTLDTKLPRQFFIGVLDIAGFEIFEFNSFEQLCIN 524

Query: 483  FTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEECM 542
            FTNEKLQQFFN HMFVLEQEEYK+EGI+W FIDFG+DL  CI+LIEKP+GI SILEEECM
Sbjct: 525  FTNEKLQQFFNQHMFVLEQEEYKREGIDWVFIDFGLDLQPCIDLIEKPLGILSILEEECM 584

Query: 543  FPKATDTSFKNKLYDQHLGKSANFQKPKV-VKGKAEAHFALIHYAGVVDYNITGWLEKNK 601
            FPKA+D SF+ KLYD H GKS NFQ+P+   K K +AHF ++HYAGVV Y+I GWLEKNK
Sbjct: 585  FPKASDASFRAKLYDNHAGKSPNFQQPRPDKKRKYQAHFEVVHYAGVVPYSIVGWLEKNK 644

Query: 602  DPLNETVVGLYQKSAMKTLAQLFSG-AQTAEGEGAGGGAKKGGKKKGSSFQTVSALFREN 660
            DPLNETVV ++QKS  + LA L+   A +   E    G K+  +KK +SFQTVS L +EN
Sbjct: 645  DPLNETVVPIFQKSQNRLLATLYENYAGSCSTEPPKSGVKEK-RKKAASFQTVSQLHKEN 703

Query: 661  LNKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRIL 720
            LNKLMTNLR+T PHFVRCI+PNE KTPG M+  LVLHQLRCNGVLEGIRICR+GFP+R+L
Sbjct: 704  LNKLMTNLRATQPHFVRCIVPNENKTPGVMDAFLVLHQLRCNGVLEGIRICRQGFPNRLL 763

Query: 721  YADFKQRYKVLNASAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLE 780
            Y DF+QRY++LN SAIP+  F+DS+KA+EKLL S+D+DHTQY+FGHTKVFFKAGLLG+LE
Sbjct: 764  YTDFRQRYRILNPSAIPDDTFMDSRKATEKLLGSLDLDHTQYQFGHTKVFFKAGLLGVLE 823

Query: 781  EMRDDKLAQLITRTQARCRGFLARVEYQRMVERREAIFCIQYNIRSFMNVKHWPWMKLFF 840
            E+RD +LA+++T  QAR RG L R+EYQR++  R+A+F IQ+NIR+F  VK+W WMKLFF
Sbjct: 824  ELRDQRLAKVLTLLQARSRGRLMRLEYQRLLGGRDALFTIQWNIRAFNAVKNWSWMKLFF 883

Query: 841  KIKPLLKSAETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAE 900
            K+KPLL+SA+ E+E+A ++ E + ++  LA +EAKR+ELEE  V++ +EKNDL LQ+QAE
Sbjct: 884  KMKPLLRSAQAEEELAALRAELRGLRGALAAAEAKRQELEETHVSITQEKNDLALQLQAE 943

Query: 901  AEGLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDI 960
             + LADAEERC  LIK+K+QLE K+KE++ER EDEEE+NA+L A++RKLEDEC+ELKKDI
Sbjct: 944  QDNLADAEERCHLLIKSKVQLEGKVKELSERLEDEEEVNADLAARRRKLEDECTELKKDI 1003

Query: 961  DDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEE 1020
            DDL+LTLAK EKEK ATENKVKNLTEEMA LDE++A+LTKEKKALQEAHQQ L DLQAEE
Sbjct: 1004 DDLKLTLAKAEKEKQATENKVKNLTEEMAALDESVARLTKEKKALQEAHQQALGDLQAEE 1063

Query: 1021 DKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQ 1080
            D+V+ LTKAK++LEQQV+DLE SLEQEKKLRMD ERAKRKLEGDLKL QES+ D   +KQ
Sbjct: 1064 DRVSALTKAKLRLEQQVEDLECSLEQEKKLRMDTERAKRKLEGDLKLTQESVADAAQDKQ 1123

Query: 1081 QLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEK 1140
            QL+EKLKKK+ E+S L  ++EDEQ LG Q+QKKIKELQAR EELEEE+EAERA+RA+ EK
Sbjct: 1124 QLEEKLKKKDSELSQLSLRVEDEQLLGAQMQKKIKELQARAEELEEELEAERAARARVEK 1183

Query: 1141 QRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRK 1200
            QR++ +RELEE+SERLEEAGGA++ Q E  +KREAE  ++RR+LEEA L+HEAT A LR+
Sbjct: 1184 QRAEAARELEELSERLEEAGGASAGQREGCRKREAELGRLRRELEEAALRHEATVAALRR 1243

Query: 1201 KHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLED 1260
            K A+  AELGEQ+D+LQRV+QKLEKEKSE++ME+DDLA+NVET+++AK + EK+CRT ED
Sbjct: 1244 KQAEGAAELGEQVDSLQRVRQKLEKEKSELRMEVDDLAANVETLTRAKASAEKLCRTYED 1303

Query: 1261 QLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEE 1320
            QLSE K K EE QR + D + QRGRLQTESGE SR L+EKE L+SQLSRGK    Q +EE
Sbjct: 1304 QLSEAKIKVEELQRQLADASTQRGRLQTESGELSRLLEEKECLISQLSRGKALAAQSLEE 1363

Query: 1321 LKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTK 1380
            L+RQLEEE KAK+ALAHA+Q+ RHDCDLLREQ+EEE E++AELQR LSKAN EVAQWR+K
Sbjct: 1364 LRRQLEEESKAKSALAHAVQALRHDCDLLREQHEEEAEAQAELQRLLSKANAEVAQWRSK 1423

Query: 1381 YETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVER 1440
            YE DAIQRTEELEEAKKKLA RLQ AEE VEA NAKC+SLEK K RLQ E ED+ L++ER
Sbjct: 1424 YEADAIQRTEELEEAKKKLALRLQEAEEGVEAANAKCSSLEKAKLRLQTESEDVTLELER 1483

Query: 1441 TNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQ 1500
              +A AALDKKQR+ ++ L E +++ EE   ELEA+Q+E+R LGTELF++++ +EE+L+ 
Sbjct: 1484 ATSAAAALDKKQRHLERALEERRRQEEEMQRELEAAQRESRGLGTELFRLRHGHEEALEA 1543

Query: 1501 LETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHE 1560
            LETLKRENKNLQ+EISDLT+Q++  GK I ELEK KK +E EK E+QAALEEAE +LE E
Sbjct: 1544 LETLKRENKNLQEEISDLTDQVSLSGKSIQELEKTKKALEGEKSEIQAALEEAEGALELE 1603

Query: 1561 EGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRL 1620
            E K LRIQLEL+QVK+EVDRK+AEKDEE   L+RNH R VES+Q++LDAE R+RN+A+RL
Sbjct: 1604 ETKTLRIQLELSQVKAEVDRKLAEKDEECANLRRNHQRAVESLQASLDAETRARNEALRL 1663

Query: 1621 KKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMV 1680
            KKKMEGDLN++E+QL HA R A EA    R  Q  LK+ Q   D+  R   +L EQ   +
Sbjct: 1664 KKKMEGDLNDLELQLGHATRQATEAQAATRLMQAQLKEEQAGRDEEQRLAAELHEQAQAL 1723

Query: 1681 ERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDI 1740
            ERRA+LL AE+EELRA LEQ ERSR++AEQELL+A+ER+ LLH+QNT L+N KKKLE D+
Sbjct: 1724 ERRASLLAAELEELRAALEQGERSRRLAEQELLEATERLNLLHSQNTGLLNQKKKLEADL 1783

Query: 1741 SQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQ 1800
            +Q+ GE+E+  QE R AEEKAKKAITDAAMMAEELKKEQDTSAHLERMKK +EQTV++LQ
Sbjct: 1784 AQLSGEVEEAAQERREAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKTLEQTVRELQ 1843

Query: 1801 LRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQT 1860
             RL+EAEQ AL+GGKKQ+QKLEA+VRELE E+++EQK++AEA+KG+RKHERRVKEL YQ 
Sbjct: 1844 ARLEEAEQAALRGGKKQVQKLEAKVRELEAELDAEQKKHAEALKGVRKHERRVKELAYQA 1903

Query: 1861 EEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAE 1920
            EEDRKN+ R+QDLVDKLQ+KVKSYKRQ EEAE+Q+NTNLAK+RK QHEL++AEERAD+AE
Sbjct: 1904 EEDRKNLARMQDLVDKLQSKVKSYKRQFEEAEQQANTNLAKYRKAQHELDDAEERADMAE 1963

Query: 1921 SQVNKLRVKSRE 1932
            +Q NKLR ++R+
Sbjct: 1964 TQANKLRARTRD 1975



 Score =  218 bits (555), Expect = 5e-56
 Identities = 203/926 (21%), Positives = 424/926 (45%), Gaps = 56/926 (6%)

Query: 1031 IKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQ-------ESIMDIENEKQQLD 1083
            +KL  ++  L  S + E++L   L    R L G L  A+       E+ + I  EK  L 
Sbjct: 879  MKLFFKMKPLLRSAQAEEELAA-LRAELRGLRGALAAAEAKRQELEETHVSITQEKNDLA 937

Query: 1084 EKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRA-KAEKQR 1142
             +L+ ++  +++ + +        +QL+ K+KEL  R+E+ EEE+ A+ A+R  K E + 
Sbjct: 938  LQLQAEQDNLADAEERCHLLIKSKVQLEGKVKELSERLED-EEEVNADLAARRRKLEDEC 996

Query: 1143 SDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKH 1202
            ++L ++++++   L +A           K+++A   K++   EE     E+ A   ++K 
Sbjct: 997  TELKKDIDDLKLTLAKA----------EKEKQATENKVKNLTEEMAALDESVARLTKEKK 1046

Query: 1203 ADSVAELGEQIDNLQRVKQK---LEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLE 1259
            A   A   + + +LQ  + +   L K K  ++ +++DL  ++E   K + + E+  R LE
Sbjct: 1047 ALQEAHQ-QALGDLQAEEDRVSALTKAKLRLEQQVEDLECSLEQEKKLRMDTERAKRKLE 1105

Query: 1260 DQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIE 1319
              L   +    +  +    L  +  +  +E  + S ++++++ L +Q+ +  +    + E
Sbjct: 1106 GDLKLTQESVADAAQDKQQLEEKLKKKDSELSQLSLRVEDEQLLGAQMQKKIKELQARAE 1165

Query: 1320 ELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRT 1379
            EL+ +LE E  A+  +      +  + + L E+ EE   + A  +    K   E+ + R 
Sbjct: 1166 ELEEELEAERAARARVEKQRAEAARELEELSERLEEAGGASAGQREGCRKREAELGRLRR 1225

Query: 1380 KYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVE 1439
            + E  A++    +   ++K A+      E V+++      LEK K  L+ EV+DL  +VE
Sbjct: 1226 ELEEAALRHEATVAALRRKQAEGAAELGEQVDSLQRVRQKLEKEKSELRMEVDDLAANVE 1285

Query: 1440 RTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLD 1499
                A A+ +K  R ++  L+E K K EE   +L  +  +   L TE  ++    EE   
Sbjct: 1286 TLTRAKASAEKLCRTYEDQLSEAKIKVEELQRQLADASTQRGRLQTESGELSRLLEEKEC 1345

Query: 1500 QLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEH 1559
             +  L R      Q + +L  Q+ E  K    L    + +  + C+L     E EA  + 
Sbjct: 1346 LISQLSRGKALAAQSLEELRRQLEEESKAKSALAHAVQALRHD-CDLLREQHEEEAEAQA 1404

Query: 1560 EEGKIL-RIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAI 1618
            E  ++L +   E+ Q +S+ +    ++ EE+++ K+     ++  +  ++A     +   
Sbjct: 1405 ELQRLLSKANAEVAQWRSKYEADAIQRTEELEEAKKKLALRLQEAEEGVEAANAKCSSLE 1464

Query: 1619 RLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLA 1678
            + K +++ +  ++ ++L  A   AA   +  R+ +  L++ +       R +E+++ +L 
Sbjct: 1465 KAKLRLQTESEDVTLELERATSAAAALDKKQRHLERALEERR-------RQEEEMQRELE 1517

Query: 1679 MVERRANLLQAEI-------EELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLIN 1731
              +R +  L  E+       EE    LE  +R  K  ++E+ D +++V L       L  
Sbjct: 1518 AAQRESRGLGTELFRLRHGHEEALEALETLKRENKNLQEEISDLTDQVSLSGKSIQELEK 1577

Query: 1732 TKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEEL-KKEQDTSAHLERMKK 1790
            TKK LE + S++Q  +E+        E K  +   + + +  E+ +K  +       +++
Sbjct: 1578 TKKALEGEKSEIQAALEEAEGALELEETKTLRIQLELSQVKAEVDRKLAEKDEECANLRR 1637

Query: 1791 NMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHE 1850
            N ++ V+ LQ  LD AE  A     +  +K+E  + +LE ++    ++  EA    R  +
Sbjct: 1638 NHQRAVESLQASLD-AETRARNEALRLKKKMEGDLNDLELQLGHATRQATEAQAATRLMQ 1696

Query: 1851 RRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELE 1910
             ++KE     +E+++    L +              QA+  E +++   A+  +L+  LE
Sbjct: 1697 AQLKEEQAGRDEEQRLAAELHE--------------QAQALERRASLLAAELEELRAALE 1742

Query: 1911 EAEERADIAESQVNKLRVKSREVHTK 1936
            + E    +AE ++ +   +   +H++
Sbjct: 1743 QGERSRRLAEQELLEATERLNLLHSQ 1768



 Score =  144 bits (363), Expect = 8e-34
 Identities = 188/810 (23%), Positives = 336/810 (41%), Gaps = 96/810 (11%)

Query: 1177 FQKMRRDLEEATLQHEATA--ATLRK-KHADSVAELGEQIDNLQRVKQKLEKEKSEMKME 1233
            F KM+  L  A  + E  A  A LR  + A + AE   Q   L+     + +EK+++ ++
Sbjct: 882  FFKMKPLLRSAQAEEELAALRAELRGLRGALAAAEAKRQ--ELEETHVSITQEKNDLALQ 939

Query: 1234 IDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEF 1293
            +     N+    +    L K    LE ++ EL  + E+++ +  DL A+R +L+ E  E 
Sbjct: 940  LQAEQDNLADAEERCHLLIKSKVQLEGKVKELSERLEDEEEVNADLAARRRKLEDECTEL 999

Query: 1294 SRQLDEKEALVSQLSRGKQAFTQQIEELKRQ---LEEEI----KAKNALAHALQSSRHDC 1346
             + +D+ +  +++  + KQA   +++ L  +   L+E +    K K AL  A Q +  D 
Sbjct: 1000 KKDIDDLKLTLAKAEKEKQATENKVKNLTEEMAALDESVARLTKEKKALQEAHQQALGDL 1059

Query: 1347 DLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTE---ELEEAKKKLAQRL 1403
                 Q EE++ S      AL+KA   + Q     E    Q  +   + E AK+KL   L
Sbjct: 1060 -----QAEEDRVS------ALTKAKLRLEQQVEDLECSLEQEKKLRMDTERAKRKLEGDL 1108

Query: 1404 QAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWK 1463
            +  +E V         LE+  ++  +E+  L L VE      A + KK       + E +
Sbjct: 1109 KLTQESVADAAQDKQQLEEKLKKKDSELSQLSLRVEDEQLLGAQMQKK-------IKELQ 1161

Query: 1464 QKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIA 1523
             + EE   ELEA +     +  +  +     EE  ++LE     +   ++      ++ A
Sbjct: 1162 ARAEELEEELEAERAARARVEKQRAEAARELEELSERLEEAGGASAGQRE---GCRKREA 1218

Query: 1524 EGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIA 1583
            E G+   ELE+   + E     L+    E  A L  +   + R++ +L + KSE+     
Sbjct: 1219 ELGRLRRELEEAALRHEATVAALRRKQAEGAAELGEQVDSLQRVRQKLEKEKSELRM--- 1275

Query: 1584 EKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAA 1643
                E+D L  N    VE++        R++  A +L +  E  L+E +I++    R  A
Sbjct: 1276 ----EVDDLAAN----VETLT-------RAKASAEKLCRTYEDQLSEAKIKVEELQRQLA 1320

Query: 1644 EALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTER 1703
            +A       +G L+     L   L  +E L  QL+   R   L    +EELR  LE+  +
Sbjct: 1321 DA----STQRGRLQTESGELSRLLEEKECLISQLS---RGKALAAQSLEELRRQLEEESK 1373

Query: 1704 SRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQMQGEME--------DILQEAR 1755
            ++      +        LL  Q+      + +L+  +S+   E+         D +Q   
Sbjct: 1374 AKSALAHAVQALRHDCDLLREQHEEEAEAQAELQRLLSKANAEVAQWRSKYEADAIQRTE 1433

Query: 1756 NAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGK 1815
              EE  KK         E ++      + LE+ K  ++   +D+ L L+ A   A    K
Sbjct: 1434 ELEEAKKKLALRLQEAEEGVEAANAKCSSLEKAKLRLQTESEDVTLELERATSAAAALDK 1493

Query: 1816 KQI---QKLEARVR---ELEGEVESEQKRNA-----------------EAVKGLRKHERR 1852
            KQ    + LE R R   E++ E+E+ Q+ +                  EA++ L++  + 
Sbjct: 1494 KQRHLERALEERRRQEEEMQRELEAAQRESRGLGTELFRLRHGHEEALEALETLKRENKN 1553

Query: 1853 VKE----LTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHE 1908
            ++E    LT Q     K+I  L+     L+ +    +   EEAE        K  ++Q E
Sbjct: 1554 LQEEISDLTDQVSLSGKSIQELEKTKKALEGEKSEIQAALEEAEGALELEETKTLRIQLE 1613

Query: 1909 LEEAEERADIAESQVNKLRVKSREVHTKVI 1938
            L + +   D   ++ ++     R  H + +
Sbjct: 1614 LSQVKAEVDRKLAEKDEECANLRRNHQRAV 1643


>gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens]
          Length = 1946

 Score = 2318 bits (6008), Expect = 0.0
 Identities = 1157/1936 (59%), Positives = 1536/1936 (79%), Gaps = 12/1936 (0%)

Query: 6    ELAVFGEAAPFLRKSERERIEAQNRPFDAKTSVFVAEPKESFVKGTIQ-SREGGKVTVKT 64
            +L+  GEAA FLR+SE E +  Q    D K   ++ + + ++++  ++ S + G V V+T
Sbjct: 22   DLSDLGEAAAFLRRSEAELLLLQATALDGKKKCWIPDGENAYIEAEVKGSEDDGTVIVET 81

Query: 65   EGGATLTVKDDQVFPMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCV 124
              G +L++K+D++  MNPP+++ IEDMAM+THL+E +VL+ LK RY  WMIYTYSGLFCV
Sbjct: 82   ADGESLSIKEDKIQQMNPPEFEMIEDMAMLTHLNEASVLHTLKRRYGQWMIYTYSGLFCV 141

Query: 125  TVNPYKWLPVYKPEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAG 184
            T+NPYKWLPVY+ EV+ AY+GK+R EAPPHIF++++NA+Q ML +RENQSIL TGESGAG
Sbjct: 142  TINPYKWLPVYQKEVMAAYKGKRRSEAPPHIFAVANNAFQDMLHNRENQSILFTGESGAG 201

Query: 185  KTVNTKRVIQYFATIAVTGEKKKEEITSGKIQGTLEDQIISANPLLEAFGNAKTVRNDNS 244
            KTVN+K +IQYFATIA   E +K+       QG LEDQI+ AN +LEAFGNAKT+RNDNS
Sbjct: 202  KTVNSKHIIQYFATIAAMIESRKK-------QGALEDQIMQANTILEAFGNAKTLRNDNS 254

Query: 245  SRFGKFIRIHFGTTGKLASADIETYLLEKSRVVFQLKAERSYHIFYQITSNKKPELIEML 304
            SRFGKFIR+HFG  G L+S DI+ YLLEKSRV+FQ   ER+YHIFYQI S +K EL ++L
Sbjct: 255  SRFGKFIRMHFGARGMLSSVDIDIYLLEKSRVIFQQAGERNYHIFYQILSGQK-ELHDLL 313

Query: 305  LITTNPYDYPFVSQGEISVASIDDQEELMATDSAIDILGFTNEEKVSIYKLTGAVMHYGN 364
            L++ NP D+ F S G ++V S+DD EEL+AT+ A+DILGF  +EK   YKLTGA+MH+GN
Sbjct: 314  LVSANPSDFHFCSCGAVTVESLDDAEELLATEQAMDILGFLPDEKYGCYKLTGAIMHFGN 373

Query: 365  LKFKQKQREEQAEPDGTEVADKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTVEQVS 424
            +KFKQK REEQ E DGTE ADKAA+L  +NS++L+K L +PR+KVGNEYVT+GQT+EQV+
Sbjct: 374  MKFKQKPREEQLEADGTENADKAAFLMGINSSELVKCLIHPRIKVGNEYVTRGQTIEQVT 433

Query: 425  NAVGALAKAVYEKMFLWMVARINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFT 484
             AVGAL+K++YE+MF W+VARIN+ LD K  RQ+FIG+LDI GFEI ++NSLEQLCINFT
Sbjct: 434  CAVGALSKSMYERMFKWLVARINRALDAKLSRQFFIGILDITGFEILEYNSLEQLCINFT 493

Query: 485  NEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEECMFP 544
            NEKLQQFFN HMFVLEQEEYKKE IEW  I FG+DL ACI+LIEKPMGI SILEEECMFP
Sbjct: 494  NEKLQQFFNWHMFVLEQEEYKKESIEWVSIGFGLDLQACIDLIEKPMGILSILEEECMFP 553

Query: 545  KATDTSFKNKLYDQHLGKSANFQKPKVVKGKAEAHFALIHYAGVVDYNITGWLEKNKDPL 604
            KATD +FK KL+D H GKS + QKPK  K K EAHF L+HYAGVV YNI+GWLEKNKD L
Sbjct: 554  KATDLTFKTKLFDNHFGKSVHLQKPKPDKKKFEAHFELVHYAGVVPYNISGWLEKNKDLL 613

Query: 605  NETVVGLYQKSAMKTLAQLFSGAQTAEGEGAGGGAKKGGKKKGSSFQTVSALFRENLNKL 664
            NETVV ++QKS+ + LA LF    + +     G  K+   KKG+SFQTV++L +ENLNKL
Sbjct: 614  NETVVAVFQKSSNRLLASLFENYMSTDSAIPFGEKKR---KKGASFQTVASLHKENLNKL 670

Query: 665  MTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADF 724
            MTNL+ST PHFVRCI PN  K PG ++  LVL QLRCNGVLEG RICR+GFP+R+ YADF
Sbjct: 671  MTNLKSTAPHFVRCINPNVNKIPGILDPYLVLQQLRCNGVLEGTRICREGFPNRLQYADF 730

Query: 725  KQRYKVLNASAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRD 784
            KQRY +LN    P+ +F+ S+KA+E+LL S++IDHTQY+FG TKVFFKAG LG LE +RD
Sbjct: 731  KQRYCILNPRTFPKSKFVSSRKAAEELLGSLEIDHTQYRFGITKVFFKAGFLGQLEAIRD 790

Query: 785  DKLAQLITRTQARCRGFLARVEYQRMVERREAIFCIQYNIRSFMNVKHWPWMKLFFKIKP 844
            ++L+++ T  QAR +G L R+++Q+++E R+A+  IQ+NIR+FM VK+WPWM+LFFKIKP
Sbjct: 791  ERLSKVFTLFQARAQGKLMRIKFQKILEERDALILIQWNIRAFMAVKNWPWMRLFFKIKP 850

Query: 845  LLKSAETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGL 904
            L+KS+E  +E+A +KEE  +++  L KSE +R+EL+ K V+L +EKNDL LQ+QAE E L
Sbjct: 851  LVKSSEVGEEVAGLKEECAQLQKALEKSEFQREELKAKQVSLTQEKNDLILQLQAEQETL 910

Query: 905  ADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLE 964
            A+ EE+C+ LIK+KIQLEA++KE++ER E+EEEIN+ELTA+ RKLEDEC ELKK+IDDLE
Sbjct: 911  ANVEEQCEWLIKSKIQLEARVKELSERVEEEEEINSELTARGRKLEDECFELKKEIDDLE 970

Query: 965  LTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVN 1024
              L K EKEK  TE+KVKNLTEE+  L+E I+KL +  K +QEAHQQTLDDL  EE+K++
Sbjct: 971  TMLVKSEKEKRTTEHKVKNLTEEVEFLNEDISKLNRAAKVVQEAHQQTLDDLHMEEEKLS 1030

Query: 1025 TLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDE 1084
            +L+KA +KLEQQVD+LEG+LEQE+K RM+ ER   KLEG+LKL +ES+ ++E+ ++ L E
Sbjct: 1031 SLSKANLKLEQQVDELEGALEQERKARMNCERELHKLEGNLKLNRESMENLESSQRHLAE 1090

Query: 1085 KLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSD 1144
            +L+KKE E+S + SK+E+E+ L  QLQK +KELQ +I++L+E++EAER +RAK E++R+D
Sbjct: 1091 ELRKKELELSQMNSKVENEKGLVAQLQKTVKELQTQIKDLKEKLEAERTTRAKMERERAD 1150

Query: 1145 LSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHAD 1204
            L+++L +++ERLEE GG++ AQ+E+ KK+E +FQK+ RD+EEATL  E T+A+L+K+HAD
Sbjct: 1151 LTQDLADLNERLEEVGGSSLAQLEITKKQETKFQKLHRDMEEATLHFETTSASLKKRHAD 1210

Query: 1205 SVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSE 1264
            S+AEL  Q++NLQ+VKQKLEK+KS++++E+DDL + VE +++AK N EK+C   E++L E
Sbjct: 1211 SLAELEGQVENLQQVKQKLEKDKSDLQLEVDDLLTRVEQMTRAKANAEKLCTLYEERLHE 1270

Query: 1265 LKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQ 1324
              +K ++  +L NDL AQ+ +L +ESGEF R+L+EKEAL++QLSR K  FT+QIE+L+ Q
Sbjct: 1271 ATAKLDKVTQLANDLAAQKTKLWSESGEFLRRLEEKEALINQLSREKSNFTRQIEDLRGQ 1330

Query: 1325 LEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETD 1384
            LE+E K+++ALAHALQ ++ DCDLLREQYEEEQE KAEL R LSK N E+ QWR KYE +
Sbjct: 1331 LEKETKSQSALAHALQKAQRDCDLLREQYEEEQEVKAELHRTLSKVNAEMVQWRMKYENN 1390

Query: 1385 AIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAA 1444
             IQRTE+LE+AKK+LA RLQ A E +   NA+ ASLE+ + +LQ E+ D + D+ +  +A
Sbjct: 1391 VIQRTEDLEDAKKELAIRLQEAAEAMGVANARNASLERARHQLQLELGDALSDLGKVRSA 1450

Query: 1445 CAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETL 1504
             A LD+KQ    K LA+WKQK EE+ A L+ASQKE ++L TEL K+KN YEES+   ETL
Sbjct: 1451 AARLDQKQLQSGKALADWKQKHEESQALLDASQKEVQALSTELLKLKNTYEESIVGQETL 1510

Query: 1505 KRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKI 1564
            +RENKNLQ+EIS+LT Q+ EG K + E+EK+KK +E+EK E+Q  LEE E +LE  E KI
Sbjct: 1511 RRENKNLQEEISNLTNQVREGTKNLTEMEKVKKLIEEEKTEVQVTLEETEGALERNESKI 1570

Query: 1565 LRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKM 1624
            L  QLEL + K+E++RK++EKDEEI+  +R     ++S+QS+LD+E +SR +  RLKKKM
Sbjct: 1571 LHFQLELLEAKAELERKLSEKDEEIENFRRKQQCTIDSLQSSLDSEAKSRIEVTRLKKKM 1630

Query: 1625 EGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRA 1684
            E DLNEME+QL+ ANR  +EA ++    Q  +KD Q+ LDD+ +   DLKEQ+A+ ERR 
Sbjct: 1631 EEDLNEMELQLSCANRQVSEATKSLGQLQIQIKDLQMQLDDSTQLNSDLKEQVAVAERRN 1690

Query: 1685 NLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQMQ 1744
            +LLQ+E+E+LR+  EQTER R+++E+ELL+A+ER+ L +TQNTSL++ KKKLE D+++MQ
Sbjct: 1691 SLLQSELEDLRSLQEQTERGRRLSEEELLEATERINLFYTQNTSLLSQKKKLEADVARMQ 1750

Query: 1745 GEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLD 1804
             E E+++QE +NAEEKAKKA  +AA ++EELKK+QDT AHLER ++NMEQT+ DLQ RL 
Sbjct: 1751 KEAEEVVQECQNAEEKAKKAAIEAANLSEELKKKQDTIAHLERTRENMEQTITDLQKRLA 1810

Query: 1805 EAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDR 1864
            EAEQ+AL G +KQIQKLE+RVRELEGE+E E +R+AEA +G R+ ER +KELTYQ EED+
Sbjct: 1811 EAEQMALMGSRKQIQKLESRVRELEGELEGEIRRSAEAQRGARRLERCIKELTYQAEEDK 1870

Query: 1865 KNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAESQVN 1924
            KN+ R+Q  +DKLQ KV++YK+Q E AE Q+N  L+K++K QHEL E +ERA++AESQVN
Sbjct: 1871 KNLSRMQTQMDKLQLKVQNYKQQVEVAETQANQYLSKYKKQQHELNEVKERAEVAESQVN 1930

Query: 1925 KLRVKSREVHTKVISE 1940
            KL++K+RE   KV  E
Sbjct: 1931 KLKIKAREFGKKVQEE 1946


>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
            sapiens]
          Length = 1972

 Score = 1423 bits (3683), Expect = 0.0
 Identities = 779/1908 (40%), Positives = 1181/1908 (61%), Gaps = 20/1908 (1%)

Query: 34   AKTSVFVAEPKESFVKGTIQSREGGKVTVK-TEGGATLTVKDDQVFPMNPPKYDKIEDMA 92
            AK  V+V   K+ F   +I+  +G +V V+  E G  +TV  D +  MNPPK+ K+EDMA
Sbjct: 32   AKRLVWVPSEKQGFEAASIKEEKGDEVVVELVENGKKVTVGKDDIQKMNPPKFSKVEDMA 91

Query: 93   MMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYKPEVVTAYRGKKRQEAP 152
             +T L+E +VL+NL+ERY + +IYTYSGLFCV VNPYK LP+Y  ++V  Y+GKKR E P
Sbjct: 92   ELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKRHEMP 151

Query: 153  PHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKEEITS 212
            PHI++I+D AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY A +A + + KK+    
Sbjct: 152  PHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKDT--- 208

Query: 213  GKIQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLE 272
              I G LE Q++ ANP+LEAFGNAKTV+NDNSSRFGKFIRI+F  TG +  A+IETYLLE
Sbjct: 209  -SITGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLE 267

Query: 273  KSRVVFQLKAERSYHIFYQITSNKKPELIEMLLITTNPYDYPFVSQGEISVASIDDQEEL 332
            KSR + Q + ER++HIFY + +  K ++   LL+     +Y F+S G + + +  D E  
Sbjct: 268  KSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLE-GFNNYTFLSNGFVPIPAAQDDEMF 326

Query: 333  MATDSAIDILGFTNEEKVSIYKLTGAVMHYGNLKFKQKQREEQAEPDGTEVADKAAYLQS 392
              T  A+ I+GF+ EE++SI K+  +V+  GN+ FK+++  +QA       A K  +L  
Sbjct: 327  QETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKVCHLMG 386

Query: 393  LNSADLLKALCYPRVKVGNEYVTKGQTVEQVSNAVGALAKAVYEKMFLWMVARINQQLD- 451
            +N  D  +++  PR+KVG + V K QT EQ   AV ALAKA YE++F W++ R+N+ LD 
Sbjct: 387  INVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRVNKALDK 446

Query: 452  TKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEW 511
            T +    F+G+LDIAGFEIF+ NS EQLCIN+TNEKLQQ FNH MF+LEQEEY++EGIEW
Sbjct: 447  THRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEW 506

Query: 512  TFIDFGMDLAACIELIEKPM---GIFSILEEECMFPKATDTSFKNKLYDQHLGKSANFQK 568
             FIDFG+DL  CIELIE+P    G+ ++L+EEC FPKATD SF  KL  +  G    FQK
Sbjct: 507  NFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQ-GSHPKFQK 565

Query: 569  PKVVKGKAEAHFALIHYAGVVDYNITGWLEKNKDPLNETVVGLYQKSAMKTLAQLFSGAQ 628
            PK +K K E  F++IHYAG VDYN + WL KN DPLN+ V  L   S+ K +A L+    
Sbjct: 566  PKQLKDKTE--FSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLWKDVD 623

Query: 629  TAEG-----EGAGGGAKKGGKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPNE 683
               G     +          K K   F+TV  L++E L KLMT LR+T P+FVRCIIPN 
Sbjct: 624  RIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCIIPNH 683

Query: 684  TKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQFID 743
             K  G ++  LVL QLRCNGVLEGIRICR+GFP+RI++ +F+QRY++L A+AIP+G F+D
Sbjct: 684  EKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKG-FMD 742

Query: 744  SKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDDKLAQLITRTQARCRGFLA 803
             K+A   ++ ++++D   Y+ G +K+FF+ G+L  LEE RD K+  +I   QA CRG+LA
Sbjct: 743  GKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRGYLA 802

Query: 804  RVEYQRMVERREAIFCIQYNIRSFMNVKHWPWMKLFFKIKPLLKSAETEKEMATMKEEFQ 863
            R  + +  ++  A+  IQ N  +++ +++W W +LF K+KPLL+    E+EM   ++E Q
Sbjct: 803  RKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKEDELQ 862

Query: 864  KIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCDQLIKTKIQLEA 923
            K K+   K+E + KELE+K   L +EKN LQ Q+QAE E  A+AEE   +L   K +LE 
Sbjct: 863  KTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEE 922

Query: 924  KIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKN 983
             + E+  R E+EE+   +L A+++K+  +  +L++ +++ E    K++ EK   E K+K 
Sbjct: 923  ILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKK 982

Query: 984  LTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGS 1043
            L +E+  +D+   KL+KE+K L+E       +L  EE+K   LTK K K E  + +LE  
Sbjct: 983  LEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVR 1042

Query: 1044 LEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDE 1103
            L++E+K R +LE+ KRKLEGD     E I D++ +  +L  +L KKE E+    ++++DE
Sbjct: 1043 LKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDE 1102

Query: 1104 QALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGAT 1163
             A      KKI+EL+  I +L+E++++ERA+R KAEKQ+ DL  ELE +   LE+   +T
Sbjct: 1103 IAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDST 1162

Query: 1164 SAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKL 1223
            + Q E+  KRE E   +++ L+E T  HEA    +R+KHA +V EL EQ++  +R K  L
Sbjct: 1163 ATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANL 1222

Query: 1224 EKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQR 1283
            +K K  ++ E  DLA  +  + +AK  +E   + LE Q+ EL+SK  + +R   +L  + 
Sbjct: 1223 DKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKV 1282

Query: 1284 GRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSR 1343
             +LQ E    +  L+E E    +L++   + + Q+++ +  L+EE + K  ++  L+   
Sbjct: 1283 HKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLE 1342

Query: 1344 HDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRL 1403
             + + L++Q +EE E+K  L+R +S  N +++  + K + D     E LEE KK+  + +
Sbjct: 1343 EERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQ-DFASTVEALEEGKKRFQKEI 1401

Query: 1404 QAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWK 1463
            +   +  E   A    LEKTK RLQ E++DL++D++      + L+KKQR FD++LAE K
Sbjct: 1402 ENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEK 1461

Query: 1464 QKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIA 1523
                +   E + ++ EAR   T+   +  A EE+L+  E L+R NK L+ E+ DL     
Sbjct: 1462 NISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKD 1521

Query: 1524 EGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIA 1583
            + GK +HELEK K+ +E +  E++  LEE E  L+  E   LR+++ +  +K + +R + 
Sbjct: 1522 DVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQ 1581

Query: 1584 EKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAA 1643
             +DE+ ++ +R   R +   ++ L+ E + R  A   KKK+EGDL ++E+Q + A +   
Sbjct: 1582 ARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGRE 1641

Query: 1644 EALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTER 1703
            EA++  R  Q  +KD Q  L+DA  S++++       E++A  L+A++ +L+  L   ER
Sbjct: 1642 EAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAER 1701

Query: 1704 SRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKK 1763
            +RK A+ E  + +E +    +   +L + K++LE  I+Q++ E+E+         ++ +K
Sbjct: 1702 ARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRK 1761

Query: 1764 AITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEA 1823
            A   A  ++ EL  E+ T+   E  ++ +E+  K+L+ +L E E       K  I  LEA
Sbjct: 1762 ATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEA 1821

Query: 1824 RVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKS 1883
            ++ +LE +VE E +    A K L++ ++++KE+  Q E++RK   + ++  +K  A+VK 
Sbjct: 1822 KIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQ 1881

Query: 1884 YKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAESQVNKLRVKSR 1931
             KRQ EEAEE+S    A  RKLQ EL+EA E  +    +VN L+ K R
Sbjct: 1882 LKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLR 1929



 Score =  216 bits (549), Expect = 2e-55
 Identities = 189/902 (20%), Positives = 433/902 (48%), Gaps = 53/902 (5%)

Query: 1083 DEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQR 1142
            +E+++ KE E+   + + +  +    +L++K  +L      L+E+++AE    A+AE+ R
Sbjct: 851  EEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMR 910

Query: 1143 SDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRR---DLEEATLQHEATAATLR 1199
              L+ + +E+ E L E       + +  ++ +AE +KM +   DLEE   + EA    L+
Sbjct: 911  VRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQ 970

Query: 1200 KKHADSVAE---LGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCR 1256
             +   + A+   L ++I  +     KL KE+  ++  I DL +N+    +   NL K+  
Sbjct: 971  LEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKN 1030

Query: 1257 TLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQ 1316
              E  +SEL+ + +++++   +L   + +L+ ++ +F  Q+ + +A +++L        +
Sbjct: 1031 KHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEE 1090

Query: 1317 QIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQ 1376
            +++    +L++EI  KN     ++        L+E  + E+ ++ + ++       E+  
Sbjct: 1091 ELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEA 1150

Query: 1377 WRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHV-EAVNAKCASLEKTKQRLQNEVEDLM 1435
             +T+ E D +  T   +E + K  Q +   ++ + E   +  A +++ +Q+    VE+L 
Sbjct: 1151 LKTELE-DTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELT 1209

Query: 1436 LDVERTNAACAALDKKQRNFDK----------ILAEWKQKCEETHAELEASQKEARS--- 1482
              +E+   A A LDK ++  +K          +L + KQ+ E    +LEA  +E +S   
Sbjct: 1210 EQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCS 1269

Query: 1483 --------LGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEK 1534
                    L  ++ K++N  E     L   + +   L ++++ L+ Q+ +  + + E  +
Sbjct: 1270 DGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETR 1329

Query: 1535 IK-------KQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDE 1587
             K       +Q+E+E+  LQ  L+E   + ++ E  I  + ++L+  K ++ +  A   E
Sbjct: 1330 QKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKL-QDFASTVE 1388

