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Search of human proteins with 150378463
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|150378463 MYST histone acetyltransferase (monocytic
leukemia) 3 [Homo sapiens]
(2004 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|150378543 MYST histone acetyltransferase (monocytic leukemia)... 4073 0.0
gi|150378463 MYST histone acetyltransferase (monocytic leukemia)... 4073 0.0
gi|150378493 MYST histone acetyltransferase (monocytic leukemia)... 4073 0.0
gi|100816397 MYST histone acetyltransferase (monocytic leukemia)... 1310 0.0
gi|5901962 MYST histone acetyltransferase 2 [Homo sapiens] 365 e-100
gi|226371636 MYST histone acetyltransferase 1 isoform 1 [Homo sa... 315 2e-85
gi|36287069 K(lysine) acetyltransferase 5 isoform 1 [Homo sapiens] 303 9e-82
gi|36287060 K(lysine) acetyltransferase 5 isoform 3 [Homo sapiens] 303 9e-82
gi|36287049 K(lysine) acetyltransferase 5 isoform 2 [Homo sapiens] 303 9e-82
gi|226371638 MYST histone acetyltransferase 1 isoform 2 [Homo sa... 300 7e-81
gi|205830434 D4, zinc and double PHD fingers family 1 isoform c ... 137 1e-31
gi|205830430 D4, zinc and double PHD fingers family 1 isoform a ... 137 1e-31
gi|5454004 D4, zinc and double PHD fingers family 2 [Homo sapiens] 136 2e-31
gi|205830432 D4, zinc and double PHD fingers family 1 isoform b ... 130 1e-29
gi|194328736 PHD finger protein 10 isoform b [Homo sapiens] 122 3e-27
gi|194328734 PHD finger protein 10 isoform a [Homo sapiens] 122 3e-27
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 91 9e-18
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 90 2e-17
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 89 6e-17
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 87 2e-16
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 87 2e-16
gi|148746195 trichohyalin [Homo sapiens] 86 5e-16
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 86 5e-16
gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens] 85 6e-16
gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens] 85 6e-16
gi|114431236 zinc finger protein 462 [Homo sapiens] 85 8e-16
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens] 84 2e-15
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 83 2e-15
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 83 3e-15
gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapi... 80 2e-14
>gi|150378543 MYST histone acetyltransferase (monocytic leukemia) 3
[Homo sapiens]
Length = 2004
Score = 4073 bits (10562), Expect = 0.0
Identities = 2004/2004 (100%), Positives = 2004/2004 (100%)
Query: 1 MVKLANPLYTEWILEAIKKVKKQKQRPSEERICNAVSSSHGLDRKTVLEQLELSVKDGTI 60
MVKLANPLYTEWILEAIKKVKKQKQRPSEERICNAVSSSHGLDRKTVLEQLELSVKDGTI
Sbjct: 1 MVKLANPLYTEWILEAIKKVKKQKQRPSEERICNAVSSSHGLDRKTVLEQLELSVKDGTI 60
Query: 61 LKVSNKGLNSYKDPDNPGRIALPKPRNHGKLDNKQNVDWNKLIKRAVEGLAESGGSTLKS 120
LKVSNKGLNSYKDPDNPGRIALPKPRNHGKLDNKQNVDWNKLIKRAVEGLAESGGSTLKS
Sbjct: 61 LKVSNKGLNSYKDPDNPGRIALPKPRNHGKLDNKQNVDWNKLIKRAVEGLAESGGSTLKS 120
Query: 121 IERFLKGQKDVSALFGGSAASGFHQQLRLAIKRAIGHGRLLKDGPLYRLNTKATNVDGKE 180
IERFLKGQKDVSALFGGSAASGFHQQLRLAIKRAIGHGRLLKDGPLYRLNTKATNVDGKE
Sbjct: 121 IERFLKGQKDVSALFGGSAASGFHQQLRLAIKRAIGHGRLLKDGPLYRLNTKATNVDGKE 180
Query: 181 SCESLSCLPPVSLLPHEKDKPVAEPIPICSFCLGTKEQNREKKPEELISCADCGNSGHPS 240
SCESLSCLPPVSLLPHEKDKPVAEPIPICSFCLGTKEQNREKKPEELISCADCGNSGHPS
Sbjct: 181 SCESLSCLPPVSLLPHEKDKPVAEPIPICSFCLGTKEQNREKKPEELISCADCGNSGHPS 240
Query: 241 CLKFSPELTVRVKALRWQCIECKTCSSCRDQGKNADNMLFCDSCDRGFHMECCDPPLTRM 300
CLKFSPELTVRVKALRWQCIECKTCSSCRDQGKNADNMLFCDSCDRGFHMECCDPPLTRM
Sbjct: 241 CLKFSPELTVRVKALRWQCIECKTCSSCRDQGKNADNMLFCDSCDRGFHMECCDPPLTRM 300
Query: 301 PKGMWICQICRPRKKGRKLLQKKAAQIKRRYTNPIGRPKNRLKKQNTVSKGPFSKVRTGP 360
PKGMWICQICRPRKKGRKLLQKKAAQIKRRYTNPIGRPKNRLKKQNTVSKGPFSKVRTGP
Sbjct: 301 PKGMWICQICRPRKKGRKLLQKKAAQIKRRYTNPIGRPKNRLKKQNTVSKGPFSKVRTGP 360
Query: 361 GRGRKRKITLSSQSASSSSEEGYLERIDGLDFCRDSNVSLKFNKKTKGLIDGLTKFFTPS 420
GRGRKRKITLSSQSASSSSEEGYLERIDGLDFCRDSNVSLKFNKKTKGLIDGLTKFFTPS
Sbjct: 361 GRGRKRKITLSSQSASSSSEEGYLERIDGLDFCRDSNVSLKFNKKTKGLIDGLTKFFTPS 420
Query: 421 PDGRKARGEVVDYSEQYRIRKRGNRKSSTSDWPTDNQDGWDGKQENEERLFGSQEIMTEK 480
PDGRKARGEVVDYSEQYRIRKRGNRKSSTSDWPTDNQDGWDGKQENEERLFGSQEIMTEK
Sbjct: 421 PDGRKARGEVVDYSEQYRIRKRGNRKSSTSDWPTDNQDGWDGKQENEERLFGSQEIMTEK 480
Query: 481 DMELFRDIQEQALQKVGVTGPPDPQVRCPSVIEFGKYEIHTWYSSPYPQEYSRLPKLYLC 540
DMELFRDIQEQALQKVGVTGPPDPQVRCPSVIEFGKYEIHTWYSSPYPQEYSRLPKLYLC
Sbjct: 481 DMELFRDIQEQALQKVGVTGPPDPQVRCPSVIEFGKYEIHTWYSSPYPQEYSRLPKLYLC 540
Query: 541 EFCLKYMKSRTILQQHMKKCGWFHPPANEIYRKNNISVFEVDGNVSTIYCQNLCLLAKLF 600
EFCLKYMKSRTILQQHMKKCGWFHPPANEIYRKNNISVFEVDGNVSTIYCQNLCLLAKLF
Sbjct: 541 EFCLKYMKSRTILQQHMKKCGWFHPPANEIYRKNNISVFEVDGNVSTIYCQNLCLLAKLF 600
Query: 601 LDHKTLYYDVEPFLFYVLTQNDVKGCHLVGYFSKEKHCQQKYNVSCIMILPQYQRKGYGR 660
LDHKTLYYDVEPFLFYVLTQNDVKGCHLVGYFSKEKHCQQKYNVSCIMILPQYQRKGYGR
Sbjct: 601 LDHKTLYYDVEPFLFYVLTQNDVKGCHLVGYFSKEKHCQQKYNVSCIMILPQYQRKGYGR 660
Query: 661 FLIDFSYLLSKREGQAGSPEKPLSDLGRLSYMAYWKSVILECLYHQNDKQISIKKLSKLT 720
FLIDFSYLLSKREGQAGSPEKPLSDLGRLSYMAYWKSVILECLYHQNDKQISIKKLSKLT
Sbjct: 661 FLIDFSYLLSKREGQAGSPEKPLSDLGRLSYMAYWKSVILECLYHQNDKQISIKKLSKLT 720
Query: 721 GICPQDITSTLHHLRMLDFRSDQFVIIRREKLIQDHMAKLQLNLRPVDVDPECLRWTPVI 780
GICPQDITSTLHHLRMLDFRSDQFVIIRREKLIQDHMAKLQLNLRPVDVDPECLRWTPVI
Sbjct: 721 GICPQDITSTLHHLRMLDFRSDQFVIIRREKLIQDHMAKLQLNLRPVDVDPECLRWTPVI 780
Query: 781 VSNSVVSEEEEEEAEEGENEEPQCQERELEISVGKSVSHENKEQDSYSVESEKKPEVMAP 840
VSNSVVSEEEEEEAEEGENEEPQCQERELEISVGKSVSHENKEQDSYSVESEKKPEVMAP
Sbjct: 781 VSNSVVSEEEEEEAEEGENEEPQCQERELEISVGKSVSHENKEQDSYSVESEKKPEVMAP 840
Query: 841 VSSTRLSKQVLPHDSLPANSQPSRRGRWGRKNRKTQERFGDKDSKLLLEETSSAPQEQYG 900
VSSTRLSKQVLPHDSLPANSQPSRRGRWGRKNRKTQERFGDKDSKLLLEETSSAPQEQYG
Sbjct: 841 VSSTRLSKQVLPHDSLPANSQPSRRGRWGRKNRKTQERFGDKDSKLLLEETSSAPQEQYG 900
Query: 901 ECGEKSEATQEQYTESEEQLVASEEQPSQDGKPDLPKRRLSEGVEPWRGQLKKSPEALKC 960
ECGEKSEATQEQYTESEEQLVASEEQPSQDGKPDLPKRRLSEGVEPWRGQLKKSPEALKC
Sbjct: 901 ECGEKSEATQEQYTESEEQLVASEEQPSQDGKPDLPKRRLSEGVEPWRGQLKKSPEALKC 960
Query: 961 RLTEGSERLPRRYSEGDRAVLRGFSESSEEEEEPESPRSSSPPILTKPTLKRKKPFLHRR 1020
RLTEGSERLPRRYSEGDRAVLRGFSESSEEEEEPESPRSSSPPILTKPTLKRKKPFLHRR
Sbjct: 961 RLTEGSERLPRRYSEGDRAVLRGFSESSEEEEEPESPRSSSPPILTKPTLKRKKPFLHRR 1020
Query: 1021 RRVRKRKHHNSSVVTETISETTEVLDEPFEDSDSERPMPRLEPTFEIDEEEEEEDENELF 1080
RRVRKRKHHNSSVVTETISETTEVLDEPFEDSDSERPMPRLEPTFEIDEEEEEEDENELF
Sbjct: 1021 RRVRKRKHHNSSVVTETISETTEVLDEPFEDSDSERPMPRLEPTFEIDEEEEEEDENELF 1080
Query: 1081 PREYFRRLSSQDVLRCQSSSKRKSKDEEEDEESDDADDTPILKPVSLLRKRDVKNSPLEP 1140
PREYFRRLSSQDVLRCQSSSKRKSKDEEEDEESDDADDTPILKPVSLLRKRDVKNSPLEP
Sbjct: 1081 PREYFRRLSSQDVLRCQSSSKRKSKDEEEDEESDDADDTPILKPVSLLRKRDVKNSPLEP 1140
Query: 1141 DTSTPLKKKKGWPKGKSRKPIHWKKRPGRKPGFKLSREIMPVSTQACVIEPIVSIPKAGR 1200
DTSTPLKKKKGWPKGKSRKPIHWKKRPGRKPGFKLSREIMPVSTQACVIEPIVSIPKAGR
Sbjct: 1141 DTSTPLKKKKGWPKGKSRKPIHWKKRPGRKPGFKLSREIMPVSTQACVIEPIVSIPKAGR 1200
Query: 1201 KPKIQESEETVEPKEDMPLPEERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSNS 1260
KPKIQESEETVEPKEDMPLPEERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSNS
Sbjct: 1201 KPKIQESEETVEPKEDMPLPEERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSNS 1260
Query: 1261 PETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDED 1320
PETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDED
Sbjct: 1261 PETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDED 1320
Query: 1321 DGHLESTKKKELEEQPTREDVKEEPGVQESFLDANMQKSREKIKDKEETELDSEEEQPSH 1380
DGHLESTKKKELEEQPTREDVKEEPGVQESFLDANMQKSREKIKDKEETELDSEEEQPSH
Sbjct: 1321 DGHLESTKKKELEEQPTREDVKEEPGVQESFLDANMQKSREKIKDKEETELDSEEEQPSH 1380
Query: 1381 DTSVVSEQMAGSEDDHEEDSHTKEELIELKEEEEIPHSELDLETVQAVQSLTQEESSEHE 1440
DTSVVSEQMAGSEDDHEEDSHTKEELIELKEEEEIPHSELDLETVQAVQSLTQEESSEHE
Sbjct: 1381 DTSVVSEQMAGSEDDHEEDSHTKEELIELKEEEEIPHSELDLETVQAVQSLTQEESSEHE 1440
Query: 1441 GAYQDCEETLAACQTLQSYTQADEDPQMSMVEDCHASEHNSPISSVQSHPSQSVRSVSSP 1500
GAYQDCEETLAACQTLQSYTQADEDPQMSMVEDCHASEHNSPISSVQSHPSQSVRSVSSP
Sbjct: 1441 GAYQDCEETLAACQTLQSYTQADEDPQMSMVEDCHASEHNSPISSVQSHPSQSVRSVSSP 1500
Query: 1501 NVPALESGYTQISPEQGSLSAPSMQNMETSPMMDVPSVSDHSQQVVDSGFSDLGSIESTT 1560
NVPALESGYTQISPEQGSLSAPSMQNMETSPMMDVPSVSDHSQQVVDSGFSDLGSIESTT
Sbjct: 1501 NVPALESGYTQISPEQGSLSAPSMQNMETSPMMDVPSVSDHSQQVVDSGFSDLGSIESTT 1560
Query: 1561 ENYENPSSYDSTMGGSICGNSSSQSSCSYGGLSSSSSLTQSSCVVTQQMASMGSSCSMMQ 1620
ENYENPSSYDSTMGGSICGNSSSQSSCSYGGLSSSSSLTQSSCVVTQQMASMGSSCSMMQ
Sbjct: 1561 ENYENPSSYDSTMGGSICGNSSSQSSCSYGGLSSSSSLTQSSCVVTQQMASMGSSCSMMQ 1620
Query: 1621 QSSVQPAANCSIKSPQSCVVERPPSNQQQQPPPPPPQQPQPPPPQPQPAPQPPPPQQQPQ 1680
QSSVQPAANCSIKSPQSCVVERPPSNQQQQPPPPPPQQPQPPPPQPQPAPQPPPPQQQPQ
Sbjct: 1621 QSSVQPAANCSIKSPQSCVVERPPSNQQQQPPPPPPQQPQPPPPQPQPAPQPPPPQQQPQ 1680
Query: 1681 QQPQPQPQQPPPPPPPQQQPPLSQCSMNNSFTPAPMIMEIPESGSTGNISIYERIPGDFG 1740
QQPQPQPQQPPPPPPPQQQPPLSQCSMNNSFTPAPMIMEIPESGSTGNISIYERIPGDFG
Sbjct: 1681 QQPQPQPQQPPPPPPPQQQPPLSQCSMNNSFTPAPMIMEIPESGSTGNISIYERIPGDFG 1740
Query: 1741 AGSYSQPSATFSLAKLQQLTNTIMDPHAMPYSHSPAVTSYATSVSLSNTGLAQLAPSHPL 1800
AGSYSQPSATFSLAKLQQLTNTIMDPHAMPYSHSPAVTSYATSVSLSNTGLAQLAPSHPL
Sbjct: 1741 AGSYSQPSATFSLAKLQQLTNTIMDPHAMPYSHSPAVTSYATSVSLSNTGLAQLAPSHPL 1800
Query: 1801 AGTPQAQATMTPPPNLASTTMNLTSPLLQCNMSATNIGIPHTQRLQGQMPVKGHISIRSK 1860
AGTPQAQATMTPPPNLASTTMNLTSPLLQCNMSATNIGIPHTQRLQGQMPVKGHISIRSK
Sbjct: 1801 AGTPQAQATMTPPPNLASTTMNLTSPLLQCNMSATNIGIPHTQRLQGQMPVKGHISIRSK 1860
Query: 1861 SAPLPSAAAHQQQLYGRSPSAVAMQAGPRALAVQRGMNMGVNLMPTPAYNVNSMNMNTLN 1920
SAPLPSAAAHQQQLYGRSPSAVAMQAGPRALAVQRGMNMGVNLMPTPAYNVNSMNMNTLN
Sbjct: 1861 SAPLPSAAAHQQQLYGRSPSAVAMQAGPRALAVQRGMNMGVNLMPTPAYNVNSMNMNTLN 1920
Query: 1921 AMNSYRMTQPMMNSSYHSNPAYMNQTAQYPMQMQMGMMGSQAYTQQPMQPNPHGNMMYTG 1980
AMNSYRMTQPMMNSSYHSNPAYMNQTAQYPMQMQMGMMGSQAYTQQPMQPNPHGNMMYTG
Sbjct: 1921 AMNSYRMTQPMMNSSYHSNPAYMNQTAQYPMQMQMGMMGSQAYTQQPMQPNPHGNMMYTG 1980
Query: 1981 PSHHSYMNAAGVPKQSLNGPYMRR 2004
PSHHSYMNAAGVPKQSLNGPYMRR
Sbjct: 1981 PSHHSYMNAAGVPKQSLNGPYMRR 2004
>gi|150378463 MYST histone acetyltransferase (monocytic leukemia) 3
[Homo sapiens]
Length = 2004
Score = 4073 bits (10562), Expect = 0.0
Identities = 2004/2004 (100%), Positives = 2004/2004 (100%)
Query: 1 MVKLANPLYTEWILEAIKKVKKQKQRPSEERICNAVSSSHGLDRKTVLEQLELSVKDGTI 60
MVKLANPLYTEWILEAIKKVKKQKQRPSEERICNAVSSSHGLDRKTVLEQLELSVKDGTI
Sbjct: 1 MVKLANPLYTEWILEAIKKVKKQKQRPSEERICNAVSSSHGLDRKTVLEQLELSVKDGTI 60
Query: 61 LKVSNKGLNSYKDPDNPGRIALPKPRNHGKLDNKQNVDWNKLIKRAVEGLAESGGSTLKS 120
LKVSNKGLNSYKDPDNPGRIALPKPRNHGKLDNKQNVDWNKLIKRAVEGLAESGGSTLKS
Sbjct: 61 LKVSNKGLNSYKDPDNPGRIALPKPRNHGKLDNKQNVDWNKLIKRAVEGLAESGGSTLKS 120
Query: 121 IERFLKGQKDVSALFGGSAASGFHQQLRLAIKRAIGHGRLLKDGPLYRLNTKATNVDGKE 180
IERFLKGQKDVSALFGGSAASGFHQQLRLAIKRAIGHGRLLKDGPLYRLNTKATNVDGKE
Sbjct: 121 IERFLKGQKDVSALFGGSAASGFHQQLRLAIKRAIGHGRLLKDGPLYRLNTKATNVDGKE 180
Query: 181 SCESLSCLPPVSLLPHEKDKPVAEPIPICSFCLGTKEQNREKKPEELISCADCGNSGHPS 240
SCESLSCLPPVSLLPHEKDKPVAEPIPICSFCLGTKEQNREKKPEELISCADCGNSGHPS
Sbjct: 181 SCESLSCLPPVSLLPHEKDKPVAEPIPICSFCLGTKEQNREKKPEELISCADCGNSGHPS 240
Query: 241 CLKFSPELTVRVKALRWQCIECKTCSSCRDQGKNADNMLFCDSCDRGFHMECCDPPLTRM 300
CLKFSPELTVRVKALRWQCIECKTCSSCRDQGKNADNMLFCDSCDRGFHMECCDPPLTRM
Sbjct: 241 CLKFSPELTVRVKALRWQCIECKTCSSCRDQGKNADNMLFCDSCDRGFHMECCDPPLTRM 300
Query: 301 PKGMWICQICRPRKKGRKLLQKKAAQIKRRYTNPIGRPKNRLKKQNTVSKGPFSKVRTGP 360
PKGMWICQICRPRKKGRKLLQKKAAQIKRRYTNPIGRPKNRLKKQNTVSKGPFSKVRTGP
Sbjct: 301 PKGMWICQICRPRKKGRKLLQKKAAQIKRRYTNPIGRPKNRLKKQNTVSKGPFSKVRTGP 360
Query: 361 GRGRKRKITLSSQSASSSSEEGYLERIDGLDFCRDSNVSLKFNKKTKGLIDGLTKFFTPS 420
GRGRKRKITLSSQSASSSSEEGYLERIDGLDFCRDSNVSLKFNKKTKGLIDGLTKFFTPS
Sbjct: 361 GRGRKRKITLSSQSASSSSEEGYLERIDGLDFCRDSNVSLKFNKKTKGLIDGLTKFFTPS 420
Query: 421 PDGRKARGEVVDYSEQYRIRKRGNRKSSTSDWPTDNQDGWDGKQENEERLFGSQEIMTEK 480
PDGRKARGEVVDYSEQYRIRKRGNRKSSTSDWPTDNQDGWDGKQENEERLFGSQEIMTEK
Sbjct: 421 PDGRKARGEVVDYSEQYRIRKRGNRKSSTSDWPTDNQDGWDGKQENEERLFGSQEIMTEK 480
Query: 481 DMELFRDIQEQALQKVGVTGPPDPQVRCPSVIEFGKYEIHTWYSSPYPQEYSRLPKLYLC 540
DMELFRDIQEQALQKVGVTGPPDPQVRCPSVIEFGKYEIHTWYSSPYPQEYSRLPKLYLC
Sbjct: 481 DMELFRDIQEQALQKVGVTGPPDPQVRCPSVIEFGKYEIHTWYSSPYPQEYSRLPKLYLC 540
Query: 541 EFCLKYMKSRTILQQHMKKCGWFHPPANEIYRKNNISVFEVDGNVSTIYCQNLCLLAKLF 600
EFCLKYMKSRTILQQHMKKCGWFHPPANEIYRKNNISVFEVDGNVSTIYCQNLCLLAKLF
Sbjct: 541 EFCLKYMKSRTILQQHMKKCGWFHPPANEIYRKNNISVFEVDGNVSTIYCQNLCLLAKLF 600
Query: 601 LDHKTLYYDVEPFLFYVLTQNDVKGCHLVGYFSKEKHCQQKYNVSCIMILPQYQRKGYGR 660
LDHKTLYYDVEPFLFYVLTQNDVKGCHLVGYFSKEKHCQQKYNVSCIMILPQYQRKGYGR
Sbjct: 601 LDHKTLYYDVEPFLFYVLTQNDVKGCHLVGYFSKEKHCQQKYNVSCIMILPQYQRKGYGR 660
Query: 661 FLIDFSYLLSKREGQAGSPEKPLSDLGRLSYMAYWKSVILECLYHQNDKQISIKKLSKLT 720
FLIDFSYLLSKREGQAGSPEKPLSDLGRLSYMAYWKSVILECLYHQNDKQISIKKLSKLT
Sbjct: 661 FLIDFSYLLSKREGQAGSPEKPLSDLGRLSYMAYWKSVILECLYHQNDKQISIKKLSKLT 720
Query: 721 GICPQDITSTLHHLRMLDFRSDQFVIIRREKLIQDHMAKLQLNLRPVDVDPECLRWTPVI 780
GICPQDITSTLHHLRMLDFRSDQFVIIRREKLIQDHMAKLQLNLRPVDVDPECLRWTPVI
Sbjct: 721 GICPQDITSTLHHLRMLDFRSDQFVIIRREKLIQDHMAKLQLNLRPVDVDPECLRWTPVI 780
Query: 781 VSNSVVSEEEEEEAEEGENEEPQCQERELEISVGKSVSHENKEQDSYSVESEKKPEVMAP 840
VSNSVVSEEEEEEAEEGENEEPQCQERELEISVGKSVSHENKEQDSYSVESEKKPEVMAP
Sbjct: 781 VSNSVVSEEEEEEAEEGENEEPQCQERELEISVGKSVSHENKEQDSYSVESEKKPEVMAP 840
Query: 841 VSSTRLSKQVLPHDSLPANSQPSRRGRWGRKNRKTQERFGDKDSKLLLEETSSAPQEQYG 900
VSSTRLSKQVLPHDSLPANSQPSRRGRWGRKNRKTQERFGDKDSKLLLEETSSAPQEQYG
Sbjct: 841 VSSTRLSKQVLPHDSLPANSQPSRRGRWGRKNRKTQERFGDKDSKLLLEETSSAPQEQYG 900
Query: 901 ECGEKSEATQEQYTESEEQLVASEEQPSQDGKPDLPKRRLSEGVEPWRGQLKKSPEALKC 960
ECGEKSEATQEQYTESEEQLVASEEQPSQDGKPDLPKRRLSEGVEPWRGQLKKSPEALKC
Sbjct: 901 ECGEKSEATQEQYTESEEQLVASEEQPSQDGKPDLPKRRLSEGVEPWRGQLKKSPEALKC 960
Query: 961 RLTEGSERLPRRYSEGDRAVLRGFSESSEEEEEPESPRSSSPPILTKPTLKRKKPFLHRR 1020
RLTEGSERLPRRYSEGDRAVLRGFSESSEEEEEPESPRSSSPPILTKPTLKRKKPFLHRR
Sbjct: 961 RLTEGSERLPRRYSEGDRAVLRGFSESSEEEEEPESPRSSSPPILTKPTLKRKKPFLHRR 1020
Query: 1021 RRVRKRKHHNSSVVTETISETTEVLDEPFEDSDSERPMPRLEPTFEIDEEEEEEDENELF 1080
RRVRKRKHHNSSVVTETISETTEVLDEPFEDSDSERPMPRLEPTFEIDEEEEEEDENELF
Sbjct: 1021 RRVRKRKHHNSSVVTETISETTEVLDEPFEDSDSERPMPRLEPTFEIDEEEEEEDENELF 1080
Query: 1081 PREYFRRLSSQDVLRCQSSSKRKSKDEEEDEESDDADDTPILKPVSLLRKRDVKNSPLEP 1140
PREYFRRLSSQDVLRCQSSSKRKSKDEEEDEESDDADDTPILKPVSLLRKRDVKNSPLEP
Sbjct: 1081 PREYFRRLSSQDVLRCQSSSKRKSKDEEEDEESDDADDTPILKPVSLLRKRDVKNSPLEP 1140
Query: 1141 DTSTPLKKKKGWPKGKSRKPIHWKKRPGRKPGFKLSREIMPVSTQACVIEPIVSIPKAGR 1200
DTSTPLKKKKGWPKGKSRKPIHWKKRPGRKPGFKLSREIMPVSTQACVIEPIVSIPKAGR
Sbjct: 1141 DTSTPLKKKKGWPKGKSRKPIHWKKRPGRKPGFKLSREIMPVSTQACVIEPIVSIPKAGR 1200
Query: 1201 KPKIQESEETVEPKEDMPLPEERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSNS 1260
KPKIQESEETVEPKEDMPLPEERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSNS
Sbjct: 1201 KPKIQESEETVEPKEDMPLPEERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSNS 1260
Query: 1261 PETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDED 1320
PETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDED
Sbjct: 1261 PETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDED 1320
Query: 1321 DGHLESTKKKELEEQPTREDVKEEPGVQESFLDANMQKSREKIKDKEETELDSEEEQPSH 1380
DGHLESTKKKELEEQPTREDVKEEPGVQESFLDANMQKSREKIKDKEETELDSEEEQPSH
Sbjct: 1321 DGHLESTKKKELEEQPTREDVKEEPGVQESFLDANMQKSREKIKDKEETELDSEEEQPSH 1380
Query: 1381 DTSVVSEQMAGSEDDHEEDSHTKEELIELKEEEEIPHSELDLETVQAVQSLTQEESSEHE 1440
DTSVVSEQMAGSEDDHEEDSHTKEELIELKEEEEIPHSELDLETVQAVQSLTQEESSEHE
Sbjct: 1381 DTSVVSEQMAGSEDDHEEDSHTKEELIELKEEEEIPHSELDLETVQAVQSLTQEESSEHE 1440
Query: 1441 GAYQDCEETLAACQTLQSYTQADEDPQMSMVEDCHASEHNSPISSVQSHPSQSVRSVSSP 1500
GAYQDCEETLAACQTLQSYTQADEDPQMSMVEDCHASEHNSPISSVQSHPSQSVRSVSSP
Sbjct: 1441 GAYQDCEETLAACQTLQSYTQADEDPQMSMVEDCHASEHNSPISSVQSHPSQSVRSVSSP 1500
Query: 1501 NVPALESGYTQISPEQGSLSAPSMQNMETSPMMDVPSVSDHSQQVVDSGFSDLGSIESTT 1560
NVPALESGYTQISPEQGSLSAPSMQNMETSPMMDVPSVSDHSQQVVDSGFSDLGSIESTT
Sbjct: 1501 NVPALESGYTQISPEQGSLSAPSMQNMETSPMMDVPSVSDHSQQVVDSGFSDLGSIESTT 1560
Query: 1561 ENYENPSSYDSTMGGSICGNSSSQSSCSYGGLSSSSSLTQSSCVVTQQMASMGSSCSMMQ 1620
ENYENPSSYDSTMGGSICGNSSSQSSCSYGGLSSSSSLTQSSCVVTQQMASMGSSCSMMQ
Sbjct: 1561 ENYENPSSYDSTMGGSICGNSSSQSSCSYGGLSSSSSLTQSSCVVTQQMASMGSSCSMMQ 1620
Query: 1621 QSSVQPAANCSIKSPQSCVVERPPSNQQQQPPPPPPQQPQPPPPQPQPAPQPPPPQQQPQ 1680
QSSVQPAANCSIKSPQSCVVERPPSNQQQQPPPPPPQQPQPPPPQPQPAPQPPPPQQQPQ
Sbjct: 1621 QSSVQPAANCSIKSPQSCVVERPPSNQQQQPPPPPPQQPQPPPPQPQPAPQPPPPQQQPQ 1680
Query: 1681 QQPQPQPQQPPPPPPPQQQPPLSQCSMNNSFTPAPMIMEIPESGSTGNISIYERIPGDFG 1740
QQPQPQPQQPPPPPPPQQQPPLSQCSMNNSFTPAPMIMEIPESGSTGNISIYERIPGDFG
Sbjct: 1681 QQPQPQPQQPPPPPPPQQQPPLSQCSMNNSFTPAPMIMEIPESGSTGNISIYERIPGDFG 1740
Query: 1741 AGSYSQPSATFSLAKLQQLTNTIMDPHAMPYSHSPAVTSYATSVSLSNTGLAQLAPSHPL 1800
AGSYSQPSATFSLAKLQQLTNTIMDPHAMPYSHSPAVTSYATSVSLSNTGLAQLAPSHPL
Sbjct: 1741 AGSYSQPSATFSLAKLQQLTNTIMDPHAMPYSHSPAVTSYATSVSLSNTGLAQLAPSHPL 1800
Query: 1801 AGTPQAQATMTPPPNLASTTMNLTSPLLQCNMSATNIGIPHTQRLQGQMPVKGHISIRSK 1860
AGTPQAQATMTPPPNLASTTMNLTSPLLQCNMSATNIGIPHTQRLQGQMPVKGHISIRSK
Sbjct: 1801 AGTPQAQATMTPPPNLASTTMNLTSPLLQCNMSATNIGIPHTQRLQGQMPVKGHISIRSK 1860
Query: 1861 SAPLPSAAAHQQQLYGRSPSAVAMQAGPRALAVQRGMNMGVNLMPTPAYNVNSMNMNTLN 1920
SAPLPSAAAHQQQLYGRSPSAVAMQAGPRALAVQRGMNMGVNLMPTPAYNVNSMNMNTLN
Sbjct: 1861 SAPLPSAAAHQQQLYGRSPSAVAMQAGPRALAVQRGMNMGVNLMPTPAYNVNSMNMNTLN 1920
Query: 1921 AMNSYRMTQPMMNSSYHSNPAYMNQTAQYPMQMQMGMMGSQAYTQQPMQPNPHGNMMYTG 1980
AMNSYRMTQPMMNSSYHSNPAYMNQTAQYPMQMQMGMMGSQAYTQQPMQPNPHGNMMYTG
Sbjct: 1921 AMNSYRMTQPMMNSSYHSNPAYMNQTAQYPMQMQMGMMGSQAYTQQPMQPNPHGNMMYTG 1980
Query: 1981 PSHHSYMNAAGVPKQSLNGPYMRR 2004
PSHHSYMNAAGVPKQSLNGPYMRR
Sbjct: 1981 PSHHSYMNAAGVPKQSLNGPYMRR 2004
>gi|150378493 MYST histone acetyltransferase (monocytic leukemia) 3
[Homo sapiens]
Length = 2004
Score = 4073 bits (10562), Expect = 0.0
Identities = 2004/2004 (100%), Positives = 2004/2004 (100%)
Query: 1 MVKLANPLYTEWILEAIKKVKKQKQRPSEERICNAVSSSHGLDRKTVLEQLELSVKDGTI 60
MVKLANPLYTEWILEAIKKVKKQKQRPSEERICNAVSSSHGLDRKTVLEQLELSVKDGTI
Sbjct: 1 MVKLANPLYTEWILEAIKKVKKQKQRPSEERICNAVSSSHGLDRKTVLEQLELSVKDGTI 60
Query: 61 LKVSNKGLNSYKDPDNPGRIALPKPRNHGKLDNKQNVDWNKLIKRAVEGLAESGGSTLKS 120
LKVSNKGLNSYKDPDNPGRIALPKPRNHGKLDNKQNVDWNKLIKRAVEGLAESGGSTLKS
Sbjct: 61 LKVSNKGLNSYKDPDNPGRIALPKPRNHGKLDNKQNVDWNKLIKRAVEGLAESGGSTLKS 120
Query: 121 IERFLKGQKDVSALFGGSAASGFHQQLRLAIKRAIGHGRLLKDGPLYRLNTKATNVDGKE 180
IERFLKGQKDVSALFGGSAASGFHQQLRLAIKRAIGHGRLLKDGPLYRLNTKATNVDGKE
Sbjct: 121 IERFLKGQKDVSALFGGSAASGFHQQLRLAIKRAIGHGRLLKDGPLYRLNTKATNVDGKE 180
Query: 181 SCESLSCLPPVSLLPHEKDKPVAEPIPICSFCLGTKEQNREKKPEELISCADCGNSGHPS 240
SCESLSCLPPVSLLPHEKDKPVAEPIPICSFCLGTKEQNREKKPEELISCADCGNSGHPS
Sbjct: 181 SCESLSCLPPVSLLPHEKDKPVAEPIPICSFCLGTKEQNREKKPEELISCADCGNSGHPS 240
Query: 241 CLKFSPELTVRVKALRWQCIECKTCSSCRDQGKNADNMLFCDSCDRGFHMECCDPPLTRM 300
CLKFSPELTVRVKALRWQCIECKTCSSCRDQGKNADNMLFCDSCDRGFHMECCDPPLTRM
Sbjct: 241 CLKFSPELTVRVKALRWQCIECKTCSSCRDQGKNADNMLFCDSCDRGFHMECCDPPLTRM 300
Query: 301 PKGMWICQICRPRKKGRKLLQKKAAQIKRRYTNPIGRPKNRLKKQNTVSKGPFSKVRTGP 360
PKGMWICQICRPRKKGRKLLQKKAAQIKRRYTNPIGRPKNRLKKQNTVSKGPFSKVRTGP
Sbjct: 301 PKGMWICQICRPRKKGRKLLQKKAAQIKRRYTNPIGRPKNRLKKQNTVSKGPFSKVRTGP 360
Query: 361 GRGRKRKITLSSQSASSSSEEGYLERIDGLDFCRDSNVSLKFNKKTKGLIDGLTKFFTPS 420
GRGRKRKITLSSQSASSSSEEGYLERIDGLDFCRDSNVSLKFNKKTKGLIDGLTKFFTPS
Sbjct: 361 GRGRKRKITLSSQSASSSSEEGYLERIDGLDFCRDSNVSLKFNKKTKGLIDGLTKFFTPS 420
Query: 421 PDGRKARGEVVDYSEQYRIRKRGNRKSSTSDWPTDNQDGWDGKQENEERLFGSQEIMTEK 480
PDGRKARGEVVDYSEQYRIRKRGNRKSSTSDWPTDNQDGWDGKQENEERLFGSQEIMTEK
Sbjct: 421 PDGRKARGEVVDYSEQYRIRKRGNRKSSTSDWPTDNQDGWDGKQENEERLFGSQEIMTEK 480
Query: 481 DMELFRDIQEQALQKVGVTGPPDPQVRCPSVIEFGKYEIHTWYSSPYPQEYSRLPKLYLC 540
DMELFRDIQEQALQKVGVTGPPDPQVRCPSVIEFGKYEIHTWYSSPYPQEYSRLPKLYLC
Sbjct: 481 DMELFRDIQEQALQKVGVTGPPDPQVRCPSVIEFGKYEIHTWYSSPYPQEYSRLPKLYLC 540
Query: 541 EFCLKYMKSRTILQQHMKKCGWFHPPANEIYRKNNISVFEVDGNVSTIYCQNLCLLAKLF 600
EFCLKYMKSRTILQQHMKKCGWFHPPANEIYRKNNISVFEVDGNVSTIYCQNLCLLAKLF
Sbjct: 541 EFCLKYMKSRTILQQHMKKCGWFHPPANEIYRKNNISVFEVDGNVSTIYCQNLCLLAKLF 600
Query: 601 LDHKTLYYDVEPFLFYVLTQNDVKGCHLVGYFSKEKHCQQKYNVSCIMILPQYQRKGYGR 660
LDHKTLYYDVEPFLFYVLTQNDVKGCHLVGYFSKEKHCQQKYNVSCIMILPQYQRKGYGR
Sbjct: 601 LDHKTLYYDVEPFLFYVLTQNDVKGCHLVGYFSKEKHCQQKYNVSCIMILPQYQRKGYGR 660
Query: 661 FLIDFSYLLSKREGQAGSPEKPLSDLGRLSYMAYWKSVILECLYHQNDKQISIKKLSKLT 720
FLIDFSYLLSKREGQAGSPEKPLSDLGRLSYMAYWKSVILECLYHQNDKQISIKKLSKLT
Sbjct: 661 FLIDFSYLLSKREGQAGSPEKPLSDLGRLSYMAYWKSVILECLYHQNDKQISIKKLSKLT 720
Query: 721 GICPQDITSTLHHLRMLDFRSDQFVIIRREKLIQDHMAKLQLNLRPVDVDPECLRWTPVI 780
GICPQDITSTLHHLRMLDFRSDQFVIIRREKLIQDHMAKLQLNLRPVDVDPECLRWTPVI
Sbjct: 721 GICPQDITSTLHHLRMLDFRSDQFVIIRREKLIQDHMAKLQLNLRPVDVDPECLRWTPVI 780
Query: 781 VSNSVVSEEEEEEAEEGENEEPQCQERELEISVGKSVSHENKEQDSYSVESEKKPEVMAP 840
VSNSVVSEEEEEEAEEGENEEPQCQERELEISVGKSVSHENKEQDSYSVESEKKPEVMAP
Sbjct: 781 VSNSVVSEEEEEEAEEGENEEPQCQERELEISVGKSVSHENKEQDSYSVESEKKPEVMAP 840
Query: 841 VSSTRLSKQVLPHDSLPANSQPSRRGRWGRKNRKTQERFGDKDSKLLLEETSSAPQEQYG 900
VSSTRLSKQVLPHDSLPANSQPSRRGRWGRKNRKTQERFGDKDSKLLLEETSSAPQEQYG
Sbjct: 841 VSSTRLSKQVLPHDSLPANSQPSRRGRWGRKNRKTQERFGDKDSKLLLEETSSAPQEQYG 900
Query: 901 ECGEKSEATQEQYTESEEQLVASEEQPSQDGKPDLPKRRLSEGVEPWRGQLKKSPEALKC 960
ECGEKSEATQEQYTESEEQLVASEEQPSQDGKPDLPKRRLSEGVEPWRGQLKKSPEALKC
Sbjct: 901 ECGEKSEATQEQYTESEEQLVASEEQPSQDGKPDLPKRRLSEGVEPWRGQLKKSPEALKC 960
Query: 961 RLTEGSERLPRRYSEGDRAVLRGFSESSEEEEEPESPRSSSPPILTKPTLKRKKPFLHRR 1020
RLTEGSERLPRRYSEGDRAVLRGFSESSEEEEEPESPRSSSPPILTKPTLKRKKPFLHRR
Sbjct: 961 RLTEGSERLPRRYSEGDRAVLRGFSESSEEEEEPESPRSSSPPILTKPTLKRKKPFLHRR 1020
Query: 1021 RRVRKRKHHNSSVVTETISETTEVLDEPFEDSDSERPMPRLEPTFEIDEEEEEEDENELF 1080
RRVRKRKHHNSSVVTETISETTEVLDEPFEDSDSERPMPRLEPTFEIDEEEEEEDENELF
Sbjct: 1021 RRVRKRKHHNSSVVTETISETTEVLDEPFEDSDSERPMPRLEPTFEIDEEEEEEDENELF 1080
Query: 1081 PREYFRRLSSQDVLRCQSSSKRKSKDEEEDEESDDADDTPILKPVSLLRKRDVKNSPLEP 1140
PREYFRRLSSQDVLRCQSSSKRKSKDEEEDEESDDADDTPILKPVSLLRKRDVKNSPLEP
Sbjct: 1081 PREYFRRLSSQDVLRCQSSSKRKSKDEEEDEESDDADDTPILKPVSLLRKRDVKNSPLEP 1140
Query: 1141 DTSTPLKKKKGWPKGKSRKPIHWKKRPGRKPGFKLSREIMPVSTQACVIEPIVSIPKAGR 1200
DTSTPLKKKKGWPKGKSRKPIHWKKRPGRKPGFKLSREIMPVSTQACVIEPIVSIPKAGR
Sbjct: 1141 DTSTPLKKKKGWPKGKSRKPIHWKKRPGRKPGFKLSREIMPVSTQACVIEPIVSIPKAGR 1200
Query: 1201 KPKIQESEETVEPKEDMPLPEERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSNS 1260
KPKIQESEETVEPKEDMPLPEERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSNS
Sbjct: 1201 KPKIQESEETVEPKEDMPLPEERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSNS 1260
Query: 1261 PETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDED 1320
PETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDED
Sbjct: 1261 PETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDED 1320
Query: 1321 DGHLESTKKKELEEQPTREDVKEEPGVQESFLDANMQKSREKIKDKEETELDSEEEQPSH 1380
DGHLESTKKKELEEQPTREDVKEEPGVQESFLDANMQKSREKIKDKEETELDSEEEQPSH
Sbjct: 1321 DGHLESTKKKELEEQPTREDVKEEPGVQESFLDANMQKSREKIKDKEETELDSEEEQPSH 1380
Query: 1381 DTSVVSEQMAGSEDDHEEDSHTKEELIELKEEEEIPHSELDLETVQAVQSLTQEESSEHE 1440
DTSVVSEQMAGSEDDHEEDSHTKEELIELKEEEEIPHSELDLETVQAVQSLTQEESSEHE
Sbjct: 1381 DTSVVSEQMAGSEDDHEEDSHTKEELIELKEEEEIPHSELDLETVQAVQSLTQEESSEHE 1440
Query: 1441 GAYQDCEETLAACQTLQSYTQADEDPQMSMVEDCHASEHNSPISSVQSHPSQSVRSVSSP 1500
GAYQDCEETLAACQTLQSYTQADEDPQMSMVEDCHASEHNSPISSVQSHPSQSVRSVSSP
Sbjct: 1441 GAYQDCEETLAACQTLQSYTQADEDPQMSMVEDCHASEHNSPISSVQSHPSQSVRSVSSP 1500
Query: 1501 NVPALESGYTQISPEQGSLSAPSMQNMETSPMMDVPSVSDHSQQVVDSGFSDLGSIESTT 1560
NVPALESGYTQISPEQGSLSAPSMQNMETSPMMDVPSVSDHSQQVVDSGFSDLGSIESTT
Sbjct: 1501 NVPALESGYTQISPEQGSLSAPSMQNMETSPMMDVPSVSDHSQQVVDSGFSDLGSIESTT 1560
Query: 1561 ENYENPSSYDSTMGGSICGNSSSQSSCSYGGLSSSSSLTQSSCVVTQQMASMGSSCSMMQ 1620
ENYENPSSYDSTMGGSICGNSSSQSSCSYGGLSSSSSLTQSSCVVTQQMASMGSSCSMMQ
Sbjct: 1561 ENYENPSSYDSTMGGSICGNSSSQSSCSYGGLSSSSSLTQSSCVVTQQMASMGSSCSMMQ 1620
Query: 1621 QSSVQPAANCSIKSPQSCVVERPPSNQQQQPPPPPPQQPQPPPPQPQPAPQPPPPQQQPQ 1680
QSSVQPAANCSIKSPQSCVVERPPSNQQQQPPPPPPQQPQPPPPQPQPAPQPPPPQQQPQ
Sbjct: 1621 QSSVQPAANCSIKSPQSCVVERPPSNQQQQPPPPPPQQPQPPPPQPQPAPQPPPPQQQPQ 1680
Query: 1681 QQPQPQPQQPPPPPPPQQQPPLSQCSMNNSFTPAPMIMEIPESGSTGNISIYERIPGDFG 1740
QQPQPQPQQPPPPPPPQQQPPLSQCSMNNSFTPAPMIMEIPESGSTGNISIYERIPGDFG
Sbjct: 1681 QQPQPQPQQPPPPPPPQQQPPLSQCSMNNSFTPAPMIMEIPESGSTGNISIYERIPGDFG 1740
Query: 1741 AGSYSQPSATFSLAKLQQLTNTIMDPHAMPYSHSPAVTSYATSVSLSNTGLAQLAPSHPL 1800
AGSYSQPSATFSLAKLQQLTNTIMDPHAMPYSHSPAVTSYATSVSLSNTGLAQLAPSHPL
Sbjct: 1741 AGSYSQPSATFSLAKLQQLTNTIMDPHAMPYSHSPAVTSYATSVSLSNTGLAQLAPSHPL 1800
Query: 1801 AGTPQAQATMTPPPNLASTTMNLTSPLLQCNMSATNIGIPHTQRLQGQMPVKGHISIRSK 1860
AGTPQAQATMTPPPNLASTTMNLTSPLLQCNMSATNIGIPHTQRLQGQMPVKGHISIRSK
Sbjct: 1801 AGTPQAQATMTPPPNLASTTMNLTSPLLQCNMSATNIGIPHTQRLQGQMPVKGHISIRSK 1860
Query: 1861 SAPLPSAAAHQQQLYGRSPSAVAMQAGPRALAVQRGMNMGVNLMPTPAYNVNSMNMNTLN 1920
SAPLPSAAAHQQQLYGRSPSAVAMQAGPRALAVQRGMNMGVNLMPTPAYNVNSMNMNTLN
Sbjct: 1861 SAPLPSAAAHQQQLYGRSPSAVAMQAGPRALAVQRGMNMGVNLMPTPAYNVNSMNMNTLN 1920
Query: 1921 AMNSYRMTQPMMNSSYHSNPAYMNQTAQYPMQMQMGMMGSQAYTQQPMQPNPHGNMMYTG 1980
AMNSYRMTQPMMNSSYHSNPAYMNQTAQYPMQMQMGMMGSQAYTQQPMQPNPHGNMMYTG
Sbjct: 1921 AMNSYRMTQPMMNSSYHSNPAYMNQTAQYPMQMQMGMMGSQAYTQQPMQPNPHGNMMYTG 1980
Query: 1981 PSHHSYMNAAGVPKQSLNGPYMRR 2004
PSHHSYMNAAGVPKQSLNGPYMRR
Sbjct: 1981 PSHHSYMNAAGVPKQSLNGPYMRR 2004
>gi|100816397 MYST histone acetyltransferase (monocytic leukemia) 4
[Homo sapiens]
Length = 2073
Score = 1310 bits (3390), Expect = 0.0
Identities = 780/1596 (48%), Positives = 969/1596 (60%), Gaps = 249/1596 (15%)
Query: 463 KQENEE-RLFGSQEIMTEKDMELFRDIQEQALQKVGVTGPPDPQVRCPSVIEFGKYEIHT 521
KQE+ + + G+++++TE+D+++F+ QE + +K+ + R PSVIEFGKYEI T
Sbjct: 673 KQESADVNVIGNKDVVTEEDLDVFKQAQELSWEKIECESGVEDCGRYPSVIEFGKYEIQT 732
Query: 522 WYSSPYPQEYSRLPKLYLCEFCLKYMKSRTILQQHMKKCGWFHPPANEIYRKNNISVFEV 581
WYSSPYPQEY+RLPKLYLCEFCLKYMKS+ IL +H KKCGWFHPPANEIYR+ ++SVFEV
Sbjct: 733 WYSSPYPQEYARLPKLYLCEFCLKYMKSKNILLRHSKKCGWFHPPANEIYRRKDLSVFEV 792
Query: 582 DGNVSTIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVLTQNDVKGCHLVGYFSKEKHCQQK 641
DGN+S IYCQNLCLLAKLFLDHKTLYYDVEPFLFYVLT+ND KGCHLVGYFSKEK CQQK
Sbjct: 793 DGNMSKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVLTKNDEKGCHLVGYFSKEKLCQQK 852
Query: 642 YNVSCIMILPQYQRKGYGRFLIDFSYLLSKREGQAGSPEKPLSDLGRLSYMAYWKSVILE 701
YNVSCIMI+PQ+QR+G+GRFLIDFSYLLS+REGQAGSPEKPLSDLGRLSY+AYWKSVILE
Sbjct: 853 YNVSCIMIMPQHQRQGFGRFLIDFSYLLSRREGQAGSPEKPLSDLGRLSYLAYWKSVILE 912
Query: 702 CLYHQNDKQISIKKLSKLTGICPQDITSTLHHLRMLDFRSDQFVIIRREKLIQDHMAKLQ 761
LYH +++ ISIK +S+ TG+CP DI +TL HL M+D R +FVIIRREKLI HM KL+
Sbjct: 913 YLYHHHERHISIKAISRATGMCPHDIATTLQHLHMIDKRDGRFVIIRREKLILSHMEKLK 972
Query: 762 LNLRPVDVDPECLRWTPVIVSNSVVSEEEEEEAEEGEN--EEPQCQERELEISVGKSVSH 819
R ++DP+ LRWTP+++SN+ VSEEE E +E E E+ C E+E
Sbjct: 973 TCSRANELDPDSLRWTPILISNAAVSEEEREAEKEAERLMEQASCWEKE----------- 1021
