Guide to the Human Genome
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Search of human proteins with 110224479

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|110224479 prosaposin isoform c preproprotein [Homo sapiens]
         (526 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|110224479 prosaposin isoform c preproprotein [Homo sapiens]       1083   0.0  
gi|110224476 prosaposin isoform b preproprotein [Homo sapiens]       1078   0.0  
gi|11386147 prosaposin isoform a preproprotein [Homo sapiens]        1073   0.0  
gi|145977198 prosaposin-like protein 1 [Homo sapiens]                 451   e-127
gi|38504667 surfactant, pulmonary-associated protein B [Homo sap...   100   6e-21
gi|33943099 surfactant, pulmonary-associated protein B [Homo sap...   100   6e-21
gi|4502115 acyloxyacyl hydrolase precursor [Homo sapiens]              40   0.004
gi|221219048 transducin-like enhancer protein 2 isoform 2 [Homo ...    37   0.034
gi|21361151 transducin-like enhancer protein 2 isoform 1 [Homo s...    37   0.044
gi|39812027 amino-terminal enhancer of split isoform c [Homo sap...    34   0.38 
gi|5453634 dynein, cytoplasmic, light intermediate polypeptide 2...    34   0.38 
gi|156139127 hypothetical protein LOC80007 [Homo sapiens]              34   0.38 
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]             33   0.49 
gi|194473700 Src homology 3 domain-containing guanine nucleotide...    33   0.49 
gi|39812019 amino-terminal enhancer of split isoform a [Homo sap...    33   0.84 
gi|5706731 amino-terminal enhancer of split isoform b [Homo sapi...    33   0.84 
gi|51873055 fibulin 2 isoform b precursor [Homo sapiens]               32   1.1  
gi|51873053 fibulin 2 isoform a precursor [Homo sapiens]               32   1.1  
gi|41281907 StAR-related lipid transfer (START) domain containin...    32   1.9  
gi|7657671 upstream binding transcription factor, RNA polymerase...    32   1.9  
gi|29788760 diacylglycerol kinase, eta isoform 1 [Homo sapiens]        31   2.4  
gi|29788751 diacylglycerol kinase, eta isoform 2 [Homo sapiens]        31   2.4  
gi|32967605 bromodomain adjacent to zinc finger domain, 1A isofo...    31   2.4  
gi|121583483 phosphatidylinositol-3-phosphate 5-kinase type III ...    31   3.2  
gi|34915994 transducin-like enhancer protein 4 [Homo sapiens]          31   3.2  
gi|7706254 NOP58 ribonucleoprotein homolog [Homo sapiens]              30   4.2  
gi|224831239 integrin alpha M isoform 1 precursor [Homo sapiens]       30   5.4  
gi|7108344 granulysin isoform NKG5 [Homo sapiens]                      30   5.4  
gi|157502222 granulysin isoform 519 [Homo sapiens]                     30   5.4  
gi|88501734 integrin alpha M isoform 2 precursor [Homo sapiens]        30   5.4  

>gi|110224479 prosaposin isoform c preproprotein [Homo sapiens]
          Length = 526

 Score = 1083 bits (2800), Expect = 0.0
 Identities = 526/526 (100%), Positives = 526/526 (100%)

Query: 1   MYALFLLASLLGAALAGPVLGLKECTRGSAVWCQNVKTASDCGAVKHCLQTVWNKPTVKS 60
           MYALFLLASLLGAALAGPVLGLKECTRGSAVWCQNVKTASDCGAVKHCLQTVWNKPTVKS
Sbjct: 1   MYALFLLASLLGAALAGPVLGLKECTRGSAVWCQNVKTASDCGAVKHCLQTVWNKPTVKS 60

Query: 61  LPCDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDI 120
           LPCDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDI
Sbjct: 61  LPCDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDI 120

Query: 121 IKGEMSRPGEVCSALNLCESLQKHLAELNHQKQLESNKIPELDMTEVVAPFMANIPLLLY 180
           IKGEMSRPGEVCSALNLCESLQKHLAELNHQKQLESNKIPELDMTEVVAPFMANIPLLLY
Sbjct: 121 IKGEMSRPGEVCSALNLCESLQKHLAELNHQKQLESNKIPELDMTEVVAPFMANIPLLLY 180

Query: 181 PQDGPRSKPQPKDNGDVCQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPGMADI 240
           PQDGPRSKPQPKDNGDVCQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPGMADI
Sbjct: 181 PQDGPRSKPQPKDNGDVCQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPGMADI 240

Query: 241 CKNYISQYSEIAIQMMMHMDQQPKEICALVGFCDEVKEMPMQTLVPAKVASKNVIPALEL 300
           CKNYISQYSEIAIQMMMHMDQQPKEICALVGFCDEVKEMPMQTLVPAKVASKNVIPALEL
Sbjct: 241 CKNYISQYSEIAIQMMMHMDQQPKEICALVGFCDEVKEMPMQTLVPAKVASKNVIPALEL 300

Query: 301 VEPIKKHEVPAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQ 360
           VEPIKKHEVPAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQ
Sbjct: 301 VEPIKKHEVPAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQ 360

Query: 361 EVVDTYGSSILSILLEEVSPELVCSMLHLCSGTRLPALTVHVTQPKDGGFCEVCKKLVGY 420
           EVVDTYGSSILSILLEEVSPELVCSMLHLCSGTRLPALTVHVTQPKDGGFCEVCKKLVGY
Sbjct: 361 EVVDTYGSSILSILLEEVSPELVCSMLHLCSGTRLPALTVHVTQPKDGGFCEVCKKLVGY 420

Query: 421 LDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYEPVLIEILVEVMDPSFVCLK 480
           LDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYEPVLIEILVEVMDPSFVCLK
Sbjct: 421 LDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYEPVLIEILVEVMDPSFVCLK 480

Query: 481 IGACPSAHKPLLGTEKCIWGPSYWCQNTETAAQCNAVEHCKRHVWN 526
           IGACPSAHKPLLGTEKCIWGPSYWCQNTETAAQCNAVEHCKRHVWN
Sbjct: 481 IGACPSAHKPLLGTEKCIWGPSYWCQNTETAAQCNAVEHCKRHVWN 526


>gi|110224476 prosaposin isoform b preproprotein [Homo sapiens]
          Length = 527

 Score = 1078 bits (2788), Expect = 0.0
 Identities = 526/527 (99%), Positives = 526/527 (99%), Gaps = 1/527 (0%)

Query: 1   MYALFLLASLLGAALAGPVLGLKECTRGSAVWCQNVKTASDCGAVKHCLQTVWNKPTVKS 60
           MYALFLLASLLGAALAGPVLGLKECTRGSAVWCQNVKTASDCGAVKHCLQTVWNKPTVKS
Sbjct: 1   MYALFLLASLLGAALAGPVLGLKECTRGSAVWCQNVKTASDCGAVKHCLQTVWNKPTVKS 60