Query: 1588 EIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALR 1647
             +++ K+   + +E++    + +  + +   + K +++ +L+++ + L++  ++ +   +
Sbjct: 1389 ALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEK 1448

Query: 1648 NYRNTQGILKD----TQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTER 1703
              R    +L +    +  + D+  R++ + +E+    E +A  L   +EE     E+ ER
Sbjct: 1449 KQRKFDQLLAEEKNISSKYADERDRAEAEAREK----ETKALSLARALEEALEAKEELER 1504

Query: 1704 SRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEE-KAK 1762
            + K+ + E+ D       +      L  +K+ LET + +M+ ++E++  E +  E+ K +
Sbjct: 1505 TNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLR 1564

Query: 1763 KAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRL-DEAEQLALKGGKKQIQKL 1821
              +   A+  +  +  Q      E  ++ +++ + + +  L DE +Q AL    K+  KL
Sbjct: 1565 LEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKK--KL 1622

Query: 1822 EARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKV 1881
            E  +++LE + +S  K   EA+K LRK + ++K+   + E+ R +   +     + + K 
Sbjct: 1623 EGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKA 1682

Query: 1882 KSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAESQV--NKLRVKSREVHTKVIS 1939
            KS   +A+  + Q +   A+  + Q +LE+ E   ++A S    N L+ + R +  ++  
Sbjct: 1683 KSL--EADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQ 1740

Query: 1940 EE 1941
             E
Sbjct: 1741 LE 1742



 Score = 96.3 bits (238), Expect = 3e-19
 Identities = 78/366 (21%), Positives = 165/366 (45%), Gaps = 44/366 (12%)

Query: 847  KSAETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLAD 906
            K  + ++++   + E +  + + A + A +K+LE  +        DL+LQ  +  +G  +
Sbjct: 1590 KRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDL-------KDLELQADSAIKGREE 1642

Query: 907  AEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELT 966
            A       IK   +L+A++K+     ED      E+ A  ++ E +   L+ D+  L+  
Sbjct: 1643 A-------IKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQED 1695

Query: 967  LAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTL 1026
            LA  E+ +   + + + L EE+A        L  EK+ L+    Q  ++L+ E+  +  +
Sbjct: 1696 LAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAM 1755

Query: 1027 TKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENE-------- 1078
            +    K  QQ + L   L  E+      E A+++LE   K  +  + ++E          
Sbjct: 1756 SDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKST 1815

Query: 1079 -----------KQQLDEK----------LKKKEFEISNLQSKIEDEQALGIQLQKKIKEL 1117
                       ++Q++++          LK+K+ ++  +  ++EDE+ +  Q +++ ++ 
Sbjct: 1816 IAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKG 1875

Query: 1118 QARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSA-QIEMNKKREAE 1176
             AR+++L+ ++E       +    R  L REL+E +E  E  G   +A + ++ +  E  
Sbjct: 1876 NARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLRRGNETS 1935

Query: 1177 FQKMRR 1182
            F   RR
Sbjct: 1936 FVPSRR 1941



 Score = 75.5 bits (184), Expect = 5e-13
 Identities = 59/271 (21%), Positives = 119/271 (43%), Gaps = 8/271 (2%)

Query: 1668 RSQEDLK---EQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHT 1724
            R +E+++   ++L   + R    + E++EL     Q    + + +++L   +E       
Sbjct: 849  RQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEE 908

Query: 1725 QNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAH 1784
                L   K++LE  + +M+  +E+     +  + + KK       + E+L++E+     
Sbjct: 909  MRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQK 968

Query: 1785 LERMKKNMEQTVKDLQLRLDEAEQLALKGGK--KQIQKLEARVRELEGEVESEQKRNAEA 1842
            L+  K   E  +K L+   DE   +  +  K  K+ + LE R+ +L   +  E+++    
Sbjct: 969  LQLEKVTAEAKIKKLE---DEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNL 1025

Query: 1843 VKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKF 1902
             K   KHE  + EL  + +++ K+   L+ L  KL+     +  Q  + + Q      + 
Sbjct: 1026 TKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQL 1085

Query: 1903 RKLQHELEEAEERADIAESQVNKLRVKSREV 1933
             K + EL+ A  R D   +Q N    K RE+
Sbjct: 1086 AKKEEELQAALARLDDEIAQKNNALKKIREL 1116


>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
            sapiens]
          Length = 1979

 Score = 1423 bits (3683), Expect = 0.0
 Identities = 781/1911 (40%), Positives = 1183/1911 (61%), Gaps = 19/1911 (0%)

Query: 34   AKTSVFVAEPKESFVKGTIQSREGGKVTVK-TEGGATLTVKDDQVFPMNPPKYDKIEDMA 92
            AK  V+V   K+ F   +I+  +G +V V+  E G  +TV  D +  MNPPK+ K+EDMA
Sbjct: 32   AKRLVWVPSEKQGFEAASIKEEKGDEVVVELVENGKKVTVGKDDIQKMNPPKFSKVEDMA 91

Query: 93   MMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYKPEVVTAYRGKKRQEAP 152
             +T L+E +VL+NL+ERY + +IYTYSGLFCV VNPYK LP+Y  ++V  Y+GKKR E P
Sbjct: 92   ELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKRHEMP 151

Query: 153  PHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKE-EIT 211
            PHI++I+D AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY A +A + + KK+  IT
Sbjct: 152  PHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKDTSIT 211

Query: 212  SGK--IQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETY 269
             G     G LE Q++ ANP+LEAFGNAKTV+NDNSSRFGKFIRI+F  TG +  A+IETY
Sbjct: 212  QGPSFAYGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETY 271

Query: 270  LLEKSRVVFQLKAERSYHIFYQITSNKKPELIEMLLITTNPYDYPFVSQGEISVASIDDQ 329
            LLEKSR + Q + ER++HIFY + +  K ++   LL+     +Y F+S G + + +  D 
Sbjct: 272  LLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLE-GFNNYTFLSNGFVPIPAAQDD 330

Query: 330  EELMATDSAIDILGFTNEEKVSIYKLTGAVMHYGNLKFKQKQREEQAEPDGTEVADKAAY 389
            E    T  A+ I+GF+ EE++SI K+  +V+  GN+ FK+++  +QA       A K  +
Sbjct: 331  EMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKVCH 390

Query: 390  LQSLNSADLLKALCYPRVKVGNEYVTKGQTVEQVSNAVGALAKAVYEKMFLWMVARINQQ 449
            L  +N  D  +++  PR+KVG + V K QT EQ   AV ALAKA YE++F W++ R+N+ 
Sbjct: 391  LMGINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRVNKA 450

Query: 450  LD-TKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEG 508
            LD T +    F+G+LDIAGFEIF+ NS EQLCIN+TNEKLQQ FNH MF+LEQEEY++EG
Sbjct: 451  LDKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREG 510

Query: 509  IEWTFIDFGMDLAACIELIEKPM---GIFSILEEECMFPKATDTSFKNKLYDQHLGKSAN 565
            IEW FIDFG+DL  CIELIE+P    G+ ++L+EEC FPKATD SF  KL  +  G    
Sbjct: 511  IEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQ-GSHPK 569

Query: 566  FQKPKVVKGKAEAHFALIHYAGVVDYNITGWLEKNKDPLNETVVGLYQKSAMKTLAQLFS 625
            FQKPK +K K E  F++IHYAG VDYN + WL KN DPLN+ V  L   S+ K +A L+ 
Sbjct: 570  FQKPKQLKDKTE--FSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLWK 627

Query: 626  GAQTAEG-----EGAGGGAKKGGKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCII 680
                  G     +          K K   F+TV  L++E L KLMT LR+T P+FVRCII
Sbjct: 628  DVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCII 687

Query: 681  PNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQ 740
            PN  K  G ++  LVL QLRCNGVLEGIRICR+GFP+RI++ +F+QRY++L A+AIP+G 
Sbjct: 688  PNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKG- 746

Query: 741  FIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDDKLAQLITRTQARCRG 800
            F+D K+A   ++ ++++D   Y+ G +K+FF+ G+L  LEE RD K+  +I   QA CRG
Sbjct: 747  FMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRG 806

Query: 801  FLARVEYQRMVERREAIFCIQYNIRSFMNVKHWPWMKLFFKIKPLLKSAETEKEMATMKE 860
            +LAR  + +  ++  A+  IQ N  +++ +++W W +LF K+KPLL+    E+EM   ++
Sbjct: 807  YLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKED 866

Query: 861  EFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCDQLIKTKIQ 920
            E QK K+   K+E + KELE+K   L +EKN LQ Q+QAE E  A+AEE   +L   K +
Sbjct: 867  ELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQE 926

Query: 921  LEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENK 980
            LE  + E+  R E+EE+   +L A+++K+  +  +L++ +++ E    K++ EK   E K
Sbjct: 927  LEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAK 986

Query: 981  VKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDL 1040
            +K L +E+  +D+   KL+KE+K L+E       +L  EE+K   LTK K K E  + +L
Sbjct: 987  IKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISEL 1046

Query: 1041 EGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKI 1100
            E  L++E+K R +LE+ KRKLEGD     E I D++ +  +L  +L KKE E+    +++
Sbjct: 1047 EVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARL 1106

Query: 1101 EDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAG 1160
            +DE A      KKI+EL+  I +L+E++++ERA+R KAEKQ+ DL  ELE +   LE+  
Sbjct: 1107 DDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTL 1166

Query: 1161 GATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVK 1220
             +T+ Q E+  KRE E   +++ L+E T  HEA    +R+KHA +V EL EQ++  +R K
Sbjct: 1167 DSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAK 1226

Query: 1221 QKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLT 1280
              L+K K  ++ E  DLA  +  + +AK  +E   + LE Q+ EL+SK  + +R   +L 
Sbjct: 1227 ANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELN 1286

Query: 1281 AQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQ 1340
             +  +LQ E    +  L+E E    +L++   + + Q+++ +  L+EE + K  ++  L+
Sbjct: 1287 DKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLR 1346

Query: 1341 SSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLA 1400
                + + L++Q +EE E+K  L+R +S  N +++  + K + D     E LEE KK+  
Sbjct: 1347 QLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQ-DFASTVEALEEGKKRFQ 1405

Query: 1401 QRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILA 1460
            + ++   +  E   A    LEKTK RLQ E++DL++D++      + L+KKQR FD++LA
Sbjct: 1406 KEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLA 1465

Query: 1461 EWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTE 1520
            E K    +   E + ++ EAR   T+   +  A EE+L+  E L+R NK L+ E+ DL  
Sbjct: 1466 EEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVS 1525

Query: 1521 QIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDR 1580
               + GK +HELEK K+ +E +  E++  LEE E  L+  E   LR+++ +  +K + +R
Sbjct: 1526 SKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFER 1585

Query: 1581 KIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANR 1640
             +  +DE+ ++ +R   R +   ++ L+ E + R  A   KKK+EGDL ++E+Q + A +
Sbjct: 1586 DLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIK 1645

Query: 1641 MAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQ 1700
               EA++  R  Q  +KD Q  L+DA  S++++       E++A  L+A++ +L+  L  
Sbjct: 1646 GREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAA 1705

Query: 1701 TERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEK 1760
             ER+RK A+ E  + +E +    +   +L + K++LE  I+Q++ E+E+         ++
Sbjct: 1706 AERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDR 1765

Query: 1761 AKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQK 1820
             +KA   A  ++ EL  E+ T+   E  ++ +E+  K+L+ +L E E       K  I  
Sbjct: 1766 VRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAA 1825

Query: 1821 LEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAK 1880
            LEA++ +LE +VE E +    A K L++ ++++KE+  Q E++RK   + ++  +K  A+
Sbjct: 1826 LEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNAR 1885

Query: 1881 VKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAESQVNKLRVKSR 1931
            VK  KRQ EEAEE+S    A  RKLQ EL+EA E  +    +VN L+ K R
Sbjct: 1886 VKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLR 1936



 Score =  216 bits (549), Expect = 2e-55
 Identities = 189/902 (20%), Positives = 433/902 (48%), Gaps = 53/902 (5%)

Query: 1083 DEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQR 1142
            +E+++ KE E+   + + +  +    +L++K  +L      L+E+++AE    A+AE+ R
Sbjct: 858  EEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMR 917

Query: 1143 SDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRR---DLEEATLQHEATAATLR 1199
              L+ + +E+ E L E       + +  ++ +AE +KM +   DLEE   + EA    L+
Sbjct: 918  VRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQ 977

Query: 1200 KKHADSVAE---LGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCR 1256
             +   + A+   L ++I  +     KL KE+  ++  I DL +N+    +   NL K+  
Sbjct: 978  LEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKN 1037

Query: 1257 TLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQ 1316
              E  +SEL+ + +++++   +L   + +L+ ++ +F  Q+ + +A +++L        +
Sbjct: 1038 KHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEE 1097

Query: 1317 QIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQ 1376
            +++    +L++EI  KN     ++        L+E  + E+ ++ + ++       E+  
Sbjct: 1098 ELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEA 1157

Query: 1377 WRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHV-EAVNAKCASLEKTKQRLQNEVEDLM 1435
             +T+ E D +  T   +E + K  Q +   ++ + E   +  A +++ +Q+    VE+L 
Sbjct: 1158 LKTELE-DTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELT 1216

Query: 1436 LDVERTNAACAALDKKQRNFDK----------ILAEWKQKCEETHAELEASQKEARS--- 1482
              +E+   A A LDK ++  +K          +L + KQ+ E    +LEA  +E +S   
Sbjct: 1217 EQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCS 1276

Query: 1483 --------LGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEK 1534
                    L  ++ K++N  E     L   + +   L ++++ L+ Q+ +  + + E  +
Sbjct: 1277 DGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETR 1336

Query: 1535 IK-------KQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDE 1587
             K       +Q+E+E+  LQ  L+E   + ++ E  I  + ++L+  K ++ +  A   E
Sbjct: 1337 QKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKL-QDFASTVE 1395

Query: 1588 EIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALR 1647
             +++ K+   + +E++    + +  + +   + K +++ +L+++ + L++  ++ +   +
Sbjct: 1396 ALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEK 1455

Query: 1648 NYRNTQGILKD----TQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTER 1703
              R    +L +    +  + D+  R++ + +E+    E +A  L   +EE     E+ ER
Sbjct: 1456 KQRKFDQLLAEEKNISSKYADERDRAEAEAREK----ETKALSLARALEEALEAKEELER 1511

Query: 1704 SRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEE-KAK 1762
            + K+ + E+ D       +      L  +K+ LET + +M+ ++E++  E +  E+ K +
Sbjct: 1512 TNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLR 1571

Query: 1763 KAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRL-DEAEQLALKGGKKQIQKL 1821
              +   A+  +  +  Q      E  ++ +++ + + +  L DE +Q AL    K+  KL
Sbjct: 1572 LEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKK--KL 1629

Query: 1822 EARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKV 1881
            E  +++LE + +S  K   EA+K LRK + ++K+   + E+ R +   +     + + K 
Sbjct: 1630 EGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKA 1689

Query: 1882 KSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAESQV--NKLRVKSREVHTKVIS 1939
            KS   +A+  + Q +   A+  + Q +LE+ E   ++A S    N L+ + R +  ++  
Sbjct: 1690 KSL--EADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQ 1747

Query: 1940 EE 1941
             E
Sbjct: 1748 LE 1749



 Score = 96.3 bits (238), Expect = 3e-19
 Identities = 78/366 (21%), Positives = 165/366 (45%), Gaps = 44/366 (12%)

Query: 847  KSAETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLAD 906
            K  + ++++   + E +  + + A + A +K+LE  +        DL+LQ  +  +G  +
Sbjct: 1597 KRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDL-------KDLELQADSAIKGREE 1649

Query: 907  AEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELT 966
            A       IK   +L+A++K+     ED      E+ A  ++ E +   L+ D+  L+  
Sbjct: 1650 A-------IKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQED 1702

Query: 967  LAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTL 1026
            LA  E+ +   + + + L EE+A        L  EK+ L+    Q  ++L+ E+  +  +
Sbjct: 1703 LAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAM 1762

Query: 1027 TKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENE-------- 1078
            +    K  QQ + L   L  E+      E A+++LE   K  +  + ++E          
Sbjct: 1763 SDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKST 1822

Query: 1079 -----------KQQLDEK----------LKKKEFEISNLQSKIEDEQALGIQLQKKIKEL 1117
                       ++Q++++          LK+K+ ++  +  ++EDE+ +  Q +++ ++ 
Sbjct: 1823 IAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKG 1882

Query: 1118 QARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSA-QIEMNKKREAE 1176
             AR+++L+ ++E       +    R  L REL+E +E  E  G   +A + ++ +  E  
Sbjct: 1883 NARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLRRGNETS 1942

Query: 1177 FQKMRR 1182
            F   RR
Sbjct: 1943 FVPSRR 1948



 Score = 75.5 bits (184), Expect = 5e-13
 Identities = 59/271 (21%), Positives = 119/271 (43%), Gaps = 8/271 (2%)

Query: 1668 RSQEDLK---EQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHT 1724
            R +E+++   ++L   + R    + E++EL     Q    + + +++L   +E       
Sbjct: 856  RQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEE 915

Query: 1725 QNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAH 1784
                L   K++LE  + +M+  +E+     +  + + KK       + E+L++E+     
Sbjct: 916  MRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQK 975

Query: 1785 LERMKKNMEQTVKDLQLRLDEAEQLALKGGK--KQIQKLEARVRELEGEVESEQKRNAEA 1842
            L+  K   E  +K L+   DE   +  +  K  K+ + LE R+ +L   +  E+++    
Sbjct: 976  LQLEKVTAEAKIKKLE---DEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNL 1032

Query: 1843 VKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKF 1902
             K   KHE  + EL  + +++ K+   L+ L  KL+     +  Q  + + Q      + 
Sbjct: 1033 TKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQL 1092

Query: 1903 RKLQHELEEAEERADIAESQVNKLRVKSREV 1933
             K + EL+ A  R D   +Q N    K RE+
Sbjct: 1093 AKKEEELQAALARLDDEIAQKNNALKKIREL 1123


>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
            sapiens]
          Length = 1945

 Score = 1423 bits (3683), Expect = 0.0
 Identities = 781/1911 (40%), Positives = 1183/1911 (61%), Gaps = 19/1911 (0%)

Query: 34   AKTSVFVAEPKESFVKGTIQSREGGKVTVK-TEGGATLTVKDDQVFPMNPPKYDKIEDMA 92
            AK  V+V   K+ F   +I+  +G +V V+  E G  +TV  D +  MNPPK+ K+EDMA
Sbjct: 32   AKRLVWVPSEKQGFEAASIKEEKGDEVVVELVENGKKVTVGKDDIQKMNPPKFSKVEDMA 91

Query: 93   MMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYKPEVVTAYRGKKRQEAP 152
             +T L+E +VL+NL+ERY + +IYTYSGLFCV VNPYK LP+Y  ++V  Y+GKKR E P
Sbjct: 92   ELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKRHEMP 151

Query: 153  PHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKE-EIT 211
            PHI++I+D AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY A +A + + KK+  IT
Sbjct: 152  PHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKDTSIT 211

Query: 212  SGK--IQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETY 269
             G     G LE Q++ ANP+LEAFGNAKTV+NDNSSRFGKFIRI+F  TG +  A+IETY
Sbjct: 212  QGPSFAYGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETY 271

Query: 270  LLEKSRVVFQLKAERSYHIFYQITSNKKPELIEMLLITTNPYDYPFVSQGEISVASIDDQ 329
            LLEKSR + Q + ER++HIFY + +  K ++   LL+     +Y F+S G + + +  D 
Sbjct: 272  LLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLE-GFNNYTFLSNGFVPIPAAQDD 330

Query: 330  EELMATDSAIDILGFTNEEKVSIYKLTGAVMHYGNLKFKQKQREEQAEPDGTEVADKAAY 389
            E    T  A+ I+GF+ EE++SI K+  +V+  GN+ FK+++  +QA       A K  +
Sbjct: 331  EMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKVCH 390

Query: 390  LQSLNSADLLKALCYPRVKVGNEYVTKGQTVEQVSNAVGALAKAVYEKMFLWMVARINQQ 449
            L  +N  D  +++  PR+KVG + V K QT EQ   AV ALAKA YE++F W++ R+N+ 
Sbjct: 391  LMGINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRVNKA 450

Query: 450  LD-TKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEG 508
            LD T +    F+G+LDIAGFEIF+ NS EQLCIN+TNEKLQQ FNH MF+LEQEEY++EG
Sbjct: 451  LDKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREG 510

Query: 509  IEWTFIDFGMDLAACIELIEKPM---GIFSILEEECMFPKATDTSFKNKLYDQHLGKSAN 565
            IEW FIDFG+DL  CIELIE+P    G+ ++L+EEC FPKATD SF  KL  +  G    
Sbjct: 511  IEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQ-GSHPK 569

Query: 566  FQKPKVVKGKAEAHFALIHYAGVVDYNITGWLEKNKDPLNETVVGLYQKSAMKTLAQLFS 625
            FQKPK +K K E  F++IHYAG VDYN + WL KN DPLN+ V  L   S+ K +A L+ 
Sbjct: 570  FQKPKQLKDKTE--FSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLWK 627

Query: 626  GAQTAEG-----EGAGGGAKKGGKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCII 680
                  G     +          K K   F+TV  L++E L KLMT LR+T P+FVRCII
Sbjct: 628  DVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCII 687

Query: 681  PNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQ 740
            PN  K  G ++  LVL QLRCNGVLEGIRICR+GFP+RI++ +F+QRY++L A+AIP+G 
Sbjct: 688  PNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKG- 746

Query: 741  FIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDDKLAQLITRTQARCRG 800
            F+D K+A   ++ ++++D   Y+ G +K+FF+ G+L  LEE RD K+  +I   QA CRG
Sbjct: 747  FMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRG 806

Query: 801  FLARVEYQRMVERREAIFCIQYNIRSFMNVKHWPWMKLFFKIKPLLKSAETEKEMATMKE 860
            +LAR  + +  ++  A+  IQ N  +++ +++W W +LF K+KPLL+    E+EM   ++
Sbjct: 807  YLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKED 866

Query: 861  EFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCDQLIKTKIQ 920
            E QK K+   K+E + KELE+K   L +EKN LQ Q+QAE E  A+AEE   +L   K +
Sbjct: 867  ELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQE 926

Query: 921  LEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENK 980
            LE  + E+  R E+EE+   +L A+++K+  +  +L++ +++ E    K++ EK   E K
Sbjct: 927  LEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAK 986

Query: 981  VKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDL 1040
            +K L +E+  +D+   KL+KE+K L+E       +L  EE+K   LTK K K E  + +L
Sbjct: 987  IKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISEL 1046

Query: 1041 EGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKI 1100
            E  L++E+K R +LE+ KRKLEGD     E I D++ +  +L  +L KKE E+    +++
Sbjct: 1047 EVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARL 1106

Query: 1101 EDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAG 1160
            +DE A      KKI+EL+  I +L+E++++ERA+R KAEKQ+ DL  ELE +   LE+  
Sbjct: 1107 DDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTL 1166

Query: 1161 GATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVK 1220
             +T+ Q E+  KRE E   +++ L+E T  HEA    +R+KHA +V EL EQ++  +R K
Sbjct: 1167 DSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAK 1226

Query: 1221 QKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLT 1280
              L+K K  ++ E  DLA  +  + +AK  +E   + LE Q+ EL+SK  + +R   +L 
Sbjct: 1227 ANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELN 1286

Query: 1281 AQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQ 1340
             +  +LQ E    +  L+E E    +L++   + + Q+++ +  L+EE + K  ++  L+
Sbjct: 1287 DKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLR 1346

Query: 1341 SSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLA 1400
                + + L++Q +EE E+K  L+R +S  N +++  + K + D     E LEE KK+  
Sbjct: 1347 QLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQ-DFASTVEALEEGKKRFQ 1405

Query: 1401 QRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILA 1460
            + ++   +  E   A    LEKTK RLQ E++DL++D++      + L+KKQR FD++LA
Sbjct: 1406 KEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLA 1465

Query: 1461 EWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTE 1520
            E K    +   E + ++ EAR   T+   +  A EE+L+  E L+R NK L+ E+ DL  
Sbjct: 1466 EEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVS 1525

Query: 1521 QIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDR 1580
               + GK +HELEK K+ +E +  E++  LEE E  L+  E   LR+++ +  +K + +R
Sbjct: 1526 SKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFER 1585

Query: 1581 KIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANR 1640
             +  +DE+ ++ +R   R +   ++ L+ E + R  A   KKK+EGDL ++E+Q + A +
Sbjct: 1586 DLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIK 1645

Query: 1641 MAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQ 1700
               EA++  R  Q  +KD Q  L+DA  S++++       E++A  L+A++ +L+  L  
Sbjct: 1646 GREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAA 1705

Query: 1701 TERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEK 1760
             ER+RK A+ E  + +E +    +   +L + K++LE  I+Q++ E+E+         ++
Sbjct: 1706 AERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDR 1765

Query: 1761 AKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQK 1820
             +KA   A  ++ EL  E+ T+   E  ++ +E+  K+L+ +L E E       K  I  
Sbjct: 1766 VRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAA 1825

Query: 1821 LEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAK 1880
            LEA++ +LE +VE E +    A K L++ ++++KE+  Q E++RK   + ++  +K  A+
Sbjct: 1826 LEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNAR 1885

Query: 1881 VKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAESQVNKLRVKSR 1931
            VK  KRQ EEAEE+S    A  RKLQ EL+EA E  +    +VN L+ K R
Sbjct: 1886 VKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLR 1936



 Score =  216 bits (549), Expect = 2e-55
 Identities = 189/902 (20%), Positives = 433/902 (48%), Gaps = 53/902 (5%)

Query: 1083 DEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQR 1142
            +E+++ KE E+   + + +  +    +L++K  +L      L+E+++AE    A+AE+ R
Sbjct: 858  EEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMR 917

Query: 1143 SDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRR---DLEEATLQHEATAATLR 1199
              L+ + +E+ E L E       + +  ++ +AE +KM +   DLEE   + EA    L+
Sbjct: 918  VRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQ 977

Query: 1200 KKHADSVAE---LGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCR 1256
             +   + A+   L ++I  +     KL KE+  ++  I DL +N+    +   NL K+  
Sbjct: 978  LEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKN 1037

Query: 1257 TLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQ 1316
              E  +SEL+ + +++++   +L   + +L+ ++ +F  Q+ + +A +++L        +
Sbjct: 1038 KHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEE 1097

Query: 1317 QIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQ 1376
            +++    +L++EI  KN     ++        L+E  + E+ ++ + ++       E+  
Sbjct: 1098 ELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEA 1157

Query: 1377 WRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHV-EAVNAKCASLEKTKQRLQNEVEDLM 1435
             +T+ E D +  T   +E + K  Q +   ++ + E   +  A +++ +Q+    VE+L 
Sbjct: 1158 LKTELE-DTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELT 1216

Query: 1436 LDVERTNAACAALDKKQRNFDK----------ILAEWKQKCEETHAELEASQKEARS--- 1482
              +E+   A A LDK ++  +K          +L + KQ+ E    +LEA  +E +S   
Sbjct: 1217 EQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCS 1276

Query: 1483 --------LGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEK 1534
                    L  ++ K++N  E     L   + +   L ++++ L+ Q+ +  + + E  +
Sbjct: 1277 DGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETR 1336

Query: 1535 IK-------KQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDE 1587
             K       +Q+E+E+  LQ  L+E   + ++ E  I  + ++L+  K ++ +  A   E
Sbjct: 1337 QKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKL-QDFASTVE 1395

Query: 1588 EIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALR 1647
             +++ K+   + +E++    + +  + +   + K +++ +L+++ + L++  ++ +   +
Sbjct: 1396 ALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEK 1455

Query: 1648 NYRNTQGILKD----TQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTER 1703
              R    +L +    +  + D+  R++ + +E+    E +A  L   +EE     E+ ER
Sbjct: 1456 KQRKFDQLLAEEKNISSKYADERDRAEAEAREK----ETKALSLARALEEALEAKEELER 1511

Query: 1704 SRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEE-KAK 1762
            + K+ + E+ D       +      L  +K+ LET + +M+ ++E++  E +  E+ K +
Sbjct: 1512 TNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLR 1571

Query: 1763 KAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRL-DEAEQLALKGGKKQIQKL 1821
              +   A+  +  +  Q      E  ++ +++ + + +  L DE +Q AL    K+  KL
Sbjct: 1572 LEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKK--KL 1629

Query: 1822 EARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKV 1881
            E  +++LE + +S  K   EA+K LRK + ++K+   + E+ R +   +     + + K 
Sbjct: 1630 EGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKA 1689

Query: 1882 KSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAESQV--NKLRVKSREVHTKVIS 1939
            KS   +A+  + Q +   A+  + Q +LE+ E   ++A S    N L+ + R +  ++  
Sbjct: 1690 KSL--EADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQ 1747

Query: 1940 EE 1941
             E
Sbjct: 1748 LE 1749



 Score = 75.5 bits (184), Expect = 5e-13
 Identities = 59/271 (21%), Positives = 119/271 (43%), Gaps = 8/271 (2%)

Query: 1668 RSQEDLK---EQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHT 1724
            R +E+++   ++L   + R    + E++EL     Q    + + +++L   +E       
Sbjct: 856  RQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEE 915

Query: 1725 QNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAH 1784
                L   K++LE  + +M+  +E+     +  + + KK       + E+L++E+     
Sbjct: 916  MRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQK 975

Query: 1785 LERMKKNMEQTVKDLQLRLDEAEQLALKGGK--KQIQKLEARVRELEGEVESEQKRNAEA 1842
            L+  K   E  +K L+   DE   +  +  K  K+ + LE R+ +L   +  E+++    
Sbjct: 976  LQLEKVTAEAKIKKLE---DEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNL 1032

Query: 1843 VKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKF 1902
             K   KHE  + EL  + +++ K+   L+ L  KL+     +  Q  + + Q      + 
Sbjct: 1033 TKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQL 1092

Query: 1903 RKLQHELEEAEERADIAESQVNKLRVKSREV 1933
             K + EL+ A  R D   +Q N    K RE+
Sbjct: 1093 AKKEEELQAALARLDDEIAQKNNALKKIREL 1123


>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
            sapiens]
          Length = 1938

 Score = 1423 bits (3683), Expect = 0.0
 Identities = 779/1908 (40%), Positives = 1181/1908 (61%), Gaps = 20/1908 (1%)

Query: 34   AKTSVFVAEPKESFVKGTIQSREGGKVTVK-TEGGATLTVKDDQVFPMNPPKYDKIEDMA 92
            AK  V+V   K+ F   +I+  +G +V V+  E G  +TV  D +  MNPPK+ K+EDMA
Sbjct: 32   AKRLVWVPSEKQGFEAASIKEEKGDEVVVELVENGKKVTVGKDDIQKMNPPKFSKVEDMA 91

Query: 93   MMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYKPEVVTAYRGKKRQEAP 152
             +T L+E +VL+NL+ERY + +IYTYSGLFCV VNPYK LP+Y  ++V  Y+GKKR E P
Sbjct: 92   ELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKRHEMP 151

Query: 153  PHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKEEITS 212
            PHI++I+D AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY A +A + + KK+    
Sbjct: 152  PHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKDT--- 208

Query: 213  GKIQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLE 272
              I G LE Q++ ANP+LEAFGNAKTV+NDNSSRFGKFIRI+F  TG +  A+IETYLLE
Sbjct: 209  -SITGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLE 267

Query: 273  KSRVVFQLKAERSYHIFYQITSNKKPELIEMLLITTNPYDYPFVSQGEISVASIDDQEEL 332
            KSR + Q + ER++HIFY + +  K ++   LL+     +Y F+S G + + +  D E  
Sbjct: 268  KSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLE-GFNNYTFLSNGFVPIPAAQDDEMF 326

Query: 333  MATDSAIDILGFTNEEKVSIYKLTGAVMHYGNLKFKQKQREEQAEPDGTEVADKAAYLQS 392
              T  A+ I+GF+ EE++SI K+  +V+  GN+ FK+++  +QA       A K  +L  
Sbjct: 327  QETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKVCHLMG 386

Query: 393  LNSADLLKALCYPRVKVGNEYVTKGQTVEQVSNAVGALAKAVYEKMFLWMVARINQQLD- 451
            +N  D  +++  PR+KVG + V K QT EQ   AV ALAKA YE++F W++ R+N+ LD 
Sbjct: 387  INVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRVNKALDK 446

Query: 452  TKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEW 511
            T +    F+G+LDIAGFEIF+ NS EQLCIN+TNEKLQQ FNH MF+LEQEEY++EGIEW
Sbjct: 447  THRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEW 506

Query: 512  TFIDFGMDLAACIELIEKPM---GIFSILEEECMFPKATDTSFKNKLYDQHLGKSANFQK 568
             FIDFG+DL  CIELIE+P    G+ ++L+EEC FPKATD SF  KL  +  G    FQK
Sbjct: 507  NFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQ-GSHPKFQK 565

Query: 569  PKVVKGKAEAHFALIHYAGVVDYNITGWLEKNKDPLNETVVGLYQKSAMKTLAQLFSGAQ 628
            PK +K K E  F++IHYAG VDYN + WL KN DPLN+ V  L   S+ K +A L+    
Sbjct: 566  PKQLKDKTE--FSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLWKDVD 623

Query: 629  TAEG-----EGAGGGAKKGGKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPNE 683
               G     +          K K   F+TV  L++E L KLMT LR+T P+FVRCIIPN 
Sbjct: 624  RIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCIIPNH 683

Query: 684  TKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQFID 743
             K  G ++  LVL QLRCNGVLEGIRICR+GFP+RI++ +F+QRY++L A+AIP+G F+D
Sbjct: 684  EKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKG-FMD 742

Query: 744  SKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDDKLAQLITRTQARCRGFLA 803
             K+A   ++ ++++D   Y+ G +K+FF+ G+L  LEE RD K+  +I   QA CRG+LA
Sbjct: 743  GKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRGYLA 802

Query: 804  RVEYQRMVERREAIFCIQYNIRSFMNVKHWPWMKLFFKIKPLLKSAETEKEMATMKEEFQ 863
            R  + +  ++  A+  IQ N  +++ +++W W +LF K+KPLL+    E+EM   ++E Q
Sbjct: 803  RKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKEDELQ 862

Query: 864  KIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCDQLIKTKIQLEA 923
            K K+   K+E + KELE+K   L +EKN LQ Q+QAE E  A+AEE   +L   K +LE 
Sbjct: 863  KTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEE 922

Query: 924  KIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKN 983
             + E+  R E+EE+   +L A+++K+  +  +L++ +++ E    K++ EK   E K+K 
Sbjct: 923  ILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKK 982

Query: 984  LTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGS 1043
            L +E+  +D+   KL+KE+K L+E       +L  EE+K   LTK K K E  + +LE  
Sbjct: 983  LEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVR 1042

Query: 1044 LEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDE 1103
            L++E+K R +LE+ KRKLEGD     E I D++ +  +L  +L KKE E+    ++++DE
Sbjct: 1043 LKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDE 1102

Query: 1104 QALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGAT 1163
             A      KKI+EL+  I +L+E++++ERA+R KAEKQ+ DL  ELE +   LE+   +T
Sbjct: 1103 IAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDST 1162

Query: 1164 SAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKL 1223
            + Q E+  KRE E   +++ L+E T  HEA    +R+KHA +V EL EQ++  +R K  L
Sbjct: 1163 ATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANL 1222

Query: 1224 EKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQR 1283
            +K K  ++ E  DLA  +  + +AK  +E   + LE Q+ EL+SK  + +R   +L  + 
Sbjct: 1223 DKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKV 1282

Query: 1284 GRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSR 1343
             +LQ E    +  L+E E    +L++   + + Q+++ +  L+EE + K  ++  L+   
Sbjct: 1283 HKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLE 1342

Query: 1344 HDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRL 1403
             + + L++Q +EE E+K  L+R +S  N +++  + K + D     E LEE KK+  + +
Sbjct: 1343 EERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQ-DFASTVEALEEGKKRFQKEI 1401

Query: 1404 QAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWK 1463
            +   +  E   A    LEKTK RLQ E++DL++D++      + L+KKQR FD++LAE K
Sbjct: 1402 ENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEK 1461

Query: 1464 QKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIA 1523
                +   E + ++ EAR   T+   +  A EE+L+  E L+R NK L+ E+ DL     
Sbjct: 1462 NISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKD 1521

Query: 1524 EGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIA 1583
            + GK +HELEK K+ +E +  E++  LEE E  L+  E   LR+++ +  +K + +R + 
Sbjct: 1522 DVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQ 1581

Query: 1584 EKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAA 1643
             +DE+ ++ +R   R +   ++ L+ E + R  A   KKK+EGDL ++E+Q + A +   
Sbjct: 1582 ARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGRE 1641

Query: 1644 EALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTER 1703
            EA++  R  Q  +KD Q  L+DA  S++++       E++A  L+A++ +L+  L   ER
Sbjct: 1642 EAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAER 1701

Query: 1704 SRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKK 1763
            +RK A+ E  + +E +    +   +L + K++LE  I+Q++ E+E+         ++ +K
Sbjct: 1702 ARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRK 1761

Query: 1764 AITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEA 1823
            A   A  ++ EL  E+ T+   E  ++ +E+  K+L+ +L E E       K  I  LEA
Sbjct: 1762 ATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEA 1821

Query: 1824 RVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKS 1883
            ++ +LE +VE E +    A K L++ ++++KE+  Q E++RK   + ++  +K  A+VK 
Sbjct: 1822 KIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQ 1881

Query: 1884 YKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAESQVNKLRVKSR 1931
             KRQ EEAEE+S    A  RKLQ EL+EA E  +    +VN L+ K R
Sbjct: 1882 LKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLR 1929



 Score =  216 bits (549), Expect = 2e-55
 Identities = 189/902 (20%), Positives = 433/902 (48%), Gaps = 53/902 (5%)

Query: 1083 DEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQR 1142
            +E+++ KE E+   + + +  +    +L++K  +L      L+E+++AE    A+AE+ R
Sbjct: 851  EEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMR 910

Query: 1143 SDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRR---DLEEATLQHEATAATLR 1199
              L+ + +E+ E L E       + +  ++ +AE +KM +   DLEE   + EA    L+
Sbjct: 911  VRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQ 970

Query: 1200 KKHADSVAE---LGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCR 1256
             +   + A+   L ++I  +     KL KE+  ++  I DL +N+    +   NL K+  
Sbjct: 971  LEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKN 1030

Query: 1257 TLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQ 1316
              E  +SEL+ + +++++   +L   + +L+ ++ +F  Q+ + +A +++L        +
Sbjct: 1031 KHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEE 1090

Query: 1317 QIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQ 1376
            +++    +L++EI  KN     ++        L+E  + E+ ++ + ++       E+  
Sbjct: 1091 ELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEA 1150

Query: 1377 WRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHV-EAVNAKCASLEKTKQRLQNEVEDLM 1435
             +T+ E D +  T   +E + K  Q +   ++ + E   +  A +++ +Q+    VE+L 
Sbjct: 1151 LKTELE-DTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELT 1209

Query: 1436 LDVERTNAACAALDKKQRNFDK----------ILAEWKQKCEETHAELEASQKEARS--- 1482
              +E+   A A LDK ++  +K          +L + KQ+ E    +LEA  +E +S   
Sbjct: 1210 EQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCS 1269