Query: 820 ENKEQDSYSVESEKKPEVMAPVSSTRLSKQVLPHDSLPANSQPSRRGRWGRKNRKTQERF 879
EQ+ S + + +P +K + +S P + RG+
Sbjct: 1022 ---EQEILSTRANSR---QSPAKVQSKNKYLHSPESRPVTGE---RGQ------------ 1060
Query: 880 GDKDSKLLLEETSSAPQEQYGECGEKSEATQEQYTESEEQLVASEEQPSQDGKPDLPKRR 939
LLE + + +E+ E E+ E +E+ E EE+ EE+ ++ P R
Sbjct: 1061 -------LLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRL 1113
Query: 940 LSEGVEPWRGQLK-KSPEALKCRLTEGSERLPRRYSEGDRAVLRGFSESSEEEEEP-ESP 997
+P +K K P LK +R +R SE++E EP ++
Sbjct: 1114 ----TKPQSVAIKRKRPFVLK------KKRGRKRRRINSSVTTETISETTEVLNEPFDNS 1163
Query: 998 RSSSPPILTKPTLKRKKPFLHRRRRVRKRKHHNSSVVTETISETTEVLDEPFEDSDSERP 1057
P +PT + + R+ +RK H
Sbjct: 1164 DEERPMPQLEPTCEIEVEEDGRKPVLRKAFQH---------------------------- 1195
Query: 1058 MPRLEPTFEIDEEEEEEDENELFPREYFRRLSSQDVLRCQSSSKRKSKDEEEDEESDDAD 1117
+P + EEEE +N F K+ D + +DD+
Sbjct: 1196 ----QPGKKRQTEEEEGKDNHCF----------------------KNADPCRNNMNDDSS 1229
Query: 1118 DTPILKPVSLLRKRDVKNSPLEPDTSTPLKKKKGWPKGKSRKPIHWKKRPGRKPGFKLSR 1177
+ K K++P PLK K+ WPKG R W++ RK GFKL+
Sbjct: 1230 NL----------KEGSKDNP------EPLKCKQVWPKGTKRGLSKWRQNKERKTGFKLNL 1273
Query: 1178 EIMPVSTQACVIEPIVSIPKAGRKPKIQESEETVEPKEDMPLPEERKEEEEMQAEA-EEA 1236
P + +EP + ++E +ET E K P P +EE + EA
Sbjct: 1274 YTPPETP----MEP-------DEQVTVEEQKETSEGKTS-PSPIRIEEEVKETGEALLPQ 1321
Query: 1237 EEGEEEDAASSEVPAASPADSSNSPETETKEPEVEEEEEKPRVSEEQRQSEEEQ------ 1290
EE E+ + P SP + PE + +PE EEEEE+ EE+ + EE+
Sbjct: 1322 EENRREETCAPVSPNTSPGE---KPEDDLIKPEEEEEEEEEEEEEEEEEEGEEEEGGGNV 1378
Query: 1291 ---------QELEEPE-------------PEEEEDAAAETAQNDDHDADDEDDGHLESTK 1328
QE EEPE EEEE+ E + N+DHDADDEDD H+ES
Sbjct: 1379 EKDPDGAKSQEKEEPEISTEKEDSARLDDHEEEEEEDEEPSHNEDHDADDEDDSHMESA- 1437
Query: 1329 KKELEEQPTREDVKEEPGVQESFLDANMQKSREKIKDKEETELD------SEEEQPSHDT 1382
+ E EE P RE KE QE+FLD N+Q + + +D SE ++ + D
Sbjct: 1438 EVEKEELP-RESFKEVLENQETFLDLNVQPGHSNPEVLMDCGVDLTASCNSEPKELAGDP 1496
Query: 1383 SVV----SEQMAGSEDDHEEDSHTKEELIELKEEEEIPHSELDLETVQAVQSLTQEESSE 1438
V E G + ++ ++KE E KE E+D ETVQAVQSLTQ ESSE
Sbjct: 1497 EAVPESDEEPPPGEQAQKQDQKNSKEVDTEFKEGNPAT-MEIDSETVQAVQSLTQ-ESSE 1554
Query: 1439 HEGAYQDCEETLAACQTLQSYTQADEDPQM-SMVEDCHASEHNSPISSVQSHPSQSVRSV 1497
+ +QDC ET AC++LQ+YT+AD+ PQ+ + ++DC S+H+SP+SSV SHP QSVRSV
Sbjct: 1555 QDDTFQDCAETQEACRSLQNYTRADQSPQIATTLDDCQQSDHSSPVSSVHSHPGQSVRSV 1614
Query: 1498 SSPNVPALESGYTQISPEQGSLSAPSMQNMETSPMMDVPSVSDHSQQVVDSGFSDLGSIE 1557
+SP+VPALE+ Y QISP+Q ++S PS+QNMETSPMMDVPSVSDHSQQVVDSGFSDLGSIE
Sbjct: 1615 NSPSVPALENSYAQISPDQSAISVPSLQNMETSPMMDVPSVSDHSQQVVDSGFSDLGSIE 1674
Query: 1558 STTENYENPSSYDSTMGGSICGNSSSQSSCSYGGLSSSSSLTQSSCVVTQQMASMGSSCS 1617
STTENYENPSSYDSTMGGSICGN SSQ+SCSY L +SSSLTQSSC VTQQM+++ SCS
Sbjct: 1675 STTENYENPSSYDSTMGGSICGNGSSQNSCSYSNL-TSSSLTQSSCAVTQQMSNISGSCS 1733
Query: 1618 MMQQSSVQPAANCSIKSPQSCVVERPPSNQQQQPPPPPPQQPQPPPPQPQPAPQPPPPQQ 1677
M+QQ+S+ CS+KSPQ CVVERPPS+ QQ
Sbjct: 1734 MLQQTSISSPPTCSVKSPQGCVVERPPSSSQQ---------------------------- 1765
Query: 1678 QPQQQPQPQPQQPPPPPPPQQQPPLSQCSMNNSFTPAPMIMEIPESGSTGNISIYERI-P 1736
L+QCSM +FTP + EIPE+ S NI +YER+
Sbjct: 1766 ------------------------LAQCSMAANFTPPMQLAEIPET-SNANIGLYERMGQ 1800
Query: 1737 GDFGAGSYSQPSATFSLAKLQQLTNTIMDPHAMPYSHSPAVTSYATSVS----LSNTGLA 1792
DFGAG Y QPSATFSLAKLQQLTNT++D H++PYSHS AVTSYA S S LSNTGL
Sbjct: 1801 SDFGAGHYPQPSATFSLAKLQQLTNTLID-HSLPYSHSAAVTSYANSASLSTPLSNTGLV 1859
Query: 1793 QLAPS-HPLAGTPQAQATMTPPPNLASTTMNLTSPLLQCNMSATNIGIPHTQRLQGQMPV 1851
QL+ S H + G PQAQATMTPPPNL MNL PLLQ NM+A+NIGI H+QRLQ Q+
Sbjct: 1860 QLSQSPHSVPGGPQAQATMTPPPNLTPPPMNLPPPLLQRNMAASNIGISHSQRLQTQIAS 1919
Query: 1852 KGHISIRSKSAPL-PSAAAHQQQLYGRSPSAVAMQAGPRALAVQRGMNMGVNLMPTPAYN 1910
KGHIS+R+KSA L P+AA HQ Q+YGRS VAMQ R L +QRGMNM VNLMP PAYN
Sbjct: 1920 KGHISMRTKSASLSPAAATHQSQIYGRS-QTVAMQGPARTLTMQRGMNMSVNLMPAPAYN 1978
Query: 1911 VNS--MNMNTLNAMNSYRMTQPMMNSSYHSNPAYMNQTAQYPMQMQMGMMGSQAYTQQPM 1968
VNS MNMNTLNAMN Y M+QPMMNS YHSN YMNQT QYPMQMQMGMMG+Q Y QQPM
Sbjct: 1979 VNSVNMNMNTLNAMNGYSMSQPMMNSGYHSNHGYMNQTPQYPMQMQMGMMGTQPYAQQPM 2038
Query: 1969 QPNPHGNMMYTGPSHHSYMNAAGVPKQSLNGPYMRR 2004
Q PHGNMMYT P HH YMN G+ KQSLNG YMRR
Sbjct: 2039 QTPPHGNMMYTAPGHHGYMN-TGMSKQSLNGSYMRR 2073
Score = 602 bits (1553), Expect = e-172
Identities = 302/476 (63%), Positives = 365/476 (76%), Gaps = 31/476 (6%)
Query: 1 MVKLANPLYTEWILEAIKKVKKQKQRPSEERICNAVSSSHGLDRKTVLEQLELSVKDGTI 60
MVKLANPLYTEWILEAI+K+KKQKQRPSEERIC+AVS+SHGLD+KTV EQLELSV+DG++
Sbjct: 1 MVKLANPLYTEWILEAIQKIKKQKQRPSEERICHAVSTSHGLDKKTVSEQLELSVQDGSV 60
Query: 61 LKVSNKGLNSYKDPDNPGRIALPKPR--------NHGKLDNKQNVDWNKLIKRAVEGLAE 112
LKV+NKGL SYKDPDNPGR + KP + G ++ +NVDWNKL++RA+EGL E
Sbjct: 61 LKVTNKGLASYKDPDNPGRFSSVKPGTFPKSAKGSRGSCNDLRNVDWNKLLRRAIEGLEE 120
Query: 113 SGGSTLKSIERFLKGQKDVSALFGGSAASGFHQQLRLAIKRAIGHGRLLKDGPLYRLNTK 172
GS+LK+IE++L+ Q D+++ A F Q+LRL KRA+ +GRLLKDGP YR+N
Sbjct: 121 PNGSSLKNIEKYLRSQSDLTSTTNNPA---FQQRLRLGAKRAVNNGRLLKDGPQYRVNYG 177
Query: 173 ATNVDGKESCESL--SCLPPVSLLPHEKDKPVAEPIPICSFCLGTKEQNREKKPEELISC 230
+ + G S S LPPVSLLPHEKD+P A+PIPICSFCLGTKE NREKKPEEL+SC
Sbjct: 178 SLDGKGAPQYPSAFPSSLPPVSLLPHEKDQPRADPIPICSFCLGTKESNREKKPEELLSC 237
Query: 231 ADCGNSGHPSCLKFSPELTVRVKALRWQCIECKTCSSCRDQGKNADNMLFCDSCDRGFHM 290
ADCG+SGHPSCLKF PELT VKALRWQCIECKTCS+CR QG+NADNMLFCDSCDRGFHM
Sbjct: 238 ADCGSSGHPSCLKFCPELTTNVKALRWQCIECKTCSACRVQGRNADNMLFCDSCDRGFHM 297
Query: 291 ECCDPPLTRMPKGMWICQICRPRKKGRKLLQKKAAQIKRRYTNPIGRPKNRLKKQ---NT 347
ECCDPPL+RMPKGMWICQ+CRP+KKGRKLL +KAAQIKRRY PIGRPKN+LK++ T
Sbjct: 298 ECCDPPLSRMPKGMWICQVCRPKKKGRKLLHEKAAQIKRRYAKPIGRPKNKLKQRLLSVT 357
Query: 348 VSKGPFSKV--RTGPGRGRKRKITLSSQSASSSSEEGYLERIDGLDFCRD---------- 395
+G + R PGRG+K K+ + S ++S + R+ D R
Sbjct: 358 SDEGSMNAFTGRGSPGRGQKTKVCTTPSSGHAASGKDSSSRLAVTDPTRPGATTKITTTS 417
Query: 396 ---SNVSLKFNKKTKGLIDGLTKFFTPSPDGRKARGEVVDYSEQYRIRKRGNRKSS 448
S +LK NKKTKGLIDGLTKFFTPSPDGR++RGE++D+S+ YR RK+ ++K S
Sbjct: 418 TYISASTLKVNKKTKGLIDGLTKFFTPSPDGRRSRGEIIDFSKHYRPRKKVSQKQS 473
>gi|5901962 MYST histone acetyltransferase 2 [Homo sapiens]
Length = 611
Score = 365 bits (937), Expect = e-100
Identities = 175/309 (56%), Positives = 230/309 (74%), Gaps = 4/309 (1%)
Query: 474 QEIMTEKDMELFRDIQEQA---LQKVGVTGPPDPQVRCPSVIEFGKYEIHTWYSSPYPQE 530
+ + +E D++LFR Q +A L+K+ + G I FG+YE+ TWY SPYP+E
Sbjct: 299 ENLTSEYDLDLFRRAQARASEDLEKLRLQGQITEGSNMIKTIAFGRYELDTWYHSPYPEE 358
Query: 531 YSRLPKLYLCEFCLKYMKSRTILQQHMKKCGWFHPPANEIYRKNNISVFEVDGNVSTIYC 590
Y+RL +LY+CEFCLKYMKS+TIL++HM KC W HPP +EIYRK +ISVFEVDG + IYC
Sbjct: 359 YARLGRLYMCEFCLKYMKSQTILRRHMAKCVWKHPPGDEIYRKGSISVFEVDGKKNKIYC 418
Query: 591 QNLCLLAKLFLDHKTLYYDVEPFLFYVLTQNDVKGCHLVGYFSKEKHCQQKYNVSCIMIL 650
QNLCLLAKLFLDHKTLYYDVEPFLFYV+T+ D GCHL+GYFSKEK+ YNVSCI+ +
Sbjct: 419 QNLCLLAKLFLDHKTLYYDVEPFLFYVMTEADNTGCHLIGYFSKEKNSFLNYNVSCILTM 478
Query: 651 PQYQRKGYGRFLIDFSYLLSKREGQAGSPEKPLSDLGRLSYMAYWKSVILECLYHQNDKQ 710
PQY R+GYG+ LIDFSYLLSK E + GSPE+PLSDLG +SY +YWK V+L L++ K+
Sbjct: 479 PQYMRQGYGKMLIDFSYLLSKVEEKVGSPERPLSDLGLISYRSYWKEVLLRYLHNFQGKE 538
Query: 711 ISIKKLSKLTGICPQDITSTLHHLRMLDFRSDQFVIIRREKLIQDHMAK-LQLNLRPVDV 769
ISIK++S+ T + P DI STL L+ML + + ++++R+ LI + +AK + + +
Sbjct: 539 ISIKEISQETAVNPVDIVSTLQALQMLKYWKGKHLVLKRQDLIDEWIAKEAKRSNSNKTM 598
Query: 770 DPECLRWTP 778
DP CL+WTP
Sbjct: 599 DPSCLKWTP 607
>gi|226371636 MYST histone acetyltransferase 1 isoform 1 [Homo
sapiens]
Length = 458
Score = 315 bits (808), Expect = 2e-85
Identities = 152/274 (55%), Positives = 189/274 (68%), Gaps = 1/274 (0%)
Query: 505 QVRCPSVIEFGKYEIHTWYSSPYPQEYSRLPKLYLCEFCLKYMKSRTILQQHMKKCGWFH 564
+V+ I G YEI WY SP+P++Y + PKL+LCE+CLKYMK + H+ +C W
Sbjct: 175 KVKYVDKIHIGNYEIDAWYFSPFPEDYGKQPKLWLCEYCLKYMKYEKSYRFHLGQCQWRQ 234
Query: 565 PPANEIYRKNNISVFEVDGNVSTIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVLTQNDVK 624
PP EIYRK+NISV+EVDG IYCQNLCLLAKLFLDHKTLY+DVEPF+FY+LT+ D +
Sbjct: 235 PPGKEIYRKSNISVYEVDGKDHKIYCQNLCLLAKLFLDHKTLYFDVEPFVFYILTEVDRQ 294
Query: 625 GCHLVGYFSKEKHCQQKYNVSCIMILPQYQRKGYGRFLIDFSYLLSKREGQAGSPEKPLS 684
G H+VGYFSKEK NV+CI+ LP YQR+GYG+FLI FSY LSK E GSPEKPLS
Sbjct: 295 GAHIVGYFSKEKESPDGNNVACILTLPPYQRRGYGKFLIAFSYELSKLESTVGSPEKPLS 354
Query: 685 DLGRLSYMAYWKSVILECLYHQNDKQISIKKLSKLTGICPQDITSTLHHLRMLDFRSDQF 744
DLG+LSY +YW V+LE L +SIK LS++T I DI STL L M+ + Q
Sbjct: 355 DLGKLSYRSYWSWVLLEIL-RDFRGTLSIKDLSQMTSITQNDIISTLQSLNMVKYWKGQH 413
Query: 745 VIIRREKLIQDHMAKLQLNLRPVDVDPECLRWTP 778
VI KL+++H+ Q P+ VD CL+W P
Sbjct: 414 VICVTPKLVEEHLKSAQYKKPPITVDSVCLKWAP 447
>gi|36287069 K(lysine) acetyltransferase 5 isoform 1 [Homo sapiens]
Length = 546
Score = 303 bits (777), Expect = 9e-82
Identities = 147/273 (53%), Positives = 191/273 (69%), Gaps = 9/273 (3%)
Query: 512 IEFGKYEIHTWYSSPYPQEYSRLPKLYLCEFCLKYMKSRTILQQHMKKCGWFHPPANEIY 571
IE G++ + WY SPYPQE + LP LYLCEFCLKY +S LQ+H+ KC HPP NEIY
Sbjct: 268 IELGRHRLKPWYFSPYPQELTTLPVLYLCEFCLKYGRSLKCLQRHLTKCDLRHPPGNEIY 327
Query: 572 RKNNISVFEVDGNVSTIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVLTQNDVKGCHLVGY 631
RK IS FE+DG + Y QNLCLLAK FLDHKTLYYD +PFLFYV+T+ D KG H+VGY
Sbjct: 328 RKGTISFFEIDGRKNKSYSQNLCLLAKCFLDHKTLYYDTDPFLFYVMTEYDCKGFHIVGY 387
Query: 632 FSKEKHCQQKYNVSCIMILPQYQRKGYGRFLIDFSYLLSKREGQAGSPEKPLSDLGRLSY 691
FSKEK + YNV+CI+ LP YQR+GYG+ LI+FSY LSK EG+ G+PEKPLSDLG LSY
Sbjct: 388 FSKEKESTEDYNVACILTLPPYQRRGYGKLLIEFSYELSKVEGKTGTPEKPLSDLGLLSY 447
Query: 692 MAYWKSVILECLYHQNDK-----QISIKKLSKLTGICPQDITSTLHHLRMLDFRSDQFVI 746
+YW ILE L + QI+I ++S++T I +D+ STL +L ++++ Q+++
Sbjct: 448 RSYWSQTILEILMGLKSESGERPQITINEISEITSIKKEDVISTLQYLNLINYYKGQYIL 507
Query: 747 IRREKLIQDH-MAKLQLNLRPVDVDPECLRWTP 778
E ++ H A L+ LR +D +CL +TP
Sbjct: 508 TLSEDIVDGHERAMLKRLLR---IDSKCLHFTP 537
>gi|36287060 K(lysine) acetyltransferase 5 isoform 3 [Homo sapiens]
Length = 461
Score = 303 bits (777), Expect = 9e-82
Identities = 147/273 (53%), Positives = 191/273 (69%), Gaps = 9/273 (3%)
Query: 512 IEFGKYEIHTWYSSPYPQEYSRLPKLYLCEFCLKYMKSRTILQQHMKKCGWFHPPANEIY 571
IE G++ + WY SPYPQE + LP LYLCEFCLKY +S LQ+H+ KC HPP NEIY
Sbjct: 183 IELGRHRLKPWYFSPYPQELTTLPVLYLCEFCLKYGRSLKCLQRHLTKCDLRHPPGNEIY 242
Query: 572 RKNNISVFEVDGNVSTIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVLTQNDVKGCHLVGY 631
RK IS FE+DG + Y QNLCLLAK FLDHKTLYYD +PFLFYV+T+ D KG H+VGY
Sbjct: 243 RKGTISFFEIDGRKNKSYSQNLCLLAKCFLDHKTLYYDTDPFLFYVMTEYDCKGFHIVGY 302
Query: 632 FSKEKHCQQKYNVSCIMILPQYQRKGYGRFLIDFSYLLSKREGQAGSPEKPLSDLGRLSY 691
FSKEK + YNV+CI+ LP YQR+GYG+ LI+FSY LSK EG+ G+PEKPLSDLG LSY
Sbjct: 303 FSKEKESTEDYNVACILTLPPYQRRGYGKLLIEFSYELSKVEGKTGTPEKPLSDLGLLSY 362
Query: 692 MAYWKSVILECLYHQNDK-----QISIKKLSKLTGICPQDITSTLHHLRMLDFRSDQFVI 746
+YW ILE L + QI+I ++S++T I +D+ STL +L ++++ Q+++
Sbjct: 363 RSYWSQTILEILMGLKSESGERPQITINEISEITSIKKEDVISTLQYLNLINYYKGQYIL 422
Query: 747 IRREKLIQDH-MAKLQLNLRPVDVDPECLRWTP 778
E ++ H A L+ LR +D +CL +TP
Sbjct: 423 TLSEDIVDGHERAMLKRLLR---IDSKCLHFTP 452
>gi|36287049 K(lysine) acetyltransferase 5 isoform 2 [Homo sapiens]
Length = 513
Score = 303 bits (777), Expect = 9e-82
Identities = 147/273 (53%), Positives = 191/273 (69%), Gaps = 9/273 (3%)
Query: 512 IEFGKYEIHTWYSSPYPQEYSRLPKLYLCEFCLKYMKSRTILQQHMKKCGWFHPPANEIY 571
IE G++ + WY SPYPQE + LP LYLCEFCLKY +S LQ+H+ KC HPP NEIY
Sbjct: 235 IELGRHRLKPWYFSPYPQELTTLPVLYLCEFCLKYGRSLKCLQRHLTKCDLRHPPGNEIY 294
Query: 572 RKNNISVFEVDGNVSTIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVLTQNDVKGCHLVGY 631
RK IS FE+DG + Y QNLCLLAK FLDHKTLYYD +PFLFYV+T+ D KG H+VGY
Sbjct: 295 RKGTISFFEIDGRKNKSYSQNLCLLAKCFLDHKTLYYDTDPFLFYVMTEYDCKGFHIVGY 354
Query: 632 FSKEKHCQQKYNVSCIMILPQYQRKGYGRFLIDFSYLLSKREGQAGSPEKPLSDLGRLSY 691
FSKEK + YNV+CI+ LP YQR+GYG+ LI+FSY LSK EG+ G+PEKPLSDLG LSY
Sbjct: 355 FSKEKESTEDYNVACILTLPPYQRRGYGKLLIEFSYELSKVEGKTGTPEKPLSDLGLLSY 414
Query: 692 MAYWKSVILECLYHQNDK-----QISIKKLSKLTGICPQDITSTLHHLRMLDFRSDQFVI 746
+YW ILE L + QI+I ++S++T I +D+ STL +L ++++ Q+++
Sbjct: 415 RSYWSQTILEILMGLKSESGERPQITINEISEITSIKKEDVISTLQYLNLINYYKGQYIL 474
Query: 747 IRREKLIQDH-MAKLQLNLRPVDVDPECLRWTP 778
E ++ H A L+ LR +D +CL +TP
Sbjct: 475 TLSEDIVDGHERAMLKRLLR---IDSKCLHFTP 504
>gi|226371638 MYST histone acetyltransferase 1 isoform 2 [Homo
sapiens]
Length = 467
Score = 300 bits (769), Expect = 7e-81
Identities = 146/263 (55%), Positives = 182/263 (69%), Gaps = 1/263 (0%)
Query: 505 QVRCPSVIEFGKYEIHTWYSSPYPQEYSRLPKLYLCEFCLKYMKSRTILQQHMKKCGWFH 564
+V+ I G YEI WY SP+P++Y + PKL+LCE+CLKYMK + H+ +C W
Sbjct: 175 KVKYVDKIHIGNYEIDAWYFSPFPEDYGKQPKLWLCEYCLKYMKYEKSYRFHLGQCQWRQ 234
Query: 565 PPANEIYRKNNISVFEVDGNVSTIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVLTQNDVK 624
PP EIYRK+NISV+EVDG IYCQNLCLLAKLFLDHKTLY+DVEPF+FY+LT+ D +
Sbjct: 235 PPGKEIYRKSNISVYEVDGKDHKIYCQNLCLLAKLFLDHKTLYFDVEPFVFYILTEVDRQ 294
Query: 625 GCHLVGYFSKEKHCQQKYNVSCIMILPQYQRKGYGRFLIDFSYLLSKREGQAGSPEKPLS 684
G H+VGYFSKEK NV+CI+ LP YQR+GYG+FLI FSY LSK E GSPEKPLS
Sbjct: 295 GAHIVGYFSKEKESPDGNNVACILTLPPYQRRGYGKFLIAFSYELSKLESTVGSPEKPLS 354
Query: 685 DLGRLSYMAYWKSVILECLYHQNDKQISIKKLSKLTGICPQDITSTLHHLRMLDFRSDQF 744
DLG+LSY +YW V+LE L +SIK LS++T I DI STL L M+ + Q
Sbjct: 355 DLGKLSYRSYWSWVLLEIL-RDFRGTLSIKDLSQMTSITQNDIISTLQSLNMVKYWKGQH 413
Query: 745 VIIRREKLIQDHMAKLQLNLRPV 767
VI KL+++H+ Q P+
Sbjct: 414 VICVTPKLVEEHLKSAQYKKPPI 436
>gi|205830434 D4, zinc and double PHD fingers family 1 isoform c
[Homo sapiens]
Length = 332
Score = 137 bits (345), Expect = 1e-31
Identities = 68/151 (45%), Positives = 88/151 (58%), Gaps = 10/151 (6%)
Query: 179 KESCESLSCLPPVSLLPHEKDKPVAEPIP--ICSFCLGTKEQNREKKPEELISCADCGNS 236
K+ + L+ +P K P IP C FCLG ++ PE+LISCADCG S
Sbjct: 187 KQFYKELAWVPEAQRKHTAKKAPDGTVIPNGYCDFCLGGSKKTG--CPEDLISCADCGRS 244
Query: 237 GHPSCLKFSPELTVRVKALRWQCIECKTCSSCRDQGKNADNMLFCDSCDRGFHMECCDPP 296
GHPSCL+F+ +T V+ RWQCIECK+CS C +N D +LFCD CDRG+HM C PP
Sbjct: 245 GHPSCLQFTVNMTAAVRTYRWQCIECKSCSLC-GTSENDDQLLFCDDCDRGYHMYCLSPP 303
Query: 297 LTRMPKGMWICQICRPRKKGRKLLQKKAAQI 327
+ P+G W C +C R L +K +A I
Sbjct: 304 MAEPPEGSWSCHLCL-----RHLKEKASAYI 329
>gi|205830430 D4, zinc and double PHD fingers family 1 isoform a
[Homo sapiens]
Length = 414
Score = 137 bits (345), Expect = 1e-31
Identities = 68/151 (45%), Positives = 88/151 (58%), Gaps = 10/151 (6%)
Query: 179 KESCESLSCLPPVSLLPHEKDKPVAEPIP--ICSFCLGTKEQNREKKPEELISCADCGNS 236
K+ + L+ +P K P IP C FCLG ++ PE+LISCADCG S
Sbjct: 269 KQFYKELAWVPEAQRKHTAKKAPDGTVIPNGYCDFCLGGSKKTG--CPEDLISCADCGRS 326
Query: 237 GHPSCLKFSPELTVRVKALRWQCIECKTCSSCRDQGKNADNMLFCDSCDRGFHMECCDPP 296
GHPSCL+F+ +T V+ RWQCIECK+CS C +N D +LFCD CDRG+HM C PP
Sbjct: 327 GHPSCLQFTVNMTAAVRTYRWQCIECKSCSLC-GTSENDDQLLFCDDCDRGYHMYCLSPP 385
Query: 297 LTRMPKGMWICQICRPRKKGRKLLQKKAAQI 327
+ P+G W C +C R L +K +A I
Sbjct: 386 MAEPPEGSWSCHLCL-----RHLKEKASAYI 411
>gi|5454004 D4, zinc and double PHD fingers family 2 [Homo sapiens]
Length = 391
Score = 136 bits (342), Expect = 2e-31
Identities = 57/110 (51%), Positives = 75/110 (68%), Gaps = 2/110 (1%)
Query: 202 VAEPIPICSFCLGTKEQNREK-KPEELISCADCGNSGHPSCLKFSPELTVRVKALRWQCI 260
+A P C FCLG + N++ +PEEL+SC+DCG SGHPSCL+F+P + VK RWQCI
Sbjct: 266 LALPNNYCDFCLGDSKINKKTGQPEELVSCSDCGRSGHPSCLQFTPVMMAAVKTYRWQCI 325
Query: 261 ECKTCSSCRDQGKNADNMLFCDSCDRGFHMECCDPPLTRMPKGMWICQIC 310
ECK C+ C +N D +LFCD CDRG+HM C P ++ P+G W C +C
Sbjct: 326 ECKCCNIC-GTSENDDQLLFCDDCDRGYHMYCLTPSMSEPPEGSWSCHLC 374
>gi|205830432 D4, zinc and double PHD fingers family 1 isoform b
[Homo sapiens]
Length = 380
Score = 130 bits (327), Expect = 1e-29
Identities = 66/156 (42%), Positives = 85/156 (54%), Gaps = 18/156 (11%)
Query: 183 ESLSCLPPVSLLPHEKDKPVAEPIP--ICSFCLGTKEQNREKKPEELISCADCGNSGHPS 240
+ L+ +P K P IP C FCLG ++ PE+LISCADCG SGHPS
Sbjct: 229 KELAWVPEAQRKHTAKKAPDGTVIPNGYCDFCLGGSKKTG--CPEDLISCADCGRSGHPS 286
Query: 241 CLKFSPELTVRVKALRWQCIECKTCSSCRDQGKNA---------DNMLFCDSCDRGFHME 291
CL+F+ +T V+ RWQCIECK+CS C + D +LFCD CDRG+HM
Sbjct: 287 CLQFTVNMTAAVRTYRWQCIECKSCSLCGTSENDGASWAGLTPQDQLLFCDDCDRGYHMY 346
Query: 292 CCDPPLTRMPKGMWICQICRPRKKGRKLLQKKAAQI 327
C PP+ P+G W C +C R L +K +A I
Sbjct: 347 CLSPPMAEPPEGSWSCHLCL-----RHLKEKASAYI 377
>gi|194328736 PHD finger protein 10 isoform b [Homo sapiens]
Length = 496
Score = 122 bits (307), Expect = 3e-27
Identities = 59/124 (47%), Positives = 72/124 (58%), Gaps = 8/124 (6%)
Query: 200 KPVAEPIPICSFCLGTKEQNREKKPEELISCADCGNSGHPSCLKFSPELTVRVKALRWQC 259
KP P IC CL KE N++ K E LI C+ C NSGHPSCL + EL +K WQC
Sbjct: 369 KPKVIPNAICGICLKGKESNKKGKAESLIHCSQCENSGHPSCLDMTMELVSMIKTYPWQC 428
Query: 260 IECKTCSSCRDQGKNADNMLFCDSCDRGFHMECCDPPLTRMPKGMWICQICR-----PRK 314
+ECKTC C Q + + M+FCD CDRG+H C L +P G WIC C+ PRK
Sbjct: 429 MECKTCIIC-GQPHHEEEMMFCDMCDRGYHTFCVG--LGAIPSGRWICDCCQRAPPTPRK 485
Query: 315 KGRK 318
GR+
Sbjct: 486 VGRR 489
>gi|194328734 PHD finger protein 10 isoform a [Homo sapiens]
Length = 498
Score = 122 bits (307), Expect = 3e-27
Identities = 59/124 (47%), Positives = 72/124 (58%), Gaps = 8/124 (6%)
Query: 200 KPVAEPIPICSFCLGTKEQNREKKPEELISCADCGNSGHPSCLKFSPELTVRVKALRWQC 259
KP P IC CL KE N++ K E LI C+ C NSGHPSCL + EL +K WQC
Sbjct: 371 KPKVIPNAICGICLKGKESNKKGKAESLIHCSQCENSGHPSCLDMTMELVSMIKTYPWQC 430
Query: 260 IECKTCSSCRDQGKNADNMLFCDSCDRGFHMECCDPPLTRMPKGMWICQICR-----PRK 314
+ECKTC C Q + + M+FCD CDRG+H C L +P G WIC C+ PRK
Sbjct: 431 MECKTCIIC-GQPHHEEEMMFCDMCDRGYHTFCVG--LGAIPSGRWICDCCQRAPPTPRK 487
Query: 315 KGRK 318
GR+
Sbjct: 488 VGRR 491
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 91.3 bits (225), Expect = 9e-18
Identities = 138/700 (19%), Positives = 288/700 (41%), Gaps = 62/700 (8%)
Query: 752 LIQDHMAKLQLNLRPVDVDPECLRWTPVIVSNSVVSEE---EEEEAEEGEN------EEP 802
L + +++QLN++ + E ++ V + + EE +EEE E E E+
Sbjct: 236 LAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKM 295
Query: 803 QCQERELEISVGKSVSHENKEQDSYSVESEKKPEVMAPVSSTRLSKQVLPHDSLPANSQP 862
QE L GK E K E++ E+ R K++ + Q
Sbjct: 296 WRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEE-QMQEQE 354
Query: 863 SRRGRWGRKNRKTQERFGDKDSKLLLEETSSAPQEQYGECGEKSEATQEQYTESEEQLVA 922
+ K R+ +E+ ++ +L +E QEQ E+ Q++ +E+ +
Sbjct: 355 EKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMR 414
Query: 923 SEEQPSQDGKPDLPKRRLSEGVEPWRGQLKKSPEALKCRLTEGSERLPRRYSEGDRAVLR 982
+E+ + + ++++ E + R Q +K E + R E R ++
Sbjct: 415 EQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQ 474
Query: 983 GFSESSEEEEEPESPRSSSPPILTKPTLKRKKPFLHRRRRVRKRKHHNSSVVTETISETT 1042
E+ E+EE E + P +K L + ++++++ E I E
Sbjct: 475 KQEENMWEQEEKEWQQQRLP---------EQKEKLWEQEKMQEQE--------EKIWEQE 517
Query: 1043 EVLDEPFEDSDSERPMPRLEPTFEIDEEEEEEDENELFPREYFRRLSSQD--VLRCQSSS 1100
E + + E E+ M R E ++ E+E++ E E R+ +++ Q+ + +
Sbjct: 518 EKIRDQEEMWGQEKKMWRQE---KMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQ 574
Query: 1101 KRKSKDEEE---DEESDDADDTPILKPVSLLRKRDVKNSPLEPDTSTPLKKKKGWPKGKS 1157
++K+ D+EE +EE + + + ++R+++ K E + +++K W + +
Sbjct: 575 EKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQ--EQEEKMQEQEEKMWEQEEK 632
Query: 1158 RKPIHWKKRPGRKPGFKLSREIMPVSTQACVIEPIVSIPKAGRKPKIQESEETVEPKEDM 1217
+ K + ++ ++ E + K + K+QE EE + +E M
Sbjct: 633 MQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKM 692
Query: 1218 PLPEERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSNSPETETKEPEVEEEEEKP 1277
E+K +E+ + ++ + EEE E + +E + E+EEK
Sbjct: 693 ----EKKTQEQEKKTWDQEKMREEESMRERE------------KKMREEEEMMREQEEKM 736
Query: 1278 RVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQPT 1337
+ EE+ Q +EE+ +E + E+E+ E + + + ++ +K +E+
Sbjct: 737 QEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKM 796
Query: 1338 REDVKEEPGVQESFLDANMQKSREKIKDKEETELDSEEEQPSHDTSV--VSEQMAGSEDD 1395
R+ ++ G +E M+ EK++ +EE EE+ + + E+M G E+
Sbjct: 797 RDQEEKMRGQEE-----KMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEK 851
Query: 1396 HEEDSHTKEELIELKEEEEIPHSELDLETVQAVQSLTQEE 1435
EE +EE +++E+EE + + Q + QEE
Sbjct: 852 MEEKMQGQEE--KMREQEEKMRGQEEKMREQEEKMRGQEE 889
Score = 82.4 bits (202), Expect = 4e-15
Identities = 142/704 (20%), Positives = 291/704 (41%), Gaps = 70/704 (9%)
Query: 772 ECLRWTPV-IVSNSVVSEEEEEEAEEGENEEPQCQERELEISVGKSVSHENKEQDSYSVE 830
+ R +P+ VS S++ E ++ A + E + +S +VS +K+ D Y E
Sbjct: 145 QAFRGSPLGCVSTSLIPGESKDLAGRLHHSWHFAGELQRALS---AVSTRHKKADRYIEE 201
Query: 831 SEKKPEVMAPVSSTRLSKQVLPHDSLPANSQPSRRGRWGRKNRKTQERFGDKDSKLLLEE 890
K+ + + S L + + ++ L + + ++ K++ + K+ K LE
Sbjct: 202 LTKERDAL----SLELYRNTITNEELKKKNAELQEKLPLAESEKSEIQLNVKELKRKLER 257
Query: 891 TSSA-PQEQYGECGEKSEATQEQYTESEEQLVASEEQPSQDGKPDLPKRRLSEGVEPWRG 949
PQ Q E+ +E+ E E+++ EE+ + + RL E R
Sbjct: 258 AKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQ------EERLREQEGKMRE 311
Query: 950 QLKKSPEALKCRLTEGSERLPRRYSEGDRAVLRGFSESSEEEEEPESPRSSSPPILTKPT 1009
Q +K K RL E + L + E LR E E+EE+ +
Sbjct: 312 QEEKMWRQEK-RLREQEKELREQEKE-----LREQKELREQEEQMQ-------------- 351
Query: 1010 LKRKKPFLHRRRRVRKRKHHNSSVVTETISETTEVLDEPFEDSDSERPMPRLEPTFEIDE 1069
++++ + ++R+++ + ++ ++ + D E M +E DE
Sbjct: 352 -EQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERM------WEQDE 404
Query: 1070 EEEEEDENELFPREYFRRLSSQDVLRCQSSSKRKSKDEEE---DEESDDADDTPILKPVS 1126
E++E + + ++ + ++K++D+EE +EE + + +
Sbjct: 405 RLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEE 464
Query: 1127 LLRKRDVKNSPLEPDTSTPLKKKKGWPKGKSRKPIHWKKRPGRKPGFKLSREIMPVSTQA 1186
+R+++ K E + +K+ + +K W++ ++ K+ + + Q
Sbjct: 465 TMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQE 524
Query: 1187 CVIEPIVSIPKAGRKPKIQESEETVEPKEDMPLPEERK---EEEEMQAEAEEAEEG---- 1239
E K R+ K++E E+ + +E+ +E+K +EE M+ + +E E+
Sbjct: 525 ---EMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQ 581
Query: 1240 -----EEEDAASSEVPAASPADSSNSPETETKEPE--VEEEEEKPRVSEEQRQSEEEQQ- 1291
EEE E + E + +E E ++E+EEK EE+ Q +EE+
Sbjct: 582 EEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMW 641
Query: 1292 ELEEPEPEEEEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQPTREDVKEEPGVQESF 1351
E EE E+EE + + + E + E K +E EE+ ++ E+ ++
Sbjct: 642 EQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEK 701
Query: 1352 LDANMQKSREKIKDKE-ETELDSEEEQPSHDTSVVSEQMAGSEDDHEEDSHTKEELIE-- 1408
+ +K RE+ +E E ++ EEE + EQ ++ EE +E++ E
Sbjct: 702 KTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQE 761
Query: 1409 --LKEEEEIPHSELDLETVQAVQSLTQEESSEHEGAYQDCEETL 1450
+ E++ +P + L + +Q QE+ E E +D EE +
Sbjct: 762 EKMWEQQRLPEQKEKLWEHEKMQE--QEKIWEQEEKMRDQEEKM 803
Score = 80.5 bits (197), Expect = 2e-14
Identities = 124/669 (18%), Positives = 262/669 (39%), Gaps = 85/669 (12%)
Query: 783 NSVVSEEEEEEAEEGENEEPQCQERELEISVGKSVSHENKEQDSYSVESEKKPEVMAPVS 842
N++ +EE +++ E + + P + + EI + E+ + + P+V
Sbjct: 216 NTITNEELKKKNAELQEKLPLAESEKSEIQLNVKELKRKLERAKFLL-----PQVQTNTL 270
Query: 843 STRLSKQV--LPHDSLPANSQPSRRGRWGRKNRKTQERFGDKDSKLLLEETSSAPQEQYG 900
+ +Q L Q + R + R+ + + +++ K+ +E QE+
Sbjct: 271 QEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKEL 330
Query: 901 ECGEKSEATQEQYTESEEQLVASEEQP--------SQDGKPDLPKRRLSEGVEPWRGQLK 952
EK Q++ E EEQ+ EE+ Q+ K + RL E + R Q +
Sbjct: 331 REQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQ 390
Query: 953 KSPEALKCRLTEGSERLPRRYSEGDRAVLRGFSESSEEEEEPESPRSSSPPILTKPTLKR 1012
K + + R+ E ERL R E R + + + + EE + + ++
Sbjct: 391 KMRDQEE-RMWEQDERL-REKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQE 448
Query: 1013 KKPFLHRRRRVRKRKHHNSSVVTETISETTEVLDEPFEDSDSERPMPRLEPTFEIDEEEE 1072
++ R +++R+ + ET+ E E + + E+ + E+EE
Sbjct: 449 EERIREREKKMREEE--------ETMREQEEKMQKQEEN---------------MWEQEE 485
Query: 1073 EEDENELFPREYFRRLSSQDVLRCQSSSKRKSKDEEEDEESDDADDTPILKPVSLLRKRD 1132
+E + + P E +L Q+ ++ Q + +++ D+E + + + + R+
Sbjct: 486 KEWQQQRLP-EQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKM---RE 541
Query: 1133 VKNSPLEPDTSTPLKKKKGWPKGKSRKPIHWKKRPGRKPGFKLSREIMPVSTQACVIEPI 1192
++ E + +++K W + E M TQ
Sbjct: 542 QEDQMWEQEEKMRDQEQKMWDQ----------------------EERMEKKTQE------ 573
Query: 1193 VSIPKAGRKPKIQESEETVEPKEDMPLPEER-KEEEEMQAEAEEAEEGEEEDAASSEVPA 1251
++ K + EE + +E M E++ +EEEEM E EE + +EE E
Sbjct: 574 -------QEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKM 626
Query: 1252 ASPADSSNSPETETKEPEVEEEEEKPRVSEEQRQSEE-----EQQELEEPEPEEEEDAAA 1306
+ E + E E + E++ ++ E+QR E+ E ++++E E +E++
Sbjct: 627 WEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKI 686
Query: 1307 ETAQNDDHDADDEDDGHLESTKKKELEEQPTREDVKEEPGVQESFLDANMQKSREKIKDK 1366
+ + +++ + K +E E RE E + MQ+ EK++++
Sbjct: 687 WEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQ 746
Query: 1367 EETELDSEEEQPSHDTSVVSEQMAGSEDDHEEDSHTKEELIELKEEEEIPHSELDLETVQ 1426
EE + EE+ + + +Q + + + +E ++ E+EE + + Q
Sbjct: 747 EEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQ 806
Query: 1427 AVQSLTQEE 1435
+ QEE
Sbjct: 807 EEKMRGQEE 815
Score = 59.3 bits (142), Expect = 4e-08
Identities = 56/239 (23%), Positives = 100/239 (41%), Gaps = 12/239 (5%)
Query: 1221 EERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSNSPETETKEPEVE--EEEEKPR 1278
EE +E+E+ + EE +EE E + E +E E E E+E++ R
Sbjct: 279 EELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELR 338
Query: 1279 VSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQPTR 1338
+E R+ EE+ QE EE E+EE + + + L +K+ E++
Sbjct: 339 EQKELREQEEQMQEQEEKMWEQEEK------MREQEEKMWRQEERLWEQEKQMREQEQKM 392
Query: 1339 EDVKEEPGVQESFLDANMQKSREKIKDKEETELDSEEEQPSHDTSVVSEQMAGSEDDHEE 1398
D +E Q+ L ++ RE+ K E+ E EE++ +Q E+ +E
Sbjct: 393 RDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQ----EEKMQE 448
Query: 1399 DSHTKEELIELKEEEEIPHSELDLETVQAVQSLTQEESSEHEGAYQDCEETLAACQTLQ 1457
+ +E +++EEEE + + Q QEE + + +E L + +Q
Sbjct: 449 EERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQ 507
Score = 52.0 bits (123), Expect = 6e-06
Identities = 96/505 (19%), Positives = 198/505 (39%), Gaps = 59/505 (11%)
Query: 788 EEEEEEAEEGENEEPQCQERELEISVGKSVSHENKEQDSYSVESEKKPEVMAPVSSTRLS 847
E++ + EE EE + +ERE ++ + E +E+ +K+ E M
Sbjct: 436 EKKTRDQEEKMQEEERIREREKKMREEEETMREQEEK------MQKQEENMWEQEEKEWQ 489
Query: 848 KQVLPHDSLPANSQPSRRGR----WGRKNR-KTQERFGDKDSKLLLEETSSAPQEQYGEC 902
+Q LP Q + + W ++ + + QE ++ K+ +E ++Q E
Sbjct: 490 QQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQ 549
Query: 903 GEKSEATQEQYTESEEQLVASEEQPSQDGKPDLPKRRLSEGVEPWRGQLKKSPEALKCRL 962
EK +++ + EE++ ++ + K R E + ++++ E ++
Sbjct: 550 EEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMR--- 606
Query: 963 TEGSERLPRRYSEGDRAVLRGFSESSEEEEEPESPRSSSPPILTKPTLKRKKPFLHRRRR 1022
E E++ E + + + E+EE+ + K + +K + +R
Sbjct: 607 -EQEEKM----QEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLP 661
Query: 1023 VRKRK--HHNSSVVTETISETTEVLDEPFEDSDSERPMPRLEPTFEIDEEEEEED--ENE 1078
+K K H E + E E + E ++ ++ + + T++ ++ EEE E E
Sbjct: 662 EQKEKLWEHEKMQEQEKMQEQEEKIWE--QEKMEKKTQEQEKKTWDQEKMREEESMRERE 719
Query: 1079 LFPREYFRRLSSQDVLRCQSSSKRKSKDEEEDEESDDADDTPILKPVSLLRKRDVKNSPL 1138
RE + Q+ + Q ++ + EEE E ++ K R + K