Query: 61  LPCDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDI 120
           LPCDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDI
Sbjct: 61  LPCDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDI 120

Query: 121 IKGEMSRPGEVCSALNLCESLQKHLAELNHQKQLESNKIPELDMTEVVAPFMANIPLLLY 180
           IKGEMSRPGEVCSALNLCESLQKHLAELNHQKQLESNKIPELDMTEVVAPFMANIPLLLY
Sbjct: 121 IKGEMSRPGEVCSALNLCESLQKHLAELNHQKQLESNKIPELDMTEVVAPFMANIPLLLY 180

Query: 181 PQDGPRSKPQPKDNGDVCQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPGMADI 240
           PQDGPRSKPQPKDNGDVCQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPGMADI
Sbjct: 181 PQDGPRSKPQPKDNGDVCQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPGMADI 240

Query: 241 CKNYISQYSEIAIQMMMHM-DQQPKEICALVGFCDEVKEMPMQTLVPAKVASKNVIPALE 299
           CKNYISQYSEIAIQMMMHM DQQPKEICALVGFCDEVKEMPMQTLVPAKVASKNVIPALE
Sbjct: 241 CKNYISQYSEIAIQMMMHMQDQQPKEICALVGFCDEVKEMPMQTLVPAKVASKNVIPALE 300

Query: 300 LVEPIKKHEVPAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEEC 359
           LVEPIKKHEVPAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEEC
Sbjct: 301 LVEPIKKHEVPAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEEC 360

Query: 360 QEVVDTYGSSILSILLEEVSPELVCSMLHLCSGTRLPALTVHVTQPKDGGFCEVCKKLVG 419
           QEVVDTYGSSILSILLEEVSPELVCSMLHLCSGTRLPALTVHVTQPKDGGFCEVCKKLVG
Sbjct: 361 QEVVDTYGSSILSILLEEVSPELVCSMLHLCSGTRLPALTVHVTQPKDGGFCEVCKKLVG 420

Query: 420 YLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYEPVLIEILVEVMDPSFVCL 479
           YLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYEPVLIEILVEVMDPSFVCL
Sbjct: 421 YLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYEPVLIEILVEVMDPSFVCL 480

Query: 480 KIGACPSAHKPLLGTEKCIWGPSYWCQNTETAAQCNAVEHCKRHVWN 526
           KIGACPSAHKPLLGTEKCIWGPSYWCQNTETAAQCNAVEHCKRHVWN
Sbjct: 481 KIGACPSAHKPLLGTEKCIWGPSYWCQNTETAAQCNAVEHCKRHVWN 527


>gi|11386147 prosaposin isoform a preproprotein [Homo sapiens]
          Length = 524

 Score = 1073 bits (2776), Expect = 0.0
 Identities = 524/526 (99%), Positives = 524/526 (99%), Gaps = 2/526 (0%)

Query: 1   MYALFLLASLLGAALAGPVLGLKECTRGSAVWCQNVKTASDCGAVKHCLQTVWNKPTVKS 60
           MYALFLLASLLGAALAGPVLGLKECTRGSAVWCQNVKTASDCGAVKHCLQTVWNKPTVKS
Sbjct: 1   MYALFLLASLLGAALAGPVLGLKECTRGSAVWCQNVKTASDCGAVKHCLQTVWNKPTVKS 60

Query: 61  LPCDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDI 120
           LPCDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDI
Sbjct: 61  LPCDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDI 120

Query: 121 IKGEMSRPGEVCSALNLCESLQKHLAELNHQKQLESNKIPELDMTEVVAPFMANIPLLLY 180
           IKGEMSRPGEVCSALNLCESLQKHLAELNHQKQLESNKIPELDMTEVVAPFMANIPLLLY
Sbjct: 121 IKGEMSRPGEVCSALNLCESLQKHLAELNHQKQLESNKIPELDMTEVVAPFMANIPLLLY 180

Query: 181 PQDGPRSKPQPKDNGDVCQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPGMADI 240
           PQDGPRSKPQPKDNGDVCQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPGMADI
Sbjct: 181 PQDGPRSKPQPKDNGDVCQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPGMADI 240

Query: 241 CKNYISQYSEIAIQMMMHMDQQPKEICALVGFCDEVKEMPMQTLVPAKVASKNVIPALEL 300
           CKNYISQYSEIAIQMMMHM  QPKEICALVGFCDEVKEMPMQTLVPAKVASKNVIPALEL
Sbjct: 241 CKNYISQYSEIAIQMMMHM--QPKEICALVGFCDEVKEMPMQTLVPAKVASKNVIPALEL 298

Query: 301 VEPIKKHEVPAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQ 360
           VEPIKKHEVPAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQ
Sbjct: 299 VEPIKKHEVPAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQ 358

Query: 361 EVVDTYGSSILSILLEEVSPELVCSMLHLCSGTRLPALTVHVTQPKDGGFCEVCKKLVGY 420
           EVVDTYGSSILSILLEEVSPELVCSMLHLCSGTRLPALTVHVTQPKDGGFCEVCKKLVGY
Sbjct: 359 EVVDTYGSSILSILLEEVSPELVCSMLHLCSGTRLPALTVHVTQPKDGGFCEVCKKLVGY 418

Query: 421 LDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYEPVLIEILVEVMDPSFVCLK 480
           LDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYEPVLIEILVEVMDPSFVCLK
Sbjct: 419 LDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYEPVLIEILVEVMDPSFVCLK 478

Query: 481 IGACPSAHKPLLGTEKCIWGPSYWCQNTETAAQCNAVEHCKRHVWN 526
           IGACPSAHKPLLGTEKCIWGPSYWCQNTETAAQCNAVEHCKRHVWN
Sbjct: 479 IGACPSAHKPLLGTEKCIWGPSYWCQNTETAAQCNAVEHCKRHVWN 524


>gi|145977198 prosaposin-like protein 1 [Homo sapiens]
          Length = 521

 Score =  451 bits (1160), Expect = e-127
 Identities = 236/534 (44%), Positives = 334/534 (62%), Gaps = 38/534 (7%)

Query: 3   ALFLLASLLGAALAGPVLGLKECTRGSAVWCQNVKTASDCGAVKHCLQTVWNKPTVKSLP 62
           AL LL SLLGA  A P  G +EC +GS VWCQ+++TA+ CGAV +C   VWNKPT KSLP
Sbjct: 4   ALLLLPSLLGATRASPTSGPQECAKGSTVWCQDLQTAARCGAVGYCQGAVWNKPTAKSLP 63