Query: 1483 --------LGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEK 1534
                    L  ++ K++N  E     L   + +   L ++++ L+ Q+ +  + + E  +
Sbjct: 1270 DGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETR 1329

Query: 1535 IK-------KQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDE 1587
             K       +Q+E+E+  LQ  L+E   + ++ E  I  + ++L+  K ++ +  A   E
Sbjct: 1330 QKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKL-QDFASTVE 1388

Query: 1588 EIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALR 1647
             +++ K+   + +E++    + +  + +   + K +++ +L+++ + L++  ++ +   +
Sbjct: 1389 ALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEK 1448

Query: 1648 NYRNTQGILKD----TQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTER 1703
              R    +L +    +  + D+  R++ + +E+    E +A  L   +EE     E+ ER
Sbjct: 1449 KQRKFDQLLAEEKNISSKYADERDRAEAEAREK----ETKALSLARALEEALEAKEELER 1504

Query: 1704 SRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEE-KAK 1762
            + K+ + E+ D       +      L  +K+ LET + +M+ ++E++  E +  E+ K +
Sbjct: 1505 TNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLR 1564

Query: 1763 KAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRL-DEAEQLALKGGKKQIQKL 1821
              +   A+  +  +  Q      E  ++ +++ + + +  L DE +Q AL    K+  KL
Sbjct: 1565 LEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKK--KL 1622

Query: 1822 EARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKV 1881
            E  +++LE + +S  K   EA+K LRK + ++K+   + E+ R +   +     + + K 
Sbjct: 1623 EGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKA 1682

Query: 1882 KSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAESQV--NKLRVKSREVHTKVIS 1939
            KS   +A+  + Q +   A+  + Q +LE+ E   ++A S    N L+ + R +  ++  
Sbjct: 1683 KSL--EADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQ 1740

Query: 1940 EE 1941
             E
Sbjct: 1741 LE 1742



 Score = 75.5 bits (184), Expect = 5e-13
 Identities = 59/271 (21%), Positives = 119/271 (43%), Gaps = 8/271 (2%)

Query: 1668 RSQEDLK---EQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHT 1724
            R +E+++   ++L   + R    + E++EL     Q    + + +++L   +E       
Sbjct: 849  RQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEE 908

Query: 1725 QNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAH 1784
                L   K++LE  + +M+  +E+     +  + + KK       + E+L++E+     
Sbjct: 909  MRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQK 968

Query: 1785 LERMKKNMEQTVKDLQLRLDEAEQLALKGGK--KQIQKLEARVRELEGEVESEQKRNAEA 1842
            L+  K   E  +K L+   DE   +  +  K  K+ + LE R+ +L   +  E+++    
Sbjct: 969  LQLEKVTAEAKIKKLE---DEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNL 1025

Query: 1843 VKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKF 1902
             K   KHE  + EL  + +++ K+   L+ L  KL+     +  Q  + + Q      + 
Sbjct: 1026 TKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQL 1085

Query: 1903 RKLQHELEEAEERADIAESQVNKLRVKSREV 1933
             K + EL+ A  R D   +Q N    K RE+
Sbjct: 1086 AKKEEELQAALARLDDEIAQKNNALKKIREL 1116


>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
          Length = 1976

 Score = 1413 bits (3657), Expect = 0.0
 Identities = 774/1918 (40%), Positives = 1191/1918 (62%), Gaps = 26/1918 (1%)

Query: 27   AQNRPFDAKTSVFVAEPKESFVKGTIQSREGGKVTVK-TEGGATLTVKDDQVFPMNPPKY 85
            A    + AK  V++   +  F   +I+   G +V V+  E G    V  D +  MNPPK+
Sbjct: 25   ATQADWTAKKLVWIPSERHGFEAASIKEERGDEVMVELAENGKKAMVNKDDIQKMNPPKF 84

Query: 86   DKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYKPEVVTAYRG 145
             K+EDMA +T L+E +VL+NLK+RY + +IYTYSGLFCV +NPYK LP+Y   ++  YRG
Sbjct: 85   SKVEDMAELTCLNEASVLHNLKDRYYSGLIYTYSGLFCVVINPYKNLPIYSENIIEMYRG 144

Query: 146  KKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEK 205
            KKR E PPHI++IS++AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY A +A + + 
Sbjct: 145  KKRHEMPPHIYAISESAYRCMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSHKG 204

Query: 206  KKEEITSGKIQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASAD 265
            +K+      I G LE Q++ ANP+LE+FGNAKTV+NDNSSRFGKFIRI+F  TG +  A+
Sbjct: 205  RKDH----NIPGELERQLLQANPILESFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGAN 260

Query: 266  IETYLLEKSRVVFQLKAERSYHIFYQITSNKKPELIEMLLITTNPYDYPFVSQGEISVAS 325
            IETYLLEKSR V Q K ER++HIFYQ+ S     L   LL+     +Y F+S G I +  
Sbjct: 261  IETYLLEKSRAVRQAKDERTFHIFYQLLSGAGEHLKSDLLLE-GFNNYRFLSNGYIPIPG 319

Query: 326  IDDQEELMATDSAIDILGFTNEEKVSIYKLTGAVMHYGNLKFKQKQREEQAEPDGTEVAD 385
              D++    T  A+ I+GF++EE +S+ K+  +V+ +GN+ FK+++  +QA      VA 
Sbjct: 320  QQDKDNFQETMEAMHIMGFSHEEILSMLKVVSSVLQFGNISFKKERNTDQASMPENTVAQ 379

Query: 386  KAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTVEQVSNAVGALAKAVYEKMFLWMVAR 445
            K  +L  +N  +  +A+  PR+KVG +YV K QT EQ   AV ALAKA YE++F W+V R
Sbjct: 380  KLCHLLGMNVMEFTRAILTPRIKVGRDYVQKAQTKEQADFAVEALAKATYERLFRWLVHR 439

Query: 446  INQQLD-TKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEY 504
            IN+ LD TK+    FIG+LDIAGFEIF+ NS EQLCIN+TNEKLQQ FNH MF+LEQEEY
Sbjct: 440  INKALDRTKRQGASFIGILDIAGFEIFELNSFEQLCINYTNEKLQQLFNHTMFILEQEEY 499

Query: 505  KKEGIEWTFIDFGMDLAACIELIEKPM---GIFSILEEECMFPKATDTSFKNKLYDQHLG 561
            ++EGIEW FIDFG+DL  CI+LIE+P    G+ ++L+EEC FPKATD +F  KL  Q  G
Sbjct: 500  QREGIEWNFIDFGLDLQPCIDLIERPANPPGVLALLDEECWFPKATDKTFVEKLV-QEQG 558

Query: 562  KSANFQKPKVVKGKAEAHFALIHYAGVVDYNITGWLEKNKDPLNETVVGLYQKSAMKTLA 621
              + FQKP+ +K KA+  F +IHYAG VDY    WL KN DPLN+ V  L  +S+ + +A
Sbjct: 559  SHSKFQKPRQLKDKAD--FCIIHYAGKVDYKADEWLMKNMDPLNDNVATLLHQSSDRFVA 616

Query: 622  QLFSGAQTAEG--------EGAGGGAKKGGKKKGSSFQTVSALFRENLNKLMTNLRSTHP 673
            +L+       G        E A G A K   KKG  F+TV  L++E+L KLM  LR+T+P
Sbjct: 617  ELWKDVDRIVGLDQVTGMTETAFGSAYK--TKKGM-FRTVGQLYKESLTKLMATLRNTNP 673

Query: 674  HFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNA 733
            +FVRCIIPN  K  G ++  LVL QLRCNGVLEGIRICR+GFP+RI++ +F+QRY++L  
Sbjct: 674  NFVRCIIPNHEKRAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILTP 733

Query: 734  SAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDDKLAQLITR 793
            +AIP+G F+D K+A E+++ ++++D   Y+ G +K+FF+AG+L  LEE RD K+  +I  
Sbjct: 734  NAIPKG-FMDGKQACERMIRALELDPNLYRIGQSKIFFRAGVLAHLEEERDLKITDIIIF 792

Query: 794  TQARCRGFLARVEYQRMVERREAIFCIQYNIRSFMNVKHWPWMKLFFKIKPLLKSAETEK 853
             QA CRG+LAR  + +  ++  A+  +Q N  +++ ++HW W ++F K+KPLL+    E+
Sbjct: 793  FQAVCRGYLARKAFAKKQQQLSALKVLQRNCAAYLKLRHWQWWRVFTKVKPLLQVTRQEE 852

Query: 854  EMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCDQ 913
            E+    EE  K+K++  K E + +E+E K   LL+EKN L  Q+QAE E  A+AEE   +
Sbjct: 853  ELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMRAR 912

Query: 914  LIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKE 973
            L   K +LE  + ++  R E+EEE N  L  +K+K++    +L++ +D+ E    K++ E
Sbjct: 913  LAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLE 972

Query: 974  KHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKL 1033
            K   E K+K + EE+  L++  +K  KEKK +++   +    L  EE+K   L K + K 
Sbjct: 973  KVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQ 1032

Query: 1034 EQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEI 1093
            E  + DLE  L++E+K R +LE+AKRKL+G+    Q+ I +++ +  +L  +L KKE E+
Sbjct: 1033 EVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEEL 1092

Query: 1094 SNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEIS 1153
                ++ +DE        K ++ELQA+I EL+E+ E+E+ASR KAEKQ+ DLS ELE + 
Sbjct: 1093 QGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALK 1152

Query: 1154 ERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQI 1213
              LE+    T+AQ E+  KRE E  ++++ LEE T  HEA    +R++HA ++ EL EQ+
Sbjct: 1153 TELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQL 1212

Query: 1214 DNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQ 1273
            +  +R K  LEK K  ++ +  +LA  V+ + + K   E   + L+ Q+ EL +K  E  
Sbjct: 1213 EQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGD 1272

Query: 1274 RLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKN 1333
            RL  +L  +  +LQ E    S  L+E E    + ++   +   Q+++ +  L+EE + K 
Sbjct: 1273 RLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKL 1332

Query: 1334 ALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELE 1393
             L+  ++    + + L+EQ EEE+E++  L++ +    +++A  + K + D +   E LE
Sbjct: 1333 NLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDD-LGTIESLE 1391

Query: 1394 EAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQR 1453
            EAKKKL +  +A  + +E        LEKTK RLQ E++DL +D++      + L+KKQ+
Sbjct: 1392 EAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQK 1451

Query: 1454 NFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQ 1513
             FD++LAE K        E + ++ EAR   T+   +  A EE+L+  E  +R+NK L+ 
Sbjct: 1452 KFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRA 1511

Query: 1514 EISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQ 1573
            ++ DL     + GK +HELEK K+ +EQ+  E++  LEE E  L+  E   LR+++ +  
Sbjct: 1512 DMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQA 1571

Query: 1574 VKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEI 1633
            +K++ +R +  +DE+ ++ KR  I+ V  +++ L+ E + R  A+  KKKME DL ++E 
Sbjct: 1572 MKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEA 1631

Query: 1634 QLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEE 1693
            Q+  AN+   E ++  R  Q  +KD Q  L++A  S++++  Q    E++   L+AEI +
Sbjct: 1632 QIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQ 1691

Query: 1694 LRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQE 1753
            L+  L  +ER+R+ AEQE  + ++ +    +  ++L++ K++LE  I+Q++ E+E+    
Sbjct: 1692 LQEELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSN 1751

Query: 1754 ARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKG 1813
                 ++ +K       +  EL  E+  +   +  ++ +E+  K+L+ +L E E      
Sbjct: 1752 MELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSK 1811

Query: 1814 GKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDL 1873
             K  I  LEA++ +LE ++E E K  A A K +R+ E+++KE+  Q E++R++  + ++ 
Sbjct: 1812 FKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQ 1871

Query: 1874 VDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAESQVNKLRVKSR 1931
            ++K  A++K  KRQ EEAEE++    A  RKLQ EL++A E  +    +V+ L+ + R
Sbjct: 1872 MEKANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEANEGLSREVSTLKNRLR 1929



 Score =  254 bits (648), Expect = 7e-67
 Identities = 224/994 (22%), Positives = 464/994 (46%), Gaps = 125/994 (12%)

Query: 850  ETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTL-------LKEKNDLQLQVQAEAE 902
            + E+++   +   QK++ E   +EAK K++EE+++ L       +KEK  ++ ++   + 
Sbjct: 954  DLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSS 1013

Query: 903  GLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLE-------DECSE 955
             LA+ EE+   L K + + E  I ++ ER + EE+   EL   KRKL+       D+ +E
Sbjct: 1014 QLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAE 1073

Query: 956  LKKDIDDLELTLAKVEKE--------------KHATENKVKNLTEEMAGLDETIAK---- 997
            L+  ID+L+L LAK E+E              K+     V+ L  ++A L E        
Sbjct: 1074 LQAQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKAS 1133

Query: 998  ----------LTKEKKALQEAHQQTLDDLQAEED----KVNTLTKAKIKLEQQ------- 1036
                      L++E +AL+   + TLD   A+++    +   + + K  LE++       
Sbjct: 1134 RNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQ 1193

Query: 1037 -----------VDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEK 1085
                       +++L   LEQ K+ + +LE+ K+ LE D K     +  ++  K + + K
Sbjct: 1194 IQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHK 1253

Query: 1086 LKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDL 1145
             KK + ++  L +K+ +   L ++L +K  +LQ  ++ +   +E       K  K  + L
Sbjct: 1254 RKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASL 1313

Query: 1146 SRELEEISERLEEAG------GATSAQIEMNK----KREAEFQKMRRDLEEATLQHEATA 1195
              +L++  E L+E         +   Q+E  K    +++ E ++ R++LE+  L  ++  
Sbjct: 1314 ESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQL 1373

Query: 1196 ATLRKKHADSVAE-----------------LGEQIDNLQRVKQKLEKEKSEMKMEIDDLA 1238
            A  +KK  D +                   L ++++       KLEK K+ ++ E+DDL 
Sbjct: 1374 ADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLT 1433

Query: 1239 SNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLD 1298
             +++   +   NLEK  +  +  L+E KS         +   A+    +T++   +R L+
Sbjct: 1434 VDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALE 1493

Query: 1299 EKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALA---HALQSSRH----DCDLLRE 1351
            E           K+ F +Q ++L+  +E+ + +K+ +    H L+ S+       + +R 
Sbjct: 1494 EA-------LEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRT 1546

Query: 1352 QYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVE 1411
            Q EE ++     + A  +    +   + ++E D   R E+ EE K+ L ++++  E  +E
Sbjct: 1547 QLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELE 1606

Query: 1412 AVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEETHA 1471
                + A    +K++++ +++DL   +E  N A   + K+ R     + +++++ EE  A
Sbjct: 1607 DERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARA 1666

Query: 1472 -------ELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAE 1524
                   + + S+K+ +SL  E+ +++       ++L + +R  ++ +QE  +L ++I  
Sbjct: 1667 SRDEIFAQSKESEKKLKSLEAEILQLQ-------EELASSERARRHAEQERDELADEITN 1719

Query: 1525 GGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEV--DRKI 1582
                   L   K+++E    +L+  LEE ++++E    +  +  L+++ + +E+  +R  
Sbjct: 1720 SASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSA 1779

Query: 1583 AEK-DEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRM 1641
            A+K D    QL+R +  +   +Q  L+  ++S+  A      +E  + ++E QL    + 
Sbjct: 1780 AQKSDNARQQLERQNKELKAKLQE-LEGAVKSKFKATI--SALEAKIGQLEEQLEQEAKE 1836

Query: 1642 AAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQT 1701
             A A +  R T+  LK+  + ++D  R  +  KEQ+     R   L+ ++EE      + 
Sbjct: 1837 RAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRA 1896

Query: 1702 ERSRKIAEQELLDASERVQLLHTQNTSLINTKKK 1735
              SR+  ++EL DA+E  + L  + ++L N  ++
Sbjct: 1897 NASRRKLQRELDDATEANEGLSREVSTLKNRLRR 1930



 Score =  195 bits (496), Expect = 3e-49
 Identities = 203/912 (22%), Positives = 405/912 (44%), Gaps = 113/912 (12%)

Query: 1076 ENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASR 1135
            E E Q  DE+L K    +   Q+K+E E     ++++K ++L      L E+++AE    
Sbjct: 851  EEELQAKDEELLK----VKEKQTKVEGELE---EMERKHQQLLEEKNILAEQLQAETELF 903

Query: 1136 AKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATA 1195
            A+AE+ R+ L+ + +E+ E L +       + E N+  + E +KM+  +++         
Sbjct: 904  AEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQD--------- 954

Query: 1196 ATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMC 1255
                         L EQ+D  +  +QKL+ EK   + +I  +   +  +        K  
Sbjct: 955  -------------LEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEK 1001

Query: 1256 RTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFT 1315
            + +ED+++E  S+  E++    +L   R + +    +   +L ++E    +L + K+   
Sbjct: 1002 KLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLD 1061

Query: 1316 QQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVA 1375
             +  +L+ Q+ E           LQ+     D L+ Q  +++E   ELQ AL++ + E  
Sbjct: 1062 GETTDLQDQIAE-----------LQAQ---IDELKLQLAKKEE---ELQGALARGDDE-- 1102

Query: 1376 QWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLM 1435
               T ++ +A++   EL+    +L       +E  E+  A     EK K+ L  E+E L 
Sbjct: 1103 ---TLHKNNALKVVRELQAQIAEL-------QEDFESEKASRNKAEKQKRDLSEELEALK 1152

Query: 1436 LDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYE 1495
             ++E T    AA  + +   ++ +AE K+  EE     EA  ++ R       +   A E
Sbjct: 1153 TELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQ------RHATALE 1206

Query: 1496 ESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEA 1555
            E  +QLE  KR   NL++    L     E    +  L+++K + E ++ +L A ++E  A
Sbjct: 1207 ELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHA 1266

Query: 1556 SLEHEEGKILRIQL--ELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRS 1613
             +   EG  LR++L  + +++++E+D  ++   EE ++      +   S++S L      
Sbjct: 1267 KVS--EGDRLRVELAEKASKLQNELDN-VSTLLEEAEKKGIKFAKDAASLESQLQDTQEL 1323

Query: 1614 RNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNT-------QGILKDTQIHLDDA 1666
              +  R K  +   + ++E + N       E     +N        Q  L DT+  +DD 
Sbjct: 1324 LQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDD 1383

Query: 1667 LRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQN 1726
            L + E L+E    + + A  L   +EE     ++ E+++   +QEL D +  +       
Sbjct: 1384 LGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVA 1443

Query: 1727 TSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLE 1786
            ++L   +KK +  +++ +       +E   AE +A++  T A  +A  L++  +     E
Sbjct: 1444 SNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFE 1503

Query: 1787 RMKKNMEQTVKDLQLRLDEAE------QLALKGGKKQIQKLEARVRELEGEVESEQKR-- 1838
            R  K +   ++DL    D+        + + +  ++Q++++  ++ ELE E+++ +    
Sbjct: 1504 RQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKL 1563

Query: 1839 ----NAEAVKGLRKHE----------------RRVKELTYQTEEDRKNILRLQDLVDKLQ 1878
                N +A+K   + +                ++V+EL  + E++RK          K++
Sbjct: 1564 RLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKME 1623

Query: 1879 AKVKSYKRQAEEAEEQSNTNLAKFRKLQ-------HELEEAEERAD--IAESQVNKLRVK 1929
              +K  + Q E A +  +  + + RKLQ        ELEEA    D   A+S+ ++ ++K
Sbjct: 1624 IDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLK 1683

Query: 1930 SREVHTKVISEE 1941
            S E     + EE
Sbjct: 1684 SLEAEILQLQEE 1695



 Score =  175 bits (444), Expect = 3e-43
 Identities = 167/748 (22%), Positives = 351/748 (46%), Gaps = 64/748 (8%)

Query: 853  KEMATMKEEFQKIKDELAKSEAKRKELEEKM--------------VTLLKEKNDLQLQVQ 898
            KE+A   +  Q++K   A+SE KRK+L+ ++              V L ++ + LQ ++ 
Sbjct: 1234 KELACEVKVLQQVK---AESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELD 1290

Query: 899  AEAEGLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKK 958
              +  L +AE++  +  K    LE+++++  E  ++E      L+++ R+LE+E + L++
Sbjct: 1291 NVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQE 1350

Query: 959  DIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKAL---QEAHQQTLDD 1015
              ++ E     +EK+  A ++++ +  +++     TI  L + KK L    EA  Q L++
Sbjct: 1351 QQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEE 1410

Query: 1016 LQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDI 1075
                 DK   L K K +L+Q++DDL   L+ ++++  +LE+ ++K   D  LA+E  +  
Sbjct: 1411 KALAYDK---LEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKF--DQLLAEEKSISA 1465

Query: 1076 E--NEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERA 1133
                E+ + + + ++KE +  +L   +E+      + +++ K+L+A +E+L    +    
Sbjct: 1466 RYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGK 1525

Query: 1134 SRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMR----RDLEEATL 1189
            +  + EK +  L +++EE+  +LEE      A  +   + E   Q M+    RDL+    
Sbjct: 1526 NVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDE 1585

Query: 1190 QHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKG 1249
            Q+E     L K+    V EL  ++++ ++ +      K +M++++ DL + +E  +KA+ 
Sbjct: 1586 QNEEKKRLLIKQ----VRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARD 1641

Query: 1250 NLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLS- 1308
             + K  R L+ Q+       ++ QR + +  A R  +  +S E  ++L   EA + QL  
Sbjct: 1642 EVIKQLRKLQAQM-------KDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQE 1694

Query: 1309 ------RGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAE 1362
                  R ++   Q+ +EL  ++      K+AL    +        L E+ EEEQ +   
Sbjct: 1695 ELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMEL 1754

Query: 1363 LQRALSKANTEVAQWRTKY--ETDAIQRTE----ELEEAKKKLAQRLQAAEEHVEA-VNA 1415
            L     K   +V     +   E  A Q+++    +LE   K+L  +LQ  E  V++   A
Sbjct: 1755 LNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSKFKA 1814

Query: 1416 KCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNF-------DKILAEWKQKCEE 1468
              ++LE    +L+ ++E    +    N      +KK +          +   ++K++ E+
Sbjct: 1815 TISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEK 1874

Query: 1469 THAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGK- 1527
             +A ++  +++      E  +   +  +   +L+     N+ L +E+S L  ++  GG  
Sbjct: 1875 ANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEANEGLSREVSTLKNRLRRGGPI 1934

Query: 1528 RIHELEKIKKQVEQEKCELQAALEEAEA 1555
                    ++Q+  E   L+ + ++ E+
Sbjct: 1935 SFSSSRSGRRQLHLEGASLELSDDDTES 1962


>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
          Length = 1960

 Score = 1410 bits (3651), Expect = 0.0
 Identities = 771/1909 (40%), Positives = 1179/1909 (61%), Gaps = 25/1909 (1%)

Query: 34   AKTSVFVAEPKESFVKGTIQSREGGKVTVK-TEGGATLTVKDDQVFPMNPPKYDKIEDMA 92
            AK  V+V   K  F   +++   G +  V+  E G  + V  D +  MNPPK+ K+EDMA
Sbjct: 28   AKKLVWVPSDKSGFEPASLKEEVGEEAIVELVENGKKVKVNKDDIQKMNPPKFSKVEDMA 87

Query: 93   MMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYKPEVVTAYRGKKRQEAP 152
             +T L+E +VL+NLKERY + +IYTYSGLFCV +NPYK LP+Y  E+V  Y+GKKR E P
Sbjct: 88   ELTCLNEASVLHNLKERYYSGLIYTYSGLFCVVINPYKNLPIYSEEIVEMYKGKKRHEMP 147

Query: 153  PHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKEEITS 212
            PHI++I+D AY+ M+ DRE+QSIL TGESGAGKT NTK+VIQY A +A + + KK+    
Sbjct: 148  PHIYAITDTAYRSMMQDREDQSILCTGESGAGKTENTKKVIQYLAYVASSHKSKKD---- 203

Query: 213  GKIQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLE 272
               QG LE Q++ ANP+LEAFGNAKTV+NDNSSRFGKFIRI+F   G +  A+IETYLLE
Sbjct: 204  ---QGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVNGYIVGANIETYLLE 260

Query: 273  KSRVVFQLKAERSYHIFYQITSNKKPELIEMLLITTNPYD-YPFVSQGEISVASIDDQEE 331
            KSR + Q K ER++HIFY + S     L   LL+   PY+ Y F+S G +++    D++ 
Sbjct: 261  KSRAIRQAKEERTFHIFYYLLSGAGEHLKTDLLL--EPYNKYRFLSNGHVTIPGQQDKDM 318

Query: 332  LMATDSAIDILGFTNEEKVSIYKLTGAVMHYGNLKFKQKQREEQAEPDGTEVADKAAYLQ 391
               T  A+ I+G   EE++ + ++   V+  GN+ FK+++  +QA       A K ++L 
Sbjct: 319  FQETMEAMRIMGIPEEEQMGLLRVISGVLQLGNIVFKKERNTDQASMPDNTAAQKVSHLL 378

Query: 392  SLNSADLLKALCYPRVKVGNEYVTKGQTVEQVSNAVGALAKAVYEKMFLWMVARINQQLD 451
             +N  D  + +  PR+KVG +YV K QT EQ   A+ ALAKA YE+MF W+V RIN+ LD
Sbjct: 379  GINVTDFTRGILTPRIKVGRDYVQKAQTKEQADFAIEALAKATYERMFRWLVLRINKALD 438

Query: 452  -TKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIE 510
             TK+    FIG+LDIAGFEIFD NS EQLCIN+TNEKLQQ FNH MF+LEQEEY++EGIE
Sbjct: 439  KTKRQGASFIGILDIAGFEIFDLNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIE 498

Query: 511  WTFIDFGMDLAACIELIEKPMG---IFSILEEECMFPKATDTSFKNKLYDQHLGKSANFQ 567
            W FIDFG+DL  CI+LIEKP G   I ++L+EEC FPKATD SF  K+  Q  G    FQ
Sbjct: 499  WNFIDFGLDLQPCIDLIEKPAGPPGILALLDEECWFPKATDKSFVEKVM-QEQGTHPKFQ 557

Query: 568  KPKVVKGKAEAHFALIHYAGVVDYNITGWLEKNKDPLNETVVGLYQKSAMKTLAQLFSGA 627
            KPK +K KA+  F +IHYAG VDY    WL KN DPLN+ +  L  +S+ K +++L+   
Sbjct: 558  KPKQLKDKAD--FCIIHYAGKVDYKADEWLMKNMDPLNDNIATLLHQSSDKFVSELWKDV 615

Query: 628  QTAEGEGAGGGAKKGG-----KKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPN 682
                G     G  +       K +   F+TV  L++E L KLM  LR+T+P+FVRCIIPN
Sbjct: 616  DRIIGLDQVAGMSETALPGAFKTRKGMFRTVGQLYKEQLAKLMATLRNTNPNFVRCIIPN 675

Query: 683  ETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQFI 742
              K  G ++  LVL QLRCNGVLEGIRICR+GFP+R+++ +F+QRY++L  ++IP+G F+
Sbjct: 676  HEKKAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRVVFQEFRQRYEILTPNSIPKG-FM 734

Query: 743  DSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDDKLAQLITRTQARCRGFL 802
            D K+A   ++ ++++D   Y+ G +KVFF+AG+L  LEE RD K+  +I   QA CRG+L
Sbjct: 735  DGKQACVLMIKALELDSNLYRIGQSKVFFRAGVLAHLEEERDLKITDVIIGFQACCRGYL 794

Query: 803  ARVEYQRMVERREAIFCIQYNIRSFMNVKHWPWMKLFFKIKPLLKSAETEKEMATMKEEF 862
            AR  + +  ++  A+  +Q N  +++ +++W W +LF K+KPLL+ +  E+EM   +EE 
Sbjct: 795  ARKAFAKRQQQLTAMKVLQRNCAAYLKLRNWQWWRLFTKVKPLLQVSRQEEEMMAKEEEL 854

Query: 863  QKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCDQLIKTKIQLE 922
             K++++   +E +  E+E     L+ EK  LQ Q+QAE E  A+AEE   +L   K +LE
Sbjct: 855  VKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEELRARLTAKKQELE 914

Query: 923  AKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVK 982
                ++  R E+EEE    L A+K+K++    EL++ +++ E    K++ EK  TE K+K
Sbjct: 915  EICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLK 974

Query: 983  NLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEG 1042
             L EE   L++   KL KEKK L++   +   +L  EE+K  +L K K K E  + DLE 
Sbjct: 975  KLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEE 1034

Query: 1043 SLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIED 1102
             L +E+K R +LE+ +RKLEGD     + I +++ +  +L  +L KKE E+    +++E+
Sbjct: 1035 RLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEE 1094

Query: 1103 EQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGA 1162
            E A      KKI+EL+++I EL+E++E+ERASR KAEKQ+ DL  ELE +   LE+   +
Sbjct: 1095 EAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDS 1154

Query: 1163 TSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQK 1222
            T+AQ E+  KRE E   +++ LEE    HEA    +R+KH+ +V EL EQ++  +RVK  
Sbjct: 1155 TAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKAN 1214

Query: 1223 LEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQ 1282
            LEK K  ++ E  +LA+ V+ + + KG+ E   + +E QL EL+ K  E +R+  +L  +
Sbjct: 1215 LEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADK 1274

Query: 1283 RGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSS 1342
              +LQ E    +  L + ++  S+L++   A   Q+++ +  L+EE + K +L+  L+  
Sbjct: 1275 VTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQV 1334

Query: 1343 RHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQR 1402
              + +  REQ EEE+E+K  L++ ++  + +VA  + K E D++   E  EE K+KL + 
Sbjct: 1335 EDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKME-DSVGCLETAEEVKRKLQKD 1393

Query: 1403 LQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEW 1462
            L+   +  E   A    LEKTK RLQ E++DL++D++    +   L+KKQ+ FD++LAE 
Sbjct: 1394 LEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEE 1453

Query: 1463 KQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQI 1522
            K    +   E + ++ EAR   T+   +  A EE+++Q   L+R NK  + E+ DL    
Sbjct: 1454 KTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSK 1513

Query: 1523 AEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKI 1582
             + GK +HELEK K+ +EQ+  E++  LEE E  L+  E   LR+++ L  +K++ +R +
Sbjct: 1514 DDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDL 1573

Query: 1583 AEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMA 1642
              +DE+ ++ K+  +R V  M++ L+ E + R+ A+  +KK+E DL ++E  ++ AN+  
Sbjct: 1574 QGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNR 1633

Query: 1643 AEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTE 1702
             EA++  R  Q  +KD    LDD   S+E++  Q    E++   ++AE+ +L+  L   E
Sbjct: 1634 DEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAE 1693

Query: 1703 RSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAK 1762
            R+++ A+QE  + ++ +     +    +  K++LE  I+Q++ E+E+         ++ K
Sbjct: 1694 RAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDRLK 1753

Query: 1763 KAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLE 1822
            KA      +  +L  E+  +   E  ++ +E+  K+L+++L E E       K  I  LE
Sbjct: 1754 KANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKASITALE 1813

Query: 1823 ARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVK 1882
            A++ +LE ++++E K    A K +R+ E+++K++  Q +++R+N  + +D  DK   ++K
Sbjct: 1814 AKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLK 1873

Query: 1883 SYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAESQVNKLRVKSR 1931
              KRQ EEAEE++    A  RKLQ ELE+A E AD    +V+ L+ K R
Sbjct: 1874 QLKRQLEEAEEEAQRANASRRKLQRELEDATETADAMNREVSSLKNKLR 1922



 Score =  264 bits (675), Expect = 6e-70
 Identities = 234/986 (23%), Positives = 457/986 (46%), Gaps = 109/986 (11%)

Query: 850  ETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTL-------LKEKNDLQLQVQAEAE 902
            E E+++   +   QK++ E   +EAK K+LEE+ + L        KEK  L+ ++     
Sbjct: 947  ELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTT 1006

Query: 903  GLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLE-------DECSE 955
             L + EE+   L K K + EA I ++ ER   EE+   EL   +RKLE       D+ +E
Sbjct: 1007 NLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAE 1066

Query: 956  LKKDIDDLELTLAKVEKE--------------KHATENKVKNLTEEMAGLDETIAK---- 997
            L+  I +L++ LAK E+E              K+    K++ L  +++ L E +      
Sbjct: 1067 LQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERAS 1126

Query: 998  ----------LTKEKKALQEAHQQTLDDLQAE-------EDKVNTLTKA----------- 1029
                      L +E +AL+   + TLD   A+       E +VN L K            
Sbjct: 1127 RNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQ 1186

Query: 1030 ----KIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEK 1085
                + K  Q V++L   LEQ K+++ +LE+AK+ LE +       +  +   K   + K
Sbjct: 1187 IQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHK 1246

Query: 1086 LKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDL 1145
             KK E ++  LQ K  + + +  +L  K+ +LQ  ++ +   +    +  +K  K  S L
Sbjct: 1247 RKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSAL 1306

Query: 1146 SRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEE------------ATLQHEA 1193
              +L++  E L+E      +     K+ E E    R  LEE            ATL   A
Sbjct: 1307 ESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLH--A 1364

Query: 1194 TAATLRKKHADSVA--ELGEQID-----NLQRVKQ----------KLEKEKSEMKMEIDD 1236
              A ++KK  DSV   E  E++      +L+ + Q          KLEK K+ ++ E+DD
Sbjct: 1365 QVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDD 1424

Query: 1237 LASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQ 1296
            L  +++   ++  NLEK  +  +  L+E K+   +     +   A+    +T++   +R 
Sbjct: 1425 LLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARA 1484

Query: 1297 LDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEE 1356
            L+E     ++L R  + F  ++E+L    ++  K+ + L  + ++     + ++ Q EE 
Sbjct: 1485 LEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEEL 1544

Query: 1357 QESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAK 1416
            ++     + A  +    +   + ++E D   R E+ EE KK+L ++++  E  +E    +
Sbjct: 1545 EDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQ 1604

Query: 1417 CASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEAS 1476
             +     +++L+ +++DL   ++  N       K+ R     + +  ++ ++T A  E  
Sbjct: 1605 RSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEI 1664

Query: 1477 QKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEG-GKRIHELEKI 1535
              +A+    +L  ++    +  ++L   +R  +  QQE  +L ++IA   GK    LE+ 
Sbjct: 1665 LAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEE- 1723

Query: 1536 KKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEV--DRKIAEKDEEI-DQL 1592
            K+++E    +L+  LEE + + E    ++ +  L+++Q+ +++  +R  A+K+E    QL
Sbjct: 1724 KRRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQL 1783

Query: 1593 KRNHIRI---VESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNY 1649
            +R +  +   ++ M+ T+ ++ ++   A+  K      + ++E QL++  +    A +  
Sbjct: 1784 ERQNKELKVKLQEMEGTVKSKYKASITALEAK------IAQLEEQLDNETKERQAACKQV 1837

Query: 1650 RNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAE 1709
            R T+  LKD  + +DD  R+ E  K+Q      R   L+ ++EE     ++   SR+  +
Sbjct: 1838 RRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQ 1897

Query: 1710 QELLDASERVQLLHTQNTSLINTKKK 1735
            +EL DA+E    ++ + +SL N  ++
Sbjct: 1898 RELEDATETADAMNREVSSLKNKLRR 1923



 Score =  236 bits (602), Expect = 2e-61
 Identities = 202/976 (20%), Positives = 456/976 (46%), Gaps = 82/976 (8%)

Query: 999  TKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAK 1058
            TK K  LQ + Q+  +++ A+E+++  + + ++  E ++ ++E        L+  L   K
Sbjct: 832  TKVKPLLQVSRQE--EEMMAKEEELVKVREKQLAAENRLTEME-------TLQSQLMAEK 882

Query: 1059 RKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQ 1118
             +L+  L+   E   + E  + +L  K ++ E    +L++++E+E+     LQ + K++Q
Sbjct: 883  LQLQEQLQAETELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQ 942

Query: 1119 ARIEELEEEIEAERASRAKAEKQRSDLSRELEEISER---LEEAGGATSAQIEMNKKREA 1175
              I+ELEE++E E ++R K + ++     +L+++ E    LE+     + + ++ + R A
Sbjct: 943  QNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIA 1002

Query: 1176 EFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEID 1235
            EF     + EE +     + A L+ KH   + +L E++   ++ +Q+LEK + +++ +  
Sbjct: 1003 EFTTNLTEEEEKS----KSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDST 1058

Query: 1236 DLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSR 1295
            DL+  +                L+ Q++ELK +  +++    +L A   R++ E+ + + 
Sbjct: 1059 DLSDQIAE--------------LQAQIAELKMQLAKKEE---ELQAALARVEEEAAQKNM 1101

Query: 1296 QLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEE 1355
             L +   L SQ+S           EL+  LE E  ++N      +    + + L+ + E+
Sbjct: 1102 ALKKIRELESQIS-----------ELQEDLESERASRNKAEKQKRDLGEELEALKTELED 1150

Query: 1356 EQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNA 1415
              +S A  Q   SK   EV   +   E +A     +++E ++K +Q ++   E +E    
Sbjct: 1151 TLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKR 1210

Query: 1416 KCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEA 1475
              A+LEK KQ L+NE  +L  +V+         + K++  +  L E + K  E       
Sbjct: 1211 VKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTE 1270

Query: 1476 SQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKI 1535
               +   L  EL  +     +S  +   L ++   L+ ++ D  E + E  ++   L   
Sbjct: 1271 LADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTK 1330

Query: 1536 KKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRN 1595
             KQVE EK   +  LEE E +  + E +I  +  ++  +K +++  +    E  +++KR 
Sbjct: 1331 LKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCL-ETAEEVKRK 1389

Query: 1596 HIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGI 1655
              + +E +    + ++ + +   + K +++ +L+++ + L+H  + A    +  +    +
Sbjct: 1390 LQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQL 1449

Query: 1656 L---------------------KDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEEL 1694
            L                     ++ +       R+ E+  EQ A +ER     + E+E+L
Sbjct: 1450 LAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDL 1509

Query: 1695 RAT-------LEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQMQGEM 1747
             ++       + + E+S++  EQ++ +   +++ L  +  +  + K +LE ++  M+ + 
Sbjct: 1510 MSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQF 1569

Query: 1748 EDILQ-EARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEA 1806
            E  LQ     +EEK K+ +     M  EL+ E+   +     +K +E  +KDL+  +D A
Sbjct: 1570 ERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSA 1629

Query: 1807 EQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKN 1866
             +   +   KQ++KL+A++++   E++  +    E +   +++E+++K +  +  + ++ 
Sbjct: 1630 NKNRDEA-IKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEE 1688

Query: 1867 IL-------RLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIA 1919
            +        + Q   D+L  ++ +   +   A E+     A+  +L+ ELEE +   ++ 
Sbjct: 1689 LAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELI 1748

Query: 1920 ESQVNKLRVKSREVHT 1935
              ++ K  ++  +++T
Sbjct: 1749 NDRLKKANLQIDQINT 1764



 Score =  187 bits (476), Expect = 7e-47
 Identities = 213/913 (23%), Positives = 393/913 (43%), Gaps = 122/913 (13%)

Query: 1083 DEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQR 1142
            +E++  KE E+  ++ K    +    +++    +L A   +L+E+++AE    A+AE+ R
Sbjct: 844  EEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEELR 903