Sbjct: 720 KKMREEEEMMREQEE-KMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLW 778
Query: 1139 EPDTSTPLKKKKGWPKGKSRKPIHWKKRPGRKPGFKLSREIMPVSTQACVIEPIVSIPKA 1198
E + +++K W + + + K R G++ + E M +
Sbjct: 779 EHEKMQ--EQEKIWEQEEKMRDQEEKMR-GQEEKMRGQEEKMRGQEEKMW---------- 825
Query: 1199 GRKPKIQESEETVEPKEDMPLPEERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPADSS 1258
G++ K+ EE + +E+ +E K EE+MQ + E+ E EE
Sbjct: 826 GQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEE----------------- 868
Query: 1259 NSPETETKEPEVEEEEEKPRVSEEQ 1283
+ +E ++ E+EEK R EE+
Sbjct: 869 ---KMRGQEEKMREQEEKMRGQEEK 890
Score = 35.4 bits (80), Expect = 0.57
Identities = 34/155 (21%), Positives = 62/155 (40%), Gaps = 9/155 (5%)
Query: 788 EEE--EEEAEEGENEEPQCQERELEISVGKSVSHENKEQDSYSVESEKKPEVMAPVSSTR 845
EEE E+E + E EE +++ L K HE ++ E E+K +
Sbjct: 747 EEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQ 806
Query: 846 LSKQVLPHDSLPANSQP---SRRGRWGRKNRK--TQERFGDKDSKLLLEETSSAPQEQYG 900
K + + + WG++ + +E+ ++ K+ EE +E+
Sbjct: 807 EEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKM--EEKMQGQEEKMR 864
Query: 901 ECGEKSEATQEQYTESEEQLVASEEQPSQDGKPDL 935
E EK +E+ E EE++ EE+ G P +
Sbjct: 865 EQEEKMRGQEEKMREQEEKMRGQEEKIYCVGSPPI 899
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 90.1 bits (222), Expect = 2e-17
Identities = 119/577 (20%), Positives = 239/577 (41%), Gaps = 40/577 (6%)
Query: 882 KDSKLLLEETSSAPQEQYGECGEKSEATQEQYTESEEQLVASEEQPSQDGKPDLPKRRLS 941
+++++ E T +E E G++ E +E+ E E+ ++ P+++ P++
Sbjct: 462 EETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEE--ETKSPPAEEAAS--PEK--- 514
Query: 942 EGVEPWRGQLKKSPEALKCRLTEGSERLPRRYSEGDRAVLRGFSESSEEEEEPESPRSSS 1001
E P + + K EA E + E ++ + ++S E + PE + S
Sbjct: 515 EAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKS 574
Query: 1002 PPILTKPTLKRKKPFLHRRRRVRKRK--HHNSSVVTETISETTEVLDEPFEDSDSERPMP 1059
P + P K K P + + K S V E E E++ S +
Sbjct: 575 PAEVKSPE-KAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVK 633
Query: 1060 RLEPTFEIDEEEEEEDENELFPREYFRRL--SSQDVLRCQSSSKRKSKDEEEDE-ESDDA 1116
E +EE + E P + + ++ ++ ++ S K+K + E +S +
Sbjct: 634 SPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEK 693
Query: 1117 DDTPILKPVSLLRKRDVKNSPLEPDTSTPLKKKKGWPKGKSRKPIHWKKRPGRKPGFKLS 1176
+P+ + + + SP++ + +P K K P + K K P ++
Sbjct: 694 AKSPVKEEA---KSPEKAKSPVKEEAKSPEKAKS--PVKEEAKTPEKAKSPVKEEAKSPE 748
Query: 1177 REIMPVSTQAC-VIEPIVSIP--KAGRKPKIQESEETVEP-KEDMPLPEERKEEEEMQAE 1232
+ P + V P P + R P + E+ P KE++ PE+ K + A+
Sbjct: 749 KAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAK 808
Query: 1233 AEEAEEGEEEDAASSEVPAASPADSSNSP-ETETKEPEVEEEEEK----PRVSEEQRQSE 1287
A E E ++E+ SP P E + KEP + EEEK P+ E++ +
Sbjct: 809 APEKEIPKKEE-------VKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKK 861
Query: 1288 EEQQELEEPEP--EEEEDAAAETAQNDDHDA---DDEDDGHLESTKKKELEEQPTREDVK 1342
EE + E P+P EE+++ A E + +A + ED + + +K+ + +ED K
Sbjct: 862 EEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAK 921
Query: 1343 EEPGVQESFLDANMQKSREKIKDKEETELDSEEEQPSHDTSVVSEQMAGSEDDHEEDSHT 1402
+ + + + + K++E K E+ E E++ + + E+ +E +ED T
Sbjct: 922 PKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKT 981
Query: 1403 -KEELIELKEEEEIPHSELDLETVQAVQSLTQEESSE 1438
+E + K E+ S D + + + T++++++
Sbjct: 982 LSKEPSKPKAEKAEKSSSTDQKDSKPPEKATEDKAAK 1018
Score = 86.3 bits (212), Expect = 3e-16
Identities = 140/648 (21%), Positives = 252/648 (38%), Gaps = 107/648 (16%)
Query: 784 SVVSEEEEEEAEEGENEEPQCQERELEISVGKSVSHENKEQDSYSVESEKKPEVMAPVSS 843
+V+ EE+ EE + E E + +E+E + GK +E+ E K P S
Sbjct: 454 TVIVEEQTEETQVTE-EVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASP 512
Query: 844 TRLSKQVLPHDSLPANSQPSRRGRWGRKNRKTQERFGDKDSKLLLEETSSAPQEQYGECG 903
+ +K + + A S + + + E + +K +E + +P E
Sbjct: 513 EKEAKSPVKEE---AKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEK 569
Query: 904 EKSEATQEQYTESEEQLVASEE--QPSQDGKPDLPKRRLSEGVEPWRGQLKKSPEALKCR 961
E++++ E + + + A EE P++ P+ K + E KSP K
Sbjct: 570 EEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEA--------KSPAEAKSP 621
Query: 962 LTEGSERLPRRYSEGDRAVLRGFSESSEEEEEPESPRSSSPPILTKPTLKRKKPFLHRRR 1021
+ E + P ++A S + EE + PE +S P K K P +
Sbjct: 622 VKE-EAKSPAEVKSPEKAK----SPTKEEAKSPEKAKSPEKEEAKSPE-KAKSPVKAEAK 675
Query: 1022 RVRKRKHHNSSVVTETISETTEVLDEPFEDSDSERPMPRLEPTFEIDEEEEEEDENELFP 1081
K K S V E +++ E P ++ +++ P P +EE + E P
Sbjct: 676 SPEKAK---SPVKAE--AKSPEKAKSPVKE-EAKSPEKAKSPV----KEEAKSPEKAKSP 725
Query: 1082 REYFRRLSSQDVLRCQSSSKRKSKDEEEDEESDDADDTPILKPVSLLRKRDVKNSPLEPD 1141
+ ++ K KS +EE + + A K + DVK+ P+
Sbjct: 726 VKE----------EAKTPEKAKSPVKEEAKSPEKA------KSPEKAKTLDVKS----PE 765
Query: 1142 TSTPLKKKKGWPKGKSRKPIHWKKRPGRKPGFKLSREIMPVSTQACVIEPIVSIPKAGRK 1201
TP K++ P K P ++ V E + K+ K
Sbjct: 766 AKTPAKEEARSPADK-----------------------FPEKAKSPVKEEV----KSPEK 798
Query: 1202 PKIQESEETVEPKEDMPLPEE-----RKEEEEMQAEAEEAEEGEEEDAASSEVPAASPAD 1256
K E+ P++++P EE ++EE+ + + +E + EE+ A + D
Sbjct: 799 AKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKD 858
Query: 1257 S--SNSPETETKEPEVEEEE----EKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQ 1310
S +P+ E +P+VEE++ EKP+ S+ + + EE + + + P PE+E A E +
Sbjct: 859 SKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKE 918
Query: 1311 NDDHDADDE------DDGHLESTKK--KELEEQPTREDVKEEPGVQESFLDANMQKSREK 1362
+ E DD + K ++ E P ++D KEE + K+ K
Sbjct: 919 DAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPE----EKPKTEAK 974
Query: 1363 IKDKEETELDSEEEQPSHDTSVVSEQMAGSEDDHEEDSHTKEELIELK 1410
K+ ++T L E +P +E+ S ++DS E+ E K
Sbjct: 975 AKEDDKT-LSKEPSKPK------AEKAEKSSSTDQKDSKPPEKATEDK 1015
Score = 83.2 bits (204), Expect = 2e-15
Identities = 121/564 (21%), Positives = 224/564 (39%), Gaps = 60/564 (10%)
Query: 786 VSEEEEEEAEE--------GENEEPQCQERELEISVGKSVSHENKEQDSYSVESEKKP-- 835
V+EEEE+EA+E GE EE + E E + + + KE S E K P
Sbjct: 470 VTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAE 529
Query: 836 -------EVMAPVSSTRLSKQVLPHDSLPANSQPSRRGRWGRKNRKTQERFGDKDSKLLL 888
E +P K P A S P + + + E + +K
Sbjct: 530 AKSPEKEEAKSPAEVKSPEKAKSPAKE-EAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPA 588
Query: 889 EETSSAPQEQYGECGEKSEATQEQYTESEEQLVASEE--QPSQDGKPDLPKRRLSEGVEP 946
+E + +P E KS +E + +E + EE P++ P+ K E E
Sbjct: 589 KEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKE--EA 646
Query: 947 WRGQLKKSPEALKCRLTEGSE---RLPRRYSEGDRAVLRGFSESSEE-----EEEPESPR 998
+ KSPE + + E ++ + + E ++ ++ ++S E+ +EE +SP
Sbjct: 647 KSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPE 706
Query: 999 SSSPPIL--TKPTLKRKKPFLHRRRRVRKRKHHNSSVVTETIS-------ETTEVLDEPF 1049
+ P+ K K K P + K K S V E S E + LD
Sbjct: 707 KAKSPVKEEAKSPEKAKSPVKEEAKTPEKAK---SPVKEEAKSPEKAKSPEKAKTLDVKS 763
Query: 1050 EDSDSERPMPRLEPTFEIDEEEEEEDENELFPREYFRRLSSQDVLRCQSSSKRKSKDEEE 1109
++ + P + E+ + + E+ E + +D + +K + +
Sbjct: 764 PEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSP 823
Query: 1110 DEESDDADDTPILKPVSLLRKRDVKNSPLEPDTSTPL-KKKKGWPKGKSRKPIHWKKRPG 1168
+E + + + +P +K + + +P P T KK+ PK ++ KP K
Sbjct: 824 VKEEEKPQEVKVKEPP---KKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKP---KVEEK 877
Query: 1169 RKPGFKLSREIMPVSTQACVIEPIVSIPKAGRK-PKIQESEETVEPKEDMPLPEERKEEE 1227
++P + +E V + E +P ++ P E +E +PKE + ++ ++
Sbjct: 878 KEPAVEKPKE-SKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDA 936
Query: 1228 EMQAEAEEAEEGEE--EDAASSEVPAASPADSSNSPETETKEPE----VEEEEEKPRVSE 1281
+ + ++ AE+ E E + E A P + P+TE K E + +E KP+ +
Sbjct: 937 KAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEK---PKTEAKAKEDDKTLSKEPSKPKAEK 993
Query: 1282 EQRQSEEEQQELEEPEPEEEEDAA 1305
++ S +Q++ + PE E+ AA
Sbjct: 994 AEKSSSTDQKDSKPPEKATEDKAA 1017
Score = 79.7 bits (195), Expect = 3e-14
Identities = 113/517 (21%), Positives = 199/517 (38%), Gaps = 93/517 (17%)
Query: 1197 KAGRKPKIQES--EETV---EPKEDMPLPEERKEEEEMQAEAEEAEE---GEEEDAASSE 1248
K+ K K+ E +ETV E E+ + EE EEEE +A+ EE +E GEEE+A E
Sbjct: 439 KSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGE 498
Query: 1249 VPAASP-ADSSNSPETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAE 1307
SP A+ + SPE E K P V+EE + P + + EE + E PE+ + A E
Sbjct: 499 EETKSPPAEEAASPEKEAKSP-VKEEAKSP-AEAKSPEKEEAKSPAEVKSPEKAKSPAKE 556
Query: 1308 TAQNDDHDADDEDDGHLESTKKKELEEQPTREDVKEEPGVQESFLDANMQKSREKIKD-- 1365
A K + P +E+ K V KS EK K
Sbjct: 557 EA------------------KSPPEAKSPEKEEAKSPAEV----------KSPEKAKSPA 588
Query: 1366 KEETELDSEEEQPSHDTSVVSEQMAGSEDDHEEDSHTKEELIELKEEEEIPHSELDLETV 1425
KEE + +E + P S V E+ ++ E S KEE S ++++
Sbjct: 589 KEEAKSPAEAKSPEKAKSPVKEE---AKSPAEAKSPVKEE----------AKSPAEVKSP 635
Query: 1426 QAVQSLTQEESSEHEGAYQDCEETLAACQTLQSYTQAD-EDPQMSMVEDCHASEHNSPIS 1484
+ +S T+EE+ E A +E + + +S +A+ + P+ + ++
Sbjct: 636 EKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAK 695
Query: 1485 SVQSHPSQSVRSVSSPNVPALESGYTQISPEQGSLSAPSMQNMETSPMMDVPSVSDHSQQ 1544
S ++S SP +S SP + P SP+ + + ++
Sbjct: 696 SPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAK---SPVKEEAKSPEKAKS 752
Query: 1545 VVDSGFSDLGSIESTTENYENPSSYDSTMGGSICGNSSSQSSCSYGGLSSSSSLTQSSCV 1604
+ D+ S E+ T E S + ++
Sbjct: 753 PEKAKTLDVKSPEAKTPAKEEARS------------------------PADKFPEKAKSP 788
Query: 1605 VTQQMASMGSSCSMMQQSSVQPAANCSIK-----------SPQSCVVERPPSNQQQQPPP 1653
V +++ S + S +++ + P K PQ V+ PP +++ P
Sbjct: 789 VKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAP 848
Query: 1654 PPPQQPQPPPPQPQPAPQPPPPQQQPQQQPQPQPQQP 1690
P+ + + + AP+ P+ + +++ +P ++P
Sbjct: 849 ATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKP 885
Score = 71.6 bits (174), Expect = 7e-12
Identities = 91/460 (19%), Positives = 171/460 (37%), Gaps = 70/460 (15%)
Query: 1025 KRKHHNSSVVTETISETTEVLDEPFEDSDSERPMPRLEPTFEIDEEEEEEDENELFPREY 1084
K K V E + T +++E E++ + T E+ EEEE+E + E
Sbjct: 437 KVKSEEKIKVVEKSEKETVIVEEQTEET---------QVTEEVTEEEEKEAKEE------ 481
Query: 1085 FRRLSSQDVLRCQSSSKRKSKDEE--EDEESDDADDTPILKPVSLLRKRDVKNSPLEPDT 1142
+ K+EE E+EE++ ++ + K+ P E +
Sbjct: 482 ------------------EGKEEEGGEEEEAEGGEE-------------ETKSPPAE-EA 509
Query: 1143 STPLKKKKGWPKGKSRKPIHWKKRPGRKPGFKLSREIMPVSTQACVIEPIVSIPKAGRKP 1202
++P K+ K K +++ P K P ++ + P ++ E S P+A + P
Sbjct: 510 ASPEKEAKSPVKEEAKSPAE-AKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEA-KSP 567
Query: 1203 KIQESEETVEPKEDMPLPEERKEEEEMQAEAEEAEEGEE--EDAASSEVPAASPADSSNS 1260
+ +E++ E K KEE + AEA+ E+ + ++ A S A SP
Sbjct: 568 EKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAK 627
Query: 1261 PETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPE----PEEEEDAAAETAQNDDHDA 1316
E K PE + K ++ E++E + PE P + E + E A++
Sbjct: 628 SPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVK-- 685
Query: 1317 DDEDDGHLESTKKKELEEQPTREDVKEEPGVQESFLDANMQKSREKIKDKEETELDSEEE 1376
K E + P +E+ K + + + K KEE + + +
Sbjct: 686 --------AEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAK 737
Query: 1377 QPSHDTSVVSEQMAGSEDDHEEDSHTKEELIELKEEEEIPHSELDLETVQAVQSLTQEES 1436
P + + E+ E D + E KEE P + + V+ +
Sbjct: 738 SPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPE 797
Query: 1437 SEHEGAYQDC---EETLAACQTLQSYTQADEDPQMSMVED 1473
+D E+ + + ++S + +E PQ V++
Sbjct: 798 KAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKE 837
Score = 67.0 bits (162), Expect = 2e-10
Identities = 116/548 (21%), Positives = 209/548 (38%), Gaps = 63/548 (11%)
Query: 983 GFSESSEEEEEPES--PRSSSPPI--LTKPTLKRKKPFLHRRRRVRKRKHHNSSVVTETI 1038
G E EEEE E + SPP P + K P + + K S E
Sbjct: 483 GKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAK----SPEKEEA 538
Query: 1039 SETTEVLDEPFEDSDSERPMPRLEPTFEIDEEEEEEDENELFPREYFRRLSSQDVLR-CQ 1097
EV P + + + P + E+EE + E+ E + + ++ +
Sbjct: 539 KSPAEV-KSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAE 597
Query: 1098 SSSKRKSKDEEEDEESDDAD-DTPI---LKPVSLLRKRDVKNSPLEPDTSTPLKKKKGWP 1153
+ S K+K ++E A+ +P+ K + ++ + SP + + +P K K P
Sbjct: 598 AKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKS--P 655
Query: 1154 KGKSRKPIHWKKRPGRKPGFKLSREIMPVSTQACVIEPIVSIPKAGRKPKIQESEETVEP 1213
+ + K K P + + PV +A K+ K K EE P
Sbjct: 656 EKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEA----------KSPEKAKSPVKEEAKSP 705
Query: 1214 -KEDMPLPEERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSNSPETETKEPEVEE 1272
K P+ EE K E+ ++ +E + E+ + + A SP + + SPE + K +V+
Sbjct: 706 EKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSP-EKAKSPE-KAKTLDVKS 763
Query: 1273 EEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDEDDGHLESTKKKEL 1332
E K EE R ++ E + P +EE + E A++ L+ K
Sbjct: 764 PEAKTPAKEEARSPADKFPE-KAKSPVKEEVKSPEKAKSP-----------LKEDAKAPE 811
Query: 1333 EEQPTRED----VKEEPGVQESFLDANMQKSRE-------KIKDKEETELDSEEEQPSHD 1381
+E P +E+ VKEE QE + +K+ E K ++K++++ + ++ +
Sbjct: 812 KEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPK 871
Query: 1382 TSVVSEQMAGSEDDHEEDSHTKEELIELKEEEEIPHSELDLETVQAVQSLTQEESSEHEG 1441
V ++ E E K+E E K++ P E + V+ + +E +E
Sbjct: 872 PKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAK-VEVKEDAKPKEKTEVAK 930
Query: 1442 AYQD----------CEETLAACQTLQSYTQADEDPQMSMVEDCHASEHNSPISSVQSHPS 1491
D E+ AA + + + + P+ + A E + +S S P
Sbjct: 931 KEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPK 990
Query: 1492 QSVRSVSS 1499
SS
Sbjct: 991 AEKAEKSS 998
>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
sapiens]
Length = 1362
Score = 88.6 bits (218), Expect = 6e-17
Identities = 118/539 (21%), Positives = 201/539 (37%), Gaps = 81/539 (15%)
Query: 1201 KPKIQESEETVEPKEDMPLPEERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSNS 1260
KPK +E ++ + KE EE +E ++ +A+ ++ ++ ++++S V PA +
Sbjct: 535 KPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEPPPKKTKKNNSSNSNVSKKEPAPMKSK 594
Query: 1261 PETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDD----HDA 1316
P T E E EE++ KP EE+RQ + +L P E+ Q+ + +
Sbjct: 595 PPP-TYESE-EEDKCKPMSYEEKRQLSLDINKL----PGEKLGRVVHIIQSREPSLKNSN 648
Query: 1317 DDEDDGHLESTKKKELEEQPTREDVKEEPGVQESFLDANMQKSREKIKDKEETELDSEEE 1376
DE + E+ K L E E ++ + ++K R+ +K + S +
Sbjct: 649 PDEIEIDFETLKPSTLREL-------------ERYVTSCLRKKRKPQAEKVDVIAGSSKM 695
Query: 1377 QPSHDTSVVSEQMAGSEDDHEEDSHTKEELIELKEEEEIPHSELDLETVQAVQSLTQEES 1436
+ SE + SE + ++ E+ +++ P +E+
Sbjct: 696 KGFSS----SESESSSESSSSDSEDSETEMAPKSKKKGHPG---------------REQK 736
Query: 1437 SEHEGAYQDCEETLAACQTLQSYTQADEDPQMSMVEDCHASEHNSPISSVQSHPSQSVRS 1496
H +Q ++ A P + + P S P Q+ +
Sbjct: 737 KHHHHHHQQMQQAPAPVPQQPPPPPQQPPPPPPPQQQ----QQPPPPPPPPSMPQQAAPA 792
Query: 1497 VSSPNVPALESGYTQISPE-QGSLSAPSMQNMETSPMMDVPSVSDHSQQVVDSG------ 1549
+ S P + + + P+ GS+ P + + P + H Q +
Sbjct: 793 MKSSPPPFIATQVPVLEPQLPGSVFDPIGHFTQPILHLPQPELPPHLPQPPEHSTPPHLN 852
Query: 1550 ----FSDLGSIESTTENYENPSSYDSTMGGSICGNSSSQSSCSYGGLSSSSSLTQSSCVV 1605
S + + PS+ + + + + + L + Q V+
Sbjct: 853 QHAVVSPPALHNALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVL 912
Query: 1606 TQQ-------MASMGSSCSMMQQSSVQPAA----NCSIKSPQSCVVERPP-----SNQQQ 1649
+ + SM + Q VQP + ++S + PP QQ
Sbjct: 913 LEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQ 972
Query: 1650 QPPPPPPQQPQPPPPQPQPAPQPPPPQQQP-------QQQPQPQPQQPPPPPPPQQQPP 1701
QPPPPPP QPQ PPPQ Q P P P QP QQ P PQ QQPP PPP QQ PP
Sbjct: 973 QPPPPPPPQPQ-PPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPPGQQPPP 1030
Score = 75.9 bits (185), Expect = 4e-13
Identities = 71/234 (30%), Positives = 95/234 (40%), Gaps = 52/234 (22%)
Query: 1647 QQQQPPPPPPQQPQPPPPQPQPAPQPPPPQQQPQQQPQPQPQQPPPPPPPQQQPPLSQCS 1706
Q QQ P P PQQP PPP QP P PPPPQQQ QQPPPPPPP P + +
Sbjct: 745 QMQQAPAPVPQQPPPPPQQPPP---PPPPQQQ---------QQPPPPPPPPSMPQQAAPA 792
Query: 1707 MNNSFTPAPMI-MEIPESGSTGNISIYERIPGDFGAGSYSQPSATFSLAKLQQLTNTIMD 1765
M +S P P I ++P S+++ I G ++QP + L +
Sbjct: 793 MKSS--PPPFIATQVPVLEPQLPGSVFDPI------GHFTQP--------ILHLPQPELP 836
Query: 1766 PH-AMPYSHS--PAVTSYATSVSLSNTGLAQLAPSHPLAGTPQAQATMTPPPNLASTTMN 1822
PH P HS P + +A +S L P P + +A A P + +
Sbjct: 837 PHLPQPPEHSTPPHLNQHAV---VSPPALHNALPQQPSRPSNRAAALPPKPARPPAVSPA 893
Query: 1823 LT-SPLLQCNMSATNIGIPHTQRLQGQMPVKGHISIRSKSAPLPSAAAHQQQLY 1875
LT +PLL Q M + + + P P + Q QLY
Sbjct: 894 LTQTPLLP----------------QPPMAQPPQVLLEDEEPPAPPLTSMQMQLY 931
Score = 75.5 bits (184), Expect = 5e-13
Identities = 68/258 (26%), Positives = 99/258 (38%), Gaps = 28/258 (10%)
Query: 1640 VERPPSNQQQQPPPPPPQQPQPPPPQPQPAPQPPPPQQQPQQQPQPQPQQPPPPPPPQQQ 1699
+++ P+ QQPPPPP Q P PPPPQ Q P PPPP QQ P + PPP Q
Sbjct: 746 MQQAPAPVPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIATQV 805
Query: 1700 PPLSQCSMNNSFTP----APMIMEIPESGSTGNISIYERIPGDFGAGSYSQPSATFSLAK 1755
P L + F P I+ +P+ + + P + + A S
Sbjct: 806 PVLEPQLPGSVFDPIGHFTQPILHLPQP----ELPPHLPQPPEHSTPPHLNQHAVVSPPA 861
Query: 1756 LQQLTNTIMDPHAMPYSHSPAVTSYATSVSLSNTGLAQ--LAPSHPLAGTPQAQATMTPP 1813
L N + + P + + A+ + L Q L P P+A PQ P
Sbjct: 862 LH---NALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEP 918
Query: 1814 PNLASTTMNLTSPLLQCNMSATNIGIPHTQRLQGQMPVKGHISIRSK---SAPLPSAAAH 1870
P T+M + L Q Q++Q P+ + ++S+ P P +
Sbjct: 919 PAPPLTSMQMQLYLQQ------------LQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSV 966
Query: 1871 QQQLYGRSPSAVAMQAGP 1888
QQQL + P Q P
Sbjct: 967 QQQLQQQPPPPPPPQPQP 984
Score = 73.2 bits (178), Expect = 2e-12
Identities = 116/559 (20%), Positives = 210/559 (37%), Gaps = 77/559 (13%)
Query: 1190 EPIVSIPKAGRKP--KIQESEETVEPKEDMPLPEERKEEEEMQAEAEEAEEGEEEDAASS 1247
EP+V++ P K+ + + D + ++ + A+ E +E+ A
Sbjct: 463 EPVVAVSSPAVPPPTKVVAPPSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQEQLKAVH 522
Query: 1248 EVPAASPADSSNSPETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEE------- 1300
E AA N P+ + K+ + +++E+ R E + E ++ + +EP P++
Sbjct: 523 EQLAALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVE---ENKKSKAKEPPPKKTKKNNSS 579
Query: 1301 ------EEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQPTRE---DVKEEPGVQESF 1351
+E A ++ +++++ED K K + + R+ D+ + PG +
Sbjct: 580 NSNVSKKEPAPMKSKPPPTYESEEED-------KCKPMSYEEKRQLSLDINKLPGEKLGR 632
Query: 1352 LDANMQKSREKIKDKEETELDSEEEQPSHDTSVVSEQMAGSEDDHEEDSHTKEELIELKE 1411
+ +Q +K+ E++ + E T E+ S K+ + ++
Sbjct: 633 VVHIIQSREPSLKNSNPDEIEIDFETLKPSTLRELERYVTS-------CLRKKRKPQAEK 685
Query: 1412 EEEIPHSELDLETVQAVQSLTQEESSEHEGAYQDCEETLAACQTLQSYTQADEDPQMSMV 1471
+ I S ++ S E SSE + + ET A ++ + E +
Sbjct: 686 VDVIAGSS----KMKGFSSSESESSSESSSSDSEDSETEMAPKSKKKGHPGREQKKHHHH 741
Query: 1472 EDCHASEHNSPISSVQSHPSQSVRSVSSPNVPALESGYTQISPEQGSLSAPSMQNMETSP 1531
+ +P+ P Q P P + P S+ + M++SP
Sbjct: 742 HHQQMQQAPAPVPQQPPPPPQQ----PPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSP 797
Query: 1532 MMDVPS-VSDHSQQVVDSGFSDLGSIESTTENY---ENPSSYDSTMGGSICGNSSSQSSC 1587
+ + V Q+ S F +G + E P S + + +
Sbjct: 798 PPFIATQVPVLEPQLPGSVFDPIGHFTQPILHLPQPELPPHLPQPPEHSTPPHLNQHAVV 857
Query: 1588 SYGGLSSSSSLTQSSCVVTQQMASMGSSCSMMQQSSVQPAANCSIKSPQSCVVERPPSNQ 1647
S L ++ L Q + + A++ + + +V PA + PQ + + P
Sbjct: 858 SPPALHNA--LPQQPSRPSNRAAALPPKPA--RPPAVSPALTQTPLLPQPPMAQPPQVLL 913
Query: 1648 QQQPPPPPP-------------QQPQPPPP---------QPQPAPQPPPPQQQPQQQPQP 1685
+ + PP PP Q+ QPP P QP P P PPPP QQQ Q
Sbjct: 914 EDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPP-PLPPPPHPSVQQQLQ- 971
Query: 1686 QPQQPPPPPPPQQQPPLSQ 1704
QQPPPPPPPQ QPP Q
Sbjct: 972 --QQPPPPPPPQPQPPPQQ 988
Score = 53.9 bits (128), Expect = 2e-06
Identities = 33/89 (37%), Positives = 37/89 (41%), Gaps = 6/89 (6%)
Query: 1643 PPSNQQQQPPPPPPQQPQPPPPQPQPAPQPPPPQQQPQQQP-----QPQPQQPPPPPPPQ 1697
P + Q PP QP PPP Q P P P Q P PQP Q PPP PPQ
Sbjct: 197 PNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQ 256
Query: 1698 QQPPLSQCSMNNSFTPAPMIMEIPESGST 1726
QPP + P P+I P+ T
Sbjct: 257 PQPPPAPAPQPVQSHP-PIIAATPQPVKT 284
Score = 53.9 bits (128), Expect = 2e-06
Identities = 29/77 (37%), Positives = 30/77 (38%), Gaps = 18/77 (23%)
Query: 1635 PQSCVVERPPSNQQQQPPPPPPQQPQPP------------------PPQPQPAPQPPPPQ 1676
P + PP Q QP PPP Q P PPQP P P PPQ
Sbjct: 197 PNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQ 256
Query: 1677 QQPQQQPQPQPQQPPPP 1693
QP P PQP Q PP
Sbjct: 257 PQPPPAPAPQPVQSHPP 273
Score = 48.1 bits (113), Expect = 8e-05
Identities = 24/49 (48%), Positives = 26/49 (53%), Gaps = 1/49 (2%)
Query: 1645 SNQQQQPPPPPPQQP-QPPPPQPQPAPQPPPPQQQPQQQPQPQPQQPPP 1692
S QQPPPP QQP PPP Q P PQP PQQ Q P+ + P
Sbjct: 1005 STHIQQPPPPQGQQPPHPPPGQQPPPPQPAKPQQVIQHHHSPRHHKSDP 1053
Score = 45.8 bits (107), Expect = 4e-04
Identities = 38/122 (31%), Positives = 49/122 (40%), Gaps = 30/122 (24%)
Query: 1617 SMMQQSSVQPAANCSIKSPQSCVVERPPSNQQQQPPPPP------------PQQPQP--- 1661
S+ QQ QP P +PP QQ QPPP P Q P P
Sbjct: 965 SVQQQLQQQPP-------PPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQ 1017
Query: 1662 PPPQPQPAPQPPPPQ-QQPQQQPQPQPQQPPPPPPPQQQPPLSQCSMNNSFTPAPMIMEI 1720
PP P P QPPPPQ +PQQ Q P + P S + + P+P+++
Sbjct: 1018 QPPHPPPGQQPPPPQPAKPQQVIQHHHS-----PRHHKSDPYSTGHLREA--PSPLMIHS 1070
Query: 1721 PE 1722
P+
Sbjct: 1071 PQ 1072
Score = 44.3 bits (103), Expect = 0.001
Identities = 61/285 (21%), Positives = 123/285 (43%), Gaps = 31/285 (10%)
Query: 1035 TETISETTEVLDEPFEDSDSERPMPRLEPTFEIDEEEEEEDENELFPREYFRRLSSQDVL 1094
+++ S+++ D +DS+ ER RL E + E+ P++ + +D
Sbjct: 486 SDSSSDSSSDSDSSTDDSEEERAQ-RLAELQEQLKAVHEQLAALSQPQQNKPKKKEKDKK 544
Query: 1095 RCQSSSKRKSKDEEEDEESDDADDTPILKPVSLLRKRDVKNSPLEPDTSTPLKKKKGWPK 1154
+ K K K+E E+ + A + P K +K + NS + P+K K P
Sbjct: 545 E-KKKEKHKRKEEVEENKKSKAKEPPPKKT----KKNNSSNSNVSKKEPAPMKSKPP-PT 598
Query: 1155 GKSR-----KPIHWKKRP------GRKPGFKLSREIMPVSTQACVIEPIVSIPKAGRKPK 1203
+S KP+ ++++ + PG KL R + + ++ EP + K +
Sbjct: 599 YESEEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSR----EPSL---KNSNPDE 651
Query: 1204 IQESEETVEPKEDMPLPEE----RKEEEEMQAEAEEAEEGEEE--DAASSEVPAASPADS 1257
I+ ET++P L +++ + QAE + G + +SSE ++S + S
Sbjct: 652 IEIDFETLKPSTLRELERYVTSCLRKKRKPQAEKVDVIAGSSKMKGFSSSESESSSESSS 711
Query: 1258 SNSPETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEE 1302
S+S ++ET+ +++ P +++ QQ + P P ++
Sbjct: 712 SDSEDSETEMAPKSKKKGHPGREQKKHHHHHHQQMQQAPAPVPQQ 756
Score = 42.4 bits (98), Expect = 0.005
Identities = 60/299 (20%), Positives = 121/299 (40%), Gaps = 45/299 (15%)
Query: 1088 LSSQDVLRCQSSSKRKSKDEEEDEESDDADDTPILKPVSLLRKRDVK-NSPL---EPDTS 1143
+ S + + QS + + + + + +++P L+ ++ K +SP+ EP +
Sbjct: 1068 IHSPQMSQFQSLTHQSPPQQNVQPKKQELRAASVVQPQPLVVVKEEKIHSPIIRSEPFSP 1127
Query: 1144 TPLKKKKGWPKGKSRKPIHWKKRPGRKPGFKLSREIMPVSTQACVIEPIV-SIPKAGRKP 1202
+ + P+ + P+H +RP E+ PV VI P + P G
Sbjct: 1128 SLRPEPPKHPES-IKAPVHLPQRP----------EMKPVDVGRPVIRPPEQNAPPPGAPD 1176
Query: 1203 KIQESEET---VEPKEDMPL----------------PEERKEE-----EEMQAEAEEAEE 1238
K ++ +E V PK+D+ + P + E+ + A E EE
Sbjct: 1177 KDKQKQEPKTPVAPKKDLKIKNMGSWASLVQKHPTTPSSTAKSSSDSFEQFRRAAREKEE 1236
Query: 1239 GEEEDAASSEVPAASPADSSNSPETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEP 1298
E+ A +E A + ++E E E+ + E +R+ E++QQ+ +E +
Sbjct: 1237 REKALKAQAE-HAEKEKERLRQERMRSREDEDALEQARRAHEEARRRQEQQQQQRQEQQQ 1295
Query: 1299 EEEEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQPTREDVKEEPGVQESFLDANMQ 1357
++++ AAA A + L+ +++EL + RE + + +D N Q
Sbjct: 1296 QQQQQAAAVAAAATPQAQSSQPQSMLD--QQRELARK--REQERRRREAMAATIDMNFQ 1350
Score = 41.6 bits (96), Expect = 0.008
Identities = 30/102 (29%), Positives = 39/102 (38%), Gaps = 23/102 (22%)
Query: 1640 VERPPSNQQQQPPPPPP-QQPQPP-PPQPQPAPQ---------------------PPPPQ 1676
+++PP Q QQPP PPP QQP PP P +PQ Q P P
Sbjct: 1008 IQQPPPPQGQQPPHPPPGQQPPPPQPAKPQQVIQHHHSPRHHKSDPYSTGHLREAPSPLM 1067
Query: 1677 QQPQQQPQPQPQQPPPPPPPQQQPPLSQCSMNNSFTPAPMIM 1718
Q Q Q PP QP + + P P+++
Sbjct: 1068 IHSPQMSQFQSLTHQSPPQQNVQPKKQELRAASVVQPQPLVV 1109
Score = 38.9 bits (89), Expect = 0.051
Identities = 55/284 (19%), Positives = 108/284 (38%), Gaps = 40/284 (14%)
Query: 889 EETSSAPQEQYGECGEKSEATQEQYTESEEQLVASEEQPSQDGKP--DLPKRRLSEGVEP 946
+ +S + + + E ++ E +EQL A EQ + +P + PK++ + E
Sbjct: 487 DSSSDSSSDSDSSTDDSEEERAQRLAELQEQLKAVHEQLAALSQPQQNKPKKKEKDKKEK 546
Query: 947 WRGQLKKSPEALKCRLTEGSERLPRRYSEGDRAVLRGFSESSEEEEEPESPRSSSPPILT 1006
+ + K+ E + + ++ E P++ + + S S+ ++EP +S PP
Sbjct: 547 KKEKHKRKEEVEENKKSKAKEPPPKKTKKNNS------SNSNVSKKEPAPMKSKPPPTYE 600
Query: 1007 KPTLKRKKPFLHRRRRVRKRKHHNSSVVTETISETTEVLDEPFEDSDSERPMPRLEPTFE 1066
+ KP + + R+ + + E + ++ S P + E
Sbjct: 601 SEEEDKCKPMSYEEK--RQLSLDINKLPGEKLGRVVHII-------QSREPSLKNSNPDE 651
Query: 1067 IDEEEEEEDENELFPREYF--------RRLSSQDVLRCQSSSKRKSKDEEEDEESDDADD 1118
I+ + E + L E + R+ ++ V SSK K E E S ++
Sbjct: 652 IEIDFETLKPSTLRELERYVTSCLRKKRKPQAEKVDVIAGSSKMKGFSSSESESSSESSS 711
Query: 1119 TPILKPVSLLRKRDVKNSPLEPDTSTPLKKKKGWPKGKSRKPIH 1162
+ D ++S E P KKKG P + +K H
Sbjct: 712 S------------DSEDSETE---MAPKSKKKGHPGREQKKHHH 740
Score = 38.1 bits (87), Expect = 0.087
Identities = 34/111 (30%), Positives = 40/111 (36%), Gaps = 42/111 (37%)
Query: 1632 IKSPQSCVVERPPSNQQQQPPPPPPQQPQPPP-PQPQPAPQPPP-----PQQ-------- 1677
+++P VV PP Q Q PPP P QPQPPP P PQP PP PQ
Sbjct: 234 VQTPVMTVV--PP--QPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVK 289
Query: 1678 -----------QPQQQPQPQPQQP-------------PPPPPPQQQPPLSQ 1704
P +P P +P P PP + P Q
Sbjct: 290 RKADTTTPTTIDPIHEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQ 340
Score = 36.2 bits (82), Expect = 0.33
Identities = 25/99 (25%), Positives = 38/99 (38%), Gaps = 6/99 (6%)
Query: 1631 SIKSPQSCVVERPPSNQQQQPPPPPPQQPQPPPPQPQPAPQPPPPQQQPQQQPQP----- 1685
++ PQ P Q Q PP P PQ Q PP PQP ++ +++
Sbjct: 240 TVVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTT 299
Query: 1686 -QPQQPPPPPPPQQQPPLSQCSMNNSFTPAPMIMEIPES 1723
P PP PP+ + +S P ++P+S
Sbjct: 300 IDPIHEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDS 338
Score = 33.5 bits (75), Expect = 2.1
Identities = 34/131 (25%), Positives = 54/131 (41%), Gaps = 26/131 (19%)
Query: 1621 QSSVQPAAN----CSIKSPQSCVV---ERPPSNQQQQPPPPPPQQPQPPPPQPQPAPQPP 1673
Q +VQP S+ PQ VV E+ S + P P +P+PP P+ P
Sbjct: 1086 QQNVQPKKQELRAASVVQPQPLVVVKEEKIHSPIIRSEPFSPSLRPEPPK-HPESIKAPV 1144
Query: 1674 PPQQQPQQQP--------QPQPQQPPPPPPP-----QQQP-----PLSQCSMNNSFTPAP 1715
Q+P+ +P +P Q PPP P +Q+P P + N + A
Sbjct: 1145 HLPQRPEMKPVDVGRPVIRPPEQNAPPPGAPDKDKQKQEPKTPVAPKKDLKIKNMGSWAS 1204
Query: 1716 MIMEIPESGST 1726
++ + P + S+
Sbjct: 1205 LVQKHPTTPSS 1215
Score = 31.6 bits (70), Expect = 8.2
Identities = 54/278 (19%), Positives = 99/278 (35%), Gaps = 55/278 (19%)
Query: 1036 ETISETTEVLDEPFEDSDSERPMPRLEPTFEIDEEEEEEDEN------ELFPREYFRRLS 1089
+ + E L +P ++ ++ + E E + +EE +EN E P++ + S
Sbjct: 519 KAVHEQLAALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEPPPKKTKKNNS 578
Query: 1090 SQDVLRCQSSSKRKSKDEE--EDEESDDADDTPILKPVSLLRKRDVKNSPLEPDTSTPLK 1147
S + + + KSK E EE D KP+S KR + S +
Sbjct: 579 SNSNVSKKEPAPMKSKPPPTYESEEEDKC------KPMSYEEKRQL---------SLDIN 623