Query: 63  CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 122
           CD+C+D+  AAG+ L  +ATE +IL  + KTC+WLP    SA CK +VD++   IL +++
Sbjct: 64  CDVCQDIAAAAGNGLNPDATESDILALVMKTCEWLPSQESSAGCKWMVDAHSSAILSMLR 123

Query: 123 GEM-SRPGEVCSALNLCESLQKHLAELNHQKQLESNKIPELDMTEVVAPFMANIPLLLYP 181
           G   S P +VC+AL+LCE LQ+HLA L          + + D  E VAPFMAN PL  +P
Sbjct: 124 GAPDSAPAQVCTALSLCEPLQRHLATLR--------PLSKEDTFEAVAPFMANGPLTFHP 175

Query: 182 QDGPRSKPQPKDNGDVCQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPGMADIC 241
           +  P         G +CQDC++ V+ +Q AVR+N T       +++E+C+ LGPG+A +C
Sbjct: 176 RQAPE--------GALCQDCVRQVSRLQEAVRSNLTLADL---NIQEQCESLGPGLAVLC 224

Query: 242 KNYISQYSEIAIQMMMHMDQQPKEICALVGFCDEVKEMPMQTLVPAKVASKNVIPALELV 301
           KNY+ Q+   A Q +  +   P+E+C   GFC+E+      T    +V + + +P+LEL 
Sbjct: 225 KNYLFQFFVPADQALRLLP--PQELCRKGGFCEELGAPARLT----QVVAMDGVPSLELG 278

Query: 302 EPIKKHEVPAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQE 361
            P K+ E+  K+ V CEVC  +V+++   + +N +E  I  A +++CS +P S+++EC  
Sbjct: 279 LPRKQSEMQMKAGVTCEVCMNVVQKLDHWLMSNSSELMITHALERVCSVMPASITKECII 338

Query: 362 VVDTYGSSILSILLEEVSPELVCSMLHLCSGTRLPALTVH-----VTQPK-----DGGFC 411
           +VDTY  S++  L+ +++PE VC  + LC G R  A  VH     V  P+      G FC
Sbjct: 339 LVDTYSPSLVQ-LVAKITPEKVCKFIRLC-GNRRRARAVHDAYAIVPSPEWDAENQGSFC 396

Query: 412 EVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYEPVLIEILVEV 471
             CK+L+     NLE  STK++IL A + GCS LP PY  QC  FV +YEPVLIE L ++
Sbjct: 397 NGCKRLLTVSSHNLESKSTKRDILVAFKGGCSILPLPYMIQCKHFVTQYEPVLIESLKDM 456

Query: 472 MDPSFVCLKIGACPSAHKPLLGTEKCIWGPSYWCQNTETAAQCNAVEHCKRHVW 525
           MDP  VC K+GAC     PLLGT++C  GPS+WC++ E A  CNAV+HC++HVW
Sbjct: 457 MDPVAVCKKVGACHGPRTPLLGTDQCALGPSFWCRSQEAAKLCNAVQHCQKHVW 510



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 17/37 (45%), Positives = 25/37 (67%)

Query: 490 PLLGTEKCIWGPSYWCQNTETAAQCNAVEHCKRHVWN 526
           P  G ++C  G + WCQ+ +TAA+C AV +C+  VWN
Sbjct: 19  PTSGPQECAKGSTVWCQDLQTAARCGAVGYCQGAVWN 55



 Score = 42.7 bits (99), Expect = 8e-04
 Identities = 15/38 (39%), Positives = 24/38 (63%)

Query: 18  PVLGLKECTRGSAVWCQNVKTASDCGAVKHCLQTVWNK 55
           P+LG  +C  G + WC++ + A  C AV+HC + VW +
Sbjct: 475 PLLGTDQCALGPSFWCRSQEAAKLCNAVQHCQKHVWKE 512


>gi|38504667 surfactant, pulmonary-associated protein B [Homo
           sapiens]
          Length = 381

 Score = 99.8 bits (247), Expect = 6e-21
 Identities = 91/411 (22%), Positives = 164/411 (39%), Gaps = 53/411 (12%)

Query: 2   YALFLLASLLGAALAGPVLGLKECTRGSAVWCQNVKTASDCGAVKHCLQTVWNKPTVKSL 61
           + L LL +L G   A        C +G   WCQ+++ A  C A+ HCLQ VW       L
Sbjct: 9   WLLLLLPTLCGPGTAAWTTSSLACAQGPEFWCQSLEQALQCRALGHCLQEVWGHVGADDL 68

Query: 62  PCDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDII 121
            C  C+D+V     M K+   ++ +  +LE+ C+ LP   +   C +++D Y P+++D  
Sbjct: 69  -CQECEDIVHILNKMAKEAIFQDTMRKFLEQECNVLPLKLLMPQCNQVLDDYFPLVIDYF 127

Query: 122 KGEMSRPGEVCSALNLCESLQKHLAELNHQKQLESNKIPELDMTEVVAPFMANIPLLLYP 181
           + +    G +C  L LC+S Q        Q+   S+ +P+     +  P +  + L + P
Sbjct: 128 QNQTDSNG-ICMHLGLCKSRQPE----PEQEPGMSDPLPKPLRDPLPDPLLDKLVLPVLP 182

Query: 182 -----QDGPRSKPQPKDNGDV----CQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDR 232
                + GP ++   +    +    C  C  ++  IQ  +        AL   V + C  
Sbjct: 183 GALQARPGPHTQDLSEQQFPIPLPYCWLCRALIKRIQAMIPKG-----ALAVAVAQVCRV 237

Query: 233 LGPGMADICKNYISQYSEIAIQMMMHMDQQPKEICALVGFCDEVKEMPMQTLVPAKVASK 292
           +      IC+    +YS I +  ++     P+ +C LV  C       M      +  + 
Sbjct: 238 VPLVAGGICQCLAERYSVILLDTLLGR-MLPQLVCRLVLRCS------MDDSAGPRSPTG 290

Query: 293 NVIPALELVEPIKKHEVPAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMC--SK 350
             +P                 D  C +C  +  +       N +E+ I  A  + C  S 
Sbjct: 291 EWLP----------------RDSECHLCMSVTTQA-----GNSSEQAIPQAMLQACVGSW 329

Query: 351 LPKSLSEECQEVVDTYGSSILSILLEEVSPELVCSMLHLCSGTRLPALTVH 401
           L +   E+C++ V+ +   +L+++         C  L +C     P   +H
Sbjct: 330 LDR---EKCKQFVEQHTPQLLTLVPRGWDAHTTCQALGVCGTMSSPLQCIH 377



 Score = 70.9 bits (172), Expect = 3e-12
 Identities = 74/334 (22%), Positives = 134/334 (40%), Gaps = 49/334 (14%)