Query: 1143 SDLS---RELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLR 1199
            + L+   +ELEEI   LE                       R + EE   QH       +
Sbjct: 904  ARLTAKKQELEEICHDLEA----------------------RVEEEEERCQHLQAE---K 938

Query: 1200 KKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLE 1259
            KK   ++ EL EQ++  +  +QKL+ EK             V T +K K  LE+    LE
Sbjct: 939  KKMQQNIQELEEQLEEEESARQKLQLEK-------------VTTEAKLK-KLEEEQIILE 984

Query: 1260 DQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIE 1319
            DQ  +L     ++++L+ D  A          EF+  L E+E     L++ K      I 
Sbjct: 985  DQNCKLA----KEKKLLEDRIA----------EFTTNLTEEEEKSKSLAKLKNKHEAMIT 1030

Query: 1320 ELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRT 1379
            +L+ +L  E K +  L    +    D   L +Q  E Q   AEL+  L+K   E+     
Sbjct: 1031 DLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALA 1090

Query: 1380 KYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVE 1439
            + E +A Q+   L++ ++ L  ++   +E +E+  A     EK K+ L  E+E L  ++E
Sbjct: 1091 RVEEEAAQKNMALKKIRE-LESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELE 1149

Query: 1440 RTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLD 1499
             T  + AA  + +   ++ +   K+  EE     EA  +E R       K   A EE  +
Sbjct: 1150 DTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQ------KHSQAVEELAE 1203

Query: 1500 QLETLKRENKNLQQEISDLTEQIAEGGKRIHEL-------EKIKKQVEQEKCELQAALEE 1552
            QLE  KR   NL++    L  +  E    +  L       E  +K+VE +  ELQ    E
Sbjct: 1204 QLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNE 1263

Query: 1553 AEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQST---LDA 1609
             E        K+ ++Q+EL+ V       +++ D +  +L ++   +   +Q T   L  
Sbjct: 1264 GERVRTELADKVTKLQVELDNVTG----LLSQSDSKSSKLTKDFSALESQLQDTQELLQE 1319

Query: 1610 EIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRS 1669
            E R +       K++E + N    QL           +        + D +  ++D++  
Sbjct: 1320 ENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGC 1379

Query: 1670 QEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSL 1729
             E  +E    +++    L    EE  A  ++ E+++   +QEL D    V L H Q  S 
Sbjct: 1380 LETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLL--VDLDH-QRQSA 1436

Query: 1730 INTKKKLETDISQMQGEMEDI----LQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHL 1785
             N +KK +    Q+  E + I     +E   AE +A++  T A  +A  L++  +  A L
Sbjct: 1437 CNLEKK-QKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAEL 1495

Query: 1786 ERMKKNMEQTVKDLQLRLDEAE------QLALKGGKKQIQKLEARVRELEGEVESEQKR- 1838
            ER+ K     ++DL    D+        + + +  ++Q+++++ ++ ELE E+++ +   
Sbjct: 1496 ERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAK 1555

Query: 1839 -----NAEAVKGLRKHE----------------RRVKELTYQTEEDRKNILRLQDLVDKL 1877
                 N +A+K   + +                R+V+E+  + E++RK          KL
Sbjct: 1556 LRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKL 1615

Query: 1878 QAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERAD---------IAESQVNKLRV 1928
            +  +K  +   + A +  +  + + RKLQ ++++     D         +A+++ N+ ++
Sbjct: 1616 EMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKL 1675

Query: 1929 KSREVHTKVISEE 1941
            KS E     + EE
Sbjct: 1676 KSMEAEMIQLQEE 1688



 Score =  117 bits (292), Expect = 1e-25
 Identities = 125/578 (21%), Positives = 257/578 (44%), Gaps = 68/578 (11%)

Query: 1386 IQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAAC 1445
            +Q + + EE   K  + ++  E+ + A N +   +E  + +L  E   L   ++     C
Sbjct: 838  LQVSRQEEEMMAKEEELVKVREKQLAAEN-RLTEMETLQSQLMAEKLQLQEQLQAETELC 896

Query: 1446 AALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLK 1505
            A                  + EE  A L A ++E   +  +L   +   EE  ++ + L+
Sbjct: 897  A------------------EAEELRARLTAKKQELEEICHDL---EARVEEEEERCQHLQ 935

Query: 1506 RENKNLQQEISDLTEQIAE--GGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGK 1563
             E K +QQ I +L EQ+ E    ++  +LEK+  + + +K      LEE +  LE +  K
Sbjct: 936  AEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKK------LEEEQIILEDQNCK 989

Query: 1564 ILRIQLELNQVKSEVDRKIAEKDEE---IDQLKRNHIRIVESMQSTLDAEIRSRNDAIRL 1620
            + + +  L    +E    + E++E+   + +LK  H  ++  ++  L  E + R +  + 
Sbjct: 990  LAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKT 1049

Query: 1621 KKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMV 1680
            ++K+EGD  ++  Q+       AE           L   +  L  AL   E+   Q  M 
Sbjct: 1050 RRKLEGDSTDLSDQIAELQAQIAELKMQ-------LAKKEEELQAALARVEEEAAQKNMA 1102

Query: 1681 ERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINT-------- 1732
             ++   L+++I EL+  LE    SR  AE++  D  E ++ L T+    +++        
Sbjct: 1103 LKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELR 1162

Query: 1733 -KKKLETDISQMQGEMEDILQEARNAE--EKAKKAITDAAMMAEELKKEQDTSAHLERMK 1789
             K++ E +I +   E E    EA+  E  +K  +A+ +   +AE+L++ +   A+LE+ K
Sbjct: 1163 SKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEE---LAEQLEQTKRVKANLEKAK 1219

Query: 1790 KNMEQTVKDLQLRLDEAEQLALKG---GKKQIQKLEARVRELEGEVESEQKRNAEAVKGL 1846
                QT+++ +  L    ++ L+G    + + +K+EA+++EL+ +    ++   E    +
Sbjct: 1220 ----QTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKV 1275

Query: 1847 RKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQ 1906
             K +  +  +T    +      +L      L+++++  +   +E   Q  +   K ++++
Sbjct: 1276 TKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVE 1335

Query: 1907 HE-------LEEAEERADIAESQVNKLRVKSREVHTKV 1937
             E       LEE EE     E Q+  L  +  ++  K+
Sbjct: 1336 DEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKM 1373



 Score = 86.7 bits (213), Expect = 2e-16
 Identities = 75/379 (19%), Positives = 167/379 (44%), Gaps = 33/379 (8%)

Query: 837  KLFFKIKPLLKSAETEKEMATMKEEFQKIKDELAKS----EAKRKELEEKMVTLLKEKND 892
            KL  ++      A+ E+++    E+ ++ K +L +     EA+ ++  ++    +  +  
Sbjct: 1555 KLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKK 1614

Query: 893  LQLQVQAEAEGLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDE 952
            L++ ++     +  A +  D+ IK   +L+A++K+     +D      E+ A+ ++ E +
Sbjct: 1615 LEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKK 1674

Query: 953  CSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQT 1012
               ++ ++  L+  LA  E+ K   + +   L +E+A      A   +EK+ L+    Q 
Sbjct: 1675 LKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQL 1734

Query: 1013 LDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKK-------LRMDLERAKRKL---- 1061
             ++L+ E+     +     K   Q+D +   L  E+         R  LER  ++L    
Sbjct: 1735 EEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKL 1794

Query: 1062 ---EGDLKLAQE-SIMDIENEKQQLDEKL--------------KKKEFEISNLQSKIEDE 1103
               EG +K   + SI  +E +  QL+E+L              ++ E ++ ++  +++DE
Sbjct: 1795 QEMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDE 1854

Query: 1104 QALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGAT 1163
            +    Q + +  +   R+++L+ ++E       +A   R  L RELE+ +E  +      
Sbjct: 1855 RRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETADAMNREV 1914

Query: 1164 SAQIEMNKKREAEFQKMRR 1182
            S+     ++ +  F   RR
Sbjct: 1915 SSLKNKLRRGDLPFVVPRR 1933



 Score = 42.7 bits (99), Expect = 0.003
 Identities = 69/332 (20%), Positives = 142/332 (42%), Gaps = 67/332 (20%)

Query: 783  RDDKLAQLITRTQARCRGFLARVEYQRMVERREAIFCIQYNIRSFMNVKHWPWMKLFFKI 842
            RD+ + QL  + QA+ +  +  ++  R   R E +   + N +   +++         ++
Sbjct: 1633 RDEAIKQL-RKLQAQMKDCMRELDDTR-ASREEILAQAKENEKKLKSME-----AEMIQL 1685

Query: 843  KPLLKSAETEKEMATMKEEFQKIKDELAKSEAK-------RKELEEKMVTLLKEKNDLQL 895
            +  L +AE  K  A  ++E  ++ DE+A S  K       ++ LE ++  L +E  + Q 
Sbjct: 1686 QEELAAAERAKRQA--QQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQG 1743

Query: 896  QVQAEAEGLADAEERCDQLI--------------KTKIQLEAKIKEVTERAEDEE----- 936
              +   + L  A  + DQ+                 + QLE + KE+  + ++ E     
Sbjct: 1744 NTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKS 1803

Query: 937  EINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIA 996
            +  A +TA    LE + ++L++ +D+         KE+ A   +V+              
Sbjct: 1804 KYKASITA----LEAKIAQLEEQLDN-------ETKERQAACKQVR-------------- 1838

Query: 997  KLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLER 1056
               + +K L++   Q  D+ +  E   +   KA  +L+Q    L+  LE+ ++       
Sbjct: 1839 ---RTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQ----LKRQLEEAEEEAQRANA 1891

Query: 1057 AKRKLEGDLKLAQESIMDIENEKQQLDEKLKK 1088
            ++RKL+ +L+ A E+   +  E   L  KL++
Sbjct: 1892 SRRKLQRELEDATETADAMNREVSSLKNKLRR 1923



 Score = 38.5 bits (88), Expect = 0.065
 Identities = 36/149 (24%), Positives = 70/149 (46%), Gaps = 13/149 (8%)

Query: 1799 LQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTY 1858
            LQ+   E E +A +    ++++ +        E+E+ Q +       L++  +   EL  
Sbjct: 838  LQVSRQEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCA 897

Query: 1859 QTEEDRKNIL----RLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEE 1914
            + EE R  +      L+++   L+A+V       EE EE+     A+ +K+Q  ++E EE
Sbjct: 898  EAEELRARLTAKKQELEEICHDLEARV-------EEEEERCQHLQAEKKKMQQNIQELEE 950

Query: 1915 RADIAESQVNKLRVK--SREVHTKVISEE 1941
            + +  ES   KL+++  + E   K + EE
Sbjct: 951  QLEEEESARQKLQLEKVTTEAKLKKLEEE 979


>gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens]
          Length = 1995

 Score = 1306 bits (3380), Expect = 0.0
 Identities = 722/1907 (37%), Positives = 1151/1907 (60%), Gaps = 21/1907 (1%)

Query: 34   AKTSVFVAEPKESFVKGTIQSREGGKVTVK-TEGGATLTVKDDQVFPMNPPKYDKIEDMA 92
            A+  V+V      F    ++     +  V+  E G  L +  DQ+  MNPPK+ K EDMA
Sbjct: 52   ARRLVWVPSELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMA 111

Query: 93   MMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYKPEVVTAYRGKKRQEAP 152
             +T L+E +VL+NL+ERY + +IYTYSGLFCV +NPYK LP+Y   +V  YRGKKR E P
Sbjct: 112  ELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVP 171

Query: 153  PHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKEEITS 212
            PH++++++ AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY A +A + + +KE    
Sbjct: 172  PHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEP--- 228

Query: 213  GKIQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLE 272
              + G LE Q++ ANP+LEAFGNAKTV+NDNSSRFGKFIRI+F   G +  A+IETYLLE
Sbjct: 229  -GVPGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLLE 287

Query: 273  KSRVVFQLKAERSYHIFYQITSNKKPELIEMLLITTNPYDYPFVSQGEISVASIDDQEEL 332
            KSR + Q K E S+HIFYQ+      +L   LL+    + Y F++ G  S     ++E  
Sbjct: 288  KSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSH-YRFLTNGPSSSPG-QERELF 345

Query: 333  MATDSAIDILGFTNEEKVSIYKLTGAVMHYGNLKFKQKQREEQAEPDGTEVADKAAYLQS 392
              T  ++ +LGF++EE +S+ ++  AV+ +GN+  K+++  +QA       A K   L  
Sbjct: 346  QETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRLLG 405

Query: 393  LNSADLLKALCYPRVKVGNEYVTKGQTVEQVSNAVGALAKAVYEKMFLWMVARINQQLDT 452
            L   D  +AL  PR+KVG +YV K QT EQ   A+ ALAKA YE++F W+V R+N+ LD 
Sbjct: 406  LGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALD- 464

Query: 453  KQPRQ--YFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIE 510
            + PRQ   F+G+LDIAGFEIF  NS EQLCIN+TNEKLQQ FNH MFVLEQEEY++EGI 
Sbjct: 465  RSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIP 524

Query: 511  WTFIDFGMDLAACIELIEKPM---GIFSILEEECMFPKATDTSFKNKLYDQHLGKSANFQ 567
            WTF+DFG+DL  CI+LIE+P    G+ ++L+EEC FPKATD SF  K+  Q  G    FQ
Sbjct: 525  WTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVA-QEQGGHPKFQ 583

Query: 568  KPKVVKGKAEAHFALIHYAGVVDYNITGWLEKNKDPLNETVVGLYQKSAMKTLAQLFS-- 625
            +P+ ++ +A+  F+++HYAG VDY    WL KN DPLN+ V  L  +S  +  A+++   
Sbjct: 584  RPRHLRDQAD--FSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKDV 641

Query: 626  -GAQTAEGEGAGGGAKKGGKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPNET 684
             G    E   + G    GG+ +   F+TV  L++E+L++LM  L +T+P FVRCI+PN  
Sbjct: 642  EGIVGLEQVSSLGDGPPGGRPRRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHE 701

Query: 685  KTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQFIDS 744
            K  G +E  LVL QLRCNGVLEGIRICR+GFP+RIL+ +F+QRY++L  +AIP+G F+D 
Sbjct: 702  KRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPKG-FMDG 760

Query: 745  KKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDDKLAQLITRTQARCRGFLAR 804
            K+A EK++ ++++D   Y+ G +K+FF+AG+L  LEE RD K+  +I   QA  RG+LAR
Sbjct: 761  KQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLAR 820

Query: 805  VEYQRMVERREAIFCIQYNIRSFMNVKHWPWMKLFFKIKPLLKSAETEKEMATMKEEFQK 864
              +Q+  +++ A+  +Q N  +++ ++HW W +LF K+KPLL+    ++ +    +E QK
Sbjct: 821  RAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQELQK 880

Query: 865  IKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCDQLIKTKIQLEAK 924
            +++   +S  +  EL+ ++  L +E+  L  Q++AEAE  A+AEE   +L   K +LE  
Sbjct: 881  VQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQELELV 940

Query: 925  IKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNL 984
            + E+  R  +EEE + ++  +K++L+    EL+  ++  E    K++ EK  TE K+K  
Sbjct: 941  VSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKF 1000

Query: 985  TEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSL 1044
             E++  L++  +KL+KE+K L++   +       EE+KV +L K ++K E  + D+E  L
Sbjct: 1001 EEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRL 1060

Query: 1045 EQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQ 1104
             +E+K R +LE+ KR+L+G+    QE +++ +   ++L  +L +KE E+    ++ EDE 
Sbjct: 1061 RKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEG 1120

Query: 1105 ALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATS 1164
                QL K ++E QA + E +E++E+ER +R KAEKQR DL  ELE +   LE+   +T+
Sbjct: 1121 GARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTN 1180

Query: 1165 AQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLE 1224
            AQ E+  KRE E  ++++ LEE T  HEA    LR++H  ++ EL EQ++  +R K   E
Sbjct: 1181 AQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWE 1240

Query: 1225 KEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRG 1284
            K +  ++ E+ +L + + ++  A+   E+  R LE QL E++ +  + +R   +   +  
Sbjct: 1241 KTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQ 1300

Query: 1285 RLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRH 1344
            R Q E    S  L+E E+   +LS+   +   Q+ + +  L+EE +AK AL   +++   
Sbjct: 1301 RAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEA 1360

Query: 1345 DCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQ 1404
            +   LREQ EEE  ++    R L  A  ++++WR + E +A    E  EEA+++ A+  +
Sbjct: 1361 EAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEA-GALEAGEEARRRAAREAE 1419

Query: 1405 AAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQ 1464
            A  + +         LE+ ++RLQ E++D  +D+E+     + L+KKQR FD++LAE K 
Sbjct: 1420 ALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKA 1479

Query: 1465 KCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAE 1524
                   E E ++ E R        +  A EE  +  E L+R+N+ L+ E+  L     +
Sbjct: 1480 AVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDD 1539

Query: 1525 GGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAE 1584
             GK +HELE+  +  EQ   +L+A + E E  L   E   LR+++ +  +K++ +R +  
Sbjct: 1540 VGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQG 1599

Query: 1585 KDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAE 1644
            +DE  ++ +R   + +   +   D E + R  A+  +KK+EG+L E++ Q+  A +   E
Sbjct: 1600 RDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEE 1659

Query: 1645 ALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERS 1704
            A++  R  Q  +K+    +++   S+E++  Q    E+R   L+AE+  L+  L  ++R+
Sbjct: 1660 AVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRA 1719

Query: 1705 RKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKA 1764
            R+ A+Q+  + ++ V   +    +++  K++LE  + Q++ E+E+    +    ++ +K 
Sbjct: 1720 RRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKL 1779

Query: 1765 ITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEAR 1824
            +     +  EL  E+  SA  E  ++ +E+ +++L+ RL E +  A    K  I  LE++
Sbjct: 1780 LLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESK 1839

Query: 1825 VRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSY 1884
            + + E ++E E +    + K +R+ E+R+KE+  Q EE+R+   +L+D ++K   +VK  
Sbjct: 1840 LAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQL 1899

Query: 1885 KRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAESQVNKLRVKSR 1931
            KRQ EEAEE+++   A  R+LQ ELE+  E A+    +V  LR + R
Sbjct: 1900 KRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLR 1946



 Score =  224 bits (572), Expect = 5e-58
 Identities = 195/932 (20%), Positives = 421/932 (45%), Gaps = 48/932 (5%)

Query: 859  KEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCD------ 912
            ++E +K+K  L   + +  EL+E+MV   +   +L+ Q+  + E L  A  R +      
Sbjct: 1067 RQELEKLKRRL---DGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGAR 1123

Query: 913  -QLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVE 971
             QL+K+  + +A + E  E  E E     +   ++R L +E   L+ +++D   TL    
Sbjct: 1124 AQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELED---TLDSTN 1180

Query: 972  KEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVN----TLT 1027
             ++     + + +TE    L+E         + L++ H Q L +L  + ++         
Sbjct: 1181 AQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWE 1240

Query: 1028 KAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLK 1087
            K ++ LE +V +L   L   +  R + E+ +R+LE  L+  Q    D E  + +  EKL+
Sbjct: 1241 KTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQ 1300

Query: 1088 KKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSR 1147
            + + E+ N+   + + ++  I+L K++   +A++ + +E ++ E  ++     +   +  
Sbjct: 1301 RAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEA 1360

Query: 1148 ELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADS-- 1205
            E   + E+LEE   A        +  +A+  + RR  EE     EA     R+   ++  
Sbjct: 1361 EAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEA 1420

Query: 1206 ----VAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQ 1261
                +AE  E +D L+R +++L++E  +  M+++     V T+ K +   +++    E++
Sbjct: 1421 LTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLA--EEK 1478

Query: 1262 LSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEEL 1321
             + L++ EE ++       A+    +  +   +R L+E++    +L R  +A   ++E L
Sbjct: 1479 AAVLRAVEERERA-----EAEGREREARALSLTRALEEEQEAREELERQNRALRAELEAL 1533

Query: 1322 KRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKY 1381
                ++  K+ + L  A + +    + LR Q  E ++     + A  +    V   +T++
Sbjct: 1534 LSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQH 1593

Query: 1382 ETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERT 1441
            E D   R E  EE +++LA++L+ AE   +    +       +++L+ E+E+L   +   
Sbjct: 1594 ERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASA 1653

Query: 1442 NAACAALDKKQRNFDKILAEWKQKCEETHAELEA-------SQKEARSLGTELFKIKNAY 1494
                    K+ R     + E  ++ EET    E        S+K  + L  E+ +++   
Sbjct: 1654 GQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQ--- 1710

Query: 1495 EESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAE 1554
                ++L    R  +  QQ+  ++ +++A G      + + K+Q+E    +L+  LEE +
Sbjct: 1711 ----EELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQ 1766

Query: 1555 ASLEHEEGKILRIQLELNQVKSEV--DRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIR 1612
            ++ E    +  ++ L++  + +E+  +R  + K E   Q     I+ +       DA  R
Sbjct: 1767 SNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGAR 1826

Query: 1613 SRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQED 1672
            +R+        +E  L + E QL    R    + +  R  +  LK+  + +++  R  + 
Sbjct: 1827 ARHKMTIAA--LESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQ 1884

Query: 1673 LKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINT 1732
            L++QL     R   L+ ++EE      + +  R+  ++EL D +E  + ++ + T+L N 
Sbjct: 1885 LRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNR 1944

Query: 1733 KKKLETDISQMQGEMEDILQEARNAEEKAKKA 1764
             ++     +         L+E   ++E+A++A
Sbjct: 1945 LRRGPLTFTTRTVRQVFRLEEGVASDEEAEEA 1976



 Score =  171 bits (434), Expect = 5e-42
 Identities = 178/881 (20%), Positives = 381/881 (43%), Gaps = 83/881 (9%)

Query: 1099 KIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEE 1158
            +++  Q L  Q  +++ ELQ R+ +LEEE    RA  A+  +  ++L  E EE   RL  
Sbjct: 877  ELQKVQELQQQSAREVGELQGRVAQLEEE----RARLAEQLRAEAELCAEAEETRGRLAA 932

Query: 1159 AGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQR 1218
                    +   + R  E ++  R ++           T +K+    + EL   ++  + 
Sbjct: 933  RKQELELVVSELEARVGEEEECSRQMQ-----------TEKKRLQQHIQELEAHLEAEEG 981

Query: 1219 VKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLIND 1278
             +QKL+ EK   + ++     ++  +      L K  + LED+L+E  S+  E++  +  
Sbjct: 982  ARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKS 1041

Query: 1279 LTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHA 1338
            L   R + +    +   +L ++E    +L + K+    +  EL+ Q+ E+ +    L   
Sbjct: 1042 LNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQ 1101

Query: 1339 LQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKK 1398
            L     +      + E+E  ++A+L ++L +A   +A+ +   E++ + RT+  E+ ++ 
Sbjct: 1102 LGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKA-EKQRRD 1160

Query: 1399 LAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVER-TNAACAALDKKQRNFDK 1457
            L + L+A    +E       + ++ + + + EV +L   +E  T    AA+ + ++   +
Sbjct: 1161 LGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQ 1220

Query: 1458 ILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISD 1517
             L E  ++ E+      A +K   +L  E+ +++      L  L+T ++E +  ++    
Sbjct: 1221 ALGELAEQLEQARRGKGAWEKTRLALEAEVSELR----AELSSLQTARQEGEQRRRR--- 1273

Query: 1518 LTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSE 1577
            L  Q+ E   R  + E+ + +  ++    QA LE    +L   E K +R+  EL+  +++
Sbjct: 1274 LELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQ 1333

Query: 1578 VDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNH 1637
            +                         Q  L  E R++       + ME +   +  QL  
Sbjct: 1334 L----------------------HDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEE 1371

Query: 1638 ANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRAT 1697
                   A R  +  Q  L + +   ++   + E  +E      R A  L   + E   T
Sbjct: 1372 EAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTET 1431

Query: 1698 LEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNA 1757
            +++ ER R+  +QEL DA+  ++      ++L   ++K +  +++ +  +   ++E   A
Sbjct: 1432 VDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERA 1491

Query: 1758 EEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAE------QLAL 1811
            E + ++    A  +   L++EQ+    LER  + +   ++ L    D+        + A 
Sbjct: 1492 EAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERAC 1551

Query: 1812 KGGKKQIQKLEARVRELEGEV---ESEQKRNAEAVKGLR-KHER---------------- 1851
            +  ++    L A+V ELE E+   E  + R    V+ L+ +HER                
Sbjct: 1552 RVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQL 1611

Query: 1852 --RVKELTYQTEEDRKNIL-------RLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKF 1902
              ++++   + +E+RK          +L+  +++L+A++ S  +  EEA +Q     A+ 
Sbjct: 1612 AKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQM 1671

Query: 1903 RKLQHELEEAEERAD--IAESQVNKLRVKSREVHTKVISEE 1941
            ++L  E+EE     +   ++++ ++ R+K  E     + EE
Sbjct: 1672 KELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEE 1712



 Score =  117 bits (292), Expect = 1e-25
 Identities = 130/642 (20%), Positives = 262/642 (40%), Gaps = 49/642 (7%)

Query: 1339 LQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKK 1398
            LQ+   +   ++E  ++      ELQ  +++   E A+   +   +A +   E EE + +
Sbjct: 871  LQARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEA-ELCAEAEETRGR 929

Query: 1399 LAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALD--KKQRNFD 1456
            LA R Q  E  V  + A+    E+  +++Q E + L   ++   A   A +  +++   +
Sbjct: 930  LAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLE 989

Query: 1457 KILAEWKQKCEETHAELEASQ-----KEARSLGTELFKIKNAYEESLDQLETLKRENKNL 1511
            K+  E K K  E    L   Q     KE + L   L +  +   E  +++++L +     
Sbjct: 990  KVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKY 1049

Query: 1512 QQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLEL 1571
            +  I+D+ +++ +  K   ELEK+K++++ E  ELQ  + E +   E    ++ R + EL
Sbjct: 1050 EATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEEL 1109

Query: 1572 NQVKS-----------------EVDRKIAEKDEEID----------QLKRNHIRIVESMQ 1604
                +                 E    +AE  E+++          + +R+    +E+++
Sbjct: 1110 QAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALR 1169

Query: 1605 STLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLD 1664
              L+  + S N    L+ K E ++ E++  L    R+   A++  R   G        L 
Sbjct: 1170 GELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQA------LG 1223

Query: 1665 DALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHT 1724
            +     E  +      E+    L+AE+ ELRA L   + +R+  EQ       ++Q +  
Sbjct: 1224 ELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQG 1283

Query: 1725 QNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAH 1784
            +       + +    + + Q E+E++      AE K  +   + +    +L   Q+    
Sbjct: 1284 RAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQE 1343

Query: 1785 LERMK-------KNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQK 1837
              R K       + ME     L+ +L+E E  A +   +++Q  +A++ E     E E  
Sbjct: 1344 ETRAKLALGSRVRAMEAEAAGLREQLEE-EAAARERAGRELQTAQAQLSEWRRRQEEEAG 1402

Query: 1838 RNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNT 1897
                  +  R+  R  + LT +  E  + + RL+    +LQ ++       E+  +  +T
Sbjct: 1403 ALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVST 1462

Query: 1898 NLAKFRKLQHELEEAEERADIAESQVNKLRVKSREVHTKVIS 1939
               K RK    L E +     A  +  +   + RE   + +S
Sbjct: 1463 LEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALS 1504


>gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens]
          Length = 2003

 Score = 1305 bits (3378), Expect = 0.0
 Identities = 722/1911 (37%), Positives = 1151/1911 (60%), Gaps = 21/1911 (1%)

Query: 34   AKTSVFVAEPKESFVKGTIQSREGGKVTVK-TEGGATLTVKDDQVFPMNPPKYDKIEDMA 92
            A+  V+V      F    ++     +  V+  E G  L +  DQ+  MNPPK+ K EDMA
Sbjct: 52   ARRLVWVPSELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMA 111

Query: 93   MMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYKPEVVTAYRGKKRQEAP 152
             +T L+E +VL+NL+ERY + +IYTYSGLFCV +NPYK LP+Y   +V  YRGKKR E P
Sbjct: 112  ELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVP 171

Query: 153  PHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKEEITS 212
            PH++++++ AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY A +A + + +KE    
Sbjct: 172  PHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVP 231

Query: 213  GKIQ----GTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIET 268
              +     G LE Q++ ANP+LEAFGNAKTV+NDNSSRFGKFIRI+F   G +  A+IET
Sbjct: 232  ASVSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIET 291

Query: 269  YLLEKSRVVFQLKAERSYHIFYQITSNKKPELIEMLLITTNPYDYPFVSQGEISVASIDD 328
            YLLEKSR + Q K E S+HIFYQ+      +L   LL+    + Y F++ G  S     +
Sbjct: 292  YLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSH-YRFLTNGPSSSPG-QE 349

Query: 329  QEELMATDSAIDILGFTNEEKVSIYKLTGAVMHYGNLKFKQKQREEQAEPDGTEVADKAA 388
            +E    T  ++ +LGF++EE +S+ ++  AV+ +GN+  K+++  +QA       A K  
Sbjct: 350  RELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLC 409

Query: 389  YLQSLNSADLLKALCYPRVKVGNEYVTKGQTVEQVSNAVGALAKAVYEKMFLWMVARINQ 448
             L  L   D  +AL  PR+KVG +YV K QT EQ   A+ ALAKA YE++F W+V R+N+
Sbjct: 410  RLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNR 469

Query: 449  QLDTKQPRQ--YFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKK 506
             LD + PRQ   F+G+LDIAGFEIF  NS EQLCIN+TNEKLQQ FNH MFVLEQEEY++
Sbjct: 470  ALD-RSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQR 528

Query: 507  EGIEWTFIDFGMDLAACIELIEKPM---GIFSILEEECMFPKATDTSFKNKLYDQHLGKS 563
            EGI WTF+DFG+DL  CI+LIE+P    G+ ++L+EEC FPKATD SF  K+  Q  G  
Sbjct: 529  EGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVA-QEQGGH 587

Query: 564  ANFQKPKVVKGKAEAHFALIHYAGVVDYNITGWLEKNKDPLNETVVGLYQKSAMKTLAQL 623
              FQ+P+ ++ +A+  F+++HYAG VDY    WL KN DPLN+ V  L  +S  +  A++
Sbjct: 588  PKFQRPRHLRDQAD--FSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEI 645

Query: 624  FS---GAQTAEGEGAGGGAKKGGKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCII 680
            +    G    E   + G    GG+ +   F+TV  L++E+L++LM  L +T+P FVRCI+
Sbjct: 646  WKDVEGIVGLEQVSSLGDGPPGGRPRRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCIV 705

Query: 681  PNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQ 740
            PN  K  G +E  LVL QLRCNGVLEGIRICR+GFP+RIL+ +F+QRY++L  +AIP+G 
Sbjct: 706  PNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPKG- 764

Query: 741  FIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDDKLAQLITRTQARCRG 800
            F+D K+A EK++ ++++D   Y+ G +K+FF+AG+L  LEE RD K+  +I   QA  RG
Sbjct: 765  FMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARG 824

Query: 801  FLARVEYQRMVERREAIFCIQYNIRSFMNVKHWPWMKLFFKIKPLLKSAETEKEMATMKE 860
            +LAR  +Q+  +++ A+  +Q N  +++ ++HW W +LF K+KPLL+    ++ +    +
Sbjct: 825  YLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQ 884

Query: 861  EFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCDQLIKTKIQ 920
            E QK+++   +S  +  EL+ ++  L +E+  L  Q++AEAE  A+AEE   +L   K +
Sbjct: 885  ELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQE 944

Query: 921  LEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENK 980
            LE  + E+  R  +EEE + ++  +K++L+    EL+  ++  E    K++ EK  TE K
Sbjct: 945  LELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAK 1004

Query: 981  VKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDL 1040
            +K   E++  L++  +KL+KE+K L++   +       EE+KV +L K ++K E  + D+
Sbjct: 1005 MKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADM 1064

Query: 1041 EGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKI 1100
            E  L +E+K R +LE+ KR+L+G+    QE +++ +   ++L  +L +KE E+    ++ 
Sbjct: 1065 EDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARA 1124

Query: 1101 EDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAG 1160
            EDE     QL K ++E QA + E +E++E+ER +R KAEKQR DL  ELE +   LE+  
Sbjct: 1125 EDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTL 1184

Query: 1161 GATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVK 1220
             +T+AQ E+  KRE E  ++++ LEE T  HEA    LR++H  ++ EL EQ++  +R K
Sbjct: 1185 DSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGK 1244

Query: 1221 QKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLT 1280
               EK +  ++ E+ +L + + ++  A+   E+  R LE QL E++ +  + +R   +  
Sbjct: 1245 GAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAA 1304

Query: 1281 AQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQ 1340
             +  R Q E    S  L+E E+   +LS+   +   Q+ + +  L+EE +AK AL   ++
Sbjct: 1305 EKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVR 1364

Query: 1341 SSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLA 1400
            +   +   LREQ EEE  ++    R L  A  ++++WR + E +A    E  EEA+++ A
Sbjct: 1365 AMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEA-GALEAGEEARRRAA 1423

Query: 1401 QRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILA 1460
            +  +A  + +         LE+ ++RLQ E++D  +D+E+     + L+KKQR FD++LA
Sbjct: 1424 REAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLA 1483

Query: 1461 EWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTE 1520
            E K        E E ++ E R        +  A EE  +  E L+R+N+ L+ E+  L  
Sbjct: 1484 EEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLS 1543

Query: 1521 QIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDR 1580
               + GK +HELE+  +  EQ   +L+A + E E  L   E   LR+++ +  +K++ +R
Sbjct: 1544 SKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHER 1603

Query: 1581 KIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANR 1640
             +  +DE  ++ +R   + +   +   D E + R  A+  +KK+EG+L E++ Q+  A +
Sbjct: 1604 DLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQ 1663

Query: 1641 MAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQ 1700
               EA++  R  Q  +K+    +++   S+E++  Q    E+R   L+AE+  L+  L  
Sbjct: 1664 GKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAA 1723

Query: 1701 TERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEK 1760
            ++R+R+ A+Q+  + ++ V   +    +++  K++LE  + Q++ E+E+    +    ++
Sbjct: 1724 SDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDR 1783

Query: 1761 AKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQK 1820
             +K +     +  EL  E+  SA  E  ++ +E+ +++L+ RL E +  A    K  I  
Sbjct: 1784 YRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAA 1843

Query: 1821 LEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAK 1880
            LE+++ + E ++E E +    + K +R+ E+R+KE+  Q EE+R+   +L+D ++K   +
Sbjct: 1844 LESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLR 1903

Query: 1881 VKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAESQVNKLRVKSR 1931
            VK  KRQ EEAEE+++   A  R+LQ ELE+  E A+    +V  LR + R
Sbjct: 1904 VKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLR 1954



 Score =  224 bits (572), Expect = 5e-58
 Identities = 195/932 (20%), Positives = 421/932 (45%), Gaps = 48/932 (5%)

Query: 859  KEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCD------ 912
            ++E +K+K  L   + +  EL+E+MV   +   +L+ Q+  + E L  A  R +      
Sbjct: 1075 RQELEKLKRRL---DGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGAR 1131

Query: 913  -QLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVE 971
             QL+K+  + +A + E  E  E E     +   ++R L +E   L+ +++D   TL    
Sbjct: 1132 AQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELED---TLDSTN 1188

Query: 972  KEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVN----TLT 1027
             ++     + + +TE    L+E         + L++ H Q L +L  + ++         
Sbjct: 1189 AQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWE 1248

Query: 1028 KAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLK 1087
            K ++ LE +V +L   L   +  R + E+ +R+LE  L+  Q    D E  + +  EKL+
Sbjct: 1249 KTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQ 1308

Query: 1088 KKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSR 1147
            + + E+ N+   + + ++  I+L K++   +A++ + +E ++ E  ++     +   +  
Sbjct: 1309 RAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEA 1368

Query: 1148 ELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADS-- 1205
            E   + E+LEE   A        +  +A+  + RR  EE     EA     R+   ++  
Sbjct: 1369 EAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEA 1428

Query: 1206 ----VAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQ 1261
                +AE  E +D L+R +++L++E  +  M+++     V T+ K +   +++    E++
Sbjct: 1429 LTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLA--EEK 1486

Query: 1262 LSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEEL 1321
             + L++ EE ++       A+    +  +   +R L+E++    +L R  +A   ++E L
Sbjct: 1487 AAVLRAVEERERA-----EAEGREREARALSLTRALEEEQEAREELERQNRALRAELEAL 1541

Query: 1322 KRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKY 1381
                ++  K+ + L  A + +    + LR Q  E ++     + A  +    V   +T++
Sbjct: 1542 LSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQH 1601

Query: 1382 ETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERT 1441
            E D   R E  EE +++LA++L+ AE   +    +       +++L+ E+E+L   +   
Sbjct: 1602 ERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASA 1661

Query: 1442 NAACAALDKKQRNFDKILAEWKQKCEETHAELEA-------SQKEARSLGTELFKIKNAY 1494
                    K+ R     + E  ++ EET    E        S+K  + L  E+ +++   
Sbjct: 1662 GQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQ--- 1718

Query: 1495 EESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAE 1554
                ++L    R  +  QQ+  ++ +++A G      + + K+Q+E    +L+  LEE +
Sbjct: 1719 ----EELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQ 1774

Query: 1555 ASLEHEEGKILRIQLELNQVKSEV--DRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIR 1612
            ++ E    +  ++ L++  + +E+  +R  + K E   Q     I+ +       DA  R
Sbjct: 1775 SNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGAR 1834

Query: 1613 SRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQED 1672
            +R+        +E  L + E QL    R    + +  R  +  LK+  + +++  R  + 
Sbjct: 1835 ARHKMTIAA--LESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQ 1892

Query: 1673 LKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINT 1732
            L++QL     R   L+ ++EE      + +  R+  ++EL D +E  + ++ + T+L N 
Sbjct: 1893 LRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNR 1952

Query: 1733 KKKLETDISQMQGEMEDILQEARNAEEKAKKA 1764
             ++     +         L+E   ++E+A++A
Sbjct: 1953 LRRGPLTFTTRTVRQVFRLEEGVASDEEAEEA 1984



 Score =  171 bits (434), Expect = 5e-42
 Identities = 178/881 (20%), Positives = 381/881 (43%), Gaps = 83/881 (9%)

Query: 1099 KIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEE 1158
            +++  Q L  Q  +++ ELQ R+ +LEEE    RA  A+  +  ++L  E EE   RL  
Sbjct: 885  ELQKVQELQQQSAREVGELQGRVAQLEEE----RARLAEQLRAEAELCAEAEETRGRLAA 940

Query: 1159 AGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQR 1218
                    +   + R  E ++  R ++           T +K+    + EL   ++  + 
Sbjct: 941  RKQELELVVSELEARVGEEEECSRQMQ-----------TEKKRLQQHIQELEAHLEAEEG 989

Query: 1219 VKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLIND 1278
             +QKL+ EK   + ++     ++  +      L K  + LED+L+E  S+  E++  +  
Sbjct: 990  ARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKS 1049

Query: 1279 LTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHA 1338
            L   R + +    +   +L ++E    +L + K+    +  EL+ Q+ E+ +    L   
Sbjct: 1050 LNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQ 1109