Query: 1148 KKKGWPKGK------SRKPIHWKKRPGRKPGFKLSREIMPVSTQACVIEPIVSIPKAGRK 1201
K G G+ SR+P P ++ E + ST + + S + RK
Sbjct: 624 KLPGEKLGRVVHIIQSREPSLKNSNPDE---IEIDFETLKPSTLRELERYVTSCLRKKRK 680
Query: 1202 PKIQESEETVEPKEDMPLPEERKEEEEMQAEAEEAEEGEEEDAASS-------------- 1247
P+ E + + M + E ++ + ++E+ E E A S
Sbjct: 681 PQA-EKVDVIAGSSKMKGFSSSESESSSESSSSDSEDSETEMAPKSKKKGHPGREQKKHH 739
Query: 1248 --------EVPAASPADSSNSPETETKEPEVEEEEEKP 1277
+ PA P P+ P +++++ P
Sbjct: 740 HHHHQQMQQAPAPVPQQPPPPPQQPPPPPPPQQQQQPP 777
>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 [Homo
sapiens]
Length = 916
Score = 86.7 bits (213), Expect = 2e-16
Identities = 105/455 (23%), Positives = 185/455 (40%), Gaps = 41/455 (9%)
Query: 989 EEEEEPESPRSSSPPILTKPTLKRKKPFLHRRRRVRKRKHHNSSVVTETISETTEVLDEP 1048
EE++E + P + +K P V++ + E E E DE
Sbjct: 486 EEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEE---EEGQEEEEEEDEG 542
Query: 1049 FEDSDSERPMPRLEPTFEIDEEEEEEDENELFPREYFRRLSSQDVLRCQSSSKRKSKDEE 1108
+ +E E + E +E E+EE E E + + + K + K EE
Sbjct: 543 AKSDQAEEGGSEKEGSSEKEEGEQEEGETEAE--------AEGEEAEAKEEKKVEEKSEE 594
Query: 1109 EDEESDDADDTPILKPVSLLRKRDVKNSPLEPDTSTPLKKKKGWPKGKSRKPIHWKKRPG 1168
+ + D + KP K V SP+E +P+ K KGKS P + G
Sbjct: 595 VATKEELVADAKVEKPEKA--KSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKG 652
Query: 1169 RKPGFKLSREIMPVSTQACVIEPIVSIPKAGRKPKIQESEETVEPKEDMPLPEERKEEEE 1228
+ P K PV + + + + P + E + K ++ E+++EEE+
Sbjct: 653 KSPVPK-----SPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEK 707
Query: 1229 MQAEAEEAEEGEEEDAASSEVPAASPADSSNSPE------TETKEPEVE-EEEEKPRVSE 1281
EA + E+ E+++ +VP A+S E T TK +V E+E K
Sbjct: 708 EVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKP 767
Query: 1282 EQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQPTRE-- 1339
Q++ E+E+ E EE D A+ ++ +D + E +G KE EQ T+E
Sbjct: 768 LQQEKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEG-------KEEVEQETKEKG 820
Query: 1340 -DVKEEPGVQESFLD---ANMQKSREKIKDK---EETELDSEEEQPSHDTSVVSEQMAGS 1392
+EE GV + LD A+ +K +K ++K +T E T +++ + +
Sbjct: 821 SGREEEKGVVTNGLDLSPADEKKGGDKSEEKVVVTKTVEKITSEGGDGATKYITKSVTVT 880
Query: 1393 EDDHEEDSHTKEELIELKEEEEIPHSELDLETVQA 1427
+ E + +E+L+ K+ E++ + E Q+
Sbjct: 881 QKVEEHEETFEEKLVSTKKVEKVTSHAIVKEVTQS 915
Score = 81.3 bits (199), Expect = 9e-15
Identities = 115/509 (22%), Positives = 195/509 (38%), Gaps = 88/509 (17%)
Query: 984 FSESSEEEEEPESPRSSSPPILTKPTLKRKKPFLHRRRRVRKRKHHNSSVVTETISETTE 1043
F E EE + E +S LT T + ++ + K E ++
Sbjct: 452 FVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKS 511
Query: 1044 VLDEPFEDSDSERPMPRLEPTFEIDEEEEE--------------EDENELFPREYFRRLS 1089
+ + E E E +EEE+E E +E E +
Sbjct: 512 PVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGET 571
Query: 1090 SQDVLRCQSSSKRKSKDEEEDEE----SDDADDTPILKPVSLLRKRDVKNSPLEPDTSTP 1145
+ ++ +K + K EE+ EE + D + KP K V SP+E +P
Sbjct: 572 EAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEK--AKSPVPKSPVEEKGKSP 629
Query: 1146 LKKKKGWPKGKSRKPIHWKKRPGRKPGFKLSREIMPVSTQACVIEPIVSIPKAGRKPKIQ 1205
+ K KGKS P + G+ P P + + G+ P
Sbjct: 630 VPKSPVEEKGKSPVPKSPVEEKGKSP------------------VPKSPVEEKGKSP--- 668
Query: 1206 ESEETVEPKEDMPLPEERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSNSPETET 1265
S+ VE K P+P+ EE + +AE + E+ EEE+ E P
Sbjct: 669 VSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAP--------------- 713
Query: 1266 KEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDEDDGHLE 1325
KE +VE++EEKP+ E++++E +E+A AE HLE
Sbjct: 714 KEEKVEKKEEKPKDVPEKKKAES----------PVKEEAVAEVV-----TITKSVKVHLE 758
Query: 1326 STKKKE---LEEQPTREDVKEEPGVQESFLDANMQKSRE-------KIKDKEETELDSEE 1375
K+E L+++ +E E G +E D + SR+ +++ KEE E +++E
Sbjct: 759 KETKEEGKPLQQEKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEVEQETKE 818
Query: 1376 EQP--SHDTSVVSEQMAGSEDDHEEDSHTKEE-LIELKEEEEIPHSELDLETVQAVQSLT 1432
+ + VV+ + S D ++ EE ++ K E+I D T +S+T
Sbjct: 819 KGSGREEEKGVVTNGLDLSPADEKKGGDKSEEKVVVTKTVEKITSEGGDGATKYITKSVT 878
Query: 1433 -QEESSEHEGAYQDCEETLAACQTLQSYT 1460
++ EHE + EE L + + ++ T
Sbjct: 879 VTQKVEEHEETF---EEKLVSTKKVEKVT 904
Score = 68.2 bits (165), Expect = 8e-11
Identities = 64/276 (23%), Positives = 120/276 (43%), Gaps = 45/276 (16%)
Query: 1191 PIVSIPKAGRKPKIQESEETVEPK------EDMPLPEERKEEEE------------MQAE 1232
P ++I +KPK++ + V+ K E+ + +E+ E EE M+ E
Sbjct: 428 PPITISSKIQKPKVEAPKLKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEE 487
Query: 1233 AEEAEEGEEEDAASSEVPAASPADSSNSPETETKEPEVEEEEEKPRVSEEQRQSEEEQQE 1292
+EA E +EE+ + E A+ + E KE E E+EEE+ + EEE++E
Sbjct: 488 KKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQ--------EEEEEE 539
Query: 1293 LEEPEPEEEEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQPTREDVKEEPGVQESFL 1352
E + ++ E+ +E + + + ++++G E+ E + + KEE V+E
Sbjct: 540 DEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEA------EAEGEEAEAKEEKKVEE--- 590
Query: 1353 DANMQKSREKIKDKEETELDSEEEQPSHDTSVVSEQMAGSEDDHEEDSHTKEELIELKEE 1412
E++ KEE D++ E+P S V + S + + S + +E K +
Sbjct: 591 ------KSEEVATKEELVADAKVEKPEKAKSPVPK----SPVEEKGKSPVPKSPVEEKGK 640
Query: 1413 EEIPHSELDLETVQAVQSLTQEESSEHEGAYQDCEE 1448
+P S ++ + V EE + + EE
Sbjct: 641 SPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEE 676
Score = 54.3 bits (129), Expect = 1e-06
Identities = 112/509 (22%), Positives = 188/509 (36%), Gaps = 131/509 (25%)
Query: 777 TPVIVSNSVVSEEEEEEAEEGENEEPQCQEREL--EISVGKSVSHENKEQDSYSVESEKK 834
T + +V +EE++EA E + EEP+ +E E+ + S K+ + E KE++ E E +
Sbjct: 474 TAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQ 533
Query: 835 PEVMAPVSSTRLSKQVLPHDSLPANSQPSRRGRWGRKNRKTQERFGDKDSKLLLEETSSA 894
E G K+ + +E +K+ EE
Sbjct: 534 EE--------------------------EEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQE 567
Query: 895 PQEQYGEC-GEKSEATQEQYTESEEQLVASEEQPSQDGKPDLPKRRLSEGVEPWRGQLKK 953
E E GE++EA +E+ E + + VA++E+ D K + P++ + + K
Sbjct: 568 EGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKA--------KSPVPK 619
Query: 954 SPEALKCRLTEGSERLPRRYSEGDRAVLRGFSESSEEEEEPESPRSSSPPILTKPTLKRK 1013
SP K G +P+ S EE+ +SP SP K K
Sbjct: 620 SPVEEK-----GKSPVPK----------------SPVEEKGKSPVPKSP-----VEEKGK 653
Query: 1014 KPFLHRRRRVRKRKHHNSSVVTETISETTEVLDEPFEDSDSERPMPRLEPTFEIDEEEEE 1073
P + + + S V E + V P E++ S+ + + E ++EEE
Sbjct: 654 SPVPKSPVEEKGKSPVSKSPVEE--KAKSPVPKSPVEEAKSKAEVGKGE------QKEEE 705
Query: 1074 EDENELFPREYFRRLSSQDVLRCQSSSK---RKSKDEEEDEESDDADDTPILKPVSLLRK 1130
E E + P+E + V + + K K K E +E A+ I K V + +
Sbjct: 706 EKEVKEAPKE-------EKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLE 758
Query: 1131 RDVK--NSPLEPDTSTPLKKKKGWPKGKSRKPIHWKKRPGRKPGFKLSREIMPVSTQACV 1188
++ K PL+ + K+K G G + G G K SR
Sbjct: 759 KETKEEGKPLQQEKE---KEKAGGEGGSEEE--------GSDKGAKGSR----------- 796
Query: 1189 IEPIVSIPKAGRKPKIQESEETVEPKEDMPLPEERKEEEEMQAEAEEAEEG-EEEDAASS 1247
KED+ + E + +EE++ E +E G EEE +
Sbjct: 797 -------------------------KEDIAVNGEVEGKEEVEQETKEKGSGREEEKGVVT 831
Query: 1248 EVPAASPADSSNSPETETKEPEVEEEEEK 1276
SPAD + ++ V + EK
Sbjct: 832 NGLDLSPADEKKGGDKSEEKVVVTKTVEK 860
Score = 35.8 bits (81), Expect = 0.43
Identities = 58/275 (21%), Positives = 104/275 (37%), Gaps = 23/275 (8%)
Query: 770 DPECLRWTPVIVSNSVVSEEEEEEAEEGENEEPQCQERELEISVGKSVSHENKEQDSYSV 829
+PE + V + E + EEGE EE + QE E E G + S + +E S
Sbjct: 498 EPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEG-AKSDQAEEGGSEKE 556
Query: 830 ESEKKPEVMAPVSSTRLSKQVLPHDSLPANSQPSRRGRWGRKNRKTQERFGDKDSKLLLE 889
S +K E T + A ++ ++ + T+E D+K+
Sbjct: 557 GSSEKEEGEQEEGETEAEA-----EGEEAEAKEEKKVEEKSEEVATKEEL-VADAKVEKP 610
Query: 890 ETSSAPQEQYGECGEKSEATQEQYTESEEQLVASEEQPSQDGKPDLPKRRLSEGVEPWRG 949
E + +P + + + E + + + + GK +PK S E +
Sbjct: 611 EKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPK---SPVEEKGKS 667
Query: 950 QLKKSPEALKCRLTEGSERLPRRYSEGDRAVLRGFSESSEEEEEPESPRSSSPPILTKPT 1009
+ KSP K + + P ++ V +G + EE+E E+P+ K
Sbjct: 668 PVSKSPVEEKAK--SPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEE------KVE 719
Query: 1010 LKRKKPFLHRRRRVRKRKHHNSSVVTETISETTEV 1044
K +KP + V ++K S V E ++E +
Sbjct: 720 KKEEKP-----KDVPEKKKAESPVKEEAVAEVVTI 749
Score = 32.0 bits (71), Expect = 6.3
Identities = 51/233 (21%), Positives = 86/233 (36%), Gaps = 36/233 (15%)
Query: 1330 KELEEQPTREDVKEEPGVQESFLDANMQKSREKIKDKEETELDSEEEQPSHDTSVVSEQM 1389
K +EE V++E E L A ++ +K++++ + +EE+P
Sbjct: 451 KFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPE---------- 500
Query: 1390 AGSEDDHEEDSHTKEELIELKE-----EEEIPHSELDLETVQAVQSLTQEESSEHEGAYQ 1444
A E+ + S K E+KE EEE E + E A +E SE EG+ +
Sbjct: 501 AEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSE 560
Query: 1445 ----DCEETLAACQTLQSYTQADEDPQM-----------SMVEDCHASEHNSPISSVQSH 1489
+ EE + +A E+ ++ +V D + S V
Sbjct: 561 KEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKS 620
Query: 1490 PSQSVRSVSSPNVPALESGYTQI--SP--EQGSLSAPS--MQNMETSPMMDVP 1536
P + P P E G + + SP E+G P ++ SP+ P
Sbjct: 621 PVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSP 673
>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 [Homo
sapiens]
Length = 540
Score = 86.7 bits (213), Expect = 2e-16
Identities = 105/455 (23%), Positives = 185/455 (40%), Gaps = 41/455 (9%)
Query: 989 EEEEEPESPRSSSPPILTKPTLKRKKPFLHRRRRVRKRKHHNSSVVTETISETTEVLDEP 1048
EE++E + P + +K P V++ + E E E DE
Sbjct: 110 EEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEE---EEGQEEEEEEDEG 166
Query: 1049 FEDSDSERPMPRLEPTFEIDEEEEEEDENELFPREYFRRLSSQDVLRCQSSSKRKSKDEE 1108
+ +E E + E +E E+EE E E + + + K + K EE
Sbjct: 167 AKSDQAEEGGSEKEGSSEKEEGEQEEGETEAE--------AEGEEAEAKEEKKVEEKSEE 218
Query: 1109 EDEESDDADDTPILKPVSLLRKRDVKNSPLEPDTSTPLKKKKGWPKGKSRKPIHWKKRPG 1168
+ + D + KP K V SP+E +P+ K KGKS P + G
Sbjct: 219 VATKEELVADAKVEKPEKA--KSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKG 276
Query: 1169 RKPGFKLSREIMPVSTQACVIEPIVSIPKAGRKPKIQESEETVEPKEDMPLPEERKEEEE 1228
+ P K PV + + + + P + E + K ++ E+++EEE+
Sbjct: 277 KSPVPK-----SPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEK 331
Query: 1229 MQAEAEEAEEGEEEDAASSEVPAASPADSSNSPE------TETKEPEVE-EEEEKPRVSE 1281
EA + E+ E+++ +VP A+S E T TK +V E+E K
Sbjct: 332 EVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKP 391
Query: 1282 EQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQPTRE-- 1339
Q++ E+E+ E EE D A+ ++ +D + E +G KE EQ T+E
Sbjct: 392 LQQEKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEG-------KEEVEQETKEKG 444
Query: 1340 -DVKEEPGVQESFLD---ANMQKSREKIKDK---EETELDSEEEQPSHDTSVVSEQMAGS 1392
+EE GV + LD A+ +K +K ++K +T E T +++ + +
Sbjct: 445 SGREEEKGVVTNGLDLSPADEKKGGDKSEEKVVVTKTVEKITSEGGDGATKYITKSVTVT 504
Query: 1393 EDDHEEDSHTKEELIELKEEEEIPHSELDLETVQA 1427
+ E + +E+L+ K+ E++ + E Q+
Sbjct: 505 QKVEEHEETFEEKLVSTKKVEKVTSHAIVKEVTQS 539
Score = 81.3 bits (199), Expect = 9e-15
Identities = 115/509 (22%), Positives = 195/509 (38%), Gaps = 88/509 (17%)
Query: 984 FSESSEEEEEPESPRSSSPPILTKPTLKRKKPFLHRRRRVRKRKHHNSSVVTETISETTE 1043
F E EE + E +S LT T + ++ + K E ++
Sbjct: 76 FVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKS 135
Query: 1044 VLDEPFEDSDSERPMPRLEPTFEIDEEEEE--------------EDENELFPREYFRRLS 1089
+ + E E E +EEE+E E +E E +
Sbjct: 136 PVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGET 195
Query: 1090 SQDVLRCQSSSKRKSKDEEEDEE----SDDADDTPILKPVSLLRKRDVKNSPLEPDTSTP 1145
+ ++ +K + K EE+ EE + D + KP K V SP+E +P
Sbjct: 196 EAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEK--AKSPVPKSPVEEKGKSP 253
Query: 1146 LKKKKGWPKGKSRKPIHWKKRPGRKPGFKLSREIMPVSTQACVIEPIVSIPKAGRKPKIQ 1205
+ K KGKS P + G+ P P + + G+ P
Sbjct: 254 VPKSPVEEKGKSPVPKSPVEEKGKSP------------------VPKSPVEEKGKSP--- 292
Query: 1206 ESEETVEPKEDMPLPEERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSNSPETET 1265
S+ VE K P+P+ EE + +AE + E+ EEE+ E P
Sbjct: 293 VSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAP--------------- 337
Query: 1266 KEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDEDDGHLE 1325
KE +VE++EEKP+ E++++E +E+A AE HLE
Sbjct: 338 KEEKVEKKEEKPKDVPEKKKAES----------PVKEEAVAEVV-----TITKSVKVHLE 382
Query: 1326 STKKKE---LEEQPTREDVKEEPGVQESFLDANMQKSRE-------KIKDKEETELDSEE 1375
K+E L+++ +E E G +E D + SR+ +++ KEE E +++E
Sbjct: 383 KETKEEGKPLQQEKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEVEQETKE 442
Query: 1376 EQP--SHDTSVVSEQMAGSEDDHEEDSHTKEE-LIELKEEEEIPHSELDLETVQAVQSLT 1432
+ + VV+ + S D ++ EE ++ K E+I D T +S+T
Sbjct: 443 KGSGREEEKGVVTNGLDLSPADEKKGGDKSEEKVVVTKTVEKITSEGGDGATKYITKSVT 502
Query: 1433 -QEESSEHEGAYQDCEETLAACQTLQSYT 1460
++ EHE + EE L + + ++ T
Sbjct: 503 VTQKVEEHEETF---EEKLVSTKKVEKVT 528
Score = 68.2 bits (165), Expect = 8e-11
Identities = 64/276 (23%), Positives = 120/276 (43%), Gaps = 45/276 (16%)
Query: 1191 PIVSIPKAGRKPKIQESEETVEPK------EDMPLPEERKEEEE------------MQAE 1232
P ++I +KPK++ + V+ K E+ + +E+ E EE M+ E
Sbjct: 52 PPITISSKIQKPKVEAPKLKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEE 111
Query: 1233 AEEAEEGEEEDAASSEVPAASPADSSNSPETETKEPEVEEEEEKPRVSEEQRQSEEEQQE 1292
+EA E +EE+ + E A+ + E KE E E+EEE+ + EEE++E
Sbjct: 112 KKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQ--------EEEEEE 163
Query: 1293 LEEPEPEEEEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQPTREDVKEEPGVQESFL 1352
E + ++ E+ +E + + + ++++G E+ E + + KEE V+E
Sbjct: 164 DEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEA------EAEGEEAEAKEEKKVEE--- 214
Query: 1353 DANMQKSREKIKDKEETELDSEEEQPSHDTSVVSEQMAGSEDDHEEDSHTKEELIELKEE 1412
E++ KEE D++ E+P S V + S + + S + +E K +
Sbjct: 215 ------KSEEVATKEELVADAKVEKPEKAKSPVPK----SPVEEKGKSPVPKSPVEEKGK 264
Query: 1413 EEIPHSELDLETVQAVQSLTQEESSEHEGAYQDCEE 1448
+P S ++ + V EE + + EE
Sbjct: 265 SPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEE 300
Score = 54.3 bits (129), Expect = 1e-06
Identities = 112/509 (22%), Positives = 188/509 (36%), Gaps = 131/509 (25%)
Query: 777 TPVIVSNSVVSEEEEEEAEEGENEEPQCQEREL--EISVGKSVSHENKEQDSYSVESEKK 834
T + +V +EE++EA E + EEP+ +E E+ + S K+ + E KE++ E E +
Sbjct: 98 TAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQ 157
Query: 835 PEVMAPVSSTRLSKQVLPHDSLPANSQPSRRGRWGRKNRKTQERFGDKDSKLLLEETSSA 894
E G K+ + +E +K+ EE
Sbjct: 158 EE--------------------------EEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQE 191
Query: 895 PQEQYGEC-GEKSEATQEQYTESEEQLVASEEQPSQDGKPDLPKRRLSEGVEPWRGQLKK 953
E E GE++EA +E+ E + + VA++E+ D K + P++ + + K
Sbjct: 192 EGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKA--------KSPVPK 243
Query: 954 SPEALKCRLTEGSERLPRRYSEGDRAVLRGFSESSEEEEEPESPRSSSPPILTKPTLKRK 1013
SP K G +P+ S EE+ +SP SP K K
Sbjct: 244 SPVEEK-----GKSPVPK----------------SPVEEKGKSPVPKSP-----VEEKGK 277
Query: 1014 KPFLHRRRRVRKRKHHNSSVVTETISETTEVLDEPFEDSDSERPMPRLEPTFEIDEEEEE 1073
P + + + S V E + V P E++ S+ + + E ++EEE
Sbjct: 278 SPVPKSPVEEKGKSPVSKSPVEE--KAKSPVPKSPVEEAKSKAEVGKGE------QKEEE 329
Query: 1074 EDENELFPREYFRRLSSQDVLRCQSSSK---RKSKDEEEDEESDDADDTPILKPVSLLRK 1130
E E + P+E + V + + K K K E +E A+ I K V + +
Sbjct: 330 EKEVKEAPKE-------EKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLE 382
Query: 1131 RDVK--NSPLEPDTSTPLKKKKGWPKGKSRKPIHWKKRPGRKPGFKLSREIMPVSTQACV 1188
++ K PL+ + K+K G G + G G K SR
Sbjct: 383 KETKEEGKPLQQEKE---KEKAGGEGGSEEE--------GSDKGAKGSR----------- 420
Query: 1189 IEPIVSIPKAGRKPKIQESEETVEPKEDMPLPEERKEEEEMQAEAEEAEEG-EEEDAASS 1247
KED+ + E + +EE++ E +E G EEE +
Sbjct: 421 -------------------------KEDIAVNGEVEGKEEVEQETKEKGSGREEEKGVVT 455
Query: 1248 EVPAASPADSSNSPETETKEPEVEEEEEK 1276
SPAD + ++ V + EK
Sbjct: 456 NGLDLSPADEKKGGDKSEEKVVVTKTVEK 484
Score = 35.8 bits (81), Expect = 0.43
Identities = 58/275 (21%), Positives = 104/275 (37%), Gaps = 23/275 (8%)
Query: 770 DPECLRWTPVIVSNSVVSEEEEEEAEEGENEEPQCQERELEISVGKSVSHENKEQDSYSV 829
+PE + V + E + EEGE EE + QE E E G + S + +E S
Sbjct: 122 EPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEG-AKSDQAEEGGSEKE 180
Query: 830 ESEKKPEVMAPVSSTRLSKQVLPHDSLPANSQPSRRGRWGRKNRKTQERFGDKDSKLLLE 889
S +K E T + A ++ ++ + T+E D+K+
Sbjct: 181 GSSEKEEGEQEEGETEAEA-----EGEEAEAKEEKKVEEKSEEVATKEEL-VADAKVEKP 234
Query: 890 ETSSAPQEQYGECGEKSEATQEQYTESEEQLVASEEQPSQDGKPDLPKRRLSEGVEPWRG 949
E + +P + + + E + + + + GK +PK S E +
Sbjct: 235 EKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPK---SPVEEKGKS 291
Query: 950 QLKKSPEALKCRLTEGSERLPRRYSEGDRAVLRGFSESSEEEEEPESPRSSSPPILTKPT 1009
+ KSP K + + P ++ V +G + EE+E E+P+ K
Sbjct: 292 PVSKSPVEEKAK--SPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEE------KVE 343
Query: 1010 LKRKKPFLHRRRRVRKRKHHNSSVVTETISETTEV 1044
K +KP + V ++K S V E ++E +
Sbjct: 344 KKEEKP-----KDVPEKKKAESPVKEEAVAEVVTI 373
Score = 32.0 bits (71), Expect = 6.3
Identities = 51/233 (21%), Positives = 86/233 (36%), Gaps = 36/233 (15%)
Query: 1330 KELEEQPTREDVKEEPGVQESFLDANMQKSREKIKDKEETELDSEEEQPSHDTSVVSEQM 1389
K +EE V++E E L A ++ +K++++ + +EE+P
Sbjct: 75 KFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPE---------- 124
Query: 1390 AGSEDDHEEDSHTKEELIELKE-----EEEIPHSELDLETVQAVQSLTQEESSEHEGAYQ 1444
A E+ + S K E+KE EEE E + E A +E SE EG+ +
Sbjct: 125 AEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSE 184
Query: 1445 ----DCEETLAACQTLQSYTQADEDPQM-----------SMVEDCHASEHNSPISSVQSH 1489
+ EE + +A E+ ++ +V D + S V
Sbjct: 185 KEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKS 244
Query: 1490 PSQSVRSVSSPNVPALESGYTQI--SP--EQGSLSAPS--MQNMETSPMMDVP 1536
P + P P E G + + SP E+G P ++ SP+ P
Sbjct: 245 PVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSP 297
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 85.5 bits (210), Expect = 5e-16
Identities = 157/734 (21%), Positives = 286/734 (38%), Gaps = 112/734 (15%)
Query: 791 EEEAEEGENEEPQCQERELEISVGKSVSHENKEQDSYSVESEKKPEVMAPVSSTRLSKQV 850
+E+ E+ E + Q +E E + + E + ++ ++E+K E S R +
Sbjct: 733 QEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLRE 792
Query: 851 LPHDSLPANSQPSRRGRW-----GRKNRKTQERFGDKDSKLLLEETSSAPQEQYGECGEK 905
L A + R R+ ++ R+ Q R +K+ + L EE +E+ + E+
Sbjct: 793 QRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEE 852
Query: 906 SEATQEQYTESEEQLVASEEQPSQDGKPDLPKRRLSEGVEP-WRGQLKKSPEALKCRLTE 964
+ QE Q +++ + + +RR + +P + QL+K + L+ E
Sbjct: 853 EDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQ----E 908
Query: 965 GSERLPRRYSEGDRAVLRGFSESSEEEEEPESPRSSSPPILTKPTLKRKKPFLHRRRRVR 1024
E L R E R E + E E + +L + +R+K RRR+ R
Sbjct: 909 EEEELQREEREKRRR-----QEQERQYREEEQLQQEEEQLLRE---EREK----RRRQER 956
Query: 1025 KRKHHNSSVVTETISETTEVLDEPFEDSDSERPMPRLEPTFEIDEEEEEEDENELFPREY 1084
+R++ + + E + +EP + ER E EEE +++E +L E
Sbjct: 957 ERQYRKDKKLQQ--KEEQLLGEEPEKRRRQEREKKYRE------EEELQQEEEQLLREER 1008
Query: 1085 FRRLSSQDVLRCQSSSKRKSKDEEEDEESDDADDTPILKPVSLLR----KRDVKNSPLEP 1140
+R R + + + KDE + EE LLR KR ++ +
Sbjct: 1009 EKRR------RQEWERQYRKKDELQQEEEQ------------LLREEREKRRLQERERQY 1050
Query: 1141 DTSTPLKKKKGWPKGKSRKPIHWKKRPGRKPGFKLSREIMPVSTQACVIEPIVSIPKAGR 1200
L++++ G+ R+ ++R + ++ E+ Q EP K R
Sbjct: 1051 REEEELQQEEEQLLGEERET---RRRQELERQYRKEEELQQEEEQLLREEP----EKRRR 1103
Query: 1201 KPKIQE--SEETVEPKEDMPLPEER------------KEEEEMQAEAEEAEEGEEEDAAS 1246
+ + ++ EE ++ +E+ L EER +EEEE+Q E E+ E E
Sbjct: 1104 QERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRR 1163
Query: 1247 SEVPAASPADSSNSPETET------------KEPEVEEEEEKPRVSEEQRQSEEEQQ-EL 1293
E+ + E E +E + EEEE R +QR +E+Q+ +L
Sbjct: 1164 QELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDL 1223
Query: 1294 E---EPEP--------------EEEEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQP 1336
+ EPE E E+ E +Q D + + L ++++ E++
Sbjct: 1224 KWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQER 1283
Query: 1337 TREDVKEEPGVQESFLDANMQK--SREKIKDKEETELDSEEEQPSHDTSVVSEQMAGSE- 1393
R ++ +E L+ QK R K +EE +L EE + + E
Sbjct: 1284 RRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQ 1343
Query: 1394 --DDHEEDSHTKEELIELKEEEEIPHSELDLETVQAVQSLTQEESSEHEGAYQDCEETLA 1451
+ EE ++E EEE+ H E + ++ Q L ++ E E + EE
Sbjct: 1344 LLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQ---ERERKFLK-EEQQL 1399
Query: 1452 ACQTLQSYTQADED 1465
CQ + + D D
Sbjct: 1400 RCQEREQQLRQDRD 1413
Score = 83.6 bits (205), Expect = 2e-15
Identities = 130/700 (18%), Positives = 263/700 (37%), Gaps = 68/700 (9%)
Query: 790 EEEEAEEGENEEPQC-----QERELEISVGKSVSHENKEQDSYSVESEKKPEVMAPVSST 844
E++E E + E + QE E + + E +EQ + E++ E
Sbjct: 323 EQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQ 382
Query: 845 RLSKQVLPHDSLPANSQPSRRGRWGRKNRKTQERFGDKDSKLLLEETSSAPQEQYGECGE 904
+Q L + Q RR + R+ ++ + + + L E EQ E
Sbjct: 383 LRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQER 442
Query: 905 KSEATQEQYTESEEQLVASEE---QPSQDGKPDLPKRRLSEGVEPWRGQLKKSPEALKCR 961
+ + + + E + L EE + K L + + E E W LK E + +
Sbjct: 443 REQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERW---LKLEEEERREQ 499
Query: 962 LTEGSERLPRRYSEGDRAVLRGFSESSEEEEEPESPRSSSPPILTKPTLKRKKPFLHRRR 1021
++L R E L+ +EEEE R S L + +R++ L R
Sbjct: 500 QERREQQLRREQEERREQRLK-----RQEEEERLQQRLRSEQQLRREQEERREQLLKREE 554
Query: 1022 RVRKRKHHNSSVVTETISETTEVLDEPFEDSDSERPMPRLEPTFEIDEEEEEEDENELFP 1081
R + + + E + + ER RL + E+EE +
Sbjct: 555 EKRLEQERRE----QRLKREQEERRDQLLKREEERRQQRL-------KREQEERLEQRLK 603
Query: 1082 REYFRRLSSQDVLRCQSSSKRKSKDEE------EDEESDDADDTPILKPVSLLRKRDVKN 1135
RE RL ++ R + KR+ +EE + EE ++ + + R++ +K
Sbjct: 604 REEVERLEQEE--RREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKR 661
Query: 1136 SPLEPDTSTPLKKKKGWPKGKSRKPIHWKKRPGRKPGFKLSREIMPVSTQACVIE-PIVS 1194
E LK++ + + +++ + ++ + + ++A + + S
Sbjct: 662 EEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYS 721
Query: 1195 IPK--AGRKPKIQESEETVEPKEDMPLPEERKEEEEMQAEAE------EAEEGEEEDAAS 1246
P+ G++ + ++ E+ + ++ EE + + Q E + + + E+ +
Sbjct: 722 RPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGR 781
Query: 1247 SEVPAASPADSSNSPETETKEPE------VEEEEEKPRVSEEQRQSEEEQQELEEPEPEE 1300
+ A P + +E + + EEEEK + ++R+ E+E Q LEE E +
Sbjct: 782 QRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQ 841
Query: 1301 EEDAAAETAQNDDHDADDEDDGHLESTKKK-------ELEEQPTREDVKEEPGVQESFLD 1353
+ A + + +D +D++ + ++ E E + R + +P +QE
Sbjct: 842 RRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQL-- 899
Query: 1354 ANMQKSREKIKDKEETELDSEEEQPSHDTSVVSEQMAGSEDDHEEDSHTKEELIELKEEE 1413
+ +++ +EE EL EE + + + EE+ +EE + + +E
Sbjct: 900 ----RKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQE 955
Query: 1414 EIPHSELDLETVQAVQSLTQEE-----SSEHEGAYQDCEE 1448
D + Q + L EE E E Y++ EE
Sbjct: 956 RERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEE 995
Score = 83.6 bits (205), Expect = 2e-15
Identities = 139/707 (19%), Positives = 275/707 (38%), Gaps = 101/707 (14%)
Query: 789 EEEEEAEEGENEEPQCQERELEISVGKSVSHENKEQDSYSVESEKKPEVMAPVSSTRL-- 846
EEEE + + + +++ ++ EN +D+ ++ E + ++L
Sbjct: 1201 EEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRD 1260
Query: 847 --SKQVLPH--DSLPANSQPSRRGRWGRKNR----------------KTQERFGDKDSKL 886
S+Q L H + R RW +++R K ++R ++ +L
Sbjct: 1261 RQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQL 1320
Query: 887 LLEETSSAPQEQYGECGEKSEATQEQYTESEEQLVASEEQPSQDGKPDLPK----RRLSE 942
L EE + Q E K ++ E EEQ + +E+ + + +L R+ E
Sbjct: 1321 LREEREEKRRRQ--ETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLE 1378
Query: 943 GVEPWRGQLK-----KSPEALKCRLTEGSERLPR--RYSEGDRAVLRGFSESSEEEEEPE 995
+ R Q + K + L+C+ E R R ++ E ++ + R + EEE +
Sbjct: 1379 EEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQ 1438
Query: 996 SPRSSSPPILTKPTLKRKKPFLHRRRRVRKRKHHNSSVVTETISETTEVL------DEPF 1049
R +R++ FL +++R+ +H + + E E D F
Sbjct: 1439 VRRQ-----------ERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKF 1487
Query: 1050 EDSDSERPMPRLEPTFEIDEEEEEEDENELFPREYFRRLSSQDVLRCQSSSKRKSKDEEE 1109
+ + + + F E +E E + E ++L Q R +++ + +E
Sbjct: 1488 LEEEQQLRRQERDRKFREQELRSQEPERKFLEEE--QQLHRQQRQRKFLQEEQQLRRQER 1545
Query: 1110 DEESDDADDTPILKPVSLLRKRDVKN-SPLEPDTSTPLKKKKGWPKGKSRKPIHWKKRPG 1168
++ D + L ++R+ + S E D L+++K + + RK + +++
Sbjct: 1546 GQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLR 1605
Query: 1169 RKPGFKLSREIMPVSTQACVIEPIVSIPKAGRKPKIQESEETVEPKEDMPLPEERKE--- 1225
R+ G + R+ R K +E E+ ++ +E+ L + ++
Sbjct: 1606 RQEGQQQLRQ--------------------ERDRKFREDEQLLQEREEQQLHRQERDRKF 1645
Query: 1226 -EEEMQAEAEEAEEG--EEEDAASSEVPAASPADSSNSPETETKEPEVEEEEEKPRVSEE 1282
EEE Q +E E+ + D E + ++ + EEE++ R E
Sbjct: 1646 LEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQER 1705
Query: 1283 QRQSEEEQQELEEPEPE----EEEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQPTR 1338
+R+ +E+Q+L E E EEE ET Q + E + E EEQ R
Sbjct: 1706 ERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLR 1765
Query: 1339 ED-----VKEEPGVQESFLDANMQKSREKIKDKEETELDSEEEQPSHDTSVVSEQMAGSE 1393
+EE +++ + ++ K +EE +L E E+ +Q+ +
Sbjct: 1766 RQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREE---------QQLRPQQ 1816
Query: 1394 DDHEEDSHTKEELIELKEEEEIPHSELDLETVQAVQSLTQEESSEHE 1440
D + +EE ++L+E+E+ E D + Q TQE+S E
Sbjct: 1817 RDGK--YRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREE 1861
Score = 81.3 bits (199), Expect = 9e-15
Identities = 160/780 (20%), Positives = 298/780 (38%), Gaps = 76/780 (9%)
Query: 748 RREKLI--QDHMAKLQLNLRPVDVDPECLRWTPVIVSNSVVSEEEEEEAEEGENEEPQCQ 805
RRE+ + Q+ +LQ LR + LR ++ EEE+ E+ E+ +
Sbjct: 514 RREQRLKRQEEEERLQQRLR----SEQQLRREQEERREQLLKREEEKRLEQERREQRLKR 569
Query: 806 ERELEISVGKSVSHENKEQDSYSVESEKKPEVMAPVSSTRLSKQVLPHDSLPANSQPSRR 865
E+E E ++Q + E+ + + RL ++ L R
Sbjct: 570 EQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEER 629
Query: 866 GRWGRKNRKTQERFGDKDSKLLLEETSSAPQEQYGECGEKSEATQEQYTESEEQLVASEE 925
+ K+ + +ER + + E + + E + +E E EQ +A EE
Sbjct: 630 RQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEE 689
Query: 926 QPSQDGKPDLPKRRLSEGVEPWRGQLKKSPEALKCRLTEGSERLP--RRYSEGDRAVLRG 983
Q + + R+ + W+ QL+ +A + ++ + RR E + R
Sbjct: 690 Q-------EQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRR 742
Query: 984 FSESSEEEEE--------PESPRSSSPPILTKPTLKRKKPFLHRRRRVRKRKHHNSSVVT 1035
SE +EEE E R + + +R + L R +R+++
Sbjct: 743 ESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEE 802
Query: 1036 ETISETTEVLDEPFEDSDSERPMPRLEPTFEIDEEEEEEDENELFPREYFRRLSSQDVLR 1095
E + P E+ +R R E E+ EEEE +L RE ++L ++
Sbjct: 803 RQQREQRFL---PEEEEKEQRRRQRREREKELQFLEEEE---QLQRRERAQQLQEEEDGL 856
Query: 1096 CQSSSKRKSKDEEED--------EESDDADDTPILKPVSLLRKRDVKNSPLEPDTSTPLK 1147
+ +R+S+++ D EE T KP L+++ K L + L+
Sbjct: 857 QEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPA--LQEQLRKEQQLLQEEEEELQ 914
Query: 1148 KKKGWPKGKSRKPIHWKKRPGRKPGFKLSREIMPVSTQACVIEPIVSIPKAGRKPK-IQE 1206
+++ + + + +++ +L +E + + + RK K +Q+
Sbjct: 915 REEREKRRRQEQERQYREEE------QLQQEEEQLLREEREKRRRQERERQYRKDKKLQQ 968
Query: 1207 SEETV---EPKEDMPLPEERK--EEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSNSP 1261
EE + EP++ E+K EEEE+Q E E+ E E E