Query: 196 DVCQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPGMA-DICKNYISQYSEIAIQ 254
           D+CQ+C  +V  I   +   + F   + + +++EC+ L   +    C   +  Y  + I 
Sbjct: 67  DLCQECEDIV-HILNKMAKEAIFQDTMRKFLEQECNVLPLKLLMPQCNQVLDDYFPLVID 125

Query: 255 MMMHMDQQPKEICALVGFC-------------DEVKEMPMQTLVPAKVASKNVIPALELV 301
              +       IC  +G C              +    P++  +P  +  K V+P L   
Sbjct: 126 YFQNQTDS-NGICMHLGLCKSRQPEPEQEPGMSDPLPKPLRDPLPDPLLDKLVLPVLP-- 182

Query: 302 EPIKKHEVPAKSDV----------YCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKL 351
             ++    P   D+          YC +C  L+K +  +I        +  A  ++C  +
Sbjct: 183 GALQARPGPHTQDLSEQQFPIPLPYCWLCRALIKRIQAMIPKGA----LAVAVAQVCRVV 238

Query: 352 PKSLSEECQEVVDTYGSSILSILLEEVSPELVCSMLHLCS--GTRLPALTVHVTQPKDGG 409
           P      CQ + + Y   +L  LL  + P+LVC ++  CS   +  P        P+D  
Sbjct: 239 PLVAGGICQCLAERYSVILLDTLLGRMLPQLVCRLVLRCSMDDSAGPRSPTGEWLPRDSE 298

Query: 410 FCEVCKKLVGYLDRNLEKNSTKQEILAALEKGC--SFLPDPYQKQCDQFVAEYEPVLIEI 467
            C +C  +          NS++Q I  A+ + C  S+L    +++C QFV ++ P L+ +
Sbjct: 299 -CHLCMSVT-----TQAGNSSEQAIPQAMLQACVGSWLD---REKCKQFVEQHTPQLLTL 349

Query: 468 LVEVMDPSFVCLKIGACPSAHKPLLGTEKCIWGP 501
           +    D    C  +G C +   PL    +CI  P
Sbjct: 350 VPRGWDAHTTCQALGVCGTMSSPL----QCIHSP 379



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 15/29 (51%), Positives = 19/29 (65%)

Query: 497 CIWGPSYWCQNTETAAQCNAVEHCKRHVW 525
           C  GP +WCQ+ E A QC A+ HC + VW
Sbjct: 32  CAQGPEFWCQSLEQALQCRALGHCLQEVW 60


>gi|33943099 surfactant, pulmonary-associated protein B [Homo
           sapiens]
          Length = 381

 Score = 99.8 bits (247), Expect = 6e-21
 Identities = 91/411 (22%), Positives = 164/411 (39%), Gaps = 53/411 (12%)

Query: 2   YALFLLASLLGAALAGPVLGLKECTRGSAVWCQNVKTASDCGAVKHCLQTVWNKPTVKSL 61
           + L LL +L G   A        C +G   WCQ+++ A  C A+ HCLQ VW       L
Sbjct: 9   WLLLLLPTLCGPGTAAWTTSSLACAQGPEFWCQSLEQALQCRALGHCLQEVWGHVGADDL 68

Query: 62  PCDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDII 121
            C  C+D+V     M K+   ++ +  +LE+ C+ LP   +   C +++D Y P+++D  
Sbjct: 69  -CQECEDIVHILNKMAKEAIFQDTMRKFLEQECNVLPLKLLMPQCNQVLDDYFPLVIDYF 127

Query: 122 KGEMSRPGEVCSALNLCESLQKHLAELNHQKQLESNKIPELDMTEVVAPFMANIPLLLYP 181
           + +    G +C  L LC+S Q        Q+   S+ +P+     +  P +  + L + P
Sbjct: 128 QNQTDSNG-ICMHLGLCKSRQPE----PEQEPGMSDPLPKPLRDPLPDPLLDKLVLPVLP 182

Query: 182 -----QDGPRSKPQPKDNGDV----CQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDR 232
                + GP ++   +    +    C  C  ++  IQ  +        AL   V + C  
Sbjct: 183 GALQARPGPHTQDLSEQQFPIPLPYCWLCRALIKRIQAMIPKG-----ALAVAVAQVCRV 237

Query: 233 LGPGMADICKNYISQYSEIAIQMMMHMDQQPKEICALVGFCDEVKEMPMQTLVPAKVASK 292
           +      IC+    +YS I +  ++     P+ +C LV  C       M      +  + 
Sbjct: 238 VPLVAGGICQCLAERYSVILLDTLLGR-MLPQLVCRLVLRCS------MDDSAGPRSPTG 290

Query: 293 NVIPALELVEPIKKHEVPAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMC--SK 350
             +P                 D  C +C  +  +       N +E+ I  A  + C  S 
Sbjct: 291 EWLP----------------RDSECHLCMSVTTQA-----GNSSEQAIPQAMLQACVGSW 329

Query: 351 LPKSLSEECQEVVDTYGSSILSILLEEVSPELVCSMLHLCSGTRLPALTVH 401
           L +   E+C++ V+ +   +L+++         C  L +C     P   +H
Sbjct: 330 LDR---EKCKQFVEQHTPQLLTLVPRGWDAHTTCQALGVCGTMSSPLQCIH 377



 Score = 70.9 bits (172), Expect = 3e-12
 Identities = 74/334 (22%), Positives = 134/334 (40%), Gaps = 49/334 (14%)

Query: 196 DVCQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPGMA-DICKNYISQYSEIAIQ 254
           D+CQ+C  +V  I   +   + F   + + +++EC+ L   +    C   +  Y  + I 
Sbjct: 67  DLCQECEDIV-HILNKMAKEAIFQDTMRKFLEQECNVLPLKLLMPQCNQVLDDYFPLVID 125

Query: 255 MMMHMDQQPKEICALVGFC-------------DEVKEMPMQTLVPAKVASKNVIPALELV 301
              +       IC  +G C              +    P++  +P  +  K V+P L   
Sbjct: 126 YFQNQTDS-NGICMHLGLCKSRQPEPEQEPGMSDPLPKPLRDPLPDPLLDKLVLPVLP-- 182

Query: 302 EPIKKHEVPAKSDV----------YCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKL 351
             ++    P   D+          YC +C  L+K +  +I        +  A  ++C  +
Sbjct: 183 GALQARPGPHTQDLSEQQFPIPLPYCWLCRALIKRIQAMIPKGA----LAVAVAQVCRVV 238

Query: 352 PKSLSEECQEVVDTYGSSILSILLEEVSPELVCSMLHLCS--GTRLPALTVHVTQPKDGG 409
           P      CQ + + Y   +L  LL  + P+LVC ++  CS   +  P        P+D  
Sbjct: 239 PLVAGGICQCLAERYSVILLDTLLGRMLPQLVCRLVLRCSMDDSAGPRSPTGEWLPRDSE 298