Query: 1339 LQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKK 1398
            L     +      + E+E  ++A+L ++L +A   +A+ +   E++ + RT+  E+ ++ 
Sbjct: 1110 LGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKA-EKQRRD 1168

Query: 1399 LAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVER-TNAACAALDKKQRNFDK 1457
            L + L+A    +E       + ++ + + + EV +L   +E  T    AA+ + ++   +
Sbjct: 1169 LGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQ 1228

Query: 1458 ILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISD 1517
             L E  ++ E+      A +K   +L  E+ +++      L  L+T ++E +  ++    
Sbjct: 1229 ALGELAEQLEQARRGKGAWEKTRLALEAEVSELR----AELSSLQTARQEGEQRRRR--- 1281

Query: 1518 LTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSE 1577
            L  Q+ E   R  + E+ + +  ++    QA LE    +L   E K +R+  EL+  +++
Sbjct: 1282 LELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQ 1341

Query: 1578 VDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNH 1637
            +                         Q  L  E R++       + ME +   +  QL  
Sbjct: 1342 L----------------------HDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEE 1379

Query: 1638 ANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRAT 1697
                   A R  +  Q  L + +   ++   + E  +E      R A  L   + E   T
Sbjct: 1380 EAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTET 1439

Query: 1698 LEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNA 1757
            +++ ER R+  +QEL DA+  ++      ++L   ++K +  +++ +  +   ++E   A
Sbjct: 1440 VDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERA 1499

Query: 1758 EEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAE------QLAL 1811
            E + ++    A  +   L++EQ+    LER  + +   ++ L    D+        + A 
Sbjct: 1500 EAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERAC 1559

Query: 1812 KGGKKQIQKLEARVRELEGEV---ESEQKRNAEAVKGLR-KHER---------------- 1851
            +  ++    L A+V ELE E+   E  + R    V+ L+ +HER                
Sbjct: 1560 RVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQL 1619

Query: 1852 --RVKELTYQTEEDRKNIL-------RLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKF 1902
              ++++   + +E+RK          +L+  +++L+A++ S  +  EEA +Q     A+ 
Sbjct: 1620 AKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQM 1679

Query: 1903 RKLQHELEEAEERAD--IAESQVNKLRVKSREVHTKVISEE 1941
            ++L  E+EE     +   ++++ ++ R+K  E     + EE
Sbjct: 1680 KELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEE 1720



 Score =  117 bits (292), Expect = 1e-25
 Identities = 130/642 (20%), Positives = 262/642 (40%), Gaps = 49/642 (7%)

Query: 1339 LQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKK 1398
            LQ+   +   ++E  ++      ELQ  +++   E A+   +   +A +   E EE + +
Sbjct: 879  LQARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEA-ELCAEAEETRGR 937

Query: 1399 LAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALD--KKQRNFD 1456
            LA R Q  E  V  + A+    E+  +++Q E + L   ++   A   A +  +++   +
Sbjct: 938  LAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLE 997

Query: 1457 KILAEWKQKCEETHAELEASQ-----KEARSLGTELFKIKNAYEESLDQLETLKRENKNL 1511
            K+  E K K  E    L   Q     KE + L   L +  +   E  +++++L +     
Sbjct: 998  KVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKY 1057

Query: 1512 QQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLEL 1571
            +  I+D+ +++ +  K   ELEK+K++++ E  ELQ  + E +   E    ++ R + EL
Sbjct: 1058 EATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEEL 1117

Query: 1572 NQVKS-----------------EVDRKIAEKDEEID----------QLKRNHIRIVESMQ 1604
                +                 E    +AE  E+++          + +R+    +E+++
Sbjct: 1118 QAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALR 1177

Query: 1605 STLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLD 1664
              L+  + S N    L+ K E ++ E++  L    R+   A++  R   G        L 
Sbjct: 1178 GELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQA------LG 1231

Query: 1665 DALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHT 1724
            +     E  +      E+    L+AE+ ELRA L   + +R+  EQ       ++Q +  
Sbjct: 1232 ELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQG 1291

Query: 1725 QNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAH 1784
            +       + +    + + Q E+E++      AE K  +   + +    +L   Q+    
Sbjct: 1292 RAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQE 1351

Query: 1785 LERMK-------KNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQK 1837
              R K       + ME     L+ +L+E E  A +   +++Q  +A++ E     E E  
Sbjct: 1352 ETRAKLALGSRVRAMEAEAAGLREQLEE-EAAARERAGRELQTAQAQLSEWRRRQEEEAG 1410

Query: 1838 RNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNT 1897
                  +  R+  R  + LT +  E  + + RL+    +LQ ++       E+  +  +T
Sbjct: 1411 ALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVST 1470

Query: 1898 NLAKFRKLQHELEEAEERADIAESQVNKLRVKSREVHTKVIS 1939
               K RK    L E +     A  +  +   + RE   + +S
Sbjct: 1471 LEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALS 1512


>gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens]
          Length = 2036

 Score = 1293 bits (3345), Expect = 0.0
 Identities = 722/1944 (37%), Positives = 1151/1944 (59%), Gaps = 54/1944 (2%)

Query: 34   AKTSVFVAEPKESFVKGTIQSREGGKVTVK-TEGGATLTVKDDQVFPMNPPKYDKIEDMA 92
            A+  V+V      F    ++     +  V+  E G  L +  DQ+  MNPPK+ K EDMA
Sbjct: 52   ARRLVWVPSELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMA 111

Query: 93   MMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYKPEVVTAYRGKKRQEAP 152
             +T L+E +VL+NL+ERY + +IYTYSGLFCV +NPYK LP+Y   +V  YRGKKR E P
Sbjct: 112  ELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVP 171

Query: 153  PHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKEEITS 212
            PH++++++ AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY A +A + + +KE    
Sbjct: 172  PHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVP 231

Query: 213  GKIQ----GTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIET 268
              +     G LE Q++ ANP+LEAFGNAKTV+NDNSSRFGKFIRI+F   G +  A+IET
Sbjct: 232  ASVSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIET 291

Query: 269  YLLEKSRVVFQLKAERSYHIFYQITSNKKPELIEMLLITTNPYDYPFVSQGEISVASIDD 328
            YLLEKSR + Q K E S+HIFYQ+      +L   LL+    + Y F++ G  S     +
Sbjct: 292  YLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSH-YRFLTNGPSSSPG-QE 349

Query: 329  QEELMATDSAIDILGFTNEEKVSIYKLTGAVMHYGNLKFKQKQREEQAEPDGTEVADKAA 388
            +E    T  ++ +LGF++EE +S+ ++  AV+ +GN+  K+++  +QA       A K  
Sbjct: 350  RELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLC 409

Query: 389  YLQSLNSADLLKALCYPRVKVGNEYVTKGQTVEQVSNAVGALAKAVYEKMFLWMVARINQ 448
             L  L   D  +AL  PR+KVG +YV K QT EQ   A+ ALAKA YE++F W+V R+N+
Sbjct: 410  RLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNR 469

Query: 449  QLDTKQPRQ--YFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKK 506
             LD + PRQ   F+G+LDIAGFEIF  NS EQLCIN+TNEKLQQ FNH MFVLEQEEY++
Sbjct: 470  ALD-RSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQR 528

Query: 507  EGIEWTFIDFGMDLAACIELIEKPM---GIFSILEEECMFPKATDTSFKNKLYDQHLGKS 563
            EGI WTF+DFG+DL  CI+LIE+P    G+ ++L+EEC FPKATD SF  K+  Q  G  
Sbjct: 529  EGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVA-QEQGGH 587

Query: 564  ANFQKPKVVKGKAEAHFALIHYAGVVDYNITGWLEKNKDPLNETVVGLYQKSAMKTLAQL 623
              FQ+P+ ++ +A+  F+++HYAG VDY    WL KN DPLN+ V  L  +S  +  A++
Sbjct: 588  PKFQRPRHLRDQAD--FSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEI 645

Query: 624  FS------------------------------------GAQTAEGEGAGGGAKKGGKKKG 647
            +                                     G    E   + G    GG+ + 
Sbjct: 646  WKDEHGGFQQFSFLGSFPPSPPGSAERCSSAISPPGVEGIVGLEQVSSLGDGPPGGRPRR 705

Query: 648  SSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEG 707
              F+TV  L++E+L++LM  L +T+P FVRCI+PN  K  G +E  LVL QLRCNGVLEG
Sbjct: 706  GMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEG 765

Query: 708  IRICRKGFPSRILYADFKQRYKVLNASAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHT 767
            IRICR+GFP+RIL+ +F+QRY++L  +AIP+G F+D K+A EK++ ++++D   Y+ G +
Sbjct: 766  IRICRQGFPNRILFQEFRQRYEILTPNAIPKG-FMDGKQACEKMIQALELDPNLYRVGQS 824

Query: 768  KVFFKAGLLGLLEEMRDDKLAQLITRTQARCRGFLARVEYQRMVERREAIFCIQYNIRSF 827
            K+FF+AG+L  LEE RD K+  +I   QA  RG+LAR  +Q+  +++ A+  +Q N  ++
Sbjct: 825  KIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAAY 884

Query: 828  MNVKHWPWMKLFFKIKPLLKSAETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLL 887
            + ++HW W +LF K+KPLL+    ++ +    +E QK+++   +S  +  EL+ ++  L 
Sbjct: 885  LKLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLE 944

Query: 888  KEKNDLQLQVQAEAEGLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKR 947
            +E+  L  Q++AEAE  A+AEE   +L   K +LE  + E+  R  +EEE + ++  +K+
Sbjct: 945  EERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKK 1004

Query: 948  KLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQE 1007
            +L+    EL+  ++  E    K++ EK  TE K+K   E++  L++  +KL+KE+K L++
Sbjct: 1005 RLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLED 1064

Query: 1008 AHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKL 1067
               +       EE+KV +L K ++K E  + D+E  L +E+K R +LE+ KR+L+G+   
Sbjct: 1065 RLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSE 1124

Query: 1068 AQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEE 1127
             QE +++ +   ++L  +L +KE E+    ++ EDE     QL K ++E QA + E +E+
Sbjct: 1125 LQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQED 1184

Query: 1128 IEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEA 1187
            +E+ER +R KAEKQR DL  ELE +   LE+   +T+AQ E+  KRE E  ++++ LEE 
Sbjct: 1185 LESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEE 1244

Query: 1188 TLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKA 1247
            T  HEA    LR++H  ++ EL EQ++  +R K   EK +  ++ E+ +L + + ++  A
Sbjct: 1245 TRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTA 1304

Query: 1248 KGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQL 1307
            +   E+  R LE QL E++ +  + +R   +   +  R Q E    S  L+E E+   +L
Sbjct: 1305 RQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRL 1364

Query: 1308 SRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRAL 1367
            S+   +   Q+ + +  L+EE +AK AL   +++   +   LREQ EEE  ++    R L
Sbjct: 1365 SKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGREL 1424

Query: 1368 SKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRL 1427
              A  ++++WR + E +A    E  EEA+++ A+  +A  + +         LE+ ++RL
Sbjct: 1425 QTAQAQLSEWRRRQEEEA-GALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRL 1483

Query: 1428 QNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTEL 1487
            Q E++D  +D+E+     + L+KKQR FD++LAE K        E E ++ E R      
Sbjct: 1484 QQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARA 1543

Query: 1488 FKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQ 1547
              +  A EE  +  E L+R+N+ L+ E+  L     + GK +HELE+  +  EQ   +L+
Sbjct: 1544 LSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLR 1603

Query: 1548 AALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTL 1607
            A + E E  L   E   LR+++ +  +K++ +R +  +DE  ++ +R   + +   +   
Sbjct: 1604 AQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVER 1663

Query: 1608 DAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDAL 1667
            D E + R  A+  +KK+EG+L E++ Q+  A +   EA++  R  Q  +K+    +++  
Sbjct: 1664 DEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETR 1723

Query: 1668 RSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNT 1727
             S+E++  Q    E+R   L+AE+  L+  L  ++R+R+ A+Q+  + ++ V   +    
Sbjct: 1724 TSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKA 1783

Query: 1728 SLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLER 1787
            +++  K++LE  + Q++ E+E+    +    ++ +K +     +  EL  E+  SA  E 
Sbjct: 1784 AILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAES 1843

Query: 1788 MKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLR 1847
             ++ +E+ +++L+ RL E +  A    K  I  LE+++ + E ++E E +    + K +R
Sbjct: 1844 GRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVR 1903

Query: 1848 KHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQH 1907
            + E+R+KE+  Q EE+R+   +L+D ++K   +VK  KRQ EEAEE+++   A  R+LQ 
Sbjct: 1904 RAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQR 1963

Query: 1908 ELEEAEERADIAESQVNKLRVKSR 1931
            ELE+  E A+    +V  LR + R
Sbjct: 1964 ELEDVTESAESMNREVTTLRNRLR 1987



 Score =  224 bits (572), Expect = 5e-58
 Identities = 195/932 (20%), Positives = 421/932 (45%), Gaps = 48/932 (5%)

Query: 859  KEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCD------ 912
            ++E +K+K  L   + +  EL+E+MV   +   +L+ Q+  + E L  A  R +      
Sbjct: 1108 RQELEKLKRRL---DGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGAR 1164

Query: 913  -QLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVE 971
             QL+K+  + +A + E  E  E E     +   ++R L +E   L+ +++D   TL    
Sbjct: 1165 AQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELED---TLDSTN 1221

Query: 972  KEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVN----TLT 1027
             ++     + + +TE    L+E         + L++ H Q L +L  + ++         
Sbjct: 1222 AQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWE 1281

Query: 1028 KAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLK 1087
            K ++ LE +V +L   L   +  R + E+ +R+LE  L+  Q    D E  + +  EKL+
Sbjct: 1282 KTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQ 1341

Query: 1088 KKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSR 1147
            + + E+ N+   + + ++  I+L K++   +A++ + +E ++ E  ++     +   +  
Sbjct: 1342 RAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEA 1401

Query: 1148 ELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADS-- 1205
            E   + E+LEE   A        +  +A+  + RR  EE     EA     R+   ++  
Sbjct: 1402 EAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEA 1461

Query: 1206 ----VAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQ 1261
                +AE  E +D L+R +++L++E  +  M+++     V T+ K +   +++    E++
Sbjct: 1462 LTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLA--EEK 1519

Query: 1262 LSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEEL 1321
             + L++ EE ++       A+    +  +   +R L+E++    +L R  +A   ++E L
Sbjct: 1520 AAVLRAVEERERA-----EAEGREREARALSLTRALEEEQEAREELERQNRALRAELEAL 1574

Query: 1322 KRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKY 1381
                ++  K+ + L  A + +    + LR Q  E ++     + A  +    V   +T++
Sbjct: 1575 LSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQH 1634

Query: 1382 ETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERT 1441
            E D   R E  EE +++LA++L+ AE   +    +       +++L+ E+E+L   +   
Sbjct: 1635 ERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASA 1694

Query: 1442 NAACAALDKKQRNFDKILAEWKQKCEETHAELEA-------SQKEARSLGTELFKIKNAY 1494
                    K+ R     + E  ++ EET    E        S+K  + L  E+ +++   
Sbjct: 1695 GQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQ--- 1751

Query: 1495 EESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAE 1554
                ++L    R  +  QQ+  ++ +++A G      + + K+Q+E    +L+  LEE +
Sbjct: 1752 ----EELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQ 1807

Query: 1555 ASLEHEEGKILRIQLELNQVKSEV--DRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIR 1612
            ++ E    +  ++ L++  + +E+  +R  + K E   Q     I+ +       DA  R
Sbjct: 1808 SNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGAR 1867

Query: 1613 SRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQED 1672
            +R+        +E  L + E QL    R    + +  R  +  LK+  + +++  R  + 
Sbjct: 1868 ARHKMTIAA--LESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQ 1925

Query: 1673 LKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINT 1732
            L++QL     R   L+ ++EE      + +  R+  ++EL D +E  + ++ + T+L N 
Sbjct: 1926 LRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNR 1985

Query: 1733 KKKLETDISQMQGEMEDILQEARNAEEKAKKA 1764
             ++     +         L+E   ++E+A++A
Sbjct: 1986 LRRGPLTFTTRTVRQVFRLEEGVASDEEAEEA 2017



 Score =  171 bits (434), Expect = 5e-42
 Identities = 178/881 (20%), Positives = 381/881 (43%), Gaps = 83/881 (9%)

Query: 1099 KIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEE 1158
            +++  Q L  Q  +++ ELQ R+ +LEEE    RA  A+  +  ++L  E EE   RL  
Sbjct: 918  ELQKVQELQQQSAREVGELQGRVAQLEEE----RARLAEQLRAEAELCAEAEETRGRLAA 973

Query: 1159 AGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQR 1218
                    +   + R  E ++  R ++           T +K+    + EL   ++  + 
Sbjct: 974  RKQELELVVSELEARVGEEEECSRQMQ-----------TEKKRLQQHIQELEAHLEAEEG 1022

Query: 1219 VKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLIND 1278
             +QKL+ EK   + ++     ++  +      L K  + LED+L+E  S+  E++  +  
Sbjct: 1023 ARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKS 1082

Query: 1279 LTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHA 1338
            L   R + +    +   +L ++E    +L + K+    +  EL+ Q+ E+ +    L   
Sbjct: 1083 LNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQ 1142

Query: 1339 LQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKK 1398
            L     +      + E+E  ++A+L ++L +A   +A+ +   E++ + RT+  E+ ++ 
Sbjct: 1143 LGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKA-EKQRRD 1201

Query: 1399 LAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVER-TNAACAALDKKQRNFDK 1457
            L + L+A    +E       + ++ + + + EV +L   +E  T    AA+ + ++   +
Sbjct: 1202 LGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQ 1261

Query: 1458 ILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISD 1517
             L E  ++ E+      A +K   +L  E+ +++      L  L+T ++E +  ++    
Sbjct: 1262 ALGELAEQLEQARRGKGAWEKTRLALEAEVSELR----AELSSLQTARQEGEQRRRR--- 1314

Query: 1518 LTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSE 1577
            L  Q+ E   R  + E+ + +  ++    QA LE    +L   E K +R+  EL+  +++
Sbjct: 1315 LELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQ 1374

Query: 1578 VDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNH 1637
            +                         Q  L  E R++       + ME +   +  QL  
Sbjct: 1375 L----------------------HDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEE 1412

Query: 1638 ANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRAT 1697
                   A R  +  Q  L + +   ++   + E  +E      R A  L   + E   T
Sbjct: 1413 EAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTET 1472

Query: 1698 LEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNA 1757
            +++ ER R+  +QEL DA+  ++      ++L   ++K +  +++ +  +   ++E   A
Sbjct: 1473 VDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERA 1532

Query: 1758 EEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAE------QLAL 1811
            E + ++    A  +   L++EQ+    LER  + +   ++ L    D+        + A 
Sbjct: 1533 EAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERAC 1592

Query: 1812 KGGKKQIQKLEARVRELEGEV---ESEQKRNAEAVKGLR-KHER---------------- 1851
            +  ++    L A+V ELE E+   E  + R    V+ L+ +HER                
Sbjct: 1593 RVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQL 1652

Query: 1852 --RVKELTYQTEEDRKNIL-------RLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKF 1902
              ++++   + +E+RK          +L+  +++L+A++ S  +  EEA +Q     A+ 
Sbjct: 1653 AKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQM 1712

Query: 1903 RKLQHELEEAEERAD--IAESQVNKLRVKSREVHTKVISEE 1941
            ++L  E+EE     +   ++++ ++ R+K  E     + EE
Sbjct: 1713 KELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEE 1753



 Score =  117 bits (292), Expect = 1e-25
 Identities = 130/642 (20%), Positives = 262/642 (40%), Gaps = 49/642 (7%)

Query: 1339 LQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKK 1398
            LQ+   +   ++E  ++      ELQ  +++   E A+   +   +A +   E EE + +
Sbjct: 912  LQARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEA-ELCAEAEETRGR 970

Query: 1399 LAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALD--KKQRNFD 1456
            LA R Q  E  V  + A+    E+  +++Q E + L   ++   A   A +  +++   +
Sbjct: 971  LAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLE 1030

Query: 1457 KILAEWKQKCEETHAELEASQ-----KEARSLGTELFKIKNAYEESLDQLETLKRENKNL 1511
            K+  E K K  E    L   Q     KE + L   L +  +   E  +++++L +     
Sbjct: 1031 KVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKY 1090

Query: 1512 QQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLEL 1571
            +  I+D+ +++ +  K   ELEK+K++++ E  ELQ  + E +   E    ++ R + EL
Sbjct: 1091 EATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEEL 1150

Query: 1572 NQVKS-----------------EVDRKIAEKDEEID----------QLKRNHIRIVESMQ 1604
                +                 E    +AE  E+++          + +R+    +E+++
Sbjct: 1151 QAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALR 1210

Query: 1605 STLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLD 1664
              L+  + S N    L+ K E ++ E++  L    R+   A++  R   G        L 
Sbjct: 1211 GELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQA------LG 1264

Query: 1665 DALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHT 1724
            +     E  +      E+    L+AE+ ELRA L   + +R+  EQ       ++Q +  
Sbjct: 1265 ELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQG 1324

Query: 1725 QNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAH 1784
            +       + +    + + Q E+E++      AE K  +   + +    +L   Q+    
Sbjct: 1325 RAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQE 1384

Query: 1785 LERMK-------KNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQK 1837
              R K       + ME     L+ +L+E E  A +   +++Q  +A++ E     E E  
Sbjct: 1385 ETRAKLALGSRVRAMEAEAAGLREQLEE-EAAARERAGRELQTAQAQLSEWRRRQEEEAG 1443

Query: 1838 RNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNT 1897
                  +  R+  R  + LT +  E  + + RL+    +LQ ++       E+  +  +T
Sbjct: 1444 ALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVST 1503

Query: 1898 NLAKFRKLQHELEEAEERADIAESQVNKLRVKSREVHTKVIS 1939
               K RK    L E +     A  +  +   + RE   + +S
Sbjct: 1504 LEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALS 1545


>gi|153945715 myosin VC [Homo sapiens]
          Length = 1742

 Score =  608 bits (1569), Expect = e-173
 Identities = 454/1440 (31%), Positives = 718/1440 (49%), Gaps = 107/1440 (7%)

Query: 38   VFVAEPKESFVKGTIQS--REGGKVT-VKTEGGATL--TVKDDQVFPM-NPPKYDKIEDM 91
            V++ +P+E +    I    R G KV  +  E G  L  +V  + + P+ NP       D+
Sbjct: 13   VWIPDPEEVWKSAEIAKDYRVGDKVLRLLLEDGTELDYSVNPESLPPLRNPDILVGENDL 72

Query: 92   AMMTHLHEPAVLYNLKERYA-AWMIYTYSGLFCVTVNPYKWLPVYKPEVVTAYRGKKRQE 150
              +++LHEPAVL+NL+ R+A + +IYTYSG+  V +NPYK LP+Y   ++ AY G+   +
Sbjct: 73   TALSYLHEPAVLHNLRIRFAESKLIYTYSGIILVAMNPYKQLPIYGDAIIHAYSGQNMGD 132

Query: 151  APPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKEEI 210
              PHIF++++ AY+ M  +  NQSI+++GESGAGKTV+ +  ++YFAT++ +G       
Sbjct: 133  MDPHIFAVAEEAYKQMARNNRNQSIIVSGESGAGKTVSARYAMRYFATVSKSGSNAH--- 189

Query: 211  TSGKIQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYL 270
                    +ED+++++NP+ EA GNAKT RNDNSSRFGK+  I F    ++  A++ TYL
Sbjct: 190  --------VEDKVLASNPITEAVGNAKTTRNDNSSRFGKYTEISFDEQNQIIGANMSTYL 241

Query: 271  LEKSRVVFQLKAERSYHIFYQI-TSNKKPELIEMLLITTNPYDYPFVSQGEISVASIDDQ 329
            LEKSRVVFQ + ER+YHIFYQ+  S ++ E   + L +   ++Y  +  G   +  ++D+
Sbjct: 242  LEKSRVVFQSENERNYHIFYQLCASAQQSEFKHLKLGSAEEFNYTRMG-GNTVIEGVNDR 300

Query: 330  EELMATDSAIDILGFTNEEKVSIYKLTGAVMHYGNLKFKQKQREEQAEPDGTEVADKAAY 389
             E++ T     +LGF  + ++ ++K+  A++H GN++      E  +  +          
Sbjct: 301  AEMVETQKTFTLLGFKEDFQMDVFKILAAILHLGNVQITAVGNERSSVSEDDSHLKVFCE 360

Query: 390  LQSLNSADLLKALCYPRVKVGNEYVTKGQTVEQVSNAVGALAKAVYEKMFLWMVARINQQ 449
            L  L S  + + LC  ++   +E V K  T  Q  NA  ALAK +Y  +F ++V RINQ 
Sbjct: 361  LLGLESGRVAQWLCNRKIVTSSETVVKPMTRPQAVNARDALAKKIYAHLFDFIVERINQA 420

Query: 450  LDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGI 509
            L     +  FIGVLDI GFE FD NS EQ CIN+ NEKLQQ FN H+F LEQEEY KE I
Sbjct: 421  LQFSGKQHTFIGVLDIYGFETFDVNSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEDI 480

Query: 510  EWTFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLYDQHLGKSANFQKP 569
             WT IDF  D    I+LIE  MGI  +L+EEC+ P  TD ++  KLY+  + ++  F+KP
Sbjct: 481  PWTLIDF-YDNQPVIDLIEAKMGILELLDEECLLPHGTDENWLQKLYNNFVNRNPLFEKP 539

Query: 570  KVVKGKAEAHFALIHYAGVVDYNITGWLEKNKDPLNETVVGLYQKSAMKTLAQLFSGAQT 629
            ++    +   F + H+A  V+Y   G+LEKN+D + + +V + + S     A  F    T
Sbjct: 540  RM----SNTSFVIQHFADKVEYKCEGFLEKNRDTVYDMLVEILRASKFHLCANFFQENPT 595

Query: 630  AEGEGAG----GGAKKGGKKKGSSFQ-TVSALFRENLNKLMTNLRSTHPHFVRCIIPNET 684
                         AK+  K     F+ TV + FR +L  LM  L +T PH+VRCI PN+ 
Sbjct: 596  PPSPFGSMITVKSAKQVIKPNSKHFRTTVGSKFRSSLYLLMETLNATTPHYVRCIKPNDE 655

Query: 685  KTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQFIDS 744
            K P   + + ++ QLR  GVLE IRI  + +PSR  Y +F  RY +L      E  F D 
Sbjct: 656  KLPFEFDSKRIVQQLRACGVLETIRISAQSYPSRWTYIEFYSRYGILMTK--QELSFSDK 713

Query: 745  KKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDDKLAQLITRTQARCRGFLAR 804
            K+  + +L  +  D  QY+FG TK+FF+AG +  LE++R DKL Q     Q   RG+L R
Sbjct: 714  KEVCKVVLHRLIQDSNQYQFGKTKIFFRAGQVAYLEKLRLDKLRQSCVMVQKHMRGWLQR 773

Query: 805  VEYQRMVERREAIFCIQYNIRSFMNVK--------HWPWMKLFFKIK---PLLKSAETEK 853
             ++ R  ERR A+   QY  R    V+           W  +  +      L++S     
Sbjct: 774  KKFLR--ERRAALIIQQY-FRGQQTVRKAITAVALKEAWAAIIIQKHCRGYLVRSLYQLI 830

Query: 854  EMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCDQ 913
             MAT+    Q            RK LEE    +        LQ  A A  LA    +  +
Sbjct: 831  RMATI--TMQAYSRGFLARRRYRKMLEEHKAVI--------LQKYARA-WLARRRFQSIR 879

Query: 914  LIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKE 973
                 IQL  +++ + ++ ED+ + N  L  K   L    +   + I  LE  L K    
Sbjct: 880  RFVLNIQLTYRVQRLQKKLEDQNKENHGLVEKLTSLAALRAGDVEKIQKLEAELEKAATH 939

Query: 974  KHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKL 1033
            +   E K K   +    ++E +AKL K    L+   +Q    LQ + +++      K K+
Sbjct: 940  RRNYEEKGKRYRD---AVEEKLAKLQKHNSELETQKEQIQLKLQEKTEEL------KEKM 990

Query: 1034 EQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEI 1093
            +     L   +++E++ RM LE          K  +    D E + Q L E++K  + E 
Sbjct: 991  DNLTKQLFDDVQKEERQRMLLE----------KSFELKTQDYEKQIQSLKEEIKALKDEK 1040

Query: 1094 SNLQSKIEDEQALGIQLQKKIKELQAR---IEELEEEIEAERASRAKAEK----QRSDLS 1146
              LQ  +E E      L+ ++  L  +   I E E+EIE  +A +   EK    Q+ ++ 
Sbjct: 1041 MQLQHLVEGEHVTSDGLKAEVARLSKQVKTISEFEKEIELLQAQKIDVEKHVQSQKREMR 1100

Query: 1147 RELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSV 1206
             ++ EI+++L E     S  IE  + R +       DLE      E   A    K A  V
Sbjct: 1101 EKMSEITKQLLE-----SYDIEDVRSRLSV-----EDLEHLNEDGELWFAYEGLKKATRV 1150

Query: 1207 AELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELK 1266
             E      + Q  K   EKE   +  ++  L+  +  + K       +  ++  +++ L 
Sbjct: 1151 LE-----SHFQSQKDCYEKEIEALNFKVVHLSQEINHLQKLFREENDINESIRHEVTRLT 1205

Query: 1267 SKE---EEQQRLINDLTAQRGRLQTESGEFSRQLDEK-EALVSQLSRGKQAFTQQIEELK 1322
            S+     + ++ I++L  Q+  L+    E + ++  K E L +QL R ++    Q + L+
Sbjct: 1206 SENMMIPDFKQQISELEKQKQDLEIRLNEQAEKMKGKLEELSNQLHRSQEEEGTQRKALE 1265

Query: 1323 RQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYE 1382
             Q E   K K  L   +Q  +   D L++Q+E E E K   ++  S+   E      + E
Sbjct: 1266 AQNEIHTKEKEKLIDKIQEMQEASDHLKKQFETESEVKCNFRQEASRLTLENRD--LEEE 1323

Query: 1383 TDAIQRT-EELEEAKKKLAQRLQAAEEHVEAVNAK--CASLEKTKQRLQNEVEDLMLDVE 1439
             D   R  ++L++  K L++ +  A +   +   K     L+  ++     +++L+LD++
Sbjct: 1324 LDMKDRVIKKLQDQVKTLSKTIGKANDVHSSSGPKEYLGMLQYKREDEAKLIQNLILDLK 1383



 Score = 77.8 bits (190), Expect = 1e-13
 Identities = 99/525 (18%), Positives = 222/525 (42%), Gaps = 45/525 (8%)

Query: 1315 TQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEV 1374
            T +++ L+++LE++ K  + L   L S      L     E+ Q+ +AEL++A        
Sbjct: 888  TYRVQRLQKKLEDQNKENHGLVEKLTSL---AALRAGDVEKIQKLEAELEKA-------- 936

Query: 1375 AQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCAS-LEKTKQRLQNEVED 1433
            A  R  YE    +  + +EE   KL +     E   E +  K     E+ K+++ N  + 
Sbjct: 937  ATHRRNYEEKGKRYRDAVEEKLAKLQKHNSELETQKEQIQLKLQEKTEELKEKMDNLTKQ 996

Query: 1434 LMLDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNA 1493
            L  DV++       L+K           ++ K ++   ++++ ++E ++L  E  ++++ 
Sbjct: 997  LFDDVQKEERQRMLLEKS----------FELKTQDYEKQIQSLKEEIKALKDEKMQLQHL 1046

Query: 1494 YEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEA 1553
             E      + LK E   L +++           K I E EK  + ++ +K +++  ++  
Sbjct: 1047 VEGEHVTSDGLKAEVARLSKQV-----------KTISEFEKEIELLQAQKIDVEKHVQSQ 1095

Query: 1554 EASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQST--LDAEI 1611
            +  +  +  +I +  LE   ++    R   E  E +++            ++T  L++  
Sbjct: 1096 KREMREKMSEITKQLLESYDIEDVRSRLSVEDLEHLNEDGELWFAYEGLKKATRVLESHF 1155

Query: 1612 RSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQE 1671
            +S+ D    +K++E  LN   + L+       +  R   +    ++     L        
Sbjct: 1156 QSQKDCY--EKEIEA-LNFKVVHLSQEINHLQKLFREENDINESIRHEVTRLTSENMMIP 1212

Query: 1672 DLKEQLAMVERRANLLQAEI----EELRATLEQTERSRKIAEQELLDASERVQLLHTQNT 1727
            D K+Q++ +E++   L+  +    E+++  LE+       +++E  + ++R + L  QN 
Sbjct: 1213 DFKQQISELEKQKQDLEIRLNEQAEKMKGKLEELSNQLHRSQEE--EGTQR-KALEAQNE 1269

Query: 1728 SLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLER 1787
                 K+KL   I +MQ   + + ++     E       +A+ +  E +  ++     +R
Sbjct: 1270 IHTKEKEKLIDKIQEMQEASDHLKKQFETESEVKCNFRQEASRLTLENRDLEEELDMKDR 1329

Query: 1788 MKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEV 1832
            + K ++  VK L   + +A  +    G K+   +    RE E ++
Sbjct: 1330 VIKKLQDQVKTLSKTIGKANDVHSSSGPKEYLGMLQYKREDEAKL 1374



 Score = 70.5 bits (171), Expect = 2e-11
 Identities = 97/511 (18%), Positives = 216/511 (42%), Gaps = 57/511 (11%)

Query: 1452 QRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAY--EESLDQLETLKRENK 1509
            +R + K+L E K    + +A    +++  +S+   +  I+  Y  +    +LE   +EN 
Sbjct: 847  RRRYRKMLEEHKAVILQKYARAWLARRRFQSIRRFVLNIQLTYRVQRLQKKLEDQNKENH 906

Query: 1510 NLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQL 1569
             L ++++ L    A   ++I +LE   ++    +   +   +    ++E +  K+ +   
Sbjct: 907  GLVEKLTSLAALRAGDVEKIQKLEAELEKAATHRRNYEEKGKRYRDAVEEKLAKLQKHNS 966

Query: 1570 ELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLN 1629
            EL   K ++  K+ EK EE+ +   N   + + +   +  E R R   + L+K  E    
Sbjct: 967  ELETQKEQIQLKLQEKTEELKEKMDN---LTKQLFDDVQKEERQR---MLLEKSFELKTQ 1020

Query: 1630 EMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQ----EDLKEQLAMVERRAN 1685
            + E Q+           ++ +     LKD ++ L   +  +    + LK ++A + ++  
Sbjct: 1021 DYEKQI-----------QSLKEEIKALKDEKMQLQHLVEGEHVTSDGLKAEVARLSKQVK 1069

Query: 1686 LL---QAEIEELRATLEQTERSRKIAEQELLDASERV--QLLHTQNTSLINTKKKLETDI 1740
             +   + EIE L+A     E+  +  ++E+ +    +  QLL + +   + ++  +E D+
Sbjct: 1070 TISEFEKEIELLQAQKIDVEKHVQSQKREMREKMSEITKQLLESYDIEDVRSRLSVE-DL 1128

Query: 1741 SQMQGE----------------MEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAH 1784
              +  +                +E   Q  ++  EK  +A+    +    L +E +    
Sbjct: 1129 EHLNEDGELWFAYEGLKKATRVLESHFQSQKDCYEKEIEALNFKVV---HLSQEINHLQK 1185

Query: 1785 LERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVK 1844
            L R + ++ ++++    RL  +E + +   K+QI +LE + ++LE  +  + ++    ++
Sbjct: 1186 LFREENDINESIRHEVTRLT-SENMMIPDFKQQISELEKQKQDLEIRLNEQAEKMKGKLE 1244

Query: 1845 GLRKHERRVKE--------LTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSN 1896
             L     R +E        L  Q E   K   +L D + ++Q      K+Q E   E   
Sbjct: 1245 ELSNQLHRSQEEEGTQRKALEAQNEIHTKEKEKLIDKIQEMQEASDHLKKQFETESEVKC 1304

Query: 1897 TNLAKFRKLQHELEEAEERADIAESQVNKLR 1927
                +  +L  E  + EE  D+ +  + KL+
Sbjct: 1305 NFRQEASRLTLENRDLEEELDMKDRVIKKLQ 1335



 Score = 34.7 bits (78), Expect = 0.93
 Identities = 27/118 (22%), Positives = 55/118 (46%), Gaps = 13/118 (11%)

Query: 1820 KLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQA 1879
            +L  RV+ L+ ++E + K N   V+       ++  L      D + I +L+  ++K   
Sbjct: 886  QLTYRVQRLQKKLEDQNKENHGLVE-------KLTSLAALRAGDVEKIQKLEAELEKAAT 938

Query: 1880 KVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAESQVNKLRVKSREVHTKV 1937
              ++Y+ + +   +     LAK +K   ELE  +E+  +      KL+ K+ E+  K+
Sbjct: 939  HRRNYEEKGKRYRDAVEEKLAKLQKHNSELETQKEQIQL------KLQEKTEELKEKM 990


>gi|215982794 myosin VA isoform 2 [Homo sapiens]
          Length = 1828

 Score =  597 bits (1539), Expect = e-170
 Identities = 456/1569 (29%), Positives = 758/1569 (48%), Gaps = 208/1569 (13%)

Query: 90   DMAMMTHLHEPAVLYNLKERYA-AWMIYTYSGLFCVTVNPYKWLPVYKPEVVTAYRGKKR 148
            D+  +++LHEPAVL+NL+ R+  + +IYTY G+  V +NPY+ LP+Y  +++ AY G+  
Sbjct: 73   DLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAYSGQNM 132

Query: 149  QEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKE 208
             +  PHIF++++ AY+ M  D  NQSI+++GESGAGKTV+ K  ++YFAT++ +      
Sbjct: 133  GDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGSAS---- 188

Query: 209  EITSGKIQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIET 268
                   +  +E++++++NP++E+ GNAKT RNDNSSRFGK+I I F    ++  A++ T
Sbjct: 189  -------EANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMRT 241

Query: 269  YLLEKSRVVFQLKAERSYHIFYQITSNKKPELIEMLLITTNPYDYPFVSQGEISVAS-ID 327
            YLLEKSRVVFQ + ER+YHIFYQ+ ++ K    +ML +  N  ++ +  QG   V   +D
Sbjct: 242  YLLEKSRVVFQAEEERNYHIFYQLCASAKLPEFKMLRLG-NADNFNYTKQGGSPVIEGVD 300

Query: 328  DQEELMATDSAIDILGFTNEEKVSIYKLTGAVMHYGNLKFKQKQREEQAEPDGTEVADKA 387
            D +E+  T  A  +LG +   ++ I+++   ++H GN+ F  +  +    P   E     
Sbjct: 301  DAKEMAHTRQACTLLGISESHQMGIFRILAGILHLGNVGFTSRDADSCTIPPKHEPLCIF 360

Query: 388  AYLQSLNSADLLKALCYPRVKVGNEYVTKGQTVEQVSNAVGALAKAVYEKMFLWMVARIN 447
              L  ++  ++   LC+ ++    E   K  +  Q +NA  ALAK +Y K+F W+V  +N
Sbjct: 361  CDLMGVDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVDNVN 420