Sbjct: 969 KEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQ 1028
Query: 1262 ETETKEPEVEEEEEKPRVSEEQRQSEEE---QQELEEPEPEEEEDAAAETAQND---DHD 1315
E +E + EE EK R+ E +RQ EE QQE E+ EE E + + + +
Sbjct: 1029 E---EEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEE 1085
Query: 1316 ADDEDDGHLESTKKKELEEQPTREDVKEEPGVQESFLDANMQKSREKIK----------- 1364
E++ L +K ++ R+ +EE QE + +++ REK +
Sbjct: 1086 LQQEEEQLLREEPEKRRRQERERQCREEEELQQEE--EQLLREEREKRRRQELERQYREE 1143
Query: 1365 ---DKEETELDSEEEQPSHDTSVVSEQMAGSEDDHEEDSHTKEELIELKEEEEIPHSELD 1421
+EE +L EE + + + E EE+ +EE + ++E E + E +
Sbjct: 1144 EEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEE 1203
Query: 1422 LETVQAVQSLTQEESSEHEGAYQDCEETLAACQTLQSYTQADEDPQMSMVEDCHASEHNS 1481
Q + ++E + +Q E A + + Y + E+ Q +ED + S
Sbjct: 1204 ELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQS 1263
Score = 80.5 bits (197), Expect = 2e-14
Identities = 140/707 (19%), Positives = 267/707 (37%), Gaps = 49/707 (6%)
Query: 792 EEAEEGENEEPQCQERELEISVGKSVSHENKEQDSYSVESEKKPEVMAPVSSTRLSKQVL 851
+ E E EE + +E +L+ G HE +E E ++ E++ R KQ
Sbjct: 176 QRQEWQEREERRAEEEQLQSCKG----HETEEFPDE--EQLRRRELLELRRKGREEKQQQ 229
Query: 852 PHDSLPANSQPSRRGRWGRKN-------RKTQERFGDKDSKLLLEETSSAPQEQYGECGE 904
+ Q W ++ K QE + +L EE E+ E
Sbjct: 230 RRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRE 289
Query: 905 KSEATQEQYTESEEQLVASEEQPSQDGKPDLPKRRLSEGVEPWRGQLKKSPEALKCRLTE 964
+ E Q+Q EQ + +++ ++ + +RR E E Q ++ + L+ E
Sbjct: 290 RQEEEQQQQRLRREQQLRRKQE--EERREQQEERR--EQQERREQQEERREQQLRREQEE 345
Query: 965 GSERLPRRYSEGDRAVLRGFSESSEEEEEPESPRSSSPPILTKPTLKRKKPFLHRRRRVR 1024
E+ RR E +R + E EE E + R L + R++ L R +++R
Sbjct: 346 RREQQLRREQEEERREQQLRREQEEERREQQLRREQQ---LRREQQLRREQQLRREQQLR 402
Query: 1025 K----RKHHNSSVVTETISETTEVLDEPFEDSDSERPMPRLEPTFEIDEEEEEE---DEN 1077
+ R+ + E ++ E + + R E + ++EE + E
Sbjct: 403 REQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREE 462
Query: 1078 ELFPREYFRRLSSQDVLRCQSSSKRK---SKDEEEDEESDDADDTPILKPVSLLRKRDVK 1134
E E RR Q + R Q +R+ +EEE E + + + + R++ +K
Sbjct: 463 ETERHEQERR--KQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLK 520
Query: 1135 NSPLEPDTSTPLKKKKGWPKGKSRKPIHWKKRPGRKPGFKLSREIMPVSTQACVIEPIVS 1194
E L+ ++ + + + KR K + RE Q + ++
Sbjct: 521 RQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLK 580
Query: 1195 IPKAGRKPKIQ-ESEETVEPKEDMPLPE--ERKEEEEMQAEAEEAEEGEEEDAASSEVPA 1251
+ R+ +++ E EE +E + E E++E E + + EE EE + SE
Sbjct: 581 REEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQE 640
Query: 1252 ASPADSSNSPETETKEPEVEEEEEKPRVSEEQRQSEEE---QQELEEPEPEEEEDAAAET 1308
+ E +E ++ EEE+ R+ + ++ EE +QEL E E E+ +
Sbjct: 641 ERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSR 700
Query: 1309 AQNDDHDADDEDDGHLES--TKKKELEEQPTREDVKEEPGVQESFLDANMQKSREKIKDK 1366
+ E D ++ ++ E Q R++ +E+ +ES L ++ + + +
Sbjct: 701 IPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQE 760
Query: 1367 EETELDSEEEQPSHDTSVVSEQMAGSEDD---------HEEDSHTKEELIELKEEEEIPH 1417
EE D + + + S Q + E+ +E+ +EEE+
Sbjct: 761 EEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQR 820
Query: 1418 SELDLETVQAVQSLTQEESSEHEGAYQDCEETLAACQTLQSYTQADE 1464
E + +Q L +EE + Q +E Q Q ++ E
Sbjct: 821 RRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQE 867
Score = 76.3 bits (186), Expect = 3e-13
Identities = 123/666 (18%), Positives = 261/666 (39%), Gaps = 54/666 (8%)
Query: 789 EEEEEAEEGENEEPQCQERELEISVGKSVSHENKEQDSYSVESEKKPEVMAPVSSTRLSK 848
++ + E+ EP+ +R+LE G+ + +EQ+ E E++ E + +
Sbjct: 111 QDRRQEEDQRRFEPR--DRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQR 168
Query: 849 --QVLPHDSLPANSQPSRRGRWGR----KNRKTQERFGDKDS---KLLLEETSSAPQEQY 899
+ L + RR + K +T+E F D++ + LLE +E+
Sbjct: 169 RDEELWRQRQEWQEREERRAEEEQLQSCKGHETEE-FPDEEQLRRRELLELRRKGREEKQ 227
Query: 900 GECGEKSEATQEQYTESE----EQLVASEEQPSQDGKPDLPKRRLSEGVEPWRG------ 949
+ E+ + ++ E E E ++ EE+ Q+ +P +R L E E R
Sbjct: 228 QQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQ-RQRELQEEEEQLRKLERQEL 286
Query: 950 QLKKSPEALKCRLTEGSERLPRRYSEGDRAVLRGFSESSEEEEEPESPRSSSPPILTKPT 1009
+ ++ E + + ++L R+ E R E E E+ E R L +
Sbjct: 287 RRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQ---LRREQ 343
Query: 1010 LKRKKPFLHRRRRVRKRKHHNSSVVTETISETTEVLDEPFEDSDSERPMPRLEPTFEIDE 1069
+R++ L R + +R+ E E ++ R +L ++
Sbjct: 344 EERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRR 403
Query: 1070 EEEEEDENELFPREYFRRLSSQDVLRCQSSSKRKSKDEEEDEES----DDADDTPILKPV 1125
E++ E +L + RR Q + R Q + + K E+E E + + LK
Sbjct: 404 EQQLRREQQLRREQQLRR--EQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKRE 461
Query: 1126 SLLRKRDVKNSPLEPDTSTPLKKKKGWPK---GKSRKPIHWKKRPGRKPGFKLSREIMPV 1182
+ + + + ++++ W K + R+ +++ R+ + + +
Sbjct: 462 EETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKR 521
Query: 1183 STQACVIEPIVSIPKAGRKPKIQESEETVEPKEDMPLPEERKEEEEMQAEAEEAEE--GE 1240
+ ++ + + R+ + + E+ ++ +E+ L +ER+E+ + + E ++
Sbjct: 522 QEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKR 581
Query: 1241 EEDAASSEVPAASPADSSNSPETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEE 1300
EE+ + + E E +EE + R+ E+ + E QQ L+ E EE
Sbjct: 582 EEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEE 641
Query: 1301 EEDAAAETAQNDDHD---ADDEDDGHLESTKKKELEEQPTREDVKEEPGVQESFLDANMQ 1357
Q + + +E++ LE K+E EE+ +++ EE +
Sbjct: 642 RRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEE----------EQE 691
Query: 1358 KSREKIKD---KEETELDSEEEQPSHDTSVVSEQMAGSEDDHEEDSHTKEELIELK-EEE 1413
++RE+IK K + +L+SE + + G E++ + EL+ +EE
Sbjct: 692 QARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEE 751
Query: 1414 EIPHSE 1419
E H +
Sbjct: 752 ERAHRQ 757
Score = 73.9 bits (180), Expect = 1e-12
Identities = 98/433 (22%), Positives = 170/433 (39%), Gaps = 47/433 (10%)
Query: 1050 EDSDSERPMPRLEPTFEIDEEEEEEDENE-LFPREYFRRLSSQDVLRCQSSSKRKSKDEE 1108
E+ R R E E+ E EE+ ++ E L R+ RR R + + + + EE
Sbjct: 131 EEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEE 190
Query: 1109 EDEESDDADDTPILKPVSLLRKRDVKNSPLEPDTSTPLKKKKGWPKGKSRKPIHWKKRPG 1168
E +S +T LR+R++ L+ ++ KG+ K ++R
Sbjct: 191 EQLQSCKGHETEEFPDEEQLRRREL------------LELRR---KGREEKQQQRRERQD 235
Query: 1169 RKPGFKLSREIMPVSTQACVIEPIVSIPKAGRKPKIQESEETVEPKEDMPLPEERKEEEE 1228
R + +E T E + + R+ ++QE EE + E L ER+EEE+
Sbjct: 236 RVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQ 295
Query: 1229 MQ--AEAEEAEEGEEEDAASSEVPAASPADSSNSPETETKEPEVEEEEEKPRVSEEQRQS 1286
Q E+ ++E+ + + E +E ++ E+E+ R + +R+
Sbjct: 296 QQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQ 355
Query: 1287 EEEQQE----LEEPEPEEEEDAAAETAQNDDHDADDEDDGHLESTKKKE----------L 1332
EEE++E E+ E E+ E + E E ++E
Sbjct: 356 EEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRR 415
Query: 1333 EEQPTREDVKEEPGVQESFLDANMQKSREKIKDKEETE----LDSEEEQPSHDTSVVSEQ 1388
E+Q RE +E + Q+ RE+ +E+ E L EEE H+ +Q
Sbjct: 416 EQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQ 475
Query: 1389 MAGSEDDHEEDSHTKEELIELKEEEEIPHSELDLETVQAVQSLTQEESSEHEGAYQDCEE 1448
+ +++ + K E E +E++E +L E QEE E Q+ EE
Sbjct: 476 LKRDQEEERRERWLKLEEEERREQQERREQQLRRE---------QEERREQRLKRQEEEE 526
Query: 1449 TLAACQTLQSYTQ 1461
L Q L+S Q
Sbjct: 527 RLQ--QRLRSEQQ 537
Score = 72.8 bits (177), Expect = 3e-12
Identities = 126/660 (19%), Positives = 262/660 (39%), Gaps = 85/660 (12%)
Query: 790 EEEEAEEGENEEPQCQERELEISVGKSVSHENKEQDSYSVESEKKPEVMAPVSSTRLSKQ 849
EEE+ E E +E + ++R+ + K + E +E+ E+++K R +Q
Sbjct: 1295 EEEQLEREEQKEAKRRDRKSQEE--KQLLREEREEKRRRQETDRK---------FREEEQ 1343
Query: 850 VLPHDSLPANSQPSRRGRWGRKNRKTQERFGDKDSKLLLEETSSAPQEQYGECGEKSEAT 909
+L QP RR RK R+ + R ++ K L EE QE+ E E
Sbjct: 1344 LLQE----REEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQER--ERKFLKEEQ 1397
Query: 910 QEQYTESEEQLVASEEQPSQDGKPDLPKRRLSEGVEPWRGQLKKSPEALKCRLTEGSERL 969
Q + E E+QL ++ ++ + L ++ Q+++ K E R
Sbjct: 1398 QLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQ 1457
Query: 970 PRRYSEGDRAVLRGFSESSEEEEEPESPRSSSPPILTKPTLKRKKPFLHRRRRVRKRKHH 1029
R R + +E EE + R +R + FL +++R+++
Sbjct: 1458 ERHRK------FREEEQLLQEREEQQLHRQ-----------ERDRKFLEEEQQLRRQERD 1500
Query: 1030 NSSVVTETISETTE--VLDEPFEDSDSERPMPRLEPTFEIDEEEEEEDENELFPREYFRR 1087
E S+ E L+E + +R L+ ++ +E + + + R+
Sbjct: 1501 RKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQ----DRDRK 1556
Query: 1088 LSSQDVLRCQSSSKRKSKDE-------EEDEESDDADDTPILKPVSLLRKRDVKNSPLEP 1140
++ LR + ++ S+ E EE + + ++ LR+++ + L
Sbjct: 1557 FREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQ-LRQ 1615
Query: 1141 DTSTPLKKKKGWPKGKSRKPIHWKKRPGRKPGFKLSREIMPVSTQACVIEPIVSIPKAGR 1200
+ ++ + + + + +H ++R R+ + Q E + + R
Sbjct: 1616 ERDRKFREDEQLLQEREEQQLHRQER---------DRKFLEEEPQLRRQEREQQL-RHDR 1665
Query: 1201 KPKIQESEETVEPKEDMPLPEERKE----EEEMQAEAEEAEEG---EEEDAASSEVPAAS 1253
K +E E+ ++ E+ L + ++ EEE Q +E E EE+ E+
Sbjct: 1666 DRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKF 1725
Query: 1254 PADSSNSPETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDD 1313
+ ETE ++ +E K + EEQ + E E+Q+L +E D +
Sbjct: 1726 REEEQLRQETEQEQLRRQERYRKI-LEEEQLRPEREEQQLRR----QERDRKFREEEQLR 1780
Query: 1314 HDADDEDDGHLESTKKKELEEQPTREDVKEEPGVQESFLDA---------NMQKSREKIK 1364
+ +++ ES +K EEQ +E +EE ++ D +++ ++++
Sbjct: 1781 QEREEQQLRSQESDRKFREEEQLRQE--REEQQLRPQQRDGKYRWEEEQLQLEEQEQRLR 1838
Query: 1365 DKEETELDSEEEQPSHDTSVVSEQMAGSEDD----HEEDSHTKEELIELKEEEEIPHSEL 1420
+ + + +EE+ + + S EQ E++ E + +EE I +++EE H ++
Sbjct: 1839 QERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKEEQRHRQV 1898
Score = 65.1 bits (157), Expect = 7e-10
Identities = 61/294 (20%), Positives = 127/294 (43%), Gaps = 19/294 (6%)
Query: 1203 KIQESEETVEPKEDMPLPEERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSNSPE 1262
++ E EE E +E + + ++ +EE+ + +E +E EE A ++ + ++ P+
Sbjct: 147 ELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPD 206
Query: 1263 TET-KEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDEDD 1321
E + E+ E K R E+Q+Q E Q + + E E+E + ++ +E+
Sbjct: 207 EEQLRRRELLELRRKGR-EEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEP 265
Query: 1322 GHLESTKKKE-----LEEQPTREDVKEEPGVQESFLDANMQKSREKIKDKEETELDSEEE 1376
+++E LE Q R + +EE Q+ + +++ + +E+ E E++
Sbjct: 266 QRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQ 325
Query: 1377 QPSHDTSVVSEQMAGSEDD--------HEEDSHTKEELIELKEEEEIPHSELDLE-TVQA 1427
+ EQ E + E++ +E+ + ++EEE +L E ++
Sbjct: 326 ERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRR 385
Query: 1428 VQSLTQEESSEHEGAYQDCEETLAACQTLQSYTQADEDPQM--SMVEDCHASEH 1479
Q L +E+ E + E+ L Q L+ Q + Q+ E+ H +H
Sbjct: 386 EQQLRREQQLRREQQLRR-EQQLRREQQLRREQQLRREQQLRREQEEERHEQKH 438
Score = 57.0 bits (136), Expect = 2e-07
Identities = 56/245 (22%), Positives = 106/245 (43%), Gaps = 16/245 (6%)
Query: 1205 QESEETVEPKEDMPLPEERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSNSPETE 1264
+E + KE + L + R+EE++ + E + + EE + + + E
Sbjct: 97 EEKRARCDGKESL-LQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQS 155
Query: 1265 TKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDH-DADDEDDGH 1323
K+ +E+ + + R E RQ +E QE EE EEE+ + + + ++ D +
Sbjct: 156 EKQERLEQRDRQRRDEELWRQ-RQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRE 214
Query: 1324 LESTKKKELEEQPTREDVKEEPGVQESFLDANMQKSREKIKDKEETELDSEEEQPSHDTS 1383
L ++K EE+ + +++ QE + + RE + KEE +L EE Q +
Sbjct: 215 LLELRRKGREEKQQQRRERQDRVFQEE--EEKEWRKRETVLRKEEEKLQEEEPQRQRELQ 272
Query: 1384 VVSEQMAGSEDDHEEDSHTKEELIELKEEEEIPHSELDLETVQAVQSLTQEESSEHEGAY 1443
EQ+ E ++EL ++EEE L E Q ++ +EE E +
Sbjct: 273 EEEEQLRKLE---------RQELRRERQEEEQQQQRLRRE--QQLRRKQEEERREQQEER 321
Query: 1444 QDCEE 1448
++ +E
Sbjct: 322 REQQE 326
Score = 52.8 bits (125), Expect = 3e-06
Identities = 106/587 (18%), Positives = 227/587 (38%), Gaps = 83/587 (14%)
Query: 789 EEEEEAEEGENEEPQCQERELEISVGKSVSHENKEQDSYSVESEKK-PEVMAPVSSTRLS 847
+E E E ++ +CQERE ++ + +EQ E ++K E V
Sbjct: 1386 QERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERE 1445
Query: 848 KQVLPHDSLPANSQPSRRGRWGRKNRKTQERFG------DKDSKLLLEETSSAPQEQ--- 898
++ L + + R ++ + + QER ++D K L EE QE+
Sbjct: 1446 RKFLEEEQ---QLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRK 1502
Query: 899 YGECGEKSEATQEQYTESEEQLVASEEQPSQDGKPDLPKRRLSEGVEPWRGQLKKSPEAL 958
+ E +S+ + ++ E E+QL + Q + + + RR G + + + +K E
Sbjct: 1503 FREQELRSQEPERKFLEEEQQLHRQQRQ-RKFLQEEQQLRRQERGQQRRQDRDRKFREEE 1561
Query: 959 KCRLTEGSERLPR-----RYSEGDRAVLRGFSESSEEEEEPESPRSSSPPILTKPTLKRK 1013
+ R ++L R ++ ++ V R E E+E + R L + +R
Sbjct: 1562 QLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQ---ERD 1618
Query: 1014 KPFLHRRRRVRKRKH---HNSSVVTETISETTEVLDEPFEDS---DSERPMPRLEPTFEI 1067
+ F + +++R+ H + + E ++ + E D +R E +
Sbjct: 1619 RKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQE 1678
Query: 1068 DEEEE----------EEDENELFPREYFRRLSSQDVLRCQSSSKRKSKDEEEDEESDDAD 1117
EE++ E+E +L +E R+ ++ + +RK ++EE+ + + +
Sbjct: 1679 GEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQE 1738
Query: 1118 DTPILKPVSLLRKRDVKNSPLEPDTSTPLKKKKGWPKGKSRKPIHWKKRPGRKPGFKLSR 1177
LR+++ LE + P ++++ + + + +++ + R
Sbjct: 1739 Q---------LRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQ------LRQER 1783
Query: 1178 EIMPVSTQACVIEPIVSIPKAGRKPKIQESEETVEPKEDMPL-PEERK-----EEEEMQA 1231
E + +Q K +E E+ + +E+ L P++R EEE++Q
Sbjct: 1784 EEQQLRSQES-------------DRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQL 1830
Query: 1232 EAEEAEEGEEEDAASSEVPAASPADSSNSPETETKEPEVEEEEEKPRVSEEQRQSEEEQQ 1291
E +E +E D + T+E EE+E + E++R+ E E++
Sbjct: 1831 EEQEQRLRQERDRQYRA-----------EEQFATQEKSRREEQELWQEEEQKRRQERERK 1879
Query: 1292 ELEEPEPEEEEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQPTR 1338
EE ++++ + + + G L + P R
Sbjct: 1880 LREEHIRRQQKEEQRHRQVGEIKSQEGKGHGRLLEPGTHQFASVPVR 1926
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 85.5 bits (210), Expect = 5e-16
Identities = 129/612 (21%), Positives = 252/612 (41%), Gaps = 85/612 (13%)
Query: 796 EGENEEPQCQERELEISVGKSVSHENKEQDSYSVESEKKPEVMAPVSSTRLSKQVLPHDS 855
E EE ++++ + GK S ++ + + + K + P ++ D
Sbjct: 85 ENNEEEFTSKDKKKKGQKGKKQSFDDNDSEELEDKDSKSKKTAKP----KVEMYSGSDDD 140
Query: 856 LPANSQPSR-RGRWGRKNRKTQERFGDKDSKLLLEETSSAPQEQYGECGEKSEATQEQYT 914
N P + +G+ + N+K D+D+ ++E S GE G++S+ ++
Sbjct: 141 DDFNKLPKKAKGKAQKSNKKWDGSEEDEDNSKKIKERSRINSS--GESGDESD----EFL 194
Query: 915 ESEEQLVASEEQPSQDGKPDLPKRRLSEGVEPWRGQLKKSPEALKCRLTEGSERLPRRYS 974
+S + ++ +Q KP + G E K A K E ER R+
Sbjct: 195 QSRKG-----QKKNQKNKPG---PNIESGNEDDDASFKIKTVAQK--KAEKKER-ERKKR 243
Query: 975 EGDRAVLRGFSESSEEE--EEPESPRSSSPPILTKPTLKRKKPFLHRRRRVRKRKHHNSS 1032
+ ++A LR E E E ++ +S + S + T+K K +
Sbjct: 244 DEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEETVKSKV-----------------T 286
Query: 1033 VVTETISETTEVLDEPFE-DSDSERPMPRLEPTFEIDEEEEEEDENELFPREYFRRLSSQ 1091
V T I + E + P + D+E + + + E+EE+E E + P S+
Sbjct: 287 VDTGVIPASEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGP--------SK 338
Query: 1092 DVLRCQSSSKRKSKDEEEDEESDDADDTPILKPVSLLRKRDVKNSPLEPDTSTPLKKKKG 1151
++ + K K+EEE ++ ++ + L+ + RK + + LE + K+K+
Sbjct: 339 ATVKAMQEALAKLKEEEERQKREEEERIKRLEELEAKRKEEER---LEQEKRERKKQKEK 395
Query: 1152 WPKGKSRKPIHWKKRPGRKPGFKLSREIMPVSTQACVIEPIVSIPKAG------RKPKIQ 1205
K + +K + R+ + + + Q + S+PK ++ KI
Sbjct: 396 ERKERLKKEGKLLTKSQREARARAEATLKLLQAQGVEVPSKDSLPKKRPIYEDKKRKKIP 455
Query: 1206 ESEETVEPKEDMPL-------PEERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPADSS 1258
+ E+ E E M L + E+EE E EE + EDA + A + + +
Sbjct: 456 QQLESKEVSESMELCAAVEVMEQGVPEKEETPPPVEPEEEEDTEDAGLDDWEAMASDEET 515
Query: 1259 NSPETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADD 1318
E EV+E E+ EE+ + +EE +E EE EE E +E + D+ +D+
Sbjct: 516 EKVEGNKVHIEVKENPEEEEEEEEEEEEDEESEEEEE---EEGESEGSEGDEEDEKVSDE 572
Query: 1319 EDDGHLESTKKKELEEQPTREDVKEEPGVQESFLDANMQKSR-EKIKDKEETELDSEEEQ 1377
+D G K L+++P++E +S D++ +++ E+ DK + + E+ +
Sbjct: 573 KDSG-------KTLDKKPSKE------MSSDSEYDSDDDRTKEERAYDKAKRRI--EKRR 617
Query: 1378 PSHDTSVVSEQM 1389
H +V +E++
Sbjct: 618 LEHSKNVNTEKL 629
Score = 84.3 bits (207), Expect = 1e-15
Identities = 133/627 (21%), Positives = 241/627 (38%), Gaps = 102/627 (16%)
Query: 858 ANSQPSRRGRWGRKNRKTQERFGDKDSKLLLEETSSAPQEQYGECGEKSEATQEQYTESE 917
A Q ++ + +K K ++ F + D +L+E E G ++ + +E
Sbjct: 32 AKEQEPQKSKGKKKKEKKKQDFDEDD---ILKELEELSLEAQGIKADRETVAVKPTENNE 88
Query: 918 EQLVASEEQPS-QDGKPDLPKRRLSEGVEPWRGQLKKSPEALKCRLTEGSE------RLP 970
E+ + +++ Q GK SE +E + KK+ + K + GS+ +LP
Sbjct: 89 EEFTSKDKKKKGQKGKKQSFDDNDSEELEDKDSKSKKTAKP-KVEMYSGSDDDDDFNKLP 147
Query: 971 RRYSEGDRAVLRGFSESSEEEEEPESPRSSSPPILTKPTLKRKKPFLHRRRRVRKRKHHN 1030
++ + + + S E+E+ + + S + + FL R+ +K + +
Sbjct: 148 KKAKGKAQKSNKKWDGSEEDEDNSKKIKERSRINSSGESGDESDEFLQSRKGQKKNQKNK 207
Query: 1031 SSVVTETISETTEVLDEPFEDSDSERPMPRLEPTFEIDEEEEEEDENELFPREYFRRLSS 1090
E+ +E +D S + + E E E ++ + E + R+L
Sbjct: 208 PGPNIESGNE---------DDDASFKIKTVAQKKAEKKERERKKRDEE---KAKLRKLKE 255
Query: 1091 QDVLRCQSSSKRKSKD-----EEEDEESDDADDTPILKPVSLLRKRDVKNSPLEPDTSTP 1145
++ L + K K+ EEE +S DT ++ P S K + + + +
Sbjct: 256 KEELETGKKDQSKQKESQRKFEEETVKSKVTVDTGVI-PASE-EKAETPTAAEDDNEGDK 313
Query: 1146 LKKKKGWPKGKSRKPIHWKKRPGRKPGFKLSREIMPVSTQACVIEPIVSIPKAGRKPKIQ 1205
KK K KG+ + KK+ K K +E ++ K + + Q
Sbjct: 314 KKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQE---------------ALAKLKEEEERQ 358
Query: 1206 ESEETVEPKEDMPLPEERKEEEEMQAEAEEAEEGEEED---------------------- 1243
+ EE K L +RKEEE ++ E E ++ +E++
Sbjct: 359 KREEEERIKRLEELEAKRKEEERLEQEKRERKKQKEKERKERLKKEGKLLTKSQREARAR 418
Query: 1244 ---------AASSEVPAASPADSSNSPETETKEPEVEEEEEKPRVSEEQR---------Q 1285
A EVP+ + K ++ ++ E VSE Q
Sbjct: 419 AEATLKLLQAQGVEVPSKDSLPKKRPIYEDKKRKKIPQQLESKEVSESMELCAAVEVMEQ 478
Query: 1286 SEEEQQELEEP-EPEEEEDAAAETAQNDDHDA--DDEDDGHLESTKKK-ELEEQPTREDV 1341
E++E P EPEEEED E A DD +A DE+ +E K E++E P E+
Sbjct: 479 GVPEKEETPPPVEPEEEEDT--EDAGLDDWEAMASDEETEKVEGNKVHIEVKENPEEEEE 536
Query: 1342 KEEPGVQESFLDANMQKSREKIKDKEETELDSEEEQPSHDTSV-------VSEQMAGSED 1394
+EE E D ++ E+ + E +E D E+E+ S + S++M+ +
Sbjct: 537 EEE----EEEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPSKEMSSDSE 592
Query: 1395 DHEEDSHTKEELIELKEEEEIPHSELD 1421
+D TKEE K + I L+
Sbjct: 593 YDSDDDRTKEERAYDKAKRRIEKRRLE 619
Score = 78.2 bits (191), Expect = 8e-14
Identities = 126/591 (21%), Positives = 235/591 (39%), Gaps = 90/591 (15%)
Query: 953 KSPEALKCRLTEGSERLPRRYSEGDRAVLRGFSESSEEEEEPESPRSSSPPILTKPTLKR 1012
K E K + + E+ + + E D +L+ E S E + ++ R + + KPT
Sbjct: 33 KEQEPQKSKGKKKKEKKKQDFDEDD--ILKELEELSLEAQGIKADRET---VAVKPTENN 87
Query: 1013 KKPFLHRRRRVRKRKHHNSSVVTETISETTEVLDEPFEDSDSERPMPRLEPTFEIDEEEE 1072
++ F + ++ + +K S E ED DS + +P E+ +
Sbjct: 88 EEEFTSKDKKKKGQKGKKQSFDDND--------SEELEDKDS-KSKKTAKPKVEMYSGSD 138
Query: 1073 EEDENELFPREYFRRLSSQDVLRCQSSSKRKSKDEEEDEES-------------DDADDT 1119
++D+ F +L + + Q S+K+ EE+++ S + D++
Sbjct: 139 DDDD--------FNKLPKKAKGKAQKSNKKWDGSEEDEDNSKKIKERSRINSSGESGDES 190
Query: 1120 PILKPVSLLRKRDVKNSPL------EPDTSTPLKKKKGWPKGKSRKPIHWKKRPGRKPGF 1173
+K++ KN P D K K K +K KKR K
Sbjct: 191 DEFLQSRKGQKKNQKNKPGPNIESGNEDDDASFKIKTVAQKKAEKKERERKKRDEEKAKL 250
Query: 1174 KLSREIMPVST---------------QACVIEPIVSIPKAGRKPKIQESEET-VEPKEDM 1217
+ +E + T + ++ V++ G P +E ET ++D
Sbjct: 251 RKLKEKEELETGKKDQSKQKESQRKFEEETVKSKVTVD-TGVIPASEEKAETPTAAEDDN 309
Query: 1218 PLPEERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSNSPETETKEPEVEE----- 1272
+++K++++ + E EE E+ +++ + + V A A + E E ++ E EE
Sbjct: 310 EGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERIKRL 369
Query: 1273 EEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAE--TAQNDDHDADDEDDGHLESTKKK 1330
EE + + EE+R +E+++ ++ E E +E E +A + L+ + +
Sbjct: 370 EELEAKRKEEERLEQEKRERKKQKEKERKERLKKEGKLLTKSQREARARAEATLKLLQAQ 429
Query: 1331 ELE---------EQPTREDVK--------EEPGVQESF-LDANMQKSREKIKDKEETE-- 1370
+E ++P ED K E V ES L A ++ + + +KEET
Sbjct: 430 GVEVPSKDSLPKKRPIYEDKKRKKIPQQLESKEVSESMELCAAVEVMEQGVPEKEETPPP 489
Query: 1371 LDSEEEQPSHDTSVVSEQMAGSEDDHEEDSHTKEELIELKEEEEIPHSELDLETVQAVQS 1430
++ EEE+ + D + + S+++ E+ K IE+KE E E + E
Sbjct: 490 VEPEEEEDTEDAGLDDWEAMASDEETEKVEGNKVH-IEVKENPEEEEEEEEEEEEDEESE 548
Query: 1431 LTQEESSEHEGAYQDCEETLAACQTLQSYTQADEDPQMSMVEDCHASEHNS 1481
+EE E EG+ D EE S D+ P M D SE++S
Sbjct: 549 EEEEEEGESEGSEGD-EEDEKVSDEKDSGKTLDKKPSKEMSSD---SEYDS 595
Score = 35.8 bits (81), Expect = 0.43
Identities = 63/307 (20%), Positives = 113/307 (36%), Gaps = 59/307 (19%)
Query: 788 EEEEEEAEEGEN---------------EEPQCQERELEISVGKSVSHENKEQDSYSVESE 832
EE+E+E ++G + EE + Q+RE E + + E K ++ +E E
Sbjct: 326 EEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERIKRLEELEAKRKEEERLEQE 385
Query: 833 KKPEVMAPVSSTRLSKQVLPHDSLPANSQPSRRGRWGRKNRKTQER-------------- 878
K+ + +++ L SQ R R + Q +
Sbjct: 386 KRERKKQKEKERK--ERLKKEGKLLTKSQREARARAEATLKLLQAQGVEVPSKDSLPKKR 443
Query: 879 --FGDKDSKLLLEETSSAPQEQYGECGEKSEATQEQYTESEE---QLVASEEQPSQD-GK 932
+ DK K + ++ S + E E ++ E EE + EE+ ++D G
Sbjct: 444 PIYEDKKRKKIPQQLESKEVSESMELCAAVEVMEQGVPEKEETPPPVEPEEEEDTEDAGL 503
Query: 933 PDLPKRRLSEGVEPWRG-----QLKKSPEALKCRLTEGSERLPRRYSEGDRAVLRGFSES 987
D E E G ++K++PE + E E E + G SE
Sbjct: 504 DDWEAMASDEETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEESEEEEEEEGESEG-SEG 562
Query: 988 SEEEEEPESPRSSSPPILTKPT---------------LKRKKPFLHRRRRVRKRK-HHNS 1031
EE+E+ + S + KP+ K ++ + +RR+ KR+ H+
Sbjct: 563 DEEDEKVSDEKDSGKTLDKKPSKEMSSDSEYDSDDDRTKEERAYDKAKRRIEKRRLEHSK 622
Query: 1032 SVVTETI 1038
+V TE +
Sbjct: 623 NVNTEKL 629
Score = 32.0 bits (71), Expect = 6.3
Identities = 20/48 (41%), Positives = 23/48 (47%), Gaps = 1/48 (2%)
Query: 786 VSEEEEEEAEEGENEEPQCQERELEISVGKSVSHENKEQDSYSVESEK 833
V E EEE EE E EE + E E G+S E E+D V EK
Sbjct: 527 VKENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDE-KVSDEK 573
>gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]
Length = 2454
Score = 85.1 bits (209), Expect = 6e-16
Identities = 137/658 (20%), Positives = 254/658 (38%), Gaps = 91/658 (13%)
Query: 806 ERELEISVGKSVSHENKEQDSYSVESEKKPEVMAPVSSTRLSKQVLPHDSLPANSQ--PS 863
E+ L+ S ++K+Q E +KKP ++ K ++S ++ P
Sbjct: 928 EKFLKKDQSDETSEDDKKQSKKGTEEKKKPSDF----KKKVIKMEQQYESSSDGTEKLPE 983
Query: 864 RRGRW----GRKNRKTQERFGDKDSKLLLEETSSAPQEQYGECGEKSEATQEQYTESEEQ 919
R G K K G+K SK + ++TS +++ + EKS T +
Sbjct: 984 REEICHFPKGIKQIKNGTTDGEKKSKKIRDKTSKK-KDELSDYAEKS-------TGKGDS 1035
Query: 920 LVASEEQPSQDGKPDLPKRRLSE-GVEPWRGQLKKSPEALKCRLTE-GSERLPRRYSEGD 977
+SE++ S++G K+R G + Q S + K + E G +R +
Sbjct: 1036 CDSSEDKKSKNGAYGREKKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIE 1095
Query: 978 RAVLRGFSESSEEEEEPESPRSSSPPILTKPTLKRKKPFLHRRRRVRKRKHHNSSVVTET 1037
R S +E SS ++ K+K+ +++ V ++ +S+ T T
Sbjct: 1096 LRERRNLSSKRNTKEIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTST 1155
Query: 1038 ISETTEVLDEPFEDSDSERPMPRLEPTFEIDEEEEEEDENELFPREYFRRLSSQDVLRCQ 1097
+ ++ D +E + E DE ++ P LSS
Sbjct: 1156 KRKQADITSSSSSD---------IEDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQS 1206
Query: 1098 SSSKRKSKDEEEDEESDDADDTPILKPVSLLRKRDVK-NSPLEPDTSTPLKKKKGWPKGK 1156
S + SK + DD D+ P + + ++K N + D S+ + ++G
Sbjct: 1207 SGDEALSKSVPVTVDDDDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPEEG----- 1261
Query: 1157 SRKPIHWKKRPGRK----PGFKLSREIMPVSTQACVIEPIVSIPKAGRKPKIQE------ 1206
KKR G++ PG + ++ + + S + +KP+ +
Sbjct: 1262 -------KKRTGKQNEENPGDEEAKNQVNSESD--------SDSEESKKPRYRHRLLRHK 1306
Query: 1207 ---------SEETVEPKEDMPLP--EERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPA 1255
E+ +PKE + RK E +++ E G E+ + SE
Sbjct: 1307 LTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRT 1366
Query: 1256 DSSNSPETETKEPEVEEEEEKPRV-------SEEQRQSEEEQQELEEPEPEEEEDAAAET 1308
S+ E E + ++++++ R+ SE + SEEE++E EE E EEEE+ E
Sbjct: 1367 RSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEE 1426
Query: 1309 AQNDDHDADDEDDGHLESTKKKELEEQPTREDVKEEPGVQESFLDANMQKSREKIKDKEE 1368
+NDD + + + K + T+ +KEE ++ A ++ REK+++ E
Sbjct: 1427 DENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEEEERRKRI--AEREREREKLREVIE 1484
Query: 1369 TELDSEEEQPSHDTSVVSEQMAGSEDDHEEDSHTKEELIELKEEEEIPHSELDLETVQ 1426
E S + P V+ +ED TKE L+++ I ++ VQ
Sbjct: 1485 IEDASPTKCPITTKLVL-----------DEDEETKEPLVQVHRNMVIKLKPHQVDGVQ 1531
Score = 42.7 bits (99), Expect = 0.004
Identities = 68/364 (18%), Positives = 137/364 (37%), Gaps = 27/364 (7%)
Query: 1098 SSSKRKSKDEEEDEESDDADDTPILKPVSLLR--KRDVKNSPLEPDTSTPLKKKKGWPKG 1155
S KR+++ E + +S+ + + + R K+ + N+ + D+S K K
Sbjct: 766 SKKKRQTQSESSNYDSELEKEIKSMSKIGAARTTKKRIPNTK-DFDSSEDEKHSKKGMDN 824
Query: 1156 KSRKPIHWKKRPGRKPGFKLSREIMPVSTQACVIEPIVSIPKAGRKPKIQESEETVEPKE 1215
+ K + + + S + V + + R PK Q++ + + +
Sbjct: 825 QGHKNLKTSQEGSSDDAERKQERETFSSAEGTVDKDTTIMELRDRLPKKQQASASTDGVD 884
Query: 1216 DMPLPEERKEEEEMQAEAEEAEEGEE---------EDAASSEVPAASPADSSNSPETETK 1266
+ E+ E++ AE E+ + +D S D S+ + K
Sbjct: 885 KLSGKEQSFTSLEVRKVAETKEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDK 944
Query: 1267 EPEVEEEEEKPRVSEEQRQSEEEQQELE------EPEPEEEE----DAAAETAQNDDHDA 1316
+ + EEK + S+ +++ + +Q+ E E PE EE + +N D
Sbjct: 945 KQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFPKGIKQIKNGTTDG 1004
Query: 1317 DDEDDGHLESTKKKELEEQPTREDVKEEPGVQESFLDANMQKSREKI--KDKEETELDSE 1374
+ + + T KK+ E E + G +S + +KS+ ++K+ +L +
Sbjct: 1005 EKKSKKIRDKTSKKKDELSDYAE---KSTGKGDSCDSSEDKKSKNGAYGREKKRCKLLGK 1061
Query: 1375 EEQPSHDTSVVSEQMAGSEDDHEEDSHTKEELIELKEEEEIPHSELDLETVQAVQSLTQE 1434
+ D S + ++D S + + IEL+E + E S E
Sbjct: 1062 SSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRNTKEIQSGSSSSDAE 1121
Query: 1435 ESSE 1438
ESSE
Sbjct: 1122 ESSE 1125
Score = 34.7 bits (78), Expect = 0.96
Identities = 40/223 (17%), Positives = 88/223 (39%), Gaps = 6/223 (2%)
Query: 1197 KAGRKPKIQESEETVEPKEDMPLPEE--RKEEEEMQAEAEEAEEGEEEDAASSEVPAASP 1254
K RK K S + K+ K++ + Q+E+ + E++ S A+
Sbjct: 738 KGKRKRKSSTSGSDFDTKKGKSAKSSIISKKKRQTQSESSNYDSELEKEIKSMSKIGAAR 797
Query: 1255 ADSSNSPETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDH 1314
P T+ + +E+ K + + ++ + QE + E +++ ET + +
Sbjct: 798 TTKKRIPNTKDFDSSEDEKHSKKGMDNQGHKNLKTSQEGSSDDAERKQE--RETFSSAEG 855
Query: 1315 DAD-DEDDGHLESTKKKELEEQPTREDVKEEPGVQESFLDANMQKSREKIKDKEETELDS 1373
D D L K+ + + + V + G ++SF ++K E K+K +
Sbjct: 856 TVDKDTTIMELRDRLPKKQQASASTDGVDKLSGKEQSFTSLEVRKVAE-TKEKSKHLKTK 914
Query: 1374 EEEQPSHDTSVVSEQMAGSEDDHEEDSHTKEELIELKEEEEIP 1416
++ S ++E+ + E K++ + EE++ P
Sbjct: 915 TCKKVQDGLSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKKKP 957
Score = 33.9 bits (76), Expect = 1.6
Identities = 33/139 (23%), Positives = 59/139 (42%), Gaps = 26/139 (18%)
Query: 783 NSVVSEEEEEEAEEGENEEPQCQERELEISVGKSVSHENKEQDSYSVESEKKPEVMAPVS 842
N SEEEEEE EE E EE + +E E E++ DS S P
Sbjct: 1400 NKSNSEEEEEEKEEEEEEEEEEEEEE-----------EDENDDSKS-----------PGK 1437