Query: 410 FCEVCKKLVGYLDRNLEKNSTKQEILAALEKGC--SFLPDPYQKQCDQFVAEYEPVLIEI 467
            C +C  +          NS++Q I  A+ + C  S+L    +++C QFV ++ P L+ +
Sbjct: 299 -CHLCMSVT-----TQAGNSSEQAIPQAMLQACVGSWLD---REKCKQFVEQHTPQLLTL 349

Query: 468 LVEVMDPSFVCLKIGACPSAHKPLLGTEKCIWGP 501
           +    D    C  +G C +   PL    +CI  P
Sbjct: 350 VPRGWDAHTTCQALGVCGTMSSPL----QCIHSP 379



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 15/29 (51%), Positives = 19/29 (65%)

Query: 497 CIWGPSYWCQNTETAAQCNAVEHCKRHVW 525
           C  GP +WCQ+ E A QC A+ HC + VW
Sbjct: 32  CAQGPEFWCQSLEQALQCRALGHCLQEVW 60


>gi|4502115 acyloxyacyl hydrolase precursor [Homo sapiens]
          Length = 575

 Score = 40.4 bits (93), Expect = 0.004
 Identities = 22/77 (28%), Positives = 41/77 (53%), Gaps = 6/77 (7%)

Query: 317 CEVCEFLVKEVTKLID-NNKTEKEILDAFDKMCSKLPKSL--SEECQEVVDTYGSSILSI 373
           C  C  +V  + +L   +N T   +  + +++CS LP+ L     C  V+D +GS I+ +
Sbjct: 41  CVGCVLVVSVIEQLAQVHNST---VQASMERLCSYLPEKLFLKTTCYLVIDKFGSDIIKL 97

Query: 374 LLEEVSPELVCSMLHLC 390
           L  +++ ++VC  L  C
Sbjct: 98  LSADMNADVVCHTLEFC 114



 Score = 32.7 bits (73), Expect = 0.84
 Identities = 25/108 (23%), Positives = 48/108 (44%), Gaps = 7/108 (6%)

Query: 181 PQDGPRSKPQPKDNGDVCQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPG--MA 238
           P +  +S+P    NG  C  C+ +V+ I+   + +++ VQA +E +   C  L     + 
Sbjct: 25  PANDDQSRPS-LSNGHTCVGCVLVVSVIEQLAQVHNSTVQASMERL---CSYLPEKLFLK 80

Query: 239 DICKNYISQYSEIAIQMMMHMDQQPKEICALVGFCDEVKEMPMQTLVP 286
             C   I ++    I+ ++  D     +C  + FC +    P+  L P
Sbjct: 81  TTCYLVIDKFGSDIIK-LLSADMNADVVCHTLEFCKQNTGQPLCHLYP 127


>gi|221219048 transducin-like enhancer protein 2 isoform 2 [Homo
           sapiens]
          Length = 706

 Score = 37.4 bits (85), Expect = 0.034
 Identities = 32/141 (22%), Positives = 64/141 (45%), Gaps = 16/141 (11%)

Query: 182 QDGPRSKPQ-PKDNGDVCQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPGMADI 240
           QD P S  Q P  +G   +  I  + D    ++    F+QA    +K EC++L     ++
Sbjct: 13  QDSPASGLQTPLQSGQPFKFSILEICD---RIKEEFQFLQAQYHSLKLECEKLASEKTEM 69

Query: 241 CKNYISQYSEIAIQMMMHMDQQPKEICALVGFCDEV--------KEMPMQTLVPAK---V 289
            ++Y+  Y E++  + + M +Q + +  L G C ++        ++  +Q +  AK   V
Sbjct: 70  QRHYV-MYYEMSYGLNIEMHKQAEIVKRLSGICAQIIPFLTQEHQQQVLQAVERAKQVTV 128

Query: 290 ASKNVIPALELVEPIKKHEVP 310
              N +   + ++P+  H  P
Sbjct: 129 GELNSLIGQQQLQPLSHHAPP 149


>gi|21361151 transducin-like enhancer protein 2 isoform 1 [Homo
           sapiens]
          Length = 743

 Score = 37.0 bits (84), Expect = 0.044
 Identities = 30/142 (21%), Positives = 65/142 (45%), Gaps = 17/142 (11%)

Query: 179 LYPQDGPRSKPQPKDNGDVCQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPGMA 238
           +YPQ      P P  +G   +  I  + D    ++    F+QA    +K EC++L     
Sbjct: 1   MYPQG---RHPTPLQSGQPFKFSILEICD---RIKEEFQFLQAQYHSLKLECEKLASEKT 54

Query: 239 DICKNYISQYSEIAIQMMMHMDQQPKEICALVGFCDEV--------KEMPMQTLVPAKVA 290
           ++ ++Y+  Y E++  + + M +Q + +  L G C ++        ++  +Q +  AK  
Sbjct: 55  EMQRHYV-MYYEMSYGLNIEMHKQAEIVKRLSGICAQIIPFLTQEHQQQVLQAVERAKQV 113

Query: 291 SKNVIPAL--ELVEPIKKHEVP 310
           +   + +L  + ++P+  H  P
Sbjct: 114 TVGELNSLIGQQLQPLSHHAPP 135


>gi|39812027 amino-terminal enhancer of split isoform c [Homo
           sapiens]
          Length = 196

 Score = 33.9 bits (76), Expect = 0.38
 Identities = 28/129 (21%), Positives = 60/129 (46%), Gaps = 9/129 (6%)

Query: 189 PQPKDNGD--VCQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPGMADICKNYIS 246
           PQ + +G   + Q      +D    ++     +QA    +K ECD+L    +++ ++Y+ 
Sbjct: 4   PQSRHSGSSHLPQQLKFTTSDSCDRIKDEFQLLQAQYHSLKLECDKLASEKSEMQRHYV- 62

Query: 247 QYSEIAIQMMMHMDQQPKEICALVGFCDEV-----KEMPMQTLVPAKVASKNVIPAL-EL 300
            Y E++  + + M +Q + +  L G C +V     +E   Q L   + A +   P L  +
Sbjct: 63  MYYEMSYGLNIEMHKQAEIVKRLNGICAQVLPYLSQEHQQQVLGAIERAKQVTAPELNSI 122

Query: 301 VEPIKKHEV 309
           +  ++ H++
Sbjct: 123 IRQLQAHQL 131


>gi|5453634 dynein, cytoplasmic, light intermediate polypeptide 2
           [Homo sapiens]
          Length = 492

 Score = 33.9 bits (76), Expect = 0.38
 Identities = 25/77 (32%), Positives = 38/77 (49%), Gaps = 8/77 (10%)