Query: 448  QQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKE 507
            Q L +   +  FIGVLDI GFE F+ NS EQ CIN+ NEKLQQ FN H+F LEQEEY KE
Sbjct: 421  QALHSAVKQHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKE 480

Query: 508  GIEWTFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLYDQHLGKSANFQ 567
             I WT IDF  D   CI LIE  +GI  +L+EEC  PK TD ++  KLY+ HL K A F+
Sbjct: 481  QIPWTLIDF-YDNQPCINLIESKLGILDLLDEECKMPKGTDDTWAQKLYNTHLNKCALFE 539

Query: 568  KPKVVKGKAEAHFALIHYAGVVDYNITGWLEKNKDPLNETVVGLYQKSAMKTLAQLF--- 624
            KP++    +   F + H+A  V+Y   G+LEKNKD + E  + + + S  K L +LF   
Sbjct: 540  KPRL----SNKAFIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLPELFQDD 595

Query: 625  -----------SGAQTAEGEGAGGGAKKGGKKKGSSFQTVSALFRENLNKLMTNLRSTHP 673
                       SG        A     + G+      +TV   FR +L+ LM  L +T P
Sbjct: 596  EKAISPTSATSSGRTPLTRTPAKPTKGRPGQMAKEHKKTVGHQFRNSLHLLMETLNATTP 655

Query: 674  HFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNA 733
            H+VRCI PN+ K P   + +  + QLR  GVLE IRI   GFPSR  Y +F  RY+VL  
Sbjct: 656  HYVRCIKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRVLMK 715

Query: 734  SAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDDKLAQLITR 793
                +    D K+  + +L  + +D  +Y+FG TK+FF+AG +  LE++R DKL     R
Sbjct: 716  Q---KDVLSDRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKLRADKLRAACIR 772

Query: 794  TQARCRGFLARVEYQRMVERREAIFCIQYNIRSFM---------NVKHWPWMKLFFKIKP 844
             Q   RG+L R +Y RM   R+A   +Q  +R +            K    ++ ++++  
Sbjct: 773  IQKTIRGWLLRKKYLRM---RKAAITMQRYVRGYQARCYAKFLRRTKAATIIQKYWRMYV 829

Query: 845  LLKSAETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKE----------KNDL- 893
            + +  +  +    + + +  ++  LA++  ++   E K V + K           K  + 
Sbjct: 830  VRRRYKIRRAATIVLQSY--LRGFLARNRYRKILREHKAVIIQKRVRGWLARTHYKRSMH 887

Query: 894  ----------QLQVQAEAEGLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELT 943
                      ++  + E + L       ++  K  I +E KI ++  + +++ +    L 
Sbjct: 888  AIIYLQCCFRRMMAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLV 947

Query: 944  AKKRKLE----DECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLT 999
             K   LE     E  +L+ D++ L+L+    E+E      +V +L EE+A L + + +  
Sbjct: 948  EKLTNLEGIYNSETEKLRSDLERLQLS----EEEAKVATGRVLSLQEEIAKLRKDLEQTR 1003

Query: 1000 KEKKALQE---AHQQTLDDLQAEEDKVNTLTKAK-----IKLEQQVDDLEGSLEQE---- 1047
             EKK ++E    ++Q  + L +   + NTL K +      ++ QQ  ++  ++E++    
Sbjct: 1004 SEKKCIEEHADRYKQETEQLVSNLKEENTLLKQEKEALNHRIVQQAKEMTETMEKKLVEE 1063

Query: 1048 -KKLRMDL--ERAK-RKLEGDLKLAQESIMDIENE-------------KQQLDEKLKKKE 1090
             K+L +DL  ER + + L  +    +E   D++ E             +        + E
Sbjct: 1064 TKQLELDLNDERLRYQNLLNEFSRLEERYDDLKEEMTLMVHVPKPGHKRTDSTHSSNESE 1123

Query: 1091 FEISNLQSKIED---------------EQALGIQLQKKIKELQARIEELEEEIEAER--- 1132
            +  S+  +++ED               + +L ++LQK++ EL+   + +++E++ +    
Sbjct: 1124 YIFSSEIAEMEDIPSRTEEPSEKKVPLDMSLFLKLQKRVTELEQEKQVMQDELDRKEEQV 1183

Query: 1133 -ASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDL-EEATLQ 1190
              S+AK E++      ELE  S + +E           NKK + E  ++R+ L E++  +
Sbjct: 1184 LRSKAKEEERPQIRGAELEYESLKRQELESE-------NKKLKNELNELRKALSEKSAPE 1236

Query: 1191 HEATAATLRKKHADSVAELGEQID---------NLQRVKQKLEKEKSEMKMEIDDLASNV 1241
              A  A   +   + +  + E++D           Q V QK   +  + K  + D    +
Sbjct: 1237 VTAPGAPAYRVLMEQLTSVSEELDVRKEEVLILRSQLVSQKEAIQPKDDKNTMTDSTILL 1296

Query: 1242 ETVSKAKG---------NLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGE 1292
            E V K K           L++  R LE QL   K   E      N+  A RG +Q+   E
Sbjct: 1297 EDVQKMKDKGEIAQAYIGLKETNRLLESQLQSQKRSHE------NEAEALRGEIQSLKEE 1350

Query: 1293 FSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQ 1352
             +RQ                   QQ+     QL  E + + +L H +    ++   L EQ
Sbjct: 1351 NNRQ-------------------QQLLAQNLQLPPEARIEASLQHEITRLTNENLDLMEQ 1391

Query: 1353 YEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEA 1412
             E++ ++  +L++ L     ++                ELE  + +     Q  +E +  
Sbjct: 1392 LEKQDKTVRKLKKQLKVFAKKIG---------------ELEVGQMENISPGQIIDEPIRP 1436

Query: 1413 VNAK------CASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKC 1466
            VN           LE  K+  Q  V++L+L+++    A         N    L  +    
Sbjct: 1437 VNIPRKEKDFQGMLEYKKEDEQKLVKNLILELKPRGVAV--------NLIPGLPAYILFM 1488

Query: 1467 EETHAELEASQKEARSLGTE-LFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEG 1525
               HA+     ++ RSL T  +  IK   ++  D  ET+     N  + +  L +   E 
Sbjct: 1489 CVRHADYLNDDQKVRSLLTSTINSIKKVLKKRGDDFETVSFWLSNTCRFLHCLKQYSGEE 1548

Query: 1526 GKRIHELEK 1534
            G   H   +
Sbjct: 1549 GFMKHNTSR 1557



 Score = 57.4 bits (137), Expect = 1e-07
 Identities = 106/495 (21%), Positives = 215/495 (43%), Gaps = 93/495 (18%)

Query: 1472 ELEASQKEARSLGTELFKIKNAYEESLDQLET-LKRENKNLQQEISDLTEQIAEGGKRIH 1530
            EL+  + EARS+     K+    E  + QL+  +  +NK+ +  +  LT      G    
Sbjct: 904  ELKKLKIEARSV-ERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNL---EGIYNS 959

Query: 1531 ELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEK---DE 1587
            E EK++  +E+    LQ + EEA+ +     G++L +Q E+ +++ ++++  +EK   +E
Sbjct: 960  ETEKLRSDLER----LQLSEEEAKVAT----GRVLSLQEEIAKLRKDLEQTRSEKKCIEE 1011

Query: 1588 EIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALR 1647
              D+ K+   ++V ++          + +   LK++ E         LNH     A+ + 
Sbjct: 1012 HADRYKQETEQLVSNL----------KEENTLLKQEKEA--------LNHRIVQQAKEMT 1053

Query: 1648 NYRNTQGILKDTQIHLD---DALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERS 1704
                 + + +  Q+ LD   + LR Q  L E   + ER  +L     EE+   +   +  
Sbjct: 1054 ETMEKKLVEETKQLELDLNDERLRYQNLLNEFSRLEERYDDLK----EEMTLMVHVPKPG 1109

Query: 1705 RKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKA 1764
             K           R    H+ N S        E   S    EMEDI   +R  E   KK 
Sbjct: 1110 HK-----------RTDSTHSSNES--------EYIFSSEIAEMEDI--PSRTEEPSEKKV 1148

Query: 1765 ITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEAR 1824
              D ++  +           L++    +EQ  + +Q  LD  E+  L+   K+ ++ + R
Sbjct: 1149 PLDMSLFLK-----------LQKRVTELEQEKQVMQDELDRKEEQVLRSKAKEEERPQIR 1197

Query: 1825 VRELE------GEVESEQKRNAEAVKGLRK--HERRVKELTYQTEEDRKNIL-RLQDLVD 1875
              ELE       E+ESE K+    +  LRK   E+   E+T       + ++ +L  + +
Sbjct: 1198 GAELEYESLKRQELESENKKLKNELNELRKALSEKSAPEVTAPGAPAYRVLMEQLTSVSE 1257

Query: 1876 KLQAKVKSY---------KRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAESQVNKL 1926
            +L  + +           +++A + ++  NT +     L  ++++ +++ +IA++ +  L
Sbjct: 1258 ELDVRKEEVLILRSQLVSQKEAIQPKDDKNT-MTDSTILLEDVQKMKDKGEIAQAYIG-L 1315

Query: 1927 RVKSREVHTKVISEE 1941
            +  +R + +++ S++
Sbjct: 1316 KETNRLLESQLQSQK 1330


>gi|215982791 myosin VA isoform 1 [Homo sapiens]
          Length = 1855

 Score =  594 bits (1532), Expect = e-169
 Identities = 435/1453 (29%), Positives = 731/1453 (50%), Gaps = 164/1453 (11%)

Query: 90   DMAMMTHLHEPAVLYNLKERYA-AWMIYTYSGLFCVTVNPYKWLPVYKPEVVTAYRGKKR 148
            D+  +++LHEPAVL+NL+ R+  + +IYTY G+  V +NPY+ LP+Y  +++ AY G+  
Sbjct: 73   DLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAYSGQNM 132

Query: 149  QEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKE 208
             +  PHIF++++ AY+ M  D  NQSI+++GESGAGKTV+ K  ++YFAT++ +      
Sbjct: 133  GDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGSAS---- 188

Query: 209  EITSGKIQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIET 268
                   +  +E++++++NP++E+ GNAKT RNDNSSRFGK+I I F    ++  A++ T
Sbjct: 189  -------EANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMRT 241

Query: 269  YLLEKSRVVFQLKAERSYHIFYQITSNKKPELIEMLLITTNPYDYPFVSQGEISVAS-ID 327
            YLLEKSRVVFQ + ER+YHIFYQ+ ++ K    +ML +  N  ++ +  QG   V   +D
Sbjct: 242  YLLEKSRVVFQAEEERNYHIFYQLCASAKLPEFKMLRLG-NADNFNYTKQGGSPVIEGVD 300

Query: 328  DQEELMATDSAIDILGFTNEEKVSIYKLTGAVMHYGNLKFKQKQREEQAEPDGTEVADKA 387
            D +E+  T  A  +LG +   ++ I+++   ++H GN+ F  +  +    P   E     
Sbjct: 301  DAKEMAHTRQACTLLGISESHQMGIFRILAGILHLGNVGFTSRDADSCTIPPKHEPLCIF 360

Query: 388  AYLQSLNSADLLKALCYPRVKVGNEYVTKGQTVEQVSNAVGALAKAVYEKMFLWMVARIN 447
              L  ++  ++   LC+ ++    E   K  +  Q +NA  ALAK +Y K+F W+V  +N
Sbjct: 361  CDLMGVDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVDNVN 420

Query: 448  QQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKE 507
            Q L +   +  FIGVLDI GFE F+ NS EQ CIN+ NEKLQQ FN H+F LEQEEY KE
Sbjct: 421  QALHSAVKQHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKE 480

Query: 508  GIEWTFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLYDQHLGKSANFQ 567
             I WT IDF  D   CI LIE  +GI  +L+EEC  PK TD ++  KLY+ HL K A F+
Sbjct: 481  QIPWTLIDF-YDNQPCINLIESKLGILDLLDEECKMPKGTDDTWAQKLYNTHLNKCALFE 539

Query: 568  KPKVVKGKAEAHFALIHYAGVVDYNITGWLEKNKDPLNETVVGLYQKSAMKTLAQLF--- 624
            KP++    +   F + H+A  V+Y   G+LEKNKD + E  + + + S  K L +LF   
Sbjct: 540  KPRL----SNKAFIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLPELFQDD 595

Query: 625  -----------SGAQTAEGEGAGGGAKKGGKKKGSSFQTVSALFRENLNKLMTNLRSTHP 673
                       SG        A     + G+      +TV   FR +L+ LM  L +T P
Sbjct: 596  EKAISPTSATSSGRTPLTRTPAKPTKGRPGQMAKEHKKTVGHQFRNSLHLLMETLNATTP 655

Query: 674  HFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNA 733
            H+VRCI PN+ K P   + +  + QLR  GVLE IRI   GFPSR  Y +F  RY+VL  
Sbjct: 656  HYVRCIKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRVLMK 715

Query: 734  SAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDDKLAQLITR 793
                +    D K+  + +L  + +D  +Y+FG TK+FF+AG +  LE++R DKL     R
Sbjct: 716  Q---KDVLSDRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKLRADKLRAACIR 772

Query: 794  TQARCRGFLARVEYQRMVERREAIFCIQYNIRSFM---------NVKHWPWMKLFFKIKP 844
             Q   RG+L R +Y RM   R+A   +Q  +R +            K    ++ ++++  
Sbjct: 773  IQKTIRGWLLRKKYLRM---RKAAITMQRYVRGYQARCYAKFLRRTKAATIIQKYWRMYV 829

Query: 845  LLKSAETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKE----------KNDL- 893
            + +  +  +    + + +  ++  LA++  ++   E K V + K           K  + 
Sbjct: 830  VRRRYKIRRAATIVLQSY--LRGFLARNRYRKILREHKAVIIQKRVRGWLARTHYKRSMH 887

Query: 894  ----------QLQVQAEAEGLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELT 943
                      ++  + E + L       ++  K  I +E KI ++  + +++ +    L 
Sbjct: 888  AIIYLQCCFRRMMAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLV 947

Query: 944  AKKRKLE----DECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLT 999
             K   LE     E  +L+ D++ L+L+    E+E      +V +L EE+A L + + +  
Sbjct: 948  EKLTNLEGIYNSETEKLRSDLERLQLS----EEEAKVATGRVLSLQEEIAKLRKDLEQTR 1003

Query: 1000 KEKKALQE---AHQQTLDDLQAEEDKVNTLTKAK-----IKLEQQVDDLEGSLEQE---- 1047
             EKK ++E    ++Q  + L +   + NTL K +      ++ QQ  ++  ++E++    
Sbjct: 1004 SEKKCIEEHADRYKQETEQLVSNLKEENTLLKQEKEALNHRIVQQAKEMTETMEKKLVEE 1063

Query: 1048 -KKLRMDL--ERAK-RKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDE 1103
             K+L +DL  ER + + L  +    +E   D++ E   +    K       +  S  E E
Sbjct: 1064 TKQLELDLNDERLRYQNLLNEFSRLEERYDDLKEEMTLMVHVPKPGHKRTDSTHSSNESE 1123

Query: 1104 QALGIQLQKKIKELQARIEE-LEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGA 1162
                 ++  +++++ +R EE  E+++  + +   K +K+ ++L +E + + + L+     
Sbjct: 1124 YIFSSEI-AEMEDIPSRTEEPSEKKVPLDMSLFLKLQKRVTELEQEKQVMQDELDR---- 1178

Query: 1163 TSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQK 1222
               Q+  +K +E E    R  +  A L++E+                          +Q+
Sbjct: 1179 KEEQVLRSKAKEEE----RPQIRGAELEYESLK------------------------RQE 1210

Query: 1223 LEKEKSEMKMEIDDL--ASNVETVSKAKGNLEKMCRTLEDQLS----ELKSKEEEQQRLI 1276
            LE E  ++K E+++L  A + ++  +         R L +QL+    EL  ++EE   L 
Sbjct: 1211 LESENKKLKNELNELRKALSEKSAPEVTAPGAPAYRVLMEQLTSVSEELDVRKEEVLILR 1270

Query: 1277 NDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALA 1336
            + L +Q+  +Q +        D+K  +            + ++++K +  E  +A   L 
Sbjct: 1271 SQLVSQKEAIQPK--------DDKNTMTD-----STILLEDVQKMKDK-GEIAQAYIGLK 1316

Query: 1337 HALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAK 1396
               +SS  D   L E  E     +  L++A     +++   +  +E +A     E++  K
Sbjct: 1317 ETNRSSALDYHELNEDGELWLVYEG-LKQANRLLESQLQSQKRSHENEAEALRGEIQSLK 1375

Query: 1397 KK-------LAQRLQ-AAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAAL 1448
            ++       LAQ LQ   E  +E      ASL+    RL NE  DLM  +E+ +     L
Sbjct: 1376 EENNRQQQLLAQNLQLPPEARIE------ASLQHEITRLTNENLDLMEQLEKQDKTVRKL 1429

Query: 1449 DKKQRNFDKILAE 1461
             K+ + F K + E
Sbjct: 1430 KKQLKVFAKKIGE 1442



 Score =  100 bits (248), Expect = 2e-20
 Identities = 180/793 (22%), Positives = 324/793 (40%), Gaps = 106/793 (13%)

Query: 795  QARCRGFLARVEYQRMVERREAIFCIQYNIRSFMNVKHWP-WMKLFFKIKPLLKSAETEK 853
            Q+  RGFLAR  Y++++   +A+  IQ  +R ++   H+   M     ++   +    ++
Sbjct: 845  QSYLRGFLARNRYRKILREHKAVI-IQKRVRGWLARTHYKRSMHAIIYLQCCFRRMMAKR 903

Query: 854  EMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCDQ 913
            E+  +K E        A+S  + K+L   M     E   +QLQ + + +   + + +C  
Sbjct: 904  ELKKLKIE--------ARSVERYKKLHIGM-----ENKIMQLQRKVDEQ---NKDYKC-- 945

Query: 914  LIKTKIQLEA-------KIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELT 966
            L++    LE        K++   ER +  EE     T +   L++E ++L+KD++     
Sbjct: 946  LVEKLTNLEGIYNSETEKLRSDLERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSE 1005

Query: 967  LAKVEKE----KHATENKVKNLTEEMAGLDETIAKL-------------TKEKKALQEAH 1009
               +E+     K  TE  V NL EE   L +    L             T EKK ++E  
Sbjct: 1006 KKCIEEHADRYKQETEQLVSNLKEENTLLKQEKEALNHRIVQQAKEMTETMEKKLVEETK 1065

Query: 1010 QQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQ 1069
            Q  L DL  E  +   L     +LE++ DD    L++E  L + + +   K       + 
Sbjct: 1066 QLEL-DLNDERLRYQNLLNEFSRLEERYDD----LKEEMTLMVHVPKPGHKRTDSTHSSN 1120

Query: 1070 ESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIE 1129
            ES     +E  ++++   + E      + K+  + +L ++LQK++ EL+   + +++E++
Sbjct: 1121 ESEYIFSSEIAEMEDIPSRTE---EPSEKKVPLDMSLFLKLQKRVTELEQEKQVMQDELD 1177

Query: 1130 AER----ASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLE 1185
             +      S+AK E++      ELE  S + +E           NKK + E  ++R+ L 
Sbjct: 1178 RKEEQVLRSKAKEEERPQIRGAELEYESLKRQELESE-------NKKLKNELNELRKALS 1230

Query: 1186 EATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVS 1245
                  E +A  +    A +   L EQ   L  V ++L+  K E+ +    L S  E + 
Sbjct: 1231 ------EKSAPEVTAPGAPAYRVLMEQ---LTSVSEELDVRKEEVLILRSQLVSQKEAIQ 1281

Query: 1246 -KAKGNLEKMCRTLEDQLSELKSKEEEQQRLI-----NDLTAQRGRLQTESGE----FSR 1295
             K   N       L + + ++K K E  Q  I     N  +A       E GE    +  
Sbjct: 1282 PKDDKNTMTDSTILLEDVQKMKDKGEIAQAYIGLKETNRSSALDYHELNEDGELWLVYEG 1341

Query: 1296 QLDEKEALVSQLSRGKQAFTQQIEELKRQL----EEEIKAKNALAHALQ---SSRHDCDL 1348
                   L SQL   K++   + E L+ ++    EE  + +  LA  LQ    +R +  L
Sbjct: 1342 LKQANRLLESQLQSQKRSHENEAEALRGEIQSLKEENNRQQQLLAQNLQLPPEARIEASL 1401

Query: 1349 LREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEE 1408
              E      E+  +L   L K +  V + + + +  A ++  ELE  + +     Q  +E
Sbjct: 1402 QHEITRLTNEN-LDLMEQLEKQDKTVRKLKKQLKVFA-KKIGELEVGQMENISPGQIIDE 1459

Query: 1409 HVEAVNAK------CASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEW 1462
             +  VN           LE  K+  Q  V++L+L+++    A         N    L  +
Sbjct: 1460 PIRPVNIPRKEKDFQGMLEYKKEDEQKLVKNLILELKPRGVAV--------NLIPGLPAY 1511

Query: 1463 KQKCEETHAELEASQKEARSLGTE-LFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQ 1521
                   HA+     ++ RSL T  +  IK   ++  D  ET+     N  + +  L + 
Sbjct: 1512 ILFMCVRHADYLNDDQKVRSLLTSTINSIKKVLKKRGDDFETVSFWLSNTCRFLHCLKQY 1571

Query: 1522 IAEGGKRIHELEK 1534
              E G   H   +
Sbjct: 1572 SGEEGFMKHNTSR 1584



 Score = 79.3 bits (194), Expect = 3e-14
 Identities = 128/572 (22%), Positives = 246/572 (43%), Gaps = 106/572 (18%)

Query: 1086 LKKKEFEISNLQSK-IEDEQALGIQLQKKIKELQARIEE--------LEEEIEAERASRA 1136
            + K+E +   ++++ +E  + L I ++ KI +LQ +++E        +E+    E    +
Sbjct: 900  MAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNS 959

Query: 1137 KAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAA 1196
            + EK RSDL R   ++SE  EEA  AT   + + +    E  K+R+DLE+   + +    
Sbjct: 960  ETEKLRSDLERL--QLSE--EEAKVATGRVLSLQE----EIAKLRKDLEQTRSEKKCI-- 1009

Query: 1197 TLRKKHADSVAELGEQ-IDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMC 1255
               ++HAD   +  EQ + NL+     L++EK          A N   V +AK    +M 
Sbjct: 1010 ---EEHADRYKQETEQLVSNLKEENTLLKQEKE---------ALNHRIVQQAK----EMT 1053

Query: 1256 RTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFT 1315
             T+E +L E      E ++L  DL  +R R Q    EFSR  +  + L  +++       
Sbjct: 1054 ETMEKKLVE------ETKQLELDLNDERLRYQNLLNEFSRLEERYDDLKEEMT-----LM 1102

Query: 1316 QQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRAL----SKAN 1371
              + +   +  +   + N   +   S   + + +  + EE  E K  L  +L     K  
Sbjct: 1103 VHVPKPGHKRTDSTHSSNESEYIFSSEIAEMEDIPSRTEEPSEKKVPLDMSLFLKLQKRV 1162

Query: 1372 TEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEV 1431
            TE+ Q +   + +  ++ E++  +K K  +R Q     +E  + K   LE   ++L+NE+
Sbjct: 1163 TELEQEKQVMQDELDRKEEQVLRSKAKEEERPQIRGAELEYESLKRQELESENKKLKNEL 1222

Query: 1432 EDLMLDVERTNA---------ACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEA-- 1480
             +L   +   +A         A   L ++  +  + L   K++     ++L  SQKEA  
Sbjct: 1223 NELRKALSEKSAPEVTAPGAPAYRVLMEQLTSVSEELDVRKEEVLILRSQL-VSQKEAIQ 1281

Query: 1481 ----RSLGTELFKIKNAYEESLDQLET------LKRENKNLQQEISDLTEQ-----IAEG 1525
                ++  T+   +    ++  D+ E       LK  N++   +  +L E      + EG
Sbjct: 1282 PKDDKNTMTDSTILLEDVQKMKDKGEIAQAYIGLKETNRSSALDYHELNEDGELWLVYEG 1341

Query: 1526 GKRIH-----ELEKIKKQVEQE----KCELQAALEE-------------------AEASL 1557
             K+ +     +L+  K+  E E    + E+Q+  EE                    EASL
Sbjct: 1342 LKQANRLLESQLQSQKRSHENEAEALRGEIQSLKEENNRQQQLLAQNLQLPPEARIEASL 1401

Query: 1558 EHEEGKILRIQLELNQVKSEVDRKIAEKDEEI 1589
            +HE  ++    L+L +   + D+ + +  +++
Sbjct: 1402 QHEITRLTNENLDLMEQLEKQDKTVRKLKKQL 1433



 Score = 56.6 bits (135), Expect = 2e-07
 Identities = 103/477 (21%), Positives = 204/477 (42%), Gaps = 92/477 (19%)

Query: 1472 ELEASQKEARSLGTELFKIKNAYEESLDQLET-LKRENKNLQQEISDLTEQIAEGGKRIH 1530
            EL+  + EARS+     K+    E  + QL+  +  +NK+ +  +  LT      G    
Sbjct: 904  ELKKLKIEARSV-ERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNL---EGIYNS 959

Query: 1531 ELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEK---DE 1587
            E EK++  +E+    LQ + EEA+ +     G++L +Q E+ +++ ++++  +EK   +E
Sbjct: 960  ETEKLRSDLER----LQLSEEEAKVAT----GRVLSLQEEIAKLRKDLEQTRSEKKCIEE 1011

Query: 1588 EIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALR 1647
              D+ K+   ++V ++          + +   LK++ E         LNH     A+ + 
Sbjct: 1012 HADRYKQETEQLVSNL----------KEENTLLKQEKEA--------LNHRIVQQAKEMT 1053

Query: 1648 NYRNTQGILKDTQIHLD---DALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERS 1704
                 + + +  Q+ LD   + LR Q  L E   + ER  +L     EE+   +   +  
Sbjct: 1054 ETMEKKLVEETKQLELDLNDERLRYQNLLNEFSRLEERYDDLK----EEMTLMVHVPKPG 1109

Query: 1705 RKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKA 1764
             K           R    H+ N S        E   S    EMEDI   +R  E   KK 
Sbjct: 1110 HK-----------RTDSTHSSNES--------EYIFSSEIAEMEDI--PSRTEEPSEKKV 1148

Query: 1765 ITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEAR 1824
              D ++  +           L++    +EQ  + +Q  LD  E+  L+   K+ ++ + R
Sbjct: 1149 PLDMSLFLK-----------LQKRVTELEQEKQVMQDELDRKEEQVLRSKAKEEERPQIR 1197

Query: 1825 VRELE------GEVESEQKRNAEAVKGLRK--HERRVKELTYQTEEDRKNIL-RLQDLVD 1875
              ELE       E+ESE K+    +  LRK   E+   E+T       + ++ +L  + +
Sbjct: 1198 GAELEYESLKRQELESENKKLKNELNELRKALSEKSAPEVTAPGAPAYRVLMEQLTSVSE 1257

Query: 1876 KLQAKVKSY---------KRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAESQV 1923
            +L  + +           +++A + ++  NT +     L  ++++ +++ +IA++ +
Sbjct: 1258 ELDVRKEEVLILRSQLVSQKEAIQPKDDKNT-MTDSTILLEDVQKMKDKGEIAQAYI 1313



 Score = 54.3 bits (129), Expect = 1e-06
 Identities = 76/339 (22%), Positives = 136/339 (40%), Gaps = 38/339 (11%)

Query: 1607 LDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDA 1666
            L  E RS     +L   ME  + +++ +++  N+     +    N +GI       L   
Sbjct: 908  LKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNSETEKLRSD 967

Query: 1667 LRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQEL----LDASERVQLL 1722
            L   +  +E+  +   R   LQ EI +LR  LEQT   +K  E+       +  + V  L
Sbjct: 968  LERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKCIEEHADRYKQETEQLVSNL 1027

Query: 1723 HTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTS 1782
              +NT L   K+ L   I Q   EM + ++         KK + +   +  +L  E+   
Sbjct: 1028 KEENTLLKQEKEALNHRIVQQAKEMTETME---------KKLVEETKQLELDLNDERLRY 1078

Query: 1783 AHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQK---------LEARVRELEG--- 1830
             +L      +E+   DL+  +     +   G K+               + + E+E    
Sbjct: 1079 QNLLNEFSRLEERYDDLKEEMTLMVHVPKPGHKRTDSTHSSNESEYIFSSEIAEMEDIPS 1138

Query: 1831 --EVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQA 1888
              E  SE+K   +    L K ++RV EL     E  K ++  QD +D+ + +V   K + 
Sbjct: 1139 RTEEPSEKKVPLDMSLFL-KLQKRVTEL-----EQEKQVM--QDELDRKEEQVLRSKAKE 1190

Query: 1889 EEAEEQSNTNLAKFRKLQHELEEAEERADIAESQVNKLR 1927
            EE  +     L      + ELE   ++    ++++N+LR
Sbjct: 1191 EERPQIRGAELEYESLKRQELESENKKL---KNELNELR 1226


>gi|122937345 myosin VB [Homo sapiens]
          Length = 1848

 Score =  564 bits (1454), Expect = e-160
 Identities = 462/1608 (28%), Positives = 769/1608 (47%), Gaps = 191/1608 (11%)

Query: 36   TSVFVAEPKESFVKGTIQS--REGGK-VTVKTEGGATLT----VKDDQV-FPMNPPKYDK 87
            T V++ +P E +    +    +EG K + ++ E    L     V+ +Q+ F  NP     
Sbjct: 11   TRVWIPDPDEVWRSAELTKDYKEGDKSLQLRLEDETILEYPIDVQRNQLPFLRNPDILVG 70

Query: 88   IEDMAMMTHLHEPAVLYNLKERYA-AWMIYTYSGLFCVTVNPYKWLPVYKPEVVTAYRGK 146
              D+  +++LHEPAVL+NLK R+  +  IYTY G+  V +NPY+ LP+Y  +V+  Y G+
Sbjct: 71   ENDLTALSYLHEPAVLHNLKVRFLESNHIYTYCGIVLVAINPYEQLPIYGQDVIYTYSGQ 130

Query: 147  KRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKK 206
               +  PHIF++++ AY+ M  D +NQSI+++GESGAGKTV+ K  ++YFAT+  +  + 
Sbjct: 131  NMGDMDPHIFAVAEEAYKQMARDEKNQSIIVSGESGAGKTVSAKYAMRYFATVGGSASET 190

Query: 207  KEEITSGKIQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADI 266
                        +E+++++++P++EA GNAKT RNDNSSRFGK+I+I F     +  A++
Sbjct: 191  N-----------IEEKVLASSPIMEAIGNAKTTRNDNSSRFGKYIQIGFDKRYHIIGANM 239

Query: 267  ETYLLEKSRVVFQLKAERSYHIFYQITSNKK-PELIEMLLITTNPYDYPFVSQG-EISVA 324
             TYLLEKSRVVFQ   ER+YHIFYQ+ +    PE  E+ L  T+  D+ + SQG + S+ 
Sbjct: 240  RTYLLEKSRVVFQADDERNYHIFYQLCAAAGLPEFKELAL--TSAEDFFYTSQGGDTSIE 297

Query: 325  SIDDQEELMATDSAIDILGFTNEEKVSIYKLTGAVMHYGNLKFKQKQREEQAEPDGTE-- 382
             +DD E+   T  A  +LG     ++SI+K+  +++H G++         QAE DG    
Sbjct: 298  GVDDAEDFEKTRQAFTLLGVKESHQMSIFKIIASILHLGSVAI-------QAERDGDSCS 350

Query: 383  VADKAAYLQS------LNSADLLKALCYPRVKVGNEYVTKGQTVEQVSNAVGALAKAVYE 436
            ++ +  YL +      +  + +   LC+ ++   +E   K  +++QV NA  ALAK +Y 
Sbjct: 351  ISPQDVYLSNFCRLLGVEHSQMEHWLCHRKLVTTSETYVKTMSLQQVINARNALAKHIYA 410

Query: 437  KMFLWMVARINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHM 496
            ++F W+V  IN+ L T   +  FIGVLDI GFE F+ NS EQ CIN+ NEKLQQ FN H+
Sbjct: 411  QLFGWIVEHINKALHTSLKQHSFIGVLDIYGFETFEVNSFEQFCINYANEKLQQQFNSHV 470

Query: 497  FVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLY 556
            F LEQEEY KE I WT IDF  D   CI+LIE  +GI  +L+EEC  PK TD ++  KLY
Sbjct: 471  FKLEQEEYMKEQIPWTLIDF-YDNQPCIDLIEAKLGILDLLDEECKVPKGTDQNWAQKLY 529

Query: 557  DQHLGKSANFQKPKVVKGKAEAHFALIHYAGVVDYNITGWLEKNKDPLNETVVGLYQKSA 616
            D+H   S +FQKP++    +   F ++H+A  V+Y   G+LEKN+D + E  + + + S 
Sbjct: 530  DRH-SSSQHFQKPRM----SNTAFIIVHFADKVEYLSDGFLEKNRDTVYEEQINILKASK 584

Query: 617  MKTLAQLFSGAQ-----TAEGEGAGG-----GAKKGGKKKGSSFQ-TVSALFRENLNKLM 665
               +A LF   +     T  G+G+        A+   K      + TV   FR +L+ LM
Sbjct: 585  FPLVADLFHDDKDPVPATTPGKGSSSKISVRSARPPMKVSNKEHKKTVGHQFRTSLHLLM 644

Query: 666  TNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFK 725
              L +T PH+VRCI PN+ K P   + +  + QLR  GVLE IRI   G+PSR  Y DF 
Sbjct: 645  ETLNATTPHYVRCIKPNDEKLPFHFDPKRAVQQLRACGVLETIRISAAGYPSRWAYHDFF 704

Query: 726  QRYKVLNASAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDD 785
             RY+VL      E    D K     +L ++  D  +++FG TK+FF+AG +  LE++R D
Sbjct: 705  NRYRVLVKKR--ELANTDKKAICRSVLENLIKDPDKFQFGRTKIFFRAGQVAYLEKLRAD 762

Query: 786  KLAQ---LITRT--------------------QARCRGFLARVEYQRMVERREAI----- 817
            K      +I +T                    Q  CRG LAR   + +   R A+     
Sbjct: 763  KFRTATIMIQKTVRGWLQKVKYHRLKGATLTLQRYCRGHLARRLAEHLRRIRAAVVLQKH 822

Query: 818  FCIQYNIRSFMNVKHWPWMKLFFKIKPLLKSAETEKEMATMKEEFQKIKDELAKSEAKRK 877
            + +Q   +++  V+    +   F     ++    +     M+ +   I+  +    A+R 
Sbjct: 823  YRMQRARQAYQRVRRAAVVIQAFTRAMFVRRTYRQ---VLMEHKATTIQKHVRGWMARRH 879

Query: 878  ELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEE 937
                +   ++ +     L+ + E + L       + L +  + +E K+ ++  + +++  
Sbjct: 880  FQRLRDAAIVIQCAFRMLKARRELKALRIEARSAEHLKRLNVGMENKVVQLQRKIDEQ-- 937

Query: 938  INAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAK 997
             N E      +L    S    +++ L+  L  V  ++   E+    L EE+  L   + +
Sbjct: 938  -NKEFKTLSEQLSVTTSTYTMEVERLKKEL--VHYQQSPGEDTSLRLQEEVESLRTELQR 994

Query: 998  LTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERA 1057
               E+K L++AH +  D+L+                 ++V D    LEQE  L   L+  
Sbjct: 995  AHSERKILEDAHSREKDELR-----------------KRVAD----LEQENAL---LKDE 1030

Query: 1058 KRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKEL 1117
            K +L   +    +     E  +  + E L KKE         +E+E++    L K+  +L
Sbjct: 1031 KEQLNNQILCQSKD----EFAQNSVKENLMKKE---------LEEERSRYQNLVKEYSQL 1077

Query: 1118 QARIEELEEE--IEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREA 1175
            + R + L +E  I  +     +    +S L  +    S    E G    A          
Sbjct: 1078 EQRYDNLRDEMTIIKQTPGHRRNPSNQSSLESDSNYPSISTSEIGDTEDA---------- 1127

Query: 1176 EFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEID 1235
                  + +EE  L+  A   T+  K    V EL ++   LQ   +K E++ S+ K++ +
Sbjct: 1128 -----LQQVEEIGLEKAAMDMTVFLKLQKRVRELEQERKKLQVQLEKREQQDSK-KVQAE 1181

Query: 1236 DLASNVETVSKAKGNLEKMCR-TLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFS 1294
               ++++    A      + R  LE +  +LK+   E ++ + D   Q          +S
Sbjct: 1182 PPQTDIDLDPNADLAYNSLKRQELESENKKLKNDLNELRKAVADQATQNNSSHGSPDSYS 1241

Query: 1295 RQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYE 1354
              L++ +    +L   K    +++  L+ Q+    + + A  +A  +          +  
Sbjct: 1242 LLLNQLKLAHEELEVRK----EEVLILRTQIVSADQRRLAGRNAEPNINARSSWPNSEKH 1297

Query: 1355 EEQESKAELQRALSKANTEVAQWRTKYETDAIQRT-EELEEAKKKLAQRLQAAE-EHVEA 1412
             +QE   E    + + N++   W    E   +    + L++  + L  +LQA   EH E 
Sbjct: 1298 VDQEDAIEAYHGVCQTNSKTEDWGYLNEDGELGLAYQGLKQVARLLEAQLQAQSLEHEEE 1357

Query: 1413 VNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAE 1472
            V    A LE  K+                      +DK+Q+ F + L        E   E
Sbjct: 1358 VEHLKAQLEALKEE---------------------MDKQQQTFCQTLL----LSPEAQVE 1392

Query: 1473 LEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDL--TEQIAEGGKRIH 1530
                Q+ +R L  E   +K   E+       LK++ K   ++  DL   + +A+  ++ H
Sbjct: 1393 FGVQQEISR-LTNENLDLKELVEKLEKNERKLKKQLKIYMKKAQDLEAAQALAQSERKRH 1451

Query: 1531 ELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEV 1578
            EL + +  V++++ + Q  LE       H+E + L I+  +  +K ++
Sbjct: 1452 ELNR-QVTVQRKEKDFQGMLE------YHKEDEALLIRNLVTDLKPQM 1492



 Score = 63.9 bits (154), Expect = 1e-09
 Identities = 129/605 (21%), Positives = 242/605 (40%), Gaps = 107/605 (17%)

Query: 1329 IKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQR 1388
            +KA+  L  AL+      + L+      +    +LQR + + N E      +        
Sbjct: 897  LKARRELK-ALRIEARSAEHLKRLNVGMENKVVQLQRKIDEQNKEFKTLSEQLSVTTSTY 955

Query: 1389 TEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAAL 1448
            T E+E  KK+L    Q+  E              T  RLQ EVE L  +++R ++    L
Sbjct: 956  TMEVERLKKELVHYQQSPGED-------------TSLRLQEEVESLRTELQRAHSERKIL 1002

Query: 1449 --------------------------DKKQRNFDKILAEWKQKCEETHA-------ELEA 1475
                                      D+K++  ++IL + K +  +          ELE 
Sbjct: 1003 EDAHSREKDELRKRVADLEQENALLKDEKEQLNNQILCQSKDEFAQNSVKENLMKKELEE 1062