Query: 843 STRLSKQVLPHDSLPANSQPSRRGRWGRKNRKTQERFGDKDSKLLLEETSSAPQEQYGEC 902
+ +++L D L +Q + + R+ R + + + ++E ++P +C
Sbjct: 1438 GRKKIRKILKDDKLRTETQNALKEEEERRKRIAEREREREKLREVIEIEDASPT----KC 1493
Query: 903 GEKSEATQEQYTESEEQLV 921
++ ++ E++E LV
Sbjct: 1494 PITTKLVLDEDEETKEPLV 1512
>gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]
Length = 2492
Score = 85.1 bits (209), Expect = 6e-16
Identities = 137/658 (20%), Positives = 254/658 (38%), Gaps = 91/658 (13%)
Query: 806 ERELEISVGKSVSHENKEQDSYSVESEKKPEVMAPVSSTRLSKQVLPHDSLPANSQ--PS 863
E+ L+ S ++K+Q E +KKP ++ K ++S ++ P
Sbjct: 966 EKFLKKDQSDETSEDDKKQSKKGTEEKKKPSDF----KKKVIKMEQQYESSSDGTEKLPE 1021
Query: 864 RRGRW----GRKNRKTQERFGDKDSKLLLEETSSAPQEQYGECGEKSEATQEQYTESEEQ 919
R G K K G+K SK + ++TS +++ + EKS T +
Sbjct: 1022 REEICHFPKGIKQIKNGTTDGEKKSKKIRDKTSKK-KDELSDYAEKS-------TGKGDS 1073
Query: 920 LVASEEQPSQDGKPDLPKRRLSE-GVEPWRGQLKKSPEALKCRLTE-GSERLPRRYSEGD 977
+SE++ S++G K+R G + Q S + K + E G +R +
Sbjct: 1074 CDSSEDKKSKNGAYGREKKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIE 1133
Query: 978 RAVLRGFSESSEEEEEPESPRSSSPPILTKPTLKRKKPFLHRRRRVRKRKHHNSSVVTET 1037
R S +E SS ++ K+K+ +++ V ++ +S+ T T
Sbjct: 1134 LRERRNLSSKRNTKEIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTST 1193
Query: 1038 ISETTEVLDEPFEDSDSERPMPRLEPTFEIDEEEEEEDENELFPREYFRRLSSQDVLRCQ 1097
+ ++ D +E + E DE ++ P LSS
Sbjct: 1194 KRKQADITSSSSSD---------IEDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQS 1244
Query: 1098 SSSKRKSKDEEEDEESDDADDTPILKPVSLLRKRDVK-NSPLEPDTSTPLKKKKGWPKGK 1156
S + SK + DD D+ P + + ++K N + D S+ + ++G
Sbjct: 1245 SGDEALSKSVPVTVDDDDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPEEG----- 1299
Query: 1157 SRKPIHWKKRPGRK----PGFKLSREIMPVSTQACVIEPIVSIPKAGRKPKIQE------ 1206
KKR G++ PG + ++ + + S + +KP+ +
Sbjct: 1300 -------KKRTGKQNEENPGDEEAKNQVNSESD--------SDSEESKKPRYRHRLLRHK 1344
Query: 1207 ---------SEETVEPKEDMPLP--EERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPA 1255
E+ +PKE + RK E +++ E G E+ + SE
Sbjct: 1345 LTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRT 1404
Query: 1256 DSSNSPETETKEPEVEEEEEKPRV-------SEEQRQSEEEQQELEEPEPEEEEDAAAET 1308
S+ E E + ++++++ R+ SE + SEEE++E EE E EEEE+ E
Sbjct: 1405 RSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEE 1464
Query: 1309 AQNDDHDADDEDDGHLESTKKKELEEQPTREDVKEEPGVQESFLDANMQKSREKIKDKEE 1368
+NDD + + + K + T+ +KEE ++ A ++ REK+++ E
Sbjct: 1465 DENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEEEERRKRI--AEREREREKLREVIE 1522
Query: 1369 TELDSEEEQPSHDTSVVSEQMAGSEDDHEEDSHTKEELIELKEEEEIPHSELDLETVQ 1426
E S + P V+ +ED TKE L+++ I ++ VQ
Sbjct: 1523 IEDASPTKCPITTKLVL-----------DEDEETKEPLVQVHRNMVIKLKPHQVDGVQ 1569
Score = 42.7 bits (99), Expect = 0.004
Identities = 68/364 (18%), Positives = 137/364 (37%), Gaps = 27/364 (7%)
Query: 1098 SSSKRKSKDEEEDEESDDADDTPILKPVSLLR--KRDVKNSPLEPDTSTPLKKKKGWPKG 1155
S KR+++ E + +S+ + + + R K+ + N+ + D+S K K
Sbjct: 804 SKKKRQTQSESSNYDSELEKEIKSMSKIGAARTTKKRIPNTK-DFDSSEDEKHSKKGMDN 862
Query: 1156 KSRKPIHWKKRPGRKPGFKLSREIMPVSTQACVIEPIVSIPKAGRKPKIQESEETVEPKE 1215
+ K + + + S + V + + R PK Q++ + + +
Sbjct: 863 QGHKNLKTSQEGSSDDAERKQERETFSSAEGTVDKDTTIMELRDRLPKKQQASASTDGVD 922
Query: 1216 DMPLPEERKEEEEMQAEAEEAEEGEE---------EDAASSEVPAASPADSSNSPETETK 1266
+ E+ E++ AE E+ + +D S D S+ + K
Sbjct: 923 KLSGKEQSFTSLEVRKVAETKEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDK 982
Query: 1267 EPEVEEEEEKPRVSEEQRQSEEEQQELE------EPEPEEEE----DAAAETAQNDDHDA 1316
+ + EEK + S+ +++ + +Q+ E E PE EE + +N D
Sbjct: 983 KQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFPKGIKQIKNGTTDG 1042
Query: 1317 DDEDDGHLESTKKKELEEQPTREDVKEEPGVQESFLDANMQKSREKI--KDKEETELDSE 1374
+ + + T KK+ E E + G +S + +KS+ ++K+ +L +
Sbjct: 1043 EKKSKKIRDKTSKKKDELSDYAE---KSTGKGDSCDSSEDKKSKNGAYGREKKRCKLLGK 1099
Query: 1375 EEQPSHDTSVVSEQMAGSEDDHEEDSHTKEELIELKEEEEIPHSELDLETVQAVQSLTQE 1434
+ D S + ++D S + + IEL+E + E S E
Sbjct: 1100 SSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRNTKEIQSGSSSSDAE 1159
Query: 1435 ESSE 1438
ESSE
Sbjct: 1160 ESSE 1163
Score = 36.6 bits (83), Expect = 0.25
Identities = 43/173 (24%), Positives = 68/173 (39%), Gaps = 15/173 (8%)
Query: 1233 AEEAEEGEEEDA----ASSEVPAASPADSSNSPETETKEPEVEEEEEKPRVSEEQRQSEE 1288
A +EE EE + A ++ SNS E + E EK + S R +
Sbjct: 23 AHSSEESEETSSPPRLAMNQNTDKISGSGSNSDMMENSKEEGTSSSEKSKSSGSSRSKRK 82
Query: 1289 EQQELEEPEPEEEEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQPTREDVKEEPGVQ 1348
+ E ++E+ ET D + + E+D ++S K + QP EP +
Sbjct: 83 PSIVTKYVESDDEKPLDDETVNEDASNENSENDITMQSLPKGTVIVQP-------EPVLN 135
Query: 1349 ESFLDANMQKSREKIKDKEETELDSEEEQPSHDTSVVSEQMAGSEDDH-EEDS 1400
E D + R + K K E L E H +VS G + +H ++DS
Sbjct: 136 EDKDDFKGPEFRSRSKMKTE-NLKKRGEDGLH--GIVSCTACGQQVNHFQKDS 185
Score = 34.7 bits (78), Expect = 0.96
Identities = 40/223 (17%), Positives = 88/223 (39%), Gaps = 6/223 (2%)
Query: 1197 KAGRKPKIQESEETVEPKEDMPLPEE--RKEEEEMQAEAEEAEEGEEEDAASSEVPAASP 1254
K RK K S + K+ K++ + Q+E+ + E++ S A+
Sbjct: 776 KGKRKRKSSTSGSDFDTKKGKSAKSSIISKKKRQTQSESSNYDSELEKEIKSMSKIGAAR 835
Query: 1255 ADSSNSPETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDH 1314
P T+ + +E+ K + + ++ + QE + E +++ ET + +
Sbjct: 836 TTKKRIPNTKDFDSSEDEKHSKKGMDNQGHKNLKTSQEGSSDDAERKQE--RETFSSAEG 893
Query: 1315 DAD-DEDDGHLESTKKKELEEQPTREDVKEEPGVQESFLDANMQKSREKIKDKEETELDS 1373
D D L K+ + + + V + G ++SF ++K E K+K +
Sbjct: 894 TVDKDTTIMELRDRLPKKQQASASTDGVDKLSGKEQSFTSLEVRKVAE-TKEKSKHLKTK 952
Query: 1374 EEEQPSHDTSVVSEQMAGSEDDHEEDSHTKEELIELKEEEEIP 1416
++ S ++E+ + E K++ + EE++ P
Sbjct: 953 TCKKVQDGLSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKKKP 995
Score = 33.9 bits (76), Expect = 1.6
Identities = 33/139 (23%), Positives = 59/139 (42%), Gaps = 26/139 (18%)
Query: 783 NSVVSEEEEEEAEEGENEEPQCQERELEISVGKSVSHENKEQDSYSVESEKKPEVMAPVS 842
N SEEEEEE EE E EE + +E E E++ DS S P
Sbjct: 1438 NKSNSEEEEEEKEEEEEEEEEEEEEE-----------EDENDDSKS-----------PGK 1475
Query: 843 STRLSKQVLPHDSLPANSQPSRRGRWGRKNRKTQERFGDKDSKLLLEETSSAPQEQYGEC 902
+ +++L D L +Q + + R+ R + + + ++E ++P +C
Sbjct: 1476 GRKKIRKILKDDKLRTETQNALKEEEERRKRIAEREREREKLREVIEIEDASPT----KC 1531
Query: 903 GEKSEATQEQYTESEEQLV 921
++ ++ E++E LV
Sbjct: 1532 PITTKLVLDEDEETKEPLV 1550
>gi|114431236 zinc finger protein 462 [Homo sapiens]
Length = 2506
Score = 84.7 bits (208), Expect = 8e-16
Identities = 52/108 (48%), Positives = 57/108 (52%), Gaps = 8/108 (7%)
Query: 1611 SMGSSCSMMQQSSVQPAANCSIKSPQSCVVERPPSNQQQQPPPPPPQQPQPPPPQPQPAP 1670
S S S V + SI +S V+ P QQQQPP PPP P PPP QPQP
Sbjct: 504 SQSESISSSLNEGVVSYESSSINGRKSGVMLDPL--QQQQPPQPPPPPPPPPPSQPQPLQ 561
Query: 1671 QPPPPQQQPQQQPQPQPQ-QPPP---PPPPQQQPPLS--QCSMNNSFT 1712
QP PPQ QP Q PQPQ QPPP P PP Q PL +C+M N T
Sbjct: 562 QPQPPQLQPPHQVPPQPQTQPPPTQQPQPPTQAAPLHPYKCTMCNYST 609
Score = 40.8 bits (94), Expect = 0.013
Identities = 20/49 (40%), Positives = 21/49 (42%)
Query: 1673 PPPQQQPQQQPQPQPQQPPPPPPPQQQPPLSQCSMNNSFTPAPMIMEIP 1721
P QQQP Q P P P PP P P QQP Q + P P P
Sbjct: 536 PLQQQQPPQPPPPPPPPPPSQPQPLQQPQPPQLQPPHQVPPQPQTQPPP 584
Score = 37.4 bits (85), Expect = 0.15
Identities = 34/105 (32%), Positives = 44/105 (41%), Gaps = 11/105 (10%)
Query: 1579 GNSSSQSSCSYGGLSSSSSLTQSSCVVTQQMASMGSSCS------MMQQSSVQPAANCSI 1632
G +S + + S SSSL + VV+ + +S+ S + QQ QP
Sbjct: 494 GTTSDWDAVNSQSESISSSLNEG--VVSYESSSINGRKSGVMLDPLQQQQPPQPPPPPPP 551
Query: 1633 KSPQSCVVERPPSNQQQQPPP--PPPQQPQPPP-PQPQPAPQPPP 1674
P + P Q QPP PP Q QPPP QPQP Q P
Sbjct: 552 PPPSQPQPLQQPQPPQLQPPHQVPPQPQTQPPPTQQPQPPTQAAP 596
Score = 33.9 bits (76), Expect = 1.6
Identities = 77/418 (18%), Positives = 150/418 (35%), Gaps = 69/418 (16%)
Query: 1297 EPEEEEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQPTREDVK-------------- 1342
+ +++EDA N + D ++E+D +E + + EE+PT ++
Sbjct: 709 QTKQQEDAVI----NVEDDEEEEEDNEVEIEVELDREEEPTEPIIEVPTSFSAQQIWVRD 764
Query: 1343 -EEPGVQESFLDANMQKSREKIKDKEETELDSEEEQPSHDTSVVSEQMA----------- 1390
EP + +F + + + E T + EE+ T++ Q++
Sbjct: 765 TSEPQKEPNFRNITHDYNATNGAEIELTLSEDEEDYYGSSTNLKDHQVSNTALLNTQTPI 824
Query: 1391 -GSEDDHEE-DSHTKEELIELKEEEEIPHSELDLETVQAVQSLTQEESSEHEGAYQ---D 1445
G+E + E D L K H + + ++ ++V + Q + +++ D
Sbjct: 825 YGTEHNSENTDFGDSGRLYYCK------HCDFNNKSARSVSTHYQRMHPYIKFSFRYILD 878
Query: 1446 CEETLAACQTLQSYTQADEDPQMSMVEDCHASEHNSPISSVQS--HPSQSVR----SVSS 1499
+ A + L+ Y + H EH+ +V + H R S +S
Sbjct: 879 PNDHSAVYRCLECYIDYTNFEDLQQ----HYGEHHPEAMNVLNFDHSDLIYRCRFCSYTS 934
Query: 1500 PNVPALESGYTQISPEQGSLSAPSMQNMETSPMMDVPSVSDHSQQVVDSGFSDLGSIEST 1559
PNV +L Y ++ P +A + + + S +++++S ++ +
Sbjct: 935 PNVRSLMPHYQRMHPTVKINNAMIFSSYVVEQQEGLNTESQTLREILNSAPKNMATSTPV 994
Query: 1560 TENYENPSSYDSTMGGSICGNSSSQSS-------------CSYGGLSSSSSLTQSSCVVT 1606
P++++ + +Q CS+ + S L
Sbjct: 995 ARGGGLPATFNKNTPKTFTPECENQKDPLVNTVVVYDCDVCSFASPNMHSVLVHYQKKHP 1054
Query: 1607 QQMASMGSSCSMMQQSSVQPAANCSIKSPQSCVVERPPSNQQQQPPPPPPQQPQPPPP 1664
++ AS M+ SV S S S V P S + PPP PQPPPP
Sbjct: 1055 EEKASYFRIQKTMRMVSVDRG---SALSQLSFEVGAPMSPKMSNMGSPPP--PQPPPP 1107
Score = 31.6 bits (70), Expect = 8.2
Identities = 23/88 (26%), Positives = 41/88 (46%), Gaps = 6/88 (6%)
Query: 1352 LDANMQKSREKIKDKEETELDSEEEQPSHDTSVVSEQMAGSEDDHEEDSHTKEEL-IELK 1410
LD + K R +I E+ S + + T + + EDD EE+ + E+ +EL
Sbjct: 685 LDLSPVKKRTRID-----EIASNLQSKINQTKQQEDAVINVEDDEEEEEDNEVEIEVELD 739
Query: 1411 EEEEIPHSELDLETVQAVQSLTQEESSE 1438
EEE +++ T + Q + ++SE
Sbjct: 740 REEEPTEPIIEVPTSFSAQQIWVRDTSE 767
>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
Length = 2817
Score = 83.6 bits (205), Expect = 2e-15
Identities = 193/946 (20%), Positives = 336/946 (35%), Gaps = 161/946 (17%)
Query: 834 KPEVMAPVSSTRLSKQVLPHDSLPANSQPSRRGRWGRKNRKTQERFGDKDSKLLLEETSS 893
+PE + +S++ L K++ D+L A + G + Q F D D E+ S+
Sbjct: 290 EPERPSILSASEL-KELDKFDNLDAEADEGWAGAQMEVDYTEQLNFSDDD-----EQGSN 343
Query: 894 APQEQYGECGEKSEATQEQYTESEEQLVASEEQPSQDGKPDLPKRRLSEGVEPWRGQLKK 953
+P+E E + S+A++ + E V++ + SQ +P + V +G
Sbjct: 344 SPKENNSE-DQGSKASENNENKKETDEVSNTKSSSQ-----IPAQPSVAKVPYGKGPSFN 397
Query: 954 SPEALKCRLTEGSERLPRRYSEGDRAVLRGF-------SESSEEEEEPESPRSSSPPILT 1006
L + L +++ DR + G + ++E+E + R I
Sbjct: 398 QERGTSSHLPPPPKLLAQQHPPPDRQAVPGRPGPFPSKQQVADEDEIWKQRRRQQSEISA 457
Query: 1007 KPTLKRKKPFLHRRRRVRKRKHHNSSVVTETISETTEVLDEPFEDSDSERPMPRLEPTFE 1066
RK+ RR +RK +E + LDE + + P E E
Sbjct: 458 AVERARKRREEEERRMEEQRK--------AACAEKLKRLDEKLGILEKQ---PSPEEIRE 506
Query: 1067 IDEEEEEEDENELFPREYFRRLSSQDVLRCQSSSKRKSKDEEEDEESDDADDTPILKPVS 1126
+ E+E E E EL + Q K + KD E +E +
Sbjct: 507 REREKEREREKELEKEQE------------QEREKEREKDRERQQEKEKE---------- 544
Query: 1127 LLRKRDVKNSPLEPDTSTPLKKKKGWPKGKSRKPIHWKKRPGRKPGFKLSREIMPVSTQA 1186
L K K +E + +K+ K K ++ K++ +
Sbjct: 545 -LEKEQEKQREMEKERKQEKEKELERQKEKEKELQKMKEQE-----------------KE 586
Query: 1187 CVIEPIVSIPKAGRKPKIQESEETVEPKEDMPLPEERKEEEEMQAEAEEAEEGEEEDAAS 1246
C +E + ++ EE +EP+E P K+E E EE +D+
Sbjct: 587 CELEK-----------EREKLEEKIEPREPNLEPMVEKQESENSCNKEEEPVFTRQDSNR 635
Query: 1247 SEVPAASPADSSNSPETETK-EPEVE----EEEEKPRVSEEQRQSEEEQQELEEPEPEEE 1301
SE A+P PE+ ++ P V ++ +K QRQ E+ +Q+ + + +++
Sbjct: 636 SE-KEATPVVHETEPESGSQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQ--QWQQQQQ 692
Query: 1302 EDAAAETAQNDDHDADDEDDGHLESTKKKELEEQPTREDVKEEPG--VQESFLDANMQKS 1359
+ +T + + H + + Q + +P + +S++D M
Sbjct: 693 QGVLPQTVPSQPSSSTVPPPPHRPLYQPMQPHPQHLAS-MGFDPRWLMMQSYMDPRMMSG 751
Query: 1360 REK----------IKDKEETELDSEEEQPSHDTSVVSEQMAGSEDDHEEDSHTKEELIEL 1409
R I K D E P+ S E +A S DH + + E L
Sbjct: 752 RPAMDIPPIHPGMIPPKPLMRRDQMEGSPNSSESF--EHIARSARDH---AISLSEPRML 806
Query: 1410 KEEEEIPHSELDLETVQAVQSLTQEESSEHEGAYQDCEETLAACQTLQSYTQADEDPQMS 1469
+ PH+E T T+E A D E+ AA + Q + P+
Sbjct: 807 WGSDPYPHAEPQQATTPKA---TEEPEDVRSEAALDQEQITAAYSV--EHNQLEAHPKAD 861
Query: 1470 MVEDCHASEHNSPISSVQSHPSQSVRSVSSPNVPALESGYTQISPEQGSLSAPSMQNM-- 1527
+ + S + VQ S+SV V + A +P+Q +LSAP + +
Sbjct: 862 FIRE-------SSEAQVQKFLSRSVEDVRPHHTDANNQSACFEAPDQKTLSAPQEERISA 914
Query: 1528 ---ETSPMMDVPSVSDHSQQVVDSGFSDLGSIESTT-------ENYENPSSYDSTMGGSI 1577
+ S V S+H+Q+ + I T E E P G
Sbjct: 915 VESQPSRKRSVSHGSNHTQKPDEQRSEPSAGIPKVTSRCIDSKEPIERPEEKPKKEGFIR 974
Query: 1578 CGNS-------SSQSSCSYGGLSSSSS--------LTQSSCVVTQQMASMGSSCSMMQQS 1622
S+S +G SS+ + +S + + M ++
Sbjct: 975 SSEGPKPEKVYKSKSETRWGPRPSSNRREEVNDRPVRRSGPIKKPVLRDMKEEREQRKEK 1034
Query: 1623 SVQPAANCSIKSPQSCVVERPPSNQQQQ--PPPPPPQQPQPPPPQPQPAPQPPPPQQQPQ 1680
+ A + K VV +P +++ PPPPPPQ P P PQ P P P ++ P
Sbjct: 1035 EGEKAEKVTEK-----VVVKPEKTEKKDLPPPPPPPQPPAPIQPQSVPPPIQPEAEKFPS 1089
Query: 1681 -------QQPQPQPQQPPPPPPPQQQPPLSQCSMNNSFTPAPMIME 1719
Q+P ++P P Q P + ++N AP++ E
Sbjct: 1090 TETATLAQKPSQDTEKPLEPVSTVQVEPAVK-TVNQQTMAAPVVKE 1134
Score = 75.1 bits (183), Expect = 6e-13
Identities = 115/526 (21%), Positives = 217/526 (41%), Gaps = 59/526 (11%)
Query: 1037 TISETTEVL----DEPFEDSDSERP-------MPRLEPTFEIDEEEEEEDENELFPREYF 1085
++SET + L P S+ ERP + L+ +D E +E +Y
Sbjct: 270 SLSETNKGLRGRGPPPSWASEPERPSILSASELKELDKFDNLDAEADEGWAGAQMEVDYT 329
Query: 1086 RRLS-SQDVLRCQSSSKRKSKDEEEDEESDDADDTPILKPVSLLRKRDVKNSPLEPDTST 1144
+L+ S D + +S K + +++ + S++ ++ VS + K+S P +
Sbjct: 330 EQLNFSDDDEQGSNSPKENNSEDQGSKASENNENKKETDEVS-----NTKSSSQIP--AQ 382
Query: 1145 PLKKKKGWPKGKSRKPIHWKKRPGRKPGFKLSREIMPVSTQACVIEPIVSIPKAGRKPKI 1204
P K + KG S P L+++ P QA P G P
Sbjct: 383 PSVAKVPYGKGPSFNQERGTSSHLPPPPKLLAQQHPPPDRQAVPGRP-------GPFPSK 435
Query: 1205 QESEETVEPKEDMPLPEERKEEEEMQAEAEEAEEG-EEEDAASSEVPAASPADSSNSPET 1263
Q+ + ED + R+++ E+ A E A + EEE+ E A+ A+ +
Sbjct: 436 QQVAD-----EDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDE 490
Query: 1264 ET----KEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDE 1319
+ K+P EE E+ R E +R+ E E+++ +E E E E+D + + + + + E
Sbjct: 491 KLGILEKQPSPEEIREREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQE 550
Query: 1320 DDGHLESTKKKELEEQPTREDVKEEP--GVQESFLDANMQKSREKIKDKEETELDSEEEQ 1377
+E +K+E E++ R+ KE+ ++E + ++K REK+++K E +
Sbjct: 551 KQREMEKERKQEKEKELERQKEKEKELQKMKEQEKECELEKEREKLEEK------IEPRE 604
Query: 1378 PSHDTSVVSEQMAGSEDDHEEDSHTKEELIELKEEEEIPHSELDLETVQAVQSLTQEESS 1437
P+ + V ++ S + EE T+++ ++E E + E S +Q +
Sbjct: 605 PNLEPMVEKQESENSCNKEEEPVFTRQDSNRSEKEATPVVHETEPE------SGSQPRPA 658
Query: 1438 EHEGAYQDCEETL----AACQTLQSYTQADEDPQMSMVEDCHASEHNSPISSVQSHPSQS 1493
G ++ +++L Q Q + Q ++ S+ +S S+V P +
Sbjct: 659 VLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQQQQQGVLPQTVPSQPSS--STVPPPPHRP 716
Query: 1494 VRSVSSPNVPALES-GYTQISPEQGSLSAPSMQNMETSPMMDVPSV 1538
+ P+ L S G+ S P M M P MD+P +
Sbjct: 717 LYQPMQPHPQHLASMGFDPRWLMMQSYMDPRM--MSGRPAMDIPPI 760
Score = 55.5 bits (132), Expect = 5e-07
Identities = 151/820 (18%), Positives = 308/820 (37%), Gaps = 95/820 (11%)
Query: 949 GQLKKSPEALKCRLTEGSERLPRRYSEGDRAVLRGFSESSEEEEEPESPRSSSPPILTKP 1008
G L++ E+ + E +P+R + RG SE+ + E ES +S L+K
Sbjct: 1234 GPLRQREESETRSESSDFEVVPKRRRQ------RG-SETDTDSEIHES--ASDKDSLSKG 1284
Query: 1009 TLKRKKPFLHRRRRVRKRKHHNSSVVTETISETTEVLDEPF-EDSDSERP--MPRLEPTF 1065
L +++ ++ V K H+S + +L++P+ D D +P +P+ EPT
Sbjct: 1285 KLPKREERPENKKPV---KPHSSFKPDNHVRIDNRLLEKPYVRDDDKAKPGFLPKGEPTR 1341
Query: 1066 EIDEEEEEEDENELFPREYFRRLSSQDVLRCQSSSKRKSK-DEEEDEESDDADDTPILKP 1124
+ R + R + R+S+ + ED E + I P
Sbjct: 1342 RGRGGTFRRGGRDPGGRPSRPSTLRRPAYRDNQWNPRQSEVPKPEDGEPPRRHEQFI--P 1399
Query: 1125 VSLLRKRDVKNSPLEPDTSTPLKKKKGWPKGKSRKPIHWKKRPGRKPGFKLSREIMPVST 1184
++ ++ +P P +++ P + KP +++ R+ K S E++ V T
Sbjct: 1400 IAADKRPPKFERKFDPARERPRRQRPTRPP-RQDKPPRFRRLREREAASK-SNEVVAVPT 1457
Query: 1185 QACVI----EPIVSIP--KAGRKPKIQESEETVEPKEDMPLPEERKEEEEMQAEAEEAEE 1238
V EP+ ++ + P + + + E+ E + E + E
Sbjct: 1458 NGTVNNVAQEPVNTLGDISGNKTPDLSNQNSSDQANEEWETASESSDFNERR------ER 1511
Query: 1239 GEEEDAASSEVPAASPADSSNSPETETKEPEVEEEEEKPRVSEEQRQSEEEQ-QELEEPE 1297
E+++A + ++ P+ E + + R + + + P
Sbjct: 1512 DEKKNADLNAQTVVKVGENVLPPKREIAKRSFSSQRPVDRQNRRGNNGPPKSGRNFSGPR 1571
Query: 1298 PEEEEDAAAETAQN---DDHDADDEDDGHLESTKKKELEEQPT---REDVKEEPGVQESF 1351
E +++ + DD A + + E P +++ K+ G +
Sbjct: 1572 NERRSGPPSKSGKRGPFDDQPAGTTGVDLINGSSAHHQEGVPNGTGQKNSKDSTGKKRED 1631
Query: 1352 LDANMQKSREKIKDKEETELDSE------EEQPSHDTSVVSEQMAGSEDDHEEDSHTKEE 1405
+K +EK+ + +L++ ++ P + +V+ + + DD + +K++
Sbjct: 1632 PKPGPKKPKEKVDALSQFDLNNYASVVIIDDHP--EVTVIEDPQSNLNDDGFTEVVSKKQ 1689
Query: 1406 LIELKEEEEIPHSELDLETVQAVQSLTQEESSEHEGAYQDCEETLAACQTLQSYTQADED 1465
L++EE E Q +Q ++ ++E +G Q + +
Sbjct: 1690 QKRLQDEERRKKEE------QVIQVWNKKNANE-KGRSQTSKLPPRFAKK---------- 1732
Query: 1466 PQMSMVEDCHASEHNSPISSVQSHPSQSVRSVSSPNVPALESGYTQISPEQGSLSAPSMQ 1525
Q + ++ +S P++S PS S +S + P + ++P S SAP
Sbjct: 1733 -QATGIQQAQSSASVPPLASAPLPPSTSASVPASTSAPLPAT----LTPVPASTSAP--- 1784
Query: 1526 NMETSPMMDVPSVSDHSQQVVDSGFSDLGSIESTTENYENPSSYDSTMGGSICGNSSSQS 1585
+ S + P ++ S V S + + + S + + ST +I +S+ S
Sbjct: 1785 -VPASTL--APVLASTSAPVPASPLAPVSASASVSASVPA-----STSAAAITSSSAPAS 1836
Query: 1586 SCSYGGLSSSSSLTQSSCVVTQQMASMGSSCSMMQQSSVQPAANCSIKSPQSCVVERP-- 1643
+ + + +S S S ++ + +S ++ S+ PA S SP + V+ P
Sbjct: 1837 APAPTPILASVSTPASVTILASASIPILAS-ALASTSAPTPAPAAS--SPAAPVITAPTI 1893
Query: 1644 PSNQQQQPPPPPPQQPQPPPPQPQPA----PQPPPPQQ------QPQQQPQPQPQQPPPP 1693
P++ P P P P P P P PP P Q +P Q P Q
Sbjct: 1894 PASAPTASVPLAPASASAPAPAPTPVSAPNPAPPAPAQTQAQTHKPVQNPLQTTSQSSKQ 1953
Query: 1694 PPPQQQPPLSQCSMNNSFTPAPMIMEIPESGSTGNISIYE 1733
PPP + P +Q + + ++ P+S T +++
Sbjct: 1954 PPPSIRLPSAQTPNGTDYVASGKSIQTPQSHGTLTAELWD 1993
Score = 49.7 bits (117), Expect = 3e-05
Identities = 228/1186 (19%), Positives = 392/1186 (33%), Gaps = 170/1186 (14%)
Query: 792 EEAEEGENEEPQCQERELEISVGKSVSHENKEQDSYSVESEKKPEVMAPVSSTRLSKQVL 851
EE E+ +E QE +I+ SV H E + + E +R + V
Sbjct: 827 EEPEDVRSEAALDQE---QITAAYSVEHNQLEAHPKADFIRESSEAQVQKFLSRSVEDVR 883
Query: 852 PHDSLPANSQPSRRGRWGRKNRKT--QERFGDKDSKLLLEETSS-------APQEQYGEC 902
PH + AN+Q + +K +ER +S+ + + S P EQ E
Sbjct: 884 PHHT-DANNQSACFEAPDQKTLSAPQEERISAVESQPSRKRSVSHGSNHTQKPDEQRSEP 942
Query: 903 GEKSEATQEQYTESEEQLVASEEQPSQDGKPDLPKRRLSEGVEPWRGQLKKS-----PEA 957
+ +S+E + EE+P ++G R SEG +P + KS P
Sbjct: 943 SAGIPKVTSRCIDSKEPIERPEEKPKKEG-----FIRSSEGPKPEKVYKSKSETRWGPRP 997
Query: 958 LKCRLTEGSERLPRRYSEGDRAVLRGFSESSEEEEEPESPRSS--SPPILTKPTLKRKKP 1015
R E ++R RR + VLR E E+ +E E ++ + ++ KP KK
Sbjct: 998 SSNRREEVNDRPVRRSGPIKKPVLRDMKEEREQRKEKEGEKAEKVTEKVVVKPEKTEKKD 1057
Query: 1016 FLHRRRRVRKRKHHNSSVVTETI---------SETTEVLDEPFEDSDSERPMPRLEPTFE 1066
+ V I +ET + +P D+E+P LEP
Sbjct: 1058 LPPPPPPPQPPAPIQPQSVPPPIQPEAEKFPSTETATLAQKP--SQDTEKP---LEPVST 1112
Query: 1067 IDEEEEEEDENELFPREYFRRLSSQDVLRCQSSSKRKSKDEEEDEESDDADDTPILKPVS 1126
+ E + N Q + EE+ E + D I +P
Sbjct: 1113 VQVEPAVKTVN-------------------QQTMAAPVVKEEKQPEKVISKDLVIERPRP 1153
Query: 1127 LLRKRDVKNSPLEPDTSTPLKKKKGW-----PKGKSRKPIHWKKRPGR-------KPGFK 1174
R K S L P T +++ W +G+ R + + R R + G
Sbjct: 1154 DSRPAVKKESTLPPRTYWKEARERDWFPDQGYRGRGRGEYYSRGRSYRGSYGGRGRGGRG 1213
Query: 1175 LSREIMPVSTQACVIEPIVSIPKAGRKPKIQESEETVEPKEDMPLPEERKEE-EEMQAEA 1233
+R+ E I S P R +ESE E + +P+ R++ E ++
Sbjct: 1214 HTRDYPQYRDNKPRAEHIPSGPLRQR----EESETRSESSDFEVVPKRRRQRGSETDTDS 1269
Query: 1234 EEAEEGEEEDAAS-SEVPAASPADSSNSPETETKEPEVEEEEEKP--------RVSEEQR 1284
E E ++D+ S ++P E K+P KP R+ E+
Sbjct: 1270 EIHESASDKDSLSKGKLP-------KREERPENKKPVKPHSSFKPDNHVRIDNRLLEKPY 1322
Query: 1285 QSEEEQQE---LEEPEPEEEEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQPTREDV 1341
++++ + L + EP D L ++ + P + +V
Sbjct: 1323 VRDDDKAKPGFLPKGEPTRRGRGGTFRRGGRDPGGRPSRPSTLRRPAYRDNQWNPRQSEV 1382
Query: 1342 -KEEPGVQESFLDANMQKSREKIKDKEETELDSEEEQPSHDTSV-------------VSE 1387
K E G + + + +K K E + D E+P + E
Sbjct: 1383 PKPEDGEPPRRHEQFIPIAADKRPPKFERKFDPARERPRRQRPTRPPRQDKPPRFRRLRE 1442
Query: 1388 QMAGSEDDHEEDSHTKEELIELKEEEEIPHSELDLETVQAVQSLTQEESSEHEGAYQDCE 1447
+ A S+ + T + + +E P + L + L+ + SS+ +
Sbjct: 1443 REAASKSNEVVAVPTNGTVNNVAQE---PVNTLGDISGNKTPDLSNQNSSDQA---NEEW 1496
Query: 1448 ETLAACQTLQSYTQADEDPQMSMVEDCHASEHNS---PISSVQSHPSQSVRSVSSPNVPA 1504
ET + + DE + + P + S R V N
Sbjct: 1497 ETASESSDFNERRERDEKKNADLNAQTVVKVGENVLPPKREIAKRSFSSQRPVDRQNRRG 1556
Query: 1505 ----LESGYTQISPEQGSLSAPSMQNMETSPMMDVPS----------VSDHSQQVVDSGF 1550
+SG P S P ++ + P D P+ S H Q+ V +G
Sbjct: 1557 NNGPPKSGRNFSGPRNERRSGPPSKSGKRGPFDDQPAGTTGVDLINGSSAHHQEGVPNGT 1616
Query: 1551 SDLGSIESTTENYENP--------------SSYDSTMGGS---------ICGNSSSQSSC 1587
S +ST + E+P S +D S + QS+
Sbjct: 1617 GQKNSKDSTGKKREDPKPGPKKPKEKVDALSQFDLNNYASVVIIDDHPEVTVIEDPQSNL 1676
Query: 1588 SYGGLSSSSSLTQSSCVVTQQMASMGSSCSMM--QQSSVQPAANCSIKSPQSCVVERPPS 1645
+ G + S Q + ++ + ++++ + + + K P ++
Sbjct: 1677 NDDGFTEVVSKKQQKRLQDEERRKKEEQVIQVWNKKNANEKGRSQTSKLPPRFAKKQATG 1736
Query: 1646 NQQQQPPPPPPQQPQPPPPQPQPAPQPPPPQQQPQQQPQPQPQQPPPPPPPQQQPPLSQC 1705
QQ Q P P P A P P P P P P+
Sbjct: 1737 IQQAQSSASVPPLASAPLPPSTSASVPASTSAPLPATLTPVPASTSAPVPASTLAPV--- 1793
Query: 1706 SMNNSFTPAPMIMEIPESGSTGNISIYERIPGDFGAGSYSQPSATFSLAKLQQLTNTIMD 1765
+ ++ P P P S S S+ +P A + + SA S + ++
Sbjct: 1794 -LASTSAPVPASPLAPVSASA---SVSASVPASTSAAAITSSSAPASAPAPTPILASVST 1849
Query: 1766 PHAMPYSHS---PAVTSYATSVSLSNTGLAQLAPSHPLAGTPQAQATM-TPPPNLASTTM 1821
P ++ S P + S S S A +P+ P+ P A+ T LA +
Sbjct: 1850 PASVTILASASIPILASALASTSAPTPAPAASSPAAPVITAPTIPASAPTASVPLAPASA 1909
Query: 1822 NLTSPLLQCNMSATNIGIPHTQRLQGQ--MPVKGHISIRSKSAPLP 1865
+ +P +SA N P + Q Q PV+ + S+S+ P
Sbjct: 1910 SAPAP-APTPVSAPNPAPPAPAQTQAQTHKPVQNPLQTTSQSSKQP 1954
Score = 42.7 bits (99), Expect = 0.004
Identities = 112/607 (18%), Positives = 216/607 (35%), Gaps = 83/607 (13%)
Query: 786 VSEEEEEEAEEGENEEPQCQERELEISVGKSVSHENKEQDSYSVESEKKPEV---MAPVS 842
+ E E E+ E E E + QE+E E K + +++ E EK+ E+
Sbjct: 504 IREREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQEK 563
Query: 843 STRLSKQVLPHDSLPANSQPSRRGRWGRKNRKTQERFGDKDSKLLLEETSSAPQEQYGEC 902
L +Q L + + ++ K +E+ ++ L E QE C
Sbjct: 564 EKELERQKEKEKELQKMKEQEKECELEKEREKLEEKIEPREPNL---EPMVEKQESENSC 620
Query: 903 GEKSEA--TQEQYTESEEQL--VASEEQPSQDGKPDLPKRRLSEGVEPWRGQLKKSPEAL 958
++ E T++ SE++ V E +P +P G K+ ++L
Sbjct: 621 NKEEEPVFTRQDSNRSEKEATPVVHETEPESGSQP---------RPAVLSGYFKQFQKSL 671
Query: 959 KCRLTEGSERLPRRYSEGDRAVLRGFSESSEEEEEPESPRSSS-PPILTKPTLKRKKPFL 1017
R E++ ++ + + + + P P SS+ PP +P + +P
Sbjct: 672 PPRFQRQQEQMKQQQWQQQQ------QQGVLPQTVPSQPSSSTVPPPPHRPLYQPMQP-- 723
Query: 1018 HRRRRVRKRKHHNSSVVTETISETTEVLDEPFEDSDSERP-MPRLEPTFEIDEEEEEEDE 1076
+ + ++ ++ + + P D P M +P D+ E +
Sbjct: 724 -HPQHLASMGFDPRWLMMQSYMDPRMMSGRPAMDIPPIHPGMIPPKPLMRRDQMEGSPNS 782
Query: 1077 NELF------PREYFRRLSSQDVL---------RCQSSSKRKSKDEEEDEESDDADDTPI 1121
+E F R++ LS +L Q ++ K+ +E ED S+ A D
Sbjct: 783 SESFEHIARSARDHAISLSEPRMLWGSDPYPHAEPQQATTPKATEEPEDVRSEAALDQEQ 842
Query: 1122 LKPVSLLRKRDVKNSPLEPDTSTPLKKKKGWPKGKSRKPIHWKKRPGRKPGFKLSREIMP 1181
+ + ++ P K + + S + +K + ++ P
Sbjct: 843 ITAAYSVEHNQLEAHP-----------KADFIRESSEAQV-------QKFLSRSVEDVRP 884
Query: 1182 VSTQACVIEPIVSIPKAGRKPKIQESEETVEPKEDMPLPEERKEEEEMQAEAEEAEEGEE 1241
T A P +K EE + E P ++ + + ++
Sbjct: 885 HHTDANNQSACFEAP--DQKTLSAPQEERISAVESQP--------SRKRSVSHGSNHTQK 934
Query: 1242 EDAASSEVPAASPADSSNSPETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEE 1301
D SE A P +S ++KEP +E EEKP+ R S E P+PE+
Sbjct: 935 PDEQRSEPSAGIPKVTSRC--IDSKEP-IERPEEKPKKEGFIRSS-------EGPKPEKV 984
Query: 1302 EDAAAETAQNDDHDADDEDDGHLESTKKKELEEQPTREDVKEEPGVQESFLDANMQKSRE 1361
+ +ET ++ ++ + ++ ++P D+KEE ++ +K E
Sbjct: 985 YKSKSETRWGPRPSSNRREEVNDRPVRRSGPIKKPVLRDMKEEREQRKEKEGEKAEKVTE 1044
Query: 1362 KIKDKEE 1368
K+ K E
Sbjct: 1045 KVVVKPE 1051
Score = 41.6 bits (96), Expect = 0.008
Identities = 157/774 (20%), Positives = 263/774 (33%), Gaps = 136/774 (17%)
Query: 1233 AEEAEEGEEE--DAASSEVPAASPADSSNSPETETKEPEVEEEEEKPRVSEEQRQSEEEQ 1290
+E A+ G+E + + + +PA + N E E P +SE+ E
Sbjct: 2036 SEGAKNGQESGLEIGTDTIQFGAPASNGN------------ENEVVPVLSEKSADKIPEP 2083
Query: 1291 QELEEPEPEEEEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQPTREDVKEEPGVQES 1350
+E + +P G +++ K +L +E G + S
Sbjct: 2084 KEQRQKQPRA---------------------GPIKAQKLPDLSPVENKEHKPGPIGKERS 2122
Query: 1351 FLDANMQKSREKIKDKEETELDSEEEQPSHDTSVVSEQMAGSEDDHEEDSHTKEELIELK 1410
K+KD ++ E + +E+ PS T ++ + E + T E+
Sbjct: 2123 L-------KNRKVKDAQQVEPEGQEK-PSPATVRSTDPVTTKETKAVSEMST-----EIG 2169
Query: 1411 EEEEIPHSELDLETVQAVQSLTQEESSEHEGAYQD---CEETLAACQTLQSYTQADEDPQ 1467
+ +E ++V T SS + E+TL L + P+
Sbjct: 2170 TMISVSSAEYGTNAKESVTDYTTPSSSLPNTVATNNTKMEDTLVNNVPLPNTLPL---PK 2226
Query: 1468 MSMVEDCHASEHNSPISSVQSHPSQSVRSV--SSPNVPALESGYTQISPE-----QGSLS 1520
++ + P + + +S R +SPNV S T +P S S
Sbjct: 2227 RETIQQSSSLTSVPPTTFSLTFKMESARKAWENSPNVREKGSPVTSTAPPIATGVSSSAS 2286
Query: 1521 APSMQNMETSPMMDVPSVSDHSQQVVDSGFSDLGSIESTTENYENPSSYDSTMGGSICGN 1580
PS N + +P + S S S G+ +++ + ++ ++ D +IC
Sbjct: 2287 GPSTANYNSFSSASMPQIPVASVTPTAS-LSGAGTYTTSSLSTKSTTTSDPP---NICKV 2342
Query: 1581 SSSQSSCSYGGLSSSSSLTQSSCVVT-----QQMASMGSSCSMMQQSSVQPAANCSIKSP 1635
Q S L S+S +Q SC+ + QQ + S S Q + +
Sbjct: 2343 KPQQLQTS--SLPSASHFSQLSCMPSLIAQQQQNPQVYVSQSAAAQIPAFYMDTSHLFNT 2400
Query: 1636 QSCVVERPPSNQQQQPPPPPPQQPQPPPPQPQPAPQPPPPQQQP-QQQPQPQPQQPPPPP 1694
Q + PPS QQ Q QP QP Q P P P Q Q Q Q P
Sbjct: 2401 QHARLA-PPSLAQQ-------QGFQPGLSQPTSVQQIPIPIYAPLQGQHQAQLSLGAGPA 2452
Query: 1695 PPQQQPPLSQCSMNNSFTPAPMIMEIPESGSTGNISIYERIPGDFGAGSYSQPSATFSLA 1754
Q Q S S + P M+ S S ++ + +F + + + S
Sbjct: 2453 VSQAQELFS--SSLQPYRSQPAFMQ--SSLSQPSVVLSGTAIHNFPTVQHQELAKAQSGL 2508
Query: 1755 KLQQLTNTIMDPHAMPYSHSPAVTSYATSVSLSNTGLAQLAPSHPLAGTPQAQATMTPPP 1814
QQ +NT P + Y H S G +QL +H L QA+A +T
Sbjct: 2509 AFQQTSNT--QPIPILYEHQLG--------QASGLGGSQLIDTHLL----QARANLTQAS 2554
Query: 1815 NL-------------------ASTTMNLTSPLLQCNMSATNIGI---PHTQRLQGQMPVK 1852
NL S +T PL +S N G P Q P
Sbjct: 2555 NLYSGQVQQPGQTNFYNTAQSPSALQQVTVPLPASQLSLPNFGSTGQPLIALPQTLQPPL 2614
Query: 1853 GHISIRSKSAPLPSAAAHQQQLYGRSPS----AVAMQAGPRALAVQRGMNMGVNLMP--- 1905
H + ++++ L A Q G P+ ++ G + + G+++ P
Sbjct: 2615 QHTTPQAQAQSLSRPAQVSQPFRGLIPAGTQHSMIATTGKMSEMELKAFGSGIDIKPGTP 2674
Query: 1906 -------TPAYNVNSMNMNTLNAMNSYRMTQPMMNSSYHSNPAYMNQTAQYPMQ 1952
TP + + N+ +S +M + + S PA + T +P Q
Sbjct: 2675 PIAGRSTTPTSSPFRATSTSPNSQSS-KMNSIVYQKQFQSAPATVRMTQPFPTQ 2727
Score = 37.0 bits (84), Expect = 0.19
Identities = 102/575 (17%), Positives = 185/575 (32%), Gaps = 85/575 (14%)
Query: 1221 EERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSNSPETETKEPEVEEEEEKPRVS 1280
+E + + + AEA+E G A EV + S+ E + P+ E++ +
Sbjct: 303 KELDKFDNLDAEADEGWAG-----AQMEVDYTEQLNFSDDDEQGSNSPKENNSEDQGSKA 357
Query: 1281 EEQRQSEEEQQELEEPE-----PEEEEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQ 1335
E ++++E E+ + P + A + + + HL K ++
Sbjct: 358 SENNENKKETDEVSNTKSSSQIPAQPSVAKVPYGKGPSFNQERGTSSHLPPPPKLLAQQH 417
Query: 1336 PTREDVKEEPGVQESFLDANMQKSREKIKDKEETELDSEEEQPSHDTSVVSEQMAGSEDD 1395