Query: 114 LPVILDIIKGEMSRPGEVCSALNLCESLQKHLAELNHQKQLESNKIPELDMTEVVAPFMA 173
           LP  L I   +MSRP  V       ESLQK  + L  ++ ++  KIP   M E+   F+ 
Sbjct: 128 LPETLVIFVADMSRPWTVM------ESLQKWASVL--REHIDKMKIPPEKMRELERKFVK 179

Query: 174 NIPLLLYPQDGPRSKPQ 190
           +    + P++G +  PQ
Sbjct: 180 DFQDYMEPEEGCQGSPQ 196


>gi|156139127 hypothetical protein LOC80007 [Homo sapiens]
          Length = 445

 Score = 33.9 bits (76), Expect = 0.38
 Identities = 29/119 (24%), Positives = 52/119 (43%), Gaps = 23/119 (19%)

Query: 312 KSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSK---LPKSLSEECQEVVDTYGS 368
           ++D+   +  FL K+V+   ++N    E+L     +CS+   L      ECQE +  +G 
Sbjct: 305 ENDLKNAMASFLPKKVSD--NSNIPNSELLPFLQNLCSQVNHLHVGNKTECQENITKHGE 362

Query: 369 SILSILLEEVSPELVCSMLHLCSGTRLPALTVHVTQPKDGGFCEVCKKLVGYLDRNLEK 427
            IL + +EE S   +CS L       +  +                KKL+ Y+D+ + +
Sbjct: 363 RILGVGMEEQS---ICSYLEKILSKNMELME---------------KKLMDYIDQRIHE 403


>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
          Length = 1411

 Score = 33.5 bits (75), Expect = 0.49
 Identities = 47/244 (19%), Positives = 102/244 (41%), Gaps = 19/244 (7%)

Query: 140 SLQKHLAELNHQKQLESNKIPELDMTEVVAPFMANIPLLLYPQDGPRSKPQPKDNG-DVC 198
           SL+  + ELN Q      K+ +LD+        A   LLL  +    ++     N  D  
Sbjct: 618 SLETSVNELNSQLNESKEKVSQLDI-----QIKAKTELLLSAEAAKTAQRADLQNHLDTA 672

Query: 199 QDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPGMADICKNYISQYSEIAIQMMMH 258
           Q+ +Q        + T    V A ++  +E C +L        ++++ +Y E  + +   
Sbjct: 673 QNALQDKQQELNKITTQLDQVTAKLQDKQEHCSQL--------ESHLKEYKEKYLSLEQK 724

Query: 259 MDQQPKEICALVGFCDEV---KEMPMQTLVPAKVASKNV-IPALELVEPIK-KHEVPAKS 313
            ++   +I  L     EV   KE  +Q L   +  + ++ + A EL + ++ + E+ + +
Sbjct: 725 TEELEGQIKKLEADSLEVKASKEQALQDLQQQRQLNTDLELRATELSKQLEMEKEIVSST 784

Query: 314 DVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSILSI 373
            +  +     ++ + + +   + EK+IL    +  S+  K   EE    + T  + +  +
Sbjct: 785 RLDLQKKSEALESIKQKLTKQEEEKQILKQDFETLSQETKIQHEELNNRIQTTVTELQKV 844

Query: 374 LLEE 377
            +E+
Sbjct: 845 KMEK 848


>gi|194473700 Src homology 3 domain-containing guanine nucleotide
           exchange factor [Homo sapiens]
          Length = 871

 Score = 33.5 bits (75), Expect = 0.49
 Identities = 28/136 (20%), Positives = 62/136 (45%), Gaps = 7/136 (5%)

Query: 196 DVCQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPGMADICKNYISQYSEIAIQM 255
           DVC+   +   +++ A   N+ F+  + + V++            C N +  Y +  +Q 
Sbjct: 489 DVCEASKKFFIELE-ARHQNNIFIDDISDIVEKHTASTFDPYVKYCTNEV--YQQRTLQK 545

Query: 256 MMHMDQQPKEICALVGFCDEVKEMPMQTLVPAKVASKNVIPALELVEPIKKHEVPAKSDV 315
           ++  +   KE+ + +   ++ + +PM + +   +     +  L L+      + P  S  
Sbjct: 546 LLATNPSFKEVLSRIESHEDCRNLPMISFL---ILPMQRVTRLPLLMDTICQKTPKDSPK 602

Query: 316 YCEVCEFLVKEVTKLI 331
           Y EVC+  +KEV+KL+
Sbjct: 603 Y-EVCKRALKEVSKLV 617


>gi|39812019 amino-terminal enhancer of split isoform a [Homo
           sapiens]
          Length = 264

 Score = 32.7 bits (73), Expect = 0.84
 Identities = 28/139 (20%), Positives = 62/139 (44%), Gaps = 8/139 (5%)

Query: 178 LLYPQDGPRSKPQPKDNGDVCQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPGM 237
           L + + G R     + +  + Q      +D    ++     +QA    +K ECD+L    
Sbjct: 62  LFFDRWGNRGPAGCRGSSHLPQQLKFTTSDSCDRIKDEFQLLQAQYHSLKLECDKLASEK 121

Query: 238 ADICKNYISQYSEIAIQMMMHMDQQPKEICALVGFCDEV-----KEMPMQTLVPAKVASK 292
           +++ ++Y+  Y E++  + + M +Q + +  L G C +V     +E   Q L   + A +
Sbjct: 122 SEMQRHYV-MYYEMSYGLNIEMHKQAEIVKRLNGICAQVLPYLSQEHQQQVLGAIERAKQ 180

Query: 293 NVIPALELV--EPIKKHEV 309
              P L  +  + ++ H++
Sbjct: 181 VTAPELNSIIRQQLQAHQL 199


>gi|5706731 amino-terminal enhancer of split isoform b [Homo
           sapiens]
          Length = 197

 Score = 32.7 bits (73), Expect = 0.84
 Identities = 28/130 (21%), Positives = 60/130 (46%), Gaps = 10/130 (7%)

Query: 189 PQPKDNGD--VCQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPGMADICKNYIS 246
           PQ + +G   + Q      +D    ++     +QA    +K ECD+L    +++ ++Y+ 
Sbjct: 4   PQSRHSGSSHLPQQLKFTTSDSCDRIKDEFQLLQAQYHSLKLECDKLASEKSEMQRHYV- 62

Query: 247 QYSEIAIQMMMHMDQQPKEICALVGFCDEV-----KEMPMQTLVPAKVASKNVIPALELV 301
            Y E++  + + M +Q + +  L G C +V     +E   Q L   + A +   P L  +
Sbjct: 63  MYYEMSYGLNIEMHKQAEIVKRLNGICAQVLPYLSQEHQQQVLGAIERAKQVTAPELNSI 122