Query: 1476 SQKEARSLGTELFKIKNAYEESLDQLETLK-----RENKNLQQEISDLTEQIAEGGKRIH 1530
             +   ++L  E  +++  Y+   D++  +K     R N + Q  +   +   +     I 
Sbjct: 1063 ERSRYQNLVKEYSQLEQRYDNLRDEMTIIKQTPGHRRNPSNQSSLESDSNYPSISTSEIG 1122

Query: 1531 ELEKIKKQVEQEKCELQA-------ALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIA 1583
            + E   +QVE+   E  A        L++    LE E  K   +Q++L + + +  +K+ 
Sbjct: 1123 DTEDALQQVEEIGLEKAAMDMTVFLKLQKRVRELEQERKK---LQVQLEKREQQDSKKVQ 1179

Query: 1584 EKDEEID-QLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMA 1642
             +  + D  L  N      S++     E+ S N      KK++ DLNE+         +A
Sbjct: 1180 AEPPQTDIDLDPNADLAYNSLKR---QELESEN------KKLKNDLNELR------KAVA 1224

Query: 1643 AEALRNYRNTQGILKDTQIHLDDALRSQEDL---KEQLAMVERRANLLQAEIEEL---RA 1696
             +A +N  ++ G      + L+    + E+L   KE++ ++  R  ++ A+   L    A
Sbjct: 1225 DQATQN-NSSHGSPDSYSLLLNQLKLAHEELEVRKEEVLIL--RTQIVSADQRRLAGRNA 1281

Query: 1697 TLEQTERSRKIAEQELLDASERVQLLH--------TQNTSLINTKKKL---ETDISQMQG 1745
                  RS     ++ +D  + ++  H        T++   +N   +L      + Q+  
Sbjct: 1282 EPNINARSSWPNSEKHVDQEDAIEAYHGVCQTNSKTEDWGYLNEDGELGLAYQGLKQVAR 1341

Query: 1746 EMEDILQ-EARNAEEKAKKAITDAAMMAEELKKEQDTSAH--LERMKKNMEQTVKDLQLR 1802
             +E  LQ ++   EE+ +        + EE+ K+Q T     L   +  +E  V+    R
Sbjct: 1342 LLEAQLQAQSLEHEEEVEHLKAQLEALKEEMDKQQQTFCQTLLLSPEAQVEFGVQQEISR 1401

Query: 1803 LDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKR--NAEAVKGLRKHERRVKELTYQT 1860
            L   E L L   K+ ++KLE   R+L+ +++   K+  + EA + L + ER+  EL  Q 
Sbjct: 1402 LTN-ENLDL---KELVEKLEKNERKLKKQLKIYMKKAQDLEAAQALAQSERKRHELNRQV 1457

Query: 1861 EEDRK 1865
               RK
Sbjct: 1458 TVQRK 1462



 Score = 47.8 bits (112), Expect = 1e-04
 Identities = 78/371 (21%), Positives = 148/371 (39%), Gaps = 57/371 (15%)

Query: 1607 LDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDA 1666
            L  E RS     RL   ME  + +++ +++  N+           T      T  +  + 
Sbjct: 906  LRIEARSAEHLKRLNVGMENKVVQLQRKIDEQNKEFKTLSEQLSVT------TSTYTMEV 959

Query: 1667 LRSQEDLKE-QLAMVERRANLLQAEIEELRATLEQTERSRKIAE----QELLDASERVQL 1721
             R +++L   Q +  E  +  LQ E+E LR  L++    RKI E    +E  +  +RV  
Sbjct: 960  ERLKKELVHYQQSPGEDTSLRLQEEVESLRTELQRAHSERKILEDAHSREKDELRKRVAD 1019

Query: 1722 LHTQNTSLINTKKKLETDI-----------SQMQGEMEDILQEARNAEEKAKKAITDAAM 1770
            L  +N  L + K++L   I           S  +  M+  L+E R+  +   K  +    
Sbjct: 1020 LEQENALLKDEKEQLNNQILCQSKDEFAQNSVKENLMKKELEEERSRYQNLVKEYSQLEQ 1079

Query: 1771 MAEELKKEQDTSAHLERMKKN----------------MEQTVKDLQLRLDEAEQLALKGG 1814
              + L+ E          ++N                    + D +  L + E++ L+  
Sbjct: 1080 RYDNLRDEMTIIKQTPGHRRNPSNQSSLESDSNYPSISTSEIGDTEDALQQVEEIGLEKA 1139

Query: 1815 KKQIQ---KLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEED-------R 1864
               +    KL+ RVRELE E    +K   +  K  ++  ++V+    QT+ D        
Sbjct: 1140 AMDMTVFLKLQKRVRELEQE---RKKLQVQLEKREQQDSKKVQAEPPQTDIDLDPNADLA 1196

Query: 1865 KNILRLQDLVD---KLQAKVKSYKRQAEEAEEQSNTNLA---KFRKLQHELEEAEERADI 1918
             N L+ Q+L     KL+  +   ++   +   Q+N++      +  L ++L+ A E  ++
Sbjct: 1197 YNSLKRQELESENKKLKNDLNELRKAVADQATQNNSSHGSPDSYSLLLNQLKLAHEELEV 1256

Query: 1919 AESQVNKLRVK 1929
             + +V  LR +
Sbjct: 1257 RKEEVLILRTQ 1267


>gi|28416946 myosin 18A isoform a [Homo sapiens]
          Length = 2054

 Score =  509 bits (1310), Expect = e-143
 Identities = 434/1710 (25%), Positives = 822/1710 (48%), Gaps = 227/1710 (13%)

Query: 58   GKVTVKTE-GGATLTVKDDQVFPMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIY 116
            GKV VK +  GA L V +D V   N P  D++ED+A + +L+E +VL+ L++RY A +++
Sbjct: 376  GKVRVKLDHDGAILDVDEDDVEKANAPSCDRLEDLASLVYLNESSVLHTLRQRYGASLLH 435

Query: 117  TYSGLFCVTVNPYKWLPVYKPEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSIL 176
            TY+G   + + P     VY  +V+  ++G +R++  PHI++++  AY+ ML  R++QSI+
Sbjct: 436  TYAGPSLLVLGPRGAPAVYSEKVMHMFKGCRREDMAPHIYAVAQTAYRAMLMSRQDQSII 495

Query: 177  ITGESGAGKTVNTKRVIQYFATIAVTGEKKKEEITSGKIQGTLEDQIISANPLLEAFGNA 236
            + G SG+GKT + + ++QY ATIA         I+  K+    + Q +    LLEAFGN+
Sbjct: 496  LLGSSGSGKTTSCQHLVQYLATIA--------GISGNKVFSVEKWQALYT--LLEAFGNS 545

Query: 237  KTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVVFQLKAERSYHIFYQITS-- 294
             T+ N N++RF + + + F   G++ASA I+T LLEK RV  +  +E ++++FY + +  
Sbjct: 546  PTIINGNATRFSQILSLDFDQAGQVASASIQTMLLEKLRVARRPASEATFNVFYYLLACG 605

Query: 295  --NKKPELIEMLLITTNPYDYPFVSQGEISVASIDDQEELMATDSAIDILGFTNEEKVSI 352
                + EL    L   N +    +++ E    +     +L A   A+ +LG + +E+ + 
Sbjct: 606  DGTLRTELHLNHLAENNVFGIVPLAKPEEKQKAAQQFSKLQA---AMKVLGISPDEQKAC 662

Query: 353  YKLTGAVMHYGNLKFKQKQREEQAEPDGT-EVADKAAYLQSLNSADLLKALCYPRVKVG- 410
            + +  A+ H G     ++  E   +     E A KAAYL   +  +L  A+   + K G 
Sbjct: 663  WFILAAIYHLGAAGATKEAAEAGRKQFARHEWAQKAAYLLGCSLEELSSAIFKHQHKGGT 722

Query: 411  ---NEYVTKGQTVEQVSNAVG----------ALAKAVYEKMFLWMVARINQQLDTKQPRQ 457
               +    +G     + +  G           +A  +Y ++F  +V+ +N+ L + Q   
Sbjct: 723  LQRSTSFRQGPEESGLGDGTGPKLSALECLEGMAAGLYSELFTLLVSLVNRALKSSQHSL 782

Query: 458  YFIGVLDIAGFEIFDFN------SLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEW 511
              + ++D  GF+  +        S E+LC N+T ++LQ+ F+   FV E E YK+E IE 
Sbjct: 783  CSMMIVDTPGFQNPEQGGSARGASFEELCHNYTQDRLQRLFHERTFVQELERYKEENIEL 842

Query: 512  TFIDF---------GMDLAACIELI------EKPMGIFSILEEECMFPKATDTSFKNKLY 556
             F D           +D A+   L+      ++  G+  +LEEE + P A++ +   +L+
Sbjct: 843  AFDDLEPPTDDSVAAVDQASHQSLVRSLARTDEARGLLWLLEEEALVPGASEDTLLERLF 902

Query: 557  DQHLGKSAN--FQKPKVVKGKAEAHFALIHYAGV--VDYNITGWLEKNK-DPLNETVVGL 611
              +  +  +   Q P +   K   HF L H  G   V+YN+TGWL   K +P  +    L
Sbjct: 903  SYYGPQEGDKKGQSPLLHSSKPH-HFLLGHSHGTNWVEYNVTGWLNYTKQNPATQNAPRL 961

Query: 612  YQKSAMKTLAQLFSG----AQTAEGEGAG--GGAKKGGKKKGSSFQT----VSALFRENL 661
             Q S  K ++ LF G    A    G  AG  GG++   ++  S  +T    ++A+ +++L
Sbjct: 962  LQDSQKKIISNLFLGRAGSATVLSGSIAGLEGGSQLALRRATSMRKTFTTGMAAVKKKSL 1021

Query: 662  --------NKLMTNLRSTHPHFVRCIIP--------------------NETKTPGA---- 689
                    + L+  ++ +  HFV C +P                    +E   P      
Sbjct: 1022 CIQMKLQVDALIDTIKKSKLHFVHCFLPVAEGWAGEPRSASSRRVSSSSELDLPSGDHCE 1081

Query: 690  -----MEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQ---- 740
                 ++  L+  QLR + +L+ +R+ R+G+P  +++++F++R+ VL      +      
Sbjct: 1082 AGLLQLDVPLLRTQLRGSRLLDAMRMYRQGYPDHMVFSEFRRRFDVLAPHLTKKHGRNYI 1141

Query: 741  FIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDDKLAQLITRTQARCRG 800
             +D ++A E+LL  +D++ +    G ++VFF+AG L  LEE RD++ ++ +T  QA CRG
Sbjct: 1142 VVDERRAVEELLECLDLEKSSCCMGLSRVFFRAGTLARLEEQRDEQTSRNLTLFQAACRG 1201

Query: 801  FLARVEYQRMVERREAIFCIQYNIRSFMNVKHWPWMKLFFKIKPLLKSAETEKEMATMKE 860
            +LAR  +++   +  AI C+Q NI+    VK WPW KLF  ++PL++   +E+++    E
Sbjct: 1202 YLARQHFKKRKIQDLAIRCVQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKDE 1261

Query: 861  EFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCDQLIKTKIQ 920
            E Q+++ +L K+E +R EL      L    ++L  ++  E      A +  D     +++
Sbjct: 1262 EIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDAETAERLR 1321

Query: 921  LEAKIKEVTER--AEDEEEINAELTAKKRKLEDECSELKKDIDDLEL---TLAKVEKEKH 975
             E ++KE+  +  A  ++    E+   + +L    +E+  ++DD +       K E+   
Sbjct: 1322 AEKEMKELQTQYDALKKQMEVMEMEVMEARL-IRAAEINGEVDDDDAGGEWRLKYERAVR 1380

Query: 976  ATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDK----VNTLTKAKI 1031
              +   K L +E    ++ +    + K+ L    ++ L DLQA+ ++    +  L K   
Sbjct: 1381 EVDFTKKRLQQE---FEDKLEVEQQNKRQL----ERRLGDLQADSEESQRALQQLKKKCQ 1433

Query: 1032 KLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEF 1091
            +L  ++ D +  LE ++    +LE+ +R+ + +L  A E   + + EK Q ++  ++K+ 
Sbjct: 1434 RLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHE---EAQREKLQREKLQREKDM 1490

Query: 1092 ---EISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRE 1148
               E  +L+ ++E++        +K+  L+A ++++  +   + AS AK +KQ  DL  +
Sbjct: 1491 LLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAK 1550

Query: 1149 LEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAE 1208
            +++  E L+E  G     I+M              LE+A L+ E     +R+ H+  +  
Sbjct: 1551 VKDQEEELDEQAGT----IQM--------------LEQAKLRLEMEMERMRQTHSKEMES 1592

Query: 1209 LGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSK 1268
              E++   +  +Q  +K+  +M++++++   + + V + K  LE    TL DQ++  +  
Sbjct: 1593 RDEEV---EEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVN--RRD 1647

Query: 1269 EEEQQRLINDLTAQRGRL----------------QTESGEFSRQLDEKEALVSQLSRGKQ 1312
             E ++RL  DL   +  L                + E  +   QL+E E   +   + ++
Sbjct: 1648 FESEKRLRKDLKRTKALLADAQLMLDHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARK 1707

Query: 1313 AFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQR----ALS 1368
            A   +IE+L  Q+++  KAK AL   L   + + + ++ + EE+QE   EL +    A++
Sbjct: 1708 AMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVA 1767

Query: 1369 KANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVE-----AVNAKCASLEKT 1423
            +A+ ++AQ       D   + EE  + K++L ++LQA +  VE      V+    S ++ 
Sbjct: 1768 QASRDLAQ-----INDLQAQLEEANKEKQELQEKLQALQSQVEFLEQSMVDKSLVSRQEA 1822

Query: 1424 KQR-LQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARS 1482
            K R L+  +E     V+R  +  + L   + N +K+  E  Q+    + E E +++    
Sbjct: 1823 KIRELETRLEFERTQVKRLESLASRL---KENMEKLTEERDQRIAAENREKEQNKR---- 1875

Query: 1483 LGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQE 1542
                                 L+R+ ++ ++E+ +L  + AE  ++ HELE   + +E  
Sbjct: 1876 ---------------------LQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAA 1914

Query: 1543 KCELQAALEEA-----------EASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQ 1591
               LQA L+ A           E  +E +E + L   L+    K +  +   E D ++D 
Sbjct: 1915 NQSLQADLKLAFKRIGDLQAAIEDEMESDENEDLINSLQDMVTKYQKRKNKLEGDSDVDS 1974

Query: 1592 LKRNHIRIVESMQSTLDAEIRSRNDAIRLK 1621
               + +  V+S  S      ++ +D   LK
Sbjct: 1975 ELEDRVDGVKSWLSKNKGPSKAASDDGSLK 2004



 Score =  186 bits (471), Expect = 3e-46
 Identities = 158/694 (22%), Positives = 330/694 (47%), Gaps = 61/694 (8%)

Query: 1252 EKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQL-DEKEA--LVSQLS 1308
            E+  R  ++++ +L+SK E+ ++  N+L     RL++   E + +L DE+      SQL 
Sbjct: 1253 EEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLL 1312

Query: 1309 RGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQY----EEEQESKAELQ 1364
              + A   + E+  ++L+ +  A       ++    +  L+R        ++ ++  E +
Sbjct: 1313 DAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWR 1372

Query: 1365 RALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTK 1424
                +A  EV   + + + +   + E  ++ K++L +RL   +   E        L+K  
Sbjct: 1373 LKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKC 1432

Query: 1425 QRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLG 1484
            QRL  E++D  L +E        L+KKQR FD  L++  ++ +    + E  Q+E   L 
Sbjct: 1433 QRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLL 1492

Query: 1485 TELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKC 1544
             E F +K   EE    +    ++  +L+ E+ D++ Q     K    L K+KKQ+     
Sbjct: 1493 AEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQ---ESKDEASLAKVKKQLR---- 1545

Query: 1545 ELQAALEEAEASLEHEEGKI-------LRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHI 1597
            +L+A +++ E  L+ + G I       LR+++E+ +++    +++  +DEE+++ +++  
Sbjct: 1546 DLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQ 1605

Query: 1598 RIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALR-NYRNTQGIL 1656
            + ++ M+  L+ E   +   +R K+++EG L  +  Q+N  +  + + LR + + T+ +L
Sbjct: 1606 KKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALL 1665

Query: 1657 KDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDAS 1716
             D Q+ LD  L++    K ++A        L+ ++EE   T     ++RK  E E+ D  
Sbjct: 1666 ADAQLMLDH-LKNSAPSKREIAQ-------LKNQLEESEFTCAAAVKARKAMEVEIED-- 1715

Query: 1717 ERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELK 1776
                 LH Q   +   K  LE  +S++Q E  +I       +E           M E +K
Sbjct: 1716 -----LHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQED----------MNELMK 1760

Query: 1777 KEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQ 1836
            K +   A + +  +++ Q + DLQ +L+EA         K+ Q+L+ +++ L+ +VE  +
Sbjct: 1761 KHK---AAVAQASRDLAQ-INDLQAQLEEA--------NKEKQELQEKLQALQSQVEFLE 1808

Query: 1837 KRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSN 1896
            +   +    + + E +++EL  + E +R  + RL+ L  +L+  ++    + ++     N
Sbjct: 1809 QSMVDK-SLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEERDQRIAAEN 1867

Query: 1897 TNLAKFRKLQHELEEA-EERADIAESQVNKLRVK 1929
                + ++LQ +L +  EE  ++A  +    R K
Sbjct: 1868 REKEQNKRLQRQLRDTKEEMGELARKEAEASRKK 1901



 Score =  154 bits (390), Expect = 6e-37
 Identities = 206/921 (22%), Positives = 402/921 (43%), Gaps = 138/921 (14%)

Query: 945  KKRKLED--ECSELKKDIDDLEL--------TLAKVEKEKHATENKVKNLTEEMAGLDET 994
            ++R +E+  EC +L+K    + L        TLA++E+++   E   +NLT   A     
Sbjct: 1145 ERRAVEELLECLDLEKSSCCMGLSRVFFRAGTLARLEEQRD--EQTSRNLTLFQAACRGY 1202

Query: 995  IAKLTKEKKALQEAH----QQTLDDLQAEED----KVNTLTKAKIKLEQQVDDLEGSLEQ 1046
            +A+   +K+ +Q+      Q+ +   +  +D    K+ T  +  I+++   + +    E+
Sbjct: 1203 LARQHFKKRKIQDLAIRCVQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKDEE 1262

Query: 1047 EKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQAL 1106
             ++LR  LE+A+++   +L+L  + +   E+   +L  +L  +     +    ++ E A 
Sbjct: 1263 IQQLRSKLEKAEKE-RNELRLNSDRL---ESRISELTSELTDERNTGESASQLLDAETAE 1318

Query: 1107 GIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRS-DLSRELEEISERLEEAGGATSA 1165
             ++ +K++KELQ + + L++++E       +A   R+ +++ E+++     ++AGG    
Sbjct: 1319 RLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDD-----DDAGGEWRL 1373

Query: 1166 QIEMNKKREAEFQKMR--RDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKL 1223
            + E    RE +F K R  ++ E+     +     L ++  D  A+  E     QR  Q+L
Sbjct: 1374 KYE-RAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEES----QRALQQL 1428

Query: 1224 EKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQR 1283
            +K+   +  E+ D   ++E        LEK  R  + +LS+   + + ++     L  ++
Sbjct: 1429 KKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREK 1488

Query: 1284 GRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEE----EIKAKNALAHAL 1339
              L  E+    +QL+EK+  ++        FTQ++  L+ +L++    E K + +LA   
Sbjct: 1489 DMLLAEAFSLKQQLEEKDMDIA-------GFTQKVVSLEAELQDISSQESKDEASLAKVK 1541

Query: 1340 QSSRHDCDLLREQYEEEQESKAELQ---RALSKANTEVAQWRTKYETDAIQRTEELEEAK 1396
            +  R     +++Q EE  E    +Q   +A  +   E+ + R  +  +   R EE+EEA+
Sbjct: 1542 KQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEAR 1601

Query: 1397 KKLAQRLQAAEEHVEA--------------VNAKCASLEKTKQRLQNEVED-LMLDVERT 1441
            +   ++L+  E  +E               +  K A+L     R   E E  L  D++RT
Sbjct: 1602 QSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRT 1661

Query: 1442 NAACA----ALD--KKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTEL-------- 1487
             A  A     LD  K      + +A+ K + EE+     A+ K  +++  E+        
Sbjct: 1662 KALLADAQLMLDHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQID 1721

Query: 1488 --FKIKNAYEESLDQLETLKRENKN-LQQEISDLTE-------QIAEGGKRIHELEKIKK 1537
               K K A EE L +L+  K E +N L+++  D+ E        +A+  + + ++  ++ 
Sbjct: 1722 DIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQA 1781

Query: 1538 QVEQ---EKCELQAALEEAEASLE-------------HEEGKILRIQLELNQVKSEVDRK 1581
            Q+E+   EK ELQ  L+  ++ +E              +E KI  ++  L   +++V R 
Sbjct: 1782 QLEEANKEKQELQEKLQALQSQVEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQVKRL 1841

Query: 1582 IAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRM 1641
                +    +LK N  ++ E     + AE R +    RL++++     EM        R 
Sbjct: 1842 ----ESLASRLKENMEKLTEERDQRIAAENREKEQNKRLQRQLRDTKEEM----GELARK 1893

Query: 1642 AAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQT 1701
             AEA R          + ++ L+    + + L+  L +  +R   LQA IE+        
Sbjct: 1894 EAEASRKKH-------ELEMDLESLEAANQSLQADLKLAFKRIGDLQAAIED-------- 1938

Query: 1702 ERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKA 1761
                   E E  +  + +  L    T     K KLE D S +  E+ED +   ++   K 
Sbjct: 1939 -------EMESDENEDLINSLQDMVTKYQKRKNKLEGD-SDVDSELEDRVDGVKSWLSK- 1989

Query: 1762 KKAITDAAMMAEELKKEQDTS 1782
             K  + AA     LK    TS
Sbjct: 1990 NKGPSKAASDDGSLKSSSPTS 2010



 Score = 81.6 bits (200), Expect = 7e-15
 Identities = 68/301 (22%), Positives = 146/301 (48%), Gaps = 11/301 (3%)

Query: 1650 RNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAE 1709
            RN    ++  +  L+ A + + +L+     +E R + L +E+ + R T E   +      
Sbjct: 1257 RNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDAET 1316

Query: 1710 QELLDASERVQLLHTQNTSLINTKKKLETDI--------SQMQGEMEDILQEARNAEEKA 1761
             E L A + ++ L TQ  +L    + +E ++        +++ GE++D          K 
Sbjct: 1317 AERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDD-DAGGEWRLKY 1375

Query: 1762 KKAITDAAMMAEELKKEQDTSAHLERM-KKNMEQTVKDLQLRLDEAEQLALKGGKKQIQK 1820
            ++A+ +     + L++E +    +E+  K+ +E+ + DLQ   +E+++ AL+  KK+ Q+
Sbjct: 1376 ERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQR-ALQQLKKKCQR 1434

Query: 1821 LEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAK 1880
            L A +++ +  +E +Q RN E  K  R+ +  + +   + + ++    +LQ   D L A+
Sbjct: 1435 LTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAE 1494

Query: 1881 VKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAESQVNKLRVKSREVHTKVISE 1940
              S K+Q EE +        K   L+ EL++   +    E+ + K++ + R++  KV  +
Sbjct: 1495 AFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQ 1554

Query: 1941 E 1941
            E
Sbjct: 1555 E 1555



 Score = 56.6 bits (135), Expect = 2e-07
 Identities = 68/267 (25%), Positives = 124/267 (46%), Gaps = 44/267 (16%)

Query: 1676 QLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKK 1735
            ++ + E +      EI++LR+ LE+ E+ R     EL   S+R                 
Sbjct: 1248 EVQLSEEQIRNKDEEIQQLRSKLEKAEKERN----ELRLNSDR----------------- 1286

Query: 1736 LETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKE---QDTSAHLERMKKNM 1792
            LE+ IS++  E+ D     RN  E A + +   A  AE L+ E   ++     + +KK M
Sbjct: 1287 LESRISELTSELTD----ERNTGESASQLLD--AETAERLRAEKEMKELQTQYDALKKQM 1340

Query: 1793 E-QTVKDLQLRLDEAEQLALK------GGKKQIQKLEARVRELEG-----EVESEQKRNA 1840
            E   ++ ++ RL  A ++  +      GG+ ++ K E  VRE++      + E E K   
Sbjct: 1341 EVMEMEVMEARLIRAAEINGEVDDDDAGGEWRL-KYERAVREVDFTKKRLQQEFEDKLEV 1399

Query: 1841 EAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLA 1900
            E  +  R+ ERR+ +L   +EE ++ + +L+    +L A+++  K   E  + +++    
Sbjct: 1400 EQ-QNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEK 1458

Query: 1901 KFRKLQHELEEAEERADIAESQVNKLR 1927
            K R+   EL +A E A   + Q  KL+
Sbjct: 1459 KQRRFDSELSQAHEEAQREKLQREKLQ 1485



 Score = 34.7 bits (78), Expect = 0.93
 Identities = 33/143 (23%), Positives = 69/143 (48%), Gaps = 6/143 (4%)

Query: 1793 EQTVKDLQLRLDEAEQLALKGGKK-QIQKLEARVREL-EGEVESEQKRNA-EAVKGLRKH 1849
            ++ ++DL +R  +      KG K     KL   VR L E ++  EQ RN  E ++ LR  
Sbjct: 1210 KRKIQDLAIRCVQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKDEEIQQLRS- 1268

Query: 1850 ERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHEL 1909
              ++++   +  E R N  RL+  + +L +++   +   E A +  +   A+  + + E+
Sbjct: 1269 --KLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDAETAERLRAEKEM 1326

Query: 1910 EEAEERADIAESQVNKLRVKSRE 1932
            +E + + D  + Q+  + ++  E
Sbjct: 1327 KELQTQYDALKKQMEVMEMEVME 1349


>gi|42794779 myosin 18A isoform b [Homo sapiens]
          Length = 2039

 Score =  506 bits (1304), Expect = e-143
 Identities = 428/1678 (25%), Positives = 814/1678 (48%), Gaps = 226/1678 (13%)

Query: 58   GKVTVKTE-GGATLTVKDDQVFPMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIY 116
            GKV VK +  GA L V +D V   N P  D++ED+A + +L+E +VL+ L++RY A +++
Sbjct: 376  GKVRVKLDHDGAILDVDEDDVEKANAPSCDRLEDLASLVYLNESSVLHTLRQRYGASLLH 435

Query: 117  TYSGLFCVTVNPYKWLPVYKPEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSIL 176
            TY+G   + + P     VY  +V+  ++G +R++  PHI++++  AY+ ML  R++QSI+
Sbjct: 436  TYAGPSLLVLGPRGAPAVYSEKVMHMFKGCRREDMAPHIYAVAQTAYRAMLMSRQDQSII 495

Query: 177  ITGESGAGKTVNTKRVIQYFATIAVTGEKKKEEITSGKIQGTLEDQIISANPLLEAFGNA 236
            + G SG+GKT + + ++QY ATIA         I+  K+    + Q +    LLEAFGN+
Sbjct: 496  LLGSSGSGKTTSCQHLVQYLATIA--------GISGNKVFSVEKWQALYT--LLEAFGNS 545

Query: 237  KTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVVFQLKAERSYHIFYQITS-- 294
             T+ N N++RF + + + F   G++ASA I+T LLEK RV  +  +E ++++FY + +  
Sbjct: 546  PTIINGNATRFSQILSLDFDQAGQVASASIQTMLLEKLRVARRPASEATFNVFYYLLACG 605

Query: 295  --NKKPELIEMLLITTNPYDYPFVSQGEISVASIDDQEELMATDSAIDILGFTNEEKVSI 352
                + EL    L   N +    +++ E    +     +L A   A+ +LG + +E+ + 
Sbjct: 606  DGTLRTELHLNHLAENNVFGIVPLAKPEEKQKAAQQFSKLQA---AMKVLGISPDEQKAC 662

Query: 353  YKLTGAVMHYGNLKFKQKQREEQAEPDGT-EVADKAAYLQSLNSADLLKALCYPRVKVG- 410
            + +  A+ H G     ++  E   +     E A KAAYL   +  +L  A+   + K G 
Sbjct: 663  WFILAAIYHLGAAGATKEAAEAGRKQFARHEWAQKAAYLLGCSLEELSSAIFKHQHKGGT 722

Query: 411  ---NEYVTKGQTVEQVSNAVG----------ALAKAVYEKMFLWMVARINQQLDTKQPRQ 457
               +    +G     + +  G           +A  +Y ++F  +V+ +N+ L + Q   
Sbjct: 723  LQRSTSFRQGPEESGLGDGTGPKLSALECLEGMAAGLYSELFTLLVSLVNRALKSSQHSL 782

Query: 458  YFIGVLDIAGFEIFDFN------SLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEW 511
              + ++D  GF+  +        S E+LC N+T ++LQ+ F+   FV E E YK+E IE 
Sbjct: 783  CSMMIVDTPGFQNPEQGGSARGASFEELCHNYTQDRLQRLFHERTFVQELERYKEENIEL 842

Query: 512  TFIDF---------GMDLAACIELI------EKPMGIFSILEEECMFPKATDTSFKNKLY 556
             F D           +D A+   L+      ++  G+  +LEEE + P A++ +   +L+
Sbjct: 843  AFDDLEPPTDDSVAAVDQASHQSLVRSLARTDEARGLLWLLEEEALVPGASEDTLLERLF 902

Query: 557  DQHLGKSAN--FQKPKVVKGKAEAHFALIHYAGV--VDYNITGWLEKNK-DPLNETVVGL 611
              +  +  +   Q P +   K   HF L H  G   V+YN+TGWL   K +P  +    L
Sbjct: 903  SYYGPQEGDKKGQSPLLHSSKPH-HFLLGHSHGTNWVEYNVTGWLNYTKQNPATQNAPRL 961

Query: 612  YQKSAMKTLAQLFSG----AQTAEGEGAG--GGAKKGGKKKGSSFQT----VSALFRENL 661
             Q S  K ++ LF G    A    G  AG  GG++   ++  S  +T    ++A+ +++L
Sbjct: 962  LQDSQKKIISNLFLGRAGSATVLSGSIAGLEGGSQLALRRATSMRKTFTTGMAAVKKKSL 1021

Query: 662  --------NKLMTNLRSTHPHFVRCIIP--------------------NETKTPGA---- 689
                    + L+  ++ +  HFV C +P                    +E   P      
Sbjct: 1022 CIQMKLQVDALIDTIKKSKLHFVHCFLPVAEGWAGEPRSASSRRVSSSSELDLPSGDHCE 1081

Query: 690  -----MEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQ---- 740
                 ++  L+  QLR + +L+ +R+ R+G+P  +++++F++R+ VL      +      
Sbjct: 1082 AGLLQLDVPLLRTQLRGSRLLDAMRMYRQGYPDHMVFSEFRRRFDVLAPHLTKKHGRNYI 1141

Query: 741  FIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDDKLAQLITRTQARCRG 800
             +D ++A E+LL  +D++ +    G ++VFF+AG L  LEE RD++ ++ +T  QA CRG
Sbjct: 1142 VVDERRAVEELLECLDLEKSSCCMGLSRVFFRAGTLARLEEQRDEQTSRNLTLFQAACRG 1201

Query: 801  FLARVEYQRMVERREAIFCIQYNIRSFMNVKHWPWMKLFFKIKPLLKSAETEKEMATMKE 860
            +LAR  +++   +  AI C+Q NI+    VK WPW KLF  ++PL++   +E+++    E
Sbjct: 1202 YLARQHFKKRKIQDLAIRCVQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKDE 1261

Query: 861  EFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCDQLIKTKIQ 920
            E Q+++ +L K+E +R EL      L    ++L  ++  E      A +  D     +++
Sbjct: 1262 EIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDAETAERLR 1321

Query: 921  LEAKIKEVTER--AEDEEEINAELTAKKRKLEDECSELKKDIDDLEL---TLAKVEKEKH 975
             E ++KE+  +  A  ++    E+   + +L    +E+  ++DD +       K E+   
Sbjct: 1322 AEKEMKELQTQYDALKKQMEVMEMEVMEARL-IRAAEINGEVDDDDAGGEWRLKYERAVR 1380

Query: 976  ATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDK----VNTLTKAKI 1031
              +   K L +E    ++ +    + K+ L    ++ L DLQA+ ++    +  L K   
Sbjct: 1381 EVDFTKKRLQQE---FEDKLEVEQQNKRQL----ERRLGDLQADSEESQRALQQLKKKCQ 1433

Query: 1032 KLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEF 1091
            +L  ++ D +  LE ++    +LE+ +R+ + +L  A E   + + EK Q ++  ++K+ 
Sbjct: 1434 RLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHE---EAQREKLQREKLQREKDM 1490

Query: 1092 ---EISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRE 1148
               E  +L+ ++E++        +K+  L+A ++++  +   + AS AK +KQ  DL  +
Sbjct: 1491 LLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAK 1550

Query: 1149 LEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAE 1208
            +++  E L+E  G     I+M              LE+A L+ E     +R+ H+  +  
Sbjct: 1551 VKDQEEELDEQAGT----IQM--------------LEQAKLRLEMEMERMRQTHSKEMES 1592

Query: 1209 LGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSK 1268
              E++   +  +Q  +K+  +M++++++   + + V + K  LE    TL DQ++  +  
Sbjct: 1593 RDEEV---EEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVN--RRD 1647

Query: 1269 EEEQQRLINDLTAQRGRL----------------QTESGEFSRQLDEKEALVSQLSRGKQ 1312
             E ++RL  DL   +  L                + E  +   QL+E E   +   + ++
Sbjct: 1648 FESEKRLRKDLKRTKALLADAQLMLDHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARK 1707

Query: 1313 AFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQR----ALS 1368
            A   +IE+L  Q+++  KAK AL   L   + + + ++ + EE+QE   EL +    A++
Sbjct: 1708 AMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVA 1767

Query: 1369 KANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVE-----AVNAKCASLEKT 1423
            +A+ ++AQ       D   + EE  + K++L ++LQA +  VE      V+    S ++ 
Sbjct: 1768 QASRDLAQ-----INDLQAQLEEANKEKQELQEKLQALQSQVEFLEQSMVDKSLVSRQEA 1822

Query: 1424 KQR-LQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARS 1482
            K R L+  +E     V+R  +  + L   + N +K+  E  Q+    + E E +++    
Sbjct: 1823 KIRELETRLEFERTQVKRLESLASRL---KENMEKLTEERDQRIAAENREKEQNKR---- 1875

Query: 1483 LGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQE 1542
                                 L+R+ ++ ++E+ +L  + AE  ++ HELE   + +E  
Sbjct: 1876 ---------------------LQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAA 1914

Query: 1543 KCELQAALE-------EAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLK 1593
               LQA L+       + +A++E E        L  ++  S+VD   +E ++ +D +K
Sbjct: 1915 NQSLQADLKLAFKRIGDLQAAIEDEMESDENEDLINSEGDSDVD---SELEDRVDGVK 1969



 Score =  186 bits (471), Expect = 3e-46
 Identities = 158/694 (22%), Positives = 330/694 (47%), Gaps = 61/694 (8%)

Query: 1252 EKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQL-DEKEA--LVSQLS 1308
            E+  R  ++++ +L+SK E+ ++  N+L     RL++   E + +L DE+      SQL 
Sbjct: 1253 EEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLL 1312

Query: 1309 RGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQY----EEEQESKAELQ 1364
              + A   + E+  ++L+ +  A       ++    +  L+R        ++ ++  E +
Sbjct: 1313 DAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWR 1372

Query: 1365 RALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTK 1424
                +A  EV   + + + +   + E  ++ K++L +RL   +   E        L+K  
Sbjct: 1373 LKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKC 1432

Query: 1425 QRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLG 1484
            QRL  E++D  L +E        L+KKQR FD  L++  ++ +    + E  Q+E   L 
Sbjct: 1433 QRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLL 1492

Query: 1485 TELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKC 1544
             E F +K   EE    +    ++  +L+ E+ D++ Q     K    L K+KKQ+     
Sbjct: 1493 AEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQ---ESKDEASLAKVKKQLR---- 1545

Query: 1545 ELQAALEEAEASLEHEEGKI-------LRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHI 1597
            +L+A +++ E  L+ + G I       LR+++E+ +++    +++  +DEE+++ +++  
Sbjct: 1546 DLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQ 1605

Query: 1598 RIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALR-NYRNTQGIL 1656
            + ++ M+  L+ E   +   +R K+++EG L  +  Q+N  +  + + LR + + T+ +L
Sbjct: 1606 KKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALL 1665

Query: 1657 KDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDAS 1716
             D Q+ LD  L++    K ++A        L+ ++EE   T     ++RK  E E+ D  
Sbjct: 1666 ADAQLMLDH-LKNSAPSKREIAQ-------LKNQLEESEFTCAAAVKARKAMEVEIED-- 1715

Query: 1717 ERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELK 1776
                 LH Q   +   K  LE  +S++Q E  +I       +E           M E +K
Sbjct: 1716 -----LHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQED----------MNELMK 1760

Query: 1777 KEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQ 1836
            K +   A + +  +++ Q + DLQ +L+EA         K+ Q+L+ +++ L+ +VE  +
Sbjct: 1761 KHK---AAVAQASRDLAQ-INDLQAQLEEA--------NKEKQELQEKLQALQSQVEFLE 1808

Query: 1837 KRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSN 1896
            +   +    + + E +++EL  + E +R  + RL+ L  +L+  ++    + ++     N
Sbjct: 1809 QSMVDK-SLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEERDQRIAAEN 1867

Query: 1897 TNLAKFRKLQHELEEA-EERADIAESQVNKLRVK 1929
                + ++LQ +L +  EE  ++A  +    R K
Sbjct: 1868 REKEQNKRLQRQLRDTKEEMGELARKEAEASRKK 1901



 Score =  147 bits (372), Expect = 8e-35
 Identities = 185/832 (22%), Positives = 372/832 (44%), Gaps = 121/832 (14%)

Query: 945  KKRKLED--ECSELKKDIDDLEL--------TLAKVEKEKHATENKVKNLTEEMAGLDET 994
            ++R +E+  EC +L+K    + L        TLA++E+++   E   +NLT   A     
Sbjct: 1145 ERRAVEELLECLDLEKSSCCMGLSRVFFRAGTLARLEEQRD--EQTSRNLTLFQAACRGY 1202

Query: 995  IAKLTKEKKALQEAH----QQTLDDLQAEED----KVNTLTKAKIKLEQQVDDLEGSLEQ 1046
            +A+   +K+ +Q+      Q+ +   +  +D    K+ T  +  I+++   + +    E+
Sbjct: 1203 LARQHFKKRKIQDLAIRCVQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKDEE 1262

Query: 1047 EKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQAL 1106
             ++LR  LE+A+++   +L+L  + +   E+   +L  +L  +     +    ++ E A 
Sbjct: 1263 IQQLRSKLEKAEKE-RNELRLNSDRL---ESRISELTSELTDERNTGESASQLLDAETAE 1318

Query: 1107 GIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRS-DLSRELEEISERLEEAGGATSA 1165
             ++ +K++KELQ + + L++++E       +A   R+ +++ E+++     ++AGG    
Sbjct: 1319 RLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDD-----DDAGGEWRL 1373