P D + PG F S++++ D++E +Q +V + E++
Sbjct: 418 PP-PDRQAVPGRPGPF------PSKQQVADEDEIWKQRRRQQSEISAAVERARKRREEEE 470
Query: 1396 HEEDSHTK----EELIELKEE----------EEIPHSELDLETVQAVQSLTQEESSEHEG 1441
+ K E+L L E+ EEI E + E + + L +E+ E E
Sbjct: 471 RRMEEQRKAACAEKLKRLDEKLGILEKQPSPEEIREREREKER-EREKELEKEQEQERE- 528
Query: 1442 AYQDCEETLAACQTLQSYTQADEDPQMSMVEDCHASEHNSPISSVQSHPSQSVRSVSSPN 1501
++ E+ Q + + +++ Q M ++ E + + + +
Sbjct: 529 --KEREKDRERQQEKEKELEKEQEKQREMEKE-RKQEKEKELERQKEKEKELQKMKEQEK 585
Query: 1502 VPALESGYTQISPEQGSLSAPSMQNMETSPMMDVPSVSDHSQQVVDSGFSDLGSIESTTE 1561
LE ++ + P N+E PM++ + + + F+ S S E
Sbjct: 586 ECELEKEREKLEEK----IEPREPNLE--PMVEKQESENSCNKEEEPVFTRQDSNRSEKE 639
Query: 1562 NYENPSSYDSTMGGSICGNSSSQSSCSYGGLSSSSSLTQSSCVVTQQMASMGSSCSMMQQ 1621
+ G S G + QQ QQ
Sbjct: 640 ATPVVHETEPESG-------SQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQQQQ 692
Query: 1622 SSVQPAANCSIKSPQSCVVERPPSNQQQQPPPPPPQQPQPPPPQPQPAP------QPPPP 1675
V P + PS PPPP +P P QP P P
Sbjct: 693 QGVLP--------------QTVPSQPSSSTVPPPPHRPLYQPMQPHPQHLASMGFDPRWL 738
Query: 1676 QQQPQQQPQPQPQQPPPPPPPQQQPPLSQCSMNNSFTPAPMIMEIPESGSTGNISIYERI 1735
Q P+ +P PP P P++ GS + +E I
Sbjct: 739 MMQSYMDPRMMSGRPAMDIPPIHP---------GMIPPKPLMRRDQMEGSPNSSESFEHI 789
Query: 1736 PGDFGAGSYSQPSATFSLAKLQQLTNTIMDPHAMP 1770
+ S SL++ + L + PHA P
Sbjct: 790 -------ARSARDHAISLSEPRMLWGSDPYPHAEP 817
Score = 36.2 bits (82), Expect = 0.33
Identities = 122/672 (18%), Positives = 237/672 (35%), Gaps = 112/672 (16%)
Query: 784 SVVSEEEEEEAEEGENEEPQCQE----RELEISV------------GKSVSHENKEQDSY 827
S++S E +E ++ +N + + E ++E+ G + EN +D
Sbjct: 295 SILSASELKELDKFDNLDAEADEGWAGAQMEVDYTEQLNFSDDDEQGSNSPKENNSEDQG 354
Query: 828 SVESE--KKPEVMAPVSSTRLSKQVLPHDSLPANSQPSRRGRWGRKNRKTQERFGDKDSK 885
S SE + + VS+T+ S Q+ S+ P +G + R T K
Sbjct: 355 SKASENNENKKETDEVSNTKSSSQIPAQPSVA--KVPYGKGPSFNQERGTSSHL-PPPPK 411
Query: 886 LLLEETSSAPQEQYGECGEKSEATQEQYTESEEQLVASEEQPSQDGKPDLPKRRLSEGVE 945
LL ++ P ++ G +Q E+++ + + + + R E
Sbjct: 412 LLAQQ--HPPPDRQAVPGRPGPFPSKQQVADEDEIWKQRRRQQSEISAAVERARKRREEE 469
Query: 946 PWRGQLKKSP---EALKCRLTE---------GSERLPRRYSEGDRAVLRGFSESSEEEEE 993
R + ++ E LK RL E E + R E +R + + E+E E
Sbjct: 470 ERRMEEQRKAACAEKLK-RLDEKLGILEKQPSPEEIREREREKEREREKELEKEQEQERE 528
Query: 994 PESPRSSSPPILTKPTLKRKKPFLHRRRRVRKRKHHNSSVVTETISETTEVLDEPFEDSD 1053
E K ++ + + + K + + E E + L+ E
Sbjct: 529 KERE-------------KDRERQQEKEKELEKEQEKQREMEKERKQEKEKELERQKEKEK 575
Query: 1054 SERPMPRLEPTFEIDEEEEEEDENELFPREYFRRLSSQDVLRCQSSSKRKSKDEE----- 1108
+ M E E+ E+E E+ E ++ PRE + + ++ Q S +K+EE
Sbjct: 576 ELQKMKEQEKECEL-EKEREKLEEKIEPRE----PNLEPMVEKQESENSCNKEEEPVFTR 630
Query: 1109 EDEESDDADDTPIL-----------KPVSL--LRKRDVKNSPLEPDTSTPLKKKKGW--- 1152
+D + + TP++ +P L K+ K+ P K++ W
Sbjct: 631 QDSNRSEKEATPVVHETEPESGSQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQQ 690
Query: 1153 ------PKGKSRKPIHWKKRPGRKPGFKLSREIMPVSTQACVIEPIVSIPKAGRKPKIQE 1206
P+ +P P + P + +P + ++ P++
Sbjct: 691 QQQGVLPQTVPSQPSSSTVPPPPHRPLYQPMQPHPQHLASMGFDPRWLMMQSYMDPRMMS 750
Query: 1207 SEET-----VEPKEDMPLPEERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPA---DSS 1258
+ P P P R+++ E + E+ E A + + P S
Sbjct: 751 GRPAMDIPPIHPGMIPPKPLMRRDQMEGSPNSSESFEHIARSARDHAISLSEPRMLWGSD 810
Query: 1259 NSPETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADD 1318
P E P+ + + +EE + E ++E+ AA + +++ +A
Sbjct: 811 PYPHAE------------PQQATTPKATEEPEDVRSEAALDQEQITAAYSVEHNQLEAHP 858
Query: 1319 EDDGHLESTKKKELEEQPTREDVKEEPGVQESFLDANMQKS------REKIKDKEETELD 1372
+ D ES+ E Q + + V+ DAN Q + ++ + +E +
Sbjct: 859 KADFIRESS-----EAQVQKFLSRSVEDVRPHHTDANNQSACFEAPDQKTLSAPQEERIS 913
Query: 1373 SEEEQPSHDTSV 1384
+ E QPS SV
Sbjct: 914 AVESQPSRKRSV 925
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 83.2 bits (204), Expect = 2e-15
Identities = 41/103 (39%), Positives = 55/103 (53%), Gaps = 10/103 (9%)
Query: 209 CSFCLGTKEQNREKKPEELISCADCGNSGHPSCLKFSPELTVRVKALRWQCIECKTCSSC 268
C+ C G E +L C CG+ H +CL + LT R +A WQC ECK C +C
Sbjct: 229 CAVCEGPGELC------DLFFCTSCGHHYHGACLDTA--LTARKRA-GWQCPECKVCQAC 279
Query: 269 RDQGKNADNMLFCDSCDRGFHMECCDPPLTRMPKGMWICQICR 311
R G N ML C++CD+G+H C PP+ +P W C+ CR
Sbjct: 280 RKPG-NDSKMLVCETCDKGYHTFCLKPPMEELPAHSWKCKACR 321
Score = 75.1 bits (183), Expect = 6e-13
Identities = 31/84 (36%), Positives = 44/84 (52%), Gaps = 3/84 (3%)
Query: 227 LISCADCGNSGHPSCLKFSPELTVRVKALRWQCIECKTCSSCRDQGKNADNMLFCDSCDR 286
L++C+ C HP C+ + +K W+C+EC C C Q + +L CD CD
Sbjct: 1394 LLACSQCSQCYHPYCVNSKITKVMLLKG--WRCVECIVCEVC-GQASDPSRLLLCDDCDI 1450
Query: 287 GFHMECCDPPLTRMPKGMWICQIC 310
+H C DPPL +PKG W C+ C
Sbjct: 1451 SYHTYCLDPPLLTVPKGGWKCKWC 1474
Score = 61.6 bits (148), Expect = 7e-09
Identities = 125/563 (22%), Positives = 200/563 (35%), Gaps = 118/563 (20%)
Query: 1387 EQMAGSEDDHEEDSHTKEELIELKEEEEIPHSELDLETVQAVQSLTQEESSEHEGAYQDC 1446
+Q+ + ++ +++ +L++++++ +L + Q Q L Q++ + + Q
Sbjct: 3898 QQLQQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQ--QQLQQQQQQQLQQQQQQL 3955
Query: 1447 EETLAACQTLQSYTQADEDPQMSMVEDCHA-----SEHNSPISSVQSHPSQSVRSVSSPN 1501
++ Q Q + Q + QM ++ + ++ P++ ++ SSP
Sbjct: 3956 QQQQQ--QQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQVALGPGMPAKPLQHFSSPG 4013
Query: 1502 V----------------PALESGYTQ-ISPEQGSLSA--PSMQNMETSPMMDVPSVSDHS 1542
PA+ S T+ S QG A + ++M T P PS+S S
Sbjct: 4014 ALGPTLLLTGKEQNTVDPAVSSEATEGPSTHQGGPLAIGTTPESMATEPGEVKPSLSGDS 4073
Query: 1543 QQVVDSGFSDLGSIESTTENYENPSSYDSTMGGSICGNSSSQSSC-------SYGGLSSS 1595
Q ++ + PSS + G Q S S+G L S
Sbjct: 4074 QLLLVQ-----------PQPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAGGGSHGQLGSG 4122
Query: 1596 SSLTQSSC--VVTQQMASMGSSCSMMQQSSVQPAANCSIKSPQSCVVERPPSNQQ-QQPP 1652
SS SS ++ Q S+G M Q+ + PQ ++ERP N QPP
Sbjct: 4123 SSSEASSVPHLLAQPSVSLGDQPGSMTQN---------LLGPQQPMLERPMQNNTGPQPP 4173
Query: 1653 PPPP--QQPQPPP--------------------PQPQPAPQPPPPQQQPQ--------QQ 1682
P P Q Q P PQ P QQQ Q QQ
Sbjct: 4174 KPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQLQQ 4233
Query: 1683 PQPQPQQPPPPPPPQQQPPLSQ---CSMNNSFTPAPMIMEIPESGSTGNISIYERIPGDF 1739
Q Q PP P Q PL C P P + E G+ R+P
Sbjct: 4234 SQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPPRLPAPP 4293
Query: 1740 GAGSYSQPSATFSLAKLQQLTNTIMDP-HAMPYSHSPAVTSYATSVSLSNTGL---AQLA 1795
GA S T ++ P H P SP + + ++ L AQL
Sbjct: 4294 GALS----------------TGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLP 4337
Query: 1796 PSHPLAGTPQAQA-TMTPPPNLAS-TTMNLTSPLLQCNMSATN--IGIPHTQRLQGQMPV 1851
P+HP GTP+ Q T+ PPP S L L + + + TQ+ + V
Sbjct: 4338 PTHP--GTPKPQGPTLEPPPGRVSPAAAQLADTLFSKGLGPWDPPDNLAETQKPEQSSLV 4395
Query: 1852 KGHI-SIRSKSAPLPSAAAHQQQ 1873
GH+ + + P S + +Q+
Sbjct: 4396 PGHLDQVNGQVVPEASQLSIKQE 4418
Score = 52.8 bits (125), Expect = 3e-06
Identities = 55/229 (24%), Positives = 85/229 (37%), Gaps = 26/229 (11%)
Query: 1614 SSCSMMQQSSVQPAANCSIKSPQSCVVERPPSNQQQQPPPPPPQQPQPPPPQPQPAPQPP 1673
S S +++S + P +SP S +E P S + P PP + P P P+ P P
Sbjct: 510 SPFSPLEESPLSPPE----ESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSP 565
Query: 1674 PPQQQ-----PQQQP-QPQPQQPP--PPP------PPQQQPPLSQCSMNNSFTPAPMIME 1719
PP+ P++ P P P++ P PPP PP ++ PLS + +P P
Sbjct: 566 PPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASR 625
Query: 1720 IPESGSTGNISIYERIPGDFGAGSYSQPSATFSLAKLQQLTNTIMDPHAMPYSHSPAVTS 1779
+ +S S P L+ L ++ P P S P +
Sbjct: 626 LSPPPEDSPMSPPPE------ESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEES- 678
Query: 1780 YATSVSLSNTGLAQLAPSHPLAGTPQAQATMTPPPNLASTTMNLTSPLL 1828
TS + L+ P + P+ PP + + SPLL
Sbjct: 679 -PTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLL 726
Score = 51.2 bits (121), Expect = 1e-05
Identities = 157/721 (21%), Positives = 230/721 (31%), Gaps = 91/721 (12%)
Query: 1150 KGWPKGKSRKPIHWKKRPGRKPGFKLSREIMPVSTQACVIEPIVSIPKAGRKPKIQESEE 1209
+G PKG H ++PG L E P+ +EP + P + E
Sbjct: 393 QGQPKGG-----HVTSMQPKEPG-PLQCEAKPLGKAGVQLEPQLEAP-------LNEEMP 439
Query: 1210 TVEPKEDMPL-PEERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSNSPETETKEP 1268
+ P E+ PL P + EA EE AS P S E P
Sbjct: 440 LLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPAS---PLPEALHLSRPLEESPLSP 496
Query: 1269 EVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDEDDGHLESTK 1328
EE P E S E+ L PE E A ET + +A ES
Sbjct: 497 PPEESPLSPP-PESSPFSPLEESPLSPPE-ESPPSPALETPLSPPPEASPLSPPFEESPL 554
Query: 1329 KKELEEQPTR------------EDVKEEPGVQESFLDANMQKSREKIKDKEETELDSEEE 1376
EE PT E+ P +ES + + SR +E EE
Sbjct: 555 SPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEE 614
Query: 1377 QPSHDTSVVSEQMAGSEDDHEEDSHTKEELIELKEEEEIPHSELD-LETVQAVQSLTQEE 1435
P S ED +E P E+ L + V L+
Sbjct: 615 SPLSPPPEASRLSPPPEDSPMSPPP--------EESPMSPPPEVSRLSPLPVVSRLSPPP 666
Query: 1436 SSEHEGAYQDCEETLAACQTLQSYTQADEDPQMSMVEDCHASEHNSPISSVQSHPSQSVR 1495
+ T + + ++ P ED AS P S+ S P +
Sbjct: 667 EESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASP--PPEDSLMSLPLEESP 724
Query: 1496 SVSSPNVPAL----ESGYTQISPEQGSLSAPSMQNMETSPMMDVPSVSDHSQQVVDSGFS 1551
+ P P L E + PE+ LS P + SP + P +S ++
Sbjct: 725 LLPLPEEPQLCPRSEGPHLSPRPEEPHLS-PRPEEPHLSPQAEEPHLSPQPEEPCLCAVP 783
Query: 1552 DLGSIESTTENYENPSSYDSTMGGSICGNSSSQSSCSYGGLSSSSSLTQSSCVVTQQMAS 1611
E P G + S + + C+ Q S
Sbjct: 784 ------------EEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEES 831
Query: 1612 MGSSCSMMQQSSVQPAANCSIKSPQSCVVERPPSNQQQQPPPPPPQQPQPPPPQPQPAPQ 1671
S S ++ + P S SP+ +E+PP + + + PP P Q P P+ P
Sbjct: 832 HLSPQS--EEPCLSPRPEESHLSPE---LEKPPLSPRPEKPPEEPGQC----PAPEELPL 882
Query: 1672 PPPPQQQPQQQP---QP---QPQQPPPPPPPQQQP--PLSQCSMNNSFTP----APMIME 1719
PPP +P P +P +P +PP P P++ P P + S++ P P +
Sbjct: 883 FPPP-GEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSP 941
Query: 1720 IPESGSTGNISIYERIPGDFGAGSYSQPSATFSLAKLQQLTNTIMDPHAMPYSHSPAVTS 1779
I + + +S + FGA S P + + L+ T P A P
Sbjct: 942 IITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPILE--TPISPPPEANCTDPEPVPPM 999
Query: 1780 YATSVSLSNTGLAQLAPSHPLAGTPQAQATMTPPPNLASTTMNLTSPLLQCNMSATNIGI 1839
S G A PL PQ P L + + SP QC+ A + +
Sbjct: 1000 ILPPSPGSPVGPASPILMEPL--PPQCS------PLLQHSLVPQNSPPSQCSPPALPLSV 1051
Query: 1840 P 1840
P
Sbjct: 1052 P 1052
Score = 50.1 bits (118), Expect = 2e-05
Identities = 156/711 (21%), Positives = 230/711 (32%), Gaps = 106/711 (14%)
Query: 1047 EPFEDSDSERPMPRLEPTFEIDEEEEEEDENELFPREYFRRLSSQDVLRCQS--SSKRKS 1104
EP ++ MP L P E E+ P E R + L + S
Sbjct: 427 EPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLS 486
Query: 1105 KDEEEDEESDDADDTPILKPVSLLRKRDVKNSPLEPDTSTPLKKKKGWPKGKSRKPIHWK 1164
+ EE S +++P+ P ++ SPL P +P P P+
Sbjct: 487 RPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESP-------PSPALETPL--- 536
Query: 1165 KRPGRKPGFKLSREIMPVSTQACVIEPIVSIPKAGR-KPKIQESEETVEPKED--MPLPE 1221
P E P+S + P P+A R P +ES + P+E P PE
Sbjct: 537 SPPPEASPLSPPFEESPLSPPPEEL-PTSPPPEASRLSPPPEESPMSPPPEESPMSPPPE 595
Query: 1222 ERK-----EEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSNSPETE----TKEPEVEE 1272
+ EE + EE+ +A+ P P DS SP E + PEV
Sbjct: 596 ASRLFPPFEESPLSPPPEESPLSPPPEASRLSPP---PEDSPMSPPPEESPMSPPPEVSR 652
Query: 1273 EEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDEDDGHLESTKKKEL 1332
P VS R S ++ P PEE + A +D
Sbjct: 653 LSPLPVVS---RLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDS------------- 696
Query: 1333 EEQPTREDVKEEPGVQESFLDANMQKSREKIKDKEETELDSEEEQPSHDTSVVSEQMAGS 1392
P ED P ++S + +++S + EE +L E P S
Sbjct: 697 PTSPPPEDSPASPPPEDSLMSLPLEES-PLLPLPEEPQLCPRSEGPHL-----------S 744
Query: 1393 EDDHEEDSHTKEELIELKEEEEIPHSELDLETVQAVQSLTQEE---SSEHEGAY--QDCE 1447
E + E L + E PH L + + EE S + EG + E
Sbjct: 745 PRPEEPHLSPRPEEPHLSPQAEEPH--LSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPE 802
Query: 1448 ETLAACQTLQSYTQADEDPQMSMV--EDCHASE-HNSPISSVQSHPSQSVRSVSSPNVPA 1504
E + QT E+P +S V E C + + S +S P S R S P
Sbjct: 803 ELHLSPQT--------EEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPE 854
Query: 1505 LESGYTQISPEQGSLSAPSMQNMETSPMMDVPSVSDHSQQVVDSGFSDLGSIESTTENYE 1564
LE PE+ E P+ P S + + S+ G + E
Sbjct: 855 LEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEE 914
Query: 1565 NPSSYDSTMGGSICGNSSSQSSCSYGGLSSSSSLTQSSCVVTQQMASMGSSCSMMQ---- 1620
P S S + S S + S ++T S ++
Sbjct: 915 LPLS------------PSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGELEYPFG 962
Query: 1621 ----QSSVQPAANCSIKSPQSCVVERPPSNQQQQPPPPPPQQPQPPPPQP-QPAP----Q 1671
P A +++P + PP P P PP P P P PA +
Sbjct: 963 AKGDSDPESPLAAPILETP----ISPPPEANCTDPEPVPPMILPPSPGSPVGPASPILME 1018
Query: 1672 PPPPQQQPQQQPQPQPQQPPPPPPPQQQPPLSQCSMNNSFTPAPMIMEIPE 1722
P PPQ P Q PQ PP Q PP S+ + +P ++ + +
Sbjct: 1019 PLPPQCSPLLQHSLVPQN---SPPSQCSPPALPLSVPSPLSPIGKVVGVSD 1066
Score = 49.7 bits (117), Expect = 3e-05
Identities = 56/205 (27%), Positives = 71/205 (34%), Gaps = 42/205 (20%)
Query: 1634 SPQSCVVERPPSNQQQQPPPPPPQQPQPPPPQPQPAPQPPPPQQQPQQQPQPQPQQPPPP 1693
+P++ VE +P PPP Q P P P P P QP P+ PPP
Sbjct: 2332 TPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPP 2391
Query: 1694 P------PPQQQP----------PLSQCSMNNSFTPAPMIMEI----PESGSTGNISIYE 1733
P PP+ P P SQ S + TP P+ E P + + Y
Sbjct: 2392 PESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYS 2451
Query: 1734 RIPGDFGAGSYSQPSATFSLAKLQQLTNTIMDPHAMPYSHSPAVTSYATSV---SLSNTG 1790
R P S+P + A L H P P V A S+ SL G
Sbjct: 2452 RPP--------SRPQSRDPFAPL----------HKPPRPQPPEVAFKAGSLAHTSLGAGG 2493
Query: 1791 LAQLAPSHPLAGTPQAQATMTPPPN 1815
P+ P AG A+ PPN
Sbjct: 2494 FPAALPAGP-AGELHAKVPSGQPPN 2517
Score = 49.3 bits (116), Expect = 4e-05
Identities = 57/245 (23%), Positives = 93/245 (37%), Gaps = 30/245 (12%)
Query: 1644 PSNQQQQPPPPPPQQPQPPPPQPQPAPQPP------PPQQQPQQQPQPQ------PQQPP 1691
P N++ PPP + P PPP+ P PP PP ++ P P+ P +
Sbjct: 433 PLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEES 492
Query: 1692 PPPPPQQQPPLSQCSMNNSFTPAPMIMEIPESGSTGNISIYERIPGDFGAGSYSQPSATF 1751
P PP ++ PLS ++ F+P P S + ++ + A S P
Sbjct: 493 PLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEES 552
Query: 1752 SLAKLQQLTNTIMDPHAM----PYSHSPAVTSYATSVSLSNTGLAQLAP---SHPLAGTP 1804
L+ + T P A P SP S ++L P PL+ P
Sbjct: 553 PLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPP 612
Query: 1805 QAQATMTPPPNLASTT-----MNLTSPLLQCNMSATNIGIPHTQRLQGQMPVKGHISIRS 1859
+ ++ ++PPP + + ++ P + MS P RL +PV +S
Sbjct: 613 E-ESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPP----PEVSRL-SPLPVVSRLSPPP 666
Query: 1860 KSAPL 1864
+ +PL
Sbjct: 667 EESPL 671
Score = 45.1 bits (105), Expect = 7e-04
Identities = 86/414 (20%), Positives = 138/414 (33%), Gaps = 30/414 (7%)
Query: 1581 SSSQSSCSYGGLSSSSSLTQSSCVVTQQMASMGSSCSM--MQQS----SVQPAANCSIKS 1634
SS Q + GL +T QQ GS + +QQS S QP +
Sbjct: 3836 SSPQLAQQGQGLMGHRLVTAQQQQQQQQHQQQGSMAGLSHLQQSLMSHSGQPKLSAQPMG 3895
Query: 1635 PQSCVVERPPSNQQQQPPPPPPQQPQPPPPQPQPAPQPPPPQQQPQQQPQPQPQQPPPPP 1694
+ ++ QQQQ QQ Q Q Q QQQ QQQ Q Q QQ
Sbjct: 3896 SLQQLQQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQLQQQQQQL 3955
Query: 1695 PPQQQPPLSQCSMNNSFTPAPMIME-----IPESGSTGNISIYERIPGDFGAGSYSQPSA 1749
QQQ Q ++ + P+ +++ +P +S P A
Sbjct: 3956 QQQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQVALGPGMPAK-PLQHFSSPGA 4014
Query: 1750 TFSLAKLQQLTNTIMDPHAM------PYSHSPAVTSYATSVSLSNTGLAQLAPSHPLAGT 1803
L +DP P +H + T+ T ++ PS L+G
Sbjct: 4015 LGPTLLLTGKEQNTVDPAVSSEATEGPSTHQGGPLAIGTTPESMATEPGEVKPS--LSGD 4072
Query: 1804 PQAQATMTPPPNLASTTMNLTSPLLQCNMSATNIGIPHTQ--RLQGQMPVKGHISIRSKS 1861
Q + P P +++ L PL + + HT GQ+ S++
Sbjct: 4073 SQL-LLVQPQPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAGGGSHGQL----GSGSSSEA 4127
Query: 1862 APLPSAAAHQQQLYGRSPSAVAMQ-AGPRALAVQRGMNMGVNLMPTPAYNV--NSMNMNT 1918
+ +P A G P ++ GP+ ++R M P V + +
Sbjct: 4128 SSVPHLLAQPSVSLGDQPGSMTQNLLGPQQPMLERPMQNNTGPQPPKPGPVLQSGQGLPG 4187
Query: 1919 LNAMNSYRMTQPMMNSSYHSNPAYMNQTAQYPMQMQMGMMGSQAYTQQPMQPNP 1972
+ M + + + NP + + Q Q+Q +M Q Q ++ P
Sbjct: 4188 VGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQLQQSQAVRQTP 4241
Score = 43.9 bits (102), Expect = 0.002
Identities = 19/55 (34%), Positives = 27/55 (49%)
Query: 1649 QQPPPPPPQQPQPPPPQPQPAPQPPPPQQQPQQQPQPQPQQPPPPPPPQQQPPLS 1703
+Q PPP++P PPP P+P PP + + +P + P P P P P S
Sbjct: 4904 RQLSAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPES 4958
Score = 40.4 bits (93), Expect = 0.018
Identities = 20/69 (28%), Positives = 29/69 (42%), Gaps = 10/69 (14%)
Query: 1643 PPSNQQQQPPPPPPQQPQPPPPQP------QPAPQPPPPQQQP----QQQPQPQPQQPPP 1692
PP + PP P P PP +P +P +PP P P + +P+P+ PP
Sbjct: 4909 PPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKPRARPP 4968
Query: 1693 PPPPQQQPP 1701
+PP
Sbjct: 4969 EEGEDSRPP 4977
Score = 40.0 bits (92), Expect = 0.023
Identities = 21/67 (31%), Positives = 29/67 (43%), Gaps = 7/67 (10%)
Query: 260 IECKTCSSCRDQGKNADNMLFCDSCDRGFHMECCDPPLTRMPKGMW------ICQICRPR 313
+E C+ C G+ D + FC SC +H C D LT + W +CQ CR
Sbjct: 224 LEEARCAVCEGPGELCD-LFFCTSCGHHYHGACLDTALTARKRAGWQCPECKVCQACRKP 282
Query: 314 KKGRKLL 320
K+L
Sbjct: 283 GNDSKML 289
Score = 39.3 bits (90), Expect = 0.039
Identities = 71/324 (21%), Positives = 107/324 (33%), Gaps = 39/324 (12%)
Query: 991 EEEPESPRSSSPPILTKPTLKRKKPFLHRRRRVRKRKHHNSSVVTETISETTEVLDEPFE 1050
EE P SP P P R P + S E + P
Sbjct: 550 EESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLS 609
Query: 1051 DSDSERPMP------RLEPTFEIDEEEEEEDENELFPREYFRRLSSQDVLRCQSSSKRKS 1104
E P+ RL P E +E+ + P RLS V+ R S
Sbjct: 610 PPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVV------SRLS 663
Query: 1105 KDEEEDEESDDADDTPILKPVSLLRKRDVKNSPLEPDTSTPLKKKKGWPKGK-SRKPIHW 1163
EE S +++P P R + P + TS P + P + S +
Sbjct: 664 PPPEESPLSPPPEESPTSPPPEASR---LSPPPEDSPTSPPPEDSPASPPPEDSLMSLPL 720
Query: 1164 KKRPGRKPGFKLSREIMPVSTQACVIEPIVSIPKAGRKPKIQESEETVEPKEDMPLPEER 1223
++ P +P Q C P P +P+ E + P+ + P +
Sbjct: 721 EESPLLP---------LPEEPQLC---PRSEGPHLSPRPE----EPHLSPRPEEPHLSPQ 764
Query: 1224 KEEEEMQAEAEE----AEEGEEEDAASSEVPAASPADSSNSPETETKEPEVEEEEEKPRV 1279
EE + + EE A E + +E P SP +T+EP + E+P +
Sbjct: 765 AEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCL 824
Query: 1280 S---EEQRQSEEEQQELEEPEPEE 1300
S EE S + ++ P PEE
Sbjct: 825 SPQPEESHLSPQSEEPCLSPRPEE 848
Score = 35.8 bits (81), Expect = 0.43
Identities = 37/131 (28%), Positives = 49/131 (37%), Gaps = 31/131 (23%)
Query: 1634 SPQSCVVERPPSNQQQQPPPPP-------PQQPQ--------PPPPQPQPAPQPPPPQQQ 1678
SP ++ PP Q P P P +P+ PP P P AP PP
Sbjct: 2155 SPGELFLKLPPQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGA 2214
Query: 1679 PQQQPQPQPQQ--PPPPPPPQQQPPLSQCSMNNSFTPAPMIMEIPESGSTGNISIYERIP 1736
+ QP + PP P+ QP TP P + P S N+++ E P
Sbjct: 2215 SSRPGAGQPGEFHTTPPGTPRHQPS----------TPDPFLK--PRCPSLDNLAVPES-P 2261
Query: 1737 GDFGAGSYSQP 1747
G G G S+P
Sbjct: 2262 G-VGGGKASEP 2271
Score = 35.4 bits (80), Expect = 0.57
Identities = 17/62 (27%), Positives = 26/62 (41%), Gaps = 6/62 (9%)
Query: 207 PICSFCLGTKEQNREKKPEELISCADCGNSGHPSCLKFSPELTVRVKALRWQCIECKTCS 266
P C C ++ + K ++ C C H CLK E + A W+C C+ C
Sbjct: 271 PECKVCQACRKPGNDSK---MLVCETCDKGYHTFCLKPPME---ELPAHSWKCKACRVCR 324
Query: 267 SC 268
+C
Sbjct: 325 AC 326
Score = 34.7 bits (78), Expect = 0.96
Identities = 20/60 (33%), Positives = 26/60 (43%), Gaps = 3/60 (5%)
Query: 209 CSFCLGTKEQNREKKPEELISCADCGNSGHPSCLKFSPELTVRVKALRWQCIECKTCSSC 268
C C+ + + P L+ C DC S H CL P LTV W+C C +C C
Sbjct: 1424 CVECIVCEVCGQASDPSRLLLCDDCDISYHTYCLD-PPLLTVPKGG--WKCKWCVSCMQC 1480
Score = 34.3 bits (77), Expect = 1.3
Identities = 16/57 (28%), Positives = 25/57 (43%)
Query: 1665 QPQPAPQPPPPQQQPQQQPQPQPQQPPPPPPPQQQPPLSQCSMNNSFTPAPMIMEIP 1721
Q PAP+PP +Q PPP + PP S + + + P ++E+P
Sbjct: 4881 QESPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPASPPTEPLVELP 4937
Score = 33.1 bits (74), Expect = 2.8
Identities = 86/390 (22%), Positives = 123/390 (31%), Gaps = 52/390 (13%)
Query: 924 EEQPSQDGKPDLPKRRLSEGVEPWRGQLKKSPEALKCRLTEGSERLPRRYS-EGDRAVLR 982
EE P + P L + P SP + L+ E LP E R
Sbjct: 516 EESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRL--- 572
Query: 983 GFSESSEEEEEPESPRSSSPPILTKPTLKRKKPFLHRRRRVRKRKHHNSSVVTETISETT 1042
S EE P SP P+ P R P + S E +
Sbjct: 573 ----SPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSP 628
Query: 1043 EVLDEPFEDSDSERPMP------RLEPTFEIDEEEEEEDENELFPREYFRRLSSQDVLRC 1096
D P E PM RL P + +E+ L P +
Sbjct: 629 PPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPP------EESPTSP 682
Query: 1097 QSSSKRKSKDEEEDEESDDADDTPILKPVSLLRKRDVKNSPLEPDTSTPLKKKKGWPKGK 1156
+ R S E+ S +D+P P + + + PLE PL ++ +
Sbjct: 683 PPEASRLSPPPEDSPTSPPPEDSPASPPP----EDSLMSLPLEESPLLPLPEEPQLCP-R 737
Query: 1157 SRKPIHWKKRPGRKPGFKLSREIMPVSTQACVIEPIVSIPKAGRKPKIQESEETVEPKED 1216
S P H RP +P E EP +S P+ +E + +P+E
Sbjct: 738 SEGP-HLSPRP-EEPHLSPRPE-----------EPHLS-------PQAEEPHLSPQPEEP 777
Query: 1217 M--PLPEERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPADS----SNSPETETKEPEV 1270
+PEE + + + E + +E P SP S PE P+
Sbjct: 778 CLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQS 837
Query: 1271 EEEEEKPRVSEEQRQSEEEQQELEEPEPEE 1300
EE PR E E E+ L P PE+
Sbjct: 838 EEPCLSPRPEESHLSPELEKPPL-SPRPEK 866
Score = 31.6 bits (70), Expect = 8.2
Identities = 26/93 (27%), Positives = 31/93 (33%), Gaps = 16/93 (17%)
Query: 1647 QQQQPPPPPPQQP------------QPPPPQPQPAPQPPPPQQQPQQQPQPQPQQPPPPP 1694
+Q+ P P PP Q Q P P+ PP P P +P P
Sbjct: 4880 KQESPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPASPPTEPLVELPTE 4939
Query: 1695 PPQQQP---PLSQCSMNNSFTPAPMIMEIPESG 1724
P + P PL S S P P PE G
Sbjct: 4940 PLAEPPVPSPLPLASSPESARPKPRARP-PEEG 4971
>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
Length = 2400
Score = 82.8 bits (203), Expect = 3e-15
Identities = 91/336 (27%), Positives = 145/336 (43%), Gaps = 25/336 (7%)
Query: 1205 QESEETVEPK-EDMPLPEERKEEEEMQAEAEEAE--EGEEEDAASSEVPAASPADSSNSP 1261
QE+E +P+ ED+ PE E E Q E+E+ E E E E SE A A+ P
Sbjct: 1861 QEAEGEAQPESEDVEAPEA---EGEAQPESEDVETPEAEWEVQPESEGAEAPEAEKEAQP 1917
Query: 1262 ETETKEP-EVEEEEEKPRVSEEQRQSEEEQQELE-EPEPEEEEDAAAETAQNDDHDADDE 1319
ETE+ E E E E+E E +++EE QE E + +PE E + E + +++D
Sbjct: 1918 ETESVEALETEGEDEPESEGAEAQEAEEAAQEAEGQTQPESEVIESQEAEEEAQPESEDV 1977
Query: 1320 DDGHLE-STKKKELEEQPTREDV---KEEPGVQESFLDANMQKSREKIKDKEETELDSEE 1375
+ +E T++ E E QP EDV + E +QE+ +A + + + K E E E
Sbjct: 1978 EALEVEVETQEAEGEAQPESEDVEAPEAEGEMQEAEEEAQPESDGVEAQPKSEGEEAQEV 2037
Query: 1376 EQPSHDTSVVSEQMAGSEDDHEEDSHTKEELIELKEEEEIPHSELDLETVQAVQSLTQEE 1435
E + T ++ + + E + +E E++E E H E + Q + Q E
Sbjct: 2038 EGETQKTEGDAQPESDGVEAPEAEEEAQEAEGEVQEAEGEAHPESEDVDAQEAEGEAQPE 2097
Query: 1436 SS-----EHEGAYQDCEETLAACQTLQSYTQADEDPQMSMVEDCHASEHNSPIS-SVQSH 1489
S E EG Q E A T+ + P+ +E A P S V++
Sbjct: 2098 SEGVEAPEAEGEAQKAEGIEA------PETEGEAQPESEGIEAPEAEGEAQPESEGVEAQ 2151
Query: 1490 PSQSVRSVSSPNVPALESGYTQISPEQGSLSAPSMQ 1525
++ S + A E+ + PE + AP +
Sbjct: 2152 DAEGEAQPESEGIEAQEA-EEEAQPELEGVEAPEAE 2186
Score = 81.3 bits (199), Expect = 9e-15
Identities = 79/347 (22%), Positives = 145/347 (41%), Gaps = 33/347 (9%)
Query: 1206 ESEETVEPK-EDMPLPEERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSNSPETE 1264
E+E +P+ ED+ PE E E+Q E+E AE E E A E + ++ E E
Sbjct: 1878 EAEGEAQPESEDVETPEA---EWEVQPESEGAEAPEAEKEAQPETESVEALETEGEDEPE 1934
Query: 1265 TKEPEVEEEEEKPRVSEEQRQSEE---EQQELEEPEPEEEEDAAAETAQNDDHDADDEDD 1321
++ E +E EE + +E Q Q E E QE EE E ED A + + +A+ E
Sbjct: 1935 SEGAEAQEAEEAAQEAEGQTQPESEVIESQEAEEEAQPESEDVEALEVEVETQEAEGEAQ 1994
Query: 1322 GHLESTKKKELEEQPTREDVKEEPGVQESFLDANMQKSREKIKDKE-ETELDSEEEQPSH 1380
E + E E + ++ +EE + ++A + E+ ++ E ET+ + QP
Sbjct: 1995 PESEDVEAPEAEGE--MQEAEEEAQPESDGVEAQPKSEGEEAQEVEGETQKTEGDAQPES 2052
Query: 1381 D------TSVVSEQMAGSEDDHEEDSHTKEELIELKEEE----------EIPHSELDLET 1424
D +++ G + E ++H + E ++ +E E E P +E + +
Sbjct: 2053 DGVEAPEAEEEAQEAEGEVQEAEGEAHPESEDVDAQEAEGEAQPESEGVEAPEAEGEAQK 2112
Query: 1425 VQAVQSLTQEESSEHEGAYQDCEETLAACQTLQSYTQADE-----DPQMSMVEDCHASEH 1479
+ +++ E ++ E + E Q +A + P+ +E A E
Sbjct: 2113 AEGIEAPETEGEAQPESEGIEAPEAEGEAQPESEGVEAQDAEGEAQPESEGIEAQEAEEE 2172
Query: 1480 NSP-ISSVQSHPSQSVRSVSSPNVPALESGYTQISPEQGSLSAPSMQ 1525
P + V++ ++ S + A E+ + PE + AP +
Sbjct: 2173 AQPELEGVEAPEAEGEAQPESEGIEAPEA-EGEAQPELEGVEAPEAE 2218
Score = 75.5 bits (184), Expect = 5e-13
Identities = 100/497 (20%), Positives = 180/497 (36%), Gaps = 61/497 (12%)
Query: 1225 EEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSNSPETETKEPEVEEEEEKPRVSEEQR 1284
E E + EA+ EG E A + A S + E E E E + E V +
Sbjct: 1836 EAPEAEGEAQPESEGVEAPEAEGDAQEAEGEAQPESEDVEAPEAEGEAQPESEDVETPEA 1895
Query: 1285 QSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQPTREDVKEE 1344
+ E + + PE E++A ET + + + ED+ E + +E EE + + +
Sbjct: 1896 EWEVQPESEGAEAPEAEKEAQPETESVEALETEGEDEPESEGAEAQEAEEAAQEAEGQTQ 1955
Query: 1345 PGVQESFLDANMQKSREKIKDKEETELDSEEEQPSHDTSVVSEQMAGSEDDHEEDSHTKE 1404
P ++ + +S+E +EE + +SE+ + + + V +++ G ED E
Sbjct: 1956 P-------ESEVIESQEA---EEEAQPESEDVE-ALEVEVETQEAEGEAQPESEDVEAPE 2004
Query: 1405 ELIELKEEEEIPHSELDLETVQAVQSLTQEESSEHEGAYQDCEETLAACQTLQSYTQADE 1464
E++E EE E D V+A EE+ E EG Q T+ D
Sbjct: 2005 AEGEMQEAEEEAQPESD--GVEAQPKSEGEEAQEVEGETQK--------------TEGDA 2048
Query: 1465 DPQMSMVEDCHASEHNSPISSVQSHPSQSVRSVSSPNVPALESGYTQISPEQGSLSAPSM 1524
P+ VE A E + ++ S +V A E+ + PE + AP
Sbjct: 2049 QPESDGVEAPEAEEEAQEAEG-EVQEAEGEAHPESEDVDAQEA-EGEAQPESEGVEAPEA 2106
Query: 1525 Q-NMETSPMMDVPSVSDHSQQVVDSGFSDLGSIESTTENYENPSSYDSTMGGSICGNSSS 1583
+ + + ++ P +Q + IE+ E + G +
Sbjct: 2107 EGEAQKAEGIEAPETEGEAQ-------PESEGIEAPEAEGEAQPESEGVEAQDAEGEAQP 2159
Query: 1584 QSSCSYGGLSSSSSLTQSSCVVTQQMASMGSSCSMMQQSSVQPAANCSIKSPQSCVVERP 1643
+S G+ + + ++ + A + + ++ P+ VE P
Sbjct: 2160 ESE----GIEAQEAEEEAQPELEGVEAPEAEGEAQPESEGIEAPEAEGEAQPELEGVEAP 2215
Query: 1644 PSNQQQQPPPPPPQQP------QPPPPQPQPAPQPPPPQ--------QQPQQQPQPQPQQ 1689
+ ++ QP P + P QP + PQ ++ + P P+
Sbjct: 2216 EAEEEAQPEPEGVETPEAEGEAQPESEGETQGEKKGSPQVSLGDGQSEEASESSSPVPED 2275
Query: 1690 PPPPPP------PQQQP 1700
P PPP P Q+P
Sbjct: 2276 RPTPPPSPGGDTPHQRP 2292
Score = 75.5 bits (184), Expect = 5e-13
Identities = 99/408 (24%), Positives = 165/408 (40%), Gaps = 40/408 (9%)
Query: 1206 ESEETVEPKEDMPLPEERKEEEEMQ---AEAEEAEEGEEE----DAASSEVPAASPADSS 1258
E+E+ +P+ + E + E+E + AEA+EAEE +E SEV + A+
Sbjct: 1910 EAEKEAQPETESVEALETEGEDEPESEGAEAQEAEEAAQEAEGQTQPESEVIESQEAEEE 1969
Query: 1259 NSPETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADD 1318
PE+E +VE E + E + +++ E +++E PE E E A E AQ + +
Sbjct: 1970 AQPESE----DVEALEVEVETQEAEGEAQPESEDVEAPEAEGEMQEAEEEAQPESDGVEA 2025
Query: 1319 EDDGHLESTKKKELEEQPTREDVK-EEPGVQESFLDANMQKSREKIKDKE-ETELDSEEE 1376
+ E ++ E E Q T D + E GV+ + Q++ ++++ E E +SE+
Sbjct: 2026 QPKSEGEEAQEVEGETQKTEGDAQPESDGVEAPEAEEEAQEAEGEVQEAEGEAHPESEDV 2085
Query: 1377 QPSHDTSVVSEQMAGSEDDHEEDSHTKEELIELKEE--EEIPHSELDLETVQAVQSLTQE 1434
+ G E E K E IE E E P SE +E +A E