Query: 302 --EPIKKHEV 309
             + ++ H++
Sbjct: 123 IRQQLQAHQL 132


>gi|51873055 fibulin 2 isoform b precursor [Homo sapiens]
          Length = 1184

 Score = 32.3 bits (72), Expect = 1.1
 Identities = 15/42 (35%), Positives = 21/42 (50%), Gaps = 2/42 (4%)

Query: 479 LKIGACPSAHKPLLGTEKCIWGPSYWCQNTETAAQCNAVEHC 520
           LK G C    +  +GT  C   P + CQNT+ +  C A + C
Sbjct: 757 LKDGECEDVDECAMGTHTC--QPGFLCQNTKGSFYCQARQRC 796


>gi|51873053 fibulin 2 isoform a precursor [Homo sapiens]
          Length = 1231

 Score = 32.3 bits (72), Expect = 1.1
 Identities = 15/42 (35%), Positives = 21/42 (50%), Gaps = 2/42 (4%)

Query: 479 LKIGACPSAHKPLLGTEKCIWGPSYWCQNTETAAQCNAVEHC 520
           LK G C    +  +GT  C   P + CQNT+ +  C A + C
Sbjct: 804 LKDGECEDVDECAMGTHTC--QPGFLCQNTKGSFYCQARQRC 843


>gi|41281907 StAR-related lipid transfer (START) domain containing
           13 isoform beta [Homo sapiens]
          Length = 1105

 Score = 31.6 bits (70), Expect = 1.9
 Identities = 21/96 (21%), Positives = 35/96 (36%), Gaps = 5/96 (5%)

Query: 63  CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 122
           C  CKD V       + N T +   +  ++ CDWL         +   DS  P+ +  +K
Sbjct: 25  CRECKDTVCGGKQKSRVNHTFQRREIEAKEACDWLRAAGFPQYAQLYEDSQFPINIVAVK 84

Query: 123 G-----EMSRPGEVCSALNLCESLQKHLAELNHQKQ 153
                 E      +C  LN          ++N Q++
Sbjct: 85  NDHDFLEKDLVEPLCRRLNTLNKCASMKLDVNFQRK 120


>gi|7657671 upstream binding transcription factor, RNA polymerase I
           isoform a [Homo sapiens]
          Length = 764

 Score = 31.6 bits (70), Expect = 1.9
 Identities = 40/186 (21%), Positives = 74/186 (39%), Gaps = 24/186 (12%)

Query: 299 ELVEPIKKHEVPAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLP------ 352
           +L++  KK ++P K     ++     K+V   +  + T KE+ D+  K  S+L       
Sbjct: 185 DLIQNAKKSDIPEKPKTPQQLWYTHEKKVYLKVRPDATTKEVKDSLGKQWSQLSDKKRLK 244

Query: 353 ---KSLSE--ECQEVVDTYGSSILSILLEEVSPELVCSMLHLCSGTRLPALTVHVTQPKD 407
              K+L +  E +E++  Y      + + E    +  S L               T+P  
Sbjct: 245 WIHKALEQRKEYEEIMRDYIQKHPELNISEEG--ITKSTLTKAERQLKDKFDGRPTKPPP 302

Query: 408 GGFCEVCKKLVGYLD-----RNLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYEP 462
             +   C +L+  +        +   S + ++L+  EK      D Y K+CDQ   +YE 
Sbjct: 303 NSYSLYCAELMANMKDVPSTERMVLCSQQWKLLSQKEK------DAYHKKCDQKKKDYEV 356

Query: 463 VLIEIL 468
            L+  L
Sbjct: 357 ELLRFL 362


>gi|29788760 diacylglycerol kinase, eta isoform 1 [Homo sapiens]
          Length = 1164

 Score = 31.2 bits (69), Expect = 2.4
 Identities = 35/151 (23%), Positives = 59/151 (39%), Gaps = 15/151 (9%)

Query: 309 VPAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQEV-VDTYG 367
           V + +   CE  +  V +V K  D       + DA    CS L + L +  Q +  D+  
Sbjct: 508 VISSAKTLCETVKDFVAKVEKTYDKTLENAVVADAVASKCSVLNEKLEQLLQALHTDSQA 567

Query: 368 SSIL----SILLEEVSPELVCSMLHLCSGTRLPALTVHVTQPKDGGFCEVCKKLVGYLDR 423
           + +L     +++EE   + V S      G     L   VT+P         +K V   + 
Sbjct: 568 APVLPGLSPLIVEE---DAVESSSEESLGESKEQLGDDVTKPSS-------QKAVKPREI 617

Query: 424 NLEKNSTKQEILAALEKGCSFLPDPYQKQCD 454
            L  NS K+ +   +E+    + DP    C+
Sbjct: 618 MLRANSLKKAVRQVIEEAGKVMDDPTVHPCE 648


>gi|29788751 diacylglycerol kinase, eta isoform 2 [Homo sapiens]
          Length = 1220

 Score = 31.2 bits (69), Expect = 2.4
 Identities = 35/151 (23%), Positives = 59/151 (39%), Gaps = 15/151 (9%)

Query: 309 VPAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQEV-VDTYG 367
           V + +   CE  +  V +V K  D       + DA    CS L + L +  Q +  D+  
Sbjct: 508 VISSAKTLCETVKDFVAKVEKTYDKTLENAVVADAVASKCSVLNEKLEQLLQALHTDSQA 567

Query: 368 SSIL----SILLEEVSPELVCSMLHLCSGTRLPALTVHVTQPKDGGFCEVCKKLVGYLDR 423
           + +L     +++EE   + V S      G     L   VT+P         +K V   + 
Sbjct: 568 APVLPGLSPLIVEE---DAVESSSEESLGESKEQLGDDVTKPSS-------QKAVKPREI 617

Query: 424 NLEKNSTKQEILAALEKGCSFLPDPYQKQCD 454
            L  NS K+ +   +E+    + DP    C+
Sbjct: 618 MLRANSLKKAVRQVIEEAGKVMDDPTVHPCE 648


>gi|32967605 bromodomain adjacent to zinc finger domain, 1A isoform
           b [Homo sapiens]
          Length = 1524

 Score = 31.2 bits (69), Expect = 2.4
 Identities = 33/146 (22%), Positives = 66/146 (45%), Gaps = 10/146 (6%)

Query: 273 CDEVKEMPMQTLVPAKVASKNVIPALELVEPIKKHEVPAKSDVYCEVCEFLVKEV-TKLI 331
           CD++KE+P  T V  ++  +    AL ++E +  +      D+  E  + +  EV  + +
Sbjct: 404 CDDLKELPEPTPVKTRLPPEIFGDALMVLEFL--NAFGELFDLQDEFPDGVTLEVLEEAL 461