Query: 1166 QIEMNKKREAEFQKMR--RDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKL 1223
            + E    RE +F K R  ++ E+     +     L ++  D  A+  E     QR  Q+L
Sbjct: 1374 KYE-RAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEES----QRALQQL 1428

Query: 1224 EKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQR 1283
            +K+   +  E+ D   ++E        LEK  R  + +LS+   + + ++     L  ++
Sbjct: 1429 KKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREK 1488

Query: 1284 GRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEE----EIKAKNALAHAL 1339
              L  E+    +QL+EK+  ++        FTQ++  L+ +L++    E K + +LA   
Sbjct: 1489 DMLLAEAFSLKQQLEEKDMDIA-------GFTQKVVSLEAELQDISSQESKDEASLAKVK 1541

Query: 1340 QSSRHDCDLLREQYEEEQESKAELQ---RALSKANTEVAQWRTKYETDAIQRTEELEEAK 1396
            +  R     +++Q EE  E    +Q   +A  +   E+ + R  +  +   R EE+EEA+
Sbjct: 1542 KQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEAR 1601

Query: 1397 KKLAQRLQAAEEHVEA--------------VNAKCASLEKTKQRLQNEVED-LMLDVERT 1441
            +   ++L+  E  +E               +  K A+L     R   E E  L  D++RT
Sbjct: 1602 QSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRT 1661

Query: 1442 NAACA----ALD--KKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTEL-------- 1487
             A  A     LD  K      + +A+ K + EE+     A+ K  +++  E+        
Sbjct: 1662 KALLADAQLMLDHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQID 1721

Query: 1488 --FKIKNAYEESLDQLETLKRENKN-LQQEISDLTE-------QIAEGGKRIHELEKIKK 1537
               K K A EE L +L+  K E +N L+++  D+ E        +A+  + + ++  ++ 
Sbjct: 1722 DIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQA 1781

Query: 1538 QVEQ---EKCELQAALEEAEASLE-------------HEEGKILRIQLELNQVKSEVDRK 1581
            Q+E+   EK ELQ  L+  ++ +E              +E KI  ++  L   +++V R 
Sbjct: 1782 QLEEANKEKQELQEKLQALQSQVEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQVKRL 1841

Query: 1582 IAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRM 1641
                +    +LK N  ++ E     + AE R +    RL++++     EM        R 
Sbjct: 1842 ----ESLASRLKENMEKLTEERDQRIAAENREKEQNKRLQRQLRDTKEEM----GELARK 1893

Query: 1642 AAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEE 1693
             AEA R          + ++ L+    + + L+  L +  +R   LQA IE+
Sbjct: 1894 EAEASRKKH-------ELEMDLESLEAANQSLQADLKLAFKRIGDLQAAIED 1938



 Score = 81.6 bits (200), Expect = 7e-15
 Identities = 68/301 (22%), Positives = 146/301 (48%), Gaps = 11/301 (3%)

Query: 1650 RNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAE 1709
            RN    ++  +  L+ A + + +L+     +E R + L +E+ + R T E   +      
Sbjct: 1257 RNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDAET 1316

Query: 1710 QELLDASERVQLLHTQNTSLINTKKKLETDI--------SQMQGEMEDILQEARNAEEKA 1761
             E L A + ++ L TQ  +L    + +E ++        +++ GE++D          K 
Sbjct: 1317 AERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDD-DAGGEWRLKY 1375

Query: 1762 KKAITDAAMMAEELKKEQDTSAHLERM-KKNMEQTVKDLQLRLDEAEQLALKGGKKQIQK 1820
            ++A+ +     + L++E +    +E+  K+ +E+ + DLQ   +E+++ AL+  KK+ Q+
Sbjct: 1376 ERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQR-ALQQLKKKCQR 1434

Query: 1821 LEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAK 1880
            L A +++ +  +E +Q RN E  K  R+ +  + +   + + ++    +LQ   D L A+
Sbjct: 1435 LTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAE 1494

Query: 1881 VKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAESQVNKLRVKSREVHTKVISE 1940
              S K+Q EE +        K   L+ EL++   +    E+ + K++ + R++  KV  +
Sbjct: 1495 AFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQ 1554

Query: 1941 E 1941
            E
Sbjct: 1555 E 1555



 Score = 56.6 bits (135), Expect = 2e-07
 Identities = 68/267 (25%), Positives = 124/267 (46%), Gaps = 44/267 (16%)

Query: 1676 QLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKK 1735
            ++ + E +      EI++LR+ LE+ E+ R     EL   S+R                 
Sbjct: 1248 EVQLSEEQIRNKDEEIQQLRSKLEKAEKERN----ELRLNSDR----------------- 1286

Query: 1736 LETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKE---QDTSAHLERMKKNM 1792
            LE+ IS++  E+ D     RN  E A + +   A  AE L+ E   ++     + +KK M
Sbjct: 1287 LESRISELTSELTD----ERNTGESASQLLD--AETAERLRAEKEMKELQTQYDALKKQM 1340

Query: 1793 E-QTVKDLQLRLDEAEQLALK------GGKKQIQKLEARVRELEG-----EVESEQKRNA 1840
            E   ++ ++ RL  A ++  +      GG+ ++ K E  VRE++      + E E K   
Sbjct: 1341 EVMEMEVMEARLIRAAEINGEVDDDDAGGEWRL-KYERAVREVDFTKKRLQQEFEDKLEV 1399

Query: 1841 EAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLA 1900
            E  +  R+ ERR+ +L   +EE ++ + +L+    +L A+++  K   E  + +++    
Sbjct: 1400 EQ-QNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEK 1458

Query: 1901 KFRKLQHELEEAEERADIAESQVNKLR 1927
            K R+   EL +A E A   + Q  KL+
Sbjct: 1459 KQRRFDSELSQAHEEAQREKLQREKLQ 1485



 Score = 34.7 bits (78), Expect = 0.93
 Identities = 33/143 (23%), Positives = 69/143 (48%), Gaps = 6/143 (4%)

Query: 1793 EQTVKDLQLRLDEAEQLALKGGKK-QIQKLEARVREL-EGEVESEQKRNA-EAVKGLRKH 1849
            ++ ++DL +R  +      KG K     KL   VR L E ++  EQ RN  E ++ LR  
Sbjct: 1210 KRKIQDLAIRCVQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKDEEIQQLRS- 1268

Query: 1850 ERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHEL 1909
              ++++   +  E R N  RL+  + +L +++   +   E A +  +   A+  + + E+
Sbjct: 1269 --KLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDAETAERLRAEKEM 1326

Query: 1910 EEAEERADIAESQVNKLRVKSRE 1932
            +E + + D  + Q+  + ++  E
Sbjct: 1327 KELQTQYDALKKQMEVMEMEVME 1349


>gi|154354979 myosin X [Homo sapiens]
          Length = 2058

 Score =  491 bits (1265), Expect = e-138
 Identities = 330/1058 (31%), Positives = 562/1058 (53%), Gaps = 59/1058 (5%)

Query: 32   FDAKTSVFVAEPKESFVKGTIQSREGGKVTVKTEGGATLTVKDD-----QVFPMNPPKYD 86
            F   T V++ E  + F   T+ S   G V  +T+ G   T K       +V  M+P   +
Sbjct: 5    FTEGTRVWLRENGQHF-PSTVNSCAEGIVVFRTDYGQVFTYKQSTITHQKVTAMHPTNEE 63

Query: 87   KIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLP-VYKPEVVTAYRG 145
             ++DMA +T LH  +++YNL +RY    IYTY G    +VNPY+ +  +Y+P  +  Y  
Sbjct: 64   GVDDMASLTELHGGSIMYNLFQRYKRNQIYTYIGSILASVNPYQPIAGLYEPATMEQYSR 123

Query: 146  KKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEK 205
            +   E PPHIF+I++  Y+ +    +NQ ILI+GESGAGKT +TK ++++ + I+    +
Sbjct: 124  RHLGELPPHIFAIANECYRCLWKRHDNQCILISGESGAGKTESTKLILKFLSVIS----Q 179

Query: 206  KKEEITSGKIQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASAD 265
            +  E++  +    +E  I+ ++P++EAFGNAKTV N+NSSRFGKF++++    G +    
Sbjct: 180  QSLELSLKEKTSCVERAILESSPIMEAFGNAKTVYNNNSSRFGKFVQLNICQKGNIQGGR 239

Query: 266  IETYLLEKSRVVFQLKAERSYHIFYQITSNKKPELIEMLLITTNPYDYPFVSQ-GEISVA 324
            I  YLLEK+RVV Q   ER+YHIFY + +  + E  E   ++T P +Y +++Q G +   
Sbjct: 240  IVDYLLEKNRVVRQNPGERNYHIFYALLAGLEHEEREEFYLST-PENYHYLNQSGCVEDK 298

Query: 325  SIDDQEELMATDSAIDILGFTNEEKVSIYKLTGAVMHYGNLKFKQKQREEQAEPDGTEVA 384
            +I DQE      +A+D++ F+ EE   + +L   ++H GN++F        A+       
Sbjct: 299  TISDQESFREVITAMDVMQFSKEEVREVSRLLAGILHLGNIEF---ITAGGAQVSFKTAL 355

Query: 385  DKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTVEQVSNAVGALAKAVYEKMFLWMVA 444
             ++A L  L+   L  AL    + +  E +     V+Q  ++  +LA A+Y   F W++ 
Sbjct: 356  GRSAELLGLDPTQLTDALTQRSMFLRGEEILTPLNVQQAVDSRDSLAMALYACCFEWVIK 415

Query: 445  RINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEY 504
            +IN ++   +  +  IG+LDI GFE F+ N  EQ  IN+ NEKLQ++FN H+F LEQ EY
Sbjct: 416  KINSRIKGNEDFK-SIGILDIFGFENFEVNHFEQFNINYANEKLQEYFNKHIFSLEQLEY 474

Query: 505  KKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLYDQHLGKSA 564
             +EG+ W  ID+ +D   C++LIEK +G+ +++ EE  FP+ATD++   KL+ QH   + 
Sbjct: 475  SREGLVWEDIDW-IDNGECLDLIEKKLGLLALINEESHFPQATDSTLLEKLHSQH-ANNH 532

Query: 565  NFQKPKVVKGKAEAHFALIHYAGVVDYNITGWLEKNKDPLNETVVGLYQKSAMKTLAQLF 624
             + KP+V    A  +F + HYAG V Y++ G LEKN+D   + ++ L ++S    +  LF
Sbjct: 533  FYVKPRV----AVNNFGVKHYAGEVQYDVRGILEKNRDTFRDDLLNLLRESRFDFIYDLF 588

Query: 625  SGAQTAEGEGAGGGAKKGGKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPNET 684
                +   +      K G K +     TVS+ F+++L+ LM  L S++P FVRCI PN  
Sbjct: 589  EHVSSRNNQDT---LKCGSKHRR---PTVSSQFKDSLHSLMATLSSSNPFFVRCIKPNMQ 642

Query: 685  KTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNAS-AIPEGQFID 743
            K P   +  +VL+QLR +G+LE +RI + G+  R  + DF +RYKVL  + A+PE    D
Sbjct: 643  KMPDQFDQAVVLNQLRYSGMLETVRIRKAGYAVRRPFQDFYKRYKVLMRNLALPE----D 698

Query: 744  SKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDDKLAQLITRTQARCRGFLA 803
             +     LL   D  +++++ G TKVF +  L   LE+ R+++++      +A   GFLA
Sbjct: 699  VRGKCTSLLQLYDASNSEWQLGKTKVFLRESLEQKLEKRREEEVSHAAMVIRAHVLGFLA 758

Query: 804  RVEYQRMVERREAIFCIQYNIRSFMNVKHWPWMKLFFKIKPLLKSAETEKEMATMKEEFQ 863
            R +Y++++     +  IQ N R+F+        + F  +K      + +      +  ++
Sbjct: 759  RKQYRKVL---YCVVIIQKNYRAFL------LRRRFLHLKKAAIVFQKQLRGQIARRVYR 809

Query: 864  KIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCDQLIKTKIQLEA 923
            ++  E  + E K+K+ EE       EK   + + +       +AE R  Q  +T+ Q E 
Sbjct: 810  QLLAEKREQEEKKKQEEE-------EKKKREEEERERERERREAELRAQQEEETRKQQEL 862

Query: 924  KIKEVTERAEDEEEINAEL-TAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVK 982
               E  ++++ E E+  EL   K+ K  +E   L+K+I+DL+    K ++E   TE  ++
Sbjct: 863  ---EALQKSQKEAELTRELEKQKENKQVEEILRLEKEIEDLQ--RMKEQQELSLTEASLQ 917

Query: 983  NLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEG 1042
             L E     D+ + +L +E     +   ++L+  + +E   N      +  E   +  E 
Sbjct: 918  KLQERR---DQELRRLEEEACRAAQEFLESLNFDEIDECVRNIERSLSVGSEFSSELAES 974

Query: 1043 SLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQ 1080
            + E++          + +++   +   ++  D  N  +
Sbjct: 975  ACEEKPNFNFSQPYPEEEVDEGFEADDDAFKDSPNPSE 1012



 Score = 48.1 bits (113), Expect = 8e-05
 Identities = 63/252 (25%), Positives = 121/252 (48%), Gaps = 32/252 (12%)

Query: 904  LADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDL 963
            L DA     QL KTK+ L   +++  E+  +EE  +A +  +   L       +K    +
Sbjct: 709  LYDASNSEWQLGKTKVFLRESLEQKLEKRREEEVSHAAMVIRAHVLGFLA---RKQYRKV 765

Query: 964  ELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKV 1023
               +  ++K   A   + + L  + A +   + +     +  +  ++Q L + + +E+K 
Sbjct: 766  LYCVVIIQKNYRAFLLRRRFLHLKKAAI---VFQKQLRGQIARRVYRQLLAEKREQEEKK 822

Query: 1024 NTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLD 1083
                    K E++        E++K+   + ER + + E +L+  QE     E  KQQ  
Sbjct: 823  --------KQEEE--------EKKKREEEERERERERREAELRAQQEE----ETRKQQEL 862

Query: 1084 EKLKK--KEFEISN-LQSKIEDEQALGI-QLQKKIKELQARIEELEEEIEAERASRAKAE 1139
            E L+K  KE E++  L+ + E++Q   I +L+K+I++LQ R++E ++E+    AS  K +
Sbjct: 863  EALQKSQKEAELTRELEKQKENKQVEEILRLEKEIEDLQ-RMKE-QQELSLTEASLQKLQ 920

Query: 1140 KQRSDLSRELEE 1151
            ++R    R LEE
Sbjct: 921  ERRDQELRRLEE 932



 Score = 45.8 bits (107), Expect = 4e-04
 Identities = 49/166 (29%), Positives = 82/166 (49%), Gaps = 10/166 (6%)

Query: 1293 FSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQ 1352
            F +QL  +  +  ++ R   A  ++ EE K+Q EEE K +       +  R + + LR Q
Sbjct: 795  FQKQL--RGQIARRVYRQLLAEKREQEEKKKQEEEEKKKREEEERERERERREAE-LRAQ 851

Query: 1353 YEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEA 1412
             EEE   + EL+ AL K+  E    R   +    ++ EE+   +K++ + LQ  +E  E 
Sbjct: 852  QEEETRKQQELE-ALQKSQKEAELTRELEKQKENKQVEEILRLEKEI-EDLQRMKEQQE- 908

Query: 1413 VNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKI 1458
            ++   ASL+K ++R   E+    L+ E   AA   L+    NFD+I
Sbjct: 909  LSLTEASLQKLQERRDQELR--RLEEEACRAAQEFLE--SLNFDEI 950



 Score = 44.3 bits (103), Expect = 0.001
 Identities = 45/193 (23%), Positives = 84/193 (43%), Gaps = 17/193 (8%)

Query: 1047 EKKLRMDL-ERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQA 1105
            +K+LR  +  R  R+L  + +  +E     E EK++ +E+ +++E E    + + + E+ 
Sbjct: 796  QKQLRGQIARRVYRQLLAEKREQEEKKKQEEEEKKKREEEERERERERREAELRAQQEEE 855

Query: 1106 LGIQLQKKIKELQARIEELEEEIEAERASRA-----KAEKQRSDLSRELEEISERLEEAG 1160
               Q + +  +   +  EL  E+E ++ ++      + EK+  DL R  E+    L EA 
Sbjct: 856  TRKQQELEALQKSQKEAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQELSLTEA- 914

Query: 1161 GATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVK 1220
                    + K +E   Q++RR  EEA     A    L   + D + E    I+    V 
Sbjct: 915  -------SLQKLQERRDQELRRLEEEAC---RAAQEFLESLNFDEIDECVRNIERSLSVG 964

Query: 1221 QKLEKEKSEMKME 1233
             +   E +E   E
Sbjct: 965  SEFSSELAESACE 977



 Score = 42.7 bits (99), Expect = 0.003
 Identities = 32/125 (25%), Positives = 62/125 (49%), Gaps = 10/125 (8%)

Query: 1822 EARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKV 1881
            E R +E + + E E+K+  E  +  R+ ERR  EL  Q EE+     R Q  ++ LQ   
Sbjct: 814  EKREQEEKKKQEEEEKKKREEEERERERERREAELRAQQEEE----TRKQQELEALQKSQ 869

Query: 1882 KSYKRQAEEAEEQSNTNLAKFRKLQHELEE-----AEERADIAESQVNKLRVKSREVHTK 1936
            K  +   E  +++ N  + +  +L+ E+E+      ++   + E+ + KL+ + R+   +
Sbjct: 870  KEAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQELSLTEASLQKLQ-ERRDQELR 928

Query: 1937 VISEE 1941
             + EE
Sbjct: 929  RLEEE 933



 Score = 37.7 bits (86), Expect = 0.11
 Identities = 37/179 (20%), Positives = 84/179 (46%), Gaps = 22/179 (12%)

Query: 1718 RVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKK 1777
            R + LH +  +++  +K+L   I++       +L E R  EEK K+         EE KK
Sbjct: 782  RRRFLHLKKAAIV-FQKQLRGQIARRV--YRQLLAEKREQEEKKKQE-------EEEKKK 831

Query: 1778 EQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQK 1837
             ++     ER ++  E       LR  + E+      +++++ L+   +E E   E E++
Sbjct: 832  REEEERERERERREAE-------LRAQQEEETR---KQQELEALQKSQKEAELTRELEKQ 881

Query: 1838 RNAEAVKGLRKHERRVKELTYQTEEDRKNILR--LQDLVDKLQAKVKSYKRQAEEAEEQ 1894
            +  + V+ + + E+ +++L    E+   ++    LQ L ++   +++  + +A  A ++
Sbjct: 882  KENKQVEEILRLEKEIEDLQRMKEQQELSLTEASLQKLQERRDQELRRLEEEACRAAQE 940



 Score = 36.6 bits (83), Expect = 0.25
 Identities = 46/175 (26%), Positives = 80/175 (45%), Gaps = 21/175 (12%)

Query: 1217 QRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLI 1276
            +RV ++L  EK E + +        E   K K   E+  R  E + +EL++++EE+ R  
Sbjct: 805  RRVYRQLLAEKREQEEK-----KKQEEEEKKKREEEERERERERREAELRAQQEEETRKQ 859

Query: 1277 NDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALA 1336
             +L A + + Q E+ E +R+L+            KQ   +Q+EE+ R LE+EI+    + 
Sbjct: 860  QELEALQ-KSQKEA-ELTRELE------------KQKENKQVEEILR-LEKEIEDLQRMK 904

Query: 1337 HALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEE 1391
               + S  +  L + Q   +QE +  L+    +A  E  +     E D   R  E
Sbjct: 905  EQQELSLTEASLQKLQERRDQELR-RLEEEACRAAQEFLESLNFDEIDECVRNIE 958



 Score = 36.6 bits (83), Expect = 0.25
 Identities = 37/147 (25%), Positives = 74/147 (50%), Gaps = 18/147 (12%)

Query: 1449 DKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKREN 1508
            +KK+R  +    E +++ E   AEL A Q+E      EL  ++ + +E+ +    L+++ 
Sbjct: 828  EKKKREEE----ERERERERREAELRAQQEEETRKQQELEALQKSQKEA-ELTRELEKQK 882

Query: 1509 KNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQ 1568
            +N Q       E+I    K I +L+++K+Q  QE    +A+L++ +   E  + ++ R++
Sbjct: 883  ENKQ------VEEILRLEKEIEDLQRMKEQ--QELSLTEASLQKLQ---ERRDQELRRLE 931

Query: 1569 LELNQVKSEVDRKIAEKDEEIDQLKRN 1595
             E  +   E    +    +EID+  RN
Sbjct: 932  EEACRAAQEFLESL--NFDEIDECVRN 956



 Score = 36.2 bits (82), Expect = 0.32
 Identities = 39/156 (25%), Positives = 75/156 (48%), Gaps = 35/156 (22%)

Query: 1261 QLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEE 1320
            Q  E K K EE++R   +   +   L+ +  E +R+  E EAL  Q S+ +   T+++E+
Sbjct: 824  QEEEEKKKREEEERE-RERERREAELRAQQEEETRKQQELEAL--QKSQKEAELTRELEK 880

Query: 1321 LK--RQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWR 1378
             K  +Q+EE ++                  L ++ E+ Q  K + + +L++A+ +  Q R
Sbjct: 881  QKENKQVEEILR------------------LEKEIEDLQRMKEQQELSLTEASLQKLQER 922

Query: 1379 TKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVN 1414
               E   ++R EE         +  +AA+E +E++N
Sbjct: 923  RDQE---LRRLEE---------EACRAAQEFLESLN 946



 Score = 33.1 bits (74), Expect = 2.7
 Identities = 36/117 (30%), Positives = 60/117 (51%), Gaps = 11/117 (9%)

Query: 1518 LTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSE 1577
            L E+  +  K+  E E+ KK+ E+E+ E +    EAE   + EE    R Q EL  ++  
Sbjct: 812  LAEKREQEEKKKQEEEE-KKKREEEERERERERREAELRAQQEEE--TRKQQELEALQK- 867

Query: 1578 VDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQ 1634
              +K AE   E+++ K N  ++ E ++  L+ EI    D  R+K++ E  L E  +Q
Sbjct: 868  -SQKEAELTRELEKQKENK-QVEEILR--LEKEI---EDLQRMKEQQELSLTEASLQ 917


>gi|189083802 myosin VIIA isoform 2 [Homo sapiens]
          Length = 2175

 Score =  481 bits (1238), Expect = e-135
 Identities = 326/926 (35%), Positives = 489/926 (52%), Gaps = 70/926 (7%)

Query: 79  PMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYKPE 138
           PM+P     +EDM  +  L+E  +L NL  RY   +IYTY+G   V VNPY+ L +Y PE
Sbjct: 58  PMHPTSVHGVEDMIRLGDLNEAGILRNLLIRYRDHLIYTYTGSILVAVNPYQLLSIYSPE 117

Query: 139 VVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFAT 198
            +  Y  KK  E PPHIF+I+DN Y  M  +  +Q  +I+GESGAGKT +TK ++Q+ A 
Sbjct: 118 HIRQYTNKKIGEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFLA- 176

Query: 199 IAVTGEKKKEEITSGKIQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTT 258
            A++G+              +E Q++ A P+LEAFGNAKT+RNDNSSRFGK+I IHF   
Sbjct: 177 -AISGQ-----------HSWIEQQVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKR 224

Query: 259 GKLASADIETYLLEKSRVVFQLKAERSYHIFYQITSNKKPELIEMLLITTNPYDYPFVSQ 318
           G +  A IE YLLEKSRV  Q   ER+YH+FY +      +  + L +     DY +++ 
Sbjct: 225 GAIEGAKIEQYLLEKSRVCRQALDERNYHVFYCMLEGMSEDQKKKLGL-GQASDYNYLAM 283

Query: 319 GE-ISVASIDDQEELMATDSAIDILGFTNEEKVSIYKLTGAVMHYGNLKFKQKQRE--EQ 375
           G  I+     D +E     SA+ +L FT+ E   I KL  A++H GNL+++ +  E  + 
Sbjct: 284 GNCITCEGRVDSQEYANIRSAMKVLMFTDTENWEISKLLAAILHLGNLQYEARTFENLDA 343

Query: 376 AEPDGTEVADKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTVEQVSNAVGALAKAVY 435
            E   +     AA L  +N  DL+  L    +    E V+   + EQ  +   A  K +Y
Sbjct: 344 CEVLFSPSLATAASLLEVNPPDLMSCLTSRTLITRGETVSTPLSREQALDVRDAFVKGIY 403

Query: 436 EKMFLWMVARINQQL------DTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQ 489
            ++F+W+V +IN  +      D K  R+  IG+LDI GFE F  NS EQLCINF NE LQ
Sbjct: 404 GRLFVWIVDKINAAIYKPPSQDVKNSRR-SIGLLDIFGFENFAVNSFEQLCINFANEHLQ 462

Query: 490 QFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDT 549
           QFF  H+F LEQEEY  E I+W  I+F  +  A   +  KPM I S+++EE  FPK TDT
Sbjct: 463 QFFVRHVFKLEQEEYDLESIDWLHIEFTDNQDALDMIANKPMNIISLIDEESKFPKGTDT 522

Query: 550 SFKNKLYDQHLGKSANFQKPKVVKGKAEAHFALIHYAGVVDYNITGWLEKNKDPLNETVV 609
           +  +KL  QH   +AN+  P   K   E  F + H+AG+V Y   G+LEKN+D L+  ++
Sbjct: 523 TMLHKLNSQH-KLNANYIPP---KNNHETQFGINHFAGIVYYETQGFLEKNRDTLHGDII 578

Query: 610 GLYQKSAMKTLAQLFSGAQTAEGEGAGGGAKKGGKKKGSSFQTVSALFRENLNKLMTNLR 669
            L   S  K + Q+F  A  A G           +K+     T+S+ F+ +L  LM  L 
Sbjct: 579 QLVHSSRNKFIKQIFQ-ADVAMGAET--------RKRS---PTLSSQFKRSLELLMRTLG 626

Query: 670 STHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYK 729
           +  P FVRCI PNE K P   +  L + QLR +G++E IRI R G+P R  + +F +RY+
Sbjct: 627 ACQPFFVRCIKPNEFKKPMLFDRHLCVRQLRYSGMMETIRIRRAGYPIRYSFVEFVERYR 686

Query: 730 VLNASAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDDKLAQ 789
           VL     P  +  D +   +++  ++   H  ++ G TK+F K     LLE  RD  +  
Sbjct: 687 VLLPGVKPAYKQGDLRGTCQRMAEAVLGTHDDWQIGKTKIFLKDHHDMLLEVERDKAITD 746

Query: 790 LITRTQARCRGFLARVEYQRMVERREAIFCIQYNIRSFMNVKHWPWMKL-FFKIKPLLKS 848
            +   Q   RGF  R  + ++   + A   IQ + R     K++  M+L F +++ L +S
Sbjct: 747 RVILLQKVIRGFKDRSNFLKL---KNAATLIQRHWRGHNCRKNYGLMRLGFLRLQALHRS 803

Query: 849 AETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAE 908
            +  ++    ++   + +    ++   RK    ++  +        L VQA A G+    
Sbjct: 804 RKLHQQYRLARQRIIQFQAR-CRAYLVRKAFRHRLWAV--------LTVQAYARGM--IA 852

Query: 909 ERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKK------RKLEDECSELKKDIDD 962
            R  Q ++ +     + +++  R  +EE++  E++AKK      RK ++  ++L ++  +
Sbjct: 853 RRLHQRLRAEYLWRLEAEKM--RLAEEEKLRKEMSAKKAKEEAERKHQERLAQLAREDAE 910

Query: 963 LELTLAKVEKEKHATENKVKNLTEEM 988
            EL      KEK A   K K L E+M
Sbjct: 911 REL------KEKEAARRK-KELLEQM 929


>gi|189083800 myosin VIIA isoform 3 [Homo sapiens]
          Length = 1204

 Score =  481 bits (1238), Expect = e-135
 Identities = 326/926 (35%), Positives = 489/926 (52%), Gaps = 70/926 (7%)

Query: 79  PMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYKPE 138
           PM+P     +EDM  +  L+E  +L NL  RY   +IYTY+G   V VNPY+ L +Y PE
Sbjct: 58  PMHPTSVHGVEDMIRLGDLNEAGILRNLLIRYRDHLIYTYTGSILVAVNPYQLLSIYSPE 117

Query: 139 VVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFAT 198
            +  Y  KK  E PPHIF+I+DN Y  M  +  +Q  +I+GESGAGKT +TK ++Q+ A 
Sbjct: 118 HIRQYTNKKIGEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFLA- 176

Query: 199 IAVTGEKKKEEITSGKIQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTT 258
            A++G+              +E Q++ A P+LEAFGNAKT+RNDNSSRFGK+I IHF   
Sbjct: 177 -AISGQ-----------HSWIEQQVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKR 224

Query: 259 GKLASADIETYLLEKSRVVFQLKAERSYHIFYQITSNKKPELIEMLLITTNPYDYPFVSQ 318
           G +  A IE YLLEKSRV  Q   ER+YH+FY +      +  + L +     DY +++ 
Sbjct: 225 GAIEGAKIEQYLLEKSRVCRQALDERNYHVFYCMLEGMSEDQKKKLGL-GQASDYNYLAM 283

Query: 319 GE-ISVASIDDQEELMATDSAIDILGFTNEEKVSIYKLTGAVMHYGNLKFKQKQRE--EQ 375
           G  I+     D +E     SA+ +L FT+ E   I KL  A++H GNL+++ +  E  + 
Sbjct: 284 GNCITCEGRVDSQEYANIRSAMKVLMFTDTENWEISKLLAAILHLGNLQYEARTFENLDA 343

Query: 376 AEPDGTEVADKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTVEQVSNAVGALAKAVY 435
            E   +     AA L  +N  DL+  L    +    E V+   + EQ  +   A  K +Y
Sbjct: 344 CEVLFSPSLATAASLLEVNPPDLMSCLTSRTLITRGETVSTPLSREQALDVRDAFVKGIY 403

Query: 436 EKMFLWMVARINQQL------DTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQ 489
            ++F+W+V +IN  +      D K  R+  IG+LDI GFE F  NS EQLCINF NE LQ
Sbjct: 404 GRLFVWIVDKINAAIYKPPSQDVKNSRR-SIGLLDIFGFENFAVNSFEQLCINFANEHLQ 462

Query: 490 QFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDT 549
           QFF  H+F LEQEEY  E I+W  I+F  +  A   +  KPM I S+++EE  FPK TDT
Sbjct: 463 QFFVRHVFKLEQEEYDLESIDWLHIEFTDNQDALDMIANKPMNIISLIDEESKFPKGTDT 522

Query: 550 SFKNKLYDQHLGKSANFQKPKVVKGKAEAHFALIHYAGVVDYNITGWLEKNKDPLNETVV 609
           +  +KL  QH   +AN+  P   K   E  F + H+AG+V Y   G+LEKN+D L+  ++
Sbjct: 523 TMLHKLNSQH-KLNANYIPP---KNNHETQFGINHFAGIVYYETQGFLEKNRDTLHGDII 578

Query: 610 GLYQKSAMKTLAQLFSGAQTAEGEGAGGGAKKGGKKKGSSFQTVSALFRENLNKLMTNLR 669
            L   S  K + Q+F  A  A G           +K+     T+S+ F+ +L  LM  L 
Sbjct: 579 QLVHSSRNKFIKQIFQ-ADVAMGAET--------RKRS---PTLSSQFKRSLELLMRTLG 626

Query: 670 STHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYK 729
           +  P FVRCI PNE K P   +  L + QLR +G++E IRI R G+P R  + +F +RY+
Sbjct: 627 ACQPFFVRCIKPNEFKKPMLFDRHLCVRQLRYSGMMETIRIRRAGYPIRYSFVEFVERYR 686

Query: 730 VLNASAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDDKLAQ 789
           VL     P  +  D +   +++  ++   H  ++ G TK+F K     LLE  RD  +  
Sbjct: 687 VLLPGVKPAYKQGDLRGTCQRMAEAVLGTHDDWQIGKTKIFLKDHHDMLLEVERDKAITD 746

Query: 790 LITRTQARCRGFLARVEYQRMVERREAIFCIQYNIRSFMNVKHWPWMKL-FFKIKPLLKS 848
            +   Q   RGF  R  + ++   + A   IQ + R     K++  M+L F +++ L +S
Sbjct: 747 RVILLQKVIRGFKDRSNFLKL---KNAATLIQRHWRGHNCRKNYGLMRLGFLRLQALHRS 803

Query: 849 AETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAE 908
            +  ++    ++   + +    ++   RK    ++  +        L VQA A G+    
Sbjct: 804 RKLHQQYRLARQRIIQFQAR-CRAYLVRKAFRHRLWAV--------LTVQAYARGM--IA 852

Query: 909 ERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKK------RKLEDECSELKKDIDD 962
            R  Q ++ +     + +++  R  +EE++  E++AKK      RK ++  ++L ++  +
Sbjct: 853 RRLHQRLRAEYLWRLEAEKM--RLAEEEKLRKEMSAKKAKEEAERKHQERLAQLAREDAE 910

Query: 963 LELTLAKVEKEKHATENKVKNLTEEM 988
            EL      KEK A   K K L E+M
Sbjct: 911 REL------KEKEAARRK-KELLEQM 929


>gi|189083798 myosin VIIA isoform 1 [Homo sapiens]
          Length = 2215

 Score =  481 bits (1238), Expect = e-135
 Identities = 326/926 (35%), Positives = 489/926 (52%), Gaps = 70/926 (7%)

Query: 79  PMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYKPE 138
           PM+P     +EDM  +  L+E  +L NL  RY   +IYTY+G   V VNPY+ L +Y PE
Sbjct: 58  PMHPTSVHGVEDMIRLGDLNEAGILRNLLIRYRDHLIYTYTGSILVAVNPYQLLSIYSPE 117

Query: 139 VVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFAT 198
            +  Y  KK  E PPHIF+I+DN Y  M  +  +Q  +I+GESGAGKT +TK ++Q+ A 
Sbjct: 118 HIRQYTNKKIGEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFLA- 176

Query: 199 IAVTGEKKKEEITSGKIQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTT 258
            A++G+              +E Q++ A P+LEAFGNAKT+RNDNSSRFGK+I IHF   
Sbjct: 177 -AISGQ-----------HSWIEQQVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKR 224

Query: 259 GKLASADIETYLLEKSRVVFQLKAERSYHIFYQITSNKKPELIEMLLITTNPYDYPFVSQ 318
           G +  A IE YLLEKSRV  Q   ER+YH+FY +      +  + L +     DY +++ 
Sbjct: 225 GAIEGAKIEQYLLEKSRVCRQALDERNYHVFYCMLEGMSEDQKKKLGL-GQASDYNYLAM 283

Query: 319 GE-ISVASIDDQEELMATDSAIDILGFTNEEKVSIYKLTGAVMHYGNLKFKQKQRE--EQ 375
           G  I+     D +E     SA+ +L FT+ E   I KL  A++H GNL+++ +  E  + 
Sbjct: 284 GNCITCEGRVDSQEYANIRSAMKVLMFTDTENWEISKLLAAILHLGNLQYEARTFENLDA 343

Query: 376 AEPDGTEVADKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTVEQVSNAVGALAKAVY 435
            E   +     AA L  +N  DL+  L    +    E V+   + EQ  +   A  K +Y
Sbjct: 344 CEVLFSPSLATAASLLEVNPPDLMSCLTSRTLITRGETVSTPLSREQALDVRDAFVKGIY 403

Query: 436 EKMFLWMVARINQQL------DTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQ 489
            ++F+W+V +IN  +      D K  R+  IG+LDI GFE F  NS EQLCINF NE LQ
Sbjct: 404 GRLFVWIVDKINAAIYKPPSQDVKNSRR-SIGLLDIFGFENFAVNSFEQLCINFANEHLQ 462

Query: 490 QFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDT 549
           QFF  H+F LEQEEY  E I+W  I+F  +  A   +  KPM I S+++EE  FPK TDT
Sbjct: 463 QFFVRHVFKLEQEEYDLESIDWLHIEFTDNQDALDMIANKPMNIISLIDEESKFPKGTDT 522

Query: 550 SFKNKLYDQHLGKSANFQKPKVVKGKAEAHFALIHYAGVVDYNITGWLEKNKDPLNETVV 609
           +  +KL  QH   +AN+  P   K   E  F + H+AG+V Y   G+LEKN+D L+  ++
Sbjct: 523 TMLHKLNSQH-KLNANYIPP---KNNHETQFGINHFAGIVYYETQGFLEKNRDTLHGDII 578

Query: 610 GLYQKSAMKTLAQLFSGAQTAEGEGAGGGAKKGGKKKGSSFQTVSALFRENLNKLMTNLR 669
            L   S  K + Q+F  A  A G           +K+     T+S+ F+ +L  LM  L 
Sbjct: 579 QLVHSSRNKFIKQIFQ-ADVAMGAET--------RKRS---PTLSSQFKRSLELLMRTLG 626

Query: 670 STHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYK 729
           +  P FVRCI PNE K P   +  L + QLR +G++E IRI R G+P R  + +F +RY+
Sbjct: 627 ACQPFFVRCIKPNEFKKPMLFDRHLCVRQLRYSGMMETIRIRRAGYPIRYSFVEFVERYR 686

Query: 730 VLNASAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDDKLAQ 789
           VL     P  +  D +   +++  ++   H  ++ G TK+F K     LLE  RD  +  
Sbjct: 687 VLLPGVKPAYKQGDLRGTCQRMAEAVLGTHDDWQIGKTKIFLKDHHDMLLEVERDKAITD 746

Query: 790 LITRTQARCRGFLARVEYQRMVERREAIFCIQYNIRSFMNVKHWPWMKL-FFKIKPLLKS 848
            +   Q   RGF  R  + ++   + A   IQ + R     K++  M+L F +++ L +S
Sbjct: 747 RVILLQKVIRGFKDRSNFLKL---KNAATLIQRHWRGHNCRKNYGLMRLGFLRLQALHRS 803

Query: 849 AETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAE 908
            +  ++    ++   + +    ++   RK    ++  +        L VQA A G+    
Sbjct: 804 RKLHQQYRLARQRIIQFQAR-CRAYLVRKAFRHRLWAV--------LTVQAYARGM--IA 852

Query: 909 ERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKK------RKLEDECSELKKDIDD 962
            R  Q ++ +     + +++  R  +EE++  E++AKK      RK ++  ++L ++  +
Sbjct: 853 RRLHQRLRAEYLWRLEAEKM--RLAEEEKLRKEMSAKKAKEEAERKHQERLAQLAREDAE 910

Query: 963 LELTLAKVEKEKHATENKVKNLTEEM 988
            EL      KEK A   K K L E+M
Sbjct: 911 REL------KEKEAARRK-KELLEQM 929


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.128    0.340 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 63,331,491
Number of Sequences: 37866
Number of extensions: 2892691
Number of successful extensions: 63617
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 840
Number of HSP's successfully gapped in prelim test: 1567
Number of HSP's that attempted gapping in prelim test: 13886
Number of HSP's gapped (non-prelim): 16284
length of query: 1941
length of database: 18,247,518
effective HSP length: 117
effective length of query: 1824
effective length of database: 13,817,196
effective search space: 25202565504
effective search space used: 25202565504
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 70 (31.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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