Sbjct: 2086 DAQEAEGEAQPESEGVEAPEAEGEAQKAEGIEAPETEGEAQPESE-GIEAPEAEGEAQPE 2144
Query: 1435 ----ESSEHEGAYQDCEETLAACQTLQSYTQADEDPQMSMVEDCHASEHNSPISSVQSHP 1490
E+ + EG Q E + A + + + P++ VE A P S P
Sbjct: 2145 SEGVEAQDAEGEAQPESEGIEAQE-----AEEEAQPELEGVEAPEAEGEAQPESEGIEAP 2199
Query: 1491 SQSVRSVSSPNVPALES--GYTQISPEQGSLSAPSMQNMETSPMMDVPSVSDHS---QQV 1545
+ P + +E+ + PE + P + E P + + + Q
Sbjct: 2200 --EAEGEAQPELEGVEAPEAEEEAQPEPEGVETPEAEG-EAQPESEGETQGEKKGSPQVS 2256
Query: 1546 VDSGFSDLGSIESTTENYENPSSYDSTMG-------GSICGNSSSQSS 1586
+ G S+ S S+ + P+ S G GS G SSS++S
Sbjct: 2257 LGDGQSEEASESSSPVPEDRPTPPPSPGGDTPHQRPGSQTGPSSSRAS 2304
Score = 72.8 bits (177), Expect = 3e-12
Identities = 105/484 (21%), Positives = 173/484 (35%), Gaps = 47/484 (9%)
Query: 1221 EERKEEEEMQA-EAE-EAEEGEEEDAASSEVPAASPADSSNSPETETKEP-----EVEEE 1273
E + E E ++A EAE +A+E E E SE A A+ PE+E E EV+ E
Sbjct: 1843 EAQPESEGVEAPEAEGDAQEAEGEAQPESEDVEAPEAEGEAQPESEDVETPEAEWEVQPE 1902
Query: 1274 EEKPRVSEEQRQSEEEQQELEEPEPE-----EEEDAAAETAQNDDHDADDEDDGHLESTK 1328
E E +++++ E + +E E E E E A A+ A+ +A+ + E +
Sbjct: 1903 SEGAEAPEAEKEAQPETESVEALETEGEDEPESEGAEAQEAEEAAQEAEGQTQPESEVIE 1962
Query: 1329 KKELEE--QPTREDVKE-EPGVQESFLDANMQKSREKIKDKE---ETELDSEEEQPSHDT 1382
+E EE QP EDV+ E V+ + Q E ++ E E + EE QP D
Sbjct: 1963 SQEAEEEAQPESEDVEALEVEVETQEAEGEAQPESEDVEAPEAEGEMQEAEEEAQPESDG 2022
Query: 1383 SVVSEQMAGSEDDHEEDSHTKEELIELKEEEEIPHSELDLETVQAVQSLTQEESSEH-EG 1441
+ G E E K E E + + E + E +A + + E H E
Sbjct: 2023 VEAQPKSEGEEAQEVEGETQKTEGDAQPESDGVEAPEAEEEAQEAEGEVQEAEGEAHPES 2082
Query: 1442 AYQDCEETLAACQTLQSYTQADEDPQMSMVEDCHASEHNSPISSVQSHPSQSVRSVSSPN 1501
D +E + + P+ VE A +++ ++ S
Sbjct: 2083 EDVDAQE-----------AEGEAQPESEGVEAPEAEGEAQKAEGIEAPETEGEAQPESEG 2131
Query: 1502 VPALESGYTQISPEQGSLSAPSMQNMETSPMMDVPSVSDHSQQVVDSGFSDLGSIESTTE 1561
+ A E+ + PE + A + E P S +Q+ + +L +E+
Sbjct: 2132 IEAPEA-EGEAQPESEGVEAQDAEG-EAQP----ESEGIEAQEAEEEAQPELEGVEAPEA 2185
Query: 1562 NYENPSSYDSTMGGSICGNSSSQSSCSYGGLSSSSSLTQSSCVVTQQMASMGSSCSMMQQ 1621
E + G + + + + + V T + Q
Sbjct: 2186 EGEAQPESEGIEAPEAEGEAQPELEGVEAPEAEEEAQPEPEGVETPEAEGEA------QP 2239
Query: 1622 SSVQPAANCSIKSPQSCVVERPPSNQQQQPPPPPPQQPQPPPPQPQPAPQPPPPQQQPQQ 1681
S SPQ + + + P P +P PP P+P P Q+P
Sbjct: 2240 ESEGETQGEKKGSPQVSLGDGQSEEASESSSPVPEDRPTPP-----PSPGGDTPHQRPGS 2294
Query: 1682 QPQP 1685
Q P
Sbjct: 2295 QTGP 2298
Score = 70.9 bits (172), Expect = 1e-11
Identities = 111/457 (24%), Positives = 173/457 (37%), Gaps = 49/457 (10%)
Query: 1190 EPIVSIPKAGRKPKIQESEETVEPKEDMPLPEERKEEEEMQAEAEEAEE---GEEEDAAS 1246
E + ++ G E E E +E E + + E E++EAEE E ED +
Sbjct: 1920 ESVEALETEGEDEPESEGAEAQEAEEAAQEAEGQTQPESEVIESQEAEEEAQPESEDVEA 1979
Query: 1247 SEVPA-ASPADSSNSPETETKE-PEVE------EEEEKPR---VSEEQRQSEEEQQELEE 1295
EV A+ PE+E E PE E EEE +P V + + EE QE+E
Sbjct: 1980 LEVEVETQEAEGEAQPESEDVEAPEAEGEMQEAEEEAQPESDGVEAQPKSEGEEAQEVEG 2039
Query: 1296 PEPEEEEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQPTREDV----------KEEP 1345
+ E DA E+ + +A++E ++ E E P EDV E
Sbjct: 2040 ETQKTEGDAQPESDGVEAPEAEEEAQEAEGEVQEAEGEAHPESEDVDAQEAEGEAQPESE 2099
Query: 1346 GVQESFLDANMQKSR--EKIKDKEETELDSEE-EQPSHDTSVVSEQMAGSEDDHEEDSHT 1402
GV+ + QK+ E + + E + +SE E P + E D E ++
Sbjct: 2100 GVEAPEAEGEAQKAEGIEAPETEGEAQPESEGIEAPEAEGEAQPESEGVEAQDAEGEAQP 2159
Query: 1403 KEELIELKEEEEIPHSELDLETVQAVQSLTQEESS--EHEGAYQDCEETLAACQTLQSYT 1460
+ E IE +E EE EL+ + Q ES E A + + L + ++
Sbjct: 2160 ESEGIEAQEAEEEAQPELEGVEAPEAEGEAQPESEGIEAPEAEGEAQPELEGVEAPEAEE 2219
Query: 1461 QADEDPQMSMVEDCHASEHNSPISSVQSHPSQSVRSVSSPNVPALESGYTQISPEQGSLS 1520
+A +P+ VE A P S ++ + SP V +L G ++ + E S
Sbjct: 2220 EAQPEPE--GVETPEAEGEAQPESEGETQGEKK----GSPQV-SLGDGQSEEASESSSPV 2272
Query: 1521 APSMQNMETSPMMDVPSVSDHSQQVVDSGFSDLGSIESTTENYENPSSYDSTMGGSICGN 1580
SP D P SQ G S ++ N DS + G+
Sbjct: 2273 PEDRPTPPPSPGGDTPHQRPGSQ---------TGPSSSRASSWGNCWQKDSE-NDHVLGD 2322
Query: 1581 SSSQSSCSYGGLSSSSSLTQ---SSCVVTQQMASMGS 1614
+ S + S G + T+ S Q+ A +GS
Sbjct: 2323 TRSPDAKSTGTPHAERKATRMYPESSTSEQEEAPLGS 2359
Score = 54.3 bits (129), Expect = 1e-06
Identities = 61/234 (26%), Positives = 91/234 (38%), Gaps = 22/234 (9%)
Query: 1205 QESEETVEPKEDMPLPEERKEEEEMQAEAEEAEEGE--EEDAASSEVPAASPADSSNSPE 1262
++SEE L E +EE E +E EGE +E+A E E
Sbjct: 1278 RDSEEQRASSNLEQLAENTVQEEVQLEETKEGTEGEGLQEEAVQLE-------------E 1324
Query: 1263 TETKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDEDDG 1322
T+T+E EE + EE +++E E Q+ EE + EE E+ E Q + ++ +G
Sbjct: 1325 TKTEEGLQEEGVQ----LEETKETEGEGQQEEEAQLEEIEETGGEGLQEEGVQLEEVKEG 1380
Query: 1323 HLESTKKKELEEQPTREDVKEEPGVQESFLDANMQKSREKIKDKEETELDSEEEQPSHDT 1382
+ + LEE E + EE V L + S K +E + EEE
Sbjct: 1381 PEGGLQGEALEEGLKEEGLPEEGSVHGQELS---EASSPDGKGSQEDDPVQEEEAGRASA 1437
Query: 1383 SVVSEQMAGSEDDHEEDSHTKEELIELKEEEEIPHSELDLETVQAVQSLTQEES 1436
S G+E+ E SH E E + E LE + QE +
Sbjct: 1438 SAEPCPAEGTEEPTEPPSHLSETDPSASERQSGSQLEPGLEKPPGATMMGQEHT 1491
Score = 52.0 bits (123), Expect = 6e-06
Identities = 218/1138 (19%), Positives = 389/1138 (34%), Gaps = 168/1138 (14%)
Query: 787 SEEEEEEAEEGENEEPQCQERELEISVGKSVSHENKEQDSYSVESEKKPEVMAPVSSTRL 846
+ E+E E + E E+ E +V + V E ++ + E E E + T+
Sbjct: 1271 TNEDEAERDSEEQRASSNLEQLAENTVQEEVQLEETKEGT---EGEGLQEEAVQLEETK- 1326
Query: 847 SKQVLPHDSLPANSQPSRRGRWGRKNRKTQERFGDKDSKLLLEETSSAPQEQYG-ECGEK 905
+++ L + + G ++ E + + L EE + + G E G +
Sbjct: 1327 TEEGLQEEGVQLEETKETEGEGQQEEEAQLEEIEETGGEGLQEEGVQLEEVKEGPEGGLQ 1386
Query: 906 SEATQEQYTES---EEQLVASEE---QPSQDGK---PDLPKR-----RLSEGVEPWRGQL 951
EA +E E EE V +E S DGK D P + R S EP +
Sbjct: 1387 GEALEEGLKEEGLPEEGSVHGQELSEASSPDGKGSQEDDPVQEEEAGRASASAEPCPAEG 1446
Query: 952 KKSPEALKCRLTEGSERLPRRYSEGDR---------AVLRGFSESSEEEEEPESPRSSS- 1001
+ P L+E R S A + G + + + + RSSS
Sbjct: 1447 TEEPTEPPSHLSETDPSASERQSGSQLEPGLEKPPGATMMGQEHTQAQPTQGAAERSSSV 1506
Query: 1002 --------PPILTKPTLKR-KKPFL-HRRRRVRKRKHH----NSSVVTETISETTEVLDE 1047
PI LK+ +K FL H V + + ++ ++ + +E + + +
Sbjct: 1507 ACSAALDCDPIWVSVLLKKTEKAFLAHLASAVAELRARWGLQDNDLLDQMAAELQQDVAQ 1566
Query: 1048 PFEDSDSERPMPRLEPTFE--IDEEEEEEDENELFPREYFRRLSSQDVLRCQSSSKRKS- 1104
+DS ++R + +L+ + E E EL + RR + + + S+R
Sbjct: 1567 RLQDS-TKRELQKLQGRAGRMVLEPPREALTGELLLQTQQRRHRLRGLRNLSAFSERTLG 1625
Query: 1105 --------KDEEE------DEESDDADDTPILKPVSLLRKRDVKNSPLEPDTSTPLKKKK 1150
+DE + ++A+ + +RK K SP+ P K
Sbjct: 1626 LGPLSFTLEDEPALSTALGSQLGEEAEGEEFCPCEACVRK---KVSPMSP------KATM 1676
Query: 1151 GWPKGKSRKPIHWKKRPGRKPGFKLSREIMPVSTQACVIEPI----VSIPKAGRKPKIQE 1206
G +G ++ ++ RK G E V+ +P V + G P + +
Sbjct: 1677 GATRGPIKEAFDLQQILQRKRGEHTDGEAAEVAPGKTHTDPTSTRTVQGAEGGLGPGLSQ 1736
Query: 1207 SEETVEPKEDMPLPEERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSNSPETETK 1266
E ++ ++++ EAE +E + +++ ET
Sbjct: 1737 GPGVDEGEDGEGSQRLNRDKDPKLGEAEGDAMAQEREG------------KTHNSETSAG 1784
Query: 1267 EPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDEDDGHLES 1326
E E+E +S E+ E E++ E A D D D
Sbjct: 1785 SELGEAEQEGEGIS--------ERGETGGQGSGHEDNLQGEAAAGGDQDPGQSDGAEGIE 1836
Query: 1327 TKKKELEEQPTREDVKEEPGVQESFLDANMQKSREKIKDKEETELDSEEEQPSHDTSVVS 1386
+ E E QP E V E P + +A + E +D E E + E + S D
Sbjct: 1837 APEAEGEAQPESEGV-EAPEAEGDAQEAEGEAQPES-EDVEAPEAEGEAQPESEDV---- 1890
Query: 1387 EQMAGSEDDHEEDSHTKEELIELKEEEEIPHSELDLE-TVQAVQSLTQEESSEHEGAYQD 1445
E + E+ E E P +E + + ++V++L E E E +
Sbjct: 1891 -----------ETPEAEWEVQPESEGAEAPEAEKEAQPETESVEALETEGEDEPESEGAE 1939
Query: 1446 CEETLAACQTLQSYTQADEDPQMSMVEDCHASEHNSPIS--------SVQSHPSQSVRSV 1497
+E A Q + TQ P+ ++E A E P S V++ ++
Sbjct: 1940 AQEAEEAAQEAEGQTQ----PESEVIESQEAEEEAQPESEDVEALEVEVETQEAEGEAQP 1995
Query: 1498 SSPNVPALES-GYTQISPEQGSLSAPSMQNMETSPMMDVPSVSDHSQQVVDSGFSDLGSI 1556
S +V A E+ G Q + E+ + P +E P S + +Q+V G
Sbjct: 1996 ESEDVEAPEAEGEMQEAEEE---AQPESDGVEAQP----KSEGEEAQEVEGETQKTEGDA 2048
Query: 1557 ESTTENYENPSSYDSTMGG-----SICGNSSSQSSCSYGGLSSSSSLTQSSCVVTQQMAS 1611
+ ++ E P + + G + +S + + +S V +
Sbjct: 2049 QPESDGVEAPEAEEEAQEAEGEVQEAEGEAHPESEDVDAQEAEGEAQPESEGVEAPEAEG 2108
Query: 1612 MGSSCSMMQ----QSSVQPAANCSIKSPQSCVVERPPSNQQQQPPPPPPQQPQPPPPQPQ 1667
++ + QP + I++P++ +P S + QP+ + Q
Sbjct: 2109 EAQKAEGIEAPETEGEAQPESE-GIEAPEAEGEAQPESEGVEAQDAEGEAQPESEGIEAQ 2167
Query: 1668 PAPQPPPPQQQPQQQPQPQPQQPP-------PPPPPQQQPPLSQC---SMNNSFTPAPMI 1717
A + P+ + + P+ + + P P + QP L P P
Sbjct: 2168 EAEEEAQPELEGVEAPEAEGEAQPESEGIEAPEAEGEAQPELEGVEAPEAEEEAQPEPEG 2227
Query: 1718 MEIPESGSTGNISIYERIPGD--------FGAGSYSQPSATFSLAKLQQLTNTIM----D 1765
+E PE+ G+ G G + S + S + T
Sbjct: 2228 VETPEAEGEAQPESEGETQGEKKGSPQVSLGDGQSEEASESSSPVPEDRPTPPPSPGGDT 2287
Query: 1766 PHAMPYSHSPAVTSYATSVSLSNTGLAQLAPSHPLAGT--PQAQATMTPPPNLASTTM 1821
PH P S + +S A+ S N H L T P A++T TP +T M
Sbjct: 2288 PHQRPGSQTGPSSSRAS--SWGNCWQKDSENDHVLGDTRSPDAKSTGTPHAERKATRM 2343
Score = 46.2 bits (108), Expect = 3e-04
Identities = 118/588 (20%), Positives = 199/588 (33%), Gaps = 85/588 (14%)
Query: 782 SNSVVSEEEEEEAEEGENE-EPQCQERELEISVGKSVSHENKEQDSYSVESEKKPE---V 837
S V + E E +A+E E E +P+ ++ E + G++ E+++ ++ E E +PE
Sbjct: 1848 SEGVEAPEAEGDAQEAEGEAQPESEDVEAPEAEGEA-QPESEDVETPEAEWEVQPESEGA 1906
Query: 838 MAPVSSTRLSKQVLPHDSLPANSQ--PSRRGRWGRKNRKT-QERFGDKDSKLLLEETSSA 894
AP + + ++L + P G ++ + QE G + + E+ A
Sbjct: 1907 EAPEAEKEAQPETESVEALETEGEDEPESEGAEAQEAEEAAQEAEGQTQPESEVIESQEA 1966
Query: 895 P-------------------QEQYGECGEKSEATQEQYTESEEQLVASEEQPSQDGKPDL 935
QE GE +SE + E E Q E QP DG
Sbjct: 1967 EEEAQPESEDVEALEVEVETQEAEGEAQPESEDVEAPEAEGEMQEAEEEAQPESDGVEAQ 2026
Query: 936 PKRRLSEGVEPWRGQLKKS-----PEALKCRLTEGSERLPRRYSEGDRAVLRGFSES--- 987
PK E E G+ +K+ PE+ E E E A ES
Sbjct: 2027 PKSEGEEAQEV-EGETQKTEGDAQPESDGVEAPEAEEEAQEAEGEVQEAEGEAHPESEDV 2085
Query: 988 ----SEEEEEPESPRSSSPPILTKPTLKRKKPFLHRRRRVRKRKHHNSSVVTETISETTE 1043
+E E +PES +P + +K + + + + + +
Sbjct: 2086 DAQEAEGEAQPESEGVEAPEAEGEA---QKAEGIEAPETEGEAQPESEGIEAPEAEGEAQ 2142
Query: 1044 VLDEPFEDSDSERPMPRLEPTFEIDEEEEEEDENELFPREYFRRLSSQDVLRCQSSSKRK 1103
E E D+E +P E E +E E+E + L + + ++ +
Sbjct: 2143 PESEGVEAQDAEG---EAQPESEGIEAQEAEEEAQ-------PELEGVEAPEAEGEAQPE 2192
Query: 1104 SKDEEEDEESDDADDTPILKPVSLLRKRDVKNSPLEPDTSTPLKKKKGWPKGKSRKPIHW 1163
S+ E E +A P L+ V + + P TP + + P+ +
Sbjct: 2193 SEGIEAPEAEGEAQ--PELEGVEAPEAEE-EAQPEPEGVETPEAEGEAQPESEGETQGEK 2249
Query: 1164 KKRPGRKPGFKLSREIMPVSTQACVIEPIVSIPKAGRKPKIQESEETVEPKEDMPLPEER 1223
K P G S E S+ + E T P P +R
Sbjct: 2250 KGSPQVSLGDGQSEEASESSSP------------------VPEDRPTPPPSPGGDTPHQR 2291
Query: 1224 KEEEEMQAEAEEAEEGE--EEDAASSEV--PAASP-ADSSNSPETETK------EPEVEE 1272
+ + + + G ++D+ + V SP A S+ +P E K E E
Sbjct: 2292 PGSQTGPSSSRASSWGNCWQKDSENDHVLGDTRSPDAKSTGTPHAERKATRMYPESSTSE 2351
Query: 1273 EEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDED 1320
+EE P S Q E +L+E + + D DD D
Sbjct: 2352 QEEAPLGSRTPEQGASEGYDLQEDQALGSLAPTEAVGRADGFGQDDLD 2399
Score = 40.4 bits (93), Expect = 0.018
Identities = 65/310 (20%), Positives = 115/310 (37%), Gaps = 36/310 (11%)
Query: 1216 DMPLPEERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSNSPETETKEPEVEEEEE 1275
++PL + + E+ E +++ + + A + A ++N E E + EE+
Sbjct: 1229 ELPLKTSNQRPDSRTYESPGDLENQQQCCFPTFLNARACACATNEDEAER-----DSEEQ 1283
Query: 1276 KPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDEDDGHLESTKKKE--LE 1333
+ + EQ Q+E++ ET + + + E+ LE TK +E E
Sbjct: 1284 RASSNLEQLAENTVQEEVQ----------LEETKEGTEGEGLQEEAVQLEETKTEEGLQE 1333
Query: 1334 EQPTREDVKEEPGVQESFLDANMQKSREKIKDKEETELDSEEEQPSHDTSVVSEQMAGSE 1393
E E+ KE G Q+ ++++ EET + +E+ V G +
Sbjct: 1334 EGVQLEETKETEG-------EGQQEEEAQLEEIEETGGEGLQEEGVQLEEVKEGPEGGLQ 1386
Query: 1394 DDHEEDSHTKEELIELKEEEEIPHSELDLETVQAVQSLTQEESSEHEGAYQDCEETLAAC 1453
+ E+ KEE L EE + EL + S + S+ + Q+ E A+
Sbjct: 1387 GEALEEG-LKEE--GLPEEGSVHGQEL------SEASSPDGKGSQEDDPVQEEEAGRASA 1437
Query: 1454 QTLQSYTQADEDPQMSMVEDCHASEHNSPISSVQSHPSQSVRSVSSPNVPALESGYTQIS 1513
+ E+P H SE + S QS P + +TQ
Sbjct: 1438 SAEPCPAEGTEEP---TEPPSHLSETDPSASERQSGSQLEPGLEKPPGATMMGQEHTQAQ 1494
Query: 1514 PEQGSLSAPS 1523
P QG+ S
Sbjct: 1495 PTQGAAERSS 1504
>gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapiens]
Length = 1341
Score = 80.5 bits (197), Expect = 2e-14
Identities = 175/793 (22%), Positives = 288/793 (36%), Gaps = 73/793 (9%)
Query: 1057 PMPRLEPTFEIDEEEEEEDENELFPREYFRRLSSQDVLRCQSSSKRKSKDEEEDEESDDA 1116
P +P +I EE + F ++Y + R + ++ ++ EE ES+D
Sbjct: 117 PHAAFQPNSQIGEEMSQNS----FIKQYLEKQQELLRQRLEREAREAAELEEASAESEDE 172
Query: 1117 DDTP-----ILKP--VSLLRKRDVKNSPLEPDTSTPLKKKKGWPKG-KSRKPIHWKKRPG 1168
P +L P S L + +++ S P S+ + ++KG K RK R
Sbjct: 173 MIHPEGVASLLPPDFQSSLERPELELSRHSPRKSSSISEEKGDSDDEKPRKGERRSSRVR 232
Query: 1169 RKPGFKLSREIMPVSTQACVIEPIVSIP-KAGRKPKIQESEETVEPKEDMPLPEERKEEE 1227
+ KLS P + P ++ +A R K +E EE E +E+ EE +E
Sbjct: 233 QARAAKLSEGSQPAEEEEDQETPSRNLRVRADRNLKTEEEEEEEEEEEEDDEEEEGDDEG 292
Query: 1228 EMQAEAEEAEEGEEEDAASSEVPAASPADSSNS-PETETKEPEVEEEEEK-PRVSEEQRQ 1285
+ EA +E +EE E+P P + + P+T ++E EV E + R EE R+
Sbjct: 293 QKSREAPILKEFKEE---GEEIPRVKPEEMMDERPKTRSQEQEVLERGGRFTRSQEEARK 349
Query: 1286 S----EEEQQELEEPEPEEEEDAAAETAQNDDHDADDEDDGHL-ESTKKKELEEQPTRED 1340
S +++++E++ P EEE+ +++Q + L E KK L P +
Sbjct: 350 SHLARQQQEKEMKTTSPLEEEEREIKSSQGLKEKSKSPSPPRLTEDRKKASLVALPEQTA 409
Query: 1341 VKEEPGVQESFLDANMQKSREKIKDKEETE----------LDSEEEQPSHDTS--VVSE- 1387
+EE +A+ ++ +EE E + DT +VS+
Sbjct: 410 SEEETPPPLLTKEASSPPPHPQLHSEEEIEPMEGPAPPVLIQLSPPNTDADTRELLVSQH 469
Query: 1388 --QMAGSEDDHEEDSHTKEE--LIELKEEEEIPHSELDLETVQAVQSLTQEESSEHEGAY 1443
Q+ G S TK E ++ EE +P + + Q + ES
Sbjct: 470 TVQLVGGLSPLSSPSDTKAESPAEKVPEESVLPLVQKSTLADYSAQKDLEPESDRSAQPL 529
Query: 1444 QDCEETLAACQTLQSYTQADEDPQMSMVEDCHASEHNSPISSV-QSHPSQSVRSVSSPNV 1502
E LA + + + + P + E AS P + QS S S RS SS +
Sbjct: 530 PLKIEELALAKGITE--ECLKQPSLEQKEGRRASHTLLPSHRLKQSADSSSSRSSSSSSS 587
Query: 1503 PALESGYTQISPEQGSLSAPSMQNMETSPMMDVPSVSDHSQQVVDSGFSDLGSIESTTEN 1562
+ + S GS S ++ S DV H+ + ES + +
Sbjct: 588 SSRSRSRSPDS--SGSRSHSPLR----SKQRDVAQARTHANPRGRPKMGSRSTSESRSRS 641
Query: 1563 YENPSSYDSTMGGSICGNSSSQSSCSYGGLSSSSSLTQSSCVVTQQMASMGSSCSMMQQS 1622
S S S+ S SS SY SS + + Q+ C +++
Sbjct: 642 RSRSRSASSNSRKSLSPGVSRDSSTSYTETKDPSSGQEVATPPVPQL----QVCEPKERT 697
Query: 1623 SVQPAANCSIKSPQSCVVERPPS-----NQQQQPPPPPPQQPQPPPPQPQPAPQPPPPQQ 1677
S S S Q+ + +P S Q+ QP P++ + +P A QP +
Sbjct: 698 ST------SSSSVQARRLSQPESAEKHVTQRLQPERGSPKKCEAEEAEPPAATQPQTSET 751
Query: 1678 QPQQQPQPQPQQPPPPPPPQQQPPLSQCSMNNSFTPAPMIM-------EIPESGSTGNIS 1730
Q P+ + + S+ N PM + + PE
Sbjct: 752 QTSHLPESERIHHTVEEKEEVTMDTSENRPENDVPEPPMPIADQVSNDDRPEGSVEDEEK 811
Query: 1731 IYERIPGDFGAGSYSQPSATFSLAKLQQLTNTIMDPHAMPYSHSPAVTSYATSVSLSNTG 1790
+P F S SAT + T + S A T S+S++
Sbjct: 812 KESSLPKSF-KRKISVVSATKGVPAGNSDTEGGQPGRKRRWGASTATTQKKPSISITTES 870
Query: 1791 LAQLAPS-HPLAG 1802
L L P PLAG
Sbjct: 871 LKSLIPDIKPLAG 883
Score = 68.2 bits (165), Expect = 8e-11
Identities = 141/639 (22%), Positives = 224/639 (35%), Gaps = 143/639 (22%)
Query: 1194 SIPKAGRKPKIQESEETVEPKEDMPLPEERKE--EEEMQAEAEEAEEGEEEDAASSE--- 1248
S P A +P Q EE + E+++E + ++ EA EA E EE A S +
Sbjct: 115 STPHAAFQPNSQIGEEMSQNSFIKQYLEKQQELLRQRLEREAREAAELEEASAESEDEMI 174
Query: 1249 ----VPAASPADSSNSPETETKEPEVEEEEEKPR----VSEEQRQSEEEQQELEEPEPEE 1300
V + P D +S E PE+E PR +SEE+ S++E+ E
Sbjct: 175 HPEGVASLLPPDFQSSLE----RPELELSRHSPRKSSSISEEKGDSDDEKPRKGERRSSR 230
Query: 1301 EEDAAAETAQNDDHDADDEDDGHLES------------TKKKELEEQPTREDVKEEPGVQ 1348
A A A++E+D S T+++E EE+ ED +EE G
Sbjct: 231 VRQARAAKLSEGSQPAEEEEDQETPSRNLRVRADRNLKTEEEEEEEEEEEEDDEEEEGDD 290
Query: 1349 ESFLDANMQKSREKIKDKEETELDSE----------EEQPSHDTSVVSEQMAGSEDDHEE 1398
E QKSRE KE E E +E+P + G +
Sbjct: 291 EG------QKSREAPILKEFKEEGEEIPRVKPEEMMDERPKTRSQEQEVLERGGRFTRSQ 344
Query: 1399 DSHTKEELIELKEEEEIPHS---ELDLETVQAVQSLTQEESSEHEGAYQDCEETLAACQT 1455
+ K L ++E+E+ + E + +++ Q L ++ S + + A+
Sbjct: 345 EEARKSHLARQQQEKEMKTTSPLEEEEREIKSSQGLKEKSKSPSPPRLTE-DRKKASLVA 403
Query: 1456 LQSYTQADED----------------PQMSMVEDCHASEHNSPISSVQSHPSQS------ 1493
L T ++E+ PQ+ E+ E +P +Q P +
Sbjct: 404 LPEQTASEEETPPPLLTKEASSPPPHPQLHSEEEIEPMEGPAPPVLIQLSPPNTDADTRE 463
Query: 1494 -------------VRSVSSPNVPALESGYTQISPEQGSLSAPSMQNM-ETSPMMDVPSVS 1539
+ +SSP+ ES ++ PE+ L + + S D+ S
Sbjct: 464 LLVSQHTVQLVGGLSPLSSPSDTKAESPAEKV-PEESVLPLVQKSTLADYSAQKDLEPES 522
Query: 1540 DHSQQVVDSGFSDLGSIESTTEN-YENPS---------------------SYDSTMGGSI 1577
D S Q + +L + TE + PS S DS+ S
Sbjct: 523 DRSAQPLPLKIEELALAKGITEECLKQPSLEQKEGRRASHTLLPSHRLKQSADSSSSRSS 582
Query: 1578 CGNSSSQSSCS----YGGLSSSSSLTQSSCVVTQ-----------QMASMGSSCSMMQQS 1622
+SSS S S G S S L V Q +M S +S S +
Sbjct: 583 SSSSSSSRSRSRSPDSSGSRSHSPLRSKQRDVAQARTHANPRGRPKMGSRSTSESRSRSR 642
Query: 1623 SVQPAANCSIKSPQSCVVER----------PPSNQQQQPPPPPPQQPQPPPP-------- 1664
S +A+ + + S V R PS+ Q+ PP PQ P
Sbjct: 643 SRSRSASSNSRKSLSPGVSRDSSTSYTETKDPSSGQEVATPPVPQLQVCEPKERTSTSSS 702
Query: 1665 --QPQPAPQPPPPQQQPQQQPQPQPQQPPPPPPPQQQPP 1701
Q + QP ++ Q+ QP+ P + +PP
Sbjct: 703 SVQARRLSQPESAEKHVTQRLQPERGSPKKCEAEEAEPP 741
Score = 68.2 bits (165), Expect = 8e-11
Identities = 156/714 (21%), Positives = 257/714 (35%), Gaps = 85/714 (11%)
Query: 783 NSVVSEEEEEEAEEGENEEPQCQERELEISVGKSVSHENKEQDSYSVESEKKPEVMAPVS 842
N EEEEEE EE E++E + + E + S + E KE+ + K E+M
Sbjct: 266 NLKTEEEEEEEEEEEEDDEEEEGDDEGQKSREAPILKEFKEEGE-EIPRVKPEEMMDERP 324
Query: 843 STRLSKQ-VLPHDSLPANSQ-PSRRGRWGR----KNRKT-----QERFGDKDSKLLLEET 891
TR +Q VL SQ +R+ R K KT +E K S+ L E++
Sbjct: 325 KTRSQEQEVLERGGRFTRSQEEARKSHLARQQQEKEMKTTSPLEEEEREIKSSQGLKEKS 384
Query: 892 SSAPQEQYGECGEKSE--ATQEQYTESEEQLVASEEQPSQDGKPDLPKRRLSEGVEPWRG 949
S + E +K+ A EQ T SEE+ P P+ E +EP G
Sbjct: 385 KSPSPPRLTEDRKKASLVALPEQ-TASEEETPPPLLTKEASSPPPHPQLHSEEEIEPMEG 443
Query: 950 QLKKSPEALKCRLTEGSER--LPRRYS---EGDRAVLRGFSESSEEEEEPESPRSSSPPI 1004
L T+ R L +++ G + L S++ E + P S P+
Sbjct: 444 PAPPVLIQLSPPNTDADTRELLVSQHTVQLVGGLSPLSSPSDTKAESPAEKVPEESVLPL 503
Query: 1005 LTKPTL------KRKKPFLHRRRRVRKRKHHNSSVVTETISETTEVLDEPFEDSDSERPM 1058
+ K TL K +P R + K ++ T E L +P
Sbjct: 504 VQKSTLADYSAQKDLEPESDRSAQPLPLKIEELALAK---GITEECLKQP---------- 550
Query: 1059 PRLEPTFEIDEEEEEEDENELFPREYFRRLSSQDVLRCQSSSKRKSKDEEEDEESDDADD 1118
++++E + L P ++ + R SSS S+ +S +
Sbjct: 551 -------SLEQKEGRRASHTLLPSHRLKQSADSSSSRSSSSSSSSSRSRSRSPDSSGSRS 603
Query: 1119 TPILKPVSLLRKRDV---------KNSPLEPDTSTPLKKKKGWPKGKSRKPIHWKK-RPG 1168
L+ ++RDV + P ST + + + +S K PG
Sbjct: 604 HSPLRS----KQRDVAQARTHANPRGRPKMGSRSTSESRSRSRSRSRSASSNSRKSLSPG 659
Query: 1169 --RKPGFKLSREIMPVSTQACVIEPIVSIPKAGRKPKIQESEETVEPKE-DMPLPEERKE 1225
R + P S Q P+ + K + S +V+ + P E+
Sbjct: 660 VSRDSSTSYTETKDPSSGQEVATPPVPQLQVCEPKERTSTSSSSVQARRLSQPESAEKHV 719
Query: 1226 EEEMQAEAEEAE--EGEEEDAASSEVPAASPADSSNSPETETKEPEVEEEEEKPRVSEEQ 1283
+ +Q E + E EE + ++ P S +S+ PE+E VEE+EE + E
Sbjct: 720 TQRLQPERGSPKKCEAEEAEPPAATQPQTSETQTSHLPESERIHHTVEEKEEVTMDTSEN 779
Query: 1284 RQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQPTREDVKE 1343
R E PE A + + +D + ED+ ES+ K + + + V
Sbjct: 780 RP--------ENDVPEPPMPIADQVSNDDRPEGSVEDEEKKESSLPKSFKRKIS--VVSA 829
Query: 1344 EPGVQESFLDANMQKSREKIKDKEETELDSEEEQPSHDTSVVS------EQMAGSE---D 1394
GV D + K + T ++ S T + + +AG E D
Sbjct: 830 TKGVPAGNSDTEGGQPGRKRRWGASTATTQKKPSISITTESLKSLIPDIKPLAGQEAVVD 889
Query: 1395 DHEEDSHTKEELIELKEEEEIPHSELDL-ETVQAVQSLTQEESSEHEGAYQDCE 1447
H +DS E+ E ++ L + TV V +E+ + E ++ E
Sbjct: 890 LHADDSRISEDETERNGDDGTHDKGLKICRTVTQVVPAEGQENGQREEEEEEKE 943
Score = 59.7 bits (143), Expect = 3e-08
Identities = 113/598 (18%), Positives = 211/598 (35%), Gaps = 89/598 (14%)
Query: 788 EEEEEEAEEGENEEPQCQERELEISVGKSVSHENKEQDSYSVESEKKPEVMAPVSSTRLS 847
EE+EE + P+ E + + VS++++ + S VE E+K E P S R
Sbjct: 767 EEKEEVTMDTSENRPENDVPEPPMPIADQVSNDDRPEGS--VEDEEKKESSLPKSFKRKI 824
Query: 848 KQVLPHDSLPANS------QPSRRGRWGRKNRKTQERFGDKDSKLLLEETSSAPQEQYGE 901
V +PA + QP R+ RWG TQ++ + E S +
Sbjct: 825 SVVSATKGVPAGNSDTEGGQPGRKRRWGASTATTQKK---PSISITTESLKSLIPDIKPL 881
Query: 902 CGEKSEATQEQYTESEEQLVASEEQPSQDGKPDLPKRRLSEGVEPWRGQLKKSPEALKCR 961
G+ EA + + + E+ DG D +G++ R + P
Sbjct: 882 AGQ--EAVVDLHADDSRISEDETERNGDDGTHD-------KGLKICRTVTQVVP------ 926
Query: 962 LTEGSERLPRRYSEGDRAVLRGFSESSEEEEEPESPRSSSPPILTKPTLKRKKPFLHRRR 1021
EG E G E EEE+EPE+ P + + L P H +
Sbjct: 927 -AEGQEN--------------GQREEEEEEKEPEAEPPVPPQVSVEVALP--PPAEHEVK 969
Query: 1022 RVRKRKHHNSSVVTETISETTEVLDEPFEDSDSERP----------MPRLEPTFEIDEEE 1071
+V +++ S + +D+P + P + L F + + +
Sbjct: 970 KVTLGDTLTRRSISQQKSGVSITIDDPVRTAQVPSPPRGKISNIVHISNLVRPFTLGQLK 1029
Query: 1072 EEEDENELFPREYF---------------------RRLSSQDVLRCQSSSKRKSKDEEED 1110
E E F R + V QS+ K D E
Sbjct: 1030 ELLGRTGTLVEEAFWIDKIKSHCFVTYSTVEEAVATRTALHGVKWPQSNPKFLCADYAEQ 1089
Query: 1111 EESDDADDTPILKPVSLLRKRDVKNSPLEPDTSTPLKKKKGWPKGKSRKPIHWKKRPGRK 1170
+E D + +P + PL P P++ + P+ + R+ + +
Sbjct: 1090 DELDYHRGLLVDRPSETKTEEQGIPRPLHPPPPPPVQPPQH-PRAEQREQERAVREQWAE 1148
Query: 1171 PGFKLSREIMPVSTQACVIEPIVSIPKAGRKPKIQESEETVEPKEDMPLPEERKEEEEMQ 1230
++ R S + + + P++ + + + +E + KE E+KE+ + +
Sbjct: 1149 REREMERRERTRSEREWDRDKVREGPRSRSRSRDRRRKERAKSKEKK---SEKKEKAQEE 1205
Query: 1231 AEAEEAEEGEEEDAAS----------SEVPAASPADSSNSPETETKEPEVEEEEEKPRVS 1280
A+ ++ + A+ S++ + + E E + E EEEE+K R
Sbjct: 1206 PPAKLLDDLFRKTKAAPCIYWLPLTDSQIVQKEAERAERAKEREKRRKEQEEEEQKEREK 1265
Query: 1281 EEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQPTR 1338
E +R+ + + + E E D E + D D + D + + +E + + T+
Sbjct: 1266 EAERERNRQLEREKRREHSRERDRERERERERDR-GDRDRDRERDRERGRERDRRDTK 1322
Score = 41.6 bits (96), Expect = 0.008
Identities = 113/522 (21%), Positives = 176/522 (33%), Gaps = 100/522 (19%)
Query: 781 VSNSVVSEEEEEEAEEGENEEPQCQERELEISVGKSVSHENKEQDSYSVESEKKPEVMAP 840
++ + + E+ E L+ S S S + S S + P+
Sbjct: 542 ITEECLKQPSLEQKEGRRASHTLLPSHRLKQSADSSSSRSSSSSSSSSRSRSRSPDSSGS 601
Query: 841 VSSTRL-SKQVLPHDSLPANSQPSRRGRWGRKNRKTQERFGDKDSKLLLEETSSAPQEQY 899
S + L SKQ D A + + RGR +R T E S+ ++S
Sbjct: 602 RSHSPLRSKQ---RDVAQARTHANPRGRPKMGSRSTSESRSRSRSRSRSASSNSRKSLSP 658
Query: 900 GECGEKSEATQEQYTESEEQLVASEEQPSQDGKPDLPKRRLSEGVEPWRGQLKKSPEALK 959
G + S + E S Q VA+ P PK R S + + PE+ +
Sbjct: 659 GVSRDSSTSYTETKDPSSGQEVATPPVPQLQVCE--PKERTSTSSSSVQARRLSQPESAE 716
Query: 960 CRLTEGSERLPRRYSEGDRAVLRGFSESSEEEEEPESPRSSSPPILTKP-TLKRKKPFLH 1018
+T+ R E RG + E EE + PP T+P T + + L
Sbjct: 717 KHVTQ------RLQPE------RGSPKKCEAEE-------AEPPAATQPQTSETQTSHLP 757
Query: 1019 RRRRVRKRKHHNSSVVTETISETTEVLDEPFEDSDSERPMPRLEPTFEIDEEEEEEDENE 1078
R+ HH E +T+E + P E+ E PMP I ++ +D E
Sbjct: 758 ESERI----HHTVEEKEEVTMDTSE--NRP-ENDVPEPPMP-------IADQVSNDDRPE 803
Query: 1079 LFPREYFRRLSSQDVLRCQSSSKRKSKDEEEDEESDDADDTPILKPVSLLRKRDVKNSPL 1138
S ++EE +ES P S RK V ++
Sbjct: 804 ------------------------GSVEDEEKKESS--------LPKSFKRKISVVSAT- 830
Query: 1139 EPDTSTPLKKKKGWPKGKSRKPIHWKKRPGRKPGFKLSREIMPVSTQACVIEPIVSIPKA 1198
KG P G S G +PG K +TQ +P +SI
Sbjct: 831 -----------KGVPAGNS-------DTEGGQPGRKRRWGASTATTQK---KPSISITTE 869
Query: 1199 GRKPKIQESEETV--EPKEDMPLPEERKEEEEMQAEAEEAEEGEEED---AASSEVPAAS 1253
K I + + E D+ + R E+E + ++ + + VPA
Sbjct: 870 SLKSLIPDIKPLAGQEAVVDLHADDSRISEDETERNGDDGTHDKGLKICRTVTQVVPAEG 929
Query: 1254 PADSSNSPETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEE 1295
+ E E KEPE E P+VS E + E+++
Sbjct: 930 QENGQREEEEEEKEPEA-EPPVPPQVSVEVALPPPAEHEVKK 970
Score = 39.7 bits (91), Expect = 0.030
Identities = 118/628 (18%), Positives = 222/628 (35%), Gaps = 118/628 (18%)
Query: 895 PQEQYGECGEKSEATQEQYTESEEQLVASEEQPSQDGKPDLPKRRLSEGVEPWRGQLKKS 954
P+E+ +A + ES E+ V QP + PK+ +E EP ++
Sbjct: 693 PKERTSTSSSSVQARRLSQPESAEKHVTQRLQPERGS----PKKCEAEEAEPPAATQPQT 748
Query: 955 PEALKCRLTEGSERLPRRYSEGDRAVLRGFSESSEEEEEPESPRSSSPPILTKP------ 1008
E L E SER+ E + + SE+ E + PE P + +
Sbjct: 749 SETQTSHLPE-SERIHHTVEEKEEVTM-DTSENRPENDVPEPPMPIADQVSNDDRPEGSV 806
Query: 1009 ------------TLKRKKPFLHRRRRV-------------RKRKHHNSSVVTE---TISE 1040
+ KRK + + V RKR+ S+ T+ +IS
Sbjct: 807 EDEEKKESSLPKSFKRKISVVSATKGVPAGNSDTEGGQPGRKRRWGASTATTQKKPSISI 866
Query: 1041 TTEVLDEPFEDSDSERPMPRLEPTFEI--DEEEEEEDENELFPREYFRRLSSQDVLRCQS 1098
TTE L D +P+ E ++ D+ EDE E R + + C++
Sbjct: 867 TTESLKSLIPDI---KPLAGQEAVVDLHADDSRISEDETE---RNGDDGTHDKGLKICRT 920
Query: 1099 -------SSKRKSKDEEEDEESDDADDTPI-----------------LKPVSL---LRKR 1131
+ + EEE+EE + + P+ +K V+L L +R
Sbjct: 921 VTQVVPAEGQENGQREEEEEEKEPEAEPPVPPQVSVEVALPPPAEHEVKKVTLGDTLTRR 980
Query: 1132 DV--KNSPLEPDTSTPLKKKK--GWPKGKSRKPIHWKK--RPGRKPGFKLSREIMPVSTQ 1185
+ + S + P++ + P+GK +H RP F L + +
Sbjct: 981 SISQQKSGVSITIDDPVRTAQVPSPPRGKISNIVHISNLVRP-----FTLGQLKELLGRT 1035
Query: 1186 ACVIEPIVSIPKAGRKPKIQES--EETVEPKEDMP-LPEERKEEEEMQAEAEEAEEGEEE 1242
++E I K + S EE V + + + + + + A+ E +E +
Sbjct: 1036 GTLVEEAFWIDKIKSHCFVTYSTVEEAVATRTALHGVKWPQSNPKFLCADYAEQDELDYH 1095
Query: 1243 DAASSEVPAASPADSSNSPET----------ETKEPEVEEEEEKPRVSEE--QRQSEEEQ 1290
+ P+ + + P + P E+ E++ V E+ +R+ E E+
Sbjct: 1096 RGLLVDRPSETKTEEQGIPRPLHPPPPPPVQPPQHPRAEQREQERAVREQWAEREREMER 1155
Query: 1291 QELEEPEPEEEEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQPTRED---------- 1340
+E E E + D E ++ D +S +KK +++ +E+
Sbjct: 1156 RERTRSEREWDRDKVREGPRSRSRSRDRRRKERAKSKEKKSEKKEKAQEEPPAKLLDDLF 1215
Query: 1341 --VKEEPGVQ-----ESFLDANMQKSREKIKDKEETELDSEEEQPSHDTSVVSEQMAGSE 1393
K P + +S + + E+ K++E+ + EEE+ +
Sbjct: 1216 RKTKAAPCIYWLPLTDSQIVQKEAERAERAKEREKRRKEQEEEEQKEREKEAERERNRQL 1275
Query: 1394 DDHEEDSHTKEELIELKEEEEIPHSELD 1421
+ + H++E E + E E + D
Sbjct: 1276 EREKRREHSRERDRERERERERDRGDRD 1303
Score = 35.0 bits (79), Expect = 0.74
Identities = 25/97 (25%), Positives = 44/97 (45%), Gaps = 8/97 (8%)
Query: 748 RREKLIQDHMAKLQLNLRPVDVDPECLRWTPVIVSNSVVSE--------EEEEEAEEGEN 799
++EK ++ AKL +L C+ W P+ S V E E E+ +E E
Sbjct: 1198 KKEKAQEEPPAKLLDDLFRKTKAAPCIYWLPLTDSQIVQKEAERAERAKEREKRRKEQEE 1257
Query: 800 EEPQCQERELEISVGKSVSHENKEQDSYSVESEKKPE 836
EE + +E+E E + + E + + S + E++ E
Sbjct: 1258 EEQKEREKEAERERNRQLEREKRREHSRERDRERERE 1294
Score = 32.7 bits (73), Expect = 3.7
Identities = 14/33 (42%), Positives = 19/33 (57%), Gaps = 2/33 (6%)
Query: 1674 PPQQQPQQQPQPQPQQPPPPPP--PQQQPPLSQ 1704
P + + ++Q P+P PPPPPP P Q P Q
Sbjct: 1103 PSETKTEEQGIPRPLHPPPPPPVQPPQHPRAEQ 1135
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.127 0.368
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 93,365,699
Number of Sequences: 37866
Number of extensions: 5774636
Number of successful extensions: 183143
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1906
Number of HSP's successfully gapped in prelim test: 2388
Number of HSP's that attempted gapping in prelim test: 42675
Number of HSP's gapped (non-prelim): 58755
length of query: 2004
length of database: 18,247,518
effective HSP length: 117
effective length of query: 1887
effective length of database: 13,817,196
effective search space: 26073048852
effective search space used: 26073048852
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.