Query: 332 DNNKTEKEILDAFDKMCSKLPKSLSEECQEV-------VDTYGSSILSILLEEVSPELVC 384
             N +E  + +      + + ++++EE +EV        DT G S+ S+ L+  +   + 
Sbjct: 462 VGNDSEGPLCELLFFFLTAIFQAIAEEEEEVAKEQLTDADTKGCSLKSLDLDSCTLSEIL 521

Query: 385 SMLHLCSGTRLPALTVHVTQPKDGGF 410
            +  L SG  + +        K GGF
Sbjct: 522 RLHILASGADVTSANAKYRYQKRGGF 547


>gi|121583483 phosphatidylinositol-3-phosphate 5-kinase type III
            isoform 2 [Homo sapiens]
          Length = 2098

 Score = 30.8 bits (68), Expect = 3.2
 Identities = 19/61 (31%), Positives = 30/61 (49%)

Query: 417  LVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYEPVLIEILVEVMDPSF 476
            L+G  D  +++ ST + I A L  G S+ P P+    D+    YE   + I V   +PS 
Sbjct: 1610 LLGSTDSQVKEKSTMKAIFANLLPGNSYNPIPFPFDPDKHYLMYEHERVPIAVCEKEPSS 1669

Query: 477  V 477
            +
Sbjct: 1670 I 1670


>gi|34915994 transducin-like enhancer protein 4 [Homo sapiens]
          Length = 773

 Score = 30.8 bits (68), Expect = 3.2
 Identities = 28/125 (22%), Positives = 55/125 (44%), Gaps = 15/125 (12%)

Query: 179 LYPQDGPRSKPQPKD--NGDVCQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPG 236
           +YPQ    +  QP       + + C ++  + Q        F+QA    +K EC++L   
Sbjct: 8   MYPQTRHPAPHQPAQPFKFTISESCDRIKEEFQ--------FLQAQYHSLKLECEKLASE 59

Query: 237 MADICKNYISQYSEIAIQMMMHMDQQPKEICALVGFCDEV----KEMPMQTLVPAKVASK 292
             ++ ++Y+  Y E++  + + M +Q + +  L   C +V     +   Q +V A   +K
Sbjct: 60  KTEMQRHYV-MYYEMSYGLNIEMHKQAEIVKRLNAICAQVIPFLSQEHQQQVVQAVERAK 118

Query: 293 NVIPA 297
            V  A
Sbjct: 119 QVTMA 123


>gi|7706254 NOP58 ribonucleoprotein homolog [Homo sapiens]
          Length = 529

 Score = 30.4 bits (67), Expect = 4.2
 Identities = 21/67 (31%), Positives = 33/67 (49%), Gaps = 1/67 (1%)

Query: 326 EVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSILSILL-EEVSPELVC 384
           E+ K+I +N T  + L       +     LSE   E V+    +   I +  EVS E +C
Sbjct: 193 ELGKIISDNLTYCKCLQKVGDRKNYASAKLSELLPEEVEAEVKAAAEISMGTEVSEEDIC 252

Query: 385 SMLHLCS 391
           ++LHLC+
Sbjct: 253 NILHLCT 259


>gi|224831239 integrin alpha M isoform 1 precursor [Homo sapiens]
          Length = 1153

 Score = 30.0 bits (66), Expect = 5.4
 Identities = 25/94 (26%), Positives = 40/94 (42%), Gaps = 11/94 (11%)

Query: 382 LVCSMLHLCSGTRLPALTVHVTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKG 441
           L+ + L LC G  L        Q    GF +   +L G    +       QEI+AA ++G
Sbjct: 6   LLLTALTLCHGFNLDTENAMTFQENARGFGQSVVQLQG----SRVVVGAPQEIVAANQRG 61

Query: 442 CSFLPDPYQKQCDQFVAEYEPVLIEILVEVMDPS 475
             +       QCD      EP+ +++ VE ++ S
Sbjct: 62  SLY-------QCDYSTGSCEPIRLQVPVEAVNMS 88


>gi|7108344 granulysin isoform NKG5 [Homo sapiens]
          Length = 145

 Score = 30.0 bits (66), Expect = 5.4
 Identities = 15/71 (21%), Positives = 35/71 (49%), Gaps = 1/71 (1%)

Query: 320 CEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSILSILLEEVS 379
           C  +V+++ K++D   T++ + +A  ++C        + C+  +  Y S +   L+   +
Sbjct: 69  CLTIVQKLKKMVDK-PTQRSVSNAATRVCRTGRSRWRDVCRNFMRRYQSRVTQGLVAGET 127

Query: 380 PELVCSMLHLC 390
            + +C  L LC
Sbjct: 128 AQQICEDLRLC 138


>gi|157502222 granulysin isoform 519 [Homo sapiens]
          Length = 130

 Score = 30.0 bits (66), Expect = 5.4
 Identities = 15/71 (21%), Positives = 35/71 (49%), Gaps = 1/71 (1%)

Query: 320 CEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSILSILLEEVS 379
           C  +V+++ K++D   T++ + +A  ++C        + C+  +  Y S +   L+   +
Sbjct: 54  CLTIVQKLKKMVDK-PTQRSVSNAATRVCRTGRSRWRDVCRNFMRRYQSRVTQGLVAGET 112

Query: 380 PELVCSMLHLC 390
            + +C  L LC
Sbjct: 113 AQQICEDLRLC 123


>gi|88501734 integrin alpha M isoform 2 precursor [Homo sapiens]
          Length = 1152

 Score = 30.0 bits (66), Expect = 5.4
 Identities = 25/94 (26%), Positives = 40/94 (42%), Gaps = 11/94 (11%)

Query: 382 LVCSMLHLCSGTRLPALTVHVTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKG 441
           L+ + L LC G  L        Q    GF +   +L G    +       QEI+AA ++G
Sbjct: 6   LLLTALTLCHGFNLDTENAMTFQENARGFGQSVVQLQG----SRVVVGAPQEIVAANQRG 61

Query: 442 CSFLPDPYQKQCDQFVAEYEPVLIEILVEVMDPS 475
             +       QCD      EP+ +++ VE ++ S
Sbjct: 62  SLY-------QCDYSTGSCEPIRLQVPVEAVNMS 88


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.134    0.413 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,649,930
Number of Sequences: 37866
Number of extensions: 1005133
Number of successful extensions: 2826
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 11
Number of HSP's successfully gapped in prelim test: 31
Number of HSP's that attempted gapping in prelim test: 2731
Number of HSP's gapped (non-prelim): 68
length of query: 526
length of database: 18,247,518
effective HSP length: 107
effective length of query: 419
effective length of database: 14,195,856
effective search space: 5948063664
effective search space used: 5948063664
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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